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Search of human proteins with 148235600
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|148235600 nucleolar protein 4 [Homo sapiens]
(638 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|148235600 nucleolar protein 4 [Homo sapiens] 1269 0.0
gi|193788697 hypothetical protein LOC140688 [Homo sapiens] 394 e-109
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 59 1e-08
gi|20270337 Leo1, Paf1/RNA polymerase II complex component, homo... 47 5e-05
gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precu... 43 8e-04
gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2 pre... 43 8e-04
gi|122937247 unc-13 homolog A [Homo sapiens] 43 0.001
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 42 0.002
gi|115529449 upstream binding transcription factor, RNA polymera... 40 0.007
gi|115529451 upstream binding transcription factor, RNA polymera... 40 0.007
gi|7657671 upstream binding transcription factor, RNA polymerase... 40 0.007
gi|148612801 KIAA1009 protein [Homo sapiens] 40 0.007
gi|57864582 hornerin [Homo sapiens] 39 0.011
gi|55741677 SET domain containing 1A [Homo sapiens] 39 0.011
gi|197245440 hypothetical protein LOC23285 [Homo sapiens] 39 0.011
gi|19526767 MLK-related kinase isoform 2 [Homo sapiens] 39 0.015
gi|16445033 ACRC protein [Homo sapiens] 39 0.019
gi|151301053 RNA binding motif protein 33 [Homo sapiens] 38 0.025
gi|46195755 SCAN domain containing 3 [Homo sapiens] 38 0.025
gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo... 38 0.025
gi|210032580 SET domain containing 1B [Homo sapiens] 38 0.033
gi|56711320 hypothetical protein LOC145407 [Homo sapiens] 38 0.033
gi|4504487 histidine rich calcium binding protein precursor [Hom... 37 0.043
gi|195976782 Paf1/RNA polymerase II complex component [Homo sapi... 37 0.043
gi|24308089 chromodomain helicase DNA binding protein 5 [Homo sa... 37 0.043
gi|68299795 chromodomain helicase DNA binding protein 1 [Homo sa... 37 0.056
gi|47106061 KRAB-A domain containing 2 [Homo sapiens] 36 0.095
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 36 0.12
gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens] 36 0.12
gi|55749769 CWC22 spliceosome-associated protein homolog [Homo s... 36 0.12
>gi|148235600 nucleolar protein 4 [Homo sapiens]
Length = 638
Score = 1269 bits (3285), Expect = 0.0
Identities = 638/638 (100%), Positives = 638/638 (100%)
Query: 1 MESERDMYRQFQDWCLRTYGDSGKTKTVTRKKYERIVQLLNGSESSSTDNAKFKFWVKSK 60
MESERDMYRQFQDWCLRTYGDSGKTKTVTRKKYERIVQLLNGSESSSTDNAKFKFWVKSK
Sbjct: 1 MESERDMYRQFQDWCLRTYGDSGKTKTVTRKKYERIVQLLNGSESSSTDNAKFKFWVKSK 60
Query: 61 GFQLGQPDEVRGGGGGAKQVLYVPVKTTDGVGVDEKLSLRRVAVVEDFFDIIYSMHVETG 120
GFQLGQPDEVRGGGGGAKQVLYVPVKTTDGVGVDEKLSLRRVAVVEDFFDIIYSMHVETG
Sbjct: 61 GFQLGQPDEVRGGGGGAKQVLYVPVKTTDGVGVDEKLSLRRVAVVEDFFDIIYSMHVETG 120
Query: 121 PNGEQIRKHAGQKRTYKAISESYAFLPREAVTRFLMSCSECQKRMHLNPDGTDHKDNGKP 180
PNGEQIRKHAGQKRTYKAISESYAFLPREAVTRFLMSCSECQKRMHLNPDGTDHKDNGKP
Sbjct: 121 PNGEQIRKHAGQKRTYKAISESYAFLPREAVTRFLMSCSECQKRMHLNPDGTDHKDNGKP 180
Query: 181 PTLVTSMIDYNMPITMAYMKHMKLQLLNSQQDEDESSIESDEFDMSDSTRMSAVNSDLSS 240
PTLVTSMIDYNMPITMAYMKHMKLQLLNSQQDEDESSIESDEFDMSDSTRMSAVNSDLSS
Sbjct: 181 PTLVTSMIDYNMPITMAYMKHMKLQLLNSQQDEDESSIESDEFDMSDSTRMSAVNSDLSS 240
Query: 241 NLEERMQSPQNLHGQQDDDSAAESFNGNETLGHSSIASGGTHSREMGDSNSDGKTGLEQD 300
NLEERMQSPQNLHGQQDDDSAAESFNGNETLGHSSIASGGTHSREMGDSNSDGKTGLEQD
Sbjct: 241 NLEERMQSPQNLHGQQDDDSAAESFNGNETLGHSSIASGGTHSREMGDSNSDGKTGLEQD 300
Query: 301 EQPLNLSDSPLSAQLTSEYRIDDHNSNGKNKYKNLLISDLKMEREARENGSKSPAHSYSS 360
EQPLNLSDSPLSAQLTSEYRIDDHNSNGKNKYKNLLISDLKMEREARENGSKSPAHSYSS
Sbjct: 301 EQPLNLSDSPLSAQLTSEYRIDDHNSNGKNKYKNLLISDLKMEREARENGSKSPAHSYSS 360
Query: 361 YDSGKNESVDRGAEDLSLNRGDEDEDDHEDHDDSEKVNETDGVEAERLKAFNMFVRLFVD 420
YDSGKNESVDRGAEDLSLNRGDEDEDDHEDHDDSEKVNETDGVEAERLKAFNMFVRLFVD
Sbjct: 361 YDSGKNESVDRGAEDLSLNRGDEDEDDHEDHDDSEKVNETDGVEAERLKAFNMFVRLFVD 420
Query: 421 ENLDRMVPISKQPKEKIQAIIDSCRRQFPEYQERARKRIRTYLKSCRRMKRSGFEMSRPI 480
ENLDRMVPISKQPKEKIQAIIDSCRRQFPEYQERARKRIRTYLKSCRRMKRSGFEMSRPI
Sbjct: 421 ENLDRMVPISKQPKEKIQAIIDSCRRQFPEYQERARKRIRTYLKSCRRMKRSGFEMSRPI 480
Query: 481 PSHLTSAVAESILASACESESRNAAKRMRLERQQDESAPADKQCKPEATQATYSTSAVPG 540
PSHLTSAVAESILASACESESRNAAKRMRLERQQDESAPADKQCKPEATQATYSTSAVPG
Sbjct: 481 PSHLTSAVAESILASACESESRNAAKRMRLERQQDESAPADKQCKPEATQATYSTSAVPG 540
Query: 541 SQDVLYINGNGTYSYHSYRGLGGGLLNLNDASSSGPTDLSMKRQLATSSGSSSSSNSRPQ 600
SQDVLYINGNGTYSYHSYRGLGGGLLNLNDASSSGPTDLSMKRQLATSSGSSSSSNSRPQ
Sbjct: 541 SQDVLYINGNGTYSYHSYRGLGGGLLNLNDASSSGPTDLSMKRQLATSSGSSSSSNSRPQ 600
Query: 601 LSPTEINAVRQLVAGYRESAAFLLRSADELENLILQQN 638
LSPTEINAVRQLVAGYRESAAFLLRSADELENLILQQN
Sbjct: 601 LSPTEINAVRQLVAGYRESAAFLLRSADELENLILQQN 638
>gi|193788697 hypothetical protein LOC140688 [Homo sapiens]
Length = 436
Score = 394 bits (1013), Expect = e-109
Identities = 245/451 (54%), Positives = 304/451 (67%), Gaps = 52/451 (11%)
Query: 225 MSDSTRMSA---VNSDLSSNLEERMQSPQNLHGQQDDDSAAESFNGNETLGHSSIASGGT 281
MSDST MSA + S LS + +ERM+SPQNLH Q+DDDS++ES +GN SS + T
Sbjct: 1 MSDSTWMSADPHLASSLSPSQDERMRSPQNLHSQEDDDSSSESGSGNG----SSTLNPST 56
Query: 282 HSREMGDS-----NSDGKTG-----LEQDEQPLNLSDS--PLSAQLTSEYRIDDHNSNGK 329
S GD N +G ++QP+NL D P +A T+ Y D ++G
Sbjct: 57 SSSTQGDPAFPEMNGNGAVAPMDFTTAAEDQPINLCDKLPPATALGTASYPSDGCGADG- 115
Query: 330 NKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVDRGAEDLSLNRG---DEDED 386
L S +K + +SP +S SYDS K E V EDL++ R D+D+D
Sbjct: 116 ------LRSRVKY---GVKTTPESPPYSSGSYDSIKTE-VSGCPEDLTVGRAPTADDDDD 165
Query: 387 DHEDHDDSEKVNETDGVEAERLKAFNMFVRLFVDENLDRMVPISKQPKEKIQAIIDSCRR 446
DH+DH+D++K+N+++G++ ERLKAFNMFVRLFVDENLDRMVPISKQPKEKIQAII+SC R
Sbjct: 166 DHDDHEDNDKMNDSEGMDPERLKAFNMFVRLFVDENLDRMVPISKQPKEKIQAIIESCSR 225
Query: 447 QFPEYQERARKRIRTYLKSCRRMKRSGFEMSRPIPSHLTSAVAESILASACESESRNAAK 506
QFPE+QERARKRIRTYLKSCRRMK++G EM+RP P HLTSA+AE+ILA+ACESE+R AAK
Sbjct: 226 QFPEFQERARKRIRTYLKSCRRMKKNGMEMTRPTPPHLTSAMAENILAAACESETRKAAK 285
Query: 507 RMRLE---RQQDESAPADKQCKPEATQATYSTSAVPG---SQDVLYINGNGTYSYHSYRG 560
RMRLE QDE DKQ ++ T+ST ++P SQD +Y NG YSY Y
Sbjct: 286 RMRLEIYQSSQDEPIALDKQHSRDSAAITHSTYSLPASSYSQDPVYANGGLNYSYRGYGA 345
Query: 561 LGGGL---LNLNDAS-SSGPTDLSMKRQLATSSGS-----SSSSNSRP----QLSPTEIN 607
L L +L + S+GPTDLSMK +T+S + SS+S SRP QLSPTEI+
Sbjct: 346 LSSNLQPPASLQTGNHSNGPTDLSMKGGASTTSTTPTPTPSSTSTSRPVPTAQLSPTEIS 405
Query: 608 AVRQLVAGYRESAAFLLRSADELENLILQQN 638
AVRQL+AGYRESAAFLLRSADELENLILQQN
Sbjct: 406 AVRQLIAGYRESAAFLLRSADELENLILQQN 436
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 58.9 bits (141), Expect = 1e-08
Identities = 49/193 (25%), Positives = 74/193 (38%), Gaps = 2/193 (1%)
Query: 208 NSQQDEDESSIESDEFDMSDSTRMSAVNSDLSSNLEERMQSPQNLHGQQDDDSAAESFNG 267
+ + +SS SD D SDS+ + NS SSN + S + DS+ S +
Sbjct: 795 SDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSD 854
Query: 268 NETLGHSSIASGGTHSREMGDSNSDGKTGLEQDEQPLNLSDSPLSAQLTSEYRIDDHNSN 327
+ SS +S + S + SNS + + N SDS S+ + D NS+
Sbjct: 855 SSNRSDSSNSSDSSDSSD--SSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSS 912
Query: 328 GKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVDRGAEDLSLNRGDEDEDD 387
+ N S N S S S SS S + S D S N D + +
Sbjct: 913 DSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSN 972
Query: 388 HEDHDDSEKVNET 400
D DS +++
Sbjct: 973 SSDSSDSSNSSDS 985
Score = 57.4 bits (137), Expect = 4e-08
Identities = 48/199 (24%), Positives = 77/199 (38%), Gaps = 10/199 (5%)
Query: 208 NSQQDEDESSIESDEFDMSDSTRMSAVNSDLSSNLEERMQSPQNLHGQQDDDSAAESFNG 267
N D D+S + D SDS + NS SS+ + S N D + S +
Sbjct: 532 NGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSS 591
Query: 268 NETLGHSSIASGGTHSREMGDSNSDGKTGLEQDEQPLNLSDSPLSAQLTSEYRIDDHNSN 327
+ SS +S + S + DS+ + + + + SDS S+ + D +SN
Sbjct: 592 DSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSS-----DSDSKSDSSDSN 646
Query: 328 GKNKYKNLLISDLKMEREARENG-----SKSPAHSYSSYDSGKNESVDRGAEDLSLNRGD 382
+ N SD + ++ S S + S SS S ++S D S + D
Sbjct: 647 SSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSD 706
Query: 383 EDEDDHEDHDDSEKVNETD 401
+ D D DS N +D
Sbjct: 707 SSDSDSSDSSDSSNSNSSD 725
Score = 56.2 bits (134), Expect = 9e-08
Identities = 50/204 (24%), Positives = 86/204 (42%), Gaps = 17/204 (8%)
Query: 208 NSQQDEDESSIESDEFDMSDSTRMSAVNSDLSSNLEERMQSPQNLHGQQDDDSAAESFNG 267
+S D +SS SD D SDS+ +SD S + + + S ++ D DS ++S +
Sbjct: 590 SSDSDSSDSSNSSDSSDSSDSSD----SSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDS 645
Query: 268 NET----------LGHSSIASGGTHSREMGDSNSDGKTGLEQDEQPLNLSDSPLSAQLTS 317
N + +SS +S + S + DS+S + D + SDS S++ +
Sbjct: 646 NSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSS--DSSDSSNSSESSD 703
Query: 318 EYRIDDHNSNGKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVDRGAEDLS 377
D +S+ + N SD + + S + + S S DS N S + D S
Sbjct: 704 SSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDS-SNSSDSSDSSDSS 762
Query: 378 LNRGDEDEDDHEDHDDSEKVNETD 401
+ D D D DS ++++
Sbjct: 763 NSSDSSDSSDSSDSSDSSNSSDSN 786
Score = 55.8 bits (133), Expect = 1e-07
Identities = 53/199 (26%), Positives = 76/199 (38%), Gaps = 6/199 (3%)
Query: 208 NSQQDEDESSIESDEFDMSDSTRMSAVNSDLSSNLEERMQSPQNLHGQQDDDSAAESFNG 267
++ D +SS SD SDS+ S+ +SD S + S + D +++S N
Sbjct: 663 SNSSDSSDSSDSSDSSSSSDSSN-SSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNS 721
Query: 268 NETLGHSSIASGGTHSREMGDS--NSDGKTGLEQDEQPLNLSDSPLSAQLTSEYRIDDHN 325
N + SS +S + S DS +SD + + + + S S S D N
Sbjct: 722 NSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSN 781
Query: 326 SNGKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVDRGAEDL--SLNRGD- 382
S+ N N S N S S S SS N S + D S N D
