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Search of human proteins with 14589876
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|14589876 embryonal Fyn-associated substrate isoform 2 [Homo
sapiens]
(468 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|14589876 embryonal Fyn-associated substrate isoform 2 [Homo s... 962 0.0
gi|5031681 embryonal Fyn-associated substrate isoform 1 [Homo sa... 952 0.0
gi|44662836 breast cancer anti-estrogen resistance 1 [Homo sapiens] 140 2e-33
gi|215422375 neural precursor cell expressed, developmentally do... 117 2e-26
gi|5453680 neural precursor cell expressed, developmentally down... 117 2e-26
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 71 2e-12
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 67 3e-11
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 67 5e-11
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 67 5e-11
gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [... 65 1e-10
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 65 2e-10
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 65 2e-10
gi|110832843 TBP-associated factor 4 [Homo sapiens] 64 2e-10
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 63 7e-10
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 63 7e-10
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] 62 1e-09
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 62 1e-09
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 62 1e-09
gi|47132519 Ras association and pleckstrin homology domains 1 is... 61 2e-09
gi|150417989 cyclin K isoform 1 [Homo sapiens] 61 2e-09
gi|54860079 nadrin isoform 1 [Homo sapiens] 60 3e-09
gi|160707881 formin 2 [Homo sapiens] 60 6e-09
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 59 7e-09
gi|150170670 piccolo isoform 2 [Homo sapiens] 59 1e-08
gi|150378539 piccolo isoform 1 [Homo sapiens] 59 1e-08
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 58 2e-08
gi|163965366 nascent polypeptide-associated complex alpha subuni... 58 2e-08
gi|33356148 formin-like 1 [Homo sapiens] 58 2e-08
gi|54860105 nadrin isoform 2 [Homo sapiens] 57 4e-08
gi|110556644 zinc finger protein, multitype 1 [Homo sapiens] 57 4e-08
>gi|14589876 embryonal Fyn-associated substrate isoform 2 [Homo
sapiens]
Length = 468
Score = 962 bits (2488), Expect = 0.0
Identities = 468/468 (100%), Positives = 468/468 (100%)
Query: 1 MAIATSVYVVPPPARPCPTSGPPAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPT 60
MAIATSVYVVPPPARPCPTSGPPAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPT
Sbjct: 1 MAIATSVYVVPPPARPCPTSGPPAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPT 60
Query: 61 ALRVPSSGPYDCPASFSHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGREPG 120
ALRVPSSGPYDCPASFSHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGREPG
Sbjct: 61 ALRVPSSGPYDCPASFSHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGREPG 120
Query: 121 PPIYAAPSNLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALA 180
PPIYAAPSNLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALA
Sbjct: 121 PPIYAAPSNLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALA 180
Query: 181 SHDQDTLAQLLARSPPPPHRPRLPSAESLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQ 240
SHDQDTLAQLLARSPPPPHRPRLPSAESLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQ
Sbjct: 181 SHDQDTLAQLLARSPPPPHRPRLPSAESLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQ 240
Query: 241 DRPLPPPPPRLPGYGGPKVEGDPEGREMEDDPAGHHNEYEGIPMAEEYDYVHLKGMDKAQ 300
DRPLPPPPPRLPGYGGPKVEGDPEGREMEDDPAGHHNEYEGIPMAEEYDYVHLKGMDKAQ
Sbjct: 241 DRPLPPPPPRLPGYGGPKVEGDPEGREMEDDPAGHHNEYEGIPMAEEYDYVHLKGMDKAQ 300
Query: 301 GSRPPDQACTGDPELPERGMPAPQEALSPGEPLVVSTGDLQLLYFYAGQCQSHYSALQAA 360
GSRPPDQACTGDPELPERGMPAPQEALSPGEPLVVSTGDLQLLYFYAGQCQSHYSALQAA
Sbjct: 301 GSRPPDQACTGDPELPERGMPAPQEALSPGEPLVVSTGDLQLLYFYAGQCQSHYSALQAA 360
Query: 361 VAALMSSTQANQPPRLFVPHSKRVVVAAHRLVFVGDTLGRLAASAPLRAQVRAAGTALGQ 420
VAALMSSTQANQPPRLFVPHSKRVVVAAHRLVFVGDTLGRLAASAPLRAQVRAAGTALGQ
Sbjct: 361 VAALMSSTQANQPPRLFVPHSKRVVVAAHRLVFVGDTLGRLAASAPLRAQVRAAGTALGQ 420
Query: 421 ALRATVLAVKGAALGYPSSPAIQEMVQCVTELAGQALQFTTLLTSLAP 468
ALRATVLAVKGAALGYPSSPAIQEMVQCVTELAGQALQFTTLLTSLAP
Sbjct: 421 ALRATVLAVKGAALGYPSSPAIQEMVQCVTELAGQALQFTTLLTSLAP 468
>gi|5031681 embryonal Fyn-associated substrate isoform 1 [Homo
sapiens]
Length = 561
Score = 952 bits (2462), Expect = 0.0
Identities = 462/462 (100%), Positives = 462/462 (100%)
Query: 7 VYVVPPPARPCPTSGPPAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPS 66
VYVVPPPARPCPTSGPPAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPS
Sbjct: 100 VYVVPPPARPCPTSGPPAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPS 159
Query: 67 SGPYDCPASFSHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAA 126
SGPYDCPASFSHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAA
Sbjct: 160 SGPYDCPASFSHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAA 219
Query: 127 PSNLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDT 186
PSNLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDT
Sbjct: 220 PSNLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDT 279
Query: 187 LAQLLARSPPPPHRPRLPSAESLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQDRPLPP 246
LAQLLARSPPPPHRPRLPSAESLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQDRPLPP
Sbjct: 280 LAQLLARSPPPPHRPRLPSAESLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQDRPLPP 339
Query: 247 PPPRLPGYGGPKVEGDPEGREMEDDPAGHHNEYEGIPMAEEYDYVHLKGMDKAQGSRPPD 306
PPPRLPGYGGPKVEGDPEGREMEDDPAGHHNEYEGIPMAEEYDYVHLKGMDKAQGSRPPD
Sbjct: 340 PPPRLPGYGGPKVEGDPEGREMEDDPAGHHNEYEGIPMAEEYDYVHLKGMDKAQGSRPPD 399
Query: 307 QACTGDPELPERGMPAPQEALSPGEPLVVSTGDLQLLYFYAGQCQSHYSALQAAVAALMS 366
QACTGDPELPERGMPAPQEALSPGEPLVVSTGDLQLLYFYAGQCQSHYSALQAAVAALMS
Sbjct: 400 QACTGDPELPERGMPAPQEALSPGEPLVVSTGDLQLLYFYAGQCQSHYSALQAAVAALMS 459
Query: 367 STQANQPPRLFVPHSKRVVVAAHRLVFVGDTLGRLAASAPLRAQVRAAGTALGQALRATV 426
STQANQPPRLFVPHSKRVVVAAHRLVFVGDTLGRLAASAPLRAQVRAAGTALGQALRATV
Sbjct: 460 STQANQPPRLFVPHSKRVVVAAHRLVFVGDTLGRLAASAPLRAQVRAAGTALGQALRATV 519
Query: 427 LAVKGAALGYPSSPAIQEMVQCVTELAGQALQFTTLLTSLAP 468
LAVKGAALGYPSSPAIQEMVQCVTELAGQALQFTTLLTSLAP
Sbjct: 520 LAVKGAALGYPSSPAIQEMVQCVTELAGQALQFTTLLTSLAP 561
>gi|44662836 breast cancer anti-estrogen resistance 1 [Homo sapiens]
Length = 870
Score = 140 bits (354), Expect = 2e-33
Identities = 160/541 (29%), Positives = 220/541 (40%), Gaps = 107/541 (19%)
Query: 4 ATSVYVVPPPARPCPTSGPPAGPCPPSPDLIYKIPRASGTQLAAPRDALE-------VYD 56
A VY VPPPA P PP G P P +Y +PR + P + + VY
Sbjct: 358 AEDVYDVPPPA-PDLYDVPP-GLRRPGPGTLYDVPR----ERVLPPEVADGGVVDSGVYA 411
Query: 57 VPPTALR-VPSSGPYDCPASF-----SHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEP- 109
VPP A R P+ G +S S + + PG + P ++ + + A L+
Sbjct: 412 VPPPAEREAPAEGKRLSASSTGSTRSSQSASSLEVAGPGRE--PLELEVAVEALARLQQG 469
Query: 110 ---------DLEWEGG-----REPGPPIYAAPSNLKRASALLNLYEAPEELL-----ADG 150
DL G R P P +L+ A A + A ELL A G
Sbjct: 470 VSATVAHLLDLAGSAGATGSWRSPSEPQEPLVQDLQAAVAAVQ--SAVHELLEFARSAVG 527
Query: 151 EGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQ-------------DTLAQLLARSPPP 197
T + L + + L +H Q + L +L+A S
Sbjct: 528 NAAHTSDRALHAKL-SRQLQKMEDVHQTLVAHGQALDAGRGGSGATLEDLDRLVACSRAV 586
Query: 198 PHRPRL------PSAESLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQDRPLPPPPPRL 251
P + +A L RR P PE P+P + SIQ RPLP PP
Sbjct: 587 PEDAKQLASFLHGNASLLFRRTKATAPGPEGGGTLH-PNPTD-KTSSIQSRPLPSPPKFT 644
Query: 252 PGYGGPKVEGDPEGREMEDDPAGHHNEYEGIPMAEEYDYVHLKG---MDKAQGSRPPDQA 308
+D P G + EG M E+YDYVHL+G +K Q +
Sbjct: 645 S----------------QDSPDGQYENSEGGWM-EDYDYVHLQGKEEFEKTQKELLEKGS 687
Query: 309 CT--GDPELPERGMP--------------------APQEALSPGEPLVVSTGDLQLLYFY 346
T G +L + + P + L+PG + D QLL FY
Sbjct: 688 ITRQGKSQLELQQLKQFERLEQEVSRPIDHDLANWTPAQPLAPGRTGGLGPSDRQLLLFY 747
Query: 347 AGQCQSHYSALQAAVAALMSSTQANQPPRLFVPHSKRVVVAAHRLVFVGDTLGRLAASAP 406
QC+++ + L AV A ++ NQPP++FV HSK V+++AH+LVF+GDTL R A +A
Sbjct: 748 LEQCEANLTTLTNAVDAFFTAVATNQPPKIFVAHSKFVILSAHKLVFIGDTLSRQAKAAD 807
Query: 407 LRAQVRAAGTALGQALRATVLAVKGAALGYPSSPAIQEMVQCVTELAGQALQFTTLLTSL 466
+R+QV L LR V K AAL YPS A Q+MV+ V EL QF +L L
Sbjct: 808 VRSQVTHYSNLLCDLLRGIVATTKAAALQYPSPSAAQDMVERVKELGHSTQQFRRVLGQL 867
Query: 467 A 467
A
Sbjct: 868 A 868
Score = 42.7 bits (99), Expect = 7e-04
Identities = 93/383 (24%), Positives = 131/383 (34%), Gaps = 94/383 (24%)
Query: 13 PARPCPTSGPPAGPCPPSPDLIYKIPRASGTQLAAPR------DALEVYDVPPTA----L 62
PA P P GPPA P P P L P AS P D++ + P A
Sbjct: 71 PAGPGP--GPPATPAQPQPGLHAPAPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQGLY 128
Query: 63 RVPSSGP-YDCPAS--------------FSHPLTRVAPQPPGEDDAPYDVPLTPKPPAEL 107
+VP P + P + F P T + PPG D+ P P A +
Sbjct: 129 QVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVPPGPGGPAQDIYQVP-PSAGM 187
Query: 108 EPDL----------EWEGGREPGPPIYAAPSNL------KRASALLNLYEAPEELLADGE 151
D+ WEG + P + P+ + + A + Y+ P LLA G
Sbjct: 188 GHDIYQVPPSMDTRSWEGTKPPAKVV--VPTRVGQGYVYEAAQPEQDEYDIPRHLLAPG- 244
Query: 152 GGGTDEGIYDVPLL--------GPEAPPSPEPPGALASHDQDTLAQLLARSPPPPHRPRL 203
+ IYDVP + G E +P P + +D L ++ PP L
Sbjct: 245 ----PQDIYDVPPVRGLLPSQYGQEVYDTP-PMAVKGPNGRDPLLEVY--DVPPSVEKGL 297
Query: 204 PSAESLSRRPLP---ALPVPEAP----SPSPVPSPA--------PGRKGSIQDRPLPPPP 248
P + + +P + VP+ P VP PA P R + P P P
Sbjct: 298 PPSNHHAVYDVPPSVSKDVPDGPLLREETYDVP-PAFAKAKPFDPARTPLVLAAPPPDSP 356
Query: 249 PRLPGYGGPKVEGDPEGREMEDDPAGHHNEYEGIPMAEEYDYVHLKGMDKAQGSRPPDQA 308
P Y P P ++ D P G G YD + + PP+ A
Sbjct: 357 PAEDVYDVP-----PPAPDLYDVPPGLRRPGPG----TLYDVPRERVL-------PPEVA 400
Query: 309 CTGDPELPERGMPAPQEALSPGE 331
G + +P P E +P E
Sbjct: 401 DGGVVDSGVYAVPPPAEREAPAE 423
>gi|215422375 neural precursor cell expressed, developmentally
down-regulated 9 isoform 3 [Homo sapiens]
Length = 834
Score = 117 bits (294), Expect = 2e-26
Identities = 79/229 (34%), Positives = 115/229 (50%), Gaps = 24/229 (10%)
Query: 263 PEGREMEDDPAGHHNEYEGIPMAEEYDYVHLKGMDK---------------AQGSRPPDQ 307
P G E P ++ ++YDYVHL+G ++ Q +
Sbjct: 604 PPGLSKEQAPDCSSSDGSERSWMDDYDYVHLQGKEEFERQQKELLEKENIMKQNKMQLEH 663
Query: 308 ACTGDPELPERGMPAPQE----ALSPGEPLV-----VSTGDLQLLYFYAGQCQSHYSALQ 358
+L E+ + P E P + L VS D QLL FY QC++H+ +L
Sbjct: 664 HQLSQFQLLEQEITKPVENDISKWKPSQSLPTTNSGVSAQDRQLLCFYYDQCETHFISLL 723
Query: 359 AAVAALMSSTQANQPPRLFVPHSKRVVVAAHRLVFVGDTLGRLAASAPLRAQVRAAGTAL 418
A+ AL S + QPPR+FV HSK V+++AH+LVF+GDTL R + +R +V + L
Sbjct: 724 NAIDALFSCVSSAQPPRIFVAHSKFVILSAHKLVFIGDTLTRQVTAQDIRNKVMNSSNQL 783
Query: 419 GQALRATVLAVKGAALGYPSSPAIQEMVQCVTELAGQALQFTTLLTSLA 467
+ L+ V+A K AAL YPS+ A+QEMV VT+L+ A F L +A
Sbjct: 784 CEQLKTIVMATKMAALHYPSTTALQEMVHQVTDLSRNAQLFKRSLLEMA 832
Score = 41.6 bits (96), Expect = 0.002
Identities = 69/269 (25%), Positives = 91/269 (33%), Gaps = 73/269 (27%)
Query: 7 VYVVPPPARPC--PTSGPPAG-----PCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPP 59
VY VPP + TSGP G P +Y+ P R +VYD+PP
Sbjct: 131 VYQVPPSVQRSIGGTSGPHVGKKVITPVRTGHGYVYEYPS---------RYQKDVYDIPP 181
Query: 60 TALRVPSSGPYDCPAS------FSHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEW 113
+ + G YD P S FS P+ + PQ YD+P
Sbjct: 182 SHT---TQGVYDIPPSSAKGPVFSVPVGEIKPQ------GVYDIP--------------- 217
Query: 114 EGGREPGPPIYAAPSNLKRASALLNL--YEAPEELLADGEGGGTDEGIYDVPLLGPEAPP 171
P +YA P + R A L Y+ P + G EG+YD+P P
Sbjct: 218 -----PTKGVYAIPPSACRDEAGLREKDYDFPPPMRQAGRPDLRPEGVYDIP------PT 266
Query: 172 SPEPPG----ALASHDQDTLAQLLAR---SPPPPHRPRLPSAESLSRRPLPALPVPEA-- 222
+P G + D A+ +AR S P H P P A VP
Sbjct: 267 CTKPAGKDLHVKYNCDIPGAAEPVARRHQSLSPNHPP--PQLGQSVGSQNDAYDVPRGVQ 324
Query: 223 ---PSPSPVPSPAPGRKGSIQDRPLPPPP 248
P P + + D PL PP
Sbjct: 325 FLEPPAETSEKANPQERDGVYDVPLHNPP 353
>gi|5453680 neural precursor cell expressed, developmentally
down-regulated 9 isoform 1 [Homo sapiens]
Length = 834
Score = 117 bits (294), Expect = 2e-26
Identities = 79/229 (34%), Positives = 115/229 (50%), Gaps = 24/229 (10%)
Query: 263 PEGREMEDDPAGHHNEYEGIPMAEEYDYVHLKGMDK---------------AQGSRPPDQ 307
P G E P ++ ++YDYVHL+G ++ Q +
Sbjct: 604 PPGLSKEQAPDCSSSDGSERSWMDDYDYVHLQGKEEFERQQKELLEKENIMKQNKMQLEH 663
Query: 308 ACTGDPELPERGMPAPQE----ALSPGEPLV-----VSTGDLQLLYFYAGQCQSHYSALQ 358
+L E+ + P E P + L VS D QLL FY QC++H+ +L
Sbjct: 664 HQLSQFQLLEQEITKPVENDISKWKPSQSLPTTNSGVSAQDRQLLCFYYDQCETHFISLL 723
Query: 359 AAVAALMSSTQANQPPRLFVPHSKRVVVAAHRLVFVGDTLGRLAASAPLRAQVRAAGTAL 418
A+ AL S + QPPR+FV HSK V+++AH+LVF+GDTL R + +R +V + L
Sbjct: 724 NAIDALFSCVSSAQPPRIFVAHSKFVILSAHKLVFIGDTLTRQVTAQDIRNKVMNSSNQL 783
Query: 419 GQALRATVLAVKGAALGYPSSPAIQEMVQCVTELAGQALQFTTLLTSLA 467
+ L+ V+A K AAL YPS+ A+QEMV VT+L+ A F L +A
Sbjct: 784 CEQLKTIVMATKMAALHYPSTTALQEMVHQVTDLSRNAQLFKRSLLEMA 832
Score = 41.6 bits (96), Expect = 0.002
Identities = 69/269 (25%), Positives = 91/269 (33%), Gaps = 73/269 (27%)
Query: 7 VYVVPPPARPC--PTSGPPAG-----PCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPP 59
VY VPP + TSGP G P +Y+ P R +VYD+PP
Sbjct: 131 VYQVPPSVQRSIGGTSGPHVGKKVITPVRTGHGYVYEYPS---------RYQKDVYDIPP 181
Query: 60 TALRVPSSGPYDCPAS------FSHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEW 113
+ + G YD P S FS P+ + PQ YD+P
Sbjct: 182 SHT---TQGVYDIPPSSAKGPVFSVPVGEIKPQ------GVYDIP--------------- 217
Query: 114 EGGREPGPPIYAAPSNLKRASALLNL--YEAPEELLADGEGGGTDEGIYDVPLLGPEAPP 171
P +YA P + R A L Y+ P + G EG+YD+P P
Sbjct: 218 -----PTKGVYAIPPSACRDEAGLREKDYDFPPPMRQAGRPDLRPEGVYDIP------PT 266
Query: 172 SPEPPG----ALASHDQDTLAQLLAR---SPPPPHRPRLPSAESLSRRPLPALPVPEA-- 222
+P G + D A+ +AR S P H P P A VP
Sbjct: 267 CTKPAGKDLHVKYNCDIPGAAEPVARRHQSLSPNHPP--PQLGQSVGSQNDAYDVPRGVQ 324
Query: 223 ---PSPSPVPSPAPGRKGSIQDRPLPPPP 248
P P + + D PL PP
Sbjct: 325 FLEPPAETSEKANPQERDGVYDVPLHNPP 353
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 70.9 bits (172), Expect = 2e-12
Identities = 99/357 (27%), Positives = 127/357 (35%), Gaps = 61/357 (17%)
Query: 11 PPPARPCPTSGPPAGP-CPPSPDLIYKIPRASGTQLAA------PRDALEVYDVPPTALR 63
P A P P + PP P PSP + P A L P ++ PP +
Sbjct: 629 PLQAPPSPPASPPLSPLATPSP----QAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPP 684
Query: 64 VPSSG--PYDCPASFSHPLTRVAPQPPGEDD-APYDVPLTPKPPAELEPDLEWEGGREPG 120
V S P P S + P +V P PP +P P PP P L+
Sbjct: 685 VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPAS 744
Query: 121 PPIYAAPSNLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPS-------- 172
PP+ + + R LL AP + P P+APP+
Sbjct: 745 PPMSPSATPPPRVPPLL---AAPPLQVPPSPPASLPMSPLAKP--PPQAPPALATPPLQA 799
Query: 173 -PEPPGALASHDQDTLAQLLARSP---PPPHRPRLPSAESLSRRPLP-ALPVPEAPSPSP 227
P PP + + + L SP PPP P + +A L P P A P +AP P
Sbjct: 800 LPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPP 859
Query: 228 VPSP---APGRKGSIQDRPLPPPPPRLPGYGGPKVEGDPEGREMEDDPAGHHNEYEGIPM 284
P P G + ++ P PPPPP P D AGH + P
Sbjct: 860 TPGPDTSVSGPRLTLALAPGPPPPP----------SRSPSSTLSGPDLAGHSSSATSTP- 908
Query: 285 AEEYDYVHLKGMDK-----AQGSRPPD-QACTGDPELPERGMPAPQEAL--SPGEPL 333
EE L+G D A S PPD + P RG PAP A +PG PL
Sbjct: 909 -EE-----LRGYDSGPEGGAAASPPPDAELAACHPAAWSRG-PAPPLAFRGAPGAPL 958
Score = 65.1 bits (157), Expect = 1e-10
Identities = 67/256 (26%), Positives = 95/256 (37%), Gaps = 20/256 (7%)
Query: 11 PPPARPCPTSGPPAG---PCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSS 67
PP PCP PP+ P P +P I P + LA+P + +P L ++
Sbjct: 561 PPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASP----PLQGLPSPPLSPLAT 616
Query: 68 GPYDCPASFSHPLTRVAPQPPGEDD-APYDVPLTPKPPAELEPDLEWEGGREPGPPI--- 123
P P + P + P PP +P P P A L+ P PP+
Sbjct: 617 PPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAP 676
Query: 124 YAAPSNLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHD 183
++ P++ + + +AP L A P + P A P P+ P LA+
Sbjct: 677 FSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPAS--PPMSPSATPPPQAPPPLAAPP 734
Query: 184 QDTLAQLLARSP------PPPHRPRLPSAESLSRRPLPALPVPEAPSPSPVPSPAPGRKG 237
A P PPP P L +A L P P +P +P P P AP
Sbjct: 735 LQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKP-PPQAPPALA 793
Query: 238 SIQDRPLPPPPPRLPG 253
+ + LP PP PG
Sbjct: 794 TPPLQALPSPPASFPG 809
Score = 53.9 bits (128), Expect = 3e-07
Identities = 73/297 (24%), Positives = 104/297 (35%), Gaps = 50/297 (16%)
Query: 4 ATSVYVVPPPARPCPTSGPPAGPCPPSPDLIYKIPRASGT--QLAAPRDALEVYDVPPTA 61
AT + PP+ P T P A P P +P + +P T A P PP+
Sbjct: 324 ATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSL 383
Query: 62 LRVPSSGPYDCPASFSHPLTRVAPQP---------------------------PGEDDAP 94
+P P P S + P + P P P + A
Sbjct: 384 QTIP---PIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQAS 440
Query: 95 YDVPLTPKPPAELEPDLEWEGGREPGPPIYAAPSN-LKRASALLNLY--EAPEELLADGE 151
P P P L+ PP+ + S + S+ L ++ +A L +
Sbjct: 441 LTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSP 500
Query: 152 GGGTDEGIYDVPLLGPE---APPSPE-PPGALASHDQDTLAQLLARSPPPPHRPRLP-SA 206
I +P L + APPS + PP +L + + L L +PPP P +
Sbjct: 501 QAPLSSLI--MPPLETQSSLAPPSLQTPPASLTTPPLENLPSL---APPPLQTASAPLTT 555
Query: 207 ESLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQDRPLPPPPPRLPGYGGPKVEGDP 263
L P PA P P PSP+ +P P SI PPP P P ++G P
Sbjct: 556 PHLETPPCPA-PCPLQAPPSPLTTPPPETPSSI----ATPPPQAPPALASPPLQGLP 607
Score = 48.1 bits (113), Expect = 2e-05
Identities = 67/247 (27%), Positives = 84/247 (34%), Gaps = 54/247 (21%)
