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Search of human proteins with 14589866
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|14589866 aspartate beta-hydroxylase isoform a [Homo sapiens]
(758 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|14589866 aspartate beta-hydroxylase isoform a [Homo sapiens] 1553 0.0
gi|14589860 aspartate beta-hydroxylase isoform c [Homo sapiens] 634 0.0
gi|14589864 aspartate beta-hydroxylase isoform b [Homo sapiens] 562 e-160
gi|14589862 aspartate beta-hydroxylase isoform d [Homo sapiens] 166 1e-40
gi|9910364 aspartate beta-hydroxylase isoform e [Homo sapiens] 155 1e-37
gi|194328779 aspartate beta-hydroxylase domain containing 2 [Hom... 103 8e-22
gi|38708313 aspartate beta-hydroxylase domain containing 1 [Homo... 85 2e-16
gi|150378543 MYST histone acetyltransferase (monocytic leukemia)... 56 1e-07
gi|150378463 MYST histone acetyltransferase (monocytic leukemia)... 56 1e-07
gi|150378493 MYST histone acetyltransferase (monocytic leukemia)... 56 1e-07
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 55 3e-07
gi|110349719 titin isoform N2-A [Homo sapiens] 50 6e-06
gi|148746195 trichohyalin [Homo sapiens] 50 6e-06
gi|17975763 myelin transcription factor 1 [Homo sapiens] 49 1e-05
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)... 49 1e-05
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 49 1e-05
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 49 2e-05
gi|110347568 centrosomal protein 152kDa [Homo sapiens] 49 2e-05
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 48 3e-05
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 47 5e-05
gi|104526627 triadin [Homo sapiens] 47 9e-05
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 46 1e-04
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 46 1e-04
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 46 1e-04
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 46 1e-04
gi|221219020 NYD-SP11 protein [Homo sapiens] 45 3e-04
gi|210032580 SET domain containing 1B [Homo sapiens] 45 3e-04
gi|83415184 transmembrane and tetratricopeptide repeat containin... 44 4e-04
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 44 7e-04
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 44 7e-04
>gi|14589866 aspartate beta-hydroxylase isoform a [Homo sapiens]
Length = 758
Score = 1553 bits (4022), Expect = 0.0
Identities = 758/758 (100%), Positives = 758/758 (100%)
Query: 1 MAQRKNAKSSGNSSSSGSGSGSTSAGSSSPGARRETKHGGHKNGRKGGLSGTSFFTWFMV 60
MAQRKNAKSSGNSSSSGSGSGSTSAGSSSPGARRETKHGGHKNGRKGGLSGTSFFTWFMV
Sbjct: 1 MAQRKNAKSSGNSSSSGSGSGSTSAGSSSPGARRETKHGGHKNGRKGGLSGTSFFTWFMV 60
Query: 61 IALLGVWTSVAVVWFDLVDYEEVLGKLGIYDADGDGDFDVDDAKVLLGLKERSTSEPAVP 120
IALLGVWTSVAVVWFDLVDYEEVLGKLGIYDADGDGDFDVDDAKVLLGLKERSTSEPAVP
Sbjct: 61 IALLGVWTSVAVVWFDLVDYEEVLGKLGIYDADGDGDFDVDDAKVLLGLKERSTSEPAVP 120
Query: 121 PEEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQSLLHEMVHAEHVEGEDLQQEDGPTGEPQ 180
PEEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQSLLHEMVHAEHVEGEDLQQEDGPTGEPQ
Sbjct: 121 PEEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQSLLHEMVHAEHVEGEDLQQEDGPTGEPQ 180
Query: 181 QEDDEFLMATDVDDRFETLEPEVSHEETEHSYHVEETVSQDCNQDMEEMMSEQENPDSSE 240
QEDDEFLMATDVDDRFETLEPEVSHEETEHSYHVEETVSQDCNQDMEEMMSEQENPDSSE
Sbjct: 181 QEDDEFLMATDVDDRFETLEPEVSHEETEHSYHVEETVSQDCNQDMEEMMSEQENPDSSE 240
Query: 241 PVVEDERLHHDTDDVTYQVYEEQAVYEPLENEGIEITEVTAPPEDNPVEDSQVIVEEVSI 300
PVVEDERLHHDTDDVTYQVYEEQAVYEPLENEGIEITEVTAPPEDNPVEDSQVIVEEVSI
Sbjct: 241 PVVEDERLHHDTDDVTYQVYEEQAVYEPLENEGIEITEVTAPPEDNPVEDSQVIVEEVSI 300
Query: 301 FPVEEQQEVPPETNRKTDDPEQKAKVKKKKPKLLNKFDKTIKAELDAAEKLRKRGKIEEA 360
FPVEEQQEVPPETNRKTDDPEQKAKVKKKKPKLLNKFDKTIKAELDAAEKLRKRGKIEEA
Sbjct: 301 FPVEEQQEVPPETNRKTDDPEQKAKVKKKKPKLLNKFDKTIKAELDAAEKLRKRGKIEEA 360
Query: 361 VNAFKELVRKYPQSPRARYGKAQCEDDLAEKRRSNEVLRGAIETYQEVASLPDVPADLLK 420
VNAFKELVRKYPQSPRARYGKAQCEDDLAEKRRSNEVLRGAIETYQEVASLPDVPADLLK
Sbjct: 361 VNAFKELVRKYPQSPRARYGKAQCEDDLAEKRRSNEVLRGAIETYQEVASLPDVPADLLK 420
Query: 421 LSLKRRSDRQQFLGHMRGSLLTLQRLVQLFPNDTSLKNDLGVGYLLIGDNDNAKKVYEEV 480
LSLKRRSDRQQFLGHMRGSLLTLQRLVQLFPNDTSLKNDLGVGYLLIGDNDNAKKVYEEV
Sbjct: 421 LSLKRRSDRQQFLGHMRGSLLTLQRLVQLFPNDTSLKNDLGVGYLLIGDNDNAKKVYEEV 480
Query: 481 LSVTPNDGFAKVHYGFILKAQNKIAESIPYLKEGIESGDPGTDDGRFYFHLGDAMQRVGN 540
LSVTPNDGFAKVHYGFILKAQNKIAESIPYLKEGIESGDPGTDDGRFYFHLGDAMQRVGN
Sbjct: 481 LSVTPNDGFAKVHYGFILKAQNKIAESIPYLKEGIESGDPGTDDGRFYFHLGDAMQRVGN 540
Query: 541 KEAYKWYELGHKRGHFASVWQRSLYNVNGLKAQPWWTPKETGYTELVKSLERNWKLIRDE 600
KEAYKWYELGHKRGHFASVWQRSLYNVNGLKAQPWWTPKETGYTELVKSLERNWKLIRDE
Sbjct: 541 KEAYKWYELGHKRGHFASVWQRSLYNVNGLKAQPWWTPKETGYTELVKSLERNWKLIRDE 600
Query: 601 GLAVMDKAKGLFLPEDENLREKGDWSQFTLWQQGRRNENACKGAPKTCTLLEKFPETTGC 660
GLAVMDKAKGLFLPEDENLREKGDWSQFTLWQQGRRNENACKGAPKTCTLLEKFPETTGC
Sbjct: 601 GLAVMDKAKGLFLPEDENLREKGDWSQFTLWQQGRRNENACKGAPKTCTLLEKFPETTGC 660
Query: 661 RRGQIKYSIMHPGTHVWPHTGPTNCRLRMHLGLVIPKEGCKIRCANETKTWEEGKVLIFD 720
RRGQIKYSIMHPGTHVWPHTGPTNCRLRMHLGLVIPKEGCKIRCANETKTWEEGKVLIFD
Sbjct: 661 RRGQIKYSIMHPGTHVWPHTGPTNCRLRMHLGLVIPKEGCKIRCANETKTWEEGKVLIFD 720
Query: 721 DSFEHEVWQDASSFRLIFIVDVWHPELTPQQRRSLPAI 758
DSFEHEVWQDASSFRLIFIVDVWHPELTPQQRRSLPAI
Sbjct: 721 DSFEHEVWQDASSFRLIFIVDVWHPELTPQQRRSLPAI 758
>gi|14589860 aspartate beta-hydroxylase isoform c [Homo sapiens]
Length = 313
Score = 634 bits (1636), Expect = 0.0
Identities = 312/313 (99%), Positives = 313/313 (100%)
Query: 1 MAQRKNAKSSGNSSSSGSGSGSTSAGSSSPGARRETKHGGHKNGRKGGLSGTSFFTWFMV 60
MAQRKNAKSSGNSSSSGSGSGSTSAGSSSPGARRETKHGGHKNGRKGGLSGTSFFTWFMV
Sbjct: 1 MAQRKNAKSSGNSSSSGSGSGSTSAGSSSPGARRETKHGGHKNGRKGGLSGTSFFTWFMV 60
Query: 61 IALLGVWTSVAVVWFDLVDYEEVLGKLGIYDADGDGDFDVDDAKVLLGLKERSTSEPAVP 120
IALLGVWTSVAVVWFDLVDYEEVLGKLGIYDADGDGDFDVDDAKVLLGLKERSTSEPAVP
Sbjct: 61 IALLGVWTSVAVVWFDLVDYEEVLGKLGIYDADGDGDFDVDDAKVLLGLKERSTSEPAVP 120
Query: 121 PEEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQSLLHEMVHAEHVEGEDLQQEDGPTGEPQ 180
PEEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQSLLHEMVHAEHVEGEDLQQEDGPTGEPQ
Sbjct: 121 PEEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQSLLHEMVHAEHVEGEDLQQEDGPTGEPQ 180
Query: 181 QEDDEFLMATDVDDRFETLEPEVSHEETEHSYHVEETVSQDCNQDMEEMMSEQENPDSSE 240
QEDDEFLMATDVDDRFETLEPEVSHEETEHSYHVEETVSQDCNQDMEEMMSEQENPDSSE
Sbjct: 181 QEDDEFLMATDVDDRFETLEPEVSHEETEHSYHVEETVSQDCNQDMEEMMSEQENPDSSE 240
Query: 241 PVVEDERLHHDTDDVTYQVYEEQAVYEPLENEGIEITEVTAPPEDNPVEDSQVIVEEVSI 300
PVVEDERLHHDTDDVTYQVYEEQAVYEPLENEGIEITEVTAPPEDNPVEDSQVIVEEVSI
Sbjct: 241 PVVEDERLHHDTDDVTYQVYEEQAVYEPLENEGIEITEVTAPPEDNPVEDSQVIVEEVSI 300
Query: 301 FPVEEQQEVPPET 313
FPVEEQQEVPP+T
Sbjct: 301 FPVEEQQEVPPDT 313
>gi|14589864 aspartate beta-hydroxylase isoform b [Homo sapiens]
Length = 299
Score = 562 bits (1449), Expect = e-160
Identities = 278/295 (94%), Positives = 280/295 (94%), Gaps = 15/295 (5%)
Query: 34 RETKHGGHKNGRKGGLSGTSFFTWFMVIALLGVWTSVAVVWFDLVDYEEVL--------- 84
+ETKHGGHKNGRKGGLSGTSFFTWFMVIALLGVWTSVAVVWFDLVDYEEVL
Sbjct: 5 KETKHGGHKNGRKGGLSGTSFFTWFMVIALLGVWTSVAVVWFDLVDYEEVLAKAKDFRYN 64
Query: 85 ------GKLGIYDADGDGDFDVDDAKVLLGLKERSTSEPAVPPEEAEPHTEPEEQVPVEA 138
GKLGIYDADGDGDFDVDDAKVLLGLKERSTSEPAVPPEEAEPHTEPEEQVPVEA
Sbjct: 65 LSEVLQGKLGIYDADGDGDFDVDDAKVLLGLKERSTSEPAVPPEEAEPHTEPEEQVPVEA 124
Query: 139 EPQNIEDEAKEQIQSLLHEMVHAEHVEGEDLQQEDGPTGEPQQEDDEFLMATDVDDRFET 198
EPQNIEDEAKEQIQSLLHEMVHAEHVEGEDLQQEDGPTGEPQQEDDEFLMATDVDDRFET
Sbjct: 125 EPQNIEDEAKEQIQSLLHEMVHAEHVEGEDLQQEDGPTGEPQQEDDEFLMATDVDDRFET 184
Query: 199 LEPEVSHEETEHSYHVEETVSQDCNQDMEEMMSEQENPDSSEPVVEDERLHHDTDDVTYQ 258
LEPEVSHEETEHSYHVEETVSQDCNQDMEEMMSEQENPDSSEPVVEDERLHHDTDDVTYQ
Sbjct: 185 LEPEVSHEETEHSYHVEETVSQDCNQDMEEMMSEQENPDSSEPVVEDERLHHDTDDVTYQ 244
Query: 259 VYEEQAVYEPLENEGIEITEVTAPPEDNPVEDSQVIVEEVSIFPVEEQQEVPPET 313
VYEEQAVYEPLENEGIEITEVTAPPEDNPVEDSQVIVEEVSIFPVEEQQEVPP+T
Sbjct: 245 VYEEQAVYEPLENEGIEITEVTAPPEDNPVEDSQVIVEEVSIFPVEEQQEVPPDT 299
>gi|14589862 aspartate beta-hydroxylase isoform d [Homo sapiens]
Length = 210
Score = 166 bits (419), Expect = 1e-40
Identities = 87/156 (55%), Positives = 109/156 (69%), Gaps = 10/156 (6%)
Query: 34 RETKHGGHKNGRKGGLSGTSFFTWFMVIALLGVWTSVAVVWFDLVDYEEVLGKLGIYDAD 93
+ETKHGGHKNGRKGGLSGTSFFTWFMVIALLGVWTSVAVVWFDLVDYEEVLGKLGIYDAD
Sbjct: 5 KETKHGGHKNGRKGGLSGTSFFTWFMVIALLGVWTSVAVVWFDLVDYEEVLGKLGIYDAD 64
Query: 94 GDGDFDVDDAKVLL----GLKERSTSEPAVPPEEAEPHTEPEEQVPVEAEPQNIEDEAKE 149
GDGDFDVDDAKVLL G+ +R T A E + + E++ P + E+ K
Sbjct: 65 GDGDFDVDDAKVLLEGPSGVAKRKTK--AKVKELTKEELKKEKEKPESRKESKNEERKKG 122
Query: 150 QIQSLLHEMVHAEHVEGEDLQQEDGPTGEPQQEDDE 185
+ + + + + + DL +++ P G+ +E ++
Sbjct: 123 KKEDVRKD----KKIADADLSRKESPKGKKDREKEK 154
>gi|9910364 aspartate beta-hydroxylase isoform e [Homo sapiens]
Length = 225
Score = 155 bits (393), Expect = 1e-37
Identities = 87/171 (50%), Positives = 109/171 (63%), Gaps = 25/171 (14%)
Query: 34 RETKHGGHKNGRKGGLSGTSFFTWFMVIALLGVWTSVAVVWFDLVDYEEVL--------- 84
+ETKHGGHKNGRKGGLSGTSFFTWFMVIALLGVWTSVAVVWFDLVDYEEVL
Sbjct: 5 KETKHGGHKNGRKGGLSGTSFFTWFMVIALLGVWTSVAVVWFDLVDYEEVLAKAKDFRYN 64
Query: 85 ------GKLGIYDADGDGDFDVDDAKVLL----GLKERSTSEPAVPPEEAEPHTEPEEQV 134
GKLGIYDADGDGDFDVDDAKVLL G+ +R T A E + + E++
Sbjct: 65 LSEVLQGKLGIYDADGDGDFDVDDAKVLLEGPSGVAKRKTK--AKVKELTKEELKKEKEK 122
Query: 135 PVEAEPQNIEDEAKEQIQSLLHEMVHAEHVEGEDLQQEDGPTGEPQQEDDE 185
P + E+ K + + + + + + DL +++ P G+ +E ++
Sbjct: 123 PESRKESKNEERKKGKKEDVRKD----KKIADADLSRKESPKGKKDREKEK 169
>gi|194328779 aspartate beta-hydroxylase domain containing 2 [Homo
sapiens]
Length = 369
Score = 103 bits (256), Expect = 8e-22
Identities = 63/178 (35%), Positives = 91/178 (51%), Gaps = 7/178 (3%)
Query: 587 VKSLERNWKLIRDEGLAVMDKAKGLFLPED--ENLREKGDWSQFTLWQQGRRNENACKGA 644