Sbjct: 782 SSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDS 841
Query: 383 EDEDDHEDHDDSEKVNETD 401
D D D DS+ N +D
Sbjct: 842 SDSSDSSDGSDSDSSNRSD 860
Score = 53.5 bits (127), Expect = 6e-07
Identities = 51/203 (25%), Positives = 81/203 (39%), Gaps = 11/203 (5%)
Query: 208 NSQQDEDESSIESDEFDMSDS-TRMSAVNSDLSSNLEERMQSPQNLHGQQDDDSAAESFN 266
+ D +SS SD D SDS + S SD S + + S N D+ +++S N
Sbjct: 602 SDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSN 661
Query: 267 GNET--------LGHSSIASGGTHSREMGDSNSDGKTGLEQDEQPLNLSDSPLSAQLTSE 318
+ + SS +S ++S + DS+ + D + SDS S+ ++
Sbjct: 662 SSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNS 721
Query: 319 YRIDDHNSNGKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVDRGAEDLSL 378
D +SN + + SD + N S S S SS S ++S D S
Sbjct: 722 NSSDSDSSNSSDSSDSSNSSD-SSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSS 780
Query: 379 NRGDEDEDDHEDHDDSEKVNETD 401
N D + D D S+ N +D
Sbjct: 781 NSSDSN-DSSNSSDSSDSSNSSD 802
Score = 53.1 bits (126), Expect = 8e-07
Identities = 55/201 (27%), Positives = 83/201 (41%), Gaps = 18/201 (8%)
Query: 208 NSQQDEDESSIESDEFDMSDSTRMS--AVNSDLSSNLEERMQSPQNLHGQQDDDSAAESF 265
+ D +SS SD D SDS+ S + +SD S + + S N D S +S
Sbjct: 741 SDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSS--DSS 798
Query: 266 NGNETLGHSSIASGGTHSREMGDSNSDGKTGLEQDEQPLNLSDSPLSAQLTSEYRIDDHN 325
N +++ +SS +S + S + SNS + N SDS S+ + D +
Sbjct: 799 NSSDS-SNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSS-----DGSD 852
Query: 326 SNGKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVDRGAEDLSLNRGDEDE 385
S+ N+ + SD + S S S SS S NES + S N D D
Sbjct: 853 SDSSNRSDSSNSSD-------SSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDS 905
Query: 386 DDHED-HDDSEKVNETDGVEA 405
D + D S+ N +D E+
Sbjct: 906 SDSSNSSDSSDSSNSSDSSES 926
Score = 53.1 bits (126), Expect = 8e-07
Identities = 54/205 (26%), Positives = 79/205 (38%), Gaps = 14/205 (6%)
Query: 208 NSQQDEDESSIESDEFD--MSDSTRMS----AVNSDLSSNLEERMQSPQNLHGQQDDDSA 261
++ D SS SD D SDS+ S + +S SSN + S + G D S
Sbjct: 798 SNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSN 857
Query: 262 AESFNGNETLGHSSIASGGTHSREMGDSNSDGKTGLEQDEQPLNLSDSPLSAQLTSEYRI 321
+ + SS +S + S + DSN + D N SDS S S
Sbjct: 858 RSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSS--NSSDSDSSDSSNSSDSS 915
Query: 322 DDHNSN----GKNKYKNLLISDLKMEREARE--NGSKSPAHSYSSYDSGKNESVDRGAED 375
D NS+ N N SD ++ + + S S S SS S ++S D + D
Sbjct: 916 DSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSD 975
Query: 376 LSLNRGDEDEDDHEDHDDSEKVNET 400
S + D D D DS +++
Sbjct: 976 SSDSSNSSDSSDSSDSSDSSDSSDS 1000
Score = 52.4 bits (124), Expect = 1e-06
Identities = 42/200 (21%), Positives = 82/200 (41%), Gaps = 3/200 (1%)
Query: 208 NSQQDEDESSIESDEFDMSDSTRMSAVNSDLSSNLEERMQSPQNLHGQQDDDSAAESFNG 267
+ D +SS S+ D SDS+ + +S SSN N D ++++S +
Sbjct: 687 SDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDS 746
Query: 268 NETLGHSSIASGGTHSREMGDSNSDGKTGLEQDEQPLNLSDSPLSAQLTSEYRIDDHNSN 327
+++ +SS +S + S DS+ + D + S+ ++ +S+ +SN
Sbjct: 747 SDS-SNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSN 805
Query: 328 GKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVDRGAEDLSLNRGDEDE-- 385
+ + SD + + S + S +S DS + G++ S NR D
Sbjct: 806 SSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSS 865
Query: 386 DDHEDHDDSEKVNETDGVEA 405
D + D S + +D ++
Sbjct: 866 DSSDSSDSSNSSDSSDSSDS 885
Score = 52.0 bits (123), Expect = 2e-06
Identities = 45/193 (23%), Positives = 78/193 (40%), Gaps = 5/193 (2%)
Query: 208 NSQQDEDESSIESDEFDMSDSTRMSAVNSDLSSNLEERMQSPQNLHGQQDDDSAAESFNG 267
+S + SS +SD D SDS+ S +S SSN + S + DS+ +
Sbjct: 568 DSDSSDSNSSSDSDSSD-SDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDS 626
Query: 268 NETLGHSSIASGGTHSREMGDSNSDGKTGLEQDEQPLNLSDSPLSAQLTSEYRIDDHNSN 327
+++ SS + + S + S+S + N SDS S S+ +S+
Sbjct: 627 SKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDS----SDSSDSSSSSD 682
Query: 328 GKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVDRGAEDLSLNRGDEDEDD 387
N + SD E+ ++ S + S S DS + S D + + S + + D
Sbjct: 683 SSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSD 742
Query: 388 HEDHDDSEKVNET 400
D DS +++
Sbjct: 743 SSDSSDSSNSSDS 755
Score = 51.2 bits (121), Expect = 3e-06
Identities = 46/200 (23%), Positives = 81/200 (40%), Gaps = 10/200 (5%)
Query: 209 SQQDEDESSIESDEFDMSDSTRMSAVNSDLSSNLEERMQSPQNLHGQQDDDSAAESFNGN 268
S+ D +S +SD D + S +S SSN S + D S+++S N +
Sbjct: 629 SESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDS-SDSSDSSSSSDSSNSS 687
Query: 269 ETLGHSSIASGGTHSREMGDS-------NSDGKTGLEQDEQPLNLSDSPLSAQLTSEYRI 321
++ SS +S + S + DS +SD D N SDS S+ +S+
Sbjct: 688 DS-SDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSN-SSDSSD 745
Query: 322 DDHNSNGKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVDRGAEDLSLNRG 381
+SN + + S+ ++ ++ S + + S + N S + + S +
Sbjct: 746 SSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSN 805
Query: 382 DEDEDDHEDHDDSEKVNETD 401
D D D DS+ N +D
Sbjct: 806 SSDSSDSSDSSDSDSSNSSD 825
Score = 50.8 bits (120), Expect = 4e-06
Identities = 48/204 (23%), Positives = 83/204 (40%), Gaps = 14/204 (6%)
Query: 208 NSQQDEDESSIESDEFDMSDSTRMS-AVNSDLSSNLEERMQSPQNLHGQQDDDSAAESFN 266
+ D SS SD D SDS+ S + +S+ SSN + S + DS+ S +
Sbjct: 756 SDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDS 815
Query: 267 GNETLGHSSIASGGTHSREMGDS-----NSDGKTGLEQDEQPLNLSDSPLSAQLT----S 317
+ +SS +S + S + +S +SD G + D N SDS S+ + S
Sbjct: 816 SDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSS--NRSDSSNSSDSSDSSDS 873
Query: 318 EYRIDDHNSNGKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVDRGAEDLS 377
D +S+ N+ N SD + ++ S ++S S DS + +
Sbjct: 874 SNSSDSSDSSDSNESSN--SSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSD 931
Query: 378 LNRGDEDEDDHEDHDDSEKVNETD 401
+ + + + D S+ N +D
Sbjct: 932 NSNSSDSSNSSDSSDSSDSSNSSD 955
Score = 50.8 bits (120), Expect = 4e-06
Identities = 51/195 (26%), Positives = 83/195 (42%), Gaps = 9/195 (4%)
Query: 208 NSQQDEDESSIESDEFDMSDSTRMSAVNSDLSSNLEERMQSPQNLHGQQDDDSAAESFNG 267
+S + +SS S+ D SDS+ S +S SSN + S + + DS+ +S N
Sbjct: 897 SSNSSDSDSSDSSNSSDSSDSSNSS--DSSESSNSSDNSNSSDSSNSSDSSDSS-DSSNS 953
Query: 268 NETLGHSSIASGGTHSREMGDSNSDGKTGLEQDEQPLNLSDSPLSAQLT-SEYRIDDHNS 326
++ SS +S ++S + DSNS + + SDS S+ + S D +S
Sbjct: 954 SD----SSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDS 1009
Query: 327 NGKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVD-RGAEDLSLNRGDEDE 385
+ + N S + + S S S SS S ++S D + D S + D
Sbjct: 1010 SDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDS 1069
Query: 386 DDHEDHDDSEKVNET 400
D D DS +E+
Sbjct: 1070 SDSSDSSDSSDSSES 1084
Score = 50.4 bits (119), Expect = 5e-06
Identities = 44/200 (22%), Positives = 78/200 (39%), Gaps = 8/200 (4%)
Query: 208 NSQQDEDESSIESDEFDMSDSTRMSAVNSDLSSNLEERMQSPQNLHGQQDDDSAAESFNG 267
+ + +SS SD D SDS+ S+ +SD S + E S + D +++S N
Sbjct: 853 SDSSNRSDSSNSSDSSDSSDSSN-SSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNS 911
Query: 268 NETLGHSSIASGGTHSREMGDSN---SDGKTGLEQDEQPLNLSDSPLSAQLTSEYRIDDH 324
+++ S+ + S +SN S + N SDS S+ ++ D
Sbjct: 912 SDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDS 971
Query: 325 NSNGKNKYKNLL----ISDLKMEREARENGSKSPAHSYSSYDSGKNESVDRGAEDLSLNR 380
NS+ + N SD ++ ++ + S + S N S + D S +
Sbjct: 972 NSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSS 1031
Query: 381 GDEDEDDHEDHDDSEKVNET 400
D D D DS +++
Sbjct: 1032 DSSDSSDSSDSSDSSDSSDS 1051
Score = 50.4 bits (119), Expect = 5e-06
Identities = 49/201 (24%), Positives = 79/201 (39%), Gaps = 13/201 (6%)
Query: 208 NSQQDEDESSIESDEFDMSDSTRMSAVNSDLSSNLEERMQSPQNLHGQQDDDSAAESFNG 267
+ D +ESS SD D S+S+ + +S SS+ + S + D++ S +
Sbjct: 880 SDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSS 939
Query: 268 NETLGHSSIASGGTHSREMGDSNSDGKTGLEQDEQPLNLSDSPLSAQLT-SEYRIDDHNS 326
N SS +S + S DS++ + D N SDS S+ + S D +S
Sbjct: 940 N-----SSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDS 994
Query: 327 NGKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVDRG-------AEDLSLN 379
+ + N S + N S S S SS S ++S D + D S +
Sbjct: 995 SDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDS 1054
Query: 380 RGDEDEDDHEDHDDSEKVNET 400
D D D DS +++
Sbjct: 1055 SNSSDSSDSSDSSDSSDSSDS 1075
Score = 50.1 bits (118), Expect = 6e-06
Identities = 46/189 (24%), Positives = 80/189 (42%), Gaps = 20/189 (10%)
Query: 212 DEDESSIESDEFDMSDSTRMSAVNSDLSSNLEERMQSPQNLHGQQDDDSAAESFNGNETL 271
D D+ S++ D+ + SD + N + +N E S + D + ++ NG+++
Sbjct: 454 DFDDKSMQGDDPNSSDES-----NGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSK 508
Query: 272 GHSSIASGGTHSREMGDSNSDGKTGLEQDEQPLNLSDSPLSAQLTSEYRIDDHNSNGKNK 331
G S T DSN +G G + +++ SDS +S D +S+ N
Sbjct: 509 GAEDDDSDSTSDTNNSDSNGNGNNGNDDNDK----SDSGKGKSDSS----DSDSSDSSNS 560
Query: 332 YKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVDRGAEDLSLNRGDEDEDDHEDH 391
SD ++ + S S + S SS DS ++S D + D S + D D D
Sbjct: 561 ------SDSSDSSDSDSSDSNSSSDSDSS-DSDSSDSSDSDSSDSSNSSDSSDSSDSSDS 613
Query: 392 DDSEKVNET 400
DS +++
Sbjct: 614 SDSSDSSDS 622
Score = 50.1 bits (118), Expect = 6e-06
Identities = 47/194 (24%), Positives = 83/194 (42%), Gaps = 5/194 (2%)
Query: 208 NSQQDEDESSIESDEFDMSDSTRMSAVNSDLSSNLEERMQSPQNLHGQQDDDSAAESFNG 267
+ D +S+ S+ D SDS+ S +S SSN + S N + +++++ N
Sbjct: 877 SDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDS-SNSSDSSESSNSSDNSNS 935
Query: 268 NETLGHSSIASGGTHSREMGDSNSDGKTGLEQDEQPLNLSDSPLSAQLT-SEYRIDDHNS 326
+++ +SS +S + S DS++ + D N SDS S+ + S D +S
Sbjct: 936 SDS-SNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDS 994
Query: 327 NGKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVDRGAEDLSLNRGDEDED 386
+ + N S + N S S S SS S ++S D + D S + D
Sbjct: 995 SDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSD--SSDSSDSSDSSDSS 1052
Query: 387 DHEDHDDSEKVNET 400
D + DS +++
Sbjct: 1053 DSSNSSDSSDSSDS 1066
Score = 49.7 bits (117), Expect = 8e-06
Identities = 86/383 (22%), Positives = 146/383 (38%), Gaps = 47/383 (12%)
Query: 216 SSIESDEFDMSDSTRMSAVNSDLSSNLEERMQSPQNLHGQQDDDSAAESFNGNETLGHSS 275
S SD +D D S D +S+ E +DD+ +ES N + + G +S
Sbjct: 443 SDSNSDGYDSYDFDDKSMQGDDPNSSDESN----------GNDDANSESDNNSSSRGDAS 492
Query: 276 IASGGTHSREMGDSNSDGKTGLEQDEQPLNLSDSPLSAQLTSEYRIDDHNSNGKNKYKNL 335
S S++ G + SD K G E D+ SDS TS+ D N NG N +
Sbjct: 493 YNS--DESKDNG-NGSDSK-GAEDDD-----SDS------TSDTNNSDSNGNGNNGNDDN 537
Query: 336 LISDL-KMEREARENGSKSPAHSYSSYDSGKNESVDRGAEDLSLNRGDEDEDDHEDHDDS 394
SD K + ++ ++ S ++S S DS ++S D + S + D D D D D S
Sbjct: 538 DKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDS-DSSDSDSSDSSDSDSS 596
Query: 395 EKVNETDGVEAERLKAFNMFVRLFVDENLDRMVPISKQPKEKIQAIIDSCRRQFPEYQER 454
+ N +D ++ ++ D S + + DS + + + +
Sbjct: 597 DSSNSSDSSDS--------------SDSSD-----SSDSSDSSDSKSDSSKSE-SDSSDS 636
Query: 455 ARKRIRTYLKSCRRMKRSGFEMSRPIPSHLTSAVAESILASACESESRNAAKRMRLERQQ 514
K + S S S + S+ + S+ S+S N++
Sbjct: 637 DSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSS 696
Query: 515 DESAPADKQCKPEATQATYSTSAVPGSQDVLYINGNGTYSYHSYRGLGGGLLNLNDASSS 574
+ S +D ++ + S S+ S D N + + + + N + SS
Sbjct: 697 NSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSS 756
Query: 575 GPTDLSMKRQLATSSGSSSSSNS 597
+D S + SS SS SS+S
Sbjct: 757 DSSDSSNSSDSSDSSDSSDSSDS 779
Score = 48.9 bits (115), Expect = 1e-05
Identities = 46/200 (23%), Positives = 78/200 (39%), Gaps = 12/200 (6%)
Query: 208 NSQQDEDESSIESDEFDMSDSTRMSAVNSDLSSNLEERMQSPQNLHGQQDDDSAAESFNG 267
+S + S +SD D + S+ + +SD S + + N D +++S +
Sbjct: 557 SSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDS 616
Query: 268 NETLGHSSIASGGTHSREMGDSNSDGKTGLEQDEQPLNLSDSPLSAQLTSEYRIDDHNSN 327
++ SS + + E S+SD K+ D N SDS S S + NS+
Sbjct: 617 SD----SSDSKSDSSKSESDSSDSDSKS----DSSDSNSSDS--SDNSDSSDSSNSSNSS 666
Query: 328 GKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVDRGAEDL--SLNRGDEDE 385
+ + S + + S S S SS S ++S D + D S N D
Sbjct: 667 DSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDS 726
Query: 386 DDHEDHDDSEKVNETDGVEA 405
D D S+ N +D ++
Sbjct: 727 DSSNSSDSSDSSNSSDSSDS 746
Score = 48.5 bits (114), Expect = 2e-05
Identities = 43/193 (22%), Positives = 81/193 (41%), Gaps = 4/193 (2%)
Query: 208 NSQQDEDESSIESDEFDMSDSTRMSAVNSDLSSNLEERMQSPQNLHGQQDDDSAAESFNG 267
+ D SS +D + SDS+ S NS SSN + S + + S + + +
Sbjct: 774 SDSSDSSNSSDSNDSSNSSDSSDSS--NSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSD 831
Query: 268 NETLGHSSIASGGTHSREMGDSNSDGKTGLEQDEQPLNLSDSPLSAQLTSEYRIDDHNSN 327
+ +SS +S + S + DS+S ++ + SDS S+ +S+ + +SN
Sbjct: 832 SSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSD-SSDSSDSNESSN 890
Query: 328 GKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVDRGAEDLSLNRGDEDEDD 387
+ + SD + + S ++S S +S N S + + D S + D D
Sbjct: 891 SSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSES-SNSSDNSNSSDSSNSSDSSDSSD 949
Query: 388 HEDHDDSEKVNET 400
+ DS +++
Sbjct: 950 SSNSSDSSNSSDS 962
Score = 48.5 bits (114), Expect = 2e-05
Identities = 40/200 (20%), Positives = 77/200 (38%), Gaps = 2/200 (1%)
Query: 208 NSQQDEDESSIESDEFDMSDSTRMS-AVNSDLSSNLEERMQSPQNLHGQQDDDSAAESFN 266
++ D ESS SD + SDS+ S + +S SSN + S + + DS + +
Sbjct: 918 SNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSS 977
Query: 267 GNETLGHSSIASGGTHSREMGDS-NSDGKTGLEQDEQPLNLSDSPLSAQLTSEYRIDDHN 325
+ SS +S + S + DS NS + N SDS S+ ++ D +
Sbjct: 978 DSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSS 1037
Query: 326 SNGKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVDRGAEDLSLNRGDEDE 385
+ + + + + S + S S DS + ++ + +
Sbjct: 1038 DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSS 1097
Query: 386 DDHEDHDDSEKVNETDGVEA 405
D + D S+ + +D ++
Sbjct: 1098 DSSDSSDSSDSSDSSDSSDS 1117
Score = 48.1 bits (113), Expect = 2e-05
Identities = 47/194 (24%), Positives = 73/194 (37%), Gaps = 5/194 (2%)
Query: 208 NSQQDEDESSIESDEFDMSDSTRMSAVNSDLSSNLEERMQSPQNLHGQQDDDSAAESFNG 267
+ D +SS SD D SDS S NS SS+ S + D S + + +
Sbjct: 865 SDSSDSSDSSNSSDSSDSSDSNESS--NSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSD 922
Query: 268 NETLGHSSIASGGTHSREMGDSNSDGKTGLEQDEQPLNLSDSPLSAQLTSEYRIDDHNSN 327
+ +SS S + S DS+ + D N SDS S+ + D +S+
Sbjct: 923 SSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSS--NSSDSSNSSDSSDSNSSDSSDSS 980
Query: 328 GKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVDRGAEDLSLNRGDE-DED 386
+ + S + N S S S SS S ++S + S + D D
Sbjct: 981 NSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSS 1040
Query: 387 DHEDHDDSEKVNET 400
D D DS +++
Sbjct: 1041 DSSDSSDSSDSSDS 1054
Score = 48.1 bits (113), Expect = 2e-05
Identities = 42/193 (21%), Positives = 81/193 (41%), Gaps = 5/193 (2%)
Query: 208 NSQQDEDESSIESDEFDMSDSTRMSAVNSDLSSNLEERMQSPQNLHGQQDDDSAAESFNG 267
++ D +SS SD + S+S+ S NS SSN + S + + +S+ S +
Sbjct: 909 SNSSDSSDSSNSSDSSESSNSSDNS--NSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSS 966
Query: 268 NETLGHSSIASGGTHSREMGDSNSDGKTGLEQDEQPLNLSDSPLSAQLTSEYRIDDHNSN 327
+ + +SS +S ++S + DS+ + D N SDS S+ + D +SN
Sbjct: 967 DSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSS--NSSDSSDSSDSSDSSNSSD-SSN 1023
Query: 328 GKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVDRGAEDLSLNRGDEDEDD 387
+ + SD ++ ++ S + S+ + S + D S + D +
Sbjct: 1024 SSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSE 1083
Query: 388 HEDHDDSEKVNET 400
D DS +++
Sbjct: 1084 SSDSSDSSNSSDS 1096
Score = 47.8 bits (112), Expect = 3e-05
Identities = 50/195 (25%), Positives = 77/195 (39%), Gaps = 5/195 (2%)
Query: 208 NSQQDEDESSIESDEFDMSDSTRMSAVNSDLSSNLEERMQSPQNLHGQQDDDSAAESFNG 267
+ D +SS SD D SDS+ S NS SSN + S + DS+ S +
Sbjct: 992 SDSSDSSDSSNSSDSSDSSDSSDSS--NSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSS 1049
Query: 268 NET-LGHSSIASGGTHSREMGDSNSDGKTGLEQDEQPLNLSDSPLSAQLTSEYRIDDHNS 326
+ + +SS +S + S + DS SD + E + S S S D +S
Sbjct: 1050 DSSDSSNSSDSSDSSDSSDSSDS-SDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDS 1108
Query: 327 NGKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVDRG-AEDLSLNRGDEDE 385
+ + + S + + S S S SS S +ES D + D S + D
Sbjct: 1109 SDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDS 1168
Query: 386 DDHEDHDDSEKVNET 400
D D DS +++
Sbjct: 1169 SDSSDSSDSSNSSDS 1183
Score = 47.8 bits (112), Expect = 3e-05
Identities = 45/194 (23%), Positives = 78/194 (40%), Gaps = 9/194 (4%)
Query: 208 NSQQDEDESSIESDEFDMSDSTRMS-AVNSDLSSNLEERMQSPQNLHGQQDDDSAAESFN 266
++ D +SS SD D SDS+ S + NS SS+ + S + DS+ S +
Sbjct: 1028 SNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDS 1087
Query: 267 GNETLGHSSIASGGTHSREMGDSNSDGKTGLEQDEQPLNLSDSPLSAQLTSEYRIDDHNS 326
+ + +SS +S + S + DS+ + D N SDS S+ + +S
Sbjct: 1088 SDSS--NSSDSSDSSDSSDSSDSSDSSDSSDSSDSS--NSSDSSDSSDSSDS----SDSS 1139
Query: 327 NGKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVDRGAEDLSLNRGDEDED 386
N + + SD ++ ++ S + S N S + D S + D
Sbjct: 1140 NSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSS 1199
Query: 387 DHEDHDDSEKVNET 400
D D DS +++
Sbjct: 1200 DSSDSSDSSDSSDS 1213
Score = 47.8 bits (112), Expect = 3e-05
Identities = 50/201 (24%), Positives = 87/201 (43%), Gaps = 9/201 (4%)
Query: 208 NSQQDEDESSIESDEFDMSDSTRMSAVNSDLSSNLEERMQSPQNLHGQQDDDSAAESFNG 267
+ D +SS SD D SDS+ S +S SSN + S + DS+ S +
Sbjct: 1061 SDSSDSSDSSDSSDSSDSSDSSESS--DSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSS 1118
Query: 268 NETLGHSSIASGGTHSREMGD-SNSDGKTGLEQDEQPLNLSDSPLSAQLTSEYRIDDHNS 326
+ + +SS +S + S + D SNS + + + SDS S+ +S+ +S
Sbjct: 1119 DSS--NSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSD-SSDSSDSSDSS 1175
Query: 327 NGKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVDRGAEDLSLNRGDEDE- 385
+ N + SD ++ ++ S + S SS S ++S D S + D +E
Sbjct: 1176 DSSNSSDSSDSSDSSDSSDSSDSSDSSDS-SDSSDSSDSSDSSDSSDSSDSSDSSDSNES 1234
Query: 386 -DDHEDHDDSEKVNETDGVEA 405
D + D S+ N +D ++
Sbjct: 1235 SDSSDSSDSSDSSNSSDSSDS 1255
Score = 47.4 bits (111), Expect = 4e-05
Identities = 66/325 (20%), Positives = 117/325 (36%), Gaps = 19/325 (5%)
Query: 282 HSREMGDSNSDGKTGLEQDEQPLNLSDSPLSAQLTSEYRIDDHNSNGKNKYKNLLISDLK 341
HS DSNSDG + D++ + D S + DD NS N + +
Sbjct: 438 HSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGN---DDANSESDNNSSSRGDASYN 494
Query: 342 MEREARENGSKSPAHSYSSYDSGKNESVDRGAEDLSLNRGDEDED---------DHEDHD 392
+ E+++NG+ S + DS + + + N G++D D D D D
Sbjct: 495 SD-ESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSD 553
Query: 393 DSEKVNETDGVEAERLKAFNMFVRLFVDENLDRMVPISKQPKEKIQAIIDSCRRQFPEYQ 452
S+ N +D ++ + + D + S DS
Sbjct: 554 SSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDS 613
Query: 453 ERARKRIRTYLKSCRRMKRSGFEMSRPIPSHLTSAVAESILASACESESRNAAKRMRLER 512
+ + S + S S+ S S+ + S+ S S N++
Sbjct: 614 SDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSD 673
Query: 513 QQDESAPADKQCKPEATQATYSTSAVPGSQDVLYINGNGTYSYHSYRGLGGGLLNLNDAS 572
D S+ +D +++ ++ S+++ S + + + S S N +D+
Sbjct: 674 SSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNS------NSSDSD 727
Query: 573 SSGPTDLSMKRQLATSSGSSSSSNS 597
SS +D S + SS SS SSNS
Sbjct: 728 SSNSSDSSDSSNSSDSSDSSDSSNS 752
Score = 47.4 bits (111), Expect = 4e-05
Identities = 45/193 (23%), Positives = 79/193 (40%), Gaps = 4/193 (2%)
Query: 208 NSQQDEDESSIESDEFDMSDSTRMSAVNSDLSSNLEERMQSPQNLHGQQDDDSAAESFNG 267
+ + +SS SD D SDS + +S SS+ + S N D + ES N
Sbjct: 833 SDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDS-SNSSDSSDSSDSNESSNS 891
