Search of human proteins with 147901383

Search of human proteins with 147901383

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|147901383 calcium channel, voltage-dependent, beta 2 subunit
isoform 5 [Homo sapiens]
         (622 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|147901383 calcium channel, voltage-dependent, beta 2 subunit ...  1234   0.0  
gi|45359842 calcium channel, voltage-dependent, beta 2 subunit i...  1212   0.0  
gi|147898681 calcium channel, voltage-dependent, beta 2 subunit ...  1207   0.0  
gi|147904948 calcium channel, voltage-dependent, beta 2 subunit ...  1139   0.0  
gi|148223541 calcium channel, voltage-dependent, beta 2 subunit ...  1134   0.0  
gi|148232726 calcium channel, voltage-dependent, beta 2 subunit ...  1074   0.0  
gi|45359834 calcium channel, voltage-dependent, beta 2 subunit i...  1073   0.0  
gi|148226485 calcium channel, voltage-dependent, beta 2 subunit ...  1073   0.0  
gi|40804468 calcium channel, voltage-dependent, beta 1 subunit i...   755   0.0  
gi|40804472 calcium channel, voltage-dependent, beta 1 subunit i...   698   0.0  
gi|40804470 calcium channel, voltage-dependent, beta 1 subunit i...   665   0.0  
gi|54607066 calcium channel, voltage-dependent, beta 4 subunit i...   657   0.0  
gi|54607064 calcium channel, voltage-dependent, beta 4 subunit i...   657   0.0  
gi|54607068 calcium channel, voltage-dependent, beta 4 subunit i...   639   0.0  
gi|224831262 calcium channel, voltage-dependent, beta 4 subunit ...   560   e-159
gi|40316928 calcium channel, voltage-dependent, beta 3 subunit [...   556   e-158
gi|50962882 G patch domain containing 8 [Homo sapiens]                 58   3e-08
gi|119943108 synapse-associated protein 102 isoform b [Homo sapi...    57   7e-08
gi|148539628 discs, large homolog 1 isoform 1 [Homo sapiens]           55   1e-07
gi|119943106 synapse-associated protein 102 isoform a [Homo sapi...    53   7e-07
gi|148539578 discs, large homolog 1 isoform 2 [Homo sapiens]           52   2e-06
gi|4504487 histidine rich calcium binding protein precursor [Hom...    50   5e-06
gi|218156338 chapsyn-110 isoform 1 [Homo sapiens]                      49   2e-05
gi|91199538 chapsyn-110 isoform 2 [Homo sapiens]                       49   2e-05
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        49   2e-05
gi|9945320 cyclin L1 [Homo sapiens]                                    48   3e-05
gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s...    47   4e-05
gi|218156340 chapsyn-110 isoform 3 [Homo sapiens]                      47   7e-05
gi|218156270 chapsyn-110 isoform 4 [Homo sapiens]                      47   7e-05
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ...    46   1e-04

>gi|147901383 calcium channel, voltage-dependent, beta 2 subunit
           isoform 5 [Homo sapiens]
          Length = 622

 Score = 1234 bits (3194), Expect = 0.0
 Identities = 622/622 (100%), Positives = 622/622 (100%)

Query: 1   MVQRDMSKSPPTAAAAVAQEIQMELLENVAPAGALGAAAQSYGKGARRKNRFKGSDGSTS 60
           MVQRDMSKSPPTAAAAVAQEIQMELLENVAPAGALGAAAQSYGKGARRKNRFKGSDGSTS
Sbjct: 1   MVQRDMSKSPPTAAAAVAQEIQMELLENVAPAGALGAAAQSYGKGARRKNRFKGSDGSTS 60

Query: 61  SDTTSNSFVRQGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVR 120
           SDTTSNSFVRQGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVR
Sbjct: 61  SDTTSNSFVRQGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVR 120

Query: 121 TNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLE 180
           TNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLE
Sbjct: 121 TNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLE 180

Query: 181 NMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAKQKQKSTEHTPPYDVV 240
           NMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAKQKQKSTEHTPPYDVV
Sbjct: 181 NMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAKQKQKSTEHTPPYDVV 240

Query: 241 PSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSK 300
           PSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSK
Sbjct: 241 PSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSK 300

Query: 301 HAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKI 360
           HAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKI
Sbjct: 301 HAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKI 360

Query: 361 SSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLE 420
           SSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLE
Sbjct: 361 SSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLE 420

Query: 421 AYWKATHPPSSSLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEE 480
           AYWKATHPPSSSLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEE
Sbjct: 421 AYWKATHPPSSSLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEE 480

Query: 481 EPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDH 540
           EPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDH
Sbjct: 481 EPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDH 540

Query: 541 VDHYASHRDHNHRDETHGSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKD 600
           VDHYASHRDHNHRDETHGSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKD
Sbjct: 541 VDHYASHRDHNHRDETHGSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKD 600

Query: 601 GEVISKKRNEAGEWNRDVYIRQ 622
           GEVISKKRNEAGEWNRDVYIRQ
Sbjct: 601 GEVISKKRNEAGEWNRDVYIRQ 622


>gi|45359842 calcium channel, voltage-dependent, beta 2 subunit
           isoform 4 [Homo sapiens]
          Length = 636

 Score = 1212 bits (3135), Expect = 0.0
 Identities = 615/636 (96%), Positives = 617/636 (97%), Gaps = 14/636 (2%)

Query: 1   MVQRDMSKSPPTAAAAVAQEIQMELLENVAPAGALGAAAQSYGKGARRKNRFKGSDGSTS 60
           MVQRDMSKSPPTAAAAVAQEIQMELLENVAPAGALGAAAQSYGKGARRKNRFKGSDGSTS
Sbjct: 1   MVQRDMSKSPPTAAAAVAQEIQMELLENVAPAGALGAAAQSYGKGARRKNRFKGSDGSTS 60

Query: 61  SDTTSNSFVRQGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVR 120
           SDTTSNSFVRQGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVR
Sbjct: 61  SDTTSNSFVRQGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVR 120

Query: 121 TNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLE 180
           TNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLE
Sbjct: 121 TNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLE 180

Query: 181 NMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAKQKQK----------- 229
           NMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSS  +              
Sbjct: 181 NMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSGAKSADEQDQWKTAGLF 240

Query: 230 ---STEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTAD 286
              +TEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTAD
Sbjct: 241 WRFTTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTAD 300

Query: 287 ISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQL 346
           ISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQL
Sbjct: 301 ISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQL 360

Query: 347 SKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDEN 406
           SKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDEN
Sbjct: 361 SKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDEN 420

Query: 407 QLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRT 466
           QLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRT
Sbjct: 421 QLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRT 480

Query: 467 DRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRD 526
           DRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRD
Sbjct: 481 DRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRD 540

Query: 527 SAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHRSRDVDREQDHNECNKQ 586
           SAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHRSRDVDREQDHNECNKQ
Sbjct: 541 SAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHRSRDVDREQDHNECNKQ 600

Query: 587 RSRHKSKDRYCEKDGEVISKKRNEAGEWNRDVYIRQ 622
           RSRHKSKDRYCEKDGEVISKKRNEAGEWNRDVYIRQ
Sbjct: 601 RSRHKSKDRYCEKDGEVISKKRNEAGEWNRDVYIRQ 636


>gi|147898681 calcium channel, voltage-dependent, beta 2 subunit
           isoform 2 [Homo sapiens]
          Length = 660

 Score = 1207 bits (3123), Expect = 0.0
 Identities = 619/660 (93%), Positives = 621/660 (94%), Gaps = 38/660 (5%)

Query: 1   MVQRDMSKSPPTAAAAVAQEIQMELLENVAPAGALGAAAQSYGKGARRKNRFKGSDGSTS 60
           MVQRDMSKSPPTAAAAVAQEIQMELLENVAPAGALGAAAQSYGKGARRKNRFKGSDGSTS
Sbjct: 1   MVQRDMSKSPPTAAAAVAQEIQMELLENVAPAGALGAAAQSYGKGARRKNRFKGSDGSTS 60

Query: 61  SDTTSNSFVRQGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVR 120
           SDTTSNSFVRQGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVR
Sbjct: 61  SDTTSNSFVRQGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVR 120

Query: 121 TNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLE 180
           TNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLE
Sbjct: 121 TNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLE 180

Query: 181 NMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSA---------------- 224
           NMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSA                
Sbjct: 181 NMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEENDIP 240

Query: 225 ------------------KQKQ----KSTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMM 262
                             K+K+    K TEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMM
Sbjct: 241 ANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMM 300

Query: 263 QKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIER 322
           QKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIER
Sbjct: 301 QKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIER 360

Query: 323 IFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLN 382
           IFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLN
Sbjct: 361 IFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLN 420

Query: 383 VQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTL 442
           VQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTL
Sbjct: 421 VQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTL 480

Query: 443 ATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHN 502
           ATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHN
Sbjct: 481 ATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHN 540

Query: 503 HRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDH 562
           HRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDH
Sbjct: 541 HRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDH 600

Query: 563 RHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRDVYIRQ 622
           RHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRDVYIRQ
Sbjct: 601 RHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRDVYIRQ 660


