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Search of human proteins with 14670373
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|14670373 poly(rC) binding protein 4 isoform c [Homo sapiens]
(403 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|14670373 poly(rC) binding protein 4 isoform c [Homo sapiens] 790 0.0
gi|14670369 poly(rC) binding protein 4 isoform c [Homo sapiens] 790 0.0
gi|9966803 poly(rC) binding protein 4 isoform a [Homo sapiens] 673 0.0
gi|194306631 poly(rC) binding protein 3 isoform 1 [Homo sapiens] 379 e-105
gi|193083114 poly(rC) binding protein 2 isoform g [Homo sapiens] 370 e-102
gi|148833484 poly(rC) binding protein 2 isoform c [Homo sapiens] 367 e-101
gi|193083112 poly(rC) binding protein 2 isoform f [Homo sapiens] 361 e-100
gi|193083110 poly(rC) binding protein 2 isoform e [Homo sapiens] 350 1e-96
gi|14141166 poly(rC) binding protein 2 isoform b [Homo sapiens] 350 1e-96
gi|193083108 poly(rC) binding protein 2 isoform d [Homo sapiens] 345 5e-95
gi|14141168 poly(rC) binding protein 2 isoform a [Homo sapiens] 345 5e-95
gi|194306633 poly(rC) binding protein 3 isoform 2 [Homo sapiens] 336 2e-92
gi|222352151 poly(rC) binding protein 1 [Homo sapiens] 325 4e-89
gi|14165439 heterogeneous nuclear ribonucleoprotein K isoform a ... 100 4e-21
gi|14165435 heterogeneous nuclear ribonucleoprotein K isoform b ... 100 4e-21
gi|14165437 heterogeneous nuclear ribonucleoprotein K isoform a ... 100 4e-21
gi|17402900 far upstream element-binding protein [Homo sapiens] 84 2e-16
gi|154355000 KH-type splicing regulatory protein [Homo sapiens] 82 7e-16
gi|5902724 neuro-oncological ventral antigen 2 [Homo sapiens] 80 3e-15
gi|64085377 insulin-like growth factor 2 mRNA binding protein 2 ... 77 4e-14
gi|56549653 neuro-oncological ventral antigen 1 isoform 1 [Homo ... 76 6e-14
gi|56549651 neuro-oncological ventral antigen 1 isoform 2 [Homo ... 76 6e-14
gi|30795212 insulin-like growth factor 2 mRNA binding protein 3 ... 75 1e-13
gi|100816392 far upstream element (FUSE) binding protein 3 [Homo... 73 4e-13
gi|56118219 insulin-like growth factor 2 mRNA binding protein 2 ... 73 5e-13
gi|56237027 insulin-like growth factor 2 mRNA binding protein 1 ... 72 1e-12
gi|238624257 insulin-like growth factor 2 mRNA binding protein 1... 65 1e-10
gi|122937472 bicaudal C homolog 1 [Homo sapiens] 53 6e-07
gi|38683807 ankyrin repeat domain protein 17 isoform a [Homo sap... 52 7e-07
gi|38683816 ankyrin repeat domain protein 17 isoform b [Homo sap... 52 7e-07
>gi|14670373 poly(rC) binding protein 4 isoform c [Homo sapiens]
Length = 403
Score = 790 bits (2041), Expect = 0.0
Identities = 403/403 (100%), Positives = 403/403 (100%)
Query: 1 MSGSDGGLEEEPELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSCPE 60
MSGSDGGLEEEPELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSCPE
Sbjct: 1 MSGSDGGLEEEPELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSCPE 60
Query: 61 RITTITGSTAAVFHAVSMIAFKLDEDLCAAPANGGNVSRPPVTLRLVIPASQCGSLIGKA 120
RITTITGSTAAVFHAVSMIAFKLDEDLCAAPANGGNVSRPPVTLRLVIPASQCGSLIGKA
Sbjct: 61 RITTITGSTAAVFHAVSMIAFKLDEDLCAAPANGGNVSRPPVTLRLVIPASQCGSLIGKA 120
Query: 121 GTKIKEIRETTGAQVQVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVILESPPKGATI 180
GTKIKEIRETTGAQVQVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVILESPPKGATI
Sbjct: 121 GTKIKEIRETTGAQVQVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVILESPPKGATI 180
Query: 181 PYHPSLSLGTVLLSANQGFSVQGQYGAVTPAEVTKLQQLSSHAVPFATPSVVPGLDPGTQ 240
PYHPSLSLGTVLLSANQGFSVQGQYGAVTPAEVTKLQQLSSHAVPFATPSVVPGLDPGTQ
Sbjct: 181 PYHPSLSLGTVLLSANQGFSVQGQYGAVTPAEVTKLQQLSSHAVPFATPSVVPGLDPGTQ 240
Query: 241 TSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAEGAGERHVTITGSPVSIAL 300
TSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAEGAGERHVTITGSPVSIAL
Sbjct: 241 TSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAEGAGERHVTITGSPVSIAL 300
Query: 301 AQYLITACLETAKSTSGGTPSSAPADLPAPFSPPLTALPTAPPGLLGTPYAISLSNFIGL 360
AQYLITACLETAKSTSGGTPSSAPADLPAPFSPPLTALPTAPPGLLGTPYAISLSNFIGL
Sbjct: 301 AQYLITACLETAKSTSGGTPSSAPADLPAPFSPPLTALPTAPPGLLGTPYAISLSNFIGL 360
Query: 361 KPMPFLALPPASPGPPPGLAAYTAKMAAANGSKKAERQKFSPY 403
KPMPFLALPPASPGPPPGLAAYTAKMAAANGSKKAERQKFSPY
Sbjct: 361 KPMPFLALPPASPGPPPGLAAYTAKMAAANGSKKAERQKFSPY 403
>gi|14670369 poly(rC) binding protein 4 isoform c [Homo sapiens]
Length = 403
Score = 790 bits (2041), Expect = 0.0
Identities = 403/403 (100%), Positives = 403/403 (100%)
Query: 1 MSGSDGGLEEEPELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSCPE 60
MSGSDGGLEEEPELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSCPE
Sbjct: 1 MSGSDGGLEEEPELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSCPE 60
Query: 61 RITTITGSTAAVFHAVSMIAFKLDEDLCAAPANGGNVSRPPVTLRLVIPASQCGSLIGKA 120
RITTITGSTAAVFHAVSMIAFKLDEDLCAAPANGGNVSRPPVTLRLVIPASQCGSLIGKA
Sbjct: 61 RITTITGSTAAVFHAVSMIAFKLDEDLCAAPANGGNVSRPPVTLRLVIPASQCGSLIGKA 120
Query: 121 GTKIKEIRETTGAQVQVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVILESPPKGATI 180
GTKIKEIRETTGAQVQVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVILESPPKGATI
Sbjct: 121 GTKIKEIRETTGAQVQVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVILESPPKGATI 180
Query: 181 PYHPSLSLGTVLLSANQGFSVQGQYGAVTPAEVTKLQQLSSHAVPFATPSVVPGLDPGTQ 240
PYHPSLSLGTVLLSANQGFSVQGQYGAVTPAEVTKLQQLSSHAVPFATPSVVPGLDPGTQ
Sbjct: 181 PYHPSLSLGTVLLSANQGFSVQGQYGAVTPAEVTKLQQLSSHAVPFATPSVVPGLDPGTQ 240
Query: 241 TSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAEGAGERHVTITGSPVSIAL 300
TSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAEGAGERHVTITGSPVSIAL
Sbjct: 241 TSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAEGAGERHVTITGSPVSIAL 300
Query: 301 AQYLITACLETAKSTSGGTPSSAPADLPAPFSPPLTALPTAPPGLLGTPYAISLSNFIGL 360
AQYLITACLETAKSTSGGTPSSAPADLPAPFSPPLTALPTAPPGLLGTPYAISLSNFIGL
Sbjct: 301 AQYLITACLETAKSTSGGTPSSAPADLPAPFSPPLTALPTAPPGLLGTPYAISLSNFIGL 360
Query: 361 KPMPFLALPPASPGPPPGLAAYTAKMAAANGSKKAERQKFSPY 403
KPMPFLALPPASPGPPPGLAAYTAKMAAANGSKKAERQKFSPY
Sbjct: 361 KPMPFLALPPASPGPPPGLAAYTAKMAAANGSKKAERQKFSPY 403
>gi|9966803 poly(rC) binding protein 4 isoform a [Homo sapiens]
Length = 424
Score = 673 bits (1737), Expect = 0.0
Identities = 356/413 (86%), Positives = 358/413 (86%), Gaps = 55/413 (13%)
Query: 46 QSSARITISEGSCPERITTITGSTAAVFHAVSMIAFKLDEDLCAAPANGGNVSRPPVTLR 105
QSSARITISEGSCPERITTITGSTAAVFHAVSMIAFKLDEDLCAAPANGGNVSRPPVTLR
Sbjct: 12 QSSARITISEGSCPERITTITGSTAAVFHAVSMIAFKLDEDLCAAPANGGNVSRPPVTLR 71
Query: 106 LVIPASQCGSLIGKAGTKIK---EIR---------------------------------- 128
LVIPASQCGSLIGKAGTKIK E+R
Sbjct: 72 LVIPASQCGSLIGKAGTKIKEIREVRGEIYHPQGIRGKGAVVRGVLGLWRPPHLESSEPG 131
Query: 129 ------------------ETTGAQVQVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVI 170
+TTGAQVQVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVI
Sbjct: 132 QPFSGLWEQPEVAPVLCLQTTGAQVQVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVI 191
Query: 171 LESPPKGATIPYHPSLSLGTVLLSANQGFSVQGQYGAVTPAEVTKLQQLSSHAVPFATPS 230
LESPPKGATIPYHPSLSLGTVLLSANQGFSVQGQYGAVTPAEVTKLQQLSSHAVPFATPS
Sbjct: 192 LESPPKGATIPYHPSLSLGTVLLSANQGFSVQGQYGAVTPAEVTKLQQLSSHAVPFATPS 251
Query: 231 VVPGLDPGTQTSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAEGAGERHVT 290
VVPGLDPGTQTSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAEGAGERHVT
Sbjct: 252 VVPGLDPGTQTSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAEGAGERHVT 311
Query: 291 ITGSPVSIALAQYLITACLETAKSTSGGTPSSAPADLPAPFSPPLTALPTAPPGLLGTPY 350
ITGSPVSIALAQYLITACLETAKSTSGGTPSSAPADLPAPFSPPLTALPTAPPGLLGTPY
Sbjct: 312 ITGSPVSIALAQYLITACLETAKSTSGGTPSSAPADLPAPFSPPLTALPTAPPGLLGTPY 371
Query: 351 AISLSNFIGLKPMPFLALPPASPGPPPGLAAYTAKMAAANGSKKAERQKFSPY 403
AISLSNFIGLKPMPFLALPPASPGPPPGLAAYTAKMAAANGSKKAERQKFSPY
Sbjct: 372 AISLSNFIGLKPMPFLALPPASPGPPPGLAAYTAKMAAANGSKKAERQKFSPY 424
Score = 39.3 bits (90), Expect = 0.006
Identities = 30/91 (32%), Positives = 45/91 (49%), Gaps = 7/91 (7%)
Query: 17 TLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITI---SEGSCPERITTITGSTAAVF 73
T + L+ +G +IG++G + IR+ S A I I +EG+ ER TITGS ++
Sbjct: 262 TSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAEGA-GERHVTITGSPVSIA 320
Query: 74 HAVSMIAFKLDEDLCAAPANGGNVSRPPVTL 104
A +I L+ A +GG S P L
Sbjct: 321 LAQYLITACLE---TAKSTSGGTPSSAPADL 348
>gi|194306631 poly(rC) binding protein 3 isoform 1 [Homo sapiens]
Length = 371
Score = 379 bits (972), Expect = e-105
Identities = 198/333 (59%), Positives = 242/333 (72%), Gaps = 25/333 (7%)
Query: 11 EPELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSCPERITTITGSTA 70
E L++TLT+R+LMHGKEVGSIIGKKGETVK++RE+S ARI ISEG+CPERI TITG T
Sbjct: 39 EGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPERIVTITGPTD 98
Query: 71 AVFHAVSMIAFKLDEDLCAAPANGGNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRET 130
A+F A +MIA+K +ED+ + +N S+PPVTLRLV+PASQCGSLIGK G+KIKEIRE+
Sbjct: 99 AIFKAFAMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRES 158
Query: 131 TGAQVQVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVILESPPKGATIPYHPSLSLGT 190
TGAQVQVAGD+LPNSTERAVT+SG PDAII CV+QIC V+LESPPKGATIPY P +
Sbjct: 159 TGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLESPPKGATIPYRPKPASTP 218
Query: 191 VLLSANQGFSVQGQYGAVTPAEVTKLQQLSSHAVPF----ATPSVVP------------- 233
V+ + Q +++QGQY P ++TKL QL+ PF T P
