Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 14602435
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|14602435 Williams Beuren syndrome chromosome region 14
isoform beta [Homo sapiens]
(833 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|14602435 Williams Beuren syndrome chromosome region 14 isofor... 1719 0.0
gi|14602439 Williams Beuren syndrome chromosome region 14 isofor... 1710 0.0
gi|14602433 Williams Beuren syndrome chromosome region 14 isofor... 1707 0.0
gi|14602437 Williams Beuren syndrome chromosome region 14 isofor... 1698 0.0
gi|111955326 MLX interacting protein [Homo sapiens] 523 e-148
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 105 2e-22
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 102 2e-21
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 101 2e-21
gi|160707881 formin 2 [Homo sapiens] 96 2e-19
gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 96 2e-19
gi|47132519 Ras association and pleckstrin homology domains 1 is... 95 3e-19
gi|163965366 nascent polypeptide-associated complex alpha subuni... 92 2e-18
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 91 3e-18
gi|116284392 mucin 2 precursor [Homo sapiens] 89 1e-17
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] 85 3e-16
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 84 5e-16
gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [... 83 9e-16
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 82 3e-15
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 82 3e-15
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 82 3e-15
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 82 3e-15
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 81 3e-15
gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens] 80 6e-15
gi|62000702 diacylglycerol kinase kappa [Homo sapiens] 80 8e-15
gi|11386183 WAS protein family, member 2 [Homo sapiens] 80 1e-14
gi|7706501 WW domain binding protein 11 [Homo sapiens] 79 1e-14
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 79 2e-14
gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens] 78 4e-14
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 78 4e-14
gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens] 77 5e-14
>gi|14602435 Williams Beuren syndrome chromosome region 14 isoform
beta [Homo sapiens]
Length = 833
Score = 1719 bits (4451), Expect = 0.0
Identities = 833/833 (100%), Positives = 833/833 (100%)
Query: 1 MAGALAGLAAGLQVPRVAPSPDSDSDTDSEDPSLRRSAGGLLRSQVIHSGHFMVSSPHSD 60
MAGALAGLAAGLQVPRVAPSPDSDSDTDSEDPSLRRSAGGLLRSQVIHSGHFMVSSPHSD
Sbjct: 1 MAGALAGLAAGLQVPRVAPSPDSDSDTDSEDPSLRRSAGGLLRSQVIHSGHFMVSSPHSD 60
Query: 61 SLPRRRDQEGSVGPSDFGPRSIDPTLTRLFECLSLAYSGKLVSPKWKNFKGLKLLCRDKI 120
SLPRRRDQEGSVGPSDFGPRSIDPTLTRLFECLSLAYSGKLVSPKWKNFKGLKLLCRDKI
Sbjct: 61 SLPRRRDQEGSVGPSDFGPRSIDPTLTRLFECLSLAYSGKLVSPKWKNFKGLKLLCRDKI 120
Query: 121 RLNNAIWRAWYIQYVKRRKSPVCGFVTPLQGPEADAHRKPEAVVLEGNYWKRRIEVVMRE 180
RLNNAIWRAWYIQYVKRRKSPVCGFVTPLQGPEADAHRKPEAVVLEGNYWKRRIEVVMRE
Sbjct: 121 RLNNAIWRAWYIQYVKRRKSPVCGFVTPLQGPEADAHRKPEAVVLEGNYWKRRIEVVMRE 180
Query: 181 YHKWRIYYKKRLRKPSREDDLLAPKQAEGRWPPPEQWCKQLFSSVVPVLLGDPEEEPGGR 240
YHKWRIYYKKRLRKPSREDDLLAPKQAEGRWPPPEQWCKQLFSSVVPVLLGDPEEEPGGR
Sbjct: 181 YHKWRIYYKKRLRKPSREDDLLAPKQAEGRWPPPEQWCKQLFSSVVPVLLGDPEEEPGGR 240
Query: 241 QLLDLNCFLSDISDTLFTMTQSGPSPLQLPPEDAYVGNADMIQPDLTPLQPSLDDFMDIS 300
QLLDLNCFLSDISDTLFTMTQSGPSPLQLPPEDAYVGNADMIQPDLTPLQPSLDDFMDIS
Sbjct: 241 QLLDLNCFLSDISDTLFTMTQSGPSPLQLPPEDAYVGNADMIQPDLTPLQPSLDDFMDIS 300
Query: 301 DFFTNSRLPQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARN 360
DFFTNSRLPQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARN
Sbjct: 301 DFFTNSRLPQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARN 360
Query: 361 SCPGPLDSSAFLSSDFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAP 420
SCPGPLDSSAFLSSDFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAP
Sbjct: 361 SCPGPLDSSAFLSSDFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAP 420
Query: 421 PTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYS 480
PTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYS
Sbjct: 421 PTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYS 480
Query: 481 EPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQA 540
EPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQA
Sbjct: 481 EPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQA 540
Query: 541 LEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAER 600
LEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAER
Sbjct: 541 LEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAER 600
Query: 601 LSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDSNKTENRRITHISAEQK 660
LSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDSNKTENRRITHISAEQK
Sbjct: 601 LSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDSNKTENRRITHISAEQK 660
Query: 661 RRFNIKLGFDTLHGLVSTLSAQPSLKERAGLQEEAQQLRDEIEELNAAINLCQQQLPATG 720
RRFNIKLGFDTLHGLVSTLSAQPSLKERAGLQEEAQQLRDEIEELNAAINLCQQQLPATG
Sbjct: 661 RRFNIKLGFDTLHGLVSTLSAQPSLKERAGLQEEAQQLRDEIEELNAAINLCQQQLPATG 720
Query: 721 VPITHQRFDQMRDMFDDYVRTRTLHNWKFWVFSILIRPLFESFNGMVSTASVHTLRQTSL 780
VPITHQRFDQMRDMFDDYVRTRTLHNWKFWVFSILIRPLFESFNGMVSTASVHTLRQTSL
Sbjct: 721 VPITHQRFDQMRDMFDDYVRTRTLHNWKFWVFSILIRPLFESFNGMVSTASVHTLRQTSL 780
Query: 781 AWLDQYCSLPALRPTVLNSLRQLGTSTSILTDPGRIPEQATRAVTEGTLGKPL 833
AWLDQYCSLPALRPTVLNSLRQLGTSTSILTDPGRIPEQATRAVTEGTLGKPL
Sbjct: 781 AWLDQYCSLPALRPTVLNSLRQLGTSTSILTDPGRIPEQATRAVTEGTLGKPL 833
>gi|14602439 Williams Beuren syndrome chromosome region 14 isoform
delta [Homo sapiens]
Length = 831
Score = 1710 bits (4428), Expect = 0.0
Identities = 831/833 (99%), Positives = 831/833 (99%), Gaps = 2/833 (0%)
Query: 1 MAGALAGLAAGLQVPRVAPSPDSDSDTDSEDPSLRRSAGGLLRSQVIHSGHFMVSSPHSD 60
MAGALAGLAAGLQVPRVAPSPDSDSDTDSEDPSLRRSAGGLLRSQVIHSGHFMVSSPHSD
Sbjct: 1 MAGALAGLAAGLQVPRVAPSPDSDSDTDSEDPSLRRSAGGLLRSQVIHSGHFMVSSPHSD 60
Query: 61 SLPRRRDQEGSVGPSDFGPRSIDPTLTRLFECLSLAYSGKLVSPKWKNFKGLKLLCRDKI 120
SLPRRRDQEGSVGPSDFGPRSIDPTLTRLFECLSLAYSGKLVSPKWKNFKGLKLLCRDKI
Sbjct: 61 SLPRRRDQEGSVGPSDFGPRSIDPTLTRLFECLSLAYSGKLVSPKWKNFKGLKLLCRDKI 120
Query: 121 RLNNAIWRAWYIQYVKRRKSPVCGFVTPLQGPEADAHRKPEAVVLEGNYWKRRIEVVMRE 180
RLNNAIWRAWYIQYVKRRKSPVCGFVTPLQGPEADAHRKPEAVVLEGNYWKRRIEVVMRE
Sbjct: 121 RLNNAIWRAWYIQYVKRRKSPVCGFVTPLQGPEADAHRKPEAVVLEGNYWKRRIEVVMRE 180
Query: 181 YHKWRIYYKKRLRKPSREDDLLAPKQAEGRWPPPEQWCKQLFSSVVPVLLGDPEEEPGGR 240
YHKWRIYYKKRLRKPSREDDLLAPKQAEGRWPPPEQWCKQLFSSVVPVLLGDPEEEPGGR
Sbjct: 181 YHKWRIYYKKRLRKPSREDDLLAPKQAEGRWPPPEQWCKQLFSSVVPVLLGDPEEEPGGR 240
Query: 241 QLLDLNCFLSDISDTLFTMTQSGPSPLQLPPEDAYVGNADMIQPDLTPLQPSLDDFMDIS 300
QLLDLNCFLSDISDTLFTMTQSGPSPLQLPPEDAYVGNADMIQPDLTPLQPSLDDFMDIS
Sbjct: 241 QLLDLNCFLSDISDTLFTMTQSGPSPLQLPPEDAYVGNADMIQPDLTPLQPSLDDFMDIS 300
Query: 301 DFFTNSRLPQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARN 360
DFFTNSRLPQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARN
Sbjct: 301 DFFTNSRLPQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARN 360
Query: 361 SCPGPLDSSAFLSSDFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAP 420
SCPGPLDSSAFLSSDFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAP
Sbjct: 361 SCPGPLDSSAFLSSDFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAP 420
Query: 421 PTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYS 480
PTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYS
Sbjct: 421 PTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYS 480
Query: 481 EPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQA 540
EPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQA
Sbjct: 481 EPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQA 540
Query: 541 LEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAER 600
LEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAER
Sbjct: 541 LEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAER 600
Query: 601 LSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDSNKTENRRITHISAEQK 660
LSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDSNK NRRITHISAEQK
Sbjct: 601 LSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDSNK--NRRITHISAEQK 658
Query: 661 RRFNIKLGFDTLHGLVSTLSAQPSLKERAGLQEEAQQLRDEIEELNAAINLCQQQLPATG 720
RRFNIKLGFDTLHGLVSTLSAQPSLKERAGLQEEAQQLRDEIEELNAAINLCQQQLPATG
Sbjct: 659 RRFNIKLGFDTLHGLVSTLSAQPSLKERAGLQEEAQQLRDEIEELNAAINLCQQQLPATG 718
Query: 721 VPITHQRFDQMRDMFDDYVRTRTLHNWKFWVFSILIRPLFESFNGMVSTASVHTLRQTSL 780
VPITHQRFDQMRDMFDDYVRTRTLHNWKFWVFSILIRPLFESFNGMVSTASVHTLRQTSL
Sbjct: 719 VPITHQRFDQMRDMFDDYVRTRTLHNWKFWVFSILIRPLFESFNGMVSTASVHTLRQTSL 778
Query: 781 AWLDQYCSLPALRPTVLNSLRQLGTSTSILTDPGRIPEQATRAVTEGTLGKPL 833
AWLDQYCSLPALRPTVLNSLRQLGTSTSILTDPGRIPEQATRAVTEGTLGKPL
Sbjct: 779 AWLDQYCSLPALRPTVLNSLRQLGTSTSILTDPGRIPEQATRAVTEGTLGKPL 831
>gi|14602433 Williams Beuren syndrome chromosome region 14 isoform
alpha [Homo sapiens]
Length = 852
Score = 1707 bits (4421), Expect = 0.0
Identities = 833/852 (97%), Positives = 833/852 (97%), Gaps = 19/852 (2%)
Query: 1 MAGALAGLAAGLQVPRVAPSPDSDSDTDSEDPSLRRSAGGLLRSQVIHSGHFMVSSPHSD 60
MAGALAGLAAGLQVPRVAPSPDSDSDTDSEDPSLRRSAGGLLRSQVIHSGHFMVSSPHSD
Sbjct: 1 MAGALAGLAAGLQVPRVAPSPDSDSDTDSEDPSLRRSAGGLLRSQVIHSGHFMVSSPHSD 60
Query: 61 SLPRRRDQEGSVGPSDFGPRSIDPTLTRLFECLSLAYSGKLVSPKWKNFKGLKLLCRDKI 120
SLPRRRDQEGSVGPSDFGPRSIDPTLTRLFECLSLAYSGKLVSPKWKNFKGLKLLCRDKI
Sbjct: 61 SLPRRRDQEGSVGPSDFGPRSIDPTLTRLFECLSLAYSGKLVSPKWKNFKGLKLLCRDKI 120
Query: 121 RLNNAIWRAWYIQYVKRRKSPVCGFVTPLQGPEADAHRKPEAVVLEGNYWKRRIEVVMRE 180
RLNNAIWRAWYIQYVKRRKSPVCGFVTPLQGPEADAHRKPEAVVLEGNYWKRRIEVVMRE
Sbjct: 121 RLNNAIWRAWYIQYVKRRKSPVCGFVTPLQGPEADAHRKPEAVVLEGNYWKRRIEVVMRE 180
Query: 181 YHKWRIYYKKRLRKPSREDDLLAPKQAEGRWPPPEQWCKQLFSSVVPVLLGDPEEEPGGR 240
YHKWRIYYKKRLRKPSREDDLLAPKQAEGRWPPPEQWCKQLFSSVVPVLLGDPEEEPGGR
Sbjct: 181 YHKWRIYYKKRLRKPSREDDLLAPKQAEGRWPPPEQWCKQLFSSVVPVLLGDPEEEPGGR 240
Query: 241 QLLDLNCFLSDISDTLFTMTQSGPSPLQLPPEDAYVGNADMIQPDLTPLQPSLDDFMDIS 300
QLLDLNCFLSDISDTLFTMTQSGPSPLQLPPEDAYVGNADMIQPDLTPLQPSLDDFMDIS
Sbjct: 241 QLLDLNCFLSDISDTLFTMTQSGPSPLQLPPEDAYVGNADMIQPDLTPLQPSLDDFMDIS 300
Query: 301 DFFTNSRLPQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARN 360
DFFTNSRLPQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARN
Sbjct: 301 DFFTNSRLPQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARN 360
Query: 361 SCPGPLDSSAFLSSDFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAP 420
SCPGPLDSSAFLSSDFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAP
Sbjct: 361 SCPGPLDSSAFLSSDFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAP 420
Query: 421 PTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYS 480
PTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYS
Sbjct: 421 PTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYS 480
Query: 481 EPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQA 540
EPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQA
Sbjct: 481 EPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQA 540
Query: 541 LEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAER 600
LEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAER
Sbjct: 541 LEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAER 600
Query: 601 LSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDSNKTENRRITHISAEQK 660
LSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDSNKTENRRITHISAEQK
Sbjct: 601 LSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDSNKTENRRITHISAEQK 660
Query: 661 RRFNIKLGFDTLHGLVSTLSAQPSLK-------------------ERAGLQEEAQQLRDE 701
RRFNIKLGFDTLHGLVSTLSAQPSLK ERAGLQEEAQQLRDE
Sbjct: 661 RRFNIKLGFDTLHGLVSTLSAQPSLKVSKATTLQKTAEYILMLQQERAGLQEEAQQLRDE 720
Query: 702 IEELNAAINLCQQQLPATGVPITHQRFDQMRDMFDDYVRTRTLHNWKFWVFSILIRPLFE 761
IEELNAAINLCQQQLPATGVPITHQRFDQMRDMFDDYVRTRTLHNWKFWVFSILIRPLFE
Sbjct: 721 IEELNAAINLCQQQLPATGVPITHQRFDQMRDMFDDYVRTRTLHNWKFWVFSILIRPLFE 780
Query: 762 SFNGMVSTASVHTLRQTSLAWLDQYCSLPALRPTVLNSLRQLGTSTSILTDPGRIPEQAT 821
SFNGMVSTASVHTLRQTSLAWLDQYCSLPALRPTVLNSLRQLGTSTSILTDPGRIPEQAT
Sbjct: 781 SFNGMVSTASVHTLRQTSLAWLDQYCSLPALRPTVLNSLRQLGTSTSILTDPGRIPEQAT 840
Query: 822 RAVTEGTLGKPL 833
RAVTEGTLGKPL
Sbjct: 841 RAVTEGTLGKPL 852
>gi|14602437 Williams Beuren syndrome chromosome region 14 isoform
gamma [Homo sapiens]
Length = 850
Score = 1698 bits (4398), Expect = 0.0
Identities = 831/852 (97%), Positives = 831/852 (97%), Gaps = 21/852 (2%)
Query: 1 MAGALAGLAAGLQVPRVAPSPDSDSDTDSEDPSLRRSAGGLLRSQVIHSGHFMVSSPHSD 60
MAGALAGLAAGLQVPRVAPSPDSDSDTDSEDPSLRRSAGGLLRSQVIHSGHFMVSSPHSD
Sbjct: 1 MAGALAGLAAGLQVPRVAPSPDSDSDTDSEDPSLRRSAGGLLRSQVIHSGHFMVSSPHSD 60
Query: 61 SLPRRRDQEGSVGPSDFGPRSIDPTLTRLFECLSLAYSGKLVSPKWKNFKGLKLLCRDKI 120
SLPRRRDQEGSVGPSDFGPRSIDPTLTRLFECLSLAYSGKLVSPKWKNFKGLKLLCRDKI
Sbjct: 61 SLPRRRDQEGSVGPSDFGPRSIDPTLTRLFECLSLAYSGKLVSPKWKNFKGLKLLCRDKI 120
Query: 121 RLNNAIWRAWYIQYVKRRKSPVCGFVTPLQGPEADAHRKPEAVVLEGNYWKRRIEVVMRE 180
RLNNAIWRAWYIQYVKRRKSPVCGFVTPLQGPEADAHRKPEAVVLEGNYWKRRIEVVMRE
Sbjct: 121 RLNNAIWRAWYIQYVKRRKSPVCGFVTPLQGPEADAHRKPEAVVLEGNYWKRRIEVVMRE 180
Query: 181 YHKWRIYYKKRLRKPSREDDLLAPKQAEGRWPPPEQWCKQLFSSVVPVLLGDPEEEPGGR 240
YHKWRIYYKKRLRKPSREDDLLAPKQAEGRWPPPEQWCKQLFSSVVPVLLGDPEEEPGGR
Sbjct: 181 YHKWRIYYKKRLRKPSREDDLLAPKQAEGRWPPPEQWCKQLFSSVVPVLLGDPEEEPGGR 240
Query: 241 QLLDLNCFLSDISDTLFTMTQSGPSPLQLPPEDAYVGNADMIQPDLTPLQPSLDDFMDIS 300
QLLDLNCFLSDISDTLFTMTQSGPSPLQLPPEDAYVGNADMIQPDLTPLQPSLDDFMDIS
Sbjct: 241 QLLDLNCFLSDISDTLFTMTQSGPSPLQLPPEDAYVGNADMIQPDLTPLQPSLDDFMDIS 300
Query: 301 DFFTNSRLPQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARN 360
DFFTNSRLPQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARN
Sbjct: 301 DFFTNSRLPQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARN 360
Query: 361 SCPGPLDSSAFLSSDFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAP 420
SCPGPLDSSAFLSSDFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAP
Sbjct: 361 SCPGPLDSSAFLSSDFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAP 420
Query: 421 PTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYS 480
PTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYS
Sbjct: 421 PTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYS 480
Query: 481 EPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQA 540
EPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQA
Sbjct: 481 EPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQA 540
Query: 541 LEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAER 600
LEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAER
Sbjct: 541 LEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAER 600
Query: 601 LSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDSNKTENRRITHISAEQK 660
LSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDSNK NRRITHISAEQK
Sbjct: 601 LSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDSNK--NRRITHISAEQK 658
Query: 661 RRFNIKLGFDTLHGLVSTLSAQPSLK-------------------ERAGLQEEAQQLRDE 701
RRFNIKLGFDTLHGLVSTLSAQPSLK ERAGLQEEAQQLRDE
Sbjct: 659 RRFNIKLGFDTLHGLVSTLSAQPSLKVSKATTLQKTAEYILMLQQERAGLQEEAQQLRDE 718
Query: 702 IEELNAAINLCQQQLPATGVPITHQRFDQMRDMFDDYVRTRTLHNWKFWVFSILIRPLFE 761
IEELNAAINLCQQQLPATGVPITHQRFDQMRDMFDDYVRTRTLHNWKFWVFSILIRPLFE
Sbjct: 719 IEELNAAINLCQQQLPATGVPITHQRFDQMRDMFDDYVRTRTLHNWKFWVFSILIRPLFE 778
Query: 762 SFNGMVSTASVHTLRQTSLAWLDQYCSLPALRPTVLNSLRQLGTSTSILTDPGRIPEQAT 821
SFNGMVSTASVHTLRQTSLAWLDQYCSLPALRPTVLNSLRQLGTSTSILTDPGRIPEQAT
Sbjct: 779 SFNGMVSTASVHTLRQTSLAWLDQYCSLPALRPTVLNSLRQLGTSTSILTDPGRIPEQAT 838
Query: 822 RAVTEGTLGKPL 833
RAVTEGTLGKPL
Sbjct: 839 RAVTEGTLGKPL 850
>gi|111955326 MLX interacting protein [Homo sapiens]
Length = 919
Score = 523 bits (1348), Expect = e-148
Identities = 372/940 (39%), Positives = 492/940 (52%), Gaps = 157/940 (16%)
Query: 11 GLQVPRVAPSPDSDSDTDSEDPSLRRSAGGLL------------------------RSQV 46
G QV + D D+D+++PS ++G R Q+
Sbjct: 17 GRQVLLKPQVSEDDDDSDTDEPSPPPASGAATPARAHASAAPPPPRAGPGREEPPRRQQI 76
Query: 47 IHSGHFMVSSPHSDSLPRR----------RDQEGSVGPSDFGPRSIDPTLTRLFECLSLA 96
IHSGHFMVSSPH + P++ Q S G + SID +LT+LFEC++LA
Sbjct: 77 IHSGHFMVSSPHREHPPKKGYDFDTVNKQTCQTYSFGKTSSCHLSIDASLTKLFECMTLA 136
Query: 97 YSGKLVSPKWKNFKGLKLLCRDKIRLNNAIWRAWYIQYVKRRKSPVCGFVTPLQGP-EAD 155
YSGKLVSPKWKNFKGLKL RDKIRLNNAIWRAWY+QY+++RK+PVC FVTPL G + D
Sbjct: 137 YSGKLVSPKWKNFKGLKLQWRDKIRLNNAIWRAWYMQYLEKRKNPVCHFVTPLDGSVDVD 196
Query: 156 AHRKPEAVVLEGNYWKRRIEVVMREYHKWRIYYKKRLRKPSREDDLLAPKQAEGRWPPPE 215
HR+PEA+ EG YWK RIE+V+REYHKWR Y+KKRL++ +++DL + Q +
Sbjct: 197 EHRRPEAITTEGKYWKSRIEIVIREYHKWRTYFKKRLQQ-HKDEDLSSLVQDDDML---- 251
Query: 216 QWCKQLFSSVVPVLLGDPEEEPGGRQLLDLNCFLSDISDTLF-TMTQSGPSPLQLPPEDA 274
W K PV + EE+P LLD + +S+ SDTLF T++ P P E A
Sbjct: 252 YWHKHGDGWKTPVPM---EEDP----LLDTDMLMSEFSDTLFSTLSSHQPVAWPNPREIA 304
Query: 275 YVGNADMIQPDLTPLQPSLDDFMD----ISDFFTNSRL---PQPPMPSNFPEP-PSFSPV 326
++GNADMIQP L PLQP+LD FMD D F++SR P ++ P P P+ P
Sbjct: 305 HLGNADMIQPGLIPLQPNLD-FMDTFEPFQDLFSSSRSIFGSMLPASASAPVPDPNNPPA 363
Query: 327 VDSLFSSGTLGPEV--------PPASSAMTHLSGHSRLQARNSCPGPLDSSAFLSSDFLL 378
+S+ + L P V PP + ++ H+ C + ++ F+
Sbjct: 364 QESILPTTAL-PTVSLPDSLIAPPTAPSLAHMD-------EQGC----EHTSRTEDPFIQ 411
Query: 379 PEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPP-----FPPMAPPTALLQEE--PLF 431
P D P PP VP P L P +P L P P PP P + PP L P F
Sbjct: 412 PTDFGPSEPPLSVPQPFL---PVFTMPLLSPSPAPPPISPVLPLVPPPATALNPPAPPTF 468
Query: 432 SPRFPFPTVPPAPGVSPLPAPAAF----PPTPQSV----------PSPAPTPFPIELLPL 477
F V AP V A A P T S P+P+ P + L P+
Sbjct: 469 HQPQKFAGVNKAPSVITHTASATLTHDAPATTFSQSQGLVITTHHPAPSAAPCGLALSPV 528
Query: 478 GYSEPAFGPCFSMPR------GKP---------PAPSPRGQKASPPTLAPATAS--PPTT 520
P F P+ G+P P P P +APA S P
Sbjct: 529 T-RPPQPRLTFVHPKPVSLTGGRPKQPHKIVPAPKPEPVSLVLKNARIAPAAFSGQPQAV 587
Query: 521 AGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRP 580
++ P + + A+ Q+ + + + R+PG VPEF + L P
Sbjct: 588 IMTSGPLKREGMLASTVSQS-NVVIAPAAIARAPG-----VPEFHSSILVTDLGHGTSSP 641
Query: 581 PPGPATLAPSRPLLVPKAERLSPPAPSGSER-RLSGDLSSMPGPGTLSVRVSPPQPILSR 639
P + L PS P + P GS + ++G P G S S P S
Sbjct: 642 PAPVSRLFPSTAQ-DPLGKGEQVPLHGGSPQVTVTGPSRDCPNSGQASPCASEQSP--SP 698
Query: 640 GRPDSNKT-----------ENRRITHISAEQKRRFNIKLGFDTLHGLVSTLSAQPS---- 684
P +N + +NR++ HISAEQKRRFNIK+ FD L+ L+S S S
Sbjct: 699 QSPQNNCSGKSDPKNVAALKNRQMKHISAEQKRRFNIKMCFDMLNSLISNNSKLTSHAIT 758
Query: 685 -----------LKERAGLQEEAQQLRDEIEELNAAINLCQQQLPATGVPITHQRFDQMRD 733
+ER +QEEA++LR+EIEELNA I CQQ LPATGVP+T ++FD M+D
Sbjct: 759 LQKTVEYITKLQQERGQMQEEARRLREEIEELNATIISCQQLLPATGVPVTRRQFDHMKD 818
Query: 734 MFDDYVRTRTLHNWKFWVFSILIRPLFESFNGMVSTASVHTLRQTSLAWLDQYCSLPALR 793
MFD+YV+TRTL NWKFW+FSI+I+PLFESF GMVST+S+ L +T+L+WLDQ+CSLP LR
Sbjct: 819 MFDEYVKTRTLQNWKFWIFSIIIKPLFESFKGMVSTSSLEELHRTALSWLDQHCSLPILR 878
Query: 794 PTVLNSLRQLGTSTSILTDPGRIPEQATRAVTEGTLGKPL 833
P VL++LRQL TSTSILTDP ++PEQA++AVT +GK L
Sbjct: 879 PMVLSTLRQLSTSTSILTDPAQLPEQASKAVTR--IGKRL 916
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 105 bits (262), Expect = 2e-22
Identities = 120/405 (29%), Positives = 151/405 (37%), Gaps = 50/405 (12%)
Query: 252 ISDTLFTMTQSGPSPLQLPPEDAYVGNADMIQPDLTPLQPSL--DDFMDISDFFTNSRLP 309
I L T + P LQ PP A + P L L PSL S T L
Sbjct: 508 IMPPLETQSSLAPPSLQTPP-------ASLTTPPLENL-PSLAPPPLQTASAPLTTPHLE 559
Query: 310 QPPMPSNFP--EPPS--FSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCP-G 364
PP P+ P PPS +P ++ S T P+ PPA ++ LQ S P
Sbjct: 560 TPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPP-------LQGLPSPPLS 612
Query: 365 PLDSSAFLSSDFL-LPEDPKPRLPPPPVPPPL--LHYPPPAKVPGLE------PCPPPPF 415
PL + + L LP P P PP PPL L P P L P PPP
Sbjct: 613 PLATPPPQAPPXLALPPLQAP--PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPS 670
Query: 416 PPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELL 475
PP+ P + P+ P PP+ PL P + P +P PS P P
Sbjct: 671 PPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQA---- 726
Query: 476 PLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAA 535
P P +P P +P PP + P A+PP + P + A
Sbjct: 727 ----PPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLA 782
Query: 536 KPEQALEPPLVSSTLLRSPGSPQE---TVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRP 592
KP P L + L P P P P LP +P TP PP P LA P
Sbjct: 783 KPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATP--PPQAPPVLA--AP 838
Query: 593 LL-VPKAERLSPPAPSGSERRLSGDLSSMPGPG-TLSVRVSPPQP 635
LL VP + SP + G +S+ GP TL++ PP P
Sbjct: 839 LLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPP 883
Score = 92.0 bits (227), Expect = 2e-18
Identities = 109/356 (30%), Positives = 149/356 (41%), Gaps = 47/356 (13%)
Query: 267 LQLPPEDAYVGNADMIQPDLTPLQPSLDDFMDISDFFTNSRLPQPPMPSNFP--EPPSFS 324
LQ PP + + +P + F+ +S T + L P P++ P PP +
Sbjct: 400 LQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQA 459
Query: 325 PVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDSSAFLSSDFLLPEDPKP 384
P+ SL +S L + PA S ++ LQA +S A LSS + P + +
Sbjct: 460 PL--SLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASH-SPQAPLSSLIMPPLETQS 516
Query: 385 RLPPPPV--PPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPP 442
L PP + PP L PP +P L P PP+ +A PL +P PP
Sbjct: 517 SLAPPSLQTPPASLTTPPLENLPSLAP------PPLQTASA-----PLTTPHLE---TPP 562
Query: 443 APGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYSEPAFGPCFSMP--RGKPPAP-S 499
P PL AP P+P + P P TP I P P P + P +G P P S
Sbjct: 563 CPAPCPLQAP----PSPLTTP-PPETPSSIATPP-----PQAPPALASPPLQGLPSPPLS 612
Query: 500 PRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQE 559
P PP P A PP A + P L A P P ++ LL++P SP
Sbjct: 613 PLA--TPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQ-APNALAVHLLQAPFSPPP 669
Query: 560 TVPEFPCTFLPP-----TPAPTPPRPPPGPATLAPSRPLLVPKAERLSPP-APSGS 609
+ P F PP +P+ TPP P P+ AP PL VP + SPP +PS +
Sbjct: 670 S-PPVQAPFSPPASPPVSPSATPPSQAP-PSLAAP--PLQVPPSPPASPPMSPSAT 721
Score = 72.8 bits (177), Expect = 1e-12
Identities = 102/380 (26%), Positives = 127/380 (33%), Gaps = 71/380 (18%)
Query: 252 ISDTLFTMTQSGPS----PLQLPPEDAYVGNADMIQPDLTPLQPSLDDFMDISDFFTNSR 307
+S + +Q+ PS PLQ+PP P P+ PS
Sbjct: 685 VSPSATPPSQAPPSLAAPPLQVPPSP----------PASPPMSPSATPPPQAPPPLAAPP 734
Query: 308 LPQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLD 367
L PP P P P SP S T P VPP +A LQ S P L
Sbjct: 735 LQVPPSP---PASPPMSP-------SATPPPRVPPLLAAPP-------LQVPPSPPASLP 777
Query: 368 SSAFLSSDFLLPEDPKPRLPPPPVPPPLLHYP-PPAKVPGLEPCPPPPFPPMAP-PTALL 425
S P P+ PP PPL P PPA PG P P PM+P T
Sbjct: 778 MSPLAK--------PPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPP 829
Query: 426 QEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYSEPAFG 485
Q P+ + P VPP+P SP PPTP S + + L P
Sbjct: 830 QAPPVLAA--PLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAP--------- 878
Query: 486 PCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEPPL 545
G PP PS + S P A ++A S L + + A PP
Sbjct: 879 -------GPPPPPS---RSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPP 928
Query: 546 VSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAERLSPPA 605
+ P + P P F AP P P GP + + + + PA
Sbjct: 929 DAELAACHPAA-WSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPA 987
Query: 606 PSGSERRLSGDLSSMPGPGT 625
P G L P PGT
Sbjct: 988 P--------GALDPGPSPGT 999
Score = 69.7 bits (169), Expect = 1e-11
Identities = 105/442 (23%), Positives = 134/442 (30%), Gaps = 117/442 (26%)
Query: 304 TNSRLPQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCP 363
T LP+P PS P PP+ P +S E PA+ G + A S
Sbjct: 185 TEVGLPRPA-PSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLS 243
Query: 364 G---PLDSSAFLSSDF-------LLPEDPKPR----LPPPPVPPPLLHYPP--------P 401
PL S A P PKP+ L PP V PP P P
Sbjct: 244 SSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSP 303
Query: 402 AKVPG-----LEPCPPP------------PFPPMAPPTALLQEEPLFSPRFPFPTVPPAP 444
P P PPP P PP+A P L P P PPA
Sbjct: 304 LATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPAT 363
Query: 445 GVSPLPAPAAFPP--------------TPQSVPSPA--PTPFPIELLPLGYSEPAFGPCF 488
S P PP P S+ SP+ P P+ L L + P
Sbjct: 364 PPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTL 423
Query: 489 -------------------------SMPRGKPPAPSPRGQKASPP---TLAPATA--SPP 518
S P PP +P ASPP +L+PA + S P
Sbjct: 424 QATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSP 483
Query: 519 TTA------------GSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEF-- 564
T P + ++ + + +L PP + + P E +P
Sbjct: 484 LTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAP 543
Query: 565 ------------PCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAERLSPPAPSGSERR 612
P PP PAP P + PP P T P ++ P P
Sbjct: 544 PPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPE-----TPSSIATPPPQAPPAL 598
Query: 613 LSGDLSSMPGPGTLSVRVSPPQ 634
S L +P P + PPQ
Sbjct: 599 ASPPLQGLPSPPLSPLATPPPQ 620
Score = 44.7 bits (104), Expect = 4e-04
Identities = 67/247 (27%), Positives = 86/247 (34%), Gaps = 22/247 (8%)
Query: 377 LLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPP----------PPFPPMAPPTALLQ 426
L P P PPPPV P L A G +P P P A PT
Sbjct: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPT---- 80
Query: 427 EEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYSEPAFGP 486
S R P + PPA G AP A +P V SP PLG
Sbjct: 81 RSAGTSSRNP-ASRPPASGRGE-RAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISA 138
Query: 487 CFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEPPLV 546
++ RGK + K S + + T G+ +P + + AA E L P
Sbjct: 139 EETVARGK----ATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAP 194
Query: 547 SSTLLRSPGSPQETVPE-FPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAERLSPPA 605
S+ P+++V + P+PA RP G P+ L A LS PA
Sbjct: 195 SARPRPPTEGPRKSVSSASEHSTTEPSPA-ARRRPSAGGGLQRPASRSLSSSATPLSSPA 253
Query: 606 PSGSERR 612
SG R
Sbjct: 254 RSGPSAR 260
Score = 43.1 bits (100), Expect = 0.001
Identities = 56/234 (23%), Positives = 74/234 (31%), Gaps = 20/234 (8%)
Query: 417 PMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLP 476
P A LL P SPR P P P A V P + P E P
Sbjct: 17 PAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIP-ESAP 75
Query: 477 LGYSEPAFGPCFSMPRGKPPAPSPRGQKASP-------PTLAPATASPPTTAG------- 522
+ G P +PPA S RG++A P P +P AS T G
Sbjct: 76 RAGPTRSAGTSSRNPASRPPA-SGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGL 134
Query: 523 ---SNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTP-P 578
+ T A AL T +PG+P + P P P
Sbjct: 135 RISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAP 194
Query: 579 RPPPGPATLAPSRPLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSP 632
P P T P + + + P+P+ R +G P +LS +P
Sbjct: 195 SARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATP 248
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 102 bits (253), Expect = 2e-21
Identities = 109/359 (30%), Positives = 146/359 (40%), Gaps = 45/359 (12%)
Query: 309 PQPPMPSNFP--EPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPL 366
P P P PP +P ++ LGP +SS + S + LQ++ P L
Sbjct: 269 PSQPKPKGLQALRPPQVTPPRKD--AAPALGPL---SSSPLATPSPSAALQSQ--APPTL 321
Query: 367 DSSAFLSSDFLLPEDPKPRLPPPPVPPPLLH-YPPPAKVPGLEPCPPPPFPPMAPPTALL 425
++ SS P P PP P PP L P P P + P + + L
Sbjct: 322 PATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFL 381
Query: 426 QEEPLFSPRFPFPTVPPAPGVSPL---PAPAAFPP-TPQSVPSP-APTPFPIELLPLGYS 480
PL P P PPA + PL P+P A PP +P + PSP AP + LL +S
Sbjct: 382 PSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFS 441
Query: 481 EPAFGPC---FSMPRGKPPAPSPRGQKASPPTLA--------PATASPPTTAGSNNPCLT 529
P P FS P P +PS +PP+LA ASPP + + P
Sbjct: 442 PPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQA 501
Query: 530 QLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTF-----------LPPTPAPTPP 578
AA P Q +PP + L +P P + +P P +F LP +P TP
Sbjct: 502 PPPLAAPPLQLAKPPPQAPPALATP--PLQALPSPPASFPGQAPFSPSASLPMSPLATP- 558
Query: 579 RPPPGPATLAPSRPLL-VPKAERLSPPAPSGSERRLSGDLSSMPGPG-TLSVRVSPPQP 635
PP P LA PLL VP + SP + G +S+ GP TL++ PP P
Sbjct: 559 -PPQAPPVLA--APLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPP 614
Score = 89.7 bits (221), Expect = 1e-17
Identities = 116/401 (28%), Positives = 147/401 (36%), Gaps = 41/401 (10%)
Query: 264 PSPLQLPPEDAYVGNADMIQPDLTPLQPSLDDFMDISDFFTNSRLPQPPMPSNFPEPPSF 323
P PL P A + P TP + + T+S LP PP+ PP
Sbjct: 337 PLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQA 396
Query: 324 SPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDSSAF-------LSSDF 376
P +L P PPAS ++ L+ S QA N+ L + F + + F
Sbjct: 397 PP---ALALPPLQAPPSPPASPPLSPLATPSP-QAPNALAVHLLQAPFSPPPSPPVQAPF 452
