Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 145580615
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|145580615 KRI1 homolog [Homo sapiens]
(709 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|145580615 KRI1 homolog [Homo sapiens] 1444 0.0
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 74 6e-13
gi|148746195 trichohyalin [Homo sapiens] 71 4e-12
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 70 7e-12
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 69 1e-11
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 69 2e-11
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 67 6e-11
gi|13540523 nucleosomal binding protein 1 [Homo sapiens] 67 7e-11
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 66 1e-10
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 64 6e-10
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 61 4e-09
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 60 7e-09
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 60 7e-09
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 60 7e-09
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 58 3e-08
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 57 6e-08
gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens] 57 8e-08
gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens] 57 8e-08
gi|56676397 ankyrin repeat domain 11 [Homo sapiens] 56 1e-07
gi|15149465 caldesmon 1 isoform 5 [Homo sapiens] 56 1e-07
gi|4826657 caldesmon 1 isoform 2 [Homo sapiens] 56 1e-07
gi|31982906 cingulin-like 1 [Homo sapiens] 56 1e-07
gi|148839339 nexilin (F actin binding protein) [Homo sapiens] 56 1e-07
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 55 2e-07
gi|90819237 myeloid/lymphoid or mixed-lineage leukemia (trithora... 55 2e-07
gi|18375528 UPF3 regulator of nonsense transcripts homolog B iso... 55 2e-07
gi|22035604 mitogen-activated protein kinase kinase kinase kinas... 55 2e-07
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 55 3e-07
gi|148806928 hypothetical protein LOC57482 [Homo sapiens] 55 3e-07
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 55 3e-07
>gi|145580615 KRI1 homolog [Homo sapiens]
Length = 709
Score = 1444 bits (3737), Expect = 0.0
Identities = 709/709 (100%), Positives = 709/709 (100%)
Query: 1 MGHRTAMPEPRGSSQLRVNAAFAARYNRYREREELQRLKDRYGDRDSSSDSSSESDSSDE 60
MGHRTAMPEPRGSSQLRVNAAFAARYNRYREREELQRLKDRYGDRDSSSDSSSESDSSDE
Sbjct: 1 MGHRTAMPEPRGSSQLRVNAAFAARYNRYREREELQRLKDRYGDRDSSSDSSSESDSSDE 60
Query: 61 RVEFDPQQERDFYKTLSLLKKKDPRIYQKDATFYNRTASSSDSEEDPEALEKQKKVRPMY 120
RVEFDPQQERDFYKTLSLLKKKDPRIYQKDATFYNRTASSSDSEEDPEALEKQKKVRPMY
Sbjct: 61 RVEFDPQQERDFYKTLSLLKKKDPRIYQKDATFYNRTASSSDSEEDPEALEKQKKVRPMY 120
Query: 121 LKDYERKVILEKAGKYVDEENSDGETSNHRLQETSSQSYVEEQKQLKESFRAFVEDSEDE 180
LKDYERKVILEKAGKYVDEENSDGETSNHRLQETSSQSYVEEQKQLKESFRAFVEDSEDE
Sbjct: 121 LKDYERKVILEKAGKYVDEENSDGETSNHRLQETSSQSYVEEQKQLKESFRAFVEDSEDE 180
Query: 181 DGAGEGGSSLLQKRAKTRQEKAQEEADYIEWLKGQKEIRNPDSLKELTHLKEYWNDPELD 240
DGAGEGGSSLLQKRAKTRQEKAQEEADYIEWLKGQKEIRNPDSLKELTHLKEYWNDPELD
Sbjct: 181 DGAGEGGSSLLQKRAKTRQEKAQEEADYIEWLKGQKEIRNPDSLKELTHLKEYWNDPELD 240
Query: 241 EGERFLRDYILNKRYEEEEEEEEDEEEMEEEEGVHGPPVQLAVDDSSDEGELFLKKQEDF 300
EGERFLRDYILNKRYEEEEEEEEDEEEMEEEEGVHGPPVQLAVDDSSDEGELFLKKQEDF
Sbjct: 241 EGERFLRDYILNKRYEEEEEEEEDEEEMEEEEGVHGPPVQLAVDDSSDEGELFLKKQEDF 300
Query: 301 EQKYNFRFEEPDSASVKTYPRSIASSVRRKDERRKEKREETRERKKREKAKKQEELKQLK 360
EQKYNFRFEEPDSASVKTYPRSIASSVRRKDERRKEKREETRERKKREKAKKQEELKQLK
Sbjct: 301 EQKYNFRFEEPDSASVKTYPRSIASSVRRKDERRKEKREETRERKKREKAKKQEELKQLK 360
Query: 361 NLKRKEILAKLEKLRKVTGNEMLGLEEGDLEDDFDPAQHDQLMQKCFGDEYYGAVEEEKP 420
NLKRKEILAKLEKLRKVTGNEMLGLEEGDLEDDFDPAQHDQLMQKCFGDEYYGAVEEEKP
Sbjct: 361 NLKRKEILAKLEKLRKVTGNEMLGLEEGDLEDDFDPAQHDQLMQKCFGDEYYGAVEEEKP 420
Query: 421 QFEEEEGLEDDWNWDTWDGPEQEGDWSQQELHCEDPNFNMDADYDPSQPRKKKREAPLTG 480
QFEEEEGLEDDWNWDTWDGPEQEGDWSQQELHCEDPNFNMDADYDPSQPRKKKREAPLTG
Sbjct: 421 QFEEEEGLEDDWNWDTWDGPEQEGDWSQQELHCEDPNFNMDADYDPSQPRKKKREAPLTG 480
Query: 481 KKKRKSPFAAAVGQEKPVFEPGDKTFEEYLDEYYRLDYEDIIDDLPCRFKYRTVVPCDFG 540
KKKRKSPFAAAVGQEKPVFEPGDKTFEEYLDEYYRLDYEDIIDDLPCRFKYRTVVPCDFG
Sbjct: 481 KKKRKSPFAAAVGQEKPVFEPGDKTFEEYLDEYYRLDYEDIIDDLPCRFKYRTVVPCDFG 540
Query: 541 LSTEEILAADDKELNRWCSLKKTCMYRSEQEELRDKRAYSQKAQNSWKKRQVFKSLCREE 600
LSTEEILAADDKELNRWCSLKKTCMYRSEQEELRDKRAYSQKAQNSWKKRQVFKSLCREE
Sbjct: 541 LSTEEILAADDKELNRWCSLKKTCMYRSEQEELRDKRAYSQKAQNSWKKRQVFKSLCREE 600
Query: 601 AETPAEATGKPQRDEAGPQRQLPALDGSLMGPESPPAQEEEAPVSPHKKPAPQKRRRAKK 660
AETPAEATGKPQRDEAGPQRQLPALDGSLMGPESPPAQEEEAPVSPHKKPAPQKRRRAKK
Sbjct: 601 AETPAEATGKPQRDEAGPQRQLPALDGSLMGPESPPAQEEEAPVSPHKKPAPQKRRRAKK 660
Query: 661 ARLLGPTVMLGGCEFSRQRLQAFGLNPKRLHFRQLGRQRRKQQGPKNSS 709
ARLLGPTVMLGGCEFSRQRLQAFGLNPKRLHFRQLGRQRRKQQGPKNSS
Sbjct: 661 ARLLGPTVMLGGCEFSRQRLQAFGLNPKRLHFRQLGRQRRKQQGPKNSS 709
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 73.6 bits (179), Expect = 6e-13
Identities = 88/437 (20%), Positives = 194/437 (44%), Gaps = 49/437 (11%)
Query: 31 EREELQRLKDRYGDRDSSSDSSSESDSSDERVEFDPQQERDFYKTLSLLKKKDPRIYQKD 90
E+EE R ++ R E ++ + Q+ER ++ L++K+ R+ +++
Sbjct: 321 EQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEER-MWEQDERLREKEERMREQE 379
Query: 91 ATFYNRTASSSDSEEDPEALEKQKKVRPMY--LKDYERKVILEKAGKYVDEENSDGETSN 148
+ +E+ E++KK+R +++ E K+ ++ + EE E
Sbjct: 380 KMW----EQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEK---EWQQ 432
Query: 149 HRLQETSSQSYVEEQKQLKESFRAFVEDSEDEDGAGEGGSSLLQKRAKTRQEKAQEEADY 208
RL E + + +E+ Q +E + + ++ + D G Q++ RQEK +E+ D
Sbjct: 433 QRLPEQKEKLWEQEKMQEQEE-KIWEQEEKIRDQEEMWG----QEKKMWRQEKMREQEDQ 487
Query: 209 IEWLKGQKEIRNPDSLKELTHLKEYWN-DPELDEGERFLRDYILNKRYEEEEEEEEDEEE 267
