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Search of human proteins with 14589864
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|14589864 aspartate beta-hydroxylase isoform b [Homo sapiens]
(299 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|14589864 aspartate beta-hydroxylase isoform b [Homo sapiens] 611 e-175
gi|14589860 aspartate beta-hydroxylase isoform c [Homo sapiens] 564 e-161
gi|14589866 aspartate beta-hydroxylase isoform a [Homo sapiens] 562 e-160
gi|9910364 aspartate beta-hydroxylase isoform e [Homo sapiens] 203 2e-52
gi|14589862 aspartate beta-hydroxylase isoform d [Homo sapiens] 164 7e-41
gi|150378543 MYST histone acetyltransferase (monocytic leukemia)... 52 5e-07
gi|150378463 MYST histone acetyltransferase (monocytic leukemia)... 52 5e-07
gi|150378493 MYST histone acetyltransferase (monocytic leukemia)... 52 5e-07
gi|17975763 myelin transcription factor 1 [Homo sapiens] 49 5e-06
gi|104526627 triadin [Homo sapiens] 47 2e-05
gi|221219020 NYD-SP11 protein [Homo sapiens] 45 1e-04
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 45 1e-04
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 44 2e-04
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 44 2e-04
gi|110349719 titin isoform N2-A [Homo sapiens] 43 4e-04
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 43 4e-04
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 43 4e-04
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 43 4e-04
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 43 4e-04
gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isof... 43 4e-04
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 43 4e-04
gi|194018497 FYVE, RhoGEF and PH domain containing 5 [Homo sapiens] 43 4e-04
gi|210032580 SET domain containing 1B [Homo sapiens] 42 5e-04
gi|55956788 nucleolin [Homo sapiens] 42 7e-04
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 42 7e-04
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)... 42 7e-04
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 42 7e-04
gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens] 41 0.001
gi|7657138 golgi integral membrane protein 4 [Homo sapiens] 40 0.002
gi|122937247 unc-13 homolog A [Homo sapiens] 40 0.002
>gi|14589864 aspartate beta-hydroxylase isoform b [Homo sapiens]
Length = 299
Score = 611 bits (1576), Expect = e-175
Identities = 299/299 (100%), Positives = 299/299 (100%)
Query: 1 MAEDKETKHGGHKNGRKGGLSGTSFFTWFMVIALLGVWTSVAVVWFDLVDYEEVLAKAKD 60
MAEDKETKHGGHKNGRKGGLSGTSFFTWFMVIALLGVWTSVAVVWFDLVDYEEVLAKAKD
Sbjct: 1 MAEDKETKHGGHKNGRKGGLSGTSFFTWFMVIALLGVWTSVAVVWFDLVDYEEVLAKAKD 60
Query: 61 FRYNLSEVLQGKLGIYDADGDGDFDVDDAKVLLGLKERSTSEPAVPPEEAEPHTEPEEQV 120
FRYNLSEVLQGKLGIYDADGDGDFDVDDAKVLLGLKERSTSEPAVPPEEAEPHTEPEEQV
Sbjct: 61 FRYNLSEVLQGKLGIYDADGDGDFDVDDAKVLLGLKERSTSEPAVPPEEAEPHTEPEEQV 120
Query: 121 PVEAEPQNIEDEAKEQIQSLLHEMVHAEHVEGEDLQQEDGPTGEPQQEDDEFLMATDVDD 180
PVEAEPQNIEDEAKEQIQSLLHEMVHAEHVEGEDLQQEDGPTGEPQQEDDEFLMATDVDD
Sbjct: 121 PVEAEPQNIEDEAKEQIQSLLHEMVHAEHVEGEDLQQEDGPTGEPQQEDDEFLMATDVDD 180
Query: 181 RFETLEPEVSHEETEHSYHVEETVSQDCNQDMEEMMSEQENPDSSEPVVEDERLHHDTDD 240
RFETLEPEVSHEETEHSYHVEETVSQDCNQDMEEMMSEQENPDSSEPVVEDERLHHDTDD
Sbjct: 181 RFETLEPEVSHEETEHSYHVEETVSQDCNQDMEEMMSEQENPDSSEPVVEDERLHHDTDD 240
Query: 241 VTYQVYEEQAVYEPLENEGIEITEVTAPPEDNPVEDSQVIVEEVSIFPVEEQQEVPPDT 299
VTYQVYEEQAVYEPLENEGIEITEVTAPPEDNPVEDSQVIVEEVSIFPVEEQQEVPPDT
Sbjct: 241 VTYQVYEEQAVYEPLENEGIEITEVTAPPEDNPVEDSQVIVEEVSIFPVEEQQEVPPDT 299
>gi|14589860 aspartate beta-hydroxylase isoform c [Homo sapiens]
Length = 313
Score = 564 bits (1453), Expect = e-161
Identities = 279/295 (94%), Positives = 280/295 (94%), Gaps = 15/295 (5%)
Query: 5 KETKHGGHKNGRKGGLSGTSFFTWFMVIALLGVWTSVAVVWFDLVDYEEVLAKAKDFRYN 64
+ETKHGGHKNGRKGGLSGTSFFTWFMVIALLGVWTSVAVVWFDLVDYEEVL
Sbjct: 34 RETKHGGHKNGRKGGLSGTSFFTWFMVIALLGVWTSVAVVWFDLVDYEEVL--------- 84
Query: 65 LSEVLQGKLGIYDADGDGDFDVDDAKVLLGLKERSTSEPAVPPEEAEPHTEPEEQVPVEA 124
GKLGIYDADGDGDFDVDDAKVLLGLKERSTSEPAVPPEEAEPHTEPEEQVPVEA
Sbjct: 85 ------GKLGIYDADGDGDFDVDDAKVLLGLKERSTSEPAVPPEEAEPHTEPEEQVPVEA 138
Query: 125 EPQNIEDEAKEQIQSLLHEMVHAEHVEGEDLQQEDGPTGEPQQEDDEFLMATDVDDRFET 184
EPQNIEDEAKEQIQSLLHEMVHAEHVEGEDLQQEDGPTGEPQQEDDEFLMATDVDDRFET
Sbjct: 139 EPQNIEDEAKEQIQSLLHEMVHAEHVEGEDLQQEDGPTGEPQQEDDEFLMATDVDDRFET 198
Query: 185 LEPEVSHEETEHSYHVEETVSQDCNQDMEEMMSEQENPDSSEPVVEDERLHHDTDDVTYQ 244
LEPEVSHEETEHSYHVEETVSQDCNQDMEEMMSEQENPDSSEPVVEDERLHHDTDDVTYQ
Sbjct: 199 LEPEVSHEETEHSYHVEETVSQDCNQDMEEMMSEQENPDSSEPVVEDERLHHDTDDVTYQ 258
Query: 245 VYEEQAVYEPLENEGIEITEVTAPPEDNPVEDSQVIVEEVSIFPVEEQQEVPPDT 299
VYEEQAVYEPLENEGIEITEVTAPPEDNPVEDSQVIVEEVSIFPVEEQQEVPPDT
Sbjct: 259 VYEEQAVYEPLENEGIEITEVTAPPEDNPVEDSQVIVEEVSIFPVEEQQEVPPDT 313
>gi|14589866 aspartate beta-hydroxylase isoform a [Homo sapiens]
Length = 758
Score = 562 bits (1449), Expect = e-160
Identities = 278/295 (94%), Positives = 280/295 (94%), Gaps = 15/295 (5%)
Query: 5 KETKHGGHKNGRKGGLSGTSFFTWFMVIALLGVWTSVAVVWFDLVDYEEVLAKAKDFRYN 64
+ETKHGGHKNGRKGGLSGTSFFTWFMVIALLGVWTSVAVVWFDLVDYEEVL
Sbjct: 34 RETKHGGHKNGRKGGLSGTSFFTWFMVIALLGVWTSVAVVWFDLVDYEEVL--------- 84
Query: 65 LSEVLQGKLGIYDADGDGDFDVDDAKVLLGLKERSTSEPAVPPEEAEPHTEPEEQVPVEA 124
GKLGIYDADGDGDFDVDDAKVLLGLKERSTSEPAVPPEEAEPHTEPEEQVPVEA
Sbjct: 85 ------GKLGIYDADGDGDFDVDDAKVLLGLKERSTSEPAVPPEEAEPHTEPEEQVPVEA 138
Query: 125 EPQNIEDEAKEQIQSLLHEMVHAEHVEGEDLQQEDGPTGEPQQEDDEFLMATDVDDRFET 184
EPQNIEDEAKEQIQSLLHEMVHAEHVEGEDLQQEDGPTGEPQQEDDEFLMATDVDDRFET
Sbjct: 139 EPQNIEDEAKEQIQSLLHEMVHAEHVEGEDLQQEDGPTGEPQQEDDEFLMATDVDDRFET 198
Query: 185 LEPEVSHEETEHSYHVEETVSQDCNQDMEEMMSEQENPDSSEPVVEDERLHHDTDDVTYQ 244
LEPEVSHEETEHSYHVEETVSQDCNQDMEEMMSEQENPDSSEPVVEDERLHHDTDDVTYQ
Sbjct: 199 LEPEVSHEETEHSYHVEETVSQDCNQDMEEMMSEQENPDSSEPVVEDERLHHDTDDVTYQ 258
Query: 245 VYEEQAVYEPLENEGIEITEVTAPPEDNPVEDSQVIVEEVSIFPVEEQQEVPPDT 299
VYEEQAVYEPLENEGIEITEVTAPPEDNPVEDSQVIVEEVSIFPVEEQQEVPP+T
Sbjct: 259 VYEEQAVYEPLENEGIEITEVTAPPEDNPVEDSQVIVEEVSIFPVEEQQEVPPET 313
>gi|9910364 aspartate beta-hydroxylase isoform e [Homo sapiens]
Length = 225
Score = 203 bits (516), Expect = 2e-52
Identities = 107/175 (61%), Positives = 128/175 (73%), Gaps = 10/175 (5%)
Query: 1 MAEDKETKHGGHKNGRKGGLSGTSFFTWFMVIALLGVWTSVAVVWFDLVDYEEVLAKAKD 60
MAEDKETKHGGHKNGRKGGLSGTSFFTWFMVIALLGVWTSVAVVWFDLVDYEEVLAKAKD
Sbjct: 1 MAEDKETKHGGHKNGRKGGLSGTSFFTWFMVIALLGVWTSVAVVWFDLVDYEEVLAKAKD 60
Query: 61 FRYNLSEVLQGKLGIYDADGDGDFDVDDAKVLL----GLKERSTSEPAVPPEEAEPHTEP 116
FRYNLSEVLQGKLGIYDADGDGDFDVDDAKVLL G+ +R T A E + +
Sbjct: 61 FRYNLSEVLQGKLGIYDADGDGDFDVDDAKVLLEGPSGVAKRKTK--AKVKELTKEELKK 118
Query: 117 EEQVPVEAEPQNIEDEAKEQIQSLLHEMVHAEHVEGEDLQQEDGPTGEPQQEDDE 171
E++ P + E+ K + + + + + + DL +++ P G+ +E ++
Sbjct: 119 EKEKPESRKESKNEERKKGKKEDVRKD----KKIADADLSRKESPKGKKDREKEK 169
>gi|14589862 aspartate beta-hydroxylase isoform d [Homo sapiens]
Length = 210
Score = 164 bits (416), Expect = 7e-41
Identities = 92/175 (52%), Positives = 113/175 (64%), Gaps = 25/175 (14%)
Query: 1 MAEDKETKHGGHKNGRKGGLSGTSFFTWFMVIALLGVWTSVAVVWFDLVDYEEVLAKAKD 60
MAEDKETKHGGHKNGRKGGLSGTSFFTWFMVIALLGVWTSVAVVWFDLVDYEEVL
Sbjct: 1 MAEDKETKHGGHKNGRKGGLSGTSFFTWFMVIALLGVWTSVAVVWFDLVDYEEVL----- 55
Query: 61 FRYNLSEVLQGKLGIYDADGDGDFDVDDAKVLL----GLKERSTSEPAVPPEEAEPHTEP 116
GKLGIYDADGDGDFDVDDAKVLL G+ +R T A E + +
Sbjct: 56 ----------GKLGIYDADGDGDFDVDDAKVLLEGPSGVAKRKTK--AKVKELTKEELKK 103
Query: 117 EEQVPVEAEPQNIEDEAKEQIQSLLHEMVHAEHVEGEDLQQEDGPTGEPQQEDDE 171
E++ P + E+ K + + + + + + DL +++ P G+ +E ++
Sbjct: 104 EKEKPESRKESKNEERKKGKKEDVRKD----KKIADADLSRKESPKGKKDREKEK 154
>gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 52.4 bits (124), Expect = 5e-07
Identities = 52/228 (22%), Positives = 92/228 (40%), Gaps = 55/228 (24%)
Query: 108 EEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQSLLHEMVHAEHVEGEDLQQEDGPTGEPQQ 167
+E+E EP+E +P + +E KE+ + + E AE E ED + P P
Sbjct: 1205 QESEETVEPKEDMP-------LPEERKEE-EEMQAEAEEAEEGEEEDAASSEVPAASPAD 1256
Query: 168 EDDEFLMATDVDDRFETLEPEVSHEETEHSYHVEETVSQDCNQDMEEMMSEQENPDSSEP 227
+ ET EPEV EE + E+ S++ Q++EE E+E ++E
Sbjct: 1257 SSNS--------PETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAET 1308
Query: 228 VVEDERLHHDTDD-----VTYQVYEEQAVYEPLENE-GIEITEVTA-------------- 267
D+ D DD + EEQ E ++ E G++ + + A
Sbjct: 1309 AQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEE 1368
Query: 268 ----PPEDNPVEDSQVIVEEVS---------------IFPVEEQQEVP 296
E+ P D+ V+ E+++ + ++E++E+P
Sbjct: 1369 TELDSEEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIP 1416
Score = 48.1 bits (113), Expect = 9e-06
Identities = 50/198 (25%), Positives = 85/198 (42%), Gaps = 24/198 (12%)
Query: 97 ERSTSEPAVPPEEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQSLLHEMVHAEHVEGEDLQ 156
E T EP V EE +P EEQ E E Q +E+ E+ E AE + +D
Sbjct: 1262 ETETKEPEVEEEEEKPRVS-EEQRQSEEEQQELEEPEPEE-----EEDAAAETAQNDDHD 1315
Query: 157 QEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEETEHSYHVEETVSQDCNQDMEEMM 216
+D EDD L +T + + LE + + E+ + V+E+ Q E +
Sbjct: 1316 ADD--------EDDGHLEST----KKKELEEQPTREDVKEEPGVQESFLDANMQKSREKI 1363
Query: 217 SEQENPDSSEPVVEDERLHHDTDDVTYQVYEEQAVYEPLENEGIEITEVTAPPEDNPVED 276
++E + E+E+ HDT V+ Q+ + +E + E+ E+ E+ +
Sbjct: 1364 KDKEETELDS---EEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIEL---KEEEEIPH 1417
Query: 277 SQVIVEEVSIFPVEEQQE 294
S++ +E V Q+E
Sbjct: 1418 SELDLETVQAVQSLTQEE 1435
>gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 52.4 bits (124), Expect = 5e-07
Identities = 52/228 (22%), Positives = 92/228 (40%), Gaps = 55/228 (24%)
Query: 108 EEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQSLLHEMVHAEHVEGEDLQQEDGPTGEPQQ 167
+E+E EP+E +P + +E KE+ + + E AE E ED + P P
Sbjct: 1205 QESEETVEPKEDMP-------LPEERKEE-EEMQAEAEEAEEGEEEDAASSEVPAASPAD 1256
Query: 168 EDDEFLMATDVDDRFETLEPEVSHEETEHSYHVEETVSQDCNQDMEEMMSEQENPDSSEP 227
+ ET EPEV EE + E+ S++ Q++EE E+E ++E
Sbjct: 1257 SSNS--------PETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAET 1308
Query: 228 VVEDERLHHDTDD-----VTYQVYEEQAVYEPLENE-GIEITEVTA-------------- 267
D+ D DD + EEQ E ++ E G++ + + A
Sbjct: 1309 AQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEE 1368
Query: 268 ----PPEDNPVEDSQVIVEEVS---------------IFPVEEQQEVP 296
E+ P D+ V+ E+++ + ++E++E+P
Sbjct: 1369 TELDSEEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIP 1416
Score = 48.1 bits (113), Expect = 9e-06
Identities = 50/198 (25%), Positives = 85/198 (42%), Gaps = 24/198 (12%)
Query: 97 ERSTSEPAVPPEEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQSLLHEMVHAEHVEGEDLQ 156
E T EP V EE +P EEQ E E Q +E+ E+ E AE + +D
Sbjct: 1262 ETETKEPEVEEEEEKPRVS-EEQRQSEEEQQELEEPEPEE-----EEDAAAETAQNDDHD 1315
Query: 157 QEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEETEHSYHVEETVSQDCNQDMEEMM 216
+D EDD L +T + + LE + + E+ + V+E+ Q E +
Sbjct: 1316 ADD--------EDDGHLEST----KKKELEEQPTREDVKEEPGVQESFLDANMQKSREKI 1363
Query: 217 SEQENPDSSEPVVEDERLHHDTDDVTYQVYEEQAVYEPLENEGIEITEVTAPPEDNPVED 276
++E + E+E+ HDT V+ Q+ + +E + E+ E+ E+ +
Sbjct: 1364 KDKEETELDS---EEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIEL---KEEEEIPH 1417
Query: 277 SQVIVEEVSIFPVEEQQE 294
S++ +E V Q+E
Sbjct: 1418 SELDLETVQAVQSLTQEE 1435
>gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 52.4 bits (124), Expect = 5e-07
Identities = 52/228 (22%), Positives = 92/228 (40%), Gaps = 55/228 (24%)
Query: 108 EEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQSLLHEMVHAEHVEGEDLQQEDGPTGEPQQ 167
+E+E EP+E +P + +E KE+ + + E AE E ED + P P
Sbjct: 1205 QESEETVEPKEDMP-------LPEERKEE-EEMQAEAEEAEEGEEEDAASSEVPAASPAD 1256
Query: 168 EDDEFLMATDVDDRFETLEPEVSHEETEHSYHVEETVSQDCNQDMEEMMSEQENPDSSEP 227
+ ET EPEV EE + E+ S++ Q++EE E+E ++E
Sbjct: 1257 SSNS--------PETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAET 1308
Query: 228 VVEDERLHHDTDD-----VTYQVYEEQAVYEPLENE-GIEITEVTA-------------- 267
D+ D DD + EEQ E ++ E G++ + + A
Sbjct: 1309 AQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEE 1368
Query: 268 ----PPEDNPVEDSQVIVEEVS---------------IFPVEEQQEVP 296
E+ P D+ V+ E+++ + ++E++E+P
Sbjct: 1369 TELDSEEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIP 1416
Score = 48.1 bits (113), Expect = 9e-06
Identities = 50/198 (25%), Positives = 85/198 (42%), Gaps = 24/198 (12%)
Query: 97 ERSTSEPAVPPEEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQSLLHEMVHAEHVEGEDLQ 156
E T EP V EE +P EEQ E E Q +E+ E+ E AE + +D
Sbjct: 1262 ETETKEPEVEEEEEKPRVS-EEQRQSEEEQQELEEPEPEE-----EEDAAAETAQNDDHD 1315
Query: 157 QEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEETEHSYHVEETVSQDCNQDMEEMM 216
+D EDD L +T + + LE + + E+ + V+E+ Q E +
Sbjct: 1316 ADD--------EDDGHLEST----KKKELEEQPTREDVKEEPGVQESFLDANMQKSREKI 1363
Query: 217 SEQENPDSSEPVVEDERLHHDTDDVTYQVYEEQAVYEPLENEGIEITEVTAPPEDNPVED 276
++E + E+E+ HDT V+ Q+ + +E + E+ E+ E+ +
Sbjct: 1364 KDKEETELDS---EEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIEL---KEEEEIPH 1417
Query: 277 SQVIVEEVSIFPVEEQQE 294
S++ +E V Q+E
Sbjct: 1418 SELDLETVQAVQSLTQEE 1435
>gi|17975763 myelin transcription factor 1 [Homo sapiens]
Length = 1121
Score = 48.9 bits (115), Expect = 5e-06
Identities = 37/142 (26%), Positives = 64/142 (45%), Gaps = 3/142 (2%)
Query: 105 VPPEEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQSLLHEMVHAEHVEGEDLQQEDGPTGE 164
+ PE+AE E + + PQ++ED A E+ + H E E E+ ++E+ E
Sbjct: 216 IQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDE 275
Query: 165 PQQEDDEFLMATDVDDRFETLEPEVSHEETEHSYHV--EETVSQDCNQDMEEMMS-EQEN 221
++E++E + ++ E E E EE E + V +E S Q E+ E +
Sbjct: 276 EEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPS 335
Query: 222 PDSSEPVVEDERLHHDTDDVTY 243
P V+ + R D D+ T+
Sbjct: 336 PKPEYSVIVEVRSDDDKDEDTH 357
Score = 35.0 bits (79), Expect = 0.080
Identities = 34/153 (22%), Positives = 63/153 (41%), Gaps = 15/153 (9%)
Query: 144 MVHAEHVEGEDLQQEDGPTG---EPQQEDDEFLMATDVDDRF--ETLEPEVSHEETEHS- 197
+VH E E+G G +P+ ++ + T+ ++LE S E ++
Sbjct: 194 IVHLLQEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKG 253
Query: 198 --YHVEETVSQDCNQDMEEMMSEQENPDSSEPVVEDERLHHDTDDVTYQVYEEQAVYEPL 255
H EE ++ ++ EE E+E + E E+E + ++ + EE+A + +
Sbjct: 254 ILSHEEEDEEEE-EEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVI 312
Query: 256 ENEGIEIT------EVTAPPEDNPVEDSQVIVE 282
E T E+ P +P + VIVE
Sbjct: 313 FQEDTSHTSAQKAPELRGPESPSPKPEYSVIVE 345
Score = 33.9 bits (76), Expect = 0.18
Identities = 61/266 (22%), Positives = 105/266 (39%), Gaps = 42/266 (15%)
Query: 52 EEVLAKAKDFRYNLSEVLQGKLGIYDADGDGDFDVDDAKV-------LLGLKERSTSEPA 104
E +++K K L+ L G+ D+DG D +V DA V L G + ++ +
Sbjct: 68 EHLVSKRKSHPLKLA--LDEGYGV-DSDGSEDTEVKDASVSDESEGTLEGAEAETSGQDE 124
Query: 105 VP-PEEAEPHTEPEEQV---PVEAEPQNIEDEAKEQIQSLLHEMVHAEHVEGEDLQQED- 159
+ PE AE + + P+ + + + + +++ + E L +ED
Sbjct: 125 IHRPETAEGRSPVKSHFGSNPIGSATASSKGSYSSYQGIIATSLLNLGQIAEETLVEEDL 184
Query: 160 GPTGEPQQEDDEFLM------ATDVDDRFETLEPEVSHEETEHSYHVEETVSQD-CNQDM 212
G +P L A++ ++ ++PE + E E V SQD C Q +
Sbjct: 185 GQAAKPGPGIVHLLQEAAEGAASEEGEKGLFIQPEDAEEVVE----VTTERSQDLCPQSL 240
Query: 213 EEMMSEQENPDSSEPVVEDERLHHDTDDVTYQVYEEQAVYEPLENEGIEITEVTAPPEDN 272
E+ SE+ + L H+ +D EE+ E E E E E E+
Sbjct: 241 EDAASEESSKQKGI-------LSHEEED------EEEEEEEEEEEEDEEEEEEEEEEEEE 287