V+ LERN++ I E + LP+ N G+W F L QG C+
Sbjct: 188 VEVLERNFQTILCEFETLYKAFSNCSLPQGWKMNSTPSGEWFTFYLVNQGVCVPRNCRKC 247
Query: 645 PKTCTLLEKFPETTGCRR-GQIKYSIMHPGTHVWPHTGPTNCRLRMHLGLVIPKEGCKIR 703
P+T LL G G S++ PGT + H GPTN R+R HLGL P GC++
Sbjct: 248 PRTYRLLGSLRTCIGNNVFGNACISVLSPGTVITEHYGPTNIRIRCHLGLKTP-NGCELV 306
Query: 704 CANETKTWEEGKVLIFDDSFEHEVWQDASSF---RLIFIVDVWHPELTPQQRRSLPAI 758
E + W EG+ L+FDDSF H + + S+ R++F+VD+WHP + +R++L I
Sbjct: 307 VGGEPQCWAEGRCLLFDDSFLHAAFHEGSAEDGPRVVFMVDLWHPNVAAAERQALDFI 364
>gi|38708313 aspartate beta-hydroxylase domain containing 1 [Homo
sapiens]
Length = 390
Score = 85.1 bits (209), Expect = 2e-16
Identities = 48/133 (36%), Positives = 68/133 (51%), Gaps = 5/133 (3%)
Query: 627 QFTLWQQGRRNENACKGAPKTCTLLEKFPETTGCRR-GQIKYSIMHPGTHVWPHTGPTNC 685
Q L+Q GR + C+ P L G +S++ PG + GPTN
Sbjct: 251 QLLLYQAGRCQPSNCRRCPGAYRALRGLRSFMSANTFGNAGFSVLLPGARLEGRCGPTNA 310
Query: 686 RLRMHLGLVIPKEGCKIRCANETKTWEEGKVLIFDDSFEHEVWQDAS---SFRLIFIVDV 742
R+R HLGL IP GC++ E + W EG L+ DDSF H V + S R++FIVD+
Sbjct: 311 RVRCHLGLKIP-PGCELVVGGEPQCWAEGHCLLVDDSFLHTVAHNGSPEDGPRVVFIVDL 369
Query: 743 WHPELTPQQRRSL 755
WHP + +R++L
Sbjct: 370 WHPNVAGAERQAL 382
>gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 55.8 bits (133), Expect = 1e-07
Identities = 66/279 (23%), Positives = 115/279 (41%), Gaps = 43/279 (15%)
Query: 122 EEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQSLLHEMVHAEHVEGEDLQQEDGPTGEPQQ 181
+E+E EP+E +P + +E KE+ + + E AE E ED + P P
Sbjct: 1205 QESEETVEPKEDMP-------LPEERKEE-EEMQAEAEEAEEGEEEDAASSEVPAASPAD 1256
Query: 182 EDDEFLMATDVDDRFETLEPEVSHEETEHSYHVEETVSQDCNQDMEEMMSEQENPDSSEP 241
+ ET EPEV EE + E+ S++ Q++EE E+E ++E
Sbjct: 1257 SSNS--------PETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAET 1308
Query: 242 VVEDERLHHDTDD-----VTYQVYEEQAVYEPLENE-GIEITEVTAPPEDN-----PVED 290
D+ D DD + EEQ E ++ E G++ + + A + + E+
Sbjct: 1309 AQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEE 1368
Query: 291 SQVIVEEVSIFPVEEQQEVPPETNRKTDDPEQKAKVKKKKPKLLNKFDKTIKAELDAAEK 350
+++ EE P + V + DD E+ + K++ +L + ++ +ELD
Sbjct: 1369 TELDSEEEQ--PSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEE-EEIPHSELDL--- 1422
Query: 351 LRKRGKIEEAVNAFKELVRKYPQSPRARYGKAQCEDDLA 389
E V A + L ++ Y CE+ LA
Sbjct: 1423 --------ETVQAVQSLTQEESSEHEGAY--QDCEETLA 1451
Score = 43.5 bits (101), Expect = 7e-04
Identities = 63/253 (24%), Positives = 98/253 (38%), Gaps = 49/253 (19%)
Query: 111 ERSTSEPAVPPEEAEPHT-----EPEEQVPV--EAEPQNIEDEAKEQIQSLLHEM----- 158
E T EP V EE +P + EE+ E EP+ ED A E Q+ H+
Sbjct: 1262 ETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDD 1321
Query: 159 VHAEHVEGEDLQQEDGPTGEPQQED----DEFLMATDVDDRFETLEPEVSHEETEHSYHV 214
H E + ++L+++ PT E +E+ + FL A R + + E + ++E
Sbjct: 1322 GHLESTKKKELEEQ--PTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSE----- 1374
Query: 215 EETVSQDCNQDMEEMM-SEQENPDSS-------EPVVEDERLHHDTDDVTYQVYEEQAVY 266
EE S D + E+M SE ++ + S E E+E H + D T Q +
Sbjct: 1375 EEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQE 1434
Query: 267 EPLENEGI---------------EITEVTAPPEDNPVEDSQVIVEEVSIFPVEEQQEVPP 311
E E+EG T+ P+ + VED P+ Q P
Sbjct: 1435 ESSEHEGAYQDCEETLAACQTLQSYTQADEDPQMSMVEDCHASEHN---SPISSVQSHPS 1491
Query: 312 ETNRKTDDPEQKA 324
++ R P A
Sbjct: 1492 QSVRSVSSPNVPA 1504
Score = 38.9 bits (89), Expect = 0.018
Identities = 49/203 (24%), Positives = 86/203 (42%), Gaps = 37/203 (18%)
Query: 113 STSEPAVPPEEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQSLLHEMVHAEHVEGEDLQQE 172
S+ PA P ++ E E + EP+ E+E K ++ E + E+ QQE
Sbjct: 1246 SSEVPAASPADSSNSPETETK-----EPEVEEEEEKPRVSE--------EQRQSEEEQQE 1292
Query: 173 DGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEETEHSYHVEET-----VSQDCNQDME 227
EP+ E++E D ET + + + E H+E T Q +D++
Sbjct: 1293 ---LEEPEPEEEE-------DAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDVK 1342
Query: 228 EMMSEQENPDSSEPVVEDERLHHDTDDVTYQVYEEQAVYEPLENEGIEITEVTAPPEDNP 287
E QE+ + E++ D ++ EEQ P + + ++E A ED+
Sbjct: 1343 EEPGVQESFLDANMQKSREKI-KDKEETELDSEEEQ----PSHDTSV-VSEQMAGSEDDH 1396
Query: 288 VEDSQVIVEEVSIFPVEEQQEVP 310
EDS E + ++E++E+P
Sbjct: 1397 EEDSHTKEE---LIELKEEEEIP 1416
>gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 55.8 bits (133), Expect = 1e-07
Identities = 66/279 (23%), Positives = 115/279 (41%), Gaps = 43/279 (15%)
Query: 122 EEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQSLLHEMVHAEHVEGEDLQQEDGPTGEPQQ 181
+E+E EP+E +P + +E KE+ + + E AE E ED + P P
Sbjct: 1205 QESEETVEPKEDMP-------LPEERKEE-EEMQAEAEEAEEGEEEDAASSEVPAASPAD 1256
Query: 182 EDDEFLMATDVDDRFETLEPEVSHEETEHSYHVEETVSQDCNQDMEEMMSEQENPDSSEP 241
+ ET EPEV EE + E+ S++ Q++EE E+E ++E
Sbjct: 1257 SSNS--------PETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAET 1308
Query: 242 VVEDERLHHDTDD-----VTYQVYEEQAVYEPLENE-GIEITEVTAPPEDN-----PVED 290
D+ D DD + EEQ E ++ E G++ + + A + + E+
Sbjct: 1309 AQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEE 1368
Query: 291 SQVIVEEVSIFPVEEQQEVPPETNRKTDDPEQKAKVKKKKPKLLNKFDKTIKAELDAAEK 350
+++ EE P + V + DD E+ + K++ +L + ++ +ELD
Sbjct: 1369 TELDSEEEQ--PSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEE-EEIPHSELDL--- 1422
Query: 351 LRKRGKIEEAVNAFKELVRKYPQSPRARYGKAQCEDDLA 389
E V A + L ++ Y CE+ LA
Sbjct: 1423 --------ETVQAVQSLTQEESSEHEGAY--QDCEETLA 1451
Score = 43.5 bits (101), Expect = 7e-04
Identities = 63/253 (24%), Positives = 98/253 (38%), Gaps = 49/253 (19%)
Query: 111 ERSTSEPAVPPEEAEPHT-----EPEEQVPV--EAEPQNIEDEAKEQIQSLLHEM----- 158
E T EP V EE +P + EE+ E EP+ ED A E Q+ H+
Sbjct: 1262 ETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDD 1321
Query: 159 VHAEHVEGEDLQQEDGPTGEPQQED----DEFLMATDVDDRFETLEPEVSHEETEHSYHV 214
H E + ++L+++ PT E +E+ + FL A R + + E + ++E
Sbjct: 1322 GHLESTKKKELEEQ--PTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSE----- 1374
Query: 215 EETVSQDCNQDMEEMM-SEQENPDSS-------EPVVEDERLHHDTDDVTYQVYEEQAVY 266
EE S D + E+M SE ++ + S E E+E H + D T Q +
Sbjct: 1375 EEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQE 1434
Query: 267 EPLENEGI---------------EITEVTAPPEDNPVEDSQVIVEEVSIFPVEEQQEVPP 311
E E+EG T+ P+ + VED P+ Q P
Sbjct: 1435 ESSEHEGAYQDCEETLAACQTLQSYTQADEDPQMSMVEDCHASEHN---SPISSVQSHPS 1491
Query: 312 ETNRKTDDPEQKA 324
++ R P A
Sbjct: 1492 QSVRSVSSPNVPA 1504
Score = 38.9 bits (89), Expect = 0.018
Identities = 49/203 (24%), Positives = 86/203 (42%), Gaps = 37/203 (18%)
Query: 113 STSEPAVPPEEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQSLLHEMVHAEHVEGEDLQQE 172
S+ PA P ++ E E + EP+ E+E K ++ E + E+ QQE
Sbjct: 1246 SSEVPAASPADSSNSPETETK-----EPEVEEEEEKPRVSE--------EQRQSEEEQQE 1292
Query: 173 DGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEETEHSYHVEET-----VSQDCNQDME 227
EP+ E++E D ET + + + E H+E T Q +D++
Sbjct: 1293 ---LEEPEPEEEE-------DAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDVK 1342
Query: 228 EMMSEQENPDSSEPVVEDERLHHDTDDVTYQVYEEQAVYEPLENEGIEITEVTAPPEDNP 287
E QE+ + E++ D ++ EEQ P + + ++E A ED+
Sbjct: 1343 EEPGVQESFLDANMQKSREKI-KDKEETELDSEEEQ----PSHDTSV-VSEQMAGSEDDH 1396
Query: 288 VEDSQVIVEEVSIFPVEEQQEVP 310
EDS E + ++E++E+P
Sbjct: 1397 EEDSHTKEE---LIELKEEEEIP 1416
>gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 55.8 bits (133), Expect = 1e-07
Identities = 66/279 (23%), Positives = 115/279 (41%), Gaps = 43/279 (15%)
Query: 122 EEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQSLLHEMVHAEHVEGEDLQQEDGPTGEPQQ 181
+E+E EP+E +P + +E KE+ + + E AE E ED + P P
Sbjct: 1205 QESEETVEPKEDMP-------LPEERKEE-EEMQAEAEEAEEGEEEDAASSEVPAASPAD 1256
Query: 182 EDDEFLMATDVDDRFETLEPEVSHEETEHSYHVEETVSQDCNQDMEEMMSEQENPDSSEP 241
+ ET EPEV EE + E+ S++ Q++EE E+E ++E
Sbjct: 1257 SSNS--------PETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAET 1308
Query: 242 VVEDERLHHDTDD-----VTYQVYEEQAVYEPLENE-GIEITEVTAPPEDN-----PVED 290
D+ D DD + EEQ E ++ E G++ + + A + + E+
Sbjct: 1309 AQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEE 1368
Query: 291 SQVIVEEVSIFPVEEQQEVPPETNRKTDDPEQKAKVKKKKPKLLNKFDKTIKAELDAAEK 350
+++ EE P + V + DD E+ + K++ +L + ++ +ELD
Sbjct: 1369 TELDSEEEQ--PSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEE-EEIPHSELDL--- 1422
Query: 351 LRKRGKIEEAVNAFKELVRKYPQSPRARYGKAQCEDDLA 389
E V A + L ++ Y CE+ LA
Sbjct: 1423 --------ETVQAVQSLTQEESSEHEGAY--QDCEETLA 1451
Score = 43.5 bits (101), Expect = 7e-04
Identities = 63/253 (24%), Positives = 98/253 (38%), Gaps = 49/253 (19%)
Query: 111 ERSTSEPAVPPEEAEPHT-----EPEEQVPV--EAEPQNIEDEAKEQIQSLLHEM----- 158
E T EP V EE +P + EE+ E EP+ ED A E Q+ H+
Sbjct: 1262 ETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDD 1321
Query: 159 VHAEHVEGEDLQQEDGPTGEPQQED----DEFLMATDVDDRFETLEPEVSHEETEHSYHV 214
H E + ++L+++ PT E +E+ + FL A R + + E + ++E
Sbjct: 1322 GHLESTKKKELEEQ--PTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSE----- 1374
Query: 215 EETVSQDCNQDMEEMM-SEQENPDSS-------EPVVEDERLHHDTDDVTYQVYEEQAVY 266
EE S D + E+M SE ++ + S E E+E H + D T Q +
Sbjct: 1375 EEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQE 1434
Query: 267 EPLENEGI---------------EITEVTAPPEDNPVEDSQVIVEEVSIFPVEEQQEVPP 311
E E+EG T+ P+ + VED P+ Q P
Sbjct: 1435 ESSEHEGAYQDCEETLAACQTLQSYTQADEDPQMSMVEDCHASEHN---SPISSVQSHPS 1491
Query: 312 ETNRKTDDPEQKA 324
++ R P A
Sbjct: 1492 QSVRSVSSPNVPA 1504
Score = 38.9 bits (89), Expect = 0.018
Identities = 49/203 (24%), Positives = 86/203 (42%), Gaps = 37/203 (18%)
Query: 113 STSEPAVPPEEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQSLLHEMVHAEHVEGEDLQQE 172
S+ PA P ++ E E + EP+ E+E K ++ E + E+ QQE
Sbjct: 1246 SSEVPAASPADSSNSPETETK-----EPEVEEEEEKPRVSE--------EQRQSEEEQQE 1292