+ W Q+E K + W D L E E +R+ K +++EE+ E+++
Sbjct: 488 M-W--EQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQ--KKMWQQEEKMREEKKT 542
Query: 268 MEEEEGVHGPPVQLAVDDSSDEGELFLKKQEDFEQKYNFRFEEPDSASVKTYPRSIASSV 327
E+E+ ++ ++ E E ++++E+ ++ + +E + +
Sbjct: 543 QEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQE------------EKM 590
Query: 328 RRKDER---RKEKREETRERKKREKAKKQEELKQLKNLKRKEILAKLEKLRKVTGNEMLG 384
R ++E+ ++EK +E E+ ++ K E+ ++ K +++E++ + E+ + +M
Sbjct: 591 REQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWE 650
Query: 385 LEEGDLEDDFDPAQHDQLMQKCFGDEYYGAVEEEKPQFEEEEGLEDD----------WNW 434
EE E + + ++ MQ G E +EEK Q +EE+ E + W
Sbjct: 651 QEEKMREQEEKMREQEEKMQ---GQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQ 707
Query: 435 DTWDGPEQEGDWSQQEL 451
+ ++E W Q+E+
Sbjct: 708 EEKMWGQEEKMWGQEEM 724
Score = 71.6 bits (174), Expect = 2e-12
Identities = 96/455 (21%), Positives = 195/455 (42%), Gaps = 41/455 (9%)
Query: 67 QQERDFYKTLSLLKKKDPRIYQKDATFYNRTASSSDSE----EDPEALEKQKKVRPMYLK 122
+QE ++ L++++ ++ +++ + + E E + L +QKK+R +
Sbjct: 252 KQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQ 311
Query: 123 DYERKVILEKAGKYVDEENSDGETSNHRLQETSSQSYVEEQKQLKESFRAFVEDS---ED 179
E++ + + + + E+ RL E Q +EQK + R + +D E
Sbjct: 312 MQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREK 371
Query: 180 EDGAGEGGSSLLQKRAKTRQEKAQEEADYIE---WLKGQKEIRNPDSLKELTHLKEYWND 236
E+ E Q++ ++EK QEE E ++ ++E K + W
Sbjct: 372 EERMRE------QEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQ 425
Query: 237 PELDEGERFLRDYILNKRYEEEEEEEEDEEEMEEEEGVHGPPVQLAVDDSSDEGELFLKK 296
E + ++ L + K +E+E+ +E++E+ E+EE + + E +++
Sbjct: 426 EEKEWQQQRLPEQ-KEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEK-MRE 483
Query: 297 QED--FEQKYNFRFEEPDSASVKTYPRSIASSVRRKDER-RKEKREETRERKKREKAKKQ 353
QED +EQ+ R +E + +R K+ER R++K+ +E K RE+ K Q
Sbjct: 484 QEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQ 543
Query: 354 EELK----QLKNLKRKEILAKLEKLRKVTGNEMLGLEEGDLEDDFDPAQHDQLMQKCFGD 409
E+ K Q + ++ +E + + EK + M EE E + + ++ M +
Sbjct: 544 EQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWE---- 599
Query: 410 EYYGAVEEEKPQFEEEEGLEDDWNWDTWDGPEQEGDWSQQELHCEDPNFNMDADYDPSQP 469
+EEK Q +EE+ E + W+ E++ Q+E+ E + + +
Sbjct: 600 ------QEEKMQEQEEKMWEQEEK--MWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQ 651
Query: 470 RKKKREAPLTGKKKRKSPFAAAVGQEKPVFEPGDK 504
+K RE ++K + GQE+ + E +K
Sbjct: 652 EEKMREQ----EEKMREQEEKMQGQEEKMREQEEK 682
Score = 54.7 bits (130), Expect = 3e-07
Identities = 60/332 (18%), Positives = 143/332 (43%), Gaps = 32/332 (9%)
Query: 31 EREELQRLKDRYGDRDSSSDSSSESDSSDERV---EFDPQQERDFYKTLSLLKKKDPRIY 87
E+E++Q +++ +++ E ++++ E +QE ++ ++ ++ +++
Sbjct: 444 EQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMW 503
Query: 88 QKDATFYNRTASSSDSEEDPEALEKQKKVRPMYLKDYERKVILEKAGKYVDEENSDGETS 147
++ + + + EE + +QKK+ K E K E+ K D+E E
Sbjct: 504 DQEERMWEQDERLREKEE---RMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEE 560
Query: 148 NHRLQETSSQSYVEEQKQLKESFRAFVEDSEDEDGAGEGGSSLLQKRAKTRQEKAQEEAD 207
R +E + E ++ +E + E +++ ++ ++EK QE+ +
Sbjct: 561 RMREREKKMREEEEMMREQEEKMQEQEEKMREQE-----------EKMWEQEEKMQEQEE 609
Query: 208 YIEWLKGQKEIRNPDSLKELTHLKEYWNDPELDEGERFLRDYILNKRYEEEEEEEEDEEE 267
+ W + +K + K + W E + + K +E+EE+ E EE+
Sbjct: 610 KM-WEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQE-------EKMWEQEEKMREQEEK 661
Query: 268 M-EEEEGVHGPPVQLAVDDSSDEGELFLKKQEDFEQKYNFRFEEPDSASVKTYPRSIA-- 324
M E+EE + G ++ + +G+ +K + E+K + E+ K + +
Sbjct: 662 MREQEEKMQGQEEKMREQEEKMQGQE--EKMREQEEKMRGQEEKMWGQEEKMWGQEEKMW 719
Query: 325 --SSVRRKDERRKEKREETRERKKREKAKKQE 354
+R K+ER ++++E+ +ER + + E
Sbjct: 720 GQEEMREKEERIRDQKEKMQERLPEHEERCSE 751
Score = 47.8 bits (112), Expect = 4e-05
Identities = 97/497 (19%), Positives = 203/497 (40%), Gaps = 64/497 (12%)
Query: 131 EKAGKYVDEENSDGETSNHRLQETS--SQSYVEEQKQLKESFR-AFVEDSEDEDGAGEGG 187
+KA +Y++E + + + L + ++ ++ +L+E R A E SE + E
Sbjct: 155 KKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELK 214
Query: 188 SSLLQKRAKTRQEKAQEEADYIEWLKGQKEIRNPDSLKELTHLKEYWNDPELDEGERFLR 247
L +RAK + Q E + ++E+R + K + + L E E +R
Sbjct: 215 RKL--ERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMR 272
Query: 248 DYILNKRYEEEEEEEEDEEEMEEEEGVHGPPVQLAVDDSSDEGELFLKKQEDFEQKYNFR 307
+ R +E+ E+++E E+E+ +L E E +++QE+ + +
Sbjct: 273 EQEEKMRRQEKRLREQEKELREQEK-------ELREQKKLREQEEQMQEQEEKMWEQEEK 325
Query: 308 FEEPDSASVKTYPRSIASSVRRKDERRKEKREETRERKKREKAKKQEE--LKQLKNLKRK 365
E + + R + +++ +K + +E R ++ E+ +++EE +Q K +++
Sbjct: 326 MREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQE 385
Query: 366 EILAKLEKLRKVTGNEMLGLEEGDLEDDFDPAQHDQLMQKCFGDEYYGAVEEEKPQFEEE 425
E + + E++R+ E+ E++ + ++ MQK +E+ +E+E
Sbjct: 386 EKMQEEERIRE--------REKKMREEEETMREQEEKMQK-----------QEENMWEQE 426
Query: 426 EGLEDDWNWDTWDGPEQ-EGDWSQQELHCEDPNFNMDADYDPSQPRKKKREAPLTGKKKR 484
E W PEQ E W Q+++ ++ Q K + + + G++K+
Sbjct: 427 EK-----EWQQQRLPEQKEKLWEQEKMQEQEEKI-------WEQEEKIRDQEEMWGQEKK 474
Query: 485 KSPFAAAVGQEKPVFEPGDKTFEEYLDEYYRLDYEDIIDDLPCRFKYRTVVPCDFGLSTE 544
QE ++E +K ++ E D E+ + + R + + E
Sbjct: 475 MWRQEKMREQEDQMWEQEEKMRDQ---EQKMWDQEERMWEQDERLREK-----------E 520
Query: 545 EILAADDKELNRWCSLKKTCMYRSEQEELRDKRAYSQKAQNSWKKRQVFKSLCREEAETP 604
E + K W +K + QE+ + +K + + R+ K + REE E
Sbjct: 521 ERMREQKK---MWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKM-REEEEMM 576
Query: 605 AEATGKPQRDEAGPQRQ 621
E K Q E + Q
Sbjct: 577 REQEEKMQEQEEKMREQ 593
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 70.9 bits (172), Expect = 4e-12
Identities = 127/666 (19%), Positives = 271/666 (40%), Gaps = 102/666 (15%)
Query: 15 QLRVNAAFAARYNRYREREELQRLK--DRYGDRDSSSDSSSE-------SDSSDERVEFD 65
Q R+ R + +REE++RL+ +R R + E S+ +ER +