Query: 377 LLPEDP--KPRLPPPPVPPPLLHYPP------PAKVPGLEP--CPPPPFPP--MAPPTAL 424
P P P PP PP L PP P P + P PPP PP APP L
Sbjct: 453 SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQL 512
Query: 425 LQEEPLFSPRFPFPTV-----PPA--PGVSPLPAPAAFPPTPQSVPSP-APTPFPIELLP 476
+ P P P + PPA PG +P A+ P +P + P P AP LL
Sbjct: 513 AKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQ 572
Query: 477 LGYSEPAFGPCFSMPRGKPPAPSPRGQKASPP-TLAPATASPPTTAGSNNPCLTQLLTAA 535
+ S PA P PR +PP P P + P TLA A PP + S + L+ A
Sbjct: 573 VPPSPPA-SPTLQAPR-RPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAG 630
Query: 536 KPEQALEPPLVSSTLLRSP--GSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPL 593
A P P G+ P+ P P PP AP PL
Sbjct: 631 HSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLA-FRGAPGAPL 689
Query: 594 LVPKAERLSPPAPSG--SERRLSGDLSSMPGPGTLSVRVSP 632
P A P + G + G S+ P PG L SP
Sbjct: 690 PWPPA--TGPGSADGLCTIYETEGPESATPAPGALDPGPSP 728
Score = 76.6 bits (187), Expect = 9e-14
Identities = 114/393 (29%), Positives = 138/393 (35%), Gaps = 81/393 (20%)
Query: 265 SPLQLPPEDAYVGNADMIQPDLTPLQ--PSLDDFMDISDFFTNSRLPQPP-------MPS 315
SPL PP A A L PLQ PS +S T S PQ P + +
Sbjct: 387 SPLATPPPQAPPALA------LPPLQAPPSPPASPPLSPLATPS--PQAPNALAVHLLQA 438
Query: 316 NFPEPPSFSPVVDSLFS---SGTLGPEVPPASSAMTHLSGHSRLQARNSCPG--PLDSSA 370
F PPS P V + FS S + P P S A L+ LQ S P P+ SA
Sbjct: 439 PFSPPPS--PPVQAPFSPPASPPVSPSATPPSQAPPSLAAPP-LQVPPSPPASPPMSPSA 495
Query: 371 FLSSDFLLPEDPKPRLPPPPVPPPL-LHYPPPAKVPGLE-------PCPPPPFPPMAP-- 420
P P+ PPP PPL L PPP P L P PP FP AP
Sbjct: 496 ----------TPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFS 545
Query: 421 PTALLQEEPLFSP--------RFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPI 472
P+A L PL +P P VPP+P SP PPTP S + +
Sbjct: 546 PSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTL 605
Query: 473 ELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLL 532
L P G PP PS + S P A ++A S L
Sbjct: 606 ALAP----------------GPPPPPS---RSPSSTLSGPDLAGHSSSATSTPEELRGYD 646
Query: 533 TAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRP 592
+ + A PP + P + P P F AP P P GP +
Sbjct: 647 SGPEGGAAASPPPDAELAACHPAA-WSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCT 705
Query: 593 LLVPKAERLSPPAPSGSERRLSGDLSSMPGPGT 625
+ + + PAP G L P PGT
Sbjct: 706 IYETEGPESATPAP--------GALDPGPSPGT 730
Score = 44.7 bits (104), Expect = 4e-04
Identities = 67/247 (27%), Positives = 86/247 (34%), Gaps = 22/247 (8%)
Query: 377 LLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPP----------PPFPPMAPPTALLQ 426
L P P PPPPV P L A G +P P P A PT
Sbjct: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPT---- 80
Query: 427 EEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYSEPAFGP 486
S R P + PPA G AP A +P V SP PLG
Sbjct: 81 RSAGTSSRNP-ASRPPASGRGE-RAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISA 138
Query: 487 CFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEPPLV 546
++ RGK + K S + + T G+ +P + + AA E L P
Sbjct: 139 EETVARGK----ATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAP 194
Query: 547 SSTLLRSPGSPQETVPE-FPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAERLSPPA 605
S+ P+++V + P+PA RP G P+ L A LS PA
Sbjct: 195 SARPRPPTEGPRKSVSSASEHSTTEPSPA-ARRRPSAGGGLQRPASRSLSSSATPLSSPA 253
Query: 606 PSGSERR 612
SG R
Sbjct: 254 RSGPSAR 260
Score = 44.3 bits (103), Expect = 5e-04
Identities = 63/223 (28%), Positives = 75/223 (33%), Gaps = 53/223 (23%)
Query: 448 PLPAPAAFPPTPQSVP----SPAPTPFPIELLPLGYSEPAFGPCFSMPRGKP-------- 495
P PAP+A P P P S A E P P+ G P +
Sbjct: 190 PRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPL 249
Query: 496 PAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEP---------PLV 546
+P+ G A APA S P G L A +P Q P PL
Sbjct: 250 SSPARSGPSARGTPRAPAHPSQPKPKG---------LQALRPPQVTPPRKDAAPALGPLS 300
Query: 547 SSTL--------LRSPGSPQETVPEFP------CTFLPPTP-APTPPRPPPGPATLAPSR 591
SS L L+S P T+P P C P P AP P PP TL PS
Sbjct: 301 SSPLATPSPSAALQSQAPP--TLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTL-PSP 357
Query: 592 PLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQ 634
P P S +P+ L S +P P + PPQ
Sbjct: 358 PATPPSQATTSLGSPT-----LQATHSFLPSPPLSPLATPPPQ 395
Score = 43.1 bits (100), Expect = 0.001
Identities = 56/234 (23%), Positives = 74/234 (31%), Gaps = 20/234 (8%)
Query: 417 PMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLP 476
P A LL P SPR P P P A V P + P E P
Sbjct: 17 PAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIP-ESAP 75
Query: 477 LGYSEPAFGPCFSMPRGKPPAPSPRGQKASP-------PTLAPATASPPTTAG------- 522
+ G P +PPA S RG++A P P +P AS T G
Sbjct: 76 RAGPTRSAGTSSRNPASRPPA-SGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGL 134
Query: 523 ---SNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTP-P 578
+ T A AL T +PG+P + P P P
Sbjct: 135 RISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAP 194
Query: 579 RPPPGPATLAPSRPLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSP 632
P P T P + + + P+P+ R +G P +LS +P
Sbjct: 195 SARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATP 248
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 101 bits (252), Expect = 2e-21
Identities = 113/357 (31%), Positives = 144/357 (40%), Gaps = 55/357 (15%)
Query: 325 PVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDSSAFLSSDFLLP-EDPK 383
P SL SS T P PA S + G R A S P P A P +D
Sbjct: 228 PASRSLSSSAT--PLSSPARSGPS-ARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAA 284
Query: 384 PRLPP---PPVPPPLLHYPP-PAKVPGLEPCPPPPFPPMAPPT------------ALLQE 427
P L P P+ P PP P+ P L+ P PP P + T + L
Sbjct: 285 PALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPS 344
Query: 428 EPLFSPRFPFPTVPPAPGVSPL---PAPAAFPP-TPQSVPSP-APTPFPIELLPLGYSEP 482
PL P P PPA + PL P+P A PP +P + PSP AP + LL +S P
Sbjct: 345 PPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP 404
Query: 483 AFGPC---FSMPRGKPPAPSPRGQKASPPTLA--------PATASPPTTAGSNNPCLTQL 531
P FS P P +PS +PP+LA ASPP + + P
Sbjct: 405 PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP 464
Query: 532 LTAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTF-----------LPPTPAPTPPRP 580
AA P Q +PP + L +P P + +P P +F LP +P TP P
Sbjct: 465 PLAAPPLQLAKPPPQAPPALATP--PLQALPSPPASFPGQAPFSPSASLPMSPLATP--P 520
Query: 581 PPGPATLAPSRPLL-VPKAERLSPPAPSGSERRLSGDLSSMPGPG-TLSVRVSPPQP 635
P P LA PLL VP + SP + G +S+ GP TL++ PP P
Sbjct: 521 PQAPPVLA--APLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPP 575
Score = 89.7 bits (221), Expect = 1e-17
Identities = 116/401 (28%), Positives = 147/401 (36%), Gaps = 41/401 (10%)
Query: 264 PSPLQLPPEDAYVGNADMIQPDLTPLQPSLDDFMDISDFFTNSRLPQPPMPSNFPEPPSF 323
PSP P A + P TP + + T+S LP PP+ PP
Sbjct: 298 PSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQA 357
Query: 324 SPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDSSAF-------LSSDF 376
P +L P PPAS ++ L+ S QA N+ L + F + + F
Sbjct: 358 PP---ALALPPLQAPPSPPASPPLSPLATPSP-QAPNALAVHLLQAPFSPPPSPPVQAPF 413
Query: 377 LLPEDP--KPRLPPPPVPPPLLHYPP------PAKVPGLEP--CPPPPFPP--MAPPTAL 424
P P P PP PP L PP P P + P PPP PP APP L
Sbjct: 414 SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQL 473
Query: 425 LQEEPLFSPRFPFPTV-----PPA--PGVSPLPAPAAFPPTPQSVPSP-APTPFPIELLP 476
+ P P P + PPA PG +P A+ P +P + P P AP LL
Sbjct: 474 AKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQ 533
Query: 477 LGYSEPAFGPCFSMPRGKPPAPSPRGQKASPP-TLAPATASPPTTAGSNNPCLTQLLTAA 535
+ S PA P PR +PP P P + P TLA A PP + S + L+ A
Sbjct: 534 VPPSPPA-SPTLQAPR-RPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAG 591
Query: 536 KPEQALEPPLVSSTLLRSP--GSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPL 593
A P P G+ P+ P P PP AP PL
Sbjct: 592 HSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLA-FRGAPGAPL 650
Query: 594 LVPKAERLSPPAPSG--SERRLSGDLSSMPGPGTLSVRVSP 632
P A P + G + G S+ P PG L SP
Sbjct: 651 PWPPA--TGPGSADGLCTIYETEGPESATPAPGALDPGPSP 689
Score = 76.6 bits (187), Expect = 9e-14
Identities = 114/393 (29%), Positives = 138/393 (35%), Gaps = 81/393 (20%)
Query: 265 SPLQLPPEDAYVGNADMIQPDLTPLQ--PSLDDFMDISDFFTNSRLPQPP-------MPS 315
SPL PP A A L PLQ PS +S T S PQ P + +
Sbjct: 348 SPLATPPPQAPPALA------LPPLQAPPSPPASPPLSPLATPS--PQAPNALAVHLLQA 399
Query: 316 NFPEPPSFSPVVDSLFS---SGTLGPEVPPASSAMTHLSGHSRLQARNSCPG--PLDSSA 370
F PPS P V + FS S + P P S A L+ LQ S P P+ SA
Sbjct: 400 PFSPPPS--PPVQAPFSPPASPPVSPSATPPSQAPPSLAAPP-LQVPPSPPASPPMSPSA 456
Query: 371 FLSSDFLLPEDPKPRLPPPPVPPPL-LHYPPPAKVPGLE-------PCPPPPFPPMAP-- 420
P P+ PPP PPL L PPP P L P PP FP AP
Sbjct: 457 ----------TPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFS 506
Query: 421 PTALLQEEPLFSP--------RFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPI 472
P+A L PL +P P VPP+P SP PPTP S + +
Sbjct: 507 PSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTL 566
Query: 473 ELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLL 532
L P G PP PS + S P A ++A S L
Sbjct: 567 ALAP----------------GPPPPPS---RSPSSTLSGPDLAGHSSSATSTPEELRGYD 607
Query: 533 TAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRP 592
+ + A PP + P + P P F AP P P GP +
Sbjct: 608 SGPEGGAAASPPPDAELAACHPAA-WSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCT 666
Query: 593 LLVPKAERLSPPAPSGSERRLSGDLSSMPGPGT 625
+ + + PAP G L P PGT
Sbjct: 667 IYETEGPESATPAP--------GALDPGPSPGT 691
Score = 45.1 bits (105), Expect = 3e-04
Identities = 86/333 (25%), Positives = 103/333 (30%), Gaps = 77/333 (23%)
Query: 377 LLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPP----------PPFPPMAPPTALLQ 426
L P P PPPPV P L A G +P P P A PT
Sbjct: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTR--T 82
Query: 427 EEPLFSPRF----PFPTVPPAPGVSPLPAPAAFPPTP-----------QSVPSPAPTPFP 471
P S R P P P SP A P P ++V T P
Sbjct: 83 SRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAP 142
Query: 472 -IELLPLGYSEPAFGPCFSMP------------------------RGKPPAPSPRGQKAS 506
L G GP P R +PP PR +S
Sbjct: 143 KRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSS 202
Query: 507 P---PTLAPATAS---PPTTAGSNNPCLTQLLTAAKP--EQALEPPLVSSTLLRSPGSPQ 558
T P+ A+ P G P L ++A P A P T R+P P
Sbjct: 203 ASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGT-PRAPAHPS 261
Query: 559 ETVPEFPCTFLPPTPAPTPPRPPPGPATLAP--SRPLLVPKAERLSPPAPSGSERRLSGD 616
+ P+ P P TPPR PA L P S PL P +PP+PS
Sbjct: 262 QPKPKGLQALRP--PQVTPPRKDAAPA-LGPLSSSPLATPSPS--APPSPSAPP-----S 311
Query: 617 LSSMPGPGTLSVRVSPPQPILSRGRPDSNKTEN 649
L ++P P P Q S G P T +
Sbjct: 312 LQTLPSPPA----TPPSQATTSLGSPTLQATHS 340
Score = 39.7 bits (91), Expect = 0.012
Identities = 56/234 (23%), Positives = 74/234 (31%), Gaps = 29/234 (12%)
Query: 417 PMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLP 476
P A LL P SPR P P P A V P + P
Sbjct: 17 PAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIP----- 71
Query: 477 LGYSEPAFGPCFSMPRGKPPAPSPRGQKASP-------PTLAPATASPPTTAG------- 522
S P GP + +PPA S RG++A P P +P AS T G
Sbjct: 72 --ESAPRAGPTRT---SRPPA-SGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGL 125
Query: 523 ---SNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTP-P 578
+ T A AL T +PG+P + P P P
Sbjct: 126 RISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAP 185
Query: 579 RPPPGPATLAPSRPLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSP 632
P P T P + + + P+P+ R +G P +LS +P
Sbjct: 186 SARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATP 239
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 95.5 bits (236), Expect = 2e-19
Identities = 124/420 (29%), Positives = 149/420 (35%), Gaps = 66/420 (15%)
Query: 268 QLPPEDAYVGNADMIQPDLTPLQPSLDDFM-----DISDFFTNSRLPQPPMPSNFPEPPS 322
Q PP + + +A QP P +F +S F NS N P PP
Sbjct: 809 QPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNS--------CNIPSPPP 860
Query: 323 FSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDSSAFLSSDFLLPEDP 382
P +S S LG VPP + ++ + P PL + L P P
Sbjct: 861 L-PCTESSSSMPGLGM-VPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPP----PPPP 914
Query: 383 KPRL---PPPPVP-------PPL--LHYPPPAKVPGLEPCPPPPFP----PMAPP---TA 423
P PPPP+P PPL PPP +PG PPPP P P+ PP
Sbjct: 915 LPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAG 974
Query: 424 LLQEEPLFSPRFPFPTVPPAPGVS---PLPAPAAFPPTPQSVPS---PAPTPFPIELLPL 477
+ PL P P PP PG P P P A P P +P P P P P +P
Sbjct: 975 IPPPPPL--PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1032
Query: 478 GYSEPAFG--PCFSMP-RGKPPAPSPRGQKASPPTLAPATA--SPPTTAGSNNPCLTQLL 532
P G P +P G PP P G PP P PP G+ P L
Sbjct: 1033 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1092
Query: 533 TAAKPEQALEPPLVSSTLLRSPGSPQETV---PEFPCTFLPPTPAPTP----PRPPPGPA 585
A P PPL + P P + P P +PP P P P P PPP P
Sbjct: 1093 GAGIPP---PPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPP-PPPLPGAGIPPPPPLPR 1148
Query: 586 TLAPSRPLLVPKAERLSPPAPSGS---ERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRP 642
P P L PP P L G + P P V + PP P+ G P
Sbjct: 1149 VGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG-VGIPPPPPLPGVGIPPPPPLPGAGIP 1207
Score = 91.7 bits (226), Expect = 3e-18
Identities = 110/355 (30%), Positives = 124/355 (34%), Gaps = 70/355 (19%)
Query: 308 LPQPPMP-SNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPL 366
LP PP+P + P PP G P PP A L L P P
Sbjct: 932 LPLPPLPGAGIPPPPPLP---------GAAIPPPPPLPGAGIPLP--PPLPGAGIPPPPP 980
Query: 367 DSSAFLSSDFLLPE---DPKPRLP----PPPVPPPLLHYPPPAKVPGLEPCPPPPFP--- 416
A + LP P P LP PPP P P PPP +PG PPPP P
Sbjct: 981 LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1040
Query: 417 ----PMAPPTALLQEEPLFSPRFPFPTVPPAPGVS---PLPAPAAFPPTPQSVPS---PA 466
P P + PL P P PP PG P P P A P P +P P
Sbjct: 1041 IPPPPPLPGAGIPPPPPL--PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1098
Query: 467 PTPFPIELLPLGYSEPAFG--PCFSMP-RGKPPAPSPRGQKASPPTLAPATA--SPPTTA 521
P P P +P P G P +P G PP P G PP P PP
Sbjct: 1099 PPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLP 1158
Query: 522 GSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPE---FPCTFLPPTP----- 573
G+ P L A P PPL + P P +P P +PP P
Sbjct: 1159 GAGIPPPPPLPGAGIPPP---PPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGM 1215
Query: 574 ----APTPPRPPPG-----PATLAPSRPLLVPKAER-----------LSPPAPSG 608
AP PP PPPG P L S P L+P+ L PP PSG
Sbjct: 1216 GIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPPLPSG 1270
Score = 60.8 bits (146), Expect = 5e-09
Identities = 59/196 (30%), Positives = 68/196 (34%), Gaps = 46/196 (23%)
Query: 309 PQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDS 368
P PP+P PP P V G +PP P PL
Sbjct: 1131 PPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPP--------------------PPPLPG 1170
Query: 369 SAFLSSDFLLPEDPKPRLP----PPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTAL 424
+ P P LP PPP P P + PPP +PG PPPP P M P A
Sbjct: 1171 AGI---------PPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPA- 1220
Query: 425 LQEEPLFSPRFPFPTVPPAPGVSPLP-APAAFPP-TPQSVPSPAPTPFPIELLPLGYSEP 482
P P P PP G+ P P P + PP PQ S PTP LP
Sbjct: 1221 --------PAPPLP--PPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPPLPSG 1270
Query: 483 AFGPCFSMPRGKPPAP 498
FG + +G P
Sbjct: 1271 LFGLGMNQDKGSRKQP 1286
Score = 55.5 bits (132), Expect = 2e-07
Identities = 72/263 (27%), Positives = 87/263 (33%), Gaps = 33/263 (12%)
Query: 395 LLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLF-SPR---FPFPTVPPAPGVS-PL 449
+L PP +PG PCPP P T E L SPR + P +S P
Sbjct: 754 VLTLPPVDGLPGRPPCPPG--AESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPP 811
Query: 450 PAPAAFPPTPQSVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKP-PAPSPRGQKASP- 507
P P+ Q P P P I E + F P P P P + +S
Sbjct: 812 PPPSLLWSAGQGQPGSQP-PHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSM 870
Query: 508 PTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPG--------SPQE 559
P L PP G P L + A P+ PPL + +L P P
Sbjct: 871 PGLGMVPPPPPPLPGMTVPTLP---STAIPQ---PPPLQGTEMLPPPPPPLPGAGIPPPP 924
Query: 560 TVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAERLSPPAPSGSERRLSGDLSS 619
+P LPP P P PPP P P P L L PP P
Sbjct: 925 PLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGA---------GI 975
Query: 620 MPGPGTLSVRVSPPQPILSRGRP 642
P P + PP P+ G P
Sbjct: 976 PPPPPLPGAGIPPPPPLPGAGIP 998
>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
Length = 3230
Score = 95.5 bits (236), Expect = 2e-19
Identities = 117/399 (29%), Positives = 155/399 (38%), Gaps = 35/399 (8%)
Query: 226 VPVLLGDPEEEPGGRQLLDLNCFLSDISDTLFTMTQSGPSPLQLPPEDAYVGNADMIQPD 285
VP L P P + + + S +S T+ ++ S P+ +P +A + P
Sbjct: 1403 VPSSLPGPASSP--MPIPNSSPLASPVSSTV-SVPLSSSLPISVPTTLPAPASAPLTIPI 1459
Query: 286 LTPLQPSLDDFMDISDFFTNSRLPQPPMPSNFPEPPSFSPVVDSLFSSG-TLGPEVPPAS 344
PL S T+ P P+ P PPS +P S +S TLG P+
Sbjct: 1460 SAPLTVSASG----PALLTSVTPPLAPVVPAAPGPPSLAPSGASPSASALTLGLATAPSL 1515
Query: 345 SAMTHLSGHSRLQARNSC--PGPLDSSAFLSSDFLLPED----PKPRLPPPPVPPPLLHY 398
S+ + GH L A S PG + A S L+P P P P P L
Sbjct: 1516 SS-SQTPGHPLLLAPTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLA 1574
Query: 399 PPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPT 458
P + L P P AP TA+L P P P P + P+PG +P+ A + P
Sbjct: 1575 PASSASQALAT---PLAPMAAPQTAILAPSPA-PPLAPLPVLAPSPGAAPVLASSQ-TPV 1629
Query: 459 PQSVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPP 518
P PS P P+ P P + P PSP AS TLA A A P
Sbjct: 1630 PVMAPSSTPGTSLASASPVPAPTPVLAPSSTQTMLPAPVPSPLPSPASTQTLALAPALAP 1689
Query: 519 TTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGS-----PQETVPEFPCTFLPPTP 573
T GS +P T L P + P + TL +P S P +T+ P L PT
Sbjct: 1690 TLGGS-SPSQTLSLGTGNP----QGPFPTQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQ 1744
Query: 574 ----APTPPRPPPGPATLAPSRPL-LVPKAERLSPPAPS 607
AP PP P P AP+ L L P + S AP+
Sbjct: 1745 TLSLAPAPPLAPASPVGPAPAHTLTLAPASSSASLLAPA 1783
Score = 66.6 bits (161), Expect = 9e-11
Identities = 107/397 (26%), Positives = 141/397 (35%), Gaps = 59/397 (14%)
Query: 282 IQPDLTPLQPSLDDFMDISDFFTNSRLPQPPMPSN---FPEPPSFSPVVDSLFSSGTLGP 338
+ P P L ++ T RLP P + + P P P++ + S P
Sbjct: 1327 LAPAPRPPSSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLVRPLLKLVHSPS---P 1383
Query: 339 EVPPASSAMTHLSGHSRLQARNSCPGPLDSSAFL--SSDFLLPEDPKPRLP-----PPPV 391
EV ++ L+ S L +S PGP S + SS P +P P V
Sbjct: 1384 EVSASAPGAAPLTISSPLHVPSSLPGPASSPMPIPNSSPLASPVSSTVSVPLSSSLPISV 1443
Query: 392 PPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPP-------AP 444
P L P PA P P P + P L P +P P PP +P
Sbjct: 1444 PTTL---PAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPAAPGPPSLAPSGASP 1500
Query: 445 GVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKP---PAPSPR 501
S L A P+ S +P P+ L P P + P P PA +
Sbjct: 1501 SASALTLGLATAPSLSSSQTPG---HPLLLAPTSSHVPGLNSTVA-PACSPVLVPASALA 1556
Query: 502 GQKASPPTLAPATASPPTTAGSNNPCL-TQLLTAAKPEQAL-----EPPLVSSTLLR-SP 554
S P APA AS A S + L T L A P+ A+ PPL +L SP
Sbjct: 1557 SPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSPAPPLAPLPVLAPSP 1616
Query: 555 G------SPQETVPEFPCTFLP--------PTPAPTPPRPPPGPATLAPS---RPLLVPK 597
G S Q VP + P P PAPTP P T+ P+ PL P
Sbjct: 1617 GAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQTMLPAPVPSPLPSPA 1676
Query: 598 AERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQ 634
+ + AP+ L+ L TLS+ PQ
Sbjct: 1677 STQTLALAPA-----LAPTLGGSSPSQTLSLGTGNPQ 1708
Score = 63.9 bits (154), Expect = 6e-10
Identities = 85/299 (28%), Positives = 111/299 (37%), Gaps = 43/299 (14%)
Query: 309 PQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDS 368
P P+P P P + +PV L SS T P + P+S+ T L+ S + P P
Sbjct: 1605 PLAPLPVLAPSPGA-APV---LASSQTPVPVMAPSSTPGTSLASASPV------PAPTPV 1654
Query: 369 SAFLSSDFLLPEDPKPRLPPP---------PVPPPLLHYPPPAKVPGLEPCPPP-PFPP- 417
A S+ +LP LP P P P L P++ L P PFP
Sbjct: 1655 LAPSSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQ 1714
Query: 418 ---MAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIEL 474
+ P ++L+ P P + P +S PAP P +P P+PA T + L
Sbjct: 1715 TLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLSLAPAPPLAPASPVG-PAPAHT---LTL 1770
Query: 475 LPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTA 534
P S P PAP P A+ TLA A AS + A + + A
Sbjct: 1771 APASSSASLLAPASVQTLTLSPAPVPTLGPAAAQTLALAPASTQSPASQASSLVVSASGA 1830
Query: 535 AK---------PEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGP 584
A P EP + TL P SP T F P P PP PP P
Sbjct: 1831 APLPVTMVSRLPVSKDEPDTL--TLRSGPPSPPSTATSFG----GPRPRRQPPPPPRSP 1883
Score = 60.8 bits (146), Expect = 5e-09
Identities = 94/353 (26%), Positives = 132/353 (37%), Gaps = 78/353 (22%)
Query: 356 LQARNSCPGPLDSSAFLSSDFLLPEDPKPRLPP---PPVPPPLLHYPPPAKV-------P 405
+QA PGP S SS P P VPP +++ K+
Sbjct: 1260 IQAVAPTPGPTPVSVLPSSTPSTTPAPTGLSLPLAANQVPPTMVNNTGVVKIVVRQAPRD 1319
Query: 406 GLEPCPP---PPFPPMAPPTALLQEEPLFSP-RFPFPTVPPAPGVSPLPAPAAFPPTPQS 461
GL P PP P PP + A+L P +P R P PT+ A +P+P P P +
Sbjct: 1320 GLTPVPPLAPAPRPPSSGLPAVLNPRPTLTPGRLPTPTLGTAR--APMPTPTLVRPLLKL 1377
Query: 462 VPSPAP--TPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATAS--- 516
V SP+P + PL S P P S+P PA SP S P +P +++
Sbjct: 1378 VHSPSPEVSASAPGAAPLTISSPLHVPS-SLPG---PASSPMPIPNSSPLASPVSSTVSV 1433
Query: 517 ----------PPTTAGSNNPCLTQLLTAAKPEQALEPPLVSS-------TLLRSPGSPQ- 558
P T + LT ++A A P L++S + +PG P
Sbjct: 1434 PLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPAAPGPPSL 1493
Query: 559 ----------------ETVPEFPCTFLPPTP---APTPPRPPPGPATLAPS-RPLLVPKA 598
T P + P P APT P +T+AP+ P+LVP +
Sbjct: 1494 APSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAPACSPVLVPAS 1553
Query: 599 ERLSP------PAP---------SGSERRLSGDLSSMPGPGTLSVRVSPPQPI 636
SP PAP S + + L+ L+ M P T + SP P+
Sbjct: 1554 ALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSPAPPL 1606
Score = 55.8 bits (133), Expect = 2e-07
Identities = 85/316 (26%), Positives = 113/316 (35%), Gaps = 59/316 (18%)
Query: 382 PKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVP 441
P P L P P P+ P + + P PP P PP +L PL P V
Sbjct: 1028 PGPELSAQPTPGPVPQVLPASLMVSASPAGPPLIPASRPPGPVLL-PPLQPNSGSLPQVL 1086
Query: 442 PAP-----GVSPLPAPA-AFPPTPQSVP--SPAPTPFPIELL-----PLGYSEP------ 482
P+P G S P P + PTP + SPAP P LL P GY+ P
Sbjct: 1087 PSPLGVLSGTSRPPTPTLSLKPTPPAPVRLSPAPPPGSSSLLKPLTVPPGYTFPPAAATT 1146
Query: 483 -----AFGPCFSMPRGKPPAPS------------PRGQKASPPTLAPATASPPTTAGSNN 525
A ++P PAP P G+ S LA P AG +
Sbjct: 1147 TSTTTATATTTAVP-APTPAPQRLILSPDMQARLPSGEVVSIGQLASLAQRPVANAGGSK 1205
Query: 526 PCLTQL------LTAAKPEQAL--EP-PLVSSTL-LRSPGSPQETVPEFPCTFL----PP 571
P Q+ LT A+ Q +P PL + + L S G + + L P
Sbjct: 1206 PLTFQIQGNKLTLTGAQVRQLAVGQPRPLQRNVVHLVSAGGQHHLISQPAHVALIQAVAP 1265
Query: 572 TPAPTPPR--PPPGPATLAPSRPLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTLSVR 629
TP PTP P P+T L +P A PP + + + P G
Sbjct: 1266 TPGPTPVSVLPSSTPSTTPAPTGLSLPLAANQVPPTMVNNTGVVKIVVRQAPRDG----- 1320
Query: 630 VSPPQPILSRGRPDSN 645
++P P+ RP S+
Sbjct: 1321 LTPVPPLAPAPRPPSS 1336
Score = 54.3 bits (129), Expect = 5e-07
Identities = 95/370 (25%), Positives = 128/370 (34%), Gaps = 88/370 (23%)
Query: 384 PRLPPPPVPPPLLHYPPPAKVPGLEPCP-PPPFPPMAP-PTALLQEEPLFSPRFPFPTVP 441
PR P P P P PA +P L P P P P AP P +L P P+ P
Sbjct: 2437 PRPAPRPRPTPA---SAPAAIPALVPVPVSAPVPISAPNPITIL-------PVHILPSPP 2486
Query: 442 PAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPR 501
P + P +PA PP P P PA TP P + + S P S+P P
Sbjct: 2487 PPSQIPPCSSPACTPP-PACTPPPAHTPPPAQTCLVTPSSPLLLGPPSVPISASVTNLPL 2545
Query: 502 GQKASPPTLAPATASP-----PTTAGSNN------------PCLTQLLTAAKPEQALEPP 544
G + A A ASP + A S P ++L ++ +L P
Sbjct: 2546 GLRPEAELCAQALASPESLELASVASSETSSLSLVPPKDLLPVAVEILPVSEKNLSLTPS 2605
Query: 545 LVSSTL----------LRSPGSPQET--------------VPEFPCTFLPPTPAPTPPRP 580
S TL +P S + T V E LPP+ A P
Sbjct: 2606 APSLTLEAGSIPNGQEQEAPDSAEGTTLTVLPEGEELPLCVSESNGLELPPSAASDEPLQ 2665
Query: 581 PPGPA-------------TLAPSRPLLVPKAERLSP------------PAPSGSERRLSG 615
P A T +P +P + AE +P P+P+ RR +
Sbjct: 2666 EPLEADRTSEELTEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSPEGPSPARPPRRRTS 2725
Query: 616 DLSSMPGPGTLSVRVSPPQPILSRGRPDSNKTENRRITHISAEQ--KRRFNIKLGFDTLH 673
+ G GT PP P + R K R +T + ++ +RR + TL
Sbjct: 2726 ADVEIRGQGT-GRPGQPPGPKVLR------KLPGRLVTVVEEKELVRRRRQQRGAASTLV 2778
Query: 674 GLVSTLSAQP 683
VS SA P
Sbjct: 2779 PGVSETSASP 2788
Score = 52.0 bits (123), Expect = 2e-06
Identities = 57/217 (26%), Positives = 77/217 (35%), Gaps = 37/217 (17%)
Query: 409 PCPPP-PFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAP 467
P PPP P P +LQ P R P + P+P PP P+ P P
Sbjct: 981 PDPPPRPKPVKMKVNRMLQPVPKQEGRTVVVVNNPRAPLGPVPVRP--PPGPELSAQPTP 1038
Query: 468 TPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPC 527
P P ++LP A SP G P L PA+ P
Sbjct: 1039 GPVP-QVLPASLMVSA---------------SPAG-----PPLIPASRPPGPV------- 1070
Query: 528 LTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATL 587
LL +P P ++ S L G+ + P PP P P PPPG ++L
Sbjct: 1071 ---LLPPLQPNSGSLPQVLPSPLGVLSGTSRPPTPTLSLKPTPPAPVRLSPAPPPGSSSL 1127
Query: 588 APSRPLLVPKAERLSP-PAPSGSERRLSGDLSSMPGP 623
+PL VP P A + S + +++P P
Sbjct: 1128 L--KPLTVPPGYTFPPAAATTTSTTTATATTTAVPAP 1162
Score = 51.6 bits (122), Expect = 3e-06
Identities = 106/411 (25%), Positives = 137/411 (33%), Gaps = 95/411 (23%)
Query: 307 RLPQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPL 366
R+P+P P P P S + +L P A + +T L H P P
Sbjct: 2435 RVPRPA-PRPRPTPASAPAAIPALVPVPVSAPVPISAPNPITILPVHI-------LPSPP 2486
Query: 367 DSSAFLSSDFLLPEDPKPRLPPPPV-PPPLLHYPPPAKVPGLEPCPPPPF-PPMAPPTAL 424
S +P P PPP PP H PPPA+ + P P PP P +A
Sbjct: 2487 PPSQ-------IPPCSSPACTPPPACTPPPAHTPPPAQTCLVTPSSPLLLGPPSVPISAS 2539
Query: 425 LQEEPL-FSPRFPFPTVPPAPGVSPLPAPAAFPPTPQS--VPSPAPTPFPIELLPLGYSE 481
+ PL P A S A A T VP P +E+LP+
Sbjct: 2540 VTNLPLGLRPEAELCAQALASPESLELASVASSETSSLSLVPPKDLLPVAVEILPVSEKN 2599
Query: 482 PAFGPCFSMPRGKPPAPS-PRGQKASPPTLAPATASPPTTAGSNNP-CLTQ-----LLTA 534
+ P S P A S P GQ+ P A T G P C+++ L +
Sbjct: 2600 LSLTP--SAPSLTLEAGSIPNGQEQEAPDSAEGTTLTVLPEGEELPLCVSESNGLELPPS 2657
Query: 535 AKPEQALEPPLVSS----------TLLRSPGSPQETVPE---FPCTFLPPTPAPTPPRP- 580
A ++ L+ PL + T SP PQE V P T T +P P P
Sbjct: 2658 AASDEPLQEPLEADRTSEELTEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSPEGPSPA 2717
Query: 581 -----------------------PPGPATLA--PSRPL---------------------L 594
PPGP L P R + L
Sbjct: 2718 RPPRRRTSADVEIRGQGTGRPGQPPGPKVLRKLPGRLVTVVEEKELVRRRRQQRGAASTL 2777
Query: 595 VPKAERLSPPAPSGSERRLSGDLSSMP--GP----GTLSVRVSPPQPILSR 639
VP S S S R +SG SS P GP + S+ P QP ++R
Sbjct: 2778 VPGVSETSASPGSPSVRSMSGPESSPPIGGPCEAAPSSSLPTPPQQPFIAR 2828
Score = 50.4 bits (119), Expect = 7e-06
Identities = 67/268 (25%), Positives = 97/268 (36%), Gaps = 63/268 (23%)
Query: 384 PRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPPA 443
PR P PVP PPP +P P P P + P + ++ P P P
Sbjct: 1015 PRAPLGPVPVR----PPPGPELSAQPTPGP-VPQVLPASLMVSASPAGPPLIP------- 1062
Query: 444 PGVSPLPAPAAFPP-TPQSVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRG 502
S P P PP P S P P P+ +L +PP P+
Sbjct: 1063 --ASRPPGPVLLPPLQPNSGSLPQVLPSPLGVL--------------SGTSRPPTPT-LS 1105
Query: 503 QKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVP 562
K +PP AP SP GS++ L + LT P PP ++T + + T
Sbjct: 1106 LKPTPP--APVRLSPAPPPGSSS--LLKPLTV--PPGYTFPPAAATTTSTTTATATTTA- 1158
Query: 563 EFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAERLS----------PPAPSGSER- 611
PAPT P P L+P +P E +S P A +G +
Sbjct: 1159 ---------VPAPT---PAPQRLILSPDMQARLPSGEVVSIGQLASLAQRPVANAGGSKP 1206
Query: 612 ---RLSGDLSSMPGPGTLSVRVSPPQPI 636
++ G+ ++ G + V P+P+
Sbjct: 1207 LTFQIQGNKLTLTGAQVRQLAVGQPRPL 1234
Score = 40.4 bits (93), Expect = 0.007
Identities = 55/218 (25%), Positives = 75/218 (34%), Gaps = 61/218 (27%)
Query: 441 PPAPGVSPLPAPAAFPPT--------PQSVPSPAPTPF----PIELLPLGYSEPAFG--- 485
P +P V + P + PP S+P+P PF IEL G P G
Sbjct: 2788 PGSPSVRSMSGPESSPPIGGPCEAAPSSSLPTPPQQPFIARRHIELGVTGGGSPENGDGA 2847
Query: 486 ------PCFSMPRGKPP----APSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAA 535
P RG+PP +P+ G+ AP++ T G++ + L A
Sbjct: 2848 LLAITPPAVKRRRGRPPKKNRSPADAGRGVDE---APSSTLKGKTNGADPVPGPETLIVA 2904
Query: 536 KPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLV 595
P LEP L+ P P P P+P P PLL
Sbjct: 2905 DP--VLEPQLI------------------------PGPQPLGPQPVHRP------NPLLS 2932
Query: 596 PKAERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPP 633
P +R P + + G +SS G G R PP
Sbjct: 2933 PVEKRRRGRPPKARDLPIPGTISS-AGDGNSESRTQPP 2969
Score = 30.0 bits (66), Expect = 9.2