Query: 273 PVEDSQVIVEEVSIFPVEEQQEVPPD 298
E+ + EE EE++E PD
Sbjct: 288 EEEEEE---EEEEEEEEEEEEEAAPD 310
Score = 32.0 bits (71), Expect = 0.68
Identities = 35/169 (20%), Positives = 60/169 (35%), Gaps = 10/169 (5%)
Query: 86 VDDAKVLLGLKERSTSEPAVPPEEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQSLLHEMV 145
++DA K++ EE E E EE+ E E + E+E +E+
Sbjct: 240 LEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEE--------- 290
Query: 146 HAEHVEGEDLQQEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEETEHSYHVEETVS 205
E E E+ ++E+ P E T E PE + E+S VE
Sbjct: 291 -EEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPEYSVIVEVRSD 349
Query: 206 QDCNQDMEEMMSEQENPDSSEPVVEDERLHHDTDDVTYQVYEEQAVYEP 254
D ++D S + + ++ L + + + + V EP
Sbjct: 350 DDKDEDTHSRKSTVTDESEMQDMMTRGNLGLLEQAIALKAEQVRTVCEP 398
>gi|104526627 triadin [Homo sapiens]
Length = 729
Score = 47.0 bits (110), Expect = 2e-05
Identities = 34/144 (23%), Positives = 63/144 (43%), Gaps = 25/144 (17%)
Query: 28 WFMVIALLGVWTSVAVVWFDLVDYE-------------------EVLAKAKDFRYNLSEV 68
W +VIAL+ W++VA+V FDLVDY+ + + + D+ Y +
Sbjct: 50 WLLVIALIITWSAVAIVMFDLVDYKNFSASSIAKIGSDPLKLVRDAMEETTDWIYGFFSL 109
Query: 69 LQGKLGIYD-ADGDGDFDVDDAKVLLGLKERSTSEPAVPPEEAEPHTEPEEQVPVEAEPQ 127
L + D D DGD D D ++ E + + ++ E +PE ++ + +
Sbjct: 110 LSDIISSEDEEDDDGDEDTDKGEI----DEPPLRKKEIHKDKTEKQEKPERKIQTKVTHK 165
Query: 128 NIEDEAKEQIQSLLHEMVHAEHVE 151
+++ KE+++ A H E
Sbjct: 166 E-KEKGKEKVREKEKPEKKATHKE 188
Score = 32.7 bits (73), Expect = 0.40
Identities = 38/160 (23%), Positives = 65/160 (40%), Gaps = 15/160 (9%)
Query: 88 DAKVLLGLKERSTSEPAVPPEEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQSLLHEMVHA 147
+AK + K + + V PE+ H +PEE+V + + IE AK + A
Sbjct: 529 EAKPAISEKVQIHKQDIVKPEKTVSHGKPEEKVLKQVKAVTIEKTAKPK------PTKKA 582
Query: 148 EHVEGEDLQ-QEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEETEHSYHVEETVSQ 206
EH E E + D P P+ + T+ + + + S E+ + + EE VS
Sbjct: 583 EHREREPPSIKTDKPKPTPKGTSE----VTESGKKKTEISEKESKEKADMKHLREEKVST 638
Query: 207 DCNQDMEEMMSEQENPDSSEPVVED----ERLHHDTDDVT 242
+++ E P VED ++ T+DV+
Sbjct: 639 RKESLQLHNVTKAEKPARVSKDVEDVPASKKAKEGTEDVS 678
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 44.7 bits (104), Expect = 1e-04
Identities = 33/158 (20%), Positives = 76/158 (48%), Gaps = 9/158 (5%)
Query: 79 DGDGDFDVDDAKVLLGLKERSTSEPAVPPEEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQ 138
D + + +++ +V+ LK R +EA+ +P+E+ + + E+ E+++
Sbjct: 2177 DDEEEGGIEEEEVIPFLKRRWRKR-----KEAKRGDKPKEKFSSQVDEVESEEHFSEEME 2231
Query: 139 SLLHEMVHAEHVEGEDLQQ----EDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEET 194
SLL E+ E + E+ ++ E+ E ++E++E + +++ E E ++
Sbjct: 2232 SLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKK 2291
Query: 195 EHSYHVEETVSQDCNQDMEEMMSEQENPDSSEPVVEDE 232
+ E ++ ++ EE+MSE+E S+ E+E
Sbjct: 2292 KEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEE 2329
Score = 41.2 bits (95), Expect = 0.001
Identities = 44/203 (21%), Positives = 85/203 (41%), Gaps = 11/203 (5%)
Query: 95 LKERSTSEPAVPPEEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQSLLHEMVHAEHVEGED 154
++ E + EE++ + E + + E IE+E E I L + + D
Sbjct: 2150 MRRMINKEEKMTEEESKLARKHSEVILDDEEEGGIEEE--EVIPFLKRRWRKRKEAKRGD 2207
Query: 155 LQQEDGPTGEPQQEDDEFLMATDVDDRFETLEPE--VSHEETEHSYHVEETVSQDCNQDM 212
+E + + E +E + +++ + LE + +S EE E EE ++ ++
Sbjct: 2208 KPKEKFSSQVDEVESEEHF-SEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEE 2266
Query: 213 EEMMSEQENPDSSEPVVEDERLHHDTDDVTYQVYEEQAVYEPLENEGIEITEVTAPPEDN 272
EE E+E + E+E+ + +V E++ V+E E E I E T D
Sbjct: 2267 EERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFE--EKEEIMSEEETESLSDE 2324
Query: 273 PVEDSQVIVEEVSIFPVEEQQEV 295
E+ +EE V+ ++E+
Sbjct: 2325 EEEEESCSLEE----EVDREKEI 2343
Score = 33.1 bits (74), Expect = 0.31
Identities = 39/135 (28%), Positives = 59/135 (43%), Gaps = 21/135 (15%)
Query: 87 DDAKVLLGLKERSTSEPAVPPEEAEPHTE-PEEQVPVEAEPQNIEDEAKEQIQSLLHEMV 145
++ + LL E+ S + EE E E EE+V E E + E+E +E+
Sbjct: 2228 EEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEK--------- 2278
Query: 146 HAEHVEGEDLQQEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEETEHSYHVEETVS 205
E E E +++ E QE +E FE E +S EETE S EE
Sbjct: 2279 QVEKEEEEKKKKKKEKKKEEVQEKEEV---------FEEKEEIMSEEETE-SLSDEEEEE 2328
Query: 206 QDCNQDMEEMMSEQE 220
+ C+ + EE+ E+E
Sbjct: 2329 ESCSLE-EEVDREKE 2342
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 44.7 bits (104), Expect = 1e-04
Identities = 48/205 (23%), Positives = 80/205 (39%), Gaps = 16/205 (7%)
Query: 77 DADGDGDFDVDDAKVLLGLKERSTSEPAVPPEEAEPHTEPEEQVPVEAEPQNIEDEAKEQ 136
+A+G+ + +D + E V EAE +PE + AE E EA+ +
Sbjct: 1862 EAEGEAQPESEDVEAPEAEGEAQPESEDVETPEAEWEVQPESE---GAEAPEAEKEAQPE 1918
Query: 137 IQSLLHEMVHAEHVEGEDLQQEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEETEH 196
+S V A EGED + +G + +E + E +E + + EE +
Sbjct: 1919 TES-----VEALETEGEDEPESEGAEAQEAEEAAQEAEG-QTQPESEVIESQEAEEEAQP 1972
Query: 197 SYHVEETVSQDCNQDMEEMMSEQENPDSSEPVVE------DERLHHDTDDVTYQVYEEQA 250
E + + E ++ E+ D P E +E ++D V Q E
Sbjct: 1973 ESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGE 2032
Query: 251 VYEPLENEGIEITEVTAPPEDNPVE 275
+ +E E + TE A PE + VE
Sbjct: 2033 EAQEVEGE-TQKTEGDAQPESDGVE 2056
Score = 43.5 bits (101), Expect = 2e-04
Identities = 51/211 (24%), Positives = 86/211 (40%), Gaps = 32/211 (15%)
Query: 108 EEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQSLLHEMVHAEHVEGEDLQQEDGPTGEPQQ 167
+EAE T+PE +V E Q E+EA+ + + + E +E E QE +P+
Sbjct: 1948 QEAEGQTQPESEV---IESQEAEEEAQPESEDV-------EALEVEVETQEAEGEAQPES 1997
Query: 168 EDDEFLMAT-DVDDRFETLEPEVSHEETEHSYHVEETVSQDCNQDMEEMMSEQENPDSSE 226
ED E A ++ + E +PE E + EE + E ++ E+
Sbjct: 1998 EDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEA 2057
Query: 227 PVVEDE-------------RLHHDTDDVTYQVYEEQAVYEPLENEGIEITEVTAPPE--- 270
P E+E H +++DV Q E +A +P E+EG+E E +
Sbjct: 2058 PEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEA--QP-ESEGVEAPEAEGEAQKAE 2114
Query: 271 --DNPVEDSQVIVEEVSIFPVEEQQEVPPDT 299
+ P + + E I E + E P++
Sbjct: 2115 GIEAPETEGEAQPESEGIEAPEAEGEAQPES 2145
Score = 40.0 bits (92), Expect = 0.002
Identities = 48/203 (23%), Positives = 81/203 (39%), Gaps = 26/203 (12%)
Query: 104 AVPPEEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQSLLHEMVHAEHVEGEDLQQEDGPTG 163
A E E + EEQ N+E A+ +Q + E EGE LQ+E
Sbjct: 1268 ACATNEDEAERDSEEQ----RASSNLEQLAENTVQEEVQLEETKEGTEGEGLQEEAVQLE 1323
Query: 164 EPQQEDDEFLMATDVDDRFETLEPEVSHEETEHSYHVEETVSQDCNQDMEEMMSEQENPD 223
E + E+ +++ ET E E EE +EET + ++ ++ +E P+
Sbjct: 1324 ETKTEEGLQEEGVQLEETKET-EGEGQQEEEAQLEEIEETGGEGLQEEGVQLEEVKEGPE 1382
Query: 224 SSEPVVEDERLHHDTDDVTYQVYEEQAVYEPLENEGIEITEVTAP-----PEDNPVEDSQ 278
++ E L + +E+ + E G E++E ++P ED+PV++ +
Sbjct: 1383 GG---LQGEALE--------EGLKEEGLPEEGSVHGQELSEASSPDGKGSQEDDPVQEEE 1431
Query: 279 VIVEEVSIFP-----VEEQQEVP 296
S P EE E P
Sbjct: 1432 AGRASASAEPCPAEGTEEPTEPP 1454
Score = 39.7 bits (91), Expect = 0.003
Identities = 55/219 (25%), Positives = 83/219 (37%), Gaps = 22/219 (10%)
Query: 98 RSTSEPAVPPEEAEPHTEPE----EQVPVEAEPQNIEDEAKEQIQSLLHEMVHAEHVEGE 153
+S + EAE +PE E E + Q E EA+ + E V A EGE
Sbjct: 1828 QSDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPE-----SEDVEAPEAEGE 1882
Query: 154 -DLQQEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEETEHSYHVEETVSQDCN-QD 211
+ ED T E + E + + + +PE E + +E S+ Q+
Sbjct: 1883 AQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQE 1942
Query: 212 MEEMMSEQENPDSSE-PVVEDERLHHDTDDVTYQVYEEQAVYEPLENEG---IEITEVTA 267
EE E E E V+E + + + V + E E EG E +V A
