BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|148596953 ankyrin repeat and IBR domain containing 1 [Homo sapiens] (1089 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|148596953 ankyrin repeat and IBR domain containing 1 [Homo sa... 2247 0.0 gi|5453557 ariadne homolog 2 [Homo sapiens] 210 5e-54 gi|187761373 ariadne ubiquitin-conjugating enzyme E2 binding pro... 196 1e-49 gi|24307991 p53-associated parkin-like cytoplasmic protein [Homo... 136 1e-31 gi|35493801 ring finger protein 19 [Homo sapiens] 95 3e-19 gi|35493782 ring finger protein 19 [Homo sapiens] 95 3e-19 gi|34577102 ring finger protein 14 isoform 1 [Homo sapiens] 94 9e-19 gi|34577100 ring finger protein 14 isoform 1 [Homo sapiens] 94 9e-19 gi|34577098 ring finger protein 14 isoform 1 [Homo sapiens] 94 9e-19 gi|34577096 ring finger protein 14 isoform 2 [Homo sapiens] 94 9e-19 gi|4757762 ring finger protein 14 isoform 1 [Homo sapiens] 94 9e-19 gi|188219579 ring finger protein 19B isoform b [Homo sapiens] 93 1e-18 gi|188219577 ring finger protein 19B isoform a [Homo sapiens] 92 2e-18 gi|38045938 ring finger protein 144 [Homo sapiens] 80 8e-15 gi|50284696 IBR domain containing 2 [Homo sapiens] 79 2e-14 gi|22749145 ring finger protein 217 [Homo sapiens] 65 3e-10 gi|169790973 parkin isoform 3 [Homo sapiens] 64 6e-10 gi|169790971 parkin isoform 2 [Homo sapiens] 64 6e-10 gi|169790969 parkin isoform 1 [Homo sapiens] 64 6e-10 gi|116063534 ankyrin repeat domain 27 (VPS9 domain) [Homo sapiens] 63 1e-09 gi|5454168 RanBP-type and C3HC4-type zinc finger containing 1 is... 54 6e-07 gi|144953898 RanBP-type and C3HC4-type zinc finger containing 1 ... 54 6e-07 gi|24586688 ankyrin repeat and SOCS box-containing protein 16 [H... 53 2e-06 gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens] 52 2e-06 gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens] 52 2e-06 gi|4506217 proteasome 26S non-ATPase subunit 10 isoform 1 [Homo ... 52 4e-06 gi|215598574 ankyrin 1 isoform 9 [Homo sapiens] 51 5e-06 gi|70780359 ankyrin 1 isoform 1 [Homo sapiens] 51 5e-06 gi|70780357 ankyrin 1 isoform 3 [Homo sapiens] 51 5e-06 gi|70780355 ankyrin 1 isoform 2 [Homo sapiens] 51 5e-06 >gi|148596953 ankyrin repeat and IBR domain containing 1 [Homo sapiens] Length = 1089 Score = 2247 bits (5822), Expect = 0.0 Identities = 1089/1089 (100%), Positives = 1089/1089 (100%) Query: 1 MGNTTTKFRKALINGDENLACQIYENNPQLKESLDPNTSYGEPYQHNTPLHYAARHGMNK 60 MGNTTTKFRKALINGDENLACQIYENNPQLKESLDPNTSYGEPYQHNTPLHYAARHGMNK Sbjct: 1 MGNTTTKFRKALINGDENLACQIYENNPQLKESLDPNTSYGEPYQHNTPLHYAARHGMNK 60 Query: 61 ILGTFLGRDGNPNKRNVHNETSMHLLCMGPQIMISEGALHPRLARPTEDDFRRADCLQMI 120 ILGTFLGRDGNPNKRNVHNETSMHLLCMGPQIMISEGALHPRLARPTEDDFRRADCLQMI Sbjct: 61 ILGTFLGRDGNPNKRNVHNETSMHLLCMGPQIMISEGALHPRLARPTEDDFRRADCLQMI 120 Query: 121 LKWKGAKLDQGEYERAAIDAVDNKKNTPLHYAAASGMKACVELLVKHGGDLFAENENKDT 180 LKWKGAKLDQGEYERAAIDAVDNKKNTPLHYAAASGMKACVELLVKHGGDLFAENENKDT Sbjct: 121 LKWKGAKLDQGEYERAAIDAVDNKKNTPLHYAAASGMKACVELLVKHGGDLFAENENKDT 180 Query: 181 PCDCAEKQHHKDLALNLESQMVFSRDPEAEEIEAEYAALDKREPYEGLRPQDLRRLKDML 240 PCDCAEKQHHKDLALNLESQMVFSRDPEAEEIEAEYAALDKREPYEGLRPQDLRRLKDML Sbjct: 181 PCDCAEKQHHKDLALNLESQMVFSRDPEAEEIEAEYAALDKREPYEGLRPQDLRRLKDML 240 Query: 241 IVETADMLQAPLFTAEALLRAHDWDREKLLEAWMSNPENCCQRSGVQMPTPPPSGYNAWD 300 IVETADMLQAPLFTAEALLRAHDWDREKLLEAWMSNPENCCQRSGVQMPTPPPSGYNAWD Sbjct: 241 IVETADMLQAPLFTAEALLRAHDWDREKLLEAWMSNPENCCQRSGVQMPTPPPSGYNAWD 300 Query: 301 TLPSPRTPRTTRSSVTSPDEISLSPGDLDTSLCDICMCSISVFEDPVDMPCGHDFCRGCW 360 TLPSPRTPRTTRSSVTSPDEISLSPGDLDTSLCDICMCSISVFEDPVDMPCGHDFCRGCW Sbjct: 301 TLPSPRTPRTTRSSVTSPDEISLSPGDLDTSLCDICMCSISVFEDPVDMPCGHDFCRGCW 360 Query: 361 ESFLNLKIQEGEAHNIFCPAYDCFQLVPVDIIESVVSKEMDKRYLQFDIKAFVENNPAIK 420 ESFLNLKIQEGEAHNIFCPAYDCFQLVPVDIIESVVSKEMDKRYLQFDIKAFVENNPAIK Sbjct: 361 ESFLNLKIQEGEAHNIFCPAYDCFQLVPVDIIESVVSKEMDKRYLQFDIKAFVENNPAIK 420 Query: 421 WCPTPGCDRAVRLTKQGSNTSGSDTLSFPLLRAPAVDCGKGHLFCWECLGEAHEPCDCQT 480 WCPTPGCDRAVRLTKQGSNTSGSDTLSFPLLRAPAVDCGKGHLFCWECLGEAHEPCDCQT Sbjct: 421 WCPTPGCDRAVRLTKQGSNTSGSDTLSFPLLRAPAVDCGKGHLFCWECLGEAHEPCDCQT 480 Query: 481 WKNWLQKITEMKPEELVGVSEAYEDAANCLWLLTNSKPCANCKSPIQKNEGCNHMQCAKC 540 WKNWLQKITEMKPEELVGVSEAYEDAANCLWLLTNSKPCANCKSPIQKNEGCNHMQCAKC Sbjct: 481 WKNWLQKITEMKPEELVGVSEAYEDAANCLWLLTNSKPCANCKSPIQKNEGCNHMQCAKC 540 Query: 541 KYDFCWICLEEWKKHSSSTGGYYRCTRYEVIQHVEEQSKEMTVEAEKKHKRFQELDRFMH 600 KYDFCWICLEEWKKHSSSTGGYYRCTRYEVIQHVEEQSKEMTVEAEKKHKRFQELDRFMH Sbjct: 541 KYDFCWICLEEWKKHSSSTGGYYRCTRYEVIQHVEEQSKEMTVEAEKKHKRFQELDRFMH 600 Query: 601 YYTRFKNHEHSYQLEQRLLKTAKEKMEQLSRALKETEGGCPDTTFIEDAVHVLLKTRRIL 660 YYTRFKNHEHSYQLEQRLLKTAKEKMEQLSRALKETEGGCPDTTFIEDAVHVLLKTRRIL Sbjct: 601 YYTRFKNHEHSYQLEQRLLKTAKEKMEQLSRALKETEGGCPDTTFIEDAVHVLLKTRRIL 660 Query: 661 KCSYPYGFFLEPKSTKKEIFELMQTDLEMVTEDLAQKVNRPYLRTPRHKIIKAACLVQQK 720 KCSYPYGFFLEPKSTKKEIFELMQTDLEMVTEDLAQKVNRPYLRTPRHKIIKAACLVQQK Sbjct: 661 KCSYPYGFFLEPKSTKKEIFELMQTDLEMVTEDLAQKVNRPYLRTPRHKIIKAACLVQQK 720 Query: 721 RQEFLASVARGVAPADSPEAPRRSFAGGTWDWEYLGFASPEEYAEFQYRRRHRQRRRGDV 780 RQEFLASVARGVAPADSPEAPRRSFAGGTWDWEYLGFASPEEYAEFQYRRRHRQRRRGDV Sbjct: 721 RQEFLASVARGVAPADSPEAPRRSFAGGTWDWEYLGFASPEEYAEFQYRRRHRQRRRGDV 780 Query: 781 HSLLSNPPDPDEPSESTLDIPEGGSSSRRPGTSVVSSASMSVLHSSSLRDYTPASRSENQ 840 HSLLSNPPDPDEPSESTLDIPEGGSSSRRPGTSVVSSASMSVLHSSSLRDYTPASRSENQ Sbjct: 781 HSLLSNPPDPDEPSESTLDIPEGGSSSRRPGTSVVSSASMSVLHSSSLRDYTPASRSENQ 840 Query: 841 DSLQALSSLDEDDPNILLAIQLSLQESGLALDEETRDFLSNEASLGAIGTSLPSRLDSVP 900 DSLQALSSLDEDDPNILLAIQLSLQESGLALDEETRDFLSNEASLGAIGTSLPSRLDSVP Sbjct: 841 DSLQALSSLDEDDPNILLAIQLSLQESGLALDEETRDFLSNEASLGAIGTSLPSRLDSVP 900 Query: 901 RNTDSPRAALSSSELLELGDSLMRLGAENDPFSTDTLSSHPLSEARSDFCPSSSDPDSAG 960 RNTDSPRAALSSSELLELGDSLMRLGAENDPFSTDTLSSHPLSEARSDFCPSSSDPDSAG Sbjct: 901 RNTDSPRAALSSSELLELGDSLMRLGAENDPFSTDTLSSHPLSEARSDFCPSSSDPDSAG 960 Query: 961 QDPNINDNLLGNIMAWFHDMNPQSIALIPPATTEISADSQLPCIKDGSEGVKDVELVLPE 1020 QDPNINDNLLGNIMAWFHDMNPQSIALIPPATTEISADSQLPCIKDGSEGVKDVELVLPE Sbjct: 961 QDPNINDNLLGNIMAWFHDMNPQSIALIPPATTEISADSQLPCIKDGSEGVKDVELVLPE 1020 Query: 1021 DSMFEDASVSEGRGTQIEENPLEENILAGEAASQAGDSGNEAANRGDGSDVSSQTPQTSS 1080 DSMFEDASVSEGRGTQIEENPLEENILAGEAASQAGDSGNEAANRGDGSDVSSQTPQTSS Sbjct: 1021 DSMFEDASVSEGRGTQIEENPLEENILAGEAASQAGDSGNEAANRGDGSDVSSQTPQTSS 1080 Query: 1081 DWLEQVHLV 1089 DWLEQVHLV Sbjct: 1081 DWLEQVHLV 1089 >gi|5453557 ariadne homolog 2 [Homo sapiens] Length = 493 Score = 210 bits (535), Expect = 5e-54 Identities = 141/529 (26%), Positives = 245/529 (46%), Gaps = 92/529 (17%) Query: 174 ENENKDTPCDCAEKQHHKDLALNLESQMVFSRDPEAEEIEAEYAALDKREPYEGLRPQDL 233 E E +D P D + ++ +A ++E Q + DPE E ++ L +E EG + + Sbjct: 25 EEEEEDDPGDIED--YYVGVASDVEQQGADAFDPE----EYQFTCLTYKES-EGALNEHM 77 Query: 234 RRLKDMLIVETADMLQAPLFTAEALLRAHDWDREKLLEAWMSNPENCCQRSGVQMPTPPP 293 L +L V + A+ +L W ++L+ + SN + VQ P P Sbjct: 78 TSLASVLKVSHS--------VAKLILVNFHWQVSEILDRYKSNSAQLLVEARVQ---PNP 126 Query: 294 SGYNAWDTLPSPRTPRTTRSSVTSPDEISLSPGDLDTSLCDICMCSISVFEDPVDMPCGH 353 S + +P+ P C +CM + E+ + + C H