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Search of human proteins with 14719418
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|14719418 tripartite motif protein TRIM5 isoform alpha [Homo
sapiens]
(493 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|14719418 tripartite motif protein TRIM5 isoform alpha [Homo s... 1016 0.0
gi|15011946 tripartite motif protein TRIM5 isoform delta [Homo s... 600 e-172
gi|15011944 tripartite motif protein TRIM5 isoform gamma [Homo s... 600 e-172
gi|51477687 tripartite motif protein 34 isoform 1 [Homo sapiens] 536 e-152
gi|18087807 tripartite motif protein 34 isoform 1 [Homo sapiens] 536 e-152
gi|51477690 tripartite motif-containing 6 and tripartite motif-c... 536 e-152
gi|18079262 tripartite motif-containing 6 isoform 2 [Homo sapiens] 531 e-151
gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens] 531 e-151
gi|117938316 tripartite motif-containing 22 [Homo sapiens] 521 e-148
gi|15208660 tripartite motif protein 21 [Homo sapiens] 348 5e-96
gi|145275183 tripartite motif protein 34 isoform 3 [Homo sapiens] 322 6e-88
gi|37622899 ring finger protein 137 [Homo sapiens] 292 4e-79
gi|112421127 tripartite motif-containing 58 [Homo sapiens] 281 7e-76
gi|21630277 tripartite motif-containing 11 [Homo sapiens] 262 5e-70
gi|5454014 tripartite motif-containing 38 [Homo sapiens] 256 4e-68
gi|5730009 ret finger protein [Homo sapiens] 244 1e-64
gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens] 238 9e-63
gi|18641343 tripartite motif protein 34 isoform 2 [Homo sapiens] 234 2e-61
gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens] 228 7e-60
gi|22749269 ring finger protein 129 [Homo sapiens] 225 8e-59
gi|68160933 tripartite motif-containing 17 isoform 1 [Homo sapiens] 221 1e-57
gi|7705825 tripartite motif-containing 17 isoform 1 [Homo sapiens] 221 1e-57
gi|68160935 tripartite motif-containing 17 isoform 2 [Homo sapiens] 201 2e-51
gi|15011941 tripartite motif protein TRIM4 isoform beta [Homo sa... 196 3e-50
gi|31542779 tripartite motif family-like 1 [Homo sapiens] 187 2e-47
gi|14670266 tripartite motif protein TRIM4 isoform alpha [Homo s... 184 2e-46
gi|209862805 SPRY domain containing 5 [Homo sapiens] 184 2e-46
gi|169202375 PREDICTED: tripartite motif-containing protein 64B-... 184 2e-46
gi|210147600 tripartite motif-containing 64 [Homo sapiens] 183 3e-46
gi|89034675 PREDICTED: similar to hCG1802386 [Homo sapiens] 182 6e-46
>gi|14719418 tripartite motif protein TRIM5 isoform alpha [Homo
sapiens]
Length = 493
Score = 1016 bits (2627), Expect = 0.0
Identities = 493/493 (100%), Positives = 493/493 (100%)
Query: 1 MASGILVNVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGESSCPVCRI 60
MASGILVNVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGESSCPVCRI
Sbjct: 1 MASGILVNVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGESSCPVCRI 60
Query: 61 SYQPENIRPNRHVANLVEKLREVKLSPEGQKVDHCARHGEKLLLFCQEDGKVICWLCERS 120
SYQPENIRPNRHVANLVEKLREVKLSPEGQKVDHCARHGEKLLLFCQEDGKVICWLCERS
Sbjct: 61 SYQPENIRPNRHVANLVEKLREVKLSPEGQKVDHCARHGEKLLLFCQEDGKVICWLCERS 120
Query: 121 QEHRGHHTFPTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDKTN 180
QEHRGHHTFPTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDKTN
Sbjct: 121 QEHRGHHTFPTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDKTN 180
Query: 181 VLADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHRLQ 240
VLADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHRLQ
Sbjct: 181 VLADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHRLQ 240
Query: 241 GSVMELLQGVDGVIKRTENVTLKKPETFPKNQRRVFRAPDLKGMLEVFRELTDVRRYWVD 300
GSVMELLQGVDGVIKRTENVTLKKPETFPKNQRRVFRAPDLKGMLEVFRELTDVRRYWVD
Sbjct: 241 GSVMELLQGVDGVIKRTENVTLKKPETFPKNQRRVFRAPDLKGMLEVFRELTDVRRYWVD 300
Query: 301 VTVAPNNISCAVISEDKRQVSSPKPQIIYGARGTRYQTFVNFNYCTGILGSQSITSGKHY 360
VTVAPNNISCAVISEDKRQVSSPKPQIIYGARGTRYQTFVNFNYCTGILGSQSITSGKHY
Sbjct: 301 VTVAPNNISCAVISEDKRQVSSPKPQIIYGARGTRYQTFVNFNYCTGILGSQSITSGKHY 360
Query: 361 WEVDVSKKTAWILGVCAGFQPDAMCNIEKNENYQPKYGYWVIGLEEGVKCSAFQDSSFHT 420
WEVDVSKKTAWILGVCAGFQPDAMCNIEKNENYQPKYGYWVIGLEEGVKCSAFQDSSFHT
Sbjct: 361 WEVDVSKKTAWILGVCAGFQPDAMCNIEKNENYQPKYGYWVIGLEEGVKCSAFQDSSFHT 420
Query: 421 PSVPFIVPLSVIICPDRVGVFLDYEACTVSFFNITNHGFLIYKFSHCSFSQPVFPYLNPR 480
PSVPFIVPLSVIICPDRVGVFLDYEACTVSFFNITNHGFLIYKFSHCSFSQPVFPYLNPR
Sbjct: 421 PSVPFIVPLSVIICPDRVGVFLDYEACTVSFFNITNHGFLIYKFSHCSFSQPVFPYLNPR 480
Query: 481 KCGVPMTLCSPSS 493
KCGVPMTLCSPSS
Sbjct: 481 KCGVPMTLCSPSS 493
>gi|15011946 tripartite motif protein TRIM5 isoform delta [Homo
sapiens]
Length = 326
Score = 600 bits (1548), Expect = e-172
Identities = 296/298 (99%), Positives = 297/298 (99%)
Query: 1 MASGILVNVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGESSCPVCRI 60
MASGILVNVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGESSCPVCRI
Sbjct: 1 MASGILVNVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGESSCPVCRI 60
Query: 61 SYQPENIRPNRHVANLVEKLREVKLSPEGQKVDHCARHGEKLLLFCQEDGKVICWLCERS 120
SYQPENIRPNRHVAN+VEKLREVKLSPEGQKVDHCARHGEKLLLFCQEDGKVICWLCERS
Sbjct: 61 SYQPENIRPNRHVANIVEKLREVKLSPEGQKVDHCARHGEKLLLFCQEDGKVICWLCERS 120
Query: 121 QEHRGHHTFPTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDKTN 180
QEHRGHHTF TEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDKTN
Sbjct: 121 QEHRGHHTFLTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDKTN 180
Query: 181 VLADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHRLQ 240
VLADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHRLQ
Sbjct: 181 VLADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHRLQ 240
Query: 241 GSVMELLQGVDGVIKRTENVTLKKPETFPKNQRRVFRAPDLKGMLEVFRELTDVRRYW 298
GSVMELLQGVDGVIKRTENVTLKKPETFPKNQRRVFRAPDLKGMLEVFRELTDVRRYW
Sbjct: 241 GSVMELLQGVDGVIKRTENVTLKKPETFPKNQRRVFRAPDLKGMLEVFRELTDVRRYW 298
>gi|15011944 tripartite motif protein TRIM5 isoform gamma [Homo
sapiens]
Length = 347
Score = 600 bits (1548), Expect = e-172
Identities = 296/298 (99%), Positives = 297/298 (99%)
Query: 1 MASGILVNVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGESSCPVCRI 60
MASGILVNVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGESSCPVCRI
Sbjct: 1 MASGILVNVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGESSCPVCRI 60
Query: 61 SYQPENIRPNRHVANLVEKLREVKLSPEGQKVDHCARHGEKLLLFCQEDGKVICWLCERS 120
SYQPENIRPNRHVAN+VEKLREVKLSPEGQKVDHCARHGEKLLLFCQEDGKVICWLCERS
Sbjct: 61 SYQPENIRPNRHVANIVEKLREVKLSPEGQKVDHCARHGEKLLLFCQEDGKVICWLCERS 120
Query: 121 QEHRGHHTFPTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDKTN 180
QEHRGHHTF TEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDKTN
Sbjct: 121 QEHRGHHTFLTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDKTN 180
Query: 181 VLADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHRLQ 240
VLADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHRLQ
Sbjct: 181 VLADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHRLQ 240
Query: 241 GSVMELLQGVDGVIKRTENVTLKKPETFPKNQRRVFRAPDLKGMLEVFRELTDVRRYW 298
GSVMELLQGVDGVIKRTENVTLKKPETFPKNQRRVFRAPDLKGMLEVFRELTDVRRYW
Sbjct: 241 GSVMELLQGVDGVIKRTENVTLKKPETFPKNQRRVFRAPDLKGMLEVFRELTDVRRYW 298
>gi|51477687 tripartite motif protein 34 isoform 1 [Homo sapiens]
Length = 488
Score = 536 bits (1382), Expect = e-152
Identities = 285/504 (56%), Positives = 359/504 (71%), Gaps = 27/504 (5%)