Query: 19 TSGPPAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGPYDCPASFSH 78
TSGP G PSP + + RA+GT++ PR A P R P+ GP +S S
Sbjct: 164 TSGPTPGT--PSPAMARR-SRAAGTEVGLPRPA------PSARPRPPTEGPRKSVSSASE 214
Query: 79 -------PLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGR-EPGPPIYAAPSNL 130
P R P G P L+ P R P P + +
Sbjct: 215 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKP 274
Query: 131 KRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPP---SPEPPGALASHDQDTL 187
K AL P A P LGP + +P P G A
Sbjct: 275 KGLQALRPPQVTPPRKDA-------------APALGPLSSSPLATPSPSGTKA------- 314
Query: 188 AQLLARSPPPPHRPRLPSAESLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQDRPLPP- 246
R PPP P +L P A P+P AP P+P S+Q P PP
Sbjct: 315 -----RPVPPPDNAATPLPATLPPSPPLATPLPLAP-------PSPSAPPSLQTLPSPPA 362
Query: 247 -PPPRLP 252
PP + P
Sbjct: 363 TPPSQAP 369
Score = 43.9 bits (102), Expect = 3e-04
Identities = 73/261 (27%), Positives = 92/261 (35%), Gaps = 46/261 (17%)
Query: 11 PPPARPCPTSGPPAGPCPPSPDL------IYKIPRASGTQLAAPRDALEVYDVPPTALRV 64
PPP P + PP PPSP + K P + LA P L+ PP +
Sbjct: 753 PPPRVPPLLAAPPL-QVPPSPPASLPMSPLAKPPPQAPPALATP--PLQALPSPPASF-- 807
Query: 65 PSSGPYDCPASFS-HPLTRVAPQPPGEDDAPYDVPLTPKPPAELE-----------PDLE 112
P P+ AS PL PQ P AP + + P PPA PD
Sbjct: 808 PGQAPFSPSASLPMSPLATPPPQAPPVLAAPL-LQVPPSPPASPTLQAPRRPPTPGPDTS 866
Query: 113 WEGGR-------EPGPPIYAAPSNLKRASALL----NLYEAPEELLADGEGGGTDEGIYD 161
G R P PP +PS+ L + PEEL G G + G
Sbjct: 867 VSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELR--GYDSGPEGGAAA 924
Query: 162 VPLLGPEAPPSPEPPGALASHDQDTLAQLLARSPPPPHRPRLP--SAESL-----SRRPL 214
P P+A + P A + LA A P P P SA+ L + P
Sbjct: 925 SP--PPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPE 982
Query: 215 PALPVPEAPSPSPVPSPAPGR 235
A P P A P P P + G+
Sbjct: 983 SATPAPGALDPGPSPGTSGGK 1003
Score = 43.5 bits (101), Expect = 4e-04
Identities = 74/294 (25%), Positives = 106/294 (36%), Gaps = 66/294 (22%)
Query: 12 PPARPCPTSGPPAGPCPP--SPDLIYKIP------RASGTQLAAPRDALEVYDVPPT-AL 62
PPA P P+ PP+ PP +P + IP + L AP L + + T +L
Sbjct: 360 PPATP-PSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSL 418
Query: 63 RVPS---------SGPYDCPASFSHPLTRVAPQPPGED--DAPYDVPLTPKPPAELEPDL 111
P+ P AS + P +R A PP AP +P +P L P +
Sbjct: 419 GSPTLQATHSFLTMSPRQTQASLTSP-SRPASTPPDSPPLQAPLSLPASPPLQTSLSPAV 477
Query: 112 EWEGGREPGPPIYAAPSNLKRA--SALLNLYEAPEEL--------LADGEGGGTDEGIYD 161
P+ A S + + L +L P E L T + +
Sbjct: 478 SPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLEN 537
Query: 162 VPLLGP---------------EAPPSPEP------PGALASHDQDTLAQLLARSPPPPHR 200
+P L P E PP P P P L + +T + + + PPP
Sbjct: 538 LPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSI---ATPPPQA 594
Query: 201 PRLPSAESLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQDRPL--PPPPPRLP 252
P +L+ PL LP +P SP+ +P P + PL PP PP P
Sbjct: 595 P-----PALASPPLQGLP---SPPLSPLATPPPQAPPXLALPPLQAPPSPPASP 640
Score = 35.8 bits (81), Expect = 0.086
Identities = 56/217 (25%), Positives = 67/217 (30%), Gaps = 40/217 (18%)
Query: 3 IATSVYVVPPPARPCPTSGPPAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTAL 62
+A + VPP PT P P P PD PR + P PP
Sbjct: 835 LAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGP---------PPPPS 885
Query: 63 RVPS---SGPYDCPASFSHPLTRVAPQPPGEDDAPY-DVPLTPKPPAELEPDLEWEGGRE 118
R PS SGP A S T + G D P +P P AEL R
Sbjct: 886 RSPSSTLSGP--DLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRG 943
Query: 119 PGPPI-----------YAAPSNLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGP 167
P PP+ + + A L +YE A G D G
Sbjct: 944 PAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPG--------- 994
Query: 168 EAPPSPEPPGALASHDQDTLAQLLARSPPPPHRPRLP 204
PSP G A+ A +RSP LP
Sbjct: 995 ---PSPGTSGGKAAAGAGAGAS--SRSPKQARLGELP 1026
>gi|155030232 proline, glutamic acid and leucine rich protein 1
[Homo sapiens]
Length = 1130
Score = 67.0 bits (162), Expect = 3e-11
Identities = 90/312 (28%), Positives = 116/312 (37%), Gaps = 81/312 (25%)
Query: 10 VPPPARPCPTSGPPAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGP 69
VPPP P P PP P P P + +P A A P P+A VPS+ P
Sbjct: 651 VPPPEAPSPFRAPPFHPPGPMPS-VGSMPSAGPMPSAGPM---------PSAGPVPSARP 700
Query: 70 ----------YDCPASFSHPLTRVAPQP----PGEDDAPYDVPLTPKPPAELEPDLEWEG 115
P S P R+ P P G ++ P P + PP + PD E G
Sbjct: 701 GPPTTANHLGLSVPGLVSVP-PRLLPGPENHRAGSNEDPILAP-SGTPPPTIPPD-ETFG 757
Query: 116 GREPGPPIYAAPSNLKRASALLNLYEAPE-ELLADGEGGGTDEGIYDVPLLGPEAPPSPE 174
GR P P A + EA + E+ + + +D+ + VP P PP P
Sbjct: 758 GRVPRP-----------AFVHYDKEEASDVEISLESD---SDDSVVIVPEGLPPLPP-PP 802
Query: 175 PPGALASHDQDTLAQLLARSPPPPHRPRLPSAESLSRRPLPALPVPEAPSPSPVPSPAPG 234
P GA +A + PP P +P+ E LPA P P P P P P P PG
Sbjct: 803 PSGATPPP--------IAPTGPPTASPPVPAKE--EPEELPAAPGP-LPPPPPPPPPVPG 851
Query: 235 RKGSIQDRPLPPPPPRL-----PGYGGPKV--------------EGDPEGREMEDDPAGH 275
P+ PPP+L PG GGP E + E E E++
Sbjct: 852 --------PVTLPPPQLVPEGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEE 903
Query: 276 HNEYEGIPMAEE 287
E E EE
Sbjct: 904 EEEEEDFEEEEE 915
Score = 39.7 bits (91), Expect = 0.006
Identities = 33/126 (26%), Positives = 46/126 (36%), Gaps = 4/126 (3%)
Query: 141 EAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQLLARSPPPPHR 200
E E+L GG +EG P L P PP PP + + L P
Sbjct: 958 EEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEE 1017
Query: 201 PRLPSAESLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQDRPLPPPP--PRLPGYGGPK 258
+A +L+ LP+ E SP P P + +++ P PP G K
Sbjct: 1018 RGADTAPTLAPEALPSQGEVEREGESPAAGPPP--QELVEEEPSAPPTLLEEETEDGSDK 1075
Query: 259 VEGDPE 264
V+ PE
Sbjct: 1076 VQPPPE 1081
Score = 31.2 bits (69), Expect = 2.1
Identities = 36/116 (31%), Positives = 47/116 (40%), Gaps = 18/116 (15%)
Query: 12 PPARPCPTSGPPAGPCP-PSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGPY 70
PPA P P S P P P P P L+ ++ GT+ R A + P AL PS G
Sbjct: 983 PPALPPPESPPKVQPEPEPEPGLLLEV-EEPGTE--EERGADTAPTLAPEAL--PSQGEV 1037
Query: 71 ----DCPASFSHPLTRVAPQPPG--------EDDAPYDVPLTPKPPAELEPDLEWE 114
+ PA+ P V +P +D V P+ PAE E + E E
Sbjct: 1038 EREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEMETETE 1093
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 66.6 bits (161), Expect = 5e-11
Identities = 100/361 (27%), Positives = 126/361 (34%), Gaps = 78/361 (21%)
Query: 4 ATSVYVVPPPARPCPTSGPPAGPC--------PPSPDLIYKIPRASGTQLAAPRDALEV- 54
AT ++ PP P T P A P PPSP + + AP +AL V
Sbjct: 376 ATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAP-NALAVH 434
Query: 55 -----YDVPPTALRVPSSGPYDCPAS--FSHPLTRVAPQPPGEDDAPYDVPLTPKPPAEL 107
+ PP+ P P+ PAS S T + PP P VP P PPA
Sbjct: 435 LLQAPFSPPPSP---PVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVP--PSPPASP 489
Query: 108 EPDLEWEGGREPGPPIYAAPSNLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGP 167
+ PP+ A P L + +AP L P
Sbjct: 490 PMSPSATPPPQAPPPLAAPPLQLAKPPP-----QAPPALAT------------------P 526
Query: 168 EAPPSPEPPGALASHDQDTLAQLLARSP---PPPHRPRLPSAESLSRRPLP-ALPVPEAP 223
P PP + + + L SP PPP P + +A L P P A P +AP
Sbjct: 527 PLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAP 586
Query: 224 SPSPVPSP---APGRKGSIQDRPLPPPPPRLPGYGGPKVEGDPEGREMEDDPAGHHNEYE 280
P P P G + ++ P PPPPP P D AGH +
Sbjct: 587 RRPPTPGPDTSVSGPRLTLALAPGPPPPP----------SRSPSSTLSGPDLAGHSSSAT 636
Query: 281 GIPMAEEYDYVHLKGMDK-----AQGSRPPD-QACTGDPELPERGMPAPQEAL--SPGEP 332
P EE L+G D A S PPD + P RG PAP A +PG P
Sbjct: 637 STP--EE-----LRGYDSGPEGGAAASPPPDAELAACHPAAWSRG-PAPPLAFRGAPGAP 688
Query: 333 L 333
L
Sbjct: 689 L 689
Score = 52.4 bits (124), Expect = 9e-07
Identities = 69/267 (25%), Positives = 96/267 (35%), Gaps = 41/267 (15%)
Query: 3 IATSVYVVPPPARPCPTSGPPAGPCPP-SPDLIYKIPRASGTQLAAPRDALEVYDVPPTA 61
+++S P P+ + PP P P S L ++ A+ LA P + PP+
Sbjct: 299 LSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQL--ATPLPLAPPSPS-----APPSL 351
Query: 62 LRVPS---SGPYDCPASFSHPLTRVA----PQPPGEDDAPYDVPLTPKPPAELEPDLEWE 114
+PS + P S P + P PP +P P PPA P L+
Sbjct: 352 QTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPL---SPLATPPPQAPPALALPPLQAP 408
Query: 115 GGREPGPPI--YAAPSNLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPS 172
PP+ A PS + ++L +AP P+ P +PP+
Sbjct: 409 PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSP------------PVQAPFSPPA 456
Query: 173 PEPPGALASHDQDTLAQLLARSPP---PPHRPRLPSAESLSRRPLPALPVPEAPSPSPVP 229
P A+ L A PP PP P P S S P P P P A P +
Sbjct: 457 SPPVSPSATPPSQAPPSLAA--PPLQVPPSPPASPPM-SPSATPPPQAPPPLAAPPLQLA 513
Query: 230 SPAPGRKGSIQDRP---LPPPPPRLPG 253
P P ++ P LP PP PG
Sbjct: 514 KPPPQAPPALATPPLQALPSPPASFPG 540
Score = 45.8 bits (107), Expect = 8e-05
Identities = 74/265 (27%), Positives = 89/265 (33%), Gaps = 49/265 (18%)
Query: 11 PPPARPCPTS-GPPAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSG- 68
PPP+ P PPA P P SP P + LAAP L+V PP + + S
Sbjct: 442 PPPSPPVQAPFSPPASP-PVSPSATP--PSQAPPSLAAP--PLQVPPSPPASPPMSPSAT 496
Query: 69 -PYDCPASFSHPLTRVAPQPPGEDDAPYDVPLT--PKPPAELEPDLEWEGGRE------- 118
P P + P ++A PP A PL P PPA +
Sbjct: 497 PPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLA 556
Query: 119 ----PGPPIYAAP----SNLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAP 170
PP+ AAP AS L P D G + P GP P
Sbjct: 557 TPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAP--GPPPP 614
Query: 171 PSPEPPGALASHD--------QDTLAQL----------LARSPPPPHRPRLPSAESLSRR 212
PS P L+ D T +L A SPPP + SR
Sbjct: 615 PSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRG 674
Query: 213 PLPALP---VPEAPSPSPVPSPAPG 234
P P L P AP P P P+ PG
Sbjct: 675 PAPPLAFRGAPGAPLPWP-PATGPG 698
Score = 43.9 bits (102), Expect = 3e-04
Identities = 65/242 (26%), Positives = 84/242 (34%), Gaps = 55/242 (22%)
Query: 19 TSGPPAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGPYDCPASFSH 78
TSGP G PSP + + RA+GT++ PR A P R P+ GP +S S
Sbjct: 164 TSGPTPGT--PSPAMARR-SRAAGTEVGLPRPA------PSARPRPPTEGPRKSVSSASE 214
Query: 79 -------PLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGR-EPGPPIYAAPSNL 130
P R P G P L+ P R P P + +
Sbjct: 215 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKP 274
Query: 131 KRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPP---SPEPPGALASHDQDTL 187
K AL P A P LGP + +P P AL
Sbjct: 275 KGLQALRPPQVTPPRKDA-------------APALGPLSSSPLATPSPSAAL-------- 313
Query: 188 AQLLARSPPPPHRPRLPSAESLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQDRPLPPP 247
+S PP P P + SL+ + A P+P AP P+P S+Q P PP
Sbjct: 314 -----QSQAPPTLPATPHSSSLTCQL--ATPLPLAP-------PSPSAPPSLQTLPSPPA 359
Query: 248 PP 249
P
Sbjct: 360 TP 361
Score = 43.9 bits (102), Expect = 3e-04
Identities = 73/271 (26%), Positives = 94/271 (34%), Gaps = 46/271 (16%)
Query: 2 AIATSVYVVPPPARPCPTSGPPAGPCPPSPD-------LIYKIPRASGTQLAAPRDALEV 54
++A VPP P P A P P +P + K P + LA P L+
Sbjct: 473 SLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATP--PLQA 530
Query: 55 YDVPPTALRVPSSGPYDCPASF-SHPLTRVAPQPPGEDDAPYDVPLTPKPPAELE----- 108
PP + P P+ AS PL PQ P AP + + P PPA
Sbjct: 531 LPSPPASF--PGQAPFSPSASLPMSPLATPPPQAPPVLAAPL-LQVPPSPPASPTLQAPR 587
Query: 109 ------PDLEWEGGR-------EPGPPIYAAPSNLKRASALL----NLYEAPEELLADGE 151
PD G R P PP +PS+ L + PEEL G
Sbjct: 588 RPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEEL--RGY 645
Query: 152 GGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQLLARSPPPPHRPRL--PSAESL 209
G + G P P+A + P A + LA A P P P SA+ L
Sbjct: 646 DSGPEGGAAASP--PPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGL 703
Query: 210 -----SRRPLPALPVPEAPSPSPVPSPAPGR 235
+ P A P P A P P P + G+
Sbjct: 704 CTIYETEGPESATPAPGALDPGPSPGTSGGK 734
Score = 35.8 bits (81), Expect = 0.086
Identities = 56/217 (25%), Positives = 67/217 (30%), Gaps = 40/217 (18%)
Query: 3 IATSVYVVPPPARPCPTSGPPAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTAL 62
+A + VPP PT P P P PD PR + P PP
Sbjct: 566 LAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGP---------PPPPS 616
Query: 63 RVPS---SGPYDCPASFSHPLTRVAPQPPGEDDAPY-DVPLTPKPPAELEPDLEWEGGRE 118
R PS SGP A S T + G D P +P P AEL R
Sbjct: 617 RSPSSTLSGP--DLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRG 674
Query: 119 PGPPI-----------YAAPSNLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGP 167
P PP+ + + A L +YE A G D G
Sbjct: 675 PAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPG--------- 725
Query: 168 EAPPSPEPPGALASHDQDTLAQLLARSPPPPHRPRLP 204
PSP G A+ A +RSP LP
Sbjct: 726 ---PSPGTSGGKAAAGAGAGAS--SRSPKQARLGELP 757
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 66.6 bits (161), Expect = 5e-11
Identities = 100/361 (27%), Positives = 126/361 (34%), Gaps = 78/361 (21%)
Query: 4 ATSVYVVPPPARPCPTSGPPAGPC--------PPSPDLIYKIPRASGTQLAAPRDALEV- 54
AT ++ PP P T P A P PPSP + + AP +AL V
Sbjct: 337 ATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAP-NALAVH 395
Query: 55 -----YDVPPTALRVPSSGPYDCPAS--FSHPLTRVAPQPPGEDDAPYDVPLTPKPPAEL 107
+ PP+ P P+ PAS S T + PP P VP P PPA
Sbjct: 396 LLQAPFSPPPSP---PVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVP--PSPPASP 450
Query: 108 EPDLEWEGGREPGPPIYAAPSNLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGP 167
+ PP+ A P L + +AP L P
Sbjct: 451 PMSPSATPPPQAPPPLAAPPLQLAKPPP-----QAPPALAT------------------P 487
Query: 168 EAPPSPEPPGALASHDQDTLAQLLARSP---PPPHRPRLPSAESLSRRPLP-ALPVPEAP 223
P PP + + + L SP PPP P + +A L P P A P +AP
Sbjct: 488 PLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAP 547
Query: 224 SPSPVPSP---APGRKGSIQDRPLPPPPPRLPGYGGPKVEGDPEGREMEDDPAGHHNEYE 280
P P P G + ++ P PPPPP P D AGH +
Sbjct: 548 RRPPTPGPDTSVSGPRLTLALAPGPPPPP----------SRSPSSTLSGPDLAGHSSSAT 597
Query: 281 GIPMAEEYDYVHLKGMDK-----AQGSRPPD-QACTGDPELPERGMPAPQEAL--SPGEP 332
P EE L+G D A S PPD + P RG PAP A +PG P
Sbjct: 598 STP--EE-----LRGYDSGPEGGAAASPPPDAELAACHPAAWSRG-PAPPLAFRGAPGAP 649
Query: 333 L 333
L
Sbjct: 650 L 650
Score = 53.1 bits (126), Expect = 5e-07
Identities = 73/289 (25%), Positives = 95/289 (32%), Gaps = 56/289 (19%)
Query: 2 AIATSVYVVPPPARPCPTS-GPPAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPT 60
++++S + PAR P++ G P P PS P+ G Q P PP
Sbjct: 232 SLSSSATPLSSPARSGPSARGTPRAPAHPSQ------PKPKGLQALRPPQV-----TPPR 280
Query: 61 ALRVPSSGPYDCPASFSHPLTRVAPQPPGEDDAPYDVPLTPKPPAEL---------EPDL 111
P+ GP S PL +P P AP + P PPA P L
Sbjct: 281 KDAAPALGPLS-----SSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTL 335
Query: 112 EWEGGREPGPPIY---AAPSNLKRASALLNLYEAPEE--------LLADGEGGGTDEGIY 160
+ P PP+ P A AL L P L ++
Sbjct: 336 QATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVH 395
Query: 161 ----------DVPLLGPEAPPSPEPPGALASHDQDTLAQLLARSPP---PPHRPRLPSAE 207
P+ P +PP+ P A+ L A PP PP P P
Sbjct: 396 LLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAA--PPLQVPPSPPASPPM- 452
Query: 208 SLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQDRP---LPPPPPRLPG 253
S S P P P P A P + P P ++ P LP PP PG
Sbjct: 453 SPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPG 501
Score = 50.1 bits (118), Expect = 4e-06
Identities = 69/248 (27%), Positives = 87/248 (35%), Gaps = 40/248 (16%)
Query: 19 TSGPPAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGPYDCPASFSH 78
TSGP G PSP + + RA+GT++ PR A P R P+ GP +S S
Sbjct: 155 TSGPTPGT--PSPAMARR-SRAAGTEVGLPRPA------PSARPRPPTEGPRKSVSSASE 205
Query: 79 -------PLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGR-EPGPPIYAAPSNL 130
P R P G P L+ P R P P + +
Sbjct: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKP 265
Query: 131 KRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQL 190
K AL P A G P P APPSP P +L +
Sbjct: 266 KGLQALRPPQVTPPRKDAAPALGPLSSSPLATP--SPSAPPSPSAPPSLQT--------- 314
Query: 191 LARSPPPPHRPRLPSAESLSRRPLPA----LPVPEAPSPSPVPSPAPGRKGSIQDRPL-- 244
P PP P + SL L A LP +P SP+ +P P ++ PL
Sbjct: 315 ---LPSPPATPPSQATTSLGSPTLQATHSFLP---SPPLSPLATPPPQAPPALALPPLQA 368
Query: 245 PPPPPRLP 252
PP PP P
Sbjct: 369 PPSPPASP 376
Score = 45.8 bits (107), Expect = 8e-05
Identities = 74/265 (27%), Positives = 89/265 (33%), Gaps = 49/265 (18%)
Query: 11 PPPARPCPTS-GPPAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSG- 68
PPP+ P PPA P P SP P + LAAP L+V PP + + S
Sbjct: 403 PPPSPPVQAPFSPPASP-PVSPSATP--PSQAPPSLAAP--PLQVPPSPPASPPMSPSAT 457
Query: 69 -PYDCPASFSHPLTRVAPQPPGEDDAPYDVPLT--PKPPAELEPDLEWEGGRE------- 118
P P + P ++A PP A PL P PPA +
Sbjct: 458 PPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLA 517
Query: 119 ----PGPPIYAAP----SNLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAP 170
PP+ AAP AS L P D G + P GP P
Sbjct: 518 TPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAP--GPPPP 575
Query: 171 PSPEPPGALASHD--------QDTLAQL----------LARSPPPPHRPRLPSAESLSRR 212
PS P L+ D T +L A SPPP + SR
Sbjct: 576 PSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRG 635
Query: 213 PLPALP---VPEAPSPSPVPSPAPG 234
P P L P AP P P P+ PG
Sbjct: 636 PAPPLAFRGAPGAPLPWP-PATGPG 659
Score = 43.9 bits (102), Expect = 3e-04
Identities = 73/271 (26%), Positives = 94/271 (34%), Gaps = 46/271 (16%)
Query: 2 AIATSVYVVPPPARPCPTSGPPAGPCPPSPD-------LIYKIPRASGTQLAAPRDALEV 54
++A VPP P P A P P +P + K P + LA P L+
Sbjct: 434 SLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATP--PLQA 491
Query: 55 YDVPPTALRVPSSGPYDCPASF-SHPLTRVAPQPPGEDDAPYDVPLTPKPPAELE----- 108
PP + P P+ AS PL PQ P AP + + P PPA