Identities = 36/119 (30%), Positives = 43/119 (36%), Gaps = 15/119 (12%)
Query: 403 KVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPL-PAPAAFPPTPQS 461
K G +P P P +A P Q P P P P P P +SP+ PP +
Sbjct: 2888 KTNGADPVPGPETLIVADPVLEPQLIPGPQPLGPQPVHRPNPLLSPVEKRRRGRPPKARD 2947
Query: 462 VPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTT 520
+P P I G SE P PP PSP PP L TA+ T
Sbjct: 2948 LPIPG----TISSAGDGNSESRTQP--------PPHPSP--LTPLPPLLVCPTATVANT 2992
>gi|47132519 Ras association and pleckstrin homology domains 1
isoform 1 [Homo sapiens]
Length = 1250
Score = 94.7 bits (234), Expect = 3e-19
Identities = 122/417 (29%), Positives = 151/417 (36%), Gaps = 82/417 (19%)
Query: 272 EDAYVGNADMIQPDLTPLQPSLDDFMDISDFFTNSR----LPQPPMPSNFPEPPSFSPVV 327
E++ + + T L P L I +T S+ LP PP P P PP P
Sbjct: 588 EESSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPP 647
Query: 328 ----DSLFSSGTLGPEVPPASSA--MTHLSGHSRLQARNSCPGPLDSSAFLSSDFLLPED 381
S S+G+ P S+ + + S HS + P + S + + P
Sbjct: 648 PLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNG 707
Query: 382 PKPRLPPPPVPP---------------PLLHY----PPPAKV----------PGLEPCPP 412
P PPPP PP P L PPP K+ P P PP
Sbjct: 708 VVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPP 767
Query: 413 P---PFPPMAPPTALLQEEPLFSPRFPFPTV------PPAPGVSPLPAPAAFPPT--PQS 461
P P PP APP L+ S + P V P P V P AFP + P S
Sbjct: 768 PIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPS 827
Query: 462 VPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKAS---PPTLAPATASPP 518
P+P P P P LP S A P P P PS Q AS PP PA S P
Sbjct: 828 PPTP-PVPVPPPTLPKQQSFCAKPP----PSPLSPVPSVVKQIASQFPPPPTPPAMESQP 882
Query: 519 TTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPP 578
N Q A K + +P SS + SP P PE F PP P+P P
Sbjct: 883 LKPVPAN-VAPQSPPAVKAKPKWQP---SSIPVPSPDFPPPP-PESSLVFPPPPPSPVPA 937
Query: 579 RPPPGPATLAPSRPLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQP 635
PPP P T +P+ P SGS + + SS G + PP P
Sbjct: 938 PPPPPPPTASPT-------------PDKSGSPGKKTSKTSSPGG------KKPPPTP 975
Score = 84.7 bits (208), Expect = 3e-16
Identities = 81/293 (27%), Positives = 105/293 (35%), Gaps = 52/293 (17%)
Query: 382 PKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTA--------------LLQE 427
P P LPPPP PPP PPP P PPPP P + P+A LQ
Sbjct: 624 PSPPLPPPPPPPP----PPPPPPPP----PPPPLPSQSAPSAGSAAPMFVKYSTITRLQN 675
Query: 428 EPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYSEPAFGPC 487
S P PP + PP P P P P P + +PA PC
Sbjct: 676 ASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPA--PC 733
Query: 488 F-SMPRGKPPAP-------------SPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLT 533
S+P+ P P +P PP AP P P T T
Sbjct: 734 APSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKT 793
Query: 534 AAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPL 593
A PP + P P + P FP +++PP+P PTPP P P P P +
Sbjct: 794 VAPVVTQAAPPTPT-----PPVPPAKKQPAFPASYIPPSP-PTPPVPVPPPT--LPKQQS 845
Query: 594 LVPKAERLSPPAPSGSERRLSGDLSSM--PGPGTLSVRVSPPQPILSRGRPDS 644
K PP+P + ++S P P ++ P +P+ + P S
Sbjct: 846 FCAK----PPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQS 894
Score = 61.2 bits (147), Expect = 4e-09
Identities = 89/336 (26%), Positives = 116/336 (34%), Gaps = 82/336 (24%)
Query: 266 PLQLPPEDAYVGNADMIQPDLTPLQPSLDDFMDISDFFTNSRLPQPPMPSNFPEPPSFSP 325
P+ +PP + +P +PL P I+ S+ P PP P P P
Sbjct: 832 PVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIA-----SQFPPPPTPPAMESQP-LKP 885
Query: 326 VVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDSSAFLSSDFLLPEDPKPR 385
V + P+ PPA A S +P P P
Sbjct: 886 V------PANVAPQSPPAVKAKPKWQPSS-----------------------IPV-PSPD 915
Query: 386 LPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPG 445
PPPP L+ PPP P P PPPP PPTA + SP G
Sbjct: 916 FPPPPPESSLVFPPPP---PSPVPAPPPP----PPPTASPTPDKSGSPGKKTSKTSSPGG 968
Query: 446 VSPLPAPAAFPPTPQ---SVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRG 502
P PPTPQ S+ S + P P S + + PPA S
Sbjct: 969 KKP-------PPTPQRNSSIKSSSGAEHPEPKRPSVDS--------LVSKFTPPAESGSP 1013
Query: 503 QKAS-PPTLAPATASPPTTAGSNNP-CLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQET 560
K + PP AP +G N P L Q +AK P++S G +++
Sbjct: 1014 SKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAK------APVLS-------GRGKDS 1060
Query: 561 VPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVP 596
V EF P+P PPP P T P P+ +P
Sbjct: 1061 VVEF------PSPPSDSDFPPPPPETELPLPPIEIP 1090
Score = 35.8 bits (81), Expect = 0.17
Identities = 63/253 (24%), Positives = 78/253 (30%), Gaps = 58/253 (22%)
Query: 309 PQPPMPSNFPEPPSFSPVVDSLF-SSGTLGPEVPPASSAMTHLSGHSR----LQARNSCP 363
P+P PS F+P +S S TL P P +LSG + Q S
Sbjct: 990 PEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAK 1049
Query: 364 GPLDSSAFLSSDFLLPEDPKPRLPPPPVPPPLLHYPP---PAKVPG-------------- 406
P+ S S P P PPP P L PP PA G
Sbjct: 1050 APVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQ 1109
Query: 407 ------LEPCPPPPFPPMAPPTALLQEEPLFSPRFP--FPTVPPAPGVSPLPAPAAFPPT 458
++ PPP P T L Q E P P VP +P S P
Sbjct: 1110 QWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTSPKSSLSVQPGFLADL 1169
Query: 459 PQSVPSPAPT------------------------PFPIELLP----LGYSEPAFGPCFSM 490
+++ + T P P ELL GY ++
Sbjct: 1170 NRTLQRKSITRHGSLSSRMSRAEPTATMDDMALPPPPPELLSDQQKAGYGGSHISGYATL 1229
Query: 491 PRGKPPAPSPRGQ 503
RG PPAP R Q
Sbjct: 1230 RRGPPPAPPKRDQ 1242
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 92.0 bits (227), Expect = 2e-18
Identities = 116/472 (24%), Positives = 161/472 (34%), Gaps = 83/472 (17%)
Query: 233 PEEEPGGRQLLDLNCFLSDISDTLFTMTQSGPSPLQLPPE-------DAYVGNADMIQPD 285
P E+ G L+ ++D+ + S + PP D +GN +
Sbjct: 771 PTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGN---LSSP 827
Query: 286 LTPLQPSLD-----DFMDISDFFTNSRLPQPPMPSNFPEPPSFSP--------------- 325
++P++ S F D + P PP P P P + +P
Sbjct: 828 VSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPT 887
Query: 326 --VVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDSSAFLSSDFLLPE--D 381
VV+ F P + A++ S + P + +S P
Sbjct: 888 PSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATP 947
Query: 382 PKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAP-PTALLQEEPLFSPRFPFPT- 439
P P+ P P PP A P + P P P AP P A P P P P
Sbjct: 948 PSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKG 1007
Query: 440 --VPPA---------PGVSPLPA-----PAAFPPTPQSVPSPAPTPFPIELLPLG-YSEP 482
PPA P +P P PAA PP+P+ P+ P P P P
Sbjct: 1008 APTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSP 1067
Query: 483 AFGPCFSM--------------PRGKPPAPSPRGQK----ASPPTLAPATASPPTTAGSN 524
GP P+G P PSP+G A+PP+ A+PP
Sbjct: 1068 KGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPT 1127
Query: 525 NPCLTQLLTAAKPEQALEPPL-VSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPG 583
P T + K A PP +T +P SP+ + P P TPA TPP P G
Sbjct: 1128 TPAATP--PSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGG 1185
Query: 584 PATLAPSRPLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQP 635
AT +P P A +PP+P G G + P + +PP P
Sbjct: 1186 LATPSPKGAPTTPAA---TPPSPKG------GLATPSPKGAPTTPAATPPSP 1228
Score = 87.8 bits (216), Expect = 4e-17
Identities = 103/341 (30%), Positives = 134/341 (39%), Gaps = 72/341 (21%)
Query: 334 GTLGPEVPPA--SSAMTHLSGHSRLQARNSCPGPLDSSAFLSSDFLLPEDPKPRLPPPP- 390
G+ GP+ P SS ++ + + S G DS A S P P P+ P P
Sbjct: 813 GSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHS----PTPPSPKGAPTPS 868
Query: 391 -----------VPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPT 439
+PP P +P + P P P AP ++ P + P P
Sbjct: 869 AVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPK 928
Query: 440 ---VPPAPGVSPLPAPAAFPPTPQ---SVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRG 493
P+P +P P PAA PP+P+ + PSP P P P P GP P+G
Sbjct: 929 GIPASPSPKGAPTP-PAATPPSPKGGPATPSPKWAPTPPAATP---PSPKGGPATPSPKG 984
Query: 494 KP--PA---PSPRGQKASP-----PTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEP 543
P PA PSP+G A+P PT P +PP+ GS P T A A P
Sbjct: 985 APTPPAATPPSPKGGPATPSPKGAPT--PPAVTPPSPKGS--PAATPFPKGASTPPAATP 1040
Query: 544 PLVSSTLLRSP-GSPQET-VPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAERL 601
P SP GSP T +P+ P TPA T P P GPAT + P A
Sbjct: 1041 P--------SPKGSPAATPLPKGA----PTTPAATLPSPKGGPATPSLKGAPTPPAA--- 1085
Query: 602 SPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRP 642
+PP+P G GP T S + +P P + P
Sbjct: 1086 TPPSPKG-------------GPATPSPKGAPMPPAATPPSP 1113
Score = 82.0 bits (201), Expect = 2e-15
Identities = 97/370 (26%), Positives = 138/370 (37%), Gaps = 56/370 (15%)
Query: 309 PQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDS 368
P P P P PP+ +P S + TL P P+S G + ++ P +
Sbjct: 1324 PGTPPPKGAPTPPAVTP--PSPKGTPTL-PATTPSSKG-----GPTTPSSKEGPTPPAAT 1375
Query: 369 SAFLSSDFLLPEDPK--PRLPPP---PVPPPLLHYPP---PAKVPGLEPCPPPPFPPMAP 420
+ + P PK P +P P P P ++ P PA E P + P
Sbjct: 1376 PSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTP 1435
Query: 421 PTAL---LQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSP-------APTPF 470
P L++ P S P P + G LPA PP+P+ P+P +P
Sbjct: 1436 PAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVT--PPSPKEPPAPKQVATSSSPKKA 1493
Query: 471 PIELLPLGYSE-PAFGPCFSMPRGKPPAPSPRGQ----------KASPPTLAPATASPPT 519
P P+G PA P S P+ P PS R K +P TLAP A P
Sbjct: 1494 PATPAPMGAPTLPAVIP--SSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPP 1551
Query: 520 TAGSNNPCLTQLLTAAKP-------EQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPT 572
+P T + K ++A PP V+ + + SP+E + T P
Sbjct: 1552 AMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPK 1611
Query: 573 PAPTPPRPPPGPATLAPSRPLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSP 632
APTPP P P+ P PK SPP S + S P +++ ++
Sbjct: 1612 EAPTPPAVTPPSPEKGPATP--APKGTPTSPPVTPSSLK------DSPTSPASVTCKMGA 1663
Query: 633 PQPILSRGRP 642
P S+G P
Sbjct: 1664 TVPQASKGLP 1673
Score = 81.3 bits (199), Expect = 3e-15
Identities = 86/337 (25%), Positives = 116/337 (34%), Gaps = 68/337 (20%)
Query: 309 PQPPMPSNFPEPPSFSPVVDS--LFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPL 366
P P P P PP+ +P L + G PA++ + G + + + P
Sbjct: 1094 PATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPA 1153
Query: 367 DSSAFLSSDFLLPEDPKPRL--PPPPVPPPLLHYPPPAKVPGLEPCPP------PPFPPM 418
+ P PK L PPP P PP+ GL P P P
Sbjct: 1154 AT----------PPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPP 1203
Query: 419 APPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLG 478
+P L P +P P T P G P+P P TP + P
Sbjct: 1204 SPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATP--------------- 1248
Query: 479 YSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPE 538
P GP P+G P P+ A+PP+L A+PP G+ NP +
Sbjct: 1249 -PSPKGGPATPPPKGAPTPPA-----ATPPSLKGGLATPP-HKGAPNPAVV--------- 1292
Query: 539 QALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKA 598
+P SP+ P P PA TPP P P T P P
Sbjct: 1293 --------------TPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKG---APTP 1335
Query: 599 ERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQP 635
++PP+P G+ + SS GP T S + P P
Sbjct: 1336 PAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPP 1372
Score = 79.0 bits (193), Expect = 2e-14
Identities = 108/411 (26%), Positives = 144/411 (35%), Gaps = 75/411 (18%)
Query: 288 PLQPSLDDFMDISDFFTNSRLP------QPPMPSNFPEP-------PSFSPVVDSLFSSG 334
PL P+ + ++ N+ P P +P + P P P + VD + +
Sbjct: 699 PLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTS 758
Query: 335 TLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDSSAFLSSDFLLPEDPKPRLPPP----- 389
L P T SG S A S G L A S + P+ + PP
Sbjct: 759 ALAPVASSPKECPTEDSGAS---ATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSA 815
Query: 390 -----------PVPPPLLHYPPPAKV--------PGLEPCPPPPFPPMAP-PTALLQEEP 429
PV P + P + P P PP P AP P+A+ P
Sbjct: 816 GPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSP 875
Query: 430 LFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYSEPAFGPCFS 489
P T P P V LP P P TP +PA L + S P
Sbjct: 876 KGVTLPPKET--PTPSVVNLPFPKEGPATPAPKQAPA--------LSMTSSSPKKARATP 925
Query: 490 MPRGKPPAPSPRGQKASP------PTLAPATASP---PTTAGSNNPCLTQLLTAAKPEQA 540
P+G P +PSP+G P P PAT SP PT + P P+ A
Sbjct: 926 APKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGA 985
Query: 541 LEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATL-----APSRPLLV 595
PP ++T G P P+ P PA TPP P PA A + P
Sbjct: 986 PTPP--AATPPSPKGGPATPSPKGA----PTPPAVTPPSPKGSPAATPFPKGASTPPAAT 1039
Query: 596 PKAERLSP---PAPSGSERRLSGDL-SSMPGPGTLSVRVSPPQPILSRGRP 642
P + + SP P P G+ + L S GP T S++ +P P + P
Sbjct: 1040 PPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSP 1090
Score = 78.6 bits (192), Expect = 2e-14
Identities = 91/356 (25%), Positives = 129/356 (36%), Gaps = 34/356 (9%)
Query: 312 PMPSNFPEPPSFSPVVDS--LFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDSS 369
P P P P+ +P L + G PA++ + G + + + P +
Sbjct: 1212 PSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATP 1271
Query: 370 AFLSSDFLLPED---PKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQ 426
L P P P + PP P PP P P PP P +P T
Sbjct: 1272 PSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAP-TPPAATPPSPKGSPGTP--- 1327
Query: 427 EEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYSEPAFGP 486
P +P P T P G LPA + PS P P P PA P
Sbjct: 1328 -PPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTP 1386
Query: 487 CFSMPRGKPPAPSPRGQKASP------PTLAPATASPPTTAGSNNPCLTQLLTAAKPEQA 540
P+ P PSP+G SP P APAT P T G+ P L A +
Sbjct: 1387 --PSPKRGPAIPSPKGDPTSPAVIPLSPKKAPAT--PVTREGAATPSKGDLTPPAVTPVS 1442
Query: 541 LEPPLVSSTLLRSPGSPQE----TVPEF--PCTFLPPTP-----APTPPRPPPGPATL-A 588
L+ +S P +P T+P P PP P + +P + P PA + A
Sbjct: 1443 LKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGA 1502
Query: 589 PSRPLLVPKAERLSPPAPSGSERRL--SGDLSSMPGPGTLSVRVSPPQPILSRGRP 642
P+ P ++P + + P PS + + L S P TL+ + + P ++ P
Sbjct: 1503 PTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSP 1558
Score = 68.9 bits (167), Expect = 2e-11
Identities = 103/437 (23%), Positives = 148/437 (33%), Gaps = 66/437 (15%)
Query: 264 PSPLQLPPEDAYVGNADMIQPDLTPLQPSLDDFMDISDFFTNSRLPQPPMPSNFPEPPSF 323
PSP + PP V + P P P+ + +S P PS+ +P +
Sbjct: 1473 PSPKE-PPAPKQVATSS--SPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAP 1529
Query: 324 SPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDSSAFLSSDFLLPEDPK 383
+ + S + TL P+ AMT S + + P P ++ A SS K
Sbjct: 1530 TATLLSKKTPATLAPKEALIPPAMTVPSP----KKTPAIPTPKEAPATPSS--------K 1577
Query: 384 PRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAP-PTALLQEEPLFSPRFPFPT-VP 441
PP V P P K + P P P AP P A+ P P P P P
Sbjct: 1578 EASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTP 1637
Query: 442 PAPGVSP---------------------------LPAPAAFPPTPQSVPSPAPTPFPIEL 474
+P V+P LPA + + +PAP PI
Sbjct: 1638 TSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIIT 1697
Query: 475 LPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASP-----PTTAGSNNPCLT 529
P + P P + G K T+APA P TA + +
Sbjct: 1698 APTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHS 1757
Query: 530 QLLTAAKPEQALEPPLVSST---LLRSPGSPQETVPEFPCTFLPPTPAPTPPRPP----- 581
A PE PL ++ +L P S + P LP P+P P PP
Sbjct: 1758 PKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFL 1817
Query: 582 ---PGPATLAPSRPLLVPKAER---LSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPP-- 633
PG +PS+PL + L PP P L +MP P + + V P
Sbjct: 1818 PSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSA 1877
Query: 634 -QPILSRGRPDSNKTEN 649
QP+ + ++++
Sbjct: 1878 KQPVTKNNKGSGTESDS 1894
Score = 50.8 bits (120), Expect = 5e-06
Identities = 63/237 (26%), Positives = 85/237 (35%), Gaps = 43/237 (18%)
Query: 436 PFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKP 495
P PT+PP PAP P + + SP P+P I PL P ++P G
Sbjct: 41 PGPTLPPPCS----PAPQQCPLSAANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTA 96
Query: 496 P-----APSPRGQKASPPTLAPATAS-PPTTAGSNNPCLTQLLTAAKPEQALEPPLVSST 549
P P+ G SP LA A+ PT G+ + L A P +
Sbjct: 97 PEAPTFLPNLIGPPISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPN 156
Query: 550 LLRSPGS------------PQETVPEFPCTFLPPTPAPTPPRP--PPGPATLAPSRP--L 593
LL SP S P P T L P+ P P P P + + P
Sbjct: 157 LLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHC 216
Query: 594 LVPKAE---------------RLSPPAPSGSERRLSGDLSSMPGPGTLSVR--VSPP 633
+ P A L+ +P + +S L S PG+LS++ VSPP
Sbjct: 217 VTPMASIQSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPP 273
Score = 35.4 bits (80), Expect = 0.22
Identities = 46/198 (23%), Positives = 70/198 (35%), Gaps = 13/198 (6%)
Query: 405 PGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPS 464
P + P P +P ++ P T P PLP P P SV
Sbjct: 465 PPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLV 524
Query: 465 PAPTPFPIELLPLGYSEPAFGPC-FSMPRGKPPAPSPRGQKA--SPPTLAPATASP---- 517
PT ++ +P F P + K P P Q A + P+ ++SP
Sbjct: 525 KFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPL 584
Query: 518 PTTAGSNNPCLTQLLTAAKPEQALEPPL---VSSTLLR--SPGSPQETVPEFPCTFLPPT 572
A L + L KP ++ PL S+++++ S P P + + PT
Sbjct: 585 SPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPT 644
Query: 573 PAPTPPRPPPGPATLAPS 590
A P PA +AP+
Sbjct: 645 VAAF-PLESADPAGVAPT 661
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 91.3 bits (225), Expect = 3e-18
Identities = 114/395 (28%), Positives = 146/395 (36%), Gaps = 49/395 (12%)
Query: 258 TMTQSGPSPLQLPPEDAYVGNADM-IQPDLTPLQPSLDDFMDISDFFTNSRLPQPPMPSN 316
+M P PLQ E +G A + ++P L + L++ M + S L PP S
Sbjct: 403 SMQPKEPGPLQC--EAKPLGKAGVQLEPQL---EAPLNEEMPLLPPPEESPLSPPPEESP 457
Query: 317 FPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDSSAFLSSDF 376
PP S + PE PAS L L+ P P +S
Sbjct: 458 TSPPPEASRLSPP--------PEELPASPLPEALHLSRPLEESPLSPPPEES-------- 501
Query: 377 LLPEDPKPRLPP------PPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPL 430
P P P P P+ PP P PA L P PP P++PP +E PL
Sbjct: 502 --PLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSP--PPEASPLSPP---FEESPL 554
Query: 431 FSPRFPFPTVPP--APGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYSEPAFGPCF 488
P PT PP A +SP P + P P+ P +P P L P P P
Sbjct: 555 SPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPM-SPPPEASRLFPPFEESPLSPP-- 611
Query: 489 SMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEPPLVSS 548
P P +P P + SPP + PP + + P L+ L PP S
Sbjct: 612 --PEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEES 669
Query: 549 TLLRSP-GSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLL-VPKAERLSPPAP 606
L P SP PE PP +PT P P PA+ P L+ +P E P P
Sbjct: 670 PLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLP 729
Query: 607 SGSE---RRLSGDLSSMPGPGTLSVRVSPPQPILS 638
+ R LS P LS R P +P LS
Sbjct: 730 EEPQLCPRSEGPHLSPRPEEPHLSPR--PEEPHLS 762
Score = 86.3 bits (212), Expect = 1e-16
Identities = 129/480 (26%), Positives = 165/480 (34%), Gaps = 80/480 (16%)
Query: 191 RLRKPSREDDLLAPKQAEGRWPPPEQWCKQLFSSVVPVLLGDPEEEPGGRQLLDLNCFLS 250
RL P E + P + PPPE S + P P P L S
Sbjct: 571 RLSPPPEESPMSPPPEESPMSPPPEA------SRLFPPFEESPLSPPPEESPLSPPPEAS 624
Query: 251 DISDTLFTMTQSGP---SPLQLPPEDAYVGNADMIQ-----PDLTPLQPSLDDFMDISDF 302
+S S P SP+ PPE + + ++ P+ +PL P ++ S
Sbjct: 625 RLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEE-SPTSPP 683
Query: 303 FTNSRLPQPPMPSNFPEPPSFSPVV----DSLFSSGTLGPEVPPASSAMTHLSGHSRLQA 358
SRL PP S PP SP DSL S +P S + L +L
Sbjct: 684 PEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMS-------LPLEESPLLPLPEEPQLCP 736
Query: 359 RNSCPGPLDSSAFLSSDFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPM 418
R+ P L P +P L P P P H P A+ P L P P P
Sbjct: 737 RSEGP------------HLSPRPEEPHLSPRPEEP---HLSPQAEEPHLSPQPEEPCLCA 781
Query: 419 APPTALLQEEPLFSPRFPFPTVPPAPG---VSPLPAPAAFPPTPQSVPSPAPTPFPIELL 475
P EEP SP+ P + P P +SP P P+ P +P P L
Sbjct: 782 VP------EEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEE-PCLSPQPEESHLS 834
Query: 476 PLGYSEPAFGP----CFSMPRGKPPAPSPRGQKA-SPPTLAPATASPPTTAGSNNPCLTQ 530
P EP P P + P SPR +K P PA P P L+
Sbjct: 835 PQS-EEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSP 893
Query: 531 LLTAAKPEQALEPPL--VSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLA 588
LL + EPPL + L SP P+ +PP P P PP P A
Sbjct: 894 LLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQL----MPPDPLP----PPLSPIITA 945
Query: 589 PSRPLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDSNKTE 648
+ P L P E P G D S L +SPP P++N T+
Sbjct: 946 AAPPALSPLGELEYPFGAKG-----DSDPESPLAAPILETPISPP--------PEANCTD 992
Score = 84.0 bits (206), Expect = 5e-16
Identities = 100/345 (28%), Positives = 126/345 (36%), Gaps = 48/345 (13%)
Query: 311 PPMPSNFP--EPPSFSPVVDSLFSSG---TLGPEVPPASSAMTHLSGHSRLQARNSCPGP 365
PP P + P EP + G ++ P+ P G + +Q P
Sbjct: 374 PPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAP 433
Query: 366 LDSSAFLSSDFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTAL- 424
L+ L L P + P PPP P PP + L P PP P P AL
Sbjct: 434 LNEEMPL----LPPPEESPLSPPPEESPT----SPPPEASRLSP-PPEELPASPLPEALH 484
Query: 425 ----LQEEPLFSPRFPFPTVPPAPG--VSPLPAPAAFPPTPQSVPSPA---PTPFPIELL 475
L+E PL P P PP SPL PP +S PSPA P P E
Sbjct: 485 LSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPE-ESPPSPALETPLSPPPEAS 543
Query: 476 PLGYSEPAF--GPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLT 533
PL P F P P P +P P + SPP + PP + + P L
Sbjct: 544 PLS---PPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLF 600
Query: 534 AAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAP---- 589
E L PP S L P + + L P P +P PPP + ++P
Sbjct: 601 PPFEESPLSPPPEESPLSPPPEASR----------LSPPPEDSPMSPPPEESPMSPPPEV 650
Query: 590 SRPLLVPKAERLSPPAPSGSERRLSGDLSSMP-GPGTLSVRVSPP 633
SR +P RLSPP E LS P P + R+SPP
Sbjct: 651 SRLSPLPVVSRLSPPP---EESPLSPPPEESPTSPPPEASRLSPP 692
Score = 83.6 bits (205), Expect = 7e-16
Identities = 135/494 (27%), Positives = 179/494 (36%), Gaps = 79/494 (15%)
Query: 192 LRKPSREDDLLAPKQAEGRWPPPEQWCKQLFSSVVP--VLLGDP-EEEPGGRQLLDLNCF 248
L P E P +A PPPE +L +S +P + L P EE P +
Sbjct: 449 LSPPPEESPTSPPPEASRLSPPPE----ELPASPLPEALHLSRPLEESPLSPPPEESPLS 504
Query: 249 LSDISDTLFTMTQSGPSPLQLPPEDAYVGNADMIQPDLTPLQPSLDDFMDISDFFTNSRL 308
S + +S SP + P + P+ +PL P ++ +S
Sbjct: 505 PPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEE-SPLSPPPEELPT 563
Query: 309 PQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDS 368
PP S PP SP+ PP S M+ SRL P +
Sbjct: 564 SPPPEASRLSPPPEESPM------------SPPPEESPMSPPPEASRLFP------PFEE 605
Query: 369 SAFLSSDFLLPEDPKP---RLPPPPVPPPLLHYPPPAKVPGLEPCPPP------PFPPMA 419
S P P P RL PPP P+ PPP + P PPP P P ++
Sbjct: 606 SPLSPPPEESPLSPPPEASRLSPPPEDSPM--SPPPEESP---MSPPPEVSRLSPLPVVS 660
Query: 420 PPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTP-------FPI 472
+ +E PL P PT PP P P P +P SPA P P+
Sbjct: 661 RLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPL 720
Query: 473 E---LLPLGYSEPAF-----GPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSN 524
E LLPL EP GP S PR + P SPR ++ P L+P P +
Sbjct: 721 EESPLLPLP-EEPQLCPRSEGPHLS-PRPEEPHLSPRPEE---PHLSPQAEEPHLSPQPE 775
Query: 525 NPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQ------ETVPEFPCTFLPPTPAPTPP 578
PCL + E P +S SPQ VPE PC P + P
Sbjct: 776 EPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSP 835
Query: 579 R-------PPPGPATLAP--SRPLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTLSVR 629
+ P P + L+P +P L P+ E+ PP G + +L P PG S+
Sbjct: 836 QSEEPCLSPRPEESHLSPELEKPPLSPRPEK--PPEEPG-QCPAPEELPLFPPPGEPSLS 892
Query: 630 VSPPQPILSR-GRP 642
+P LS G P
Sbjct: 893 PLLGEPALSEPGEP 906
Score = 82.8 bits (203), Expect = 1e-15
Identities = 122/447 (27%), Positives = 157/447 (35%), Gaps = 86/447 (19%)
Query: 195 PSREDDLLAPKQAEGRWPPPEQWCKQLFSSVVPVLLGDPEEEPGGRQLLDLNCFLSDISD 254
P ED ++P E PP + + VV L PEE P LS +
Sbjct: 628 PPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESP-----------LSPPPE 676
Query: 255 TLFTMTQSGPSPLQLPPEDAYVGNADMIQPDLTPLQPSLDDFMDISDFFTNSRLPQPPMP 314
T S L PPED+ P+ +P P +D + + LP P P
Sbjct: 677 ESPTSPPPEASRLSPPPEDSPTSPP----PEDSPASPPPEDSLMSLPLEESPLLPLPEEP 732
Query: 315 SNFP--EPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDSSAFL 372
P E P SP + S PE P HLS + + P A
Sbjct: 733 QLCPRSEGPHLSPRPEEPHLSPR--PEEP-------HLSPQAEEPHLSPQPEEPCLCAVP 783
Query: 373 SSDFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQ---EEP 429
L P+ P L P P LH P + P L P P P P + L EEP
Sbjct: 784 EEPHLSPQAEGPHLSPQPEE---LHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEP 840
Query: 430 LFSPR---------------FPFPTVPPA-PGVSPLPAPAA-FPPTPQSVPSP------- 465
SPR P P PP PG P P FPP + SP
Sbjct: 841 CLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPAL 900
Query: 466 --------APTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASP 517
+P P + L P G EP+ P P PP SP A+PP L+P
Sbjct: 901 SEPGEPPLSPLPEELPLSPSG--EPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGE-- 956
Query: 518 PTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTP 577
+ AK + E PL ++ +L +P SP PE CT P P P
Sbjct: 957 -----------LEYPFGAKGDSDPESPL-AAPILETPISPP---PEANCT--DPEPVPPM 999
Query: 578 PRPPPGPATLAPSRPLLV-PKAERLSP 603
PP + + P+ P+L+ P + SP
Sbjct: 1000 ILPPSPGSPVGPASPILMEPLPPQCSP 1026
Score = 63.5 bits (153), Expect = 8e-10
Identities = 94/359 (26%), Positives = 127/359 (35%), Gaps = 50/359 (13%)
Query: 264 PSPLQLPPEDAYVGNADMIQPDLTPLQPSLDDFMDISDFFTNSRLPQPPMPSNFPEPPSF 323
P P + P E + + P +PSL + P P+P P PS
Sbjct: 862 PRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSG 921
Query: 324 SPVVD-SLFSSGTLGPEVPP--ASSAMTHLSGHSRLQARNSCPGPLDSSAFLSSDFL-LP 379
P + L L P + P ++A LS L+ G D + L++ L P
Sbjct: 922 EPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETP 981
Query: 380 EDPKPRL---PPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQE--EPLFSPR 434
P P P PVPP +L PP P P+ P + +L E P SP
Sbjct: 982 ISPPPEANCTDPEPVPPMIL--------------PPSPGSPVGPASPILMEPLPPQCSPL 1027
Query: 435 FPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPI-------ELLPLGYSEPAFGPC 487
VP SP P+ + P P SVPSP + EL + + + C
Sbjct: 1028 LQHSLVPQN---SP-PSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPEC 1083
Query: 488 FSM-PRGKPPAPSPRGQKASP-PTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEPPL 545
++ P P PSP G + P P+ APA P ++PE P
Sbjct: 1084 PALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGS 1143
Query: 546 VSSTLLRSPG--SPQETVPEFPCTFLP----------PTPAPTPPRPP--PGPATLAPS 590
++S L SP P+E P P P P PR P P P TL S
Sbjct: 1144 LASELKGSPVLLDPEELAPVTPMEVYPECKQTAGQGSPCEEQEEPRAPVAPTPPTLIKS 1202
Score = 56.6 bits (135), Expect = 9e-08
Identities = 106/369 (28%), Positives = 131/369 (35%), Gaps = 99/369 (26%)
Query: 334 GTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDSSAFLSSDFLLPEDPKPRLPPPPVPP 393
G LG PP ++A T G + P L +SA FL P P +P P P
Sbjct: 2111 GALGS--PPPAAAPTIFIGSP------TTPAGLSTSA---DGFLKP--PAGSVPGPDSPG 2157
Query: 394 PL-LHYPP--PAKVPGLEPCPPPPFPPMAP--PTALLQEEPLFSPRFPFPT----VPPAP 444
L L PP PA+VP +P P P+ P PTA P P +P PT PP
Sbjct: 2158 ELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTA-----PPTYPPYPSPTGAPAQPPML 2212
Query: 445 GVSPLPA---PAAFPPTPQSVPSPAP-TPFPIELLPLGYSEPAFGPCFSMPR-GKPPAPS 499
G S P P F TP P P TP P + +P C S+ P +P
Sbjct: 2213 GASSRPGAGQPGEFHTTPPGTPRHQPSTPDP-------FLKPR---CPSLDNLAVPESPG 2262
Query: 500 PRGQKASPPTLAPA---------------------TASPPTTAGSNNPCL-TQL--LTAA 535
G KAS P L+P + PP ++P T L L
Sbjct: 2263 VGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELK 2322
Query: 536 KPEQALEP--PLVSSTLLRSPG---SPQE---------TVPEFPCTFLP---------PT 572
P+ P P S +SPG PQE + P P F P P
Sbjct: 2323 TPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPP 2382
Query: 573 PAPTPPRPPPGPATLAPSRPLLVPKAERL--SPPAPSGSERRLSGDLSSMPGPGTLSVRV 630
P P PPP P R L R+ SP + S S+ L+ P LS
Sbjct: 2383 LTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLT--------PRPLSAEA 2434
Query: 631 SPPQPILSR 639
P P+ R
Sbjct: 2435 FCPSPVTPR 2443
Score = 53.5 bits (127), Expect = 8e-07
Identities = 79/303 (26%), Positives = 101/303 (33%), Gaps = 69/303 (22%)
Query: 377 LLPEDPKPR---LPPPPVPPPLLH---YPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPL 430
L P++P P P PP P + Y P P L P P PP PP + P
Sbjct: 2347 LRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPP-----PPESCCALPPR 2401
Query: 431 FSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPF-PIELLPLGYSEPA------ 483
P PF VP +P S + + P P S + P+P P P YS P
Sbjct: 2402 SLPSDPFSRVPASPQ-SQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSR 2460