Sbjct: 587 QQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQ 646
Query: 66 PQQERDFYKTLSLLKKKDP-RIYQKDATFYNRTASSSD--SEEDPEALEKQKKVRPMYLK 122
++E+ + L ++++ R+ Q+ + + EE +A E+ K P +
Sbjct: 647 LRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQW 706
Query: 123 DYERKVILEKAGKYVDEENSDGETSNHRLQETSSQSYVEEQKQLKESFRAFVEDSEDEDG 182
E + ++ Y +G+ R ++ + E + Q +E RA + E+E
Sbjct: 707 QLESEADARQSKVYSRPRKQEGQ--RRRQEQEEKRRRRESELQWQEEERAHRQQQEEE-- 762
Query: 183 AGEGGSSLLQKRAKTRQEKAQEEADYIEWLKGQKEIRNPDSLKELTHLKEYWNDPELDEG 242
Q+R T Q +A+E+++ +G++ + L+E ++ +
Sbjct: 763 ---------QRRDFTWQWQAEEKSE-----RGRQRLSARPPLREQRE-RQLRAEERQQRE 807
Query: 243 ERFL-----RDYILNKRYEEEEEEEEDEEEMEEEEGVHGPPVQLAVDDSSDEGELFLKKQ 297
+RFL ++ +R E E+E + EEE + + +Q D ++ E ++
Sbjct: 808 QRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQE 867
Query: 298 EDFEQKYNFRFEEPDSASVKT-YPRSIASSVRRKDERRKEKREETRERKKREKAKKQEEL 356
+ +QK+ ++ EE T Y + RK+++ ++ EE +R++REK ++QE+
Sbjct: 868 QRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQE 927
Query: 357 KQLKNLKRKEILAKLEKLRKVTGNEMLGLEEGDLEDDFDPAQHDQLMQKCFGDEYYGAVE 416
+Q + EE L+ + +QL+++ + +
Sbjct: 928 RQYR-------------------------EEEQLQQ-----EEEQLLRE---EREKRRRQ 954
Query: 417 EEKPQFEEEEGLEDDWNWDTWDGPEQEGDWSQQELHCEDPNFNMDADYDPSQPRKKKREA 476
E + Q+ +++ L+ + PE+ +++ + E+ + + + R+K+R
Sbjct: 955 ERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQ 1014
Query: 477 PLTGKKKRKSPFAAAVGQEKPVFEPGDKTFEEYLDEYYRLDYEDIIDDLPCRFKYRTVVP 536
+ ++K +E+ + E +K + + YR + E++ +
Sbjct: 1015 EWERQYRKKDELQQE--EEQLLREEREKRRLQERERQYR-EEEELQQE------------ 1059
Query: 537 CDFGLSTEEILAADDKELNRWCSLKKTCMYRSEQEELRDKRAYSQKAQNSWKKRQVFKSL 596
EE L +++E R L++ YR E EEL+ + + + ++RQ +
Sbjct: 1060 -------EEQLLGEERETRRRQELER--QYRKE-EELQQEEEQLLREEPEKRRRQERERQ 1109
Query: 597 CREEAETPAEATGKPQRDEAGPQRQLPALDGSLMGPESPPAQEEEAPVSPHKKPAPQKRR 656
CREE E E + + +RQ L+ E +EE+ + P+KRR
Sbjct: 1110 CREEEELQQEEEQLLREEREKRRRQ--ELERQYREEEEVQQEEEQL-----LREEPEKRR 1162
Query: 657 RAKKAR 662
R + R
Sbjct: 1163 RQELER 1168
Score = 70.5 bits (171), Expect = 5e-12
Identities = 121/658 (18%), Positives = 254/658 (38%), Gaps = 101/658 (15%)
Query: 11 RGSSQLRVNAAFAARYNRYREREELQRLKDRYGDRDSSSDSSSESDSSDERVEFDPQQER 70
R QLR RE++ + + R + + E + ++R++ + ++ R
Sbjct: 396 RREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERR 455
Query: 71 DFYKTLSLLKKKDPRIYQKDATFYNRTASSSDSEEDPEALEKQKKVRPMYLKDYERKVIL 130
D+ K +++ + + + D E++++ R + L++ ER+
Sbjct: 456 DWLKR------------EEETERHEQERRKQQLKRDQ---EEERRERWLKLEEEERREQQ 500
Query: 131 EKAGKYVDEENSDGETSNHRLQETSSQSYVEEQKQLKESFRAFVEDSEDEDGAGEGGSSL 190
E+ + + E E RL+ + ++++ + ++ R E+ ++ E L
Sbjct: 501 ERREQQLRREQE--ERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRL 558
Query: 191 LQKRAKTRQEKAQEEADYIEWLKGQKEIRNPDSLKELTHLKEYWNDPELDEGERFLRDYI 250
Q+R + R ++ QEE + L ++E R LK E E L +
Sbjct: 559 EQERREQRLKREQEERR--DQLLKREEERRQQRLKR--------------EQEERLEQRL 602
Query: 251 LNKRYEEEEEEEEDEEEMEEEEGVHGPPVQLAVDDSSDEGELFLKKQEDFEQKYNFRFEE 310
+ E E+EE E+ ++ EE QL + +E ++E E++ E
Sbjct: 603 KREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKRE 662
Query: 311 PDSASVKTYPRSIASSVRRKDERRKEKREETRERKKREKAKKQEELKQLKNLKRKEILAK 370
+ ++ + RR+ E +E++E+ RER K K Q +L+ + ++ ++ ++
Sbjct: 663 EEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSR 722
Query: 371 LEK----LRKVTGNEMLGLEEGDLEDDFDPAQHDQLMQKCFGDEYYGAVEEEKPQFEEEE 426
K R+ E E +L+ + H Q Q EEE+
Sbjct: 723 PRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQ-------------------QQEEEQ 763
Query: 427 GLEDDWNWDTWDGPEQEGDWSQQELHCEDPNFNMDADYDPSQPRKKKREAPLTGKKKRKS 486
+ W W E++ + +Q L P ++ R+++ + L +++++
Sbjct: 764 RRDFTWQWQA----EEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQ 819
Query: 487 PFAAAVGQEKPVFEPGDKTFEEYLDEYYRLDYEDIIDDLPCRFKYRTVVPCDFGLSTEEI 546
+EK + ++L+E +L + L EE
Sbjct: 820 RRRQRREREKEL---------QFLEEEEQLQRRERAQQ----------------LQEEED 854
Query: 547 LAADDKELNRWCSLKKTCMYRSEQEELRDKRAYSQKAQNSWKK--RQVFKSLCREEAETP 604
+D+E R ++ +R + EE R +R ++ A+ + ++ R+ + L EE E
Sbjct: 855 GLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQ 914
Query: 605 AEATGKPQRDEAGPQRQLPALDGSLMGPESPPAQEEEAPVSPHKKPAPQKRRRAKKAR 662
E K +R E Q + E Q+EE + ++ +KRRR ++ R
Sbjct: 915 REEREKRRRQEQERQYR-----------EEEQLQQEEEQLLREER---EKRRRQERER 958
Score = 66.2 bits (160), Expect = 1e-10
Identities = 124/681 (18%), Positives = 270/681 (39%), Gaps = 62/681 (9%)
Query: 15 QLRVNAAFAARYNRYREREELQRLKD-----RYGDRDSSSDSSSESDSSDERVEFDPQQE 69
QLR R R E ++ QRL+ R + + + + R + + ++E
Sbjct: 277 QLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERRE 336
Query: 70 RDFYKTLSLLKKKDPRIYQKDATFYNRTASSSDSEEDPEALEKQKKVRPMYL-------- 121
+ + +++ R Q++ + + E + L +++++R
Sbjct: 337 QQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLR 396
Query: 122 --KDYERKVILEKAGKYVDEENSDGETSNHRLQETSSQSYVEEQKQLKESFRAFVEDSED 179
+ R+ L + + E+ E R QE EQ++ ++ + E+ D
Sbjct: 397 REQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRD 456
Query: 180 EDGAGEGGSSLLQKRAKTRQEKAQEEADYIEWLKGQKEIRNPDSLKELTHLKEYWNDPEL 239
E Q+R K + ++ QEE WLK ++E R + L+ +
Sbjct: 457 WLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERRE 516
Query: 240 DEGERFLRDYILNKRYEEEE----EEEEDEEEM---EEEEGVHGPPVQLAVDDSSDEGEL 292
+R + L +R E+ E+EE E++ EEE+ + + + +E
Sbjct: 517 QRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRD 576
Query: 293 FLKKQEDFEQKYNFRFEEPDSASVKTYPRSIASSVRRKDERRKEKREETRERKKRE--KA 350
L K+E+ ++ + E+ + + + + + ++ KREE E ++++ K+
Sbjct: 577 QLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKS 636
Query: 351 KKQEELKQLKNLKRKEILAKLEKLRKVTGNEMLGLEEGDLEDDFDPAQHDQLMQKCFGDE 410
++QEE +Q + L+R++ + ++L++ E L E L+ + + + +Q +
Sbjct: 637 EEQEERRQ-QQLRREQQERREQRLKREEEEERL---EQRLKREHEEERREQEL------- 685