Sbjct: 219 VIFAGGQAYTIQGQYAIPHPDQLTKLHQLAMQQTPFPPLGQTNPAFPGEKLPLHSSEEAQ 278
Query: 234 -------GLDPGTQTSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAEGAGE 286
GLD S+ E +PNDLIGC+IGRQG+KI+EIRQMSGA IKI N EG+ E
Sbjct: 279 NLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSE 338
Query: 287 RHVTITGSPVSIALAQYLITACLETAKSTSGGT 319
R +TITG+P +I+LAQYLI A L T++ T GT
Sbjct: 339 RQITITGTPANISLAQYLINARL-TSEVTGMGT 370
>gi|193083114 poly(rC) binding protein 2 isoform g [Homo sapiens]
Length = 318
Score = 370 bits (949), Expect = e-102
Identities = 192/316 (60%), Positives = 236/316 (74%), Gaps = 8/316 (2%)
Query: 11 EPELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSCPERITTITGSTA 70
E L++TLT+R+LMHGKEVGSIIGKKGE+VK++RE+S ARI ISEG+CPERI T+ G T
Sbjct: 7 EGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIITLAGPTN 66
Query: 71 AVFHAVSMIAFKLDEDLCAAPANGGNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRET 130
A+F A +MI KL+ED+ ++ N SRPPVTLRLV+PASQCGSLIGK G KIKEIRE+
Sbjct: 67 AIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRES 126
Query: 131 TGAQVQVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVILESPPKGATIPYHPSLSLGT 190
TGAQVQVAGD+LPNSTERA+T++G+P +II CV+QIC V+LESPPKG TIPY P S
Sbjct: 127 TGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKPSSSP 186
Query: 191 VLLSANQGFSVQGQYGAVTPAEVTKLQQLSSHAVPF----ATPSVVPGLDPGTQTSSQEF 246
V+ + Q +++QGQY A+ ++TKL QL+ F GLD QT+S E
Sbjct: 187 VIFAGGQAYTIQGQY-AIPQPDLTKLHQLAMQQSHFPMTHGNTGFSAGLDASAQTTSHEL 245
Query: 247 LVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAEGAGERHVTITGSPVSIALAQYLIT 306
+PNDLIGC+IGRQG+KI+EIRQMSGA IKI N EG+ +R VTITGS SI+LAQYLI
Sbjct: 246 TIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLIN 305
Query: 307 ACLETAKSTSGGTPSS 322
L S +GG SS
Sbjct: 306 VRL---SSETGGMGSS 318
>gi|148833484 poly(rC) binding protein 2 isoform c [Homo sapiens]
Length = 331
Score = 367 bits (941), Expect = e-101
Identities = 195/329 (59%), Positives = 242/329 (73%), Gaps = 21/329 (6%)
Query: 11 EPELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSCPERITTITGSTA 70
E L++TLT+R+LMHGKEVGSIIGKKGE+VK++RE+S ARI ISEG+CPERI T+ G T
Sbjct: 7 EGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIITLAGPTN 66
Query: 71 AVFHAVSMIAFKLDEDLCAAPANGGNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRET 130
A+F A +MI KL+ED+ ++ N SRPPVTLRLV+PASQCGSLIGK G KIKEIRE+
Sbjct: 67 AIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRES 126
Query: 131 TGAQVQVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVILESPPKGATIPYHPSLSLGT 190
TGAQVQVAGD+LPNSTERA+T++G+P +II CV+QIC V+LESPPKG TIPY P S
Sbjct: 127 TGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKPSSSP 186
Query: 191 VLLSANQGFSVQGQYGAVTPAEVTKLQQLS---SH-----------AVPFATPSVV---P 233
V+ + Q +++QGQY A+ ++TKL QL+ SH + ++P V
Sbjct: 187 VIFAGGQAYTIQGQY-AIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWA 245
Query: 234 GLDPGTQTSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAEGAGERHVTITG 293
GLD QT+S E +PNDLIGC+IGRQG+KI+EIRQMSGA IKI N EG+ +R VTITG
Sbjct: 246 GLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITG 305
Query: 294 SPVSIALAQYLITACLETAKSTSGGTPSS 322
S SI+LAQYLI L S +GG SS
Sbjct: 306 SAASISLAQYLINVRL---SSETGGMGSS 331
>gi|193083112 poly(rC) binding protein 2 isoform f [Homo sapiens]
Length = 335
Score = 361 bits (926), Expect = e-100
Identities = 195/333 (58%), Positives = 242/333 (72%), Gaps = 25/333 (7%)
Query: 11 EPELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSCPERITTITGSTA 70
E L++TLT+R+LMHGKEVGSIIGKKGE+VK++RE+S ARI ISEG+CPERI T+ G T
Sbjct: 7 EGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIITLAGPTN 66
Query: 71 AVFHAVSMIAFKLDEDLCAAPANGGNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRET 130
A+F A +MI KL+ED+ ++ N SRPPVTLRLV+PASQCGSLIGK G KIKEIRE+
Sbjct: 67 AIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRES 126
Query: 131 TGAQVQVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVILE----SPPKGATIPYHPSL 186
TGAQVQVAGD+LPNSTERA+T++G+P +II CV+QIC V+LE SPPKG TIPY P
Sbjct: 127 TGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTIPYRPKP 186
Query: 187 SLGTVLLSANQGFSVQGQYGAVTPAEVTKLQQLS---SH-----------AVPFATPSVV 232
S V+ + Q +++QGQY A+ ++TKL QL+ SH + ++P V
Sbjct: 187 SSSPVIFAGGQAYTIQGQY-AIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVK 245
Query: 233 ---PGLDPGTQTSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAEGAGERHV 289
GLD QT+S E +PNDLIGC+IGRQG+KI+EIRQMSGA IKI N EG+ +R V
Sbjct: 246 GYWAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQV 305
Query: 290 TITGSPVSIALAQYLITACLETAKSTSGGTPSS 322
TITGS SI+LAQYLI L S +GG SS
Sbjct: 306 TITGSAASISLAQYLINVRL---SSETGGMGSS 335
>gi|193083110 poly(rC) binding protein 2 isoform e [Homo sapiens]
Length = 361
Score = 350 bits (899), Expect = 1e-96
Identities = 195/359 (54%), Positives = 242/359 (67%), Gaps = 51/359 (14%)
Query: 11 EPELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSCPERITTITGSTA 70
E L++TLT+R+LMHGKEVGSIIGKKGE+VK++RE+S ARI ISEG+CPERI T+ G T
Sbjct: 7 EGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIITLAGPTN 66
Query: 71 AVFHAVSMIAFKLDEDLCAAPANGGNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRET 130
A+F A +MI KL+ED+ ++ N SRPPVTLRLV+PASQCGSLIGK G KIKEIRE+
Sbjct: 67 AIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRES 126
Query: 131 TGAQVQVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVILESPPKGATIPYHPSLSLGT 190
TGAQVQVAGD+LPNSTERA+T++G+P +II CV+QIC V+LESPPKG TIPY P S
Sbjct: 127 TGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKPSSSP 186
Query: 191 VLLSANQ-------------------------------GFSVQGQYGAVTPAEVTKLQQL 219
V+ + Q +++QGQY A+ ++TKL QL
Sbjct: 187 VIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQY-AIPQPDLTKLHQL 245
Query: 220 S---SH-----------AVPFATPSVVP--GLDPGTQTSSQEFLVPNDLIGCVIGRQGSK 263
+ SH + ++P V GLD QT+S E +PNDLIGC+IGRQG+K
Sbjct: 246 AMQQSHFPMTHGNTGFSGIESSSPEVKGYWGLDASAQTTSHELTIPNDLIGCIIGRQGAK 305
Query: 264 ISEIRQMSGAHIKIGNQAEGAGERHVTITGSPVSIALAQYLITACLETAKSTSGGTPSS 322
I+EIRQMSGA IKI N EG+ +R VTITGS SI+LAQYLI L S +GG SS
Sbjct: 306 INEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRL---SSETGGMGSS 361
Score = 65.9 bits (159), Expect = 6e-11
Identities = 68/283 (24%), Positives = 114/283 (40%), Gaps = 70/283 (24%)
Query: 102 VTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPNSTERAVTVSGVPDAIIL 161
+T+RL++ + GS+IGK G +K++RE +GA++ ++ N ER +T++G +AI
Sbjct: 14 LTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEG---NCPERIITLAGPTNAIFK 70
Query: 162 CVRQICAVILESPPKGATIPYHPSLSLGTVLLSANQGFSVQGQYGAVTPAEVTKLQQLSS 221
I + KL++ S
Sbjct: 71 AFAMI----------------------------------------------IDKLEEDIS 84
Query: 222 HAVPFATPSVVPGLDPGTQTSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKI-GNQ 280
++ +T + P + + +VP G +IG+ G KI EIR+ +GA +++ G+
Sbjct: 85 SSMTNSTAASRPPV-------TLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDM 137
Query: 281 AEGAGERHVTITGSPVSIALAQYLITACLETAKSTSGGTPSSAPADLPAPFSPPLTALPT 340
+ ER +TI G P SI +E K S P + P+ P ++ P
Sbjct: 138 LPNSTERAITIAGIPQSI----------IECVKQICVVMLESPPKGVTIPYRPKPSSSPV 187
Query: 341 APPGLLGTPYAISLSNFIGLKPMPFLALPPASPGPPPGLAAYT 383
G Y+ + P + L P GPP L AYT
Sbjct: 188 IFAGGQDR-YSTGSDSASFPHTTPSMCLNPDLEGPP--LEAYT 227
>gi|14141166 poly(rC) binding protein 2 isoform b [Homo sapiens]
Length = 362
Score = 350 bits (899), Expect = 1e-96
Identities = 195/360 (54%), Positives = 242/360 (67%), Gaps = 52/360 (14%)
Query: 11 EPELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSCPERITTITGSTA 70
E L++TLT+R+LMHGKEVGSIIGKKGE+VK++RE+S ARI ISEG+CPERI T+ G T
Sbjct: 7 EGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIITLAGPTN 66
Query: 71 AVFHAVSMIAFKLDEDLCAAPANGGNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRET 130
A+F A +MI KL+ED+ ++ N SRPPVTLRLV+PASQCGSLIGK G KIKEIRE+
Sbjct: 67 AIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRES 126
Query: 131 TGAQVQVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVILESPPKGATIPYHPSLSLGT 190
TGAQVQVAGD+LPNSTERA+T++G+P +II CV+QIC V+LESPPKG TIPY P S
Sbjct: 127 TGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKPSSSP 186
Query: 191 VLLSANQ-------------------------------GFSVQGQYGAVTPAEVTKLQQL 219
V+ + Q +++QGQY A+ ++TKL QL
Sbjct: 187 VIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQY-AIPQPDLTKLHQL 245
Query: 220 S---SH-----------AVPFATPSVV---PGLDPGTQTSSQEFLVPNDLIGCVIGRQGS 262
+ SH + ++P V GLD QT+S E +PNDLIGC+IGRQG+
Sbjct: 246 AMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLIGCIIGRQGA 305
Query: 263 KISEIRQMSGAHIKIGNQAEGAGERHVTITGSPVSIALAQYLITACLETAKSTSGGTPSS 322
KI+EIRQMSGA IKI N EG+ +R VTITGS SI+LAQYLI L S +GG SS
Sbjct: 306 KINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRL---SSETGGMGSS 362
Score = 65.9 bits (159), Expect = 6e-11
Identities = 68/283 (24%), Positives = 114/283 (40%), Gaps = 70/283 (24%)
Query: 102 VTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPNSTERAVTVSGVPDAIIL 161
+T+RL++ + GS+IGK G +K++RE +GA++ ++ N ER +T++G +AI
Sbjct: 14 LTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEG---NCPERIITLAGPTNAIFK 70
Query: 162 CVRQICAVILESPPKGATIPYHPSLSLGTVLLSANQGFSVQGQYGAVTPAEVTKLQQLSS 221
I + KL++ S
Sbjct: 71 AFAMI----------------------------------------------IDKLEEDIS 84
