Guide to the Human Genome
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Name: NLRP3 Sequence: fasta or formatted (979aa) NCBI GI: 188536116
Description:

NLR family, pyrin domain containing 3 isoform c

Referenced in:

Pyrin and Associated Functions

Other entries for this name:
alt prot [1036aa] NLR family, pyrin domain containing 3 isoform a
alt prot [979aa] NLR family, pyrin domain containing 3 isoform d
alt prot [922aa] NLR family, pyrin domain containing 3 isoform b
alt prot [1036aa] NLR family, pyrin domain containing 3 isoform a
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             4.4         43           2
 C cysteine            4.0         39           2
 D aspartate           5.1         50           2
 E glutamate           8.2         80           6
 F phenylalanine       4.5         44           2
 G glycine             5.2         51           2
 H histidine           2.9         28           1
 I isoleucine          4.3         42           1
 K lysine              6.7         66           2
 L leucine            14.5        142           2
 M methionine          2.8         27           2
 N asparagine          3.4         33           2
 P proline             3.3         32           2
 Q glutamine           4.4         43           2
 R arginine            5.3         52           2
 S serine              8.1         79           3
 T threonine           4.0         39           3
 V valine              5.0         49           2
 W tryptophan          1.4         14           1
 Y tyrosine            2.7         26           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   NLR family, pyrin domain containing 3 isoform c [Ho... 
NLRP3                 0.932   NLR family, pyrin domain containing 3 isoform d [Ho...
NLRP3                 0.911   NLR family, pyrin domain containing 3 isoform a [Ho...
NLRP3                 0.911   NLR family, pyrin domain containing 3 isoform a [Hom...
NLRP3                 0.907   NLR family, pyrin domain containing 3 isoform b [Hom...
NLRP12                0.428   NLR family, pyrin domain containing 12 isoform 2 [Ho...
NLRP14                0.277   NLR family, pyrin domain containing 14 
NLRP4                 0.233   NLR family, pyrin domain containing 4 
NLRP1                 0.223   NLR family, pyrin domain containing 1 isoform 2 [Homo...
NLRP1                 0.223   NLR family, pyrin domain containing 1 isoform 5 [Hom...
NLRP1                 0.223   NLR family, pyrin domain containing 1 isoform 1 [Hom...
NLRP9                 0.222   NLR family, pyrin domain containing 9 
NLRP1                 0.222   NLR family, pyrin domain containing 1 isoform 4 [Hom...
NLRP1                 0.222   NLR family, pyrin domain containing 1 isoform 3 [Hom...
NLRP2                 0.218   NLR family, pyrin domain containing 2 
NLRP13                0.214   NACHT, leucine rich repeat and PYD containing 13 [H...
NLRP5                 0.198   NACHT, LRR and PYD containing protein 5 
NLRP7                 0.195   NACHT, leucine rich repeat and PYD containing 7 isof...
NLRP7                 0.193   NACHT, leucine rich repeat and PYD containing 7 isof...
NLRP6                 0.193   NLR family, pyrin domain containing 6 
NLRP8                 0.192   NLR family, pyrin domain containing 8 
NLRP7                 0.187   NACHT, leucine rich repeat and PYD containing 7 iso...
NLRP10                0.168   NLR family, pyrin domain containing 10 
NLRP11                0.155   NLR family, pyrin domain containing 11 
NLRP12                0.098   NLR family, pyrin domain containing 12 isoform 1 [Ho...
RNH1                  0.089   ribonuclease/angiogenin inhibitor 
RNH1                  0.089   ribonuclease/angiogenin inhibitor 
RNH1                  0.089   ribonuclease/angiogenin inhibitor 
RNH1                  0.089   ribonuclease/angiogenin inhibitor 
RNH1                  0.089   ribonuclease/angiogenin inhibitor 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
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