Sbjct: 1943 AEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEA 2002
Query: 268 PPEDNPV----EDSQVIVEEVSIFPV---EEQQEVPPDT 299
P + + E++Q + V P EE QEV +T
Sbjct: 2003 PEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGET 2041
Score = 38.9 bits (89), Expect = 0.006
Identities = 57/244 (23%), Positives = 89/244 (36%), Gaps = 33/244 (13%)
Query: 79 DGDGDFDVDDAKVLLGLKERSTSEPAVPPEEAEPHTEPE----EQVPVEAEPQNIEDEAK 134
+GD + D + +E +E V E E H E E ++ EA+P++ EA
Sbjct: 2045 EGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAP 2104
Query: 135 E-QIQSLLHEMVHAEHVEGEDLQQEDG-----PTGEPQQEDDEFLMATDVDDRFETLEPE 188
E + ++ E + A EGE + +G GE Q E + + D +PE
Sbjct: 2105 EAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESE----GVEAQDAEGEAQPE 2160
Query: 189 VSHEETEHSYHVEETVSQDCNQDMEEMMSEQENPDSSEPVVEDERLHHDTDDVTYQVYEE 248
E + + + + E ++ E+ P E E + + V EE
Sbjct: 2161 SEGIEAQEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGE-AQPELEGVEAPEAEE 2219
Query: 249 QAVYEPLENEGIEITEV--TAPPEDN-------------PVEDSQVIVEEVSIFPVEEQQ 293
+A EP EG+E E A PE + D Q S PV E +
Sbjct: 2220 EAQPEP---EGVETPEAEGEAQPESEGETQGEKKGSPQVSLGDGQSEEASESSSPVPEDR 2276
Query: 294 EVPP 297
PP
Sbjct: 2277 PTPP 2280
Score = 32.3 bits (72), Expect = 0.52
Identities = 41/162 (25%), Positives = 61/162 (37%), Gaps = 39/162 (24%)
Query: 97 ERSTSEPAVPPEEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQS----------------- 139
E E V EE + TE E Q EA+ + IE+ E +Q
Sbjct: 1328 EEGLQEEGVQLEETK-ETEGEGQQEEEAQLEEIEETGGEGLQEEGVQLEEVKEGPEGGLQ 1386
Query: 140 --LLHEMVHAE------HVEGEDLQQEDGPTGEPQQEDDEFLMATDVDDRFETLEP---E 188
L E + E V G++L + P G+ QEDD + + + EP E
Sbjct: 1387 GEALEEGLKEEGLPEEGSVHGQELSEASSPDGKGSQEDDP-VQEEEAGRASASAEPCPAE 1445
Query: 189 VSHEETEHSYHVEETVSQDCNQDMEEMMSEQENPDSSEPVVE 230
+ E TE H+ ET + SE+++ EP +E
Sbjct: 1446 GTEEPTEPPSHLSET---------DPSASERQSGSQLEPGLE 1478
>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
Length = 770
Score = 43.5 bits (101), Expect = 2e-04
Identities = 35/149 (23%), Positives = 61/149 (40%), Gaps = 30/149 (20%)
Query: 148 EHVEGEDLQQEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEETEHSYHVEETVSQD 207
E E E+ ++E+G T E +E++E E EE E + EE Q
Sbjct: 280 EEEEEEEEEEEEGSTSEESEEEEE----------------EEEEEEEETGSNSEEASEQS 323
Query: 208 CNQDMEEMMSEQENPDSSEPVVEDERLHHDTDDVTYQVYEEQAVYEPLENEGIEITEVTA 267
+ EE MSE E ++ ++ D D + EE E+ E T
Sbjct: 324 AEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEE------------EVGEGT- 370
Query: 268 PPEDNPVEDSQVIVEEVSIFPVEEQQEVP 296
P+ + + + + + ++ P+E +QE+P
Sbjct: 371 -PQSSALTEGDYVPDSPALLPIELKQELP 398
Score = 33.5 bits (75), Expect = 0.23
Identities = 24/110 (21%), Positives = 48/110 (43%), Gaps = 1/110 (0%)
Query: 85 DVDDAKVLLGLKERSTSEPAV-PPEEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQSLLHE 143
D+ D++ E S++E EE E E EE+ E + E+E +E+ +
Sbjct: 256 DISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSN 315
Query: 144 MVHAEHVEGEDLQQEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEE 193
A E++ +E+ E ++ ++ L+ + ++ E E + EE
Sbjct: 316 SEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEE 365
>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
Length = 780
Score = 43.5 bits (101), Expect = 2e-04
Identities = 35/149 (23%), Positives = 61/149 (40%), Gaps = 30/149 (20%)
Query: 148 EHVEGEDLQQEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEETEHSYHVEETVSQD 207
E E E+ ++E+G T E +E++E E EE E + EE Q
Sbjct: 290 EEEEEEEEEEEEGSTSEESEEEEE----------------EEEEEEEETGSNSEEASEQS 333
Query: 208 CNQDMEEMMSEQENPDSSEPVVEDERLHHDTDDVTYQVYEEQAVYEPLENEGIEITEVTA 267
+ EE MSE E ++ ++ D D + EE E+ E T
Sbjct: 334 AEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEE------------EVGEGT- 380
Query: 268 PPEDNPVEDSQVIVEEVSIFPVEEQQEVP 296
P+ + + + + + ++ P+E +QE+P
Sbjct: 381 -PQSSALTEGDYVPDSPALLPIELKQELP 408
Score = 33.5 bits (75), Expect = 0.23
Identities = 24/110 (21%), Positives = 48/110 (43%), Gaps = 1/110 (0%)
Query: 85 DVDDAKVLLGLKERSTSEPAV-PPEEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQSLLHE 143
D+ D++ E S++E EE E E EE+ E + E+E +E+ +
Sbjct: 266 DISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSN 325
Query: 144 MVHAEHVEGEDLQQEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEE 193
A E++ +E+ E ++ ++ L+ + ++ E E + EE
Sbjct: 326 SEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEE 375
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 42.7 bits (99), Expect = 4e-04
Identities = 58/236 (24%), Positives = 96/236 (40%), Gaps = 34/236 (14%)
Query: 86 VDDAKVLLGLKERSTSEPAVP-------PEEAEPHTEPEEQVP----VEAEPQNIEDEAK 134
V + K+ + + + PAVP PEE +P EE+VP V A P+ E K
Sbjct: 9380 VTEEKITIVTQREESPPPAVPEIPKKKVPEERKPVPRKEEEVPPPPKVPALPKKPVPEEK 9439
Query: 135 EQIQSLLHEMVHAEHVEGEDLQQEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEET 194
+ + + E E ++ E ++ V R E EVS EE
Sbjct: 9440 VAVPVPVAKKAPPPRAE-----VSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEVSAEEE 9494
Query: 195 EHSYHVEETVS------QDCNQDMEEMMSEQENPDSSEPVVEDERLH-------HDTDDV 241
EE VS ++ ++ E ++E E + E V +E+LH + +V
Sbjct: 9495 WSYSEEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVEAEPAEV 9554
Query: 242 TYQVYEEQAVYEPLENEGIEITEVTAPPEDNPVEDSQVIVEEVSIFPVEEQQEVPP 297
T + E++ V +P IE PP P +++ E+ PV ++++VPP
Sbjct: 9555 TER-QEKKIVLKPKIPAKIE----EPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPP 9605
Score = 41.2 bits (95), Expect = 0.001
Identities = 52/214 (24%), Positives = 88/214 (41%), Gaps = 40/214 (18%)
Query: 92 LLGLKERSTSEPAVPPEEAEPHTEPEEQVPVEA---EPQNIED----EAKEQIQSLLHEM 144
+L LK + EP E EE+V +EA EPQ I++ E KE+ +L E
Sbjct: 9677 VLKLKPKREEEPPAKVTEFRKRVVKEEKVSIEAPKREPQPIKEVTIMEEKERAYTLEEEA 9736
Query: 145 VHAEHVEG-EDLQQEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEETEHSYHVEET 203
V + E E+ ++ D E + +E+ D++E +EE E+ + E
Sbjct: 9737 VSVQREEEYEEYEEYDYKEFEEYEPTEEY-------DQYE------EYEEREYERYEEH- 9782
Query: 204 VSQDCNQDMEEMMSEQENPDSSEPVVED---ERLHHDTDDVTYQVYEEQAVYEPLENEGI 260
EE ++E E P +PV E+ + V + E+ V P+
Sbjct: 9783 ---------EEYITEPEKPIPVKPVPEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPK--- 9830
Query: 261 EITEVTAPPEDNPVEDSQVIVEEVSIFPVEEQQE 294
++ PP P E +V E++ I + ++E
Sbjct: 9831 ---KLKPPPPKVPEEPKKVFEEKIRISITKREKE 9861
Score = 41.2 bits (95), Expect = 0.001
Identities = 54/214 (25%), Positives = 95/214 (44%), Gaps = 27/214 (12%)
Query: 103 PAVP----PEEAEPHTEPEE------QVPVEAEPQNIEDEAKEQIQSLLHEMVHAEHVEG 152
P VP PEE +P P++ +VP + EP + ++ + L E + E
Sbjct: 10061 PEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEE--- 10117
Query: 153 EDLQQEDGPTGEPQQ---EDDEFLMATD-VDDRFETLEPEVSHEETEHSYHVEETVSQDC 208
E L +E+ E ++ E++E L + + E + PE + E + EE V +
Sbjct: 10118 EVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPEEEVLPEV 10177
Query: 209 NQDME--EMMSEQENPDSSEPVV---EDERLHHDTDDVTYQVYEEQAVYEPLENEGIEIT 263
+ + E + + + VV ++E +V +V EE+ + P E E + +
Sbjct: 10178 KPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKV-EEKRIILPKEEEVLPV- 10235
Query: 264 EVTAPPEDNPVEDSQVIVEEVSIFPVEEQQEVPP 297
EVT PE+ P+ + ++ E SI EE +EV P
Sbjct: 10236 EVTEEPEEEPISEEEIPEEPPSI---EEVEEVAP 10266
Score = 40.8 bits (94), Expect = 0.001
Identities = 40/195 (20%), Positives = 85/195 (43%), Gaps = 15/195 (7%)
Query: 109 EAEPHTEPEEQVPVEAEPQNIEDEAKEQIQSLLHEMVHAEHVEGEDLQQEDGPTGEPQQE 168
E EP+TEP EQ P EP +E K + + +HE + EG++ + + E ++E
Sbjct: 9081 EVEPYTEPFEQ-PYYEEPDEDYEEIKVEAKKEVHEEWEEDFEEGQEYYEREEGYDEGEEE 9139
Query: 169 DDEFLMATDVDDRFETLEPEVSHEETEHSYHVEETVSQDCNQDMEEMMSEQ--ENPDSSE 226
+E +V ++ + E H V V + +++ + E + +
Sbjct: 9140 WEEAYQEREV------IQVQKEVYEESHERKVPAKVPEKKAPPPPKVIKKPVIEKIEKTS 9193