Query: 173 DGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEETEHSYHVEET-----VSQDCNQDME 227
EP+ E++E D ET + + + E H+E T Q +D++
Sbjct: 1293 ---LEEPEPEEEE-------DAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDVK 1342
Query: 228 EMMSEQENPDSSEPVVEDERLHHDTDDVTYQVYEEQAVYEPLENEGIEITEVTAPPEDNP 287
E QE+ + E++ D ++ EEQ P + + ++E A ED+
Sbjct: 1343 EEPGVQESFLDANMQKSREKI-KDKEETELDSEEEQ----PSHDTSV-VSEQMAGSEDDH 1396
Query: 288 VEDSQVIVEEVSIFPVEEQQEVP 310
EDS E + ++E++E+P
Sbjct: 1397 EEDSHTKEE---LIELKEEEEIP 1416
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 54.7 bits (130), Expect = 3e-07
Identities = 78/350 (22%), Positives = 134/350 (38%), Gaps = 38/350 (10%)
Query: 1 MAQRKNAKSSGNSSSSGSGSGSTSAGSSSPGARRETKHGGHKNGRKGGLSGTSFFTWFMV 60
MAQ + K+ + +S+GS G R ET GG +G + L G +
Sbjct: 1768 MAQEREGKTHNSETSAGSELGEAEQEGEGISERGET--GGQGSGHEDNLQGEA------- 1818
Query: 61 IALLGVWTSVAVVWFDLVDYEEVLGKL-----GIYDADGDGDFDVDDAKVLLGLKERSTS 115
A G + ++ E G+ G+ + +GD + + + S
Sbjct: 1819 -AAGGDQDPGQSDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEA------QPES 1871
Query: 116 EPAVPPE---EAEPHTE----PEEQVPVEAEPQNIEDEAKEQIQSLLHEMVHAEHVEGED 168
E PE EA+P +E PE + V+ E + E E+ E V A EGED
Sbjct: 1872 EDVEAPEAEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGED 1931
Query: 169 LQQEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEETEHSYHVEETVSQDCNQDMEE 228
+ +G + +E + E +E + + EE + E + + E
Sbjct: 1932 EPESEGAEAQEAEEAAQEAEG-QTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAE 1990
Query: 229 MMSEQENPDSSEPVVE------DERLHHDTDDVTYQVYEEQAVYEPLENEGIEITEVTAP 282
++ E+ D P E +E ++D V Q E + +E E + TE A
Sbjct: 1991 GEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGE-TQKTEGDAQ 2049
Query: 283 PEDNPVEDSQVIVEEVSIFPVEEQQEVPPETNRKTDDPEQKAKVKKKKPK 332
PE + VE + EE + E QE E + +++D + + + +P+
Sbjct: 2050 PESDGVEAPE--AEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPE 2097
Score = 45.8 bits (107), Expect = 1e-04
Identities = 59/257 (22%), Positives = 106/257 (41%), Gaps = 34/257 (13%)
Query: 122 EEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQSLLHEMVHAEHVEGEDLQQEDGPTGEPQQ 181
+EAE T+PE +V E Q E+EA+ + + + E +E E QE +P+
Sbjct: 1948 QEAEGQTQPESEV---IESQEAEEEAQPESEDV-------EALEVEVETQEAEGEAQPES 1997
Query: 182 EDDEFLMAT-DVDDRFETLEPEVSHEETEHSYHVEETVSQDCNQDMEEMMSEQENPDSSE 240
ED E A ++ + E +PE E + EE + E ++ E+
Sbjct: 1998 EDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEA 2057
Query: 241 PVVEDE-------------RLHHDTDDVTYQVYEEQAVYEPLENEGIEITEVTAPPE--- 284
P E+E H +++DV Q E +A +P E+EG+E E +
Sbjct: 2058 PEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEA--QP-ESEGVEAPEAEGEAQKAE 2114
Query: 285 --DNPVEDSQVIVEEVSIFPVEEQQEVPPETNR-KTDDPEQKAKVKKKKPKLLNKFDKTI 341
+ P + + E I E + E PE+ + D E +A+ + + + + ++
Sbjct: 2115 GIEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIE-AQEAEEEA 2173
Query: 342 KAELDAAEKLRKRGKIE 358
+ EL+ E G+ +
Sbjct: 2174 QPELEGVEAPEAEGEAQ 2190
Score = 41.6 bits (96), Expect = 0.003
Identities = 49/210 (23%), Positives = 84/210 (40%), Gaps = 25/210 (11%)
Query: 118 AVPPEEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQSLLHEMVHAEHVEGEDLQQEDGPTG 177
A E E + EEQ N+E A+ +Q + E EGE LQ+E
Sbjct: 1268 ACATNEDEAERDSEEQ----RASSNLEQLAENTVQEEVQLEETKEGTEGEGLQEEAVQLE 1323
Query: 178 EPQQEDDEFLMATDVDDRFETLEPEVSHEETEHSYHVEETVSQDCNQDMEEMMSEQENPD 237
E + E+ +++ ET E E EE +EET + ++ ++ +E P+
Sbjct: 1324 ETKTEEGLQEEGVQLEETKET-EGEGQQEEEAQLEEIEETGGEGLQEEGVQLEEVKEGPE 1382
Query: 238 SSEPVVEDERLHHDTDDVTYQVYEEQAVYEPLENEGIEITEVTAP-----PEDNPVEDSQ 292
++ E L + +E+ + E G E++E ++P ED+PV++ +
Sbjct: 1383 GG---LQGEALE--------EGLKEEGLPEEGSVHGQELSEASSPDGKGSQEDDPVQEEE 1431
Query: 293 VIVEEVSIFPV----EEQQEVPPETNRKTD 318
S P E+ PP +TD
Sbjct: 1432 AGRASASAEPCPAEGTEEPTEPPSHLSETD 1461
Score = 39.3 bits (90), Expect = 0.014
Identities = 60/256 (23%), Positives = 94/256 (36%), Gaps = 34/256 (13%)
Query: 93 DGDGDFDVDDAKVLLGLKERSTSEPAVPPEEAEPHTEPE----EQVPVEAEPQNIEDEAK 148
+GD + D + +E +E V E E H E E ++ EA+P++ EA
Sbjct: 2045 EGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAP 2104
Query: 149 E-QIQSLLHEMVHAEHVEGEDLQQEDG-----PTGEPQQEDDEFLMATDVDDRFETLEPE 202
E + ++ E + A EGE + +G GE Q E + + D +PE
Sbjct: 2105 EAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESE----GVEAQDAEGEAQPE 2160
Query: 203 VSHEETEHSYHVEETVSQDCNQDMEEMMSEQENPDSSEPVVEDERLHHDTDDVTYQVYEE 262
E + + + + E ++ E+ P E E + + V EE
Sbjct: 2161 SEGIEAQEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGE-AQPELEGVEAPEAEE 2219
Query: 263 QAVYEPLENEGIEITEV--TAPPEDN-------------PVEDSQVIVEEVSIFPVEEQQ 307
+A EP EG+E E A PE + D Q S PV E +
Sbjct: 2220 EAQPEP---EGVETPEAEGEAQPESEGETQGEKKGSPQVSLGDGQSEEASESSSPVPEDR 2276
Query: 308 EVPPETNRKTDDPEQK 323
PP + D P Q+
Sbjct: 2277 PTPP-PSPGGDTPHQR 2291
Score = 32.3 bits (72), Expect = 1.7
Identities = 41/162 (25%), Positives = 61/162 (37%), Gaps = 39/162 (24%)
Query: 111 ERSTSEPAVPPEEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQS----------------- 153
E E V EE + TE E Q EA+ + IE+ E +Q
Sbjct: 1328 EEGLQEEGVQLEETK-ETEGEGQQEEEAQLEEIEETGGEGLQEEGVQLEEVKEGPEGGLQ 1386
Query: 154 --LLHEMVHAE------HVEGEDLQQEDGPTGEPQQEDDEFLMATDVDDRFETLEP---E 202
L E + E V G++L + P G+ QEDD + + + EP E
Sbjct: 1387 GEALEEGLKEEGLPEEGSVHGQELSEASSPDGKGSQEDDP-VQEEEAGRASASAEPCPAE 1445
Query: 203 VSHEETEHSYHVEETVSQDCNQDMEEMMSEQENPDSSEPVVE 244
+ E TE H+ ET + SE+++ EP +E
Sbjct: 1446 GTEEPTEPPSHLSET---------DPSASERQSGSQLEPGLE 1478
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 50.4 bits (119), Expect = 6e-06
Identities = 81/328 (24%), Positives = 136/328 (41%), Gaps = 35/328 (10%)
Query: 117 PAVP----PEEAEPHTEPEE------QVPVEAEPQNIEDEAKEQIQSLLHEMVHAEHVEG 166
P VP PEE +P P++ +VP + EP + ++ + L E + E
Sbjct: 10061 PEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEE--- 10117
Query: 167 EDLQQEDGPTGEPQQ---EDDEFLMATD-VDDRFETLEPEVSHEETEHSYHVEETVSQDC 222
E L +E+ E ++ E++E L + + E + PE + E + EE V +
Sbjct: 10118 EVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPEEEVLPEV 10177
Query: 223 NQDME--EMMSEQENPDSSEPVV---EDERLHHDTDDVTYQVYEEQAVYEPLENEGIEIT 277
+ + E + + + VV ++E +V +V EE+ + P E E + +
Sbjct: 10178 KPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKV-EEKRIILPKEEEVLPV- 10235
Query: 278 EVTAPPEDNPVEDSQVIVEEVSIFPVEEQQEVPPETNR--KTDDPEQKAKVKKKKPKLLN 335
EVT PE+ P+ + ++ E SI VEE PP K PE V KK
Sbjct: 10236 EVTEEPEEEPISEEEIPEEPPSIEEVEE--VAPPRVPEVIKKAVPEAPTPVPKKVEAPPA 10293
Query: 336 KFDKTI---KAELDAAEKLRKRGKIEEA---VNAFKELVRKYPQSPRARYGKAQCEDDLA 389
K K I K + +K K+ E V K LV K P A+ G+ E+ ++
Sbjct: 10294 KVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVLVPKKEAVPPAK-GRTVLEEKVS 10352
Query: 390 EKRRSNEVLRGAIETYQEVASLPDVPAD 417
R V++ +E A + ++P +
Sbjct: 10353 VAFRQEVVVKERLELEVVEAEVEEIPEE 10380
Score = 49.7 bits (117), Expect = 1e-05
Identities = 65/270 (24%), Positives = 115/270 (42%), Gaps = 37/270 (13%)
Query: 100 VDDAKVLLGLKERSTSEPAVP-------PEEAEPHTEPEEQVP----VEAEPQNIEDEAK 148
V + K+ + + + PAVP PEE +P EE+VP V A P+ E K
Sbjct: 9380 VTEEKITIVTQREESPPPAVPEIPKKKVPEERKPVPRKEEEVPPPPKVPALPKKPVPEEK 9439
Query: 149 EQIQSLLHEMVHAEHVEGEDLQQEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEET 208
+ + + E E ++ E ++ V R E EVS EE
Sbjct: 9440 VAVPVPVAKKAPPPRAE-----VSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEVSAEEE 9494
Query: 209 EHSYHVEETVS------QDCNQDMEEMMSEQENPDSSEPVVEDERLH-------HDTDDV 255
EE VS ++ ++ E ++E E + E V +E+LH + +V
Sbjct: 9495 WSYSEEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVEAEPAEV 9554
Query: 256 TYQVYEEQAVYEPLENEGIEITEVTAPPEDNPVEDSQVIVEEVSIFPVEEQQEVPPETNR 315
T + E++ V +P IE PP P +++ E+ PV ++++VPP +
Sbjct: 9555 TER-QEKKIVLKPKIPAKIE----EPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPP--K 9607
Query: 316 KTDDPEQKAKVKKKKPKLLNKFDKTIKAEL 345
++P++ KK PK++ K ++ + A++
Sbjct: 9608 VPEEPKKPVPEKKVPPKVI-KMEEPLPAKV 9636
Score = 44.3 bits (103), Expect = 4e-04
Identities = 56/237 (23%), Positives = 96/237 (40%), Gaps = 40/237 (16%)
Query: 106 LLGLKERSTSEPAVPPEEAEPHTEPEEQVPVEA---EPQNIED----EAKEQIQSLLHEM 158
+L LK + EP E EE+V +EA EPQ I++ E KE+ +L E
Sbjct: 9677 VLKLKPKREEEPPAKVTEFRKRVVKEEKVSIEAPKREPQPIKEVTIMEEKERAYTLEEEA 9736
Query: 159 VHAEHVEG-EDLQQEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEETEHSYHVEET 217
V + E E+ ++ D E + +E+ D++E +EE E+ + E
Sbjct: 9737 VSVQREEEYEEYEEYDYKEFEEYEPTEEY-------DQYE------EYEEREYERYEEH- 9782
Query: 218 VSQDCNQDMEEMMSEQENPDSSEPVVED---ERLHHDTDDVTYQVYEEQAVYEPLENEGI 274
EE ++E E P +PV E+ + V + E+ V P+
Sbjct: 9783 ---------EEYITEPEKPIPVKPVPEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPK--- 9830
Query: 275 EITEVTAPPEDNPVEDSQVIVEEVSIFPVEEQQEVPPETNRKTDDPEQKAKVKKKKP 331
++ PP P E +V E++ I + ++E E K ++ ++K P
Sbjct: 9831 ---KLKPPPPKVPEEPKKVFEEKIRISITKREKEQVTEPAAKVPMKPKRVVAEEKVP 9884
Score = 42.7 bits (99), Expect = 0.001
Identities = 58/263 (22%), Positives = 99/263 (37%), Gaps = 59/263 (22%)
Query: 123 EAEPHTEPEEQVPVEAEPQNIEDEAKEQIQSLLHEMVHAEHVEGEDLQQEDGPTGEPQQE 182
E EP+TEP EQ P EP +E K + + +HE + EG++ + + E ++E
Sbjct: 9081 EVEPYTEPFEQ-PYYEEPDEDYEEIKVEAKKEVHEEWEEDFEEGQEYYEREEGYDEGEEE 9139
Query: 183 DDEFLMATDVDDRFETLEPEVSHEETEHSY------------------HVEETVSQDCNQ 224
+E +V ++ EV E E V E + + +
Sbjct: 9140 WEEAYQEREVIQ----VQKEVYEESHERKVPAKVPEKKAPPPPKVIKKPVIEKIEKTSRR 9195
Query: 225 DMEEMMSEQENPDSSEP----------------------------VVEDERL---HHDTD 253
EE + + P+ S+ V+ +E++ H +
Sbjct: 9196 MEEEKVQVTKVPEVSKKIVPQKPSRTPVQEEVIEVKVPAVHTKKMVISEEKMFFASHTEE 9255
Query: 254 DVTYQVYEEQAVYEPLENEGIEITEVTAPPEDNPVEDSQVIVEEVSIFPVEEQQEVP--- 310
+V+ V E Q E + I++ PP P + EEV+ P+ ++ E P
Sbjct: 9256 EVSVTVPEVQKEIVTEEKIHVAISKRVEPPPKVPELPEKPAPEEVAPVPIPKKVEPPAPK 9315
Query: 311 -PETNRKTDDPEQK-AKVKKKKP 331