Query: 1 MASGILVNVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKG-ESSCPVCR 59
MAS IL+NV+EEVTCPICLELLT+PLSLDCGHS C+AC+T ++K+++ G +SSCPVC
Sbjct: 1 MASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCG 60
Query: 60 ISYQPENIRPNRHVANLVEKLREVKLSPE-GQKVDHCARHGEKLLLFCQEDGKVICWLCE 118
ISY E+++ N+H+AN+VE+L+EVKLSP+ G+K D C HGEKLLLFC+ED KVICWLCE
Sbjct: 61 ISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCE 120
Query: 119 RSQEHRGHHTFPTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDK 178
RSQEHRGHHT TEEV +E Q KLQA L+ L+++++EAE+LEADIREEK SWK Q+Q ++
Sbjct: 121 RSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTER 180
Query: 179 TNVLADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHR 238
+ +F+QLR IL+ EE ELQ LE+EE+ L +E E+VQQ Q +RELISD+E R
Sbjct: 181 QRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECR 240
Query: 239 LQGSVMELLQGVDGVIKRTENVTLKKPETFPKNQRRVFRAPDLKGMLEVFRELTDVRRYW 298
Q S MELLQ + G++K +E LKKP+ K + VF APDL ML++FRELT VR YW
Sbjct: 241 SQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYW 300
Query: 299 VDVTVAPNNISC-AVISEDKRQVSSPKPQIIYGARGTRYQTFVNFNYCTGILGSQSITSG 357
VDVT+ N++ V+SED+RQV S F +NY G+LGSQ +SG
Sbjct: 301 VDVTLNSVNLNLNLVLSEDQRQVIS-----------VPIWPFQCYNY--GVLGSQYFSSG 347
Query: 358 KHYWEVDVSKKTAWILGV-CAGFQPDAMCNIEKNEN-------YQPKYGYWVIGLEEGVK 409
KHYWEVDVSKKTAWILGV C + + + N Y+P +GYWVIGL+ K
Sbjct: 348 KHYWEVDVSKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCK 407
Query: 410 CSAFQDSSFHTPSVPFIVPLSVIICPDRVGVFLDYEACTVSFFNITNHGFLIYKFSHCSF 469
F++S S P ++ LS+ + P RVGVFLDYEA VSFFN+T+HG LIYKFS C F
Sbjct: 408 YGVFEES---LSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCF 464
Query: 470 SQPVFPYLNPRKCGVPMTLCSPSS 493
SQPV+PY NP C PMTLC PSS
Sbjct: 465 SQPVYPYFNPWNCPAPMTLCPPSS 488
>gi|18087807 tripartite motif protein 34 isoform 1 [Homo sapiens]
Length = 488
Score = 536 bits (1382), Expect = e-152
Identities = 285/504 (56%), Positives = 359/504 (71%), Gaps = 27/504 (5%)
Query: 1 MASGILVNVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKG-ESSCPVCR 59
MAS IL+NV+EEVTCPICLELLT+PLSLDCGHS C+AC+T ++K+++ G +SSCPVC
Sbjct: 1 MASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCG 60
Query: 60 ISYQPENIRPNRHVANLVEKLREVKLSPE-GQKVDHCARHGEKLLLFCQEDGKVICWLCE 118
ISY E+++ N+H+AN+VE+L+EVKLSP+ G+K D C HGEKLLLFC+ED KVICWLCE
Sbjct: 61 ISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCE 120
Query: 119 RSQEHRGHHTFPTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDK 178
RSQEHRGHHT TEEV +E Q KLQA L+ L+++++EAE+LEADIREEK SWK Q+Q ++
Sbjct: 121 RSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTER 180
Query: 179 TNVLADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHR 238
+ +F+QLR IL+ EE ELQ LE+EE+ L +E E+VQQ Q +RELISD+E R
Sbjct: 181 QRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECR 240
Query: 239 LQGSVMELLQGVDGVIKRTENVTLKKPETFPKNQRRVFRAPDLKGMLEVFRELTDVRRYW 298
Q S MELLQ + G++K +E LKKP+ K + VF APDL ML++FRELT VR YW
Sbjct: 241 SQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYW 300
Query: 299 VDVTVAPNNISC-AVISEDKRQVSSPKPQIIYGARGTRYQTFVNFNYCTGILGSQSITSG 357
VDVT+ N++ V+SED+RQV S F +NY G+LGSQ +SG
Sbjct: 301 VDVTLNSVNLNLNLVLSEDQRQVIS-----------VPIWPFQCYNY--GVLGSQYFSSG 347
Query: 358 KHYWEVDVSKKTAWILGV-CAGFQPDAMCNIEKNEN-------YQPKYGYWVIGLEEGVK 409
KHYWEVDVSKKTAWILGV C + + + N Y+P +GYWVIGL+ K
Sbjct: 348 KHYWEVDVSKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCK 407
Query: 410 CSAFQDSSFHTPSVPFIVPLSVIICPDRVGVFLDYEACTVSFFNITNHGFLIYKFSHCSF 469
F++S S P ++ LS+ + P RVGVFLDYEA VSFFN+T+HG LIYKFS C F
Sbjct: 408 YGVFEES---LSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCF 464
Query: 470 SQPVFPYLNPRKCGVPMTLCSPSS 493
SQPV+PY NP C PMTLC PSS
Sbjct: 465 SQPVYPYFNPWNCPAPMTLCPPSS 488
>gi|51477690 tripartite motif-containing 6 and tripartite
motif-containing 34 [Homo sapiens]
Length = 842
Score = 536 bits (1382), Expect = e-152
Identities = 285/504 (56%), Positives = 359/504 (71%), Gaps = 27/504 (5%)
Query: 1 MASGILVNVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKG-ESSCPVCR 59
MAS IL+NV+EEVTCPICLELLT+PLSLDCGHS C+AC+T ++K+++ G +SSCPVC
Sbjct: 355 MASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCG 414
Query: 60 ISYQPENIRPNRHVANLVEKLREVKLSPE-GQKVDHCARHGEKLLLFCQEDGKVICWLCE 118
ISY E+++ N+H+AN+VE+L+EVKLSP+ G+K D C HGEKLLLFC+ED KVICWLCE
Sbjct: 415 ISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCE 474
Query: 119 RSQEHRGHHTFPTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDK 178
RSQEHRGHHT TEEV +E Q KLQA L+ L+++++EAE+LEADIREEK SWK Q+Q ++
Sbjct: 475 RSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTER 534
Query: 179 TNVLADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHR 238
+ +F+QLR IL+ EE ELQ LE+EE+ L +E E+VQQ Q +RELISD+E R
Sbjct: 535 QRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECR 594
Query: 239 LQGSVMELLQGVDGVIKRTENVTLKKPETFPKNQRRVFRAPDLKGMLEVFRELTDVRRYW 298
Q S MELLQ + G++K +E LKKP+ K + VF APDL ML++FRELT VR YW
Sbjct: 595 SQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYW 654
Query: 299 VDVTVAPNNISC-AVISEDKRQVSSPKPQIIYGARGTRYQTFVNFNYCTGILGSQSITSG 357
VDVT+ N++ V+SED+RQV S F +NY G+LGSQ +SG
Sbjct: 655 VDVTLNSVNLNLNLVLSEDQRQVIS-----------VPIWPFQCYNY--GVLGSQYFSSG 701
Query: 358 KHYWEVDVSKKTAWILGV-CAGFQPDAMCNIEKNEN-------YQPKYGYWVIGLEEGVK 409
KHYWEVDVSKKTAWILGV C + + + N Y+P +GYWVIGL+ K
Sbjct: 702 KHYWEVDVSKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCK 761
Query: 410 CSAFQDSSFHTPSVPFIVPLSVIICPDRVGVFLDYEACTVSFFNITNHGFLIYKFSHCSF 469
F++S S P ++ LS+ + P RVGVFLDYEA VSFFN+T+HG LIYKFS C F
Sbjct: 762 YGVFEES---LSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCF 818
Query: 470 SQPVFPYLNPRKCGVPMTLCSPSS 493
SQPV+PY NP C PMTLC PSS
Sbjct: 819 SQPVYPYFNPWNCPAPMTLCPPSS 842
Score = 380 bits (975), Expect = e-105
Identities = 188/300 (62%), Positives = 232/300 (77%), Gaps = 2/300 (0%)
Query: 1 MASGILVNVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSML-DKGESSCPVCR 59
M S +LV+++EEVTCPICLELLT+PLS+DCGHSFCQAC+T N ++S++ +GE SCPVC+
Sbjct: 29 MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQ 88
Query: 60 ISYQPENIRPNRHVANLVEKLREVKLSPEGQ-KVDHCARHGEKLLLFCQEDGKVICWLCE 118
SYQP N+RPNRH+AN+V +LREV L P Q K CA HGEKL LFCQEDGKVICWLCE
Sbjct: 89 TSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCE 148
Query: 119 RSQEHRGHHTFPTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDK 178
RSQEHRGHHTF EEVAQEYQ K Q +L+ L+ ++QEAE+L A IRE+K SWK Q++ ++
Sbjct: 149 RSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPER 208
Query: 179 TNVLADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHR 238
+ +F QLR+ILD E EL+ LE+EE+ L+ + +E ++V QTQSLRELISDLE R
Sbjct: 209 CRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERR 268
Query: 239 LQGSVMELLQGVDGVIKRTENVTLKKPETFPKNQRRVFRAPDLKGMLEVFRELTDVRRYW 298
QGS MELLQ V V +R+E TL+KPE P R +FRAPDLK ML V RELTDV+ YW
Sbjct: 269 CQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYW 328
>gi|18079262 tripartite motif-containing 6 isoform 2 [Homo sapiens]
Length = 488
Score = 531 bits (1367), Expect = e-151
Identities = 283/503 (56%), Positives = 355/503 (70%), Gaps = 25/503 (4%)
Query: 1 MASGILVNVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSML-DKGESSCPVCR 59
