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Search of human proteins with 148664218
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|148664218 POU transcription factor [Homo sapiens]
(436 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|148664218 POU transcription factor [Homo sapiens] 881 0.0
gi|4505959 POU domain, class 2, transcription factor 2 [Homo sap... 325 5e-89
gi|42476164 POU class 2 homeobox 1 [Homo sapiens] 291 6e-79
gi|110624765 POU domain, class 3, transcription factor 1 [Homo s... 207 2e-53
gi|51702521 POU domain, class 3, transcription factor 2 [Homo sa... 202 4e-52
gi|5453936 POU class 3 homeobox 3 [Homo sapiens] 202 5e-52
gi|110624763 POU domain, class 3, transcription factor 4 [Homo s... 199 3e-51
gi|42560248 POU domain, class 5, transcription factor 1 isoform ... 166 3e-41
gi|116235491 POU domain, class 5, transcription factor 1 isoform... 164 1e-40
gi|227430410 POU class 5 homeobox 1B [Homo sapiens] 162 6e-40
gi|170650730 pituitary specific transcription factor 1 isoform b... 159 5e-39
gi|4505955 pituitary specific transcription factor 1 isoform alp... 159 5e-39
gi|110347455 Brn3b POU domain transcription factor [Homo sapiens] 145 9e-35
gi|4505965 POU class 4 homeobox 3 [Homo sapiens] 143 3e-34
gi|110347449 POU domain, class 4, transcription factor 1 [Homo s... 140 2e-33
gi|223890225 POU class 6 homeobox 1 [Homo sapiens] 127 3e-29
gi|23463326 POU domain class 5, transcription factor 2 [Homo sap... 122 8e-28
gi|157743257 POU domain, class 6, transcription factor 2 [Homo s... 110 3e-24
gi|149588930 gastrulation brain homeo box 1 [Homo sapiens] 58 1e-08
gi|126090663 zinc finger homeodomain 4 [Homo sapiens] 50 4e-06
gi|31377777 NK2 homeobox 8 [Homo sapiens] 50 5e-06
gi|45593144 gastrulation brain homeo box 2 [Homo sapiens] 49 9e-06
gi|63054872 ladybird homeobox 1 [Homo sapiens] 48 2e-05
gi|11641283 LIM homeobox protein 5 [Homo sapiens] 47 3e-05
gi|15375314 LIM homeobox protein 4 [Homo sapiens] 47 4e-05
gi|30410785 LIM homeobox protein 1 [Homo sapiens] 47 4e-05
gi|116517292 cut-like 2 [Homo sapiens] 46 6e-05
gi|24497589 aristaless related homeobox [Homo sapiens] 46 6e-05
gi|4758090 NK2 transcription factor related, locus 5 [Homo sapiens] 46 8e-05
gi|121114296 caudal type homeobox 1 [Homo sapiens] 46 8e-05
>gi|148664218 POU transcription factor [Homo sapiens]
Length = 436
Score = 881 bits (2276), Expect = 0.0
Identities = 436/436 (100%), Positives = 436/436 (100%)
Query: 1 MVNLESMHTDIKMSGDVADSTDARSTLSQVEPGNDRNGLDFNRQIKTEDLSDSLQQTLSH 60
MVNLESMHTDIKMSGDVADSTDARSTLSQVEPGNDRNGLDFNRQIKTEDLSDSLQQTLSH
Sbjct: 1 MVNLESMHTDIKMSGDVADSTDARSTLSQVEPGNDRNGLDFNRQIKTEDLSDSLQQTLSH 60
Query: 61 RPCHLSQGPAMMSGNQMSGLNASPCQDMASLHPLQQLVLVPGHLQSVSQFLLSQTQPGQQ 120
RPCHLSQGPAMMSGNQMSGLNASPCQDMASLHPLQQLVLVPGHLQSVSQFLLSQTQPGQQ
Sbjct: 61 RPCHLSQGPAMMSGNQMSGLNASPCQDMASLHPLQQLVLVPGHLQSVSQFLLSQTQPGQQ 120
Query: 121 GLQPNLLPFPQQQSGLLLPQTGPGLASQAFGHPGLPGSSLEPHLEASQHLPVPKHLPSSG 180
GLQPNLLPFPQQQSGLLLPQTGPGLASQAFGHPGLPGSSLEPHLEASQHLPVPKHLPSSG
Sbjct: 121 GLQPNLLPFPQQQSGLLLPQTGPGLASQAFGHPGLPGSSLEPHLEASQHLPVPKHLPSSG 180
Query: 181 GADEPSDLEELEKFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFK 240
GADEPSDLEELEKFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFK
Sbjct: 181 GADEPSDLEELEKFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFK 240
Query: 241 NMCKLKPLLEKWLNDAESSPSDPSVSTPSSYPSLSEVFGRKRKKRTSIETNIRLTLEKRF 300
NMCKLKPLLEKWLNDAESSPSDPSVSTPSSYPSLSEVFGRKRKKRTSIETNIRLTLEKRF
Sbjct: 241 NMCKLKPLLEKWLNDAESSPSDPSVSTPSSYPSLSEVFGRKRKKRTSIETNIRLTLEKRF 300
Query: 301 QDNPKPSSEEISMIAEQLSMEKEVVRVWFCNRRQKEKRINCPVATPIKPPVYNSRLVSPS 360
QDNPKPSSEEISMIAEQLSMEKEVVRVWFCNRRQKEKRINCPVATPIKPPVYNSRLVSPS
Sbjct: 301 QDNPKPSSEEISMIAEQLSMEKEVVRVWFCNRRQKEKRINCPVATPIKPPVYNSRLVSPS 360
Query: 361 GSLGPLSVPPVHSTMPGTVTSSCSPGNNSRPSSPGSGLHASSPTASQNNSKAAVNSASSF 420
GSLGPLSVPPVHSTMPGTVTSSCSPGNNSRPSSPGSGLHASSPTASQNNSKAAVNSASSF