>gi|147904948 calcium channel, voltage-dependent, beta 2 subunit
           isoform 8 [Homo sapiens]
          Length = 608

 Score = 1139 bits (2945), Expect = 0.0
 Identities = 575/596 (96%), Positives = 577/596 (96%), Gaps = 14/596 (2%)

Query: 41  SYGKGARRKNRFKGSDGSTSSDTTSNSFVRQGSADSYTSRPSDSDVSLEEDREAVRREAE 100
           SYGKGARRKNRFKGSDGSTSSDTTSNSFVRQGSADSYTSRPSDSDVSLEEDREAVRREAE
Sbjct: 13  SYGKGARRKNRFKGSDGSTSSDTTSNSFVRQGSADSYTSRPSDSDVSLEEDREAVRREAE 72

Query: 101 RQAQAQLEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWI 160
           RQAQAQLEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWI
Sbjct: 73  RQAQAQLEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWI 132

Query: 161 GRLVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTP 220
           GRLVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTP
Sbjct: 133 GRLVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTP 192

Query: 221 PSSAKQKQK--------------STEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKAL 266
           PSS  +                 +TEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKAL
Sbjct: 193 PSSGAKSADEQDQWKTAGLFWRFTTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKAL 252

Query: 267 FDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFEL 326
           FDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFEL
Sbjct: 253 FDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFEL 312

Query: 327 ARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMV 386
           ARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMV
Sbjct: 313 ARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMV 372

Query: 387 AADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSS 446
           AADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSS
Sbjct: 373 AADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSS 432

Query: 447 LPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSG 506
           LPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSG
Sbjct: 433 LPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSG 492

Query: 507 TSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRE 566
           TSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRE
Sbjct: 493 TSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRE 552

Query: 567 SRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRDVYIRQ 622
           SRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRDVYIRQ
Sbjct: 553 SRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRDVYIRQ 608


>gi|148223541 calcium channel, voltage-dependent, beta 2 subunit
           isoform 6 [Homo sapiens]
          Length = 632

 Score = 1134 bits (2933), Expect = 0.0
 Identities = 579/620 (93%), Positives = 581/620 (93%), Gaps = 38/620 (6%)

Query: 41  SYGKGARRKNRFKGSDGSTSSDTTSNSFVRQGSADSYTSRPSDSDVSLEEDREAVRREAE 100
           SYGKGARRKNRFKGSDGSTSSDTTSNSFVRQGSADSYTSRPSDSDVSLEEDREAVRREAE
Sbjct: 13  SYGKGARRKNRFKGSDGSTSSDTTSNSFVRQGSADSYTSRPSDSDVSLEEDREAVRREAE 72

Query: 101 RQAQAQLEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWI 160
           RQAQAQLEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWI
Sbjct: 73  RQAQAQLEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWI 132

Query: 161 GRLVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTP 220
           GRLVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTP
Sbjct: 133 GRLVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTP 192

Query: 221 PSSA----------------------------------KQKQ----KSTEHTPPYDVVPS 242
           PSSA                                  K+K+    K TEHTPPYDVVPS
Sbjct: 193 PSSAIDIDATGLDAEENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPS 252

Query: 243 MRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHA 302
           MRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHA
Sbjct: 253 MRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHA 312

Query: 303 IIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISS 362
           IIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISS
Sbjct: 313 IIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISS 372

Query: 363 PKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAY 422
           PKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAY
Sbjct: 373 PKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAY 432

Query: 423 WKATHPPSSSLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEP 482
           WKATHPPSSSLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEP
Sbjct: 433 WKATHPPSSSLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEP 492

Query: 483 SVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVD 542
           SVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVD
Sbjct: 493 SVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVD 552

Query: 543 HYASHRDHNHRDETHGSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKDGE 602
           HYASHRDHNHRDETHGSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKDGE
Sbjct: 553 HYASHRDHNHRDETHGSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKDGE 612

Query: 603 VISKKRNEAGEWNRDVYIRQ 622
           VISKKRNEAGEWNRDVYIRQ
Sbjct: 613 VISKKRNEAGEWNRDVYIRQ 632


>gi|148232726 calcium channel, voltage-dependent, beta 2 subunit
           isoform 1 [Homo sapiens]
          Length = 605

 Score = 1074 bits (2777), Expect = 0.0
 Identities = 549/592 (92%), Positives = 551/592 (93%), Gaps = 38/592 (6%)

Query: 69  VRQGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAA 128
           V  GSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAA
Sbjct: 14  VSYGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAA 73

Query: 129 HEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQ 188
           HEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQ
Sbjct: 74  HEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQ 133

Query: 189 RAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSA------------------------ 224
           RAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSA                        
Sbjct: 134 RAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEENDIPANHRSPKP 193

Query: 225 ----------KQKQ----KSTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFL 270
                     K+K+    K TEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFL
Sbjct: 194 SANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFL 253

Query: 271 KHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTL 330
           KHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTL
Sbjct: 254 KHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTL 313

Query: 331 QLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADK 390
           QLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADK
Sbjct: 314 QLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADK 373

Query: 391 LAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLS 450
           LAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLS
Sbjct: 374 LAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLS 433

Query: 451 PTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRG 510
           PTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRG
Sbjct: 434 PTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRG 493

Query: 511 LSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHR 570
           LSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHR
Sbjct: 494 LSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHR 553

Query: 571 SRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRDVYIRQ 622
           SRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRDVYIRQ
Sbjct: 554 SRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRDVYIRQ 605


>gi|45359834 calcium channel, voltage-dependent, beta 2 subunit
           isoform 7 [Homo sapiens]
          Length = 612

 Score = 1073 bits (2775), Expect = 0.0
 Identities = 548/589 (93%), Positives = 550/589 (93%), Gaps = 38/589 (6%)

Query: 72  GSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAAHED 131
           GSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAAHED
Sbjct: 24  GSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAAHED 83

Query: 132 DVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAK 191
           DVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAK
Sbjct: 84  DVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAK 143

Query: 192 QGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSA--------------------------- 224
           QGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSA                           
Sbjct: 144 QGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEENDIPANHRSPKPSAN 203

Query: 225 -------KQKQ----KSTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHR 273
                  K+K+    K TEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHR
Sbjct: 204 SVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHR 263

Query: 274 FEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLV 333
           FEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLV
Sbjct: 264 FEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLV 323

Query: 334 VLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQ 393
           VLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQ
Sbjct: 324 VLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQ 383

Query: 394 CPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPTL 453
           CPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPTL
Sbjct: 384 CPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPTL 443

Query: 454 ASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSR 513
           ASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSR
Sbjct: 444 ASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSR 503

Query: 514 QETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHRSRD 573
           QETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHRSRD
Sbjct: 504 QETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHRSRD 563

Query: 574 VDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRDVYIRQ 622
           VDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRDVYIRQ
Sbjct: 564 VDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRDVYIRQ 612


>gi|148226485 calcium channel, voltage-dependent, beta 2 subunit
           isoform 3 [Homo sapiens]
          Length = 606

 Score = 1073 bits (2775), Expect = 0.0
 Identities = 548/589 (93%), Positives = 550/589 (93%), Gaps = 38/589 (6%)

Query: 72  GSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAAHED 131
           GSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAAHED
Sbjct: 18  GSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAAHED 77

Query: 132 DVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAK 191
           DVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAK
Sbjct: 78  DVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAK 137

Query: 192 QGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSA--------------------------- 224
           QGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSA                           
Sbjct: 138 QGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEENDIPANHRSPKPSAN 197

Query: 225 -------KQKQ----KSTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHR 273
                  K+K+    K TEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHR
Sbjct: 198 SVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHR 257

Query: 274 FEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLV 333
           FEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLV
Sbjct: 258 FEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLV 317

Query: 334 VLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQ 393
           VLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQ
Sbjct: 318 VLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQ 377

Query: 394 CPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPTL 453
           CPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPTL
Sbjct: 378 CPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPTL 437

Query: 454 ASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSR 513
           ASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSR
Sbjct: 438 ASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSR 497

Query: 514 QETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHRSRD 573
           QETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHRSRD
Sbjct: 498 QETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHRSRD 557

Query: 574 VDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRDVYIRQ 622
           VDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRDVYIRQ
Sbjct: 558 VDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRDVYIRQ 606


>gi|40804468 calcium channel, voltage-dependent, beta 1 subunit
           isoform 1 [Homo sapiens]
          Length = 598

 Score =  755 bits (1949), Expect = 0.0
 Identities = 407/626 (65%), Positives = 473/626 (75%), Gaps = 33/626 (5%)

Query: 1   MVQR-DMSKSPPTAAAAVAQEIQMELLENVAPAGALGAAAQSYGKGARRKNRFKGSDGST 59
           MVQ+  MS+ P   +    QEI ME+ +               GK ++RK RFK SDGST
Sbjct: 1   MVQKTSMSRGPYPPS----QEIPMEVFD-----------PSPQGKYSKRKGRFKRSDGST 45

Query: 60  SSDTTSNSFVRQGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAV 119
           SSDTTSNSFVRQGSA+SYTSRPSDSDVSLEEDREA+R+EAERQA AQLEKAKTKPVAFAV
Sbjct: 46  SSDTTSNSFVRQGSAESYTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAV 105