Query: 484 --FGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQAL 541
F P PR +PP + + + +L AG ++ + P
Sbjct: 2461 DPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVR 2520
Query: 542 EPPLVSSTLLRSP---------GSPQETVPEFPCTFLPPT--------PAPTPPRP---- 580
P + SP G P P P LPP P PT +P
Sbjct: 2521 SPGTGAFVGTPSPMRFTFPQAVGEPS-LKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTN 2579
Query: 581 -------------PPGPAT--------LAPSRPLLVPKAERLSPPAPSGSERRLSGDLSS 619
P GP++ L+P RP V L PPAP GS LS S
Sbjct: 2580 YTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSV-----LPPPAPDGSLPYLSHGASQ 2634
Query: 620 MPG 622
G
Sbjct: 2635 RSG 2637
Score = 52.4 bits (124), Expect = 2e-06
Identities = 80/340 (23%), Positives = 109/340 (32%), Gaps = 82/340 (24%)
Query: 332 SSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDSSAFLSSDFLLPEDP---KPRL-- 386
S G LG +S++ HL + D ++ + L P+ P +P
Sbjct: 4115 SHGQLGSGSSSEASSVPHLLAQPSVSLG-------DQPGSMTQNLLGPQQPMLERPMQNN 4167
Query: 387 --PPPPVPPPLLHYPPPAKVPGLEP-------------CPPPPFPPMAPPT-----ALLQ 426
P PP P P+L G+ P P ++P ALL
Sbjct: 4168 TGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLM 4227
Query: 427 EEPLFSPRFPFPTVP-PAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYSEPAFG 485
+ L + T P PG P PQ P P P++ L G
Sbjct: 4228 QRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAG------- 4280
Query: 486 PCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEPPL 545
P+G P P+P G ++ P L P +PP
Sbjct: 4281 ---PRPQGPPRLPAPPGALSTGPVLGPVHPTPP--------------------------- 4310
Query: 546 VSSTLLRSPGSPQETVPEFPCTF-LPPTPAPTPPR-PPPGPATLAPSRPLLVPKAERLSP 603
P SPQE P+ P P + PT + PP P T P P L P R+SP
Sbjct: 4311 --------PSSPQE--PKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSP 4360
Query: 604 PAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPD 643
A ++ S L P L+ P Q L G D
Sbjct: 4361 AAAQLADTLFSKGLGPWDPPDNLAETQKPEQSSLVPGHLD 4400
Score = 44.7 bits (104), Expect = 4e-04
Identities = 56/209 (26%), Positives = 66/209 (31%), Gaps = 57/209 (27%)
Query: 440 VPPAPGVSPLPAPAAFP------PT---------------------------------PQ 460
+PP PG P PAA P PT P
Sbjct: 2106 IPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPP 2165
Query: 461 SVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTT 520
VP+ P+ P L P EP F + P PP PSP G A PP L ++
Sbjct: 2166 QVPAQVPSQDPFGLAPAYPLEPRFP---TAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQ 2222
Query: 521 AGS--NNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPP 578
G P T + P+ L+P R P VPE P P
Sbjct: 2223 PGEFHTTPPGTPRHQPSTPDPFLKP--------RCPSLDNLAVPESPGVGGGKASEPLLS 2274
Query: 579 RPPPGPATLAPSRPLLVPKAERLSPPAPS 607
PP G SR L K E L +PS
Sbjct: 2275 PPPFG-----ESRKALEVKKEELGASSPS 2298
Score = 40.0 bits (92), Expect = 0.009
Identities = 58/233 (24%), Positives = 71/233 (30%), Gaps = 46/233 (19%)
Query: 390 PVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPL 449
P+ P P + GL P PPP +AP P P P P P
Sbjct: 2330 PLTPRASQVEPQSPGLGLRPQEPPPAQALAP-------SPPSHPDIFRPGSYTDPYAQPP 2382
Query: 450 PAPAAFPPTPQSVPSPAPTPFPIE------------------LLPLGYSEPAFGPCFSMP 491
P PP P+S + P P + L P S AF P P
Sbjct: 2383 LTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTP 2442
Query: 492 RGKPPAP------SPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTA--------AKP 537
R + P P P+ + P P PP A L A A P
Sbjct: 2443 RFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGP 2502
Query: 538 EQALEPPLVSS---TLLRSPGSPQETVPEFPCTFLPP----TPAPTPPRPPPG 583
L + S +RSPG+ P F P P+ PP P PG
Sbjct: 2503 AGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPG 2555
Score = 38.1 bits (87), Expect = 0.034
Identities = 24/66 (36%), Positives = 26/66 (39%), Gaps = 6/66 (9%)
Query: 392 PPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPA 451
PPP PPP+ P P P P P L EPL P P P + S P
Sbjct: 4909 PPPEEPSPPPS------PLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPK 4962
Query: 452 PAAFPP 457
P A PP
Sbjct: 4963 PRARPP 4968
Score = 37.0 bits (84), Expect = 0.076
Identities = 80/332 (24%), Positives = 105/332 (31%), Gaps = 65/332 (19%)
Query: 227 PVLLGDPEEEPGGRQLLDLNCFLSDISDTLFTMTQSGPSPLQLPPEDAYVGNADMIQPDL 286
P LG + G L L D+ T P Q+ P+ +G P
Sbjct: 2301 PPNLGFVDSPSSGTHLGGLELKTPDVFKAPLT-----PRASQVEPQSPGLGLRPQEPPPA 2355
Query: 287 TPLQPSLDDFMDI------SDFFTNSRL---PQPPMPSNFPEPPSFSPVVDSLFSSGTLG 337
L PS DI +D + L PQPP P + P S D FS
Sbjct: 2356 QALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDP-FSRVPAS 2414
Query: 338 PEVPPASSAMTHLSGHSRLQARNSCPGPLDS------------SAFLSSDFLLPEDPKPR 385
P+ SS+ + L+ L A CP P+ S S D P PR
Sbjct: 2415 PQ--SQSSSQSPLTPRP-LSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPR 2471
Query: 386 LPPPPVP----------------PPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQE-- 427
PP V P L P ++ P PP +P T
Sbjct: 2472 PQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTP 2531
Query: 428 ------------EPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPT-PFPIEL 474
EP P P P +PP G++ P PQS T F
Sbjct: 2532 SPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSG 2591
Query: 475 LPLGYSEPAFGPCFSMPRGKPPA----PSPRG 502
PLG S + G + + +PP+ P+P G
Sbjct: 2592 SPLGPSSGSTGESYGLSPLRPPSVLPPPAPDG 2623
Score = 37.0 bits (84), Expect = 0.076
Identities = 36/124 (29%), Positives = 44/124 (35%), Gaps = 31/124 (25%)
Query: 390 PVPPPLLHYPPPAKVPGLEP---CPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGV 446
P P P + V L+ PPP P PP SP P P PP +
Sbjct: 4884 PAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPP----------SPLAPSPASPPTEPL 4933
Query: 447 SPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKAS 506
LP P P P+P LPL S + P PR +PP G+ +
Sbjct: 4934 VELPTEPLAEP-------PVPSP-----LPLASSPESARP---KPRARPP---EEGEDSR 4975
Query: 507 PPTL 510
PP L
Sbjct: 4976 PPRL 4979
Score = 36.2 bits (82), Expect = 0.13
Identities = 106/470 (22%), Positives = 154/470 (32%), Gaps = 117/470 (24%)
Query: 300 SDFFTNSRLPQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQAR 359
S T + L PP P + PP+ P V +G V P+ H + AR
Sbjct: 4608 SQLLTKNNLSNPPTPPS-SLPPTPPPSVQQKMVNG-----VTPSEELGEHPKDAA--SAR 4659
Query: 360 NSCPGPLDSSAFLSSDFL--LPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCP-----P 412
+S D+S S D L LP P + + P + VP P
Sbjct: 4660 DSERALRDTSEVKSLDLLAALPTPPHNQTEDVRMESDEDSDSPDSIVPASSPESILGEEA 4719
Query: 413 PPFPPMAPPTALLQEEPLFSPRFPF---PTVPPAPGVSP-----LPAPAAFPPTP----- 459
P FP + QE+ SP P ++P P P L P P T
Sbjct: 4720 PRFPHLGSGR-WEQEDRALSPVIPLIPRASIPVFPDTKPYGALGLEVPGKLPVTTWEKGK 4778
Query: 460 ------------------------------QSVPSPAPTPFPIELLPLGYSEPAFGPCFS 489
+P+ FP G +EP G
Sbjct: 4779 GSEVSVMLTVSAAAAKNLNGVMVAVAELLSMKIPNSYEVLFPESPARAG-TEPKKGEAEG 4837
Query: 490 MPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEPPL---- 545
P GK + P L A P + + LL P A EPP
Sbjct: 4838 -PGGKEKGLEGKSPDTGPDWLKQFDAVLPGYTLKSQLDILSLLKQESP--APEPPTQHSY 4894
Query: 546 ---VSSTLLRSPGSPQETVPEFPCTFLPPTP-APTPPRPPPGPATLAPSRPLLVPKAERL 601
VS+ +R +P PE P PP+P AP+P PP P P+ PL
Sbjct: 4895 TYNVSNLDVRQLSAPP---PEEPSP--PPSPLAPSPASPPTEPLVELPTEPL-------A 4942
Query: 602 SPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDSNKTENR--RITHISAEQ 659
PP PS P P S + P+P R RP ++R R+ +
Sbjct: 4943 EPPVPS-------------PLPLASSPESARPKP---RARPPEEGEDSRPPRLKKWKGVR 4986
Query: 660 KRRFNIKLGFDTLHGLVSTLSAQPSLKERAGLQEEAQQLRDEIEELNAAI 709
+R + L ++++ +G QE+ +++ + +E+L A+
Sbjct: 4987 WKRLRLLL----------------TIQKGSGRQEDEREVAEFMEQLGTAL 5020
Score = 35.0 bits (79), Expect = 0.29
Identities = 50/186 (26%), Positives = 70/186 (37%), Gaps = 40/186 (21%)
Query: 499 SPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQ 558
SP+ Q+ L P + P S+ L L EQ P VSS P + Q
Sbjct: 3986 SPQQQQQQQVALGPGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQ 4045
Query: 559 ------ETVPEFPCTFLPPTPAPT----------PPRPPPGPATLAPSRPLLVPKAER-- 600
T PE T P P+ P+P P P++L PL +P ++
Sbjct: 4046 GGPLAIGTTPESMAT-EPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQ 4104
Query: 601 --LSPPAPSGSERRL----SGDLSSMP------------GPGTLSVR-VSPPQPILSRGR 641
L A GS +L S + SS+P PG+++ + P QP+L R
Sbjct: 4105 VSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLE--R 4162
Query: 642 PDSNKT 647
P N T
Sbjct: 4163 PMQNNT 4168
Score = 30.4 bits (67), Expect = 7.1
Identities = 55/213 (25%), Positives = 76/213 (35%), Gaps = 36/213 (16%)
Query: 332 SSGTLGPE----VPPASSAMTHLSG----HSRLQARNSCPG--PLDSSAFLSSDFLLPED 381
++G +GP P+S A LS + Q ++S G P S + P D
Sbjct: 2710 AAGAVGPPGSWGAEPSSPAFEQLSRGQTPFAGTQDKSSLVGLPPSKLSGPILGPGSFPSD 2769
Query: 382 PKPRLPPPPVPPPLLHYPPPAKVPGLEP-CPPPPFPPMAP-------------PTALLQE 427
+ PPPP P + V G + P+P P TA
Sbjct: 2770 DRLSRPPPPATPSSMDVNSRQLVGGSQAFYQRAPYPGSLPLQQQQQQLWQQQQATAATSM 2829
Query: 428 EPLFSPRFPFPTVPPAPGVSPLPAPAA-----FPPTPQSVPSPAPTPFPIELLPLGYS-E 481
S RFP T P G L +P A P + VP PA P + + L ++ +
Sbjct: 2830 RFAMSARFP-STPGPELGRQALGSPLAGISTRLPGPGEPVPGPAG---PAQFIELRHNVQ 2885
Query: 482 PAFGPCFSMPRGKPPAPSPRGQKAS--PPTLAP 512
GP + G+ P PR S P LAP
Sbjct: 2886 KGLGPGGTPFPGQGPPQRPRFYPVSEDPHRLAP 2918
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 89.4 bits (220), Expect = 1e-17
Identities = 101/399 (25%), Positives = 145/399 (36%), Gaps = 57/399 (14%)
Query: 260 TQSGPSPLQLPPEDAYVGNADMIQPDLTPLQPSLDDFMDISDFFTNSRLPQPPMPSNFPE 319
T S P+ PP + + P TP P+ + P PP+ +
Sbjct: 1398 TPSPPTTTPSPPPTS----TTTLPPTTTPSPPTTTTTTP-----PPTTTPSPPITTTTTP 1448
Query: 320 PPSFSPVVDSLFSSGTLGPEV----PPASSAMTHLSGHSRLQARNSCPGPLDSSAFLSSD 375
PP+ +P S+ T P PP ++ + S + P P + + ++
Sbjct: 1449 PPTTTP--SPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTT 1506
Query: 376 FLLPEDPKPRLPP-----PPV-----PPPLLHYPPPAKVPGLEPCP----PPPFPPMAPP 421
+ P LPP PP PPP PP P P PP P PP
Sbjct: 1507 PITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPP 1566
Query: 422 TALLQEEPLFSPRFPFPTVPPAPGV---SPLPAPAAFPP-TPQSVPSPAPTPFPIELLPL 477
T P +P P T P P + +P P PP T + P P TP P P+
Sbjct: 1567 TTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPI 1626
Query: 478 GYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKP 537
+ P ++P P+P P PPT P SPPTT + P + T P
Sbjct: 1627 --TPPT--STTTLPPTTTPSPPPTTTTTPPPTTTP---SPPTTTTPSPP----ITTTTTP 1675
Query: 538 EQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLL-VP 596
PP +P SP T P P T + TP+PT P T PS P
Sbjct: 1676 -----PPTT------TPSSPITTTPSPPTTTM-TTPSPTTTPSSPITTTTTPSSTTTPSP 1723
Query: 597 KAERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQP 635
++ P+P+ + + ++++P T S + P P
Sbjct: 1724 PPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLP 1762
Score = 83.6 bits (205), Expect = 7e-16
Identities = 84/308 (27%), Positives = 104/308 (33%), Gaps = 48/308 (15%)
Query: 382 PKPRLPPPPVPPPLLHYPPPAKVPGLEPCP---PPPFPPMAPPTALLQEEPLFSPRFPFP 438
P + P PP PPP L P PP PP P+ + P P
Sbjct: 1391 PMDKCITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPP 1450
Query: 439 TVPPAPGVS----PLPAPAAFPPT-----PQSVPS----------PAPTPFPIELLPLGY 479
T P+P +S P P PPT P + PS P TP P P+
Sbjct: 1451 TTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPI-- 1508
Query: 480 SEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQ 539
+ PA ++P P+P PPT P SPPTT P T T P
Sbjct: 1509 TPPA--STTTLPPTTTPSPPTTTTTTPPPTTTP---SPPTTTPITPPTST---TTLPPTT 1560
Query: 540 ALEPPLVSSTL---LRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVP 596
PP ++T +P P T P P T TP PT PP T P P P
Sbjct: 1561 TPSPPPTTTTTPPPTTTPSPPTTTTPS-PPTITTTTPPPTTTPSPPTTTTTTPP-PTTTP 1618
Query: 597 KAERLSPPAPSGSERRLSGDLSSMPGPGTLS-----------VRVSPPQPILSRGRPDSN 645
+P P S L + P P T + +P PI + P
Sbjct: 1619 SPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPT 1678
Query: 646 KTENRRIT 653
T + IT
Sbjct: 1679 TTPSSPIT 1686
Score = 82.0 bits (201), Expect = 2e-15
Identities = 89/358 (24%), Positives = 122/358 (34%), Gaps = 45/358 (12%)
Query: 253 SDTLFTMTQSGPSPLQLPPEDAYVGNADMIQPDLTPLQPSLDDFMDISDFFTNSRLPQPP 312
S + T T P+ PP + P TP P+ + + P
Sbjct: 1439 SPPITTTTTPPPTTTPSPP----ISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTP 1494
Query: 313 MPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDSSAFL 372
P+ P PP+ +P+ S+ TL P P+ T + P P + +
Sbjct: 1495 PPTTTPSPPTTTPITPPA-STTTLPPTTTPSPPTTT-----------TTTPPPTTTPSPP 1542
Query: 373 SSDFLLPEDPKPRLPPP--PVPPPLLHYPPPAKVPGLEPCPPPPFPPM----APPTALLQ 426
++ + P LPP P PPP PP P P PP PP
Sbjct: 1543 TTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTP 1602
Query: 427 EEPLFSPRFPFPTVPPAPG----VSPLPAPAAFPPTPQSVPSPAPTPF---PIELLPLGY 479
P + P PT P+P ++P + PPT + PSP PT P P
Sbjct: 1603 SPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPT--TTPSPPPTTTTTPPPTTTPSPP 1660
Query: 480 SEPAFGPCFSMPRGKPPAPSPRGQ---KASPPTLAPATASPPTTAGSNNPCLTQLLTAAK 536
+ P + PP +P SPPT T SP TT S + T
Sbjct: 1661 TTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSS------PITTTTT 1714
Query: 537 PEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPT----PAPTPPRPP-PGPATLAP 589
P P +T+ + + P T LPPT P T P PP P T +P
Sbjct: 1715 PSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSP 1772
Score = 76.6 bits (187), Expect = 9e-14
Identities = 90/348 (25%), Positives = 117/348 (33%), Gaps = 61/348 (17%)
Query: 258 TMTQSGPSPLQLPPEDAYVGNADMIQPDLTPLQPSLDDFMDISDFFT--NSRLPQPPMPS 315
T T S P+ PP P TP P+ + T + P PP +
Sbjct: 1474 TTTPSPPTTTPSPPTTT----TTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTT 1529
Query: 316 NFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDSSAFLSSD 375
PP+ +P S T P PP S+ + P P ++
Sbjct: 1530 TTTPPPTTTP------SPPTTTPITPPTSTTTL---------PPTTTPSPPPTTTTTPPP 1574
Query: 376 FLLPEDPKPRLPPPPV-----PPPLLHYPPPAKVPGLEPCPPPPFPP----MAPPTALLQ 426
P P P PP PPP PP P P PP + PPT+
Sbjct: 1575 TTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTT 1634
Query: 427 EEPLFSPR-------FPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPF-PIELLPLG 478
P +P P PT P+P + P+P P T + P P TP PI P
Sbjct: 1635 LPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSP---PITTTTTPPPTTTPSSPITTTP-- 1689
Query: 479 YSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPE 538
S P PSP +SP T T +P +T + P T +T P
Sbjct: 1690 ----------SPPTTTMTTPSPTTTPSSPIT---TTTTPSSTTTPSPPPTT--MTTPSPT 1734
Query: 539 QALEPPLVSSTLL--RSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGP 584
PP + T L + SP T P P + PPT +P P P
Sbjct: 1735 TTPSPPTTTMTTLPPTTTSSPLTTTP-LPPSITPPTFSPFSTTTPTTP 1781
Score = 57.8 bits (138), Expect = 4e-08
Identities = 67/279 (24%), Positives = 90/279 (32%), Gaps = 45/279 (16%)
Query: 412 PPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFP 471
P P P T + +P P PT P +P+ PTP + PT P
Sbjct: 3981 PTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 4039
Query: 472 IELL--------PLGYSEPAFGPCFSMPRGKPPAPSPRGQKA--SPPTLAPATASP-PTT 520
I P G P P + P P+P G + + P T +P PT
Sbjct: 4040 ITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 4098
Query: 521 AGSNNPCLTQLLTAAKPEQALEP---------PLVSSTLLRSPGSP-----QETVPEFPC 566
G+ P T + T P P+ ++T + +P T P
Sbjct: 4099 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 4158
Query: 567 TFLPPTPAP-----------------TPPRPPPGPATLAPSRPLLVPKAE-RLSPPAPSG 608
T + PTP P TP P G T P+ P AE S P P
Sbjct: 4159 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPES 4218
Query: 609 SERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDSNKT 647
S + S SS T + PP ++ P S T
Sbjct: 4219 STPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPT 4257
Score = 55.1 bits (131), Expect = 3e-07
Identities = 60/227 (26%), Positives = 77/227 (33%), Gaps = 24/227 (10%)
Query: 412 PPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFP 471
P P P T + +P P PT P +P+ PTP + PT P
Sbjct: 4096 PTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 4154
Query: 472 IELL--------PLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGS 523
I P G P P + P P+P G + PPT +TA S
Sbjct: 4155 ITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTGPPTHT-STAPIAELTTS 4212
Query: 524 NNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTP-APTPPR--- 579
N P + + + ++ PL ST L S P E T P TP APT
Sbjct: 4213 NPPPES---STPQTSRSTSSPLTESTTLLSTLPP---AIEMTSTAPPSTPTAPTTTSGGH 4266
Query: 580 ---PPPGPATLAPSRPLLVPKAERLSPPAPSGSERRLSGDLSSMPGP 623
PPP T P P S P PS + + + P P
Sbjct: 4267 TLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTP 4313
Score = 53.5 bits (127), Expect = 8e-07
Identities = 55/209 (26%), Positives = 78/209 (37%), Gaps = 31/209 (14%)
Query: 421 PTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYS 480
PT + P +P TV P P + P P T + +P PT P G
Sbjct: 4119 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-------PTGTQ 4171
Query: 481 EPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQA 540
P P + P P+P G + PPT T++ P + +L T+ P ++
Sbjct: 4172 TPTTTP-ITTTTTVTPTPTPTGTQTGPPT---HTSTAP---------IAELTTSNPPPES 4218
Query: 541 LEPPLVSSTLLRSPGSPQETVPEFPCTFLPPT---PAPTPPRPPPGPATLAPSRPLLVPK 597
P ST SP + T+ + LPP + PP P P T + L P
Sbjct: 4219 STPQTSRST--SSPLTESTTL----LSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPP 4272
Query: 598 AERLSPPAPSGSERRLSGDLSSMPGPGTL 626
+ SPP R + SS P P T+
Sbjct: 4273 STTTSPPGT--PTRGTTTGSSSAPTPSTV 4299
Score = 50.4 bits (119), Expect = 7e-06
Identities = 55/239 (23%), Positives = 79/239 (33%), Gaps = 42/239 (17%)
Query: 412 PPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFP 471
P P P T + +P P PT P +P+ PTP + PT P
Sbjct: 1957 PTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2015
Query: 472 IELL--------PLGYSEPAFGPCFSMPRGKPPAPSPRGQKA--SPPTLAPATASP-PTT 520
I P G P P + P P+P G + + P T +P PT
Sbjct: 2016 ITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2074
Query: 521 AGSNNPCLTQLLTAAKPEQALEP---------PLVSSTLLRSPGSP-----QETVPEFPC 566
G+ P T + T P P+ ++T + +P T P
Sbjct: 2075 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2134
Query: 567 TFLPPTPAPTPPRPP------------PGPATLAPSRPLLVP--KAERLSP-PAPSGSE 610
T + PTP PT + P P P P P ++P P P+G++
Sbjct: 2135 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2193
Score = 50.4 bits (119), Expect = 7e-06
Identities = 55/239 (23%), Positives = 79/239 (33%), Gaps = 42/239 (17%)
Query: 412 PPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFP 471
P P P T + +P P PT P +P+ PTP + PT P
Sbjct: 2141 PTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2199
Query: 472 IELL--------PLGYSEPAFGPCFSMPRGKPPAPSPRGQKA--SPPTLAPATASP-PTT 520
I P G P P + P P+P G + + P T +P PT
Sbjct: 2200 ITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2258
Query: 521 AGSNNPCLTQLLTAAKPEQALEP---------PLVSSTLLRSPGSP-----QETVPEFPC 566
G+ P T + T P P+ ++T + +P T P
Sbjct: 2259 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2318
Query: 567 TFLPPTPAPTPPRPP------------PGPATLAPSRPLLVP--KAERLSP-PAPSGSE 610
T + PTP PT + P P P P P ++P P P+G++
Sbjct: 2319 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2377
Score = 50.4 bits (119), Expect = 7e-06
Identities = 55/239 (23%), Positives = 79/239 (33%), Gaps = 42/239 (17%)
Query: 412 PPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFP 471
P P P T + +P P PT P +P+ PTP + PT P
Sbjct: 2325 PTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2383
Query: 472 IELL--------PLGYSEPAFGPCFSMPRGKPPAPSPRGQKA--SPPTLAPATASP-PTT 520
I P G P P + P P+P G + + P T +P PT
Sbjct: 2384 ITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2442
Query: 521 AGSNNPCLTQLLTAAKPEQALEP---------PLVSSTLLRSPGSP-----QETVPEFPC 566
G+ P T + T P P+ ++T + +P T P
Sbjct: 2443 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2502
Query: 567 TFLPPTPAPTPPRPP------------PGPATLAPSRPLLVP--KAERLSP-PAPSGSE 610
T + PTP PT + P P P P P ++P P P+G++
Sbjct: 2503 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2561
Score = 50.4 bits (119), Expect = 7e-06
Identities = 55/239 (23%), Positives = 79/239 (33%), Gaps = 42/239 (17%)
Query: 412 PPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFP 471
P P P T + +P P PT P +P+ PTP + PT P
Sbjct: 2509 PTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2567
Query: 472 IELL--------PLGYSEPAFGPCFSMPRGKPPAPSPRGQKA--SPPTLAPATASP-PTT 520
I P G P P + P P+P G + + P T +P PT
Sbjct: 2568 ITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2626
Query: 521 AGSNNPCLTQLLTAAKPEQALEP---------PLVSSTLLRSPGSP-----QETVPEFPC 566
G+ P T + T P P+ ++T + +P T P
Sbjct: 2627 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2686
Query: 567 TFLPPTPAPTPPRPP------------PGPATLAPSRPLLVP--KAERLSP-PAPSGSE 610
T + PTP PT + P P P P P ++P P P+G++
Sbjct: 2687 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2745
Score = 50.4 bits (119), Expect = 7e-06
Identities = 55/239 (23%), Positives = 79/239 (33%), Gaps = 42/239 (17%)
Query: 412 PPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFP 471
P P P T + +P P PT P +P+ PTP + PT P
Sbjct: 2693 PTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2751
Query: 472 IELL--------PLGYSEPAFGPCFSMPRGKPPAPSPRGQKA--SPPTLAPATASP-PTT 520
I P G P P + P P+P G + + P T +P PT
Sbjct: 2752 ITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2810
Query: 521 AGSNNPCLTQLLTAAKPEQALEP---------PLVSSTLLRSPGSP-----QETVPEFPC 566
G+ P T + T P P+ ++T + +P T P
Sbjct: 2811 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2870
Query: 567 TFLPPTPAPTPPRPP------------PGPATLAPSRPLLVP--KAERLSP-PAPSGSE 610
T + PTP PT + P P P P P ++P P P+G++
Sbjct: 2871 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2929
Score = 50.4 bits (119), Expect = 7e-06
Identities = 55/239 (23%), Positives = 79/239 (33%), Gaps = 42/239 (17%)
Query: 412 PPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFP 471
P P P T + +P P PT P +P+ PTP + PT P
Sbjct: 2877 PTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2935
Query: 472 IELL--------PLGYSEPAFGPCFSMPRGKPPAPSPRGQKA--SPPTLAPATASP-PTT 520
I P G P P + P P+P G + + P T +P PT
Sbjct: 2936 ITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2994
Query: 521 AGSNNPCLTQLLTAAKPEQALEP---------PLVSSTLLRSPGSP-----QETVPEFPC 566
G+ P T + T P P+ ++T + +P T P
Sbjct: 2995 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3054
Query: 567 TFLPPTPAPTPPRPP------------PGPATLAPSRPLLVP--KAERLSP-PAPSGSE 610
T + PTP PT + P P P P P ++P P P+G++
Sbjct: 3055 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3113
Score = 50.4 bits (119), Expect = 7e-06
Identities = 55/239 (23%), Positives = 79/239 (33%), Gaps = 42/239 (17%)
Query: 412 PPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFP 471
P P P T + +P P PT P +P+ PTP + PT P
Sbjct: 3061 PTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3119
Query: 472 IELL--------PLGYSEPAFGPCFSMPRGKPPAPSPRGQKA--SPPTLAPATASP-PTT 520
I P G P P + P P+P G + + P T +P PT
Sbjct: 3120 ITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3178
Query: 521 AGSNNPCLTQLLTAAKPEQALEP---------PLVSSTLLRSPGSP-----QETVPEFPC 566
G+ P T + T P P+ ++T + +P T P
Sbjct: 3179 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3238
Query: 567 TFLPPTPAPTPPRPP------------PGPATLAPSRPLLVP--KAERLSP-PAPSGSE 610
T + PTP PT + P P P P P ++P P P+G++
Sbjct: 3239 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3297
Score = 50.4 bits (119), Expect = 7e-06
Identities = 55/239 (23%), Positives = 79/239 (33%), Gaps = 42/239 (17%)
Query: 412 PPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFP 471
P P P T + +P P PT P +P+ PTP + PT P
Sbjct: 3245 PTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3303
Query: 472 IELL--------PLGYSEPAFGPCFSMPRGKPPAPSPRGQKA--SPPTLAPATASP-PTT 520
I P G P P + P P+P G + + P T +P PT
Sbjct: 3304 ITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3362
Query: 521 AGSNNPCLTQLLTAAKPEQALEP---------PLVSSTLLRSPGSP-----QETVPEFPC 566
G+ P T + T P P+ ++T + +P T P
Sbjct: 3363 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3422
Query: 567 TFLPPTPAPTPPRPP------------PGPATLAPSRPLLVP--KAERLSP-PAPSGSE 610
T + PTP PT + P P P P P ++P P P+G++
Sbjct: 3423 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3481
Score = 50.4 bits (119), Expect = 7e-06
Identities = 55/239 (23%), Positives = 79/239 (33%), Gaps = 42/239 (17%)
Query: 412 PPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFP 471
P P P T + +P P PT P +P+ PTP + PT P
Sbjct: 3429 PTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3487
Query: 472 IELL--------PLGYSEPAFGPCFSMPRGKPPAPSPRGQKA--SPPTLAPATASP-PTT 520
I P G P P + P P+P G + + P T +P PT
Sbjct: 3488 ITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3546
Query: 521 AGSNNPCLTQLLTAAKPEQALEP---------PLVSSTLLRSPGSP-----QETVPEFPC 566
G+ P T + T P P+ ++T + +P T P
Sbjct: 3547 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3606
Query: 567 TFLPPTPAPTPPRPP------------PGPATLAPSRPLLVP--KAERLSP-PAPSGSE 610
T + PTP PT + P P P P P ++P P P+G++
Sbjct: 3607 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3665
Score = 50.4 bits (119), Expect = 7e-06
Identities = 55/239 (23%), Positives = 79/239 (33%), Gaps = 42/239 (17%)
Query: 412 PPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFP 471
P P P T + +P P PT P +P+ PTP + PT P
Sbjct: 3613 PTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3671
Query: 472 IELL--------PLGYSEPAFGPCFSMPRGKPPAPSPRGQKA--SPPTLAPATASP-PTT 520
I P G P P + P P+P G + + P T +P PT
Sbjct: 3672 ITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3730
Query: 521 AGSNNPCLTQLLTAAKPEQALEP---------PLVSSTLLRSPGSP-----QETVPEFPC 566
G+ P T + T P P+ ++T + +P T P
Sbjct: 3731 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3790
Query: 567 TFLPPTPAPTPPRPP------------PGPATLAPSRPLLVP--KAERLSP-PAPSGSE 610
T + PTP PT + P P P P P ++P P P+G++
Sbjct: 3791 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3849
Score = 50.4 bits (119), Expect = 7e-06
Identities = 55/239 (23%), Positives = 79/239 (33%), Gaps = 42/239 (17%)
Query: 412 PPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFP 471
P P P T + +P P PT P +P+ PTP + PT P
Sbjct: 3797 PTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3855
Query: 472 IELL--------PLGYSEPAFGPCFSMPRGKPPAPSPRGQKA--SPPTLAPATASP-PTT 520
I P G P P + P P+P G + + P T +P PT
Sbjct: 3856 ITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3914
Query: 521 AGSNNPCLTQLLTAAKPEQALEP---------PLVSSTLLRSPGSP-----QETVPEFPC 566
G+ P T + T P P+ ++T + +P T P
Sbjct: 3915 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3974
Query: 567 TFLPPTPAPTPPRPP------------PGPATLAPSRPLLVP--KAERLSP-PAPSGSE 610
T + PTP PT + P P P P P ++P P P+G++
Sbjct: 3975 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 4033
Score = 49.3 bits (116), Expect = 1e-05
Identities = 58/242 (23%), Positives = 82/242 (33%), Gaps = 50/242 (20%)
Query: 409 PCPPPPFP-----PMAP-PTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSV 462
P PP P + P PT + P +P TV P P + P P T +
Sbjct: 1893 PTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 1952
Query: 463 PSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATAS-----P 517
+P PT P G P P + P P+P G + PT P T +
Sbjct: 1953 VTPTPT-------PTGTQTPTTTP-ITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPT 2002
Query: 518 PTTAGSNNPCLTQLLTAAKPEQALEP---------PLVSSTLLRSPGSP-----QETVPE 563
PT G+ P T + T P P+ ++T + +P T P
Sbjct: 2003 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2062
Query: 564 FPCTFLPPTPAPTPPRPP------------PGPATLAPSRPLLVP--KAERLSP-PAPSG 608
T + PTP PT + P P P P P ++P P P+G
Sbjct: 2063 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2122
Query: 609 SE 610
++
Sbjct: 2123 TQ 2124
Score = 48.5 bits (114), Expect = 3e-05
Identities = 53/224 (23%), Positives = 76/224 (33%), Gaps = 44/224 (19%)
Query: 421 PTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYS 480
PT + P +P TV P P + P P T + +P PT P G
Sbjct: 2095 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-------PTGTQ 2147
Query: 481 EPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATAS-----PPTTAGSNNPCLTQLLTAA 535
P P + P P+P G + PT P T + PT G+ P T + T
Sbjct: 2148 TPTTTP-ITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2204
Query: 536 KPEQALEP---------PLVSSTLLRSPGSP-----QETVPEFPCTFLPPTPAPTPPRPP 581
P P+ ++T + +P T P T + PTP PT + P
Sbjct: 2205 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2264
Query: 582 ------------PGPATLAPSRPLLVP--KAERLSP-PAPSGSE 610
P P P P ++P P P+G++
Sbjct: 2265 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2308
Score = 48.5 bits (114), Expect = 3e-05
Identities = 53/224 (23%), Positives = 76/224 (33%), Gaps = 44/224 (19%)
Query: 421 PTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYS 480
PT + P +P TV P P + P P T + +P PT P G
Sbjct: 2279 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-------PTGTQ 2331