Query: 222 HAVPFATPSVVPGLDPGTQTSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKI-GNQ 280
++ +T + P + + +VP G +IG+ G KI EIR+ +GA +++ G+
Sbjct: 85 SSMTNSTAASRPPV-------TLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDM 137
Query: 281 AEGAGERHVTITGSPVSIALAQYLITACLETAKSTSGGTPSSAPADLPAPFSPPLTALPT 340
+ ER +TI G P SI +E K S P + P+ P ++ P
Sbjct: 138 LPNSTERAITIAGIPQSI----------IECVKQICVVMLESPPKGVTIPYRPKPSSSPV 187
Query: 341 APPGLLGTPYAISLSNFIGLKPMPFLALPPASPGPPPGLAAYT 383
G Y+ + P + L P GPP L AYT
Sbjct: 188 IFAGGQDR-YSTGSDSASFPHTTPSMCLNPDLEGPP--LEAYT 227
>gi|193083108 poly(rC) binding protein 2 isoform d [Homo sapiens]
Length = 365
Score = 345 bits (884), Expect = 5e-95
Identities = 195/363 (53%), Positives = 242/363 (66%), Gaps = 55/363 (15%)
Query: 11 EPELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSCPERITTITGSTA 70
E L++TLT+R+LMHGKEVGSIIGKKGE+VK++RE+S ARI ISEG+CPERI T+ G T
Sbjct: 7 EGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIITLAGPTN 66
Query: 71 AVFHAVSMIAFKLDEDLCAAPANGGNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRET 130
A+F A +MI KL+ED+ ++ N SRPPVTLRLV+PASQCGSLIGK G KIKEIRE+
Sbjct: 67 AIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRES 126
Query: 131 TGAQVQVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVILE----SPPKGATIPYHPSL 186
TGAQVQVAGD+LPNSTERA+T++G+P +II CV+QIC V+LE SPPKG TIPY P
Sbjct: 127 TGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTIPYRPKP 186
Query: 187 SLGTVLLSANQ-------------------------------GFSVQGQYGAVTPAEVTK 215
S V+ + Q +++QGQY A+ ++TK
Sbjct: 187 SSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQY-AIPQPDLTK 245
Query: 216 LQQLS---SH-----------AVPFATPSVVP--GLDPGTQTSSQEFLVPNDLIGCVIGR 259
L QL+ SH + ++P V GLD QT+S E +PNDLIGC+IGR
Sbjct: 246 LHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWGLDASAQTTSHELTIPNDLIGCIIGR 305
Query: 260 QGSKISEIRQMSGAHIKIGNQAEGAGERHVTITGSPVSIALAQYLITACLETAKSTSGGT 319
QG+KI+EIRQMSGA IKI N EG+ +R VTITGS SI+LAQYLI L S +GG
Sbjct: 306 QGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRL---SSETGGM 362
Query: 320 PSS 322
SS
Sbjct: 363 GSS 365
Score = 67.0 bits (162), Expect = 3e-11
Identities = 69/284 (24%), Positives = 116/284 (40%), Gaps = 68/284 (23%)
Query: 102 VTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPNSTERAVTVSGVPDAIIL 161
+T+RL++ + GS+IGK G +K++RE +GA++ ++ N ER +T++G +AI
Sbjct: 14 LTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEG---NCPERIITLAGPTNAIFK 70
Query: 162 CVRQICAVILESPPKGATIPYHPSLSLGTVLLSANQGFSVQGQYGAVTPAEVTKLQQLSS 221
I + KL++ S
Sbjct: 71 AFAMI----------------------------------------------IDKLEEDIS 84
Query: 222 HAVPFATPSVVPGLDPGTQTSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKI-GNQ 280
++ +T + P + + +VP G +IG+ G KI EIR+ +GA +++ G+
Sbjct: 85 SSMTNSTAASRPPV-------TLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDM 137
Query: 281 AEGAGERHVTITGSPVS-IALAQYLITACLETAKSTSGGTPSSAPADLPAPFSPPLTALP 339
+ ER +TI G P S I + + LET S P + P+ P ++ P
Sbjct: 138 LPNSTERAITIAGIPQSIIECVKQICVVMLETLS-------QSPPKGVTIPYRPKPSSSP 190
Query: 340 TAPPGLLGTPYAISLSNFIGLKPMPFLALPPASPGPPPGLAAYT 383
G Y+ + P + L P GPP L AYT
Sbjct: 191 VIFAGGQDR-YSTGSDSASFPHTTPSMCLNPDLEGPP--LEAYT 231
>gi|14141168 poly(rC) binding protein 2 isoform a [Homo sapiens]
Length = 366
Score = 345 bits (884), Expect = 5e-95
Identities = 195/364 (53%), Positives = 242/364 (66%), Gaps = 56/364 (15%)
Query: 11 EPELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSCPERITTITGSTA 70
E L++TLT+R+LMHGKEVGSIIGKKGE+VK++RE+S ARI ISEG+CPERI T+ G T
Sbjct: 7 EGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIITLAGPTN 66
Query: 71 AVFHAVSMIAFKLDEDLCAAPANGGNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRET 130
A+F A +MI KL+ED+ ++ N SRPPVTLRLV+PASQCGSLIGK G KIKEIRE+
Sbjct: 67 AIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRES 126
Query: 131 TGAQVQVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVILE----SPPKGATIPYHPSL 186
TGAQVQVAGD+LPNSTERA+T++G+P +II CV+QIC V+LE SPPKG TIPY P
Sbjct: 127 TGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTIPYRPKP 186
Query: 187 SLGTVLLSANQ-------------------------------GFSVQGQYGAVTPAEVTK 215
S V+ + Q +++QGQY A+ ++TK
Sbjct: 187 SSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQY-AIPQPDLTK 245
Query: 216 LQQLS---SH-----------AVPFATPSVV---PGLDPGTQTSSQEFLVPNDLIGCVIG 258
L QL+ SH + ++P V GLD QT+S E +PNDLIGC+IG
Sbjct: 246 LHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLIGCIIG 305
Query: 259 RQGSKISEIRQMSGAHIKIGNQAEGAGERHVTITGSPVSIALAQYLITACLETAKSTSGG 318
RQG+KI+EIRQMSGA IKI N EG+ +R VTITGS SI+LAQYLI L S +GG
Sbjct: 306 RQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRL---SSETGG 362
Query: 319 TPSS 322
SS
Sbjct: 363 MGSS 366
Score = 67.0 bits (162), Expect = 3e-11
Identities = 69/284 (24%), Positives = 116/284 (40%), Gaps = 68/284 (23%)
Query: 102 VTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPNSTERAVTVSGVPDAIIL 161
+T+RL++ + GS+IGK G +K++RE +GA++ ++ N ER +T++G +AI
Sbjct: 14 LTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEG---NCPERIITLAGPTNAIFK 70
Query: 162 CVRQICAVILESPPKGATIPYHPSLSLGTVLLSANQGFSVQGQYGAVTPAEVTKLQQLSS 221
I + KL++ S
Sbjct: 71 AFAMI----------------------------------------------IDKLEEDIS 84
Query: 222 HAVPFATPSVVPGLDPGTQTSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKI-GNQ 280
++ +T + P + + +VP G +IG+ G KI EIR+ +GA +++ G+
Sbjct: 85 SSMTNSTAASRPPV-------TLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDM 137
Query: 281 AEGAGERHVTITGSPVS-IALAQYLITACLETAKSTSGGTPSSAPADLPAPFSPPLTALP 339
+ ER +TI G P S I + + LET S P + P+ P ++ P
Sbjct: 138 LPNSTERAITIAGIPQSIIECVKQICVVMLETLS-------QSPPKGVTIPYRPKPSSSP 190
Query: 340 TAPPGLLGTPYAISLSNFIGLKPMPFLALPPASPGPPPGLAAYT 383
G Y+ + P + L P GPP L AYT
Sbjct: 191 VIFAGGQDR-YSTGSDSASFPHTTPSMCLNPDLEGPP--LEAYT 231
>gi|194306633 poly(rC) binding protein 3 isoform 2 [Homo sapiens]
Length = 345
Score = 336 bits (862), Expect = 2e-92
Identities = 185/310 (59%), Positives = 223/310 (71%), Gaps = 5/310 (1%)
Query: 11 EPELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSCPERITTITGSTA 70
E L++TLT+R+LMHGKEVGSIIGKKGETVK++RE+S ARI ISEG+CPERI TITG T
Sbjct: 39 EGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPERIVTITGPTD 98
Query: 71 AVFHAVSMIAFKLDEDLCAAPANGGNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRET 130
A+F A +MIA+K +ED+ + +N S+PPVTLRLV+PASQCGSLIGK G+KIKEIRE+
Sbjct: 99 AIFKAFAMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRES 158
Query: 131 TGAQVQVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVILES-PPKGATIPYHPSLSLG 189
TGAQVQVAGD+LPNSTERAVT+SG PDAII CV+QIC V+LE+ +G HP L+
Sbjct: 159 TGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLEAYTIQGQYAIPHPDLTKL 218
Query: 190 TVLLSANQGFSVQGQYGAVTPAEVTKLQQLSSHAVPFATPSVVPGLDPGTQTSSQEFLVP 249
L F GQ P E L S A S GLD S+ E +P
Sbjct: 219 HQLAMQQTPFPPLGQTNPAFPGEKLPLHS-SEEAQNLMGQS--SGLDASPPASTHELTIP 275
Query: 250 NDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAEGAGERHVTITGSPVSIALAQYLITACL 309
NDLIGC+IGRQG+KI+EIRQMSGA IKI N EG+ ER +TITG+P +I+LAQYLI A L
Sbjct: 276 NDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSERQITITGTPANISLAQYLINARL 335
Query: 310 ETAKSTSGGT 319
T++ T GT
Sbjct: 336 -TSEVTGMGT 344
>gi|222352151 poly(rC) binding protein 1 [Homo sapiens]
Length = 356
Score = 325 bits (833), Expect = 4e-89
Identities = 186/353 (52%), Positives = 236/353 (66%), Gaps = 47/353 (13%)
Query: 5 DGGLEEEPELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSCPERITT 64
D G+ E L++TLT+R+LMHGKEVGSIIGKKGE+VKRIRE+S ARI ISEG+CPERI T
Sbjct: 2 DAGVTESG-LNVTLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGNCPERIIT 60
Query: 65 ITGSTAAVFHAVSMIAFKLDEDLCAAPANGGNVSRPPVTLRLVIPASQCGSLIGKAGTKI 124
+TG T A+F A +MI KL+ED+ ++ N SRPPVTLRLV+PA+QCGSLIGK G KI
Sbjct: 61 LTGPTNAIFKAFAMIIDKLEEDINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKI 120
Query: 125 KEIRETTGAQVQVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVILES---PPKG--AT 179
KEIRE+TGAQVQVAGD+LPNSTERA+T++GVP ++ CV+QIC V+LE+ P+G T
Sbjct: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGVPQSVTECVKQICLVMLETLSQSPQGRVMT 180
Query: 180 IPYHPSLSLGTVLLSANQ----------------------GFSVQGQYGAVTPAEVTKLQ 217
IPY P + V+ + Q +S+QGQ+ ++P ++ KL
Sbjct: 181 IPYQPMPASSPVICAGGQDRCSDAAGYPHATHDLEGPPLDAYSIQGQH-TISPLDLAKLN 239
Query: 218 QLSSHAVPFA--------------TPSVV---PGLDPGTQTSSQEFLVPNDLIGCVIGRQ 260
Q++ FA +P V LD TQT + E +PN+LIGC+IGRQ
Sbjct: 240 QVARQQSHFAMMHGGTGFAGIDSSSPEVKGYWASLDASTQT-THELTIPNNLIGCIIGRQ 298
Query: 261 GSKISEIRQMSGAHIKIGNQAEGAGERHVTITGSPVSIALAQYLITACLETAK 313
G+ I+EIRQMSGA IKI N EG+ R VTITGS SI+LAQYLI A L + K
Sbjct: 299 GANINEIRQMSGAQIKIANPVEGSSGRQVTITGSAASISLAQYLINARLSSEK 351
>gi|14165439 heterogeneous nuclear ribonucleoprotein K isoform a
[Homo sapiens]
Length = 464
Score = 99.8 bits (247), Expect = 4e-21
Identities = 59/185 (31%), Positives = 93/185 (50%), Gaps = 20/185 (10%)
Query: 20 LRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSCPERITTITGSTAAVFHAVSMI 79
LR+L+ K G++IGK G+ +K +R +A +++ + S PERI +I+ + + I
Sbjct: 45 LRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKI 104
Query: 80 AFKLDEDLCAAPANGGNVSRP-------------------PVTLRLVIPASQCGSLIGKA 120
L+E L P+ P LRL+I S G +IG
Sbjct: 105 IPTLEEGL-QLPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGVK 163