Query: 120 RTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKL 179
           RTNV Y+ +  D+VPV G+AI+FE KDFLH+KEK+NNDWWIGRLVKEGCE+GFIPSPVKL
Sbjct: 106 RTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKL 165

Query: 180 ENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAKQKQKSTEHTPPYDV 239
           +++RL  EQ+ +Q +  SSKSG NSSSSLGD+V  +R+ TPP+SAKQKQKSTEH PPYDV
Sbjct: 166 DSLRLLQEQKLRQNRLGSSKSGDNSSSSLGDVVTGTRRPTPPASAKQKQKSTEHVPPYDV 225

Query: 240 VPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPS 299
           VPSMRP++LVGPSLKGYEVTDMMQKALFDFLKHRF+GRISITRVTADISLAKRSVLNNPS
Sbjct: 226 VPSMRPIILVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPS 285

Query: 300 KHAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVK 359
           KH IIERSNTRSSLAEVQSEIERIFELARTLQLV LDADTINHPAQLSKTSLAPIIVY+K
Sbjct: 286 KHIIIERSNTRSSLAEVQSEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIVYIK 345

Query: 360 ISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYL 419
           I+SPKVLQRLIKSRGKSQ+KHLNVQ+ A++KLAQCPPE+FD+ILDENQLEDACEHLA+YL
Sbjct: 346 ITSPKVLQRLIKSRGKSQSKHLNVQIAASEKLAQCPPEMFDIILDENQLEDACEHLAEYL 405

Query: 420 EAYWKATHPPSSSLPNPLLSRTLATSSLPLSPTLASNSQG---SQGDQRTDRSAPIRSAS 476
           EAYWKATHPPSS+ PNPLL+RT+AT++L  SP   SN QG   + GDQ      P+  A+
Sbjct: 406 EAYWKATHPPSSTPPNPLLNRTMATAALAASPAPVSNLQGPYLASGDQ------PLERAT 459

Query: 477 QAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDY 536
                    P +  Q      + H   R+GT R LSRQ+TFD++T  SR+SAY E     
Sbjct: 460 GEHASMHEYPGELGQPPGLYPSSHPPGRAGTLRALSRQDTFDADTPGSRNSAYTE----L 515

Query: 537 SHDHVDHYASHRDHNHRDETHGSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRY 596
               VD      +     +  G      R+      + D E+   E    R+R ++K RY
Sbjct: 516 GDSCVDMETDPSEGPGLGDPAGGGTPPARQGSWEDEEEDYEE---ELTDNRNRGRNKARY 572

Query: 597 C-EKDGEVISKKRNEAGEWNRDVYIR 621
           C E  G V+ + +NE   W R VYIR
Sbjct: 573 CAEGGGPVLGRNKNELEGWGRGVYIR 598


>gi|40804472 calcium channel, voltage-dependent, beta 1 subunit
           isoform 3 [Homo sapiens]
          Length = 478

 Score =  698 bits (1801), Expect = 0.0
 Identities = 356/459 (77%), Positives = 401/459 (87%), Gaps = 16/459 (3%)

Query: 1   MVQR-DMSKSPPTAAAAVAQEIQMELLENVAPAGALGAAAQSYGKGARRKNRFKGSDGST 59
           MVQ+  MS+ P   +    QEI ME+ +               GK ++RK RFK SDGST
Sbjct: 1   MVQKTSMSRGPYPPS----QEIPMEVFD-----------PSPQGKYSKRKGRFKRSDGST 45

Query: 60  SSDTTSNSFVRQGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAV 119
           SSDTTSNSFVRQGSA+SYTSRPSDSDVSLEEDREA+R+EAERQA AQLEKAKTKPVAFAV
Sbjct: 46  SSDTTSNSFVRQGSAESYTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAV 105

Query: 120 RTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKL 179
           RTNV Y+ +  D+VPV G+AI+FE KDFLH+KEK+NNDWWIGRLVKEGCE+GFIPSPVKL
Sbjct: 106 RTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKL 165

Query: 180 ENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAKQKQKSTEHTPPYDV 239
           +++RL  EQ+ +Q +  SSKSG NSSSSLGD+V  +R+ TPP+SAKQKQKSTEH PPYDV
Sbjct: 166 DSLRLLQEQKLRQNRLGSSKSGDNSSSSLGDVVTGTRRPTPPASAKQKQKSTEHVPPYDV 225

Query: 240 VPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPS 299
           VPSMRP++LVGPSLKGYEVTDMMQKALFDFLKHRF+GRISITRVTADISLAKRSVLNNPS
Sbjct: 226 VPSMRPIILVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPS 285

Query: 300 KHAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVK 359
           KH IIERSNTRSSLAEVQSEIERIFELARTLQLV LDADTINHPAQLSKTSLAPIIVY+K
Sbjct: 286 KHIIIERSNTRSSLAEVQSEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIVYIK 345

Query: 360 ISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYL 419
           I+SPKVLQRLIKSRGKSQ+KHLNVQ+ A++KLAQCPPE+FD+ILDENQLEDACEHLA+YL
Sbjct: 346 ITSPKVLQRLIKSRGKSQSKHLNVQIAASEKLAQCPPEMFDIILDENQLEDACEHLAEYL 405

Query: 420 EAYWKATHPPSSSLPNPLLSRTLATSSLPLSPTLASNSQ 458
           EAYWKATHPPSS+ PNPLL+RT+AT++L  SP   SN Q
Sbjct: 406 EAYWKATHPPSSTPPNPLLNRTMATAALAASPAPVSNLQ 444


>gi|40804470 calcium channel, voltage-dependent, beta 1 subunit
           isoform 2 [Homo sapiens]
          Length = 523

 Score =  665 bits (1717), Expect = 0.0
 Identities = 350/504 (69%), Positives = 396/504 (78%), Gaps = 61/504 (12%)

Query: 1   MVQR-DMSKSPPTAAAAVAQEIQMELLENVAPAGALGAAAQSYGKGARRKNRFKGSDGST 59
           MVQ+  MS+ P   +    QEI ME+ +               GK ++RK RFK SDGST
Sbjct: 1   MVQKTSMSRGPYPPS----QEIPMEVFD-----------PSPQGKYSKRKGRFKRSDGST 45

Query: 60  SSDTTSNSFVRQGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAV 119
           SSDTTSNSFVRQGSA+SYTSRPSDSDVSLEEDREA+R+EAERQA AQLEKAKTKPVAFAV
Sbjct: 46  SSDTTSNSFVRQGSAESYTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAV 105

Query: 120 RTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKL 179
           RTNV Y+ +  D+VPV G+AI+FE KDFLH+KEK+NNDWWIGRLVKEGCE+GFIPSPVKL
Sbjct: 106 RTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKL 165

Query: 180 ENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAKQKQ----------- 228
           +++RL  EQ+ +Q +  SSKSG NSSSSLGD+V  +R+ TPP+S  +             
Sbjct: 166 DSLRLLQEQKLRQNRLGSSKSGDNSSSSLGDVVTGTRRPTPPASGNEMTNLAFELDPLEL 225

Query: 229 ----------------------------------KSTEHTPPYDVVPSMRPVVLVGPSLK 254
                                             K TEH PPYDVVPSMRP++LVGPSLK
Sbjct: 226 EEEEAELGEQSGSAKTSVSSVTTPPPHGKRIPFFKKTEHVPPYDVVPSMRPIILVGPSLK 285

Query: 255 GYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLA 314
           GYEVTDMMQKALFDFLKHRF+GRISITRVTADISLAKRSVLNNPSKH IIERSNTRSSLA
Sbjct: 286 GYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLA 345

Query: 315 EVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRG 374
           EVQSEIERIFELARTLQLV LDADTINHPAQLSKTSLAPIIVY+KI+SPKVLQRLIKSRG
Sbjct: 346 EVQSEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRG 405

Query: 375 KSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLP 434
           KSQ+KHLNVQ+ A++KLAQCPPE+FD+ILDENQLEDACEHLA+YLEAYWKATHPPSS+ P
Sbjct: 406 KSQSKHLNVQIAASEKLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTPP 465

Query: 435 NPLLSRTLATSSLPLSPTLASNSQ 458
           NPLL+RT+AT++L  SP   SN Q
Sbjct: 466 NPLLNRTMATAALAASPAPVSNLQ 489


>gi|54607066 calcium channel, voltage-dependent, beta 4 subunit
           isoform c [Homo sapiens]
          Length = 502

 Score =  657 bits (1695), Expect = 0.0
 Identities = 355/524 (67%), Positives = 409/524 (78%), Gaps = 34/524 (6%)

Query: 48  RKNRFKGSDGSTSSDTTSNSFV-RQGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQ 106
           R++R K SDGST    TS SF+ RQGSADSYTSRPSDSDVSLEEDREA+R+E E+QA  Q
Sbjct: 11  RRSRLKRSDGST----TSTSFILRQGSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQ 66

Query: 107 LEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKE 166
           LE+AK+KPVAFAV+TNVSY  A ++DVPVP  AISF+AKDFLH+KEK+NNDWWIGRLVKE
Sbjct: 67  LERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKE 126