PE +K E+K V KK+P
Sbjct: 9316 VPEVPKKPVPEEKKPVPVPKKEP 9338
Score = 42.0 bits (97), Expect = 0.002
Identities = 66/276 (23%), Positives = 111/276 (40%), Gaps = 26/276 (9%)
Query: 116 EPAVPP---EEAEPHTEPEEQVPV------EAEPQNIEDEAKEQIQSLLHEMVHAEHVEG 166
+P +PP E PE++VP+ EA P + + KE + + V
Sbjct: 10713 KPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPP 10772
Query: 167 EDLQQEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEETEHSYHVEETVSQDCNQDM 226
+ + P++ E A V +R E+ PEV +EE E EE ++ +
Sbjct: 10773 AKVPEV------PKKPVLEEKPAVPVPERAESPPPEV-YEEPEEIAPEEEIAPEE---EK 10822
Query: 227 EEMMSEQENPDSSEPVVEDE--RLHHDTDDVTYQVYEEQAVYEPLENEGIEITEVTA--- 281
++E+E P+ P V +E ++ + + E EP + IE ++
Sbjct: 10823 PVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPP 10882
Query: 282 -PPEDNPVEDSQVIVEEVSIFPVEEQQEVPPETNRKTDDPEQKAKVKKKKPKLLNKFDKT 340
PP P ED + + ++ P ++ E P + P + +KK KLL +
Sbjct: 10883 PPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPE 10942
Query: 341 IKAELDAAEKLRKRGKIEEAVNAFKELVR-KYPQSP 375
K E+ LRKR + EE K+L + K P P
Sbjct: 10943 PKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVP 10978
Score = 38.1 bits (87), Expect = 0.031
Identities = 51/248 (20%), Positives = 91/248 (36%), Gaps = 45/248 (18%)
Query: 110 KERSTSEPAVPPEEAEPHTEPEEQVPV------EAEPQNIEDEAKEQIQSLLHEMVHAEH 163
+E ++P PP + PEE+VPV + P + +E K+ + + +
Sbjct: 9800 EEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKLKPPPPKVPEEPKKVFEEKIRISITKRE 9859
Query: 164 VEGEDLQQEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEETEHSYHVEETV-SQDC 222
E Q P + + + V + + P V E EE ++
Sbjct: 9860 KE-----QVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPKELEPEEVAFEEEV 9914
Query: 223 NQDMEEMMSEQENPDSSEPVVEDERLHHDTDDVTYQVYEEQAVYEPLENEGIEITEVTAP 282
+EE + E+ E+E +H + + +T E+ V + + E+ P
Sbjct: 9915 VTHVEEYLVEE----------EEEYIHEEEEFIT-----EEEVVPVIPVKVPEVPRKPVP 9959
Query: 283 PEDNPVEDSQVIVEEVSIFPVEEQQEVPPETNRKTDDPEQKAKVKKKKPKLLNKFDKTIK 342
E PV PV +++E PP PE K ++K P L+ K +K
Sbjct: 9960 EEKKPV-------------PVPKKKEAPP-----AKVPEVPKKPEEKVPVLIPKKEKPPP 10001
Query: 343 AELDAAEK 350
A++ K
Sbjct: 10002 AKVPEVPK 10009
Score = 31.6 bits (70), Expect = 2.9
Identities = 51/243 (20%), Positives = 95/243 (39%), Gaps = 25/243 (10%)
Query: 100 VDDAKVLLGLKERS---TSEPAVPPEEAEPHTEPEEQVPVE----AEPQNIEDEAKE-QI 151
V + K+ + + +R +EPA EE+VPV A P + + KE +
Sbjct: 9846 VFEEKIRISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPKELEP 9905
Query: 152 QSLLHEMVHAEHVEGEDLQQEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEETEHS 211
+ + E HVE +++E+ E E++EF+ +V PEV +
Sbjct: 9906 EEVAFEEEVVTHVEEYLVEEEE----EYIHEEEEFITEEEVVPVIPVKVPEVPRKPVPEE 9961
Query: 212 YHVEETVSQDCNQDMEEMMSEQENPDSSEPVV---EDERLHHDTDDVTYQVYEEQAVYEP 268
V + ++ + P+ PV+ +++ +V + E+ V P
Sbjct: 9962 KK-PVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVP 10020
Query: 269 LENEGIEITEVTAPPEDNPVEDSQVIVEEVSIFPVEEQQEVPPETNRKTDDPEQKAKVKK 328
+ + V APP P + + E+ P ++ E PP K + +K ++
Sbjct: 10021 VPKK------VEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPP---AKVPEVPKKLIPEE 10071
Query: 329 KKP 331
KKP
Sbjct: 10072 KKP 10074
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 50.4 bits (119), Expect = 6e-06
Identities = 55/282 (19%), Positives = 122/282 (43%), Gaps = 21/282 (7%)
Query: 122 EEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQSLLHEMVHAEHV---EGEDLQQEDGPTGE 178
EE + H + ++ +E EPQ E ++Q++ E EGE+ Q
Sbjct: 1632 EEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDR 1691
Query: 179 PQQEDDEFLMATDVDDRFETLEPEVSHEETEHSYHVEETVSQDCNQDM---EEMMSEQEN 235
+E+++ L + + +F E ++ +E E + EE + Q+ Q+ +E +
Sbjct: 1692 KFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILE 1751
Query: 236 PDSSEPVVEDERLHHDTDDVTYQVYEEQAVYEPLENEGIEITEVTAPPEDNPVEDSQVIV 295
+ P E+++L D ++ EE+ + + E + + E D + + +
Sbjct: 1752 EEQLRPEREEQQLRRQERDRKFR--EEEQLRQEREEQQLRSQE-----SDRKFREEEQLR 1804
Query: 296 EEVSIFPVEEQQEVPPETNRKTDDPEQKAKVKKKKPKLLNKFDKTIKAELDAAEKLRKRG 355
+E EEQQ P + + K E++ ++++++ +L + D+ +AE A + + R
Sbjct: 1805 QER-----EEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRR 1859
Query: 356 KIEEAVNAFKELVRKYPQSPRARYGKAQCEDDLAEKRRSNEV 397
+ +E ++E +K Q + + E++R +V
Sbjct: 1860 EEQE---LWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQV 1898
Score = 47.0 bits (110), Expect = 7e-05
Identities = 67/318 (21%), Positives = 134/318 (42%), Gaps = 35/318 (11%)
Query: 122 EEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQSLLHEMVHAEHVEGEDLQQEDGPTGEPQQ 181
+E E + EE+ + Q + +EQ+Q E E L +E+ Q+
Sbjct: 907 QEEEEELQREEREKRRRQEQERQYREEEQLQQ-----------EEEQLLREEREKRRRQE 955
Query: 182 EDDEFLMATDVDDRFETL---EPEV-SHEETEHSYHVEETVSQDCNQDMEEMMSEQENPD 237
+ ++ + + E L EPE +E E Y EE + Q+ Q + E ++
Sbjct: 956 RERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQ- 1014
Query: 238 SSEPVVEDERLHHDTDDVTYQVYEEQAVYEPLENEGIEITEVTAPPEDN-PVEDSQVIVE 296
E ER + D++ Q EEQ + E E ++ E E+ E+ Q++ E
Sbjct: 1015 ------EWERQYRKKDEL--QQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGE 1066
Query: 297 EVSIFPVEEQQEVPPETNRKTDDPEQKAKVKKKKP--KLLNKFDKTIKAELDAAEKLRKR 354
E +QE+ + ++ + +++ ++ +++P + + ++ + E + ++ +
Sbjct: 1067 ERE---TRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQL 1123
Query: 355 GKIEEAVNAFKELVRKYPQSPRARYGKAQCEDDLAEKRRSNEVLRGAIETYQEVASLPDV 414
+ E +EL R+Y + + + Q + EKRR E+ R Y+E L
Sbjct: 1124 LREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELER----QYREEEELQQE 1179
Query: 415 PADLLKLSL-KRRSDRQQ 431
LL+ KRR +R++
Sbjct: 1180 EEQLLREEQEKRRQERER 1197
Score = 43.1 bits (100), Expect = 0.001
Identities = 59/289 (20%), Positives = 123/289 (42%), Gaps = 23/289 (7%)
Query: 122 EEAEPHTEPEEQVPVEAEPQNIEDEAKE-QIQSLLHEMVHAEHVEGEDLQQEDGPTGEPQ 180
EE + + ++ E E ++ E E K + + LH E+ Q G+ +
Sbjct: 1490 EEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQR 1549
Query: 181 QEDDEFLMATDVDDRFETLEPEVSHEETEHSYHVEETVSQDCNQDMEEMMSEQE------ 234
++D + + R E E ++S +E + + +EE + Q+ + M EQ+
Sbjct: 1550 RQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEG 1609
Query: 235 ----NPDSSEPVVEDERLHHDTDDVTYQVYEEQAVYEPLENEGIEITEVTAPPEDNPVED 290
+ EDE+L + ++ Q++ ++ + LE E ++ + D
Sbjct: 1610 QQQLRQERDRKFREDEQLLQEREE--QQLHRQERDRKFLEEEP-QLRRQEREQQLRHDRD 1666
Query: 291 SQVIVEEVSIFPVEEQQEVPPETNRKTDDPEQKAKVKKKKPKLLNKFDKTIKAELDAAEK 350
+ EE + EEQQ E +RK + EQ+ + ++++ K L + + + EL+ K
Sbjct: 1667 RKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELE--RK 1724
Query: 351 LRKRGKIEEAVNAFKELVRKYPQSPRARYGKAQCEDDLAEKRRSNEVLR 399
R+ ++ + +E +R+ + RY K E+ L +R ++ R
Sbjct: 1725 FREEEQLRQETE--QEQLRR-----QERYRKILEEEQLRPEREEQQLRR 1766
Score = 38.9 bits (89), Expect = 0.018
Identities = 66/335 (19%), Positives = 132/335 (39%), Gaps = 34/335 (10%)
Query: 107 LGLKERSTSEPAVPPEEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQSLLHEMVHAEHVEG 166
L +ER E PEE E ++ E E Q +E+E EQ+Q
Sbjct: 798 LRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEE--EQLQ---------RRERA 846
Query: 167 EDLQQEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEETEHSYHVEETVSQDCNQDM 226
+ LQ+E+ E Q+ D R++ E + H+ + + + + ++
Sbjct: 847 QQLQEEEDGLQEDQERRRSQEQRRDQKWRWQL---EEERKRRRHTLYAKPALQEQLRKEQ 903
Query: 227 EEMMSEQENPDSSEPV----VEDERLHHDTDDVTYQVYEEQAVYEPLENEGIEITEVTAP 282
+ + E+E E E ER + + + + Q EEQ + E E + E
Sbjct: 904 QLLQEEEEELQREEREKRRRQEQERQYREEEQL--QQEEEQLLREEREKRRRQERERQYR 961
Query: 283 PEDN-PVEDSQVIVEEVSIFPVEEQQEVPPETNRKTDDPEQ---KAKVKKKKPKLLNKFD 338
+ ++ Q++ EE +E+++ E + EQ + + K+++ + ++
Sbjct: 962 KDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYR 1021
Query: 339 KTIKAELDAAEKLRKRGKIEEAVNAFKELVRKYPQSPRARYGKAQCEDDLAEKRRSNEVL 398
K + + + + LR+ E +E R+Y + + + Q + E RR E+
Sbjct: 1022 KKDELQQEEEQLLRE----EREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELE 1077
Query: 399 RGAIETYQEVASLPDVPADLLK--LSLKRRSDRQQ 431
R Y++ L LL+ +RR +R++
Sbjct: 1078 R----QYRKEEELQQEEEQLLREEPEKRRRQERER 1108
Score = 36.2 bits (82), Expect = 0.12
Identities = 59/304 (19%), Positives = 125/304 (41%), Gaps = 28/304 (9%)
Query: 102 DAKVLLG-LKERSTSEPAVPPEEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQSLLHEMVH 160
D + LLG +ER + ++ + H EEQ+ E + + + K Q + +++
Sbjct: 1266 DLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEK---QLLR 1322
Query: 161 AEHVEGEDLQQEDGPTGEPQQ----EDDEFLMATDVDDRFETLEPEVSHEETEHSYHVEE 216
E E Q+ D E +Q +++ L + D +F E E+ H+E + EE
Sbjct: 1323 EEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFR--EEELRHQEQGRKFLEEE 1380
Query: 217 TVSQDCNQDMEEMMSEQENPDSSEPVVEDERLHHDTDDVTYQVYEEQAVYEPLENEGIEI 276
+ ++ + + EQ+ +++L D D ++ E+Q + + + E
Sbjct: 1381 QRLRRQERERKFLKEEQQLRCQER----EQQLRQDRDR-KFREEEQQLSRQERDRKFRE- 1434
Query: 277 TEVTAPPEDNPVEDSQVIVEEVSIFPVEEQQEVPPETNRKTDDPEQKAKVKKKKPKLLNK 336
E+ QV +E +EE+Q++ E +RK + EQ + ++++ +
Sbjct: 1435 ------------EEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQE 1482
Query: 337 FDKTIKAELDAAEKLRKRGKIEEAVNAFKELVRKYPQSPRARYGKAQCEDDLAEKRRSNE 396
D+ E + + K E +E RK+ + + + + + L E+++
Sbjct: 1483 RDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRR 1542
Query: 397 VLRG 400
RG
Sbjct: 1543 QERG 1546
Score = 35.8 bits (81), Expect = 0.15
Identities = 44/225 (19%), Positives = 91/225 (40%), Gaps = 29/225 (12%)
Query: 122 EEAEPHTEPEEQVPVEAEPQNIE---------DEAKEQIQSLLHEMVHAEHVEGEDLQQE 172
EE E E E+ + E E + + DE +++ + LL E ++ + Q
Sbjct: 992 EEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYR 1051
Query: 173 DGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEETEHSYHVEETVSQDCNQDMEEMMSE 232
+ E Q+++E L+ + + R +E E Y EE + Q+ Q + E +
Sbjct: 1052 EE---EELQQEEEQLLGEERETR--------RRQELERQYRKEEELQQEEEQLLREEPEK 1100
Query: 233 QENPDSSEPVVEDERLHHDTDDVTYQVYEEQAVYEPLENEGIEITEVTAP--------PE 284