Query: 121 GTKIKEIRETTGAQVQVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVILESPPKGATI 180
G KIKE+RE T +++ + P+ST+R V + G PD ++ C++ I +I ESP KG
Sbjct: 164 GAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRVVECIKIILDLISESPIKGRAQ 223
Query: 181 PYHPS 185
PY P+
Sbjct: 224 PYDPN 228
Score = 58.5 bits (140), Expect = 1e-08
Identities = 30/70 (42%), Positives = 42/70 (60%)
Query: 236 DPGTQTSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAEGAGERHVTITGSP 295
D G + + +P DL G +IG+ G +I +IR SGA IKI EG+ +R +TITG+
Sbjct: 382 DLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQ 441
Query: 296 VSIALAQYLI 305
I AQYL+
Sbjct: 442 DQIQNAQYLL 451
Score = 51.6 bits (122), Expect = 1e-06
Identities = 24/65 (36%), Positives = 41/65 (63%), Gaps = 1/65 (1%)
Query: 95 GNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPNSTERAVTVSG 154
G++ P +T ++ IP GS+IGK G +IK+IR +GA +++ + L S +R +T++G
Sbjct: 381 GDLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKI-DEPLEGSEDRIITITG 439
Query: 155 VPDAI 159
D I
Sbjct: 440 TQDQI 444
Score = 41.2 bits (95), Expect = 0.002
Identities = 49/195 (25%), Positives = 80/195 (41%), Gaps = 39/195 (20%)
Query: 102 VTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPNSTERAVTVSGVPDAIIL 161
V LR+++ + G++IGK G IK +R A V V P ER +++S A I
Sbjct: 43 VELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGP---ERILSIS----ADIE 95
Query: 162 CVRQICAVILESPPKGATIPYHPSLSLGTVLLSANQGFSVQGQYGAVTPAEVTKLQQLSS 221
+ +I I+ + +G +P +P ++L L S
Sbjct: 96 TIGEILKKIIPTLEEGLQLP---------------------------SPTATSQL-PLES 127
Query: 222 HAVPFATPSVVPGLDPGTQTSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQ- 280
AV G D + L+ L G +IG +G+KI E+R+ + IK+ +
Sbjct: 128 DAVECLNYQHYKGSDFDCEL---RLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQEC 184
Query: 281 AEGAGERHVTITGSP 295
+ +R V I G P
Sbjct: 185 CPHSTDRVVLIGGKP 199
Score = 38.5 bits (88), Expect = 0.011
Identities = 22/48 (45%), Positives = 30/48 (62%), Gaps = 2/48 (4%)
Query: 30 GSIIGKKGETVKRIREQSSARITISE--GSCPERITTITGSTAAVFHA 75
GSIIGK G+ +K+IR +S A I I E +RI TITG+ + +A
Sbjct: 400 GSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNA 447
>gi|14165435 heterogeneous nuclear ribonucleoprotein K isoform b
[Homo sapiens]
Length = 463
Score = 99.8 bits (247), Expect = 4e-21
Identities = 59/185 (31%), Positives = 93/185 (50%), Gaps = 20/185 (10%)
Query: 20 LRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSCPERITTITGSTAAVFHAVSMI 79
LR+L+ K G++IGK G+ +K +R +A +++ + S PERI +I+ + + I
Sbjct: 45 LRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKI 104
Query: 80 AFKLDEDLCAAPANGGNVSRP-------------------PVTLRLVIPASQCGSLIGKA 120
L+E L P+ P LRL+I S G +IG
Sbjct: 105 IPTLEEGL-QLPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGVK 163
Query: 121 GTKIKEIRETTGAQVQVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVILESPPKGATI 180
G KIKE+RE T +++ + P+ST+R V + G PD ++ C++ I +I ESP KG
Sbjct: 164 GAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRVVECIKIILDLISESPIKGRAQ 223
Query: 181 PYHPS 185
PY P+
Sbjct: 224 PYDPN 228
Score = 58.5 bits (140), Expect = 1e-08
Identities = 30/70 (42%), Positives = 42/70 (60%)
Query: 236 DPGTQTSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAEGAGERHVTITGSP 295
D G + + +P DL G +IG+ G +I +IR SGA IKI EG+ +R +TITG+
Sbjct: 382 DLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQ 441
Query: 296 VSIALAQYLI 305
I AQYL+
Sbjct: 442 DQIQNAQYLL 451
Score = 51.6 bits (122), Expect = 1e-06
Identities = 24/65 (36%), Positives = 41/65 (63%), Gaps = 1/65 (1%)
Query: 95 GNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPNSTERAVTVSG 154
G++ P +T ++ IP GS+IGK G +IK+IR +GA +++ + L S +R +T++G
Sbjct: 381 GDLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKI-DEPLEGSEDRIITITG 439
Query: 155 VPDAI 159
D I
Sbjct: 440 TQDQI 444
Score = 41.2 bits (95), Expect = 0.002
Identities = 49/195 (25%), Positives = 80/195 (41%), Gaps = 39/195 (20%)
Query: 102 VTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPNSTERAVTVSGVPDAIIL 161
V LR+++ + G++IGK G IK +R A V V P ER +++S A I
Sbjct: 43 VELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGP---ERILSIS----ADIE 95
Query: 162 CVRQICAVILESPPKGATIPYHPSLSLGTVLLSANQGFSVQGQYGAVTPAEVTKLQQLSS 221
+ +I I+ + +G +P +P ++L L S
Sbjct: 96 TIGEILKKIIPTLEEGLQLP---------------------------SPTATSQL-PLES 127
Query: 222 HAVPFATPSVVPGLDPGTQTSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQ- 280
AV G D + L+ L G +IG +G+KI E+R+ + IK+ +
Sbjct: 128 DAVECLNYQHYKGSDFDCEL---RLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQEC 184
Query: 281 AEGAGERHVTITGSP 295
+ +R V I G P
Sbjct: 185 CPHSTDRVVLIGGKP 199
Score = 38.5 bits (88), Expect = 0.011
Identities = 22/48 (45%), Positives = 30/48 (62%), Gaps = 2/48 (4%)
Query: 30 GSIIGKKGETVKRIREQSSARITISE--GSCPERITTITGSTAAVFHA 75
GSIIGK G+ +K+IR +S A I I E +RI TITG+ + +A
Sbjct: 400 GSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNA 447
>gi|14165437 heterogeneous nuclear ribonucleoprotein K isoform a
[Homo sapiens]
Length = 464
Score = 99.8 bits (247), Expect = 4e-21
Identities = 59/185 (31%), Positives = 93/185 (50%), Gaps = 20/185 (10%)
Query: 20 LRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSCPERITTITGSTAAVFHAVSMI 79
LR+L+ K G++IGK G+ +K +R +A +++ + S PERI +I+ + + I
Sbjct: 45 LRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKI 104
Query: 80 AFKLDEDLCAAPANGGNVSRP-------------------PVTLRLVIPASQCGSLIGKA 120
L+E L P+ P LRL+I S G +IG
Sbjct: 105 IPTLEEGL-QLPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGVK 163
Query: 121 GTKIKEIRETTGAQVQVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVILESPPKGATI 180
G KIKE+RE T +++ + P+ST+R V + G PD ++ C++ I +I ESP KG
Sbjct: 164 GAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRVVECIKIILDLISESPIKGRAQ 223
Query: 181 PYHPS 185
PY P+
Sbjct: 224 PYDPN 228
Score = 58.5 bits (140), Expect = 1e-08
Identities = 30/70 (42%), Positives = 42/70 (60%)
Query: 236 DPGTQTSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAEGAGERHVTITGSP 295
D G + + +P DL G +IG+ G +I +IR SGA IKI EG+ +R +TITG+
Sbjct: 382 DLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQ 441
Query: 296 VSIALAQYLI 305
I AQYL+
Sbjct: 442 DQIQNAQYLL 451
Score = 51.6 bits (122), Expect = 1e-06
Identities = 24/65 (36%), Positives = 41/65 (63%), Gaps = 1/65 (1%)
Query: 95 GNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPNSTERAVTVSG 154
G++ P +T ++ IP GS+IGK G +IK+IR +GA +++ + L S +R +T++G
Sbjct: 381 GDLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKI-DEPLEGSEDRIITITG 439
Query: 155 VPDAI 159
D I
Sbjct: 440 TQDQI 444
Score = 41.2 bits (95), Expect = 0.002
Identities = 49/195 (25%), Positives = 80/195 (41%), Gaps = 39/195 (20%)
Query: 102 VTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPNSTERAVTVSGVPDAIIL 161
V LR+++ + G++IGK G IK +R A V V P ER +++S A I
Sbjct: 43 VELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGP---ERILSIS----ADIE 95
Query: 162 CVRQICAVILESPPKGATIPYHPSLSLGTVLLSANQGFSVQGQYGAVTPAEVTKLQQLSS 221
+ +I I+ + +G +P +P ++L L S
Sbjct: 96 TIGEILKKIIPTLEEGLQLP---------------------------SPTATSQL-PLES 127
Query: 222 HAVPFATPSVVPGLDPGTQTSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQ- 280
AV G D + L+ L G +IG +G+KI E+R+ + IK+ +
Sbjct: 128 DAVECLNYQHYKGSDFDCEL---RLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQEC 184
Query: 281 AEGAGERHVTITGSP 295
+ +R V I G P
Sbjct: 185 CPHSTDRVVLIGGKP 199
Score = 38.5 bits (88), Expect = 0.011
Identities = 22/48 (45%), Positives = 30/48 (62%), Gaps = 2/48 (4%)
Query: 30 GSIIGKKGETVKRIREQSSARITISE--GSCPERITTITGSTAAVFHA 75
GSIIGK G+ +K+IR +S A I I E +RI TITG+ + +A
Sbjct: 400 GSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNA 447
>gi|17402900 far upstream element-binding protein [Homo sapiens]
Length = 644
Score = 84.3 bits (207), Expect = 2e-16
Identities = 101/408 (24%), Positives = 163/408 (39%), Gaps = 80/408 (19%)
Query: 29 VGSIIGKKGETVKRIREQSSARITIS--EGSCPERITTITGSTAAVFHAVSMIAFKLDED 86
VG IIG+ GE + RI+++S +I I+ G PER +TG+ +V A ++ +++
Sbjct: 112 VGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSAKRLLDQIVEK- 170
Query: 87 LCAAPANGGNVSRPP--VTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPN 144
PA G + P ++IPAS+ G +IGK G IK+++E G ++ + D N
Sbjct: 171 --GRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQN 228
Query: 145 S-TERAVTVSGVPDAIILCVRQICAVILE---------------SPPKGATIPYHPSLSL 188
+ ++ + ++G P + + +I + +G +P P ++
Sbjct: 229 TGADKPLRITGDPYKVQQAKEMVLELIRDQGGFREVRNEYGSRIGGNEGIDVPI-PRFAV 287
Query: 189 GTVL---------LSANQGFSVQGQ-YGAVTP---AEVTKLQQLSSHAVPFATP---SVV 232
G V+ + + G +Q + TP A++T HA T SV
Sbjct: 288 GIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPERIAQITGPPDRCQHAAEIITDLLRSVQ 347
Query: 233 PG--------------------LDPGTQTSSQEFLVPNDLIGCVIGRQGSKISEIRQMSG 272
G + P F+VP G +IG+ G I I Q SG
Sbjct: 348 AGNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSG 407
Query: 273 AHIKIGNQAEGAGERHV---TITGSPVSIALAQYLITACLETAKSTSGGTPSSAPADLPA 329
A I++ + ++ TI G+P I A+ LI + + G P +P
Sbjct: 408 ARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLGPPVPHGPHGVPG 467
Query: 330 PFSPPLTALPTAPPGLLGTPYAISLSNFIGLKPMPFLALPPASPGPPP 377
P PP PPG GTP P P+ P PGP P
Sbjct: 468 PHGPP------GPPG-PGTPMG-------PYNPAPY---NPGPPGPAP 498