Sbjct: 492 LPSPPASF--PGQAPFSPSASLPMSPLATPPPQAPPVLAAPL-LQVPPSPPASPTLQAPR 548
Query: 109 ------PDLEWEGGR-------EPGPPIYAAPSNLKRASALL----NLYEAPEELLADGE 151
PD G R P PP +PS+ L + PEEL G
Sbjct: 549 RPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEEL--RGY 606
Query: 152 GGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQLLARSPPPPHRPRL--PSAESL 209
G + G P P+A + P A + LA A P P P SA+ L
Sbjct: 607 DSGPEGGAAASP--PPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGL 664
Query: 210 -----SRRPLPALPVPEAPSPSPVPSPAPGR 235
+ P A P P A P P P + G+
Sbjct: 665 CTIYETEGPESATPAPGALDPGPSPGTSGGK 695
Score = 35.8 bits (81), Expect = 0.086
Identities = 56/217 (25%), Positives = 67/217 (30%), Gaps = 40/217 (18%)
Query: 3 IATSVYVVPPPARPCPTSGPPAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTAL 62
+A + VPP PT P P P PD PR + P PP
Sbjct: 527 LAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGP---------PPPPS 577
Query: 63 RVPS---SGPYDCPASFSHPLTRVAPQPPGEDDAPY-DVPLTPKPPAELEPDLEWEGGRE 118
R PS SGP A S T + G D P +P P AEL R
Sbjct: 578 RSPSSTLSGP--DLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRG 635
Query: 119 PGPPI-----------YAAPSNLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGP 167
P PP+ + + A L +YE A G D G
Sbjct: 636 PAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPG--------- 686
Query: 168 EAPPSPEPPGALASHDQDTLAQLLARSPPPPHRPRLP 204
PSP G A+ A +RSP LP
Sbjct: 687 ---PSPGTSGGKAAAGAGAGAS--SRSPKQARLGELP 718
>gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo
sapiens]
Length = 1636
Score = 65.5 bits (158), Expect = 1e-10
Identities = 87/333 (26%), Positives = 111/333 (33%), Gaps = 71/333 (21%)
Query: 12 PPARPCPTSGPPAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGPYD 71
P P P PP P PP L +G + P +P P GP
Sbjct: 897 PRPNPTPAPPPPCFPVPPPQPLPTPYTYPAGAKQPIPAQHHFSSGIP-AGFPAPRIGPQP 955
Query: 72 CPASFSHPLTRVAPQPPGEDDAPYDVP--LTPKPPAELEPDLEWEGGREPG------PPI 123
P HP PQPP + P P P+ P L P + +PG PP+
Sbjct: 956 QPHPQPHPSQAFGPQPP-QQPLPLQHPHLFPPQAPGLLPPQSPYPYAPQPGVLGQPPPPL 1014
Query: 124 YAAPSNLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHD 183
+ LY P + G +P P P P PP
Sbjct: 1015 HT------------QLYPGPAQDPLPAHSGA-------LPFPSPGPPQPPHPP------- 1048
Query: 184 QDTLAQLLARSPPPPHRPRLPSAESLSRR---------PLPALPVPEAPSPSPVPSPAPG 234
LA P P RP P A L+ R P P L VP +P+PSP P P P
Sbjct: 1049 -------LAYGPAPSTRPMGPQAAPLTIRGPSSAGQSTPSPHL-VP-SPAPSPGPGPVPP 1099
Query: 235 RKGSIQDRPLPPPPPRLPGYGGPKVEGDPEGREMEDDPAGHHNEYEGIPMAEEYDYVHLK 294
R + + PPP R + PE + G + G P+ +
Sbjct: 1100 RPPAAE----PPPCLRRGAAAADLLSSSPESQH-----GGTQSPGGGQPLLQP------T 1144
Query: 295 GMDKAQGSRPPD-QACTGDP-ELPERGMPAPQE 325
+D A+G RP + DP E PER QE
Sbjct: 1145 KVDAAEGRRPQALRLIERDPYEHPERLRQLQQE 1177
Score = 43.9 bits (102), Expect = 3e-04
Identities = 70/289 (24%), Positives = 109/289 (37%), Gaps = 57/289 (19%)
Query: 67 SGPYDCPASFSHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAA 126
SGP P ++S P + P+ PG P+ +P+ P P P E G P ++
Sbjct: 788 SGPLP-PGTYSGPTQLIQPRAPG----PHAMPVAPGPALYPAPAYTPELGLVPR----SS 838
Query: 127 PSNLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPE---PPGALASHD 183
P + +S + + AP P+ G + P P+ P A+A
Sbjct: 839 PQHGVVSSPYVGVGPAP-------------------PVAGLPSAPPPQFSGPELAMAVRP 879
Query: 184 QDTLAQLLARSPPPPHRPRLPSAESLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQDRP 243
T + ++P P H P+ P PA P P P P P P P P + +P
Sbjct: 880 ATTTVDSI-QAPIPSHTAPRPN-------PTPAPPPPCFPVPPPQPLPTPYTYPAGAKQP 931
Query: 244 LPPP---PPRLP-GYGGPKVEGDPEGREMEDDPAGHHNEYEGIPMAEE---YDYVHLKGM 296
+P +P G+ P++ G + + P H ++ G ++ + HL
Sbjct: 932 IPAQHHFSSGIPAGFPAPRI-----GPQPQPHPQPHPSQAFGPQPPQQPLPLQHPHL-FP 985
Query: 297 DKAQGSRPPDQACTGDPELPERGMPAP--QEALSPG---EPLVVSTGDL 340
+A G PP P+ G P P L PG +PL +G L
Sbjct: 986 PQAPGLLPPQSPYPYAPQPGVLGQPPPPLHTQLYPGPAQDPLPAHSGAL 1034
Score = 35.4 bits (80), Expect = 0.11
Identities = 28/91 (30%), Positives = 37/91 (40%), Gaps = 12/91 (13%)
Query: 161 DVPLLGPEAPP---SPEPPGALASHDQDTLAQLLARSPPPPHRPRLPSAESLSRRPLPAL 217
DVP+ +A S PPG L S +A P P P LP A P+P+
Sbjct: 1492 DVPISSIQATIAKLSIRPPGGLESP--------VASLPGPAEPPGLPPASLPESTPIPSS 1543
Query: 218 PVPEAPSPSPVPSPAPGRKGSIQDRPLPPPP 248
P SP P +P P + + + P PP
Sbjct: 1544 SPPPLSSPLP-EAPQPKEEPPVPEAPSSGPP 1573
Score = 35.0 bits (79), Expect = 0.15
Identities = 29/78 (37%), Positives = 35/78 (44%), Gaps = 13/78 (16%)
Query: 153 GGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQLLARSPPPPHRPRLPSAESLSRR 212
GG + + +P GP PP P AS + T + + SPPP P LP A
Sbjct: 1511 GGLESPVASLP--GPAEPPGLPP----ASLPEST--PIPSSSPPPLSSP-LPEAPQPKEE 1561
Query: 213 PLPALPVPEAPSPSPVPS 230
P PVPEAPS P S
Sbjct: 1562 P----PVPEAPSSGPPSS 1575
Score = 31.6 bits (70), Expect = 1.6
Identities = 42/150 (28%), Positives = 54/150 (36%), Gaps = 30/150 (20%)
Query: 130 LKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQ 189
L+R + EA + L D E L + PP P P L +++ A
Sbjct: 690 LERTQSTCQAREAARQQLLDRE-------------LKKKPPPRPTAPKPLLPRREESEA- 735
Query: 190 LLARSPP------PPHR---PRLPSAESLSRRPL--PALPVPEAPSPSP----VPSPAPG 234
+ A PP PP PRLP S PL P P P + P P P P
Sbjct: 736 VEAGDPPEELRSLPPDMVAGPRLPDTFLGSATPLHFPPSPFPSSTGPGPHYLSGPLPPGT 795
Query: 235 RKGSIQ-DRPLPPPPPRLPGYGGPKVEGDP 263
G Q +P P P +P GP + P
Sbjct: 796 YSGPTQLIQPRAPGPHAMPVAPGPALYPAP 825
>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
Length = 1263
Score = 64.7 bits (156), Expect = 2e-10
Identities = 66/236 (27%), Positives = 85/236 (36%), Gaps = 61/236 (25%)
Query: 53 EVYDVPPTALRVPSSGPYDCPASFSHPL-----TRVAPQP-PGEDDAPYDVPLTPKPPAE 106
E+ + A+ VP S P P + PL T + P P PG+ P P P PP
Sbjct: 552 EMASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPP 611
Query: 107 LEPDLEWEGGREPGPPIYAAPSNLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLG 166
L PG ++P +L +A+ P L D
Sbjct: 612 L-----------PGGVCISSPPSLPGGTAI----SPPPPLSGDAT--------------- 641
Query: 167 PEAPPSPEPPGALASHDQDTLAQLLARSPPPPHRPRLPSAESLSRRPLPALPVPEAPSPS 226
PP P P + +L A PPPP LP + +R P P P+P +
Sbjct: 642 --IPPPPPLPEGVGIPSPSSLPGGTAIPPPPP----LPGS---ARIPPPPPPLPGSAGIP 692
Query: 227 PVPSPAPGRKGSIQDRPLPPPPPRLPG----------YGGPKVEGDPEGREMEDDP 272
P P P PG G +PPPPP LPG GGP + P G M P
Sbjct: 693 PPPPPLPGEAG------MPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPP 742
Score = 49.7 bits (117), Expect = 6e-06
Identities = 71/260 (27%), Positives = 88/260 (33%), Gaps = 91/260 (35%)
Query: 9 VVPPPARPCPTSGPPAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSG 68
++PPP P ++ PP P PP P PP V S
Sbjct: 586 IIPPPPAPGDSTTPPPPPPPPPPP-------------------------PPLPGGVCISS 620
Query: 69 PYDCPASFSHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAAPS 128
P P T ++P PP DA + P PP EG P +PS
Sbjct: 621 PPSLPGG-----TAISPPPPLSGDA----TIPPPPPLP-------EGVGIP------SPS 658
Query: 129 NLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDTLA 188
+L +A+ P L G +P PP P PG+
Sbjct: 659 SLPGGTAI----PPPPPL----------PGSARIP------PPPPPLPGS---------- 688
Query: 189 QLLARSPPPPHRPRLPSAESLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQDRP---LP 245
A PPPP P LP + P P P+P P P P P PG G P +P
Sbjct: 689 ---AGIPPPP--PPLPGEAGM---PPPPPPLPGGPG-IPPPPPFPGGPGIPPPPPGMGMP 739
Query: 246 PPPPRLPGYGGPKVEGDPEG 265
PPPP G+G P P G
Sbjct: 740 PPPPF--GFGVPAAPVLPFG 757
>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
Length = 1272
Score = 64.7 bits (156), Expect = 2e-10
Identities = 66/236 (27%), Positives = 85/236 (36%), Gaps = 61/236 (25%)
Query: 53 EVYDVPPTALRVPSSGPYDCPASFSHPL-----TRVAPQP-PGEDDAPYDVPLTPKPPAE 106
E+ + A+ VP S P P + PL T + P P PG+ P P P PP
Sbjct: 561 EMASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPP 620
Query: 107 LEPDLEWEGGREPGPPIYAAPSNLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLG 166
L PG ++P +L +A+ P L D
Sbjct: 621 L-----------PGGVCISSPPSLPGGTAI----SPPPPLSGDAT--------------- 650
Query: 167 PEAPPSPEPPGALASHDQDTLAQLLARSPPPPHRPRLPSAESLSRRPLPALPVPEAPSPS 226
PP P P + +L A PPPP LP + +R P P P+P +
Sbjct: 651 --IPPPPPLPEGVGIPSPSSLPGGTAIPPPPP----LPGS---ARIPPPPPPLPGSAGIP 701
Query: 227 PVPSPAPGRKGSIQDRPLPPPPPRLPG----------YGGPKVEGDPEGREMEDDP 272
P P P PG G +PPPPP LPG GGP + P G M P
Sbjct: 702 PPPPPLPGEAG------MPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPP 751
Score = 49.7 bits (117), Expect = 6e-06
Identities = 71/260 (27%), Positives = 88/260 (33%), Gaps = 91/260 (35%)
Query: 9 VVPPPARPCPTSGPPAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSG 68
++PPP P ++ PP P PP P PP V S
Sbjct: 595 IIPPPPAPGDSTTPPPPPPPPPPP-------------------------PPLPGGVCISS 629
Query: 69 PYDCPASFSHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAAPS 128
P P T ++P PP DA + P PP EG P +PS
Sbjct: 630 PPSLPGG-----TAISPPPPLSGDA----TIPPPPPLP-------EGVGIP------SPS 667
Query: 129 NLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDTLA 188
+L +A+ P L G +P PP P PG+
Sbjct: 668 SLPGGTAI----PPPPPL----------PGSARIP------PPPPPLPGS---------- 697
Query: 189 QLLARSPPPPHRPRLPSAESLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQDRP---LP 245
A PPPP P LP + P P P+P P P P P PG G P +P
Sbjct: 698 ---AGIPPPP--PPLPGEAGM---PPPPPPLPGGPG-IPPPPPFPGGPGIPPPPPGMGMP 748
Query: 246 PPPPRLPGYGGPKVEGDPEG 265
PPPP G+G P P G
Sbjct: 749 PPPPF--GFGVPAAPVLPFG 766
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 64.3 bits (155), Expect = 2e-10
Identities = 74/275 (26%), Positives = 94/275 (34%), Gaps = 53/275 (19%)
Query: 11 PPPARPCPTSGPPAGPCPPSP--DLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSG 68
PP R P G P P PPSP L+ P +L P + P A ++G
Sbjct: 90 PPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAG 149
Query: 69 PYDCPASFSHPL------TRVAPQP-PGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGP 121
P PA + P R P P PG P P G+ GP
Sbjct: 150 PEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGP-----------------GKPAGP 192
Query: 122 PIYAAPSNLKRASALLNLYEA-----------PEELLADGEGGGTDEGIYDVPLLGPEAP 170
A L ++ALLN + A P LL + I P +G AP
Sbjct: 193 ---GAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAP 249
Query: 171 PSPEPPGALASHDQDTLAQLLARSPPPPHRP----RLPSAESLSRRPLPALPVPEAPS-- 224
P+P P A+ A A PPPP P R P + PA+P P A
Sbjct: 250 PAPAAPSPPAA---PAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNG 306
Query: 225 ----PSPVPSPAPGRKGSIQDRPLPPPPPRLPGYG 255
+P P+PA G + +P P P G
Sbjct: 307 GSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPG 341
Score = 45.4 bits (106), Expect = 1e-04
Identities = 60/240 (25%), Positives = 80/240 (33%), Gaps = 40/240 (16%)
Query: 11 PPPARPCPTSGP----PAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPS 66
P PA P P + P PA PP P + R G A P A P A S
Sbjct: 250 PAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHP-AGPPTAAPAVPPPAAAQNGGS 308
Query: 67 SGPYDCPASFSHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAA 126
+G PA + V+ QP P P P + E P + AA
Sbjct: 309 AGAAPAPAPAAGGPAGVSGQP-----GPGAAAAAPAPGVKAE---------SPKRVVQAA 354
Query: 127 PSNLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDT 186
P + +A P A G T +G P P PP+P P L
Sbjct: 355 PPAAQTLAA-----SGPASTAASMVIGPTMQGALPSPAAVP--PPAPGTPTGLPKGAAGA 407
Query: 187 LAQLLARSPPPPHRPRLPSAESLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQDRPLPP 246
+ Q L+R+P + + P + P P P P+ +IQ+ LPP
Sbjct: 408 VTQSLSRTP-------TATTSGIRATLTPTVLAPRLPQPPQNPT-------NIQNFQLPP 453
Score = 45.1 bits (105), Expect = 1e-04
Identities = 57/204 (27%), Positives = 72/204 (35%), Gaps = 19/204 (9%)
Query: 65 PSSGPYDCPASFSHPLTRVAPQPPGEDDAPYD-VPLTPKPPA-ELEPDLEWEGGR-EPGP 121
P + P PA + P PQ PG VP P PPA +L P E G P P
Sbjct: 83 PGAAPEPPPAGRARP-GGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVP 141
Query: 122 PIYAAPSNLKRASALLNLYEAPEELLAD-GEGGGTDEGIYDVPLLGPEAPPSP-EPPGAL 179
A + + A A P L A G G G P GP P P +P G
Sbjct: 142 AAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPG--------PGPGPGPGPGPGKPAGPG 193
Query: 180 ASHDQDTLAQLLARSPPPPHRPRLPSAESLSRRPLPALPVPEAPSPSPVPSPAPGRKGSI 239
A+ + A LL H P+ ++ P LP+P+ +P V P +
Sbjct: 194 AAQTLNGSAALLNS-----HHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAA 248
Query: 240 QDRPLPPPPPRLPGYGGPKVEGDP 263
P P PP P P P
Sbjct: 249 PPAPAAPSPPAAPAPAAPAAAPPP 272
Score = 42.0 bits (97), Expect = 0.001
Identities = 64/243 (26%), Positives = 85/243 (34%), Gaps = 45/243 (18%)
Query: 12 PPARPCPTSGPPAGP------------------CPPSPDLIYKIPRASGTQLAAPRDALE 53
P P P G PAGP P+ L+ P A L P+ A
Sbjct: 178 PGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAAL---LPLPKPA-- 232
Query: 54 VYDVPPTALRVPSSGPYDCPASFSHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEW 113
P T ++ P P+ A+ P AP PP AP P PP L
Sbjct: 233 ---APGTVIQTP---PFVGAAA---PPAPAAPSPPAAP-APAAPAAAPPPPPPAPATLAR 282
Query: 114 EGGREPGPPIYAAPSNLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSP 173
G GPP AAP+ A+A A GG G+ P GP A +
Sbjct: 283 PPGHPAGPPT-AAPAVPPPAAAQNGGSAGAAPAPAPAAGGPA--GVSGQP--GPGAAAAA 337
Query: 174 EPPGALASHDQDTLAQLLARSPPPPHRPRLPSAESLSRRPLPALPVPEA--PSPSPVPSP 231
PG A + + ++ PP + S + + + P + PSP+ VP P
Sbjct: 338 PAPGVKAESPKRVV-----QAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPP 392
Query: 232 APG 234
APG
Sbjct: 393 APG 395
Score = 37.0 bits (84), Expect = 0.038
Identities = 49/192 (25%), Positives = 66/192 (34%), Gaps = 23/192 (11%)
Query: 186 TLAQLLARSPPPPHR--PRLPSAESLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQDRP 243
+L LA S H PR P + + L V +P+ + PA +G+ P
Sbjct: 28 SLESQLAASAAHHHHLAPRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAP 87
Query: 244 LPPPPPRL-PGYGGPKVEGDPEGR-------------EMEDDPAGHHNEYEGIPMAEEYD 289
PPP R PG GGP+ G P R ++ P G +P A
Sbjct: 88 EPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAV- 146
Query: 290 YVHLKGMDKAQG--SRPPDQACTGDPELPERGMPAPQEALSPGEPLVVSTGDLQLLYFYA 347
G + A ++P A P G P P PG G Q L A
Sbjct: 147 ---AAGPEPAPAGPAKPAGPAALAARAGPGPG-PGPGPGPGPGPGKPAGPGAAQTLNGSA 202
Query: 348 GQCQSHYSALQA 359
SH++A A
Sbjct: 203 ALLNSHHAAAPA 214
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 62.8 bits (151), Expect = 7e-10
Identities = 91/325 (28%), Positives = 104/325 (32%), Gaps = 77/325 (23%)
Query: 12 PPARPC----PTSGPPAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPP------TA 61
PP RP P S PP P P P R S PR PP TA
Sbjct: 170 PPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTA 229
Query: 62 LRVPSSGPYDCPASFSHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGP 121
L S P S S P + P PP A D P P PP P + E P P
Sbjct: 230 LGGGSIR--QSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREA--VPPP 285
Query: 122 PIYAAPSNLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALAS 181
P P N K + P P +APP P PP
Sbjct: 286 P----PQNNKPP-----VPSTPR------------------PSASSQAPPPPPPP----- 313
Query: 182 HDQDTLAQLLARSPPPPHRPRLPSAESLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQD 241
+R PPP P + R P L + S S P P+PGR G
Sbjct: 314 ----------SRPGPPPLPPSSSGNDETPRLPQRNLSL----SSSTPPLPSPGRSG---- 355
Query: 242 RPLPPPPPRLPGYGGPKVEGDPEGRE--MEDDPAGHHNEYEGIPMAEEYDYVHLKGMDKA 299
PLPPPP P P DP GR + P N + G+D
Sbjct: 356 -PLPPPPSERP----PPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSP 410
Query: 300 Q-GSRPPDQACTGDPELPERGMPAP 323
+ G RPP P+ P G P P
Sbjct: 411 RSGPRPP-----LPPDRPSAGAPPP 430
Score = 50.1 bits (118), Expect = 4e-06
Identities = 77/282 (27%), Positives = 95/282 (33%), Gaps = 70/282 (24%)
Query: 10 VPPPARPCPT---SGP--------PAGPCPPSPDLIYK-IPRASGTQLA------APRDA 51
+PPP P S P P GP PSP P GT L +P +
Sbjct: 183 IPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSS 242
Query: 52 LEVYDVPPTALRVPSSGPYDCPASFSHPL-------TRVAPQPPGEDDAPYDVPLTPKPP 104
+ P PS D P P+ P PP +++ P VP TP+P
Sbjct: 243 SSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKP-PVPSTPRPS 301
Query: 105 AELEPDLEWEGGREPGPPIYAAPSN-----LKRASALLNLYEAPEELLADGEGGGTDEGI 159
A + PGPP S+ + L+L + L + G G
Sbjct: 302 ASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSG------ 355
Query: 160 YDVPLLGP--EAPPSP--EPPGALASHDQDTLAQLLARSPPPPHRPRLPSAESLSRRPLP 215
PL P E PP P +PPG PPP R + R LP
Sbjct: 356 ---PLPPPPSERPPPPVRDPPGRSGP----------LPPPPPVSR------NGSTSRALP 396
Query: 216 ALPVPEAPSPSPVPSPAPGRKGSIQDRPLPPPPPRLPGYGGP 257
A P+ PS S V SP G P PP PP P G P
Sbjct: 397 A--TPQLPSRSGVDSPRSG--------PRPPLPPDRPSAGAP 428
Score = 45.4 bits (106), Expect = 1e-04
Identities = 60/203 (29%), Positives = 74/203 (36%), Gaps = 40/203 (19%)
Query: 59 PTALRVPSSGPYDCPASFSHPLTRVAPQPPG----EDDAPYDVPLTPKP----PAELEPD 110
P VPS G P R+ P P D P VP TP+P P
Sbjct: 147 PGRFPVPSPGHRSGPPEPQR--NRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSP 204
Query: 111 LEWEGGREPGPPIYAAPSNLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAP 170
G R+P P P R +AL GGG+ I PL +P
Sbjct: 205 PVPGGPRQPSPGPTPPPFPGNRGTAL---------------GGGS---IRQSPL-SSSSP 245
Query: 171 PSPEPPGALASHDQDTLAQLLARSPPPPHRPRLPSAESLSRRPLPALPVPEAPSPSPVPS 230
S PP T ++ L PPPP P + + S+ R +P P P + PVPS
Sbjct: 246 FSNRPPLP------PTPSRALDDKPPPPPPP-VGNRPSIHREAVP--PPPPQNNKPPVPS 296
Query: 231 PAPGRKGSIQDRPLPPPPPRLPG 253
R + P PPPPP PG
Sbjct: 297 TP--RPSASSQAPPPPPPPSRPG 317
Score = 42.7 bits (99), Expect = 7e-04
Identities = 52/190 (27%), Positives = 70/190 (36%), Gaps = 33/190 (17%)
Query: 158 GIYDVPLLGPEA-PPSPE-----PPGALASHDQDTLAQLLARSPPPPHRPRLPSAESLSR 211
G + VP G + PP P+ PP D++ PP P PR P S
Sbjct: 148 GRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIP------PPVPSTPR-PIQSSPHN 200
