Search of human proteins with 146198864

Search of human proteins with 146198864

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|146198864 potassium channel tetramerisation domain
containing 4 [Homo sapiens]
         (259 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|146198864 potassium channel tetramerisation domain containing...   523   e-149
gi|189571693 potassium channel tetramerisation domain containing...    97   1e-20
gi|189571691 potassium channel tetramerisation domain containing...    97   1e-20
gi|71143104 potassium channel tetramerisation domain containing ...    96   2e-20
gi|194018443 potassium channel tetramerisation domain containing...    92   3e-19
gi|194018441 potassium channel tetramerisation domain containing...    92   3e-19
gi|194018439 potassium channel tetramerisation domain containing...    92   3e-19
gi|218505694 potassium channel tetramerisation domain containing...    88   6e-18
gi|209969708 potassium channel tetramerisation domain containing...    88   6e-18
gi|40217617 potassium channel tetramerisation domain containing ...    88   6e-18
gi|38198663 potassium channel tetramerisation domain containing ...    80   2e-15
gi|13994353 potassium channel tetramerisation domain containing ...    76   3e-14
gi|19923973 potassium channel tetramerisation domain containing ...    72   4e-13
gi|51036594 potassium channel tetramerisation domain containing ...    72   5e-13
gi|55926200 potassium channel tetramerisation domain containing ...    71   1e-12
gi|23308551 potassium channel tetramerisation domain containing ...    69   3e-12
gi|169234778 potassium channel tetramerisation domain containing...    69   4e-12
gi|223005950 SH3KBP1 binding protein 1 [Homo sapiens]                  68   7e-12
gi|30578412 potassium channel tetramerisation domain containing ...    67   1e-11
gi|40807368 potassium channel regulator isoform 2 [Homo sapiens]       66   3e-11
gi|27734697 potassium channel regulator isoform 1 [Homo sapiens]       66   3e-11
gi|45387953 potassium channel tetramerization domain containing ...    62   4e-10
gi|155369221 potassium channel tetramerisation domain containing...    62   4e-10
gi|9506651 potassium channel tetramerisation domain containing 5...    62   5e-10
gi|10863937 tumor necrosis factor, alpha-induced protein 1 [Homo...    62   6e-10
gi|46255026 potassium channel tetramerisation domain containing ...    62   6e-10
gi|53829365 potassium channel tetramerisation domain containing ...    61   8e-10
gi|142356950 potassium channel tetramerisation domain containing...    59   3e-09
gi|27436981 potassium voltage-gated channel, Shal-related subfam...    56   3e-08
gi|9789987 potassium voltage-gated channel, Shal-related subfami...    54   2e-07

>gi|146198864 potassium channel tetramerisation domain containing 4
           [Homo sapiens]
          Length = 259

 Score =  523 bits (1347), Expect = e-149
 Identities = 259/259 (100%), Positives = 259/259 (100%)

Query: 1   MERKINRREKEKEYEGKHNSLEDTDQGKNCKSTLMTLNVGGYLYITQKQTLTKYPDTFLE 60
           MERKINRREKEKEYEGKHNSLEDTDQGKNCKSTLMTLNVGGYLYITQKQTLTKYPDTFLE
Sbjct: 1   MERKINRREKEKEYEGKHNSLEDTDQGKNCKSTLMTLNVGGYLYITQKQTLTKYPDTFLE 60

Query: 61  GIVNGKILCPFDADGHYFIDRDGLLFRHVLNFLRNGELLLPEGFRENQLLAQEAEFFQLK 120
           GIVNGKILCPFDADGHYFIDRDGLLFRHVLNFLRNGELLLPEGFRENQLLAQEAEFFQLK
Sbjct: 61  GIVNGKILCPFDADGHYFIDRDGLLFRHVLNFLRNGELLLPEGFRENQLLAQEAEFFQLK 120

Query: 121 GLAEEVKSRWEKEQLTPRETTFLEITDNHDRSQGLRIFCNAPDFISKIKSRIVLVSKSRL 180
           GLAEEVKSRWEKEQLTPRETTFLEITDNHDRSQGLRIFCNAPDFISKIKSRIVLVSKSRL
Sbjct: 121 GLAEEVKSRWEKEQLTPRETTFLEITDNHDRSQGLRIFCNAPDFISKIKSRIVLVSKSRL 180

Query: 181 DGFPEEFSISSNIIQFKYFIKSENGTRLVLKEDNTFVCTLETLKFEAIMMALKCGFRLLT 240
           DGFPEEFSISSNIIQFKYFIKSENGTRLVLKEDNTFVCTLETLKFEAIMMALKCGFRLLT
Sbjct: 181 DGFPEEFSISSNIIQFKYFIKSENGTRLVLKEDNTFVCTLETLKFEAIMMALKCGFRLLT 240