Sbjct: 127 SKH-----VPTSHPPHH----------------------CAVCMQFVRK-ENLLSLACQH 158 Query: 354 DFCRGCWESFLNLKIQEGEAHNIFCPAYDCFQLVPVDIIESVV-SKEMDKRYLQFDIKAF 412 FCR CWE ++ +++G + C A DC P D + ++ ++E+ ++Y ++ + + Sbjct: 159 QFCRSCWEQHCSVLVKDGVGVGVSCMAQDCPLRTPEDFVFPLLPNEELREKYRRYLFRDY 218 Query: 413 VENNPAIKWCPTPGCDRAVRLTKQGSNTSGSDTLSFPLLRAPAVDCGK-GHLFCWECLGE 471 VE++ ++ CP C +R+ + RA V C + +FC++C Sbjct: 219 VESHYQLQLCPGADCPMVIRVQEP---------------RARRVQCNRCNEVFCFKCRQM 263 Query: 472 AHEPCDCQTWKNWLQKITEMKPEELVGVSEAYEDAANCLWLLTNSKPCANCKSPIQKNEG 531 H P DC T + WL K + D+ ++ ++K C C I+KN G Sbjct: 264 YHAPTDCATIRKWLTKCAD--------------DSETANYISAHTKDCPKCNICIEKNGG 309 Query: 532 CNHMQCAKCKYDFCWICLEEWKKHSSSTGGYYRCTRYEVIQHVEEQSKEMTVEAEKKHKR 591 CNHMQC+KCK+DFCW+CL +WK H S YY C+RY+ + QS++ Sbjct: 310 CNHMQCSKCKHDFCWMCLGDWKTHGSE---YYECSRYKENPDIVNQSQQAQAR------- 359 Query: 592 FQELDRFMHYYTRFKNHEHSYQLEQRLLKTAKEKMEQLSRALKETEGGCPDTTFIEDAVH 651 + L +++ Y+ R++NH S QLE + + EK+++ + G D ++++A Sbjct: 360 -EALKKYLFYFERWENHNKSLQLEAQTYQRIHEKIQE---RVMNNLGTWIDWQYLQNAAK 415 Query: 652 VLLKTRRILKCSYPYGFFLEPKSTKKEIFELMQTDLEMVTEDLAQKVNR 700 +L K R L+ +YPY +++E +K++FE Q LE E+L+ KV R Sbjct: 416 LLAKCRYTLQYTYPYAYYME-SGPRKKLFEYQQAQLEAEIENLSWKVER 463 >gi|187761373 ariadne ubiquitin-conjugating enzyme E2 binding protein homolog 1 [Homo sapiens] Length = 557 Score = 196 bits (498), Expect = 1e-49 Identities = 145/518 (27%), Positives = 225/518 (43%), Gaps = 83/518 (16%) Query: 225 YEGLRPQDLRRLKDMLIVETADMLQAPLFTAEALLRAHDWDREKLLEAWMS-NPENCCQR 283 YE L + + + I E +++Q P LL +WD+EKL+E + N E Sbjct: 101 YEVLTAEQILQHMVECIREVNEVIQNPATITRILLSHFNWDKEKLMERYFDGNLEKLFAE 160 Query: 284 SGVQMPTPPPSGYNAWDTLPSPRTPRTTRSSVTSPDEISLSPGDLDTSLCDICMCSI--S 341 V P+ S TRSS C IC + S Sbjct: 161 CHVINPSKK-----------SRTRQMNTRSSAQDMP-------------CQICYLNYPNS 196 Query: 342 VFEDPVDMPCGHDFCRGCWESFLNLKI-QEGEAHNIFCPAYDCFQLVPVDIIESVVSKEM 400 F + CGH FC CW +L KI +EG I CPA+ C LV + + +++ Sbjct: 197 YF---TGLECGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHGCDILVDDNTVMRLITDSK 253 Query: 401 DK-RYLQFDIKAFVENNPAIKWCPTPGCDRAVRLTKQGSNTSGSDTLSFPLLRAPAVDCG 459 K +Y +FVE N +KWCP P C V++ +P A V C Sbjct: 254 VKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKV-------------QYP--DAKPVRCK 298 Query: 460 KGHLFCWECLGEAHEPCDCQTWKNWLQKITEMKPEELVGVSEAYEDAANCLWLLTNSKPC 519 G FC+ C H+P C+ K W++K + D+ W+ N+K C Sbjct: 299 CGRQFCFNCGENWHDPVKCKWLKKWIKKCDD--------------DSETSNWIAANTKEC 344 Query: 520 ANCKSPIQKNEGCNHMQC--AKCKYDFCWICLEEWKKHSSSTGGYYRCTRYEVIQHVEEQ 577 C I+K+ GCNHM C CK +FCW+CL W+ H S+ +Y C RY E Sbjct: 345 PKCHVTIEKDGGCNHMVCRNQNCKAEFCWVCLGPWEPHGSA---WYNCNRY------NED 395 Query: 578 SKEMTVEAEKKHKRFQELDRFMHYYTRFKNHEHSYQLEQRLLKTAKEKMEQLSRALKETE 637 + +A+++ + L R++ Y R+ NH S + E +L K+KME+ +++ Sbjct: 396 DAKAARDAQERSR--AALQRYLFYCNRYMNHMQSLRFEHKLYAQVKQKMEE----MQQHN 449 Query: 638 GGCPDTTFIEDAVHVLLKTRRILKCSYPYGFFLEPKSTKKEIFELMQTDLEMVTEDLA-- 695 + F++ AV VL + R L +Y + F+L+ K+ + IFE Q DLE TE L+ Sbjct: 450 MSWIEVQFLKKAVDVLCQCRATLMYTYVFAFYLK-KNNQSIIFENNQADLENATEVLSGY 508 Query: 696 --QKVNRPYLRTPRHKIIKAACLVQQKRQEFLASVARG 731 + +++ L+ + K+ + +R+ L V G Sbjct: 509 LERDISQDSLQDIKQKVQDKYRYCESRRRVLLQHVHEG 546 >gi|24307991 p53-associated parkin-like cytoplasmic protein [Homo sapiens] Length = 2517 Score = 136 bits (342), Expect = 1e-31 Identities = 117/497 (23%), Positives = 200/497 (40%), Gaps = 96/497 (19%) Query: 228 LRPQDLRRLKDMLIVETADMLQAPLFTAEALLRAHDWDREKLLEAWMSNPENCCQRSGVQ 287 + PQ++ L + + + L A+ LL W E+LL+++ +PE +G+ Sbjct: 1997 MSPQEVEGLMKQTVRQVQETLNLEPDVAQHLLAHSHWGAEQLLQSYSEDPEPLLLAAGLC 2056 Query: 288 MPTPPPSGYNAWDTLPSPRTPRTTRSSVTSPDEISLSPGDLDTSLCDICMCSISVFEDPV 347 + ++ PD C +C+ + +D Sbjct: 2057 V--------------------HQAQAVPVRPDH------------CPVCVSPLGCDDDLP 2084 Query: 348 DMPCGHDFCRGCWESFLNLKIQEGEAHNIFCPAYDCFQLVPVDIIESVVSK-EMDKRYLQ 406 + C H C+ CW +L +I++ N CP DC I ++VS E+ +Y + Sbjct: 2085 SLCCMHYCCKSCWNEYLTTRIEQNLVLNCTCPIADCPAQPTGAFIRAIVSSPEVISKYEK 2144 Query: 407 FDIKAFVENNPAIKWCPTP-GCDRAVRLTKQGSNTSGSDTLSFPLLRAPAVDCGK-GHLF 464 ++ +VE+ + WC P GCDR + G T+ C K G Sbjct: 2145 ALLRGYVESCSNLTWCTNPQGCDRILCRQGLGCGTT----------------CSKCGWAS 2188 Query: 465 CWEC-LGEAHEPCDCQTWKNWLQKITEMKPEELVGVSEAYEDAANCLWLLTNSKPCANCK 523 C+ C EAH P C W + + + + V + A + SK C +C+ Sbjct: 2189 CFNCSFPEAHYPASCGHMSQW---VDDGGYYDGMSVEAQSKHLAKLI-----SKRCPSCQ 2240 Query: 524 SPIQKNEGCNHMQCAKCKYDFCWICLEEWKKHSSSTGGYYRCTRYEVIQHVEEQSKEMTV 583 +PI+KNEGC HM CAKC + FCW CL+ WK + YY C+ M Sbjct: 2241 APIEKNEGCLHMTCAKCNHGFCWRCLKSWKPNHKD---YYNCS-------------AMVS 2284 Query: 584 EAEKKHKRFQELDRFMHYYTRFKNHEHSYQLEQRLLKTAKEKMEQLSRALKETEGGCPDT 643 +A ++ KRFQ+ + ++ + + E + L R+ A+ E Sbjct: 2285 KAARQEKRFQDYNERCTFHHQAR--EFAVNLRNRV------------SAIHEVPPP-RSF 2329 Query: 644 TFIEDAVHVLLKTRRILKCSYPYGFFLEPKSTKKEIFELMQTDLEMVTEDLAQKVNRPYL 703 TF+ DA L + R++L + Y F+ + + ++ E +LE+ T L + L Sbjct: 2330 TFLNDACQGLEQARKVLAYACVYSFYSQ-DAEYMDVVEQQTENLELHTNALQILLEETLL 2388 Query: 704 R----TPRHKIIKAACL 716 R ++++A CL Sbjct: 2389 RCRDLASSLRLLRADCL 2405 >gi|35493801 ring finger protein 19 [Homo sapiens] Length = 838 Score = 95.1 bits (235), Expect = 3e-19 Identities = 69/248 (27%), Positives = 107/248 (43%), Gaps = 29/248 (11%) Query: 310 TTRSSVTSPDEISLSPGDLDTSLCDICMCSISVFEDPVDMPCGHDFCRGCWESFLNLKIQ 369 T SS IS GD C +C+ S P M C H C C +L ++I Sbjct: 111 TNTSSDNGLTSISKQIGDFIE--CPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEIS 168 Query: 370 EGEAHNIFCPAYDCFQLVPVDIIESVVSKE-MDKRYLQFDIKAFVENNPAIKWCPTPGCD 428 E NI CP +C + I ++S + + ++Y +F ++ ++ +P +WCP P C Sbjct: 169 ESRV-NISCP--ECTERFNPHDIRLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCG 225 Query: 429 RAVRLTKQGSNTSGSDTLSFPLLRAPAVDCGK---GHLFCWECLGEAHEPCDCQTWKNWL 485 AV ++F P + CG+ G FC+ C H C + Sbjct: 226 YAV--------------IAFGCASCPKLTCGREGCGTEFCYHCKQIWHPNQTCDAARQER 271 Query: 486 QKITEMKPEELVGVSEAYEDAANCLWLLTNSKPCANCKSPIQK-NEG-CNHMQCAKCKYD 543 + ++ +S + E A + KPC C + I K N+G CNHM CA C + Sbjct: 272 AQSLRLRTIRSSSISYSQESGAAA----DDIKPCPRCAAYIIKMNDGSCNHMTCAVCGCE 327 Query: 544 FCWICLEE 551 FCW+C++E Sbjct: 328 FCWLCMKE 335 >gi|35493782 ring finger protein 19 [Homo sapiens] Length = 838 Score = 95.1 bits (235), Expect = 3e-19 Identities = 69/248 (27%), Positives = 107/248 (43%), Gaps = 29/248 (11%) Query: 310 TTRSSVTSPDEISLSPGDLDTSLCDICMCSISVFEDPVDMPCGHDFCRGCWESFLNLKIQ 369 T SS IS GD C +C+ S P M C H C C +L ++I Sbjct: 111 TNTSSDNGLTSISKQIGDFIE--CPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEIS 168 Query: 370 EGEAHNIFCPAYDCFQLVPVDIIESVVSKE-MDKRYLQFDIKAFVENNPAIKWCPTPGCD 428 E NI CP +C + I ++S + + ++Y +F ++ ++ +P +WCP P C Sbjct: 169 ESRV-NISCP--ECTERFNPHDIRLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCG 225 Query: 429 RAVRLTKQGSNTSGSDTLSFPLLRAPAVDCGK---GHLFCWECLGEAHEPCDCQTWKNWL 485 AV ++F P + CG+ G FC+ C H C + Sbjct: 226 YAV--------------IAFGCASCPKLTCGREGCGTEFCYHCKQIWHPNQTCDAARQER 271 Query: 486 QKITEMKPEELVGVSEAYEDAANCLWLLTNSKPCANCKSPIQK-NEG-CNHMQCAKCKYD 543 + ++ +S + E A + KPC C + I K