Query: 167 GCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAKQ 226
           GCEIGFIPSP++LEN+R+Q EQ  K+G+F+  KS GNSSSSLG++V  + ++TP S+AKQ
Sbjct: 127 GCEIGFIPSPLRLENIRIQQEQ--KRGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTAKQ 184

Query: 227 KQKSTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTAD 286
           KQK TEH PPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRF+GRISITRVTAD
Sbjct: 185 KQKVTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTAD 244

Query: 287 ISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQL 346
           ISLAKRSVLNNPSK AIIERSNTRSSLAEVQSEIERIFELAR+LQLVVLDADTINHPAQL
Sbjct: 245 ISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIFELARSLQLVVLDADTINHPAQL 304

Query: 347 SKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDEN 406
            KTSLAPIIV+VK+SSPKVLQRLIKSRGKSQ+KHLNVQ+VAADKLAQCPPE+FDVILDEN
Sbjct: 305 IKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQCPPEMFDVILDEN 364

Query: 407 QLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRT 466
           QLEDACEHL +YLEAYW+ATH  SS+   PLL R L +++L   PT  S  Q        
Sbjct: 365 QLEDACEHLGEYLEAYWRATHTTSSTPMTPLLGRNLGSTALSPYPTAISGLQ-------- 416

Query: 467 DRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRD 526
             S  +R ++ + E   +E     +   +S   +HN R+  SR         S +Q SRD
Sbjct: 417 --SQRMRHSNHSTENSPIE----RRSLMTSDENYHNERARKSR-----NRLSSSSQHSRD 465

Query: 527 SAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHR 570
             Y   +EDY   + D Y  HR+        GS      +SRHR
Sbjct: 466 H-YPLVEEDYPDSYQDTYKPHRN-------RGSPGGYSHDSRHR 501


>gi|54607064 calcium channel, voltage-dependent, beta 4 subunit
           isoform b [Homo sapiens]
          Length = 520

 Score =  657 bits (1695), Expect = 0.0
 Identities = 355/524 (67%), Positives = 409/524 (78%), Gaps = 34/524 (6%)

Query: 48  RKNRFKGSDGSTSSDTTSNSFV-RQGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQ 106
           R++R K SDGST    TS SF+ RQGSADSYTSRPSDSDVSLEEDREA+R+E E+QA  Q
Sbjct: 29  RRSRLKRSDGST----TSTSFILRQGSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQ 84

Query: 107 LEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKE 166
           LE+AK+KPVAFAV+TNVSY  A ++DVPVP  AISF+AKDFLH+KEK+NNDWWIGRLVKE
Sbjct: 85  LERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKE 144

Query: 167 GCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAKQ 226
           GCEIGFIPSP++LEN+R+Q EQ  K+G+F+  KS GNSSSSLG++V  + ++TP S+AKQ
Sbjct: 145 GCEIGFIPSPLRLENIRIQQEQ--KRGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTAKQ 202

Query: 227 KQKSTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTAD 286
           KQK TEH PPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRF+GRISITRVTAD
Sbjct: 203 KQKVTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTAD 262

Query: 287 ISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQL 346
           ISLAKRSVLNNPSK AIIERSNTRSSLAEVQSEIERIFELAR+LQLVVLDADTINHPAQL
Sbjct: 263 ISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIFELARSLQLVVLDADTINHPAQL 322

Query: 347 SKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDEN 406
            KTSLAPIIV+VK+SSPKVLQRLIKSRGKSQ+KHLNVQ+VAADKLAQCPPE+FDVILDEN
Sbjct: 323 IKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQCPPEMFDVILDEN 382

Query: 407 QLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRT 466
           QLEDACEHL +YLEAYW+ATH  SS+   PLL R L +++L   PT  S  Q        
Sbjct: 383 QLEDACEHLGEYLEAYWRATHTTSSTPMTPLLGRNLGSTALSPYPTAISGLQ-------- 434

Query: 467 DRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRD 526
             S  +R ++ + E   +E     +   +S   +HN R+  SR         S +Q SRD
Sbjct: 435 --SQRMRHSNHSTENSPIE----RRSLMTSDENYHNERARKSR-----NRLSSSSQHSRD 483

Query: 527 SAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHR 570
             Y   +EDY   + D Y  HR+        GS      +SRHR
Sbjct: 484 H-YPLVEEDYPDSYQDTYKPHRN-------RGSPGGYSHDSRHR 519


>gi|54607068 calcium channel, voltage-dependent, beta 4 subunit
           isoform a [Homo sapiens]
          Length = 486

 Score =  639 bits (1649), Expect = 0.0
 Identities = 341/499 (68%), Positives = 392/499 (78%), Gaps = 29/499 (5%)

Query: 72  GSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAAHED 131
           GSADSYTSRPSDSDVSLEEDREA+R+E E+QA  QLE+AK+KPVAFAV+TNVSY  A ++
Sbjct: 16  GSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDE 75

Query: 132 DVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAK 191
           DVPVP  AISF+AKDFLH+KEK+NNDWWIGRLVKEGCEIGFIPSP++LEN+R+Q EQ  K
Sbjct: 76  DVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQ--K 133

Query: 192 QGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAKQKQKSTEHTPPYDVVPSMRPVVLVGP 251
           +G+F+  KS GNSSSSLG++V  + ++TP S+AKQKQK TEH PPYDVVPSMRPVVLVGP
Sbjct: 134 RGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSMRPVVLVGP 193

Query: 252 SLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRS 311
           SLKGYEVTDMMQKALFDFLKHRF+GRISITRVTADISLAKRSVLNNPSK AIIERSNTRS
Sbjct: 194 SLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRS 253

Query: 312 SLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIK 371
           SLAEVQSEIERIFELAR+LQLVVLDADTINHPAQL KTSLAPIIV+VK+SSPKVLQRLIK
Sbjct: 254 SLAEVQSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIK 313

Query: 372 SRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSS 431
           SRGKSQ+KHLNVQ+VAADKLAQCPPE+FDVILDENQLEDACEHL +YLEAYW+ATH  SS
Sbjct: 314 SRGKSQSKHLNVQLVAADKLAQCPPEMFDVILDENQLEDACEHLGEYLEAYWRATHTTSS 373

Query: 432 SLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQ 491
           +   PLL R L +++L   PT  S  Q          S  +R ++ + E   +E     +
Sbjct: 374 TPMTPLLGRNLGSTALSPYPTAISGLQ----------SQRMRHSNHSTENSPIE----RR 419

Query: 492 HRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHN 551
              +S   +HN R+  SR         S +Q SRD  Y   +EDY   + D Y  HR+  
Sbjct: 420 SLMTSDENYHNERARKSR-----NRLSSSSQHSRDH-YPLVEEDYPDSYQDTYKPHRN-- 471

Query: 552 HRDETHGSSDHRHRESRHR 570
                 GS      +SRHR
Sbjct: 472 -----RGSPGGYSHDSRHR 485


>gi|224831262 calcium channel, voltage-dependent, beta 4 subunit
           isoform d [Homo sapiens]
          Length = 458

 Score =  560 bits (1443), Expect = e-159
 Identities = 320/524 (61%), Positives = 367/524 (70%), Gaps = 96/524 (18%)

Query: 48  RKNRFKGSDGSTSSDTTSNSFV-RQGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQ 106
           R++R K SDGST    TS SF+ RQGSADSYTSRPSDSDVSLEEDREA+R+E E+QA  Q
Sbjct: 29  RRSRLKRSDGST----TSTSFILRQGSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQ 84

Query: 107 LEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKE 166
           LE+AK+KPVAFAV+TNVSY  A ++DVPVP  AISF+AKDFLH+KEK+NNDWWIGRLVKE
Sbjct: 85  LERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKE 144

Query: 167 GCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAKQ 226
           GCEIGFIPSP++LEN+R+Q EQ  K+G+F+  KS GNSSSSLG++V  + ++TP S+AKQ
Sbjct: 145 GCEIGFIPSPLRLENIRIQQEQ--KRGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTAKQ 202

Query: 227 KQKSTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTAD 286
           KQK TEH PPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRF+GRISITRVTAD
Sbjct: 203 KQKVTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTAD 262

Query: 287 ISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQL 346
           ISLAKRSVLNNPSK AIIERSNTRSSLAEVQSEIERIFELAR+LQLVVLDADTINHPAQL
Sbjct: 263 ISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIFELARSLQLVVLDADTINHPAQL 322

Query: 347 SKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDEN 406
            KTSLAPIIV+VK+SSPKVLQRLIKSRGKSQ+KHLNVQ+VAADKLAQCPP          
Sbjct: 323 IKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQCPPS--------- 373

Query: 407 QLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRT 466
                            +  H   S+  +P+  R+L TS                     
Sbjct: 374 ----------------QRMRHSNHSTENSPIERRSLMTS--------------------- 396

Query: 467 DRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRD 526
                       +E    E  +KS++R SSS+ H                       SRD
Sbjct: 397 ------------DENYHNERARKSRNRLSSSSQH-----------------------SRD 421

Query: 527 SAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHR 570
             Y   +EDY   + D Y  HR+        GS      +SRHR
Sbjct: 422 H-YPLVEEDYPDSYQDTYKPHRN-------RGSPGGYSHDSRHR 457


>gi|40316928 calcium channel, voltage-dependent, beta 3 subunit
           [Homo sapiens]
          Length = 484