Query: 241 SLDCSKGSIVHSDALHFIK 259
           SLDCSKGSIVHSDALHFIK
Sbjct: 241 SLDCSKGSIVHSDALHFIK 259


>gi|189571693 potassium channel tetramerisation domain containing 6
           [Homo sapiens]
          Length = 237

 Score = 97.4 bits (241), Expect = 1e-20
 Identities = 48/90 (53%), Positives = 62/90 (68%)

Query: 35  MTLNVGGYLYITQKQTLTKYPDTFLEGIVNGKILCPFDADGHYFIDRDGLLFRHVLNFLR 94
           +TLNVGG+LY T   TLT+YPD+ L  +  G      D  G+YFIDRDG LFR+VLNFLR
Sbjct: 14  VTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDPQGNYFIDRDGPLFRYVLNFLR 73

Query: 95  NGELLLPEGFRENQLLAQEAEFFQLKGLAE 124
             EL LP  F+E  LL +EA+F+Q++ L +
Sbjct: 74  TSELTLPLDFKEFDLLRKEADFYQIEPLIQ 103


>gi|189571691 potassium channel tetramerisation domain containing 6
           [Homo sapiens]
          Length = 237

 Score = 97.4 bits (241), Expect = 1e-20
 Identities = 48/90 (53%), Positives = 62/90 (68%)

Query: 35  MTLNVGGYLYITQKQTLTKYPDTFLEGIVNGKILCPFDADGHYFIDRDGLLFRHVLNFLR 94
           +TLNVGG+LY T   TLT+YPD+ L  +  G      D  G+YFIDRDG LFR+VLNFLR
Sbjct: 14  VTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDPQGNYFIDRDGPLFRYVLNFLR 73

Query: 95  NGELLLPEGFRENQLLAQEAEFFQLKGLAE 124
             EL LP  F+E  LL +EA+F+Q++ L +
Sbjct: 74  TSELTLPLDFKEFDLLRKEADFYQIEPLIQ 103


>gi|71143104 potassium channel tetramerisation domain containing 21
           [Homo sapiens]
          Length = 260

 Score = 96.3 bits (238), Expect = 2e-20
 Identities = 52/114 (45%), Positives = 73/114 (64%), Gaps = 1/114 (0%)

Query: 35  MTLNVGGYLYITQKQTLTKYPDTFLEGIVNGKILCPFDADGHYFIDRDGLLFRHVLNFLR 94
           +TLNVGG LY T   TLT +PD+ L  + +GK+    D+ G+ FIDRDG +FR++LNFLR
Sbjct: 5   ITLNVGGKLYTTSLATLTSFPDSMLGAMFSGKMPTKRDSQGNCFIDRDGKVFRYILNFLR 64

Query: 95  NGELLLPEGFRENQLLAQEAEFFQLKGLAEEVKSRWEKEQLTPRETTFLEITDN 148
              L LPE F+E  LL +EA+F+Q++ L E ++ + E E     +   L IT N
Sbjct: 65  TSHLDLPEDFQEMGLLRREADFYQVQPLIEALQEK-EVELSKAEKNAMLNITLN 117


>gi|194018443 potassium channel tetramerisation domain containing 15
           isoform 2 [Homo sapiens]
          Length = 283

 Score = 92.4 bits (228), Expect = 3e-19
 Identities = 45/99 (45%), Positives = 70/99 (70%), Gaps = 2/99 (2%)

Query: 37  LNVGGYLYITQKQTLTKYPDTFLEGIVNGKILCPFDA-DGHYFIDRDGLLFRHVLNFLRN 95
           ++VGG++Y +   TLTKYPD+ +  + NG      D+   HYFIDRDG +FR+VL+FLR 
Sbjct: 60  IDVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDSLKQHYFIDRDGEIFRYVLSFLRT 119

Query: 96  GELLLPEGFRENQLLAQEAEFFQLKGLAEEVKSRWEKEQ 134
            +LLLP+ F++  LL +EA ++QL+ +  E++ RW++EQ
Sbjct: 120 SKLLLPDDFKDFSLLYEEARYYQLQPMVRELE-RWQQEQ 157


>gi|194018441 potassium channel tetramerisation domain containing 15
           isoform 2 [Homo sapiens]
          Length = 283

 Score = 92.4 bits (228), Expect = 3e-19
 Identities = 45/99 (45%), Positives = 70/99 (70%), Gaps = 2/99 (2%)

Query: 37  LNVGGYLYITQKQTLTKYPDTFLEGIVNGKILCPFDA-DGHYFIDRDGLLFRHVLNFLRN 95
           ++VGG++Y +   TLTKYPD+ +  + NG      D+   HYFIDRDG +FR+VL+FLR 
Sbjct: 60  IDVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDSLKQHYFIDRDGEIFRYVLSFLRT 119