Sbjct: 361 GSLGPLSVPPVHSTMPGTVTSSCSPGNNSRPSSPGSGLHASSPTASQNNSKAAVNSASSF 420
Query: 421 NSSGSWYRWNHSTYLH 436
NSSGSWYRWNHSTYLH
Sbjct: 421 NSSGSWYRWNHSTYLH 436
>gi|4505959 POU domain, class 2, transcription factor 2 [Homo
sapiens]
Length = 463
Score = 325 bits (833), Expect = 5e-89
Identities = 218/447 (48%), Positives = 261/447 (58%), Gaps = 55/447 (12%)
Query: 6 SMHTDIKMSGDVADSTDARSTLS--QVEPGNDRNGLDFNRQIKTEDLS-DSLQQT-LSHR 61
S HTD + +G + + ++ S V P + +IK ED S DS L +
Sbjct: 28 SEHTDTERNGPDTNHQNPQNKTSPFSVSPTGP------STKIKAEDPSGDSAPAAPLPPQ 81
Query: 62 PC--HLSQGPAMMSGNQMSGLNASPCQDMASLHPLQQLVLVPGH-LQSVSQFLLSQTQPG 118
P HL Q M++G+Q++G D+ L LQQLVLVPGH LQ +QFLL Q Q
Sbjct: 82 PAQPHLPQAQLMLTGSQLAG-------DIQQLLQLQQLVLVPGHHLQPPAQFLLPQAQQS 134
Query: 119 QQGL--QPNLLPFPQQQSGLLLPQTGPGLASQAFGHPGLPGSSLEPHLEASQHLPVPKHL 176
Q GL PNL PQQ G LL + G P P LEP P H
Sbjct: 135 QPGLLPTPNLFQLPQQTQGALLT------SQPRAGLPTQPPKCLEP----------PSH- 177
Query: 177 PSSGGADEPSDLEELEKFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALN 236
+EPSDLEELE+FA+TFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALN
Sbjct: 178 -----PEEPSDLEELEQFARTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALN 232
Query: 237 LSFKNMCKLKPLLEKWLNDAESSPSDPSVSTPSSYPSLSEVF----GRKRKKRTSIETNI 292
LSFKNMCKLKPLLEKWLNDAE+ D S+ +P+ S S F GR+RKKRTSIETN+
Sbjct: 233 LSFKNMCKLKPLLEKWLNDAETMSVDSSLPSPNQLSSPSLGFDGLPGRRRKKRTSIETNV 292
Query: 293 RLTLEKRFQDNPKPSSEEISMIAEQLSMEKEVVRVWFCNRRQKEKRIN-CPVA----TPI 347
R LEK F N KP+SEEI +IAEQL MEKEV+RVWFCNRRQKEKRIN C A +P
Sbjct: 293 RFALEKSFLANQKPTSEEILLIAEQLHMEKEVIRVWFCNRRQKEKRINPCSAAPMLPSPG 352
Query: 348 KPPVYNSRLVSPSGSLGPLSVPPVHSTMPGTVTSSCSPGNNSRPSSPGSGLHASSPTASQ 407
KP Y+ +V+P G G L + S++ TVT+ S PS G A
Sbjct: 353 KPASYSPHMVTPQGGAGTLPLSQASSSLSTTVTTLSSAVGTLHPSRTAGGGGGGGGAAPP 412
Query: 408 NNSKAAVN--SASSFNSSGSWYRWNHS 432
NS +V ++ NS+ + +HS
Sbjct: 413 LNSIPSVTPPPPATTNSTNPSPQGSHS 439
>gi|42476164 POU class 2 homeobox 1 [Homo sapiens]
Length = 743
Score = 291 bits (746), Expect = 6e-79
Identities = 186/352 (52%), Positives = 229/352 (65%), Gaps = 25/352 (7%)
Query: 94 LQQLVLV-PGHLQSVSQFLLSQTQPGQQGL---QPNLLPFPQQ-QSGLLLPQTGPGLASQ 148
LQQ VLV P +QF++SQT GQQGL Q L PQQ Q+ LL Q L SQ
Sbjct: 189 LQQFVLVHPTTNLQPAQFIISQTPQGQQGLLQAQNLLTQLPQQSQANLLQSQPSITLTSQ 248
Query: 149 AFGHPGLPGSSLE--PHLEASQHLPVPKHLPSSGGADEPSDLEELEKFAKTFKQRRIKLG 206
P P ++ P Q PK + + +EPSDLEELE+FAKTFKQRRIKLG
Sbjct: 249 ----PATPTRTIAATPIQTLPQSQSTPKRIDTPS-LEEPSDLEELEQFAKTFKQRRIKLG 303
Query: 207 FTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLNDAESSPSDPSVS 266
FTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLNDAE+ SD S+S
Sbjct: 304 FTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLNDAENLSSDSSLS 363
Query: 267 TPSSYPSLS-EVFGRKRKKRTSIETNIRLTLEKRFQDNPKPSSEEISMIAEQLSMEKEVV 325
+PS+ S E R+RKKRTSIETNIR+ LEK F +N KP+SEEI+MIA+QL+MEKEV+
Sbjct: 364 SPSALNSPGIEGLSRRRKKRTSIETNIRVALEKSFLENQKPTSEEITMIADQLNMEKEVI 423
Query: 326 RVWFCNRRQKEKRINCP-----VATPIK---PPVYNSRLVSP----SGSLGPLSVPPVHS 373
RVWFCNRRQKEKRIN P ++PIK P + +P S + L+V PV
Sbjct: 424 RVWFCNRRQKEKRINPPSSGGTSSSPIKAIFPSPTSLVATTPSLVTSSAATTLTVSPVLP 483
Query: 374 TMPGTVTSSCSPGNNSRPSSPGSGLHASSPTASQNNSKAAVNSASSFNSSGS 425
VT+ G + S+ + + +++P AS + +++ + S ++S S
Sbjct: 484 LTSAAVTNLSVTGTSDTTSNNTATVISTAPPASSAVTSPSLSPSPSASASTS 535
>gi|110624765 POU domain, class 3, transcription factor 1 [Homo
sapiens]
Length = 451
Score = 207 bits (527), Expect = 2e-53
Identities = 135/277 (48%), Positives = 157/277 (56%), Gaps = 49/277 (17%)
Query: 142 GPGL--ASQAFGHPGLPGSSLEPHLEASQHLPVPKHL-----------PSSGGA------ 182
GPGL A GH S PHL A H H P +GG
Sbjct: 184 GPGLHHALHEDGHEAQLEPSPPPHLGAHGHAHGHAHAGGLHAAAAHLHPGAGGGGSSVGE 243
Query: 183 ----DEPSDLEELEKFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLS 238
D PS ++LE+FAK FKQRRIKLGFTQ DVGLA+G LYGN FSQTTI RFEAL LS
Sbjct: 244 HSDEDAPSS-DDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLS 302