Query: 411 YYGAVEEEKPQFEEEEGLEDDWNWDTWDGPEQEGDWSQQELHCEDPNFNMDADYDPSQPR 470
A EE++ E + W W E E D Q +++ + +
Sbjct: 686 ---AEEEQEQARERIKSRIPKWQWQL----ESEADARQSKVYSRPRKQEGQRRRQEQEEK 738
Query: 471 KKKREAPLTGKKKRKSPFAAAVGQEKPVFEPGDKTFEEYLDEYYRLDYEDIIDDLPCRFK 530
+++RE+ L +++ + A Q++ + D T++ +E + + P R +
Sbjct: 739 RRRRESELQWQEEER-----AHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQ 793
Query: 531 YRTVVPCDFGLSTEEILAADDKE----LNRWCSLKKTCMYRSEQEELRDKRAYSQKAQNS 586
+ + E+ +++E + +K + E+E+L+ +R +Q+ Q
Sbjct: 794 RERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQ-RRERAQQLQEE 852
Query: 587 WKKRQVFKSLCREEAETPAEATGKPQRDEAGPQRQ-----LPALDGSLMGPESPPAQEEE 641
Q + R E + + Q +E +R+ PAL L E QEEE
Sbjct: 853 EDGLQEDQER-RRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLR-KEQQLLQEEE 910
Query: 642 APVSPHKKPAPQKRRRAKKAR 662
+ ++ +KRRR ++ R
Sbjct: 911 EELQREER---EKRRRQEQER 928
Score = 66.2 bits (160), Expect = 1e-10
Identities = 116/531 (21%), Positives = 222/531 (41%), Gaps = 80/531 (15%)
Query: 30 REREELQRLKDRYGDRDSSSDSSSESDSSDERVEFDP-----QQERDFYKTLSLLK--KK 82
+EREE Q L+ + DR + + + +E + ++ER F K L+ ++
Sbjct: 1346 QEREE-QPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQER 1404
Query: 83 DPRIYQ-KDATFYNRTASSSDSEEDPEALEKQKKVRPMYLK----DYERKVILEKAGKYV 137
+ ++ Q +D F S E D + E++++VR + + E+++ E+ K+
Sbjct: 1405 EQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFR 1464
Query: 138 DEENSDGETSNHRL-QETSSQSYVEEQKQLK--ESFRAFVEDS-EDEDGAGEGGSSLLQK 193
+EE E +L ++ + ++EE++QL+ E R F E ++ + Q
Sbjct: 1465 EEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQL 1524
Query: 194 RAKTRQEK-AQEEADYIEWLKGQKEIRNPD-SLKELTHLKEYWNDPELDEGER---FLRD 248
+ RQ K QEE +GQ+ ++ D +E L++ + +L ER F +
Sbjct: 1525 HRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLE 1584
Query: 249 YILNKRYEEEEEEEEDEEEMEEEEGVHGPPVQLAVDDSSDEGELFLKKQEDF-----EQK 303
+R E+E + EDE+++ +EG ++ D E E L+++E+ E+
Sbjct: 1585 EQKVRRQEQERKFMEDEQQLRRQEGQQ--QLRQERDRKFREDEQLLQEREEQQLHRQERD 1642
Query: 304 YNFRFEEPD------------------SASVKTYPRSIASSVRRKDERRKEKREET---- 341
F EEP + +RR++ RK + EE
Sbjct: 1643 RKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRR 1702
Query: 342 --RERK---------KREKAKKQEELKQLKNLKRKEILAKLEKLRKVTGNEMLGLEEGD- 389
RERK ++E +K E +QL+ +E L + E+ RK+ E L E +
Sbjct: 1703 QERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQ 1762
Query: 390 ----LEDDFDPAQHDQLMQKCFGDEYYGAVEEEKPQFEEEEGLEDDWNWDTWDGPEQEGD 445
E D + +QL Q+ +E +E +F EEE L + +++G
Sbjct: 1763 QLRRQERDRKFREEEQLRQE--REEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGK 1820
Query: 446 --WSQQELHCEDPNFNMDADYD---------PSQPRKKKREAPLTGKKKRK 485
W +++L E+ + + D +Q + ++ E L ++++K
Sbjct: 1821 YRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQK 1871
Score = 65.9 bits (159), Expect = 1e-10
Identities = 82/408 (20%), Positives = 169/408 (41%), Gaps = 32/408 (7%)
Query: 25 RYNRYREREELQRLK--DRYGDRDSSSDSSSESDSSDERVEFDPQQERDFYKTLSLLKKK 82
R +YRE EELQR K RY D D SD + + E D + + + +
Sbjct: 1195 RERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLE 1254
Query: 83 DPRIYQKDATFYNRTASSSDSEEDPEALEKQKKVRPMYLKDYERKVILEKAGKYVDEENS 142
D ++ + + + E D E ++ + R + + E+ LE+ EE
Sbjct: 1255 DSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQ---LER------EEQK 1305
Query: 143 DGETSNHRLQETSS--QSYVEEQKQLKESFRAFVEDSEDEDGAGEGGSSLLQKRAKTRQE 200
+ + + + QE + EE+++ +E+ R F E+ + E ++ K R+E
Sbjct: 1306 EAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREE 1365
Query: 201 KAQEEADYIEWLKGQKEIRNPDSLKELTHLKEYWNDPELDEGERFLRDYILNKRYEEEEE 260
+ + + ++L+ ++ +R + ++ ++ E ++ R RD + ++
Sbjct: 1366 ELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSR 1425
Query: 261 EEEDEEEMEEEEGVHGPPVQLAVDDSSDEGELFLKKQEDFEQKYNFRFEEPDSASVKTYP 320
+E D + EEE+ V + FL++++ Q+ + +F E + +
Sbjct: 1426 QERDRKFREEEQQVR----------RQERERKFLEEEQQLRQERHRKFREEEQLLQEREE 1475
Query: 321 RSIASSVRRKD--ERRKEKREETRERKKREKAKKQEELKQLKNLKRKEILAKLEKLRKVT 378
+ + R + E ++ R + R+RK RE+ + +E + K L+ ++ L + ++ RK
Sbjct: 1476 QQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQE-PERKFLEEEQQLHRQQRQRKFL 1534
Query: 379 GNEMLGLEEGDLEDDFDPAQHDQLMQKCFGDEYYGAVEEEKPQFEEEE 426
EE L Q Q + F +E E E+ Q +E
Sbjct: 1535 ------QEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQE 1576
Score = 65.5 bits (158), Expect = 2e-10
Identities = 110/605 (18%), Positives = 249/605 (41%), Gaps = 74/605 (12%)
Query: 30 REREELQRLKDRYGDRDSSSDSSSESDSSDERVEFDPQQERDFYKTLSLLKKKDPRIYQK 89
R+ E+ +R + R D E + R + +QER+ + +K++ R+ Q+
Sbjct: 114 RQEEDQRRFEPR--------DRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQE-RLEQR 164
Query: 90 DATFYNRTASSSDSEEDPEALEKQKKVRPMYLKDYERKVILEKAGKYVDEENSDGETSNH 149
D D E ++++ + + E + + G +E + +
Sbjct: 165 DR-----------QRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRR 213
Query: 150 RLQETSSQSYVEEQKQLKE-SFRAFVEDSEDEDGAGEG----GSSLLQKRAKTRQEKAQE 204
L E + E+Q+Q +E R F E+ E E E LQ+ RQ + QE
Sbjct: 214 ELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQE 273
Query: 205 EADYIEWLKGQKEIRNPDSLKELTHLKEYWNDPELDEGERFLRDYILNKRYEEEEEEEED 264
E + + L+ Q+ R E + +R R+ L ++ EEE E+++
Sbjct: 274 EEEQLRKLERQELRRE--------------RQEEEQQQQRLRREQQLRRKQEEERREQQE 319
Query: 265 EEEMEEEEGVHGPPVQLAVDDSSDEGELFLKKQEDFEQKYNFRFEEPDSASVKTYPRSIA 324
E ++E + + E L+++++ ++ R E+ + + R
Sbjct: 320 ERREQQERR----------EQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQE 369
Query: 325 SSVRRKDERRKEKREETRERKKREKAKKQEELKQLKNLKRKEILAKLEKLRKVTGNEMLG 384
R + RR+++ ++ ++ ++ +++++L++ + L+R++ L + ++LR+
Sbjct: 370 EERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRR-------- 421
Query: 385 LEEGDLEDDFDPAQHDQLMQKCFGDEYYGAVEEEKPQF---EEEEGLEDDWNWDTWDGPE 441
E L + + +H+Q ++ ++ +EE+ + EEE + +