Query: 96  GELLLPEGFRENQLLAQEAEFFQLKGLAEEVKSRWEKEQ 134
            +LLLP+ F++  LL +EA ++QL+ +  E++ RW++EQ
Sbjct: 120 SKLLLPDDFKDFSLLYEEARYYQLQPMVRELE-RWQQEQ 157


>gi|194018439 potassium channel tetramerisation domain containing 15
           isoform 1 [Homo sapiens]
          Length = 234

 Score = 92.4 bits (228), Expect = 3e-19
 Identities = 45/99 (45%), Positives = 70/99 (70%), Gaps = 2/99 (2%)

Query: 37  LNVGGYLYITQKQTLTKYPDTFLEGIVNGKILCPFDA-DGHYFIDRDGLLFRHVLNFLRN 95
           ++VGG++Y +   TLTKYPD+ +  + NG      D+   HYFIDRDG +FR+VL+FLR 
Sbjct: 60  IDVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDSLKQHYFIDRDGEIFRYVLSFLRT 119

Query: 96  GELLLPEGFRENQLLAQEAEFFQLKGLAEEVKSRWEKEQ 134
            +LLLP+ F++  LL +EA ++QL+ +  E++ RW++EQ
Sbjct: 120 SKLLLPDDFKDFSLLYEEARYYQLQPMVRELE-RWQQEQ 157


>gi|218505694 potassium channel tetramerisation domain containing 1
           isoform b [Homo sapiens]
          Length = 865

 Score = 88.2 bits (217), Expect = 6e-18
 Identities = 43/103 (41%), Positives = 73/103 (70%), Gaps = 2/103 (1%)

Query: 37  LNVGGYLYITQKQTLTKYPDTFLEGIVNGKILCPFDA-DGHYFIDRDGLLFRHVLNFLRN 95
           ++VGG++Y +   TLTKYP++ +  + +G      D+   HYFIDRDG +FR++LNFLR 
Sbjct: 642 IDVGGHMYTSSLATLTKYPESRIGRLFDGTEPIVLDSLKQHYFIDRDGQMFRYILNFLRT 701

Query: 96  GELLLPEGFRENQLLAQEAEFFQLKGLAEEVKSRWEKEQLTPR 138
            +LL+P+ F++  LL +EA++FQL+ +  E++ RW++++ T R
Sbjct: 702 SKLLIPDDFKDYTLLYEEAKYFQLQPMLLEME-RWKQDRETGR 743


>gi|209969708 potassium channel tetramerisation domain containing 1
           isoform a [Homo sapiens]
          Length = 257

 Score = 88.2 bits (217), Expect = 6e-18
 Identities = 43/103 (41%), Positives = 73/103 (70%), Gaps = 2/103 (1%)

Query: 37  LNVGGYLYITQKQTLTKYPDTFLEGIVNGKILCPFDA-DGHYFIDRDGLLFRHVLNFLRN 95
           ++VGG++Y +   TLTKYP++ +  + +G      D+   HYFIDRDG +FR++LNFLR 
Sbjct: 34  IDVGGHMYTSSLATLTKYPESRIGRLFDGTEPIVLDSLKQHYFIDRDGQMFRYILNFLRT 93

Query: 96  GELLLPEGFRENQLLAQEAEFFQLKGLAEEVKSRWEKEQLTPR 138
            +LL+P+ F++  LL +EA++FQL+ +  E++ RW++++ T R
Sbjct: 94  SKLLIPDDFKDYTLLYEEAKYFQLQPMLLEME-RWKQDRETGR 135


>gi|40217617 potassium channel tetramerisation domain containing 1
           isoform a [Homo sapiens]
          Length = 257

 Score = 88.2 bits (217), Expect = 6e-18
 Identities = 43/103 (41%), Positives = 73/103 (70%), Gaps = 2/103 (1%)

Query: 37  LNVGGYLYITQKQTLTKYPDTFLEGIVNGKILCPFDA-DGHYFIDRDGLLFRHVLNFLRN 95
           ++VGG++Y +   TLTKYP++ +  + +G      D+   HYFIDRDG +FR++LNFLR 
Sbjct: 34  IDVGGHMYTSSLATLTKYPESRIGRLFDGTEPIVLDSLKQHYFIDRDGQMFRYILNFLRT 93

Query: 96  GELLLPEGFRENQLLAQEAEFFQLKGLAEEVKSRWEKEQLTPR 138
            +LL+P+ F++  LL +EA++FQL+ +  E++ RW++++ T R
Sbjct: 94  SKLLIPDDFKDYTLLYEEAKYFQLQPMLLEME-RWKQDRETGR 135