Query: 239 FKNMCKLKPLLEKWLNDAESSPSDPSVSTPSSYPSLSEVF--GRKRKKRTSIETNIRLTL 296
FKNMCKLKPLL KWL + +SS P+ +L ++ GRKRKKRTSIE ++ L
Sbjct: 303 FKNMCKLKPLLNKWLEETDSSSGSPT--------NLDKIAAQGRKRKKRTSIEVGVKGAL 354
Query: 297 EKRFQDNPKPSSEEISMIAEQLSMEKEVVRVWFCNRRQKEKRINCPVATPIKPP---VYN 353
E F PKPS+ EI+ +A+ L +EKEVVRVWFCNRRQKEKR+ P A PP VY
Sbjct: 355 ESHFLKCPKPSAHEITGLADSLQLEKEVVRVWFCNRRQKEKRMT-PAAGAGHPPMDDVYA 413
Query: 354 SRLVSP-SGSLGPLSVPPV----------HSTMPGTV 379
+ P G P S PP H T+PG+V
Sbjct: 414 PGELGPGGGGASPPSAPPPPPPAALHHHHHHTLPGSV 450
>gi|51702521 POU domain, class 3, transcription factor 2 [Homo
sapiens]
Length = 443
Score = 202 bits (515), Expect = 4e-52
Identities = 121/247 (48%), Positives = 148/247 (59%), Gaps = 37/247 (14%)
Query: 116 QPGQQGLQPNLLPFPQQQSGLLLPQTGPGLASQAFGHPGLPGSSLEPHLEASQHLPVPKH 175
+P P+ P QQ P GP PG PG+ +PH +
Sbjct: 221 EPHHADHHPHPHSHPHQQPPPPPPPQGP---------PGHPGAHHDPHSDE--------- 262
Query: 176 LPSSGGADEPSDLEELEKFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEAL 235
D P+ ++LE+FAK FKQRRIKLGFTQ DVGLA+G LYGN FSQTTI RFEAL
Sbjct: 263 -------DTPTS-DDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEAL 314
Query: 236 NLSFKNMCKLKPLLEKWLNDAESSPSDPSVSTPSSYPSLSEVF--GRKRKKRTSIETNIR 293
LSFKNMCKLKPLL KWL +A+SS P+ S+ ++ GRKRKKRTSIE +++
Sbjct: 315 QLSFKNMCKLKPLLNKWLEEADSSSGSPT--------SIDKIAAQGRKRKKRTSIEVSVK 366
Query: 294 LTLEKRFQDNPKPSSEEISMIAEQLSMEKEVVRVWFCNRRQKEKRINCPVAT-PIKPPVY 352
LE F PKPS++EI+ +A+ L +EKEVVRVWFCNRRQKEKR+ P T P VY
Sbjct: 367 GALESHFLKCPKPSAQEITSLADSLQLEKEVVRVWFCNRRQKEKRMTPPGGTLPGAEDVY 426
Query: 353 NSRLVSP 359
+P
Sbjct: 427 GGSRDTP 433
>gi|5453936 POU class 3 homeobox 3 [Homo sapiens]
Length = 500
Score = 202 bits (514), Expect = 5e-52
Identities = 126/259 (48%), Positives = 154/259 (59%), Gaps = 39/259 (15%)
Query: 142 GPGLASQAFGHPGLP-GSSLE-------PHLEASQHLPVPKHL---PSSGGA-------- 182
G G +Q+ HPGL G + E H A H P P H P GG
Sbjct: 246 GAGGGAQSLVHPGLVRGDTPELAEHHHHHHHHAHPHPPHPHHAQGPPHHGGGGGGAGPGL 305
Query: 183 ---------DEPSDLEELEKFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFE 233
D P+ ++LE+FAK FKQRRIKLGFTQ DVGLA+G LYGN FSQTTI RFE
Sbjct: 306 NSHDPHSDEDTPTS-DDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFE 364
Query: 234 ALNLSFKNMCKLKPLLEKWLNDAESSPSDPSVSTPSSYPSLSEVFGRKRKKRTSIETNIR 293
AL LSFKNMCKLKPLL KWL +A+S S +P+S ++ GRKRKKRTSIE +++
Sbjct: 365 ALQLSFKNMCKLKPLLNKWLEEADS-----STGSPTSIDKIA-AQGRKRKKRTSIEVSVK 418
Query: 294 LTLEKRFQDNPKPSSEEISMIAEQLSMEKEVVRVWFCNRRQKEKRINCPVATPIKPPVYN 353
LE F PKPS++EI+ +A+ L +EKEVVRVWFCNRRQKEKR+ P P
Sbjct: 419 GALESHFLKCPKPSAQEITNLADSLQLEKEVVRVWFCNRRQKEKRMTPPGIQQQTP---- 474
Query: 354 SRLVSPSGSLGPLSVPPVH 372
+ S G++ + PP H
Sbjct: 475 DDVYSQVGTVSADTPPPHH 493
>gi|110624763 POU domain, class 3, transcription factor 4 [Homo
sapiens]
Length = 361
Score = 199 bits (507), Expect = 3e-51
Identities = 118/232 (50%), Positives = 141/232 (60%), Gaps = 16/232 (6%)
Query: 111 LLSQTQPGQQGLQPNLLPFPQQQSGLLLPQTGPGLASQAFGHPGLPGSSLEPHLEASQHL 170
+ S QP QP + G L P P AS HP L E H
Sbjct: 124 ITSSGQPLNVYSQPGFTVSGMLEHGGLTPP--PAAASAQSLHPVLR--------EPPDHG 173
Query: 171 PVPKHLPSSGGADEPSDLEELEKFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTIS 230
+ H +E +ELE+FAK FKQRRIKLGFTQ DVGLA+G LYGN FSQTTI
Sbjct: 174 ELGSHHCQDHSDEETPTSDELEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTIC 233
Query: 231 RFEALNLSFKNMCKLKPLLEKWLNDAESSPSDPSVSTPSSYPSLSEVFGRKRKKRTSIET 290
RFE L LSFKNMCKLKPLL KWL +A+S S +P+S ++ GRKRKKRTSIE
Sbjct: 234 RFEGLQLSFKNMCKLKPLLNKWLEEADS-----STGSPTSIDKIA-AQGRKRKKRTSIEV 287
Query: 291 NIRLTLEKRFQDNPKPSSEEISMIAEQLSMEKEVVRVWFCNRRQKEKRINCP 342
+++ LE F PKP+++EIS +A+ L +EKEVVRVWFCNRRQKEKR+ P
Sbjct: 288 SVKGVLETHFLKCPKPAAQEISSLADSLQLEKEVVRVWFCNRRQKEKRMTPP 339
>gi|42560248 POU domain, class 5, transcription factor 1 isoform 1
[Homo sapiens]
Length = 360
Score = 166 bits (421), Expect = 3e-41
Identities = 99/216 (45%), Positives = 129/216 (59%), Gaps = 22/216 (10%)