 Score =  556 bits (1434), Expect = e-158
 Identities = 312/527 (59%), Positives = 367/527 (69%), Gaps = 60/527 (11%)

Query: 72  GSADSYTSRPS-DSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAAHE 130
           GSADSYTSRPS DSDVSLEEDRE+ RRE E QAQ QLE+AK KPVAFAVRTNVSY    +
Sbjct: 16  GSADSYTSRPSLDSDVSLEEDRESARREVESQAQQQLERAKHKPVAFAVRTNVSYCGVLD 75

Query: 131 DDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRA 190
           ++ PV G  ++FEAKDFLH+KEK++NDWWIGRLVKEG +I FIPSP +LE++RL+ EQ+A
Sbjct: 76  EECPVQGSGVNFEAKDFLHIKEKYSNDWWIGRLVKEGGDIAFIPSPQRLESIRLKQEQKA 135

Query: 191 KQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAKQKQKSTEHTPPYDVVPSMRPVVLVG 250
           ++           + SSL DI   +R+S PPS AKQKQK  EH PPYDVVPSMRPVVLVG
Sbjct: 136 RRS---------GNPSSLSDI--GNRRSPPPSLAKQKQKQAEHVPPYDVVPSMRPVVLVG 184

Query: 251 PSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTR 310
           PSLKGYEVTDMMQKALFDFLKHRF+GRISITRVTAD+SLAKRSVLNNP K  IIERS+ R
Sbjct: 185 PSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADLSLAKRSVLNNPGKRTIIERSSAR 244

Query: 311 SSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLI 370
           SS+AEVQSEIERIFELA++LQLVVLDADTINHPAQL+KTSLAPIIV+VK+SSPKVLQRLI
Sbjct: 245 SSIAEVQSEIERIFELAKSLQLVVLDADTINHPAQLAKTSLAPIIVFVKVSSPKVLQRLI 304

Query: 371 KSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPS 430
           +SRGKSQ KHL VQM+A DKL QCPPE FDVILDENQLEDACEHLA+YLE YW+ATH P+
Sbjct: 305 RSRGKSQMKHLTVQMMAYDKLVQCPPESFDVILDENQLEDACEHLAEYLEVYWRATHHPA 364

Query: 431 SSLPNP-LLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKK 489
              P P LL    A   L     L     G +G++ +                   P+++
Sbjct: 365 ---PGPGLLGPPSAIPGLQNQQLL-----GERGEEHS-------------------PLER 397

Query: 490 SQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRD 549
                S  A   + ++ T                 R S ++E  EDY+  + D Y  HR 
Sbjct: 398 DSLMPSDEASESSRQAWTG-------------SSQRSSRHLE--EDYADAYQDLYQPHRQ 442

Query: 550 HNHRDETHGSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRY 596
           H     T G       + + R    D E +H++ N QR+R   KD Y
Sbjct: 443 H-----TSGLPSANGHDPQDRLLAQDSEHNHSDRNWQRNRPWPKDSY 484


>gi|50962882 G patch domain containing 8 [Homo sapiens]
          Length = 1502

 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 49/182 (26%), Positives = 74/182 (40%), Gaps = 30/182 (16%)

Query: 457 SQGSQGDQRTDRSAPIR----SASQAEEEPSVEP--VKKSQHRSSSSAPHHNHRSGTSRG 510
           SQ S GD+ +D ++  R    S SQ  EE   E    + S+ RS S   H +HRS     
Sbjct: 811 SQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSS---- 866

Query: 511 LSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYA------SHRDHNHRDETHGSSDHRH 564
              + ++ S +  S D +    +  YS D    Y+      S R H+  D  + SS HR 
Sbjct: 867 ---RRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRS 923

Query: 565 RESRHRSRDVD----------REQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEW 614
           +  ++ S D D          R + H    + RSR +S+   C +       +   A  W
Sbjct: 924 KRHKYSSSDDDYSLSCSQSRSRSRSHTR-ERSRSRGRSRSSSCSRSRSKRRSRSTTAHSW 982

Query: 615 NR 616
            R
Sbjct: 983 QR 984



 Score = 33.1 bits (74), Expect = 0.78
 Identities = 36/146 (24%), Positives = 55/146 (37%), Gaps = 8/146 (5%)

Query: 455 SNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQ 514
           S S+   G + +   +  RS S + +  S +    S+ RS S   + ++   + R   R 
Sbjct: 850 SRSRSRSGRRHSSHRSSRRSYSSSSDASSDQSCY-SRQRSYSDDSYSDYSDRSRRHSKRS 908

Query: 515 ETFD-----SETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRH 569
              D     S    S+   Y    +DYS       +  R  +H  E   S       S  
Sbjct: 909 HDSDDSDYASSKHRSKRHKYSSSDDDYSLS--CSQSRSRSRSHTRERSRSRGRSRSSSCS 966

Query: 570 RSRDVDREQDHNECNKQRSRHKSKDR 595
           RSR   R +     + QRSR  S+DR
Sbjct: 967 RSRSKRRSRSTTAHSWQRSRSYSRDR 992


>gi|119943108 synapse-associated protein 102 isoform b [Homo
           sapiens]
          Length = 512

 Score = 56.6 bits (135), Expect = 7e-08
 Identities = 71/334 (21%), Positives = 129/334 (38%), Gaps = 61/334 (18%)

Query: 132 DVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVK---EGCEIGFIPSPVKLE-------- 180
           D  +P   +SF   D LHV    +++WW  RLV    E  +IG IPS  ++E        
Sbjct: 180 DSCLPSQGLSFSYGDILHVINASDDEWWQARLVTPHGESEQIGVIPSKKRVEKKERARLK 239

Query: 181 ------------------NMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPS 222
                               R +  + +++  FY SK      SS+ +   +S  S   S
Sbjct: 240 TVKFHARTGMIESNRSIKTKRKKSFRLSRKFPFYKSKENMAQESSIQEQGVTSNTSDSES 299

Query: 223 SAKQKQKSTEHTPPY--DVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRI-S 279
           S+K ++ +     P     +   RPV+++GP      + D +   L     H+F   +  
Sbjct: 300 SSKGQEDAILSYEPVTRQEIHYARPVIILGP------MKDRVNDDLISEFPHKFGSCVPH 353

Query: 280 ITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQ-------------SEIERIFEL 326
            TR   D      + ++    H ++ R      + + +             + I+ +  +
Sbjct: 354 TTRPRRD------NEVDGQDYHFVVSREQMEKDIQDNKFIEAGQFNDNLYGTSIQSVRAV 407

Query: 327 ARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMV 386
           A   +  +LD    N   +L +  L PI +++K   PK ++ L++   +   +  N    
Sbjct: 408 AERGKHCILDVSG-NAIKRLQQAQLYPIAIFIK---PKSIEALMEMNRRQTYEQANKIYD 463

Query: 387 AADKLAQCPPELFDVILDENQLEDACEHLADYLE 420
            A KL Q   E F  I+  + LE+    +   +E
Sbjct: 464 KAMKLEQEFGEYFTAIVQGDSLEEIYNKIKQIIE 497


>gi|148539628 discs, large homolog 1 isoform 1 [Homo sapiens]
          Length = 904

 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 68/308 (22%), Positives = 121/308 (39%), Gaps = 34/308 (11%)

Query: 132 DVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVK---EGCEIGFIPSPVKLENMRLQHEQ 188
           D  +P   ++F+  D LHV    +++WW  R V    E  E+G IPS  ++E    +   
Sbjct: 597 DSGLPSQGLNFKFGDILHVINASDDEWWQARQVTPDGESDEVGVIPSKRRVEK---KERA 653

Query: 189 RAKQGKFYS-SKSGGNSSSSLGDIVPSSRKSTPPSSAKQKQKSTEHTPPYDVVPSM---- 243
           R K  KF S ++  G     +G        S    S    +   E+   Y+ V       
Sbjct: 654 RLKTVKFNSKTRDKGEIPDDMGSKGLKHVTSNASDSESSYRGQEEYVLSYEPVNQQEVNY 713

Query: 244 -RPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRI-SITRVTADISL---------AKR 292
            RPV+++GP      + D +   L      +F   +   TR   D  +         ++ 
Sbjct: 714 TRPVIILGP------MKDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVTSRE 767

Query: 293 SVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLA 352
            +  +  +H  IE     + L    + ++ + E+A   +  +LD    N   +L    L 
Sbjct: 768 QMEKDIQEHKFIEAGQYNNHL--YGTSVQSVREVAEKGKHCILDVSG-NAIKRLQIAQLY 824

Query: 353 PIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDAC 412
           PI +++K   PK ++ +++   +   +        A KL Q   E F  I+  + LED  
Sbjct: 825 PISIFIK---PKSMENIMEMNKRLTEEQARKTFERAMKLEQEFTEHFTAIVQGDTLEDIY 881

Query: 413 EHLADYLE 420
             +   +E
Sbjct: 882 NQVKQIIE 889


>gi|119943106 synapse-associated protein 102 isoform a [Homo
           sapiens]
          Length = 817

 Score = 53.1 bits (126), Expect = 7e-07
 Identities = 68/311 (21%), Positives = 121/311 (38%), Gaps = 47/311 (15%)