Sbjct: 422 --EQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRD 479
Query: 442 QEGDWSQQELHCEDPNFNMDADYDPSQPRKKKREAPLTGKKKRKSP--FAAAVGQEKPVF 499
QE + ++ L E+ + Q R+++ E K+++ + E+ +
Sbjct: 480 QEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLR 539
Query: 500 EPGDKTFEEYL--DEYYRLDYEDIIDDLPCRFKYR--TVVPCDFGLSTEEILAADDKELN 555
++ E+ L +E RL+ E L + R ++ + + + ++ L
Sbjct: 540 REQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLE 599
Query: 556 RWCSLKKTCMYRSEQEELRDKRAYSQKAQNSWKKRQVFKSLCREEAETPAEATGKPQRDE 615
+ LK+ + R EQEE R++R ++ + +++Q+ KS EE E + + ++ E
Sbjct: 600 Q--RLKREEVERLEQEERREQRLKREEPEEE-RRQQLLKS---EEQEERRQQQLRREQQE 653
Query: 616 AGPQR 620
QR
Sbjct: 654 RREQR 658
Score = 62.8 bits (151), Expect = 1e-09
Identities = 104/494 (21%), Positives = 195/494 (39%), Gaps = 77/494 (15%)
Query: 25 RYNRYREREELQRLKDRYGDRDSSSDSSSESDSSDERVEFDPQQERDFYKTLSLLKKKDP 84
R +YRE EELQ+ +++ + E + + + Q+E L ++++
Sbjct: 986 REKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQL-----LREEREK 1040
Query: 85 RIYQKDATFYNRTASSSDSEEDPEALEKQKKVRPMYLKDYERKVILEKAGKYVDEENSDG 144
R Q+ Y EE E++ + R + Y ++ L++ + + E
Sbjct: 1041 RRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLRE---- 1096
Query: 145 ETSNHRLQETSSQSYVEEQKQLKESFRAFVEDSEDEDGAGEGGSSLLQKRAKTRQEKAQE 204
E R QE Q EE+ Q +E + + ++ E L+++ + +E QE
Sbjct: 1097 EPEKRRRQERERQCREEEELQQEEE--QLLREEREKRRRQE-----LERQYREEEEVQQE 1149
Query: 205 EADYIEWLKGQKEIRNPDSLKELTHLKEYWNDPELDEGERFLRDYILNKRYEEEEEEEED 264
E + L+ + E R L+ ++Y + EL + E L KR +E E + +
Sbjct: 1150 EE---QLLREEPEKRRRQELE-----RQYREEEELQQEEEQLLREEQEKRRQERERQYRE 1201
Query: 265 EEEMEEEEGVH---------------GPPVQLAVDDSSDEGELFLK--KQEDFEQKYNFR 307
EEE++ ++ P + AV D+ +++ K + E F Q + +
Sbjct: 1202 EEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDN----KVYCKGRENEQFRQLEDSQ 1257
Query: 308 FEEPDSASVKTYPRSIASSVRRKDERRK-------------EKREETRERKKREKAKKQE 354
+ S + R+ ERR+ +REE +E K+R+ +K +
Sbjct: 1258 LRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRD--RKSQ 1315
Query: 355 ELKQLKNLKRKEILAKLEKLRKVTGNEMLGLEEGDLEDDFDPAQHDQLMQKCFGDEYYGA 414
E KQL +R+E + E RK E L L++ + Q + F +E
Sbjct: 1316 EEKQLLREEREEKRRRQETDRKFREEEQL------LQEREEQPLRRQERDRKFREEELRH 1369
Query: 415 VEEEKPQFEEEEGLEDDWNWDTWDGPEQEGDWSQQELHCEDPNFNMDADYDPSQPRKKKR 474
E+ + EEE+ L E++ +Q+L C++ + D D RK +
Sbjct: 1370 QEQGRKFLEEEQRLRRQER-------ERKFLKEEQQLRCQEREQQLRQDRD----RKFRE 1418
Query: 475 EAPLTGKKKRKSPF 488
E +++R F
Sbjct: 1419 EEQQLSRQERDRKF 1432
Score = 57.8 bits (138), Expect = 3e-08
Identities = 82/420 (19%), Positives = 184/420 (43%), Gaps = 53/420 (12%)
Query: 25 RYNRYREREEL------QRLKDRYGDRDSSSDSSSESDSSDERVEFDPQQERDFYKTLSL 78
R ++RE E+L Q+L + DR + ER + +Q+ +
Sbjct: 1553 RDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQ 1612
Query: 79 LKKKDPRIYQKDATFYNRTASSS--DSEEDPEALEKQKKVRPMYLKDYERKVILEKAGKY 136
L+++ R +++D E D + LE++ ++R ++ E+++ ++ K+
Sbjct: 1613 LRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRR---QEREQQLRHDRDRKF 1669
Query: 137 VDEEN--SDGETSNHRLQETSSQSYVEEQKQLK--ESFRAFVEDSEDEDGAGEGGSSLLQ 192
+EE +GE R QE + + EE++QL+ E R F+++ + Q
Sbjct: 1670 REEEQLLQEGEEQQLRRQERD-RKFREEEQQLRRQERERKFLQEEQ-------------Q 1715
Query: 193 KRAKTRQEKAQEEADYIEWLKGQKEIRNPDSLKELTHLKEYWNDPELDEGERFLRDYILN 252
R + + K +EE + + Q+++R + +++ L+E PE +E + LR +
Sbjct: 1716 LRRQELERKFREE-EQLRQETEQEQLRRQERYRKI--LEEEQLRPEREEQQ--LRRQERD 1770
Query: 253 KRYEEEEE--EEEDEEEMEEEEGVHGPPVQLAVDDSSDEGELFLKKQEDFEQKYNFRFEE 310
+++ EEE+ +E +E+++ +E + + +E +L + + + KY + E+
Sbjct: 1771 RKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQL---RPQQRDGKYRWEEEQ 1827
Query: 311 PDSASVKTYPRSIASSVRRKDERRKEKREETRERKKREKAKKQEELKQLKNLKRKEILAK 370
+ R R + R E++ T+E+ +RE+ + +E +Q + +R+ L +
Sbjct: 1828 LQLEEQEQRLRQ-----ERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLRE 1882
Query: 371 LEKLRKVTGNEMLGLEEGDLEDD--------FDPAQHDQLMQKCFGDEYYGAVEEEKPQF 422
E +R+ E + G+++ +P H Y ++E++ Q+
Sbjct: 1883 -EHIRRQQKEEQRHRQVGEIKSQEGKGHGRLLEPGTHQFASVPVRSSPLYEYIQEQRSQY 1941
Score = 54.7 bits (130), Expect = 3e-07
Identities = 63/258 (24%), Positives = 118/258 (45%), Gaps = 26/258 (10%)
Query: 178 EDEDGAGEGGSSLLQKRAKTRQEKAQEEAD-YIEWLKGQKEI-RNPDSLKELTHLKEYWN 235
E++ +G SLLQ R + ++ E D +E GQ+ + + +EL +E
Sbjct: 97 EEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSE 156
Query: 236 DPE-LDEGERFLRDYILNKRYEEEEEEEEDEEEMEEEEGVHGPPVQLAVDDSSDEGELFL 294
E L++ +R RD L ++ +E +E EE E E+ + G + D+ L
Sbjct: 157 KQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQ------L 210
Query: 295 KKQEDFEQKYNFRFEEPDSASVKTYPRSIASSVRRKDERRKEKREETRERKKREKA--KK 352
+++E E + R E+ RR+ + R + EE +E +KRE K+
Sbjct: 211 RRRELLELRRKGREEKQQQ--------------RRERQDRVFQEEEEKEWRKRETVLRKE 256
Query: 353 QEELKQLKNLKRKEILAKLEKLRKVTGNEMLGLEEGDLEDDFDPAQHDQLMQKCFGDEYY 412
+E+L++ + +++E+ + E+LRK+ E L E + E + +Q +++ +E
Sbjct: 257 EEKLQEEEPQRQRELQEEEEQLRKLERQE-LRRERQEEEQQQQRLRREQQLRRKQEEERR 315
Query: 413 GAVEEEKPQFEEEEGLED 430
EE + Q E E E+
Sbjct: 316 EQQEERREQQERREQQEE 333
Score = 45.8 bits (107), Expect = 1e-04
Identities = 48/229 (20%), Positives = 103/229 (44%), Gaps = 18/229 (7%)
Query: 144 GETSNHRLQETSSQSYVEEQKQLKESFRAFVEDSEDEDGAGEGGSSLLQKRAKTRQEKAQ 203
G R + +S +++++Q ++ R D + E+ G Q+R + RQE+ +
Sbjct: 94 GLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPG-------QRRRQKRQEQER 146
Query: 204 EEADYIEWLKGQKEIRNPDSLK---ELTHLKEYWNDPELDEGERFLRDYILNKRYEEEEE 260
E A+ E + Q+ + D + EL ++ W + E ER + L E E
Sbjct: 147 ELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQERE----ERRAEEEQLQSCKGHETE 202
Query: 261 EEEDEEEMEEEEGVH---GPPVQLAVDDSSDEGELFLKKQEDFEQKYNFRFEEPDSASVK 317
E DEE++ E + + + +F +++E +K + + +
Sbjct: 203 EFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQE 262