+ + E+E L + + + + E++ E LE + E EV PE
Sbjct: 1101 RRRQERERQCREEEELQQEEEQLLREEREKRRRQE-LERQYREEEEVQQEEEQLLREEPE 1159
Query: 285 DNPVEDSQVIVEEVSIFPVEEQQEVPPETNRKTDDPEQKAKVKKK 329
++ + E EE+Q + E ++ + E++ + +++
Sbjct: 1160 KRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEE 1204
Score = 33.5 bits (75), Expect = 0.75
Identities = 55/299 (18%), Positives = 125/299 (41%), Gaps = 36/299 (12%)
Query: 125 EPHTEPEEQVPVEAEPQNIEDEAKEQIQSLLHEMVHAEHVEGEDLQQEDGPTGEPQQEDD 184
E E+Q+ E + + + +EQ ++ + + E Q+E+ + +QE
Sbjct: 386 EQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE--QEEERHEQKHEQERR 443
Query: 185 EFLMATDVDDRFETLEPEVSHEETEHSYHVEETVSQDCNQDMEE-------MMSEQENPD 237
E + + ++R + L+ E EETE H +E Q +D EE + E+E +
Sbjct: 444 EQRLKREQEERRDWLKRE---EETER--HEQERRKQQLKRDQEEERRERWLKLEEEERRE 498
Query: 238 SSEPVVEDERLHHDTDDVTYQVYEEQAVYEPLENEGIEITEVTAPPEDN-----PVEDSQ 292
E +++L + ++ Q + Q E L+ ++ E+ E+ +
Sbjct: 499 QQER--REQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEK 556
Query: 293 VIVEEVSIFPVEEQQEVPPETNRKTDDPEQKAKVKKKKPKLL---------------NKF 337
+ +E ++ +QE + K ++ ++ ++K+++ + L +
Sbjct: 557 RLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERR 616
Query: 338 DKTIKAELDAAEKLRKRGKIEEAVNAFKELVRKYPQSPRARYGKAQCEDDLAEKRRSNE 396
++ +K E E+ ++ K EE ++ +R+ Q R + K + E++ E+R E
Sbjct: 617 EQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKRE 675
>gi|17975763 myelin transcription factor 1 [Homo sapiens]
Length = 1121
Score = 49.3 bits (116), Expect = 1e-05
Identities = 52/232 (22%), Positives = 96/232 (41%), Gaps = 24/232 (10%)
Query: 119 VPPEEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQSLLHEMVHAEHVEGEDLQQEDGPTGE 178
+ PE+AE E + + PQ++ED A E+ + H E E E+ ++E+ E
Sbjct: 216 IQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDE 275
Query: 179 PQQEDDEFLMATDVDDRFETLEPEVSHEETEHSYHV--EETVSQDCNQDMEEMMS-EQEN 235
++E++E + ++ E E E EE E + V +E S Q E+ E +
Sbjct: 276 EEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPS 335
Query: 236 PDSSEPVVEDERLHHDTDDVTYQ----VYEEQAVYEPLENEGIEITE-----------VT 280
P V+ + R D D+ T+ V +E + + + + + E
Sbjct: 336 PKPEYSVIVEVRSDDDKDEDTHSRKSTVTDESEMQDMMTRGNLGLLEQAIALKAEQVRTV 395
Query: 281 APPEDNPVEDSQVIVEEVSIFPVEEQQEVPPETNRKTDDPEQKAKVKKKKPK 332
P P E SQ+ + E + P +T RK+ + ++ +K++ K
Sbjct: 396 CEPGCPPAEQSQLGLGEPG------KAAKPLDTVRKSYYSKDPSRAEKREIK 441
Score = 32.0 bits (71), Expect = 2.2
Identities = 36/192 (18%), Positives = 70/192 (36%), Gaps = 15/192 (7%)
Query: 158 MVHAEHVEGEDLQQEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEETEHSYHVEET 217
+VH E E+G G Q +D + +R + L P+ + ++
Sbjct: 194 IVHLLQEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKG 253
Query: 218 VSQDCNQDMEEMMSEQENPDSSEPVVEDERLHHDTDDVTYQVYEEQAVYEPLE------- 270
+ +D EE E+E + E E+E + ++ + EE+ E E
Sbjct: 254 ILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIF 313
Query: 271 ------NEGIEITEVTAPPEDNPVEDSQVIVEEVSIFPVEEQQEVPPETNRKTDDPEQKA 324
+ E+ P +P + VIVE S ++ ++ + TD+ E +
Sbjct: 314 QEDTSHTSAQKAPELRGPESPSPKPEYSVIVEVRS--DDDKDEDTHSRKSTVTDESEMQD 371
Query: 325 KVKKKKPKLLNK 336
+ + LL +
Sbjct: 372 MMTRGNLGLLEQ 383
Score = 32.0 bits (71), Expect = 2.2
Identities = 35/169 (20%), Positives = 60/169 (35%), Gaps = 10/169 (5%)
Query: 100 VDDAKVLLGLKERSTSEPAVPPEEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQSLLHEMV 159
++DA K++ EE E E EE+ E E + E+E +E+
Sbjct: 240 LEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEE--------- 290
Query: 160 HAEHVEGEDLQQEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEETEHSYHVEETVS 219
E E E+ ++E+ P E T E PE + E+S VE
Sbjct: 291 -EEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPEYSVIVEVRSD 349
Query: 220 QDCNQDMEEMMSEQENPDSSEPVVEDERLHHDTDDVTYQVYEEQAVYEP 268
D ++D S + + ++ L + + + + V EP
Sbjct: 350 DDKDEDTHSRKSTVTDESEMQDMMTRGNLGLLEQAIALKAEQVRTVCEP 398
>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
[Homo sapiens]
Length = 2073
Score = 49.3 bits (116), Expect = 1e-05
Identities = 74/326 (22%), Positives = 129/326 (39%), Gaps = 37/326 (11%)
Query: 112 RSTSEPAVPPEE---------AEPHTEPEEQVPVEAEPQNIEDEAKEQIQSLLHEMVHAE 162
+ T E +P EE P+T P E+ P + + E+E +E+ + E E
Sbjct: 1312 KETGEALLPQEENRREETCAPVSPNTSPGEK-PEDDLIKPEEEEEEEEEEEEEEEEEEGE 1370
Query: 163 HVEGEDLQQEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEETEHSYHVEE---TVS 219
EG ++D P G QE +E ++T+ +D + E EE E H E+
Sbjct: 1371 EEEGGGNVEKD-PDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDE 1429
Query: 220 QDCNQDMEEMMSEQENPDSSEPVVEDERLHHDTDDVTYQVYEEQAVYEPLENEGIEITEV 279
D + + E+ E+ +S + V+E++ D + V + E L + G+++T
Sbjct: 1430 DDSHMESAEVEKEELPRESFKEVLENQETFLDLN-----VQPGHSNPEVLMDCGVDLTAS 1484
Query: 280 TAPPEDNPVEDSQVIVEEVSIFPVEEQQEVPPETNRKTDDPEQKAKVKKKKPKLLNKFDK 339
D + + E P EQ + + N K D E K+ P + +
Sbjct: 1485 CNSEPKELAGDPEAVPESDEEPPPGEQAQKQDQKNSKEVDTE----FKEGNPATMEIDSE 1540
Query: 340 TIKAELDAAEKLRKR-------GKIEEAVNAFKELVRKYPQSPRARYGKAQCEDDLAEKR 392
T++A ++ ++ + +EA + + R QSP+ A DD +
Sbjct: 1541 TVQAVQSLTQESSEQDDTFQDCAETQEACRSLQNYTRA-DQSPQI----ATTLDDCQQSD 1595
Query: 393 RSNEVLRGAIETYQEVASL--PDVPA 416
S+ V Q V S+ P VPA
Sbjct: 1596 HSSPVSSVHSHPGQSVRSVNSPSVPA 1621
Score = 33.5 bits (75), Expect = 0.75
Identities = 35/140 (25%), Positives = 60/140 (42%), Gaps = 11/140 (7%)
Query: 203 VSHEETEHSYHVEETVSQ-DC-NQDMEEMMSEQENPDSSEPVVEDERLHHDTDDVTYQVY 260
VS EE E E + Q C ++ +E++S + N S V+ + + + + + V
Sbjct: 997 VSEEEREAEKEAERLMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPE-SRPVT 1055
Query: 261 EEQAVYEPLENEGIEITEVTAPPEDNPVEDSQVIVEEVSIFPVEEQQEVPPETNRKTDDP 320
E+ L E E E E+ E+ + EE EE++E E N ++ P
Sbjct: 1056 GERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEE----EEEEEEEEEENIQSSPP 1111
Query: 321 E----QKAKVKKKKPKLLNK 336
Q +K+K+P +L K
Sbjct: 1112 RLTKPQSVAIKRKRPFVLKK 1131
Score = 32.3 bits (72), Expect = 1.7
Identities = 18/48 (37%), Positives = 25/48 (52%)
Query: 106 LLGLKERSTSEPAVPPEEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQS 153
LL L + S+ E +E E E EE+ E E + E+E +E IQS
Sbjct: 1061 LLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQS 1108
Score = 31.6 bits (70), Expect = 2.9
Identities = 28/130 (21%), Positives = 53/130 (40%), Gaps = 17/130 (13%)
Query: 110 KERSTSEPAVPPEEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQSLLHEMVHAEHVEGEDL 169
KE + AVP + EP + Q + + ++ E KE + + ++ E +
Sbjct: 1490 KELAGDPEAVPESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPATM-------EIDSETV 1542
Query: 170 QQEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEETEHSYHVEETVSQDCNQDMEEM 229
Q T E ++DD F + + +L+ ++ + S + T+ DC Q
Sbjct: 1543 QAVQSLTQESSEQDDTFQDCAETQEACRSLQ---NYTRADQSPQIATTL-DDCQQ----- 1593
Query: 230 MSEQENPDSS 239
S+ +P SS
Sbjct: 1594 -SDHSSPVSS 1602
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 49.3 bits (116), Expect = 1e-05
Identities = 73/314 (23%), Positives = 126/314 (40%), Gaps = 42/314 (13%)
Query: 93 DGDGDFDVDDAKVLLGLKERSTSEPAVPPEEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQ 152
D +GD D K G KE E P +A E ++ E + + E +E+I+
Sbjct: 308 DNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIK 367
Query: 153 SLLHEMVHAEHVEGEDLQQEDGPTGEPQQEDDE--------------------------F 186
L E + A+ E E L+QE + ++++ +
Sbjct: 368 RL--EELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKL 425
Query: 187 LMATDVDDRFETLEPEVS--HEETEHSYHVEETVSQDCNQDME-----EMMSEQENPDSS 239
L A V+ + P+ +E+ + ++ S++ ++ ME E+M EQ P+
Sbjct: 426 LQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVM-EQGVPEKE 484
Query: 240 E--PVVEDERLHHDTDDVTYQVYEEQAVYEPLENEGIEITEVTAPPEDNPVEDSQVIVEE 297
E P VE E DT+D +E A E E E +E +V ++NP E+ + EE
Sbjct: 485 ETPPPVEPEE-EEDTEDAGLDDWEAMASDE--ETEKVEGNKVHIEVKENPEEEEEEEEEE 541
Query: 298 VSIFPVEEQQEVPPET-NRKTDDPEQKAKVKKKKPKLLNKFDKTIKAELDAAEKLRKRGK 356
EE++E E+ + D+ ++K +K K L+K + + R K
Sbjct: 542 EEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRTK 601
Query: 357 IEEAVNAFKELVRK 370
E A + K + K
Sbjct: 602 EERAYDKAKRRIEK 615
Score = 38.5 bits (88), Expect = 0.023
Identities = 34/153 (22%), Positives = 62/153 (40%), Gaps = 21/153 (13%)
Query: 108 GLKERSTSEPAVPPEEAEPHTEP---------EEQVPVEAEPQNIEDEAKEQIQSLLHEM 158
G+ E+ + P V PEE E + ++ + E + E KE + E
Sbjct: 479 GVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEE 538
Query: 159 VHAEHVEGEDLQQEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEETEHSYHVEETV 218
E E + ++E+ E + D+E +D D +TL+ + S E +
Sbjct: 539 EEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKE-----------M 587
Query: 219 SQDCNQDMEEMMSEQENP-DSSEPVVEDERLHH 250
S D D ++ +++E D ++ +E RL H
Sbjct: 588 SSDSEYDSDDDRTKEERAYDKAKRRIEKRRLEH 620
Score = 31.6 bits (70), Expect = 2.9
Identities = 46/232 (19%), Positives = 89/232 (38%), Gaps = 24/232 (10%)
Query: 139 EPQNIEDEAKEQIQSLLHEMVHAEHVEGEDLQQEDGPTGEPQQEDDEFLMATDVDDRFET 198
E N +D+A +I+++ + + E + +E + +++++ ET
Sbjct: 213 ESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEE-----------LET 261
Query: 199 LEPEVSHEETEHSYHVEETVSQDCNQDMEEMMSEQENPDSSEPVVEDERLHHDTDDVTYQ 258
+ + S ++ EETV D + + +E ++ +D D +
Sbjct: 262 GKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKK 321
Query: 259 VYEEQAVYEPLENEGIEITEVTAPPED----NPVEDSQVIVEEVSIFPVEEQQEVPPETN 314
E++ E + +G V A E E+ Q EE I +EE + E
Sbjct: 322 KGEKEEK-EKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEE 380
Query: 315 RKTDDPEQKAKVK--------KKKPKLLNKFDKTIKAELDAAEKLRKRGKIE 358
R + ++ K K KK+ KLL K + +A +A KL + +E
Sbjct: 381 RLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQGVE 432
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 48.9 bits (115), Expect = 2e-05
Identities = 53/265 (20%), Positives = 117/265 (44%), Gaps = 19/265 (7%)