Score = 57.0 bits (136), Expect = 3e-08
Identities = 37/138 (26%), Positives = 64/138 (46%), Gaps = 2/138 (1%)
Query: 189 GTVLLSANQGFSVQGQYGAVTPAEVTKLQQLSSHAVPFATPSVVPGLDPGTQTSSQEFLV 248
GT L S + G+ GQ + + ++++ F T ++E+ V
Sbjct: 50 GTSLNSNDYGYG--GQKRPLEDGDQPDAKKVAPQNDSFGTQLPPMHQQQSRSVMTEEYKV 107
Query: 249 PNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAEGAGERHVTITGSPVSIALAQYLITAC 308
P+ ++G +IGR G +IS I+Q SG I+I + G ER +TG+P S+ A+ L+
Sbjct: 108 PDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSAKRLLDQI 167
Query: 309 LETAKSTSGGTPSSAPAD 326
+E + G P +
Sbjct: 168 VEKGRPAPGFHHGDGPGN 185
Score = 51.6 bits (122), Expect = 1e-06
Identities = 60/263 (22%), Positives = 107/263 (40%), Gaps = 45/263 (17%)
Query: 98 SRPPVTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDL--LPNSTERAVTVSGV 155
SR +T +P G +IG+ G +I I++ +G ++Q+A D LP ER+ ++G
Sbjct: 97 SRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLP---ERSCMLTGT 153
Query: 156 PDAIILCVRQICAVILES-PPKGATIPYHPSLSLGTVLLSANQGFSVQGQ---------- 204
P+++ R + ++ + P G P ++ +++ A++ V G+
Sbjct: 154 PESVQSAKRLLDQIVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQE 213
Query: 205 ---------------YGAVTPAEVT----KLQQLSSHAVPFATPSVVPGL-----DPGTQ 240
GA P +T K+QQ + G + G++
Sbjct: 214 RAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQAKEMVLELIRDQ--GGFREVRNEYGSR 271
Query: 241 TSSQEFL---VPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAEGAGERHVTITGSPVS 297
E + +P +G VIGR G I +I+ +G I+ ER ITG P
Sbjct: 272 IGGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPERIAQITGPPDR 331
Query: 298 IALAQYLITACLETAKSTSGGTP 320
A +IT L + ++ + G P
Sbjct: 332 CQHAAEIITDLLRSVQAGNPGGP 354
Score = 39.3 bits (90), Expect = 0.006
Identities = 27/86 (31%), Positives = 41/86 (47%), Gaps = 14/86 (16%)
Query: 3 GSDGGLEEEPELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSCPE-- 60
G GGL+E ++ + G IIGK GET+K I +QS ARI + P
Sbjct: 371 GPPGGLQE---------FNFIVPTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPNAD 421
Query: 61 ---RITTITGSTAAVFHAVSMIAFKL 83
++ TI G+ + +A +I K+
Sbjct: 422 PNMKLFTIRGTPQQIDYARQLIEEKI 447
>gi|154355000 KH-type splicing regulatory protein [Homo sapiens]
Length = 711
Score = 82.4 bits (202), Expect = 7e-16
Identities = 103/417 (24%), Positives = 160/417 (38%), Gaps = 76/417 (18%)
Query: 1 MSGSDGGLEEEPELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITIS--EGSC 58
+S G + P S+T R+ VG IIG+ GE + +I++ S ++ IS G
Sbjct: 130 ISSQLGPIHPPPRTSMTEEYRV--PDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGL 187
Query: 59 PERITTITGSTAAVFHAVSMIAFKLDEDLCAAP------ANGGNVSRPPVTLRLVIPASQ 112
PER ++TG+ +V A M+ + P ANGG ++IPA +
Sbjct: 188 PERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNG---TVQEIMIPAGK 244
Query: 113 CGSLIGKAGTKIKEIRETTGAQVQVAGDLLPN-STERAVTVSGVPDAIILCVRQICAVIL 171
G +IGK G IK+++E G ++ + D N + ++ + + G P + + ++
Sbjct: 245 AGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACEMVMDILR 304
Query: 172 ESPPKG----------------ATIPYHPSLSLGTVL---------LSANQGFSVQ-GQY 205
E G +P H S+G V+ + + G +Q Q
Sbjct: 305 ERDQGGFGDRNEYGSRIGGGIDVPVPRH---SVGVVIGRSGEMIKKIQNDAGVRIQFKQD 361
Query: 206 GAVTPAEVTKLQ---QLSSHAVPFAT------------PSVVPGLDPGTQ---------- 240
P ++ + HA P PG+ PG +
Sbjct: 362 DGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMPPGGRGRGRGQGNWG 421
Query: 241 --TSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAEGAGE---RHVTITGSP 295
F +P G VIGR G + I Q +GA ++I Q G+ + I GSP
Sbjct: 422 PPGGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSP 481
Query: 296 VSIALAQYLITACLETAKSTSGGTPSS-APADLPAPFSP-PLT-ALPTAPPGLLGTP 349
I A+ LI +E G P PA PF+P P P APP G P
Sbjct: 482 QQIDHAKQLIEEKIEGPLCPVGPGPGGPGPAGPMGPFNPGPFNQGPPGAPPHAGGPP 538
Score = 57.0 bits (136), Expect = 3e-08
Identities = 34/131 (25%), Positives = 70/131 (53%), Gaps = 4/131 (3%)
Query: 190 TVLLSANQGFSVQGQYGAVTPAEVTKLQQLSSHAVPFATPSVVPGLDPGTQTSSQEFLVP 249
T + ++ F GQ + + + ++L+S ++ + P P + ++E+ VP
Sbjct: 94 TTVNNSTPDFGFGGQKRQLEDGDQPESKKLASQGDSISS-QLGPIHPPPRTSMTEEYRVP 152
Query: 250 NDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAEGAGERHVTITGSPVSIALAQYLITACL 309
+ ++G +IGR G +I++I+Q SG ++I + G ER V++TG+P S+ A+ ++ +
Sbjct: 153 DGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIV 212
Query: 310 ETAKSTSGGTP 320
+ GG P
Sbjct: 213 SRGR---GGPP 220
Score = 28.9 bits (63), Expect = 8.6
Identities = 16/58 (27%), Positives = 21/58 (36%), Gaps = 5/58 (8%)
Query: 320 PSSAPADLPAPFSPPLTALPTAPPGLLGTPYAISLSNFIGLKPMPFLALPPASPGPPP 377
P P PAP +PP P PP + Y + + + P PG PP
Sbjct: 588 PGPVPGPAPAPAAPPAQGEPPQPPPTGQSDYTKAWEEY-----YKKIGQQPQQPGAPP 640
>gi|5902724 neuro-oncological ventral antigen 2 [Homo sapiens]
Length = 492
Score = 80.5 bits (197), Expect = 3e-15
Identities = 91/347 (26%), Positives = 140/347 (40%), Gaps = 67/347 (19%)
Query: 21 RMLMHGKEVGSIIGKKGETVKRIREQSSARITISEG----SCPERITTITGSTAAVFHAV 76
++++ G IIGK G TVK + EQS A + +S+ + ER+ T++G V AV
Sbjct: 134 KLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPEGINLQERVVTVSGEPEQVHKAV 193
Query: 77 SMIAFKLDED-------------LCAAPANGGNVSRPPVTLRLVIPASQCGS------LI 117
S I K+ ED + AN P + V+PA+ S L+
Sbjct: 194 SAIVQKVQEDPQSSSCLNISYANVAGPVANSNPTGSPYASPADVLPAAAAASAAAASGLL 253
Query: 118 GKAGTKIKEIRETTGAQVQVAG-DLLPNSTERAVTVSGVPDAIILCVRQICAV---ILES 173
G AG + + A +G DLL ST S + L + A +L +
Sbjct: 254 GPAG--LAGVGAFPAALPAFSGTDLLAISTALNTLASYGYNTNSLGLGLNSAAASGVLAA 311
Query: 174 PPKGATIPYHPSLSLGTVLLSANQGFSVQGQYGAVTPAEVTKLQQLSSHAV--------- 224
GA +P+ + LL++ G + G G P L S A+
Sbjct: 312 VAAGA----NPAAAAAANLLASYAGEAGAGPAGGAAPPPPPPPGALGSFALAAAANGYLG 367
Query: 225 ------------PFATPSVVPGLDPGTQTSSQ----------EFLVPNDLIGCVIGRQGS 262
P + G G T+ + E VP +L+G ++G+ G
Sbjct: 368 AGAGGGAGGGGGPLVAAAAAAGAAGGFLTAEKLAAESAKELVEIAVPENLVGAILGKGGK 427
Query: 263 KISEIRQMSGAHIKIGNQAE---GAGERHVTITGSPVSIALAQYLIT 306
+ E ++++GA I+I + E G R VTITGSP + AQYLI+
Sbjct: 428 TLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAATQAAQYLIS 474
Score = 77.8 bits (190), Expect = 2e-14
Identities = 100/405 (24%), Positives = 159/405 (39%), Gaps = 67/405 (16%)
Query: 20 LRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGS-----CPERITTITGSTAAVFH 74
L++L+ GSIIGK G+T+ ++++++ A I +S+ ER+ + G+ A+
Sbjct: 35 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLVQGTAEALNA 94
Query: 75 AVSMIAFKLDE-DLCAAPANGGNVSRPPVTL--------RLVIPASQCGSLIGKAGTKIK 125
S IA K+ E N+ +P T+ +L++P S G +IGK G +K
Sbjct: 95 VHSFIAEKVREIPQAMTKPEVVNILQPQTTMNPDRAKQAKLIVPNSTAGLIIGKGGATVK 154
Query: 126 EIRETTGAQVQVAGDLLP---NSTERAVTVSGVPDAIILCVRQICAVILESPPKGATIPY 182
+ E +GA VQ++ P N ER VTVSG P+ + V I + E P + +
Sbjct: 155 AVMEQSGAWVQLSQK--PEGINLQERVVTVSGEPEQVHKAVSAIVQKVQEDPQSSSCL-- 210
Query: 183 HPSLSLGTVLLSANQGFSVQGQYGAVTPAEVTKLQQLSSHAVPFATPS-VVPGLDPGTQT 241
S G V + T P+A+P+ V+P +
Sbjct: 211 ---------------NISYANVAGPVANSNPT--------GSPYASPADVLPAAAAASAA 247
Query: 242 SSQEFLVPNDLIG------CVIGRQGSKISEIRQMSGAHIKIG--NQAEGAGERHVTITG 293
++ L P L G + G+ + I G + G G +G
Sbjct: 248 AASGLLGPAGLAGVGAFPAALPAFSGTDLLAISTALNTLASYGYNTNSLGLGLNSAAASG 307
Query: 294 SPVSIALAQYLITACLETAKSTSGGTPSSAPADLPAPFSPPLTALPTAPPGLLGT-PYAI 352
++A A ++ G + PA AP PP PPG LG+ A
Sbjct: 308 VLAAVAAGANPAAAAAANLLASYAGEAGAGPAGGAAPPPPP-------PPGALGSFALAA 360
Query: 353 SLSNFIGLKPMPFLALPPASPGPPPGLAAYTAKMAAANGSKKAER 397
+ + ++G A A G P L A A AA G AE+
Sbjct: 361 AANGYLGAG-----AGGGAGGGGGP-LVAAAAAAGAAGGFLTAEK 399
>gi|64085377 insulin-like growth factor 2 mRNA binding protein 2
isoform a [Homo sapiens]
Length = 599
Score = 76.6 bits (187), Expect = 4e-14
Identities = 83/309 (26%), Positives = 135/309 (43%), Gaps = 33/309 (10%)
Query: 16 ITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITI----SEGSCPERIT---TITGS 68
I LR+L+ + VG+IIGK+G T+K I +Q+ +R+ I + G+ + +T T G+
Sbjct: 192 IDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGT 251
Query: 69 TAAVFHAVSMIAFKLDEDLCAAPANGGNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIR 128
+ A + ++ + DE A + L+++ G LIGK G +K+I
Sbjct: 252 SEACRMILEIMQKEADETKLA----------EEIPLKILAHNGLVGRLIGKEGRNLKKIE 301
Query: 129 ETTGAQVQVAG--DLLPNSTERAVTVSGVPDAIILCVRQICAVILESPPKGATIPYHPSL 186
TG ++ ++ DL + ER +TV G +A +I + E+ +
Sbjct: 302 HETGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREAFENDMLAVNQQAN 361
Query: 187 SLGTVLLSA----NQGFSV----QGQYGAVTPA---EVTKLQQLSSHAVPFATPSVVPGL 235
+ + LSA + G SV G GA A T S P P
Sbjct: 362 LIPGLNLSALGIFSTGLSVLSPPAGPRGAPPAAPYHPFTTHSGYFSSLYPHHQFGPFPHH 421
Query: 236 DPGTQTSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAEG--AGERHVTITG 293
+ +P +G +IG++G+ I ++ + +GA IKI AEG ER V ITG
Sbjct: 422 HSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIA-PAEGPDVSERMVIITG 480
Query: 294 SPVSIALAQ 302
P + AQ
Sbjct: 481 PPEAQFKAQ 489
Score = 61.2 bits (147), Expect = 2e-09
Identities = 41/125 (32%), Positives = 60/125 (48%), Gaps = 8/125 (6%)
Query: 29 VGSIIGKKGETVKRIREQSSARITISEGSCP---ERITTITGSTAAVFHAVSMIAFKLDE 85
VG+IIGKKG +K++ + A I I+ P ER+ ITG A F A I KL E
Sbjct: 439 VGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQGRIFGKLKE 498
Query: 86 DLCAAPANGGNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPNS 145
+ P + + +P+S G +IGK G + E++ T A+V V D P+
Sbjct: 499 ENFFNPKE-----EVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDE 553
Query: 146 TERAV 150
E +
Sbjct: 554 NEEVI 558