>gi|38198663 potassium channel tetramerisation domain containing 8
           [Homo sapiens]
          Length = 473

 Score = 79.7 bits (195), Expect = 2e-15
 Identities = 46/126 (36%), Positives = 72/126 (57%), Gaps = 13/126 (10%)

Query: 34  LMTLNVGGYLYITQKQTLTKYPDTFLEGIVN-----------GKILCPFDADGHYFIDRD 82
           ++ LNVGG +Y+T+  TL   PD+ L  + +           G++  P D+   +FIDRD
Sbjct: 45  VVELNVGGQVYVTKHSTLLSVPDSTLASMFSPSSPRGGARRRGEL--PRDSRARFFIDRD 102

Query: 83  GLLFRHVLNFLRNGELLLPEGFRENQLLAQEAEFFQLKGLAEEVKSRWEKEQLTPRETTF 142
           G LFR+VL++LR+ +L LPE F E + L +EAE+FQL  L + +  +  K+     E   
Sbjct: 103 GFLFRYVLDYLRDKQLALPEHFPEKERLLREAEYFQLTDLVKLLSPKVTKQNSLNDEGCQ 162

Query: 143 LEITDN 148
            ++ DN
Sbjct: 163 SDLEDN 168


>gi|13994353 potassium channel tetramerisation domain containing 10
           [Homo sapiens]
          Length = 313

 Score = 75.9 bits (185), Expect = 3e-14
 Identities = 43/103 (41%), Positives = 65/103 (63%), Gaps = 1/103 (0%)

Query: 26  QGKNCKSTLMTLNVGGYLYITQKQTLTKYPDTFLEGIVNGKILCPFDADGHYFIDRDGLL 85
           +G +  S  + LNVGG LY T  QTLTK  DT L+ + +G++    D++G   IDR G  
Sbjct: 25  KGTSPSSKYVKLNVGGALYYTTMQTLTKQ-DTMLKAMFSGRMEVLTDSEGWILIDRCGKH 83

Query: 86  FRHVLNFLRNGELLLPEGFRENQLLAQEAEFFQLKGLAEEVKS 128
           F  +LN+LR+G + LPE  RE + L  EA+++ ++GL EE ++
Sbjct: 84  FGTILNYLRDGAVPLPESRREIEELLAEAKYYLVQGLVEECQA 126


>gi|19923973 potassium channel tetramerisation domain containing 12
           [Homo sapiens]
          Length = 325

 Score = 72.4 bits (176), Expect = 4e-13
 Identities = 36/95 (37%), Positives = 61/95 (64%), Gaps = 2/95 (2%)

Query: 34  LMTLNVGGYLYITQKQTLTKYPDTFLEGIVNGKILCPF--DADGHYFIDRDGLLFRHVLN 91
           ++ LNVGG +Y+T++ T+   PD+ L  +   +       D+ G +F+DRDG LFR++L+
Sbjct: 35  IVELNVGGQVYVTRRCTVVSVPDSLLWRMFTQQQPQELARDSKGRFFLDRDGFLFRYILD 94

Query: 92  FLRNGELLLPEGFRENQLLAQEAEFFQLKGLAEEV 126
           +LR+ +L+LP+ F E   L +EAE+F+L  L   +
Sbjct: 95  YLRDLQLVLPDYFPERSRLQREAEYFELPELVRRL 129


>gi|51036594 potassium channel tetramerisation domain containing 11
           [Homo sapiens]
          Length = 232

 Score = 72.0 bits (175), Expect = 5e-13
 Identities = 45/133 (33%), Positives = 65/133 (48%), Gaps = 24/133 (18%)

Query: 75  GHYFIDRDGLLFRHVLNFLRNGELLLPEGFRENQLLAQEAEFFQLKGLAEEVKSRWEKEQ 134
           GHYFIDRDG  FRH+LNFLR G L LP G+ E  LL  EA+F+Q++ L + ++   E  Q
Sbjct: 22  GHYFIDRDGKAFRHILNFLRLGRLDLPRGYGETALLRAEADFYQIRPLLDALR-ELEASQ 80

Query: 135 LTPRETTFLEITD----------------NHDRSQGLRI-------FCNAPDFISKIKSR 171
            TP  T  L   D                +H     +++       FC   + +  +++R
Sbjct: 81  GTPAPTAALLHADVDVSPRLVHFSARRGPHHYELSSVQVDTFRANLFCTDSECLGALRAR 140

Query: 172 IVLVSKSRLDGFP 184
             + S  R +G P
Sbjct: 141 FGVASGDRAEGSP 153


>gi|55926200 potassium channel tetramerisation domain containing 16
           [Homo sapiens]
          Length = 428

 Score = 70.9 bits (172), Expect = 1e-12
 Identities = 38/95 (40%), Positives = 59/95 (62%), Gaps = 4/95 (4%)