Query: 227 PVVEDERLH-HDTDDVTYQVYEEQAVYEPLENEGIEITEVTAPPEDNPVEDSQVIV---- 281
+E+E++ +V+ ++ ++ P++ E IE+ + + + ++
Sbjct: 9194 RRMEEEKVQVTKVPEVSKKIVPQKPSRTPVQEEVIEVKVPAVHTKKMVISEEKMFFASHT 9253
Query: 282 -EEVSIFPVEEQQEV 295
EEVS+ E Q+E+
Sbjct: 9254 EEEVSVTVPEVQKEI 9268
Score = 31.6 bits (70), Expect = 0.89
Identities = 41/209 (19%), Positives = 75/209 (35%), Gaps = 40/209 (19%)
Query: 96 KERSTSEPAVPPEEAEPHTEPEEQVPV------EAEPQNIEDEAKEQIQSLLHEMVHAEH 149
+E ++P PP + PEE+VPV + P + +E K+ + + +
Sbjct: 9800 EEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKLKPPPPKVPEEPKKVFEEKIRISITKRE 9859
Query: 150 VEGEDLQQEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEETEHSYHVEETV-SQDC 208
E Q P + + + V + + P V E EE ++
Sbjct: 9860 KE-----QVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPKELEPEEVAFEEEV 9914
Query: 209 NQDMEEMMSEQENPDSSEPVVEDERLHHDTDDVTYQVYEEQAVYEPLENEGIEITEVTAP 268
+EE + E+ E+E +H + + +T E+ V + + E+ P
Sbjct: 9915 VTHVEEYLVEE----------EEEYIHEEEEFIT-----EEEVVPVIPVKVPEVPRKPVP 9959
Query: 269 PEDNPVEDSQVIVEEVSIFPVEEQQEVPP 297
E PV PV +++E PP
Sbjct: 9960 EEKKPV-------------PVPKKKEAPP 9975
Score = 28.1 bits (61), Expect = 9.8
Identities = 21/59 (35%), Positives = 29/59 (49%), Gaps = 11/59 (18%)
Query: 90 KVLLGLKERSTSEPAVPP---EEAEPHTE--PEEQVPV------EAEPQNIEDEAKEQI 137
K+++ K R EP VPP E P E PE++VPV EA P + + KE +
Sbjct: 10475 KIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVV 10533
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 42.7 bits (99), Expect = 4e-04
Identities = 35/149 (23%), Positives = 61/149 (40%), Gaps = 30/149 (20%)
Query: 148 EHVEGEDLQQEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEETEHSYHVEETVSQD 207
E E E+ ++E+G T E +E++E E EE E + EE Q
Sbjct: 281 EEEEEEEEEEEEGSTSEESEEEEE----------------EEEEEEEETGSNSEEASEQS 324
Query: 208 CNQDMEEMMSEQENPDSSEPVVEDERLHHDTDDVTYQVYEEQAVYEPLENEGIEITEVTA 267
+ EE MSE E ++ ++ D D + EE E+ E T
Sbjct: 325 AEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEE------------EVGEGT- 371
Query: 268 PPEDNPVEDSQVIVEEVSIFPVEEQQEVP 296
P+ + + + + + ++ P+E +QE+P
Sbjct: 372 -PQSSALTEGDYVPDSPALSPIELKQELP 399
Score = 33.5 bits (75), Expect = 0.23
Identities = 24/110 (21%), Positives = 48/110 (43%), Gaps = 1/110 (0%)
Query: 85 DVDDAKVLLGLKERSTSEPAV-PPEEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQSLLHE 143
D+ D++ E S++E EE E E EE+ E + E+E +E+ +
Sbjct: 257 DISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSN 316
Query: 144 MVHAEHVEGEDLQQEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEE 193
A E++ +E+ E ++ ++ L+ + ++ E E + EE
Sbjct: 317 SEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEE 366
Score = 29.6 bits (65), Expect = 3.4
Identities = 33/149 (22%), Positives = 55/149 (36%), Gaps = 12/149 (8%)
Query: 80 GDGDFDVDDAKVLLGLKERSTSEPAVPPEEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQS 139
GDG V + K ++ER ++E T E E+ + E+E +E+ +
Sbjct: 235 GDGRKPVKEEK----MEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEE 290
Query: 140 LLHEMVHAEHVEGEDLQQEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSH-EETEHSY 198
E E+ ++E+ TG +E E E E E+S EE E+
Sbjct: 291 EEGSTSEESEEEEEEEEEEEEETGSNSEEASE-------QSAEEVSEEEMSEDEERENEN 343
Query: 199 HVEETVSQDCNQDMEEMMSEQENPDSSEP 227
H+ ++D E +E P
Sbjct: 344 HLLVVPESRFDRDSGESEEAEEEVGEGTP 372
>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
8 [Homo sapiens]
Length = 780
Score = 42.7 bits (99), Expect = 4e-04
Identities = 35/149 (23%), Positives = 61/149 (40%), Gaps = 30/149 (20%)
Query: 148 EHVEGEDLQQEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEETEHSYHVEETVSQD 207
E E E+ ++E+G T E +E++E E EE E + EE Q
Sbjct: 290 EEEEEEEEEEEEGSTSEESEEEEE----------------EEEEEEEETGSNSEEASEQS 333
Query: 208 CNQDMEEMMSEQENPDSSEPVVEDERLHHDTDDVTYQVYEEQAVYEPLENEGIEITEVTA 267
+ EE MSE E ++ ++ D D + EE E+ E T
Sbjct: 334 AEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEE------------EVGEGT- 380
Query: 268 PPEDNPVEDSQVIVEEVSIFPVEEQQEVP 296
P+ + + + + + ++ P+E +QE+P
Sbjct: 381 -PQSSALTEGDYVPDSPALSPIELKQELP 408
Score = 33.5 bits (75), Expect = 0.23
Identities = 24/110 (21%), Positives = 48/110 (43%), Gaps = 1/110 (0%)
Query: 85 DVDDAKVLLGLKERSTSEPAV-PPEEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQSLLHE 143
D+ D++ E S++E EE E E EE+ E + E+E +E+ +
Sbjct: 266 DISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSN 325
Query: 144 MVHAEHVEGEDLQQEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEE 193
A E++ +E+ E ++ ++ L+ + ++ E E + EE
Sbjct: 326 SEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEE 375
Score = 29.6 bits (65), Expect = 3.4
Identities = 33/149 (22%), Positives = 55/149 (36%), Gaps = 12/149 (8%)
Query: 80 GDGDFDVDDAKVLLGLKERSTSEPAVPPEEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQS 139
GDG V + K ++ER ++E T E E+ + E+E +E+ +
Sbjct: 244 GDGRKPVKEEK----MEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEE 299
Query: 140 LLHEMVHAEHVEGEDLQQEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSH-EETEHSY 198
E E+ ++E+ TG +E E E E E+S EE E+
Sbjct: 300 EEGSTSEESEEEEEEEEEEEEETGSNSEEASE-------QSAEEVSEEEMSEDEERENEN 352
Query: 199 HVEETVSQDCNQDMEEMMSEQENPDSSEP 227
H+ ++D E +E P
Sbjct: 353 HLLVVPESRFDRDSGESEEAEEEVGEGTP 381
>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
5 [Homo sapiens]
Length = 748
Score = 42.7 bits (99), Expect = 4e-04
Identities = 35/149 (23%), Positives = 61/149 (40%), Gaps = 30/149 (20%)
Query: 148 EHVEGEDLQQEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEETEHSYHVEETVSQD 207
E E E+ ++E+G T E +E++E E EE E + EE Q
Sbjct: 258 EEEEEEEEEEEEGSTSEESEEEEE----------------EEEEEEEETGSNSEEASEQS 301
Query: 208 CNQDMEEMMSEQENPDSSEPVVEDERLHHDTDDVTYQVYEEQAVYEPLENEGIEITEVTA 267
+ EE MSE E ++ ++ D D + EE E+ E T
Sbjct: 302 AEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEE------------EVGEGT- 348
Query: 268 PPEDNPVEDSQVIVEEVSIFPVEEQQEVP 296
P+ + + + + + ++ P+E +QE+P
Sbjct: 349 -PQSSALTEGDYVPDSPALSPIELKQELP 376
Score = 33.5 bits (75), Expect = 0.23
Identities = 24/110 (21%), Positives = 48/110 (43%), Gaps = 1/110 (0%)
Query: 85 DVDDAKVLLGLKERSTSEPAV-PPEEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQSLLHE 143
D+ D++ E S++E EE E E EE+ E + E+E +E+ +
Sbjct: 234 DISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSN 293
Query: 144 MVHAEHVEGEDLQQEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEE 193
A E++ +E+ E ++ ++ L+ + ++ E E + EE
Sbjct: 294 SEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEE 343
Score = 29.6 bits (65), Expect = 3.4
Identities = 33/149 (22%), Positives = 55/149 (36%), Gaps = 12/149 (8%)
Query: 80 GDGDFDVDDAKVLLGLKERSTSEPAVPPEEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQS 139
GDG V + K ++ER ++E T E E+ + E+E +E+ +
Sbjct: 212 GDGRKPVKEEK----MEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEE 267
Query: 140 LLHEMVHAEHVEGEDLQQEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSH-EETEHSY 198
E E+ ++E+ TG +E E E E E+S EE E+
Sbjct: 268 EEGSTSEESEEEEEEEEEEEEETGSNSEEASE-------QSAEEVSEEEMSEDEERENEN 320
Query: 199 HVEETVSQDCNQDMEEMMSEQENPDSSEP 227
H+ ++D E +E P
Sbjct: 321 HLLVVPESRFDRDSGESEEAEEEVGEGTP 349
>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
4 [Homo sapiens]
Length = 737
Score = 42.7 bits (99), Expect = 4e-04
Identities = 35/149 (23%), Positives = 61/149 (40%), Gaps = 30/149 (20%)
Query: 148 EHVEGEDLQQEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEETEHSYHVEETVSQD 207
E E E+ ++E+G T E +E++E E EE E + EE Q
Sbjct: 247 EEEEEEEEEEEEGSTSEESEEEEE----------------EEEEEEEETGSNSEEASEQS 290
