Guide to the Human Genome
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Name: NLRP1 Sequence: fasta or formatted (1473aa) NCBI GI: 14719829
Description:

NLR family, pyrin domain containing 1 isoform 1

Referenced in:

BCL2 Pathways, Caspases, and Programmed Cell Death
Pyrin and Associated Functions

Other entries for this name:
alt prot [1443aa] NLR family, pyrin domain containing 1 isoform 3
alt prot [1399aa] NLR family, pyrin domain containing 1 isoform 4
alt prot [1375aa] NLR family, pyrin domain containing 1 isoform 5
alt prot [1429aa] NLR family, pyrin domain containing 1 isoform 2
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.2         92           2
 C cysteine            2.4         36           2
 D aspartate           3.9         58           3
 E glutamate           7.7        113           2
 F phenylalanine       3.5         51           2
 G glycine             6.0         88           2
 H histidine           3.3         49           3
 I isoleucine          3.5         51           2
 K lysine              4.8         70           2
 L leucine            13.9        205           4
 M methionine          2.0         29           1
 N asparagine          1.7         25           2
 P proline             6.7         98           3
 Q glutamine           5.6         82           2
 R arginine            5.8         86           2
 S serine              8.1        120           3
 T threonine           5.2         76           4
 V valine              5.6         83           2
 W tryptophan          2.1         31           1
 Y tyrosine            2.0         30           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   NLR family, pyrin domain containing 1 isoform 1 [Hom... 
NLRP1                 0.976   NLR family, pyrin domain containing 1 isoform 3 [Hom...
NLRP1                 0.962   NLR family, pyrin domain containing 1 isoform 2 [Homo...
NLRP1                 0.938   NLR family, pyrin domain containing 1 isoform 4 [Hom...
NLRP1                 0.918   NLR family, pyrin domain containing 1 isoform 5 [Hom...
NLRP12                0.157   NLR family, pyrin domain containing 12 isoform 2 [Ho...
NLRP3                 0.148   NLR family, pyrin domain containing 3 isoform c [Ho...
NLRP3                 0.147   NLR family, pyrin domain containing 3 isoform a [Ho...
NLRP3                 0.147   NLR family, pyrin domain containing 3 isoform a [Hom...
NLRP3                 0.143   NLR family, pyrin domain containing 3 isoform b [Hom...
NLRP3                 0.141   NLR family, pyrin domain containing 3 isoform d [Ho...
NLRP14                0.135   NLR family, pyrin domain containing 14 
NLRP13                0.106   NACHT, leucine rich repeat and PYD containing 13 [H...
NLRP9                 0.106   NLR family, pyrin domain containing 9 
NLRP2                 0.104   NLR family, pyrin domain containing 2 
NLRP7                 0.103   NACHT, leucine rich repeat and PYD containing 7 isof...
NLRP4                 0.101   NLR family, pyrin domain containing 4 
NLRP5                 0.100   NACHT, LRR and PYD containing protein 5 
NLRP7                 0.099   NACHT, leucine rich repeat and PYD containing 7 iso...
NLRP7                 0.099   NACHT, leucine rich repeat and PYD containing 7 isof...
NLRP6                 0.097   NLR family, pyrin domain containing 6 
CARD8                 0.094   caspase recruitment domain family, member 8 
NLRP8                 0.086   NLR family, pyrin domain containing 8 
NLRP10                0.076   NLR family, pyrin domain containing 10 
NLRP11                0.076   NLR family, pyrin domain containing 11 
NLRP12                0.042   NLR family, pyrin domain containing 12 isoform 1 [Ho...
RNH1                  0.039   ribonuclease/angiogenin inhibitor 
RNH1                  0.039   ribonuclease/angiogenin inhibitor 
RNH1                  0.039   ribonuclease/angiogenin inhibitor 
RNH1                  0.039   ribonuclease/angiogenin inhibitor 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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