Query: 318 TYPRSIASSVRRKDERRKEKREETRERKKREKAKKQEELKQLKNLKRKE 366
P+ +++ RK +R+E R R+++E+ ++Q+ L++ + L+RK+
Sbjct: 263 EEPQRQRELQEEEEQLRKLERQELR-RERQEEEQQQQRLRREQQLRRKQ 310
Score = 33.1 bits (74), Expect = 0.91
Identities = 31/126 (24%), Positives = 59/126 (46%), Gaps = 11/126 (8%)
Query: 540 GLSTEEILAADDKELNRWCSLKKTCMYRSEQEEL---RDKRAYSQKAQNSWKKRQVFKSL 596
G TEE D+++L R L+ R E+++ R R + ++ + W+KR+ ++
Sbjct: 198 GHETEEF--PDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRE---TV 252
Query: 597 CREEAETPAEATGKPQRDEAGPQRQLPALDGSLMGPESPPAQEEEAPVSPHKKPAPQKRR 656
R+E E E + QR+ + QL L+ + E QEEE ++ +R+
Sbjct: 253 LRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRE---RQEEEQQQQRLRREQQLRRK 309
Query: 657 RAKKAR 662
+ ++ R
Sbjct: 310 QEEERR 315
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 70.1 bits (170), Expect = 7e-12
Identities = 93/488 (19%), Positives = 210/488 (43%), Gaps = 58/488 (11%)
Query: 30 REREELQRLKDRYGDRDSSSDSSSESDSSDERVEFDPQQERDFYKTLSLLKKKDPRIYQK 89
R RE+ + L+++ + + + + E+ E +QE + + +++ R++++
Sbjct: 322 RLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQ 381
Query: 90 DATFYNRTASSSDSEEDPEALEKQKKVRPMYLKDYERKVILEKAGKYVDEENSDGETSNH 149
+ + D EE E+ +++R + E++ + E+ K +E+ +
Sbjct: 382 EKQMREQEQKMRDQEE--RMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKT 439
Query: 150 RLQETSSQSYVEEQKQLKESFRAFVEDSEDEDGAGEGGSSLLQKRAKTRQEKAQEEADYI 209
R QE Q E+++++E + E+ E + Q+ +QE+ E +
Sbjct: 440 RDQEEKMQ----EEERIREREKKMREEEE---------TMREQEEKMQKQEENMWEQEEK 486
Query: 210 EWLKGQKEIRNPDSLKELTHLKEYWNDPELDEGERFLRDYILNKRYEEEEEEEEDEEEME 269
EW ++ R P+ ++L W ++ E E K +E+EE+ + EE
Sbjct: 487 EW----QQQRLPEQKEKL------WEQEKMQEQE--------EKIWEQEEKIRDQEEMWG 528
Query: 270 EEEGVHGPPVQLAVDDSSDEGELFLKKQE----DFEQKYNFRFEEPDSASVKTYPR--SI 323
+E+ + +D E E ++ QE D E++ + +E + KT+ + +
Sbjct: 529 QEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEK---KTWDQEEKM 585
Query: 324 ASSVRRKDERRKEKREETRERKKREKAKKQEELKQLKNLK---RKEILAKLEKLRKVTGN 380
R ++ +K + EE R++ EK ++QEE Q + K ++E + + E+
Sbjct: 586 REEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEE 645
Query: 381 EMLGLEEGDLEDDFDPAQHDQLMQKCFGDEYYGAVEEEKPQFEEEEGLEDDWNWDTWDGP 440
+M EE E P Q ++L E+ E+EK Q E+EE + + +
Sbjct: 646 KMWEQEEKMWEQQRLPEQKEKLW------EHEKMQEQEKMQ-EQEEKIWEQEKMEKKTQE 698
Query: 441 EQEGDWSQQELHCEDPNFNMDADYDPSQPRKKKREAPLTGKKKRKSPFAAAVGQEKPVFE 500
+++ W Q+++ E+ + + +++E + ++++ QE+ ++E
Sbjct: 699 QEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQE------QEEEMWE 752
Query: 501 PGDKTFEE 508
+K +E+
Sbjct: 753 QEEKMWEQ 760
Score = 68.6 bits (166), Expect = 2e-11
Identities = 88/478 (18%), Positives = 214/478 (44%), Gaps = 42/478 (8%)
Query: 28 RYREREELQRLKDRYGDRDSSSDSSSESDSSDERVEFDPQQERDFYKTLSLLKKKDPRIY 87
R RERE+ R ++ R+ + ++ E+ E + QQ+R + L +++ ++
Sbjct: 451 RIREREKKMR-EEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQE--KMQ 507
Query: 88 QKDATFYNRTASSSDSEE---DPEALEKQKKVRPM--YLKDYERKVILEKAGKYVDEENS 142
+++ + + D EE + + +Q+K+R + + E K+ ++ + EE
Sbjct: 508 EQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERM 567
Query: 143 DGETSNHRLQETSSQSYVEEQKQLKESFRAFVEDSEDEDGAGEGGSSLLQKRAKTRQEKA 202
+ +T + + + E+++++E + E+ E E +Q++ + QE+
Sbjct: 568 EKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEK----MQEQEEKMQEQE 623
Query: 203 QEEADYIEWLKGQKEIRNPDSLKELTHLKEYWNDPELDEGERFLRDYILNKRYEEEEEEE 262
++ + E ++ Q+E K ++ W L E + L ++ ++ +E+E+ +
Sbjct: 624 EKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEH---EKMQEQEKMQ 680
Query: 263 EDEEEMEEEEGVHGPPVQLAVDDSSDEGELFLKKQEDFEQKYNFRFEEPDSASVKTYPRS 322
E EE++ E+E ++ + E E QE ++ + R E + R
Sbjct: 681 EQEEKIWEQE---------KMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMRE 731
Query: 323 IASSVRRKDERRKEKREETRERKKREKAKKQEELKQLKNLKRKEILAKLEKLRKVTGNEM 382
++ ++E+ +E+ EE E++++ ++++ +Q + ++KE L + EK+++ E
Sbjct: 732 QEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQE---QEK 788
Query: 383 LGLEEGDLEDDFDPAQHDQLMQKCFGDEYYGAVEEEKPQFEEEEGLEDDWNWDTWDGPEQ 442
+ +E + D + + + +K G E +EEK +EE+ W + ++
Sbjct: 789 IWEQEEKMRDQEEKMRGQE--EKMRGQEEKMRGQEEKMWGQEEK----MWGQEEKMWGQE 842
Query: 443 EGDWSQQELHCEDPNFNMDADYDPSQPRKKKREAPLTG-KKKRKSPFAAAVGQEKPVF 499
E W Q+E M+ + + +++E + G ++K + GQE+ ++
Sbjct: 843 EKMWGQEE--------KMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEEKIY 892
Score = 60.8 bits (146), Expect = 4e-09
Identities = 98/476 (20%), Positives = 201/476 (42%), Gaps = 65/476 (13%)
Query: 192 QKRAKTRQEKAQEEADYIEWLKGQKEIRNPDSLKELTHLKEYWNDPELDEGERFLRDYIL 251
+K+ + ++EK + + + +G+ + ++ L+E + EL E E+ LR+
Sbjct: 285 EKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLRE--QEKELREQEKELREQ-K 341
Query: 252 NKRYEEEEEEEEDEEEMEEEEGVHGPPVQLAVDDSSDEGELFLKKQEDFEQKYNFRFEEP 311
R +EE+ +E++E+ E+EE + E +++ +++ +EQ+ R +E
Sbjct: 342 ELREQEEQMQEQEEKMWEQEEKMR-----------EQEEKMWRQEERLWEQEKQMREQEQ 390
Query: 312 DSASVKTYPRSIASSVRRKDERRKEKREETRERKKR-EKAKKQEELKQLKNLKRKEILAK 370
R + +DER +EK E RE++K E+ +K E K+++ + K+ +
Sbjct: 391 KM-------RDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQE-QEKKTRDQ 442
Query: 371 LEKLRKVTGNEMLGLEEGDLEDDFDPAQHDQLMQKCFGDEYYGAVEEEKPQFEEEEGLE- 429
EK+++ EE E + + ++ M++ +EEK Q +EE E
Sbjct: 443 EEKMQE---------EERIREREKKMREEEETMRE----------QEEKMQKQEENMWEQ 483
Query: 430 DDWNWDTWDGPEQ-EGDWSQQELHCEDPNFNMDADYDPSQPRKKKREAPLTGKKKRKSPF 488
++ W PEQ E W Q+++ ++ Q K + + + G++K+
Sbjct: 484 EEKEWQQQRLPEQKEKLWEQEKMQEQEEKIW-------EQEEKIRDQEEMWGQEKK---- 532
Query: 489 AAAVGQEKPVFEPGDKTFEEYLDEYYRLDYEDIIDDLPCRFKYRTVVPCDFGLSTEEILA 548
+ +++ + E D+ +E+ E D E + D R + +T EE +
Sbjct: 533 ---MWRQEKMREQEDQMWEQ---EEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMR 586
Query: 549 ADDKELNRWCSLKKTCMYRSEQEELRDKRAYSQKAQNSWKKRQVFKSLCREEAETPAEAT 608