Query: 212 RPLPALPV-PEAPSPSPVPSPAPGRK------GSIQDRPLPPPPPRLPGYGGPKVEGDPE 264
R P +P P PSP P P P PG + GSI+ PL P P + P
Sbjct: 201 RGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSS---PFSNRPPLPPTP- 256
Query: 265 GREMEDDPAGHHNEYEGIPMAEEYDYVHLKGM--DKAQGSRPPDQACTGDPELPERGMPA 322
R ++D P P +H + + Q ++PP + T P + P
Sbjct: 257 SRALDDKPP------PPPPPVGNRPSIHREAVPPPPPQNNKPPVPS-TPRPSASSQAPPP 309
Query: 323 PQEALSPGEP 332
P PG P
Sbjct: 310 PPPPSRPGPP 319
Score = 30.8 bits (68), Expect = 2.8
Identities = 39/137 (28%), Positives = 44/137 (32%), Gaps = 34/137 (24%)
Query: 150 GEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQLLARSPPPPHRPRLPSAESL 209
G GGG G P LG + A+ D D+ PP P P S
Sbjct: 85 GGGGGGSFGGGGPPGLGGLFQAGMPKLRSTANRDNDS------GGSRPPLLP--PGGRST 136
Query: 210 SRRPLPALPVPEAPSPSPVPSPA-------PGRKGSIQDRP--------LPPPPPRLP-- 252
S +P P P PVPSP P R RP +PPP P P
Sbjct: 137 SAKPFSP---PSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRP 193
Query: 253 ------GYGGPKVEGDP 263
G P V G P
Sbjct: 194 IQSSPHNRGSPPVPGGP 210
Score = 29.6 bits (65), Expect = 6.1
Identities = 29/119 (24%), Positives = 41/119 (34%), Gaps = 37/119 (31%)
Query: 1 MAIATSVYVVPPPARPCPTSGPP--------------AGPCPPSPDLIYKIPRASGTQLA 46
+++++S +P P R P PP +GP PP P + R T A
Sbjct: 339 LSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPP----PVSRNGSTSRA 394
Query: 47 APRDALEVYDVPPTALRVPSSGPYDCPASFSHPLTRVAPQPPGEDDAPYDVPLTPKPPA 105
P ++PS D P R P+PP D P P PP+
Sbjct: 395 L-----------PATPQLPSRSGVDSP--------RSGPRPPLPPDRPSAGAPPPPPPS 434
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 62.8 bits (151), Expect = 7e-10
Identities = 91/325 (28%), Positives = 104/325 (32%), Gaps = 77/325 (23%)
Query: 12 PPARPC----PTSGPPAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPP------TA 61
PP RP P S PP P P P R S PR PP TA
Sbjct: 170 PPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTA 229
Query: 62 LRVPSSGPYDCPASFSHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGP 121
L S P S S P + P PP A D P P PP P + E P P
Sbjct: 230 LGGGSIR--QSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREA--VPPP 285
Query: 122 PIYAAPSNLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALAS 181
P P N K + P P +APP P PP
Sbjct: 286 P----PQNNKPP-----VPSTPR------------------PSASSQAPPPPPPP----- 313
Query: 182 HDQDTLAQLLARSPPPPHRPRLPSAESLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQD 241
+R PPP P + R P L + S S P P+PGR G
Sbjct: 314 ----------SRPGPPPLPPSSSGNDETPRLPQRNLSL----SSSTPPLPSPGRSG---- 355
Query: 242 RPLPPPPPRLPGYGGPKVEGDPEGRE--MEDDPAGHHNEYEGIPMAEEYDYVHLKGMDKA 299
PLPPPP P P DP GR + P N + G+D
Sbjct: 356 -PLPPPPSERP----PPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSP 410
Query: 300 Q-GSRPPDQACTGDPELPERGMPAP 323
+ G RPP P+ P G P P
Sbjct: 411 RSGPRPP-----LPPDRPSAGAPPP 430
Score = 50.1 bits (118), Expect = 4e-06
Identities = 77/282 (27%), Positives = 95/282 (33%), Gaps = 70/282 (24%)
Query: 10 VPPPARPCPT---SGP--------PAGPCPPSPDLIYK-IPRASGTQLA------APRDA 51
+PPP P S P P GP PSP P GT L +P +
Sbjct: 183 IPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSS 242
Query: 52 LEVYDVPPTALRVPSSGPYDCPASFSHPL-------TRVAPQPPGEDDAPYDVPLTPKPP 104
+ P PS D P P+ P PP +++ P VP TP+P
Sbjct: 243 SSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKP-PVPSTPRPS 301
Query: 105 AELEPDLEWEGGREPGPPIYAAPSN-----LKRASALLNLYEAPEELLADGEGGGTDEGI 159
A + PGPP S+ + L+L + L + G G
Sbjct: 302 ASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSG------ 355
Query: 160 YDVPLLGP--EAPPSP--EPPGALASHDQDTLAQLLARSPPPPHRPRLPSAESLSRRPLP 215
PL P E PP P +PPG PPP R + R LP
Sbjct: 356 ---PLPPPPSERPPPPVRDPPGRSGP----------LPPPPPVSR------NGSTSRALP 396
Query: 216 ALPVPEAPSPSPVPSPAPGRKGSIQDRPLPPPPPRLPGYGGP 257
A P+ PS S V SP G P PP PP P G P
Sbjct: 397 A--TPQLPSRSGVDSPRSG--------PRPPLPPDRPSAGAP 428
Score = 45.4 bits (106), Expect = 1e-04
Identities = 60/203 (29%), Positives = 74/203 (36%), Gaps = 40/203 (19%)
Query: 59 PTALRVPSSGPYDCPASFSHPLTRVAPQPPG----EDDAPYDVPLTPKP----PAELEPD 110
P VPS G P R+ P P D P VP TP+P P
Sbjct: 147 PGRFPVPSPGHRSGPPEPQR--NRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSP 204
Query: 111 LEWEGGREPGPPIYAAPSNLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAP 170
G R+P P P R +AL GGG+ I PL +P
Sbjct: 205 PVPGGPRQPSPGPTPPPFPGNRGTAL---------------GGGS---IRQSPL-SSSSP 245
Query: 171 PSPEPPGALASHDQDTLAQLLARSPPPPHRPRLPSAESLSRRPLPALPVPEAPSPSPVPS 230
S PP T ++ L PPPP P + + S+ R +P P P + PVPS
Sbjct: 246 FSNRPPLP------PTPSRALDDKPPPPPPP-VGNRPSIHREAVP--PPPPQNNKPPVPS 296
Query: 231 PAPGRKGSIQDRPLPPPPPRLPG 253
R + P PPPPP PG
Sbjct: 297 TP--RPSASSQAPPPPPPPSRPG 317
Score = 42.7 bits (99), Expect = 7e-04
Identities = 52/190 (27%), Positives = 70/190 (36%), Gaps = 33/190 (17%)
Query: 158 GIYDVPLLGPEA-PPSPE-----PPGALASHDQDTLAQLLARSPPPPHRPRLPSAESLSR 211
G + VP G + PP P+ PP D++ PP P PR P S
Sbjct: 148 GRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIP------PPVPSTPR-PIQSSPHN 200
Query: 212 RPLPALPV-PEAPSPSPVPSPAPGRK------GSIQDRPLPPPPPRLPGYGGPKVEGDPE 264
R P +P P PSP P P P PG + GSI+ PL P P + P
Sbjct: 201 RGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSS---PFSNRPPLPPTP- 256
Query: 265 GREMEDDPAGHHNEYEGIPMAEEYDYVHLKGM--DKAQGSRPPDQACTGDPELPERGMPA 322
R ++D P P +H + + Q ++PP + T P + P
Sbjct: 257 SRALDDKPP------PPPPPVGNRPSIHREAVPPPPPQNNKPPVPS-TPRPSASSQAPPP 309
Query: 323 PQEALSPGEP 332
P PG P
Sbjct: 310 PPPPSRPGPP 319
Score = 30.8 bits (68), Expect = 2.8
Identities = 39/137 (28%), Positives = 44/137 (32%), Gaps = 34/137 (24%)
Query: 150 GEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQLLARSPPPPHRPRLPSAESL 209
G GGG G P LG + A+ D D+ PP P P S
Sbjct: 85 GGGGGGSFGGGGPPGLGGLFQAGMPKLRSTANRDNDS------GGSRPPLLP--PGGRST 136
Query: 210 SRRPLPALPVPEAPSPSPVPSPA-------PGRKGSIQDRP--------LPPPPPRLP-- 252
S +P P P PVPSP P R RP +PPP P P
Sbjct: 137 SAKPFSP---PSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRP 193
Query: 253 ------GYGGPKVEGDP 263
G P V G P
Sbjct: 194 IQSSPHNRGSPPVPGGP 210
Score = 29.6 bits (65), Expect = 6.1
Identities = 29/119 (24%), Positives = 41/119 (34%), Gaps = 37/119 (31%)
Query: 1 MAIATSVYVVPPPARPCPTSGPP--------------AGPCPPSPDLIYKIPRASGTQLA 46
+++++S +P P R P PP +GP PP P + R T A
Sbjct: 339 LSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPP----PVSRNGSTSRA 394
Query: 47 APRDALEVYDVPPTALRVPSSGPYDCPASFSHPLTRVAPQPPGEDDAPYDVPLTPKPPA 105
P ++PS D P R P+PP D P P PP+
Sbjct: 395 L-----------PATPQLPSRSGVDSP--------RSGPRPPLPPDRPSAGAPPPPPPS 434
>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
Length = 2217
Score = 62.0 bits (149), Expect = 1e-09
Identities = 108/417 (25%), Positives = 150/417 (35%), Gaps = 83/417 (19%)
Query: 9 VVPPPARPCPTS-GPPAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPP-------- 59
V+PPP+ P PT G PA P P L P Q+ AP+ + + VPP
Sbjct: 709 VLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLP---QVLAPQPVVPLQPVPPHLPPYLAP 765
Query: 60 -TALRVPSS-GPYDCPASFSHPLTRVAPQPPGEDDAPYDVPLTPK------PPAELEPDL 111
+ + P+ P P + PL +V PQ P P P+TP PPA PDL
Sbjct: 766 ASQVGAPAQLKPLQMPQAPLQPLAQVPPQMP---PIPVVPPITPLAGIDGLPPAL--PDL 820
Query: 112 EWEGGREPGPPIYAAPSNLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPL--LGPEA 169
PP Y +P+ + + A +P L + +P + P A
Sbjct: 821 PTATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNA 880
Query: 170 PPS-----PEPPGALASHDQDTLAQLLARS--------------PPPPH----------- 199
P + PPG A +AQL + PP PH
Sbjct: 881 PATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPP 940
Query: 200 RPRLPSAESLSRRPLPALPVPEAPSPSPVPSPAPGRKGS--IQDRPLPPPPPRLPGYGGP 257
+P LP +L P P LP P PV P P R + +P+ PP P LP P
Sbjct: 941 QPALPPQPTLP--PQPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQ--P 996
Query: 258 KVEGDPEGREMEDDPAGHHNEYEGIPMAEEYDYVHLKGMDKAQGSRPPDQACTGDPELPE 317
+ PE P H + P A + L P A ++P
Sbjct: 997 ALPVRPE-------PLQPHLPEQAAPAATPGSQILL--------GHPAPYAVDVAAQVPT 1041
Query: 318 RGMPAPQEALSPGEPLVVSTGDLQLLYFYAGQCQSHYSALQAAVAALMSSTQANQPP 374
+P P LSP P V+ +LL Q S + + A+V ++ + T PP
Sbjct: 1042 VPVP-PAAVLSPPLPEVLLPAAPELL----PQFPSSLATVSASVQSVPTQTATLLPP 1093
Score = 50.4 bits (119), Expect = 3e-06
Identities = 83/335 (24%), Positives = 121/335 (36%), Gaps = 60/335 (17%)
Query: 17 CPTSGPPAGPCPPS--PDLIYKIPRASGTQLAAPRDALEVYDVPP---TALRVPSSGPYD 71
CP + PA P S P + +P + A +D L + P + + +GP +
Sbjct: 1316 CPVAEHPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSN 1375
Query: 72 CPASFSHPLTRVAPQPPGEDDAPYD--VPLTPKPPAELEPDLEWEGGREPGPPIYAAPSN 129
P + PL AP P P D P T P GG PG P S
Sbjct: 1376 PPGAPPAPL---APSSPPVTALPQDGAAPATSTMPEPASGTASQAGG--PGTP-QGLTSE 1429
Query: 130 LKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQ 189
L+ + L +EAP + PL+ AP +P P A T
Sbjct: 1430 LETSQPLAETHEAPLAVQ---------------PLVVGLAPCTPAPEAA------STRDA 1468
Query: 190 LLARSPPPPHRPRLPSAESLSRRPLPALPVPEAPSP--------SPVPSP-----APGRK 236
R P PP P PS S + +P P P P+ S +PSP P +
Sbjct: 1469 SAPREPLPPPAPE-PSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLPSPPLGPTVPPQP 1527
Query: 237 GSIQDRPLPPPPPRLPGYGGPKVEGDPEGREM---EDDPAGHHNEYEGIPMAEEYDYVHL 293
S + PPPR+ D + R + E P + + + + D+
Sbjct: 1528 PSALESDGEGPPPRVGFVDSTIKSLDEKLRTLLYQEHVPTSSASAGTPVEVGDR-DFT-- 1584
Query: 294 KGMDKAQGSRPPDQACTGDPELPERGMPAPQEALS 328
++ +G +P + C GD LP P P+EA+S
Sbjct: 1585 --LEPLRGDQPRSEVCGGDLALP----PVPKEAVS 1613
Score = 41.2 bits (95), Expect = 0.002
Identities = 74/297 (24%), Positives = 106/297 (35%), Gaps = 61/297 (20%)
Query: 2 AIATSVYVVPPPARPC-PTSGPPAGPC--PPSPDLIYKIPRASGTQLAAPRDALEVYDVP 58
A++ V P +P P + P P PPSP + RA+ Q A P +P
Sbjct: 896 ALSIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPT----LP 951
Query: 59 PTALRVPSSGPYDCPASFSHPLTRVAPQP--PGEDDAPYDVPLTPKPPAELEPDLEWEGG 116
P + P P P P PQP P + P L P+P + P+
Sbjct: 952 PQPVLPPQ--PTLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPE-----P 1004
Query: 117 REPGPPIYAAPSNLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPP 176
+P P AAP+ + LL + AP Y V + + P P PP
Sbjct: 1005 LQPHLPEQAAPAATPGSQILLG-HPAP----------------YAVDVAA-QVPTVPVPP 1046
Query: 177 GALASHDQDTLAQLLARSPPPPHRPRLPSAESLSRRPLPALPVPEAPSPSPVPSPAPGRK 236
A+ S L ++L + P P+ PS+ + + ++P A P P PG
Sbjct: 1047 AAVLS---PPLPEVLLPAAPEL-LPQFPSSLATVSASVQSVPTQTATLLPPANPPLPGGP 1102
Query: 237 G-------------------SIQDRPLPPPPPRLPGYGGPKVEGDPEGREMEDDPAG 274
G + QD+P P P YGG V G+E+ D G
Sbjct: 1103 GIASPCPTVQLTVEPVQEEQASQDKP-PGLPQSCESYGGSDV---TSGKELSDSCEG 1155
Score = 36.2 bits (82), Expect = 0.066
Identities = 50/195 (25%), Positives = 73/195 (37%), Gaps = 37/195 (18%)
Query: 85 PQPPGEDDAPYDV--PLTPKPPAELEPDLEWEGGREPGPPIYAAPSNLKRASALLNLYEA 142
P P E +A + P P L D ++ G+ G +Y+ + +++ L +L +A
Sbjct: 586 PPEPEEPEADQHLLPPTLPTSATSLASDSTFDSGQ--GSTVYSDSQSSQQSVMLGSLADA 643
Query: 143 PEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQ-LLARSPPPPHRP 201
+ + P+ E P P+ +L ++ Q T A L S P P P
Sbjct: 644 APS---------PAQCVCSPPV--SEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACP 692
Query: 202 RLPSAESLSRRPL----PALPVPEAPSPSPVPSPAPGRKGS---IQDRPLP--------- 245
PS + P P LP P P P+ PAP + Q PLP
Sbjct: 693 --PSLQQHFPDPAMSFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVV 750
Query: 246 ---PPPPRLPGYGGP 257
P PP LP Y P
Sbjct: 751 PLQPVPPHLPPYLAP 765
Score = 29.6 bits (65), Expect = 6.1
Identities = 49/190 (25%), Positives = 60/190 (31%), Gaps = 35/190 (18%)
Query: 149 DGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQLLARSPPPPHRPRLPSAES 208
DG+GG D P + PG A + A P P R ES
Sbjct: 2 DGDGGRRD------------VPGTLMEPGRGAGPAGMAEPRAKAARPGPQRFLRRSVVES 49
Query: 209 LSRRPLPALPVPEAPSPSPVPSPAPGR-----------KGSIQDRPLPPPPPRL---PGY 254
P P L EAP P P P P R + RP P P L PG
Sbjct: 50 DQEEP-PGLEAAEAPGPQP-PQPLQRRVLLLCKTRRLIAERARGRPAAPAPAALVAQPGA 107
Query: 255 GGPKVEGDPE---GREMEDDPAGHHNEY----EGIPMAEEYDYVHLKGMDKAQGSRPPDQ 307
G + PE +E DP E +G P E V + A+ P +
Sbjct: 108 PGAPADAGPEPVGTQEPGPDPIAAAVETAPAPDGGPREEAAATVRKEDEGAAEAKPEPGR 167
Query: 308 ACTGDPELPE 317
+PE E
Sbjct: 168 TRRDEPEEEE 177
>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
sapiens]
Length = 483
Score = 62.0 bits (149), Expect = 1e-09
Identities = 77/273 (28%), Positives = 93/273 (34%), Gaps = 83/273 (30%)
Query: 13 PARPCPTSGPPAGPCPPSPDLIYKIPRASG--TQLAAPRDALEVYDVPPTALRVPSSGPY 70
P RP + PP P PP P L +P +S T L +P L ++P A VP + P
Sbjct: 166 PPRPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPP- 224
Query: 71 DCPASFSHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAAPSNL 130
P PP P P PPA + D +
Sbjct: 225 --------------PPPPPPPPTP-----PPLPPASVLSD-----------------KAV 248
Query: 131 KRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQL 190
K A L+L P L PLL P P + A + D
Sbjct: 249 KPQLAPLHLPPIPPPL----------------PLLPPCGYPGLKAEPASPAQD------- 285
Query: 191 LARSPPPPHRPRLPSAESLSRRPLPALPVP------EAPSPSPVPSP---APGRKGSIQD 241
A+ PP P P P A R LPA P+P E P P P SP AP +K Q
Sbjct: 286 -AQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQA 344
Query: 242 RPLPPPPP-----------RLPGYGGPKVEGDP 263
P PP PP PG GG K+ P
Sbjct: 345 LPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPP 377
Score = 43.9 bits (102), Expect = 3e-04
Identities = 78/318 (24%), Positives = 97/318 (30%), Gaps = 82/318 (25%)
Query: 9 VVPPPARPCPTSGPPAG-PCPPSPDLIYKIPRASGTQLAAP--RDALEVYDVPPTALRVP 65
V PPP P P PP G P PP P S + A P R AL T LR
Sbjct: 3 VPPPPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLR-- 60
Query: 66 SSGPYDCPASFSHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYA 125
+ R APQ E EGG +
Sbjct: 61 ---------KVTQINDRSAPQ------------------IESSKGTNKEGGGSANTRGAS 93
Query: 126 APSNLKR--ASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHD 183
P L A L A + +A G+ G P L + P P A
Sbjct: 94 TPPTLGDLFAGGFPVLRPAGQRDVAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLG 153
Query: 184 QDTLAQLLARS-----------------PPPPHRPRLPSAESLS---------------- 210
+ A AR+ PPPP P LPS+ +
Sbjct: 154 NTSEAHGAARTAPPRPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLP 213
Query: 211 --RRPLPALPVPEAPSPSPVPSPAP-----------GRKGSIQDRPLPPPPPRLP--GYG 255
P+P P P P P P P P P + + P+PPP P LP GY
Sbjct: 214 VVAPPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYP 273
Query: 256 GPKVEGDPEGREMEDDPA 273
G K E ++ ++ PA
Sbjct: 274 GLKAEPASPAQDAQEPPA 291
Score = 38.1 bits (87), Expect = 0.017
Identities = 54/209 (25%), Positives = 69/209 (33%), Gaps = 39/209 (18%)
Query: 10 VPPPARPCPTSGPPAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGP 69
+P A P P + PP P PP P +P AS A + L +PP +P P
Sbjct: 212 LPVVAPPVPCAPPP--PPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPP 269
Query: 70 YDCPASFSHPLTRVAPQPPGEDDAPYDVPLTPKPP-AELEPDLEWEGGREPG-------- 120
+P + P P +D P P PP A P PG
Sbjct: 270 ------CGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETP 323
Query: 121 PPI------YAAPSNLKRASALLNLYEAP--------EELLADGEGGGTDEGIYDVPLLG 166
PP+ + AP A AL P + G GGG L
Sbjct: 324 PPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGG--------KLNP 375
Query: 167 PEAPPSPEPPGALASHDQDTLAQLLARSP 195
P APP+ P L+S Q A + P
Sbjct: 376 PPAPPARSPTTELSSKSQQATAWTPTQQP 404
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 61.6 bits (148), Expect = 1e-09
Identities = 89/341 (26%), Positives = 116/341 (34%), Gaps = 42/341 (12%)
Query: 12 PPARPCPTSGPP-AGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGPY 70
PP PTS PP A P P+ + P L+ P LE + P P S P
Sbjct: 451 PPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRP---LEESPLSPPPEESPLSPP- 506
Query: 71 DCPASFSHPLTRVAPQPPGEDDAP---YDVPLTPKPPAE-LEPDLEWEGGREPGPPIYAA 126
P S +P P E+ P + PL+P P A L P E P + +
Sbjct: 507 --PESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTS 564
Query: 127 P----SNLKRASALLNLYEAPEE--LLADGEGGGTDEGIYDVPLLGP--EAPPSPEPPGA 178
P S L + PEE + E + PL P E+P SP P +
Sbjct: 565 PPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEAS 624
Query: 179 LASHDQDTLAQLLARSPPPPHRPRLPSAESLSRRPLPAL----PVPEAPSPSPVPSPAPG 234
S + SPPP P P E PLP + P PE SP P +P
Sbjct: 625 RLSPPPEDSPM----SPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPT 680
Query: 235 RKGSIQDRPLPPP------PPRLPGYGGPKVEGDPEGREMEDDPAGHHNEYEGIPMAEEY 288
R PPP PP P E +E+ P +P+ EE
Sbjct: 681 SPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPL--------LPLPEE- 731
Query: 289 DYVHLKGMDKAQGSRPPDQACTGDPELPERGMPAPQEALSP 329
+ + RP + + PE P A + LSP
Sbjct: 732 PQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSP 772
Score = 52.8 bits (125), Expect = 7e-07
Identities = 69/277 (24%), Positives = 104/277 (37%), Gaps = 48/277 (17%)
Query: 60 TALRVPSSGPYDCPASFSHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGREP 119
T+++ GP C A PL + Q + +AP + + PP E P
Sbjct: 402 TSMQPKEPGPLQCEAK---PLGKAGVQLEPQLEAPLNEEMPLLPPPEESP---------L 449
Query: 120 GPPIYAAPSNLKRASALLNLYEAPEELLADG--EGGGTDEGIYDVPLLGPEAPPSPEPPG 177
PP +P++ ++ L+ PEEL A E + + PL +PP E P
Sbjct: 450 SPPPEESPTSPPPEASRLS--PPPEELPASPLPEALHLSRPLEESPL----SPPPEESP- 502
Query: 178 ALASHDQDTLAQLLARSPPPPHRPRLPSAESLSRRPLPALPVPEAPSPSPVPSPAPGRKG 237
SPPP P P ES P + P P +P P A
Sbjct: 503 ---------------LSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSP 547
Query: 238 SIQDRPLPPPPPRLPGYGGP---KVEGDPEGREMEDDPAGHHNEYEGIPMAEEYDYVHL- 293
++ PL PPP LP P ++ PE M P E PM+ + L
Sbjct: 548 PFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPP-------EESPMSPPPEASRLF 600