M S +LV+++EEVTCPICLELLT+PLS+DCGHSFCQAC+T N ++S++ +GE SCPVC+
Sbjct: 1 MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQ 60
Query: 60 ISYQPENIRPNRHVANLVEKLREVKLSPEGQ-KVDHCARHGEKLLLFCQEDGKVICWLCE 118
SYQP N+RPNRH+AN+V +LREV L P Q K CA HGEKL LFCQEDGKVICWLCE
Sbjct: 61 TSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCE 120
Query: 119 RSQEHRGHHTFPTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDK 178
RSQEHRGHHTF EEVAQEYQ K Q +L+ L+ ++QEAE+L A IRE+K SWK Q++ ++
Sbjct: 121 RSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPER 180
Query: 179 TNVLADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHR 238
+ +F QLR+ILD E EL+ LE+EE+ L+ + +E ++V QTQSLRELISDLE R
Sbjct: 181 CRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERR 240
Query: 239 LQGSVMELLQGVDGVIKRTENVTLKKPETFPKNQRRVFRAPDLKGMLEVFRELTDVRRYW 298
QGS MELLQ V V +R+E TL+KPE P R +FRAPDLK ML V RELTDV+ YW
Sbjct: 241 CQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYW 300
Query: 299 VDVTVAPNNISC-AVISEDKRQVSSPKPQIIYGARGTRYQTFVNFNYCTGILGSQSITSG 357
VDVT+ P+ + V+++++RQV GA+ + + +Y +LGSQ +SG
Sbjct: 301 VDVTLNPHTANLNLVLAKNRRQVR------FVGAK-VSGPSCLEKHYDCSVLGSQHFSSG 353
Query: 358 KHYWEVDVSKKTAWILGVCA-------GFQPDAMCNIEKNENYQPKYGYWVIGLEEGVKC 410
KHYWEVDV+KKTAWILGVC+ F A N YQP+ GYWVIGL+ +
Sbjct: 354 KHYWEVDVAKKTAWILGVCSNSLGPTFSFNHFAQ-NHSAYSRYQPQSGYWVIGLQHNHEY 412
Query: 411 SAFQDSSFHTPSVPFIVPLSVIICPDRVGVFLDYEACTVSFFNITNHGFLIYKFSHCSFS 470
A++DSS PS + LS+ + P RVGVFLDYEA TVSF+N+TNHGF IY FS F
Sbjct: 413 RAYEDSS---PS----LLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFP 465
Query: 471 QPVFPYLNPRKCGVPMTLCSPSS 493
+ PY NP C +PMTL PSS
Sbjct: 466 TTLCPYFNPCNCVIPMTLRRPSS 488
>gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens]
Length = 516
Score = 531 bits (1367), Expect = e-151
Identities = 283/503 (56%), Positives = 355/503 (70%), Gaps = 25/503 (4%)
Query: 1 MASGILVNVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSML-DKGESSCPVCR 59
M S +LV+++EEVTCPICLELLT+PLS+DCGHSFCQAC+T N ++S++ +GE SCPVC+
Sbjct: 29 MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQ 88
Query: 60 ISYQPENIRPNRHVANLVEKLREVKLSPEGQ-KVDHCARHGEKLLLFCQEDGKVICWLCE 118
SYQP N+RPNRH+AN+V +LREV L P Q K CA HGEKL LFCQEDGKVICWLCE
Sbjct: 89 TSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCE 148
Query: 119 RSQEHRGHHTFPTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDK 178
RSQEHRGHHTF EEVAQEYQ K Q +L+ L+ ++QEAE+L A IRE+K SWK Q++ ++
Sbjct: 149 RSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPER 208
Query: 179 TNVLADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHR 238
+ +F QLR+ILD E EL+ LE+EE+ L+ + +E ++V QTQSLRELISDLE R
Sbjct: 209 CRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERR 268
Query: 239 LQGSVMELLQGVDGVIKRTENVTLKKPETFPKNQRRVFRAPDLKGMLEVFRELTDVRRYW 298
QGS MELLQ V V +R+E TL+KPE P R +FRAPDLK ML V RELTDV+ YW
Sbjct: 269 CQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYW 328
Query: 299 VDVTVAPNNISC-AVISEDKRQVSSPKPQIIYGARGTRYQTFVNFNYCTGILGSQSITSG 357
VDVT+ P+ + V+++++RQV GA+ + + +Y +LGSQ +SG
Sbjct: 329 VDVTLNPHTANLNLVLAKNRRQVR------FVGAK-VSGPSCLEKHYDCSVLGSQHFSSG 381
Query: 358 KHYWEVDVSKKTAWILGVCA-------GFQPDAMCNIEKNENYQPKYGYWVIGLEEGVKC 410
KHYWEVDV+KKTAWILGVC+ F A N YQP+ GYWVIGL+ +
Sbjct: 382 KHYWEVDVAKKTAWILGVCSNSLGPTFSFNHFAQ-NHSAYSRYQPQSGYWVIGLQHNHEY 440
Query: 411 SAFQDSSFHTPSVPFIVPLSVIICPDRVGVFLDYEACTVSFFNITNHGFLIYKFSHCSFS 470
A++DSS PS + LS+ + P RVGVFLDYEA TVSF+N+TNHGF IY FS F
Sbjct: 441 RAYEDSS---PS----LLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFP 493
Query: 471 QPVFPYLNPRKCGVPMTLCSPSS 493
+ PY NP C +PMTL PSS
Sbjct: 494 TTLCPYFNPCNCVIPMTLRRPSS 516
>gi|117938316 tripartite motif-containing 22 [Homo sapiens]
Length = 498
Score = 521 bits (1343), Expect = e-148
Identities = 273/512 (53%), Positives = 355/512 (69%), Gaps = 33/512 (6%)
Query: 1 MASGILVNVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSML-DKGESSCPVCR 59
M + V++++EVTCPICLELLT+PLSLDCGHSFCQAC+TA K+S++ +GESSCPVC+
Sbjct: 1 MDFSVKVDIEKEVTCPICLELLTEPLSLDCGHSFCQACITAKIKESVIISRGESSCPVCQ 60
Query: 60 ISYQPENIRPNRHVANLVEKLREVKLSP-EGQKVDHCARHGEKLLLFCQEDGKVICWLCE 118
+QP N+RPNRH+AN+VE+++EVK+SP EGQK D C HG+KL +FC+EDGKVICW+CE
Sbjct: 61 TRFQPGNLRPNRHLANIVERVKEVKMSPQEGQKRDVCEHHGKKLQIFCKEDGKVICWVCE 120
Query: 119 RSQEHRGHHTFPTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDK 178
SQEH+GH TF EV +E Q KLQ AL+ L ++ QEAE+LE DIR+E+ +WK IQ ++
Sbjct: 121 LSQEHQGHQTFRINEVVKECQEKLQVALQRLIKEDQEAEKLEDDIRQERTAWKNYIQIER 180
Query: 179 TNVLADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHR 238
+L F ++R ILD EE ELQ LE+ E ++L +L + ++VQQ Q LISDL+ R
Sbjct: 181 QKILKGFNEMRVILDNEEQRELQKLEEGEVNVLDNLAAATDQLVQQRQDASTLISDLQRR 240
Query: 239 LQGSVMELLQGVDGVIKRTENVTLKKPETFPKNQRRVFRAPDLKGMLEVFRELTDVRRYW 298
L+GS +E+LQ V V+KR+E+ TLKKP++ K + VFR PDL GML+V +ELTDV+ YW
Sbjct: 241 LRGSSVEMLQDVIDVMKRSESWTLKKPKSVSKKLKSVFRVPDLSGMLQVLKELTDVQYYW 300
Query: 299 VDVTVAPNNISCAV-ISEDKRQVSSPKPQIIYGARGTRYQTFVNFNYCT----GILGSQS 353
VDV + P + + V IS D+RQV + R TF N N C G+ G Q
Sbjct: 301 VDVMLNPGSATSNVAISVDQRQVKT-----------VRTCTFKNSNPCDFSAFGVFGCQY 349
Query: 354 ITSGKHYWEVDVSKKTAWILGV-----------CAGFQPDAMCNIEK-NENYQPKYGYWV 401
+SGK+YWEVDVS K AWILGV +GF D N K Y+P+YGYWV
Sbjct: 350 FSSGKYYWEVDVSGKIAWILGVHSKISSLNKRKSSGFAFDPSVNYSKVYSRYRPQYGYWV 409
Query: 402 IGLEEGVKCSAFQDSSFHTPSVPFIVPLSVIICPDRVGVFLDYEACTVSFFNITNHGFLI 461
IGL+ + +AF+DSS S P ++ L + + P R+GVFLDYEA VSFFN+TNHG LI
Sbjct: 410 IGLQNTCEYNAFEDSS---SSDPKVLTLFMAVPPCRIGVFLDYEAGIVSFFNVTNHGALI 466
Query: 462 YKFSHCSFSQPVFPYLNPRKCGVPMTLCSPSS 493
YKFS C FS+P +PY NP C VPMT+C PSS
Sbjct: 467 YKFSGCRFSRPAYPYFNPWNCLVPMTVCPPSS 498
>gi|15208660 tripartite motif protein 21 [Homo sapiens]
Length = 475
Score = 348 bits (894), Expect = 5e-96
Identities = 199/488 (40%), Positives = 287/488 (58%), Gaps = 45/488 (9%)
Query: 11 EEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGESSCPVCRISYQPENIRPN 70
EEVTCPICL+ +P+S++CGHSFCQ C++ K G S CPVCR + +N+RPN
Sbjct: 12 EEVTCPICLDPFVEPVSIECGHSFCQECISQVGKG-----GGSVCPVCRQRFLLKNLRPN 66
Query: 71 RHVANLVEKLREVKLSP-EGQKVDHCARHGEKLLLFCQEDGKVICWLCERSQEHRGHHTF 129
R +AN+V L+E+ EG + + CA HGE+L LFC++DGK +CW+C +S++HR H
Sbjct: 67 RQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAMV 126
Query: 130 PTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDKTNVLADFEQLR 189
P EE AQEYQ KLQ AL LR+KQ+ AE+LE +I ++A WK ++ K+ + A+F Q +
Sbjct: 127 PLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQK 186
Query: 190 DILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHRLQGSVMELLQG 249
+ L EE +LQ LEK+E + L+ L E ++ QQ+Q+L+ELIS+L+ R S +ELLQ
Sbjct: 187 NFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSALELLQE 246
Query: 250 VDGVIKRTENVTLKKPETFPKNQRRVFRAPDLKGMLEVFRELTDVRRYWVDVTVAPNNIS 309
V V++R+E+ LK + R V P LK ML R V +T+ P+ +
Sbjct: 247 VIIVLERSESWNLKDLDITSPELRSVCHVPGLKKML---------RTCAVHITLDPDTAN 297
Query: 310 -CAVISEDKRQVSSPKPQIIYGARGTRYQTFVNFNYCTGILGSQSITSGKHYWEVDVSKK 368
++SED+RQV Q R+ ++ +LG+Q SGKHYWEVDV+ K
Sbjct: 298 PWLILSEDRRQVRLGDTQQSIPGNEERFDSY------PMVLGAQHFHSGKHYWEVDVTGK 351
Query: 369 TAWILGVCAGFQPDAMCNIEKNENY--QPKYGYWVIGLEEGVKCSAFQDSSFHTPSVPFI 426
AW LGVC ++ + ++ K G+W I L + + + P
Sbjct: 352 EAWDLGVCRD-------SVRRKGHFLLSSKSGFWTIWL--------WNKQKYEAGTYP-Q 395