Score = 44.7 bits (104), Expect = 2e-04
Identities = 28/81 (34%), Positives = 43/81 (53%), Gaps = 5/81 (6%)
Query: 10 EEPELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGS-----CPERITT 64
+E +L+ + L++L H VG +IGK+G +K+I ++ +ITIS PER T
Sbjct: 267 DETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTIT 326
Query: 65 ITGSTAAVFHAVSMIAFKLDE 85
+ G+ A A I KL E
Sbjct: 327 VKGTVEACASAEIEIMKKLRE 347
Score = 44.7 bits (104), Expect = 2e-04
Identities = 33/117 (28%), Positives = 56/117 (47%), Gaps = 10/117 (8%)
Query: 104 LRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPNSTERAVTVSGVPDAIILCV 163
+ L IP G++IGK G IK++ GA +++A P+ +ER V ++G P+A
Sbjct: 430 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQ 489
Query: 164 RQICAVILE----SPPKGATIPYH---PSLSLGTVLLSANQGFSVQGQYGAVTPAEV 213
+I + E +P + + H PS + G V+ +G + +T AEV
Sbjct: 490 GRIFGKLKEENFFNPKEEVKLEAHIRVPSSTAGRVI---GKGGKTVNELQNLTSAEV 543
Score = 43.5 bits (101), Expect = 3e-04
Identities = 49/226 (21%), Positives = 84/226 (37%), Gaps = 62/226 (27%)
Query: 90 APANGGNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPNSTERA 149
AP + LR+++P G++IGK G IK I + T ++V + + E+
Sbjct: 182 APGGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKP 241
Query: 150 VTVSGVPDAIILCVRQICAVILESPPKGATIPYHPSLSLGTVLLSANQGFSVQGQYGAVT 209
VT+ P+ + C +ILE K
Sbjct: 242 VTIHATPEG----TSEACRMILEIMQK--------------------------------- 264
Query: 210 PAEVTKLQQLSSHAVPFATPSVVPGLDPGTQTSSQEFLVPNDLIGCVIGRQGSKISEIRQ 269
A+ TKL + +P + L N L+G +IG++G + +I
Sbjct: 265 EADETKL----AEEIPL------------------KILAHNGLVGRLIGKEGRNLKKIEH 302
Query: 270 MSGAHIKIGNQAEGA---GERHVTITGSPVSIALAQYLITACLETA 312
+G I I + + + ER +T+ G+ + A A+ I L A
Sbjct: 303 ETGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREA 348
Score = 30.8 bits (68), Expect = 2.3
Identities = 16/59 (27%), Positives = 29/59 (49%), Gaps = 4/59 (6%)
Query: 6 GGLEEE----PELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSCPE 60
G L+EE P+ + L + + G +IGK G+TV ++ +SA + + P+
Sbjct: 494 GKLKEENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPD 552
>gi|56549653 neuro-oncological ventral antigen 1 isoform 1 [Homo
sapiens]
Length = 507
Score = 75.9 bits (185), Expect = 6e-14
Identities = 77/332 (23%), Positives = 132/332 (39%), Gaps = 33/332 (9%)
Query: 20 LRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEG----SCPERITTITGSTAAVFHA 75
+++++ G IIGK G TVK + EQS A + +S+ + ER+ T++G A
Sbjct: 174 VKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKA 233
Query: 76 VSMIAFKLDED-------------LCAAPANGGNVSRPPVTLRLVIP-ASQCGSLIGKAG 121
V +I K+ ED + AN P V+P A+ L+G A
Sbjct: 234 VELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHAN 293
Query: 122 TKIKEIRETTGAQVQVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVILESPPKGATIP 181
+ + G+ L T T++ + + A
Sbjct: 294 --LAGVAAFPAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAAS 351
Query: 182 YHPSLSLGTVLLS-----ANQGFSVQGQYGAVTPAEVTKLQQLSSHAVPFATP---SVVP 233
+P+ + +L + + G + G G + ++ A+P S +
Sbjct: 352 ANPAAAAANLLATYASEASASGSTAGGTAGTFALGSLAAATAATNGYFGAASPLAASAIL 411
Query: 234 GLDPGTQTSSQ--EFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAE---GAGERH 288
G + T S E VP +L+G ++G+ G + E ++++GA I+I + E G R
Sbjct: 412 GTEKSTDGSKDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRK 471
Query: 289 VTITGSPVSIALAQYLITACLETAKSTSGGTP 320
VTITG+P + AQYLIT + + P
Sbjct: 472 VTITGTPAATQAAQYLITQRITYEQGVRAANP 503
Score = 72.8 bits (177), Expect = 5e-13
Identities = 69/263 (26%), Positives = 118/263 (44%), Gaps = 43/263 (16%)
Query: 104 LRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAG--DLLPNSTERAVTVSGVPDAIIL 161
L+++IP+ GS+IGK G I ++++ TGA ++++ D P +TER + G +A+
Sbjct: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
Query: 162 CVRQICAVILESPPKGATIPYHPSLSLGTVLLSANQGFSVQGQYGAVTPAEVTKLQQLSS 221
I I E P ++ + S+ V P + K SS
Sbjct: 112 VHGFIAEKIREMPQN----------------VAKTEPVSILQPQTTVNPDRI-KQTLPSS 154
Query: 222 HAVPFATPSVVPGLDPGTQTSSQE--FLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGN 279
++PS DP T + + + +VPN G +IG+ G+ + + + SGA +++
Sbjct: 155 PTTTKSSPS-----DPMTTSRANQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQ 209
Query: 280 QAEGAG--ERHVTITGSPVSIALAQYLIT----------ACLETA-KSTSGGTPSSAPAD 326
+ +G ER VT++G P A LI +CL + + +G +S P
Sbjct: 210 KPDGINLQERVVTVSGEPEQNRKAVELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTG 269
Query: 327 LPAPFSPPLTALPT--APPGLLG 347
+P++ LPT A GLLG
Sbjct: 270 --SPYANTAEVLPTAAAAAGLLG 290
Score = 63.9 bits (154), Expect = 2e-10
Identities = 55/201 (27%), Positives = 91/201 (45%), Gaps = 41/201 (20%)
Query: 20 LRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEG-----SCPERITTITGSTAAVFH 74
L++L+ GSIIGK G+T+ ++++++ A I +S+ ER+ I G+ A+
Sbjct: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
Query: 75 AVSMIAFKLDE---------------------------DLCAAPANGGNVSRPPVT---- 103
IA K+ E L ++P + P+T
Sbjct: 112 VHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQTLPSSPTTTKSSPSDPMTTSRA 171
Query: 104 --LRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVA--GDLLPNSTERAVTVSGVPDAI 159
+++++P S G +IGK G +K + E +GA VQ++ D + N ER VTVSG P+
Sbjct: 172 NQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGI-NLQERVVTVSGEPEQN 230
Query: 160 ILCVRQICAVILESPPKGATI 180
V I I E P G+ +
Sbjct: 231 RKAVELIIQKIQEDPQSGSCL 251
>gi|56549651 neuro-oncological ventral antigen 1 isoform 2 [Homo
sapiens]
Length = 483
Score = 75.9 bits (185), Expect = 6e-14
Identities = 77/332 (23%), Positives = 132/332 (39%), Gaps = 33/332 (9%)
Query: 20 LRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEG----SCPERITTITGSTAAVFHA 75
+++++ G IIGK G TVK + EQS A + +S+ + ER+ T++G A
Sbjct: 150 VKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKA 209
Query: 76 VSMIAFKLDED-------------LCAAPANGGNVSRPPVTLRLVIP-ASQCGSLIGKAG 121
V +I K+ ED + AN P V+P A+ L+G A
Sbjct: 210 VELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHAN 269
Query: 122 TKIKEIRETTGAQVQVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVILESPPKGATIP 181
+ + G+ L T T++ + + A
Sbjct: 270 --LAGVAAFPAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAAS 327
Query: 182 YHPSLSLGTVLLS-----ANQGFSVQGQYGAVTPAEVTKLQQLSSHAVPFATP---SVVP 233
+P+ + +L + + G + G G + ++ A+P S +
Sbjct: 328 ANPAAAAANLLATYASEASASGSTAGGTAGTFALGSLAAATAATNGYFGAASPLAASAIL 387
Query: 234 GLDPGTQTSSQ--EFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAE---GAGERH 288
G + T S E VP +L+G ++G+ G + E ++++GA I+I + E G R
Sbjct: 388 GTEKSTDGSKDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRK 447
Query: 289 VTITGSPVSIALAQYLITACLETAKSTSGGTP 320
VTITG+P + AQYLIT + + P
Sbjct: 448 VTITGTPAATQAAQYLITQRITYEQGVRAANP 479
Score = 70.1 bits (170), Expect = 3e-12
Identities = 54/177 (30%), Positives = 89/177 (50%), Gaps = 17/177 (9%)
Query: 20 LRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGS-----CPERITTITGSTAAVFH 74
L++L+ GSIIGK G+T+ ++++++ A I +S+ ER+ I G+ A+
Sbjct: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
Query: 75 AVSMIAFKLDE-DLCAAPANGGNVSRPPVTL--------RLVIPASQCGSLIGKAGTKIK 125
IA K+ E A ++ +P T+ ++++P S G +IGK G +K
Sbjct: 112 VHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVK 171
Query: 126 EIRETTGAQVQVA--GDLLPNSTERAVTVSGVPDAIILCVRQICAVILESPPKGATI 180
+ E +GA VQ++ D + N ER VTVSG P+ V I I E P G+ +
Sbjct: 172 AVMEQSGAWVQLSQKPDGI-NLQERVVTVSGEPEQNRKAVELIIQKIQEDPQSGSCL 227
Score = 63.2 bits (152), Expect = 4e-10
Identities = 61/261 (23%), Positives = 108/261 (41%), Gaps = 63/261 (24%)
Query: 104 LRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAG--DLLPNSTERAVTVSGVPDAIIL 161
L+++IP+ GS+IGK G I ++++ TGA ++++ D P +TER + G +A+
Sbjct: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
Query: 162 CVRQICAVILESPPKGATIPYHPSLSLGTVLLSANQGFSVQGQYGAVTPAEVTKLQQLSS 221
I I E P ++ + S+ V P + +++
Sbjct: 112 VHGFIAEKIREMPQN----------------VAKTEPVSILQPQTTVNPDRIKQVK---- 151
Query: 222 HAVPFATPSVVPGLDPGTQTSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQA 281
+VPN G +IG+ G+ + + + SGA +++ +
Sbjct: 152 ------------------------IIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKP 187
Query: 282 EGAG--ERHVTITGSPVSIALAQYLIT----------ACLETA-KSTSGGTPSSAPADLP 328
+G ER VT++G P A LI +CL + + +G +S P
Sbjct: 188 DGINLQERVVTVSGEPEQNRKAVELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTG-- 245
Query: 329 APFSPPLTALPT--APPGLLG 347
+P++ LPT A GLLG
Sbjct: 246 SPYANTAEVLPTAAAAAGLLG 266
>gi|30795212 insulin-like growth factor 2 mRNA binding protein 3
[Homo sapiens]
Length = 579
Score = 74.7 bits (182), Expect = 1e-13
Identities = 77/309 (24%), Positives = 139/309 (44%), Gaps = 33/309 (10%)
Query: 3 GSDGGLEEEPELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITI----SEGSC 58
GS G + ++ L LR+L+ + VG+IIGK+G T++ I +Q+ ++I + + G+
Sbjct: 183 GSPGSVSKQKPCD--LPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAA 240
Query: 59 PERITTIT--GSTAAVFHAVSMIAFKLDEDLCAAPANGGNVSRPPVTLRLVIPASQCGSL 116
+ IT ++ T+A ++ I K +D+ + L+++ + G L
Sbjct: 241 EKSITILSTPEGTSAACKSILEIMHKEAQDI---------KFTEEIPLKILAHNNFVGRL 291
Query: 117 IGKAGTKIKEIRETTGAQVQVA--GDLLPNSTERAVTVSGVPDAIILCVRQICAVILESP 174
IGK G +K+I + T ++ ++ +L + ER +TV G + +I I ES
Sbjct: 292 IGKEGRNLKKIEQDTDTKITISPLQELTLYNPERTITVKGNVETCAKAEEEIMKKIRES- 350
Query: 175 PKGATIPYHPSLSLGTVLLSANQGFSVQGQYGAVTPAEVTKLQQLSSHAVPFATPSVVPG 234
