Guide to the Human Genome
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Name: ZAK Sequence: fasta or formatted (455aa) NCBI GI: 19526767
Description:

MLK-related kinase isoform 2

Referenced in:

MAP Kinase Pathways
Additional Interaction Domain Families

Other entries for this name:
alt prot [800aa] MLK-related kinase isoform 1
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.9         27           2
 C cysteine            1.8          8           1
 D aspartate           6.2         28           7
 E glutamate           9.5         43           3
 F phenylalanine       4.2         19           2
 G glycine             5.7         26           3
 H histidine           2.6         12           1
 I isoleucine          4.8         22           2
 K lysine              6.8         31           2
 L leucine             8.8         40           3
 M methionine          5.1         23           2
 N asparagine          4.6         21           1
 P proline             3.1         14           2
 Q glutamine           3.5         16           1
 R arginine            4.2         19           2
 S serine              9.9         45           2
 T threonine           4.2         19           2
 V valine              5.3         24           2
 W tryptophan          1.8          8           1
 Y tyrosine            2.2         10           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   MLK-related kinase isoform 2 
ZAK                   0.725   MLK-related kinase isoform 1 
MAP3K9                0.227   mitogen-activated protein kinase kinase kinase 9 [Ho...
MAP3K10               0.224   mitogen-activated protein kinase kinase kinase 10 [H...
KIAA1804              0.221   mixed lineage kinase 4 
MAP3K11               0.216   mitogen-activated protein kinase kinase kinase 11 [Ho...
MAP3K12               0.210   mitogen-activated protein kinase kinase kinase 12 [H...
MAP3K13               0.206   mitogen-activated protein kinase kinase kinase 13 [Ho...
MAP3K7                0.163   mitogen-activated protein kinase kinase kinase 7 iso...
MAP3K7                0.163   mitogen-activated protein kinase kinase kinase 7 isof...
MAP3K7                0.158   mitogen-activated protein kinase kinase kinase 7 iso...
MAP3K7                0.158   mitogen-activated protein kinase kinase kinase 7 iso...
ABL1                  0.144   c-abl oncogene 1, receptor tyrosine kinase isoform a...
ABL1                  0.144   c-abl oncogene 1, receptor tyrosine kinase isoform b...
ABL2                  0.141   arg tyrosine kinase isoform c 
ABL2                  0.141   arg tyrosine kinase isoform b 
ABL2                  0.141   arg tyrosine kinase isoform d 
ABL2                  0.141   arg tyrosine kinase isoform a 
ABL2                  0.141   arg tyrosine kinase isoform e 
FYN                   0.132   protein-tyrosine kinase fyn isoform a 
FRK                   0.132   fyn-related kinase 
TNNI3K                0.130   TNNI3 interacting kinase isoform b 
TNNI3K                0.130   TNNI3 interacting kinase isoform a 
TNK2                  0.129   tyrosine kinase, non-receptor, 2 isoform 1 
TNK2                  0.129   tyrosine kinase, non-receptor, 2 isoform 2 
BMX                   0.123   BMX non-receptor tyrosine kinase 
BMX                   0.123   BMX non-receptor tyrosine kinase 
FYN                   0.122   protein-tyrosine kinase fyn isoform b 
SRC                   0.120   proto-oncogene tyrosine-protein kinase SRC 
SRC                   0.120   proto-oncogene tyrosine-protein kinase SRC 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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