Query: 208 CNQDMEEMMSEQENPDSSEPVVEDERLHHDTDDVTYQVYEEQAVYEPLENEGIEITEVTA 267
+ EE MSE E ++ ++ D D + EE E+ E T
Sbjct: 291 AEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEE------------EVGEGT- 337
Query: 268 PPEDNPVEDSQVIVEEVSIFPVEEQQEVP 296
P+ + + + + + ++ P+E +QE+P
Sbjct: 338 -PQSSALTEGDYVPDSPALSPIELKQELP 365
Score = 33.5 bits (75), Expect = 0.23
Identities = 24/110 (21%), Positives = 48/110 (43%), Gaps = 1/110 (0%)
Query: 85 DVDDAKVLLGLKERSTSEPAV-PPEEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQSLLHE 143
D+ D++ E S++E EE E E EE+ E + E+E +E+ +
Sbjct: 223 DISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSN 282
Query: 144 MVHAEHVEGEDLQQEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEE 193
A E++ +E+ E ++ ++ L+ + ++ E E + EE
Sbjct: 283 SEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEE 332
Score = 29.6 bits (65), Expect = 3.4
Identities = 33/149 (22%), Positives = 55/149 (36%), Gaps = 12/149 (8%)
Query: 80 GDGDFDVDDAKVLLGLKERSTSEPAVPPEEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQS 139
GDG V + K ++ER ++E T E E+ + E+E +E+ +
Sbjct: 201 GDGRKPVKEEK----MEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEE 256
Query: 140 LLHEMVHAEHVEGEDLQQEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSH-EETEHSY 198
E E+ ++E+ TG +E E E E E+S EE E+
Sbjct: 257 EEGSTSEESEEEEEEEEEEEEETGSNSEEASE-------QSAEEVSEEEMSEDEERENEN 309
Query: 199 HVEETVSQDCNQDMEEMMSEQENPDSSEP 227
H+ ++D E +E P
Sbjct: 310 HLLVVPESRFDRDSGESEEAEEEVGEGTP 338
>gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isoform
3 [Homo sapiens]
Length = 526
Score = 42.7 bits (99), Expect = 4e-04
Identities = 35/149 (23%), Positives = 61/149 (40%), Gaps = 30/149 (20%)
Query: 148 EHVEGEDLQQEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEETEHSYHVEETVSQD 207
E E E+ ++E+G T E +E++E E EE E + EE Q
Sbjct: 36 EEEEEEEEEEEEGSTSEESEEEEE----------------EEEEEEEETGSNSEEASEQS 79
Query: 208 CNQDMEEMMSEQENPDSSEPVVEDERLHHDTDDVTYQVYEEQAVYEPLENEGIEITEVTA 267
+ EE MSE E ++ ++ D D + EE E+ E T
Sbjct: 80 AEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEE------------EVGEGT- 126
Query: 268 PPEDNPVEDSQVIVEEVSIFPVEEQQEVP 296
P+ + + + + + ++ P+E +QE+P
Sbjct: 127 -PQSSALTEGDYVPDSPALSPIELKQELP 154
Score = 33.5 bits (75), Expect = 0.23
Identities = 24/110 (21%), Positives = 48/110 (43%), Gaps = 1/110 (0%)
Query: 85 DVDDAKVLLGLKERSTSEPAV-PPEEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQSLLHE 143
D+ D++ E S++E EE E E EE+ E + E+E +E+ +
Sbjct: 12 DISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSN 71
Query: 144 MVHAEHVEGEDLQQEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEE 193
A E++ +E+ E ++ ++ L+ + ++ E E + EE
Sbjct: 72 SEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEE 121
Score = 28.5 bits (62), Expect = 7.5
Identities = 31/132 (23%), Positives = 47/132 (35%), Gaps = 22/132 (16%)
Query: 97 ERSTSEPAVPPEEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQSLLHEMVHAEHVEGEDLQ 156
ER TS E+ +E EE+ E E + E E+ E E+ +
Sbjct: 17 ERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEE--------------EEEEEE 62
Query: 157 QEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSH-EETEHSYHVEETVSQDCNQDMEEM 215
+E+ TG +E E E E E+S EE E+ H+ ++D E
Sbjct: 63 EEEEETGSNSEEASE-------QSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGES 115
Query: 216 MSEQENPDSSEP 227
+E P
Sbjct: 116 EEAEEEVGEGTP 127
>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
2 [Homo sapiens]
Length = 782
Score = 42.7 bits (99), Expect = 4e-04
Identities = 35/149 (23%), Positives = 61/149 (40%), Gaps = 30/149 (20%)
Query: 148 EHVEGEDLQQEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEETEHSYHVEETVSQD 207
E E E+ ++E+G T E +E++E E EE E + EE Q
Sbjct: 292 EEEEEEEEEEEEGSTSEESEEEEE----------------EEEEEEEETGSNSEEASEQS 335
Query: 208 CNQDMEEMMSEQENPDSSEPVVEDERLHHDTDDVTYQVYEEQAVYEPLENEGIEITEVTA 267
+ EE MSE E ++ ++ D D + EE E+ E T
Sbjct: 336 AEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEE------------EVGEGT- 382
Query: 268 PPEDNPVEDSQVIVEEVSIFPVEEQQEVP 296
P+ + + + + + ++ P+E +QE+P
Sbjct: 383 -PQSSALTEGDYVPDSPALSPIELKQELP 410
Score = 33.5 bits (75), Expect = 0.23
Identities = 24/110 (21%), Positives = 48/110 (43%), Gaps = 1/110 (0%)
Query: 85 DVDDAKVLLGLKERSTSEPAV-PPEEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQSLLHE 143
D+ D++ E S++E EE E E EE+ E + E+E +E+ +
Sbjct: 268 DISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSN 327
Query: 144 MVHAEHVEGEDLQQEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEE 193
A E++ +E+ E ++ ++ L+ + ++ E E + EE
Sbjct: 328 SEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEE 377
Score = 29.6 bits (65), Expect = 3.4
Identities = 33/149 (22%), Positives = 55/149 (36%), Gaps = 12/149 (8%)
Query: 80 GDGDFDVDDAKVLLGLKERSTSEPAVPPEEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQS 139
GDG V + K ++ER ++E T E E+ + E+E +E+ +
Sbjct: 246 GDGRKPVKEEK----MEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEE 301
Query: 140 LLHEMVHAEHVEGEDLQQEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSH-EETEHSY 198
E E+ ++E+ TG +E E E E E+S EE E+
Sbjct: 302 EEGSTSEESEEEEEEEEEEEEETGSNSEEASE-------QSAEEVSEEEMSEDEERENEN 354
Query: 199 HVEETVSQDCNQDMEEMMSEQENPDSSEP 227
H+ ++D E +E P
Sbjct: 355 HLLVVPESRFDRDSGESEEAEEEVGEGTP 383
>gi|194018497 FYVE, RhoGEF and PH domain containing 5 [Homo sapiens]
Length = 1462
Score = 42.7 bits (99), Expect = 4e-04
Identities = 50/207 (24%), Positives = 82/207 (39%), Gaps = 31/207 (14%)
Query: 109 EAEPHTEPEEQVPVEAEPQNIEDEAKEQIQSLLHEMVHAEHVEGEDLQQEDGPTGEPQQE 168
E +E EE++ ++ED + + + H+ GED + D P GE +++
Sbjct: 158 EQVSRSEEEEKLVQPHRECSLEDSGPWAGEGVFQSDLLLPHIHGEDQEPPDTP-GEAEED 216
Query: 169 DDEFLMATDVDDRFETLEPEVSHE--------------ETEHSYHVEET-VSQDCNQDME 213
D+E +TD E P+ E E E V+E + DC + +E
Sbjct: 217 DEEGCASTDPAGADEGSGPDRPTEDMGQDAEDTSEEPPEKEELAGVQEAETATDCPEVLE 276
Query: 214 EMMSEQ------ENPDSSEPVVEDERLHHDTDDVTYQVY------EEQAVYEPLENEGIE 261
E E E D SEP +++ + + T + + EE P EN+ +E
Sbjct: 277 EGCEEATGVTGGEQVDLSEPPDHEKKTNQEVAAATLEDHAQDESAEESCQIVPFENDCME 336
Query: 262 --ITEVTAPP-EDNPVEDSQVIVEEVS 285
+T +T P E P E + E S
Sbjct: 337 DFVTSLTGSPYEFFPTESTSFCSESCS 363
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 42.4 bits (98), Expect = 5e-04
Identities = 45/180 (25%), Positives = 75/180 (41%), Gaps = 13/180 (7%)
Query: 121 PVEAEPQNIEDEAK---EQIQSLLHEMVHAEHVEGEDLQQEDGPTGEPQQEDDEFLMATD 177
P+E + EDE + E+ +S E E E ED +D + + DDE T
Sbjct: 1026 PLELDSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDE---DTA 1082
Query: 178 VDDRFETLEPEVSHEETEH--SYHVEETVSQDCNQDMEEMMSEQENPDSSEP----VVED 231
+ + E E + EET + E T S + ++ E S + +P SSE V +
Sbjct: 1083 LSEASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVARE 1142
Query: 232 ERLHHDTDDVTYQVYEEQAVYEPLENEGIEITEVT-APPEDNPVEDSQVIVEEVSIFPVE 290
E + +++ + A E E +G E AP D+ + +V +E ++ P E
Sbjct: 1143 EEEEEEEEEMVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEE 1202
Score = 32.7 bits (73), Expect = 0.40
Identities = 49/174 (28%), Positives = 67/174 (38%), Gaps = 29/174 (16%)
Query: 148 EHVEGEDLQQEDGPTGEPQ-QEDDEFLMATDVDDRFETLEPEVSHEET---------EHS 197
E E E L +E T E + E++E D DD + E E E+T E
Sbjct: 1034 EEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEGD 1093
Query: 198 YHVEETVSQDCNQDMEEMMSEQENPDSSEPVVEDERLHHDTDDVTYQVYEEQAVYEPLEN 257
EETVS ++ E S E+ +SSE E ++D V E+ E E
Sbjct: 1094 SDEEETVSIVTSK--AEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEE 1151
Query: 258 EGIEITEVTAPPED-------------NPVEDSQVIVEEVSIFPVEEQQEVPPD 298
E + +A PED P DS + EEV I E + V P+