Query: 132 DVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVK---EGCEIGFIPSPVKLENMRLQHEQ 188
           D  +P   +SF   D LHV    +++WW  RLV    E  +IG IPS  ++E    +   
Sbjct: 517 DSCLPSQGLSFSYGDILHVINASDDEWWQARLVTPHGESEQIGVIPSKKRVEK---KERA 573

Query: 189 RAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAKQKQKSTEHTPPYDVVPSM----- 243
           R K  KF++      S+     +      S     AK  +   +    Y+ V        
Sbjct: 574 RLKTVKFHARTGMIESNRDFPGL------SDDYYGAKNLKGQEDAILSYEPVTRQEIHYA 627

Query: 244 RPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRI-SITRVTADISLAKRSVLNNPSKHA 302
           RPV+++GP      + D +   L     H+F   +   TR   D      + ++    H 
Sbjct: 628 RPVIILGP------MKDRVNDDLISEFPHKFGSCVPHTTRPRRD------NEVDGQDYHF 675

Query: 303 IIERSNTRSSLAEVQ-------------SEIERIFELARTLQLVVLDADTINHPAQLSKT 349
           ++ R      + + +             + I+ +  +A   +  +LD    N   +L + 
Sbjct: 676 VVSREQMEKDIQDNKFIEAGQFNDNLYGTSIQSVRAVAERGKHCILDVSG-NAIKRLQQA 734

Query: 350 SLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLE 409
            L PI +++K   PK ++ L++   +   +  N     A KL Q   E F  I+  + LE
Sbjct: 735 QLYPIAIFIK---PKSIEALMEMNRRQTYEQANKIYDKAMKLEQEFGEYFTAIVQGDSLE 791

Query: 410 DACEHLADYLE 420
           +    +   +E
Sbjct: 792 EIYNKIKQIIE 802


>gi|148539578 discs, large homolog 1 isoform 2 [Homo sapiens]
          Length = 926

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 68/327 (20%), Positives = 127/327 (38%), Gaps = 50/327 (15%)

Query: 132 DVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVK---EGCEIGFIPSPVKLE-------- 180
           D  +P   ++F+  D LHV    +++WW  R V    E  E+G IPS  ++E        
Sbjct: 597 DSGLPSQGLNFKFGDILHVINASDDEWWQARQVTPDGESDEVGVIPSKRRVEKKERARLK 656

Query: 181 ---------------NMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAK 225
                          N + +    +++  FY +K      +S  D   +S  S   SS +
Sbjct: 657 TVKFNSKTRDKGQSFNDKRKKNLFSRKFPFYKNKDQSEQETSDADQHVTSNASDSESSYR 716

Query: 226 QKQKSTEHTPPYD--VVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRI-SITR 282
            +++      P +   V   RPV+++GP      + D +   L      +F   +   TR
Sbjct: 717 GQEEYVLSYEPVNQQEVNYTRPVIILGP------MKDRINDDLISEFPDKFGSCVPHTTR 770

Query: 283 VTADISL---------AKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLV 333
              D  +         ++  +  +  +H  IE     + L    + ++ + E+A   +  
Sbjct: 771 PKRDYEVDGRDYHFVTSREQMEKDIQEHKFIEAGQYNNHL--YGTSVQSVREVAEKGKHC 828

Query: 334 VLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQ 393
           +LD    N   +L    L PI +++K   PK ++ +++   +   +        A KL Q
Sbjct: 829 ILDVSG-NAIKRLQIAQLYPISIFIK---PKSMENIMEMNKRLTEEQARKTFERAMKLEQ 884

Query: 394 CPPELFDVILDENQLEDACEHLADYLE 420
              E F  I+  + LED    +   +E
Sbjct: 885 EFTEHFTAIVQGDTLEDIYNQVKQIIE 911


>gi|4504487 histidine rich calcium binding protein precursor [Homo
           sapiens]
          Length = 699

 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 41/148 (27%), Positives = 60/148 (40%), Gaps = 9/148 (6%)

Query: 476 SQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAY--VEPK 533
           S  + E   E V K            +H+ G   G+S +E F     ++R       E  
Sbjct: 84  SHPDREKEDEDVSKEYGHLLPGHRSQDHKVG-DEGVSGEEVFAEHGGQARGHRGHGSEDT 142

Query: 534 EDYSHDHVDHYASHRDHNHRDETHG---SSDHRHRESRHRSRDVDREQDHNECNKQRSRH 590
           ED S +H  H  SHR H+H+DE      SS+H H   RH  R  D E D  E  ++    
Sbjct: 143 ED-SAEHRHHLPSHRSHSHQDEDEDEVVSSEHHHHILRHGHRGHDGEDDEGE--EEEEEE 199

Query: 591 KSKDRYCEKDGEVISKKRNEAGEWNRDV 618
           + ++    + G    + R    E + DV
Sbjct: 200 EEEEEASTEYGHQAHRHRGHGSEEDEDV 227



 Score = 38.9 bits (89), Expect = 0.014
 Identities = 33/141 (23%), Positives = 53/141 (37%), Gaps = 16/141 (11%)

Query: 463 DQRTDRSAPIRSASQAEEEPSVEPVKKS-QHRSSSS------APHHNHRSGTSRGLSRQE 515
           D   D         + EEE S E   ++ +HR   S      +  H+H   + R    +E
Sbjct: 186 DGEDDEGEEEEEEEEEEEEASTEYGHQAHRHRGHGSEEDEDVSDGHHHHGPSHRHQGHEE 245

Query: 516 TFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHRSR--- 572
             D +  +  D    +  +D S ++      H+ H   ++   S  H HR+  HR R   
Sbjct: 246 DDDDDDDDDDD----DDDDDVSIEYRHQAHRHQGHGIEEDEDVSDGHHHRDPSHRHRSHE 301

Query: 573 --DVDREQDHNECNKQRSRHK 591
             D D +    E   Q  RH+
Sbjct: 302 EDDNDDDDVSTEYGHQAHRHQ 322



 Score = 33.5 bits (75), Expect = 0.60
 Identities = 23/100 (23%), Positives = 37/100 (37%), Gaps = 6/100 (6%)

Query: 501 HNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSS 560
           H+HR  + R  S +E  + +   S +  +       +H H DH     +    +  H   
Sbjct: 288 HHHRDPSHRHRSHEEDDNDDDDVSTEYGH------QAHRHQDHRKEEVEAVSGEHHHHVP 341

Query: 561 DHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKD 600
           DHRH+  R    D D   +      Q   H   D   E++
Sbjct: 342 DHRHQGHRDEEEDEDVSTERWHQGPQHVHHGLVDEEEEEE 381



 Score = 30.8 bits (68), Expect = 3.9
 Identities = 25/126 (19%), Positives = 48/126 (38%), Gaps = 8/126 (6%)

Query: 470 APIRSASQAEEEPSVEPVKKSQHRSSSSAPHH--NHRSGTSRGLSRQETFDSETQESRDS 527
           AP    S  +EE         Q  S     HH   H     R   R++  + E ++  D 
Sbjct: 438 APSHRQSHQDEETG-----HGQRGSIKEMSHHPPGHTVVKDRSHLRKDDSEEEKEKEEDP 492

Query: 528 AYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHRSRDVDREQDHNECNKQR 587
              E ++D S +  +    H   +  DE      H    ++    + D+E++  E +++R
Sbjct: 493 GSHE-EDDESSEQGEKGTHHGSRDQEDEEDEEEGHGLSLNQEEEEEEDKEEEEEEEDEER 551

Query: 588 SRHKSK 593
              +++
Sbjct: 552 REERAE 557


>gi|218156338 chapsyn-110 isoform 1 [Homo sapiens]
          Length = 975

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 76/324 (23%), Positives = 127/324 (39%), Gaps = 51/324 (15%)

Query: 119 VRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVK---EGCEIGFIPS 175
           VR    Y  + +  +P  G+  SF+  D LHV    +++WW  R V    +  E+G IPS
Sbjct: 646 VRAMFDYDKSKDSGLPSQGL--SFKYGDILHVINASDDEWWQARRVMLEGDSEEMGVIPS 703

Query: 176 PVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPS----SRKSTPPSSAKQKQKST 231
             ++E    +   R K  KF +     +S  S  D        SRK   P    ++Q   
Sbjct: 704 KRRVER---KERARLKTVKFNAKPGVIDSKGSFNDKRKKSFIFSRKF--PFYKNKEQSEQ 758

Query: 232 EHTPP----------YDVVPSM-----RPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEG 276
           E + P          Y+ V        RPV+++GP      + D +   L      +F  
Sbjct: 759 ETSDPERGQEDLILSYEPVTRQEINYTRPVIILGP------MKDRINDDLISEFPDKFGS 812

Query: 277 RI-SITRVTADIS---------LAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFEL 326
            +   TR   D           +++  +  +  +H  IE      +L    + ++ +  +
Sbjct: 813 CVPHTTRPKRDYEVDGRDYHFVISREQMEKDIQEHKFIEAGQYNDNL--YGTSVQSVRFV 870