Query: 268 NETLGHSSIASGGTHSREMGDSNSDGKTGLEQDEQPLNLSDSPLSAQLTSEYRIDDHNSN 327
+++ SS +S S S+S + + N SD+ S+ ++ D +S+
Sbjct: 892 SDS-SDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSD-SSD 949
Query: 328 GKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVDRGAEDLSLNRGDEDEDD 387
N + SD ++ ++ S + S +S DS + S + D S + D D
Sbjct: 950 SSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDS-SDSSDSSDSSDSSDSSNSSDSSD 1008
Query: 388 HEDHDDSEKVNET 400
D DS +++
Sbjct: 1009 SSDSSDSSNSSDS 1021
Score = 47.4 bits (111), Expect = 4e-05
Identities = 48/201 (23%), Positives = 78/201 (38%), Gaps = 4/201 (1%)
Query: 208 NSQQDEDESSIESDEFDMSDSTRMSAVNSDLSSNLEERMQSPQNLHGQQDDDSAAESFNG 267
+S D +SS SD D S+S+ S+ +S+ S N S + D S + +
Sbjct: 900 SSDSDSSDSSNSSDSSDSSNSSD-SSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSN 958
Query: 268 NETLGHSSIASGGTHSREMGDSNSDGKTGLEQDEQPLNLSDSPLSAQLT-SEYRIDDHNS 326
+ +SS +S S SNS + + SDS S+ + S D NS
Sbjct: 959 SSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNS 1018
Query: 327 NGKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVDRGAEDLSLNRGD--ED 384
+ + + S + + S S S SS S ++S D S + D +
Sbjct: 1019 SDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDS 1078
Query: 385 EDDHEDHDDSEKVNETDGVEA 405
D E D S+ N +D ++
Sbjct: 1079 SDSSESSDSSDSSNSSDSSDS 1099
Score = 46.6 bits (109), Expect = 7e-05
Identities = 47/201 (23%), Positives = 80/201 (39%), Gaps = 8/201 (3%)
Query: 208 NSQQDEDESSIESDEF-DMSDSTRMSAVNSDLSSNLEERMQSPQNLHGQQDDDSAAESFN 266
N+ ++S SDE D + + D S + + S N +G +D +S +
Sbjct: 483 NNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDS 542
Query: 267 G----NETLGHSSIASGGTHSREMGDSNS-DGKTGLEQDEQPLNLSDSPLSAQLTSEYRI 321
G + + SS +S + S + DS+S D + + D + SDS S S
Sbjct: 543 GKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSS 602
Query: 322 DDHNSNGKNKYKNLL-ISDLKMEREARENGSKSPAHSYSSYDSGKNESVDRG-AEDLSLN 379
D +S+ + + SD K + E+ S S DS ++S D + D S +
Sbjct: 603 DSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNS 662
Query: 380 RGDEDEDDHEDHDDSEKVNET 400
D D D DS +++
Sbjct: 663 SNSSDSSDSSDSSDSSSSSDS 683
Score = 46.6 bits (109), Expect = 7e-05
Identities = 43/193 (22%), Positives = 75/193 (38%), Gaps = 8/193 (4%)
Query: 208 NSQQDEDESSIESDEFDMSDSTRMSAVNSDLSSNLEERMQSPQNLHGQQDDDSAAESFNG 267
+ D +SS SD + SDS+ S + SS+ + S + DS+ S +
Sbjct: 942 SDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSS 1001
Query: 268 NETLGHSSIASGGTHSREMGDSNSDGKTGLEQDEQPLNLSDSPLSAQLTSEYRIDDHNSN 327
N + SS +S + S DS++ + D SDS S+ +S+ +S+
Sbjct: 1002 NSS--DSSDSSDSSDSSNSSDSSNSSDSSNSSDS-----SDSSDSSD-SSDSSDSSDSSD 1053
Query: 328 GKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVDRGAEDLSLNRGDEDEDD 387
N + SD ++ ++ S + S N S + D S + D D
Sbjct: 1054 SSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSD 1113
Query: 388 HEDHDDSEKVNET 400
D DS +++
Sbjct: 1114 SSDSSDSSNSSDS 1126
Score = 46.2 bits (108), Expect = 9e-05
Identities = 49/209 (23%), Positives = 87/209 (41%), Gaps = 13/209 (6%)
Query: 208 NSQQDEDESSIESDEFDMSDSTRMS-------AVNSDLSSNLEERMQSPQNLHGQQDDDS 260
+S D S+ S + D S+S+ S + +S SSN + S + + DS
Sbjct: 711 DSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDS 770
Query: 261 AAESFNGNETLGHSSIASGGTHSREMGD-SNSDGKTGLEQDEQPLNLSDSPLSAQLTSEY 319
+ S + + + +SS ++ ++S + D SNS + + SDS S S
Sbjct: 771 SDSSDSSDSS--NSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSN 828
Query: 320 RIDDHNSNGKNKYKNLLISDLKMEREA--RENGSKSPAHSYSSYDSGKNESVDRGAEDLS 377
D +S+ + + S + ++ R + S S S SS S ++S D + S
Sbjct: 829 SSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNES 888
Query: 378 LNRGD-EDEDDHEDHDDSEKVNETDGVEA 405
N D D + D D S+ N +D ++
Sbjct: 889 SNSSDSSDSSNSSDSDSSDSSNSSDSSDS 917
Score = 45.8 bits (107), Expect = 1e-04
Identities = 55/204 (26%), Positives = 78/204 (38%), Gaps = 27/204 (13%)
Query: 210 QQDEDESSIESDEFD--MSDSTRMSAVNSDLSSNLEERMQSPQ--NLHGQQDDDSAAESF 265
Q D+ SS ES+ D S+S S+ D S N +E + + G +DDDS + S
Sbjct: 461 QGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSD 520
Query: 266 -----------NGNETLGHSSIASGGTHSREMGDSNS----DGKTGLEQDEQPLNLSDSP 310
NGN+ S G + S + S+S D + D N S
Sbjct: 521 TNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDS 580
Query: 311 LSAQLTSEYRIDDHNSNGKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVD 370
S+ S D +S+ N + SD + S S S S DS K+ES D
Sbjct: 581 DSSDSDSSDSSDSDSSDSSNSSDSSDSSD-------SSDSSDSSDSSDSKSDSSKSES-D 632
Query: 371 RGAEDLSLNRGDEDEDDHEDHDDS 394
D + D + D D+ DS
Sbjct: 633 SSDSDSKSDSSDSNSSDSSDNSDS 656
Score = 45.8 bits (107), Expect = 1e-04
Identities = 47/198 (23%), Positives = 80/198 (40%), Gaps = 8/198 (4%)
Query: 208 NSQQDEDESSIESDEFDMSDSTRMSAVNSDLSSNLEERMQSPQNLHGQQDDDSAAESFNG 267
++ D +SS SD D SDS+ S +S SSN + S + DS+ S +
Sbjct: 971 SNSSDSSDSSNSSDSSDSSDSSDSS--DSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSS 1028
Query: 268 NET----LGHSSIASGGTHSREMGDSNSDGKTGLEQDEQPLNLSDSPLSAQLTSEYRIDD 323
N + SS +S + S + DS++ + D + S + +SE
Sbjct: 1029 NSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSS 1088
Query: 324 HNSNGKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVDRGAEDLSLNRGDE 383
+SN + + SD ++ ++ S + S SS S ++S D S + D
Sbjct: 1089 DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDS-SNSSDSSDSSDSSDSSDSSNSSDSSDS 1147
Query: 384 DED-DHEDHDDSEKVNET 400
E D D DS +++
Sbjct: 1148 SESSDSSDSSDSSDSSDS 1165
Score = 45.8 bits (107), Expect = 1e-04
Identities = 49/194 (25%), Positives = 77/194 (39%), Gaps = 6/194 (3%)
Query: 208 NSQQDEDESSIESDEFDMSDSTRMSAVNSDLSSNLEERMQSPQNLHGQQDDDSAAESFNG 267
+ D +SS SD D SDS+ S+ +SD S + + S + D S + +
Sbjct: 1046 SDSSDSSDSSNSSDSSDSSDSSD-SSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSD 1104
Query: 268 NETLGHSSIASGGTHSREMGDSNSDGKTGLEQDEQPLNLSDSPLSAQLT-SEYRIDDHNS 326
+ SS +S + S DS+ + D N SDS S++ + S D +S
Sbjct: 1105 SSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSS--NSSDSSDSSESSDSSDSSDSSDS 1162
Query: 327 NGKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVDRGAEDLSLNRGDEDED 386
+ + + S + S S S SS S ++S D + D S + D
Sbjct: 1163 SDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSD--SSDSSDSSDSSDSS 1220
Query: 387 DHEDHDDSEKVNET 400
D D DS NE+
Sbjct: 1221 DSSDSSDSSDSNES 1234
Score = 45.8 bits (107), Expect = 1e-04
Identities = 44/188 (23%), Positives = 77/188 (40%), Gaps = 3/188 (1%)
Query: 208 NSQQDEDESSIESDEFDMSDSTRMSAVNSDLSSNLEERMQSPQNLHGQQDDDSAAESFNG 267
+ D ESS SD + SDS+ S+ +SD S + + S + D S + +
Sbjct: 1076 SDSSDSSESSDSSDSSNSSDSSD-SSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD 1134
Query: 268 NETLGHSSIASGGTHSREMGDSNSDGKTGLEQDEQPLNLSDSPLSAQLTSEYRIDDHNSN 327
+ +SS +S + S + DS+ + D + S ++ +S+ +S+
Sbjct: 1135 SSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSD 1194
Query: 328 GKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVDRG-AEDLSLNRGDEDED 386
+ + SD ++ ++ S + S SS S NES D + D S + D
Sbjct: 1195 SSDSSDSSDSSDSSDSSDSSDSSDSSDS-SDSSDSSDSNESSDSSDSSDSSDSSNSSDSS 1253
Query: 387 DHEDHDDS 394
D D DS
Sbjct: 1254 DSSDSSDS 1261
Score = 45.4 bits (106), Expect = 2e-04
Identities = 48/210 (22%), Positives = 81/210 (38%), Gaps = 18/210 (8%)
Query: 208 NSQQDEDESSIESDEFDMSDSTRMSAVNSDLSSNLEERMQSPQNLHGQQDDDSAAESFNG 267
++ D +SS SD D S R + NS SS+ + S + ++S+ S +
Sbjct: 836 SNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSS 895
Query: 268 NETLGHSSIASGGTHSREMGDS-NSDGKTGLEQDEQPLNLSDSPLSAQLTSEYRIDDHNS 326
+ + S +S ++S + DS NS + N SDS S+ +S+ ++S
Sbjct: 896 DSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSD-SSDSSDSSNSS 954
Query: 327 NGKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVDRGAEDLSLNRGDEDE- 385
+ N + SD + N S S S SS S ++S D S N D +
Sbjct: 955 DSSNSSDSSNSSD-----SSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDS 1009
Query: 386 ----------DDHEDHDDSEKVNETDGVEA 405
D D S + +D ++
Sbjct: 1010 SDSSDSSNSSDSSNSSDSSNSSDSSDSSDS 1039
Score = 45.4 bits (106), Expect = 2e-04
Identities = 47/193 (24%), Positives = 77/193 (39%), Gaps = 5/193 (2%)
Query: 208 NSQQDEDESSIESDEFDMSDSTRMS-AVNSDLSSNLEERMQSPQNLHGQQDDDSAAESFN 266
+ D +SS SD D SDS+ S + NS SS+ E S + DS+ S +
Sbjct: 1112 SDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDS 1171
Query: 267 GNETLGHSSIASGGTHSREMGDSNSDGKTGLEQDEQPLNLSDSPLSAQLTSEYRIDDHNS 326
+ + SS +S + S + DS SD + + + S S S D +S
Sbjct: 1172 SDSS--DSSNSSDSSDSSDSSDS-SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1228
Query: 327 NGKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVDRGAEDLSLNRGDEDED 386
+ N+ + S + + S S S S+ DS +ES + N G + +
Sbjct: 1229 SDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDS-NDESDSQSKSGNGNNNGSDSDS 1287
Query: 387 DHEDHDDSEKVNE 399
D E D + ++
Sbjct: 1288 DSEGSDSNHSTSD 1300
Score = 44.7 bits (104), Expect = 3e-04
Identities = 45/198 (22%), Positives = 75/198 (37%), Gaps = 4/198 (2%)
Query: 208 NSQQDEDESSIESDEFDMSDSTRMSAVNSDLSSNLEERMQSPQNLHGQQDDDSAAESFNG 267
+ + +SS SD D + S + NS SS+ + S + DS+ S +
Sbjct: 954 SDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1013
Query: 268 NETLGHSSIASGGTHSREMGDSNSDGKTGLEQDEQPLNLSDSPLSAQLTSEYRIDDHNSN 327
+ + +SS +S + S DS SD + + + S S S D +S+
Sbjct: 1014 DSS--NSSDSSNSSDSSNSSDS-SDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS 1070
Query: 328 GKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVDRGAEDLSLNRGDEDEDD 387
+ + S + N S S S SS S ++S D S N D D
Sbjct: 1071 DSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSD-SSDS 1129
Query: 388 HEDHDDSEKVNETDGVEA 405
+ D S+ N +D ++
Sbjct: 1130 SDSSDSSDSSNSSDSSDS 1147
Score = 44.3 bits (103), Expect = 3e-04
Identities = 46/193 (23%), Positives = 75/193 (38%), Gaps = 4/193 (2%)
Query: 208 NSQQDEDESSIESDEFDMSDSTRMSAVNSDLSSNLEERMQSPQNLHGQQDDDSAAESFNG 267