Query: 481 EPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATAS-----PPTTAGSNNPCLTQLLTAA 535
P P + P P+P G + PT P T + PT G+ P T + T
Sbjct: 2332 TPTTTP-ITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2388
Query: 536 KPEQALEP---------PLVSSTLLRSPGSP-----QETVPEFPCTFLPPTPAPTPPRPP 581
P P+ ++T + +P T P T + PTP PT + P
Sbjct: 2389 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2448
Query: 582 ------------PGPATLAPSRPLLVP--KAERLSP-PAPSGSE 610
P P P P ++P P P+G++
Sbjct: 2449 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2492
Score = 48.5 bits (114), Expect = 3e-05
Identities = 53/224 (23%), Positives = 76/224 (33%), Gaps = 44/224 (19%)
Query: 421 PTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYS 480
PT + P +P TV P P + P P T + +P PT P G
Sbjct: 2463 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-------PTGTQ 2515
Query: 481 EPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATAS-----PPTTAGSNNPCLTQLLTAA 535
P P + P P+P G + PT P T + PT G+ P T + T
Sbjct: 2516 TPTTTP-ITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2572
Query: 536 KPEQALEP---------PLVSSTLLRSPGSP-----QETVPEFPCTFLPPTPAPTPPRPP 581
P P+ ++T + +P T P T + PTP PT + P
Sbjct: 2573 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2632
Query: 582 ------------PGPATLAPSRPLLVP--KAERLSP-PAPSGSE 610
P P P P ++P P P+G++
Sbjct: 2633 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2676
Score = 48.5 bits (114), Expect = 3e-05
Identities = 53/224 (23%), Positives = 76/224 (33%), Gaps = 44/224 (19%)
Query: 421 PTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYS 480
PT + P +P TV P P + P P T + +P PT P G
Sbjct: 2647 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-------PTGTQ 2699
Query: 481 EPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATAS-----PPTTAGSNNPCLTQLLTAA 535
P P + P P+P G + PT P T + PT G+ P T + T
Sbjct: 2700 TPTTTP-ITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2756
Query: 536 KPEQALEP---------PLVSSTLLRSPGSP-----QETVPEFPCTFLPPTPAPTPPRPP 581
P P+ ++T + +P T P T + PTP PT + P
Sbjct: 2757 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2816
Query: 582 ------------PGPATLAPSRPLLVP--KAERLSP-PAPSGSE 610
P P P P ++P P P+G++
Sbjct: 2817 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2860
Score = 48.5 bits (114), Expect = 3e-05
Identities = 53/224 (23%), Positives = 76/224 (33%), Gaps = 44/224 (19%)
Query: 421 PTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYS 480
PT + P +P TV P P + P P T + +P PT P G
Sbjct: 2831 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-------PTGTQ 2883
Query: 481 EPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATAS-----PPTTAGSNNPCLTQLLTAA 535
P P + P P+P G + PT P T + PT G+ P T + T
Sbjct: 2884 TPTTTP-ITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2940
Query: 536 KPEQALEP---------PLVSSTLLRSPGSP-----QETVPEFPCTFLPPTPAPTPPRPP 581
P P+ ++T + +P T P T + PTP PT + P
Sbjct: 2941 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3000
Query: 582 ------------PGPATLAPSRPLLVP--KAERLSP-PAPSGSE 610
P P P P ++P P P+G++
Sbjct: 3001 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3044
Score = 48.5 bits (114), Expect = 3e-05
Identities = 53/224 (23%), Positives = 76/224 (33%), Gaps = 44/224 (19%)
Query: 421 PTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYS 480
PT + P +P TV P P + P P T + +P PT P G
Sbjct: 3015 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-------PTGTQ 3067
Query: 481 EPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATAS-----PPTTAGSNNPCLTQLLTAA 535
P P + P P+P G + PT P T + PT G+ P T + T
Sbjct: 3068 TPTTTP-ITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3124
Query: 536 KPEQALEP---------PLVSSTLLRSPGSP-----QETVPEFPCTFLPPTPAPTPPRPP 581
P P+ ++T + +P T P T + PTP PT + P
Sbjct: 3125 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3184
Query: 582 ------------PGPATLAPSRPLLVP--KAERLSP-PAPSGSE 610
P P P P ++P P P+G++
Sbjct: 3185 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3228
Score = 48.5 bits (114), Expect = 3e-05
Identities = 53/224 (23%), Positives = 76/224 (33%), Gaps = 44/224 (19%)
Query: 421 PTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYS 480
PT + P +P TV P P + P P T + +P PT P G
Sbjct: 3199 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-------PTGTQ 3251
Query: 481 EPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATAS-----PPTTAGSNNPCLTQLLTAA 535
P P + P P+P G + PT P T + PT G+ P T + T
Sbjct: 3252 TPTTTP-ITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3308
Query: 536 KPEQALEP---------PLVSSTLLRSPGSP-----QETVPEFPCTFLPPTPAPTPPRPP 581
P P+ ++T + +P T P T + PTP PT + P
Sbjct: 3309 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3368
Query: 582 ------------PGPATLAPSRPLLVP--KAERLSP-PAPSGSE 610
P P P P ++P P P+G++
Sbjct: 3369 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3412
Score = 48.5 bits (114), Expect = 3e-05
Identities = 53/224 (23%), Positives = 76/224 (33%), Gaps = 44/224 (19%)
Query: 421 PTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYS 480
PT + P +P TV P P + P P T + +P PT P G
Sbjct: 3383 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-------PTGTQ 3435
Query: 481 EPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATAS-----PPTTAGSNNPCLTQLLTAA 535
P P + P P+P G + PT P T + PT G+ P T + T
Sbjct: 3436 TPTTTP-ITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3492
Query: 536 KPEQALEP---------PLVSSTLLRSPGSP-----QETVPEFPCTFLPPTPAPTPPRPP 581
P P+ ++T + +P T P T + PTP PT + P
Sbjct: 3493 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3552
Query: 582 ------------PGPATLAPSRPLLVP--KAERLSP-PAPSGSE 610
P P P P ++P P P+G++
Sbjct: 3553 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3596
Score = 48.5 bits (114), Expect = 3e-05
Identities = 53/224 (23%), Positives = 76/224 (33%), Gaps = 44/224 (19%)
Query: 421 PTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYS 480
PT + P +P TV P P + P P T + +P PT P G
Sbjct: 3567 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-------PTGTQ 3619
Query: 481 EPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATAS-----PPTTAGSNNPCLTQLLTAA 535
P P + P P+P G + PT P T + PT G+ P T + T
Sbjct: 3620 TPTTTP-ITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3676
Query: 536 KPEQALEP---------PLVSSTLLRSPGSP-----QETVPEFPCTFLPPTPAPTPPRPP 581
P P+ ++T + +P T P T + PTP PT + P
Sbjct: 3677 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3736
Query: 582 ------------PGPATLAPSRPLLVP--KAERLSP-PAPSGSE 610
P P P P ++P P P+G++
Sbjct: 3737 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3780
Score = 48.5 bits (114), Expect = 3e-05
Identities = 53/224 (23%), Positives = 76/224 (33%), Gaps = 44/224 (19%)
Query: 421 PTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYS 480
PT + P +P TV P P + P P T + +P PT P G
Sbjct: 3751 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-------PTGTQ 3803
Query: 481 EPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATAS-----PPTTAGSNNPCLTQLLTAA 535
P P + P P+P G + PT P T + PT G+ P T + T
Sbjct: 3804 TPTTTP-ITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3860
Query: 536 KPEQALEP---------PLVSSTLLRSPGSP-----QETVPEFPCTFLPPTPAPTPPRPP 581
P P+ ++T + +P T P T + PTP PT + P
Sbjct: 3861 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3920
Query: 582 ------------PGPATLAPSRPLLVP--KAERLSP-PAPSGSE 610
P P P P ++P P P+G++
Sbjct: 3921 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3964
Score = 48.5 bits (114), Expect = 3e-05
Identities = 53/224 (23%), Positives = 76/224 (33%), Gaps = 44/224 (19%)
Query: 421 PTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYS 480
PT + P +P TV P P + P P T + +P PT P G
Sbjct: 3935 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-------PTGTQ 3987
Query: 481 EPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATAS-----PPTTAGSNNPCLTQLLTAA 535
P P + P P+P G + PT P T + PT G+ P T + T
Sbjct: 3988 TPTTTP-ITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 4044
Query: 536 KPEQALEP---------PLVSSTLLRSPGSP-----QETVPEFPCTFLPPTPAPTPPRPP 581
P P+ ++T + +P T P T + PTP PT + P
Sbjct: 4045 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 4104
Query: 582 ------------PGPATLAPSRPLLVP--KAERLSP-PAPSGSE 610
P P P P ++P P P+G++
Sbjct: 4105 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 4148
Score = 36.6 bits (83), Expect = 0.099
Identities = 57/242 (23%), Positives = 80/242 (33%), Gaps = 45/242 (18%)
Query: 388 PPPVPPPLLHYPPP----AKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPPA 443
P P P PP A + L PPP P T+ PL T+PPA
Sbjct: 4186 PTPTPTGTQTGPPTHTSTAPIAELTTSNPPP-ESSTPQTSRSTSSPLTESTTLLSTLPPA 4244
Query: 444 PGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQ 503
+ + PP+ + P+ + P + P P G AP+P
Sbjct: 4245 -----IEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTP--- 4296
Query: 504 KASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPE 563
S +A PT + P + + T +P + L+ L + +P E V
Sbjct: 4297 --STVQTTTTSAWTPTPTPLSTPSIIRT-TGLRPYPS--SVLICCVLNDTYYAPGEEVYN 4351
Query: 564 -------------FPCTF------LPPTPAPTPPRPPPGPATLAPSRPLLVPKAERLSPP 604
CT P TP+PTP P +T PS+P P S P
Sbjct: 4352 GTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPT---PSKSTPTPSKPSSTP-----SKP 4403
Query: 605 AP 606
P
Sbjct: 4404 TP 4405
Score = 33.1 bits (74), Expect = 1.1
Identities = 50/215 (23%), Positives = 62/215 (28%), Gaps = 38/215 (17%)
Query: 258 TMTQSGPSPLQL---PPEDAYVGNADMIQPDLTPLQPSLDDFMDISDFFTNSRLPQPPMP 314
T T P+P P + + P TP I+ T + P P
Sbjct: 4134 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 4193
Query: 315 SNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDSSAFLSS 374
P + + + L +S PP SS Q S PL S L S
Sbjct: 4194 QTGPPTHTSTAPIAELTTSNP-----PPESSTP---------QTSRSTSSPLTESTTLLS 4239
Query: 375 DFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPR 434
L P PP P P G PPP +PP
Sbjct: 4240 T-LPPAIEMTSTAPPSTPTA------PTTTSGGHTLSPPPSTTTSPPGT----------- 4281
Query: 435 FPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTP 469
PT G S P P+ T S +P PTP
Sbjct: 4282 ---PTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTP 4313
>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
Length = 2217
Score = 84.7 bits (208), Expect = 3e-16
Identities = 105/347 (30%), Positives = 133/347 (38%), Gaps = 50/347 (14%)
Query: 311 PPMPSNFPEPP-SFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDSS 369
P + +FP+P SF+PV+ PP S+ M +G + P PL
Sbjct: 693 PSLQQHFPDPAMSFAPVL-------------PPPSTPMP--TGPGQPAPPGQQPPPLAQP 737
Query: 370 AFLSSDFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEP 429
L P+P +P PVPP L Y PA G P P AP L Q P
Sbjct: 738 TPLPQVLA----PQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPP 793
Query: 430 LFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPF-PIELLP-LGYSEPAFGPC 487
P P + P G+ LP PT P P P F P +LP L P P
Sbjct: 794 QMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVILPSLAAPLPPASPA 853
Query: 488 FSM-------PRGKPPAPSPRGQKASPPTLAP--ATASPPTTAGSNNPCLTQLLTAAKPE 538
+ P G P A R + P P A A P A S + + QL P
Sbjct: 854 LPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQL-----PG 908
Query: 539 QALEP---PLVSSTLLRSPGSPQETVPEFPCTFLPPTPA----PT-PPRPPPGPATLAPS 590
Q + P P ++ T + P SP TV T PP PA PT PP+P P P
Sbjct: 909 QPVYPAAFPQMAPTDV--PPSPHHTVQNMRAT--PPQPALPPQPTLPPQPVLPPQPTLPP 964
Query: 591 RPLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPIL 637
+P+L P+ R PP P + + +P L VR P QP L
Sbjct: 965 QPVLPPQPTR--PPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHL 1009
Score = 76.3 bits (186), Expect = 1e-13
Identities = 127/465 (27%), Positives = 161/465 (34%), Gaps = 113/465 (24%)
Query: 266 PLQLPPEDAYVGNADMIQPDLTPLQPSLDDFMDISDFFTNSRLPQPPMPSNFPE------ 319
P P E VG+ D + PLQ + + + P PP P PE
Sbjct: 548 PALQPKEQQDVGSPDKARGPPVPLQVQVT-------YHAQAGQPGPPEPEE-PEADQHLL 599
Query: 320 PPSF-----SPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNS-----CPGPLDSS 369
PP+ S DS F SG + S+ + S A S C P+
Sbjct: 600 PPTLPTSATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEG 659
Query: 370 AFLSSDF----------LLPEDPKPRLPPPPVPPPLL-HYPPPAKVPGLEPCPPPPFPPM 418
L P P +P P PP L H+P PA P PPP PM
Sbjct: 660 PVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM--SFAPVLPPPSTPM 717
Query: 419 -------APPTALLQEEPLFSPRFPFPTV-PPAPGVSPLPAPAAFPP--TPQS-VPSPA- 466
APP Q+ P + P P V P P V P P PP P S V +PA
Sbjct: 718 PTGPGQPAPPG---QQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQ 774
Query: 467 --PTPFP-IELLPLGYSEPAFGPCFSMP--------RGKPPA----------PSPRGQKA 505
P P L PL P P +P G PPA P P Q
Sbjct: 775 LKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYF 834
Query: 506 SPPTLAPATASP-----------------PTTAGSNNPCLTQL--LTAAKPEQALEPPLV 546
SP + P+ A+P P A PC T + A P A+ PP V
Sbjct: 835 SPAVILPSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGV 894
Query: 547 SSTLLRS-----PGSP--QETVPEFPCTFLPPTP-------APTPPRPPPGPATLAPSRP 592
++ + S PG P P+ T +PP+P TPP+P P P +P
Sbjct: 895 AALSIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQP 954
Query: 593 LLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPIL 637
+L P + PP P L + P P + PPQP+L
Sbjct: 955 VLPP--QPTLPPQPV-----LPPQPTRPPQPVLPPQPMLPPQPVL 992
Score = 70.9 bits (172), Expect = 5e-12
Identities = 98/384 (25%), Positives = 138/384 (35%), Gaps = 75/384 (19%)
Query: 311 PPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDSSA 370
PP+ P P +P + + P +PP + + + ++L+ PL A
Sbjct: 732 PPLAQPTPLPQVLAP--QPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLA 789
Query: 371 FLSSDFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPC----PPPPFPPMAPPT---- 422
+ P++PP PV PP+ P A + GL P P PP+ PP
Sbjct: 790 QVP----------PQMPPIPVVPPIT---PLAGIDGLPPALPDLPTATVPPVPPPQYFSP 836
Query: 423 -----ALLQEEPLFSPRFPFPTVP-PAPGVSPLPAPAA--FPPTPQSVPSPAPTPFPIEL 474
+L P SP P V P P +PL P P P ++P A P +
Sbjct: 837 AVILPSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAA 896
Query: 475 LPLGYS------EPAFGPCFSM--PRGKPPAP--SPRGQKASPP--------TLAPATAS 516
L + + +P + F P PP+P + + +A+PP TL P
Sbjct: 897 LSIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVL 956
Query: 517 PPTTAGSNNPCLTQLLT-----AAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPP 571
PP P L T P+ L P V P P+ P P P
Sbjct: 957 PPQPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPA 1016
Query: 572 T----------PAP--------TPPRPPPGPATLAPSRP-LLVPKAERLSPPAPSGSERR 612
PAP P P P A L+P P +L+P A L P PS S
Sbjct: 1017 ATPGSQILLGHPAPYAVDVAAQVPTVPVPPAAVLSPPLPEVLLPAAPELLPQFPS-SLAT 1075
Query: 613 LSGDLSSMP-GPGTLSVRVSPPQP 635
+S + S+P TL +PP P
Sbjct: 1076 VSASVQSVPTQTATLLPPANPPLP 1099
Score = 64.7 bits (156), Expect = 3e-10
Identities = 91/326 (27%), Positives = 118/326 (36%), Gaps = 53/326 (16%)
Query: 307 RLPQPP-----MPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNS 361
+LP PP MP P + P L + G SA+ L G A
Sbjct: 860 KLPHPPGAPLAMPCRTIVPNA--PATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAAFP 917
Query: 362 CPGPLD--SSAFLSSDFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMA 419
P D S + + P+P LPP P PP +P PP P
Sbjct: 918 QMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPP-------------QPVLPPQ--PTL 962
Query: 420 PPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPA--PTPFPIELLPL 477
PP +L P PT PP P + P P PP P P PA P P++
Sbjct: 963 PPQPVLP---------PQPTRPPQPVLPPQP---MLPPQPVLPPQPALPVRPEPLQPHLP 1010
Query: 478 GYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKP 537
+ PA P + G PAP A PT+ P A +P L ++L A P
Sbjct: 1011 EQAAPAATPGSQILLGH-PAPYAVDVAAQVPTV------PVPPAAVLSPPLPEVLLPAAP 1063
Query: 538 EQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRP---PPGPATLAPSRPLL 594
E L P SS L + + ++VP T LPP P P P P P P+
Sbjct: 1064 E--LLPQFPSS--LATVSASVQSVPTQTATLLPPANPPLPGGPGIASPCPTVQLTVEPVQ 1119
Query: 595 VPKAERLSPPA-PSGSERRLSGDLSS 619
+A + PP P E D++S
Sbjct: 1120 EEQASQDKPPGLPQSCESYGGSDVTS 1145
Score = 49.7 bits (117), Expect = 1e-05
Identities = 69/235 (29%), Positives = 78/235 (33%), Gaps = 48/235 (20%)
Query: 380 EDPKPRLPPPPVPPPLLHYPPPAKVPG------LEPCPPPPF--------------PPMA 419
E P P P P PL PP A L P F PP A
Sbjct: 1320 EHPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGA 1379
Query: 420 PPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAA-------FPPTPQSVPSPAPTPFPI 472
PP L P P P AP S +P PA+ P TPQ + S T P+
Sbjct: 1380 PPAPLAPSSP---PVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPL 1436
Query: 473 ---ELLPLGYSEPAFG--PCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPC 527
PL G PC P A S R A L P P +G+ P
Sbjct: 1437 AETHEAPLAVQPLVVGLAPCTPAPE----AASTRDASAPREPLPPPAPEPSPHSGTPQPA 1492
Query: 528 LTQ---LLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPR 579
L Q LL AA + L +S L P P TVP P + L PPR
Sbjct: 1493 LGQPAPLLPAAVGAVS----LATSQLPSPPLGP--TVPPQPPSALESDGEGPPPR 1541
Score = 47.8 bits (112), Expect = 4e-05
Identities = 64/245 (26%), Positives = 84/245 (34%), Gaps = 37/245 (15%)
Query: 394 PLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFP-FPTVPPAPGVSPLPAP 452
P+ +P P P P PP A + ++ L S P F + P
Sbjct: 1317 PVAEHPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNP 1376
Query: 453 AAFPPTPQSVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTL-A 511
PP P + SP P+ LP + PA +MP S G +P L +
Sbjct: 1377 PGAPPAPLAPSSP-----PVTALPQDGAAPATS---TMPEPASGTASQAGGPGTPQGLTS 1428
Query: 512 PATASPPTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPP 571
S P P Q L P S+ R +P+E +P PP
Sbjct: 1429 ELETSQPLAETHEAPLAVQPLVVGLAPCTPAPEAAST---RDASAPREPLP-------PP 1478
Query: 572 TPAPTPPRPPPGPATLAPSRPLLVPKAERLSPPAPSGSERRLSGDLSSMP-GPGTLSVRV 630
P P+P P PA P+ PLL PA G+ + L S P GP
Sbjct: 1479 APEPSPHSGTPQPALGQPA-PLL---------PAAVGAVSLATSQLPSPPLGP------T 1522
Query: 631 SPPQP 635
PPQP
Sbjct: 1523 VPPQP 1527
Score = 45.4 bits (106), Expect = 2e-04
Identities = 107/448 (23%), Positives = 149/448 (33%), Gaps = 71/448 (15%)
Query: 262 SGPSPLQLPPEDAYVGNADMIQPDLTPLQPSLDDFMDISDFFTNSRLPQPPMPSNFPEPP 321
S P PL P +A +A + QPS F+ + + PP P P
Sbjct: 1330 SPPLPLSSLPPEASQDSAPYKDQLSSKEQPS---FLASQQLLSQAGPSNPPGAPPAPLAP 1386
Query: 322 SFSPVV----DSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDSSAFLSSDF- 376
S PV D + + PE PAS + G Q S L++S L+
Sbjct: 1387 SSPPVTALPQDGAAPATSTMPE--PASGTASQAGGPGTPQGLTS---ELETSQPLAETHE 1441
Query: 377 -----------LLPEDPKPRL--------PPPPVPPPLLHYPPPAKVPGLEPCPPPPFPP 417
L P P P P P+PPP P + P P P P
Sbjct: 1442 APLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLP 1501
Query: 418 MAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPL 477
A L L SP PTVPP P S L + PP +L L
Sbjct: 1502 AAVGAVSLATSQLPSPPLG-PTVPPQP-PSALESDGEGPPPRVGFVDSTIKSLDEKLRTL 1559
Query: 478 GYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKP 537
Y E P S G P R TL P P + C L P
Sbjct: 1560 LYQEHV--PTSSASAGTPVEVGDRDF-----TLEPLRGDQP----RSEVCGGDLALPPVP 1608
Query: 538 EQAL-------EPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPG------- 583
++A+ +P + S L + G+ E T A + PR G
Sbjct: 1609 KEAVSGRVQLPQPLVEKSELAPTRGAVMEQGTSSSMT------AESSPRSMLGYDRDGRQ 1662
Query: 584 ---PATLAPSRPLLVPKAERLSPPAPSGSERRLSGDLSSMPGP---GTLSVRVSPPQPIL 637
+ + PS P VP R + P+ + +G+ S+ P P GT+ + S PQ +
Sbjct: 1663 VASDSHVVPSVPQDVPAFVRPARVEPTDRDGGEAGESSAEPPPSDMGTVGGQASHPQTLG 1722
Query: 638 SRGRPDSNKTENRRITHISAEQKRRFNI 665
+R K ++ A+ RF++
Sbjct: 1723 ARALGSPRKRPEQQDVSSPAKTVGRFSV 1750
Score = 42.7 bits (99), Expect = 0.001
Identities = 39/142 (27%), Positives = 56/142 (39%), Gaps = 30/142 (21%)
Query: 498 PSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSP 557
P+P ++SPP P ++ PP + + P QL + +P ++S L S P
Sbjct: 1322 PAPEAPESSPPL--PLSSLPPEASQDSAPYKDQLSSKEQPS------FLASQQLLSQAGP 1373
Query: 558 QETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAERLSPPAPSGSERRLSGDL 617
PP PP P LAPS P + + + PA S SG
Sbjct: 1374 SN-----------------PPGAPPAP--LAPSSPPVTALPQDGAAPATSTMPEPASGTA 1414
Query: 618 SSMPGPGT---LSVRVSPPQPI 636
S GPGT L+ + QP+
Sbjct: 1415 SQAGGPGTPQGLTSELETSQPL 1436
Score = 30.0 bits (66), Expect = 9.2
Identities = 26/83 (31%), Positives = 29/83 (34%), Gaps = 11/83 (13%)
Query: 405 PGLE----PCPPPPFPP------MAPPTALLQEEPLFSPRFPFPTVPPA-PGVSPLPAPA 453
PGLE P P PP P + L+ E P P P A PG PA A
Sbjct: 55 PGLEAAEAPGPQPPQPLQRRVLLLCKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADA 114
Query: 454 AFPPTPQSVPSPAPTPFPIELLP 476
P P P P +E P
Sbjct: 115 GPEPVGTQEPGPDPIAAAVETAP 137
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 84.0 bits (206), Expect = 5e-16
Identities = 78/271 (28%), Positives = 101/271 (37%), Gaps = 29/271 (10%)
Query: 380 EDPKPRLPPPPVPPPLLHYPPPAKVPGLEP----CPPPPFPPMAPPTALLQEEPLFSPRF 435
E + +LPPPP+ PP PPP P P CPPPP PP++PP PL
Sbjct: 395 EKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPP-PPVSPP-------PL----- 441
Query: 436 PFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRG-K 494
P P PPA P P T P L P +E + P G
Sbjct: 442 PSPPPPPAQEEQEESPPPVVPATCSRKRGRPP------LTPSQRAERE--AARAGPEGTS 493
Query: 495 PPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEPP--LVSSTLLR 552
PP P+P PP +P A TT N + +A+ + ++ P + +
Sbjct: 494 PPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPK 553
Query: 553 SPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAERLSPPAPSGSERR 612
P V P T PP P P P P A PS P+ +P+ R P+
Sbjct: 554 PPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTS 613
Query: 613 LSGDL-SSMPGPGTLSVRVSPPQPILSRGRP 642
L+ +L P P PP P S RP
Sbjct: 614 LTRELPPPPPAPPPPPAPSPPPAPATSSRRP 644
Score = 62.0 bits (149), Expect = 2e-09
Identities = 67/225 (29%), Positives = 83/225 (36%), Gaps = 46/225 (20%)
Query: 379 PEDPKPRLPP---PPVP--PPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFS- 432
P+ PK + P PP+ PP+ P P P P PP P+ + EP F
Sbjct: 552 PKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRW 611
Query: 433 --------PRFPFPTVPPAPGVSPLPAPAAFPP----TPQSVPS---------------- 464
P P P PPAP P PA ++ P PQ PS
Sbjct: 612 TSLTRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPL 671
Query: 465 -----PAPTPFPIELLPLGYSEPAFGPC--FSMPRGKPPAPSPRGQKASPPTLAPATASP 517
P P P P + P A G S+PR P +P + SP APA ++
Sbjct: 672 GAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHG-APALSNG 730
Query: 518 PTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVP 562
P T L L T P QAL PP L+ P SPQ+ P
Sbjct: 731 PQTQAQLLQPLQALQTQLLP-QALPPP---QPQLQPPPSPQQMPP 771
Score = 59.7 bits (143), Expect = 1e-08
Identities = 63/238 (26%), Positives = 84/238 (35%), Gaps = 29/238 (12%)
Query: 381 DPKPRLPP-----PPVPPPLLHYPPPAKVPGLEPCPP-PPFPPMAP-PTALLQEEPLFSP 433
D P PP P + PP+ PP + P P PP P PP P P + L P
Sbjct: 548 DEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREP 607
Query: 434 RFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYSEPAFGPC------ 487
F + ++ LP P PP P + PSP P P PL P F P
Sbjct: 608 TFRWTSL-----TRELPPPPPAPPPPPA-PSPPPAPATSSRRPLLLRAPQFTPSEAHLKI 661
Query: 488 FSMPRGKPPAPSPRGQKASPPTLAPATASP-PTTAGSNN----PCLTQLLTAAKPEQALE 542
+ PP +P + PP + A P P G N P ++T P +A
Sbjct: 662 YESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTT--PVKAEV 719
Query: 543 PPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAER 600
P + L P + + + P PP P P P P +P E+
Sbjct: 720 SPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPP---PQPQLQPPPSPQQMPPLEK 774
Score = 57.8 bits (138), Expect = 4e-08
Identities = 86/333 (25%), Positives = 113/333 (33%), Gaps = 75/333 (22%)
Query: 382 PKPRLPPPPVP---PPLLHYPPPAKVPGLEPCPPPPF----------PPMAPPTALLQEE 428
P P PPPP P PPL PPP E PPP PP+ P +E
Sbjct: 425 PPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREA 484
Query: 429 PLFSPRF---PFPTVPPAPGVSPLPAPAAFPP-------------------------TPQ 460
P P PT A G P +P P TP+
Sbjct: 485 ARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPR 544
Query: 461 S-VPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAP------A 513
+ P P +E+ P+ P +P+ P PSP P T P +
Sbjct: 545 RFMDEDPPKPPKVEVSPV--LRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRS 602
Query: 514 TASPPTTAGSNNPCLTQLLT----AAKPEQALEPPLVSSTLLRSP---GSPQETVPEFPC 566
PT ++ LT+ L A P A PP +T R P +PQ T E
Sbjct: 603 ILREPTFRWTS---LTRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHL 659
Query: 567 TFL------PPTPAPTPPRPPPGPATLAPS--RPLLVPKAERLSPP-------APSGSER 611
PP AP P P P PA +P+ P V + LS P P +E
Sbjct: 660 KIYESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEV 719
Query: 612 RLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDS 644
G + GP T + + P Q + ++ P +
Sbjct: 720 SPHGAPALSNGPQTQAQLLQPLQALQTQLLPQA 752
Score = 49.3 bits (116), Expect = 1e-05
Identities = 55/191 (28%), Positives = 78/191 (40%), Gaps = 29/191 (15%)
Query: 395 LLHYPPPA-KVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPA 453
++H P P+ + PG E PP + P A + P+ + P + P G +P PAP
Sbjct: 1804 IVHSPAPSSEPPGGED--PPLDTDVLVPGAPERHSPIQNLD---PPLRPDSGSAPPPAPR 1858
Query: 454 AFPPTPQSVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLA-P 512
+F VP+ +P+ P+ +FGP P SP PT+ P
Sbjct: 1859 SFSGARIKVPNYSPSRRPL-------GGVSFGPL-------PSPGSPSSLTHHIPTVGDP 1904
Query: 513 ATASPPTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCT---FL 569
+PP + +P L P + PPL +S LR P P V T
Sbjct: 1905 DFPAPPRRSRRPSP----LAPRPPPSRWASPPLKTSPQLRVP-PPTSVVTALTPTSGELA 1959
Query: 570 PPTPAPTPPRP 580
PP PAP+PP P
Sbjct: 1960 PPGPAPSPPPP 1970
Score = 48.9 bits (115), Expect = 2e-05
Identities = 96/385 (24%), Positives = 126/385 (32%), Gaps = 69/385 (17%)
Query: 276 VGNADMIQPDLTPLQPSLDDFMDISDFFTNSRLPQPPMPSNFPEPPSFSPVVDSLFSSGT 335
V +A + P TP P ++ + D T+S P PPS P V G
Sbjct: 2041 VVSAPGLAPSATPGAPRIEQLDGVDDG-TDSEAEAVQQPRGQGTPPS-GPGVVRAGVLGA 2098
Query: 336 LGPEVPPASSAMTHLSGHSRLQARNSCPGPLDSSAFLSSDFLLP-------EDPKPRLPP 388
G P + + + GP D A + L P P L
Sbjct: 2099 AGDRARPPEDLPSEIVDF----VLKNLGGPGDGGAGPREESLPPAPPLANGSQPSQGLTA 2154
Query: 389 PPVPPPL----LHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAP 444
P P L P +V L P P PP P + + + +F V A
Sbjct: 2155 SPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNKLGQVF--------VKMAG 2206
Query: 445 GVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYSEPAFG--PCFSMPRGKPPAPSP-- 500
P+P P PP P ++ APT + LP G P G P + R PP P P
Sbjct: 2207 EGEPVPPPVKQPPLPPTISPTAPTSW---TLPPG---PLLGVLPVVGVVRPAPPPPPPPL 2260
Query: 501 ----RGQKASPPTLAP--------ATASPPT-------------TAGSNNPCLTQLLTAA 535
ASPP A + SPP A + P + L +
Sbjct: 2261 TLVLSSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDEDGEASEDTPQVPGLGSGG 2320
Query: 536 KPEQALEPPLVSSTL-LRSPGSP---QETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSR 591
++ P V L L PG P + P + L P P PP+ P GP L
Sbjct: 2321 FSRVRMKTPTVRGVLDLDRPGEPAGEESPGPLQERSPLLPLPEDGPPQVPDGPPDL---- 2376
Query: 592 PLLVPKAERLSPPAPSGSERRLSGD 616
LL + S A S E S D
Sbjct: 2377 -LLESQWHHYSGEASSSEEEPPSPD 2400
Score = 45.1 bits (105), Expect = 3e-04
Identities = 53/182 (29%), Positives = 73/182 (40%), Gaps = 15/182 (8%)
Query: 462 VPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTA 521
V SPAP+ P G +P +P G P SP Q PP + ++PP
Sbjct: 1805 VHSPAPSSEPP-----GGEDPPLDTDVLVP-GAPERHSPI-QNLDPPLRPDSGSAPPPAP 1857
Query: 522 GSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPP 581
S + ++ + + L VS L SPGSP P P PA PPR
Sbjct: 1858 RSFSGARIKVPNYSPSRRPLGG--VSFGPLPSPGSPSSLTHHIPTVGDPDFPA--PPRRS 1913
Query: 582 PGPATLAPSRPLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPILSRGR 641
P+ LAP RP P + SPP + + R+ S + S ++PP P S
Sbjct: 1914 RRPSPLAP-RP---PPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPSPPP 1969
Query: 642 PD 643
P+
Sbjct: 1970 PE 1971
Score = 41.6 bits (96), Expect = 0.003
Identities = 29/95 (30%), Positives = 38/95 (40%), Gaps = 20/95 (21%)
Query: 554 PGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAERLSPPAPSGSERRL 613
P + +E P PP P+P PP PPP + +P PL P +SPP
Sbjct: 392 PAAEKEEAKLPPPPLTPPAPSPPPPLPPP---STSPPPPLCPPPPPPVSPP--------- 439
Query: 614 SGDLSSMPGPGTLSVRVSPPQPIL------SRGRP 642
L S P P + P P++ RGRP
Sbjct: 440 --PLPSPPPPPAQEEQEESPPPVVPATCSRKRGRP 472
Score = 39.7 bits (91), Expect = 0.012
Identities = 49/180 (27%), Positives = 63/180 (35%), Gaps = 29/180 (16%)
Query: 305 NSRLPQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPG 364
N + P PS+ P P P +D+ L P P S + +L R + S P
Sbjct: 1801 NQTIVHSPAPSSEP-PGGEDPPLDT----DVLVPGAPERHSPIQNLDPPLRPDS-GSAPP 1854
Query: 365 PLDSSAFLSSDFLLPEDPKPR----------LPPPPVPPPLLHYPPPAKVPGLEPCP--- 411
P S F + +P R LP P P L H+ P P P
Sbjct: 1855 PAPRS-FSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDPDFPAPPRRS 1913