Query: 427 VPLSVIICPDRVGVFLDYEACTVSFFNITNHGFLIYKFSHCSFSQPVFPYLNP-----RK 481
PL + + P +VG+FLDYEA VSF+NIT+HG LIY FS C+F+ P+ P+ +P K
Sbjct: 396 TPLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFFSPGFNDGGK 455
Query: 482 CGVPMTLC 489
P+TLC
Sbjct: 456 NTAPLTLC 463
>gi|145275183 tripartite motif protein 34 isoform 3 [Homo sapiens]
Length = 270
Score = 322 bits (824), Expect = 6e-88
Identities = 159/257 (61%), Positives = 205/257 (79%), Gaps = 2/257 (0%)
Query: 1 MASGILVNVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKG-ESSCPVCR 59
MAS IL+NV+EEVTCPICLELLT+PLSLDCGHS C+AC+T ++K+++ G +SSCPVC
Sbjct: 1 MASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCG 60
Query: 60 ISYQPENIRPNRHVANLVEKLREVKLSPE-GQKVDHCARHGEKLLLFCQEDGKVICWLCE 118
ISY E+++ N+H+AN+VE+L+EVKLSP+ G+K D C HGEKLLLFC+ED KVICWLCE
Sbjct: 61 ISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCE 120
Query: 119 RSQEHRGHHTFPTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDK 178
RSQEHRGHHT TEEV +E Q KLQA L+ L+++++EAE+LEADIREEK SWK Q+Q ++
Sbjct: 121 RSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTER 180
Query: 179 TNVLADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHR 238
+ +F+QLR IL+ EE ELQ LE+EE+ L +E E+VQQ Q +RELISD+E R
Sbjct: 181 QRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECR 240
Query: 239 LQGSVMELLQGVDGVIK 255
Q S MELLQ + G++K
Sbjct: 241 SQWSTMELLQDMSGIMK 257
>gi|37622899 ring finger protein 137 [Homo sapiens]
Length = 485
Score = 292 bits (748), Expect = 4e-79
Identities = 179/510 (35%), Positives = 284/510 (55%), Gaps = 67/510 (13%)
Query: 9 VKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGES-----SCPVCRISYQ 63
+ EEV CPIC+ L +P+S+DCGHSFC +CL+ + GES +CP+CR Q
Sbjct: 10 IVEEVACPICMTFLREPMSIDCGHSFCHSCLSGLWEIP----GESQNWGYTCPLCRAPVQ 65
Query: 64 PENIRPNRHVANLVEKLREVKLSPE-GQKVDHCARHGEKLLLFCQEDGKVICWLCERSQE 122
P N+RPN +AN+VEK+R ++L P G K D C RHGEKL +FC+ED ++C C +S E
Sbjct: 66 PRNLRPNWQLANVVEKVRLLRLHPGMGLKGDLCERHGEKLKMFCKEDVLIMCEACSQSPE 125
Query: 123 HRGHHTFPTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDKTNVL 182
H H P E+VA EY+ +L ALE L+++Q+EA +LE R+ A+WK Q++ K +++
Sbjct: 126 HEAHSVVPMEDVAWEYKWELHEALEHLKKEQEEAWKLEVGERKRTATWKIQVETRKQSIV 185
Query: 183 ADFEQLRDILD----------WEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELI 232
+FE+ + +L+ E + L +L++E + ++ L + +E++QQ+Q L +I
Sbjct: 186 WEFEKYQRLLEKKQPPHRQLGAEVAAALASLQREAAETMQKLELNHSELIQQSQVLWRMI 245
Query: 233 SDLEHRLQGSVMELLQGVDGVIKRTENVTLKKPETFPKNQRRVFRAPDLKGMLEVFRELT 292
++L+ R Q V +LQ + V+ R+++ +L++PE + R L+ +L
Sbjct: 246 AELKERSQRPVRWMLQDIQEVLNRSKSWSLQQPEPISLELKTDCRVLGLREIL------- 298
Query: 293 DVRRYWVDVTVAPNN-ISCAVISEDKRQVSSPKPQIIYGARGTRY----QTFVNFNYCTG 347
+ Y DV + P+ S ++SED+++V YG + + F +N
Sbjct: 299 --KTYAADVRLDPDTAYSRLIVSEDRKRVH-------YGDTNQKLPDNPERFYRYNI--- 346
Query: 348 ILGSQSITSGKHYWEVDVSKKTAWILGVCAGFQPDAMCNIEKNE--NYQPKYGYWVIGLE 405
+LGSQ I+SG+HYWEV+V ++ W LGVC N+++ E P YG+WVI L
Sbjct: 347 VLGSQCISSGRHYWEVEVGDRSEWGLGVCKQ-------NVDRKEVVYLSPHYGFWVIRLR 399
Query: 406 EGVKCSAFQDSSFHTPSVPFIVPLSVIICPDRVGVFLDYEACTVSFFNITNHGFLIYKFS 465
+G + A T P LS+ + P RVG+F+DYEA +SF+N+T+ G I+ F
Sbjct: 400 KGNEYRA------GTDEYPI---LSLPVPPRRVGIFVDYEAHDISFYNVTDCGSHIFTFP 450
Query: 466 HCSFSQPVFPYLNP-----RKCGVPMTLCS 490
F + PY +P P+ +CS
Sbjct: 451 RYPFPGRLLPYFSPCYSIGTNNTAPLAICS 480
>gi|112421127 tripartite motif-containing 58 [Homo sapiens]
Length = 486
Score = 281 bits (720), Expect = 7e-76
Identities = 169/471 (35%), Positives = 253/471 (53%), Gaps = 36/471 (7%)
Query: 9 VKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSM-LDKGESSCPVCRISYQPENI 67
++E+ CP+CL+ L +P+S+DCGHSFC C++ +KS G +CP CR ++P
Sbjct: 10 LREDARCPVCLDFLQEPVSVDCGHSFCLRCISEFCEKSDGAQGGVYACPQCRGPFRPSGF 69
Query: 68 RPNRHVANLVEKLREVKLSPEGQKVDHCARHGEKLLLFCQEDGKVICWLCERSQEHRGHH 127
RPNR +A LVE +R + L G CARHGE L FC+ED +CW+C+ EHR H
Sbjct: 70 RPNRQLAGLVESVRRLGLGA-GPGARRCARHGEDLSRFCEEDEAALCWVCDAGPEHRTHR 128
Query: 128 TFPTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDKTNVLADFEQ 187
T P +E A YQVKLQ ALE++R++ ++A EA++ ++ WK +++ + +FE+
Sbjct: 129 TAPLQEAAGSYQVKLQMALELMRKELEDALTQEANVGKKTVIWKEKVEMQRQRFRLEFEK 188
Query: 188 LRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHRLQGSVMELL 247
R L EE +L+ LE EE L+ L S++ +VQQ+++L+EL +L+ R Q + LL
Sbjct: 189 HRGFLAQEEQRQLRRLEAEERATLQRLRESKSRLVQQSKALKELADELQERCQRPALGLL 248
Query: 248 QGVDGVIKRTENVTLKKPETFPKNQRRVFRAPDLKGMLEVFRELTDVRRYWVDVTVAPNN 307
+GV GV+ R++ VT + E P + P + +L R++ VDV + P
Sbjct: 249 EGVRGVLSRSKAVTRLEAENIPMELKTACCIPGRRELL---------RKFQVDVKLDPAT 299
Query: 308 I-SCAVISEDKRQVSSPKPQIIYGARGTRYQTFVNFNYCTGILGSQSITSGKHYWEVDVS 366
+++ D R V +P R+ T+ ILG QS +SG+HYWEV V
Sbjct: 300 AHPSLLLTADLRSVQDGEPWRDVPNNPERFDTW------PCILGLQSFSSGRHYWEVLVG 353
Query: 367 KKTAWILGVCAGFQPDAMCNIEKNENY-QPKYGYWVIGLEEGVKCSAFQDSSFHTPSVPF 425
+ W LGVC P K E P+ G W + L +G + S
Sbjct: 354 EGAEWGLGVCQDTLP------RKGETTPSPENGVWALWLLKGNEYMVLASPS-------- 399
Query: 426 IVPLSVIICPDRVGVFLDYEACTVSFFNITNHGFLIYKFSHCSFSQPVFPY 476
VPL + P +G+FLDYEA +SF+N+T+ G IY F+ FS + PY
Sbjct: 400 -VPLLQLESPRCIGIFLDYEAGEISFYNVTD-GSYIYTFNQL-FSGLLRPY 447
>gi|21630277 tripartite motif-containing 11 [Homo sapiens]
Length = 468
Score = 262 bits (670), Expect = 5e-70
Identities = 169/497 (34%), Positives = 257/497 (51%), Gaps = 49/497 (9%)
Query: 2 ASGILVNVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGESSCPVCRIS 61
A + N++EE TC ICL+ T P+ DCGH+FC+ C+ + +G +CP CR
Sbjct: 3 APDLSTNLQEEATCAICLDYFTDPVMTDCGHNFCRECIRRCWGQP---EGPYACPECREL 59
Query: 62 YQPENIRPNRHVANLVEKLREVKL-SPEGQKVDHCARHGEKLLLFCQEDGKVICWLCERS 120
N+RPNR +A + E R + SP Q V C H E L FC ++ +++C CERS
Sbjct: 60 SPQRNLRPNRPLAKMAEMARRLHPPSPVPQGV--CPAHREPLAAFCGDELRLLCAACERS 117
Query: 121 QEHRGHHTFPTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDKTN 180
EH H P ++ A++ + KL+ +LE LR++ Q+A +A E W+ ++ + N
Sbjct: 118 GEHWAHRVRPLQDAAEDLKAKLEKSLEHLRKQMQDALLFQAQADETCVLWQKMVESQRQN 177
Query: 181 VLADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHRLQ 240
VL +FE+LR +L EE LQ LE+EE ++L L + QQ+ L ELI++LE R Q
Sbjct: 178 VLGEFERLRRLLAEEEQQLLQRLEEEELEVLPRLREGAAHLGQQSAHLAELIAELEGRCQ 237
Query: 241 GSVMELLQGVDGVIKRTENVTLKKPETFPKNQRRVFRAPDLKGMLEVFRELTDVRRYWVD 300
+ LLQ + ++R ++V L+ PE P R V R P G++E +RR+ D
Sbjct: 238 LPALGLLQDIKDALRRVQDVKLQPPEVVPMELRTVCRVP---GLVET------LRRFRGD 288
Query: 301 VTVAPNNISC-AVISEDKRQVSSPKPQIIYGARGTRYQTFVN----FNYCTGILGSQSIT 355
VT+ P+ + ++SED+R V RG Q + F+ +LG + T
Sbjct: 289 VTLDPDTANPELILSEDRRSVQ----------RGDLRQALPDSPERFDPGPCVLGQERFT 338
Query: 356 SGKHYWEVDVSKKTAWILGVCAGFQPDAMCNIEKNENYQPKYGYWVIGLEEGVKCSAFQD 415
SG+HYWEV+V +T+W LGVC N ++ G+W++
Sbjct: 339 SGRHYWEVEVGDRTSWALGVCR-----ENVNRKEKGELSAGNGFWILVFL---------- 383
Query: 416 SSFHTPSVPFIVPLSVIICPDRVGVFLDYEACTVSFFNITNHGFLIYKFSHCSFSQPVFP 475
S++ S + PL P RVG+FLDYEA +SF++ T+ G L++ F FS + P
Sbjct: 384 GSYYNSSERALAPLR--DPPRRVGIFLDYEAGHLSFYSATD-GSLLFIFPEIPFSGTLRP 440
Query: 476 YLNPRKCG-VPMTLCSP 491
+P PMT+C P
Sbjct: 441 LFSPLSSSPTPMTICRP 457
>gi|5454014 tripartite motif-containing 38 [Homo sapiens]
Length = 465
Score = 256 bits (653), Expect = 4e-68
Identities = 159/478 (33%), Positives = 243/478 (50%), Gaps = 52/478 (10%)
Query: 11 EEVTCPICLELLTQPLSLDCGHSFCQACLT---ANHKKSMLDKGESSCPVCRISYQPENI 67
EE TC ICL L+T P+S++CGHS+C C+T N + L + CP CR + +++