+ D SS SD D SDS+ S+ +SD S + E S + D S + +
Sbjct: 1049 SDSSDSSNSSDSSDSSDSSDSSD-SSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSD 1107
Query: 268 NETLGHSSIASGGTHSREMGDSNSDGKTGLEQDEQPLNLSDSPLSAQLTSEYRIDDHNSN 327
+ SS +S ++S + DS SD + + S S S D +S+
Sbjct: 1108 SSDSSDSSDSSDSSNSSDSSDS-SDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSS 1166
Query: 328 GKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVDRGAEDLSLNRGDEDEDD 387
+ + S + + S S S SS S ++S D + D S + D D
Sbjct: 1167 DSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD--SSDSSDSSDSSDSSD 1224
Query: 388 HEDHDDSEKVNET 400
D DS + +++
Sbjct: 1225 SSDSSDSNESSDS 1237
Score = 43.9 bits (102), Expect = 5e-04
Identities = 38/194 (19%), Positives = 78/194 (40%), Gaps = 4/194 (2%)
Query: 208 NSQQDEDESSIESDEFDMSDSTRMSAVNSDLSSNLEERMQSPQNLHGQQDDDSAAESFNG 267
+ D +SS SD D SDS+ S NS SS+ + S + + DS+ S +
Sbjct: 1097 SDSSDSSDSSDSSDSSDSSDSSDSS--NSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSS 1154
Query: 268 NETLGHSSIASGGTHSREMGDSNSDGKTGLEQDEQPLNLSDSPLSAQLTSEYRIDDHNSN 327
+ + SS +S + S + DS+ + D + S + +S+ +S+
Sbjct: 1155 DSS--DSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1212
Query: 328 GKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVDRGAEDLSLNRGDEDEDD 387
+ + SD ++ E+ S + S + + S + D + + DE +
Sbjct: 1213 SSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQ 1272
Query: 388 HEDHDDSEKVNETD 401
+ + + +++D
Sbjct: 1273 SKSGNGNNNGSDSD 1286
Score = 43.1 bits (100), Expect = 8e-04
Identities = 43/194 (22%), Positives = 79/194 (40%), Gaps = 4/194 (2%)
Query: 208 NSQQDEDESSIESDEFDMSDSTRMSAVNSDLSSNLEERMQSPQNLHGQQDDDSAAESFNG 267
+ D SS SD D SDS+ S+ +SD S + + S + D S + + +
Sbjct: 1085 SDSSDSSNSSDSSDSSDSSDSSD-SSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSD 1143
Query: 268 NETLGHSSIASGGTHSREMGDSNSDGKTGLEQDEQPLNLSDSPLSAQLT-SEYRIDDHNS 326
+ SS +S + S + DS+ + D N SDS S+ + S D +S
Sbjct: 1144 SSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSS--NSSDSSDSSDSSDSSDSSDSSDS 1201
Query: 327 NGKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVDRGAEDLSLNRGDEDED 386
+ + + S + + S S + SS S ++S D S + D +
Sbjct: 1202 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDS 1261
Query: 387 DHEDHDDSEKVNET 400
+ +D+S+ +++
Sbjct: 1262 TSDSNDESDSQSKS 1275
Score = 40.4 bits (93), Expect = 0.005
Identities = 45/199 (22%), Positives = 75/199 (37%), Gaps = 7/199 (3%)
Query: 208 NSQQDEDESSIESDEFDMSDSTRMSAVNSDLSSNLEERMQSPQNLHGQQDDDSAAESFNG 267
+ D SS S+ D S+S+ S+ +SD S + + S + D S + +
Sbjct: 1010 SDSSDSSNSSDSSNSSDSSNSSD-SSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD 1068
Query: 268 NETLGHSSIASGGTHSREMGDS-----NSDGKTGLEQDEQPLNLSDSPLSAQLTSEYRID 322
+ SS +S + S + DS +SD + + + S S S D
Sbjct: 1069 SSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSD 1128
Query: 323 DHNSNGKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVD-RGAEDLSLNRG 381
+S+ + N S E + S S S SS S ++S D + D S +
Sbjct: 1129 SSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD 1188
Query: 382 DEDEDDHEDHDDSEKVNET 400
D D D DS +++
Sbjct: 1189 SSDSSDSSDSSDSSDSSDS 1207
Score = 39.7 bits (91), Expect = 0.009
Identities = 45/194 (23%), Positives = 73/194 (37%), Gaps = 14/194 (7%)
Query: 208 NSQQDEDESSIESDEFDMSDSTRMSAVNSDLSSNLEERMQSPQNLHGQQDDDSAAESFNG 267
NS D SS SD D S+S+ S +S SS+ + S + DS+ S +
Sbjct: 1122 NSSDSSD-SSDSSDSSDSSNSSDSS--DSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1178
Query: 268 NETLGHSSIASGGTHSREMGDSNSDGKTGLEQDEQPLNLSDSPLSAQLTSEYRIDDHNSN 327
N + SS +S + S + DS+ + D + SDS S+ + D N +
Sbjct: 1179 NSS--DSSDSSDSSDSSDSSDSSDSSDSSDSSDSS--DSSDSSDSSDSSDSSDSSDSNES 1234
Query: 328 GKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVDRGAEDLSLNRGDEDEDD 387
+ SD ++ + S + S S N+ D ++ + N D D
Sbjct: 1235 SDS-------SDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDS 1287
Query: 388 HEDHDDSEKVNETD 401
+ DS D
Sbjct: 1288 DSEGSDSNHSTSDD 1301
>gi|20270337 Leo1, Paf1/RNA polymerase II complex component, homolog
[Homo sapiens]
Length = 666
Score = 47.0 bits (110), Expect = 5e-05
Identities = 49/209 (23%), Positives = 82/209 (39%), Gaps = 25/209 (11%)
Query: 206 LLNSQQDEDESSIESDEFDMSDSTRMSAVNSDLSSNLEERMQSPQNLHGQQDDDSAAESF 265
L S D + +SD SDS + +A + +S E S Q+ G S E F
Sbjct: 7 LFGSDADSEAERKDSDSGSDSDSDQENAASGSNASGSE----SDQDERGDSGQPSNKELF 62
Query: 266 NGNETLGHSSIASGGTHSREMGDSNSDGKTGLEQDEQPLNLSDSPLSAQLTSEYRIDDHN 325
+ +S SG + E D+ S+ + ++ + D ++ ++ + H
Sbjct: 63 GDDSEDEGASHHSGSDNHSERSDNRSEASERSDHEDNDPSDVDQHSGSEAPNDDEDEGHR 122
Query: 326 SNGKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVDRGAEDLSLNRGDE-- 383
S+G + + E E E AHS G+ + D+ ++ N DE
Sbjct: 123 SDGGSHHS---------EAEGSEK-----AHS-DDEKWGREDKSDQSDDEKIQNSDDEER 167
Query: 384 ----DEDDHEDHDDSEKVNETDGVEAERL 408
DED ++ DD EK+ TD E +L
Sbjct: 168 AQGSDEDKLQNSDDDEKMQNTDDEERPQL 196
Score = 36.2 bits (82), Expect = 0.095
Identities = 47/216 (21%), Positives = 85/216 (39%), Gaps = 34/216 (15%)
Query: 209 SQQDEDESSIESDEFDMSDSTRMSAVNSDLSSNLEERMQSPQNLHGQQDDDSAAESFNGN 268
S Q +DE SD+ + + + + + S+ +E+MQ+ + Q D + +
Sbjct: 151 SDQSDDEKIQNSDDEERAQGSDEDKLQN---SDDDEKMQNTDDEERPQLSDDERQQLSEE 207
Query: 269 ETLGHSSIASGGTHSREMGDSNSDGKTGLEQDEQP-------LNLSDSPLSAQLTSEYRI 321
E + R + N D K + +EQP + SD E+R
Sbjct: 208 E-------KANSDDERPVASDNDDEKQNSDDEEQPQLSDEEKMQNSDDERPQASDEEHRH 260
Query: 322 DDHNSNGKNKYKNLLISDLKME--REARENGSKSPAHSYSSYDSGKNES----VDRGAED 375
D +K ++ SD + E R R+N S + + S + K+ S + GA+D
Sbjct: 261 SDDEEEQDHKSESARGSDSEDEVLRMKRKNAIASDSEADSDTEVPKDNSGTMDLFGGADD 320
Query: 376 LSLNRGDEDE--------DDH---EDHDDSEKVNET 400
+S ED+ D++ +D + E + ET
Sbjct: 321 ISSGSDGEDKPPTPGQPVDENGLPQDQQEEEPIPET 356
>gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1
precursor [Homo sapiens]
Length = 513
Score = 43.1 bits (100), Expect = 8e-04
Identities = 44/200 (22%), Positives = 73/200 (36%), Gaps = 36/200 (18%)
Query: 209 SQQDEDESSIESDEFDMSDSTRMSAVNSDLSSNLEERMQSPQNLHGQQDDDSAAESFNGN 268
SQ + SS S E ++S S ++ S P + + +DS + + +
Sbjct: 330 SQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSS 389
Query: 269 ETLGHSSIASGGTHSREMGDSNSDGKTGLEQDEQPLNLSDSPLSAQLTSEYRIDDHNSNG 328
TL HS S E DS S ++ +SP +S+ + H+S+
Sbjct: 390 HTLSHSKSES----REEQADSESSESLNFSEES-----PESPEDENSSSQEGLQSHSSSA 440
Query: 329 KNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVDRGAEDLSLNR-------- 380
+++ + E + E+ S S S S DS ES ED L
Sbjct: 441 ESQSE---------ESHSEEDDSDSQDSSRSKEDSNSTESKSSSEEDGQLKNIEIESRKL 491
Query: 381 ----------GDEDEDDHED 390
GD+D++D +D
Sbjct: 492 TVDAYHNKPIGDQDDNDCQD 511
Score = 40.0 bits (92), Expect = 0.007
Identities = 82/426 (19%), Positives = 150/426 (35%), Gaps = 51/426 (11%)
Query: 211 QDEDESSIESDEFDMSDS-----TRMSAVNSDLSSNLEE-------RMQSPQNLHGQQDD 258
+D+DE D F DS R NS L S+ + +PQ QD
Sbjct: 102 KDDDEDDSGDDTFGDDDSGPGPKDRQEGGNSRLGSDEDSDDTIQASEESAPQGQDSAQDT 161
Query: 259 DSAAESFNGNETLGHSSIASGGTHSREMGD----SNSDGKT----GLEQDEQPLNLSDSP 310
S + + + + T E + SDG++ G E D++ + SD P
Sbjct: 162 TSESRELDNEDRVDSKPEGGDSTQESESEEHWVGGGSDGESSHGDGSELDDEGMQ-SDDP 220
Query: 311 LSAQLTSEYRIDDHNSNGKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVD 370
S + SE NS G +E+ EN ++ ++ DSG ++ ++
Sbjct: 221 ES--IRSERGNSRMNSAGMKS------------KESGENSEQA-----NTQDSGGSQLLE 261
Query: 371 RGAEDLSLNRGDEDEDDHEDHDDSEKVNETDGVEAERLKAFNMFVRLFVDENLDRMVPIS 430
+ + +EDD + DD+ + E V+++ + N D
Sbjct: 262 HPSRKIFRKSRISEEDDRSELDDNNTMEE---VKSDSTENSNSRDTGLSQPRRDSKGDSQ 318
Query: 431 KQPKEKIQAIIDSCRRQFPEYQERARKRIRTYLKSCRRMKRSGFEMSRPIPSHLTSAVAE 490
+ KE + +S P + + + S + E P TS V +
Sbjct: 319 EDSKENLSQ-EESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVED 377
Query: 491 SILASACESESRNAAKRMRLERQQDESAPADKQCKPEATQATYSTSAVPGSQDVLYINGN 550
+ + E +S + + E +++ Q E++++ + P S + +
Sbjct: 378 QEDSDSSEEDSSHTLSHSKSESREE-------QADSESSESLNFSEESPESPEDENSSSQ 430
Query: 551 GTYSYHSYRGLGGGLLNLNDASSSGPTDLSMKRQLATSSGSSSSSNSRPQLSPTEINAVR 610
HS + ++ S D S ++ + S+ S SSS QL EI + +
Sbjct: 431 EGLQSHSSSAESQSEESHSEEDDSDSQDSSRSKEDSNSTESKSSSEEDGQLKNIEIESRK 490
Query: 611 QLVAGY 616
V Y
Sbjct: 491 LTVDAY 496
>gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2
precursor [Homo sapiens]
Length = 497
Score = 43.1 bits (100), Expect = 8e-04
Identities = 44/200 (22%), Positives = 73/200 (36%), Gaps = 36/200 (18%)
Query: 209 SQQDEDESSIESDEFDMSDSTRMSAVNSDLSSNLEERMQSPQNLHGQQDDDSAAESFNGN 268
SQ + SS S E ++S S ++ S P + + +DS + + +
Sbjct: 314 SQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSS 373
Query: 269 ETLGHSSIASGGTHSREMGDSNSDGKTGLEQDEQPLNLSDSPLSAQLTSEYRIDDHNSNG 328
TL HS S E DS S ++ +SP +S+ + H+S+
Sbjct: 374 HTLSHSKSES----REEQADSESSESLNFSEES-----PESPEDENSSSQEGLQSHSSSA 424
Query: 329 KNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVDRGAEDLSLNR-------- 380
+++ + E + E+ S S S S DS ES ED L
Sbjct: 425 ESQSE---------ESHSEEDDSDSQDSSRSKEDSNSTESKSSSEEDGQLKNIEIESRKL 475
Query: 381 ----------GDEDEDDHED 390
GD+D++D +D
Sbjct: 476 TVDAYHNKPIGDQDDNDCQD 495
Score = 40.0 bits (92), Expect = 0.007
Identities = 82/426 (19%), Positives = 150/426 (35%), Gaps = 51/426 (11%)
Query: 211 QDEDESSIESDEFDMSDS-----TRMSAVNSDLSSNLEE-------RMQSPQNLHGQQDD 258
+D+DE D F DS R NS L S+ + +PQ QD
Sbjct: 86 KDDDEDDSGDDTFGDDDSGPGPKDRQEGGNSRLGSDEDSDDTIQASEESAPQGQDSAQDT 145
Query: 259 DSAAESFNGNETLGHSSIASGGTHSREMGD----SNSDGKT----GLEQDEQPLNLSDSP 310
S + + + + T E + SDG++ G E D++ + SD P
Sbjct: 146 TSESRELDNEDRVDSKPEGGDSTQESESEEHWVGGGSDGESSHGDGSELDDEGMQ-SDDP 204
Query: 311 LSAQLTSEYRIDDHNSNGKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVD 370
S + SE NS G +E+ EN ++ ++ DSG ++ ++
Sbjct: 205 ES--IRSERGNSRMNSAGMKS------------KESGENSEQA-----NTQDSGGSQLLE 245