Query: 327 ARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMV 386
           A   +  +LD    N   +L    L PI +++K  S + L  + K   + QAK    + +
Sbjct: 871 AERGKHCILDVSG-NAIKRLQVAQLYPIAIFIKPRSLEPLMEMNKRLTEEQAKKTYDRAI 929

Query: 387 AADKLAQCPPELFDVILDENQLED 410
              KL Q   E F  I+  + LED
Sbjct: 930 ---KLEQEFGEYFTAIVQGDTLED 950


>gi|91199538 chapsyn-110 isoform 2 [Homo sapiens]
          Length = 870

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 76/324 (23%), Positives = 127/324 (39%), Gaps = 51/324 (15%)

Query: 119 VRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVK---EGCEIGFIPS 175
           VR    Y  + +  +P  G+  SF+  D LHV    +++WW  R V    +  E+G IPS
Sbjct: 541 VRAMFDYDKSKDSGLPSQGL--SFKYGDILHVINASDDEWWQARRVMLEGDSEEMGVIPS 598

Query: 176 PVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPS----SRKSTPPSSAKQKQKST 231
             ++E    +   R K  KF +     +S  S  D        SRK   P    ++Q   
Sbjct: 599 KRRVER---KERARLKTVKFNAKPGVIDSKGSFNDKRKKSFIFSRKF--PFYKNKEQSEQ 653

Query: 232 EHTPP----------YDVVPSM-----RPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEG 276
           E + P          Y+ V        RPV+++GP      + D +   L      +F  
Sbjct: 654 ETSDPERGQEDLILSYEPVTRQEINYTRPVIILGP------MKDRINDDLISEFPDKFGS 707

Query: 277 RI-SITRVTADIS---------LAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFEL 326
            +   TR   D           +++  +  +  +H  IE      +L    + ++ +  +
Sbjct: 708 CVPHTTRPKRDYEVDGRDYHFVISREQMEKDIQEHKFIEAGQYNDNL--YGTSVQSVRFV 765

Query: 327 ARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMV 386
           A   +  +LD    N   +L    L PI +++K  S + L  + K   + QAK    + +
Sbjct: 766 AERGKHCILDVSG-NAIKRLQVAQLYPIAIFIKPRSLEPLMEMNKRLTEEQAKKTYDRAI 824

Query: 387 AADKLAQCPPELFDVILDENQLED 410
              KL Q   E F  I+  + LED
Sbjct: 825 ---KLEQEFGEYFTAIVQGDTLED 845


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 47/177 (26%), Positives = 68/177 (38%), Gaps = 17/177 (9%)

Query: 429 PSSSLPNPLLSRTLATSSLPLSPTLASN---SQGSQGDQRTDRSAPI------RSASQAE 479
           P    P PLL+     S  PL+ T  S    +  S+     DRS P       +S+S   
Sbjct: 361 PEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSES 420

Query: 480 EEPSVEPVKKSQHRSSS-SAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSH 538
             PS +P K S+H SSS  +P      G+ R +S   T       S++ ++   K D SH
Sbjct: 421 SPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPT-------SKNRSHGRAKRDKSH 473

Query: 539 DHVDHYASHRDHNHRDETHGSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDR 595
            H       R  +      G S  R    R  SR    +   +   ++  R +S  R
Sbjct: 474 SHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQR 530



 Score = 35.8 bits (81), Expect = 0.12
 Identities = 30/136 (22%), Positives = 56/136 (41%), Gaps = 11/136 (8%)

Query: 429 PSSSLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVK 488
           P+   P P      ++SS   +P      +     +R++ S+P R   ++         K
Sbjct: 163 PAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSS--------K 214

Query: 489 KSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHR 548
           K +HRS S +    HRS T +  S++++ D + + SR S    PK   +H      ++  
Sbjct: 215 KKKHRSESESKKRKHRSPTPK--SKRKSKDKKRKRSR-STTPAPKSRRAHRSTSADSASS 271

Query: 549 DHNHRDETHGSSDHRH 564
               R  +  ++   H
Sbjct: 272 SDTSRSRSRSAAAKTH 287



 Score = 34.7 bits (78), Expect = 0.27
 Identities = 42/187 (22%), Positives = 69/187 (36%), Gaps = 21/187 (11%)

Query: 429  PSSSLPNPLLSRTLA-TSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPV 487
            P +  P  L  R+ + +SS    P+   +S      +   +S   R  S++  EP  +  
Sbjct: 1624 PKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSR 1683

Query: 488  KKSQHRSSSSAPHHNHRSGTSRGLSRQETFDSET--------QESRDSAYVEPKEDYSHD 539
               + RSS S+P    ++  SR  SR  +   ET        + S   +  EP E     
Sbjct: 1684 TPPRRRSSRSSPELTRKARLSR-RSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSS 1742

Query: 540  HVDHYA--------SHRDHNHRDETHGSSDHRHRESRHRSRDV---DREQDHNECNKQRS 588
                 A        S R  +   +  G    R R  R ++R     DR       +++R 
Sbjct: 1743 RRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQ 1802

Query: 589  RHKSKDR 595
            R +S+ R
Sbjct: 1803 RSRSRSR 1809



 Score = 32.7 bits (73), Expect = 1.0
 Identities = 28/93 (30%), Positives = 40/93 (43%), Gaps = 18/93 (19%)

Query: 430 SSSLPNPLLSRTLATSSLPLSPTLASNS---------------QGSQGDQRTDRSAPIRS 474
           S SL +P   R+ A S L L  +L+ +S                GS   +   R+ P RS
Sbjct: 759 SRSLSSP---RSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRS 815

Query: 475 ASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGT 507
            S +   P  +    S+   SSS+PH   +SGT
Sbjct: 816 RSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGT 848



 Score = 32.0 bits (71), Expect = 1.7
 Identities = 38/154 (24%), Positives = 59/154 (38%), Gaps = 14/154 (9%)

Query: 450  SPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGT-- 507
            SP    +S+ S   +R     P  S  ++    S  P K+S+ R +S A H   RS T  
Sbjct: 1824 SPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSR-ASPATHRRSRSRTPL 1882

Query: 508  -SRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNH-----RDETHGSSD 561
             SR  SR  T     + SR    V  +   S       +  R  +      R  +   + 
Sbjct: 1883 ISRRRSRSRTSPVSRRRSRSRTSVTRRR--SRSRASPVSRRRSRSRTPPVTRRRSRSRTP 1940

Query: 562  HRHRESRHRSRDVDREQDHNE---CNKQRSRHKS 592
               R SR R+  V R +  +      ++RSR ++
Sbjct: 1941 TTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRT 1974



 Score = 30.0 bits (66), Expect = 6.6
 Identities = 28/120 (23%), Positives = 47/120 (39%), Gaps = 16/120 (13%)

Query: 425  ATHPPSSSLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIR---------SA 475
            A  P      +   S + ++SS   S + +S+S GS        S P++         S 
Sbjct: 2523 ALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSP 2582

Query: 476  SQAEEE-------PSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSA 528
            + A +E       P   P K+ +  SSSS+   +  S +S   S   +  S +  S  S+
Sbjct: 2583 TPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2642


>gi|9945320 cyclin L1 [Homo sapiens]
          Length = 526

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 36/142 (25%), Positives = 62/142 (43%), Gaps = 16/142 (11%)

Query: 454 ASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSR 513
           AS S  +   + + RS   RSAS++          +S+ RS +   H+N+R       SR
Sbjct: 371 ASKSPYNGVRKDSKRSRNSRSASRSRSRT------RSRSRSHTPRRHYNNRR------SR 418

Query: 514 QETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHRSRD 573
             T+ S ++    S    P+  ++H      A H     RD+   S+ H H+  + RSR 
Sbjct: 419 SGTYSSRSRSRSRSHSESPRRHHNHGSPHLKAKHT----RDDLKSSNRHGHKRKKSRSRS 474

Query: 574 VDREQDHNECNKQRSRHKSKDR 595
             + +DH++  K+    +   R
Sbjct: 475 QSKSRDHSDAAKKHRHERGHHR 496


>gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
           sapiens]
          Length = 434

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 38/151 (25%), Positives = 64/151 (42%), Gaps = 12/151 (7%)

Query: 478 AEEEPSVEPVKKSQHRSSSSAPHHN-HRSGTSRGLSRQETFDSETQESRDSAYVEPKEDY 536
           A E+ S +  KK +    S +P  + H    SR  SR+    S+ +  +  +    KE  
Sbjct: 12  APEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGR 71

Query: 537 SHDHVDHYA-SHRDHNHRDETHGSSDHRHR-------ESRH--RSRDVDREQDHNECNKQ 586
            H+  D  +  H+   H D+ H S   R R       E RH  + R   R + H+    +
Sbjct: 72  RHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSR 131

Query: 587 RSRHKSKDRYCEKDGEVISKKRNEAGEWNRD 617
             RH+S+ R   K     S++R ++   +R+
Sbjct: 132 ERRHRSRSRE-RKKSRSRSRERKKSRSRSRE 161



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 39/177 (22%), Positives = 72/177 (40%), Gaps = 28/177 (15%)

Query: 467 DRSAPIRSASQAEEEPSVEPVKKSQH-------------RSSSSAPHHNHRSGTSRGLSR 513
           ++++P R   + + E SV P     H             +S +    H  RS +  G  R
Sbjct: 14  EKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEG-RR 72