Sbjct: 1152 MVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDI----ETEAVAPE 1201
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 42.0 bits (97), Expect = 7e-04
Identities = 34/154 (22%), Positives = 69/154 (44%), Gaps = 10/154 (6%)
Query: 77 DADGDGDFDVDDAKVLLGLKERSTSEPAVPPEEAEPHTEPEEQVPVEAEPQNIEDEAKEQ 136
D + D D D D+ ++ + + + PA E+ E + E+ + E + E+EA E
Sbjct: 156 DEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDD--DDEEDDSEEEAMET 213
Query: 137 IQSLLHEMVHAEHVEGEDLQQEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEETEH 196
+ + V+ +++ +++ + + EDD+ D DD + E + EE E
Sbjct: 214 TPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDD----DDEDDEDDDDEDDEEEEEEEE 269
Query: 197 SYHVEETVSQDCNQDMEEMMSEQENPDSSEPVVE 230
EE V + + +EM ++ P++ + VE
Sbjct: 270 ----EEPVKEAPGKRKKEMAKQKAAPEAKKQKVE 299
Score = 31.6 bits (70), Expect = 0.89
Identities = 37/178 (20%), Positives = 63/178 (35%), Gaps = 19/178 (10%)
Query: 94 GLKERSTSEPAVPPEEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQSLLHEMVHAEHVEGE 153
G K ++ EE + +E +E E EDE +++I+ + A
Sbjct: 133 GAKNGKNAKKEDSDEEEDDDSEEDE------EDDEDEDEDEDEIEPAAMKAAAA------ 180
Query: 154 DLQQEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEETEHSYHVEETVSQDCNQDME 213
P E + ++D+ D DD + E E + V E
Sbjct: 181 ------APASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAE 234
Query: 214 EMMSEQENPDSSEPVVEDERLHHDTDD-VTYQVYEEQAVYEPLENEGIEITEVTAPPE 270
+ E+++ D + ED+ D DD + EE+ V E E+ + A PE
Sbjct: 235 DEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPE 292
Score = 29.3 bits (64), Expect = 4.4
Identities = 18/66 (27%), Positives = 30/66 (45%)
Query: 213 EEMMSEQENPDSSEPVVEDERLHHDTDDVTYQVYEEQAVYEPLENEGIEITEVTAPPEDN 272
+E E+E+ DS E +DE D D++ + A E+E E E +D+
Sbjct: 142 KEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDD 201
Query: 273 PVEDSQ 278
+DS+
Sbjct: 202 EEDDSE 207
>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
sapiens]
Length = 1130
Score = 42.0 bits (97), Expect = 7e-04
Identities = 49/237 (20%), Positives = 87/237 (36%), Gaps = 22/237 (9%)
Query: 80 GDGDFDVDDAKVLLGLKERSTSEPAVPPEEAEPHTEPEEQVPVEAEPQNIED--EAKEQI 137
G G +++ ++ + E EE E E EE+ E E ++ E+ E +E+
Sbjct: 868 GGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEE 927
Query: 138 QSLLHEMVHAEHVEGEDLQQEDGPTGEPQQEDDEFLMATDVDDRFE-------TLEPEVS 190
+ E E E E+ ++E+ E + E+ E L E TL P +
Sbjct: 928 EEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALP 987
Query: 191 HEETEHSYHVEETVSQDCNQDMEEMMSEQENPDSSEPVVEDERLHHDTD----------- 239
E+ E ++EE +E+E + P + E L +
Sbjct: 988 PPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGESPAAG 1047
Query: 240 DVTYQVYEEQAVYEP--LENEGIEITEVTAPPEDNPVEDSQVIVEEVSIFPVEEQQE 294
++ EE+ P LE E + ++ PP + P E+ E +EQ +
Sbjct: 1048 PPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEMETETEAEALQEKEQDD 1104
Score = 36.6 bits (83), Expect = 0.028
Identities = 33/119 (27%), Positives = 48/119 (40%), Gaps = 7/119 (5%)
Query: 160 GPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEETEHSYHVEETVSQDCNQDMEEMMSEQ 219
G G P E+D L +++ E E E EE E EE ++ +D EE E+
Sbjct: 867 GGGGPPALEED--LTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEE 924
Query: 220 ENPD---SSEPVVEDERLHHDTDDVTYQVYEEQAVYEPLE--NEGIEITEVTAPPEDNP 273
E + E E+ L + ++ + EE E LE G E+ E PP P
Sbjct: 925 EEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLP 983
Score = 34.7 bits (78), Expect = 0.10
Identities = 38/162 (23%), Positives = 68/162 (41%), Gaps = 16/162 (9%)
Query: 81 DGDFDVDDAKVLLGLKERSTSEPAVPPEEAEPHTEPEEQ------VPVEAEPQNIEDEAK 134
D +F +V G T PA+PP E+ P +PE + + VE EP E+
Sbjct: 962 DLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVE-EPGTEEERGA 1020
Query: 135 EQIQSLLHEMVHAE-HVEGEDLQQEDGPTGEPQQEDD----EFLMATDVDDRFETLE--P 187
+ +L E + ++ VE E GP + E++ L+ + +D + ++ P
Sbjct: 1021 DTAPTLAPEALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPP 1080
Query: 188 EVSHEETEHSYHVEETVSQDCNQDMEEMMSEQEN--PDSSEP 227
E EE + E + + D M+++ + PD +P
Sbjct: 1081 ETPAEEEMETETEAEALQEKEQDDTAAMLADFIDCPPDDEKP 1122
>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
[Homo sapiens]
Length = 2073
Score = 42.0 bits (97), Expect = 7e-04
Identities = 48/201 (23%), Positives = 84/201 (41%), Gaps = 27/201 (13%)
Query: 98 RSTSEPAVPPEE---------AEPHTEPEEQVPVEAEPQNIEDEAKEQIQSLLHEMVHAE 148
+ T E +P EE P+T P E+ P + + E+E +E+ + E E
Sbjct: 1312 KETGEALLPQEENRREETCAPVSPNTSPGEK-PEDDLIKPEEEEEEEEEEEEEEEEEEGE 1370
Query: 149 HVEGEDLQQEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEETEHSYHVEE---TVS 205
EG ++D P G QE +E ++T+ +D + E EE E H E+
Sbjct: 1371 EEEGGGNVEKD-PDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDE 1429
Query: 206 QDCNQDMEEMMSEQENPDSSEPVVEDERLHHDTDDVTYQVYEEQAVYEPLENEGIEIT-- 263
D + + E+ E+ +S + V+E++ D + V + E L + G+++T
Sbjct: 1430 DDSHMESAEVEKEELPRESFKEVLENQETFLDLN-----VQPGHSNPEVLMDCGVDLTAS 1484
Query: 264 ------EVTAPPEDNPVEDSQ 278
E+ PE P D +
Sbjct: 1485 CNSEPKELAGDPEAVPESDEE 1505
Score = 32.3 bits (72), Expect = 0.52
Identities = 18/48 (37%), Positives = 25/48 (52%)
Query: 92 LLGLKERSTSEPAVPPEEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQS 139
LL L + S+ E +E E E EE+ E E + E+E +E IQS
Sbjct: 1061 LLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQS 1108
Score = 31.6 bits (70), Expect = 0.89
Identities = 28/130 (21%), Positives = 53/130 (40%), Gaps = 17/130 (13%)
Query: 96 KERSTSEPAVPPEEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQSLLHEMVHAEHVEGEDL 155
KE + AVP + EP + Q + + ++ E KE + + ++ E +
Sbjct: 1490 KELAGDPEAVPESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPATM-------EIDSETV 1542
Query: 156 QQEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEETEHSYHVEETVSQDCNQDMEEM 215
Q T E ++DD F + + +L+ ++ + S + T+ DC Q
Sbjct: 1543 QAVQSLTQESSEQDDTFQDCAETQEACRSLQ---NYTRADQSPQIATTL-DDCQQ----- 1593
Query: 216 MSEQENPDSS 225
S+ +P SS
Sbjct: 1594 -SDHSSPVSS 1602
Score = 30.4 bits (67), Expect = 2.0
Identities = 32/153 (20%), Positives = 53/153 (34%), Gaps = 22/153 (14%)
Query: 96 KERSTSEPAVPPEEAEPHTEPEEQVPVEAEPQNIEDEAKE--QIQSLLHEMVHAEHVEGE 153
+E E EE E E E VE +P + + KE +I + + + E E
Sbjct: 1352 EEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEE 1411
Query: 154 DLQQEDGPTGEPQQEDDE-------------------FLMATDVDDRFETLEPEVSHEET 194
+ + E+ E DDE F + + F L + H
Sbjct: 1412 EEEDEEPSHNEDHDADDEDDSHMESAEVEKEELPRESFKEVLENQETFLDLNVQPGHSNP 1471
Query: 195 EHSYHVEETVSQDCNQDMEEMMSEQEN-PDSSE 226
E ++ CN + +E+ + E P+S E
Sbjct: 1472 EVLMDCGVDLTASCNSEPKELAGDPEAVPESDE 1504
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 42.0 bits (97), Expect = 7e-04
Identities = 60/251 (23%), Positives = 102/251 (40%), Gaps = 41/251 (16%)
Query: 79 DGDGDFDVDDAKVLLGLKERSTSEPAVPPEEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQ 138
D +GD D K G KE E P +A E ++ E + + E +E+I+
Sbjct: 308 DNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIK 367
Query: 139 SLLHEMVHAEHVEGEDLQQEDGPTGEPQQEDDE--------------------------F 172
L E + A+ E E L+QE + ++++ +
Sbjct: 368 RL--EELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKL 425
Query: 173 LMATDVDDRFETLEPEVS--HEETEHSYHVEETVSQDCNQDME-----EMMSEQENPDSS 225
L A V+ + P+ +E+ + ++ S++ ++ ME E+M EQ P+
Sbjct: 426 LQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVM-EQGVPEKE 484
Query: 226 E--PVVEDERLHHDTDDVTYQVYEEQAVYEPLENEGIEITEVTAPPEDNPVEDSQVIVEE 283
E P VE E DT+D +E A E E E +E +V ++NP E+ + EE
Sbjct: 485 ETPPPVEPEE-EEDTEDAGLDDWEAMASDE--ETEKVEGNKVHIEVKENPEEEEEEEEEE 541
Query: 284 VSIFPVEEQQE 294
EE++E
Sbjct: 542 EEDEESEEEEE 552
Score = 38.5 bits (88), Expect = 0.007