Y ++ + G ++ G P T + P A P
Sbjct: 351 -------YENDIASMNLQAHLIPGLNLNA-LGLFPP---TSGMPPPTSGPPSAMTPPYPQ 399
Query: 235 LDPGTQTSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIG-NQAEGAGERHVTITG 293
+ ++T + +P +G +IG+QG I ++ + +GA IKI +A A R V ITG
Sbjct: 400 FEQ-SETETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVIITG 458
Query: 294 SPVSIALAQ 302
P + AQ
Sbjct: 459 PPEAQFKAQ 467
Score = 63.9 bits (154), Expect = 2e-10
Identities = 61/227 (26%), Positives = 92/227 (40%), Gaps = 52/227 (22%)
Query: 18 LTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGS-----CPERITTITGSTAAV 72
+ L++L H VG +IGK+G +K+I + + +ITIS PER T+ G+
Sbjct: 277 IPLKILAHNNFVGRLIGKEGRNLKKIEQDTDTKITISPLQELTLYNPERTITVKGNVETC 336
Query: 73 FHAVSMIAFKLDED----------------------LCAAPANGGN---VSRPPV----- 102
A I K+ E L P G S PP
Sbjct: 337 AKAEEEIMKKIRESYENDIASMNLQAHLIPGLNLNALGLFPPTSGMPPPTSGPPSAMTPP 396
Query: 103 ----------TLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPNSTERAVTV 152
T+ L IPA G++IGK G IK++ GA +++A P++ R V +
Sbjct: 397 YPQFEQSETETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVII 456
Query: 153 SGVPDAIILCVRQICAVILE----SPPKGATIPYH---PSLSLGTVL 192
+G P+A +I I E SP + + H PS + G V+
Sbjct: 457 TGPPEAQFKAQGRIYGKIKEENFVSPKEEVKLEAHIRVPSFAAGRVI 503
Score = 62.4 bits (150), Expect = 7e-10
Identities = 40/141 (28%), Positives = 69/141 (48%), Gaps = 8/141 (5%)
Query: 13 ELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSCPE---RITTITGST 69
E S T T+ + + VG+IIGK+G+ +K++ + A I I+ P+ R+ ITG
Sbjct: 401 EQSETETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVIITGPP 460
Query: 70 AAVFHAVSMIAFKLDEDLCAAPANGGNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRE 129
A F A I K+ E+ +P + + +P+ G +IGK G + E++
Sbjct: 461 EAQFKAQGRIYGKIKEENFVSPKE-----EVKLEAHIRVPSFAAGRVIGKGGKTVNELQN 515
Query: 130 TTGAQVQVAGDLLPNSTERAV 150
+ A+V V D P+ ++ V
Sbjct: 516 LSSAEVVVPRDQTPDENDQVV 536
Score = 34.7 bits (78), Expect = 0.16
Identities = 21/86 (24%), Positives = 38/86 (44%), Gaps = 4/86 (4%)
Query: 6 GGLEEE----PELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSCPER 61
G ++EE P+ + L + + G +IGK G+TV ++ SSA + + P+
Sbjct: 472 GKIKEENFVSPKEEVKLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQTPDE 531
Query: 62 ITTITGSTAAVFHAVSMIAFKLDEDL 87
+ F+A + K+ E L
Sbjct: 532 NDQVVVKITGHFYACQVAQRKIQEIL 557
>gi|100816392 far upstream element (FUSE) binding protein 3 [Homo
sapiens]
Length = 572
Score = 73.2 bits (178), Expect = 4e-13
Identities = 85/333 (25%), Positives = 132/333 (39%), Gaps = 62/333 (18%)
Query: 22 MLMHGKEVGSIIGKKGETVKRIREQSSAR-ITISEGSCP---ERITTITGSTAAVFHAVS 77
+L+ +VG +IG+ GET+K+++E++ + + I +G P ++ ITG V A
Sbjct: 167 ILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQARE 226
Query: 78 M---IAFKLDEDLCAAPANGGNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQ 134
M I + D+ N ++ + +P G +IG+ G IK+I+ G +
Sbjct: 227 MVLEIIREKDQADFRGVRGDFNSRMGGGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGVR 286
Query: 135 VQVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVILESPPKGATIPYHPSLSLGTVLLS 194
+Q D S ERA V G PD I +IL + + G + +
Sbjct: 287 IQFKPD-DGISPERAAQVMGPPDRCQHAAHIISELILTAQERD---------GFGGLAAA 336
Query: 195 ANQGFSVQGQYGAVTPAEVTKLQQLSSHAVPFATPSVVPGLDPGTQTSSQEFLVPNDLIG 254
+G +G + P V ++ + VP D G
Sbjct: 337 RGRGRG-RGDWSVGAPGGVQEI----------------------------TYTVPADKCG 367
Query: 255 CVIGRQGSKISEIRQMSGAHIKIGNQAEGAGE---RHVTITGSPVSIALAQYLITACLET 311
VIG+ G I I Q SGAH+++ + R TI G P I +A+ LI
Sbjct: 368 LVIGKGGENIKSINQQSGAHVELQRNPPPNSDPNLRRFTIRGVPQQIEVARQLI------ 421
Query: 312 AKSTSGGTPSSAPADL-PAPFSPPLTALPTAPP 343
GGT AP +PFS P APP
Sbjct: 422 -DEKVGGTNLGAPGAFGQSPFSQ-----PPAPP 448
Score = 65.1 bits (157), Expect = 1e-10
Identities = 69/297 (23%), Positives = 125/297 (42%), Gaps = 60/297 (20%)
Query: 27 KEVGSIIGKKGETVKRIREQSSARITISEGSC--PERITTITGSTAAVFHAVSMIAFKLD 84
K VG IIG+ GE + RI+ +S +I I+ S PER +TG+ ++ A ++ +D
Sbjct: 87 KMVGFIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIEQAKRLLGQIVD 146
Query: 85 EDLCA-APANGGNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQ-VQVAGDLL 142
C P ++ ++IPAS+ G +IG+ G IK+++E TG + V + L
Sbjct: 147 R--CRNGPGFHNDIDSNSTIQEILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPL 204
Query: 143 PNSTERAVTVSGVPDAIILCVRQICAVILESPPKGATIPYHPSLSLGTVLLSANQG--FS 200
P ++ + ++G DA V+Q ++LE ++ +Q
Sbjct: 205 PTGADKPLRITG--DA--FKVQQAREMVLE------------------IIREKDQADFRG 242
Query: 201 VQGQYGAVTPAEVTKLQQLSSHAVPFATPSVVPGLDPGTQTSSQEFLVPNDLIGCVIGRQ 260
V+G + + ++ ++ + P G+ VIGR
Sbjct: 243 VRGDFNS----------RMGGGSIEVSVPRFAVGI--------------------VIGRN 272
Query: 261 GSKISEIRQMSGAHIKIGNQAEGAGERHVTITGSPVSIALAQYLITACLETAKSTSG 317
G I +I+ +G I+ + ER + G P A ++I+ + TA+ G
Sbjct: 273 GEMIKKIQNDAGVRIQFKPDDGISPERAAQVMGPPDRCQHAAHIISELILTAQERDG 329
Score = 56.2 bits (134), Expect = 5e-08
Identities = 27/75 (36%), Positives = 47/75 (62%)
Query: 243 SQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAEGAGERHVTITGSPVSIALAQ 302
++EF VP+ ++G +IGR G +IS I+ SG I+I +++ G ER +TG+P SI A+
Sbjct: 79 TEEFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIEQAK 138
Query: 303 YLITACLETAKSTSG 317
L+ ++ ++ G
Sbjct: 139 RLLGQIVDRCRNGPG 153
>gi|56118219 insulin-like growth factor 2 mRNA binding protein 2
isoform b [Homo sapiens]
Length = 556
Score = 72.8 bits (177), Expect = 5e-13
Identities = 76/298 (25%), Positives = 130/298 (43%), Gaps = 54/298 (18%)
Query: 16 ITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITI----SEGSCPERIT---TITGS 68
I LR+L+ + VG+IIGK+G T+K I +Q+ +R+ I + G+ + +T T G+
Sbjct: 192 IDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGT 251
Query: 69 TAAVFHAVSMIAFKLDEDLCAAPANGGNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIR 128
+ A + ++ + DE A + L+++ G LIGK G +K+I
Sbjct: 252 SEACRMILEIMQKEADETKLA----------EEIPLKILAHNGLVGRLIGKEGRNLKKIE 301
Query: 129 ETTGAQVQVAG--DLLPNSTERAVTVSGVPDAIILCVRQICAVILESPPKGATIPYHPSL 186
TG ++ ++ DL + ER +TV G +A +I + E
Sbjct: 302 HETGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLRE-------------- 347
Query: 187 SLGTVLLSANQGFSVQGQYGAVTPAEVTKLQQLSSHAVPFATPSVVPGLDPGTQTSSQEF 246
+ +L+ N + G + ++ P PF P +
Sbjct: 348 AFENDMLAVN---THSGYFSSLYP---------HHQFGPFPHHHSYP------EQEIVNL 389
Query: 247 LVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAEG--AGERHVTITGSPVSIALAQ 302
+P +G +IG++G+ I ++ + +GA IKI AEG ER V ITG P + AQ
Sbjct: 390 FIPTQAVGAIIGKKGAHIKQLARFAGASIKIA-PAEGPDVSERMVIITGPPEAQFKAQ 446
Score = 72.4 bits (176), Expect = 7e-13
Identities = 65/237 (27%), Positives = 105/237 (44%), Gaps = 36/237 (15%)
Query: 10 EEPELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSC-----PERITT 64
+E +L+ + L++L H VG +IGK+G +K+I ++ +ITIS PER T
Sbjct: 267 DETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTIT 326
Query: 65 ITGSTAAVFHAVSMIAFKLDE----DLCAAPANGGNVSR-----------------PPVT 103
+ G+ A A I KL E D+ A + G S
Sbjct: 327 VKGTVEACASAEIEIMKKLREAFENDMLAVNTHSGYFSSLYPHHQFGPFPHHHSYPEQEI 386
Query: 104 LRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPNSTERAVTVSGVPDAIILCV 163
+ L IP G++IGK G IK++ GA +++A P+ +ER V ++G P+A
Sbjct: 387 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQ 446
Query: 164 RQICAVILE----SPPKGATIPYH---PSLSLGTVLLSANQGFSVQGQYGAVTPAEV 213
+I + E +P + + H PS + G V+ +G + +T AEV
Sbjct: 447 GRIFGKLKEENFFNPKEEVKLEAHIRVPSSTAGRVI---GKGGKTVNELQNLTSAEV 500
Score = 61.2 bits (147), Expect = 2e-09
Identities = 41/125 (32%), Positives = 60/125 (48%), Gaps = 8/125 (6%)
Query: 29 VGSIIGKKGETVKRIREQSSARITISEGSCP---ERITTITGSTAAVFHAVSMIAFKLDE 85
VG+IIGKKG +K++ + A I I+ P ER+ ITG A F A I KL E
Sbjct: 396 VGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQGRIFGKLKE 455
Query: 86 DLCAAPANGGNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPNS 145
+ P + + +P+S G +IGK G + E++ T A+V V D P+
Sbjct: 456 ENFFNPKE-----EVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDE 510
Query: 146 TERAV 150
E +
Sbjct: 511 NEEVI 515
Score = 43.5 bits (101), Expect = 3e-04
Identities = 49/226 (21%), Positives = 84/226 (37%), Gaps = 62/226 (27%)
Query: 90 APANGGNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPNSTERA 149
AP + LR+++P G++IGK G IK I + T ++V + + E+
Sbjct: 182 APGGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKP 241
Query: 150 VTVSGVPDAIILCVRQICAVILESPPKGATIPYHPSLSLGTVLLSANQGFSVQGQYGAVT 209
VT+ P+ + C +ILE K
Sbjct: 242 VTIHATPEG----TSEACRMILEIMQK--------------------------------- 264
Query: 210 PAEVTKLQQLSSHAVPFATPSVVPGLDPGTQTSSQEFLVPNDLIGCVIGRQGSKISEIRQ 269
A+ TKL + +P + L N L+G +IG++G + +I
Sbjct: 265 EADETKLAE----EIPL------------------KILAHNGLVGRLIGKEGRNLKKIEH 302
Query: 270 MSGAHIKIGNQAEGA---GERHVTITGSPVSIALAQYLITACLETA 312
+G I I + + + ER +T+ G+ + A A+ I L A
Sbjct: 303 ETGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREA 348
Score = 30.8 bits (68), Expect = 2.3
Identities = 16/59 (27%), Positives = 29/59 (49%), Gaps = 4/59 (6%)
Query: 6 GGLEEE----PELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSCPE 60
G L+EE P+ + L + + G +IGK G+TV ++ +SA + + P+
Sbjct: 451 GKLKEENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPD 509
>gi|56237027 insulin-like growth factor 2 mRNA binding protein 1
isoform 1 [Homo sapiens]
Length = 577
Score = 71.6 bits (174), Expect = 1e-12
Identities = 73/299 (24%), Positives = 134/299 (44%), Gaps = 37/299 (12%)