Sbjct: 12 EEATCSICLSLMTNPVSINCGHSYCHLCITDFFKNPSQKQLRQETFCCPQCRAPFHMDSL 71
Query: 68 RPNRHVANLVEKLREVKLSPEGQKVDHCARHGEKLLLFCQEDGKVICWLCERSQEHRGHH 127
RPN+ + +L+E L+E C HGE+ LFC+++G++ICW CER+ +H+GH
Sbjct: 72 RPNKQLGSLIEALKETDQEMS------CEEHGEQFHLFCEDEGQLICWRCERAPQHKGHT 125
Query: 128 TFPTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDKTNVLADFEQ 187
T E+V Q Y+ KLQ A+ L+Q + E + WK ++Q + + +DF+
Sbjct: 126 TALVEDVCQGYKEKLQKAVTKLKQLEDRCTEQKLSTAMRITKWKEKVQIQRQKIRSDFKN 185
Query: 188 LRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHRLQGSVMELL 247
L+ L EE + L LEKEE+ L L + E + ++ L+ I +LE + QGS +LL
Sbjct: 186 LQCFLHEEEKSYLWRLEKEEQQTLSRLRDYEAGLGLKSNELKSHILELEEKCQGSAQKLL 245
Query: 248 QGVDGVIKRTENVTLKKPETFPKNQRRVFRAPDLKGMLEVFRELTDV----RRYWVDVTV 303
Q V+ + R+ V L+ E + +L M V + DV R + V VT+
Sbjct: 246 QNVNDTLSRSWAVKLETSEAV---------SLELHTMCNVSKLYFDVKKMLRSHQVSVTL 296
Query: 304 APNNISC-AVISEDKRQVSSPKPQIIYGARGTRYQTFVNFNYCTGILGSQSITSGKHYWE 362
P+ ++SED+RQV+ Q R+ F +LG + TSG+ Y+E
Sbjct: 297 DPDTAHHELILSEDRRQVTRGYTQENQDTSSRRFTAF------PCVLGCEGFTSGRRYFE 350
Query: 363 VDVSKKTAWILGVCAGFQPDAMCNIEKNE--NYQPKYGYWVIGL--EEGVKCSAFQDSSF 418
VDV + T W LGVC M N+++ +P+ G+W + L ++G +S
Sbjct: 351 VDVGEGTGWDLGVC-------MENVQRGTGMKQEPQSGFWTLRLCKKKGYVALTSPPTSL 403
Query: 419 HTPSVPFIVPLSVIICPDRVGVFLDYEACTVSFFNITNHGFLIYKFSHCSFSQPVFPY 476
H P + VG+FLDYEA VSF+N N G I+ F SFS + PY
Sbjct: 404 HLHEQPLL-----------VGIFLDYEAGVVSFYN-GNTGCHIFTFPKASFSDTLRPY 449
>gi|5730009 ret finger protein [Homo sapiens]
Length = 513
Score = 244 bits (624), Expect = 1e-64
Identities = 163/517 (31%), Positives = 256/517 (49%), Gaps = 49/517 (9%)
Query: 1 MASGILVN-VKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGESSCPVCR 59
MASG + +++E TCP+CL+ +P+ LDCGH+ C ACL + + SCP CR
Sbjct: 1 MASGSVAECLQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWGTA---ETNVSCPQCR 57
Query: 60 ISYQPENIRPNRHVAN---LVEKLREVKLSPEGQKVDHCARHGEKLLLFCQEDGKVICWL 116
++ ++RPNRH+AN LV++LR + S G ++ C +H E L L+C+ED IC +
Sbjct: 58 ETFPQRHMRPNRHLANVTQLVKQLRTERPSGPGGEMGVCEKHREPLKLYCEEDQMPICVV 117
Query: 117 CERSQEHRGHHTFPTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQY 176
C+RS+EHRGH P EE + ++ ++Q L+ L++ + + A + +A + Q
Sbjct: 118 CDRSREHRGHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAELLSLTQM 177
Query: 177 DKTNVLADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLE 236
++ ++ +FEQL L E L LE+ + I S+ + T+ L LI+ LE
Sbjct: 178 EREKIVWEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIAQLE 237
Query: 237 HRLQGSVMELLQGVDGVIKRTENVTLKKPETFPKN---------QRRVFRAPDLKGM--- 284
+ Q ELLQ + + R E + + +P P + Q+ +F LK
Sbjct: 238 EKQQQPTRELLQDIGDTLSRAERIRIPEPWITPPDLQEKIHIFAQKCLFLTESLKQFTEK 297
Query: 285 ----LEVFRELTDVRRYWVDVTVAPNN-ISCAVISEDKRQVSSPKPQIIYGARGTRYQTF 339
+E +EL + + Y VDVT+ P+ ++S++ RQV Q R
Sbjct: 298 MQSDMEKIQELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDLPDNPER---- 353
Query: 340 VNFNYCTGILGSQSITSGKHYWEVDVSKKTAWILGVCAGFQPDAMCNIEKNENYQPKYGY 399
FN +LGS +G+HYWEV+V K W +GVC D++C + P+ G+
Sbjct: 354 --FNLFPCVLGSPCFIAGRHYWEVEVGDKAKWTIGVC----EDSVCR-KGGVTSAPQNGF 406
Query: 400 WVIGLEEGVKCSAFQDSSFHTPSVPFIVPLSVIICPDRVGVFLDYEACTVSFFNITNHGF 459
W + L G + A ++P PL RVG+FLDY+A VSF+N+T
Sbjct: 407 WAVSLWYGKEYWALTSP---MTALPLRTPL------QRVGIFLDYDAGEVSFYNVTERCH 457
Query: 460 LIYKFSHCSFSQPVFPYL----NPRKCGVPMTLCSPS 492
+ FSH +F PV PY + K P+ +C S
Sbjct: 458 -TFTFSHATFCGPVRPYFSLSYSGGKSAAPLIICPMS 493
>gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens]
Length = 488
Score = 238 bits (607), Expect = 9e-63
Identities = 159/505 (31%), Positives = 263/505 (52%), Gaps = 57/505 (11%)
Query: 6 LVNVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGESSCPVCRISYQPE 65
L N++ E +C +CLE L +P+ ++CGH+FC+AC+T + D CPVCR + +
Sbjct: 20 LENLQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWEDLERD---FPCPVCRKTSRYR 76
Query: 66 NIRPNRHVANLVE---KLREVKLSPEGQKVDHCARHGEKLLLFCQEDGKVICWLCERSQE 122
++RPNR + ++VE +L+ VK + + C +H E L LFC ED + +C +C S
Sbjct: 77 SLRPNRQLGSMVEIAKQLQAVKRKIRDESL--CPQHHEALSLFCYEDQEAVCLICAISHT 134
Query: 123 HRGHHTFPTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDKTNVL 182
HR H P ++ QEY+ KLQ LE L QK QE ++ ++ K ++ + +L
Sbjct: 135 HRAHTVVPLDDATQEYKEKLQKCLEPLEQKLQEITRCKSSEEKKPGELKRLVESRRQQIL 194
Query: 183 ADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHRLQGS 242
+FE+L LD E+ L LE+EE+DIL+ L + + + + L L +++E + S
Sbjct: 195 REFEELHRRLDEEQQVLLSRLEEEEQDILQRLRENAAHLGDKRRDLAHLAAEVEGKCLQS 254
Query: 243 VMELLQGVDGVIKRTE--------NVTLKKPETFPKNQRRVFRAPDLKGMLEVFRELTDV 294
E+L+ V +++ E +V+++ + F R+ F + ++ ++L
Sbjct: 255 GFEMLKDVKSTLEKCEKVKTMEVTSVSIELEKNFSNFPRQYF------ALRKILKQLI-- 306
Query: 295 RRYWVDVTVAPNNI-SCAVISEDKRQVSSPKPQIIYGARGTRYQTFVNFNYCTGILGSQS 353
DVT+ P V+SED++ V + ++ T F + +L ++
Sbjct: 307 ----ADVTLDPETAHPNLVLSEDRKSVKFVETRL-----RDLPDTPRRFTFYPCVLATEG 357
Query: 354 ITSGKHYWEVDVSKKTAWILGVCAGFQPDAMCNIEKNE-NYQPKYGYWVIGLEEGVKCSA 412
TSG+HYWEV+V KT W +GVC D++ K E P+ GYW + L G K +A
Sbjct: 358 FTSGRHYWEVEVGDKTHWAVGVCR----DSVS--RKGELTPLPETGYWRVRLWNGDKYAA 411
Query: 413 FQDSSFHTPSVPFIVPLSVIICPDRVGVFLDYEACTVSFFNITNHGFLIYKFSHCSFSQP 472
+ PF PL + + P RVG+FLDYEA T+SF+N+T+ IY F+ +F++
Sbjct: 412 --------TTTPF-TPLHIKVKPKRVGIFLDYEAGTLSFYNVTDRSH-IYTFTD-TFTEK 460
Query: 473 VFPYLNP-----RKCGVPMTLCSPS 492
++P P RK P+T+ P+
Sbjct: 461 LWPLFYPGIRAGRKNAAPLTIRPPT 485
>gi|18641343 tripartite motif protein 34 isoform 2 [Homo sapiens]
Length = 243
Score = 234 bits (596), Expect = 2e-61
Identities = 133/259 (51%), Positives = 164/259 (63%), Gaps = 25/259 (9%)
Query: 244 MELLQGVDGVIKRTENVTLKKPETFPKNQRRVFRAPDLKGMLEVFRELTDVRRYWVDVTV 303
MELLQ + G++K +E LKKP+ K + VF APDL ML++FRELT VR YWVDVT+
Sbjct: 1 MELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYWVDVTL 60
Query: 304 APNNISC-AVISEDKRQVSSPKPQIIYGARGTRYQTFVNFNYCTGILGSQSITSGKHYWE 362
N++ V+SED+RQV S F +NY G+LGSQ +SGKHYWE
Sbjct: 61 NSVNLNLNLVLSEDQRQVIS-----------VPIWPFQCYNY--GVLGSQYFSSGKHYWE 107
Query: 363 VDVSKKTAWILGV-CAGFQPDAMCNIEKNEN-------YQPKYGYWVIGLEEGVKCSAFQ 414
VDVSKKTAWILGV C + + + N Y+P +GYWVIGL+ K F+
Sbjct: 108 VDVSKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFE 167
Query: 415 DSSFHTPSVPFIVPLSVIICPDRVGVFLDYEACTVSFFNITNHGFLIYKFSHCSFSQPVF 474
+S S P ++ LS+ + P RVGVFLDYEA VSFFN+T+HG LIYKFS C FSQPV+
Sbjct: 168 ES---LSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVY 224
Query: 475 PYLNPRKCGVPMTLCSPSS 493
PY NP C PMTLC PSS
Sbjct: 225 PYFNPWNCPAPMTLCPPSS 243
>gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens]
Length = 518
Score = 228 bits (582), Expect = 7e-60
Identities = 158/523 (30%), Positives = 263/523 (50%), Gaps = 63/523 (12%)
Query: 6 LVNVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGESSCPVCRISYQPE 65
L N++ E +C +CLE L +P+ ++CGH+FC+AC+T + D CPVCR + +
Sbjct: 20 LENLQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWEDLERD---FPCPVCRKTSRYR 76
Query: 66 NIRPNRHVANLVE---KLREVKLSPEGQKVDHCARHGEKLLLFCQEDGKVICWLCERSQE 122
++RPNR + ++VE +L+ VK + + C +H E L LFC ED + +C +C S
Sbjct: 77 SLRPNRQLGSMVEIAKQLQAVKRKIRDESL--CPQHHEALSLFCYEDQEAVCLICAISHT 134
Query: 123 HRGHHTFPTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDKTNVL 182
HR H P ++ QEY+ KLQ LE L QK QE ++ ++ K ++ + +L
Sbjct: 135 HRAHTVVPLDDATQEYKEKLQKCLEPLEQKLQEITRCKSSEEKKPGELKRLVESRRQQIL 194