N+G CNHM CA C + Sbjct: 272 AQSLRLRTIRSSSISYSQESGAAA----DDIKPCPRCAAYIIKMNDGSCNHMTCAVCGCE 327 Query: 544 FCWICLEE 551 FCW+C++E Sbjct: 328 FCWLCMKE 335 >gi|34577102 ring finger protein 14 isoform 1 [Homo sapiens] Length = 474 Score = 93.6 bits (231), Expect = 9e-19 Identities = 58/234 (24%), Positives = 99/234 (42%), Gaps = 34/234 (14%) Query: 332 LCDICMCSISVFEDPVDMPCGHDFCRGCWESFLNLKIQEGEAHNIFCPAYDCFQLVPVDI 391 LC IC C E + C H +C+ C + + ++I++G+ + CP C + Sbjct: 219 LCSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCPSVATPGQ 278 Query: 392 IESVVSKEMDKRYLQFDIKAFVENNPAIKWCPTPGCDRAVRLTKQGSNTSGSDTLSFPLL 451 ++ +V E+ RY + +++ ++ + +CP P C V + + G + +F Sbjct: 279 VKELVEAELFARYDRLLLQSSLDLMADVVYCPRPCCQLPV-MQEPGCTMGICSSCNFA-- 335 Query: 452 RAPAVDCGKGHLFCWECLGEAHEPCDCQTWKNWLQKITEMKPEELVG------------- 498 FC C H C K +K+ +++ E L Sbjct: 336 ------------FCTLCRLTYHGVSPC---KVTAEKLMDLRNEYLQADEANKRLLDQRYG 380 Query: 499 ---VSEAYEDAANCLWLLTNSKPCANCKSPIQKNEGCNHMQCAKCKYDFCWICL 549 + +A E+ + WL NSK C C +PI+K +GCN M C C FCWIC+ Sbjct: 381 KRVIQKALEEMESKEWLEKNSKSCPCCGTPIEKLDGCNKMTCTGCMQYFCWICM 434 >gi|34577100 ring finger protein 14 isoform 1 [Homo sapiens] Length = 474 Score = 93.6 bits (231), Expect = 9e-19 Identities = 58/234 (24%), Positives = 99/234 (42%), Gaps = 34/234 (14%) Query: 332 LCDICMCSISVFEDPVDMPCGHDFCRGCWESFLNLKIQEGEAHNIFCPAYDCFQLVPVDI 391 LC IC C E + C H +C+ C + + ++I++G+ + CP C + Sbjct: 219 LCSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCPSVATPGQ 278 Query: 392 IESVVSKEMDKRYLQFDIKAFVENNPAIKWCPTPGCDRAVRLTKQGSNTSGSDTLSFPLL 451 ++ +V E+ RY + +++ ++ + +CP P C V + + G + +F Sbjct: 279 VKELVEAELFARYDRLLLQSSLDLMADVVYCPRPCCQLPV-MQEPGCTMGICSSCNFA-- 335 Query: 452 RAPAVDCGKGHLFCWECLGEAHEPCDCQTWKNWLQKITEMKPEELVG------------- 498 FC C H C K +K+ +++ E L Sbjct: 336 ------------FCTLCRLTYHGVSPC---KVTAEKLMDLRNEYLQADEANKRLLDQRYG 380 Query: 499 ---VSEAYEDAANCLWLLTNSKPCANCKSPIQKNEGCNHMQCAKCKYDFCWICL 549 + +A E+ + WL NSK C C +PI+K +GCN M C C FCWIC+ Sbjct: 381 KRVIQKALEEMESKEWLEKNSKSCPCCGTPIEKLDGCNKMTCTGCMQYFCWICM 434 >gi|34577098 ring finger protein 14 isoform 1 [Homo sapiens] Length = 474 Score = 93.6 bits (231), Expect = 9e-19 Identities = 58/234 (24%), Positives = 99/234 (42%), Gaps = 34/234 (14%) Query: 332 LCDICMCSISVFEDPVDMPCGHDFCRGCWESFLNLKIQEGEAHNIFCPAYDCFQLVPVDI 391 LC IC C E + C H +C+ C + + ++I++G+ + CP C + Sbjct: 219 LCSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCPSVATPGQ 278 Query: 392 IESVVSKEMDKRYLQFDIKAFVENNPAIKWCPTPGCDRAVRLTKQGSNTSGSDTLSFPLL 451 ++ +V E+ RY + +++ ++ + +CP P C V + + G + +F Sbjct: 279 VKELVEAELFARYDRLLLQSSLDLMADVVYCPRPCCQLPV-MQEPGCTMGICSSCNFA-- 335 Query: 452 RAPAVDCGKGHLFCWECLGEAHEPCDCQTWKNWLQKITEMKPEELVG------------- 498 FC C H C K +K+ +++ E L Sbjct: 336 ------------FCTLCRLTYHGVSPC---KVTAEKLMDLRNEYLQADEANKRLLDQRYG 380 Query: 499 ---VSEAYEDAANCLWLLTNSKPCANCKSPIQKNEGCNHMQCAKCKYDFCWICL 549 + +A E+ + WL NSK C C +PI+K +GCN M C C FCWIC+ Sbjct: 381 KRVIQKALEEMESKEWLEKNSKSCPCCGTPIEKLDGCNKMTCTGCMQYFCWICM 434 >gi|34577096 ring finger protein 14 isoform 2 [Homo sapiens] Length = 348 Score = 93.6 bits (231), Expect = 9e-19 Identities = 58/234 (24%), Positives = 99/234 (42%), Gaps = 34/234 (14%) Query: 332 LCDICMCSISVFEDPVDMPCGHDFCRGCWESFLNLKIQEGEAHNIFCPAYDCFQLVPVDI 391 LC IC C E + C H +C+ C + + ++I++G+ + CP C + Sbjct: 93 LCSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCPSVATPGQ 152 Query: 392 IESVVSKEMDKRYLQFDIKAFVENNPAIKWCPTPGCDRAVRLTKQGSNTSGSDTLSFPLL 451 ++ +V E+ RY + +++ ++ + +CP P C V + + G + +F Sbjct: 153 VKELVEAELFARYDRLLLQSSLDLMADVVYCPRPCCQLPV-MQEPGCTMGICSSCNFA-- 209 Query: 452 RAPAVDCGKGHLFCWECLGEAHEPCDCQTWKNWLQKITEMKPEELVG------------- 498 FC C H C K +K+ +++ E L Sbjct: 210 ------------FCTLCRLTYHGVSPC---KVTAEKLMDLRNEYLQADEANKRLLDQRYG 254 Query: 499 ---VSEAYEDAANCLWLLTNSKPCANCKSPIQKNEGCNHMQCAKCKYDFCWICL 549 + +A E+ + WL NSK C C +PI+K +GCN M C C FCWIC+ Sbjct: 255 KRVIQKALEEMESKEWLEKNSKSCPCCGTPIEKLDGCNKMTCTGCMQYFCWICM 308 >gi|4757762 ring finger protein 14 isoform 1 [Homo sapiens] Length = 474 Score = 93.6 bits (231), Expect = 9e-19 Identities = 58/234 (24%), Positives = 99/234 (42%), Gaps = 34/234 (14%) Query: 332 LCDICMCSISVFEDPVDMPCGHDFCRGCWESFLNLKIQEGEAHNIFCPAYDCFQLVPVDI 391 LC IC C E + C H +C+ C + + ++I++G+ + CP C + Sbjct: 219 LCSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCPSVATPGQ 278 Query: 392 IESVVSKEMDKRYLQFDIKAFVENNPAIKWCPTPGCDRAVRLTKQGSNTSGSDTLSFPLL 451 ++ +V E+ RY + +++ ++ + +CP P C V + + G + +F Sbjct: 279 VKELVEAELFARYDRLLLQSSLDLMADVVYCPRPCCQLPV-MQEPGCTMGICSSCNFA-- 335 Query: 452 RAPAVDCGKGHLFCWECLGEAHEPCDCQTWKNWLQKITEMKPEELVG------------- 498 FC C H C K +K+ +++ E L Sbjct: 336 ------------FCTLCRLTYHGVSPC---KVTAEKLMDLRNEYLQADEANKRLLDQRYG 380 Query: 499 ---VSEAYEDAANCLWLLTNSKPCANCKSPIQKNEGCNHMQCAKCKYDFCWICL 549 + +A E+ + WL NSK C C +PI+K +GCN M C C FCWIC+ Sbjct: 381 KRVIQKALEEMESKEWLEKNSKSCPCCGTPIEKLDGCNKMTCTGCMQYFCWICM 434 >gi|188219579 ring finger protein 19B isoform b [Homo sapiens] Length = 587 Score = 93.2 bits (230), Expect = 1e-18 Identities = 61/225 (27%), Positives = 99/225 (44%), Gaps = 29/225 (12%) Query: 333 CDICMCSISVFEDPVDMPCGHDFCRGCWESFLNLKIQEGEAHNIFCPAYDCFQ-LVPVDI 391 C +C+ + P + C H CR C +L L+I E I CP +C + L P DI Sbjct: 119 CPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESRVP-ISCP--ECSERLNPHDI 175 Query: 392 IESVVSKEMDKRYLQFDIKAFVENNPAIKWCPTPGCDRAVRLTKQGSNTSGSDTLSFPLL 451 + + +Y +F ++ ++ ++P +WCP P C AV +++ Sbjct: 176 RLLLADPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAV--------------IAYGCA 221 Query: 452 RAPAVDC---GKGHLFCWECLGEAHEPCDCQTWKNWLQKITEMKPEELVGVSEAYEDAAN 508 P + C G FC+ C H C + + ++ + G+S E + Sbjct: 222 SCPKLTCEREGCQTEFCYHCKQIWHPNQTCDMARQQRAQTLRVRTKHTSGLSYGQESGPD 281 Query: 509 CLWLLTNSKPCANCKSPIQK-NEG-CNHMQCAKCKYDFCWICLEE 551 + KPC C + I K N+G CNHM CA C +FCW+C++E Sbjct: 282 DI------KPCPRCSAYIIKMNDGSCNHMTCAVCGCEFCWLCMKE 320 >gi|188219577 ring finger protein 19B isoform a [Homo sapiens] Length = 732 Score = 92.4 bits (228), Expect = 2e-18 Identities = 61/225 (27%), Positives = 98/225 (43%), Gaps = 28/225 (12%) Query: 333 CDICMCSISVFEDPVDMPCGHDFCRGCWESFLNLKIQEGEAHNIFCPAYDCFQ-LVPVDI 391 C +C+ + P + C H CR C +L L+I E I CP +C + L P DI Sbjct: 119 CPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESRVP-ISCP--ECSERLNPHDI 175 Query: 392 IESVVSKEMDKRYLQFDIKAFVENNPAIKWCPTPGCDRAVRLTKQGSNTSGSDTLSFPLL 451 + + +Y +F ++ ++ ++P +WCP P C AV +++ Sbjct: 176 RLLLADPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAV--------------IAYGCA 221 Query: 452 RAPAVDC---GKGHLFCWECLGEAHEPCDCQTWKNWLQKITEMKPEELVGVSEAYEDAAN 508 P + C G FC+ C H C + + ++ + G+S E Sbjct: 222 SCPKLTCEREGCQTEFCYHCKQIWHPNQTCDMARQQRAQTLRVRTKHTSGLSYGQESGP- 280 Query: 509 CLWLLTNSKPCANCKSPIQK-NEG-CNHMQCAKCKYDFCWICLEE 551 + KPC C + I K N+G CNHM CA C +FCW+C++E Sbjct: 281 ----ADDIKPCPRCSAYIIKMNDGSCNHMTCAVCGCEFCWLCMKE 321 >gi|38045938 ring finger protein 144 [Homo sapiens] Length = 292 Score = 80.5 bits (197), Expect = 8e-15 Identities = 63/230 (27%), Positives = 90/230 (39%), Gaps = 32/230 (13%) Query: 329 DTSLCDICMCSISVFEDPVDM-----PCGHDFCRGCWESFLNLKIQEGEAHNIFCPAYDC 383 D +L + C + + E PV+ C FC C + ++ L I+EG I CP C Sbjct: 11 DLALDPLVSCKLCLGEYPVEQMTTIAQCQCIFCTLCLKQYVELLIKEGLETAISCPDAAC 70 Query: 384 FQL--VPVDIIESVVSKEMDKRYLQFDIKAFVENNPAIKWCPTPGCDRAVRLTKQGSNTS 441 + + + IE +V+ E+ +RY + + V +P WCP C +L G T Sbjct: 71 PKQGHLQENEIECMVAAEIMQRYKKLQFEREVLFDPCRTWCPASTCQAVCQLQDVGLQTP 130 Query: 442 GSDTLSFPLLRAPAVDCGKGHL-FCWECLGEAHEPCDCQTWKNWLQKITEMKPEELVGVS 500 V C + FC C H C IT + E Sbjct: 131 ------------QPVQCKACRMEFCSTCKASWHPGQGCPE----TMPITFLPGETSAAFK 174 Query: 501 EAYEDAANCLWLLTNSKPCANCKSPIQKNEGCNHMQCAKCKYDFCWICLE 550 +DA K C CK I+++EGC M C CK+ FCW CLE Sbjct: 175 MEEDDAP--------IKRCPKCKVYIERDEGCAQMMCKNCKHAFCWYCLE 216 >gi|50284696 IBR domain containing 2 [Homo sapiens] Length = 303 Score = 79.0 bits (193), Expect = 2e-14 Identities = 62/233 (26%), Positives = 92/233 (39%), Gaps = 32/233 (13%) Query: 324 SPGDLDTS---LCDICMCSISVFEDPVDMPCGHDFCRGCWESFLNLKIQEGEAHNIFCPA 380 +PGDL + C +C+C S+ + C FC C + ++ L I+EG I CP Sbjct: 18 TPGDLAPAPLITCKLCLCEQSLDKMTTLQECQCIFCTACLKQYMQLAIREGCGSPITCPD 77 Query: 381 YDCFQ--LVPVDIIESVVSKEMDKRYLQFDIKAFVENNPAIKWCPTPGCDRAVRLTKQGS 438 C + I +V + + Y + + V +P WCP C + S Sbjct: 78 MVCLNHGTLQEAEIACLVPVDQFQLYQRLKFEREVHLDPYRTWCPVADCQTVCPV---AS 134 Query: 439 NTSGSDTLSFPLLRAPAVDCGKGHL-FCWECLGEAHEPCDCQTWKNWLQKITEMKPEELV 497 + G L V+C HL FC C H C ++ + + L Sbjct: 135 SDPGQPVL---------VECPSCHLKFCSCCKDAWHAEVSC---RDSQPIVLPTEHRALF 182 Query: 498 GVSEAYEDAANCLWLLTNSKPCANCKSPIQKNEGCNHMQCAKCKYDFCWICLE 550 G DA + K C C+ I++NEGC M C CK+ FCW CL+ Sbjct: 183 GT-----DAEAPI------KQCPVCRVYIERNEGCAQMMCKNCKHTFCWYCLQ 224 >gi|22749145 ring finger protein 217 [Homo sapiens] Length = 275 Score = 65.1 bits (157), Expect = 3e-10 Identities = 44/189 (23%), Positives = 83/189 (43%), Gaps = 23/189 (12%) Query: 366 LKIQEGEAHNIFCPAYDCFQLVPVDIIESVVSKEMDKRYLQFDIKAFVENNPAIKWCPTP 425 +K+Q G+ I CP +CF+ + + ++ E +Y F ++++ P P Sbjct: 1 MKVQLGQVE-IKCPITECFEFLEETTVVYNLTHEDSIKYKYFLELGRIDSSTK----PCP 55 Query: 426 GCDRAVRLTKQGSNTSGSDTLSFPLLRAPAVDCGKGHLFCWECLGEAHEPCDCQTWKNWL 485 C K+G + S + S ++ P ++C++C HE +C+ +K Sbjct: 56 QCKHFTTFKKKGHIPTPSRSESKYKIQCPTCQ----FVWCFKCHSPWHEGVNCKEYKKGD 111 Query: 486 QKITEMKPEELVGVSEAYEDAANCLWLLTNSKPCANCKSPIQKNEGCNHMQCAKCKYDFC 545 + + E G N++ C CK IQ+ EGC+HM C++C +FC Sbjct: 112 KLLRHWASEIEHGQR--------------NAQKCPKCKIHIQRTEGCDHMTCSQCNTNFC 157 Query: 546 WICLEEWKK 554 + C E +++ Sbjct: 158 YRCGERYRQ 166 >gi|169790973 parkin isoform 3 [Homo sapiens] Length = 316 Score = 64.3 bits (155), Expect = 6e-10 Identities = 44/169 (26%), Positives = 71/169 (42%), Gaps = 28/169 (16%) Query: 395 VVSKEMDKRYLQFDIKAFVENNPAIKWCPTPGCDRAV-------RLTKQGSNTSGSDTLS 447 ++ +E RY Q+ + V + CP PGC + ++T +G N G Sbjct: 157 ILGEEQYNRYQQYGAEECVLQMGGVL-CPRPGCGAGLLPEPDQRKVTCEGGNGLGC---- 211 Query: 448 FPLLRAPAVDCGKGHLFCWECLGEAHEPCDCQTWKNWLQKITEMKPEELVGVSEAYEDAA 507 G FC EC EA+ +C T+ + +A +AA Sbjct: 212 -------------GFAFCRECK-EAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAA 257 Query: 508 NCLWLLTNSKPCANCKSPIQKNEGCNHMQC--AKCKYDFCWICLEEWKK 554 + + +KPC C P++KN GC HM+C +C+ ++CW C EW + Sbjct: 258 SKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNR 306 >gi|169790971 parkin isoform 2 [Homo sapiens] Length = 437 Score = 64.3 bits (155), Expect = 6e-10 Identities = 44/169 (26%), Positives = 71/169 (42%), Gaps = 28/169 (16%) Query: 395 VVSKEMDKRYLQFDIKAFVENNPAIKWCPTPGCDRAV-------RLTKQGSNTSGSDTLS 447 ++ +E RY Q+ + V + CP PGC + ++T +G N G Sbjct: 278 ILGEEQYNRYQQYGAEECVLQMGGVL-CPRPGCGAGLLPEPDQRKVTCEGGNGLGC---- 332 Query: 448 FPLLRAPAVDCGKGHLFCWECLGEAHEPCDCQTWKNWLQKITEMKPEELVGVSEAYEDAA 507 G FC EC EA+ +C T+ + +A +AA Sbjct: 333 -------------GFAFCRECK-EAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAA 378 Query: 508 NCLWLLTNSKPCANCKSPIQKNEGCNHMQC--AKCKYDFCWICLEEWKK 554 + + +KPC C P++KN GC HM+C +C+ ++CW C EW + Sbjct: 379 SKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNR 427 >gi|169790969 parkin isoform 1 [Homo sapiens] Length = 465 Score = 64.3 bits (155), Expect = 6e-10 Identities = 44/169 (26%), Positives = 71/169 (42%), Gaps = 28/169 (16%) Query: 395 VVSKEMDKRYLQFDIKAFVENNPAIKWCPTPGCDRAV-------RLTKQGSNTSGSDTLS 447 ++ +E RY Q+ + V + CP PGC + ++T +G N G Sbjct: 306 ILGEEQYNRYQQYGAEECVLQMGGVL-CPRPGCGAGLLPEPDQRKVTCEGGNGLGC---- 360 Query: 448 FPLLRAPAVDCGKGHLFCWECLGEAHEPCDCQTWKNWLQKITEMKPEELVGVSEAYEDAA 507 G FC EC EA+ +C T+ + +A +AA Sbjct: 361 -------------GFAFCRECK-EAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAA 406 Query: 508 NCLWLLTNSKPCANCKSPIQKNEGCNHMQC--AKCKYDFCWICLEEWKK 554 + + +KPC C P++KN GC HM+C +C+ ++CW C EW + Sbjct: 407 SKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNR 455 >gi|116063534 ankyrin repeat domain 27 (VPS9 domain) [Homo sapiens] Length = 1050 Score = 63.2 bits (152), Expect = 1e-09 Identities = 53/186 (28%), Positives = 76/186 (40%), Gaps = 14/186 (7%) Query: 47 NTPLHYAARHGMNKILGTFLGRDGNPNKRNVHNETSMHLLCMGPQIMISEGALHPRLARP 106 ++PLH AA HG ++ L N RN +HL C + + L A+P Sbjct: 745 SSPLHVAALHGRADLIPLLLKHGANAGARNADQAVPLHLACQQGHFQVVKCLLDSN-AKP 803 Query: 107 TEDDFRRADCLQMILKWKGAK-------LDQGEYERAAIDAVDNKKNTPLHYAAASGMKA 159 + D + +I G L G A+I+A +NK NT LH A Sbjct: 804 NKKDL--SGNTPLIYACSGGHHELVALLLQHG----ASINASNNKGNTALHEAVIEKHVF 857 Query: 160 CVELLVKHGGDLFAENENKDTPCDCAEKQHHKDLALNLESQMVFSRDPEAEEIEAEYAAL 219 VELL+ HG + N+ + T DCAE+ L + V S D AE EY + Sbjct: 858 VVELLLLHGASVQVLNKRQRTAVDCAEQNSKIMELLQVVPSCVASLDDVAETDRKEYVTV 917 Query: 220 DKREPY 225 R+ + Sbjct: 918 KIRKKW 923 Score = 61.6 bits (148), Expect = 4e-09 Identities = 40/164 (24%), Positives = 73/164 (44%), Gaps = 21/164 (12%) Query: 35 DPN--TSYGEPYQHNTPLHYAARHGMNKILGTFLGRDGNPNKRNVHNETSMHLLCMGPQI 92 DP+ T + + +TPLH AA G ++ + + N + H T +HL C Sbjct: 450 DPSVVTPFSRDDRGHTPLHVAAVCGQASLIDLLVSKGAMVNATDYHGATPLHLACQKGYQ 509 Query: 93 MISEGALHPRLARPTEDD-----------FRRADCLQMILKWKGAKLDQGEYERAAIDAV 141 ++ LH + + +D+ + DC++ ++ + + E +D Sbjct: 510 SVTLLLLHYKASAEVQDNNGNTPLHLACTYGHEDCVKALVYY--------DVESCRLDIG 561 Query: 142 DNKKNTPLHYAAASGMKACVELLVKHGGDLFAENENKDTPCDCA 185 + K +TPLH AA G + +E L+++G +N K+TP CA Sbjct: 562 NEKGDTPLHIAARWGYQGVIETLLQNGASTEIQNRLKETPLKCA 605 Score = 35.4 bits (80), Expect = 0.30 Identities = 17/53 (32%), Positives = 27/53 (50%) Query: 138 IDAVDNKKNTPLHYAAASGMKACVELLVKHGGDLFAENENKDTPCDCAEKQHH 190 ++ ++PLH AA G + LL+KHG + A N ++ P A +Q H Sbjct: 737 VNVTSQDGSSPLHVAALHGRADLIPLLLKHGANAGARNADQAVPLHLACQQGH 789 Score = 34.3 bits (77), Expect = 0.66 Identities = 18/56 (32%), Positives = 32/56 (57%) Query: 142 DNKKNTPLHYAAASGMKACVELLVKHGGDLFAENENKDTPCDCAEKQHHKDLALNL 197 D++ +TPLH AA G + ++LLV G + A + + TP A ++ ++ + L L Sbjct: 460 DDRGHTPLHVAAVCGQASLIDLLVSKGAMVNATDYHGATPLHLACQKGYQSVTLLL 515 Score = 32.0 bits (71), Expect = 3.3 Identities = 17/57 (29%), Positives = 27/57 (47%) Query: 136 AAIDAVDNKKNTPLHYAAASGMKACVELLVKHGGDLFAENENKDTPCDCAEKQHHKD 192 A ++A D TPLH A G ++ LL+ + ++ N +TP A H+D Sbjct: 487 AMVNATDYHGATPLHLACQKGYQSVTLLLLHYKASAEVQDNNGNTPLHLACTYGHED 543 >gi|5454168 RanBP-type and C3HC4-type zinc finger containing 1 isoform 1 [Homo sapiens] Length = 468 Score = 54.3 bits (129), Expect = 6e-07 Identities = 51/220 (23%), Positives = 87/220 (39%), Gaps = 31/220 (14%) Query: 333 CDICMCSISVFEDPVDMPCGHDFCRGCWESFLNLKIQEGEAHNIFCP----AYDCFQLVP 388 C +C ++ E V C H FCR C L I+ + + CP Y C + Sbjct: 240 CPVCYSVLAPGEAVVLRECLHTFCREC----LQGTIRNSQEAEVSCPFIDNTYSCSGKLL 295 Query: 389 VDIIESVVSKEMDKRYLQFDIKAFVENNPAIKW-CPTPGCDRAVRLTKQGSNTSGSDTLS 447 I+++++ E +R+L I + EN A + C TP C +G D Sbjct: 296 EREIKALLTPEDYQRFLDLGI-SIAENRSAFSYHCKTPDC--------KGWCFFEDDVNE 346 Query: 448 FPLLRAPAVDCGKGHLFCWECLGEAHEPCDCQTWKNWLQKITEMKPEELVGVSEAYEDAA 507 F V+C L C HE +C+ + Q+ ++ + V + E Sbjct: 347 FTCPVCFHVNC----LLC----KAIHEQMNCKEY----QEDLALRAQNDVAARQTTE-ML 393 Query: 508 NCLWLLTNSKPCANCKSPIQKNEGCNHMQCAKCKYDFCWI 547 + + C C+ +QK +GC+ ++C C + CW+ Sbjct: 394 KVMLQQGEAMRCPQCQIVVQKKDGCDWIRCTVCHTEICWV 433 >gi|144953898 RanBP-type and C3HC4-type zinc finger containing 1 isoform 2 [Homo sapiens] Length = 510 Score = 54.3 bits (129), Expect = 6e-07 Identities = 51/220 (23%), Positives = 87/220 (39%), Gaps = 31/220 (14%) Query: 333 CDICMCSISVFEDPVDMPCGHDFCRGCWESFLNLKIQEGEAHNIFCP----AYDCFQLVP 388 C +C ++ E V C H FCR C L I+ + + CP Y C + Sbjct: 282 CPVCYSVLAPGEAVVLRECLHTFCREC----LQGTIRNSQEAEVSCPFIDNTYSCSGKLL 337 Query: 389 VDIIESVVSKEMDKRYLQFDIKAFVENNPAIKW-CPTPGCDRAVRLTKQGSNTSGSDTLS 447 I+++++ E +R+L I + EN A + C TP C +G D Sbjct: 338 EREIKALLTPEDYQRFLDLGI-SIAENRSAFSYHCKTPDC--------KGWCFFEDDVNE 388 Query: 448 FPLLRAPAVDCGKGHLFCWECLGEAHEPCDCQTWKNWLQKITEMKPEELVGVSEAYEDAA 507 F V+C L C HE +C+ + Q+ ++ + V + E Sbjct: 389 FTCPVCFHVNC----LLC----KAIHEQMNCKEY----QEDLALRAQNDVAARQTTE-ML 435 Query: 508 NCLWLLTNSKPCANCKSPIQKNEGCNHMQCAKCKYDFCWI 547 + + C C+ +QK +GC+ ++C C + CW+ Sbjct: 436 KVMLQQGEAMRCPQCQIVVQKKDGCDWIRCTVCHTEICWV 475 >gi|24586688 ankyrin repeat and SOCS box-containing protein 16 [Homo sapiens] Length = 453 Score = 52.8 bits (125), Expect = 2e-06 Identities = 45/149 (30%), Positives = 64/149 (42%), Gaps = 27/149 (18%) Query: 37 NTSYGEPYQHNTPLHYAARHGMNKILGTFLGRDGNPNKRNVHNETSMHLLCMGPQIMISE 96 N + GE + TPLH AA G+ + + +L + R ET+++ C G +E Sbjct: 203 NLAAGESQE--TPLHVAAARGLEQHVALYLEHGADVGLRTSQGETALNTACAG-----AE 255 Query: 97 GALHPRLARPTEDDFRRADCLQMILKWKGAKLDQGEYERAAIDAVDNKKNTPLHYAAASG 156 G P R + RR L+ G RAA K++TPLH A A+G Sbjct: 256 G---PGSCRRHQAAARRL-------------LEAGADARAA----GRKRHTPLHNACANG 295 Query: 157 MKACVELLVKHGGDLFAENENKDTPCDCA 185 ELL+++G N TP DCA Sbjct: 296 CGGLAELLLRYGARAEVPNGAGHTPMDCA 324 Score = 31.6 bits (70), Expect = 4.3 Identities = 32/126 (25%), Positives = 57/126 (45%), Gaps = 22/126 (17%) Query: 78 HNETSMHLLCMGPQIMISEG---ALHPRLARPTEDDFRRADCLQMILKWKGAKLDQGEYE 134 + + + HL+ G ++ G ALH AR + DC++++L + GAK + Sbjct: 123 YTDCARHLIRQGAELDARVGGRAALHEACARA------QFDCVRLLLTF-GAKAN----- 170 Query: 135 RAAIDAVDNKKNTPLHYAAASGMKACVELLVKHGGDL-FAENENKDTPCD-CAEKQHHKD 192 + + TPLH C +LL++ G + A E+++TP A + + Sbjct: 171 -----VLTEEGTTPLHLCTIPESLQCAKLLLEAGATVNLAAGESQETPLHVAAARGLEQH 225 Query: 193 LALNLE 198 +AL LE Sbjct: 226 VALYLE 231 >gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens] Length = 2039 Score = 52.4 bits (124), Expect = 2e-06 Identities = 40/126 (31%), Positives = 67/126 (53%), Gaps = 8/126 (6%) Query: 146 NTPLHYAAASGMKACVELLVKHGGDLFAENENKDTPCDCAEKQHHKDLALNLESQMVFSR 205 +TPLH +A+SG + V+LL++HGG+ F N++ + P D AE + +L L L+ ++ S Sbjct: 229 DTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPVDVAETE---ELELLLKREVPLSD 285 Query: 206 DPEAEEIEAEYAALDKREPYEGLRPQDLRRLKDMLIVETADML--QAPLFTAEALLRAHD 263 D E+ E +++ E + D KD LI E+ +L + PL +A D Sbjct: 286 DDESYTDSEEAQSVNPSSVDENI---DSETEKDSLICESKQILPSKTPLPSALDEYEFKD 342 Query: 264 WDREKL 269 D E++ Sbjct: 343 DDDEEI 348 >gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens] Length = 2062 Score = 52.4 bits (124), Expect = 2e-06 Identities = 40/126 (31%), Positives = 67/126 (53%), Gaps = 8/126 (6%) Query: 146 NTPLHYAAASGMKACVELLVKHGGDLFAENENKDTPCDCAEKQHHKDLALNLESQMVFSR 205 +TPLH +A+SG + V+LL++HGG+ F N++ + P D AE + +L L L+ ++ S Sbjct: 252 DTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPVDVAETE---ELELLLKREVPLSD 308 Query: 206 DPEAEEIEAEYAALDKREPYEGLRPQDLRRLKDMLIVETADML--QAPLFTAEALLRAHD 263 D E+ E +++ E + D KD LI E+ +L + PL +A D Sbjct: 309 DDESYTDSEEAQSVNPSSVDENI---DSETEKDSLICESKQILPSKTPLPSALDEYEFKD 365 Query: 264 WDREKL 269 D E++ Sbjct: 366 DDDEEI 371 >gi|4506217 proteasome 26S non-ATPase subunit 10 isoform 1 [Homo sapiens] Length = 226 Score = 51.6 bits (122), Expect = 4e-06 Identities = 37/143 (25%), Positives = 62/143 (43%), Gaps = 8/143 (5%) Query: 48 TPLHYAARHGMNKILGTFLGRDGNPNKRNVHNETSMHLLCMGPQ----IMISEGALHPRL 103 +PLH AA G ++I+ LG+ N N + T +H + +M+ EG +P Sbjct: 75 SPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANP-- 132 Query: 104 ARPTEDDFRRADCLQMILKWKGAKLDQGEYERAAIDAVDNKKNTPLHYAAASGMKACVEL 163 +D + + K + Y +A+ + D + NTPLH A +L Sbjct: 133 --DAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKL 190 Query: 164 LVKHGGDLFAENENKDTPCDCAE 186 LV G ++ EN+ + TP A+ Sbjct: 191 LVSQGASIYIENKEEKTPLQVAK 213 Score = 33.5 bits (75), Expect = 1.1 Identities = 17/51 (33%), Positives = 29/51 (56%) Query: 147 TPLHYAAASGMKACVELLVKHGGDLFAENENKDTPCDCAEKQHHKDLALNL 197 +PLH AA++G V+ L+ G + A N+N TP A ++ ++A+ L Sbjct: 75 SPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVML 125 >gi|215598574 ankyrin 1 isoform 9 [Homo sapiens] Length = 1897 Score = 51.2 bits (121), Expect = 5e-06 Identities = 39/151 (25%), Positives = 66/151 (43%), Gaps = 6/151 (3%) Query: 46 HNTPLHYAARHGMNKILGTFLGRDGNPNKRNVHNETSMHLLCMGPQIMISEGALH--PRL 103 H TPLH AA G +++ L + PN R ++ T +H+ C + + E L + Sbjct: 371 HLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASI 430 Query: 104 ARPTEDDFRRADCLQMILKWKGAKLDQGEYERAAIDAVDN-KKNTPLHYAAASGMKACVE 162 TE L + + + +R A V N K TPLH AA +G + Sbjct: 431 DAVTESGLTP---LHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAK 487 Query: 163 LLVKHGGDLFAENENKDTPCDCAEKQHHKDL 193 L+++ + A+ ++ TP CA + H ++ Sbjct: 488 YLLQNKAKVNAKAKDDQTPLHCAARIGHTNM 518 Score = 43.9 bits (102), Expect = 8e-04 Identities = 47/188 (25%), Positives = 81/188 (43%), Gaps = 24/188 (12%) Query: 39 SYGEPYQHNTP-LHYAARHGMNKILGTFLGRDGNPNKRNVHNETSMHLLCMGP-----QI 92 +YG + P LH AAR+ + L D NP+ + T +H+ Q+ Sbjct: 198 NYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQL 257 Query: 93 MISEGA---LHPRLA-RPTEDDFRRADCLQMILKWKGAKLDQGEYERAAIDAVDNKKNTP 148 +++ GA P+ P RR + + + L LD+G A I+ + TP Sbjct: 258 LLNRGASVNFTPQNGITPLHIASRRGNVIMVRLL-----LDRG----AQIETKTKDELTP 308 Query: 149 LHYAAASGMKACVELLVKHGGDLFAENENKDTPCDCAEKQHHKDLALNLESQMVFSRDPE 208 LH AA +G E+L+ HG + A+ +N +P A + H D +++ D E Sbjct: 309 LHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCV-----RLLLQYDAE 363 Query: 209 AEEIEAEY 216 ++I ++ Sbjct: 364 IDDITLDH 371 Score = 43.9 bits (102), Expect = 8e-04 Identities = 41/153 (26%), Positives = 62/153 (40%), Gaps = 6/153 (3%) Query: 48 TPLHYAARHGMNKILGTFLGRDGNPNKRNVHNETSMHLLCMGPQIMISEGALHPRLARP- 106 TPLH AAR G ++ L + NPN T +H+ + L ++ Sbjct: 505 TPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQAC 564 Query: 107 -TEDDFRRADCLQMILKWKGAKLDQGEYERAAIDAVDNKKN-TPLHYAAASGMKACVELL 164 T+ F L + K+ ++ + ER A K TPLH A V+LL Sbjct: 565 MTKKGFTP---LHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLL 621 Query: 165 VKHGGDLFAENENKDTPCDCAEKQHHKDLALNL 197 + GG + N TP A KQ+ ++A +L Sbjct: 622 LPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSL 654 Score = 43.1 bits (100), Expect = 0.001 Identities = 41/182 (22%), Positives = 71/182 (39%), Gaps = 35/182 (19%) Query: 14 NGDENLACQIYENNPQLKESLDP--NTSYGEPYQHNTPLHYAARHGMNKILGTFLGRDGN 71 NG L +N ++ SL ++ E Q TPLH AA+ G +++ L + N Sbjct: 634 NGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQAN 693 Query: 72 PNKRNVHNETSMHLLCMGPQIMISEGALHPRLARPTEDDFRRADCLQMILKWKGAKLDQG 131 N N T +HL+ + +++ +++K Sbjct: 694 GNLGNKSGLTPLHLVAQEGHVPVAD----------------------VLIK--------- 722 Query: 132 EYERAAIDAVDNKKNTPLHYAAASGMKACVELLVKHGGDLFAENENKDTPCDCAEKQHHK 191 +DA TPLH A+ G V+ L++H D+ A+ + +P A +Q H Sbjct: 723 --HGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHT 780 Query: 192 DL 193 D+ Sbjct: 781 DI 782 Score = 42.4 bits (98), Expect = 0.002 Identities = 41/153 (26%), Positives = 65/153 (42%), Gaps = 12/153 (7%) Query: 48 TPLHYAARHGMNKILGTFLGRDGNPNKRNVHNETSMHLLCMGPQIMISEGALHPRLARPT 107 TPLH AA++G ++ L RD +PN + T +H+ + I + L PR P Sbjct: 571 TPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVK-LLLPRGGSPH 629 Query: 108 EDDFRRADCLQMILKWKGAKLDQGEYERAAI------DAVDNKKNTPLHYAAASGMKACV 161 + L + AK +Q E R+ + +A + TPLH AA G V Sbjct: 630 SPAWNGYTPLHI-----AAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMV 684 Query: 162 ELLVKHGGDLFAENENKDTPCDCAEKQHHKDLA 194 LL+ + N++ TP ++ H +A Sbjct: 685 ALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVA 717 Score = 36.6 bits (83), Expect = 0.13 Identities = 38/159 (23%), Positives = 60/159 (37%), Gaps = 22/159 (13%) Query: 43 PYQHNTPLHYAARHGMNKILGTFLGRDGNPNKRNVHNETSMHLLCMGPQIMISEGALH-- 100 P TPLH A+R G ++ L R + T +H + ISE L Sbjct: 269 PQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHG 328 Query: 101 PRLARPTEDDFR---------RADCLQMILKWKGAKLDQGEYERAAIDAVDNKKNTPLHY 151 + T++ DC++++L++ A ID + TPLH Sbjct: 329 APIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYD-----------AEIDDITLDHLTPLHV 377 Query: 152 AAASGMKACVELLVKHGGDLFAENENKDTPCDCAEKQHH 190 AA G ++L+ G + N TP A K++H Sbjct: 378 AAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNH 416 Score = 36.2 bits (82), Expect = 0.17 Identities = 17/61 (27%), Positives = 33/61 (54%) Query: 133 YERAAIDAVDNKKNTPLHYAAASGMKACVELLVKHGGDLFAENENKDTPCDCAEKQHHKD 192 ++ ++ K NT LH AA +G V LV +G ++ A+++ TP A +++H + Sbjct: 99 HKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLE 158 Query: 193 L 193 + Sbjct: 159 V 159 Score = 31.2 bits (69), Expect = 5.6 Identities = 35/154 (22%), Positives = 61/154 (39%), Gaps = 14/154 (9%) Query: 48 TPLHYAARHGMNKILGTFLGRDGNPNKRNVHNETSMHLLC-----MGPQIMISEGALHPR 102 TPLH AA + + L R + N + T +H+ + ++++ GA + Sbjct: 241 TPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGA---Q 297 Query: 103 LARPTEDDFRRADCLQMI--LKWKGAKLDQGEYERAAIDAVDNKKNTPLHYAAASGMKAC 160 + T+D+ C ++ LD G A I A +P+H AA C Sbjct: 298 IETKTKDELTPLHCAARNGHVRISEILLDHG----APIQAKTKNGLSPIHMAAQGDHLDC 353 Query: 161 VELLVKHGGDLFAENENKDTPCDCAEKQHHKDLA 194 V LL+++ ++ + TP A H +A Sbjct: 354 VRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVA 387 Score = 30.8 bits (68), Expect = 7.3 Identities = 18/62 (29%), Positives = 32/62 (51%) Query: 136 AAIDAVDNKKNTPLHYAAASGMKACVELLVKHGGDLFAENENKDTPCDCAEKQHHKDLAL 195 A ++A K TPL+ AA V+ L+++G + E+ TP A +Q H+++ Sbjct: 135 ANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVA 194 Query: 196 NL 197 +L Sbjct: 195 HL 196 >gi|70780359 ankyrin 1 isoform 1 [Homo sapiens] Length = 1881 Score = 51.2 bits (121), Expect = 5e-06 Identities = 39/151 (25%), Positives = 66/151 (43%), Gaps = 6/151 (3%) Query: 46 HNTPLHYAARHGMNKILGTFLGRDGNPNKRNVHNETSMHLLCMGPQIMISEGALH--PRL 103 H TPLH AA G +++ L + PN R ++ T +H+ C + + E L + Sbjct: 338 HLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASI 397 Query: 104 ARPTEDDFRRADCLQMILKWKGAKLDQGEYERAAIDAVDN-KKNTPLHYAAASGMKACVE 162 TE L + + + +R A V N K TPLH AA +G + Sbjct: 398 DAVTESGLTP---LHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAK 454 Query: 163 LLVKHGGDLFAENENKDTPCDCAEKQHHKDL 193 L+++ + A+ ++ TP CA + H ++ Sbjct: 455 YLLQNKAKVNAKAKDDQTPLHCAARIGHTNM 485 Score = 43.9 bits (102), Expect = 8e-04 Identities = 47/188 (25%), Positives = 81/188 (43%), Gaps = 24/188 (12%) Query: 39 SYGEPYQHNTP-LHYAARHGMNKILGTFLGRDGNPNKRNVHNETSMHLLCMGP-----QI 92 +YG + P LH AAR+ + L D NP+ + T +H+ Q+ Sbjct: 165 NYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQL 224 Query: 93 MISEGA---LHPRLA-RPTEDDFRRADCLQMILKWKGAKLDQGEYERAAIDAVDNKKNTP 148 +++ GA P+ P RR + + + L LD+G A I+ + TP Sbjct: 225 LLNRGASVNFTPQNGITPLHIASRRGNVIMVRLL-----LDRG----AQIETKTKDELTP 275 Query: 149 LHYAAASGMKACVELLVKHGGDLFAENENKDTPCDCAEKQHHKDLALNLESQMVFSRDPE 208 LH AA +G E+L+ HG + A+ +N +P A + H D +++ D E Sbjct: 276 LHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCV-----RLLLQYDAE 330 Query: 209 AEEIEAEY 216 ++I ++ Sbjct: 331 IDDITLDH 338 Score = 43.9 bits (102), Expect = 8e-04 Identities = 41/153 (26%), Positives = 62/153 (40%), Gaps = 6/153 (3%) Query: 48 TPLHYAARHGMNKILGTFLGRDGNPNKRNVHNETSMHLLCMGPQIMISEGALHPRLARP- 106 TPLH AAR G ++ L + NPN T +H+ + L ++ Sbjct: 472 TPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQAC 531 Query: 107 -TEDDFRRADCLQMILKWKGAKLDQGEYERAAIDAVDNKKN-TPLHYAAASGMKACVELL 164 T+ F L + K+ ++ + ER A K TPLH A V+LL Sbjct: 532 MTKKGFTP---LHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLL 588 Query: 165 VKHGGDLFAENENKDTPCDCAEKQHHKDLALNL 197 + GG + N TP A KQ+ ++A +L Sbjct: 589 LPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSL 621 Score = 43.1 bits (100), Expect = 0.001 Identities = 41/182 (22%), Positives = 71/182 (39%), Gaps = 35/182 (19%) Query: 14 NGDENLACQIYENNPQLKESLDP--NTSYGEPYQHNTPLHYAARHGMNKILGTFLGRDGN 71 NG L +N ++ SL ++ E Q TPLH AA+ G +++ L + N Sbjct: 601 NGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQAN 660 Query: 72 PNKRNVHNETSMHLLCMGPQIMISEGALHPRLARPTEDDFRRADCLQMILKWKGAKLDQG 131 N N T +HL+ + +++ +++K Sbjct: 661 GNLGNKSGLTPLHLVAQEGHVPVAD----------------------VLIK--------- 689 Query: 132 EYERAAIDAVDNKKNTPLHYAAASGMKACVELLVKHGGDLFAENENKDTPCDCAEKQHHK 191 +DA TPLH A+ G V+ L++H D+ A+ + +P A +Q H Sbjct: 690 --HGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHT 747 Query: 192 DL 193 D+ Sbjct: 748 DI 749 Score = 42.4 bits (98), Expect = 0.002 Identities = 41/153 (26%), Positives = 65/153 (42%), Gaps = 12/153 (7%) Query: 48 TPLHYAARHGMNKILGTFLGRDGNPNKRNVHNETSMHLLCMGPQIMISEGALHPRLARPT 107 TPLH AA++G ++ L RD +PN + T +H+ + I + L PR