Query: 294 KGMDKAQGSRPPDQACTGDPELPERGMPAPQEA-LSP 329
+++ S PP+++ P R P P+++ +SP
Sbjct: 601 PPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSP 637
Score = 48.1 bits (113), Expect = 2e-05
Identities = 84/335 (25%), Positives = 115/335 (34%), Gaps = 81/335 (24%)
Query: 12 PPARPCPTSGPPA-GPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGPY 70
PP P S PP P P P+ P + L+ P P
Sbjct: 574 PPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPP--------------------PE 613
Query: 71 DCPASFSHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAAPSNL 130
+ P S +R++P P D P++P P E P P + S L
Sbjct: 614 ESPLSPPPEASRLSPPPE-------DSPMSPPPE---------ESPMSPPPEV----SRL 653
Query: 131 KRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGP--EAPPSPEPPGA-LASHDQDTL 187
+ L PEE PL P E+P SP P + L+ +D+
Sbjct: 654 SPLPVVSRLSPPPEE----------------SPLSPPPEESPTSPPPEASRLSPPPEDS- 696
Query: 188 AQLLARSPPPPHRPRLPSAE-SLSRRPL---PALPVPEAP-----SPSPVPSPAPGRKGS 238
SPPP P P E SL PL P LP+PE P S P SP P
Sbjct: 697 ----PTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEP-- 750
Query: 239 IQDRPLPPPPPRLPGYGGPKVEGDPEGREMEDDPAGHH--NEYEGIPMAEEYDYVHLKGM 296
P P P P P + PE + P H + EG ++ + + +HL
Sbjct: 751 -HLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQ 809
Query: 297 DKAQGSRP-PDQAC-TGDPELPERGMPAPQEALSP 329
+ P P++ C + PE + + LSP
Sbjct: 810 TEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSP 844
Score = 48.1 bits (113), Expect = 2e-05
Identities = 92/351 (26%), Positives = 125/351 (35%), Gaps = 70/351 (19%)
Query: 22 PPAG--PCPPSP-DLIYKIPRASGTQLAA--PRDALEVYDVPPTALRVPSS-GPYDCP-- 73
PPAG P P SP +L K+P Q+ + P Y + P P + PY P
Sbjct: 2145 PPAGSVPGPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTG 2204
Query: 74 ASFSHPLTRVAPQP----PGE-----DDAPYDVPLTPKPPAELE---------PDLEWEG 115
A P+ + +P PGE P P TP P + P+ G
Sbjct: 2205 APAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVG 2264
Query: 116 GREPGPPIYAAPSNLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLG-PEAPPSPE 174
G + P+ + P + AL E +E L G Y P LG ++P S
Sbjct: 2265 GGKASEPLLSPPPFGESRKAL----EVKKEEL------GASSPSYGPPNLGFVDSPSSGT 2314
Query: 175 PPGALASHDQDTLAQLLARSPPPPHRPRL-PSAESLSRRPLPALPVPEAPSPSPVPSPAP 233
G L D ++P P ++ P + L RP P +A +PSP P
Sbjct: 2315 HLGGLELKTPDVF-----KAPLTPRASQVEPQSPGLGLRPQEPPPA-QALAPSPPSHPDI 2368
Query: 234 GRKGSIQD---------RPLPPPP-------PR-LPGYGGPKVEGDPEGREMEDDPAGHH 276
R GS D RP PPPP PR LP +V P+ + P
Sbjct: 2369 FRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPR 2428
Query: 277 NEYEGIPMAEEY---DYVHLKGMDKAQGSRPPDQACTGDPELPERGMPAPQ 324
P++ E V + SRPP + + DP P P PQ
Sbjct: 2429 ------PLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQ 2473
Score = 47.4 bits (111), Expect = 3e-05
Identities = 54/185 (29%), Positives = 73/185 (39%), Gaps = 38/185 (20%)
Query: 95 YDVPLTPKPPAEL--EP---DLEWEGGREPG---PPIYAAPSNLKRASALLNLYEAPEEL 146
Y+V L P+ PA EP + E GG+E G P LK+ A+L Y +L
Sbjct: 4815 YEV-LFPESPARAGTEPKKGEAEGPGGKEKGLEGKSPDTGPDWLKQFDAVLPGYTLKSQL 4873
Query: 147 LADGEGGGTDEGIYDVPLLGPEAPPSPEPPGA------LASHDQDTLAQLLARSPPPPHR 200
D+ L + P+PEPP +++ D L+ P PP
Sbjct: 4874 --------------DILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPS 4919
Query: 201 PRLPSAESLSRRPL---PALPVPEAPSPSPVPSPAPGRKGSIQDRPLPPP------PPRL 251
P PS S PL P P+ E P PSP+P + + R PP PPRL
Sbjct: 4920 PLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARPPEEGEDSRPPRL 4979
Query: 252 PGYGG 256
+ G
Sbjct: 4980 KKWKG 4984
Score = 45.8 bits (107), Expect = 8e-05
Identities = 77/281 (27%), Positives = 99/281 (35%), Gaps = 50/281 (17%)
Query: 12 PPARPCPTSGPPAGP--CPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGP 69
PP PTS PP PP D P P D+L + + L P
Sbjct: 673 PPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEP 732
Query: 70 YDCPASFSHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAAPS- 128
CP S P P+ P P + L+P+ EP L + P + A P
Sbjct: 733 QLCPRS-EGPHLSPRPEEPHLSPRPEEPHLSPQAE---EPHLS---PQPEEPCLCAVPEE 785
Query: 129 -NLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDTL 187
+L + +L PEEL + T+E P P PE P Q
Sbjct: 786 PHLSPQAEGPHLSPQPEELHLSPQ---TEE---------PHLSPVPEEP---CLSPQPEE 830
Query: 188 AQLLARSPPPPHRPRLPSAESLS---RRPLPALPVPEAPSPSPVPSPAPGRKGSIQDRPL 244
+ L +S P PR P LS +P P P PE P P PAP ++ PL
Sbjct: 831 SHLSPQSEEPCLSPR-PEESHLSPELEKP-PLSPRPEKPPEEPGQCPAP------EELPL 882
Query: 245 PPPP-----------PRLPGYGGPKVEGDPEGREMEDDPAG 274
PPP P L G P + PE E+ P+G
Sbjct: 883 FPPPGEPSLSPLLGEPALSEPGEPPLSPLPE--ELPLSPSG 921
Score = 45.4 bits (106), Expect = 1e-04
Identities = 65/250 (26%), Positives = 91/250 (36%), Gaps = 52/250 (20%)
Query: 8 YVVPPPARPCPTSGPPAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSS 67
++ P P PC + P P + PR + L+ + PP +
Sbjct: 814 HLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEK------PPLS------ 861
Query: 68 GPYDCPASFSHPLTRVAPQPPGEDDAPYDVPLTPKPPAE--LEPDLEWEGGREPG-PPIY 124
P P+ PG+ AP ++PL P PP E L P L EPG PP+
Sbjct: 862 -----------PRPEKPPEEPGQCPAPEELPLFP-PPGEPSLSPLLGEPALSEPGEPPLS 909
Query: 125 AAPSNLKRASA---LLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGAL-- 179
P L + + L+ P + L P++ APP+ P G L
Sbjct: 910 PLPEELPLSPSGEPSLSPQLMPPDPLPPPLS----------PIITAAAPPALSPLGELEY 959
Query: 180 ---ASHDQDTLAQLLARSPPPPHRPRLPSAESLSRRPLPALPVPEAPSPSPVPSPAPGRK 236
A D D + L A P P P A P+P + +P +P SPV +P
Sbjct: 960 PFGAKGDSDPESPLAAPILETPISPP-PEANCTDPEPVPPMILPPSPG-SPVGPASP--- 1014
Query: 237 GSIQDRPLPP 246
I PLPP
Sbjct: 1015 --ILMEPLPP 1022
Score = 43.9 bits (102), Expect = 3e-04
Identities = 70/276 (25%), Positives = 95/276 (34%), Gaps = 65/276 (23%)
Query: 12 PPARPCPTSGPPA-GPCPPSPDLIYKIPRASGTQLAAPRDALEVY--------DVPPTAL 62
PP P S PP P P P++ P ++L+ P + + PP A
Sbjct: 628 PPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEAS 687
Query: 63 RVPSSGPYDCPASFSHPLTRVAPQPPGEDDAPYDVPLTPKP--PAELEPDLEWEGGREPG 120
R+ S P D P S P +P P +D+ +PL P P EP L R G
Sbjct: 688 RL-SPPPEDSPTS---PPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQL---CPRSEG 740
Query: 121 PPIYAAPSNLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAP-----PSPEP 175
P + P +L PEE P L P+A P PE
Sbjct: 741 PHLSPRPEEP-------HLSPRPEE-----------------PHLSPQAEEPHLSPQPEE 776
Query: 176 PGALASHDQDTL---AQLLARSPPP-----------PHRPRLPSAESLSRRPLPALPVPE 221
P A ++ L A+ SP P PH +P LS +P + P+
Sbjct: 777 PCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQ 836
Query: 222 APSPSPVPSPAPGRKGSIQDR----PLPPPPPRLPG 253
+ P P P ++ P P PP PG
Sbjct: 837 SEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPG 872
Score = 35.4 bits (80), Expect = 0.11
Identities = 28/86 (32%), Positives = 36/86 (41%), Gaps = 11/86 (12%)
Query: 167 PEAPPS-PEPPGALASHDQDTLAQLLARSPPPPHRPRLPSAESLSRRPLPALPVPEAPSP 225
P+ PP P PPGAL++ L + PPP P+ P S P LP P
Sbjct: 4283 PQGPPRLPAPPGALSTGP--VLGPV--HPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPP 4338
Query: 226 SPVPSPAPGRKGSIQDRPLPPPPPRL 251
+ +P P Q L PPP R+
Sbjct: 4339 THPGTPKP------QGPTLEPPPGRV 4358
Score = 35.0 bits (79), Expect = 0.15
Identities = 30/84 (35%), Positives = 36/84 (42%), Gaps = 12/84 (14%)
Query: 189 QLLARSPPPPHRPRLPSAE-SLSRRPL--PALPVP------EAPSPSPVPSPAPGRKGSI 239
Q L P P PRLP+ +LS P+ P P P E PS +PSP+
Sbjct: 4275 QELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEA 4334
Query: 240 QDRPLPPPPPRLPGYGGPKVEGDP 263
Q LPP P P GP +E P
Sbjct: 4335 Q---LPPTHPGTPKPQGPTLEPPP 4355
Score = 35.0 bits (79), Expect = 0.15
Identities = 34/107 (31%), Positives = 41/107 (38%), Gaps = 13/107 (12%)
Query: 176 PGALASHDQDTLAQLLARSP---PPPHRPRLPSAESLSRRPLPALPVPEAPSPSP---VP 229
PG D L+ L SP PP + +L R L A P PE PSP P P
Sbjct: 4865 PGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSA-PPPEEPSPPPSPLAP 4923
Query: 230 SPAPGRKGSIQDRPL-----PPPPPRLPGYGGPK-VEGDPEGREMED 270
SPA + + P PP P LP P+ P R E+
Sbjct: 4924 SPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARPPEE 4970
Score = 34.7 bits (78), Expect = 0.19
Identities = 49/187 (26%), Positives = 64/187 (34%), Gaps = 33/187 (17%)
Query: 12 PPARP------CPTSGPPAGPCPPSPDLIYKIPRASGTQLAA----------PRDALEVY 55
PP+RP P PP P P++ +K + T L A P L
Sbjct: 2453 PPSRPQSRDPFAPLHKPPR---PQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAK 2509
Query: 56 ---DVPPTALRVPSSGPYDCPASFSHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLE 112
PP +R P +G + S P+ PQ GE VP PP +
Sbjct: 2510 VPSGQPPNFVRSPGTGAFVGTPS---PMRFTFPQAVGEPSLKPPVPQPGLPPPH---GIN 2563
Query: 113 WEGGREPGPPIYAAPSNLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPS 172
G PGP + P + A N + + L G T E PL P P
Sbjct: 2564 SHFG--PGPTL-GKPQSTNYTVATGNFHPSGSPL--GPSSGSTGESYGLSPLRPPSVLPP 2618
Query: 173 PEPPGAL 179
P P G+L
Sbjct: 2619 PAPDGSL 2625
Score = 34.3 bits (77), Expect = 0.25
Identities = 67/275 (24%), Positives = 91/275 (33%), Gaps = 51/275 (18%)
Query: 12 PPARPCPTSGP--PAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTA-----LRV 64
PP P P P P+G SP L+ P L P + PP L
Sbjct: 906 PPLSPLPEELPLSPSGEPSLSPQLMPPDP------LPPPLSPIITAAAPPALSPLGELEY 959
Query: 65 P--SSGPYDCPASFSHPL--TRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGREPG 120
P + G D + + P+ T ++P P P VP PP+ P P
Sbjct: 960 PFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPV-------GPA 1012
Query: 121 PPIYAAPSNLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALA 180
PI P + S LL P+ + P L P P G +
Sbjct: 1013 SPILMEPLP-PQCSPLLQHSLVPQN---------SPPSQCSPPALPLSVPSPLSPIGKVV 1062
Query: 181 SHDQDTLAQLLARSPPPPHRPRLPSAESLSRRPLPALPVPEAPSPSPVPSPAPGR---KG 237
+ A+L P P+ E + PLP+ P P PSPAP G
Sbjct: 1063 GVSDE--AELHEMETEKVSEPECPALEPSATSPLPS---PMGDLSCPAPSPAPALDDFSG 1117
Query: 238 SIQD-RPL--------PPPPPRLPGYGGPKVEGDP 263
+D PL P P + PG +++G P
Sbjct: 1118 LGEDTAPLDGIDAPGSQPEPGQTPGSLASELKGSP 1152
Score = 29.6 bits (65), Expect = 6.1
Identities = 28/103 (27%), Positives = 36/103 (34%), Gaps = 15/103 (14%)
Query: 23 PAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGPYDCPASF-SHPLT 81
PA P Y + QL+AP PP P S PAS + PL
Sbjct: 4884 PAPEPPTQHSYTYNVSNLDVRQLSAP---------PPEEPSPPPSPLAPSPASPPTEPLV 4934
Query: 82 RVAPQPPGEDDAPYDVPL-----TPKPPAELEPDLEWEGGREP 119
+ +P E P +PL + +P P E E R P
Sbjct: 4935 ELPTEPLAEPPVPSPLPLASSPESARPKPRARPPEEGEDSRPP 4977
Score = 29.6 bits (65), Expect = 6.1
Identities = 26/85 (30%), Positives = 28/85 (32%), Gaps = 18/85 (21%)
Query: 11 PPPARPCPTSGPPAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALR-VPSSGP 69
PPP P P P A P P SP P + L P A VPS P
Sbjct: 4909 PPPEEPSPPPSPLA-PSPASP----------------PTEPLVELPTEPLAEPPVPSPLP 4951
Query: 70 YDCPASFSHPLTRVAPQPPGEDDAP 94
+ P R P GED P
Sbjct: 4952 LASSPESARPKPRARPPEEGEDSRP 4976
>gi|47132519 Ras association and pleckstrin homology domains 1
isoform 1 [Homo sapiens]
Length = 1250
Score = 61.2 bits (147), Expect = 2e-09
Identities = 70/252 (27%), Positives = 97/252 (38%), Gaps = 50/252 (19%)
Query: 11 PPPARPCPTSGPPAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGPY 70
PPP P P PP P P + IP + T+ AP + PPT P P
Sbjct: 763 PPPPPPIPAPLPPQAPPKP----LVTIPAPTSTKTVAP---VVTQAAPPTP--TPPVPPA 813
Query: 71 DCPASFSHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAAPSNL 130
+F P + + P PP P P PP L P + + P P+ PS +
Sbjct: 814 KKQPAF--PASYIPPSPP--------TPPVPVPPPTL-PKQQSFCAKPPPSPLSPVPSVV 862
Query: 131 KRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQL 190
K+ + + + P T + PL A +P+ P A+ + + + +
Sbjct: 863 KQ---IASQFPPPP----------TPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSI 909
Query: 191 LARSP--PPPHRPRLPSAESLSRRPLPALPVPEAP-------SPSPVPSPAPGRKGSIQD 241
SP PPP P SL P P PVP P SP+P S +PG+K S
Sbjct: 910 PVPSPDFPPP-----PPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTS 964
Query: 242 RP---LPPPPPR 250
P PPP P+
Sbjct: 965 SPGGKKPPPTPQ 976
Score = 55.1 bits (131), Expect = 1e-07
Identities = 68/290 (23%), Positives = 97/290 (33%), Gaps = 52/290 (17%)
Query: 11 PPPARPCPTSGPPAGPCPPSPD-----------------LIYKIPRAS---GTQLAAPRD 50
PPP P P PP P PP P I ++ AS G P
Sbjct: 630 PPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTP 689
Query: 51 ALEVYD-------VPPTALRVPSSGPYDCPASFSHPLTRVAPQPPGEDDAPYDVPLTPKP 103
+ VPP + VP P P + + ++ P P + P P
Sbjct: 690 PVMQSQSVKPQILVPPNGV-VPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLK 748
Query: 104 PAELEPDLEWEGGREPGPPIYAAPSNLKRASALLNLYEAPEELLADGEGGGTDEGIYDVP 163
+++ + P PP AP + L AP P
Sbjct: 749 IHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVA------------P 796
Query: 164 LLGPEAPPSPEPPGALASHDQDTLAQLLARSPPPPH----RPRLPSAESLSRRPLPALPV 219
++ APP+P PP A A + SPP P P LP +S +P P+
Sbjct: 797 VVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPS--- 853
Query: 220 PEAPSPSPVPS-----PAPGRKGSIQDRPLPPPPPRLPGYGGPKVEGDPE 264
P +P PS V P P +++ +PL P P + P V+ P+
Sbjct: 854 PLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPK 903
Score = 53.1 bits (126), Expect = 5e-07
Identities = 67/278 (24%), Positives = 90/278 (32%), Gaps = 58/278 (20%)
Query: 11 PPPARPCPTSGPPAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGPY 70
PPP P PT G P+P S Q +AP L+++ V P + P
Sbjct: 712 PPPPPPPPTPGSAMAQLKPAPCA------PSLPQFSAPPPPLKIHQVQHITQVAPPTPPP 765
Query: 71 DCPASFSHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAAPSNL 130
P AP PP P P + P + P PP+ A
Sbjct: 766 PPPIP--------APLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPA---- 813
Query: 131 KRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSP----EPPGALASHDQDT 186
K+ A Y P VP+ P P +PP + S
Sbjct: 814 KKQPAFPASYIPPSPPTPP------------VPVPPPTLPKQQSFCAKPPPSPLSPVPSV 861
Query: 187 LAQLLARSPPPPHRPRLPSAESLSRRPLPALPVPEAPS---------------PSPVPSP 231
+ Q+ ++ PPPP P + ES +P+PA P++P PSP P
Sbjct: 862 VKQIASQFPPPPTPPAM---ESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPP 918
Query: 232 APGRKGSI------QDRPLPPPPPRLPGYGGPKVEGDP 263
P + P PPPPP P G P
Sbjct: 919 PPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSP 956
Score = 48.9 bits (115), Expect = 1e-05
Identities = 71/271 (26%), Positives = 100/271 (36%), Gaps = 69/271 (25%)
Query: 10 VPPPARPCPTSGPPAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGP 69
+PPP P P PP P PP P L + ++G+ AAP ++ T R+ ++
Sbjct: 628 LPPPPPPPPPPPPP--PPPPPPPLPSQSAPSAGS--AAP-----MFVKYSTITRLQNASQ 678
Query: 70 YDCPASFSHPLT------RVAPQ---PPGEDDAPYDVPLTPKPPAELEPDLEWEGGREPG 120
+ A F P V PQ PP VP P PP P
Sbjct: 679 HS-GALFKPPTPPVMQSQSVKPQILVPPNGV-----VPPPPPPP--------------PP 718
Query: 121 PPIYAAPSNLKRASALLNL--YEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGA 178
P +A + LK A +L + AP L I+ V + APP+P PP
Sbjct: 719 PTPGSAMAQLKPAPCAPSLPQFSAPPPPLK----------IHQVQHITQVAPPTPPPPPP 768
Query: 179 L-----------------ASHDQDTLAQLLARSPPPPHRPRLPSAESLSRRPLPALPVPE 221
+ A T+A ++ ++ PP P +P A+ + PA +P
Sbjct: 769 IPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAK--KQPAFPASYIPP 826
Query: 222 APSPSPVPSPAPGRKGSIQDRPLPPPPPRLP 252
+P PVP P P PPP P P
Sbjct: 827 SPPTPPVPVPPPTLPKQQSFCAKPPPSPLSP 857
Score = 46.2 bits (108), Expect = 6e-05
Identities = 63/262 (24%), Positives = 85/262 (32%), Gaps = 55/262 (20%)
Query: 42 GTQLAAPRDA-LEVYDVPPTALRVPSSGPYDCPASFSHPLTRVAPQPPGEDDAPYDVPLT 100
GTQL A +E + P T+L VP P P T P PP P P
Sbjct: 584 GTQLEESSKARMESMNRPYTSL-VPPLSPQP---KIVTPYTASQPSPPLPPPPPPPPPPP 639
Query: 101 PKPPAELEP----DLEWEGGREPGPPIYAAPSNLKRASALLN-LYEAPEELLADGEGGGT 155
P PP P G P Y+ + L+ AS L++ P + +
Sbjct: 640 PPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKP 699
Query: 156 DEGIYDVPLLGPEAPPSP------------------------EPPGALASHDQDTLAQLL 191
+ ++ P PP P PP L H + Q+
Sbjct: 700 QILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVA 759
Query: 192 ARSPPPPHRPRLPSAESLSRRPLPALPVP-----------EAPSPSPVPSPAPGRK---- 236
+PPPP P +PL +P P +A P+P P P +K
Sbjct: 760 PPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAF 819
Query: 237 ------GSIQDRPLPPPPPRLP 252
S P+P PPP LP
Sbjct: 820 PASYIPPSPPTPPVPVPPPTLP 841
Score = 39.3 bits (90), Expect = 0.008
Identities = 22/63 (34%), Positives = 28/63 (44%), Gaps = 14/63 (22%)
Query: 195 PPPPHRPRLPSAESLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQDRPLPPPPPRLPGY 254
PP +P++ + + S+ P P LP P P P P P P PPPPP LP
Sbjct: 607 PPLSPQPKIVTPYTASQ-PSPPLPPPPPPPPPPPPPP-------------PPPPPPLPSQ 652
Query: 255 GGP 257
P
Sbjct: 653 SAP 655
Score = 38.5 bits (88), Expect = 0.013
Identities = 69/305 (22%), Positives = 91/305 (29%), Gaps = 76/305 (24%)
Query: 11 PPPARPCP------------TSGPPAGPCPPSPDLIYKIPRASGTQLAAPR----DALEV 54
PP A P P TS P PP+P I +SG + P+ D+L
Sbjct: 943 PPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVS 1002
Query: 55 YDVPPTALRVPSSGPYDCPASFSHP----LTRVA-------------------------- 84
PP PS PA+ P L+ V
Sbjct: 1003 KFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVV 1062
Query: 85 --PQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAAPSNLKRASALLNLYEA 142
P PP + D P P T P +E + G P + P + + +
Sbjct: 1063 EFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAV-VNPQPQQWSKMSVKKAPP 1121
Query: 143 PEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQLLARSPPPPHRPR 202
P + T I + P + P P P + S LA L R
Sbjct: 1122 PTRPKRNDSTRLTQAEISEQPTMATVVPQVPTSPKSSLSVQPGFLADLNRTL----QRKS 1177
Query: 203 LPSAESLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQDRPLPPPPPRL------PGYGG 256
+ SLS R A P ++ D LPPPPP L GYGG
Sbjct: 1178 ITRHGSLSSRMSRAEPT-----------------ATMDDMALPPPPPELLSDQQKAGYGG 1220