Query: 34  LMTLNVGGYLYITQKQTLTKYPDTFLEGIVNGKILCPFD----ADGHYFIDRDGLLFRHV 89
           ++ LNVGG +Y T+  TL   P + L  + + K     D    + G +FIDRDG LFR++
Sbjct: 26  VVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRDTANDLAKDSKGRFFIDRDGFLFRYI 85

Query: 90  LNFLRNGELLLPEGFRENQLLAQEAEFFQLKGLAE 124
           L++LR+ +++LP+ F E   L +EAE+FQL  L +
Sbjct: 86  LDYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVK 120


>gi|23308551 potassium channel tetramerisation domain containing 7
           [Homo sapiens]
          Length = 289

 Score = 69.3 bits (168), Expect = 3e-12
 Identities = 37/95 (38%), Positives = 59/95 (62%), Gaps = 3/95 (3%)

Query: 34  LMTLNVGGYLYITQKQTLTKYPDTFLEGIVNGKILCPFDADGHYFIDRDGLLFRHVLNFL 93
           ++ LN+GG  + T+  TL  Y DT L  + +G+   P D++G YFIDRDG  F  VLNFL
Sbjct: 52  VVPLNIGGAHFTTRLSTLRCYEDTMLAAMFSGRHYIPTDSEGRYFIDRDGTHFGDVLNFL 111

Query: 94  RNGELLLPEGFRENQLLAQEAEFFQLKGLAEEVKS 128
           R+G+L   E  R    + +EA+++ +  L E++++
Sbjct: 112 RSGDLPPRERVR---AVYKEAQYYAIGPLLEQLEN 143


>gi|169234778 potassium channel tetramerisation domain containing 17
           [Homo sapiens]
          Length = 297

 Score = 68.9 bits (167), Expect = 4e-12
 Identities = 40/101 (39%), Positives = 60/101 (59%), Gaps = 2/101 (1%)

Query: 37  LNVGGYLYITQKQTLTKYPDTFLEGIVNGKIL-CPFDADGHYFIDRDGLLFRHVLNFLRN 95
           LNVGG +++T +QTL +   +FL  +  G+ L    D  G Y IDRD   F  +LNFLR+
Sbjct: 35  LNVGGTVFLTTRQTLCREQKSFLSRLCQGEELQSDRDETGAYLIDRDPTYFGPILNFLRH 94

Query: 96  GELLLPEGFRENQLLAQEAEFFQLKGLAEEVKSRWEKEQLT 136
           G+L+L +   E  +L +EAEF+ +  L   +K R E++  T
Sbjct: 95  GKLVLDKDMAEEGVL-EEAEFYNIGPLIRIIKDRMEEKDYT 134


>gi|223005950 SH3KBP1 binding protein 1 [Homo sapiens]
          Length = 707

 Score = 68.2 bits (165), Expect = 7e-12
 Identities = 51/148 (34%), Positives = 72/148 (48%), Gaps = 15/148 (10%)

Query: 37  LNVGGYLYITQKQTLTKYPDTFLEGIVNGKILCPFDADGHYFIDRDGLLFRHVLNFLRNG 96
           LNVGG  + T +QTLT  PD+F   +++G+I    D  G  FIDRD  +F  +LNFLR  
Sbjct: 23  LNVGGKRFSTSRQTLTWIPDSFFSSLLSGRISTLKDETGAIFIDRDPTVFAPILNFLRTK 82

Query: 97  ELLLPEGFRENQLLAQEAEFFQLKGLAEEVKSRWEKEQLTPRETTFLEITDNHDRSQGLR 156
           E L P G   + LL  EA+F+ L  L   ++ R E ++ +     F              
Sbjct: 83  E-LDPRGVHGSSLL-HEAQFYGLTPLVRRLQLREELDRSSCGNVLF-------------N 127

Query: 157 IFCNAPDFISKIKSRIVLVSKSRLDGFP 184
            +   P F  K ++R  LV   +L G P
Sbjct: 128 GYLPPPVFPVKRRNRHSLVGPQQLGGRP 155


>gi|30578412 potassium channel tetramerisation domain containing 13
           [Homo sapiens]
          Length = 329

 Score = 67.4 bits (163), Expect = 1e-11
 Identities = 42/108 (38%), Positives = 64/108 (59%), Gaps = 3/108 (2%)

Query: 32  STLMTLNVGGYLYITQKQTLTKYPDTFLEGIVNGKILCPFDADGHYFIDRDGLLFRHVLN 91
           S  + LNVGG L+ T  +TLT   DT L+ + +G++    DA G   IDR G  F  +LN
Sbjct: 40  SKYVKLNVGGSLHYTTLRTLTGQ-DTMLKAMFSGRVEVLTDAGGWVLIDRSGRHFGTILN 98