Query: 371 RGAEDLSLNRGDEDEDDHEDHDDSEKVNETDGVEAERLKAFNMFVRLFVDENLDRMVPIS 430
+ + +EDD + DD+ + E V+++ + N D
Sbjct: 246 HPSRKIFRKSRISEEDDRSELDDNNTMEE---VKSDSTENSNSRDTGLSQPRRDSKGDSQ 302
Query: 431 KQPKEKIQAIIDSCRRQFPEYQERARKRIRTYLKSCRRMKRSGFEMSRPIPSHLTSAVAE 490
+ KE + +S P + + + S + E P TS V +
Sbjct: 303 EDSKENLSQ-EESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVED 361
Query: 491 SILASACESESRNAAKRMRLERQQDESAPADKQCKPEATQATYSTSAVPGSQDVLYINGN 550
+ + E +S + + E +++ Q E++++ + P S + +
Sbjct: 362 QEDSDSSEEDSSHTLSHSKSESREE-------QADSESSESLNFSEESPESPEDENSSSQ 414
Query: 551 GTYSYHSYRGLGGGLLNLNDASSSGPTDLSMKRQLATSSGSSSSSNSRPQLSPTEINAVR 610
HS + ++ S D S ++ + S+ S SSS QL EI + +
Sbjct: 415 EGLQSHSSSAESQSEESHSEEDDSDSQDSSRSKEDSNSTESKSSSEEDGQLKNIEIESRK 474
Query: 611 QLVAGY 616
V Y
Sbjct: 475 LTVDAY 480
>gi|122937247 unc-13 homolog A [Homo sapiens]
Length = 1791
Score = 42.7 bits (99), Expect = 0.001
Identities = 63/264 (23%), Positives = 106/264 (40%), Gaps = 51/264 (19%)
Query: 179 KPPTLVTSMID--YNMPITM----AYMKHMKLQLLNSQQDEDESSIESDEFDMSDSTRMS 232
K PT ++D + +P+ + A KL+ LN+ +D+DE S + ++
Sbjct: 202 KDPTFHRILLDTRFELPLDIPEEEARYWAKKLEQLNAMRDQDEYSFQDEQDKPLPVPSNQ 261
Query: 233 AVNSDLSSNLEERMQSPQNLHGQQDDDSAAESFNG-----------NETLGHSSIASGGT 281
N + E+ P + +D D +E+ N N ++ S+
Sbjct: 262 CCNWNYFGWGEQHNDDPDSAVDDRDSDYRSETSNSIPPPYYTTSQPNASVHQYSVRPPPL 321
Query: 282 HSREMGDSNSDGKTGLEQDEQPLNLSD------------SPLSAQLTSEYRIDDHNSNGK 329
SRE S SD E+ +P LS S S+QL+ ++ D+H+ G
Sbjct: 322 GSRE---SYSDSMHSYEEFSEPQALSPTGSSRYASSGELSQGSSQLSEDFDPDEHSLQG- 377
Query: 330 NKYKNLLISDLKMEREARENGSKSPAHSYSSY--DSGK----NESVDRGAEDLSLNRGDE 383
SD++ E R+ S HS SY DS + E ++ ED L +
Sbjct: 378 --------SDMEDE---RDRDSYHSCHSSVSYHKDSPRWDQDEEELEEDLEDF-LEEEEL 425
Query: 384 DEDDHEDHDDSEKVNETDGVEAER 407
ED+ E ++ E+V + G A+R
Sbjct: 426 PEDEEELEEEEEEVPDDLGSYAQR 449
>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
Length = 2968
Score = 42.0 bits (97), Expect = 0.002
Identities = 40/166 (24%), Positives = 67/166 (40%), Gaps = 17/166 (10%)
Query: 244 ERMQSPQNLHGQQDDDSAAESFNGNETLGHSSIASGG-THSREMGDSNSDG--KTGLEQD 300
++ Q+ Q+ G ++ +S++ S +G+ + SS +SG T E GD N DG TG
Sbjct: 2545 DKAQAEQD--GAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNC 2602
Query: 301 EQPLNLSDSPLSAQLTSEYRIDDHNSNGKNKYKNLLISDLKMEREARENGSKSPAHSYSS 360
+ + SP S+ +S +S+ + + + S S + S SS
Sbjct: 2603 SAASSRAASPASSSSSSSSSSSSSSSSSSS------------SSSSSSSSSSSSSSSSSS 2650
Query: 361 YDSGKNESVDRGAEDLSLNRGDEDEDDHEDHDDSEKVNETDGVEAE 406
S + S + S + DED DD T G A+
Sbjct: 2651 SSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQ 2696
>gi|115529449 upstream binding transcription factor, RNA polymerase
I isoform b [Homo sapiens]
Length = 727
Score = 40.0 bits (92), Expect = 0.007
Identities = 33/102 (32%), Positives = 41/102 (40%), Gaps = 18/102 (17%)
Query: 305 NLSDSPLSAQLTSEYRIDDHNSNGKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSG 364
N S + Q SE DD D E E ENG S SS S
Sbjct: 626 NPKSSRTTLQSKSESEEDDEEDEDDE--------DEDEEEEDDENGDSSEDGGDSSESSS 677
Query: 365 KNESVDRGAEDLSLNRGDEDEDDHEDHDDSEKVNETDGVEAE 406
++ES D GDE+E+D ED DD E +E + E+E
Sbjct: 678 EDESED----------GDENEEDDEDEDDDEDDDEDEDNESE 709
>gi|115529451 upstream binding transcription factor, RNA polymerase
I isoform b [Homo sapiens]
Length = 727
Score = 40.0 bits (92), Expect = 0.007
Identities = 33/102 (32%), Positives = 41/102 (40%), Gaps = 18/102 (17%)
Query: 305 NLSDSPLSAQLTSEYRIDDHNSNGKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSG 364
N S + Q SE DD D E E ENG S SS S
Sbjct: 626 NPKSSRTTLQSKSESEEDDEEDEDDE--------DEDEEEEDDENGDSSEDGGDSSESSS 677
Query: 365 KNESVDRGAEDLSLNRGDEDEDDHEDHDDSEKVNETDGVEAE 406
++ES D GDE+E+D ED DD E +E + E+E
Sbjct: 678 EDESED----------GDENEEDDEDEDDDEDDDEDEDNESE 709
>gi|7657671 upstream binding transcription factor, RNA polymerase I
isoform a [Homo sapiens]
Length = 764
Score = 40.0 bits (92), Expect = 0.007
Identities = 33/102 (32%), Positives = 41/102 (40%), Gaps = 18/102 (17%)
Query: 305 NLSDSPLSAQLTSEYRIDDHNSNGKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSG 364
N S + Q SE DD D E E ENG S SS S
Sbjct: 663 NPKSSRTTLQSKSESEEDDEEDEDDE--------DEDEEEEDDENGDSSEDGGDSSESSS 714
Query: 365 KNESVDRGAEDLSLNRGDEDEDDHEDHDDSEKVNETDGVEAE 406
++ES D GDE+E+D ED DD E +E + E+E
Sbjct: 715 EDESED----------GDENEEDDEDEDDDEDDDEDEDNESE 746
>gi|148612801 KIAA1009 protein [Homo sapiens]
Length = 1403
Score = 40.0 bits (92), Expect = 0.007
Identities = 39/167 (23%), Positives = 74/167 (44%), Gaps = 16/167 (9%)
Query: 191 NMPITMAYMKHMKLQLLNSQQDEDESSIESDEFDMSDS---TRMSAVNSDLSSNLEERMQ 247
N+ + +KH +L + D+D+ +S EF + + ++ +N +L++ E
Sbjct: 1044 NLEAEIDVLKHQNAELDVKKNDKDDEDFQSIEFQVEQAHAKAKLVRLNEELAAKKREIQD 1103
Query: 248 SPQNLHGQQDDDS---AAESFNGNETLGHSSIASGGTHSREMGDSNSDGKTGLEQDEQPL 304
+ + Q D + ++ G E + HS + G++NS T + QP
Sbjct: 1104 LSKTVERLQKDRRMMLSNQNSKGREEMSAKRAKKDVLHSSK-GNANSFPGTLDSKLYQPH 1162
Query: 305 NLSDSPLSAQLTSEYRIDDHNSNGKNKYKNLLI--SDLKMEREAREN 349
+DS +S L YR+ KN+ + L+ ++LKM+ EA N
Sbjct: 1163 TFTDSHVSEVLQENYRL-------KNELEGLISEKNELKMKSEAVMN 1202
>gi|57864582 hornerin [Homo sapiens]
Length = 2850
Score = 39.3 bits (90), Expect = 0.011
Identities = 40/165 (24%), Positives = 58/165 (35%), Gaps = 7/165 (4%)
Query: 209 SQQDEDESSIESDEFDMS-DSTRMSAVNSDLSSNLEERMQSPQNLHGQQDDDSAAESFNG 267
SQ +S +S FD ST S+ + S S + +GQQ S G
Sbjct: 2249 SQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSG-----SSQSSSYGQQGSGSGQSPSRG 2303
Query: 268 NETLGHSSIASGGTHSREMGDSNSDGKTGLEQDEQPLNLSDSPLSAQLTSEYRIDDHNSN 327
G +S G H G S+S G+ G Q S+ +S Y S
Sbjct: 2304 RHGSGSGHSSSYGQHGSGSGWSSSSGRHG-SGSGQSSGFGHHESSSWQSSGYTQHGSGSG 2362
Query: 328 GKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVDRG 372
+ Y+ + R R S + SY + SG +S+ G
Sbjct: 2363 HSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHG 2407
Score = 37.7 bits (86), Expect = 0.033
Identities = 39/165 (23%), Positives = 58/165 (35%), Gaps = 7/165 (4%)
Query: 209 SQQDEDESSIESDEFDMS-DSTRMSAVNSDLSSNLEERMQSPQNLHGQQDDDSAAESFNG 267
SQ +S +S FD ST S+ + S S + +GQQ S G
Sbjct: 1779 SQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSG-----SSQSSSYGQQGSGSGQSPSRG 1833
Query: 268 NETLGHSSIASGGTHSREMGDSNSDGKTGLEQDEQPLNLSDSPLSAQLTSEYRIDDHNSN 327
G +S G H G S+S G+ G Q S+ +S Y S
Sbjct: 1834 RHGSGSGHSSSYGQHGSGSGWSSSSGRHG-SGSGQSSGFGHHESSSWQSSGYTQHGSGSG 1892
Query: 328 GKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVDRG 372
+ Y+ + R + S + SY + SG +S+ G
Sbjct: 1893 HSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHG 1937
Score = 34.7 bits (78), Expect = 0.28
Identities = 33/150 (22%), Positives = 50/150 (33%), Gaps = 5/150 (3%)
Query: 253 HGQQDDDSAAESFNGNETLGHSSIASGGTHSREMGDSNSDGKTGLEQDEQPLNLSDSPLS 312
+G+Q+ DS S G G + G H G S+S+ G Q S S
Sbjct: 179 YGEQNSDSHQSSGRGQCGSGSGQSPNYGQHGSGSGQSSSNDTHG-SGSGQSSGFSQHKSS 237
Query: 313 AQLTSEYRIDDHNSNGKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVDRG 372
+ +S Y S + Y + R R S + SY + SG +S+ G
Sbjct: 238 SGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHG 297
Query: 373 AEDLSLNRGDEDEDDHEDHDDSEKVNETDG 402
+ G H H + + G
Sbjct: 298 RQ----GSGSRQSPSHVRHGSGSGHSSSHG 323
Score = 34.7 bits (78), Expect = 0.28
Identities = 31/136 (22%), Positives = 51/136 (37%), Gaps = 17/136 (12%)
Query: 253 HGQQDDDSAAESFNGNETLGHSSIASGGTHSREMGDSNSDGKTGLEQDEQPLNLSDSPLS 312
HGQ S+ S G + G S G H + G S+S G+ G N +S
Sbjct: 636 HGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVS 695
Query: 313 AQLT--------------SEYRIDDHNSNGKNKYKNLLISDLKMEREARENGSKSPAHSY 358
Q + S++ +S+G K+ + + E+ +G S SY
Sbjct: 696 GQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSS---SY 752
Query: 359 SSYDSGKNESVDRGAE 374
+ SG ++S G +
Sbjct: 753 GQHGSGSHQSSGHGRQ 768
Score = 30.8 bits (68), Expect = 4.0
Identities = 36/165 (21%), Positives = 54/165 (32%), Gaps = 19/165 (11%)
Query: 208 NSQQDEDESSIESDEFDMSDSTRMSAVNSDLSSNLEERMQSPQNLHGQQDDDSAAESFNG 267
+S D SS +S + +S A S + QSP HGQ+ S G
Sbjct: 852 SSSGQHDSSSGQSSSYGQHESASHHA--SGRGRHGSGSGQSPG--HGQRGSGSGQSPSYG 907
Query: 268 NETLGHSSIASGGTHSREMGDSNSDGKTGLEQDEQPLNLSDSPLSAQLTSEYRIDDHNSN 327
G +S G H G S+ G S+ +S Y S
Sbjct: 908 RHGSGSGRSSSSGRHGSGSGQSSGFGHKS---------------SSGQSSGYTQHGSGSG 952
Query: 328 GKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVDRG 372
+ Y+ + R + S + SY + SG +S+ G
Sbjct: 953 HSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHG 997
Score = 30.0 bits (66), Expect = 6.8
Identities = 28/124 (22%), Positives = 49/124 (39%), Gaps = 5/124 (4%)
Query: 253 HGQQDDDSAAESFNGNETLGHSSIASGGTHSREMGDSNSDGK--TGLEQDEQPLNLSDSP 310
+G+Q S +G G S G H G S+S G+ +GL + + S
Sbjct: 1115 YGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSS 1174
Query: 311 LSAQLTSEYRIDDHNSNGKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVD 370
+ S++ +S+G ++ + + ER +GS S Y + SG +S
Sbjct: 1175 GQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSS---HYGQHGSGSRQSSG 1231
Query: 371 RGAE 374
G +
Sbjct: 1232 HGRQ 1235
Score = 30.0 bits (66), Expect = 6.8
Identities = 28/124 (22%), Positives = 49/124 (39%), Gaps = 5/124 (4%)
Query: 253 HGQQDDDSAAESFNGNETLGHSSIASGGTHSREMGDSNSDGK--TGLEQDEQPLNLSDSP 310
+G+Q S +G G S G H G S+S G+ +GL + + S
Sbjct: 2525 YGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSS 2584
Query: 311 LSAQLTSEYRIDDHNSNGKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVD 370
+ S++ +S+G ++ + + ER +GS S Y + SG +S
Sbjct: 2585 GQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSS---HYGQHGSGSRQSSG 2641
Query: 371 RGAE 374
G +
Sbjct: 2642 HGRQ 2645
>gi|55741677 SET domain containing 1A [Homo sapiens]
Length = 1707
Score = 39.3 bits (90), Expect = 0.011
Identities = 26/99 (26%), Positives = 43/99 (43%), Gaps = 5/99 (5%)