Query: 257 PKVEG 261
+ G
Sbjct: 1221 SHISG 1225
>gi|150417989 cyclin K isoform 1 [Homo sapiens]
Length = 580
Score = 60.8 bits (146), Expect = 2e-09
Identities = 70/260 (26%), Positives = 92/260 (35%), Gaps = 52/260 (20%)
Query: 11 PPPARP-CPTSGPPAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGP 69
PPP P T+ PP P P PD K P A+ A P ++ D+P + P+
Sbjct: 351 PPPKIPKIETTHPPLPPAHPPPDR--KPPLAAALGEAEPPGPVDATDLPKVQIPPPA--- 405
Query: 70 YDCPASFSHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAAPSN 129
HP P P P+ P P PP+ + G + S
Sbjct: 406 --------HPAPVHQPPP-----LPHRPP--PPPPSSYMTGMSTTSSYMSGEGYQSLQSM 450
Query: 130 LKRAS----ALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQD 185
+K AL Y P L Y + P PP P PP AS
Sbjct: 451 MKTEGPSYGALPPAYGPPAHLP------------YHPHVYPPNPPPPPVPPPP-ASFPPP 497
Query: 186 TLAQLLARSPPPPHR---------PRLPSAESLSRRPLPALPVPEAPSPSPVPSPAPGRK 236
+ PPPP PRLP ++ P P L +P P+ P P+ PG +
Sbjct: 498 AIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLP--PASYPPPAVPPGGQ 555
Query: 237 GSIQDRPLPPPPPRLPGYGG 256
+ P P PPP +P GG
Sbjct: 556 PPV---PPPIPPPGMPPVGG 572
Score = 46.6 bits (109), Expect = 5e-05
Identities = 64/268 (23%), Positives = 94/268 (35%), Gaps = 37/268 (13%)
Query: 13 PARPCPTSGPPAGPCPPSPDLIYKIPR-ASGTQLAAPRDALEVYDVPPTALRVPSSGPYD 71
P +P P P PSP PR + +P++ + + PP ++P
Sbjct: 307 PQQPAQQQQPAQQPKKPSPQP--SSPRQVKRAVVVSPKEENKAAEPPPP--KIPKIETTH 362
Query: 72 CPASFSHPLTRVAPQPP---GEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAAPS 128
P +HP P GE + P V T P ++ P +P PP+ P
Sbjct: 363 PPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQP-PPLPHRPP 421
Query: 129 NLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDTLA 188
+S + + + +G + P G PP+ PP L H
Sbjct: 422 PPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGA-LPPAYGPPAHLPYHPH---- 476
Query: 189 QLLARSPPPPHRPRLPSAESLSRRPLPALPVPEAPSPSPVPS-------PAPGRKGSIQD 241
+ +PPPP P P++ P PA+P P P P P+ P P +
Sbjct: 477 -VYPPNPPPPPVPPPPASF-----PPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAV 530
Query: 242 RPLPPP----------PPRLPGYGGPKV 259
P PPP PP +P G P V
Sbjct: 531 PPHPPPGLGLPPASYPPPAVPPGGQPPV 558
Score = 37.4 bits (85), Expect = 0.029
Identities = 59/271 (21%), Positives = 86/271 (31%), Gaps = 61/271 (22%)
Query: 22 PPAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGPYDCPASFSHPLT 81
P P P P ++ ++ +Q + P + P + P+ P
Sbjct: 277 PSLQPTPQVP----QVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQP-----------K 321
Query: 82 RVAPQPPGEDDAPYDVPLTPK-------PPAELEPDLEWEGGREPGPPIYAAPSNLKRAS 134
+ +PQP V ++PK PP P +E P PP + P +
Sbjct: 322 KPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIETT--HPPLPPAHPPPDRKPPLA 379
Query: 135 ALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAP----------PSPEPPGALASHDQ 184
A L E P G TD +P AP P P PP + +
Sbjct: 380 AALGEAEPP------GPVDATDLPKVQIPPPAHPAPVHQPPPLPHRPPPPPPSSYMTGMS 433
Query: 185 DTLA----------QLLARSPPPPHRPRLPSAESLSRRPLPALPVPEAPSPSPVPSPAPG 234
T + Q + ++ P + P+ + P P P P PVP P
Sbjct: 434 TTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPAS 493
Query: 235 RKGSIQDRPLPPP--PPRLPGYGGPKVEGDP 263
PPP PP PGY P +P
Sbjct: 494 ---------FPPPAIPPPTPGYPPPPPTYNP 515
Score = 33.5 bits (75), Expect = 0.42
Identities = 27/104 (25%), Positives = 38/104 (36%), Gaps = 5/104 (4%)
Query: 167 PEAPPSPEPPGALASHDQDTLAQLLARSPPPPHRPRLPSAESLSRRPLPALPVPEAPSPS 226
P+ S + S Q Q A+ P +P+ PS + S R + V +
Sbjct: 286 PQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEEN 345
Query: 227 PVPSPAPGRKGSIQDR--PLP---PPPPRLPGYGGPKVEGDPEG 265
P P + I+ PLP PPP R P E +P G
Sbjct: 346 KAAEPPPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPG 389
Score = 32.7 bits (73), Expect = 0.72
Identities = 31/102 (30%), Positives = 37/102 (36%), Gaps = 25/102 (24%)
Query: 9 VVPPPAR------PCPTSGPPAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTAL 62
V PPPA P PT G P P +P+ PR T P PP L
Sbjct: 487 VPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPH--------PPPGL 538
Query: 63 RVPSSGPYDCPASFSHPLTRVAPQPPGEDDAPYDVPLTPKPP 104
+P PAS+ P A P G+ P +P PP
Sbjct: 539 GLP-------PASYPPP----AVPPGGQPPVPPPIPPPGMPP 569
Score = 32.3 bits (72), Expect = 0.95
Identities = 34/120 (28%), Positives = 41/120 (34%), Gaps = 30/120 (25%)
Query: 8 YVVPPPARPCPTSGPPAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSS 67
+V PP P P PPA PP+ IP PPT P
Sbjct: 476 HVYPPNPPPPPVPPPPASFPPPA------IP-------------------PPTPGYPPPP 510
Query: 68 GPYDCPASFSHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAAP 127
Y+ +F P R+ PP P+ P PPA P GG+ P PP P
Sbjct: 511 PTYN--PNFPPPPPRL---PPTHAVPPHPPPGLGLPPASYPPPAVPPGGQPPVPPPIPPP 565
>gi|54860079 nadrin isoform 1 [Homo sapiens]
Length = 881
Score = 60.5 bits (145), Expect = 3e-09
Identities = 72/275 (26%), Positives = 105/275 (38%), Gaps = 63/275 (22%)
Query: 16 PCPTSGPPAGPCPPSPDLIYKIPRASGTQLAA----PRDALEVYDVPPTALRVPSSGPYD 71
P P G P P P + P + +Q+A+ P+ A + + ++ P +
Sbjct: 569 PSPGDGSPPKPKDPVSAAV-PAPGRNNSQIASGQNQPQAAAGSHQL---SMGQPHNAAGP 624
Query: 72 CPASFSHPLTRVAPQPPGEDDAPYDVP--------------LTPKPPAELEPDLEWEGGR 117
P + + + AP PP + P P L+PKPP G+
Sbjct: 625 SPHTLRRAVKKPAPAPPKPGNPPPGHPGGQSSSGTSQHPPSLSPKPPTRSPSPPTQHTGQ 684
Query: 118 EPGPPIYAAPSNL---KRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPE 174
PG P +APS L +R S+ L+ +AP T PL+ + P S
Sbjct: 685 PPGQP--SAPSQLSAPRRYSSSLSPIQAPNHPPPQPPTQAT-------PLMHTK-PNSQG 734
Query: 175 PPGALASHDQDTLAQLLARSPPPPHRPRLPSAESLSRRPLPALPVPEA------------ 222
PP +A + L Q S PP P PS L ++ P+LP P+
Sbjct: 735 PPNPMALPSEHGLEQ---PSHTPPQTPTPPSTPPLGKQN-PSLPAPQTLAGGNPETAQPH 790
Query: 223 ----PSPSPVPSPAPGRKGSIQDRPLPPPPPRLPG 253
P P PVP P ++RP PPPP+ PG
Sbjct: 791 AGTLPRPRPVPKP--------RNRPSVPPPPQPPG 817
Score = 35.4 bits (80), Expect = 0.11
Identities = 52/222 (23%), Positives = 71/222 (31%), Gaps = 58/222 (26%)
Query: 11 PPPARPCP----TSGPPAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPS 66
PP P P T PP P PS QL+APR Y + ++ P+
Sbjct: 670 PPTRSPSPPTQHTGQPPGQPSAPS-------------QLSAPRR----YSSSLSPIQAPN 712
Query: 67 SGP-----------YDCPASFSHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEG 115
P + P S P P G + + P TP PP+ P L +
Sbjct: 713 HPPPQPPTQATPLMHTKPNSQGPPNPMALPSEHGLEQPSHTPPQTPTPPST--PPLGKQN 770
Query: 116 GREPGPPIYAAPSNLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEP 175
P P A N + A P + P P PP P+P
Sbjct: 771 PSLPAPQTLAG-GNPETAQPHAGTLPRPRPV--------------PKPRNRPSVPPPPQP 815
Query: 176 PGALASHDQD------TLAQLLARS---PPPPHRPRLPSAES 208
PG ++ D T ++++ S PHR P S
Sbjct: 816 PGVHSAGDSSLTNTAPTASKIVTDSNSRVSEPHRSIFPEMHS 857
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 59.7 bits (143), Expect = 6e-09
Identities = 93/344 (27%), Positives = 109/344 (31%), Gaps = 63/344 (18%)
Query: 2 AIATSVYVVPPPARPCPTSG---PPAGPCPPSPDLI--YKIPRASGTQLAAPRDALEVYD 56
A S + PP PC S P G PP P + +P T + P
Sbjct: 848 AFKNSCNIPSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEM 907
Query: 57 VPPTALRVPSSGPYDCPASFSHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEGG 116
+PP +P +G P PP A +PL P P A + P G
Sbjct: 908 LPPPPPPLPGAG---------------IPPPPPLPGAGI-LPLPPLPGAGIPPPPPLPGA 951
Query: 117 REPGPPIYAAPSNLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPP 176
P PP + + L P L G G PL G PP P P
Sbjct: 952 AIPPPPPLPG-AGIPLPPPLPGAGIPPPPPL---PGAGIPP---PPPLPGAGIPPPPPLP 1004
Query: 177 GALASHDQDTLAQLLARSPPPPHRPRLPSAESLSRRPLPALPVPEAP----SPSPVPSPA 232
GA PPPP LP A PLP +P P + P P P
Sbjct: 1005 GA-------------GIPPPPP----LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1047
Query: 233 PGRKGSIQDRPLP----PPPPRLPGYGGPKVEGDPEGREMEDDPAGHHNEYEGIPMAEEY 288
PG G PLP PPPP LPG G P P P GIP
Sbjct: 1048 PG-AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL----PGAGIPPPPPL 1102
Query: 289 DYVHLKGMDKAQGSRPPDQACTGDPELPERGMPAPQEALSPGEP 332
V + G+ P P LP G+P P G P
Sbjct: 1103 PGVGIPPPPPLPGAGIPP-----PPPLPGAGIPPPPPLPGAGIP 1141
Score = 55.1 bits (131), Expect = 1e-07
Identities = 82/270 (30%), Positives = 90/270 (33%), Gaps = 50/270 (18%)
Query: 12 PPARPCPTSGPPAGPCPPSPDL-IYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGPY 70
PP P P +G P P PP P I P G + P PP L P +G
Sbjct: 987 PPPPPLPGAGIP--PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL--PGAGIP 1042
Query: 71 DCPASFSHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEG-GREPGPPIYAAPSN 129
P PL PP P P P A + P G G P PP+ A
Sbjct: 1043 PPP-----PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA--G 1095
Query: 130 LKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQ 189
+ L + P L G G PL G PP P PGA
Sbjct: 1096 IPPPPPLPGVGIPPPPPLP---GAGIPP---PPPLPGAGIPPPPPLPGA----------- 1138
Query: 190 LLARSPPPPHRPR--------LPSAESLSRRPLPALPVPEAPS----PSPVPSPAPGRKG 237
PPPP PR LP A PLP +P P P P P PG G
Sbjct: 1139 ---GIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPG-VG 1194
Query: 238 SIQDRPLP----PPPPRLPGYGGPKVEGDP 263
PLP PPPP LPG G P P
Sbjct: 1195 IPPPPPLPGAGIPPPPPLPGMGIPPAPAPP 1224
Score = 52.4 bits (124), Expect = 9e-07
Identities = 81/270 (30%), Positives = 93/270 (34%), Gaps = 45/270 (16%)
Query: 9 VVPPPARPCPTSGPPAGPCPPSPDL-IYKIPRASGTQLAAPRDALEVYDVPPTALRVPSS 67
++PPP P P +G P P PP P I +P G + P PP L P +
Sbjct: 907 MLPPPPPPLPGAGIP--PPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPL--PGA 962
Query: 68 GPYDCPASFSHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEG-GREPGPPIYAA 126
G PL PP P P P A + P G G P PP+ A
Sbjct: 963 G-----IPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA 1017
Query: 127 ----PSNLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASH 182
P L A P L G G PL G PP P PGA
Sbjct: 1018 GIPPPPPLPGAGI-----PPPPPL----PGAGIPP---PPPLPGAGIPPPPPLPGA-GIP 1064
Query: 183 DQDTLAQLLARSPPP------PHRPRLPSAESLSRRPLPALPVPEAPSPSP---VPSPAP 233
L PPP P P LP A PLP + +P P P P +P P P
Sbjct: 1065 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPP-PLPGAGIPPPPP 1123
Query: 234 GRKGSIQDRP------LPPPPPRLPGYGGP 257
I P +PPPPP LP G P
Sbjct: 1124 LPGAGIPPPPPLPGAGIPPPPP-LPRVGIP 1152
Score = 45.8 bits (107), Expect = 8e-05
Identities = 71/252 (28%), Positives = 81/252 (32%), Gaps = 55/252 (21%)
Query: 12 PPARPCPTSGPPAGPCPPSPDL-IYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGPY 70
PP P P +G P P PP P I P G + P PP L P +G
Sbjct: 1031 PPPPPLPGAGIP--PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL--PGAGIP 1086
Query: 71 DCPASFSHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEG-GREPGPPIYAAPSN 129
P PL PP P P P A + P G G P PP+ A
Sbjct: 1087 PPP-----PLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP 1141
Query: 130 LKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQ 189
+ + P PL G PP P PGA
Sbjct: 1142 PPPPLPRVGIPPPP-------------------PLPGAGIPPPPPLPGA----------- 1171
Query: 190 LLARSPPPPHRPRLPSAESLSRRPLPALPVPEAP----SPSPVPSPAPGRKGSIQDRPLP 245
PPPP LP PLP + +P P + P P P PG I P P
Sbjct: 1172 --GIPPPPP----LPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGM--GIPPAPAP 1223
Query: 246 PPPPRLPGYGGP 257
P PP PG G P
Sbjct: 1224 PLPP--PGTGIP 1233
Score = 45.1 bits (105), Expect = 1e-04
Identities = 56/180 (31%), Positives = 65/180 (36%), Gaps = 42/180 (23%)
Query: 164 LLGP-----EAPPSPEPPGALASHDQDTLAQLLARSPPPPHRPRLPSAESLSRRPLPALP 218
LLGP EAP SP+ AL++ L + LA P P +P P LP
Sbjct: 253 LLGPSGGAGEAPGSPDTEQALSALSD--LPESLAAEPREPQQPPSPGG----------LP 300
Query: 219 VPEAPSPSPVPSPAPGRKGSIQDRPLPPPPPRLPGYGGPKVEG----DPEGRE--MEDDP 272
V EAPS P PA S P P P G P V G D EG E ED P
Sbjct: 301 VSEAPS-LPAAQPAAKDSPSSTAFPFPEAGPGEEAAGAP-VRGAGDTDEEGEEDAFEDAP 358
Query: 273 AGHHNEYEGIPMAEEYDYVHLKGMDKAQGSRPPDQACTGDPELPERGMPAPQEALSPGEP 332
G E + E+ Q +PE +G AP A PG P
Sbjct: 359 RGSPGEEWAPEVGED-----------------APQRLGEEPEEEAQGPDAPAAASLPGSP 401
Score = 30.0 bits (66), Expect = 4.7
Identities = 54/242 (22%), Positives = 79/242 (32%), Gaps = 62/242 (25%)
Query: 18 PTSGPPAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGPYDCPASFS 77
P+ G AG P SPD AL P +L P P+
Sbjct: 256 PSGG--AGEAPGSPDT---------------EQALSALSDLPESLAAEPREPQQPPSPGG 298
Query: 78 HPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAAPSNLKRASALL 137
P++ AP P A D P + P E GP AA + ++ A
Sbjct: 299 LPVSE-APSLPAAQPAAKDSPSSTAFPFP-----------EAGPGEEAAGAPVRGAG--- 343
Query: 138 NLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPE----PPGALASHDQDTLAQLLAR 193
D + G ++ D P P +PE P L ++ A+
Sbjct: 344 -----------DTDEEGEEDAFEDAPRGSPGEEWAPEVGEDAPQRLGEEPEEE-----AQ 387
Query: 194 SPPPPHRPRLPSAESLSRRPLPALPV----------PEAPSPSPVPSPAPGRKGSIQDRP 243
P P LP + + S+R P+ + SP+ PS +P + I+ RP
Sbjct: 388 GPDAPAAASLPGSPAPSQRCFKPYPLITPCYIKTTTRQLSSPNHSPSQSPNQSPRIKRRP 447
Query: 244 LP 245
P
Sbjct: 448 EP 449
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 59.3 bits (142), Expect = 7e-09
Identities = 64/233 (27%), Positives = 81/233 (34%), Gaps = 48/233 (20%)
Query: 58 PPTALRVPSSGPYDCPASFSHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGR 117
PP PS P P S S P P PP P +P P PPA+ E +
Sbjct: 404 PPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPP--LPSPPPPPAQEEQE------- 454
Query: 118 EPGPPIYAAPSNLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPG 177
E PP+ A + KR L + E A GT P PP P
Sbjct: 455 ESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPT-PTPSTATGGPPEDSPTV 513
Query: 178 A------LASHDQDTLAQLLARS---------------PPPPH-------RPRLPSAESL 209
A L + Q + + ARS P PP RP + ++ +
Sbjct: 514 APKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPV 573
Query: 210 SRRPLPALPVPEAPSPSPVPSPAPGRKGSIQDRP----------LPPPPPRLP 252
+ P P P AP+P P P P ++ SI P LPPPPP P
Sbjct: 574 PQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPP 626
Score = 55.1 bits (131), Expect = 1e-07
Identities = 79/301 (26%), Positives = 104/301 (34%), Gaps = 67/301 (22%)
Query: 11 PPPARPCPTSGPPAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGPY 70
PPP P P++ PP CPP P P S L +P PP S P
Sbjct: 413 PPPPLPPPSTSPPPPLCPPPP------PPVSPPPLPSPPP-------PPAQEEQEESPPP 459
Query: 71 DCPASFSHPLTR--VAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPI----- 123
PA+ S R + P E +A P PP P G E P +
Sbjct: 460 VVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPT-PSTATGGPPEDSPTVAPKST 518
Query: 124 --------YAAPSNLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPE---APPS 172
+ P R+S ++ + P + E + P+L P +PP
Sbjct: 519 TFLKNIRQFIMPVVSARSSRVI---KTPRRFM--DEDPPKPPKVEVSPVLRPPITTSPPV 573
Query: 173 PEPPGALASHDQDTLAQLLARSPPPPHRPRLPSAE--------------SLSRR---PLP 215
P+ P + S R+P PP P +P E SL+R P P
Sbjct: 574 PQEPAPVPSPP---------RAPTPPSTP-VPLPEKRRSILREPTFRWTSLTRELPPPPP 623
Query: 216 ALPVPEAPSPSPVPSPAPGRKGSIQDRPLPPPPPRLPGYGG---PKVEGDPEGREMEDDP 272
A P P APSP P P+ + R ++ P L Y P G PE E E P
Sbjct: 624 APPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPP 683
Query: 273 A 273
A
Sbjct: 684 A 684
Score = 46.6 bits (109), Expect = 5e-05
Identities = 58/190 (30%), Positives = 69/190 (36%), Gaps = 39/190 (20%)
Query: 86 QPPGEDDAPYD----VPLTPK---PPAELEPDLEWEGGREPGPPIYAAPSNLKRASALLN 138
+PPG +D P D VP P+ P L+P L + G P P AP + A +
Sbjct: 1813 EPPGGEDPPLDTDVLVPGAPERHSPIQNLDPPLRPDSGSAPPP----APRSFSGARIKVP 1868
Query: 139 LYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASH-----DQDTLAQLLAR 193
Y L GG G PL PSP P +L H D D A
Sbjct: 1869 NYSPSRRPL-----GGVSFG----PL------PSPGSPSSLTHHIPTVGDPDFPAPPRRS 1913
Query: 194 SPPPPHRPRLPSAESLSRRPLPALPVPEAPSPSPVPS---PAPGRKGSIQDRPLPPPPPR 250
P P PR P + S PL P P P+ V + P G P PPPP
Sbjct: 1914 RRPSPLAPRPPPSRWASP-PLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPSPPPPED 1972
Query: 251 LPGYGGPKVE 260
L GP E
Sbjct: 1973 L----GPDFE 1978
Score = 44.7 bits (104), Expect = 2e-04
Identities = 55/198 (27%), Positives = 71/198 (35%), Gaps = 35/198 (17%)
Query: 85 PQPPGEDDAPY-DVPLTPKPPAELEPDLEWEGGREPGPPIYAAPSNLKRASALLNLYEAP 143
P+PP + +P P+T PP EP R P PP P KR S L
Sbjct: 552 PKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRW 611
Query: 144 EELLADGEGGGTDEGIYDVPLLGPEAPP--SPEPPGALASHDQDTLAQLLARSPP-PPHR 200
L + +P P PP +P PP A A+ + LL R+P P
Sbjct: 612 TSLTRE------------LPPPPPAPPPPPAPSPPPAPATSSR---RPLLLRAPQFTPSE 656
Query: 201 PRLPSAESLSRRPLPALPVPEAPSPSPVPS------PAPGRKGSIQDRPLP--------P 246
L ES+ P L PEAP P P P+ P P G LP P
Sbjct: 657 AHLKIYESVLTP--PPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTP 714
Query: 247 PPPRLPGYGGPKVEGDPE 264
+ +G P + P+
Sbjct: 715 VKAEVSPHGAPALSNGPQ 732
Score = 42.0 bits (97), Expect = 0.001
Identities = 79/311 (25%), Positives = 107/311 (34%), Gaps = 77/311 (24%)
Query: 12 PPARPCPTSGPPAGPCPPSPDLIYKIPRASGTQ----------LAAPRDALEV------- 54
PP RP S PP P S I K+P S ++ L +P +
Sbjct: 1843 PPLRPDSGSAPPPAPRSFSGARI-KVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTV 1901
Query: 55 ----YDVPPTALRVPSS-GPYDCPASFSHPLTRVAPQ---PP------------GEDDAP 94
+ PP R PS P P+ ++ P + +PQ PP GE P
Sbjct: 1902 GDPDFPAPPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPP 1961
Query: 95 YDVPLTPKPPAELEPDLEWEGGREPGPPIYAAPSNLKRASALLNLYEAPEELLADGEGGG 154
P +P PP +L PD E E + AA +L A++LL EE++A G G
Sbjct: 1962 GPAP-SPPPPEDLGPDFE---DMEVVSGLSAA--DLDFAASLLGTEPFQEEIVAAGAMGS 2015
Query: 155 TDEG---------------------IYDVPLLGPEAPPSPEPPGALASHDQDTLAQLLAR 193
+ G + P L P A P L D T ++ A
Sbjct: 2016 SHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAV 2075