Query: 92  FLRNGELLLPEGFRENQLLAQEAEFFQLKGLAE--EVKSRWEKEQLTP 137
           +LR+G + LPE  RE   L  EA ++ ++GL E  ++  + ++E L+P
Sbjct: 99  YLRDGSVPLPESTRELGELLGEARYYLVQGLIEDCQLALQQKRETLSP 146


>gi|40807368 potassium channel regulator isoform 2 [Homo sapiens]
          Length = 229

 Score = 66.2 bits (160), Expect = 3e-11
 Identities = 35/91 (38%), Positives = 57/91 (62%)

Query: 34  LMTLNVGGYLYITQKQTLTKYPDTFLEGIVNGKILCPFDADGHYFIDRDGLLFRHVLNFL 93
           L+TLNVGG ++ T+  T+ ++P + L  +++G+        G  F+DRDG LF  +L+FL
Sbjct: 6   LVTLNVGGKIFTTRFSTIKQFPASRLARMLDGRDQEFKMVGGQIFVDRDGDLFSFILDFL 65

Query: 94  RNGELLLPEGFRENQLLAQEAEFFQLKGLAE 124
           R  +LLLP  F +   L +EA F++L+ L +
Sbjct: 66  RTHQLLLPTEFSDYLRLQREALFYELRSLVD 96


>gi|27734697 potassium channel regulator isoform 1 [Homo sapiens]
          Length = 272

 Score = 66.2 bits (160), Expect = 3e-11
 Identities = 35/91 (38%), Positives = 57/91 (62%)

Query: 34  LMTLNVGGYLYITQKQTLTKYPDTFLEGIVNGKILCPFDADGHYFIDRDGLLFRHVLNFL 93
           L+TLNVGG ++ T+  T+ ++P + L  +++G+        G  F+DRDG LF  +L+FL
Sbjct: 6   LVTLNVGGKIFTTRFSTIKQFPASRLARMLDGRDQEFKMVGGQIFVDRDGDLFSFILDFL 65

Query: 94  RNGELLLPEGFRENQLLAQEAEFFQLKGLAE 124
           R  +LLLP  F +   L +EA F++L+ L +
Sbjct: 66  RTHQLLLPTEFSDYLRLQREALFYELRSLVD 96


>gi|45387953 potassium channel tetramerization domain containing 18
           [Homo sapiens]
          Length = 426

 Score = 62.4 bits (150), Expect = 4e-10
 Identities = 46/161 (28%), Positives = 82/161 (50%), Gaps = 16/161 (9%)

Query: 34  LMTLNVGGYLYITQKQTLTKYPDTFLEGIVNGKILCPFDADGHYFIDRDGLLFRHVLNFL 93
           ++ LNVGG +Y  ++++L ++ D+ L  + +G+     D  G   IDRDG LF+++L++L
Sbjct: 13  VLRLNVGGCIYTARRESLCRFKDSMLASMFSGRFPLKTDESGACVIDRDGRLFKYLLDYL 72

Query: 94  RNGELLLPEGFRENQLLAQEAEFFQLK---GLAEEVKSRWEKEQLTPRETTFLEITDNHD 150
            +GE+ +P   +    L +EA++F +     L++ + +  E   L         +TD  D
Sbjct: 73  -HGEVQIPTDEQTRIALQEEADYFGIPYPYSLSDHLANEMETYSLRSNIELKKALTDFCD 131

Query: 151 RSQGLRIFCNAPDFI---------SKIKSRIVLVSKSRLDG 182
            S GL   CN P            +  +SRI+ V  ++ DG
Sbjct: 132 -SYGL--VCNKPTVWVLHYLNTSGASCESRIIGVYATKTDG 169


>gi|155369221 potassium channel tetramerisation domain containing 19
           [Homo sapiens]
          Length = 926

 Score = 62.4 bits (150), Expect = 4e-10
 Identities = 41/119 (34%), Positives = 58/119 (48%), Gaps = 19/119 (15%)

Query: 34  LMTLNVGGYLYITQKQTLTKYPDTF-----LEGIVNGKILCPFDADGHYFIDRDGLLFRH 88
           ++ + VG + Y T  QTL KYP+       +  I  G+ L          I  DG +FRH
Sbjct: 397 IIKVYVGSHWYATTLQTLLKYPELLSNPQRVYWITYGQTL---------LIHGDGQMFRH 447

Query: 89  VLNFLRNGELLLPEGFRENQLLAQEAEFFQLKGLAE-----EVKSRWEKEQLTPRETTF 142
           +LNFLR G+L LP  F+E  L  QE E + +  L+E     E    W +E+ +  E  F
Sbjct: 448 ILNFLRLGKLFLPSEFKEWPLFCQEVEEYHIPSLSEALAQCEAYKSWTQEKESENEEAF 506