Query: 209 SQQDEDESSIESDEFDMSDSTRMSAVN-----SDLSSNLEERMQSPQNLHGQQDDDSAAE 263
SQ+ E E DE D D R AV+ +++S +E S D D +
Sbjct: 969 SQESSSEKDEEDDEEDEEDEDREEAVDTTKKETEVSDGEDEESDSSSKCSLYADSDGEND 1028
Query: 264 SFNGNETLGHSSIASGGTHSREMGDSNSDGKTGLEQDEQ 302
S + +E+ SS +S + S S+S ++ E +E+
Sbjct: 1029 STSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEE 1067
Score = 31.2 bits (69), Expect = 3.1
Identities = 24/106 (22%), Positives = 45/106 (42%), Gaps = 1/106 (0%)
Query: 496 ACESESRNAAKRMRLER-QQDESAPADKQCKPEATQATYSTSAVPGSQDVLYINGNGTYS 554
A +SE A++ E+ ++D+ + + + EA T + V +D + +
Sbjct: 960 ALDSEGEEASQESSSEKDEEDDEEDEEDEDREEAVDTTKKETEVSDGEDEESDSSSKCSL 1019
Query: 555 YHSYRGLGGGLLNLNDASSSGPTDLSMKRQLATSSGSSSSSNSRPQ 600
Y G + +SSS + S ++SS SSS S+S +
Sbjct: 1020 YADSDGENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDE 1065
>gi|197245440 hypothetical protein LOC23285 [Homo sapiens]
Length = 1354
Score = 39.3 bits (90), Expect = 0.011
Identities = 44/171 (25%), Positives = 69/171 (40%), Gaps = 26/171 (15%)
Query: 207 LNSQQDEDESSIE----------SDEFDMSDSTRMSAVNSDLSSNLEERMQSPQNLHGQQ 256
LNS Q++ +S + SDE M D + + +SD+SS S +N
Sbjct: 719 LNSAQEDKKSKVPVEGLTIPSKLSDESAM-DEDKHATADSDVSSKCFSGQLSEKNSPKNM 777
Query: 257 DDDSAAESFNGNET--LGHSSIASGGTHSREMGDSNSDGKTGLEQDEQPLNLSDSPLSAQ 314
+ + ES ET +GH ++++G H RE +S++ T D +P + +Q
Sbjct: 778 ETSESPESHETPETPFVGHWNLSTGVLHQRESPESDTGSATTSSDDIKPRSEDYDAGGSQ 837
Query: 315 LTSEYRIDDHNSN--GKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDS 363
DD SN G +K +L D R + S YDS
Sbjct: 838 -------DDDGSNDRGISKCGTMLCHDFL----GRSSSDTSTPEELKIYDS 877
>gi|19526767 MLK-related kinase isoform 2 [Homo sapiens]
Length = 455
Score = 38.9 bits (89), Expect = 0.015
Identities = 20/69 (28%), Positives = 39/69 (56%), Gaps = 5/69 (7%)
Query: 330 NKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVDRGAEDLSLNRGDEDEDDHE 389
NK ++ S +++ +A++N SK+ +S GK ++ G D L+ GD+D+DD
Sbjct: 390 NKAGAVMHSGMQINMQAKQNSSKT-----TSKRRGKKVNMALGFSDFDLSEGDDDDDDDG 444
Query: 390 DHDDSEKVN 398
+ +D++ N
Sbjct: 445 EEEDNDMDN 453
>gi|16445033 ACRC protein [Homo sapiens]
Length = 691
Score = 38.5 bits (88), Expect = 0.019
Identities = 43/201 (21%), Positives = 78/201 (38%), Gaps = 11/201 (5%)
Query: 208 NSQQDEDESSIESDEFDMSDSTRMSAVNSDLSSNLEERMQSPQNLHGQQD--DDSAAESF 265
+S + D+S + D+ D SD S+ +SD+ + + ++P + + DDS+ +S
Sbjct: 204 SSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSE 263
Query: 266 NGNETLGHSSIASGGTHSREMGDSNSDGKTGLEQDEQPLNLSDSPLSAQLTSEYRIDDH- 324
+++ S + E D +SD + D E + DD
Sbjct: 264 APDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPEDKSDDSD 323
Query: 325 --NSNGKNKYKNLLISDLKMERE--ARENGSKSPAHSYSSYDSGKNESVDRGAEDLSLNR 380
+ N + + DL E + + E A + S +DS S D G +DL N
Sbjct: 324 VPDDNSDDLEVPVPAEDLCNEGQIASDEEELVEAAAAVSQHDS----SDDAGEQDLGENL 379
Query: 381 GDEDEDDHEDHDDSEKVNETD 401
D + + SE+ T+
Sbjct: 380 SKPPSDPEANPEVSERKLPTE 400
Score = 30.4 bits (67), Expect = 5.2
Identities = 42/212 (19%), Positives = 72/212 (33%), Gaps = 20/212 (9%)
Query: 208 NSQQDEDESSIESDEFDMSDSTRMSAVNSDLSSNLEERMQSPQNLHGQQ-DDDSAAESFN 266
+S+ +D S D SD + + NSD SS+ S N DD + +S
Sbjct: 165 DSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDV 224
Query: 267 GNETLGHSSIASGGTHSREMGDSNSDGKTGLEQDEQPLNLSDSPLSAQLTSEYRIDDHNS 326
+++ S + + E D +SD + D + DD +
Sbjct: 225 PDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEA 284
Query: 327 NGKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVDRGAEDLSL-------- 378
+ + + D + EA ++ KS S ++ D ++DL +
Sbjct: 285 SDDSSDDSEASDDSSDDSEAPDD--KSDDSDVPEDKSDDSDVPDDNSDDLEVPVPAEDLC 342
Query: 379 NRGDEDEDDHE---------DHDDSEKVNETD 401
N G D+ E HD S+ E D
Sbjct: 343 NEGQIASDEEELVEAAAAVSQHDSSDDAGEQD 374
>gi|151301053 RNA binding motif protein 33 [Homo sapiens]
Length = 1170
Score = 38.1 bits (87), Expect = 0.025
Identities = 59/285 (20%), Positives = 105/285 (36%), Gaps = 37/285 (12%)
Query: 221 DEFDMSD------STRMSAVNSDLSSNLEERMQSPQNLHGQ----------------QDD 258
D+FD D S R A + D S LE+ + L G+ Q D
Sbjct: 16 DDFDQFDKPGAERSWRRRAADEDWDSELEDDLLGEDLLSGKKNQSDLSDEELNDDLLQSD 75
Query: 259 DSAAESFNGNETLGHSSIASGGTHSREMGDSNSDGKTGLEQDEQPLNLSDSPLSAQLTSE 318
+ E+F+ + SG S E+ D+ +D ++G ++ E + L +
Sbjct: 76 NEDEENFSSQGVTISLNATSGMVTSFELSDNTND-QSGEQESEYEQEQGEDELVYHKSDG 134
Query: 319 YRIDDHNSNGKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVDR---GAED 375
+ + +Y+ + + E E + ++ D NE +D G E
Sbjct: 135 SELYTQEYPEEGQYEGHEAELTEDQIEYVEEPEEEQLYTDEVLDIEINEPLDEFTGGMET 194
Query: 376 LSLNRGDEDEDDHEDHDDSEKVNETDGVEAERLKAFNMFVRLFVDENLDRMVPISKQPKE 435
L L + ++E D E+ DD E E + +RL R +P + +
Sbjct: 195 LELQKDIKEESDEEEEDDEESGRLRFKTERKE----GTIIRLSDVTRERRNIPETLELSA 250
Query: 436 KIQAIIDSCRRQFPEYQERARKRIRTYLKSCRRMKRSGFEMSRPI 480
+ +A + E++ER R+ + S R +R G M R +
Sbjct: 251 EAKAAL-------LEFEERERQHKQGRYSSRRGGRRGGPLMCRGV 288
>gi|46195755 SCAN domain containing 3 [Homo sapiens]
Length = 1325
Score = 38.1 bits (87), Expect = 0.025
Identities = 17/59 (28%), Positives = 29/59 (49%), Gaps = 8/59 (13%)
Query: 106 EDFFDIIYSMHVETGPNGEQIRKHAGQKRTYKAISESYAFLPREAVTRFLMSCSECQKR 164
ED FDI+++ H+ G H G+ R K + Y + +E + +L C CQ++
Sbjct: 305 EDLFDILHNTHLSIG--------HGGRTRMEKELQAKYKNITKEVIMLYLTLCKPCQQK 355
>gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo
sapiens]
Length = 2168
Score = 38.1 bits (87), Expect = 0.025
Identities = 41/164 (25%), Positives = 64/164 (39%), Gaps = 25/164 (15%)
Query: 233 AVNSDLSSNLEERMQSPQNLHGQQDDDSAAESFNGNET---LGHSSIASGGTHSREMGDS 289
A N D SS+ R N +G + + S NG+ T +G ++ T S MG +
Sbjct: 144 AQNHD-SSSFHSRTSGKSNRNGPEKGVNG--SINGSNTSSVIGINTSVLSTTASSSMGQT 200
Query: 290 NSDGKTGLEQDEQPLNLSDSPLSAQLTSEYRIDDHNSNGKNKYKNLLISDLKMEREAREN 349
S G + + PL A R+D I D K ++A E+
Sbjct: 201 KSTSSGGGNRKCNQEQSKNQPLDA------RVDK-------------IKDKKPRKKAMES 241
Query: 350 GSKSPAHSYSSYDSGKNESVDRGAEDLSLNRGDEDEDDHEDHDD 393
S S + S +S D+ ++DL + +ED+ E DD
Sbjct: 242 SSNSDSDSGTSSDTSSEGISSSDSDDLEEDEEEEDQSIEESEDD 285
Score = 35.0 bits (79), Expect = 0.21
Identities = 34/142 (23%), Positives = 56/142 (39%), Gaps = 13/142 (9%)
Query: 278 SGGTHSREMGDSNSDG-KTGLE------QDEQPLNLSDSPLSAQLTSEYRIDDHNSNGKN 330
S HSR G SN +G + G+ + ++ S LS +S S+G
Sbjct: 149 SSSFHSRTSGKSNRNGPEKGVNGSINGSNTSSVIGINTSVLSTTASSSMGQTKSTSSGGG 208
Query: 331 KYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVDRG------AEDLSLNRGDED 384
K +AR + K + +S N D G +E +S + D+
Sbjct: 209 NRKCNQEQSKNQPLDARVDKIKDKKPRKKAMESSSNSDSDSGTSSDTSSEGISSSDSDDL 268
Query: 385 EDDHEDHDDSEKVNETDGVEAE 406
E+D E+ D S + +E D ++E
Sbjct: 269 EEDEEEEDQSIEESEDDDSDSE 290
Score = 33.1 bits (74), Expect = 0.80
Identities = 25/106 (23%), Positives = 47/106 (44%), Gaps = 15/106 (14%)
Query: 213 EDESSIESDEFDMSDSTRMSAVNSDLSSNLEERMQSPQNLHGQQDDDSAAES----FNGN 268
E S+ +SD SD++ +SD E+ + Q++ +DDDS +ES + N
Sbjct: 240 ESSSNSDSDSGTSSDTSSEGISSSDSDDLEEDEEEEDQSIEESEDDDSDSESEAQHKSNN 299
Query: 269 ETLGHSSIASGGTHSREMGDSNSDGKTGLEQDEQPLNLSDSPLSAQ 314
+ L H + D +DG+ E+ ++ PL+++
Sbjct: 300 QVLLHG-----------ISDPKADGQKATEKAQEKRIHQPLPLASE 334
Score = 31.6 bits (70), Expect = 2.3
Identities = 22/82 (26%), Positives = 43/82 (52%), Gaps = 7/82 (8%)
Query: 325 NSNGKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVDRGAEDLSLNRGDED 384
+S GK K + ++ +K + + +KS + DS S D +ED + DE+
Sbjct: 560 HSQGKEKAVSNNVNPVKTQHHSHP--AKSLVEQFRGTDSDIPSSKD--SED---SNEDEE 612
Query: 385 EDDHEDHDDSEKVNETDGVEAE 406
EDD E+ ++ ++ +E+D ++E
Sbjct: 613 EDDEEEDEEDDEDDESDDSQSE 634
Score = 30.8 bits (68), Expect = 4.0
Identities = 17/43 (39%), Positives = 26/43 (60%), Gaps = 1/43 (2%)
Query: 364 GKNESVDRGAEDLSLNRGDEDEDDHEDHDDSEKVNETDGVEAE 406
G + D +D S ++GDED++D ED +D +K +TD E E
Sbjct: 1294 GGDSDYDDDDDDDSDDQGDEDDEDEEDKED-KKGKKTDICEDE 1335
Score = 30.0 bits (66), Expect = 6.8
Identities = 44/196 (22%), Positives = 79/196 (40%), Gaps = 29/196 (14%)
Query: 215 ESSIESDEFDMSDSTRM-SAVNSDLSSNLEERMQSPQNLHGQQDDDSAAESFNGNETLGH 273
+S I+ ++ T+M S +N ++++ SP NL ++ GN+T
Sbjct: 499 QSVIQEAPLALTTKTKMQSKINENIAAASSTPFSSPVNL------STSGRRTPGNQTPVM 552
Query: 274 SSIASGGTHS--REMGDSNSDGKTGLEQDEQPLNL-------SDSPLSAQLTSEYRIDDH 324
S AS HS +E SN+ + P +DS + + SE +D
Sbjct: 553 PS-ASPILHSQGKEKAVSNNVNPVKTQHHSHPAKSLVEQFRGTDSDIPSSKDSEDSNEDE 611
Query: 325 NSNGKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVDRGAEDLSLNRGDED 384
+ + + D + + + + S+S + S S D+ +E D +D DE
Sbjct: 612 EEDDEEE-------DEEDDEDDESDDSQSESDSNSESDTEGSEEEDDDDKDQ-----DES 659
Query: 385 EDDHEDHDDSEKVNET 400
+ D E S K+N+T
Sbjct: 660 DSDTEGEKTSMKLNKT 675
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 37.7 bits (86), Expect = 0.033
Identities = 49/239 (20%), Positives = 89/239 (37%), Gaps = 23/239 (9%)
Query: 193 PITMAYMKHMKLQLLNSQQDEDESSIESDEFDMSDSTRMSAVNSDLSSNLEERMQSPQNL 252
P T + +L+ S +EDE S + DM+D+ A + R P L
Sbjct: 970 PDTTSSGDQKRLRPSTSVDEEDEESERERDRDMADTPCELAKRDPKGVGVRRRPARPLEL 1029
Query: 253 HGQQDDDSAAESFNGNETLGHSSIASGGTHSREMGDSNSDGKTGLEQDEQPLNLSDSPLS 312
++D E+ A + D +SD + E D++ LS++
Sbjct: 1030 DSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEA--- 1086
Query: 313 AQLTSEYRIDDHNSNGKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVDRG 372
+ + ++ + + I K E + S+S + SS +S + S D
Sbjct: 1087 ---------SEKDEGDSDEEETVSIVTSKAEATSSSESSES-SEFESSSESSPSSSED-- 1134
Query: 373 AEDLSLNRGDEDEDDHEDHDDSEKVN-------ETDGVEAERLKAFNMFVRLFVDENLD 424
E+ + R +E+E++ E+ E + E DG EA L ++E +D
Sbjct: 1135 -EEEVVAREEEEEEEEEEMVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVD 1192
>gi|56711320 hypothetical protein LOC145407 [Homo sapiens]
Length = 774
Score = 37.7 bits (86), Expect = 0.033
Identities = 77/356 (21%), Positives = 138/356 (38%), Gaps = 46/356 (12%)
Query: 196 MAYMKHMKLQLLNSQQDEDESSIESDE-FDMSDSTRMSAVNSDLSSNLEERMQ---SPQN 251