Query: 194 SPP-----PPHRPRLPSAESLSRRPLPALPVPEAPSP------SPVPSPAPGRKGSIQDR 242
P PP P + A L A P + PS + P G G ++
Sbjct: 2076 QQPRGQGTPPSGPGVVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGP-REE 2134
Query: 243 PLPPPPPRLPG 253
LPP PP G
Sbjct: 2135 SLPPAPPLANG 2145
Score = 37.7 bits (86), Expect = 0.023
Identities = 24/64 (37%), Positives = 28/64 (43%), Gaps = 6/64 (9%)
Query: 192 ARSPPPPHRPRLPSAES-----LSRRPLPALPVPEAP-SPSPVPSPAPGRKGSIQDRPLP 245
A+ PPPP P PS + P P P P P SP P+PSP P Q+ P
Sbjct: 399 AKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPP 458
Query: 246 PPPP 249
P P
Sbjct: 459 PVVP 462
Score = 34.7 bits (78), Expect = 0.19
Identities = 34/130 (26%), Positives = 45/130 (34%), Gaps = 8/130 (6%)
Query: 203 LPSAESLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQDRPLPPP---PPRLPGYGGPKV 259
+P+AE + P P APSP P P P P P PPP PP LP P
Sbjct: 391 MPAAEKEEAKLPPPPLTPPAPSPPP-PLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPA 449
Query: 260 EGDPEGREMEDDPAGHHNEYEGIPMAEEYDYVHLKGMDKAQGSRPPDQACTGDPELPERG 319
+ + E PA + P+ +G+ PP T P G
Sbjct: 450 QEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPP----TPTPSTATGG 505
Query: 320 MPAPQEALSP 329
P ++P
Sbjct: 506 PPEDSPTVAP 515
Score = 34.7 bits (78), Expect = 0.19
Identities = 57/220 (25%), Positives = 75/220 (34%), Gaps = 67/220 (30%)
Query: 88 PGEDDA-PYDVPLTPKPPAELEPDLEWEGGREPGPPIYAAPSNLKRASALLNLYEAPEEL 146
PG+ A P + L P PP G +P + A+P++ R A L
Sbjct: 2124 PGDGGAGPREESLPPAPPLA--------NGSQPSQGLTASPADPTRTFAWL--------- 2166
Query: 147 LADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHD--QDTLAQLLARS-------PPP 197
G V +L P+PEPP S + L Q+ + PPP
Sbjct: 2167 ----------PGAPGVRVLS--LGPAPEPPKPATSKIILVNKLGQVFVKMAGEGEPVPPP 2214
Query: 198 PHRPRLPSAES--------LSRRPL-PALPVPEAPSPSPVPSPAPGRKGSIQDRPLPPP- 247
+P LP S L PL LPV P+P P P P + P PP
Sbjct: 2215 VKQPPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTL-VLSSGPASPPR 2273
Query: 248 ---------------PPRLPGYGGPKVEGDPEGREMEDDP 272
PP P Y P++ D +G ED P
Sbjct: 2274 QAIRVKRVSTFSGRSPPAPPPYKAPRL--DEDGEASEDTP 2311
Score = 34.3 bits (77), Expect = 0.25
Identities = 29/96 (30%), Positives = 41/96 (42%), Gaps = 21/96 (21%)
Query: 11 PPPARPCPTSGPPAGPCPPSPDLIYKIPRASGTQLAAPRDA-LEVYDVPPTALRVPSSGP 69
PPP P P PPA PP+P + P P +A L++Y+ + L P G
Sbjct: 620 PPPPAPPP---PPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYE---SVLTPPPLGA 673
Query: 70 YDCPASFSHPLTRVAPQPPGEDDAPYDVPLTPKPPA 105
+ P P+PP DD+P + P+P A
Sbjct: 674 PEAP----------EPEPPPADDSPAE----PEPRA 695
Score = 32.0 bits (71), Expect = 1.2
Identities = 26/76 (34%), Positives = 30/76 (39%), Gaps = 11/76 (14%)
Query: 197 PPHRPRLPSAESLSRRPLPALPVPEA------PSPSPVPSPAPGRKGSIQDRPLPPPPPR 250
PP RP P RR A+ V EA P P P P + GS + + P P P
Sbjct: 223 PPGRPAGPC-----RRKQQAVVVAEAAVTIPKPEPPPPVVPVKHQTGSWKCKEGPGPGPG 277
Query: 251 LPGYGGPKVEGDPEGR 266
P GG G GR
Sbjct: 278 TPRRGGQSSRGGRGGR 293
Score = 31.2 bits (69), Expect = 2.1
Identities = 26/92 (28%), Positives = 36/92 (39%), Gaps = 6/92 (6%)
Query: 243 PLPPPPPRLPGYGGPKVE--GDPEGREMEDDPAGHHNEYEGIPMAEEYDYVHLKGMDKAQ 300
P PP P R G GGP+ E P G E +D + + YD +
Sbjct: 1040 PGPPGPRRGAGAGGPREEVVAHP-GPEEQDSLLQRKSARRCVKQRPSYDIFEDSDDSEPG 1098
Query: 301 GSRPPDQACTGDPELPERGMPAPQEALSPGEP 332
G P + + ELP +P P+E P +P
Sbjct: 1099 GPPAPRRRTPRENELP---LPEPEEQSRPRKP 1127
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 58.5 bits (140), Expect = 1e-08
Identities = 73/289 (25%), Positives = 103/289 (35%), Gaps = 48/289 (16%)
Query: 68 GPYDCPASFSHPLTRVAPQPPGEDDAPYDVPLTPKPPAE----LEPDLEWEGGR-----E 118
GP PA S LT+ Q PG P P T KPPA+ +P + G +
Sbjct: 327 GPAKPPAQPSG-LTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQ 385
Query: 119 PGPPIYAAPSNLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLL-------GPEAPP 171
PGP A P + + A + P + GT + + P L GP P
Sbjct: 386 PGPKALAQPPGVGKTPA-----QQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTP 440
Query: 172 SPEP-PGALASHDQD---TLAQLLARSPPPPHRPRLPSAESLSRRPLPALPVPEAPSPSP 227
+P PG + + T AQ + PP S+ P PA P P+ P P+
Sbjct: 441 VQQPGPGKIPAQQAGPGKTSAQQTGPTKPP------------SQLPGPAKPPPQQPGPAK 488
Query: 228 VPSPAPG-RKGSIQDRPLPPPPPRLPGYGGPKVEGDPEGREMEDDPAGHHNEYEGIPMAE 286
P PG K Q PPP+ PG P + + P P A+
Sbjct: 489 PPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPG------SAKPSAQ 542
Query: 287 EYDYVHLKGMDKAQGSRPPDQACTGDPELPERGMPAPQEALSPGEPLVV 335
+ Q ++P Q +G P P P+ ++ S G P +
Sbjct: 543 QPSPAKPSAQ---QSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTI 588
Score = 41.2 bits (95), Expect = 0.002
Identities = 53/208 (25%), Positives = 68/208 (32%), Gaps = 36/208 (17%)
Query: 71 DCPASFSHPLTRVAPQPPGEDDAPYDV------------PLTPKPPAELEPDLEWEGGRE 118
D P S L R AP P G A + V + PKP + + +
Sbjct: 2238 DYPEEISVSLDRTAP-PDGRASADHIVISLSDMASSIIESVVPKPEGPVADTVSTDLLIS 2296
Query: 119 PGPPIYAAPSNLKRASAL--LNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPP 176
P+ A L L Y +EL A+ E ++D P A P E
Sbjct: 2297 EKDPVKKAKKETGNGIILEVLEAYRDKKELEAERTKSSLSETVFDHPPSSVIALPMKEQL 2356
Query: 177 GALASHDQDTLAQLLARSPPP---------PHRPR---LPSAESLSRRPLPALPVPEAPS 224
+T Q S P P +PR S+ +S +P P P P P
Sbjct: 2357 STTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPP 2416
Query: 225 PSPVPSPAPGRKGSIQDRPLPPPPPRLP 252
P P P P P PLPPP P
Sbjct: 2417 PPPPPPPPP---------PLPPPTSPKP 2435
Score = 33.1 bits (74), Expect = 0.55
Identities = 57/234 (24%), Positives = 81/234 (34%), Gaps = 25/234 (10%)
Query: 11 PPPARPCPTSGPPAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTAL----RVPS 66
PPP P P PP P PP P L P S P+ L V TA V +
Sbjct: 2405 PPPPPPPPPPPPPPPPPPPPPPL---PPPTSPKPTILPKKKLTVASPVTTATPLFDAVTT 2461
Query: 67 SGPYDCPASFSHPLTRVA-----PQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGP 121
S P+TR+ P PP P + T +P P P P
Sbjct: 2462 LETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPP-------IAPKP 2514
Query: 122 PIYAAPSNLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALAS 181
I P+ ++ + +++ P L D L P +P SP +
Sbjct: 2515 VIPQLPTTTQKPT---DIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPR 2571
Query: 182 HDQD-TLAQLLARSPPPPHRPRLPSA-ESLSRRPLPALPVPEAPSPSPVPSPAP 233
+ T ++ P P P SA ++++ PL + P + S PV S P
Sbjct: 2572 FSKSLTETYVVITLPSEPGTPTDSSASQAITSWPLGS-PSKDLVSVEPVFSVVP 2624
Score = 31.6 bits (70), Expect = 1.6
Identities = 38/155 (24%), Positives = 57/155 (36%), Gaps = 31/155 (20%)
Query: 102 KPPAELEPDLEWEGGREPGPPIYAAPSNLKRASALLNLYEAPEELLADGEGGGTDEGIYD 161
KPP + +P + PG K S+ + PE++ + G G
Sbjct: 208 KPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISS-----QQPEKIKSQPPGTGK------ 256
Query: 162 VPLLGPEAPPSPE----PPGALASHDQDTLAQLLARSPPPPHRPRLPSAESLSRRPLPAL 217
P+ GP P + P AS Q A ++ +P LPS P+
Sbjct: 257 -PIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESV---KPSLPS---------PSK 303
Query: 218 PVPEAPSPSPVPSPAPGRKGSIQDRPLPPPPPRLP 252
P + P+P P+ PG + S +P P PP P
Sbjct: 304 PPIQQPTPGKPPAQQPGHEKS---QPGPAKPPAQP 335
Score = 29.3 bits (64), Expect = 8.0
Identities = 54/263 (20%), Positives = 84/263 (31%), Gaps = 25/263 (9%)
Query: 21 GPPAGPCPPSPDLIYKIPRASGTQLAA-----PRDALEVYDVPPTALRVPSSGPYDCPAS 75
G P P SP K + T + P+ D P + P P
Sbjct: 647 GGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPL 706
Query: 76 FSHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGREP-------GPPIYAAPS 128
P +P + D P PP E P + E + P P + +
Sbjct: 707 VKQPTLHGSPSAKAKQPPEADSLSKPAPPKE--PSVPSEQDKAPVADDKPKQPKMVKPTT 764
Query: 129 NLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGA---LASHDQD 185
+L +S+ + P + T PL A PS P ++ D
Sbjct: 765 DLVSSSSATTKPDIPSSKVQSQAEEKTTP-----PLKTDSAKPSQSFPPTGEKVSPFDSK 819
Query: 186 TLAQLLARSPPPPHRPRLPSAESLSRRPLPALPVPEAPSPSPVP-SPAPGRKGSIQDRPL 244
+ + + S H PS+ES ++ + + E P + SP P K + P
Sbjct: 820 AIPRPASDSKIISHPG--PSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPT 877
Query: 245 PPPPPRLPGYGGPKVEGDPEGRE 267
PP P G P + P+ +E
Sbjct: 878 PPGPRPTAGQTVPTPQQSPKPQE 900
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 58.5 bits (140), Expect = 1e-08
Identities = 73/289 (25%), Positives = 103/289 (35%), Gaps = 48/289 (16%)
Query: 68 GPYDCPASFSHPLTRVAPQPPGEDDAPYDVPLTPKPPAE----LEPDLEWEGGR-----E 118
GP PA S LT+ Q PG P P T KPPA+ +P + G +
Sbjct: 327 GPAKPPAQPSG-LTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQ 385
Query: 119 PGPPIYAAPSNLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLL-------GPEAPP 171
PGP A P + + A + P + GT + + P L GP P
Sbjct: 386 PGPKALAQPPGVGKTPA-----QQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTP 440
Query: 172 SPEP-PGALASHDQD---TLAQLLARSPPPPHRPRLPSAESLSRRPLPALPVPEAPSPSP 227
+P PG + + T AQ + PP S+ P PA P P+ P P+
Sbjct: 441 VQQPGPGKIPAQQAGPGKTSAQQTGPTKPP------------SQLPGPAKPPPQQPGPAK 488
Query: 228 VPSPAPG-RKGSIQDRPLPPPPPRLPGYGGPKVEGDPEGREMEDDPAGHHNEYEGIPMAE 286
P PG K Q PPP+ PG P + + P P A+
Sbjct: 489 PPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPG------SAKPSAQ 542
Query: 287 EYDYVHLKGMDKAQGSRPPDQACTGDPELPERGMPAPQEALSPGEPLVV 335
+ Q ++P Q +G P P P+ ++ S G P +
Sbjct: 543 QPSPAKPSAQ---QSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTI 588
Score = 41.2 bits (95), Expect = 0.002
Identities = 53/208 (25%), Positives = 68/208 (32%), Gaps = 36/208 (17%)
Query: 71 DCPASFSHPLTRVAPQPPGEDDAPYDV------------PLTPKPPAELEPDLEWEGGRE 118
D P S L R AP P G A + V + PKP + + +
Sbjct: 2238 DYPEEISVSLDRTAP-PDGRASADHIVISLSDMASSIIESVVPKPEGPVADTVSTDLLIS 2296
Query: 119 PGPPIYAAPSNLKRASAL--LNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPP 176
P+ A L L Y +EL A+ E ++D P A P E
Sbjct: 2297 EKDPVKKAKKETGNGIILEVLEAYRDKKELEAERTKSSLSETVFDHPPSSVIALPMKEQL 2356
Query: 177 GALASHDQDTLAQLLARSPPP---------PHRPR---LPSAESLSRRPLPALPVPEAPS 224
+T Q S P P +PR S+ +S +P P P P P
Sbjct: 2357 STTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPP 2416
Query: 225 PSPVPSPAPGRKGSIQDRPLPPPPPRLP 252
P P P P P PLPPP P
Sbjct: 2417 PPPPPPPPP---------PLPPPTSPKP 2435
Score = 33.1 bits (74), Expect = 0.55
Identities = 57/234 (24%), Positives = 81/234 (34%), Gaps = 25/234 (10%)
Query: 11 PPPARPCPTSGPPAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTAL----RVPS 66
PPP P P PP P PP P L P S P+ L V TA V +
Sbjct: 2405 PPPPPPPPPPPPPPPPPPPPPPL---PPPTSPKPTILPKKKLTVASPVTTATPLFDAVTT 2461
Query: 67 SGPYDCPASFSHPLTRVA-----PQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGP 121
S P+TR+ P PP P + T +P P P P
Sbjct: 2462 LETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPP-------IAPKP 2514
Query: 122 PIYAAPSNLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALAS 181
I P+ ++ + +++ P L D L P +P SP +
Sbjct: 2515 VIPQLPTTTQKPT---DIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPR 2571
Query: 182 HDQD-TLAQLLARSPPPPHRPRLPSA-ESLSRRPLPALPVPEAPSPSPVPSPAP 233
+ T ++ P P P SA ++++ PL + P + S PV S P
Sbjct: 2572 FSKSLTETYVVITLPSEPGTPTDSSASQAITSWPLGS-PSKDLVSVEPVFSVVP 2624
Score = 31.6 bits (70), Expect = 1.6
Identities = 38/155 (24%), Positives = 57/155 (36%), Gaps = 31/155 (20%)
Query: 102 KPPAELEPDLEWEGGREPGPPIYAAPSNLKRASALLNLYEAPEELLADGEGGGTDEGIYD 161
KPP + +P + PG K S+ + PE++ + G G
Sbjct: 208 KPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISS-----QQPEKIKSQPPGTGK------ 256
Query: 162 VPLLGPEAPPSPE----PPGALASHDQDTLAQLLARSPPPPHRPRLPSAESLSRRPLPAL 217
P+ GP P + P AS Q A ++ +P LPS P+
Sbjct: 257 -PIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESV---KPSLPS---------PSK 303
Query: 218 PVPEAPSPSPVPSPAPGRKGSIQDRPLPPPPPRLP 252
P + P+P P+ PG + S +P P PP P
Sbjct: 304 PPIQQPTPGKPPAQQPGHEKS---QPGPAKPPAQP 335
Score = 29.3 bits (64), Expect = 8.0
Identities = 54/263 (20%), Positives = 84/263 (31%), Gaps = 25/263 (9%)
Query: 21 GPPAGPCPPSPDLIYKIPRASGTQLAA-----PRDALEVYDVPPTALRVPSSGPYDCPAS 75
G P P SP K + T + P+ D P + P P
Sbjct: 647 GGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPL 706
Query: 76 FSHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGREP-------GPPIYAAPS 128
P +P + D P PP E P + E + P P + +
Sbjct: 707 VKQPTLHGSPSAKAKQPPEADSLSKPAPPKE--PSVPSEQDKAPVADDKPKQPKMVKPTT 764
Query: 129 NLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGA---LASHDQD 185
+L +S+ + P + T PL A PS P ++ D
Sbjct: 765 DLVSSSSATTKPDIPSSKVQSQAEEKTTP-----PLKTDSAKPSQSFPPTGEKVSPFDSK 819
Query: 186 TLAQLLARSPPPPHRPRLPSAESLSRRPLPALPVPEAPSPSPVP-SPAPGRKGSIQDRPL 244
+ + + S H PS+ES ++ + + E P + SP P K + P
Sbjct: 820 AIPRPASDSKIISHPG--PSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPT 877
Query: 245 PPPPPRLPGYGGPKVEGDPEGRE 267
PP P G P + P+ +E
Sbjct: 878 PPGPRPTAGQTVPTPQQSPKPQE 900
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 58.2 bits (139), Expect = 2e-08
Identities = 87/349 (24%), Positives = 117/349 (33%), Gaps = 78/349 (22%)
Query: 11 PP--PARPCPTSG-PPAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPT------A 61
PP P P P G P GP PP P P G + P + PP +
Sbjct: 114 PPGKPQGPPPQGGNQPQGP-PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRS 172
Query: 62 LRVPSSGPYDCPASFSHPLTRVAPQPPGEDDAPY----DVPLTPKPPAELEPDLEWEGGR 117
R P P P + + P PPG+ P + P P PP G+
Sbjct: 173 SRSPPGKPQGPPPQGGNQ-PQGPPPPPGKPQGPPPQGGNKPQGPPPP-----------GK 220
Query: 118 EPGPPIYAAPSNLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPG 177
GPP P ++ + + P+ +GG +G P P P P P G
Sbjct: 221 PQGPP----PQGDNKSQSARSPPGKPQG--PPPQGGNQPQG----PPPPPGKPQGPPPQG 270
Query: 178 ALASHDQDTLAQLLARSPPPPHRPRLP----SAESLSRRPLPALP---------VPEAPS 224
+ PPPP +P+ P ++S S R P P P+ P
Sbjct: 271 GNKP-----------QGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPP 319
Query: 225 PSPVPSPAPGRKGSIQDRPLPPPPPRLPGYGGPKVEGDPEGREMEDDPAGHHNEYEGIPM 284
P P P +G ++P PPPP P GP +G + R P + +G P
Sbjct: 320 PPPGKPQGPPPQGG--NKPQGPPPPGKP--QGPPPQGGSKSRSARSPP----GKPQGPPQ 371
Query: 285 AEEYDYVHLKGMDKAQGSRPPDQACTGDPELPERGMP-APQEALSPGEP 332
E + QG PP P+ P G P P G P
Sbjct: 372 QEG---------NNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRP 411
Score = 49.3 bits (116), Expect = 7e-06
Identities = 54/195 (27%), Positives = 74/195 (37%), Gaps = 49/195 (25%)
Query: 151 EGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQLLARSPPPPHRPRLPSAE--- 207
+GG +G P P P P P G + PPPP +P+ P +
Sbjct: 63 QGGNQPQG----PPPPPGKPQGPPPQGGNKP-----------QGPPPPGKPQGPPPQGDK 107
Query: 208 SLSRRPLPALPV---------PEAPSPSPVPSPAPGRKGSIQDRPLPPPPPRLPGYGGPK 258
S S R P P P+ P P P P +G ++P PPPP P GP
Sbjct: 108 SRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG--NKPQGPPPPGKPQ--GPP 163
Query: 259 VEGDPEGREMEDDPAGHHNEYEGIPMAEEYDYVHLKGMDKAQGSRPPDQACTGDPE-LPE 317
+GD + R P + +G P +G ++ QG PP G P+ P
Sbjct: 164 PQGDNKSRSSRSPP----GKPQGPPP---------QGGNQPQGPPPP----PGKPQGPPP 206
Query: 318 RGMPAPQEALSPGEP 332
+G PQ PG+P
Sbjct: 207 QGGNKPQGPPPPGKP 221
Score = 40.4 bits (93), Expect = 0.003
Identities = 38/145 (26%), Positives = 57/145 (39%), Gaps = 22/145 (15%)
Query: 195 PPPPHRPRLPSAESLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQDRPLPPPPPRLPGY 254
P PP +P+ P + ++ P+ P P P P +G ++P PPPP P
Sbjct: 51 PSPPGKPQGPPPQGGNQ--------PQGPPPPPGKPQGPPPQGG--NKPQGPPPPGKP-- 98
Query: 255 GGPKVEGD-------PEGREMEDDPAGHHNEYEGIPMAEEYDYVHLKGMDKAQGSRPPDQ 307
GP +GD P G+ P G + P + +G +K QG PP +
Sbjct: 99 QGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK 158
Query: 308 ACTGDPELPERGMPAPQEALSPGEP 332
G P P+ + PG+P
Sbjct: 159 P-QGPP--PQGDNKSRSSRSPPGKP 180
Score = 38.9 bits (89), Expect = 0.010
Identities = 64/253 (25%), Positives = 78/253 (30%), Gaps = 29/253 (11%)
Query: 11 PP--PARPCPTSG-PPAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPT------A 61
PP P P P G P GP PP P P G + P + PP +
Sbjct: 176 PPGKPQGPPPQGGNQPQGP-PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQS 234
Query: 62 LRVPSSGPYDCPASFSHPLTRVAPQPPGEDDAPY----DVPLTPKPPAELEPDLEWEGGR 117
R P P P + + P PPG+ P + P P PP G+
Sbjct: 235 ARSPPGKPQGPPPQGGNQ-PQGPPPPPGKPQGPPPQGGNKPQGPPPP-----------GK 282
Query: 118 EPGPPIYAAPSNLKRASALLNLYEAPEELLADGEGGGTDEGI-YDVPLLGPEAPPSPEPP 176
GPP + S P + +G G P G P P PP
Sbjct: 283 PQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPP 342
Query: 177 GA-LASHDQDTLAQLLARSPP-PPHRPRLPSAESLSRRPLPALPVPEAPSPSPVPSPAPG 234
G Q ARSPP P P + P PA P+ P P P
Sbjct: 343 GKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGP 402
Query: 235 RKGSIQDRPLPPP 247
+ RP PP
Sbjct: 403 PRPPQGGRPSRPP 415
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 57.8 bits (138), Expect = 2e-08
Identities = 92/385 (23%), Positives = 139/385 (36%), Gaps = 77/385 (20%)
Query: 5 TSVYVVPPPARPCPTSGPPAGPCPP------SPDLIYKIPRASGTQLAAPRDALEVYDVP 58
T++ +VP + CP + P C P +P++ +P S P +V +
Sbjct: 696 TTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGIS 755
Query: 59 PTALRVP-SSGPYDCP---------ASFSHPLTRVA--PQPPGEDDAPY----------- 95
T+ P +S P +CP AS LT +A P P G +P
Sbjct: 756 HTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSA 815
Query: 96 --DVPL----TPKPPAEL----EPDLEWEGGRE-------PGPPIYAAPSNLKRASALLN 138
D P+ +P P E E L ++G ++ P PP +P SA+
Sbjct: 816 GPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPP---SPKGAPTPSAVTP 872
Query: 139 LYEAPEELLADGEGGGTDEGI-YDVPLLGPEAPPSPEPPGALASHDQDTLAQL------L 191
L +P+ + + T + P GP P + P + A+ +
Sbjct: 873 L--SPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGI 930
Query: 192 ARSPPPPHRPRLPSAESLSRRPLPALPVPE-APSPSPVPSPAP-GRKGSIQDRPLPPPPP 249
SP P P P+A S + PA P P+ AP+P P+P G + + P PP
Sbjct: 931 PASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPA 990