Query: 412 --PPPFPPMAPPTALLQEEPLFSP--RFPFPT-----VPPAPGVSPLPAPAAFPPTPQSV 462
P P P PP+ SP R P PT + P G P PA PP P+ +
Sbjct: 1914 RRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPSPPPPEDL 1973
Score = 36.2 bits (82), Expect = 0.13
Identities = 42/139 (30%), Positives = 54/139 (38%), Gaps = 18/139 (12%)
Query: 318 PEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDSSAFLSS-DF 376
P+ S P FS + +VP S + L G S GPL S SS
Sbjct: 1847 PDSGSAPPPAPRSFSGARI--KVPNYSPSRRPLGGVSF--------GPLPSPGSPSSLTH 1896
Query: 377 LLPEDPKPRLPPPPV----PPPLLHYPPPAK--VPGLEPCPPPPFPP-MAPPTALLQEEP 429
+P P P PP P PL PPP++ P L+ P PP + TAL
Sbjct: 1897 HIPTVGDPDFPAPPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSG 1956
Query: 430 LFSPRFPFPTVPPAPGVSP 448
+P P P+ PP + P
Sbjct: 1957 ELAPPGPAPSPPPPEDLGP 1975
>gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo
sapiens]
Length = 1636
Score = 83.2 bits (204), Expect = 9e-16
Identities = 115/424 (27%), Positives = 149/424 (35%), Gaps = 76/424 (17%)
Query: 262 SGPSPLQLPPEDAYVGNADMIQPDLTPLQPSLDDFMDISDFFTNSRLPQPPMPSNFPEPP 321
+ P PL E++ A +L L P + + D F S P PS FP
Sbjct: 721 TAPKPLLPRREESEAVEAGDPPEELRSLPPDMVAGPRLPDTFLGSATPLHFPPSPFPSST 780
Query: 322 SFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDSSAFLSSDFLLPED 381
P S GP P S T L +Q R PGP +P
Sbjct: 781 GPGPHYLS-------GPLPPGTYSGPTQL-----IQPR--APGP----------HAMPVA 816
Query: 382 PKPRLPPPPVPPPLLHYPPPAKVP---------GLEPCPPPPFPPMAPPTALLQEEPLFS 432
P P L P P P L P + G+ P PP P APP E +
Sbjct: 817 PGPALYPAPAYTPELGLVPRSSPQHGVVSSPYVGVGPAPPVAGLPSAPPPQFSGPELAMA 876
Query: 433 PR----------FPFPT-VPPAPGVSPLPAPAAFP-------PTPQSVPSPAPTPFPIEL 474
R P P+ P P +P P P FP PTP + P+ A P P +
Sbjct: 877 VRPATTTVDSIQAPIPSHTAPRPNPTPAPPPPCFPVPPPQPLPTPYTYPAGAKQPIPAQH 936
Query: 475 -----LPLGYSEPAFGPCFSMPRGKPPAPSPRGQKA---SPPTLAPATASP---PTTAGS 523
+P G+ P GP P+ P P P +A PP P P A
Sbjct: 937 HFSSGIPAGFPAPRIGP---QPQ---PHPQPHPSQAFGPQPPQQPLPLQHPHLFPPQAPG 990
Query: 524 NNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPG 583
P + A +P +PP T L PG Q+ +P P+P P P PP
Sbjct: 991 LLPPQSPYPYAPQPGVLGQPPPPLHTQLY-PGPAQDPLPAHSGALPFPSPGPPQPPHPPL 1049
Query: 584 PATLAPSRPLLVPKAERLSPPAPSGSER-----RLSGDLSSMPGPGTLSVR--VSPPQPI 636
APS + P+A L+ PS + + L + PGPG + R + P P
Sbjct: 1050 AYGPAPSTRPMGPQAAPLTIRGPSSAGQSTPSPHLVPSPAPSPGPGPVPPRPPAAEPPPC 1109
Query: 637 LSRG 640
L RG
Sbjct: 1110 LRRG 1113
Score = 66.6 bits (161), Expect = 9e-11
Identities = 111/422 (26%), Positives = 146/422 (34%), Gaps = 76/422 (18%)
Query: 260 TQSGPSPLQLP---PEDAYVGNADMIQPDLTPLQPSLDDFMDISDFFTNSRLPQPPMPSN 316
+ +GP P L P Y G +IQP +P P P+
Sbjct: 778 SSTGPGPHYLSGPLPPGTYSGPTQLIQPRAPGPHA----------------MPVAPGPAL 821
Query: 317 FPEP---------PSFSP---VVDSLFSSGTLGPEVPPA---SSAMTHLSGHSRLQARNS 361
+P P P SP VV S + +GP P A S+ SG A
Sbjct: 822 YPAPAYTPELGLVPRSSPQHGVVSSPYVG--VGPAPPVAGLPSAPPPQFSGPELAMAVRP 879
Query: 362 CPGPLDSSAFLSSDFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPP 421
+DS +P PR P P PPP P VP +P P P P
Sbjct: 880 ATTTVDSI-----QAPIPSHTAPRPNPTPAPPP-----PCFPVPPPQPLPTPYTYPAGAK 929
Query: 422 TALLQEEPLFS---PRFPFPTVPPAPGVSPLPAPA-AFPPTPQSVPSPAPTP--FPIE-- 473
+ + S FP P + P P P P P+ AF P P P P P FP +
Sbjct: 930 QPIPAQHHFSSGIPAGFPAPRIGPQPQPHPQPHPSQAFGPQPPQQPLPLQHPHLFPPQAP 989
Query: 474 -LLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASP---PTLAPATASPPTTAGSNNPCLT 529
LLP P + P + G+PP P P P A + A P + G P
Sbjct: 990 GLLPPQSPYP-YAPQPGV-LGQPPPPLHTQLYPGPAQDPLPAHSGALPFPSPGPPQPPHP 1047
Query: 530 QLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAP 589
L P P + +R P S ++ P L P+PAP+P P P A
Sbjct: 1048 PLAYGPAPSTRPMGPQAAPLTIRGPSSAGQSTPS---PHLVPSPAPSPGPGPVPPRPPAA 1104
Query: 590 SRPLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDSNKTEN 649
P + + + S E + G S PG G QP+L + D+ E
Sbjct: 1105 EPPPCLRRGAAAADLLSSSPESQHGGTQS--PGGG---------QPLLQPTKVDA--AEG 1151
Query: 650 RR 651
RR
Sbjct: 1152 RR 1153
Score = 40.8 bits (94), Expect = 0.005
Identities = 32/92 (34%), Positives = 40/92 (43%), Gaps = 23/92 (25%)
Query: 387 PPPPVPPPLLHYPPPAKVPGLEPCPPP---PFPPMAPPTALLQEEPLFSPRFPFPTVPPA 443
PP + P+ P PA+ PGL P P P P +PP PL SP +P A
Sbjct: 1509 PPGGLESPVASLPGPAEPPGLPPASLPESTPIPSSSPP-------PLSSP------LPEA 1555
Query: 444 PGVSPLPAPAAFPPTPQSVPSPAPTPFPIELL 475
P P PP P++ PS P +ELL
Sbjct: 1556 ------PQPKEEPPVPEA-PSSGPPSSSLELL 1580
Score = 38.1 bits (87), Expect = 0.034
Identities = 30/86 (34%), Positives = 36/86 (41%), Gaps = 8/86 (9%)
Query: 380 EDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPT 439
E P LP P PP L PPA +P P P PP++ P L E P P P
Sbjct: 1514 ESPVASLPGPAEPPGL----PPASLPESTPIPSSSPPPLSSP---LPEAPQPKEEPPVPE 1566
Query: 440 VPPA-PGVSPLPAPAAFPPTPQSVPS 464
P + P S L A+ P S+ S
Sbjct: 1567 APSSGPPSSSLELLASLTPEAFSLDS 1592
Score = 32.7 bits (73), Expect = 1.4
Identities = 33/120 (27%), Positives = 46/120 (38%), Gaps = 24/120 (20%)
Query: 544 PLVSSTLLRSPGSPQETVP-----EFPCTFLPPTPAPTPPRPP----------PGPATLA 588
PL S+++ + PQ++ + P + + T A RPP PGPA
Sbjct: 1468 PLASASISQKNHLPQDSQDLVLGGDVPISSIQATIAKLSIRPPGGLESPVASLPGPAEPP 1527
Query: 589 PSRPLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDSNKTE 648
P +P+ S P PS S LS L P P + PP P P S+ E
Sbjct: 1528 GLPPASLPE----STPIPSSSPPPLSSPLPEAPQP-----KEEPPVPEAPSSGPPSSSLE 1578
Score = 32.0 bits (71), Expect = 2.4
Identities = 34/119 (28%), Positives = 43/119 (36%), Gaps = 13/119 (10%)
Query: 491 PRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAK----PEQALEPPLV 546
P KP A + QK P S G + P + T AK P LE P+
Sbjct: 1464 PPCKPLASASISQKNHLPQ-----DSQDLVLGGDVPISSIQATIAKLSIRPPGGLESPVA 1518
Query: 547 SST-LLRSPGSPQETVPE---FPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAERL 601
S PG P ++PE P + PP +P P P P P P P + L
Sbjct: 1519 SLPGPAEPPGLPPASLPESTPIPSSSPPPLSSPLPEAPQPKEEPPVPEAPSSGPPSSSL 1577
Score = 31.2 bits (69), Expect = 4.1
Identities = 44/156 (28%), Positives = 64/156 (41%), Gaps = 15/156 (9%)
Query: 212 PPPEQWCKQLFSSVVPVLLGDPEEEPGGRQLLDLNCFLSDISDTLFTMTQSGPSPLQLPP 271
PPP CK L S+ + P++ +L + +S I T+ ++ P L+ P
Sbjct: 1463 PPP---CKPLASASISQKNHLPQDSQD--LVLGGDVPISSIQATIAKLSIRPPGGLESPV 1517
Query: 272 EDAYVGNADMIQPDLTPLQ-PSLDDFMDISDFFTNSRLPQPPMP---SNFPEPPSFSPVV 327
+ G A+ P L P P S +S LP+ P P PE PS P
Sbjct: 1518 A-SLPGPAE--PPGLPPASLPESTPIPSSSPPPLSSPLPEAPQPKEEPPVPEAPSSGPPS 1574
Query: 328 DSLFSSGTLGPEVPPASSAM---THLSGHSRLQARN 360
SL +L PE S++ +S H+ LQA N
Sbjct: 1575 SSLELLASLTPEAFSLDSSLRGKQRMSKHNFLQAHN 1610
Score = 31.2 bits (69), Expect = 4.1
Identities = 28/90 (31%), Positives = 37/90 (41%), Gaps = 16/90 (17%)
Query: 449 LPAPAAFPPTPQSVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPP 508
L +P A P P P P P E P+ S P P S P P AP P K PP
Sbjct: 1513 LESPVASLPGPAEPPGLPPASLP-ESTPIPSSSP---PPLSSPL--PEAPQP---KEEPP 1563
Query: 509 TLAPATASPPTTAGSNNPCLTQLLTAAKPE 538
++ PP+++ +LL + PE
Sbjct: 1564 VPEAPSSGPPSSS-------LELLASLTPE 1586
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 81.6 bits (200), Expect = 3e-15
Identities = 74/256 (28%), Positives = 94/256 (36%), Gaps = 31/256 (12%)
Query: 379 PEDPKPRLPPPPVPPPLLHYPPPAKVPG-LEPCPPPPFPPMAPPTALLQEEPLFSPRFPF 437
P++P P P P P P K P P P P P P +E +P+ P
Sbjct: 314 PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPA 373
Query: 438 PTVP--PAPGVSPLPAPAAFPPTPQSVPSPAPTPF------PIELLPLGYSEPA----FG 485
PT P+P PAP P + PAPT P E P EPA
Sbjct: 374 PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE 433
Query: 486 PCFSMPRG------KPPAPSPRGQKASPPTLAPATASP----PTTAGSNNPCLTQLLTAA 535
P + P+ K PAP+ + A T PA +P PTT P + LT
Sbjct: 434 PAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPT 493
Query: 536 KPEQAL----EPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSR 591
PE+ E P ++ +P +P+E P P P TP P P PA P
Sbjct: 494 TPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKE 553
Query: 592 PLLVPKAERLSPPAPS 607
P E PAP+
Sbjct: 554 PAPTTPKE----PAPT 565
Score = 81.6 bits (200), Expect = 3e-15
Identities = 101/361 (27%), Positives = 131/361 (36%), Gaps = 47/361 (13%)
Query: 309 PQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVP-------PASSAMTHLSGHSRLQARNS 361
P+ P P+ EP +P + + P P P A T + +
Sbjct: 415 PKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEP 474
Query: 362 CPGPLDSSAFLSSDFLLPEDPK------PRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPF 415
P +A + L P P+ P P P P L P P P P
Sbjct: 475 APTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTT 534
Query: 416 PPMAPPTALLQEEPLFSPRFPFPTVP--PAPGVSPLPAPAAFPPT-PQSVPSPAPT---- 468
P A P + P +P+ P PT P PAP AP T P ++ PAPT
Sbjct: 535 PKAAAPNTPKEPAPT-TPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKK 593
Query: 469 PFPIELLPLGYSEPAFGPCF----SMPRGKPPA----PSPRGQKASPPTLAPATASPPTT 520
P P EL P EP C + P+G P P+P K PT TA PTT
Sbjct: 594 PAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTA--PTT 651
Query: 521 AGSNNPCLTQLLTAAKPEQA---LEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTP---A 574
P T A E A + P +++ +P +P+ET P P P TP A
Sbjct: 652 L--KEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPA 709
Query: 575 PTPPRPPPGPATLAPSRPLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQ 634
PT P PP P T S P + P S + +LS+ P P L SP +
Sbjct: 710 PTTPETPP-PTTSEVSTPTTTKE-----PTTIHKSPDESTPELSAEPTPKAL--ENSPKE 761
Query: 635 P 635
P
Sbjct: 762 P 762
Score = 75.5 bits (184), Expect = 2e-13
Identities = 72/284 (25%), Positives = 97/284 (34%), Gaps = 28/284 (9%)
Query: 379 PEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFP 438
P++P P P P + P K P P P P +E +P+ P P
Sbjct: 221 PKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAP 280
Query: 439 TV--PPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYSEPA-FGPCFSMPRGKP 495
T PAP + P P + PAPT P E P EP P P K
Sbjct: 281 TTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTT-PKEPAPTTPKEPTPTTPKEPAPTTKE 339
Query: 496 PA------PSPRGQKASPPTL----APATASPPTTAGSNNPCLT------QLLTAAKPEQ 539
PA P+P K PT AP T P + P T T + P
Sbjct: 340 PAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTT 399
Query: 540 ALEP-PLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPP-------PGPATLAPSR 591
EP P + + +P P T + P P PAPT P+ P P P T
Sbjct: 400 TKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPA 459
Query: 592 PLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQP 635
P K +P P+ + + + + T +++P P
Sbjct: 460 PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTP 503
Score = 74.3 bits (181), Expect = 4e-13
Identities = 65/222 (29%), Positives = 80/222 (36%), Gaps = 14/222 (6%)
Query: 380 EDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPT 439
++P P P P P P K P P P P +E +P+ P PT
Sbjct: 378 KEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPT 437
Query: 440 VP--PAPGVSPLPAPAA-FPPTPQSVPSPAPTPFPIELLPLGYSEPA------FGPCFSM 490
P PAP PAP P P + PAPT P E P E A P +
Sbjct: 438 TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTT-PKEPAPTTPKETAPTTPKKLTP--TT 494
Query: 491 PRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTL 550
P P + +P LAP T PT P T AA P EP ++
Sbjct: 495 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAA-PNTPKEPA-PTTPK 552
Query: 551 LRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRP 592
+P +P+E P P P TP T P PA P +P
Sbjct: 553 EPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKP 594
Score = 69.7 bits (169), Expect = 1e-11
Identities = 86/345 (24%), Positives = 114/345 (33%), Gaps = 37/345 (10%)
Query: 309 PQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQ-----ARNSCP 363
P+ P P+ EP +P + ++ P P + T S + + S P
Sbjct: 353 PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAP 412
Query: 364 GPLDSSAFLSSDFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCP-----PPPFPPM 418
+ ++ P PK P P P PA EP P P P P
Sbjct: 413 TTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPK 472
Query: 419 APPTALLQEEPLFSPRFPFPTVPP--APGVSPLPAPAA---------FPPTPQSVPSPAP 467
P +E +P+ PT P AP PAP PTP + PAP
Sbjct: 473 EPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAP 532
Query: 468 TPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTL----APATASPPTTAGS 523
T P P EPA P P+P K + PT AP T P
Sbjct: 533 TT-PKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTP 591
Query: 524 NNPCLTQLLTAAKPEQA---LEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRP 580
P +L E + P ++ +P +P+E P P P TP T P
Sbjct: 592 KKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTT 651
Query: 581 PPGPATLAPSRPLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGT 625
PA P +P PK L+P G + S P P T
Sbjct: 652 LKEPAPTTPKKP--APK--ELAPTTTKGP----TSTTSDKPAPTT 688
Score = 58.9 bits (141), Expect = 2e-08
Identities = 67/217 (30%), Positives = 78/217 (35%), Gaps = 43/217 (19%)
Query: 380 EDPKPRLPPPPVPPPLLHYPPPAKVPGLEPC--PPPPFPPMAPPTALLQEEPLFSPRFPF 437
++P P P P P L P K P C P P P PT + P +P+ P
Sbjct: 584 KEPAPTTPKKPAPKELA--PTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPT-TPKEPA 640
Query: 438 PTVP----------PAPGVSPLPAPAAFPPTPQSVPS------PAPTPFPIELLPLGYSE 481
PT P PAP PAP PT P+ PAPT P E P E
Sbjct: 641 PTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTT-PKETAPTTPKE 699
Query: 482 PAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQAL 541
PA P P P + S PT T PTT + T L+A +AL
Sbjct: 700 PAPTTPKKPAPTTPETPPPTTSEVSTPT----TTKEPTTIHKSPDESTPELSAEPTPKAL 755
Query: 542 EPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPP 578
E SP+E P P T TPA T P
Sbjct: 756 E------------NSPKE--PGVPTT---KTPAATKP 775
Score = 58.5 bits (140), Expect = 2e-08
Identities = 60/246 (24%), Positives = 90/246 (36%), Gaps = 26/246 (10%)
Query: 400 PPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTP 459
P +KV +P P P +E +P+ P T P P + + + P P
Sbjct: 189 PTSKVLA-KPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEP 247
Query: 460 QSVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPA----PSPRGQKASPPT-LAPAT 514
+ + P E P EPA + P+ P P+P K++P T PA
Sbjct: 248 APTTTKSAPTTPKEPAPTTTKEPA----PTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAP 303
Query: 515 ASP----PTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLP 570
+P PTT P + T P++ P +P P T P+ P P
Sbjct: 304 TTPKKPAPTTPKEPAPTTPKEPTPTTPKE--PAPTTKEPAPTTPKEPAPTAPKKPAPTTP 361
Query: 571 PTPAPTPPRPPPGPATLAPSRPLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTL-SVR 629
PAPT P+ P T PS +P P+ + + + + P P T S
Sbjct: 362 KEPAPTTPKEPAPTTTKEPS---------PTTPKEPAPTTTKSAPTTTKEPAPTTTKSAP 412
Query: 630 VSPPQP 635
+P +P
Sbjct: 413 TTPKEP 418
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 81.6 bits (200), Expect = 3e-15
Identities = 74/256 (28%), Positives = 94/256 (36%), Gaps = 31/256 (12%)
Query: 379 PEDPKPRLPPPPVPPPLLHYPPPAKVPG-LEPCPPPPFPPMAPPTALLQEEPLFSPRFPF 437
P++P P P P P P K P P P P P P +E +P+ P
Sbjct: 355 PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPA 414
Query: 438 PTVP--PAPGVSPLPAPAAFPPTPQSVPSPAPTPF------PIELLPLGYSEPA----FG 485
PT P+P PAP P + PAPT P E P EPA
Sbjct: 415 PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE 474
Query: 486 PCFSMPRG------KPPAPSPRGQKASPPTLAPATASP----PTTAGSNNPCLTQLLTAA 535
P + P+ K PAP+ + A T PA +P PTT P + LT
Sbjct: 475 PAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPT 534
Query: 536 KPEQAL----EPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSR 591
PE+ E P ++ +P +P+E P P P TP P P PA P
Sbjct: 535 TPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKE 594
Query: 592 PLLVPKAERLSPPAPS 607
P E PAP+
Sbjct: 595 PAPTTPKE----PAPT 606
Score = 81.6 bits (200), Expect = 3e-15
Identities = 101/361 (27%), Positives = 131/361 (36%), Gaps = 47/361 (13%)
Query: 309 PQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVP-------PASSAMTHLSGHSRLQARNS 361
P+ P P+ EP +P + + P P P A T + +
Sbjct: 456 PKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEP 515
Query: 362 CPGPLDSSAFLSSDFLLPEDPK------PRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPF 415
P +A + L P P+ P P P P L P P P P
Sbjct: 516 APTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTT 575
Query: 416 PPMAPPTALLQEEPLFSPRFPFPTVP--PAPGVSPLPAPAAFPPT-PQSVPSPAPT---- 468
P A P + P +P+ P PT P PAP AP T P ++ PAPT
Sbjct: 576 PKAAAPNTPKEPAPT-TPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKK 634
Query: 469 PFPIELLPLGYSEPAFGPCF----SMPRGKPPA----PSPRGQKASPPTLAPATASPPTT 520
P P EL P EP C + P+G P P+P K PT TA PTT
Sbjct: 635 PAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTA--PTT 692
Query: 521 AGSNNPCLTQLLTAAKPEQA---LEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTP---A 574
P T A E A + P +++ +P +P+ET P P P TP A
Sbjct: 693 L--KEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPA 750
Query: 575 PTPPRPPPGPATLAPSRPLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQ 634
PT P PP P T S P + P S + +LS+ P P L SP +
Sbjct: 751 PTTPETPP-PTTSEVSTPTTTKE-----PTTIHKSPDESTPELSAEPTPKAL--ENSPKE 802
Query: 635 P 635
P
Sbjct: 803 P 803
Score = 75.5 bits (184), Expect = 2e-13
Identities = 72/284 (25%), Positives = 97/284 (34%), Gaps = 28/284 (9%)
Query: 379 PEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFP 438
P++P P P P + P K P P P P +E +P+ P P
Sbjct: 262 PKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAP 321
Query: 439 TV--PPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYSEPA-FGPCFSMPRGKP 495
T PAP + P P + PAPT P E P EP P P K
Sbjct: 322 TTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTT-PKEPAPTTPKEPTPTTPKEPAPTTKE 380
Query: 496 PA------PSPRGQKASPPTL----APATASPPTTAGSNNPCLT------QLLTAAKPEQ 539
PA P+P K PT AP T P + P T T + P
Sbjct: 381 PAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTT 440
Query: 540 ALEP-PLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPP-------PGPATLAPSR 591
EP P + + +P P T + P P PAPT P+ P P P T
Sbjct: 441 TKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPA 500
Query: 592 PLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQP 635
P K +P P+ + + + + T +++P P
Sbjct: 501 PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTP 544
Score = 74.3 bits (181), Expect = 4e-13
Identities = 65/222 (29%), Positives = 80/222 (36%), Gaps = 14/222 (6%)
Query: 380 EDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPT 439
++P P P P P P K P P P P +E +P+ P PT
Sbjct: 419 KEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPT 478
Query: 440 VP--PAPGVSPLPAPAA-FPPTPQSVPSPAPTPFPIELLPLGYSEPA------FGPCFSM 490
P PAP PAP P P + PAPT P E P E A P +
Sbjct: 479 TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTT-PKEPAPTTPKETAPTTPKKLTP--TT 535
Query: 491 PRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTL 550
P P + +P LAP T PT P T AA P EP ++
Sbjct: 536 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAA-PNTPKEPA-PTTPK 593
Query: 551 LRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRP 592
+P +P+E P P P TP T P PA P +P
Sbjct: 594 EPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKP 635
Score = 69.7 bits (169), Expect = 1e-11
Identities = 86/345 (24%), Positives = 114/345 (33%), Gaps = 37/345 (10%)
Query: 309 PQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQ-----ARNSCP 363
P+ P P+ EP +P + ++ P P + T S + + S P
Sbjct: 394 PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAP 453
Query: 364 GPLDSSAFLSSDFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCP-----PPPFPPM 418
+ ++ P PK P P P PA EP P P P P
Sbjct: 454 TTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPK 513
Query: 419 APPTALLQEEPLFSPRFPFPTVPP--APGVSPLPAPAA---------FPPTPQSVPSPAP 467
P +E +P+ PT P AP PAP PTP + PAP
Sbjct: 514 EPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAP 573
Query: 468 TPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTL----APATASPPTTAGS 523
T P P EPA P P+P K + PT AP T P
Sbjct: 574 TT-PKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTP 632
Query: 524 NNPCLTQLLTAAKPEQA---LEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRP 580
P +L E + P ++ +P +P+E P P P TP T P
Sbjct: 633 KKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTT 692
Query: 581 PPGPATLAPSRPLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGT 625
PA P +P PK L+P G + S P P T
Sbjct: 693 LKEPAPTTPKKP--APK--ELAPTTTKGP----TSTTSDKPAPTT 729
Score = 58.9 bits (141), Expect = 2e-08
Identities = 67/217 (30%), Positives = 78/217 (35%), Gaps = 43/217 (19%)
Query: 380 EDPKPRLPPPPVPPPLLHYPPPAKVPGLEPC--PPPPFPPMAPPTALLQEEPLFSPRFPF 437
++P P P P P L P K P C P P P PT + P +P+ P
Sbjct: 625 KEPAPTTPKKPAPKELA--PTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPT-TPKEPA 681
Query: 438 PTVP----------PAPGVSPLPAPAAFPPTPQSVPS------PAPTPFPIELLPLGYSE 481
PT P PAP PAP PT P+ PAPT P E P E
Sbjct: 682 PTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTT-PKETAPTTPKE 740
Query: 482 PAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQAL 541
PA P P P + S PT T PTT + T L+A +AL
Sbjct: 741 PAPTTPKKPAPTTPETPPPTTSEVSTPT----TTKEPTTIHKSPDESTPELSAEPTPKAL 796
Query: 542 EPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPP 578
E SP+E P P T TPA T P
Sbjct: 797 E------------NSPKE--PGVPTT---KTPAATKP 816
Score = 58.5 bits (140), Expect = 2e-08
Identities = 60/246 (24%), Positives = 90/246 (36%), Gaps = 26/246 (10%)
Query: 400 PPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTP 459
P +KV +P P P +E +P+ P T P P + + + P P
Sbjct: 230 PTSKVLA-KPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEP 288
Query: 460 QSVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPA----PSPRGQKASPPT-LAPAT 514
+ + P E P EPA + P+ P P+P K++P T PA
Sbjct: 289 APTTTKSAPTTPKEPAPTTTKEPA----PTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAP 344
Query: 515 ASP----PTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLP 570
+P PTT P + T P++ P +P P T P+ P P
Sbjct: 345 TTPKKPAPTTPKEPAPTTPKEPTPTTPKE--PAPTTKEPAPTTPKEPAPTAPKKPAPTTP 402
Query: 571 PTPAPTPPRPPPGPATLAPSRPLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTL-SVR 629
PAPT P+ P T PS +P P+ + + + + P P T S
Sbjct: 403 KEPAPTTPKEPAPTTTKEPS---------PTTPKEPAPTTTKSAPTTTKEPAPTTTKSAP 453
Query: 630 VSPPQP 635
+P +P
Sbjct: 454 TTPKEP 459
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 81.6 bits (200), Expect = 3e-15
Identities = 74/256 (28%), Positives = 94/256 (36%), Gaps = 31/256 (12%)
Query: 379 PEDPKPRLPPPPVPPPLLHYPPPAKVPG-LEPCPPPPFPPMAPPTALLQEEPLFSPRFPF 437
P++P P P P P P K P P P P P P +E +P+ P
Sbjct: 407 PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPA 466
Query: 438 PTVP--PAPGVSPLPAPAAFPPTPQSVPSPAPTPF------PIELLPLGYSEPA----FG 485
PT P+P PAP P + PAPT P E P EPA
Sbjct: 467 PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE 526
Query: 486 PCFSMPRG------KPPAPSPRGQKASPPTLAPATASP----PTTAGSNNPCLTQLLTAA 535
P + P+ K PAP+ + A T PA +P PTT P + LT
Sbjct: 527 PAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPT 586
Query: 536 KPEQAL----EPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSR 591
PE+ E P ++ +P +P+E P P P TP P P PA P
Sbjct: 587 TPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKE 646
Query: 592 PLLVPKAERLSPPAPS 607
P E PAP+
Sbjct: 647 PAPTTPKE----PAPT 658
Score = 81.6 bits (200), Expect = 3e-15
Identities = 101/361 (27%), Positives = 131/361 (36%), Gaps = 47/361 (13%)
Query: 309 PQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVP-------PASSAMTHLSGHSRLQARNS 361
P+ P P+ EP +P + + P P P A T + +
Sbjct: 508 PKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEP 567
Query: 362 CPGPLDSSAFLSSDFLLPEDPK------PRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPF 415
P +A + L P P+ P P P P L P P P P
Sbjct: 568 APTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTT 627
Query: 416 PPMAPPTALLQEEPLFSPRFPFPTVP--PAPGVSPLPAPAAFPPT-PQSVPSPAPT---- 468
P A P + P +P+ P PT P PAP AP T P ++ PAPT
Sbjct: 628 PKAAAPNTPKEPAPT-TPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKK 686
Query: 469 PFPIELLPLGYSEPAFGPCF----SMPRGKPPA----PSPRGQKASPPTLAPATASPPTT 520
P P EL P EP C + P+G P P+P K PT TA PTT
Sbjct: 687 PAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTA--PTT 744
Query: 521 AGSNNPCLTQLLTAAKPEQA---LEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTP---A 574
P T A E A + P +++ +P +P+ET P P P TP A
Sbjct: 745 L--KEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPA 802
Query: 575 PTPPRPPPGPATLAPSRPLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQ 634
PT P PP P T S P + P S + +LS+ P P L SP +
Sbjct: 803 PTTPETPP-PTTSEVSTPTTTKE-----PTTIHKSPDESTPELSAEPTPKAL--ENSPKE 854
Query: 635 P 635
P
Sbjct: 855 P 855
Score = 75.5 bits (184), Expect = 2e-13
Identities = 72/284 (25%), Positives = 97/284 (34%), Gaps = 28/284 (9%)
Query: 379 PEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFP 438
P++P P P P + P K P P P P +E +P+ P P
Sbjct: 314 PKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAP 373
Query: 439 TV--PPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYSEPA-FGPCFSMPRGKP 495
T PAP + P P + PAPT P E P EP P P K
Sbjct: 374 TTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTT-PKEPAPTTPKEPTPTTPKEPAPTTKE 432
Query: 496 PA------PSPRGQKASPPTL----APATASPPTTAGSNNPCLT------QLLTAAKPEQ 539
PA P+P K PT AP T P + P T T + P
Sbjct: 433 PAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTT 492
Query: 540 ALEP-PLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPP-------PGPATLAPSR 591
EP P + + +P P T + P P PAPT P+ P P P T
Sbjct: 493 TKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPA 552
Query: 592 PLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQP 635
P K +P P+ + + + + T +++P P
Sbjct: 553 PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTP 596
Score = 74.3 bits (181), Expect = 4e-13
Identities = 65/222 (29%), Positives = 80/222 (36%), Gaps = 14/222 (6%)
Query: 380 EDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPT 439
++P P P P P P K P P P P +E +P+ P PT
Sbjct: 471 KEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPT 530
Query: 440 VP--PAPGVSPLPAPAA-FPPTPQSVPSPAPTPFPIELLPLGYSEPA------FGPCFSM 490
P PAP PAP P P + PAPT P E P E A P +
Sbjct: 531 TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTT-PKEPAPTTPKETAPTTPKKLTP--TT 587
Query: 491 PRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTL 550
P P + +P LAP T PT P T AA P EP ++
Sbjct: 588 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAA-PNTPKEPA-PTTPK 645
Query: 551 LRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRP 592
+P +P+E P P P TP T P PA P +P
Sbjct: 646 EPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKP 687
Score = 69.7 bits (169), Expect = 1e-11
Identities = 86/345 (24%), Positives = 114/345 (33%), Gaps = 37/345 (10%)
Query: 309 PQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQ-----ARNSCP 363
P+ P P+ EP +P + ++ P P + T S + + S P
Sbjct: 446 PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAP 505
Query: 364 GPLDSSAFLSSDFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCP-----PPPFPPM 418
+ ++ P PK P P P PA EP P P P P
Sbjct: 506 TTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPK 565
Query: 419 APPTALLQEEPLFSPRFPFPTVPP--APGVSPLPAPAA---------FPPTPQSVPSPAP 467
P +E +P+ PT P AP PAP PTP + PAP
Sbjct: 566 EPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAP 625
Query: 468 TPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTL----APATASPPTTAGS 523
T P P EPA P P+P K + PT AP T P
Sbjct: 626 TT-PKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTP 684
Query: 524 NNPCLTQLLTAAKPEQA---LEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRP 580
P +L E + P ++ +P +P+E P P P TP T P
Sbjct: 685 KKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTT 744
Query: 581 PPGPATLAPSRPLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGT 625
PA P +P PK L+P G + S P P T
Sbjct: 745 LKEPAPTTPKKP--APK--ELAPTTTKGP----TSTTSDKPAPTT 781
Score = 58.9 bits (141), Expect = 2e-08
Identities = 67/217 (30%), Positives = 78/217 (35%), Gaps = 43/217 (19%)
Query: 380 EDPKPRLPPPPVPPPLLHYPPPAKVPGLEPC--PPPPFPPMAPPTALLQEEPLFSPRFPF 437
++P P P P P L P K P C P P P PT + P +P+ P
Sbjct: 677 KEPAPTTPKKPAPKELA--PTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPT-TPKEPA 733
Query: 438 PTVP----------PAPGVSPLPAPAAFPPTPQSVPS------PAPTPFPIELLPLGYSE 481
PT P PAP PAP PT P+ PAPT P E P E
Sbjct: 734 PTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTT-PKETAPTTPKE 792
Query: 482 PAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQAL 541
PA P P P + S PT T PTT + T L+A +AL
Sbjct: 793 PAPTTPKKPAPTTPETPPPTTSEVSTPT----TTKEPTTIHKSPDESTPELSAEPTPKAL 848
Query: 542 EPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPP 578
E SP+E P P T TPA T P
Sbjct: 849 E------------NSPKE--PGVPTT---KTPAATKP 868