M MK + LL S D ES+ E+D F + + +S S+ L M+ + +
Sbjct: 404 MEDMKVSIVNLLQSTGDFTESTKENDALFFLETTVSVSVYESEADQLLGNTMKDIITQEM 463
Query: 252 LHGQQDDDSAAESFNGNETLGHSSIASGGTHSREMGD----SNSDGKTGLEQDEQPLNLS 307
Q+ D+ + I G E D S+ G T L + +PL +
Sbjct: 464 TTAVQEPDATLSMVTQEQVATLELIRDSGKTEEEKEDPSPVSDVPGVTQLSRRWEPLATT 523
Query: 308 DS----PLSAQLTSEYRIDDHNSNGKNK-YKNLLISDLKMEREARENGSKSPAHSYSSYD 362
S PLS ++T G N+ + +L S + S SPA
Sbjct: 524 ISTTVVPLSFEVTPTVEEQMDTVTGPNEEFTPVLGSPVTPPGIMVGEPSISPALPALEAS 583
Query: 363 SGK----------NESVDRGAEDLSLNRGDEDEDDHEDHDDSEKVNETDGVEAERLKAFN 412
S + N + G + L G EDED+ ++ D+ E+ E D E E K +
Sbjct: 584 SERRTVVPSITRVNTAASYGLDQLESEEGQEDEDEEDEEDEDEE--EEDEEEDEEDKDAD 641
Query: 413 MFVRLFVDENLDRMVPI---------SKQP--KEKIQAIIDSCRRQFP---EYQERARKR 458
+DE LD + S++P +E +++ Q P E++++ +
Sbjct: 642 S-----LDEGLDGDTELPGFTLPGITSQEPGLEEGNMDLLEGATYQVPDALEWEQQNQGL 696
Query: 459 IRTYLKSCRRMKRSGFEMSRPIPSHLTSAVAESILASACESESRNAAKRMRLERQQ 514
+R++++ + ++G+ +P + A A IL + + N +R +R +
Sbjct: 697 VRSWMEKLK--DKAGYMSGMLVPVGVGIAGALFILGALYSIKVMNRRRRNGFKRHK 750
>gi|4504487 histidine rich calcium binding protein precursor [Homo
sapiens]
Length = 699
Score = 37.4 bits (85), Expect = 0.043
Identities = 44/213 (20%), Positives = 90/213 (42%), Gaps = 26/213 (12%)
Query: 200 KHMKLQLLNSQQDEDESSIESDEFDMSDSTRMSAVNSDLSSNLEERMQSPQNLHG----Q 255
+H+ L++ +++E+E +++ + S R + + + E + + P + H +
Sbjct: 367 QHVHHGLVDEEEEEEEITVQFGHYVASHQPRGHKSDEEDFQD-EYKTEVPHHHHHRVPRE 425
Query: 256 QDDDSAAESFNGNETLGHSSIASGGTHSREMGDSNSDGKTGLEQDEQPLNLSDSPLSAQL 315
+D++ +AE LGH + + +H D +TG Q +S P +
Sbjct: 426 EDEEVSAE-------LGHQAPSHRQSHQ--------DEETGHGQRGSIKEMSHHPPGHTV 470
Query: 316 TSEYRIDDHNSNGKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVDRGAED 375
+ + + + K K + + E+ E G K H + ++E G
Sbjct: 471 VKDRSHLRKDDSEEEKEKEEDPGSHEEDDESSEQGEKGTHHGSRDQEDEEDEEEGHG--- 527
Query: 376 LSLNRGDEDEDD---HEDHDDSEKVNETDGVEA 405
LSLN+ +E+E+D E+ +D E+ E V A
Sbjct: 528 LSLNQEEEEEEDKEEEEEEEDEERREERAEVGA 560
Score = 33.1 bits (74), Expect = 0.80
Identities = 42/205 (20%), Positives = 74/205 (36%), Gaps = 37/205 (18%)
Query: 201 HMKLQLLNSQQDEDESSIESDEFDMSDSTRMSAVNSDLSSNLEERMQSPQNLHGQQDDDS 260
H+ +S QDEDE + S E + R ++ G+++++
Sbjct: 151 HLPSHRSHSHQDEDEDEVVSSE------------HHHHILRHGHRGHDGEDDEGEEEEEE 198
Query: 261 AAESFNGNETLGHSSIASGGTHSREMGDSNSDG----------KTGLEQDEQPLNLSDSP 310
E + GH + G H E + SDG + E D+ + D
Sbjct: 199 EEEEEEASTEYGHQAHRHRG-HGSEEDEDVSDGHHHHGPSHRHQGHEEDDDDDDDDDDDD 257
Query: 311 LSAQLTSEYRIDDHNSNGKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVD 370
++ EYR H G ++ +SD R+ P+H + S++ N+
Sbjct: 258 DDDDVSIEYRHQAHRHQGHGIEEDEDVSDGHHHRD--------PSHRHRSHEEDDNDD-- 307
Query: 371 RGAEDLSLNRGDEDEDDHEDHDDSE 395
+D+S G + H+DH E
Sbjct: 308 ---DDVSTEYGHQ-AHRHQDHRKEE 328
>gi|195976782 Paf1/RNA polymerase II complex component [Homo
sapiens]
Length = 710
Score = 37.4 bits (85), Expect = 0.043
Identities = 57/242 (23%), Positives = 97/242 (40%), Gaps = 35/242 (14%)
Query: 199 MKHMKLQLLNSQQDEDESSIES---DEFDMSDS---TRMSAVNSDLSSNLEERMQS-PQN 251
MK + +S + +SS ES +E ++SDS + S+ +SD SS EE ++
Sbjct: 126 MKKQANKTASSGSSDKDSSAESSAPEEGEVSDSDSNSSSSSSDSDSSSEDEEFHDGYGED 185
Query: 252 LHGQQDDDSAAESFNGNETLGHSSIASGGTHSREMGDSNSDGKTGL------EQDEQPLN 305
L G ++D + E E RE+ + K L E+ E+
Sbjct: 186 LMGDEEDRARLEQMTEKE---REQELFNRIEKREVLKRRFEIKKKLKTAKKKEKKEKKKK 242
Query: 306 LSDSPLSAQLTS--EYRIDDHNSNGKNKY------KNLLISDLKMEREAREN------GS 351
+ +LT E ++ HN ++K K+ + +LK ERE R+N
Sbjct: 243 QEEEQEKKKLTQIQESQVTSHNKERRSKRDEKLDKKSQAMEELKAEREKRKNRTAELLAK 302
Query: 352 KSPAHSYSSYDSGKNESVDRGAEDLS-----LNRGDEDEDDHEDHDDSEKVNETDGVEAE 406
K P + Y + E D + + S + DE+E+ E S+ V+ + +
Sbjct: 303 KQPLKTSEVYSDDEEEEEDDKSSEKSDRSSRTSSSDEEEEKEEIPPKSQPVSLPEELNRV 362
Query: 407 RL 408
RL
Sbjct: 363 RL 364
>gi|24308089 chromodomain helicase DNA binding protein 5 [Homo
sapiens]
Length = 1954
Score = 37.4 bits (85), Expect = 0.043
Identities = 32/130 (24%), Positives = 54/130 (41%), Gaps = 19/130 (14%)
Query: 320 RIDDHNSNGKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVDRGAEDLSLN 379
++ ++ GK K K +L E E S+S YS K + D+ +
Sbjct: 55 KLKENKCKGKRKKKEGSNDELSENEEDLEEKSESEGSDYSPNKKKKKKLKDKKEKKAKRK 114
Query: 380 RGDEDEDDHEDH-----------------DDSEKV-NETDGVEAERLKAFNMFVRLFVDE 421
+ DEDEDD++D DD + + +E D KAF+ F+R + +
Sbjct: 115 KKDEDEDDNDDGCLKEPKSSGQLMAEWGLDDVDYLFSEEDYHTLTNYKAFSQFLRPLIAK 174
Query: 422 NLDRMVPISK 431
+ +P+SK
Sbjct: 175 K-NPKIPMSK 183
>gi|68299795 chromodomain helicase DNA binding protein 1 [Homo
sapiens]
Length = 1710
Score = 37.0 bits (84), Expect = 0.056
Identities = 42/173 (24%), Positives = 78/173 (45%), Gaps = 11/173 (6%)
Query: 243 EERMQSPQNLHGQQDDDSAAESFNGNETLGHSSIASGGTHSREMGDSNSDGKTGLEQDEQ 302
EE +++ Q DDDS + S +G+ G SS +S S + G S+SD +G E Q
Sbjct: 7 EESVRNSSGESSQSDDDSGSASGSGS---GSSSGSSSDGSSSQSGSSDSD--SGSESGSQ 61
Query: 303 PLNLSDSPLSAQLTSEYRIDDHNSNGKNKYKNLLISD----LKMEREARENGSKSPAHSY 358
+ SD+ ++ ++ D K+ L + K +++ ++ ++ ++S
Sbjct: 62 SESESDTSRENKVQAKPPKVDGAEFWKSSPSILAVQRSAILKKQQQQQQQQQHQASSNSG 121
Query: 359 SSYDSGKNESVDRGAEDLSLNRGDEDEDDHEDHDDSEKVNETDG-VEAERLKA 410
S DS +E D + ++ + +DED S + +D E ER K+
Sbjct: 122 SEEDSSSSEDSDDSSSEVK-RKKHKDEDWQMSGSGSPSQSGSDSESEEEREKS 173
Score = 35.8 bits (81), Expect = 0.12
Identities = 44/235 (18%), Positives = 77/235 (32%), Gaps = 50/235 (21%)
Query: 207 LNSQQDEDESSIESDEFDMSDSTRMSAVNSDLSSNLEERMQSPQNLHGQQDDDSAAESFN 266
+N DE+ S E SD SA S S+ + G D DS +ES +
Sbjct: 1 MNGHSDEESVRNSSGESSQSDDDSGSASGSGSGSSSGSSSDGSSSQSGSSDSDSGSESGS 60
Query: 267 GNET-------------------------------LGHSSIASGGTHSREMGDSNSDGKT 295
+E+ + S+I ++ + +
Sbjct: 61 QSESESDTSRENKVQAKPPKVDGAEFWKSSPSILAVQRSAILKKQQQQQQQQQHQASSNS 120
Query: 296 GLEQDEQPLNLSDSPLSAQLTSEYRIDDHNSNGKNKYKNLLISDLKMEREARENGSKSPA 355
G E+D SD S +++ +D +G S + E+ E KS
Sbjct: 121 GSEEDSSSSEDSDDSSSEVKRKKHKDEDWQMSGSGSP-----SQSGSDSESEEEREKSSC 175
Query: 356 HSYSSYDSGKNESVDRGAEDLSLNRG--------------DEDEDDHEDHDDSEK 396
S KN+ R ++ S ++ E++DD ED+D+ ++
Sbjct: 176 DETESDYEPKNKVKSRKPQNRSKSKNGKKILGQKKRQIDSSEEDDDEEDYDNDKR 230
>gi|47106061 KRAB-A domain containing 2 [Homo sapiens]
Length = 492
Score = 36.2 bits (82), Expect = 0.095
Identities = 17/70 (24%), Positives = 32/70 (45%), Gaps = 8/70 (11%)
Query: 95 EKLSLRRVAVVEDFFDIIYSMHVETGPNGEQIRKHAGQKRTYKAISESYAFLPREAVTRF 154
E+ +R E+ FDI++ H+ G H G+ R K + Y + +E + +
Sbjct: 180 ERDRIRYYVHKEELFDILHDTHLSIG--------HGGRTRMLKELQGKYGNVTKEVIVLY 231
Query: 155 LMSCSECQKR 164
L C +C ++
Sbjct: 232 LTLCKQCHQK 241
>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo
sapiens]
Length = 1341
Score = 35.8 bits (81), Expect = 0.12
Identities = 60/295 (20%), Positives = 111/295 (37%), Gaps = 37/295 (12%)
Query: 232 SAVNSDLSSN--LEERMQSPQNLHGQQDDDSAAESFNGNETLGHSS---IASGGTHSREM 286
S + ++S N +++ ++ Q L Q+ + A E+ E S I G S
Sbjct: 125 SQIGEEMSQNSFIKQYLEKQQELLRQRLEREAREAAELEEASAESEDEMIHPEGVASLLP 184
Query: 287 GDSNSDGKTGLEQDEQPLNLSDSPLSAQLTSEYRIDDHNSNGKNKYKNLLISDLKMEREA 346
D S LE+ E L+ S+ ++ E D K + ++ S ++ R A
Sbjct: 185 PDFQSS----LERPELELSRHSPRKSSSISEEKGDSDDEKPRKGERRS---SRVRQARAA 237
Query: 347 RENGSKSPAHSYSSYDSGKNESVDRGAEDLSLNRGDEDEDDHEDHDDSEKVNETDGVEAE 406
+ + PA ++ R +L +E+E++ E+ DD E+ + +G ++
Sbjct: 238 KLSEGSQPAEEEEDQETPSRNLRVRADRNLKTEEEEEEEEE-EEEDDEEEEGDDEGQKS- 295
Query: 407 RLKAFNMFVRLFVDENLDRMVPISKQPKEKIQAIIDSCRRQFPEYQERARKRIRTYLKSC 466
R PI K+ KE+ + I + + + + R + + L+
Sbjct: 296 ------------------REAPILKEFKEEGEEIPRVKPEEMMDERPKTRSQEQEVLERG 337
Query: 467 RRMKRSGFEMSRPIPSHLTSAVAESIL--ASACESESRNAAKRMRLERQQDESAP 519
R RS E + SHL E + S E E R L+ + +P
Sbjct: 338 GRFTRSQEEARK---SHLARQQQEKEMKTTSPLEEEEREIKSSQGLKEKSKSPSP 389
>gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]
Length = 1682
Score = 35.8 bits (81), Expect = 0.12
Identities = 28/128 (21%), Positives = 59/128 (46%), Gaps = 5/128 (3%)
Query: 420 DENLDRMVPISKQPKEK--IQAIIDSCRRQFPEYQERARKRIRTYLKSCRRMKRSGFEMS 477
D +R++P ++ +E + A+ SC+R+ E+Q+ R+ R S R R G +
Sbjct: 946 DSGTERLLPPAQAKEEAGGVAAVSGSCKRRQKEHQKEHRRHRRACKDSVGRRPREGRAKA 1005
Query: 478 R-PIPSHLTSAVAESILASACESESRNAAK--RMRLERQQDESAPADKQCKPEATQATYS 534
+ +P + V ++ + E + R ++ + + +APA + Q T
Sbjct: 1006 KAKVPKEKSRRVLGNLDLQSEEIQGREKSRPDLGGASKAKPPTAPAPPSAPAPSAQPTPP 1065
Query: 535 TSAVPGSQ 542
+++VPG +
Sbjct: 1066 SASVPGKK 1073
>gi|55749769 CWC22 spliceosome-associated protein homolog [Homo
sapiens]
Length = 908
Score = 35.8 bits (81), Expect = 0.12
Identities = 33/123 (26%), Positives = 51/123 (41%), Gaps = 14/123 (11%)
Query: 336 LISDLKMEREARENGSKSPAHSYSSYDSGKNESVDRGAEDLSLNRGDEDEDDHEDHDDSE 395
+++ KM+ EN K A D G +S +D + DE+E++ E +D E
Sbjct: 381 VLNVFKMDPNFMENEEKYKAIKKEILDEGDTDS--NTDQDAGSSEEDEEEEEEEGEEDEE 438
Query: 396 --KVNETDGVEAERLKAFNMFVRLFVDENLD---------RMVPISKQPKEKIQAIIDSC 444
KV D E L +F + L + +LD +M Q KE I+D C
Sbjct: 439 GQKVTIHDKTEI-NLVSFRRTIYLAIQSSLDFEECAHKLLKMEFPESQTKELCNMILDCC 497
Query: 445 RRQ 447
+Q
Sbjct: 498 AQQ 500
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.127 0.351
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,972,852
Number of Sequences: 37866
Number of extensions: 1106975
Number of successful extensions: 6467
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 42
Number of HSP's successfully gapped in prelim test: 188
Number of HSP's that attempted gapping in prelim test: 5277
Number of HSP's gapped (non-prelim): 922
length of query: 638
length of database: 18,247,518
effective HSP length: 109
effective length of query: 529
effective length of database: 14,120,124
effective search space: 7469545596
effective search space used: 7469545596
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.