Query: 146 EAKEQIQSLLHEMVHAEHV-EGEDLQQEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVS 204
E +E+I+ L +M E + E E+ +QE+ E ++ ++ +++ E ++
Sbjct: 374 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 433
Query: 205 HEET-----EHSYHVEETV-SQDCNQDMEEMMSEQENPDSSEPVVEDERLHHDTDDVTYQ 258
+E E H +E + ++ Q+ EEM ++E E + + H+ + + Q
Sbjct: 434 EQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQ 493
Query: 259 ---VYEEQAVYEPLENEGIEITEVTAPPEDNPVEDSQVIVEEVSIFPVEEQQEVPPETNR 315
V+ ++ E + E E E+ E + I E+ + EQ+E+ E
Sbjct: 494 EEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEE--KIREQEEMMQEQEE 551
Query: 316 KTDDPEQK----AKVKKKKPKLLNKFDKTIKAELDAAEKLRKRGKIEEAVNAFKELVRKY 371
K + E+K K+++++ K+ + +K + + E+ K + EE + +E++++
Sbjct: 552 KMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQ 611
Query: 372 PQSPRARYGKAQCEDDLAEKRRSNE 396
+ + K CE + EK + E
Sbjct: 612 EEKMWEQEEK-MCEQE--EKMQEQE 633
Score = 37.7 bits (86), Expect = 0.040
Identities = 56/270 (20%), Positives = 115/270 (42%), Gaps = 15/270 (5%)
Query: 122 EEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQSLLHEMVHAEHVEGEDLQQEDGPTGEPQQ 181
+E E E E++ EA+ E++ +EQ + + + E + +QE E +Q
Sbjct: 400 QEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQ 459
Query: 182 EDDEFLMATD-VDDRFETLEPEVSHEETEHSYHVEETV--SQDCNQDMEEMMSEQENP-- 236
E +E + + ++ E + E E EE V ++ D EE + EQE
Sbjct: 460 EQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMW 519
Query: 237 DSSEPVVEDERLHHDTDDVTYQVYEEQAVYEPLENEGIEITEVTAPPEDNPVEDSQVIVE 296
E + E E + ++ ++ E++ + + E + E E E ++ ++ +
Sbjct: 520 RQEEKIREQEEKIREQEE---KIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQ 576
Query: 297 EVSIFPVEEQQEVPPETNRKTDDPEQKAKVKKKKPKLLNKFDKTIKAELDAAEKLRKRGK 356
E I EQ+E E K EQ+ K+++++ + + +K + E E+ K +
Sbjct: 577 EEKI---REQKEKIREQEEKI--WEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE 631
Query: 357 IEEAVNAFKELVRKYPQSPRARYGKAQCED 386
EE + +E + + Q R R + + ++
Sbjct: 632 QEEKMRRQEE--KMWEQEVRLRQQEEKMQE 659
Score = 35.8 bits (81), Expect = 0.15
Identities = 49/242 (20%), Positives = 105/242 (43%), Gaps = 21/242 (8%)
Query: 131 EEQVPVEAEPQNIEDEAKE---QIQSLLHEMVHAEHV-EGEDLQQEDGPTGEPQQEDDEF 186
E+ ++ + Q +E E E ++ L ++ A+ + + LQ E G+ Q
Sbjct: 221 EKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAK 280
Query: 187 LMATDVDDRFETLEPEVSHEETEHSYHVEETVSQDCNQDMEEMMSEQENP--DSSEPVVE 244
L A ++ L ++ ++ E + EE + Q+ EE + EQE + E + E
Sbjct: 281 LQAQVEENE---LWNRLNQQQEEKMWRQEEKI-----QEWEEKIQEQEEKIREQEEKIRE 332
Query: 245 DERLHHDTDDVTYQVYEEQAVYEPL----ENEGIEITEVTAPPEDNPVEDSQVIVEEVSI 300
E +++ ++ E+ E + E + + E+ E+ E + + E+ I
Sbjct: 333 QEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKI 392
Query: 301 FPVEEQQEVPPETNRKTDDPEQKAKVKKKKPKLLNKFDKTIKAELD---AAEKLRKRGKI 357
EE+++ + + EQ+AK+ +++ K+ + +K + E EK+ ++ KI
Sbjct: 393 REQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKI 452
Query: 358 EE 359
E
Sbjct: 453 RE 454
>gi|110347568 centrosomal protein 152kDa [Homo sapiens]
Length = 1654
Score = 48.9 bits (115), Expect = 2e-05
Identities = 73/317 (23%), Positives = 139/317 (43%), Gaps = 39/317 (12%)
Query: 76 DLVDYEEVLGKLGIYDADGDGDFDVD--DAKVLLGLKERSTSEPAVPP--EEAEPHTEPE 131
D + E KLGI+ +D +G+ +++ ++ V LG+K+ + + V +E +P+ E
Sbjct: 479 DEISLYESAAKLGIHPSDSEGELNIELTESYVDLGIKKVNWKKSKVTSIVQEEDPNEELS 538
Query: 132 EQ---VPVEAEPQNI--EDEAKEQIQSLLHEMVHAEHVEGEDLQQ--EDGPTGEPQQEDD 184
+ + ++AE Q + + K + S L + H + EDL Q +D + E + + D
Sbjct: 539 KDEFILKLKAEVQRLLGSNSMKRHLVSQLQNDLKDCHKKIEDLHQVKKDEKSIEVETKTD 598
Query: 185 -----------EFLMATDVDDRFETLEPEVS-----HEETEHSYHVEETVSQDCNQDMEE 228
E + V D L+ E+ ++E + + +QD M +
Sbjct: 599 TSEKPKNQLWPESSTSDVVRDDILLLKNEIQVLQQQNQELKETEGKLRNTNQDLCNQMRQ 658
Query: 229 MMSEQENPDSSEPVVEDERL---HHDTDDVTYQVYEEQAVYEPLEN----EGIEITEVTA 281
M+ + ++ D E V ER HH+ + Q+ E LE E E T +
Sbjct: 659 MVQDFDH-DKQEAVDRCERTYQQHHEA--MKTQIRESLLAKHALEKQQLFEAYERTHLQL 715
Query: 282 PPEDNPVEDSQVIVEEVSIFPVEEQQEVPPETNRKTDDPEQKAKVKKKKPKLLNKFDKTI 341
E + + V+E + E+ + T RKT + EQ+ + +K K KL+ + +K
Sbjct: 716 RSELDKLNKEVTAVQECYLEVCREKDNLEL-TLRKTTEKEQQTQ-EKIKEKLIQQLEKEW 773
Query: 342 KAELDAAEKLRKRGKIE 358
+++LD K K+ ++
Sbjct: 774 QSKLDQTIKAMKKKTLD 790
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 48.1 bits (113), Expect = 3e-05
Identities = 51/259 (19%), Positives = 115/259 (44%), Gaps = 15/259 (5%)
Query: 146 EAKEQIQSLLHEMVHAEHV-EGEDLQQEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVS 204
E +E+I+ L +M E + E E+ +QE+ E ++ ++ +++ E ++
Sbjct: 388 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 447
Query: 205 HEET-----EHSYHVEETV-SQDCNQDMEEMMSEQENPDSSEPVV-EDERLHHDTDDVTY 257
+E E H +E + ++ Q+ EEM ++E E + + E++H + +
Sbjct: 448 EQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRK 507
Query: 258 QVYEEQAVYEPLENEGIEITEVTAPPEDNPVEDSQVIVEEVSIFPVEEQQEVPPETNRKT 317
Q + E + + +I E E+ + I E+ ++ EE+ + +
Sbjct: 508 QEEKVWRQEEKIREQEEKIRE----QEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEE 563
Query: 318 DDPEQKAKVKKKKPKLLNKFDKTIKAELDAAEKLRKRGKIEEAVNAFKELVRKYPQSPRA 377
EQ+ K+ +++ K+ + +K + E E+ KR + EE + +E +R+ + +
Sbjct: 564 KRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQE 623
Query: 378 RYGKAQCEDDLAEKRRSNE 396
+ K + ++ EK R E
Sbjct: 624 QEEKIREQE---EKIREQE 639
Score = 47.8 bits (112), Expect = 4e-05
Identities = 62/294 (21%), Positives = 134/294 (45%), Gaps = 15/294 (5%)
Query: 122 EEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQSLLHEMVHAEHVEGEDLQQEDGPTGEPQQ 181
+E E E E++ EA+ E++ +EQ + + + E + +QE E +Q
Sbjct: 414 QEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQ 473
Query: 182 EDDEFLMATDVDDRFETL--EPEVSHEETEHSYHVEETV--SQDCNQDMEEMMSEQENP- 236
E +E + E + + E HE+ E EE V ++ ++ EE + EQE
Sbjct: 474 EQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKM 533
Query: 237 -DSSEPVVEDERLHHDTDDVTYQVYEEQAVYEPLENEGIEITEVTAPPEDNPVEDSQVIV 295
E + E E + + + +++E++ ++E + + E ++ E ++ +V
Sbjct: 534 WRQEEKIREQEEMWREEE----KMHEQEKIWEEEKRQEQE-DKMWRQEEKIREQEEKVWR 588
Query: 296 EEVSIFPVEEQQEVPPETNRKTDDP--EQKAKVKKKKPKLLNKFDKTIKAELDAAEKLRK 353
+E I EE+++ E K ++ EQ+ K+++++ K+ + +K + E E+ K
Sbjct: 589 QEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEK 648
Query: 354 RGKIEEAVNAFKELVRKYPQSPRARYGKAQCEDDLAEKRRSNEVLRGAIETYQE 407
G+ EE + +E +++ ++ + K + ++ + R E +R E QE
Sbjct: 649 MGEQEEKMCEQEEKMQEQEETMWRQEEKIREQE--KKIREQEEKIREQEEMMQE 700
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 47.4 bits (111), Expect = 5e-05
Identities = 63/294 (21%), Positives = 110/294 (37%), Gaps = 27/294 (9%)
Query: 111 ERSTSEPAVPPEEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQSLLHEMVHAEHVEGEDLQ 170
E+S E + E+ E T+ E+V E E + E+E KE+ E E EG + +
Sbjct: 448 EKSEKETVIVEEQTE-ETQVTEEVTEEEEKEAKEEEGKEE------EGGEEEEAEGGEEE 500
Query: 171 QEDGPTGEPQQEDDEFL--MATDVDDRFETLEPEV----SHEETEHSYHVEETVSQDCNQ 224
+ P E + E + + E PE S E + + ++
Sbjct: 501 TKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKS 560
Query: 225 DMEEMMSEQENPDSSEPVVEDERLHHDTDDVTYQVYEEQA---VYEPLENEGIEITEVTA 281
E E+E S V E+ + E ++ P++ E E +
Sbjct: 561 PPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKS 620
Query: 282 PPEDNPVEDSQVIVEEVSIFPVEEQQEVPPETNRKTDDPEQKAKVKKKKPKLLNKFDKTI 341
P ++ ++V E + P +E+ + PE + + E K+ K K P +
Sbjct: 621 PVKEEAKSPAEVKSPEKAKSPTKEEAK-SPEKAKSPEKEEAKSPEKAKSP---------V 670
Query: 342 KAELDAAEKLRKRGKIE-EAVNAFKELVRKYPQSPRARYGKAQCEDDLAEKRRS 394
KAE + EK + K E ++ K V++ +SP + E EK +S
Sbjct: 671 KAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKS 724
Score = 40.8 bits (94), Expect = 0.005
Identities = 58/268 (21%), Positives = 109/268 (40%), Gaps = 25/268 (9%)
Query: 110 KERSTSEPAVPPEEAEPHT--EPEEQVPVEAEPQNIEDEAKEQIQSLLHEMVHAEHVEGE 167
+E + E A PE+A+ PE + P + E ++ D+ E+ +S + E V +
Sbjct: 742 EEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKS 801
Query: 168 DLQQEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEETEHSYHVEETVSQDCNQDME 227
L+++ + + +E +++ + ++ + ++ E +++ +
Sbjct: 802 PLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKK 861
Query: 228 EMMSEQENP-----DSSEPVVEDERLHHDTDDVTYQVYEEQAVYEPLENEG---IEITEV 279
E ++E P + EP VE + + + E++ E E +E+ E
Sbjct: 862 EEAPKKEAPKPKVEEKKEPAVEKPK--ESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKED 919
Query: 280 TAPPEDNPV---EDSQVIVEEVSIFPVEEQQEVPPETNRKTDDPEQKAKVKKKKPKLLNK 336
P E V E +E S E++E PE K D E+KAK ++KPK K
Sbjct: 920 AKPKEKTEVAKKEPDDAKAKEPS--KPAEKKEAAPE---KKDTKEEKAKKPEEKPKTEAK 974
Query: 337 F---DKTIKAE--LDAAEKLRKRGKIEE 359
DKT+ E AEK K ++
Sbjct: 975 AKEDDKTLSKEPSKPKAEKAEKSSSTDQ 1002
Score = 36.2 bits (82), Expect = 0.12
Identities = 64/278 (23%), Positives = 110/278 (39%), Gaps = 28/278 (10%)
Query: 110 KERSTSEPAVPPEEAEPHTEPEEQVPVEAE-PQNIEDEAKEQIQSLLHEMVHAEHVEGED 168
K + E PPE P E E + P E + P+ + AKE+ +S E E +
Sbjct: 551 KSPAKEEAKSPPEAKSPEKE-EAKSPAEVKSPEKAKSPAKEEAKSPA-EAKSPEKAKSPV 608
Query: 169 LQQEDGPTGEPQQEDDEFLMATDVDDRFETLEP---EVSHEETEHSYHVEETVSQDCNQD 225
++ P +E +V + P E E S EE S + +
Sbjct: 609 KEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPE--KA 666
Query: 226 MEEMMSEQENPDSSEPVVEDERLHHDTDDVTYQVYEEQAVYEPLENEGIEITEVTAPPE- 284
+ +E ++P+ ++ V+ E + V EE E ++ + E PE
Sbjct: 667 KSPVKAEAKSPEKAKSPVKAEA--KSPEKAKSPVKEEAKSPEKAKS---PVKEEAKSPEK 721
Query: 285 -DNPVEDSQVIVEEVSIFPVEEQQEVP-----PETNRKTD--DPEQKAKVKKKKPKLLNK 336
+PV++ E+ PV+E+ + P PE + D PE K K++ +K
Sbjct: 722 AKSPVKEEAKTPEKAK-SPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADK 780
Query: 337 FDK----TIKAELDAAEKLRKRGKIEEAVNAFKELVRK 370
F + +K E+ + EK + K E+A KE+ +K
Sbjct: 781 FPEKAKSPVKEEVKSPEKAKSPLK-EDAKAPEKEIPKK 817
>gi|104526627 triadin [Homo sapiens]
Length = 729
Score = 46.6 bits (109), Expect = 9e-05
Identities = 81/415 (19%), Positives = 164/415 (39%), Gaps = 85/415 (20%)