Query: 16 ITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITI---SEGSCPERITTITGSTAAV 72
+ + LR+L+ + VG+IIGK+G T++ I +Q+ ++I + E+ ++ +
Sbjct: 194 VDIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKAISVHSTPEGC 253
Query: 73 FHAVSMIAFKLDEDLCAAPANGGNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRETTG 132
A MI + ++ + V L+++ + G LIGK G +K++ + T
Sbjct: 254 SSACKMILEIMHKEA------KDTKTADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTE 307
Query: 133 AQVQVAG--DLLPNSTERAVTVSGVPDAIILCVRQICAVILESPPKGATIPYHPSLSLGT 190
++ ++ DL + ER +TV G + ++I + E+ ++SL +
Sbjct: 308 TKITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVREAYENDVA-----AMSLQS 362
Query: 191 VLLSANQGFSVQGQYGAVTPAEVTKLQQLSSHAVPFATPSVVPGLDPGT---QTSSQEFL 247
L+ + G + A SS AVP PS V G P + Q QE +
Sbjct: 363 HLI-PGLNLAAVGLFPA------------SSSAVP-PPPSSVTGAAPYSSFMQAPEQEMV 408
Query: 248 ---VPNDLIGCVIGRQGSKISEIRQMSGAHIKIG-NQAEGAGERHVTITGSPVSIALAQ 302
+P +G +IG++G I ++ + + A IKI + + R V ITG P + AQ
Sbjct: 409 QVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQ 467
Score = 65.1 bits (157), Expect = 1e-10
Identities = 41/134 (30%), Positives = 68/134 (50%), Gaps = 8/134 (5%)
Query: 20 LRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSCPE---RITTITGSTAAVFHAV 76
+++ + + VG+IIGKKG+ +K++ +SA I I+ P+ R+ ITG A F A
Sbjct: 408 VQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQ 467
Query: 77 SMIAFKLDEDLCAAPANGGNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQ 136
I KL E+ P + + +PAS G +IGK G + E++ T A+V
Sbjct: 468 GRIYGKLKEENFFGPKE-----EVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVV 522
Query: 137 VAGDLLPNSTERAV 150
V D P+ ++ +
Sbjct: 523 VPRDQTPDENDQVI 536
Score = 42.0 bits (97), Expect = 0.001
Identities = 28/89 (31%), Positives = 43/89 (48%), Gaps = 7/89 (7%)
Query: 90 APANGGNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPNSTERA 149
APA V P LRL++P G++IGK G I+ I + T +++ V + E+A
Sbjct: 187 APAKQQQVDIP---LRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKA 243
Query: 150 VTVSGVPDAIILCVRQICAVILESPPKGA 178
++V P+ C +ILE K A
Sbjct: 244 ISVHSTPEG----CSSACKMILEIMHKEA 268
Score = 32.7 bits (73), Expect = 0.60
Identities = 20/86 (23%), Positives = 38/86 (44%), Gaps = 4/86 (4%)
Query: 6 GGLEEE----PELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSCPER 61
G L+EE P+ + L + + G +IGK G+TV ++ ++A + + P+
Sbjct: 472 GKLKEENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPDE 531
Query: 62 ITTITGSTAAVFHAVSMIAFKLDEDL 87
+ F+A M K+ + L
Sbjct: 532 NDQVIVKIIGHFYASQMAQRKIRDIL 557
>gi|238624257 insulin-like growth factor 2 mRNA binding protein 1
isoform 2 [Homo sapiens]
Length = 438
Score = 65.1 bits (157), Expect = 1e-10
Identities = 41/134 (30%), Positives = 68/134 (50%), Gaps = 8/134 (5%)
Query: 20 LRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSCPE---RITTITGSTAAVFHAV 76
+++ + + VG+IIGKKG+ +K++ +SA I I+ P+ R+ ITG A F A
Sbjct: 269 VQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQ 328
Query: 77 SMIAFKLDEDLCAAPANGGNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQ 136
I KL E+ P + + +PAS G +IGK G + E++ T A+V
Sbjct: 329 GRIYGKLKEENFFGPKE-----EVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVV 383
Query: 137 VAGDLLPNSTERAV 150
V D P+ ++ +
Sbjct: 384 VPRDQTPDENDQVI 397
Score = 61.6 bits (148), Expect = 1e-09
Identities = 50/194 (25%), Positives = 83/194 (42%), Gaps = 45/194 (23%)
Query: 10 EEPELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGS-----CPERITT 64
E+ + + L++L H VG +IGK+G +K++ + + +ITIS PER T
Sbjct: 130 EQTRQADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTIT 189
Query: 65 ITGSTAAVFHAVSMIAFKLDE----DLCAA------------------PANGGNVSRPPV 102
+ G+ A I K+ E D+ A PA+ V PP
Sbjct: 190 VKGAIENCCRAEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPPS 249
Query: 103 T------------------LRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPN 144
+ +++ IPA G++IGK G IK++ A +++A P+
Sbjct: 250 SVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPD 309
Query: 145 STERAVTVSGVPDA 158
S R V ++G P+A
Sbjct: 310 SKVRMVIITGPPEA 323
Score = 52.4 bits (124), Expect = 7e-07
Identities = 56/210 (26%), Positives = 95/210 (45%), Gaps = 28/210 (13%)
Query: 102 VTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAG--DLLPNSTERAVTVSGVPDAI 159
V L+++ + G LIGK G +K++ + T ++ ++ DL + ER +TV G +
Sbjct: 138 VPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENC 197
Query: 160 ILCVRQICAVILESPPKGATIPYHPSLSLGTVLLSANQGFSVQGQYGAVTPAEVTKLQQL 219
++I + E+ ++SL + L+ +V + PA
Sbjct: 198 CRAEQEIMKKVREAYENDVA-----AMSLQSHLIPGLNLAAV-----GLFPA-------- 239
Query: 220 SSHAVPFATPSVVPGLDPGT---QTSSQEFL---VPNDLIGCVIGRQGSKISEIRQMSGA 273
SS AVP PS V G P + Q QE + +P +G +IG++G I ++ + + A
Sbjct: 240 SSSAVP-PPPSSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASA 298
Query: 274 HIKIG-NQAEGAGERHVTITGSPVSIALAQ 302
IKI + + R V ITG P + AQ
Sbjct: 299 SIKIAPPETPDSKVRMVIITGPPEAQFKAQ 328
Score = 32.7 bits (73), Expect = 0.60
Identities = 20/86 (23%), Positives = 38/86 (44%), Gaps = 4/86 (4%)
Query: 6 GGLEEE----PELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSCPER 61
G L+EE P+ + L + + G +IGK G+TV ++ ++A + + P+
Sbjct: 333 GKLKEENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPDE 392
Query: 62 ITTITGSTAAVFHAVSMIAFKLDEDL 87
+ F+A M K+ + L
Sbjct: 393 NDQVIVKIIGHFYASQMAQRKIRDIL 418
>gi|122937472 bicaudal C homolog 1 [Homo sapiens]
Length = 974
Score = 52.8 bits (125), Expect = 6e-07
Identities = 55/224 (24%), Positives = 98/224 (43%), Gaps = 20/224 (8%)
Query: 102 VTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPNSTERA--VTVSGVP--- 156
VTL++ + ++ +IGK G IK++ E TG + N E++ V+++G P
Sbjct: 133 VTLKMDVSHTEHSHVIGKGGNNIKKVMEETGCHIHFPDSNRNNQAEKSNQVSIAGQPAGV 192
Query: 157 DAIILCVRQICAVIL--ESPPKGATIPYHPSLSLGTVLLSANQGFSV-----QGQYGAVT 209
++ + +R++ ++L E P G P S +S SV YGA
Sbjct: 193 ESARVRIRELLPLVLMFELPIAGILQPVPDPNSPSIQHISQTYNISVSFKQRSRMYGATV 252
Query: 210 PAEVTKLQQLSSHAVPFATPSVVPGLDPGTQTSSQEFLVPNDLIG----CVIGRQGSKIS 265
+ + Q ++ AV T ++ L G+ S+ D+ ++GR GS I
Sbjct: 253 ---IVRGSQNNTSAVKEGTAMLLEHL-AGSLASAIPVSTQLDIAAQHHLFMMGRNGSNIK 308
Query: 266 EIRQMSGAHIKIGNQAEGAGERHVTITGSPVSIALAQYLITACL 309
I Q +GA I + + + V + G+ S+ LA+ + CL
Sbjct: 309 HIMQRTGAQIHFPDPSNPQKKSTVYLQGTIESVCLARQYLMGCL 352
Score = 30.4 bits (67), Expect = 3.0
Identities = 19/59 (32%), Positives = 31/59 (52%), Gaps = 3/59 (5%)
Query: 94 GGNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPNSTERAVTV 152
G S PV+ +L I A ++G+ G+ IK I + TGAQ+ P++ ++ TV
Sbjct: 277 GSLASAIPVSTQLDIAAQHHLFMMGRNGSNIKHIMQRTGAQIHFPD---PSNPQKKSTV 332
>gi|38683807 ankyrin repeat domain protein 17 isoform a [Homo sapiens]
Length = 2603
Score = 52.4 bits (124), Expect = 7e-07
Identities = 38/117 (32%), Positives = 55/117 (47%), Gaps = 6/117 (5%)
Query: 243 SQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAEGAGERHVTITGSPVSIALAQ 302
S++ VP+ +I VIGR G I+ IR+ +GAHI I Q + G+R +TI G S A
Sbjct: 1727 SKKVSVPSTVISRVIGRGGCNINAIREFTGAHIDIDKQKDKTGDRIITIRGGTESTRQAT 1786
Query: 303 YLITACLETAKS------TSGGTPSSAPADLPAPFSPPLTALPTAPPGLLGTPYAIS 353
LI A ++ SS+ +P TA T+ G+ T A+S
Sbjct: 1787 QLINALIKDPDKEIDELIPKNRLKSSSANSKIGSSAPTTTAANTSLMGIKMTTVALS 1843
Score = 31.2 bits (69), Expect = 1.7
Identities = 19/67 (28%), Positives = 36/67 (53%), Gaps = 3/67 (4%)
Query: 105 RLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPNST-ERAVTVSGVPDAIILCV 163
++ +P++ +IG+ G I IRE TGA + + D + T +R +T+ G ++
Sbjct: 1729 KVSVPSTVISRVIGRGGCNINAIREFTGAHIDI--DKQKDKTGDRIITIRGGTESTRQAT 1786
Query: 164 RQICAVI 170
+ I A+I
Sbjct: 1787 QLINALI 1793
>gi|38683816 ankyrin repeat domain protein 17 isoform b [Homo sapiens]
Length = 2352
Score = 52.4 bits (124), Expect = 7e-07
Identities = 38/117 (32%), Positives = 55/117 (47%), Gaps = 6/117 (5%)
Query: 243 SQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAEGAGERHVTITGSPVSIALAQ 302
S++ VP+ +I VIGR G I+ IR+ +GAHI I Q + G+R +TI G S A
Sbjct: 1476 SKKVSVPSTVISRVIGRGGCNINAIREFTGAHIDIDKQKDKTGDRIITIRGGTESTRQAT 1535
Query: 303 YLITACLETAKS------TSGGTPSSAPADLPAPFSPPLTALPTAPPGLLGTPYAIS 353
LI A ++ SS+ +P TA T+ G+ T A+S
Sbjct: 1536 QLINALIKDPDKEIDELIPKNRLKSSSANSKIGSSAPTTTAANTSLMGIKMTTVALS 1592
Score = 31.2 bits (69), Expect = 1.7
Identities = 19/67 (28%), Positives = 36/67 (53%), Gaps = 3/67 (4%)
Query: 105 RLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPNST-ERAVTVSGVPDAIILCV 163
++ +P++ +IG+ G I IRE TGA + + D + T +R +T+ G ++
Sbjct: 1478 KVSVPSTVISRVIGRGGCNINAIREFTGAHIDI--DKQKDKTGDRIITIRGGTESTRQAT 1535
Query: 164 RQICAVI 170
+ I A+I
Sbjct: 1536 QLINALI 1542
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.131 0.376
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,410,209
Number of Sequences: 37866
Number of extensions: 933930
Number of successful extensions: 6256
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 105
Number of HSP's successfully gapped in prelim test: 272
Number of HSP's that attempted gapping in prelim test: 4783
Number of HSP's gapped (non-prelim): 1549
length of query: 403
length of database: 18,247,518
effective HSP length: 105
effective length of query: 298
effective length of database: 14,271,588
effective search space: 4252933224
effective search space used: 4252933224
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.