P Sbjct: 538 TPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVK-LLLPRGGSPH 596 Query: 108 EDDFRRADCLQMILKWKGAKLDQGEYERAAI------DAVDNKKNTPLHYAAASGMKACV 161 + L + AK +Q E R+ + +A + TPLH AA G V Sbjct: 597 SPAWNGYTPLHI-----AAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMV 651 Query: 162 ELLVKHGGDLFAENENKDTPCDCAEKQHHKDLA 194 LL+ + N++ TP ++ H +A Sbjct: 652 ALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVA 684 Score = 36.6 bits (83), Expect = 0.13 Identities = 38/159 (23%), Positives = 60/159 (37%), Gaps = 22/159 (13%) Query: 43 PYQHNTPLHYAARHGMNKILGTFLGRDGNPNKRNVHNETSMHLLCMGPQIMISEGALH-- 100 P TPLH A+R G ++ L R + T +H + ISE L Sbjct: 236 PQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHG 295 Query: 101 PRLARPTEDDFR---------RADCLQMILKWKGAKLDQGEYERAAIDAVDNKKNTPLHY 151 + T++ DC++++L++ A ID + TPLH Sbjct: 296 APIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYD-----------AEIDDITLDHLTPLHV 344 Query: 152 AAASGMKACVELLVKHGGDLFAENENKDTPCDCAEKQHH 190 AA G ++L+ G + N TP A K++H Sbjct: 345 AAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNH 383 Score = 36.2 bits (82), Expect = 0.17 Identities = 17/61 (27%), Positives = 33/61 (54%) Query: 133 YERAAIDAVDNKKNTPLHYAAASGMKACVELLVKHGGDLFAENENKDTPCDCAEKQHHKD 192 ++ ++ K NT LH AA +G V LV +G ++ A+++ TP A +++H + Sbjct: 66 HKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLE 125 Query: 193 L 193 + Sbjct: 126 V 126 Score = 31.2 bits (69), Expect = 5.6 Identities = 35/154 (22%), Positives = 61/154 (39%), Gaps = 14/154 (9%) Query: 48 TPLHYAARHGMNKILGTFLGRDGNPNKRNVHNETSMHLLC-----MGPQIMISEGALHPR 102 TPLH AA + + L R + N + T +H+ + ++++ GA + Sbjct: 208 TPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGA---Q 264 Query: 103 LARPTEDDFRRADCLQMI--LKWKGAKLDQGEYERAAIDAVDNKKNTPLHYAAASGMKAC 160 + T+D+ C ++ LD G A I A +P+H AA C Sbjct: 265 IETKTKDELTPLHCAARNGHVRISEILLDHG----APIQAKTKNGLSPIHMAAQGDHLDC 320 Query: 161 VELLVKHGGDLFAENENKDTPCDCAEKQHHKDLA 194 V LL+++ ++ + TP A H +A Sbjct: 321 VRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVA 354 Score = 30.8 bits (68), Expect = 7.3 Identities = 18/62 (29%), Positives = 32/62 (51%) Query: 136 AAIDAVDNKKNTPLHYAAASGMKACVELLVKHGGDLFAENENKDTPCDCAEKQHHKDLAL 195 A ++A K TPL+ AA V+ L+++G + E+ TP A +Q H+++ Sbjct: 102 ANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVA 161 Query: 196 NL 197 +L Sbjct: 162 HL 163 >gi|70780357 ankyrin 1 isoform 3 [Homo sapiens] Length = 1880 Score = 51.2 bits (121), Expect = 5e-06 Identities = 39/151 (25%), Positives = 66/151 (43%), Gaps = 6/151 (3%) Query: 46 HNTPLHYAARHGMNKILGTFLGRDGNPNKRNVHNETSMHLLCMGPQIMISEGALH--PRL 103 H TPLH AA G +++ L + PN R ++ T +H+ C + + E L + Sbjct: 338 HLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASI 397 Query: 104 ARPTEDDFRRADCLQMILKWKGAKLDQGEYERAAIDAVDN-KKNTPLHYAAASGMKACVE 162 TE L + + + +R A V N K TPLH AA +G + Sbjct: 398 DAVTESGLTP---LHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAK 454 Query: 163 LLVKHGGDLFAENENKDTPCDCAEKQHHKDL 193 L+++ + A+ ++ TP CA + H ++ Sbjct: 455 YLLQNKAKVNAKAKDDQTPLHCAARIGHTNM 485 Score = 43.9 bits (102), Expect = 8e-04 Identities = 47/188 (25%), Positives = 81/188 (43%), Gaps = 24/188 (12%) Query: 39 SYGEPYQHNTP-LHYAARHGMNKILGTFLGRDGNPNKRNVHNETSMHLLCMGP-----QI 92 +YG + P LH AAR+ + L D NP+ + T +H+ Q+ Sbjct: 165 NYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQL 224 Query: 93 MISEGA---LHPRLA-RPTEDDFRRADCLQMILKWKGAKLDQGEYERAAIDAVDNKKNTP 148 +++ GA P+ P RR + + + L LD+G A I+ + TP Sbjct: 225 LLNRGASVNFTPQNGITPLHIASRRGNVIMVRLL-----LDRG----AQIETKTKDELTP 275 Query: 149 LHYAAASGMKACVELLVKHGGDLFAENENKDTPCDCAEKQHHKDLALNLESQMVFSRDPE 208 LH AA +G E+L+ HG + A+ +N +P A + H D +++ D E Sbjct: 276 LHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCV-----RLLLQYDAE 330 Query: 209 AEEIEAEY 216 ++I ++ Sbjct: 331 IDDITLDH 338 Score = 43.9 bits (102), Expect = 8e-04 Identities = 41/153 (26%), Positives = 62/153 (40%), Gaps = 6/153 (3%) Query: 48 TPLHYAARHGMNKILGTFLGRDGNPNKRNVHNETSMHLLCMGPQIMISEGALHPRLARP- 106 TPLH AAR G ++ L + NPN T +H+ + L ++ Sbjct: 472 TPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQAC 531 Query: 107 -TEDDFRRADCLQMILKWKGAKLDQGEYERAAIDAVDNKKN-TPLHYAAASGMKACVELL 164 T+ F L + K+ ++ + ER A K TPLH A V+LL Sbjct: 532 MTKKGFTP---LHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLL 588 Query: 165 VKHGGDLFAENENKDTPCDCAEKQHHKDLALNL 197 + GG + N TP A KQ+ ++A +L Sbjct: 589 LPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSL 621 Score = 43.1 bits (100), Expect = 0.001 Identities = 41/182 (22%), Positives = 71/182 (39%), Gaps = 35/182 (19%) Query: 14 NGDENLACQIYENNPQLKESLDP--NTSYGEPYQHNTPLHYAARHGMNKILGTFLGRDGN 71 NG L +N ++ SL ++ E Q TPLH AA+ G +++ L + N Sbjct: 601 NGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQAN 660 Query: 72 PNKRNVHNETSMHLLCMGPQIMISEGALHPRLARPTEDDFRRADCLQMILKWKGAKLDQG 131 N N T +HL+ + +++ +++K Sbjct: 661 GNLGNKSGLTPLHLVAQEGHVPVAD----------------------VLIK--------- 689 Query: 132 EYERAAIDAVDNKKNTPLHYAAASGMKACVELLVKHGGDLFAENENKDTPCDCAEKQHHK 191 +DA TPLH A+ G V+ L++H D+ A+ + +P A +Q H Sbjct: 690 --HGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHT 747 Query: 192 DL 193 D+ Sbjct: 748 DI 749 Score = 42.4 bits (98), Expect = 0.002 Identities = 41/153 (26%), Positives = 65/153 (42%), Gaps = 12/153 (7%) Query: 48 TPLHYAARHGMNKILGTFLGRDGNPNKRNVHNETSMHLLCMGPQIMISEGALHPRLARPT 107 TPLH AA++G ++ L RD +PN + T +H+ + I + L PR P Sbjct: 538 TPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVK-LLLPRGGSPH 596 Query: 108 EDDFRRADCLQMILKWKGAKLDQGEYERAAI------DAVDNKKNTPLHYAAASGMKACV 161 + L + AK +Q E R+ + +A + TPLH AA G V Sbjct: 597 SPAWNGYTPLHI-----AAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMV 651 Query: 162 ELLVKHGGDLFAENENKDTPCDCAEKQHHKDLA 194 LL+ + N++ TP ++ H +A Sbjct: 652 ALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVA 684 Score = 36.6 bits (83), Expect = 0.13 Identities = 38/159 (23%), Positives = 60/159 (37%), Gaps = 22/159 (13%) Query: 43 PYQHNTPLHYAARHGMNKILGTFLGRDGNPNKRNVHNETSMHLLCMGPQIMISEGALH-- 100 P TPLH A+R G ++ L R + T +H + ISE L Sbjct: 236 PQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHG 295 Query: 101 PRLARPTEDDFR---------RADCLQMILKWKGAKLDQGEYERAAIDAVDNKKNTPLHY 151 + T++ DC++++L++ A ID + TPLH Sbjct: 296 APIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYD-----------AEIDDITLDHLTPLHV 344 Query: 152 AAASGMKACVELLVKHGGDLFAENENKDTPCDCAEKQHH 190 AA G ++L+ G + N TP A K++H Sbjct: 345 AAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNH 383 Score = 36.2 bits (82), Expect = 0.17 Identities = 17/61 (27%), Positives = 33/61 (54%) Query: 133 YERAAIDAVDNKKNTPLHYAAASGMKACVELLVKHGGDLFAENENKDTPCDCAEKQHHKD 192 ++ ++ K NT LH AA +G V LV +G ++ A+++ TP A +++H + Sbjct: 66 HKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLE 125 Query: 193 L 193 + Sbjct: 126 V 126 Score = 31.2 bits (69), Expect = 5.6 Identities = 35/154 (22%), Positives = 61/154 (39%), Gaps = 14/154 (9%) Query: 48 