 Score = 38.9 bits (89), Expect = 0.005
 Identities = 29/104 (27%), Positives = 45/104 (43%), Gaps = 4/104 (3%)

Query: 21  LEDTDQGKNCKSTLMTLNVGGYLYITQKQTLTKYPDTFLEGIVNGKILCPFDADGHYFID 80
           +E++         L   NVGG+ +   +  L+++PD+ L    +             FID
Sbjct: 1   MEESGMAHESAEDLFHFNVGGWHFSVPRSKLSQFPDSLLWKEASA---LTSSESQRLFID 57

Query: 81  RDGLLFRHVLNFLRNGELLLPEGFRENQLLAQEAEFFQLKGLAE 124
           RDG  FRHV  +L   +L       E  LL ++A   QL  L +
Sbjct: 58  RDGSTFRHVHYYLYTSKLSF-SSCAELNLLYEQALGLQLMPLLQ 100



 Score = 38.1 bits (87), Expect = 0.008
 Identities = 18/45 (40%), Positives = 27/45 (60%), Gaps = 2/45 (4%)

Query: 86  FRHVLNFLRNGELLLPEGFRENQLLAQEAEFFQLKGLAEEVKSRW 130
           FR ++NFLR+ ++LLP+ F    +L  E E  ++  L E V  RW
Sbjct: 211 FRFIVNFLRSQKILLPDNFSNIDVLEAEVEILEIPALTEAV--RW 253



 Score = 31.2 bits (69), Expect = 0.94
 Identities = 23/65 (35%), Positives = 31/65 (47%), Gaps = 6/65 (9%)

Query: 43  LYITQKQTLTKYPDTFLEGIVNGKILCPFDADG-HYFIDRDGLLFRHVLNFLRNGELLLP 101
           LY      L KYPD+ L     G++      DG   +I  +G+LF+HV N+L    L L 
Sbjct: 286 LYTMALGLLVKYPDSAL-----GQLRIESTLDGSRLYITGNGVLFQHVKNWLGTCRLPLT 340

Query: 102 EGFRE 106
           E   E
Sbjct: 341 ETISE 345


>gi|9506651 potassium channel tetramerisation domain containing 5
           [Homo sapiens]
          Length = 234

 Score = 62.0 bits (149), Expect = 5e-10
 Identities = 38/100 (38%), Positives = 57/100 (57%), Gaps = 3/100 (3%)

Query: 32  STLMTLNVGGYLYITQKQTLTKYPDTFLEGIVNGKILCPFDAD--GHYFIDRDGLLFRHV 89
           S  + LNVGG  ++T +QTL + P +FL  +         D D  G Y IDRD   F  V
Sbjct: 43  SKWVRLNVGGTYFLTTRQTLCRDPKSFLYRLCQADPDLDSDKDETGAYLIDRDPTYFGPV 102

Query: 90  LNFLRNGELLLPEGFRENQLLAQEAEFFQLKGLAEEVKSR 129
           LN+LR+G+L++ +   E  +L +EAEF+ +  L + VK +
Sbjct: 103 LNYLRHGKLVINKDLAEEGVL-EEAEFYNITSLIKLVKDK 141


>gi|10863937 tumor necrosis factor, alpha-induced protein 1 [Homo
           sapiens]
          Length = 316

 Score = 61.6 bits (148), Expect = 6e-10
 Identities = 35/103 (33%), Positives = 60/103 (58%), Gaps = 1/103 (0%)

Query: 26  QGKNCKSTLMTLNVGGYLYITQKQTLTKYPDTFLEGIVNGKILCPFDADGHYFIDRDGLL 85
           +G    +  + LNVGG LY T  + LT++ DT L+ + +G++    D +G   IDR G  
Sbjct: 21  KGGGLGNKYVQLNVGGSLYYTTVRALTRH-DTMLKAMFSGRMEVLTDKEGWILIDRCGKH 79

Query: 86  FRHVLNFLRNGELLLPEGFRENQLLAQEAEFFQLKGLAEEVKS 128
           F  +LN+LR+  + LP+  +E + L  EA+++ ++GL    +S
Sbjct: 80  FGTILNYLRDDTITLPQNRQEIKELMAEAKYYLIQGLVNMCQS 122


>gi|46255026 potassium channel tetramerisation domain containing 3
           [Homo sapiens]
          Length = 815

 Score = 61.6 bits (148), Expect = 6e-10
 Identities = 38/93 (40%), Positives = 52/93 (55%), Gaps = 2/93 (2%)