Query: 139 PQTGPGLASQAFGHPGLPGSSLEPHLEASQHLPVPKHLPSSGGA------------DEPS 186
PQ G GL Q P +E++ P+ + GA +E
Sbjct: 78 PQVGVGLVPQGGLETSQPEGEAGVGVESNSDGASPEPCTVTPGAVKLEKEKLEQNPEESQ 137
Query: 187 DLE----ELEKFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNM 242
D++ ELE+FAK KQ+RI LG+TQ DVGL +G L+G FSQTTI RFEAL LSFKNM
Sbjct: 138 DIKALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTICRFEALQLSFKNM 197
Query: 243 CKLKPLLEKWLNDAESSPSDPSVSTPSSYPSLSEVFGRKRKKRTSIETNIRLTLEKRFQD 302
CKL+PLL+KW+ +A+++ + + + V RKR KRTSIE +R LE F
Sbjct: 198 CKLRPLLQKWVEEADNNENLQEICKAETL-----VQARKR-KRTSIENRVRGNLENLFLQ 251
Query: 303 NPKPSSEEISMIAEQLSMEKEVVRVWFCNRRQKEKR 338
PKP+ ++IS IA+QL +EK+VVRVWFCNRRQK KR
Sbjct: 252 CPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKR 287
>gi|116235491 POU domain, class 5, transcription factor 1 isoform 2
[Homo sapiens]
Length = 265
Score = 164 bits (416), Expect = 1e-40
Identities = 86/150 (57%), Positives = 109/150 (72%), Gaps = 6/150 (4%)
Query: 189 EELEKFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPL 248
+ELE+FAK KQ+RI LG+TQ DVGL +G L+G FSQTTI RFEAL LSFKNMCKL+PL
Sbjct: 49 KELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTICRFEALQLSFKNMCKLRPL 108
Query: 249 LEKWLNDAESSPSDPSVSTPSSYPSLSEVFGRKRKKRTSIETNIRLTLEKRFQDNPKPSS 308
L+KW+ +A+++ + + + V RKR KRTSIE +R LE F PKP+
Sbjct: 109 LQKWVEEADNNENLQEICKAETL-----VQARKR-KRTSIENRVRGNLENLFLQCPKPTL 162
Query: 309 EEISMIAEQLSMEKEVVRVWFCNRRQKEKR 338
++IS IA+QL +EK+VVRVWFCNRRQK KR
Sbjct: 163 QQISHIAQQLGLEKDVVRVWFCNRRQKGKR 192
>gi|227430410 POU class 5 homeobox 1B [Homo sapiens]
Length = 359
Score = 162 bits (410), Expect = 6e-40
Identities = 117/310 (37%), Positives = 158/310 (50%), Gaps = 46/310 (14%)
Query: 101 PGHLQSVSQFLLSQTQPGQQGLQPNL-----------LPFPQQQSGLLL---PQTGPGLA 146
PG + ++ +L Q PG G+ P + P P + G + PQ G GL
Sbjct: 27 PGWVDPLT-WLSFQGPPGGPGIGPGVGPGSEVWGIPPCPPPYELCGGMAYCGPQVGVGLV 85
Query: 147 SQAFGHPGLPGSSLEPHLEASQH--LPVPKHLPSSGGADEPSDLE--------------E 190
Q P S +E++ + P P +P E LE E
Sbjct: 86 PQGGLETSQPESEAGVGVESNSNGASPEPCTVPPGAVKLEKEKLEQNPEKSQDIKALQKE 145
Query: 191 LEKFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLE 250
LE+FAK KQ+RI LG+TQ DVGL +G L+G FSQ TI RFEAL LSFKNMCKL+PLL+
Sbjct: 146 LEQFAKLLKQKRITLGYTQADVGLILGVLFGKVFSQKTICRFEALQLSFKNMCKLRPLLQ 205
Query: 251 KWLNDAESSPSDPSVSTPSSYPSLSEVFGRKRKKRTSIETNIRLTLEKRFQDNPKPSSEE 310
KW+ +A+++ + + + + +++KRTSIE +R LE F PKP+ +
Sbjct: 206 KWVEEADNNENLQEICKAET------LMQARKRKRTSIENRVRGNLENLFLQCPKPTL-Q 258
Query: 311 ISMIAEQLSMEKEVVRVWFCNRRQKEKRINCPVATPIKPPVYNSRLVSPSGSLGPLSVPP 370
IS IA+QL +EK+VVRVWFCNRRQK KR + A + S GP+S PP
Sbjct: 259 ISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQR-----EDFEAAGSPFSGGPVSFPP 313
Query: 371 V---HSTMPG 377
H PG
Sbjct: 314 APGPHFGTPG 323
>gi|170650730 pituitary specific transcription factor 1 isoform beta
[Homo sapiens]
Length = 317
Score = 159 bits (402), Expect = 5e-39
Identities = 85/162 (52%), Positives = 110/162 (67%), Gaps = 13/162 (8%)
Query: 183 DEPSDLE-----ELEKFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNL 237
+EP D++ ELEKFA FK RRIKLG+TQ +VG A+ ++G++FSQTTI RFE L L
Sbjct: 145 EEPIDMDSPEIRELEKFANEFKVRRIKLGYTQTNVGEALAAVHGSEFSQTTICRFENLQL 204
Query: 238 SFKNMCKLKPLLEKWLNDAESSPSDPSVSTPSSYPSLSEVFGRKRKKRTSIETNIRLTLE 297
SFKN CKLK +L KWL +AE + Y RKRK+RT+I + LE
Sbjct: 205 SFKNACKLKAILSKWLEEAE--------QVGALYNEKVGANERKRKRRTTISIAAKDALE 256
Query: 298 KRFQDNPKPSSEEISMIAEQLSMEKEVVRVWFCNRRQKEKRI 339
+ F + KPSS+EI +AE+L++EKEVVRVWFCNRRQ+EKR+
Sbjct: 257 RHFGEQNKPSSQEIMRMAEELNLEKEVVRVWFCNRRQREKRV 298
>gi|4505955 pituitary specific transcription factor 1 isoform alpha
[Homo sapiens]
Length = 291
Score = 159 bits (402), Expect = 5e-39
Identities = 85/162 (52%), Positives = 110/162 (67%), Gaps = 13/162 (8%)
Query: 183 DEPSDLE-----ELEKFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNL 237
+EP D++ ELEKFA FK RRIKLG+TQ +VG A+ ++G++FSQTTI RFE L L