Score = 58.5 bits (140), Expect = 2e-08
Identities = 60/246 (24%), Positives = 90/246 (36%), Gaps = 26/246 (10%)
Query: 400 PPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTP 459
P +KV +P P P +E +P+ P T P P + + + P P
Sbjct: 282 PTSKVLA-KPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEP 340
Query: 460 QSVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPA----PSPRGQKASPPT-LAPAT 514
+ + P E P EPA + P+ P P+P K++P T PA
Sbjct: 341 APTTTKSAPTTPKEPAPTTTKEPA----PTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAP 396
Query: 515 ASP----PTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLP 570
+P PTT P + T P++ P +P P T P+ P P
Sbjct: 397 TTPKKPAPTTPKEPAPTTPKEPTPTTPKE--PAPTTKEPAPTTPKEPAPTAPKKPAPTTP 454
Query: 571 PTPAPTPPRPPPGPATLAPSRPLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTL-SVR 629
PAPT P+ P T PS +P P+ + + + + P P T S
Sbjct: 455 KEPAPTTPKEPAPTTTKEPS---------PTTPKEPAPTTTKSAPTTTKEPAPTTTKSAP 505
Query: 630 VSPPQP 635
+P +P
Sbjct: 506 TTPKEP 511
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 81.6 bits (200), Expect = 3e-15
Identities = 74/256 (28%), Positives = 94/256 (36%), Gaps = 31/256 (12%)
Query: 379 PEDPKPRLPPPPVPPPLLHYPPPAKVPG-LEPCPPPPFPPMAPPTALLQEEPLFSPRFPF 437
P++P P P P P P K P P P P P P +E +P+ P
Sbjct: 448 PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPA 507
Query: 438 PTVP--PAPGVSPLPAPAAFPPTPQSVPSPAPTPF------PIELLPLGYSEPA----FG 485
PT P+P PAP P + PAPT P E P EPA
Sbjct: 508 PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE 567
Query: 486 PCFSMPRG------KPPAPSPRGQKASPPTLAPATASP----PTTAGSNNPCLTQLLTAA 535
P + P+ K PAP+ + A T PA +P PTT P + LT
Sbjct: 568 PAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPT 627
Query: 536 KPEQAL----EPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSR 591
PE+ E P ++ +P +P+E P P P TP P P PA P
Sbjct: 628 TPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKE 687
Query: 592 PLLVPKAERLSPPAPS 607
P E PAP+
Sbjct: 688 PAPTTPKE----PAPT 699
Score = 81.6 bits (200), Expect = 3e-15
Identities = 101/361 (27%), Positives = 131/361 (36%), Gaps = 47/361 (13%)
Query: 309 PQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVP-------PASSAMTHLSGHSRLQARNS 361
P+ P P+ EP +P + + P P P A T + +
Sbjct: 549 PKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEP 608
Query: 362 CPGPLDSSAFLSSDFLLPEDPK------PRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPF 415
P +A + L P P+ P P P P L P P P P
Sbjct: 609 APTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTT 668
Query: 416 PPMAPPTALLQEEPLFSPRFPFPTVP--PAPGVSPLPAPAAFPPT-PQSVPSPAPT---- 468
P A P + P +P+ P PT P PAP AP T P ++ PAPT
Sbjct: 669 PKAAAPNTPKEPAPT-TPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKK 727
Query: 469 PFPIELLPLGYSEPAFGPCF----SMPRGKPPA----PSPRGQKASPPTLAPATASPPTT 520
P P EL P EP C + P+G P P+P K PT TA PTT
Sbjct: 728 PAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTA--PTT 785
Query: 521 AGSNNPCLTQLLTAAKPEQA---LEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTP---A 574
P T A E A + P +++ +P +P+ET P P P TP A
Sbjct: 786 L--KEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPA 843
Query: 575 PTPPRPPPGPATLAPSRPLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQ 634
PT P PP P T S P + P S + +LS+ P P L SP +
Sbjct: 844 PTTPETPP-PTTSEVSTPTTTKE-----PTTIHKSPDESTPELSAEPTPKAL--ENSPKE 895
Query: 635 P 635
P
Sbjct: 896 P 896
Score = 75.5 bits (184), Expect = 2e-13
Identities = 72/284 (25%), Positives = 97/284 (34%), Gaps = 28/284 (9%)
Query: 379 PEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFP 438
P++P P P P + P K P P P P +E +P+ P P
Sbjct: 355 PKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAP 414
Query: 439 TV--PPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYSEPA-FGPCFSMPRGKP 495
T PAP + P P + PAPT P E P EP P P K
Sbjct: 415 TTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTT-PKEPAPTTPKEPTPTTPKEPAPTTKE 473
Query: 496 PA------PSPRGQKASPPTL----APATASPPTTAGSNNPCLT------QLLTAAKPEQ 539
PA P+P K PT AP T P + P T T + P
Sbjct: 474 PAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTT 533
Query: 540 ALEP-PLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPP-------PGPATLAPSR 591
EP P + + +P P T + P P PAPT P+ P P P T
Sbjct: 534 TKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPA 593
Query: 592 PLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQP 635
P K +P P+ + + + + T +++P P
Sbjct: 594 PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTP 637
Score = 74.3 bits (181), Expect = 4e-13
Identities = 65/222 (29%), Positives = 80/222 (36%), Gaps = 14/222 (6%)
Query: 380 EDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPT 439
++P P P P P P K P P P P +E +P+ P PT
Sbjct: 512 KEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPT 571
Query: 440 VP--PAPGVSPLPAPAA-FPPTPQSVPSPAPTPFPIELLPLGYSEPA------FGPCFSM 490
P PAP PAP P P + PAPT P E P E A P +
Sbjct: 572 TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTT-PKEPAPTTPKETAPTTPKKLTP--TT 628
Query: 491 PRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTL 550
P P + +P LAP T PT P T AA P EP ++
Sbjct: 629 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAA-PNTPKEPA-PTTPK 686
Query: 551 LRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRP 592
+P +P+E P P P TP T P PA P +P
Sbjct: 687 EPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKP 728
Score = 69.7 bits (169), Expect = 1e-11
Identities = 86/345 (24%), Positives = 114/345 (33%), Gaps = 37/345 (10%)
Query: 309 PQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQ-----ARNSCP 363
P+ P P+ EP +P + ++ P P + T S + + S P
Sbjct: 487 PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAP 546
Query: 364 GPLDSSAFLSSDFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCP-----PPPFPPM 418
+ ++ P PK P P P PA EP P P P P
Sbjct: 547 TTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPK 606
Query: 419 APPTALLQEEPLFSPRFPFPTVPP--APGVSPLPAPAA---------FPPTPQSVPSPAP 467
P +E +P+ PT P AP PAP PTP + PAP
Sbjct: 607 EPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAP 666
Query: 468 TPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTL----APATASPPTTAGS 523
T P P EPA P P+P K + PT AP T P
Sbjct: 667 TT-PKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTP 725
Query: 524 NNPCLTQLLTAAKPEQA---LEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRP 580
P +L E + P ++ +P +P+E P P P TP T P
Sbjct: 726 KKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTT 785
Query: 581 PPGPATLAPSRPLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGT 625
PA P +P PK L+P G + S P P T
Sbjct: 786 LKEPAPTTPKKP--APK--ELAPTTTKGP----TSTTSDKPAPTT 822
Score = 58.9 bits (141), Expect = 2e-08
Identities = 67/217 (30%), Positives = 78/217 (35%), Gaps = 43/217 (19%)
Query: 380 EDPKPRLPPPPVPPPLLHYPPPAKVPGLEPC--PPPPFPPMAPPTALLQEEPLFSPRFPF 437
++P P P P P L P K P C P P P PT + P +P+ P
Sbjct: 718 KEPAPTTPKKPAPKELA--PTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPT-TPKEPA 774
Query: 438 PTVP----------PAPGVSPLPAPAAFPPTPQSVPS------PAPTPFPIELLPLGYSE 481
PT P PAP PAP PT P+ PAPT P E P E
Sbjct: 775 PTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTT-PKETAPTTPKE 833
Query: 482 PAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQAL 541
PA P P P + S PT T PTT + T L+A +AL
Sbjct: 834 PAPTTPKKPAPTTPETPPPTTSEVSTPT----TTKEPTTIHKSPDESTPELSAEPTPKAL 889
Query: 542 EPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPP 578
E SP+E P P T TPA T P
Sbjct: 890 E------------NSPKE--PGVPTT---KTPAATKP 909
Score = 58.5 bits (140), Expect = 2e-08
Identities = 60/246 (24%), Positives = 90/246 (36%), Gaps = 26/246 (10%)
Query: 400 PPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTP 459
P +KV +P P P +E +P+ P T P P + + + P P
Sbjct: 323 PTSKVLA-KPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEP 381
Query: 460 QSVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPA----PSPRGQKASPPT-LAPAT 514
+ + P E P EPA + P+ P P+P K++P T PA
Sbjct: 382 APTTTKSAPTTPKEPAPTTTKEPA----PTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAP 437
Query: 515 ASP----PTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLP 570
+P PTT P + T P++ P +P P T P+ P P
Sbjct: 438 TTPKKPAPTTPKEPAPTTPKEPTPTTPKE--PAPTTKEPAPTTPKEPAPTAPKKPAPTTP 495
Query: 571 PTPAPTPPRPPPGPATLAPSRPLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTL-SVR 629
PAPT P+ P T PS +P P+ + + + + P P T S
Sbjct: 496 KEPAPTTPKEPAPTTTKEPS---------PTTPKEPAPTTTKSAPTTTKEPAPTTTKSAP 546
Query: 630 VSPPQP 635
+P +P
Sbjct: 547 TTPKEP 552
>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
sapiens]
Length = 483
Score = 81.3 bits (199), Expect = 3e-15
Identities = 98/343 (28%), Positives = 132/343 (38%), Gaps = 58/343 (16%)
Query: 322 SFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNS-CPGPLDSSAFLSSDFLLPE 380
S P + LF+ G P + PA ++G Q S P P + +S + P
Sbjct: 93 STPPTLGDLFAGGF--PVLRPAGQR--DVAGGKTGQGPGSRAPSPRLPNKTISGPLIPPA 148
Query: 381 DPK--------------PRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQ 426
P+ P P P PPP P P P PPPP PP P ++ +
Sbjct: 149 SPRLGNTSEAHGAARTAPPRPNVPAPPP----PTP-------PPPPPPLPPPLPSSSPI- 196
Query: 427 EEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYSEPAFGP 486
+ PL SP P T P V+P P P A PP P P P PTP P+ + S+ A P
Sbjct: 197 KTPLVSPPGPL-TKGNLPVVAP-PVPCAPPPPP---PPPPPTPPPLPPASV-LSDKAVKP 250
Query: 487 CFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEPPLV 546
+ P PP P P PP P + P A+ + A EPP
Sbjct: 251 QLA-PLHLPPIPPP--LPLLPPCGYPGLKAEP---------------ASPAQDAQEPPAP 292
Query: 547 SSTL-LRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAERLSPPA 605
L + SP+ ++P P + + PP PP P+ AP P +PPA
Sbjct: 293 PPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAP--PQKAGAQALPAPPA 350
Query: 606 PSGSERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDSNKTE 648
P GS+ L PG G + P P S S+K++
Sbjct: 351 PPGSQPFLQKKRHGRPGAGGGKLNPPPAPPARSPTTELSSKSQ 393
Score = 72.4 bits (176), Expect = 2e-12
Identities = 95/327 (29%), Positives = 116/327 (35%), Gaps = 69/327 (21%)
Query: 308 LPQPPMPSNFPEP-------PSFSPVVDSLFS------SGTLGPEVPPASSAMTHLSGHS 354
+P PP P+ P P PS SP+ L S G L PP A
Sbjct: 171 VPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPP-----P 225
Query: 355 RLQARNSCPGPLDSSAFLSSDFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLE------ 408
P PL ++ LS + P+ LPP P P PLL PP PGL+
Sbjct: 226 PPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLL---PPCGYPGLKAEPASP 282
Query: 409 -------PCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGV-SPLPAPAAFPPTPQ 460
P PPPP PP A SPR P PP PGV S P PP
Sbjct: 283 AQDAQEPPAPPPPLPPYAS----------CSPRASLP-APPLPGVNSSSETPPPLPPKSP 331
Query: 461 SVPSPAPTPFPIELLPLGYSEPAFGPCFSMPR-GKPPAPSPRGQKASPPTLAPATASPPT 519
S +P P + LP + P P R G+P A G K +PP AP SP T
Sbjct: 332 SFQAP-PQKAGAQALPAPPAPPGSQPFLQKKRHGRPGA---GGGKLNPPP-APPARSPTT 386
Query: 520 TAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPR 579
S +Q TA P Q L + +L + +F F + PP
Sbjct: 387 ELSSK----SQQATAWTPTQQPGGQLRNGSL--------HIIDDFESKFTFHSVEDFPP- 433
Query: 580 PPPGPATLAPSRPLLVPKAERLSPPAP 606
P P + + K R P P
Sbjct: 434 ----PDEYKPCQKIYPSKIPRSRTPGP 456
Score = 70.5 bits (171), Expect = 6e-12
Identities = 78/305 (25%), Positives = 110/305 (36%), Gaps = 61/305 (20%)
Query: 382 PKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQE-EPLFSPRF----- 435
P P PPPP+PPP PPP P P PPP PP++ T+ L+ +P
Sbjct: 2 PVPPPPPPPLPPP----PPPLGAP---PPPPPSAPPVSTDTSSLRRADPKGRSALLADIQ 54
Query: 436 --------------PFPTVPPAPGVSPLPAPAA---FPPTPQSVPSPAPTPFPIELLPLG 478
P + + G + +A TP ++ FP+ L P G
Sbjct: 55 QGTRLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPV-LRPAG 113
Query: 479 YSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLT--------- 529
+ A G P + P+P + S P + PA+ T+ ++ T
Sbjct: 114 QRDVAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPA 173
Query: 530 -QLLTAAKPEQALEPPLVSSTLLRSP----------GSPQETVPEFPCTFLPPTPAPTPP 578
T P L PPL SS+ +++P G+ P PC PP P P PP
Sbjct: 174 PPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCA-PPPPPPPPPP 232
Query: 579 RPPPGPATLAPSRPLLVPKAERLS-PPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPIL 637
PPP P S + P+ L PP P L +P G ++ P P
Sbjct: 233 TPPPLPPASVLSDKAVKPQLAPLHLPPIPP--------PLPLLPPCGYPGLKAEPASPAQ 284
Query: 638 SRGRP 642
P
Sbjct: 285 DAQEP 289
>gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]
Length = 1003
Score = 80.5 bits (197), Expect = 6e-15
Identities = 103/350 (29%), Positives = 129/350 (36%), Gaps = 62/350 (17%)
Query: 312 PMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRL-QARNSCPGPLDSSA 370
P P + P P G+L PE P S A L+G L R + P P S
Sbjct: 140 PGPPSARPPCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAGPGGLFPPRLADPVPSGGS- 198
Query: 371 FLSSDFLLPEDPKPRLPPPPVPPPLLHYPP--------PAKVPGLEPCPPPPFPPMAPPT 422
SS LP P PPP P L+ P + VP PP P +PP+
Sbjct: 199 --SSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPSDLGSPPAPHASSSPPS 256
Query: 423 ALLQEEPLF--SPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYS 480
+ PLF S P +PP+ + P PA+ PP S A P+ L PLG +
Sbjct: 257 ----DPPLFHCSDALTPPPLPPSNNLPAHPGPASQPPV-----SSATMHLPLVLGPLGGA 307
Query: 481 EPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQA 540
GP G PP + A+ P P T G + +A
Sbjct: 308 PTVEGP------GAPPFLASSLLSAAAKAQHPPLPPPSTLQG-------------RRPRA 348
Query: 541 LEPPLVSSTLLRSPGSPQETVPEFPCTFL-------PPTP---APTPPRPPPGPATL-AP 589
P S+ LR P + P P T P TP P P P P P +L P
Sbjct: 349 QAPSASHSSSLR----PSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPEP 404
Query: 590 SRPLLVPKAERLSPPAPSGSER----RLSGDLSSMPGPGTLSVRVSPPQP 635
S+P+L L P P S L G + +P P TLS SPPQP
Sbjct: 405 SQPILPSVLSLLGLPTPGPSHSDGSFNLLGSDAHLPPPPTLS-SGSPPQP 453
Score = 68.9 bits (167), Expect = 2e-11
Identities = 116/433 (26%), Positives = 154/433 (35%), Gaps = 75/433 (17%)
Query: 264 PSPLQLPPEDAYVGNADMIQPDLTPLQ-------PSLDDFMDISDFFTNSRLPQPPMPSN 316
PSP+ P + A P L PL PS + + +S L P+P +
Sbjct: 488 PSPVLQSPSEGLGMGAGPACP-LPPLAGGEAFPFPSPEQGLALSGAGFPGMLGALPLPLS 546
Query: 317 FPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDSSAFLSSDF 376
+PP + SLF T G PP + G A GP S ++S
Sbjct: 547 LGQPPPSPLLNHSLFGVLTGGGGQPPPEPLLPPPGGPGPPLAPGEPEGP---SLLVAS-- 601
Query: 377 LLPEDPKPRLPPPPVPP--------PLLHYPPPA----------------KVPGLEPCPP 412
LLP P LPPP PP PLL P A GL P
Sbjct: 602 LLPPPPSDLLPPPSAPPSNLLASFLPLLALGPTAGDGEGSAEGAGGPSGEPFSGLGDLSP 661
Query: 413 PPFPPM-APPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFP 471
FPP+ APPT + L + + L P+ PP P + +P P P P
Sbjct: 662 LLFPPLSAPPTLIALNSALLA--------------ATLDPPSGTPPQPCVLSAPQPGP-P 706
Query: 472 IELLPLGYSEPAFGPCFSMP--RGKPP-APSPRGQKASPPTLAPATASP---PTTAGSNN 525
+ ++P P G+PP SP + L+ T+SP P+
Sbjct: 707 TSSVTTATTDPGASSLGKAPSNSGRPPQLLSPLLGASLLGDLSSLTSSPGALPSLLQPPG 766
Query: 526 PCLT-QLLTAAKPEQALEPPLVSST-----LLRSPGSPQETVPEFPCTFLPPTPAPTPPR 579
P L+ QL P PPL ++ LL+S P E PE PC LPP +
Sbjct: 767 PLLSGQLGLQLLPGGGAPPPLSEASSPLACLLQSLQIPPEQ-PEAPC--LPPESPASALE 823
Query: 580 PPPGPATLAPSRPLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPILSR 639
P P P L P PP P R SG G G + +P +R
Sbjct: 824 PEPA----RPPLSALAPPHGSPDPPVPELLTGRGSGKRGRRGGGGLRGIN-GEARP--AR 876
Query: 640 GRPDSNKTENRRI 652
GR ++ E R+
Sbjct: 877 GRKPGSRREPGRL 889
Score = 67.4 bits (163), Expect = 5e-11
Identities = 125/491 (25%), Positives = 169/491 (34%), Gaps = 83/491 (16%)
Query: 193 RKPSREDDLLAPKQAEGRWPPPEQWCKQLFSSVV------PVLLGDPEEEPGGRQLLDLN 246
R P R G PP Q F ++ P L DP G
Sbjct: 146 RPPCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAGPGGLFPPRLADPVPSGGS------- 198
Query: 247 CFLSDISDTLFTMTQSGPSPLQLPPEDAYVGNADMIQPDLTPLQPSLDDFMDISDFFTNS 306
S F + PSP PP P ++ PS + + S
Sbjct: 199 ------SSPRFLPRGNAPSPAPPPP------------PAISLNAPSYNWGAALRSSLVPS 240
Query: 307 RLPQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCP--- 363
L PP P PPS P+ S P +PP+++ H S+ ++
Sbjct: 241 DLGSPPAPHASSSPPSDPPLFHC--SDALTPPPLPPSNNLPAHPGPASQPPVSSATMHLP 298
Query: 364 ---GPLDSSA---------FLSSDFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCP 411
GPL + FL+S LL K + PP P P L P A+ P
Sbjct: 299 LVLGPLGGAPTVEGPGAPPFLASS-LLSAAAKAQHPPLPPPSTLQGRRPRAQAPSASHSS 357
Query: 412 ---PPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFP-PTPQSVPSPA- 466
P P PPT E P+ P + P AP +P+P P + P P+ +PS
Sbjct: 358 SLRPSQRRPRRPPTVFRLLEGR-GPQTPRRSRPRAP--APVPQPFSLPEPSQPILPSVLS 414
Query: 467 ----PTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAG 522
PTP P +S+ +F S PP P SPP P P+ G
Sbjct: 415 LLGLPTPGP------SHSDGSFNLLGSDAHLPPP---PTLSSGSPPQ--PRHPIQPSLPG 463
Query: 523 SNNPCLTQLLTAAKPEQALEPPLVSSTLLRSP--GSPQETVPEFPCTFLPPTPAPTPPRP 580
+ + L+ + A P A + P+V S +L+SP G P P L A P P
Sbjct: 464 TTSGSLSSVPGAPAPPAASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPSP 523
Query: 581 PPGPATLAPSRP-----LLVPKAERLSPPAPSGSERRLSGDLS---SMPGPGTLSVRVSP 632
G A P L +P + PP+P L G L+ P P L
Sbjct: 524 EQGLALSGAGFPGMLGALPLPLSLGQPPPSPL-LNHSLFGVLTGGGGQPPPEPLLPPPGG 582
Query: 633 PQPILSRGRPD 643
P P L+ G P+
Sbjct: 583 PGPPLAPGEPE 593
>gi|62000702 diacylglycerol kinase kappa [Homo sapiens]
Length = 1271
Score = 80.1 bits (196), Expect = 8e-15
Identities = 70/213 (32%), Positives = 80/213 (37%), Gaps = 40/213 (18%)
Query: 399 PPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAA---- 454
P + P P PPPP+PP PP A PL S P P P P ++P P P A
Sbjct: 14 PQDGEQPAESPEPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEPCPELAPGPCPEATSES 73
Query: 455 -----FPPTPQSVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKP---PAPSPRGQKAS 506
PTP+ PA P P EPA P P +P PAP P + A
Sbjct: 74 ATELYTEPTPEPATEPASEPAP---------EPATEPA-PEPATEPAPEPAPEPATESAP 123
Query: 507 PPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEF-- 564
PT PA S P A +L PE A EP T L +P E PEF
Sbjct: 124 EPTPEPALESVPEPA-------PELTPEVAPELAPEPTPEPVTEL-APEFCPEAAPEFRP 175
Query: 565 ---PCTFLPPTPA-----PTPPRPPPGPATLAP 589
PC P T P P P P+ P
Sbjct: 176 SPAPCLLQCPVDTRERGLKTSPSPSPSPSPRTP 208
Score = 71.2 bits (173), Expect = 4e-12
Identities = 70/213 (32%), Positives = 86/213 (40%), Gaps = 39/213 (18%)
Query: 379 PEDPKPRLPPPPVP-----PPLLHYPPPAKVPGLEPCP---PPPFPPMAPPTALLQEEPL 430
PE P P PPPP P PPLL P +P EPCP P P P +A L
Sbjct: 24 PEPPPPWPPPPPPPAPPPAPPLLSEASPEPIP--EPCPELAPGPCPEATSESA----TEL 77
Query: 431 FSPRFPFPTVPPAPGVSPLPAPAAFP-PTPQSVPSPAPTPFP-IELLPLGYSEPAFGPCF 488
++ P P PA P P PA P P P + P+P P P P E P EPA
Sbjct: 78 YTEPTPEPATEPAS--EPAPEPATEPAPEPATEPAPEPAPEPATESAPEPTPEPAL---- 131
Query: 489 SMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALE-PPLVS 547
P P+P P LAP P +T+L PE A E P +
Sbjct: 132 ----ESVPEPAPELTPEVAPELAPEPTPEP---------VTELAPEFCPEAAPEFRPSPA 178
Query: 548 STLLRSPGSPQETVPEFPCTFLPPTPAPTPPRP 580
LL+ P +E + T P+P+P+P P
Sbjct: 179 PCLLQCPVDTRERGLK---TSPSPSPSPSPRTP 208
Score = 64.7 bits (156), Expect = 3e-10
Identities = 63/177 (35%), Positives = 74/177 (41%), Gaps = 17/177 (9%)
Query: 439 TVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPAP 498
T PP G P +P PP P P PAP P P LL EP PC + G P P
Sbjct: 11 TAPPQDGEQPAESPEPPPPWPPPPPPPAPPPAP-PLLSEASPEPIPEPCPELAPG--PCP 67
Query: 499 SPRGQKA----SPPTLAPAT--ASPPTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLR 552
+ A + PT PAT AS P + P + T PE A E P S
Sbjct: 68 EATSESATELYTEPTPEPATEPASEPAPEPATEPA-PEPATEPAPEPAPE-PATESAPEP 125
Query: 553 SPGSPQETVPEFPCTFLPPTPAP-TPPRPPPGPAT-LAPSRPLLVPKAERLSPPAPS 607
+P E+VPE P L P AP P P P P T LAP P+A P+P+
Sbjct: 126 TPEPALESVPE-PAPELTPEVAPELAPEPTPEPVTELAPE---FCPEAAPEFRPSPA 178
Score = 58.5 bits (140), Expect = 2e-08
Identities = 64/212 (30%), Positives = 78/212 (36%), Gaps = 30/212 (14%)
Query: 309 PQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDS 368
P+PP P P PP P L S + P P A CP
Sbjct: 24 PEPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEPCPEL-----------APGPCPEATSE 72
Query: 369 SAFLSSDFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEE 428
SA ++ P+P P P P PA P EP P P P E
Sbjct: 73 SA---TELYTEPTPEPATEPASEPA-----PEPATEPAPEPATEPAPEPAPEPATESAPE 124
Query: 429 PLFSPRFPFPTVP-PAPGVSPLPAPAAFP-PTPQSVPSPAPTPFPIELLPLGYSEPAFGP 486
P +P +VP PAP ++P AP P PTP+ V AP P E P PA P
Sbjct: 125 P--TPEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCP-EAAPEFRPSPA--P 179
Query: 487 CFSMPRGKPPAPSPRGQKASP-PTLAPATASP 517
C P RG K SP P+ +P+ +P
Sbjct: 180 CLLQ---CPVDTRERGLKTSPSPSPSPSPRTP 208
Score = 33.1 bits (74), Expect = 1.1
Identities = 22/68 (32%), Positives = 32/68 (47%), Gaps = 5/68 (7%)
Query: 570 PPTPAPTPPRPPPGPATLAPSRPLLVPK-AERLSP-PAPSGSERRLSGDLSSMPGPGTLS 627
PP P P P PPP P L+ + P +P+ L+P P P + + +L + P P +
Sbjct: 31 PPPPPP--PAPPPAPPLLSEASPEPIPEPCPELAPGPCPEATSESAT-ELYTEPTPEPAT 87
Query: 628 VRVSPPQP 635
S P P
Sbjct: 88 EPASEPAP 95
>gi|11386183 WAS protein family, member 2 [Homo sapiens]
Length = 498
Score = 79.7 bits (195), Expect = 1e-14
Identities = 70/250 (28%), Positives = 89/250 (35%), Gaps = 40/250 (16%)
Query: 266 PLQLPPEDAYVGNADMIQPDLTPLQPSLDDFMDISDFFTNSRLPQPPMPSNFPEPPSFSP 325
P L ++ +G + + P P D S F+ LP PP ++P
Sbjct: 225 PPTLVYQNGSIGCVENVDASSYPPPPQSDSASSPSPSFSEDNLPPPPAEFSYP------- 277
Query: 326 VVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDSSAFLSSDFLLPEDPKPR 385
VD+ SG GP+ S++ S S PGP A P
Sbjct: 278 -VDNQRGSGLAGPK----RSSVVSPSHPPPAPPLGSPPGPKPGFA-------------PP 319
Query: 386 LPPPPVPPPLLHYPPPAKVPGLEP--CPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPPA 443
PPP PPP++ PPP G PPPP PP PP P F P PP
Sbjct: 320 PAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPP----------HPDFAAPPPPPP 369
Query: 444 PGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQ 503
P + P PP P S P+ P P P G P F P PP
Sbjct: 370 PPAADYPT---LPPPPLSQPTGGAPPPPPPPPPPGPPPPPFTGADGQPAIPPPLSDTTKP 426
Query: 504 KASPPTLAPA 513
K+S P ++ A
Sbjct: 427 KSSLPAVSDA 436
Score = 75.1 bits (183), Expect = 3e-13
Identities = 73/258 (28%), Positives = 87/258 (33%), Gaps = 82/258 (31%)
Query: 360 NSCPGPLDSSAFLSSDFLLPEDPKPRLPPPPVPPPLLHYPP----------PAKVPGLEP 409
+S P P S + S ED LPPPP YP P + + P
Sbjct: 244 SSYPPPPQSDSASSPSPSFSED---NLPPPPAE---FSYPVDNQRGSGLAGPKRSSVVSP 297
Query: 410 CPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTP 469
PPP PP+ P P PG +P PAP PP +P P P
Sbjct: 298 SHPPPAPPLGSPPG------------------PKPGFAPPPAPPPPPPPMIGIPPPPP-- 337
Query: 470 FPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLT 529
P+G+ P G PP PSP P AP PP A + P L
Sbjct: 338 ------PVGFGSP----------GTPPPPSPPSFPPHPDFAAPPPPPPPPAA--DYPTLP 379
Query: 530 QLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAP 589
PPL T G+P PP P P PP PPP P T A
Sbjct: 380 P------------PPLSQPT----GGAP------------PPPPPPPPPGPPPPPFTGAD 411
Query: 590 SRPLLVPKAERLSPPAPS 607
+P + P + P S
Sbjct: 412 GQPAIPPPLSDTTKPKSS 429
Score = 45.4 bits (106), Expect = 2e-04
Identities = 68/261 (26%), Positives = 83/261 (31%), Gaps = 75/261 (28%)
Query: 381 DPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPTV 440
+ K +L PP L++ + +E +PP PP + P SP F +
Sbjct: 214 ESKEKLGTSGYPPTLVYQN--GSIGCVENVDASSYPP--PPQSDSASSP--SPSFSEDNL 267
Query: 441 PPAPGVSPLPAP-----AAFPPTPQSVPSPA-PTPFPIELLPLGYSEPAFGPCFSMPRGK 494
PP P P P SV SP+ P P P PLG S P P F+ P
Sbjct: 268 PPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPAP----PLG-SPPGPKPGFAPPPAP 322
Query: 495 PPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSP 554
PP P P PP PP GS P
Sbjct: 323 PPPPPPMIGIPPPP--------PPVGFGS------------------------------P 344
Query: 555 GSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAERLSPPAPSGSERRLS 614
G+P P P+PP PP P AP P P A+ + P P LS
Sbjct: 345 GTP---------------PPPSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPP-----LS 384
Query: 615 GDLSSMPGPGTLSVRVSPPQP 635
P P PP P
Sbjct: 385 QPTGGAPPPPPPPPPPGPPPP 405
>gi|7706501 WW domain binding protein 11 [Homo sapiens]
Length = 641
Score = 79.3 bits (194), Expect = 1e-14
Identities = 75/241 (31%), Positives = 89/241 (36%), Gaps = 15/241 (6%)
Query: 374 SDFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSP 433
SD + + PP VPP + PP P L P P PP P PPT L P +P
Sbjct: 380 SDGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAP 439
Query: 434 RFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRG 493
PF P PG+ P P PP P P P P P LP G P GP +P
Sbjct: 440 --PFLRPPGMPGLRG-PLPRLLPPGPPPGRPPGPPPGPPPGLPPG--PPPRGPPPRLPPP 494
Query: 494 KPPA-PSPRGQKASPPTLAPATASPP---TTAGSNNPCL----TQLLTAAKPEQALEPPL 545
PP P PR PP + P +PP A NP + L+ K + +
Sbjct: 495 APPGIPPPRPGMMRPPLVPPLGPAPPGLFPPAPLPNPGVLSAPPNLIQRPKADDTSAATI 554
Query: 546 VSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAERLSPPA 605
PQ T P+ T PT R AT AP R A L+ A
Sbjct: 555 EKKATATISAKPQITNPKAEITRFVPTALRV--RRENKGATAAPQRKSEDDSAVPLAKAA 612
Query: 606 P 606
P
Sbjct: 613 P 613
Score = 60.8 bits (146), Expect = 5e-09
Identities = 51/166 (30%), Positives = 59/166 (35%), Gaps = 34/166 (20%)
Query: 306 SRLPQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGP 365
S++ PPMP P P +P + L P PP + G L+ GP
Sbjct: 400 SQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGMPGLR------GP 453
Query: 366 LDSSAFLSSDFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALL 425
L PRL PP PP PPP PGL P PPP PP
Sbjct: 454 L-----------------PRLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPP-------- 488
Query: 426 QEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFP 471
P P P PP PG+ P P P + PAP P P
Sbjct: 489 ---PRLPPPAPPGIPPPRPGMMRPPLVPPLGPAPPGLFPPAPLPNP 531
Score = 53.9 bits (128), Expect = 6e-07
Identities = 50/149 (33%), Positives = 56/149 (37%), Gaps = 12/149 (8%)
Query: 495 PPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSP 554
PP P Q +PP P PP P L P A PP LR P
Sbjct: 393 PPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGA--PPF-----LRPP 445
Query: 555 GSPQETVPEFPCTFLPPTPAP-TPPRPPPGPATLAPSRPLLVPKAERLSPPAPSGSERRL 613
G P P P LPP P P PP PPPGP P P RL PPAP G
Sbjct: 446 GMPGLRGP-LP-RLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGIPPPR 503
Query: 614 SGDLSS--MPGPGTLSVRVSPPQPILSRG 640
G + +P G + PP P+ + G
Sbjct: 504 PGMMRPPLVPPLGPAPPGLFPPAPLPNPG 532
Score = 33.5 bits (75), Expect = 0.84
Identities = 24/72 (33%), Positives = 30/72 (41%), Gaps = 17/72 (23%)
Query: 365 PLDSSAFLSSDFLLPEDPKPRLPPPPV--------PP-------PLLHYPPPAKVPGLEP 409
PL S+ L+ + P P PP + PP PLL + P PG +P
Sbjct: 140 PLPDMPHAPSNILIQDIPLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKP 199
Query: 410 CPPPPFPPMAPP 421
PPP PP PP
Sbjct: 200 PGPPPGPP--PP 209
>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
sapiens]
Length = 1560
Score = 78.6 bits (192), Expect = 2e-14
Identities = 119/428 (27%), Positives = 153/428 (35%), Gaps = 74/428 (17%)
Query: 260 TQSGPSP-LQLPPEDAYVGNADMIQPDLTPLQPSLDDFM--DISDFFTNSRLPQPPMPSN 316
T PSP L PE +G P Q SL F+ + S ++ P +P++
Sbjct: 662 TTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPAS 721
Query: 317 F---PEPPSFSPVVDSLFSSGT-LGPEVPPASSAMTHLSGHSRLQARNSCPGPLDSSAF- 371
PP+ P + + G LGP+ P S A + A PGP S +
Sbjct: 722 VIVSAPPPAQDPAPATPVAKGAGLGPQAPD-SQASPAPAPQIPAAAPLKGPGPSSSPSLP 780
Query: 372 ----LSSDFLLPEDPKPRLPP--PPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALL 425
L LP P P PP PP P + PP P L PCPPP PP P ++
Sbjct: 781 HQAPLGDSPHLPS-PHPTRPPSRPPSRPQSVSRPPSE--PPLHPCPPPQAPPTLPGIFVI 837
Query: 426 QEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYSEPAFG 485
Q + P P PAP P P P PQS P P P L P S
Sbjct: 838 QNQLGVPP----PASNPAP---TAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVAS 890
Query: 486 PCFSMPRGKPPAPS-----------PRGQKASPPT--LAPATASPPTTAGSNNPCLTQLL 532
+ R P PS P PPT L P A+PP +T
Sbjct: 891 SSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPF 950
Query: 533 TA-AKPEQALE--PPLVSSTLLR-----SPGSPQETVPEFPCTF---------LPPTPAP 575
A +P+ LE + S +L+ +P +PQ + P T P+ P
Sbjct: 951 PALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTP 1010
Query: 576 TPPRPPPGPATLAPS--RPLL---------------VPKAERLSPPAPSGSERRLSGDLS 618
T P P PA +A + PLL V KA P PSG + LS
Sbjct: 1011 TAPSHAPAPAPMAATGLPPLLPAENKAFASNLPTLNVAKAASSGPGKPSGLQ--YESKLS 1068
Query: 619 SMPGPGTL 626
+ P TL
Sbjct: 1069 GLKKPPTL 1076
Score = 67.4 bits (163), Expect = 5e-11
Identities = 77/288 (26%), Positives = 98/288 (34%), Gaps = 71/288 (24%)
Query: 388 PPPVPPPLLHYPP----PAKVPGLEPCPPPPF---PPMAPPTALLQEEPL---------- 430
PP P P PP P PGL P PP A PTA+L ++ L
Sbjct: 647 PPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQ 706
Query: 431 --FSPRFPFPTVP-------PAPGVSPLPA-PAAF-----PPTPQSVPSPAPTPFPIELL 475
S P +VP P P P PA P A P P S SPAP P
Sbjct: 707 QPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAA 766