Query: 34  LMTLNVGGYLYITQKQTLTKYPDTFLEGIVNGKILCPFDADGHYFIDRDGLLFRHVLNFL 93
           ++ LNVGG  + T +QTL   PD+F   +++G+I    D  G  FIDRD   F  +LNFL
Sbjct: 19  IVQLNVGGTRFSTSRQTLMWIPDSFFSSLLSGRISTLRDETGAIFIDRDPAAFAPILNFL 78

Query: 94  RNGELLLPEGFRENQLLAQEAEFFQLKGLAEEV 126
           R  EL L  G   N +L  EAEF+ +  L   +
Sbjct: 79  RTKELDL-RGVSIN-VLRHEAEFYGITPLVRRL 109


>gi|53829365 potassium channel tetramerisation domain containing 2
           [Homo sapiens]
          Length = 263

 Score = 61.2 bits (147), Expect = 8e-10
 Identities = 36/96 (37%), Positives = 56/96 (58%), Gaps = 4/96 (4%)

Query: 37  LNVGGYLYITQKQTLTKYPDTFLEGIV---NGKILCPFDADGHYFIDRDGLLFRHVLNFL 93
           LNVGG  ++T +QTL + P +FL  +    + ++    D  G Y IDRD   F  +LN+L
Sbjct: 76  LNVGGTYFVTTRQTLGREPKSFLCRLCCQEDPELDSDKDETGAYLIDRDPTYFGPILNYL 135

Query: 94  RNGELLLPEGFRENQLLAQEAEFFQLKGLAEEVKSR 129
           R+G+L++ +   E  +L +EAEF+ +  L   VK R
Sbjct: 136 RHGKLIITKELAEEGVL-EEAEFYNIASLVRLVKER 170


>gi|142356950 potassium channel tetramerisation domain containing 14
           [Homo sapiens]
          Length = 255

 Score = 59.3 bits (142), Expect = 3e-09
 Identities = 34/96 (35%), Positives = 55/96 (57%), Gaps = 10/96 (10%)

Query: 32  STLMTLNVGGYLYITQKQTLTKYPDTFLEGIVNGKILCPFDADGHYFIDRDGLLFRHVLN 91
           ST++ LNVGG  + T   TL K+P + L  + +       DA+G +FIDR    FR +L+
Sbjct: 32  STVVELNVGGEFHTTTLGTLRKFPGSKLAEMFSSLAKASTDAEGRFFIDRPSTYFRPILD 91

Query: 92  FLRNGEL---LLPEGFRENQLLAQEAEFFQLKGLAE 124
           +LR G++    +PE +R       EA+F+++K L +
Sbjct: 92  YLRTGQVPTQHIPEVYR-------EAQFYEIKPLVK 120


>gi|27436981 potassium voltage-gated channel, Shal-related
           subfamily, member 1 [Homo sapiens]
          Length = 647

 Score = 56.2 bits (134), Expect = 3e-08
 Identities = 33/69 (47%), Positives = 41/69 (59%), Gaps = 4/69 (5%)

Query: 34  LMTLNVGGYLYITQKQTLTKYPDTFLEGIVNGKILCPFDAD-GHYFIDRDGLLFRHVLNF 92
           ++ +NV G  + T K TL +YPDT L G    +    +DAD G YF DRD  +FRHVLNF
Sbjct: 41  VLVVNVSGRRFETWKNTLDRYPDTLL-GSSEKEFF--YDADSGEYFFDRDPDMFRHVLNF 97

Query: 93  LRNGELLLP 101
            R G L  P
Sbjct: 98  YRTGRLHCP 106


>gi|9789987 potassium voltage-gated channel, Shal-related subfamily,
           member 2 [Homo sapiens]
          Length = 630

 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 30/74 (40%), Positives = 38/74 (51%), Gaps = 2/74 (2%)

Query: 28  KNCKSTLMTLNVGGYLYITQKQTLTKYPDTFLEGIVNGKILCPFDADGHYFIDRDGLLFR 87
           K  +  L+ LNV G  + T + TL +YPDT L          P      YF DRD  +FR
Sbjct: 36  KRTQDALIVLNVSGTRFQTWQDTLERYPDTLLGSSERDFFYHP--ETQQYFFDRDPDIFR 93

Query: 88  HVLNFLRNGELLLP 101
           H+LNF R G+L  P
Sbjct: 94  HILNFYRTGKLHYP 107


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.139    0.403 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,343,495
Number of Sequences: 37866
Number of extensions: 392562
Number of successful extensions: 1147
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 46
Number of HSP's successfully gapped in prelim test: 20
Number of HSP's that attempted gapping in prelim test: 1051
Number of HSP's gapped (non-prelim): 77
length of query: 259
length of database: 18,247,518
effective HSP length: 100
effective length of query: 159
effective length of database: 14,460,918
effective search space: 2299285962
effective search space used: 2299285962
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.