Sbjct: 119 EEPIDMDSPEIRELEKFANEFKVRRIKLGYTQTNVGEALAAVHGSEFSQTTICRFENLQL 178
Query: 238 SFKNMCKLKPLLEKWLNDAESSPSDPSVSTPSSYPSLSEVFGRKRKKRTSIETNIRLTLE 297
SFKN CKLK +L KWL +AE + Y RKRK+RT+I + LE
Sbjct: 179 SFKNACKLKAILSKWLEEAE--------QVGALYNEKVGANERKRKRRTTISIAAKDALE 230
Query: 298 KRFQDNPKPSSEEISMIAEQLSMEKEVVRVWFCNRRQKEKRI 339
+ F + KPSS+EI +AE+L++EKEVVRVWFCNRRQ+EKR+
Sbjct: 231 RHFGEQNKPSSQEIMRMAEELNLEKEVVRVWFCNRRQREKRV 272
>gi|110347455 Brn3b POU domain transcription factor [Homo sapiens]
Length = 409
Score = 145 bits (365), Expect = 9e-35
Identities = 94/224 (41%), Positives = 127/224 (56%), Gaps = 21/224 (9%)
Query: 131 QQQSGLLLPQTGPGLASQAFGHP-----GLPG-----SSLEPHLEASQHLPVPKHLPSSG 180
Q G LL PGLA A P P +++ P +A+ + LPS
Sbjct: 186 QALEGELLEHLSPGLALGAMAGPDGAVVSTPAHAPHMATMNPMHQAALSMAHAHGLPSHM 245
Query: 181 G--ADEPSDLEELEKFAKTFKQRRIKLGFTQGDVGLAMGKLY---GNDFSQTTISRFEAL 235
G +D +D +LE FA+ FKQRRIKLG TQ DVG A+ L SQ+TI RFE+L
Sbjct: 246 GCMSDVDADPRDLEAFAERFKQRRIKLGVTQADVGSALANLKIPGVGSLSQSTICRFESL 305
Query: 236 NLSFKNMCKLKPLLEKWLNDAESSPSDPSVSTPSSYPSLSEVFGRKRKKRTSIETNIRLT 295
LS NM LKP+L+ WL +AE S + ++ P + K++KRTSI + +
Sbjct: 306 TLSHNNMIALKPILQAWLEEAEKSHRE-KLTKPELFNG-----AEKKRKRTSIAAPEKRS 359
Query: 296 LEKRFQDNPKPSSEEISMIAEQLSMEKEVVRVWFCNRRQKEKRI 339
LE F P+PSSE+I+ IAE+L ++K VVRVWFCN+RQK+KR+
Sbjct: 360 LEAYFAIQPRPSSEKIAAIAEKLDLKKNVVRVWFCNQRQKQKRM 403
>gi|4505965 POU class 4 homeobox 3 [Homo sapiens]
Length = 338
Score = 143 bits (360), Expect = 3e-34
Identities = 97/231 (41%), Positives = 124/231 (53%), Gaps = 33/231 (14%)
Query: 131 QQQSGLLLPQTGPGLASQAFGHP--GLPGSSLEPHLEASQHLPVPKHLPSSGGADEP--- 185
Q G LL P L+ G P + + + PH HL HL + G P
Sbjct: 113 QGLEGDLLEHISPTLSVSGLGAPEHSVMPAQIHPH-----HLGAMGHLHQAMGMSHPHTV 167
Query: 186 --------------SDLEELEKFAKTFKQRRIKLGFTQGDVGLAMGKLY---GNDFSQTT 228
SD ELE FA+ FKQRRIKLG TQ DVG A+ L SQ+T
Sbjct: 168 APHSAMPACLSDVESDPRELEAFAERFKQRRIKLGVTQADVGAALANLKIPGVGSLSQST 227
Query: 229 ISRFEALNLSFKNMCKLKPLLEKWLNDAESSPSDPSVSTPSSYPSLSEVFGRKRKKRTSI 288
I RFE+L LS NM LKP+L+ WL +AE++ + + S P L RKRK RTSI
Sbjct: 228 ICRFESLTLSHNNMIALKPVLQAWLEEAEAAYREKN-----SKPELFNGSERKRK-RTSI 281
Query: 289 ETNIRLTLEKRFQDNPKPSSEEISMIAEQLSMEKEVVRVWFCNRRQKEKRI 339
+ +LE F P+PSSE+I+ IAE+L ++K VVRVWFCN+RQK+KR+
Sbjct: 282 AAPEKRSLEAYFAIQPRPSSEKIAAIAEKLDLKKNVVRVWFCNQRQKQKRM 332
>gi|110347449 POU domain, class 4, transcription factor 1 [Homo
sapiens]
Length = 419
Score = 140 bits (354), Expect = 2e-33
Identities = 78/160 (48%), Positives = 104/160 (65%), Gaps = 9/160 (5%)
Query: 183 DEPSDLEELEKFAKTFKQRRIKLGFTQGDVGLAMGKLY---GNDFSQTTISRFEALNLSF 239
D +D ELE FA+ FKQRRIKLG TQ DVG A+ L SQ+TI RFE+L LS
Sbjct: 260 DSDTDPRELEAFAERFKQRRIKLGVTQADVGSALANLKIPGVGSLSQSTICRFESLTLSH 319
Query: 240 KNMCKLKPLLEKWLNDAESSPSDPSVSTPSSYPSLSEVFGRKRKKRTSIETNIRLTLEKR 299
NM LKP+L+ WL +AE + + ++ P + G K++KRTSI + +LE
Sbjct: 320 NNMIALKPILQAWLEEAEGAQRE-KMNKPELFNG-----GEKKRKRTSIAAPEKRSLEAY 373
Query: 300 FQDNPKPSSEEISMIAEQLSMEKEVVRVWFCNRRQKEKRI 339
F P+PSSE+I+ IAE+L ++K VVRVWFCN+RQK+KR+
Sbjct: 374 FAVQPRPSSEKIAAIAEKLDLKKNVVRVWFCNQRQKQKRM 413
>gi|223890225 POU class 6 homeobox 1 [Homo sapiens]
Length = 301
Score = 127 bits (318), Expect = 3e-29
Identities = 88/229 (38%), Positives = 121/229 (52%), Gaps = 25/229 (10%)
Query: 117 PGQQGLQPNLLPFPQQQSGLLLPQTGPGLASQAFGHPGLPGSSLEPHLEASQHLPVPKHL 176
P + +QP + P P +PQ +AS A P S+ P P L
Sbjct: 79 PAKSEVQP-IQPTPT------VPQPAVVIASPA---PAAKPSASAPIPITCSETPTVSQL 128
Query: 177 ---PSSGGADEPS-DLEELEKFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRF 232
P + DE +LEE+ +FAK FK RR+ LG TQ VG A+ G +SQ+ I RF
Sbjct: 129 VSKPHTPSLDEDGINLEEIREFAKNFKIRRLSLGLTQTQVGQALTATEGPAYSQSAICRF 188
Query: 233 EALNLSFKNMCKLKPLLEKWLNDAESSPSDPSVSTPSSYPSLSEVFG----RKRKKRTSI 288
E L+++ K+ KLKP+LEKWLN+AE + +L E G +KRK+RTS
Sbjct: 189 EKLDITPKSAQKLKPVLEKWLNEAE-------LRNQEGQQNLMEFVGGEPSKKRKRRTSF 241
Query: 289 ETNIRLTLEKRFQDNPKPSSEEISMIAEQLSMEKEVVRVWFCNRRQKEK 337
L F+ NP P+ +EI+ IA++L+ ++EVVRVWFCNRRQ K