Query: 514 QETFDSETQESRDSAY--VEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRH-----RE 566
            E+ D  +++ +   +   E   D   + ++   +  D + R E   S    H     RE
Sbjct: 73  HESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRE 132

Query: 567 SRHRSRDVDREQDHNEC-------NKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNR 616
            RHRSR  +R++  +         ++ R R KS+ R  E+   + S+ R+ +   +R
Sbjct: 133 RRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHR 189



 Score = 36.2 bits (82), Expect = 0.093
 Identities = 42/170 (24%), Positives = 64/170 (37%), Gaps = 18/170 (10%)

Query: 455 SNSQGSQGDQRTDRSA-PIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSR 513
           S S+  +  +++D      RS S+++E    E   KS  +  S   H++    + +G  R
Sbjct: 43  SRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEE-HNDKEHSSDKG--R 99

Query: 514 QETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRE------- 566
           +    SE  E R     E K      H    +  R H  R      S  R RE       
Sbjct: 100 ERLNSSENGEDRHKRK-ERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSR 158

Query: 567 ------SRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNE 610
                 SR RSR+  R       ++ R RH+++ R   +      KKR E
Sbjct: 159 SRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIE 208


>gi|218156340 chapsyn-110 isoform 3 [Homo sapiens]
          Length = 749

 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 71/307 (23%), Positives = 123/307 (40%), Gaps = 35/307 (11%)

Query: 119 VRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVK---EGCEIGFIPS 175
           VR    Y  + +  +P  G+  SF+  D LHV    +++WW  R V    +  E+G IPS
Sbjct: 438 VRAMFDYDKSKDSGLPSQGL--SFKYGDILHVINASDDEWWQARRVMLEGDSEEMGVIPS 495

Query: 176 PVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAKQKQKSTEHTP 235
             ++E    +   R K  KF ++K G     S GDI           + + ++       
Sbjct: 496 KRRVER---KERARLKTVKF-NAKPG--VIDSKGDIPGLGDDGYGTKTLRGQEDLILSYE 549

Query: 236 PY--DVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRI-SITRVTADIS---- 288
           P     +   RPV+++GP      + D +   L      +F   +   TR   D      
Sbjct: 550 PVTRQEINYTRPVIILGP------MKDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDGR 603

Query: 289 -----LAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHP 343
                +++  +  +  +H  IE      +L    + ++ +  +A   +  +LD    N  
Sbjct: 604 DYHFVISREQMEKDIQEHKFIEAGQYNDNL--YGTSVQSVRFVAERGKHCILDVSG-NAI 660

Query: 344 AQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVIL 403
            +L    L PI +++K  S + L  + K   + QAK    + +   KL Q   E F  I+
Sbjct: 661 KRLQVAQLYPIAIFIKPRSLEPLMEMNKRLTEEQAKKTYDRAI---KLEQEFGEYFTAIV 717

Query: 404 DENQLED 410
             + LED
Sbjct: 718 QGDTLED 724


>gi|218156270 chapsyn-110 isoform 4 [Homo sapiens]
          Length = 334

 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 71/307 (23%), Positives = 123/307 (40%), Gaps = 35/307 (11%)

Query: 119 VRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVK---EGCEIGFIPS 175
           VR    Y  + +  +P  G+  SF+  D LHV    +++WW  R V    +  E+G IPS
Sbjct: 23  VRAMFDYDKSKDSGLPSQGL--SFKYGDILHVINASDDEWWQARRVMLEGDSEEMGVIPS 80

Query: 176 PVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAKQKQKSTEHTP 235
             ++E    +   R K  KF ++K G     S GDI           + + ++       
Sbjct: 81  KRRVER---KERARLKTVKF-NAKPG--VIDSKGDIPGLGDDGYGTKTLRGQEDLILSYE 134

Query: 236 PY--DVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRI-SITRVTADIS---- 288
           P     +   RPV+++GP      + D +   L      +F   +   TR   D      
Sbjct: 135 PVTRQEINYTRPVIILGP------MKDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDGR 188

Query: 289 -----LAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHP 343
                +++  +  +  +H  IE      +L    + ++ +  +A   +  +LD    N  
Sbjct: 189 DYHFVISREQMEKDIQEHKFIEAGQYNDNL--YGTSVQSVRFVAERGKHCILDVSG-NAI 245

Query: 344 AQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVIL 403
            +L    L PI +++K  S + L  + K   + QAK    + +   KL Q   E F  I+
Sbjct: 246 KRLQVAQLYPIAIFIKPRSLEPLMEMNKRLTEEQAKKTYDRAI---KLEQEFGEYFTAIV 302

Query: 404 DENQLED 410
             + LED
Sbjct: 303 QGDTLED 309


>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
           containing B [Homo sapiens]
          Length = 546

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 42/167 (25%), Positives = 61/167 (36%), Gaps = 20/167 (11%)

Query: 459 GSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFD 518
           G +G +  DR    R +       S+ P  +   R S S  HH    G+S    R+   +
Sbjct: 244 GKEGAEEIDRHVERRRSRSPRR--SLSP--RRSPRRSRSRSHHREGHGSS-SFDRELERE 298

Query: 519 SETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHRSRDVDREQ 578
            E Q     A    KE      +D     R    R+     S  R R+   R RD +RE+
Sbjct: 299 KERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREK 358

Query: 579 DH---------------NECNKQRSRHKSKDRYCEKDGEVISKKRNE 610
           ++               NE  K+R R + + +     GEV  KK  E
Sbjct: 359 ENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKE 405



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 49/184 (26%), Positives = 69/184 (37%), Gaps = 38/184 (20%)

Query: 464 QRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGT---------------- 507
           QR +R A  R   + E   S    +  + R S S   H  RS +                
Sbjct: 302 QRLEREAKER---EKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREK 358

Query: 508 --SRGLSRQETFD----SETQESRDSAYVEPKEDYSHDHVD---HYASHRDHNHRDETHG 558
              RG  R   +D    +E ++ R+ +    KE  S   V+   H     D  HRD+   
Sbjct: 359 ENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRD 418

Query: 559 S------SDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAG 612
           S      S  R RE +HRSR   R    N   + RSR K K    + + +  S KR+ +G
Sbjct: 419 SKKEKKHSRSRSRERKHRSRSRSR----NAGKRSRSRSKEKSSKHKNESKEKSNKRSRSG 474

Query: 613 EWNR 616
              R
Sbjct: 475 SQGR 478



 Score = 35.0 bits (79), Expect = 0.21
 Identities = 36/174 (20%), Positives = 65/174 (37%), Gaps = 18/174 (10%)

Query: 456 NSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQE 515
           N +  + ++  +RS   RS  + EE+   E     +HR          +   SR   R+ 
Sbjct: 376 NEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKH 435

Query: 516 TFDSETQESRDSAYVEPKEDYS-HDHVDHYASHR-----DHNHRDETHGSSDHRHRES-- 567
              S ++ +   +    KE  S H +     S++          D    S    H  S  
Sbjct: 436 RSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKE 495

Query: 568 ----RHRSRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRD 617
               R RS++   ++DH++   Q  +H   DR   +  + I ++  E    N+D
Sbjct: 496 KSRKRSRSKERSHKRDHSDSKDQSDKH---DR---RRSQSIEQESQEKQHKNKD 543



 Score = 34.7 bits (78), Expect = 0.27
 Identities = 34/157 (21%), Positives = 61/157 (38%), Gaps = 8/157 (5%)

Query: 455 SNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQ 514
           S S+  +GD+R DR       ++       +  K+  +           RS   R  SR 
Sbjct: 340 SRSRDRKGDRR-DRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQR--SRG 396

Query: 515 ETFDSETQESRDSA-YVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHRSRD 573
           E  + + +E +D   + + K D   +     +  R+  HR      S  R+   R RSR 
Sbjct: 397 EVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSR----SRSRNAGKRSRSRS 452

Query: 574 VDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNE 610
            ++   H   +K++S  +S+     +   V   K+ E
Sbjct: 453 KEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKRE 489



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 38/171 (22%), Positives = 62/171 (36%), Gaps = 11/171 (6%)

Query: 440 RTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAP 499
           R+L+    P      S+ +   G    DR        Q  E  + E  ++ + R S S  
Sbjct: 265 RSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKE--REKERRRSRSID 322

Query: 500 HHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGS 559
                 G  R  SR          SRD        D   +  +     RD ++ D+  G+
Sbjct: 323 R-----GLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDY-DKERGN 376

Query: 560 SDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNE 610
              + RE   RSR+  +EQ      +++   + KD    +D +  SKK  +
Sbjct: 377 EREKERE---RSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKK 424


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.125    0.350 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,708,685
Number of Sequences: 37866
Number of extensions: 1093772
Number of successful extensions: 7479
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 111
Number of HSP's successfully gapped in prelim test: 267
Number of HSP's that attempted gapping in prelim test: 5624
Number of HSP's gapped (non-prelim): 1422
length of query: 622
length of database: 18,247,518
effective HSP length: 108
effective length of query: 514
effective length of database: 14,157,990
effective search space: 7277206860
effective search space used: 7277206860
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.