+++ R +++ EQEE ++ + Q Q K +EE E
Sbjct: 587 EEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEK 646
Query: 609 GKPQRDEAGPQRQLPALDGSLMG----PESPPAQEEEAPVSPHKKPAPQKRRRAKK 660
Q ++ Q++LP L E QE+E + +K + + + KK
Sbjct: 647 MWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKK 702
Score = 58.5 bits (140), Expect = 2e-08
Identities = 109/604 (18%), Positives = 249/604 (41%), Gaps = 46/604 (7%)
Query: 78 LLKKKDP---RIYQKDATFYNRTASSSDSEEDPEALEKQKKVRPMYLKDYERKVILEKAG 134
L K++D +Y+ T +++ +E E +K + +K+ +RK LE+A
Sbjct: 202 LTKERDALSLELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLNVKELKRK--LERAK 259
Query: 135 KYVDEENSDGETSNHRLQETSSQSYVEEQKQLKESFRAFVEDSEDEDGAGEGGSSLLQKR 194
+ + ++ QE + ++ ++ +E E +++G + ++
Sbjct: 260 FLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQ 319
Query: 195 AKTRQEKAQEEADYIEWLKGQKEIRNPDSLKELTHLKEYWNDPELDEGERFL-----RDY 249
K +E+ +E + + L+ QKE+R + + K + + ++ E E + R +
Sbjct: 320 EKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLW 379
Query: 250 ILNKRYEEEEEEEEDEEE--MEEEEGVHGPPVQLAVDDSSDEGELFLKKQEDFEQKYNFR 307
K+ E+E++ D+EE E++E + ++ + E +++++ +++
Sbjct: 380 EQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKT 439
Query: 308 FEEPDSASVKTYPRSIASSVRRKDERRKEKREETRERKKREKAKKQEELKQLKNLKRKEI 367
++ + + R +R ++E +E+ E+ +++++ ++++E +Q + ++KE
Sbjct: 440 RDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEK 499
Query: 368 LAKLEKLRKVTGNEMLGLEEGDLEDDFDPAQHDQLMQKCFGDEYYGAVEEEKPQFEEEEG 427
L + EK+++ E + +E + D + ++ M + + E++ Q E+E
Sbjct: 500 LWEQEKMQE--QEEKIWEQEEKIRDQEEMWGQEKKMWR------QEKMREQEDQMWEQEE 551
Query: 428 LEDDWNWDTWDGPEQ-EGDWSQQELHCEDPNFNMDADYDPSQPRKKKREAP---LTGKKK 483
D WD E+ E +QE D M + + KK RE ++K
Sbjct: 552 KMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEK 611
Query: 484 RKSPFAAAVGQEKPVFEPGDKTFEEYLDEYYRLDYEDIIDDLPCRFKYRTVVPCDFGLST 543
+ QE+ ++E +K E+ +E E + + ++ + + L
Sbjct: 612 MQEQEEKMQEQEEKMWEQEEKMQEQ--EEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWE 669
Query: 544 EEILAADDK----ELNRWCSLKKTCMYRSEQEELRDKRAYSQKAQNSWKKRQVFKSLCRE 599
E + +K E W ++ M + QE+ +K+ + Q+ + + + RE
Sbjct: 670 HEKMQEQEKMQEQEEKIW---EQEKMEKKTQEQ--EKKTWDQEKMREEESMREREKKMRE 724
Query: 600 EAETPAEATGKPQRDEAGPQRQLPALDGSLMGPESPPAQEEEAPVSPHKKPAPQKRRRAK 659
E E E K Q E Q Q E ++EE +K Q+R +
Sbjct: 725 EEEMMREQEEKMQEQEEKMQEQ-----------EEEMWEQEEKMWEQEEKMWEQQRLPEQ 773
Query: 660 KARL 663
K +L
Sbjct: 774 KEKL 777
Score = 48.5 bits (114), Expect = 2e-05
Identities = 89/460 (19%), Positives = 187/460 (40%), Gaps = 40/460 (8%)
Query: 189 SLLQKRAKTRQEKAQEEADYIEWLKGQKEIRNPDSLKELTHLKEYWNDPELDEGERFLRD 248
S K+A E+ +E D + + I N + K+ L+E E ++ E L
Sbjct: 189 STRHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLNV 248
Query: 249 YILNKRYEEEE------EEEEDEEEMEEEEGVHGPPVQLAVDDSSDEGELFLKKQEDFEQ 302
L ++ E + + +EEM +E + E E ++KQE+
Sbjct: 249 KELKRKLERAKFLLPQVQTNTLQEEMWRQE------------EELREQEKKIRKQEEKMW 296
Query: 303 KYNFRFEEPDSASVKTYPRSIASSVRRKDERRKEKREETRERKKREKAKKQEELKQLKNL 362
+ R E + ++ + +R E+ KE RE+ +E +++++ ++QEE Q +
Sbjct: 297 RQEERLREQEG-KMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEE 355
Query: 363 KRKEILAKLEKLRKVTGNEMLGLEEGDLEDDFDPAQHDQLMQKCFGDEYYGAVEEEKPQF 422
K E + EK+R+ +M EE E + + +Q M+ E ++E+ +
Sbjct: 356 KMWE---QEEKMREQE-EKMWRQEERLWEQEKQMREQEQKMRD---QEERMWEQDERLRE 408
Query: 423 EEEEGLEDDWNWDTWDGPEQEGDWSQQELHCEDPNFNMDADYDPSQPRKKKREAPLTGKK 482
+EE E + W+ + +E +QE D M + + KK RE T ++
Sbjct: 409 KEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMRE 468
Query: 483 KRKSPFAAAVGQEKPVFEPGDKTFEEYLDEYYRLDYEDIIDDLPCRFKYRTVVPCDFGLS 542
+ + QE+ ++E +K E+ + E + + + + + + +
Sbjct: 469 QEEK----MQKQEENMWEQEEK---EWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIR 521
Query: 543 TEEILAADDKELNRWCSLKKTCMYRSEQEE-LRDKRAYSQKAQNSWKKRQVFKSLCREEA 601
+E + +K++ R +++ EQEE +RD+ Q W + + + +E+
Sbjct: 522 DQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQE------QKMWDQEERMEKKTQEQE 575
Query: 602 ETPAEATGKPQRDEAGPQRQLPALDGSLMGPESPPAQEEE 641
+ + K + +E +R+ + M E +E+
Sbjct: 576 KKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQ 615
Score = 30.0 bits (66), Expect = 7.7
Identities = 35/205 (17%), Positives = 85/205 (41%), Gaps = 25/205 (12%)
Query: 15 QLRVNAAFAARYNRYREREELQRLKDRYGDRDSSSDSSSESDSSDERVEFDPQQERDFYK 74
++R + R + RE EE+ R + + E+ E +QE + ++
Sbjct: 708 KMREEESMREREKKMREEEEMMR---------------EQEEKMQEQEEKMQEQEEEMWE 752
Query: 75 TLSLLKKKDPRIYQKDATFYNRTASSSDSEEDPEALEKQKKV--RPMYLKDYERKVILEK 132
+ +++ +++++ R + + E +++Q+K+ + ++D E K+ ++
Sbjct: 753 QEEKMWEQEEKMWEQ-----QRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQE 807
Query: 133 AGKYVDEENSDGETSNHRLQETSSQSYVEEQKQLKESFRAFVEDSEDEDGAGEGGSSLLQ 192
EE G+ QE E+ +E E E++ E +
Sbjct: 808 EKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQE 867
Query: 193 KRAKTRQEKAQEEADYIEWLKGQKE 217
++ + ++EK +E+ E ++GQ+E
Sbjct: 868 EKMRGQEEKMREQE---EKMRGQEE 889
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 69.3 bits (168), Expect = 1e-11
Identities = 105/462 (22%), Positives = 191/462 (41%), Gaps = 59/462 (12%)
Query: 33 EELQRLKDRYGDRDSSSDSSSESDSSDERVEFDPQQERDFYKTLSLLKKKDPRIYQ---- 88
EE + + +R + S D SDE ++ Q+++ K P I
Sbjct: 165 EEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKN------QKNKPGPNIESGNED 218
Query: 89 KDATFYNRTASSSDSEEDPEALEKQKKVRPMYLKDYERKVILEKAGKYVDEENSDGETSN 148
DA+F +T + +E KK R +D E+ K K ++E + +
Sbjct: 219 DDASFKIKTVAQKKAE---------KKERERKKRDEEKA----KLRKLKEKEELETGKKD 265
Query: 149 HRLQETSSQSYVEEQKQLKESFRAFV----EDSEDEDGAGEGGSSLLQKRAKTRQEKAQE 204
Q+ S + + EE + K + V E+ + A E + +K+ +++K ++
Sbjct: 266 QSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEK 325
Query: 205 EADYIEWLKGQKEIRNPDSLKELTHLKEYWNDPELDEGERFLR-DYILNKRYEEEEEEEE 263