Query: 250 RLP--GYGGPKVEGDPEGREMEDDPAGHHNEYEGIPMAEEYDYVHLKGMDKAQGSRPP-- 305
P GGP P + PA +G P A + KG + PP
Sbjct: 991 ATPPSPKGGP---ATPSPKGAPTPPAVTPPSPKGSPAATPFP----KGASTPPAATPPSP 1043
Query: 306 --DQACT----GDPELPERGMPAPQ 324
A T G P P +P+P+
Sbjct: 1044 KGSPAATPLPKGAPTTPAATLPSPK 1068
Score = 57.8 bits (138), Expect = 2e-08
Identities = 93/367 (25%), Positives = 129/367 (35%), Gaps = 57/367 (15%)
Query: 9 VVPPPARPCPTSGPPAGPCPPSPDLIYKIPRAS-GTQLAAPRDALEVYDVPPTALRVPSS 67
V PP + P + PP G P P P+ S GT P+ A V P + + +
Sbjct: 1292 VTPPSPKGGPATSPPKG-APTPPAATPPSPKGSPGTP--PPKGAPTPPAVTPPSPKGTPT 1348
Query: 68 GPYDCPASFSHPLT---RVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIY 124
P P+S P T + P PP + P P + P + G P +
Sbjct: 1349 LPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVI 1408
Query: 125 AAPSNLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQ 184
P + K+A A E +G T + V L +AP + P G A+
Sbjct: 1409 --PLSPKKAPATPVTREGAA---TPSKGDLTPPAVTPVSL--KKAPATSAPKGGPATPSS 1461
Query: 185 DTLAQLLARSPPPPHRPRLPS--AESLSRRPLPALPVP-EAP--------SPSPVPSPAP 233
L A +PP P P P A S S + PA P P AP SP VP+
Sbjct: 1462 KGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPS 1521
Query: 234 GRKGSI-----------------QDRPLP-----PPPPRLPGYGGPK-VEGDPEGREMED 270
R+ I ++ +P P P + P PK P +E
Sbjct: 1522 SRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASS 1581
Query: 271 DPAGHHNEYEGIPMAEEYDYVHLKGMDKAQGSRPPDQACTG---DPELPERGMPAPQEAL 327
PA + Y+G P +E + A S P +A T P PE+G P
Sbjct: 1582 PPAVTPSTYKGAPSPKEL------LIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKG 1635
Query: 328 SPGEPLV 334
+P P V
Sbjct: 1636 TPTSPPV 1642
Score = 57.4 bits (137), Expect = 3e-08
Identities = 82/335 (24%), Positives = 107/335 (31%), Gaps = 43/335 (12%)
Query: 11 PPPARPCPTSGPPAGPCP---PSPDLIYKIPRASGTQLAAPRDALEVYDV-PPTALRVPS 66
PP A P G PA P P P+P G +P+ A V PP+ P+
Sbjct: 965 PPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPA 1024
Query: 67 SGPYDCPASFSHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAA 126
+ P+ AS T A PP +P PL P L G P + A
Sbjct: 1025 ATPFPKGAS-----TPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGA 1079
Query: 127 PSNLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDT 186
P+ P +GG P+ P A P P G LA+
Sbjct: 1080 PT-------------PPAATPPSPKGGPATPSPKGAPM--PPAATPPSPKGGLATPPHKG 1124
Query: 187 LAQLLARSPPPPH----------RPRLPSAESLSRRPLPALPVPEAPSPSPVPSPAPGRK 236
A +PP P P P+A S + A P P+ +P +P P K
Sbjct: 1125 APTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATP-PSPK 1183
Query: 237 GSIQDRPLPPPPPRLPGYGGPKVEGDPEGREMEDDPAGHHNEYEGIPMAEEYDYV--HLK 294
G + P P P P P P+G P G P + + K
Sbjct: 1184 GGLA-TPSPKGAPTTPAATPP----SPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPK 1238
Query: 295 GMDKAQGSRPPDQACTGDPELPERGMPAPQEALSP 329
G + PP G P +G P P A P
Sbjct: 1239 GAPTTPAATPPSPK-GGPATPPPKGAPTPPAATPP 1272
Score = 50.8 bits (120), Expect = 3e-06
Identities = 82/305 (26%), Positives = 105/305 (34%), Gaps = 62/305 (20%)
Query: 7 VYVVPPPARPCPTSGPPAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPS 66
V V P RP PT AGP P +L ++P +E +P +L
Sbjct: 799 VSVSPQTKRP-PTKKGSAGPDTPIGNL------------SSPVSPVEASFLPENSLSF-- 843
Query: 67 SGPYDCPASFSHPLTRVAPQPPGEDDAPYDVPLTPK----PPAE------LEPDLEWEGG 116
G D PA+ P P P G PL+PK PP E + EG
Sbjct: 844 QGSKDSPATTHSP---TPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGP 900
Query: 117 REPGPPIYAAPSNLKRASALLNLYEAPEELLADG--EGGGTDEGIYDVPLLGPEAPPSPE 174
P P A S + AP+ + A +G T G A PSP+
Sbjct: 901 ATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPK 960
Query: 175 ----PPGALASHDQDTLAQLLARSPPPPHRPRLPSAESLSRRPLPALPVPE-APSP---- 225
PP A + A +P P P P+A S + PA P P+ AP+P
Sbjct: 961 WAPTPPAATPPSPKGGPA-----TPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVT 1015
Query: 226 --SPVPSPA----------------PGRKGSIQDRPLPPPPPRLPGYGGPKVEGDPEGRE 267
SP SPA P KGS PLP P P P +G P
Sbjct: 1016 PPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPS 1075
Query: 268 MEDDP 272
++ P
Sbjct: 1076 LKGAP 1080
Score = 47.8 bits (112), Expect = 2e-05
Identities = 99/380 (26%), Positives = 121/380 (31%), Gaps = 82/380 (21%)
Query: 11 PPPARPCPTSGPPAGPCP---PSPDLIYK-IPRASGTQLAAPRDALEVYDVPPTALRV-P 65
PP A P G PA P P P+P + P+ S P+ A PP A P
Sbjct: 988 PPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGA----STPPAATPPSP 1043
Query: 66 SSGPYDCPASFSHPLTRVA--PQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGP-- 121
P P P T A P P G P + P PPA P + G P P
Sbjct: 1044 KGSPAATPLPKGAPTTPAATLPSPKGGPATP-SLKGAPTPPAATPPSPKG-GPATPSPKG 1101
Query: 122 ---PIYAAPSNLKRASALLNLYEAPEELLA---DGEGGGTDEGIYDVPLLGPEAPPSPE- 174
P A P + K A AP A +GG P PPSP+
Sbjct: 1102 APMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKG 1161
Query: 175 --------------------PPGALASHDQDTLAQLLARSPPPPH----------RPRLP 204
P G LA+ A +PP P P P
Sbjct: 1162 GLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTP 1221
Query: 205 SAESLSRR-------PLPALPVPEAPSPSPVPSPA-PGRKGSIQDRPLPP---PPPRLPG 253
+A S + P A P A PSP PA P KG+ P PP PP G
Sbjct: 1222 AATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGA----PTPPAATPPSLKGG 1277
Query: 254 YGGPKVEGDPEGREMEDDPAGHHNEYEGIPMAEEYDYVHLKGMDKAQGSRPPD-QACTGD 312
P +G P + P+ P KG + PP + G
Sbjct: 1278 LATPPHKGAP-NPAVVTPPSPKGGPATSPP----------KGAPTPPAATPPSPKGSPGT 1326
Query: 313 PELPERGMPAPQEALSPGEP 332
P P +G P P A++P P
Sbjct: 1327 P--PPKGAPTP-PAVTPPSP 1343
Score = 44.7 bits (104), Expect = 2e-04
Identities = 70/260 (26%), Positives = 85/260 (32%), Gaps = 42/260 (16%)
Query: 13 PARPCPTSGPPAGPCPPSPDLIYKIPRASGTQLA-APRDALEVYDVPPTALRV-PSSGPY 70
PA P P P SP P G + +P+ A PP A P GP
Sbjct: 900 PATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGA----PTPPAATPPSPKGGP- 954
Query: 71 DCPASFSHPLTRVAPQPPGEDD-APYDVPLTPKPPAELEPDLEWEGGREPGPPIYAAPSN 129
+ P + AP PP +P P TP P P + GP A PS
Sbjct: 955 ------ATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGP---ATPSP 1005
Query: 130 LKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEA--PPSPEPPGALASHDQDTL 187
+ P + G + P A PPSP+ A +
Sbjct: 1006 KGAPT--------PPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAP 1057
Query: 188 AQLLARSPPPPHRPRLPSAESLSRRPLPALPVPEAPSPSPVPSPA-PGRKGSIQDRPLPP 246
A P P P P SL P P P A PSP PA P KG+ P+PP
Sbjct: 1058 TTPAATLPSPKGGPATP---SLKGAPTP----PAATPPSPKGGPATPSPKGA----PMPP 1106
Query: 247 ---PPPRLPGYGGPKVEGDP 263
PP G P +G P
Sbjct: 1107 AATPPSPKGGLATPPHKGAP 1126
Score = 41.2 bits (95), Expect = 0.002
Identities = 59/248 (23%), Positives = 81/248 (32%), Gaps = 25/248 (10%)
Query: 12 PPA--RPCPTSGP-PAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSG 68
PPA P P P P PPSP+ P GT + P + D P + V
Sbjct: 1602 PPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKM 1661
Query: 69 PYDCPASFSHPLTRVAPQPPGE---DDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYA 125
P + + P E AP P+ P + + + PPI
Sbjct: 1662 GATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRK---GPQTKKSSATSPPICP 1718
Query: 126 APSNLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQD 185
PS + L+ L + T +G +A SP+ P A
Sbjct: 1719 DPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKG--------KDASHSPKGPLAPPESKAS 1770
Query: 186 TLAQLLARSPPPPHRPRLPSAESLSRRPLPALPVPEAPSPSPVPSP----APGRKGSIQD 241
T A P P + S+S P P + +P APSP P P P G + +
Sbjct: 1771 TPLTAAAFEKVLPK----PESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLE 1826
Query: 242 RPLPPPPP 249
P P P
Sbjct: 1827 SPSKPLAP 1834
Score = 33.5 bits (75), Expect = 0.42
Identities = 68/318 (21%), Positives = 108/318 (33%), Gaps = 48/318 (15%)
Query: 1 MAIATSVYVVPPPARPCPTSGPPAGPCP--------------PSPDLIYKIPRASGTQLA 46
+ +++++ V +P PT PP P P PSP I P +
Sbjct: 26 LPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPSPSTIASTPLEVPFPQS 85
Query: 47 APRDALEVYDVPPTALRVPS-SGPYDCPASFSHPLTRVAPQPPGEDDAPYDVPLTPKPPA 105
+ AL + P +P+ GP PA+ + +AP G + + L P
Sbjct: 86 SSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIAPTLKGTPSSSAPLALVALAPH 145
Query: 106 ELEPDLEWEGGREPGPPIYAAPSN---------LKRASALLNLYEAPEELLADGEGGGTD 156
++ + PP A + + + NL + P E++ + +G +
Sbjct: 146 SVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSP 205
Query: 157 EGIYD-VPL----------LGPEAPPSPEPPGALA---SHDQDTLAQLLARSPPPPHRPR 202
I VP G + P P LA +DT + SP P
Sbjct: 206 PCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLS 265
Query: 203 L------PSAESLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQDRPLPPP---PPRLPG 253
L P+A SLS + LP + + + P P GS PL +L G
Sbjct: 266 LKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTPPDFPISLGS-HLAPLHQSSFGSVQLLG 324
Query: 254 YGGPKVEGDPEGREMEDD 271
GP DP + + D
Sbjct: 325 QTGPSALSDPTVKTISVD 342
>gi|33356148 formin-like 1 [Homo sapiens]
Length = 1100
Score = 57.8 bits (138), Expect = 2e-08
Identities = 56/167 (33%), Positives = 65/167 (38%), Gaps = 25/167 (14%)
Query: 117 REPGPPIYAAPSNLKRASALLNLYEAPEEL----LADGEGGGTDEGIYDVPLLGPEAPPS 172
R P P A P+ R SAL E EE + G G I V + P +
Sbjct: 457 RRPPEPEKAPPAAPTRPSALELKVEELEEKGLIRILRGPGDAVSIEILPVAVATPSGGDA 516
Query: 173 PEP--PGALASHDQDTLAQLL--ARSPPPPHRPRLPSAESL-------------SRRPLP 215
P P P S D A+ A PPPP P LPS + S P P
Sbjct: 517 PTPGVPTGSPSPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQAPPLPGSPEPPP 576
Query: 216 ALPVP-EAPSPSPVPSPAPGRKGSIQDRPLPPPPPRLPGYGGPKVEG 261
A P+P + P P P P P PG G + P PPPPP P G P G
Sbjct: 577 APPLPGDLPPPPPPPPPPPGTDGPVPPPP-PPPPP--PPGGPPDALG 620
Score = 45.8 bits (107), Expect = 8e-05
Identities = 62/220 (28%), Positives = 76/220 (34%), Gaps = 51/220 (23%)
Query: 28 PPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGPYDCPASFSHPLTRVAPQP 87
PP P+ K P A+ T+ +A L+V ++ L GP D + S + VA
Sbjct: 459 PPEPE---KAPPAAPTRPSALE--LKVEELEEKGLIRILRGPGD---AVSIEILPVAVAT 510
Query: 88 PGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAAPSNLKRASALLNLYEAPEELL 147
P DAP T P +L P E G P PP L + EAP
Sbjct: 511 PSGGDAPTPGVPTGSPSPDLAPAAEPAPGAAPPPP--------PPLPGLPSPQEAPPSAP 562
Query: 148 ADGEGGGTDEGIYDVPLLG-PEAPPSPEPPGALASHDQDTLAQLLARSPPPPHRPRLPSA 206
PL G PE PP+P PG L PPPP P P
Sbjct: 563 PQAP-----------PLPGSPEPPPAPPLPGDLP--------------PPPPPPPPPPGT 597
Query: 207 ESLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQDRPLPP 246
+ PVP P P P P P +D L P
Sbjct: 598 DG---------PVPPPPPPPPPPPGGPPDALGRRDSELGP 628
Score = 40.0 bits (92), Expect = 0.005
Identities = 42/130 (32%), Positives = 46/130 (35%), Gaps = 18/130 (13%)
Query: 12 PPARPCPTSGPPAGPCPPSPDLIYKIPRASGTQLAAPRDA--LEVYDVPPTALRVPSSGP 69
P A P P + PP P PP P L P +AP A L PP A +P P
Sbjct: 532 PAAEPAPGAAPP--PPPPLPGL----PSPQEAPPSAPPQAPPLPGSPEPPPAPPLPGDLP 585
Query: 70 YDCPASFSHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYA-APS 128
P P PPG D P P PP PD E GP + A P
Sbjct: 586 PPPPPP---------PPPPGTDGPVPPPPPPPPPPPGGPPDALGRRDSELGPGVKAKKPI 636
Query: 129 NLKRASALLN 138
K LLN
Sbjct: 637 QTKFRMPLLN 646
Score = 39.7 bits (91), Expect = 0.006
Identities = 50/189 (26%), Positives = 59/189 (31%), Gaps = 59/189 (31%)
Query: 7 VYVVPPPARPCPTSGPPAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPS 66
V V P PT G P G PSPDL P A AAP + +P PS
Sbjct: 506 VAVATPSGGDAPTPGVPTGS--PSPDLA---PAAEPAPGAAPPPPPPLPGLPSPQEAPPS 560
Query: 67 SGPYDCPASFSHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAA 126
+ P P S P+PP P D+P P PP P PP
Sbjct: 561 APPQAPPLPGS-------PEPPPAPPLPGDLPPPPPPP--------------PPPP---- 595
Query: 127 PSNLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDT 186
GTD + P P PP PP AL D +
Sbjct: 596 ---------------------------GTDGPVPPPP--PPPPPPPGGPPDALGRRDSEL 626
Query: 187 LAQLLARSP 195
+ A+ P
Sbjct: 627 GPGVKAKKP 635
>gi|54860105 nadrin isoform 2 [Homo sapiens]
Length = 803
Score = 57.0 bits (136), Expect = 4e-08
Identities = 63/222 (28%), Positives = 84/222 (37%), Gaps = 59/222 (26%)
Query: 69 PYDCPASFSHPLTRV----APQPPGEDDAPYDVP--------------LTPKPPAELEPD 110
P++ H L R AP PP + P P L+PKPP
Sbjct: 540 PHNAAGPSPHTLRRAVKKPAPAPPKPGNPPPGHPGGQSSSGTSQHPPSLSPKPPTRSPSP 599
Query: 111 LEWEGGREPGPPIYAAPSNL---KRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGP 167
G+ PG P +APS L +R S+ L+ +AP T PL+
Sbjct: 600 PTQHTGQPPGQP--SAPSQLSAPRRYSSSLSPIQAPNHPPPQPPTQAT-------PLMHT 650
Query: 168 EAPPSPEPPGALASHDQDTLAQLLARSPPPPHRPRLPSAESLSRRPLPALPVPEA----- 222
+ P S PP +A + L Q S PP P PS L ++ P+LP P+
Sbjct: 651 K-PNSQGPPNPMALPSEHGLEQ---PSHTPPQTPTPPSTPPLGKQN-PSLPAPQTLAGGN 705
Query: 223 -----------PSPSPVPSPAPGRKGSIQDRPLPPPPPRLPG 253
P P PVP P ++RP PPPP+ PG
Sbjct: 706 PETAQPHAGTLPRPRPVPKP--------RNRPSVPPPPQPPG 739
Score = 35.4 bits (80), Expect = 0.11
Identities = 52/222 (23%), Positives = 71/222 (31%), Gaps = 58/222 (26%)
Query: 11 PPPARPCP----TSGPPAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPS 66
PP P P T PP P PS QL+APR Y + ++ P+
Sbjct: 592 PPTRSPSPPTQHTGQPPGQPSAPS-------------QLSAPRR----YSSSLSPIQAPN 634
Query: 67 SGP-----------YDCPASFSHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEG 115
P + P S P P G + + P TP PP+ P L +
Sbjct: 635 HPPPQPPTQATPLMHTKPNSQGPPNPMALPSEHGLEQPSHTPPQTPTPPST--PPLGKQN 692
Query: 116 GREPGPPIYAAPSNLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEP 175
P P A N + A P + P P PP P+P
Sbjct: 693 PSLPAPQTLAG-GNPETAQPHAGTLPRPRPV--------------PKPRNRPSVPPPPQP 737
Query: 176 PGALASHDQD------TLAQLLARS---PPPPHRPRLPSAES 208
PG ++ D T ++++ S PHR P S
Sbjct: 738 PGVHSAGDSSLTNTAPTASKIVTDSNSRVSEPHRSIFPEMHS 779
>gi|110556644 zinc finger protein, multitype 1 [Homo sapiens]
Length = 1006
Score = 57.0 bits (136), Expect = 4e-08
Identities = 73/274 (26%), Positives = 93/274 (33%), Gaps = 41/274 (14%)
Query: 11 PPPARPCPTSGPPAGPCPPSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGPY 70
PPP RP GPP PP+P + +L A PP P S P
Sbjct: 712 PPPRRPAAPPGPPGPAAPPAPSPAAPVRTRRRRKLYELHAAGAPPPPPPGHAPAPES-PR 770
Query: 71 DCPASFSHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAAPSNL 130
S S P A P D P D+ P+ P PG P A ++
Sbjct: 771 PGSGSGSGPGLAPARSPGPAADGPIDLSKKPRRPL-------------PGAPA-PALADY 816
Query: 131 KRASALLNLYEAPEELLADGE---GGGTDEGIYDVPLLG-PEAPPSPEPPGALASHDQDT 186
+A + + E LA + G +P P PP+ G L H +
Sbjct: 817 HECTACRVSFHSLEAYLAHKKYSCPAAPPPGALGLPAAACPYCPPNGPVRGDLLEHFRLA 876
Query: 187 LAQLL----------ARSP----PPPHRPRLPSAESLSRRPLPAL-PVPEAPSPSPVPSP 231
LL AR+P P P S + SR P L P P+ P P P PSP
Sbjct: 877 HGLLLGAPLAGPGVEARTPADRGPSPAPAPAASPQPGSRGPRDGLGPEPQEPPPGPPPSP 936
Query: 232 APGRKGSIQDRPLPPPPPRLPGYGGPKVEGDPEG 265
A + PPPP P Y V+ +G
Sbjct: 937 AAAPEA-------VPPPPAPPSYSDKGVQTPSKG 963
Score = 38.9 bits (89), Expect = 0.010
Identities = 45/161 (27%), Positives = 61/161 (37%), Gaps = 31/161 (19%)
Query: 78 HPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAAPSNLKRASALL 137
HP T++ P G + P A+L G P P +P ++A A
Sbjct: 389 HPATKLPPDSLGSFQQQHTALQGPLASADL--------GLAPTP----SPGLDRKALAEA 436
Query: 138 NLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQLLARSPPP 197
EA E LA + GG+ E PP+ + + ++ A +L P
Sbjct: 437 TNGEARAEPLA--QNGGSSE------------PPAAPRSIKVEAVEEPEAAPILGPGEPG 482
Query: 198 PHRP-RLPSAESLSRRPLPALPVPEAPSPSPVPSPAPGRKG 237
P P R PS S P PA E SP+P SP PG G
Sbjct: 483 PQAPSRTPSPRS----PAPARVKAELSSPTPGSSPVPGELG 519
Score = 34.7 bits (78), Expect = 0.19
Identities = 40/130 (30%), Positives = 50/130 (38%), Gaps = 24/130 (18%)
Query: 13 PARPCPTS-GPPAGPCPPSP-------DLIYKIPRASGTQLAAPRDALEVYDVPPTALRV 64
PA P P + G PA CP P DL+ A G L AP V P A R
Sbjct: 841 PAAPPPGALGLPAAACPYCPPNGPVRGDLLEHFRLAHGLLLGAPLAGPGVEARTP-ADRG 899
Query: 65 PSSGPYDCPASFSHPLTR-----VAPQP--------PGEDDAPYDVPLTPKPPAELEPDL 111
PS P PA+ P +R + P+P P AP VP P PP+ + +
Sbjct: 900 PSPAP--APAASPQPGSRGPRDGLGPEPQEPPPGPPPSPAAAPEAVPPPPAPPSYSDKGV 957
Query: 112 EWEGGREPGP 121
+ P P
Sbjct: 958 QTPSKGTPAP 967
Score = 32.3 bits (72), Expect = 0.95
Identities = 25/55 (45%), Positives = 31/55 (56%), Gaps = 14/55 (25%)
Query: 220 PEAPSPSPVPSPAPGRKGSIQDRPLPPPPPRLPGYGGPK-VEG-DPEGREMEDDP 272
PEAPSP PS + + P P PPP P GGPK +EG +PE R E++P
Sbjct: 40 PEAPSP---PS-------ADVNSPPPLPPPTSP--GGPKELEGQEPEPRPTEEEP 82
Score = 30.0 bits (66), Expect = 4.7
Identities = 37/139 (26%), Positives = 45/139 (32%), Gaps = 19/139 (13%)
Query: 211 RRPLPALPVPEAPSPSPVPSPAPGRKGSIQDRPLPPPPP--RLPGYGGPKVEGDPEG--- 265
RR P P P P+ AP + + D P P P R G GG D G
Sbjct: 603 RRAPEDAPAARRPKAPPGPARAPPGQPAEPDAPRSSPGPGAREEGAGGAATPEDGAGGRG 662
Query: 266 -----------REMEDDPAGHHNEYEGIPMAEEYDYVHLKGMDKAQGSRPPDQACTGDPE 314
+ EDDP+ E I + Y K A PP + P
Sbjct: 663 SEGSQSPGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHDPPPRRPAAPPG 722
Query: 315 LPERGMPAPQEALSPGEPL 333
P PA A SP P+
Sbjct: 723 PPG---PAAPPAPSPAAPV 738
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.134 0.412
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,769,742
Number of Sequences: 37866
Number of extensions: 2140536
Number of successful extensions: 29254
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 460
Number of HSP's successfully gapped in prelim test: 1691
Number of HSP's that attempted gapping in prelim test: 11894
Number of HSP's gapped (non-prelim): 10785
length of query: 468
length of database: 18,247,518
effective HSP length: 106
effective length of query: 362
effective length of database: 14,233,722
effective search space: 5152607364
effective search space used: 5152607364
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.