Query: 57 WFMVIALLGVWTSVAVVWFDLVDYEEV----LGKLG-----------------IY----- 90
W +VIAL+ W++VA+V FDLVDY+ + K+G IY
Sbjct: 50 WLLVIALIITWSAVAIVMFDLVDYKNFSASSIAKIGSDPLKLVRDAMEETTDWIYGFFSL 109
Query: 91 ---------DADGDGDFDVDDAKVLLGLKERSTSEPAVPPEEAEPHTEPEEQVPVEAEPQ 141
+ D DGD D D ++ E + + ++ E +PE ++ + +
Sbjct: 110 LSDIISSEDEEDDDGDEDTDKGEI----DEPPLRKKEIHKDKTEKQEKPERKIQTKVTHK 165
Query: 142 NIEDEAKEQIQSLLHEMVHAEHVEGEDLQQEDGPTGEPQQEDDEFLMATDVDDRFETLEP 201
+++ KE+++ E + E +++++ P E + E A + E +
Sbjct: 166 E-KEKGKEKVRE--KEKPEKKATHKEKIEKKEKP--ETKTLAKEQKKAKTAEKSEEKTKK 220
Query: 202 EVSHEETEHSYHVEETVSQDCNQDMEEMMSEQENPDSSEPVVEDERLHHDTDDVTYQVY- 260
EV + E V++T ++ +++++ S+ + + E + H D + Y
Sbjct: 221 EVKGGKQE---KVKQTAAK--VKEVQKTPSKPKEKEDKEKAAVSK--HEQKDQYAFCRYM 273
Query: 261 ------------EEQAVYEPLENEGIEITEVTAPPEDNP-VEDSQVIVEEVSIFPVEEQQ 307
+ A+ PL E + + P +P +E+ + ++ E +
Sbjct: 274 IDIFVHGDLKPGQSPAIPPPLPTE-----QASRPTPASPALEEKEGEKKKAEKKVTSETK 328
Query: 308 EVPPETNRKTDDPEQKAKVKKKKP-KLLNKFDKTIKAELDAA----------EKLRKRGK 356
+ E +K + E V+KK+P K T+K AA +K +K +
Sbjct: 329 KKEKEDIKKKSEKETAIDVEKKEPGKASETKQGTVKIAAQAAAKKDEKKEDSKKTKKPAE 388
Query: 357 IEEAVNAFKELVRKY---PQSPRARYGKAQCEDDLAEKRRSNEVLRGAIETYQEV 408
+E+ +E K+ +SP+ + + A+ R+ E + GA+ + V
Sbjct: 389 VEQPKGKKQEKKEKHVEPAKSPKKEHSVPSDKQVKAKTERAKEEI-GAVSIKKAV 442
Score = 32.7 bits (73), Expect = 1.3
Identities = 38/160 (23%), Positives = 65/160 (40%), Gaps = 15/160 (9%)
Query: 102 DAKVLLGLKERSTSEPAVPPEEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQSLLHEMVHA 161
+AK + K + + V PE+ H +PEE+V + + IE AK + A
Sbjct: 529 EAKPAISEKVQIHKQDIVKPEKTVSHGKPEEKVLKQVKAVTIEKTAKPK------PTKKA 582
Query: 162 EHVEGEDLQ-QEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEETEHSYHVEETVSQ 220
EH E E + D P P+ + T+ + + + S E+ + + EE VS
Sbjct: 583 EHREREPPSIKTDKPKPTPKGTSE----VTESGKKKTEISEKESKEKADMKHLREEKVST 638
Query: 221 DCNQDMEEMMSEQENPDSSEPVVED----ERLHHDTDDVT 256
+++ E P VED ++ T+DV+
Sbjct: 639 RKESLQLHNVTKAEKPARVSKDVEDVPASKKAKEGTEDVS 678
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 46.2 bits (108), Expect = 1e-04
Identities = 69/318 (21%), Positives = 123/318 (38%), Gaps = 37/318 (11%)
Query: 81 EEVLGKLGIYDADGDGDFDVDDAKVLLGLKERSTSEPAVPPEEAEPHTEPEEQVPVEAEP 140
EE++ + + D + + + L + + + A +E EP E EE ++
Sbjct: 454 EEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPV 513
Query: 141 QNIEDEAKEQIQSLLHEMVHAEHVEGEDLQQEDGPTGEPQQEDDEFLMATDVDDRFETLE 200
+ E KE+ EGE ++E+G E ++E+DE + ++ E
Sbjct: 514 KATAPEVKEE--------------EGEK-EEEEGQ--EEEEEEDEGAKSDQAEEGGSEKE 556
Query: 201 PEVSHEETEHSYHVEETVSQDCNQDMEEMMSEQENPDSSEPVVEDERLHHDTDDVTYQVY 260
EE E E + + E E++ + SE V E L D +
Sbjct: 557 GSSEKEEGEQE---EGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKA 613
Query: 261 EEQAVYEPLENEGIEITEVTAPPEDNPVEDSQVIVEEVSIFPVEEQQEVP---PETNRKT 317
+ P+E +G +P +PVE+ V PVEE+ + P K
Sbjct: 614 KSPVPKSPVEEKG------KSPVPKSPVEEKG--KSPVPKSPVEEKGKSPVPKSPVEEKG 665
Query: 318 DDPEQKAKVKKKKPKLLNKF---DKTIKAELDAAEKLRKRGK-IEEAVNAFKELVRKYPQ 373
P K+ V++K + K + KAE+ E+ + K ++EA +E V K +
Sbjct: 666 KSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPK--EEKVEKKEE 723
Query: 374 SPRARYGKAQCEDDLAEK 391
P+ K + E + E+
Sbjct: 724 KPKDVPEKKKAESPVKEE 741
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 46.2 bits (108), Expect = 1e-04
Identities = 69/318 (21%), Positives = 123/318 (38%), Gaps = 37/318 (11%)
Query: 81 EEVLGKLGIYDADGDGDFDVDDAKVLLGLKERSTSEPAVPPEEAEPHTEPEEQVPVEAEP 140
EE++ + + D + + + L + + + A +E EP E EE ++
Sbjct: 78 EEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPV 137
Query: 141 QNIEDEAKEQIQSLLHEMVHAEHVEGEDLQQEDGPTGEPQQEDDEFLMATDVDDRFETLE 200
+ E KE+ EGE ++E+G E ++E+DE + ++ E
Sbjct: 138 KATAPEVKEE--------------EGEK-EEEEGQ--EEEEEEDEGAKSDQAEEGGSEKE 180
Query: 201 PEVSHEETEHSYHVEETVSQDCNQDMEEMMSEQENPDSSEPVVEDERLHHDTDDVTYQVY 260
EE E E + + E E++ + SE V E L D +
Sbjct: 181 GSSEKEEGEQE---EGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKA 237
Query: 261 EEQAVYEPLENEGIEITEVTAPPEDNPVEDSQVIVEEVSIFPVEEQQEVP---PETNRKT 317
+ P+E +G +P +PVE+ V PVEE+ + P K
Sbjct: 238 KSPVPKSPVEEKG------KSPVPKSPVEEKG--KSPVPKSPVEEKGKSPVPKSPVEEKG 289
Query: 318 DDPEQKAKVKKKKPKLLNKF---DKTIKAELDAAEKLRKRGK-IEEAVNAFKELVRKYPQ 373
P K+ V++K + K + KAE+ E+ + K ++EA +E V K +
Sbjct: 290 KSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPK--EEKVEKKEE 347
Query: 374 SPRARYGKAQCEDDLAEK 391
P+ K + E + E+
Sbjct: 348 KPKDVPEKKKAESPVKEE 365
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 45.8 bits (107), Expect = 1e-04
Identities = 64/283 (22%), Positives = 112/283 (39%), Gaps = 32/283 (11%)
Query: 81 EEVLGKLGIYDADGDGDFDVDDAKVLLGLKERSTSEPAVPPEEAEPHTEPEEQVPVEAEP 140
EE G+ + +G G+ + ++ G E E EE E E EE+ E E
Sbjct: 843 EEEEGEGEEEEGEGKGEEEGEE-----GEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEE 897
Query: 141 QNIEDEAKEQIQSLLHEMVHAEHVEGEDLQQEDGPTGEPQQEDDEFLMATDVDDRFETLE 200
+ E E +E+ + E EGE +E+G GE + E++E E +
Sbjct: 898 EEGEGEGEEEGEG------EGEEEEGEGKGEEEGEEGEGEGEEEE--------GEGEGED 943
Query: 201 PEVSHEETEHSYHVEETVSQDCNQDMEEMMSEQENPDSSEPVVEDERLHHDTDDVTYQVY 260
E EE E + EE + ++ E E+ + E E E + ++ +
Sbjct: 944 GEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEE-- 1001
Query: 261 EEQAVYEPLENEGIEITEVTAPPEDNPVEDSQVIVEEVSIFPVEEQQEVPPETNRKTDDP 320
E EG E E E+ + +V EE EE+ E E K +
Sbjct: 1002 ---------EGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEG 1052
Query: 321 EQKAKVKKKKPKLLNKFDKTIKAELDA--AEKLRKRGKIEEAV 361
E+ + ++++ + K+ +T + E + E+ +K KI+ +V
Sbjct: 1053 EENRRNREEEEEEEGKYQETGEEENERQDGEEYKKVSKIKGSV 1095
Score = 36.2 bits (82), Expect = 0.12
Identities = 50/196 (25%), Positives = 80/196 (40%), Gaps = 14/196 (7%)
Query: 81 EEVLGKLGIYDADGD-GDFDVDDAKVLLGLKERSTSEPAVPPEEAEPHTEPEEQVPVEAE 139
EE GK + +GD G+ + ++ + KE EE + E EE+ E E
Sbjct: 778 EERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEE---EGE 834
Query: 140 PQNIEDEAKEQIQSLLHEMVHAEHVEGEDLQQEDGPTGEPQQEDDEFLMATDVD--DRFE 197
+ E E +E E E EGE +E+G GE ++E +E + + +
Sbjct: 835 GEEEEGEGEE-------EEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEG 887
Query: 198 TLEPEVSHEETEHSYHVEETVSQDCNQDMEEMMSEQENPDSSEPVVEDERLHHDTDDVTY 257
E E EE E EE + ++ E E+E + E E+E + +D
Sbjct: 888 EEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEG-EEGEGEGEEEEGEGEGEDGEG 946
Query: 258 QVYEEQAVYEPLENEG 273
+ EE+ +E E EG
Sbjct: 947 EGEEEEGEWEGEEEEG 962
Score = 34.7 bits (78), Expect = 0.34
Identities = 56/281 (19%), Positives = 112/281 (39%), Gaps = 34/281 (12%)
Query: 149 EQIQSLLHEMVHAEHVEGEDLQQEDGPTGEPQQEDDEFLMATDVDDRFETLEP--EVSHE 206
E+ LL EM ++ + G T + +M+ + +++ L P + +
Sbjct: 469 EEPDYLLDEMTKEAEIDNSSTVESLGETTDILNMTH--IMSLNSNEKSLKLSPVQKQKKQ 526
Query: 207 ETEHSYHVEETVSQDCNQDMEEMMSEQENPDSSEPVVEDERLHHDTDDVTYQVYEEQAVY 266
+T + ++++ + D E MSE + + + V + + T + + ++ V
Sbjct: 527 QTIGELTQDTALTENDDSDEYEEMSEMKEGKACKQHVS-QGIFMTQPATTIEAFSDEEVE 585
Query: 267 EPLENEGIEITEVTAPPEDNPVEDSQVIVEEVSIFPVEEQQEVPPETNRKTDDPEQKAKV 326
P E EG E ++ N +E+ +V E ++ ++E +T +DD KA+V
Sbjct: 586 IPEEKEGAEDSK------GNGIEEQEVEANEENVKVHGGRKE---KTEILSDDLTDKAEV 636
Query: 327 KKKKPKLLNKFDKTIKA-------------------ELDAAEKLRKRGKIEEAVNAFKEL 367
+ K K + + + + E + EK + RG++E KEL
Sbjct: 637 SEGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKEL 696
Query: 368 VRKYPQSPRARYGKAQCEDDLA-EKRRSNEVLRGAIETYQE 407
K R + Q E + +K R+ E+ G E + E
Sbjct: 697 AEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGE 737
Score = 32.3 bits (72), Expect = 1.7
Identities = 42/179 (23%), Positives = 67/179 (37%), Gaps = 15/179 (8%)
Query: 108 GLKERSTSEPAVPPEEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQSLLHEMVHA---EHV 164
G K++ E P E + E EE + E Q ++ + + EM EH
Sbjct: 677 GEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHG 736
Query: 165 EGE----DLQQEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEETEHSYHVEETVSQ 220
EGE D ++E+ GE ++E + +V+ E E E EE E
Sbjct: 737 EGEEEEGDREEEEEKEGEGKEEGE----GEEVEGEREKEEGERKKEERAGKEEKGEEEGD 792
Query: 221 DCNQDMEEMMSEQENPDSSEPV----VEDERLHHDTDDVTYQVYEEQAVYEPLENEGIE 275
+ EE E + V VE+ + + ++ + EE+ E E EG E
Sbjct: 793 QGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEE 851
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 45.8 bits (107), Expect = 1e-04
Identities = 75/346 (21%), Positives = 138/346 (39%), Gaps = 53/346 (15%)
Query: 99 DVDDAKVLLGLKERSTSEPAVPPEEAEPHTEPEEQVPVEAEPQNIEDEAKE-----QIQ- 152
D D+ + + R+ E +E E + +QV V A+ ++EAK Q++
Sbjct: 31 DDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEG 90
Query: 153 ----SLLHEMVHAEHVEGEDLQQEDGPTGEPQQEDDEFL-----------MATDVDDRFE 197
+ L + E + LQ+ E Q+E D + M D + E
Sbjct: 91 DDEAAFLERLARREERRQKRLQE----ALERQKEFDPTITDASLSLPSRRMQNDTAEN-E 145
Query: 198 TLEPEVSHEETEHSYHVEET--------------VSQDCNQDMEEMMSEQENPDSSEPVV 243
T E E E + Y +EET ++ +D E+ E+E P +
Sbjct: 146 TTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGS--I 203
Query: 244 EDERLHHDTDDVTYQVYEEQAVYEPLENEGIEITEVTAPPEDNPVEDSQVIVEEVSIF-P 302
+ ++ ++ T + EE V L+N I E P ++ E +E+S
Sbjct: 204 GENQVEVMVEEKTTESQEETVVMS-LKNGQISSEE---PKQEEEREQGS---DEISHHEK 256
Query: 303 VEEQQEVPPETNRKTDDPEQKAKVKKKKPKLLNKFDKTIKAELDAAEKLRKRGKIEEAVN 362
+EE+ + E R + E++ ++K ++ K + I+AE AA + R+R + EE
Sbjct: 257 MEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERER 316
Query: 363 AFKELVRKYPQSPRARYGKAQCEDDLAEKRRSNEVLRGAIETYQEV 408
+E R + R + + + + E++R E + A E Q +
Sbjct: 317 MREEEKRAAEERQRIKEEEKRAAE---ERQRIKEEEKRAAEERQRI 359
Score = 44.3 bits (103), Expect = 4e-04
Identities = 60/312 (19%), Positives = 130/312 (41%), Gaps = 33/312 (10%)
Query: 131 EEQVPVEAEPQNIEDEAKEQIQSLLHEMVHAEHVEGEDLQQEDGPTGEPQQEDDEFLMAT 190
E QV V E + E + + + SL + + +E EP+QE++ +