Sbjct: 242 TPQAIEALNAYFEKNPLPTGQEITEIAKELNYDREVVRVWFCNRRQTLK 290
>gi|23463326 POU domain class 5, transcription factor 2 [Homo
sapiens]
Length = 328
Score = 122 bits (305), Expect = 8e-28
Identities = 86/228 (37%), Positives = 121/228 (53%), Gaps = 22/228 (9%)
Query: 117 PGQQGLQPNLLPFPQQQSGLLLP---QTGPGLASQAFGHPG---LPGSSLEPHLEASQHL 170
PG + L P P + G + P + G A P LPG + L + L
Sbjct: 56 PGPDVWRIPLGPLPHEFRGWIAPCRPRLGASEAGDWLRRPSEGALPGPYIA--LRSIPKL 113
Query: 171 PVPKHLPSSGGADEPSDLEELEKFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTIS 230
P P+ D L+EL++ AK +Q+R+ LG++Q DVG+A+G L+G SQTTI
Sbjct: 114 PPPE--------DISGILKELQQLAKELRQKRLSLGYSQADVGIAVGALFGKVLSQTTIC 165
Query: 231 RFEALNLSFKNMCKLKPLLEKWLNDAESSPSDPSVSTPSSYPSLSEVFGRKRKKRTSIET 290
RFEA LS NM KL+PLL+KWL + E+ ++ + + G+ R R S E
Sbjct: 166 RFEAQQLSVANMWKLRPLLKKWLKEVEAE----NLLGLCKMEMILQQSGKWR--RASRER 219
Query: 291 NIRLTLEKRFQDNPKPSSEEISMIAEQLSMEKEVVRVWFCNRRQKEKR 338
I +LEK FQ PKP+ ++IS IA L ++K+VVRVWF NR + R
Sbjct: 220 RIGNSLEKFFQRCPKPTPQQISHIAGCLQLQKDVVRVWFYNRSKMGSR 267
>gi|157743257 POU domain, class 6, transcription factor 2 [Homo
sapiens]
Length = 691
Score = 110 bits (274), Expect = 3e-24
Identities = 97/349 (27%), Positives = 156/349 (44%), Gaps = 56/349 (16%)
Query: 37 NGLDFNRQIKTEDLSDSLQQTLSHRPCHLSQGPAMMSGNQMSGLNASPCQDMASLHPLQQ 96
N L + + + ++++ Q + P + GP+ + + GL P + Q
Sbjct: 323 NALSSLQGVTGQLVTNAQGQIIGTIPLMPNPGPSSQAASGTQGLQVQPITPQLLTNAQGQ 382
Query: 97 LVL-VPGH----LQSVSQFLLSQTQPGQQGLQPNLLPFPQQQSGLLLPQTGPGLASQAFG 151
++ V G+ + + LS +PGQQ QP+ Q S L AS +
Sbjct: 383 IIATVIGNQILPVINTQGITLSPIKPGQQLHQPSQTSVGQAASQGNLLHLAHSQASMSQS 442
Query: 152 HPGLPGSSLEPHLEASQHLPVPKHLPS---SGGADEPSDLEELEKFAKTFKQRRIKLGFT 208
P SS +S L V + + + + G + +LEE+ +FAK FK RR+ LG T
Sbjct: 443 -PVRQASSSSSSSSSSSALSVGQLVSNPQTAAGEVDGVNLEEIREFAKAFKIRRLSLGLT 501
Query: 209 QGDVGLAMGKLYGNDFSQTTI------------------------------------SRF 232
Q VG A+ G +SQ+ I +RF
Sbjct: 502 QTQVGQALSATEGPAYSQSAICRHTILRSHFFLPQEAQENTIASSLTAKLNPGLLYPARF 561
Query: 233 EALNLSFKNMCKLKPLLEKWLNDAESSPSDPSVSTPSSYPSLSEVFG----RKRKKRTSI 288
E L+++ K+ K+KP+LE+W+ +AE+ + +L+E G +KRK+RTS
Sbjct: 562 EKLDITPKSAQKIKPVLERWMAEAEARHR-------AGMQNLTEFIGSEPSKKRKRRTSF 614
Query: 289 ETNIRLTLEKRFQDNPKPSSEEISMIAEQLSMEKEVVRVWFCNRRQKEK 337
L F+ N PS +E++ IAE+L+ ++EVVRVWFCN+RQ K
Sbjct: 615 TPQALEILNAHFEKNTHPSGQEMTEIAEKLNYDREVVRVWFCNKRQALK 663
>gi|149588930 gastrulation brain homeo box 1 [Homo sapiens]
Length = 363
Score = 58.2 bits (139), Expect = 1e-08
Identities = 74/288 (25%), Positives = 106/288 (36%), Gaps = 20/288 (6%)
Query: 83 SPCQDMASLHPLQQLVLVPGHLQSVSQFLLSQTQPGQQGLQPNLLPFPQQQSGLLLPQ-- 140
+P A L PL L G L + L Q P L L F + PQ
Sbjct: 62 APAPLPAGLPPLAPLASFAGRLTNTFCAGLGQAVPSMVALTTALPSFAEPPDAFYGPQEL 121
Query: 141 ---TGPGLASQAFGHPGLPGSSLEPHLEASQHLPVPKHLPSSGGADEPSDLE---ELEKF 194
A+ A +P G E LEA + LP + + P E L
Sbjct: 122 AAAAAAAAATAARNNPEPGGRRPEGGLEADELLPAREKVAEPPPPPPPHFSETFPSLPAE 181
Query: 195 AKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLN 254
K + KL + GD + + G+ ++ + KP L+ L
Sbjct: 182 GKVYSSDEEKLEASAGDPAGSEQEEEGSGGDSEDDGFLDSSAGGPGALLGPKPKLKGSLG 241
Query: 255 DA--ESSPSDPSVSTPSSYPSLSEVFGRKRKKRTSIETNIRLTLEKRFQDNPKPSSEEIS 312
E +P V+ P G+ R++RT+ + L LEK F S E S
Sbjct: 242 TGAEEGAPVTAGVTAPG---------GKSRRRRTAFTSEQLLELEKEFHCKKYLSLTERS 292
Query: 313 MIAEQLSMEKEVVRVWFCNRRQKEKRINC-PVATPIKPPVYNSRLVSP 359
IA L + + V++WF NRR K KRI V++ PV N ++V P
Sbjct: 293 QIAHALKLSEVQVKIWFQNRRAKWKRIKAGNVSSRSGEPVRNPKIVVP 340
>gi|126090663 zinc finger homeodomain 4 [Homo sapiens]
Length = 3571
Score = 50.1 bits (118), Expect = 4e-06
Identities = 33/93 (35%), Positives = 49/93 (52%), Gaps = 4/93 (4%)
Query: 258 SSPSDPSVSTP--SSYPSLSEVFGRKRKKRTSIE-TNIRLTLEKR-FQDNPKPSSEEISM 313
SS +DPS P SS P S+ R KR + +N++L + K F D P+ +E M
Sbjct: 2857 SSIADPSSPNPFGSSNPFKSKSNDRPGHKRFRTQMSNLQLKVLKACFSDYRTPTMQECEM 2916
Query: 314 IAEQLSMEKEVVRVWFCNRRQKEKRINCPVATP 346