Query: 476 PLGYSEPAFGPCFSMPRGKP-------PAPSPRGQKASPPTLAPATASPPTTAGSNNPCL 528
PL P+ P S+P P P+P P + PP+ + + PP+
Sbjct: 767 PLKGPGPSSSP--SLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPS--------- 815
Query: 529 TQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPP-PGPATL 587
EPPL P P + P P F+ PP P P
Sbjct: 816 -------------EPPL-------HPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAP 855
Query: 588 APSRPLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQP 635
P +P L P+++ P P S S++ S R+ P P
Sbjct: 856 GPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTP 903
Score = 66.6 bits (161), Expect = 9e-11
Identities = 86/304 (28%), Positives = 108/304 (35%), Gaps = 77/304 (25%)
Query: 377 LLPEDPKPRLPPP-PVPPPLLHYPPPAKVPGLEPCPPPPFPPM----------------- 418
+L P P+ PP P PL P A+ P P P PP
Sbjct: 618 VLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKI 677
Query: 419 -------APPTALLQEEPL------------FSPRFPFPTVP-------PAPGVSPLPA- 451
A PTA+L ++ L S P +VP P P P PA
Sbjct: 678 VLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPAT 737
Query: 452 PAA-----FPPTPQSVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKP-------PAPS 499
P A P P S SPAP P PL P+ P S+P P P+P
Sbjct: 738 PVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSP--SLPHQAPLGDSPHLPSPH 795
Query: 500 PRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQE 559
P + PP+ P + S P + +PC P QA PP + + Q
Sbjct: 796 PTRPPSRPPS-RPQSVSRPPSEPPLHPC--------PPPQA--PPTLPGIFVI---QNQL 841
Query: 560 TVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAERLSPPAPSGSERRLSGDLSS 619
VP P P AP PP+PP P + P PL P A L P + S + S S
Sbjct: 842 GVP--PPASNPAPTAPGPPQPPLRPQSQPPEGPL--PPAPHLPPSSTSSAVASSSETSSR 897
Query: 620 MPGP 623
+P P
Sbjct: 898 LPAP 901
Score = 52.4 bits (124), Expect = 2e-06
Identities = 77/279 (27%), Positives = 99/279 (35%), Gaps = 31/279 (11%)
Query: 388 PPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVS 447
P V P L P + G P P P T +LQ L P
Sbjct: 546 PIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQP 605
Query: 448 PLPAPAAFPPTPQSVPSPAPTPFPIEL--LPLGYSEP-AFGP-------CFSMPRGKPPA 497
PA A P PAP P LPLG +P A P + P+ P
Sbjct: 606 ATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQ 665
Query: 498 PSPRGQKASPPTLA---PATASPPTTAGSNNPCLTQLLTAAKPEQAL--EPPLVS---ST 549
PSP G +SP + P +A+P TA L L + +Q L E P +S S
Sbjct: 666 PSP-GLASSPEKIVLGQPPSATP--TAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASV 722
Query: 550 LLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAERLSPPAPSGS 609
++ +P Q+ P P A P+ P A+ AP+ +P A L P PS S
Sbjct: 723 IVSAPPPAQDPAPATPVA----KGAGLGPQAPDSQASPAPAPQ--IPAAAPLKGPGPSSS 776
Query: 610 ----ERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDS 644
+ GD +P P PP S RP S
Sbjct: 777 PSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPS 815
Score = 43.1 bits (100), Expect = 0.001
Identities = 59/226 (26%), Positives = 77/226 (34%), Gaps = 36/226 (15%)
Query: 381 DPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSP-RFPFPT 439
DP + PPPP KV P PPPP PP + P +P R P T
Sbjct: 1328 DPVHQPPPPPA---------TLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGT 1378
Query: 440 VPPAPGVSPLPAPAAF------PPTPQSVP-------SPAPTPFPIELLPLGYSEPAFGP 486
P P LP + P P+ P SPAP P ++ G
Sbjct: 1379 APHCP---RLPLRKTYRENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAV 1435
Query: 487 ----CFSMPRGKPPAP-SPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQ-- 539
M +G PP P + Q P P S +P + Q ++ Q
Sbjct: 1436 EDELYQRMLKGPPPEPAASAAQGTGDPDWEAPGLPPAKRRKSESPDVDQASFSSDSPQDD 1495
Query: 540 ALEPPLVSS--TLLRSPGSPQET-VPEFPCTFLPPTPAPTPPRPPP 582
L L S+ ++L +P T P +P TPA PP P
Sbjct: 1496 TLTEHLQSAIDSILNLQQAPGRTPAPSYPHAASAGTPASPPPLHRP 1541
Score = 34.7 bits (78), Expect = 0.38
Identities = 112/472 (23%), Positives = 149/472 (31%), Gaps = 106/472 (22%)
Query: 226 VPVLLGDPEEEPGGRQLLDLNCFLSDISDTLFTMTQSGPSPLQLPPEDAYVGNADMIQPD 285
+P L G P PGG T G +P+Q+ + N
Sbjct: 211 IPGLQGLPNGSPGGA-----------------TAATLGLAPIQVVGQPVMALN------- 246
Query: 286 LTPLQPSLDDFMDISDFFTNSRLPQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASS 345
TP L + +S + ++ P P+ SP L L V +
Sbjct: 247 -TPTSQLLAKQVPVSGYLASAAGPSEPVTL---ASAGVSPQGAGLVIQKNLSAAVATTLN 302
Query: 346 AMTHLSGHSRLQARNSCPG--PLDSSAFLSSDFLLPEDPKPRLPPPPVPPPLLHYPPPAK 403
+ G A P PL + L S L+P P + P P+ P
Sbjct: 303 GNSVFGGAGAASAPTGTPSGQPLAVAPGLGSSPLVPA---PNVILHRTPTPIQPKPAGVL 359
Query: 404 VPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPG---------------VSP 448
P L P PF P A T +Q EP P P AP +S
Sbjct: 360 PPKLYQLTPKPFAP-AGATLTIQGEP-----GALPQQPKAPQNLTFMAAGKAGQNVVLSG 413
Query: 449 LPAPA---------------AFPPTPQSVPSPAPTPFPIELLPLGYS--EPAFGPC---- 487
PAPA A PP P P P + LL G S PA
Sbjct: 414 FPAPALQANVFKQPPATTTGAAPPQP---PGALSKPMSVHLLNQGSSIVIPAQHMLPGQN 470
Query: 488 -FSMPRGKPPAPSPRGQKASPPTLAP--ATASPPTTAGS--NNPCLT--------QLLTA 534
F +P G P P+ A P + A+ P T G NP LT L
Sbjct: 471 QFLLP-GAPAVQLPQQLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPV 529
Query: 535 AKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRP-PPGPA-------- 585
P + S G P + + P + L PT +P P GPA
Sbjct: 530 LAPHSGAHSAHILSAAPIQVGQP--ALFQMPVS-LAAGSLPTQSQPAPAGPAATTVLQGV 586
Query: 586 TLAPSRPLLVPKAERLSPPA-PSGSERRLSGDLSSMPGPGTLSVRVSPPQPI 636
TL PS ++ + L PA P+ + + L+ P P VS P P+
Sbjct: 587 TLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAP-QAPPAVSTPLPL 637
Score = 30.0 bits (66), Expect = 9.2
Identities = 41/160 (25%), Positives = 58/160 (36%), Gaps = 17/160 (10%)
Query: 462 VPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPR---------GQKASPPTLAP 512
V S PI G+ P GP S G P P G P++
Sbjct: 1202 VSSSRSLGLPIAASSEGHRLPGHGPLSSSAPGASTQPPPHLPTKLVIRHGGAGGSPSVTW 1261
Query: 513 ATASPPTTAGSNNPCLTQLLTAAK--PEQALEPPLVSSTLLRSP-GSPQETVPEFPCTFL 569
A AS ++ S++ L A + P + P + + RS G + E + +
Sbjct: 1262 ARASSSLSSSSSSSSAASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQEAGLSKV 1321
Query: 570 PPTPAPTPP-RPPPGPATLAPSRPLLVPKAERLSPPAPSG 608
A P +PPP PATL + P P PP P+G
Sbjct: 1322 VHNTALDPVHQPPPPPATLKVAEPPPRPP----PPPPPTG 1357
>gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]
Length = 1682
Score = 77.8 bits (190), Expect = 4e-14
Identities = 92/331 (27%), Positives = 118/331 (35%), Gaps = 64/331 (19%)
Query: 299 ISDFFTNSRLPQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQA 358
+ + F + P P P P F S FS GT PP T S +S +
Sbjct: 501 LEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGS 560
Query: 359 RNSCP-GPLDSSAFLSSDFLLPE-DPKPRLPPP---PVPPPLLHYPPPAKVPGLEPCPPP 413
+S P GP+ +F +L DP PR P P P PPL+ P + L P PP
Sbjct: 561 HSSSPAGPV---SFPPPPYLARSIDPLPRPPSPAQNPQDPPLV----PLTL-ALPPAPPS 612
Query: 414 PFPPMAPPTALLQEEPLFSPRFPFPTVP---PAPGVSPL-PAPAAFPPTPQSVPSPAPTP 469
+ E P PR FP P P P PL AP PP +P+ P
Sbjct: 613 SCHQNTSGSFRRPESP--RPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGVGELPARGPRL 670
Query: 470 FPIELLPL--GYSEPAFGPCFSMPRG---------------------------KPPAPSP 500
F PL + EPA +P G +PP P
Sbjct: 671 FDFPPTPLEDQFEEPA--EFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEP 728
Query: 501 RGQKASP-PTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQE 559
SP PT T + P A + T TA + E+ PP + P
Sbjct: 729 FASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPAL---------PPPP 779
Query: 560 TVPEFPCTFLPPTPAPTPPRPPPGPATLAPS 590
+ +FP PP+ PP PPP PA+L S
Sbjct: 780 PLAKFP----PPSQPQPPPPPPPSPASLLKS 806
Score = 64.3 bits (155), Expect = 4e-10
Identities = 112/450 (24%), Positives = 140/450 (31%), Gaps = 149/450 (33%)
Query: 251 DISDTLFTMTQSGPSPLQ--LPPEDAY---------VGNADMIQPDLTPLQPSLDDFMDI 299
+I + LF T+ P P LP + + VG D P TP P+
Sbjct: 499 EILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPP-TPPTPTTSS---- 553
Query: 300 SDFFTNSRLPQPPMPSNFPEPPSFSPVVDSLFS--SGTLGPEVPPASSAMTHLSGHSRLQ 357
S+ + S P P +FP PP + +D L S P+ PP L
Sbjct: 554 SNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLALP------ 607
Query: 358 ARNSCPGPLDSS-AFLSSDFLLPEDPKPRLP--------PPPVPPPLLHYPPP------- 401
P P S S F PE P+PR+ P P P PL P P
Sbjct: 608 -----PAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGVGE 662
Query: 402 --AKVPGLEPCPPPPF-------------------------------------------- 415
A+ P L PP P
Sbjct: 663 LPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQ 722
Query: 416 PPMAPPTALLQEEPLFSPRFPFPTVP-----------------------PAPGVSPLPAP 452
PP+ P A LQ P + P T P P P + P P
Sbjct: 723 PPLKEPFASLQS-PFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPPL 781
Query: 453 AAFPPTPQSVPSPAPTPFPIELLP--------LGYSEPAFGPCFSMPRGKPPAPSPRGQK 504
A FPP Q P P P P P LL Y G S P P P Q
Sbjct: 782 AKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVS----TRPGPLPTTQ- 836
Query: 505 ASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSP---QETV 561
SP + ATA PPT+A A + + +P SS+ + G P +
Sbjct: 837 YSPGPPSGATALPPTSA------------APSAQGSPQPSASSSSQFSTSGGPWARERRA 884
Query: 562 PEFPCTFLPPTPAPTPPRPPPGPATLAPSR 591
E P P P P PP P +L P+R
Sbjct: 885 GE------EPVPGPMTPTQPPPPLSLPPAR 908
Score = 57.4 bits (137), Expect = 5e-08
Identities = 85/312 (27%), Positives = 104/312 (33%), Gaps = 75/312 (24%)
Query: 311 PPMPSNFPEPPSFSPVVDSLFSSGT------LGPEVPPASSAMT---HLSGHSRL-QARN 360
P PS P P + S SS T P +P A T +S H RL + +
Sbjct: 384 PYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVSHHGRLGPSAH 443
Query: 361 SCPGPLDSSAFLSSDFLLPEDPKPRLPPPPVPPPLLHYPPP---AKVPGLEPC------- 410
S P + + LP P P PPPP P LL PPP K P
Sbjct: 444 SSRKPFLGAPAATPHLSLP--PGPSSPPPPPCPRLLRPPPPPAWLKGPACRAAREDGEIL 501
Query: 411 ---------PPPPFPPMAPPTALLQEEPLFSPRFPFPT----VPPAPGVSPLPAPAAFPP 457
PP P PP P P + RF T PP P P P
Sbjct: 502 EELFFGTEGPPRPAPPPLPHREGFLGPP--ASRFSVGTQDSHTPPTP-----PTPTTSSS 554
Query: 458 TPQSVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASP 517
S + P+ P Y + P +PR PA +P+ P TLA A P
Sbjct: 555 NSNSGSHSSSPAGPVSFPPPPYLARSIDP---LPRPPSPAQNPQDPPLVPLTLALPPA-P 610
Query: 518 PTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTP 577
P++ N +S R P SP+ P P TP
Sbjct: 611 PSSCHQN----------------------TSGSFRRPESPR------PRVSFPKTP-EVG 641
Query: 578 PRPPPGPATLAP 589
P PPPGP + AP
Sbjct: 642 PGPPPGPLSKAP 653
Score = 55.5 bits (132), Expect = 2e-07
Identities = 107/426 (25%), Positives = 131/426 (30%), Gaps = 117/426 (27%)
Query: 308 LPQPPMPSNFPEPPSFSPVVDSLFSS-----------GTL-----GPE----VPPASSAM 347
LP PP+P P PP P + L +S TL GPE PP
Sbjct: 246 LPPPPLPPPPPPPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQ 305
Query: 348 THLSGHSRLQARNSCPGPLDSSAFLSSDFLLPEDPKPRLPP--PPVPPPLLHYPPPAKVP 405
H H P P + A+ + P RL P PP P P PP A+
Sbjct: 306 RHSLPH---------PYPYPAPAYTA------HPPGHRLVPAAPPGPGP---RPPGAESH 347
Query: 406 GLEPCPPPPFPPM----------------APPTALLQEEPLFSPRFPFPTV--------- 440
G P PP + A TA + P P P T
Sbjct: 348 GCLPATRPPGSDLRESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSN 407
Query: 441 ---------PPAPGVSPLPAPA-------AFPPTPQSVPSP---APTPFPIELLPLGYSE 481
P PG PA P+ S P AP P LP G S
Sbjct: 408 TGLRGVEPNPGIPGADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSS 467
Query: 482 PAFGPCFSMPRGKPP-----APSPRGQKASPPTL-----------APATASPPTTAGSNN 525
P PC + R PP P+ R + L PA P G
Sbjct: 468 PPPPPCPRLLRPPPPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLG 527
Query: 526 PCLTQLLTAAKPEQA-LEPPLVSSTLLRSPGSPQETVPEFPCTFLPP-------TPAPTP 577
P ++ + PP +++ S + P P +F PP P P P
Sbjct: 528 PPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRP 587
Query: 578 PRPPPGPATLAPSRPLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVS-PPQPI 636
P P P P LVP L P PS + SG S P + RVS P P
Sbjct: 588 PSPAQN-----PQDPPLVPLTLALPPAPPSSCHQNTSG---SFRRPESPRPRVSFPKTPE 639
Query: 637 LSRGRP 642
+ G P
Sbjct: 640 VGPGPP 645
Score = 53.5 bits (127), Expect = 8e-07
Identities = 59/204 (28%), Positives = 76/204 (37%), Gaps = 40/204 (19%)
Query: 382 PKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQE--EPLFSPRF---- 435
P P LPPPP PL +PPP+ +P PPPP PP P +LL+ L ++
Sbjct: 771 PPPALPPPP---PLAKFPPPS-----QPQPPPPPPP--SPASLLKSLASVLEGQKYCYRG 820
Query: 436 ----------PFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYSEPAFG 485
P PT +PG P A PPT + PS +P P +S G
Sbjct: 821 TGAAVSTRPGPLPTTQYSPG--PPSGATALPPT-SAAPSAQGSPQPSASSSSQFSTSG-G 876
Query: 486 PCFSMPR-GKPPAPSPRGQKASPP--TLAPATASPPTTAGSNNPCLT-------QLLTAA 535
P R G+ P P P PP +L PA + + C T A
Sbjct: 877 PWARERRAGEEPVPGPMTPTQPPPPLSLPPARSESEVLEEISRACETLVERVGRSATDPA 936
Query: 536 KPEQALEPPLVSSTLLRSPGSPQE 559
P EP + L P +E
Sbjct: 937 DPVDTAEPADSGTERLLPPAQAKE 960
Score = 52.8 bits (125), Expect = 1e-06
Identities = 74/265 (27%), Positives = 90/265 (33%), Gaps = 34/265 (12%)
Query: 384 PRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMA-PPTALLQEEPLFSPRFPFPTVPP 442
P PPP PPP PPP P PPPP P +A P L + L+S P
Sbjct: 245 PLPPPPLPPPP----PPP-------PPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPE 293
Query: 443 APGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRG 502
G AP S+P P P P P + A P + PP P PR
Sbjct: 294 RKG----SAPPERQEQRHSLPHPYPYPAP--------AYTAHPPGHRLVPAAPPGPGPRP 341
Query: 503 QKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVP 562
A PAT P + + +++ ++ P A V R PG P T
Sbjct: 342 PGAESHGCLPATRPPGSDLRESRVQRSRMDSSVSP--AATTACVPYAPSRPPGLPGTTTS 399
Query: 563 EFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAERLSPPAPSGSERRLSG-----DL 617
+ P P A + L V RL P A S + L L
Sbjct: 400 SSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHL 459
Query: 618 SSMPGPGTLSVRVSPPQPILSRGRP 642
S PGP S PP P L R P
Sbjct: 460 SLPPGP---SSPPPPPCPRLLRPPP 481
Score = 30.0 bits (66), Expect = 9.2
Identities = 25/66 (37%), Positives = 30/66 (45%), Gaps = 12/66 (18%)
Query: 570 PPTPAPTPPRPPPGPATLAPSRPLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTLSVR 629
PP PAP PP G ++ PS+P P A P P R L G L S+ G +R
Sbjct: 54 PPLPAPLPPSH--GSSSGHPSKPYYAPGA-----PTP----RPLHGKLESLHGCVQALLR 102
Query: 630 VSPPQP 635
P QP
Sbjct: 103 -EPAQP 107
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 77.8 bits (190), Expect = 4e-14
Identities = 117/481 (24%), Positives = 163/481 (33%), Gaps = 92/481 (19%)
Query: 189 KKRLRKPSREDDLLAPKQAEGRWPPPEQWCKQLFS-------------SVVPVLLGDPEE 235
+K+ K R++++ K+++ + PPP++ K S S P EE
Sbjct: 545 EKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEE 604
Query: 236 EP-------GGRQL-LDLNCFLSDISDTLFTMTQSGPSPLQLPPEDAYVGNADMIQPDLT 287
+ RQL LD+N + + + QS L+ N D I+ D
Sbjct: 605 DKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKN-------SNPDEIEIDFE 657
Query: 288 PLQPSLDDFMD--ISDFFTNSRLPQPPMPS---------NFPEPPSFSPVVDSLFSSGTL 336
L+PS ++ ++ R PQ F S S S S
Sbjct: 658 TLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDS 717
Query: 337 GPEVPPASSAMTHLSG------HSRLQARNSCPGPLDSSAFLSSDFLLPEDPKPRLPPPP 390
E+ P S H H Q P P+ P P+ PPPP
Sbjct: 718 ETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQP----------PPPPQQPPPP 767
Query: 391 VPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPP----APGV 446
PP PPP P P P +PP + + P+ P+ P P +
Sbjct: 768 PPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPI 827
Query: 447 SPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKAS 506
LP P P PQ P TP + + S PA ++P+ +P PS R
Sbjct: 828 LHLPQPELPPHLPQ--PPEHSTPPHLNQHAV-VSPPALHN--ALPQ-QPSRPSNRAAALP 881
Query: 507 PPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALE------PPLVSSTL------LRSP 554
P P SP T P L Q A P+ LE PPL S + L+
Sbjct: 882 PKPARPPAVSPALT---QTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKV 938
Query: 555 GSPQETVPEFPCTFLPPTPAPTPPRP---------PPGPATLAPSRPLLVPKAERLSPPA 605
P +P PP P P PP P PP P P +P P+ + PP
Sbjct: 939 QPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPP---PPPQPQPPPQQQHQPPPR 995
Query: 606 P 606
P
Sbjct: 996 P 996
Score = 70.5 bits (171), Expect = 6e-12
Identities = 95/377 (25%), Positives = 135/377 (35%), Gaps = 74/377 (19%)
Query: 264 PSPLQLPPEDAYVGNAD---MIQPDLTPLQPSLD-DFMDISDFFTNS--RLPQPPMPSNF 317
P P +P + A + I + L+P L D FT LPQP +P +
Sbjct: 780 PPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHL 839
Query: 318 PEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDSSAFLSSDFL 377
P+PP S PP HL+ H+ + + + L S+
Sbjct: 840 PQPPEHS---------------TPP------HLNQHA-VVSPPALHNALPQQPSRPSNRA 877
Query: 378 LPEDPKPRLPPPPVP----PPLLHYPPPAKVPG-LEPCPPPPFPPMAPPTALLQEEPLFS 432
PKP PP P PLL PP A+ P L PP PP+ L + L
Sbjct: 878 AALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQK 937
Query: 433 PRFPFPTVP-------PAPGVSPLPAPAAF---------PPTPQSVPSP----APTPFPI 472
+ P P +P P P + P P P+ PP PQ P P P P P+
Sbjct: 938 VQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPV 997
Query: 473 ELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLL 532
L P+ +S P P+G+ P P GQ+ P P A P ++
Sbjct: 998 HLQPMQFSTHIQQP--PPPQGQQPPHPPPGQQPPP----PQPAKPQQVIQHHH------- 1044
Query: 533 TAAKPEQALEPPLVSSTLLRSPG-----SPQETVPEFPCTFLPPTPAPTPPRPPPGPATL 587
P P + L +P SPQ + + PP P + A++
Sbjct: 1045 ---SPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASV 1101
Query: 588 APSRPLLVPKAERLSPP 604
+PL+V K E++ P
Sbjct: 1102 VQPQPLVVVKEEKIHSP 1118
Score = 61.2 bits (147), Expect = 4e-09
Identities = 66/253 (26%), Positives = 86/253 (33%), Gaps = 26/253 (10%)
Query: 397 HYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVP--PAPGVSPLPAPAA 454
H+ + P P PPP P PP Q++ P P P++P AP + P P
Sbjct: 742 HHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFI 801
Query: 455 FPPTPQSVPSPAPTPFPIELLPLG-YSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPA 513
P P + F P+G +++P P P P P P A
Sbjct: 802 ATQVPVLEPQLPGSVFD----PIGHFTQPILH--LPQPELPPHLPQPPEHSTPPHLNQHA 855
Query: 514 TASPPT--TAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPP 571
SPP A P AA P + PP VS L ++P PQ + + P L
Sbjct: 856 VVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLED 915
Query: 572 TPAPTPPRPP-------PGPATLAPSRPLL--VPKAERLSPPAPSGSERRLSGDLSSMPG 622
P PP + P PLL V + PP P + L P
Sbjct: 916 EEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPP 975
Query: 623 PGTLSVRVSPPQP 635
P PPQP
Sbjct: 976 P------PPPPQP 982
Score = 52.8 bits (125), Expect = 1e-06
Identities = 90/396 (22%), Positives = 132/396 (33%), Gaps = 93/396 (23%)
Query: 264 PSPLQLPPEDAYVGNADMIQPDLTPLQPSLDDFMDISDFFTNSRLPQPPM-PSN----FP 318
P P +LPP + QP P L+ +S ++ LPQ P PSN P
Sbjct: 831 PQP-ELPPH--------LPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALP 881
Query: 319 EPPSFSPVVDSLFSSGTLGPEVP-------------PASSAMTHLSGHSRLQ-------- 357
P+ P V + L P+ P P + +T + LQ
Sbjct: 882 PKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPP 941
Query: 358 --------ARNSCPGPLDSSAFLSSDFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEP 409
++ P PL S L + P P PP P PPP + PP + L+P
Sbjct: 942 TPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQP 1001
Query: 410 C--------PPPP---FPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPT 458
PPPP PP PP Q+ P P P + +P
Sbjct: 1002 MQFSTHIQQPPPPQGQQPPHPPPG---QQPP------PPQPAKPQQVIQHHHSPRHHKSD 1052
Query: 459 PQSVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPP 518
P S P P+ + P S+ PP + + +K L A+ P
Sbjct: 1053 PYSTGHLREAPSPLMI-----HSPQMSQFQSLTHQSPPQQNVQPKKQE---LRAASVVQP 1104
Query: 519 TTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSP--QETVPEFPCTFLPPTPAPT 576
Q L K E+ + P++ S P SP + P+ P + P P
Sbjct: 1105 -----------QPLVVVK-EEKIHSPIIRS----EPFSPSLRPEPPKHPESIKAPVHLPQ 1148
Query: 577 PPRPPPGPATLAPSRPLLVPKAERLSPPAPSGSERR 612
P P + RP++ P + PP +++
Sbjct: 1149 RPEMKP----VDVGRPVIRPPEQNAPPPGAPDKDKQ 1180
Score = 47.0 bits (110), Expect = 7e-05
Identities = 48/173 (27%), Positives = 66/173 (38%), Gaps = 40/173 (23%)
Query: 399 PPPAKVPGLEPCPPP------PFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAP 452
PP + P +P PPP PFP + P L+ + P+ + VPP P +P P P
Sbjct: 205 PPQTQTP--QPNPPPVQATPHPFPAVTPD--LIVQTPVMT------VVPPQPLQTPPPVP 254
Query: 453 AAFPPTPQSVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAP 512
PQ P PAP P P++ S P + P + +G K T P
Sbjct: 255 ------PQPQPPPAPAPQPVQ------SHPPI-----IAATPQPVKTKKGVKRKADTTTP 297
Query: 513 ATASPPTTAGS--NNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPE 563
T P S P T+L + + ++PP P S Q PE
Sbjct: 298 TTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKD-----VPDSQQHPAPE 345
Score = 41.2 bits (95), Expect = 0.004
Identities = 48/179 (26%), Positives = 69/179 (38%), Gaps = 31/179 (17%)
Query: 444 PGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQ 503
PGVS +P TP +P P P P++ P + PA P + P+
Sbjct: 191 PGVSTVPNTTQ-ASTPPQTQTPQPNPPPVQATP--HPFPAVTPDLIVQTPVMTVVPPQPL 247
Query: 504 KASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPE 563
+ +PP + P PP A +P Q+ PP++++T P ++ V
Sbjct: 248 Q-TPPPVPPQPQPPPA-------------PAPQPVQS-HPPIIAAT--PQPVKTKKGVKR 290
Query: 564 FPCTFLPPT--PAPTPPRPPPGPATL------APSRPLLVPK---AERLSPPAPSGSER 611
T P T P PP PP P T SRP+ PK + PAP S +
Sbjct: 291 KADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSK 349
Score = 38.1 bits (87), Expect = 0.034
Identities = 35/136 (25%), Positives = 48/136 (35%), Gaps = 33/136 (24%)
Query: 380 EDPKPRLPP--------PPVPP------PLLHYPPPAKVPGLEPCPPPPFPPMAPPTALL 425
+ P+P PP P V P P++ PP + P PP P PP AP +
Sbjct: 209 QTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPV 268
Query: 426 QEEPLFSPRFPFP------------TVPPAPGVSPLPAPAAFPPTPQSV------PSPAP 467
Q P P P T P + P+ P + PP P++ S P
Sbjct: 269 QSHPPIIAATPQPVKTKKGVKRKADTTTPTT-IDPIHEPPSLPPEPKTTKLGQRRESSRP 327
Query: 468 TPFPIELLPLGYSEPA 483
P + +P PA
Sbjct: 328 VKPPKKDVPDSQQHPA 343
Score = 36.6 bits (83), Expect = 0.099
Identities = 29/92 (31%), Positives = 42/92 (45%), Gaps = 15/92 (16%)
Query: 501 RGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQET 560
RG+K + T P ++ P T ++ P TQ P+ PP V +T P +
Sbjct: 181 RGRKETG-TAKPGVSTVPNTTQASTPPQTQT-----PQP--NPPPVQATPHPFPAVTPDL 232
Query: 561 VPEFPC-TFLPPTPAPTPP------RPPPGPA 585
+ + P T +PP P TPP +PPP PA
Sbjct: 233 IVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPA 264
Score = 34.7 bits (78), Expect = 0.38
Identities = 31/94 (32%), Positives = 36/94 (38%), Gaps = 21/94 (22%)
Query: 382 PKPRLPPPPVPPPL--LHYPPPAKVPGLEPCPP-----PPFPPMAPPTALLQEEPLFSPR 434
P P P PPP+ +P PA P L P PP P PP P
Sbjct: 205 PPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPP-----------PV 253
Query: 435 FPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPT 468
P P PPAP +P P + PP + P P T
Sbjct: 254 PPQPQPPPAP--APQPV-QSHPPIIAATPQPVKT 284
Score = 33.9 bits (76), Expect = 0.64
Identities = 23/80 (28%), Positives = 32/80 (40%), Gaps = 12/80 (15%)
Query: 554 PGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAERLSPPAPSGSERRL 613
PG Q+ + PAP P +PPP P P P P+ ++ PP P
Sbjct: 731 PGREQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPP---PQQQQQPPPPPPP----- 782
Query: 614 SGDLSSMPGPGTLSVRVSPP 633
SMP +++ SPP
Sbjct: 783 ----PSMPQQAAPAMKSSPP 798
Score = 33.5 bits (75), Expect = 0.84
Identities = 25/103 (24%), Positives = 38/103 (36%), Gaps = 8/103 (7%)
Query: 492 RGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLL 551
RG+ + + ++ P A+ P T NP Q P A+ P L+ T +
Sbjct: 181 RGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQ--ATPHPFPAVTPDLIVQTPV 238
Query: 552 RSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLL 594
+ VP P PP P P P P P + P++
Sbjct: 239 MT------VVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPII 275
Score = 33.5 bits (75), Expect = 0.84
Identities = 25/97 (25%), Positives = 34/97 (35%), Gaps = 12/97 (12%)
Query: 379 PEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFP 438
P P+P+ PP P P P+ +PP A T +P+ P P
Sbjct: 252 PVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEP----P 307
Query: 439 TVPPAPGVSPL--------PAPAAFPPTPQSVPSPAP 467
++PP P + L P P S PAP
Sbjct: 308 SLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAP 344
>gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]
Length = 1970
Score = 77.4 bits (189), Expect = 5e-14
Identities = 109/403 (27%), Positives = 148/403 (36%), Gaps = 40/403 (9%)
Query: 265 SPLQLPPEDAYV----GNADMIQPDLTPLQPSLDDFMDISDFFTNSRLPQPPMPSNFPEP 320
SP P AY G P +P PS + S P PS P
Sbjct: 1590 SPSYSPTSPAYEPRSPGGYTPQSPSYSPTSPSYSPTSP--SYSPTSPNYSPTSPSYSPTS 1647
Query: 321 PSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDSSAFLSSDFLLPE 380
PS+SP S + P P S + + S + P S +S P
Sbjct: 1648 PSYSPTSPSYSPTS---PSYSPTSPSYSPTS--PSYSPTSPSYSPTSPSYSPTSPSYSPT 1702
Query: 381 DPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPP--PFPPMAPPTALLQEEPLFSPRFPFP 438
P P P Y P + P P P P P PT+ P +SP P
Sbjct: 1703 SPSYSPTSPSYSPTSPSYSPTS--PSYSPTSPSYSPTSPSYSPTS-----PNYSPTSPNY 1755
Query: 439 TVPPAPGVSPLPAPAAFPPTPQSVP-SPAPTPFPIELLPLGYSEPAFGPCFS--MPRGKP 495
T P +P SP +P+ P +P P SP +P P S P +S PR P
Sbjct: 1756 T-PTSPSYSPT-SPSYSPTSPNYTPTSPNYSPTSPSYSPTSPSYSPTSPSYSPSSPRYTP 1813
Query: 496 PAPS--PRGQKASP--PTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLL 551
+P+ P SP P+ +P + T+ S +P + T P+ + P S T
Sbjct: 1814 QSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPEY-TPTSPKYSPTSPKYSPTSP 1872
Query: 552 R-SPGSP--QETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAERLSPPAPSG 608
+ SP SP T P++ T PT +PT P P +P+ P P + + SP +P+
Sbjct: 1873 KYSPTSPTYSPTTPKYSPT--SPTYSPTSPVYTPTSPKYSPTSPTYSPTSPKYSPTSPTY 1930
Query: 609 SERRLSGDLSSMPGPG--TLSVRVSPPQPILSRGRPDSNKTEN 649
S G S PG S S P +S PD + EN
Sbjct: 1931 SPTSPKGSTYSPTSPGYSPTSPTYSLTSPAIS---PDDSDEEN 1970
Score = 64.3 bits (155), Expect = 4e-10
Identities = 93/390 (23%), Positives = 141/390 (36%), Gaps = 36/390 (9%)
Query: 262 SGPSPLQLPPEDAYVGNADMIQPDLTPLQPSLDDFMDISDFFTNSRLPQPPMPSNF-PEP 320
SG SP P G+ P +P PS M S + S +P P + P+
Sbjct: 1555 SGFSPGYSPAWSPTPGSPGSPGPS-SPYIPSPGGAMSPS-YSPTSPAYEPRSPGGYTPQS 1612
Query: 321 PSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDSSAFLSSDFLLPE 380
PS+SP +S + P P S + S S + P S +S P
Sbjct: 1613 PSYSP------TSPSYSPTSPSYSPTSPNYSPTSPSYS------PTSPSYSPTSPSYSPT 1660
Query: 381 DPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPP--PFPPMAPPTALLQEEPLFSPRFPFP 438
P P P Y P + P P P P P PT+ P +SP P
Sbjct: 1661 SPSYSPTSPSYSPTSPSYSPTS--PSYSPTSPSYSPTSPSYSPTS-----PSYSPTSPSY 1713
Query: 439 TVPPAPGVSPLPAPAAFPPTPQSVP-SPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPA 497
+ P +P SP +P+ P +P P SP+ +P P + P +S P +
Sbjct: 1714 S-PTSPSYSPT-SPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYTPTSPSYS-PTSPSYS 1770
Query: 498 PSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSP 557
P+ + P +P + S T+ S +P ++ P S+ SP SP
Sbjct: 1771 PTSPNYTPTSPNYSPTSPSYSPTSPSYSPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSP 1830
Query: 558 QETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAERLSPPAPSGSERRLSGDL 617
+ T P+ +P+ P P +P+ P P + + SP +P+ S
Sbjct: 1831 SYSPTSPKYTPTSPSYSPSSPEYTPTSPKYSPTSPKYSPTSPKYSPTSPTYS-------- 1882
Query: 618 SSMPGPGTLSVRVSPPQPILSRGRPDSNKT 647
+ P S SP P+ + P + T
Sbjct: 1883 PTTPKYSPTSPTYSPTSPVYTPTSPKYSPT 1912
Score = 57.0 bits (136), Expect = 7e-08
Identities = 63/229 (27%), Positives = 89/229 (38%), Gaps = 20/229 (8%)
Query: 431 FSPRFPFPTVPPAPGVSPLPA----------PAAFPPTPQSVPSPAPTPFPIELLPLGYS 480
+SP P A G SP A A+ PTP S SP P+ P P G
Sbjct: 1531 WSPSVGSGMTPGAAGFSPSAASDASGFSPGYSPAWSPTPGSPGSPGPSS-PYIPSPGGAM 1589
Query: 481 EPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQA 540
P++ P + P +P SP G P+ +P + S T+ S +P +
Sbjct: 1590 SPSYSP--TSPAYEP--RSPGGYTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSP 1645
Query: 541 LEPPLVSSTLLRSPGSP--QETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKA 598
P ++ SP SP T P + T P+ +PT P P + +P+ P P +
Sbjct: 1646 TSPSYSPTSPSYSPTSPSYSPTSPSYSPT--SPSYSPTSPSYSPTSPSYSPTSPSYSPTS 1703
Query: 599 ERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDSNKT 647
SP +PS S S +S P S SP P S P+ + T
Sbjct: 1704 PSYSPTSPSYSPTSPSYSPTS-PSYSPTSPSYSPTSPSYSPTSPNYSPT 1751
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.135 0.423
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 46,907,255
Number of Sequences: 37866
Number of extensions: 3519359
Number of successful extensions: 72334
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 660
Number of HSP's successfully gapped in prelim test: 2116
Number of HSP's that attempted gapping in prelim test: 21723
Number of HSP's gapped (non-prelim): 20970
length of query: 833
length of database: 18,247,518
effective HSP length: 111
effective length of query: 722
effective length of database: 14,044,392
effective search space: 10140051024
effective search space used: 10140051024
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.