Sbjct: 205 ENQVEVMVEEKTTESQEETVVMSLKNGQISSE---------------EPKQEEEREQGSD 249
Query: 191 DVDDRFETLEPEVSHEETEHS-YHVEETVSQDCNQDMEEMMSEQENPDSSEPVVEDERLH 249
++ + E + E E + EE QD +++ E+ ++ E ER
Sbjct: 250 EISHHEKMEEEDKERAEAERARLEAEERERIKAEQD-KKIADERARIEAEEKAAAQERER 308
Query: 250 HDTDDVTYQVYEEQAVYEPLENEGIEITEVTAPPEDNPVEDSQVIVEEVSIFPVEEQQEV 309
+ ++ EE+ E E + I+ E A E +++ + E EE++
Sbjct: 309 REAEERERMREEEKRAAE--ERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRA 366
Query: 310 PPETNRKTDDPEQKAKVKKKKPKLLNKFDKTIKAELDAAEKLRKRG-KIEEAVNAFKELV 368
E R + E+KAKV+++K +K ++ + A ++ + +G K+E+ + K +
Sbjct: 367 AEERQRARAEEEEKAKVEEQKR------NKQLEEKKHAMQETKIKGEKVEQKIEG-KWVN 419
Query: 369 RKYPQSPRARYG--KAQCEDDLAEKRRSNEVLRGAIETYQEVASLPDVPADLLKLSLKRR 426
K Q + + K Q E+ + + E L+ T+++ ++ + +K + +
Sbjct: 420 EKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKK----EEIKDEKIKKDKEPK 475
Query: 427 SDRQQFLGHMRG 438
+ + F+ +G
Sbjct: 476 EEVKSFMDRKKG 487
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 44.7 bits (104), Expect = 3e-04
Identities = 33/158 (20%), Positives = 76/158 (48%), Gaps = 9/158 (5%)
Query: 93 DGDGDFDVDDAKVLLGLKERSTSEPAVPPEEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQ 152
D + + +++ +V+ LK R +EA+ +P+E+ + + E+ E+++
Sbjct: 2177 DDEEEGGIEEEEVIPFLKRRWRKR-----KEAKRGDKPKEKFSSQVDEVESEEHFSEEME 2231
Query: 153 SLLHEMVHAEHVEGEDLQQ----EDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEET 208
SLL E+ E + E+ ++ E+ E ++E++E + +++ E E ++
Sbjct: 2232 SLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKK 2291
Query: 209 EHSYHVEETVSQDCNQDMEEMMSEQENPDSSEPVVEDE 246
+ E ++ ++ EE+MSE+E S+ E+E
Sbjct: 2292 KEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEE 2329
Score = 41.6 bits (96), Expect = 0.003
Identities = 48/229 (20%), Positives = 98/229 (42%), Gaps = 12/229 (5%)
Query: 109 LKERSTSEPAVPPEEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQSLLHEMVHAEHVEGED 168
++ E + EE++ + E + + E IE+E E I L + + D
Sbjct: 2150 MRRMINKEEKMTEEESKLARKHSEVILDDEEEGGIEEE--EVIPFLKRRWRKRKEAKRGD 2207
Query: 169 LQQEDGPTGEPQQEDDEFLMATDVDDRFETLEPE--VSHEETEHSYHVEETVSQDCNQDM 226
+E + + E +E + +++ + LE + +S EE E EE ++ ++
Sbjct: 2208 KPKEKFSSQVDEVESEEHF-SEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEE 2266
Query: 227 EEMMSEQENPDSSEPVVEDERLHHDTDDVTYQVYEEQAVYEPLENEGIEITEVTAPPEDN 286
EE E+E + E+E+ + +V E++ V+E E E I E T D
Sbjct: 2267 EERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFE--EKEEIMSEEETESLSDE 2324
Query: 287 PVEDSQVIVEEVSIFPVEEQQEVPPETNRKTDDPEQKAKVKKKKPKLLN 335
E+ +EE V+ ++E+ + ++ EQ+ K + + ++L+
Sbjct: 2325 EEEEESCSLEE----EVDREKEI-LKKEKQFKLQEQRRKSLRGRERVLS 2368
Score = 33.1 bits (74), Expect = 0.98
Identities = 38/182 (20%), Positives = 72/182 (39%), Gaps = 20/182 (10%)
Query: 193 DDRFETLEPEVSHEETEHSYHVEETVSQDCNQDMEEMMSEQENPDSSEPVVEDERLHHDT 252
D+ TLE EVS E E V E + + + + E+ +L +
Sbjct: 1540 DEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEE 1599
Query: 253 DDVTYQVYEEQAVYEPLENEGIEITEVTAPPEDNPVEDSQVIVEEVSIFPVEEQQEVPPE 312
+ + + + L ++IT+ +D ++ E +++E +
Sbjct: 1600 EKLAQEERQLAQEERKLAQAYVKITQ----------DDREMAQAEGKF---AQKEETLAQ 1646
Query: 313 TNRKTDDPEQKAKVKKKKPKLLNKFDKTIKAELDAAEKLRKR-GKIEEAVNAFKELVRKY 371
K ++ K+ +K+ KL K++K + E EKL K+ GK+ E N + V +
Sbjct: 1647 RGEKLS--QEAEKLAQKRKKLAKKWEKVAREE----EKLAKKGGKLAEVKNILAQKVEEL 1700
Query: 372 PQ 373
PQ
Sbjct: 1701 PQ 1702
Score = 33.1 bits (74), Expect = 0.98
Identities = 39/135 (28%), Positives = 59/135 (43%), Gaps = 21/135 (15%)
Query: 101 DDAKVLLGLKERSTSEPAVPPEEAEPHTE-PEEQVPVEAEPQNIEDEAKEQIQSLLHEMV 159
++ + LL E+ S + EE E E EE+V E E + E+E +E+
Sbjct: 2228 EEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEK--------- 2278
Query: 160 HAEHVEGEDLQQEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEETEHSYHVEETVS 219
E E E +++ E QE +E FE E +S EETE S EE
Sbjct: 2279 QVEKEEEEKKKKKKEKKKEEVQEKEEV---------FEEKEEIMSEEETE-SLSDEEEEE 2328
Query: 220 QDCNQDMEEMMSEQE 234
+ C+ + EE+ E+E
Sbjct: 2329 ESCSLE-EEVDREKE 2342
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 44.7 bits (104), Expect = 3e-04
Identities = 51/195 (26%), Positives = 78/195 (40%), Gaps = 19/195 (9%)
Query: 135 PVEAEPQNIEDEAK---EQIQSLLHEMVHAEHVEGEDLQQEDGPTGEPQQEDDEFLMATD 191
P+E + EDE + E+ +S E E E ED +D + + DDE T
Sbjct: 1026 PLELDSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDE---DTA 1082
Query: 192 VDDRFETLEPEVSHEETEH--SYHVEETVSQDCNQDMEEMMSEQENPDSSEP----VVED 245
+ + E E + EET + E T S + ++ E S + +P SSE V +
Sbjct: 1083 LSEASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVARE 1142
Query: 246 ERLHHDTDDVTYQVYEEQAVYEPLENEGIEITEVTAPPEDNPVEDSQVIVEEVSIFPVEE 305
E + +++ + A E E +G E A P DS + EEV I E
Sbjct: 1143 EEEEEEEEEMVAEESMASAGPEDFEQDG----EEAALAPGAPAVDSLGMEEEVDI---ET 1195
Query: 306 QQEVPPETNRKTDDP 320
+ P E D+P
Sbjct: 1196 EAVAPEERPSMLDEP 1210
Score = 35.8 bits (81), Expect = 0.15
Identities = 58/258 (22%), Positives = 93/258 (36%), Gaps = 49/258 (18%)
Query: 110 KERSTSEPAVPPEEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQSLLHEMVHAEHVEGEDL 169
KE + E EE E E EE+ + + + ++ + + L E +E EG+
Sbjct: 1038 KESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEA--SEKDEGDSD 1095
Query: 170 QQE---------DGPTGEPQQEDDEFLMATDV-----DDRFETLEPEVSHEETEHSYHVE 215
++E + + E EF +++ +D E + E EE E E
Sbjct: 1096 EEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEEMVAE 1155
Query: 216 ETVS----QDCNQDMEE------------MMSEQENPDSSEPVVEDERLHH-DTDDVTYQ 258
E+++ +D QD EE + E+E +E V +ER D +
Sbjct: 1156 ESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSMLDEPPLPVG 1215
Query: 259 VYEEQAVYEPLENEGIE------------ITEVTA----PPEDNPVEDSQVIVEEVSIFP 302
V E EP E G+ EV A PE P D +V E + P
Sbjct: 1216 VEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLP 1275
Query: 303 VEEQQEVPPETNRKTDDP 320
+ Q +PP + P
Sbjct: 1276 LPLQPPLPPPRPPRPPSP 1293
>gi|83415184 transmembrane and tetratricopeptide repeat containing 1
[Homo sapiens]
Length = 774
Score = 44.3 bits (103), Expect = 4e-04
Identities = 35/119 (29%), Positives = 54/119 (45%), Gaps = 5/119 (4%)
Query: 434 GHMRGSLLTLQRLVQLFPNDTSLKNDLGVGYLLIGDNDNAKKVYEEVLSVTPNDGFAKVH 493
G + ++ + ++L+P S N+LG L D AK Y+ L + P A +
Sbjct: 389 GRNKEAIYHYRTALKLYPRHASALNNLGT---LTRDTAEAKMYYQRALQLHPQHNRALFN 445
Query: 494 YGFILKAQNKIAESIPYLKEGIESGDPGTDDGRFYFHLGDAMQRVGNKEAYKWYELGHK 552
G +LK+Q K E+I LK+ I+ G D L +R KEA + Y+ G K
Sbjct: 446 LGNLLKSQEKKEEAITLLKDSIKYGPEFADAYSSLASLLAEQERF--KEAEEIYQTGIK 502
>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
Length = 770
Score = 43.5 bits (101), Expect = 7e-04
Identities = 35/149 (23%), Positives = 61/149 (40%), Gaps = 30/149 (20%)
Query: 162 EHVEGEDLQQEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEETEHSYHVEETVSQD 221
E E E+ ++E+G T E +E++E E EE E + EE Q
Sbjct: 280 EEEEEEEEEEEEGSTSEESEEEEE----------------EEEEEEEETGSNSEEASEQS 323
Query: 222 CNQDMEEMMSEQENPDSSEPVVEDERLHHDTDDVTYQVYEEQAVYEPLENEGIEITEVTA 281
+ EE MSE E ++ ++ D D + EE E+ E T
Sbjct: 324 AEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEE------------EVGEGT- 370
Query: 282 PPEDNPVEDSQVIVEEVSIFPVEEQQEVP 310
P+ + + + + + ++ P+E +QE+P
Sbjct: 371 -PQSSALTEGDYVPDSPALLPIELKQELP 398
Score = 33.5 bits (75), Expect = 0.75
Identities = 24/110 (21%), Positives = 48/110 (43%), Gaps = 1/110 (0%)
Query: 99 DVDDAKVLLGLKERSTSEPAV-PPEEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQSLLHE 157
D+ D++ E S++E EE E E EE+ E + E+E +E+ +
Sbjct: 256 DISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSN 315
Query: 158 MVHAEHVEGEDLQQEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEE 207
A E++ +E+ E ++ ++ L+ + ++ E E + EE
Sbjct: 316 SEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEE 365
>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
Length = 780
Score = 43.5 bits (101), Expect = 7e-04
Identities = 35/149 (23%), Positives = 61/149 (40%), Gaps = 30/149 (20%)
Query: 162 EHVEGEDLQQEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEETEHSYHVEETVSQD 221
E E E+ ++E+G T E +E++E E EE E + EE Q
Sbjct: 290 EEEEEEEEEEEEGSTSEESEEEEE----------------EEEEEEEETGSNSEEASEQS 333
Query: 222 CNQDMEEMMSEQENPDSSEPVVEDERLHHDTDDVTYQVYEEQAVYEPLENEGIEITEVTA 281
+ EE MSE E ++ ++ D D + EE E+ E T
Sbjct: 334 AEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEE------------EVGEGT- 380
Query: 282 PPEDNPVEDSQVIVEEVSIFPVEEQQEVP 310
P+ + + + + + ++ P+E +QE+P
Sbjct: 381 -PQSSALTEGDYVPDSPALLPIELKQELP 408
Score = 33.5 bits (75), Expect = 0.75
Identities = 24/110 (21%), Positives = 48/110 (43%), Gaps = 1/110 (0%)
Query: 99 DVDDAKVLLGLKERSTSEPAV-PPEEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQSLLHE 157
D+ D++ E S++E EE E E EE+ E + E+E +E+ +
Sbjct: 266 DISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSN 325
Query: 158 MVHAEHVEGEDLQQEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEE 207
A E++ +E+ E ++ ++ L+ + ++ E E + EE
Sbjct: 326 SEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEE 375
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.132 0.391
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,355,361
Number of Sequences: 37866
Number of extensions: 1631993
Number of successful extensions: 10748
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 114
Number of HSP's successfully gapped in prelim test: 405
Number of HSP's that attempted gapping in prelim test: 8232
Number of HSP's gapped (non-prelim): 2217
length of query: 758
length of database: 18,247,518
effective HSP length: 110
effective length of query: 648
effective length of database: 14,082,258
effective search space: 9125303184
effective search space used: 9125303184
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.