+ ++ + K VV+VWF N R KEK+ + P
Sbjct: 2917 LGNEIGLPKRVVQVWFQNARAKEKKFKINIGKP 2949
Score = 39.3 bits (90), Expect = 0.007
Identities = 26/86 (30%), Positives = 36/86 (41%), Gaps = 5/86 (5%)
Query: 253 LNDAESSPSDPSVSTPSSYPSLSEVFGRKRKKRTSIETNIRLTLEKRFQDNPKPSSEEIS 312
L D P S+ S S S KR RT L+ F N P +EI
Sbjct: 2158 LEDIRIDPQPTSLEHYKSDASFS-----KRSSRTRFTDYQLRVLQDFFDTNAYPKDDEIE 2212
Query: 313 MIAEQLSMEKEVVRVWFCNRRQKEKR 338
++ L++ V+ VWF N RQK ++
Sbjct: 2213 QLSTVLNLPTRVIVVWFQNARQKARK 2238
Score = 37.0 bits (84), Expect = 0.035
Identities = 19/59 (32%), Positives = 32/59 (54%)
Query: 282 RKKRTSIETNIRLTLEKRFQDNPKPSSEEISMIAEQLSMEKEVVRVWFCNRRQKEKRIN 340
++ RT I + L F N PS E+I +AE+ + ++V++ WF N KE++ N
Sbjct: 2085 KRPRTRITDDQLKILRAYFDINNSPSEEQIQEMAEKSGLSQKVIKHWFRNTLFKERQRN 2143
>gi|31377777 NK2 homeobox 8 [Homo sapiens]
Length = 239
Score = 49.7 bits (117), Expect = 5e-06
Identities = 37/114 (32%), Positives = 54/114 (47%), Gaps = 2/114 (1%)
Query: 257 ESSPSDPSVSTPSSYPSLSEVFGRKRKKRTSIETNIR-LTLEKRFQDNPKPSSEEISMIA 315
E+SP D S PS+ P+ KRKKR + + + L LE+RF+ S+ E +A
Sbjct: 60 ETSPPDSS-QRPSARPASPGSDAEKRKKRRVLFSKAQTLELERRFRQQRYLSAPEREQLA 118
Query: 316 EQLSMEKEVVRVWFCNRRQKEKRINCPVATPIKPPVYNSRLVSPSGSLGPLSVP 369
L + V++WF N R K KR P A ++ L + G L + VP
Sbjct: 119 SLLRLTPTQVKIWFQNHRYKLKRARAPGAAESPDLAASAELHAAPGLLRRVVVP 172
>gi|45593144 gastrulation brain homeo box 2 [Homo sapiens]
Length = 348
Score = 48.9 bits (115), Expect = 9e-06
Identities = 67/260 (25%), Positives = 100/260 (38%), Gaps = 19/260 (7%)
Query: 119 QQGLQPNLLPFPQQQSGLLLP-----QTGPGLASQAFGHPGLPG--SSLEPHLEASQHLP 171
Q LQP L P LP G+A + LPG S+ H EA+
Sbjct: 67 QAALQPALPPAHPHHQIPSLPTGFCSSLAQGMALTSTLMATLPGGFSASPQHQEAAAARK 126
Query: 172 -VPKHLPSSGGADEPSDLEELEKFAKTFKQRRIKL-GFTQGDVGLA--MGKLYGNDFSQT 227
P+ LP G D+ L+ + K F + L F+ + A +G + G ++
Sbjct: 127 FAPQPLPGGGNFDKAEALQADAEDGKGFLAKEGSLLAFSAAETVQASLVGAVRGQGKDES 186
Query: 228 TIS-----RFEALNLSFKNMCKLKPLLEKWLNDAESSPSDPSVSTPSSYPSLSEVF--GR 280
+ + E+ +L L E P TP S + G+
Sbjct: 187 KVEDDPKGKEESFSLESDVDYSSDDNLTGQAAHKEEDPGHALEETPPSSGAAGSTTSTGK 246
Query: 281 KRKKRTSIETNIRLTLEKRFQDNPKPSSEEISMIAEQLSMEKEVVRVWFCNRRQKEKRIN 340
R++RT+ + L LEK F S E S IA L + + V++WF NRR K KR+
Sbjct: 247 NRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEVQVKIWFQNRRAKWKRVK 306
Query: 341 CPVA-TPIKPPVYNSRLVSP 359
A + P N ++V P
Sbjct: 307 AGNANSKTGEPSRNPKIVVP 326
>gi|63054872 ladybird homeobox 1 [Homo sapiens]
Length = 281
Score = 48.1 bits (113), Expect = 2e-05
Identities = 41/150 (27%), Positives = 62/150 (41%), Gaps = 15/150 (10%)
Query: 280 RKRKKRTSIETNIRLTLEKRFQDNPKPSSEEISMIAEQLSMEKEVVRVWFCNRRQKEKRI 339
++RK RT+ + LEKRF S + IA+QL + V WF NRR K KR
Sbjct: 124 KRRKSRTAFTNHQIYELEKRFLYQKYLSPADRDQIAQQLGLTNAQVITWFQNRRAKLKR- 182
Query: 340 NCPVATPIKPPVYNSRLVSPSGSLGPLSVPPVHSTMPGTVTSSCSPGN-NSRPSS----- 393
+K V +++ + PSG + +++ + T G SRP S
Sbjct: 183 ---DLEEMKADVESAKKLGPSGQMDIVALAELEQNSEATAGGGGGCGRAKSRPGSPVLPP 239
Query: 394 -----PGSGLHASSPTASQNNSKAAVNSAS 418
PG+G SP + + A+ S
Sbjct: 240 GAPKAPGAGALQLSPASPLTDQPASSQDCS 269
>gi|11641283 LIM homeobox protein 5 [Homo sapiens]
Length = 402
Score = 47.0 bits (110), Expect = 3e-05
Identities = 31/98 (31%), Positives = 50/98 (51%), Gaps = 3/98 (3%)
Query: 245 LKPLLEKWLND--AESSPSDPSVSTPSSYPSLSEVFGRKRK-KRTSIETNIRLTLEKRFQ 301
L P L+ L D E+ S S ++ + + G KR+ RT+I+ TL+ F
Sbjct: 141 LSPDLQDALQDDPKETDNSTSSDKETANNENEEQNSGTKRRGPRTTIKAKQLETLKAAFA 200
Query: 302 DNPKPSSEEISMIAEQLSMEKEVVRVWFCNRRQKEKRI 339
PKP+ +A++ + V++VWF NRR KE+R+
Sbjct: 201 ATPKPTRHIREQLAQETGLNMRVIQVWFQNRRSKERRM 238
>gi|15375314 LIM homeobox protein 4 [Homo sapiens]
Length = 390
Score = 46.6 bits (109), Expect = 4e-05
Identities = 20/58 (34%), Positives = 36/58 (62%)
Query: 282 RKKRTSIETNIRLTLEKRFQDNPKPSSEEISMIAEQLSMEKEVVRVWFCNRRQKEKRI 339
++ RT+I TL+ ++++PKP+ ++ + ++ VV+VWF NRR KEKR+
Sbjct: 158 KRPRTTITAKQLETLKNAYKNSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRL 215