Query: 183 ADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHRLQGS 242
+FE+L LD E+ L LE+EE+DIL+ L + + + + L L +++E + S
Sbjct: 195 REFEELHRRLDEEQQVLLSRLEEEEQDILQRLRENAAHLGDKRRDLAHLAAEVEGKCLQS 254
Query: 243 VMELLQGVDGVIKRT---------ENVTLKKPETFPKNQRRVFRAPDLKGM------LEV 287
E+L+ V +++ + + + + + R +K M +E+
Sbjct: 255 GFEMLKDVKSTLEKNIPRKFGGSLSTICPRDHKALLGLVKEINRCEKVKTMEVTSVSIEL 314
Query: 288 FRELTDVRRYW-----------VDVTVAPNNISC-AVISEDKRQVSSPKPQIIYGARGTR 335
+ ++ R + DVT+ P V+SED++ V + ++
Sbjct: 315 EKNFSNFPRQYFALRKILKQLIADVTLDPETAHPNLVLSEDRKSVKFVETRL-----RDL 369
Query: 336 YQTFVNFNYCTGILGSQSITSGKHYWEVDVSKKTAWILGVCAGFQPDAMCNIEKNE-NYQ 394
T F + +L ++ TSG+HYWEV+V KT W +GVC D++ K E
Sbjct: 370 PDTPRRFTFYPCVLATEGFTSGRHYWEVEVGDKTHWAVGVCR----DSVS--RKGELTPL 423
Query: 395 PKYGYWVIGLEEGVKCSAFQDSSFHTPSVPFIVPLSVIICPDRVGVFLDYEACTVSFFNI 454
P+ GYW + L G K +A + PF PL + + P RVG+FLDYEA T+SF+N+
Sbjct: 424 PETGYWRVRLWNGDKYAA--------TTTPF-TPLHIKVKPKRVGIFLDYEAGTLSFYNV 474
Query: 455 TNHGFLIYKFSHCSFSQPVFPYLNP-----RKCGVPMTLCSPS 492
T+ IY F+ +F++ ++P P RK P+T+ P+
Sbjct: 475 TDRSH-IYTFTD-TFTEKLWPLFYPGIRAGRKNAAPLTIRPPT 515
>gi|22749269 ring finger protein 129 [Homo sapiens]
Length = 471
Score = 225 bits (573), Expect = 8e-59
Identities = 146/496 (29%), Positives = 250/496 (50%), Gaps = 44/496 (8%)
Query: 6 LVNVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGESSCPVCRISYQPE 65
LVN++EE +CPICLE L P++++CGH+FC++CL+ + K LD CPVCR + +
Sbjct: 7 LVNLQEESSCPICLEYLKDPVTINCGHNFCRSCLSVSWKD--LDD-TFPCPVCRFCFPYK 63
Query: 66 NIRPNRHVANLVEKLREVKLSPEGQKVDH----CARHGEKLLLFCQEDGKVICWLCERSQ 121
+ R N + NL E +++++ +K C +H + L LFC +D +++C C S
Sbjct: 64 SFRRNPQLRNLTEIAKQLQIRRSKRKRQKENAMCEKHNQFLTLFCVKDLEILCTQCSFST 123
Query: 122 EHRGHHTFPTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDKTNV 181
+H+ H+ P ++ A ++ L+ +LE LR + E++ + K +++Y + +
Sbjct: 124 KHQKHYICPIKKAASYHREILEGSLEPLRNNIERVEKVIILQGSKSVELKKKVEYKREEI 183
Query: 182 LADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHRLQG 241
++FEQ+R L E+ L+ ++ EE +IL L + E+ +L+ L+ ++E +
Sbjct: 184 NSEFEQIRLFLQNEQEMILRQIQDEEMNILAKLNENLVELSDYVSTLKHLLREVEGKSVQ 243
Query: 242 SVMELLQGVDGVIKRTENVTLKKPETFPKNQRRVFRAPDLKGMLEVFRELTDVRRYWVDV 301
S +ELL + + +N+ + +F + P G+ + ++ + VDV
Sbjct: 244 SNLELLTQAKSMHHKYQNLKCPELFSFRLTKYGFSLPPQYSGLDRI------IKPFQVDV 297
Query: 302 TVAPNNI-SCAVISEDKRQV--SSPKPQIIYGARGTRYQTFVNFNYCTGILGSQSITSGK 358
+ N ++SED++ V K I Y R F C +LGSQ +SG+
Sbjct: 298 ILDLNTAHPQLLVSEDRKAVRYERKKRNICYDPR--------RFYVCPAVLGSQRFSSGR 349
Query: 359 HYWEVDVSKKTAWILGVCAGFQPDAMCNIEKNENYQPKY--GYWVIGLEEGVKCSAFQDS 416
HYWEV+V K WILGVC + +N QP G+W IG
Sbjct: 350 HYWEVEVGNKPKWILGVCQDC-------LLRNWQDQPSVLGGFWAIGR---------YMK 393
Query: 417 SFHTPSVPFIVPLSVIICPDRVGVFLDYEACTVSFFNITNHGFLIYKFSHCSFSQPVFPY 476
S + S P L ++ P ++G+FLDYE +SF+N+ N ++Y F+ C F++ V+PY
Sbjct: 394 SGYVASGPKTTQLLPVVKPSKIGIFLDYELGDLSFYNM-NDRSILYTFNDC-FTEAVWPY 451
Query: 477 LNPRKCGVPMTLCSPS 492
P+ +CS S
Sbjct: 452 FYTGTDSEPLKICSVS 467
>gi|68160933 tripartite motif-containing 17 isoform 1 [Homo sapiens]
Length = 477
Score = 221 bits (563), Expect = 1e-57
Identities = 143/479 (29%), Positives = 237/479 (49%), Gaps = 44/479 (9%)
Query: 9 VKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGESS------CPVCRISY 62
++EE TC ICL+ T P+ CGH+FC+AC+ + +K+ KG CP CR
Sbjct: 10 LQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSWEKARGKKGRRKRKGSFPCPECREMS 69
Query: 63 QPENIRPNRHVANLVEKLREVKLSPEGQKVDHCARHGEKLLLFCQEDGKVICWLCERSQE 122
N+ PNR + + E ++ P QK D C H E L LFCQ+D IC +C S+E
Sbjct: 70 PQRNLLPNRLLTKVAEMAQQ---HPGLQKQDLCQEHHEPLKLFCQKDQSPICVVCRESRE 126
Query: 123 HRGHHTFPTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDKTNVL 182
HR H P EE Q Y++KL+ +E LR++ L+A + A W+ +++ + ++
Sbjct: 127 HRLHRVLPAEEAVQGYKLKLEEDMEYLREQITRTGNLQAREEQSLAEWQGKVKERRERIV 186
Query: 183 ADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHRLQGS 242
+FE++ L EE LQ LE EEE+ L S + +Q SL L+ LE R
Sbjct: 187 LEFEKMNLYLVEEEQRLLQALETEEEETASRLRESVACLDRQGHSLELLLLQLEERSTQG 246
Query: 243 VMELLQGVDGVIKRTENVTLKKPETFPKNQ-RRVFRAPDLKGMLEVFRELTDVRRYWVDV 301
+++LQ + + R NV+++ PE P + R V R P G +EV R + DV
Sbjct: 247 PLQMLQDMKEPLSRKNNVSVQCPEVAPPTRPRTVCRVP---GQIEVLRGFLE------DV 297
Query: 302 TVAPNNISCAVISEDKRQVSSPKPQIIYGARGTRYQTFVNFNYCTGILGSQSITSGKHYW 361
+ ++ + RQ + + G+ + + F +G + +SG+HYW
Sbjct: 298 VPDATSAYPYLLLYESRQ----RRYLGSSPEGSGFCSKDRFVAYPCAVGQTAFSSGRHYW 353
Query: 362 EV--DVSKKTAWILGVCAGFQPDAMCNIEKNENYQ--PKYGYWVIGLEEGVKCSAFQDSS 417
EV +++ W LGVC N+ + + P+ G+WV+ L +G K
Sbjct: 354 EVGMNITGDALWALGVCRD-------NVSRKDRVPKCPENGFWVVQLSKGTK-------- 398
Query: 418 FHTPSVPFIVPLSVIICPDRVGVFLDYEACTVSFFNITNHGFLIYKFSHCSFSQPVFPY 476
+ + + P+ ++ P +G+FLD+EA VSF+++++ G ++ +S +F P+ P+
Sbjct: 399 -YLSTFSALTPVMLMEPPSHMGIFLDFEAGEVSFYSVSD-GSHLHTYSQATFPGPLQPF 455
>gi|7705825 tripartite motif-containing 17 isoform 1 [Homo sapiens]
Length = 477
Score = 221 bits (563), Expect = 1e-57
Identities = 143/479 (29%), Positives = 237/479 (49%), Gaps = 44/479 (9%)
Query: 9 VKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGESS------CPVCRISY 62
++EE TC ICL+ T P+ CGH+FC+AC+ + +K+ KG CP CR
Sbjct: 10 LQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSWEKARGKKGRRKRKGSFPCPECREMS 69
Query: 63 QPENIRPNRHVANLVEKLREVKLSPEGQKVDHCARHGEKLLLFCQEDGKVICWLCERSQE 122
N+ PNR + + E ++ P QK D C H E L LFCQ+D IC +C S+E
Sbjct: 70 PQRNLLPNRLLTKVAEMAQQ---HPGLQKQDLCQEHHEPLKLFCQKDQSPICVVCRESRE 126
Query: 123 HRGHHTFPTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDKTNVL 182
HR H P EE Q Y++KL+ +E LR++ L+A + A W+ +++ + ++
Sbjct: 127 HRLHRVLPAEEAVQGYKLKLEEDMEYLREQITRTGNLQAREEQSLAEWQGKVKERRERIV 186
Query: 183 ADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHRLQGS 242
+FE++ L EE LQ LE EEE+ L S + +Q SL L+ LE R
Sbjct: 187 LEFEKMNLYLVEEEQRLLQALETEEEETASRLRESVACLDRQGHSLELLLLQLEERSTQG 246
Query: 243 VMELLQGVDGVIKRTENVTLKKPETFPKNQ-RRVFRAPDLKGMLEVFRELTDVRRYWVDV 301
+++LQ + + R NV+++ PE P + R V R P G +EV R + DV
Sbjct: 247 PLQMLQDMKEPLSRKNNVSVQCPEVAPPTRPRTVCRVP---GQIEVLRGFLE------DV 297
Query: 302 TVAPNNISCAVISEDKRQVSSPKPQIIYGARGTRYQTFVNFNYCTGILGSQSITSGKHYW 361
+ ++ + RQ + + G+ + + F +G + +SG+HYW
Sbjct: 298 VPDATSAYPYLLLYESRQ----RRYLGSSPEGSGFCSKDRFVAYPCAVGQTAFSSGRHYW 353
Query: 362 EV--DVSKKTAWILGVCAGFQPDAMCNIEKNENYQ--PKYGYWVIGLEEGVKCSAFQDSS 417
EV +++ W LGVC N+ + + P+ G+WV+ L +G K
Sbjct: 354 EVGMNITGDALWALGVCRD-------NVSRKDRVPKCPENGFWVVQLSKGTK-------- 398
Query: 418 FHTPSVPFIVPLSVIICPDRVGVFLDYEACTVSFFNITNHGFLIYKFSHCSFSQPVFPY 476
+ + + P+ ++ P +G+FLD+EA VSF+++++ G ++ +S +F P+ P+
Sbjct: 399 -YLSTFSALTPVMLMEPPSHMGIFLDFEAGEVSFYSVSD-GSHLHTYSQATFPGPLQPF 455
>gi|68160935 tripartite motif-containing 17 isoform 2 [Homo sapiens]
Length = 450
Score = 201 bits (510), Expect = 2e-51
Identities = 134/458 (29%), Positives = 224/458 (48%), Gaps = 44/458 (9%)
Query: 30 CGHSFCQACLTANHKKSMLDKGESS------CPVCRISYQPENIRPNRHVANLVEKLREV 83
CGH+FC+AC+ + +K+ KG CP CR N+ PNR + + E ++
Sbjct: 4 CGHNFCRACIQLSWEKARGKKGRRKRKGSFPCPECREMSPQRNLLPNRLLTKVAEMAQQ- 62
Query: 84 KLSPEGQKVDHCARHGEKLLLFCQEDGKVICWLCERSQEHRGHHTFPTEEVAQEYQVKLQ 143
P QK D C H E L LFCQ+D IC +C S+EHR H P EE Q Y++KL+
Sbjct: 63 --HPGLQKQDLCQEHHEPLKLFCQKDQSPICVVCRESREHRLHRVLPAEEAVQGYKLKLE 120
Query: 144 AALEMLRQKQQEAEELEADIREEKASWKTQIQYDKTNVLADFEQLRDILDWEESNELQNL 203