TPLHYAARHGMNKILGTFLGRDGNPNKRNVHNETSMHLLC-----MGPQIMISEGALHPR 102 TPLH AA + + L R + N + T +H+ + ++++ GA + Sbjct: 208 TPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGA---Q 264 Query: 103 LARPTEDDFRRADCLQMI--LKWKGAKLDQGEYERAAIDAVDNKKNTPLHYAAASGMKAC 160 + T+D+ C ++ LD G A I A +P+H AA C Sbjct: 265 IETKTKDELTPLHCAARNGHVRISEILLDHG----APIQAKTKNGLSPIHMAAQGDHLDC 320 Query: 161 VELLVKHGGDLFAENENKDTPCDCAEKQHHKDLA 194 V LL+++ ++ + TP A H +A Sbjct: 321 VRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVA 354 Score = 30.8 bits (68), Expect = 7.3 Identities = 18/62 (29%), Positives = 32/62 (51%) Query: 136 AAIDAVDNKKNTPLHYAAASGMKACVELLVKHGGDLFAENENKDTPCDCAEKQHHKDLAL 195 A ++A K TPL+ AA V+ L+++G + E+ TP A +Q H+++ Sbjct: 102 ANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVA 161 Query: 196 NL 197 +L Sbjct: 162 HL 163 >gi|70780355 ankyrin 1 isoform 2 [Homo sapiens] Length = 1719 Score = 51.2 bits (121), Expect = 5e-06 Identities = 39/151 (25%), Positives = 66/151 (43%), Gaps = 6/151 (3%) Query: 46 HNTPLHYAARHGMNKILGTFLGRDGNPNKRNVHNETSMHLLCMGPQIMISEGALH--PRL 103 H TPLH AA G +++ L + PN R ++ T +H+ C + + E L + Sbjct: 338 HLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASI 397 Query: 104 ARPTEDDFRRADCLQMILKWKGAKLDQGEYERAAIDAVDN-KKNTPLHYAAASGMKACVE 162 TE L + + + +R A V N K TPLH AA +G + Sbjct: 398 DAVTESGLTP---LHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAK 454 Query: 163 LLVKHGGDLFAENENKDTPCDCAEKQHHKDL 193 L+++ + A+ ++ TP CA + H ++ Sbjct: 455 YLLQNKAKVNAKAKDDQTPLHCAARIGHTNM 485 Score = 43.9 bits (102), Expect = 8e-04 Identities = 47/188 (25%), Positives = 81/188 (43%), Gaps = 24/188 (12%) Query: 39 SYGEPYQHNTP-LHYAARHGMNKILGTFLGRDGNPNKRNVHNETSMHLLCMGP-----QI 92 +YG + P LH AAR+ + L D NP+ + T +H+ Q+ Sbjct: 165 NYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQL 224 Query: 93 MISEGA---LHPRLA-RPTEDDFRRADCLQMILKWKGAKLDQGEYERAAIDAVDNKKNTP 148 +++ GA P+ P RR + + + L LD+G A I+ + TP Sbjct: 225 LLNRGASVNFTPQNGITPLHIASRRGNVIMVRLL-----LDRG----AQIETKTKDELTP 275 Query: 149 LHYAAASGMKACVELLVKHGGDLFAENENKDTPCDCAEKQHHKDLALNLESQMVFSRDPE 208 LH AA +G E+L+ HG + A+ +N +P A + H D +++ D E Sbjct: 276 LHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCV-----RLLLQYDAE 330 Query: 209 AEEIEAEY 216 ++I ++ Sbjct: 331 IDDITLDH 338 Score = 43.9 bits (102), Expect = 8e-04 Identities = 41/153 (26%), Positives = 62/153 (40%), Gaps = 6/153 (3%) Query: 48 TPLHYAARHGMNKILGTFLGRDGNPNKRNVHNETSMHLLCMGPQIMISEGALHPRLARP- 106 TPLH AAR G ++ L + NPN T +H+ + L ++ Sbjct: 472 TPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQAC 531 Query: 107 -TEDDFRRADCLQMILKWKGAKLDQGEYERAAIDAVDNKKN-TPLHYAAASGMKACVELL 164 T+ F L + K+ ++ + ER A K TPLH A V+LL Sbjct: 532 MTKKGFTP---LHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLL 588 Query: 165 VKHGGDLFAENENKDTPCDCAEKQHHKDLALNL 197 + GG + N TP A KQ+ ++A +L Sbjct: 589 LPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSL 621 Score = 43.1 bits (100), Expect = 0.001 Identities = 41/182 (22%), Positives = 71/182 (39%), Gaps = 35/182 (19%) Query: 14 NGDENLACQIYENNPQLKESLDP--NTSYGEPYQHNTPLHYAARHGMNKILGTFLGRDGN 71 NG L +N ++ SL ++ E Q TPLH AA+ G +++ L + N Sbjct: 601 NGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQAN 660 Query: 72 PNKRNVHNETSMHLLCMGPQIMISEGALHPRLARPTEDDFRRADCLQMILKWKGAKLDQG 131 N N T +HL+ + +++ +++K Sbjct: 661 GNLGNKSGLTPLHLVAQEGHVPVAD----------------------VLIK--------- 689 Query: 132 EYERAAIDAVDNKKNTPLHYAAASGMKACVELLVKHGGDLFAENENKDTPCDCAEKQHHK 191 +DA TPLH A+ G V+ L++H D+ A+ + +P A +Q H Sbjct: 690 --HGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHT 747 Query: 192 DL 193 D+ Sbjct: 748 DI 749 Score = 42.4 bits (98), Expect = 0.002 Identities = 41/153 (26%), Positives = 65/153 (42%), Gaps = 12/153 (7%) Query: 48 TPLHYAARHGMNKILGTFLGRDGNPNKRNVHNETSMHLLCMGPQIMISEGALHPRLARPT 107 TPLH AA++G ++ L RD +PN + T +H+ + I + L PR P Sbjct: 538 TPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVK-LLLPRGGSPH 596 Query: 108 EDDFRRADCLQMILKWKGAKLDQGEYERAAI------DAVDNKKNTPLHYAAASGMKACV 161 + L + AK +Q E R+ + +A + TPLH AA G V Sbjct: 597 SPAWNGYTPLHI-----AAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMV 651 Query: 162 ELLVKHGGDLFAENENKDTPCDCAEKQHHKDLA 194 LL+ + N++ TP ++ H +A Sbjct: 652 ALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVA 684 Score = 36.6 bits (83), Expect = 0.13 Identities = 38/159 (23%), Positives = 60/159 (37%), Gaps = 22/159 (13%) Query: 43 PYQHNTPLHYAARHGMNKILGTFLGRDGNPNKRNVHNETSMHLLCMGPQIMISEGALH-- 100 P TPLH A+R G ++ L R + T +H + ISE L Sbjct: 236 PQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHG 295 Query: 101 PRLARPTEDDFR---------RADCLQMILKWKGAKLDQGEYERAAIDAVDNKKNTPLHY 151 + T++ DC++++L++ A ID + TPLH Sbjct: 296 APIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYD-----------AEIDDITLDHLTPLHV 344 Query: 152 AAASGMKACVELLVKHGGDLFAENENKDTPCDCAEKQHH 190 AA G ++L+ G + N TP A K++H Sbjct: 345 AAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNH 383 Score = 36.2 bits (82), Expect = 0.17 Identities = 17/61 (27%), Positives = 33/61 (54%) Query: 133 YERAAIDAVDNKKNTPLHYAAASGMKACVELLVKHGGDLFAENENKDTPCDCAEKQHHKD 192 ++ ++ K NT LH AA +G V LV +G ++ A+++ TP A +++H + Sbjct: 66 HKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLE 125 Query: 193 L 193 + Sbjct: 126 V 126 Score = 31.2 bits (69), Expect = 5.6 Identities = 35/154 (22%), Positives = 61/154 (39%), Gaps = 14/154 (9%) Query: 48 TPLHYAARHGMNKILGTFLGRDGNPNKRNVHNETSMHLLC-----MGPQIMISEGALHPR 102 TPLH AA + + L R + N + T +H+ + ++++ GA + Sbjct: 208 TPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGA---Q 264 Query: 103 LARPTEDDFRRADCLQMI--LKWKGAKLDQGEYERAAIDAVDNKKNTPLHYAAASGMKAC 160 + T+D+ C ++ LD G A I A +P+H AA C Sbjct: 265 IETKTKDELTPLHCAARNGHVRISEILLDHG----APIQAKTKNGLSPIHMAAQGDHLDC 320 Query: 161 VELLVKHGGDLFAENENKDTPCDCAEKQHHKDLA 194 V LL+++ ++ + TP A H +A Sbjct: 321 VRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVA 354 Score = 30.8 bits (68), Expect = 7.3 Identities = 18/62 (29%), Positives = 32/62 (51%) Query: 136 AAIDAVDNKKNTPLHYAAASGMKACVELLVKHGGDLFAENENKDTPCDCAEKQHHKDLAL 195 A ++A K TPL+ AA V+ L+++G + E+ TP A +Q H+++ Sbjct: 102 ANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVA 161 Query: 196 NL 197 +L Sbjct: 162 HL 163 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.315 0.131 0.400 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 46,296,531 Number of Sequences: 37866 Number of extensions: 2300957 Number of successful extensions: 10636 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 309 Number of HSP's successfully gapped in prelim test: 178 Number of HSP's that attempted gapping in prelim test: 8689 Number of HSP's gapped (non-prelim): 1638 length of query: 1089 length of database: 18,247,518 effective HSP length: 113 effective length of query: 976 effective length of database: 13,968,660 effective search space: 13633412160 effective search space used: 13633412160 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.