>gi|30410785 LIM homeobox protein 1 [Homo sapiens]
Length = 406
Score = 46.6 bits (109), Expect = 4e-05
Identities = 31/102 (30%), Positives = 46/102 (45%), Gaps = 23/102 (22%)
Query: 261 SDPSVSTPSSYPSLSEV----------------------FGRKRK-KRTSIETNIRLTLE 297
SDPS+S S PS + G KR+ RT+I+ TL+
Sbjct: 137 SDPSLSPDSQDPSQDDAKDSESANVSDKEAGSNENDDQNLGAKRRGPRTTIKAKQLETLK 196
Query: 298 KRFQDNPKPSSEEISMIAEQLSMEKEVVRVWFCNRRQKEKRI 339
F PKP+ +A++ + V++VWF NRR KE+R+
Sbjct: 197 AAFAATPKPTRHIREQLAQETGLNMRVIQVWFQNRRSKERRM 238
>gi|116517292 cut-like 2 [Homo sapiens]
Length = 1486
Score = 46.2 bits (108), Expect = 6e-05
Identities = 39/142 (27%), Positives = 64/142 (45%), Gaps = 15/142 (10%)
Query: 254 NDAESSPSDPSVSTPSSYP---SLSEVFGRKRKKRTSIETNIRLTLEKRFQDNPKPSSEE 310
+D+ES + +P P SL ++ +K R + + L K +Q P PS +
Sbjct: 1142 SDSESPATRSECPSPCLQPQDLSLLQI----KKPRVVLAPEEKEALRKAYQLEPYPSQQT 1197
Query: 311 ISMIAEQLSMEKEVVRVWFCNRRQKEKRINCPVATPIKPPVYNSRLVSPSGSLGPLSVPP 370
I +++ QL+++ V WF N R + +R T +P + PSG GP +PP
Sbjct: 1198 IELLSFQLNLKTNTVINWFHNYRSRMRREMLVEGTQDEPD------LDPSG--GPGILPP 1249
Query: 371 VHSTMPGTVTSSCSPGNNSRPS 392
HS T S S + +P+
Sbjct: 1250 GHSHPDPTPQSPDSETEDQKPT 1271
>gi|24497589 aristaless related homeobox [Homo sapiens]
Length = 562
Score = 46.2 bits (108), Expect = 6e-05
Identities = 43/156 (27%), Positives = 66/156 (42%), Gaps = 9/156 (5%)
Query: 255 DAESSPSDPSVSTPSSYPSLSEVFGRKRKKRTSIETNIRLT-LEKRFQDNPKPSSEEISM 313
DAE + SV + S + RK+++ + T+ +L LE+ FQ P
Sbjct: 301 DAEGKDGEDSVCLSAGSDSEEGLLKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTREE 360
Query: 314 IAEQLSMEKEVVRVWFCNRRQK-EKRINC-----PVATPIKPPVYNSRLVSPSGSLGPLS 367
+A +L + + V+VWF NRR K KR P P P+ + +SP P
Sbjct: 361 LAMRLDLTEARVQVWFQNRRAKWRKREKAGAQTHPPGLPFPGPLSATHPLSPYLDASPF- 419
Query: 368 VPPVHSTMPGTVTSSCSPGNNSRPSSPGSGLHASSP 403
PP H + T++ + + PS P AS P
Sbjct: 420 -PPHHPALDSAWTAAAAAAAAAFPSLPPPPGSASLP 454
>gi|4758090 NK2 transcription factor related, locus 5 [Homo sapiens]
Length = 324
Score = 45.8 bits (107), Expect = 8e-05
Identities = 42/156 (26%), Positives = 65/156 (41%), Gaps = 26/156 (16%)
Query: 280 RKRKKRTSIETNIRLTLEKRFQDNPKPSSEEISMIAEQLSMEKEVVRVWFCNRRQKEKR- 338
R+RK R LE+RF+ S+ E +A L + V++WF NRR K KR
Sbjct: 137 RRRKPRVLFSQAQVYELERRFKQQRYLSAPERDQLASVLKLTSTQVKIWFQNRRYKCKRQ 196
Query: 339 --------INCP---------VATPI-----KPPVYNSRLVSPSGSLG--PLSVPPVHST 374
+ P +A P+ KP + +S +P+ +G P +
Sbjct: 197 RQDQTLELVGLPPPPPPPARRIAVPVLVRDGKPCLGDSAPYAPAYGVGLNPYGY-NAYPA 255
Query: 375 MPGTVTSSCSPGNNSRPSSPGSGLHASSPTASQNNS 410
PG ++CSPG + + P A TA+ NN+
Sbjct: 256 YPGYGGAACSPGYSCTAAYPAGPSPAQPATAAANNN 291
>gi|121114296 caudal type homeobox 1 [Homo sapiens]
Length = 265
Score = 45.8 bits (107), Expect = 8e-05
Identities = 36/123 (29%), Positives = 56/123 (45%), Gaps = 15/123 (12%)
Query: 259 SPSDPSVSTPSSYPSLSEVF-----GRKRKKRTSIETNI------RLTLEKRFQDNPKPS 307
+PS P P+ Y + G K RT + + RL LEK F + +
Sbjct: 121 TPSSPGAQRPTPYEWMRRSVAAGGGGGSGKTRTKDKYRVVYTDHQRLELEKEFHYSRYIT 180
Query: 308 SEEISMIAEQLSMEKEVVRVWFCNRRQKEKRIN---CPVATPIKPPVYNSRLVSPSG-SL 363
S +A L + + V++WF NRR KE+++N P +PP+ + +P+G SL
Sbjct: 181 IRRKSELAANLGLTERQVKIWFQNRRAKERKVNKKKQQQQQPPQPPMAHDITATPAGPSL 240
Query: 364 GPL 366
G L
Sbjct: 241 GGL 243
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.127 0.372
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,368,331
Number of Sequences: 37866
Number of extensions: 1051410
Number of successful extensions: 5623
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 276
Number of HSP's successfully gapped in prelim test: 238
Number of HSP's that attempted gapping in prelim test: 4765
Number of HSP's gapped (non-prelim): 1127
length of query: 436
length of database: 18,247,518
effective HSP length: 105
effective length of query: 331
effective length of database: 14,271,588
effective search space: 4723895628
effective search space used: 4723895628
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.