+E LR++ L+A + A W+ +++ + ++ +FE++ L EE LQ L
Sbjct: 121 EDMEYLREQITRTGNLQAREEQSLAEWQGKVKERRERIVLEFEKMNLYLVEEEQRLLQAL 180
Query: 204 EKEEEDILKSLTNSETEMVQQTQSLRELISDLEHRLQGSVMELLQGVDGVIKRTENVTLK 263
E EEE+ L S + +Q SL L+ LE R +++LQ + + R NV+++
Sbjct: 181 ETEEEETASRLRESVACLDRQGHSLELLLLQLEERSTQGPLQMLQDMKEPLSRKNNVSVQ 240
Query: 264 KPETFPKNQ-RRVFRAPDLKGMLEVFRELTDVRRYWVDVTVAPNNISCAVISEDKRQVSS 322
PE P + R V R P G +EV R + DV + ++ + RQ
Sbjct: 241 CPEVAPPTRPRTVCRVP---GQIEVLRGFLE------DVVPDATSAYPYLLLYESRQ--- 288
Query: 323 PKPQIIYGARGTRYQTFVNFNYCTGILGSQSITSGKHYWEV--DVSKKTAWILGVCAGFQ 380
+ + G+ + + F +G + +SG+HYWEV +++ W LGVC
Sbjct: 289 -RRYLGSSPEGSGFCSKDRFVAYPCAVGQTAFSSGRHYWEVGMNITGDALWALGVCRD-- 345
Query: 381 PDAMCNIEKNENYQ--PKYGYWVIGLEEGVKCSAFQDSSFHTPSVPFIVPLSVIICPDRV 438
N+ + + P+ G+WV+ L +G K + + + P+ ++ P +
Sbjct: 346 -----NVSRKDRVPKCPENGFWVVQLSKGTK---------YLSTFSALTPVMLMEPPSHM 391
Query: 439 GVFLDYEACTVSFFNITNHGFLIYKFSHCSFSQPVFPY 476
G+FLD+EA VSF+++++ G ++ +S +F P+ P+
Sbjct: 392 GIFLDFEAGEVSFYSVSD-GSHLHTYSQATFPGPLQPF 428
>gi|15011941 tripartite motif protein TRIM4 isoform beta [Homo
sapiens]
Length = 474
Score = 196 bits (499), Expect = 3e-50
Identities = 149/491 (30%), Positives = 231/491 (47%), Gaps = 53/491 (10%)
Query: 8 NVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGESSCPVCRISYQPENI 67
+++EE+TCPICL+ P+S++CGH+FC+ CL H+ G CP CR P +
Sbjct: 5 DIQEELTCPICLDYFQDPVSIECGHNFCRGCL---HRNWAPGGGPFPCPECRHPSAPAAL 61
Query: 68 RPNRHVANLVEKLREVKLSPEGQKVDHCARHGEKLLLFCQEDGKVICWLCERSQEHRGHH 127
RPN +A L EK + +L P + C RH E L LFC++D + +C +C SQEH+ H
Sbjct: 62 RPNWALARLTEKTQRRRLGPVPPGL--CGRHWEPLRLFCEDDQRPVCLVCRESQEHQTHA 119
Query: 128 TFPTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDKTNVLADFEQ 187
P +E + Y+ KL + L K ++ L+ + WK +I+ + + +F +
Sbjct: 120 MAPIDEAFESYREKLLKSQRNLVAKMKKVMHLQDVEVKNATQWKDKIKSQRMRISTEFSK 179
Query: 188 LRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHRLQGSVMELL 247
L + L EE LQ L KEEE+ K L + ++ Q SL++LI ++ + Q +ELL
Sbjct: 180 LHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQAPTLELL 239
Query: 248 QGVDGVIKRTE----NVTLKKPETFPKNQRRVFRAPDLKGMLEVFRELTDVRRYWVDVTV 303
Q V+ R+E N +L+ + + V + P +K ML+ F+ ++ + T
Sbjct: 240 QNPKEVLTRSEIQDVNYSLEAVKV-----KTVCQIPLMKEMLKRFQVAVNL----AEDTA 290
Query: 304 APNNISCAVISEDKRQVS-----------SPKPQIIYGARGTRYQTFV-NFNYCTGILGS 351
P V S++ R V S G R + FV F + +LG
Sbjct: 291 HPK----LVFSQEGRYVKNTASASSWPVFSSAWNYFAGWRNPQKTAFVERFQHLPCVLGK 346
Query: 352 QSITSGKHYWEVDVSKKTAWILGVCAGFQPDAMCNIEKNENYQPKYGYWVIGLEEGVKCS 411
TSGKHYWEV+ +GVC + D M I P G W I
Sbjct: 347 NVFTSGKHYWEVESRDSLEVAVGVC---REDVM-GITDRSKMSPDVGIWAI--------- 393
Query: 412 AFQDSSFHTPSVPFI-VPLSVIICPDRVGVFLDYEACTVSFFNITNHGFLIYKFSHCSFS 470
+ ++ + P + F P RVGV+LD VSF++ + G ++ FS S S
Sbjct: 394 -YWSAAGYWPLIGFPGTPTQQEPALHRVGVYLDRGTGNVSFYSAVD-GVHLHTFSCSSVS 451
Query: 471 --QPVFPYLNP 479
+P F +L+P
Sbjct: 452 RLRPFF-WLSP 461
>gi|31542779 tripartite motif family-like 1 [Homo sapiens]
Length = 468
Score = 187 bits (474), Expect = 2e-47
Identities = 144/505 (28%), Positives = 249/505 (49%), Gaps = 60/505 (11%)
Query: 5 ILVNVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGESSCPVCRISYQP 64
++ N++EE+TC ICL+ + P++ +CGHSFC CL + ++ SCP C + +
Sbjct: 6 LMENLREELTCFICLDYFSSPVTTECGHSFCLVCLLRSWEEH---NTPLSCPECWRTLEG 62
Query: 65 ENIRPNRHVANLVEKLREVKLSPEGQKVDHCARHGE-----KLLLFCQEDGKVICWLCER 119
+ + N + L R+++ S Q D +G K L ++ G
Sbjct: 63 PHFQSNERLGRLASIARQLR-SQVLQSEDEQGSYGRMPTTAKALSDDEQGGSAFV----- 116
Query: 120 SQEHRGHHTFPTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDKT 179
+Q H + + E + ++ KLQ L +LR +++EA+ + +E + + + K
Sbjct: 117 AQSHGANRVHLSSEAEEHHREKLQEILNLLRVRRKEAQAVLTHEKERVKLCQEETKTCKQ 176
Query: 180 NVLADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHRL 239
V++++ ++ L EE +LQ LE+EE++ ++ L N+E ++ QQ +SL ++I+ +E
Sbjct: 177 VVVSEYMKMHQFLKEEEQLQLQLLEQEEKENMRKLRNNEIKLTQQIRSLSKMIAQIESSS 236
Query: 240 QGSVMELLQGVDGVIKRTENVTLKKPETFPKNQRRVFRAPDLKGMLEVFRELTDVRRYWV 299
Q S E L+ V G ++R+E + L+ PE + + R +K ML R++
Sbjct: 237 QSSAFESLEEVRGALERSEPLLLQCPEA-TTTELSLCRITGMKEML---------RKFST 286
Query: 300 DVTVAPNNISC-AVISEDKRQVSSPKPQIIYGARGTRYQTFVN---FNYCTGILGSQSIT 355
++T+ P + V+SED + V YG G+R Q N F+ +LG+Q T
Sbjct: 287 EITLDPATANAYLVLSEDLKSVK-------YG--GSRQQLPDNPERFDQSATVLGTQIFT 337
Query: 356 SGKHYWEVDVSKKTAWILGVCAGFQPDAMCNIEKNENYQPKYG--YWVIGLEEGVKCSAF 413
SG+HYWEV+V KT W +G+C ++ + N G + +IGL+ G S +
Sbjct: 338 SGRHYWEVEVGNKTEWEVGICKD-------SVSRKGNLPKPPGDLFSLIGLKIGDDYSLW 390
Query: 414 QDSSFHTPSVPFIVPLSVIICPDRVGVFLDYEACTVSFFNITNHGFLIYKFSHCSFSQPV 473
S V +C +VGVFLDYE+ ++F+N T+ LIY F SF + +
Sbjct: 391 VSSPLKGQHV------REPVC--KVGVFLDYESGHIAFYNGTDES-LIYSFPQASFQEAL 441
Query: 474 FPYLNPRKCGV-----PMTLCSPSS 493
P +P P+T+CS +S
Sbjct: 442 RPIFSPCLPNEGTNTDPLTICSLNS 466
>gi|14670266 tripartite motif protein TRIM4 isoform alpha [Homo
sapiens]
Length = 500
Score = 184 bits (467), Expect = 2e-46
Identities = 151/517 (29%), Positives = 237/517 (45%), Gaps = 79/517 (15%)
Query: 8 NVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGESSCPVCRISYQPENI 67
+++EE+TCPICL+ P+S++CGH+FC+ CL H+ G CP CR P +
Sbjct: 5 DIQEELTCPICLDYFQDPVSIECGHNFCRGCL---HRNWAPGGGPFPCPECRHPSAPAAL 61
Query: 68 RPNRHVANLVEKLREVKLSPEGQKVDHCARHGEKLLLFCQEDGKVICWLCERSQEHRGHH 127
RPN +A L EK + +L P + C RH E L LFC++D + +C +C SQEH+ H
Sbjct: 62 RPNWALARLTEKTQRRRLGPVPPGL--CGRHWEPLRLFCEDDQRPVCLVCRESQEHQTHA 119
Query: 128 TFPTEEVAQEYQV----------KLQAALEMLRQKQQEAEELEA---------------D 162
P +E + Y+ K + +L +QE + L++ D
Sbjct: 120 MAPIDEAFESYRTGNFDIHVDEWKRRLIRLLLYHSKQEEKLLKSQRNLVAKMKKVMHLQD 179
Query: 163 IREEKAS-WKTQIQYDKTNVLADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEM 221
+ + A+ WK +I+ + + +F +L + L EE LQ L KEEE+ K L + ++
Sbjct: 180 VEVKNATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKL 239
Query: 222 VQQTQSLRELISDLEHRLQGSVMELLQGVDGVIKRTE----NVTLKKPETFPKNQRRVFR 277
Q SL++LI ++ + Q +ELLQ V+ R+E N +L+ + + V +
Sbjct: 240 NQTIASLKKLILEVGEKSQAPTLELLQNPKEVLTRSEIQDVNYSLEAVKV-----KTVCQ 294
Query: 278 APDLKGMLEVFRELTDVRRYWVDVTVAPNNISCAVISEDKRQVS-----------SPKPQ 326
P +K ML+ F+ ++ + T P V S++ R V S
Sbjct: 295 IPLMKEMLKRFQVAVNL----AEDTAHPK----LVFSQEGRYVKNTASASSWPVFSSAWN 346
Query: 327 IIYGARGTRYQTFV-NFNYCTGILGSQSITSGKHYWEVDVSKKTAWILGVCAGFQPDAMC 385
G R + FV F + +LG TSGKHYWEV+ +GVC + D M
Sbjct: 347 YFAGWRNPQKTAFVERFQHLPCVLGKNVFTSGKHYWEVESRDSLEVAVGVC---REDVM- 402
Query: 386 NIEKNENYQPKYGYWVIGLEEGVKCSAFQDSSFHTPSVPFI-VPLSVIICPDRVGVFLDY 444
I P G W I + ++ + P + F P RVGV+LD
Sbjct: 403 GITDRSKMSPDVGIWAI----------YWSAAGYWPLIGFPGTPTQQEPALHRVGVYLDR 452
Query: 445 EACTVSFFNITNHGFLIYKFSHCSFS--QPVFPYLNP 479
VSF++ + G ++ FS S S +P F +L+P
Sbjct: 453 GTGNVSFYSAVD-GVHLHTFSCSSVSRLRPFF-WLSP 487
>gi|209862805 SPRY domain containing 5 [Homo sapiens]
Length = 452
Score = 184 bits (466), Expect = 2e-46
Identities = 135/479 (28%), Positives = 222/479 (46%), Gaps = 38/479 (7%)
Query: 1 MASGILVNVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGESSCPVCRI 60
M SGIL + +TCPIC+ P+++DCGHSFC+ CL N + + + + C C+
Sbjct: 1 MNSGILQVFQRALTCPICMNYFLDPVTIDCGHSFCRPCLYLNWQDTAV---LAQCSECKK 57
Query: 61 SYQPENIRPNRHVANLVEKLREVKLSP-EGQKVDHCARHGEKLLLFCQEDGKVICWLCER 119
+ + N+ + + N+ R+ L + C H E +FC+ D ++C C