Identities = 34/153 (22%), Positives = 62/153 (40%), Gaps = 21/153 (13%)
Query: 94 GLKERSTSEPAVPPEEAEPHTEP---------EEQVPVEAEPQNIEDEAKEQIQSLLHEM 144
G+ E+ + P V PEE E + ++ + E + E KE + E
Sbjct: 479 GVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEE 538
Query: 145 VHAEHVEGEDLQQEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEETEHSYHVEETV 204
E E + ++E+ E + D+E +D D +TL+ + S E +
Sbjct: 539 EEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKE-----------M 587
Query: 205 SQDCNQDMEEMMSEQENP-DSSEPVVEDERLHH 236
S D D ++ +++E D ++ +E RL H
Sbjct: 588 SSDSEYDSDDDRTKEERAYDKAKRRIEKRRLEH 620
Score = 28.1 bits (61), Expect = 9.8
Identities = 27/115 (23%), Positives = 43/115 (37%), Gaps = 8/115 (6%)
Query: 86 VDDAKVLLGLKERSTSEPAVPPEEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQSLLHEMV 145
V+ KV + +KE PEE E E EE+ E + E E++ E V
Sbjct: 518 VEGNKVHIEVKEN--------PEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKV 569
Query: 146 HAEHVEGEDLQQEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEETEHSYHV 200
E G+ L ++ E D T + ++ + + EHS +V
Sbjct: 570 SDEKDSGKTLDKKPSKEMSSDSEYDSDDDRTKEERAYDKAKRRIEKRRLEHSKNV 624
>gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens]
Length = 4374
Score = 40.8 bits (94), Expect = 0.001
Identities = 40/159 (25%), Positives = 60/159 (37%), Gaps = 4/159 (2%)
Query: 83 DFDVDDAKVLLGLKERSTSEPAVPPEEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQSLLH 142
D DV +V G +E +P +++ VE E +++ DE E+ +
Sbjct: 2305 DHDVTQTEVADGDIMDGEAETDSVVIAGQPEVLSSQEMQVENELEDLIDELLERDGGSGN 2364
Query: 143 EMVHAEHVEGEDLQQEDGPTGE-PQQEDDEFLMATDVDDRFETLEPEVSHEETEHSYHVE 201
+ GED QED E P + + +D L+PE E T+
Sbjct: 2365 STIIVSR-SGEDESQEDVLMDEAPSNLSQASTLQANREDSMNILDPEDEEEHTQEEDSSG 2423
Query: 202 ETVSQDCNQDMEEMMSEQENPDSSEPVVEDERLHHDTDD 240
+D +QD EE E E D + E E D DD
Sbjct: 2424 SNEDEDDSQDEEEEEEEDEEDDQEDD--EGEEGDEDDDD 2460
Score = 35.8 bits (81), Expect = 0.047
Identities = 31/126 (24%), Positives = 54/126 (42%), Gaps = 12/126 (9%)
Query: 115 EPEEQVPVEAEPQNIEDEAKEQIQSLLHEMVHAEHVEGEDLQQEDGPTGEPQQEDDEFLM 174
E +E V ++ P N+ + +Q+ + ++ E E+ E QE+D
Sbjct: 2376 ESQEDVLMDEAPSNLSQAST--LQANREDSMNILDPEDEE---------EHTQEEDSSGS 2424
Query: 175 ATDVDDRFETLEPEVSHEETEHSYHVEETVSQDCNQDMEEMMSEQENPD-SSEPVVEDER 233
D DD + E E EE + E +D + D EM +++ PD ++ P+V ER
Sbjct: 2425 NEDEDDSQDEEEEEEEDEEDDQEDDEGEEGDEDDDDDGSEMELDEDYPDMNASPLVRFER 2484
Query: 234 LHHDTD 239
+ D
Sbjct: 2485 FDREDD 2490
Score = 35.4 bits (80), Expect = 0.061
Identities = 21/82 (25%), Positives = 36/82 (43%), Gaps = 11/82 (13%)
Query: 98 RSTSEPAVPPEEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQSLLHEMVHAEHVEGEDLQQ 157
R S + PE+ E HT+ E+ + + +DE +E+ E E +D +
Sbjct: 2400 REDSMNILDPEDEEEHTQEEDSSGSNEDEDDSQDEEEEE-----------EEDEEDDQED 2448
Query: 158 EDGPTGEPQQEDDEFLMATDVD 179
++G G+ +DD M D D
Sbjct: 2449 DEGEEGDEDDDDDGSEMELDED 2470
>gi|7657138 golgi integral membrane protein 4 [Homo sapiens]
Length = 696
Score = 40.0 bits (92), Expect = 0.002
Identities = 41/183 (22%), Positives = 71/183 (38%), Gaps = 32/183 (17%)
Query: 115 EPEEQVPVEAEPQNIEDEAKEQIQSLLHEMVHAEHVEGEDLQQEDGPTGEPQQEDDEFLM 174
EP EQ P EA+P++ D A ED+ D P + + E +E
Sbjct: 525 EPREQGPREADPESEADRAAV-----------------EDINPADDPNNQGEDEFEEAEQ 567
Query: 175 ATDVDDRFETLEPEVSHEETEHSYHVEETVSQDCNQDMEEMMSEQENPDSSEPVVED--- 231
+ + E E + S+++ E++ E V E+ + EQ ++ E V ED
Sbjct: 568 VREENLPDENEEQKQSNQKQENTEVEEHLVMAGNPDQQEDNVDEQYQEEAEEEVQEDLTE 627
Query: 232 ---ERLHHDTDDVTYQVYEEQAVYEPLENEGIEITEVTAP--------PEDNPVEDSQVI 280
L H+ ++ TY +E + + E E+ + P E+ ED +
Sbjct: 628 EKKRELEHNAEE-TYGENDENTDDKNNDGEEQEVRDDNRPKGREEHYEEEEEEEEDGAAV 686
Query: 281 VEE 283
E+
Sbjct: 687 AEK 689
Score = 39.7 bits (91), Expect = 0.003
Identities = 38/148 (25%), Positives = 63/148 (42%), Gaps = 13/148 (8%)
Query: 97 ERSTSEPAVPPEEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQS-LLHEMVHAEH---VEG 152
+R+ E P ++ E E + + +N+ DE +EQ QS E E + G
Sbjct: 541 DRAAVEDINPADDPNNQGEDEFEEAEQVREENLPDENEEQKQSNQKQENTEVEEHLVMAG 600
Query: 153 EDLQQEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEETEHSYHVEETVSQDCNQDM 212
QQED + Q+E +E + +D E + E+ H E +Y + + D N D
Sbjct: 601 NPDQQEDNVDEQYQEEAEEEVQ----EDLTEEKKRELEH-NAEETYGENDENTDDKNNDG 655
Query: 213 EEMMSEQENPDSSEPVVEDERLHHDTDD 240
E EQE D + P +E + ++
Sbjct: 656 E----EQEVRDDNRPKGREEHYEEEEEE 679
Score = 33.1 bits (74), Expect = 0.31
Identities = 28/131 (21%), Positives = 52/131 (39%), Gaps = 1/131 (0%)
Query: 77 DADGDGDFDVDDAKVLLGLKERSTSEPAVPPEEAEPHTEPEEQVPVEAEPQNIEDEAKEQ 136
D + G+ + ++A+ + +E + + +TE EE + + P ED EQ
Sbjct: 553 DPNNQGEDEFEEAEQVREENLPDENEEQKQSNQKQENTEVEEHLVMAGNPDQQEDNVDEQ 612
Query: 137 IQSLLHEMVHAEHVEGEDLQQEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEETEH 196
Q E V + E E ++ + E E+DE + D + + + + E
Sbjct: 613 YQEEAEEEVQEDLTE-EKKRELEHNAEETYGENDENTDDKNNDGEEQEVRDDNRPKGREE 671
Query: 197 SYHVEETVSQD 207
Y EE +D
Sbjct: 672 HYEEEEEEEED 682
Score = 31.6 bits (70), Expect = 0.89
Identities = 35/165 (21%), Positives = 59/165 (35%), Gaps = 9/165 (5%)
Query: 96 KERSTSEPAVPPEEAEPHTEPEEQVPVEAEPQNIEDEAKEQIQSLLHEMVHAEHVEGEDL 155
KE P P ++ EPEE E + +E+E EQ+ H + EH +
Sbjct: 310 KEAEFQAPPEPIQQEVERREPEEHQVEEEHRKALEEEEMEQVGQAEH--LEEEHDPSPEE 367
Query: 156 QQEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEETEHSYHVEETVSQD--CNQDME 213
Q + Q+E L + + + +P + + EE + Q Q +E
Sbjct: 368 QDREWKEQHEQREAANLLEGHARAEVYPSAKPMIKFQSP-----YEEQLEQQRLAVQQVE 422
Query: 214 EMMSEQENPDSSEPVVEDERLHHDTDDVTYQVYEEQAVYEPLENE 258
E +E+ ++ L + QV E A+ E E
Sbjct: 423 EAQQLREHQEALHQQRLQGHLLRQQEQQQQQVAREMALQRQAELE 467
Score = 30.4 bits (67), Expect = 2.0
Identities = 34/140 (24%), Positives = 58/140 (41%), Gaps = 14/140 (10%)
Query: 110 AEPHTEPEEQVPVEAEPQNIEDEAKEQIQSLLHEMVHAEHVEGEDLQQEDGPTGEPQQED 169
A H E E Q P E Q +E E+ Q E H + +E E+++Q G+ + +
Sbjct: 306 APTHKEAEFQAPPEPIQQEVERREPEEHQV---EEEHRKALEEEEMEQ----VGQAEHLE 358
Query: 170 DEFLMATDVDDRFETLEPEVSHEETEHSYHVEETVSQDCNQDMEEMMSEQENPDSSEPVV 229
+E + + DR E + HE+ E + +E + + M+ Q E +
Sbjct: 359 EEHDPSPEEQDR----EWKEQHEQREAANLLEGHARAEVYPSAKPMIKFQ---SPYEEQL 411
Query: 230 EDERLHHDTDDVTYQVYEEQ 249
E +RL + Q+ E Q
Sbjct: 412 EQQRLAVQQVEEAQQLREHQ 431
>gi|122937247 unc-13 homolog A [Homo sapiens]
Length = 1791
Score = 40.0 bits (92), Expect = 0.002
Identities = 30/129 (23%), Positives = 55/129 (42%), Gaps = 7/129 (5%)
Query: 147 AEHVEGEDLQQEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEETEHSYHVE----E 202
+ + +L Q E D+ L +D++D + H SYH + +
Sbjct: 349 SRYASSGELSQGSSQLSEDFDPDEHSLQGSDMEDERDRDSYHSCHSSV--SYHKDSPRWD 406
Query: 203 TVSQDCNQDMEEMMSEQENPDSSEPVVEDERLHHDTDDVTYQVYEEQAVYEPLENEGIEI 262
++ +D+E+ + E+E P+ E + E+E D D +Y E+ AV EP + + I +
Sbjct: 407 QDEEELEEDLEDFLEEEELPEDEEELEEEEEEVPD-DLGSYAQREDVAVAEPKDFKRISL 465
Query: 263 TEVTAPPED 271
ED
Sbjct: 466 PPAAPGKED 474
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.307 0.129 0.367
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,371,205
Number of Sequences: 37866
Number of extensions: 676918
Number of successful extensions: 3925
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 95
Number of HSP's successfully gapped in prelim test: 327
Number of HSP's that attempted gapping in prelim test: 2800
Number of HSP's gapped (non-prelim): 1031
length of query: 299
length of database: 18,247,518
effective HSP length: 102
effective length of query: 197
effective length of database: 14,385,186
effective search space: 2833881642
effective search space used: 2833881642
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (22.0 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.