Sbjct: 58 TTRQRNLNTDICLKNMAFIARKASLRQFLSSEEQICGMHRETKKMFCEVDKSLLCLPCSN 117
Query: 120 SQEHRGHHTFPTEEVAQEYQVKLQAALEMLRQKQ-QEAEELEADIREEKASWKTQIQYDK 178
SQEHR H P E A+E + +L ++ L +K + L + + WK +
Sbjct: 118 SQEHRNHIHCPIEWAAEERREELLKKMQSLWEKACENLRNLNMETTRTRC-WKDYVSLRI 176
Query: 179 TNVLADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHR 238
+ A+++++ L EE + L+ L KE EDI + L S+ M + LR + DL+
Sbjct: 177 EAIRAEYQKMPAFLHEEEQHHLERLRKEGEDIFQQLNESKARMEHSRELLRGMYEDLKQM 236
Query: 239 LQGSVMELLQGVDGVIKRTENVTLKKPETFPKNQRRVFRAPDLKGMLEVFRELTDVRRYW 298
+ +ELLQ ++ R E++ L+ E P N A + G+L+ + +
Sbjct: 237 CHKADVELLQAFGDILHRYESLLLQVSE--PVNPE--LSAGPITGLLD------SLSGFR 286
Query: 299 VDVTVAPNNISCAV-ISEDKRQVSSPKPQIIYGARGTRYQTFVNFNYCTGILGSQSITSG 357
VD T+ P + + + D R ++ G + C + G+Q+ TSG
Sbjct: 287 VDFTLQPERANSHIFLCGDLRSMN-------VGCDPQDDPDITGKSECFLVWGAQAFTSG 339
Query: 358 KHYWEVDVSKKTAWILGVCAGFQPDAMCNIEKNENYQPKYGYWVIG-LEEGVKCSAFQDS 416
K+YWEV + W GVC + + +N+ + G +++G ++E CS F S
Sbjct: 340 KYYWEVHMGDSWNWAFGVCNNYWKEK----RQNDKIDGEEGLFLLGCVKEDTHCSLFTTS 395
Query: 417 SFHTPSVPFIVPLSVIICPDRVGVFLDYEACTVSFFNITNHGFLIYKFSHCSFSQPVFP 475
VP P S VG+FLD E TVSF ++ + LIY +CSFS P+ P
Sbjct: 396 PLVVQYVP--RPTST------VGLFLDCEGRTVSFVDV-DQSSLIYTIPNCSFSPPLRP 445
>gi|169202375 PREDICTED: tripartite motif-containing protein
64B-like [Homo sapiens]
Length = 449
Score = 184 bits (466), Expect = 2e-46
Identities = 140/479 (29%), Positives = 220/479 (45%), Gaps = 39/479 (8%)
Query: 1 MASGILVNVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGESSCPVCRI 60
M S L + E+ C IC+ P+++DCGHSFC+ CL ++ + CP CR
Sbjct: 1 MDSDDLQVFQNELICCICVNYFIDPVTIDCGHSFCRPCLCLCSEEG---RAPMRCPSCRK 57
Query: 61 SYQPENIRPNRHVANLVEKLREVKLSPEGQKVDHCARHGEKLLLFCQEDGKVICWLCERS 120
+ + N N + L R+ + + C H E LFC+ D +++C C S
Sbjct: 58 TSEKPNFNTNLVLKKLSSLARQTRPQNINSSDNICVLHEETKELFCEADKRLLCGPCSES 117
Query: 121 QEHRGHHTFPTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDKTN 180
EH H P A+E + KL ++ L + QE S K + K
Sbjct: 118 PEHMAHSHSPIGWAAEECREKLIKEMDYLWEINQETRNNLNQETSTFHSLKDYVSVRKRI 177
Query: 181 VLADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHRLQ 240
+ ++++ LD EE LQ LE+E E++ + L +S+ M Q + ++++ +L
Sbjct: 178 ITIQYQKMPIFLDEEEQRHLQALEREAEELFQQLQDSQVRMTQHLERMKDMYRELWETCH 237
Query: 241 GSVMELLQGVDGVIKRTENVTLKKPETFPKNQRRVFRAPDLKGMLEVFRELTDVRRYWVD 300
+ LLQ V V RT+ ++KP+ P N P+L + L + + VD
Sbjct: 238 MPDVVLLQDVRNVSARTDLAQMQKPQ--PVN-------PELTSWC-ITGVLDMLNNFRVD 287
Query: 301 VTVAPNNISCAV-ISEDKRQVSSPKPQIIYGARGTRYQTFVNFNYCTGILGSQSITSGKH 359
++ I C + +SED R V I+G T + G+Q+ TSGKH
Sbjct: 288 SALSTEMIPCYISLSEDVRYV-------IFGDDHLSAPTDPQGVDSFAVWGAQAFTSGKH 340
Query: 360 YWEVDVSKKTAWILGVCAGFQ-PDAMCNIEKNENYQPKYGYWVIGLEEGVKCSAFQDSSF 418
YWEVDV+ + WILGVC + DA I+ +E + L + + + S+
Sbjct: 341 YWEVDVTLSSNWILGVCRDSRTADANFVIDSDERF---------FLISSKRSNHYSLSTN 391
Query: 419 HTPSVPFIV-PLSVIICPDRVGVFLDYEACTVSFFNITNHGFLIYKFSHCSFSQPVFPY 476
P + ++ PL RVGVFLDY+ +VSFF+++ G LIY F SFS P+ P+
Sbjct: 392 SPPLIQYVQRPLG------RVGVFLDYDNGSVSFFDVSK-GSLIYGFPPSSFSSPLRPF 443
>gi|210147600 tripartite motif-containing 64 [Homo sapiens]
Length = 449
Score = 183 bits (465), Expect = 3e-46
Identities = 140/479 (29%), Positives = 220/479 (45%), Gaps = 39/479 (8%)
Query: 1 MASGILVNVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGESSCPVCRI 60
M S L + E+ C IC+ P+++DCGHSFC+ CL ++ + CP CR
Sbjct: 1 MDSDDLQVFQNELICCICVNYFIDPVTIDCGHSFCRPCLCLCSEEG---RAPMRCPSCRK 57
Query: 61 SYQPENIRPNRHVANLVEKLREVKLSPEGQKVDHCARHGEKLLLFCQEDGKVICWLCERS 120
+ N N + L R+ + + C H E LFC+ D +++C C S
Sbjct: 58 ISEKPNFNTNVVLKKLSSLARQTRPQNINSSDNICVLHEETKELFCEADKRLLCGPCSES 117
Query: 121 QEHRGHHTFPTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDKTN 180
EH H P A+E + KL ++ L + QE S K + K
Sbjct: 118 PEHMAHSHSPIGWAAEECREKLIKEMDYLWEINQETRNNLNQETRTFHSLKDYVSVRKRI 177
Query: 181 VLADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHRLQ 240
+ ++++ LD EE LQ LE+E E++ + L +S+ M Q + ++++ +L
Sbjct: 178 ITIQYQKMPIFLDEEEQRHLQALEREAEELFQQLQDSQVRMTQHLERMKDMYRELWETCH 237
Query: 241 GSVMELLQGVDGVIKRTENVTLKKPETFPKNQRRVFRAPDLKGMLEVFRELTDVRRYWVD 300
+ELLQ V V RT+ ++KP+ P N P+L + L + + VD
Sbjct: 238 VPDVELLQDVRNVSARTDLAQMQKPQ--PVN-------PELTSWC-ITGVLDMLNNFRVD 287
Query: 301 VTVAPNNISCAV-ISEDKRQVSSPKPQIIYGARGTRYQTFVNFNYCTGILGSQSITSGKH 359
++ I C + +SED R V I+G T + G+Q+ TSGKH
Sbjct: 288 SALSTEMIPCYISLSEDVRYV-------IFGDDHLSAPTDPQGVDSFAVWGAQAFTSGKH 340
Query: 360 YWEVDVSKKTAWILGVCAGFQ-PDAMCNIEKNENYQPKYGYWVIGLEEGVKCSAFQDSSF 418
YWEVDV+ + WILGVC + DA I+ +E + L + + + S+
Sbjct: 341 YWEVDVTLSSNWILGVCQDSRTADANFVIDSDERF---------FLISSKRSNHYSLSTN 391
Query: 419 HTPSVPFIV-PLSVIICPDRVGVFLDYEACTVSFFNITNHGFLIYKFSHCSFSQPVFPY 476
P + ++ PL +VGVFLDY+ +VSFF+++ G LIY F SFS P+ P+
Sbjct: 392 SPPLIQYVQRPLG------QVGVFLDYDNGSVSFFDVSK-GSLIYGFPPSSFSSPLRPF 443
>gi|89034675 PREDICTED: similar to hCG1802386 [Homo sapiens]
Length = 452
Score = 182 bits (462), Expect = 6e-46
Identities = 134/480 (27%), Positives = 218/480 (45%), Gaps = 36/480 (7%)
Query: 1 MASGILVNVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGESSCPVCRI 60
M SGIL + E+ CPIC+ P+++DCGHSFC+ C N + + + C C+
Sbjct: 1 MNSGILQVFQRELICPICMNYFIDPVTIDCGHSFCRPCFYLNWQDMAV---LAQCSKCKK 57
Query: 61 SYQPENIRPNRHVANLVEKLREVKLSPEGQKVDH-CARHGEKLLLFCQEDGKVICWLCER 119
+ + N++ N + N+ R+ L + C H E +FC+ D ++C LC
Sbjct: 58 TTRQRNLKTNICLKNMASIARKASLRQFLSSEEQICGTHRETKEMFCEVDKSLLCLLCSN 117
Query: 120 SQEHRGHHTFPTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDKT 179
SQEHR H PTE A+E + +L ++ L +K E WK +
Sbjct: 118 SQEHRNHRHCPTEWAAEERREELLRKMQSLWRKMCENHRNLNMATNRIRCWKDYVSLRIE 177
Query: 180 NVLADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHRL 239
+ A++ ++ EE L+ L+KE EDI + L S+ M + LR + DL
Sbjct: 178 AIRAEYHKMVAFFHEEEQRHLERLQKEGEDIFQQLNKSKARMEHSRELLRGMYEDLRQMC 237
Query: 240 QGSVMELLQGVDGVIKRTENVTLKKPETFPKNQRRVFRAPDLKGMLEVFRELTDVRRYWV 299
+V+ELLQ +++R E++ L+ E P N F A + G+++ ++ + V
Sbjct: 238 HKAVVELLQSFGDILQRYESLLLQVSE--PVNPE--FSAGPIIGLMD------RLKGFRV 287
Query: 300 DVTVAPNNISCAV-ISEDKRQVSSPKPQIIYGARGTRYQTFVNFNYCTGILGSQSITSGK 358
+T+ S + + D R + G + + C G+ SGK
Sbjct: 288 YLTLQHARASSHIFLHGDLRSMK-------VGCDPQHDPNITDKSECFLQWGADFFISGK 340
Query: 359 HYWEVDVSKKTAWILGVCAGFQPDAMCNIEKNENYQPKYGYWVIG-LEEGVKCSAFQDSS 417
YWE ++ W GVC + + +N+ + G +++G ++E CS F S
Sbjct: 341 FYWEFNMGHSWNWAFGVCHNYWKEK----RQNDMIDGEVGLFLLGCVKEDTHCSLFTTS- 395
Query: 418 FHTPSVPFIVPLSVIICPDRVGVFLDYEACTVSFFNITNHGFLIYKFSHCSFSQPVFPYL 477
P V VP D VG+FLD E TVSF ++ + LIY +CSFS P++P +
Sbjct: 396 ---PLVMQYVPRPT----DTVGLFLDCEGRTVSFVDV-DRSSLIYTIPNCSFSPPLWPII 447
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.134 0.411
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,041,342
Number of Sequences: 37866
Number of extensions: 937985
Number of successful extensions: 7379
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 282
Number of HSP's successfully gapped in prelim test: 522
Number of HSP's that attempted gapping in prelim test: 5475
Number of HSP's gapped (non-prelim): 1856
length of query: 493
length of database: 18,247,518
effective HSP length: 106
effective length of query: 387
effective length of database: 14,233,722
effective search space: 5508450414
effective search space used: 5508450414
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.