E E KG + + L LKE + +E ER R + + KR EEE E+E
Sbjct: 326 EEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQE 385
Query: 264 DEEEMEEEEGVHGPPVQLAVDDSSDEGELFLKKQEDFEQKYNFRFEEPDSASVKTYPRSI 323
E +++E ++ EG+L K Q + + A++K
Sbjct: 386 KRERKKQKEKERKERLK-------KEGKLLTKSQREARARAE--------ATLKLLQ--- 427
Query: 324 ASSVRRKDERRKEKREETRERKKREKAKKQEELKQLKNLKRKEILAKLEKL------RKV 377
A V + K+ E KKR+K +Q E K++ + E+ A +E + ++
Sbjct: 428 AQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVS--ESMELCAAVEVMEQGVPEKEE 485
Query: 378 TGNEMLGLEEGDLED----DFDPAQHDQLMQKCFGDEYYGAVEEEKPQFEEEEGLEDDWN 433
T + EE D ED D++ D+ +K G++ + V+E P+ EEEE E++ +
Sbjct: 486 TPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKEN-PEEEEEEEEEEEED 544
Query: 434 WDTWDGPEQEGDWSQQELHCEDPNFNMDADYDPSQPRKKKRE 475
++ + E+EG+ E ED + + D + +K +E
Sbjct: 545 EESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKE 586
Score = 60.5 bits (145), Expect = 5e-09
Identities = 75/345 (21%), Positives = 131/345 (37%), Gaps = 50/345 (14%)
Query: 31 EREELQRLKDRYGDRDSSSDSSSESDSSDERVEFDPQQERDFYKTLSLLKKKDPRIYQKD 90
+ E ++ KD+ + + E + QE L+ LK+++ R +++
Sbjct: 308 DNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQE-----ALAKLKEEEERQKREE 362
Query: 91 ATFYNRTASSSDSEEDPEALEKQKKVRPMYLKDYERKVILEKAGKY-------------- 136
R ++ E LE++K+ R K+ ERK L+K GK
Sbjct: 363 EERIKRLEELEAKRKEEERLEQEKRERKKQ-KEKERKERLKKEGKLLTKSQREARARAEA 421
Query: 137 ---------VDEENSDGETSNHRLQETSSQSYVEEQ---KQLKESFRAFVEDSEDEDGAG 184
V+ + D + E + + +Q K++ ES E G
Sbjct: 422 TLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVP 481
Query: 185 EGGSSLLQKRAKTRQEKAQEEADYIEW--LKGQKEIRNPDSLKELTHLKEYWNDPELDEG 242
E + + +E+ E+A +W + +E + K +KE +PE +E
Sbjct: 482 EKEET--PPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKE---NPEEEEE 536
Query: 243 ERFLRDYILNKRYEEEEEEEEDEEEMEEEEGVHGPPVQLAVDDSSDEGELFLKKQEDFEQ 302
E + EE+EE EE+EEE E EG G V D D G+ L K+ E
Sbjct: 537 EE--------EEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKT-LDKKPSKEM 587
Query: 303 KYNFRFEEPDSASVKTYPRSIASSVRRKDERRKEKREETRERKKR 347
+ ++ D + + R+ + RR ++RR E + K R
Sbjct: 588 SSDSEYDSDDDRTKE--ERAYDKAKRRIEKRRLEHSKNVNTEKLR 630
Score = 53.5 bits (127), Expect = 7e-07
Identities = 103/450 (22%), Positives = 182/450 (40%), Gaps = 72/450 (16%)
Query: 181 DGAGEGGSSLLQK-RAKTRQEKAQEEADYIEWLKGQKEI----RNPDSLKELTHLKEYWN 235
+GAG QK + K ++EK +++ D + LK +E+ + + +E +K N
Sbjct: 27 EGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKELEELSLEAQGIKADRETVAVKPTEN 86
Query: 236 -DPELDEGERFLRDYILNKRYEEEEEEEEDEEEMEEEEGVHGPPVQL-AVDDSSDEGELF 293
+ E ++ + K+ ++ + EE E++ + + P V++ + D D+
Sbjct: 87 NEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKL 146
Query: 294 LKKQEDFEQKYNFRF---EEPDSASVKTYPRSIASSVRRKDERRKEKREETRERKKREKA 350
KK + QK N ++ EE + S K RS +S + E + + +KK +K
Sbjct: 147 PKKAKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKN 206
Query: 351 KKQEELK----------QLKNLKRKEILAKLEKLRKVTGNEMLGLEEGDLEDDFDPAQHD 400
K ++ ++K + +K+ K E+ RK E L + +++ + + D
Sbjct: 207 KPGPNIESGNEDDDASFKIKTVAQKKA-EKKERERKKRDEEKAKLRKLKEKEELETGKKD 265
Query: 401 QLMQKCFGDEYYGAVEEEKPQFEEEEGLEDDWNWDTWDGPEQEGDWSQQELHCEDPNFNM 460
Q QK E + +FEEE ++ DT P E + ++ ED N
Sbjct: 266 QSKQK-----------ESQRKFEEET-VKSKVTVDTGVIPASE-EKAETPTAAEDDN--- 309
Query: 461 DADYDPSQPRKKKREAPLTGKKKRKSPFAAAVGQEKPVFEPGDKTFEEYLDEYYRLDYED 520
+ D +KKK E K+K+K P A V K + E K EE +E + + E+
Sbjct: 310 EGDKKKKDKKKKKGEKEEKEKEKKKGPSKATV---KAMQEALAKLKEE--EERQKREEEE 364
Query: 521 IIDDLPCRFKYRTVVPCDFGLSTEEILAADDKELNRWCSLKKTCMYRSEQEELRDKRAYS 580
I L EE+ A +E R EQE+ K+
Sbjct: 365 RIKRL------------------EELEAKRKEE------------ERLEQEKRERKKQKE 394
Query: 581 QKAQNSWKKRQVFKSLCREEAETPAEATGK 610
++ + KK + + EA AEAT K
Sbjct: 395 KERKERLKKEGKLLTKSQREARARAEATLK 424
Score = 53.1 bits (126), Expect = 9e-07
Identities = 79/381 (20%), Positives = 155/381 (40%), Gaps = 51/381 (13%)
Query: 31 EREELQRLKDRYGDRDSSSDSSSESDSSDERVEFDPQQERDFYKTLSLLKKKDPRIYQKD 90
+RE + + + +S + ++ FD + L+ KD + +K
Sbjct: 75 DRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEE-------LEDKDSKS-KKT 126
Query: 91 ATFYNRTASSSDSEEDPEALEKQKKVRPMYL-KDYERKVILEKAGKYVDEE---NSDGET 146
A S SD ++D L K+ K + K ++ E K + E NS GE+
Sbjct: 127 AKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGES 186
Query: 147 SNHRLQETSSQSYVEEQKQLKESFRAFVEDSEDEDGAGEGGSSLLQKRAKTRQEKAQEEA 206
+ + QS ++K K +E ++D A ++ QK+A+ ++E+ +++
Sbjct: 187 GDE--SDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAE-KKERERKKR 243
Query: 207 DYIEWLKGQKEIRNPDSLKELTHLKEYWNDPELDEGERFLRDYILNKRYEEEEEEEEDEE 266
D +E L++ EL+ G++ D K + + EEE +
Sbjct: 244 D-----------------EEKAKLRKLKEKEELETGKK---DQSKQKESQRKFEEETVKS 283
Query: 267 EMEEEEGV-------HGPPVQLAVDDSSDEGELFLKKQE-DFEQKYNFRFEEPDSASVKT 318
++ + GV P D+ D+ + KK++ + E+K + + P A+VK
Sbjct: 284 KVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKA 343
Query: 319 YPRSIASSVRRKDERRKEKREETRERKKREKAKKQE--------ELKQLKNLKRKEILAK 370
++A ++ +++E+ E + ++ E +K+E E K+ K +RKE L K
Sbjct: 344 MQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKK 403
Query: 371 LEKLRKVTGNEMLGLEEGDLE 391
KL + E E L+
Sbjct: 404 EGKLLTKSQREARARAEATLK 424
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 68.6 bits (166), Expect = 2e-11
Identities = 85/424 (20%), Positives = 190/424 (44%), Gaps = 43/424 (10%)
Query: 13 SSQLRVNAAFAARYNRYREREELQRLKDRYGDRDSSSDSSSESDSSDERVEFDPQQERDF 72
S++L+ +NR +++E + + ++ + + E+ E +QE
Sbjct: 278 SAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKM 337
Query: 73 YKTLSLLKKKDPRIYQKDATFYNRTASSSDSEEDPEALEKQKKVRPMYLKDYERKVILEK 132
+ ++ +K+ ++ +++ + + EE EK++K+R + K +E++ I E+
Sbjct: 338 RRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEE--MMWEKEEKIRELEEKMHEQEKIREQ 395
Query: 133 AGKYVDEENSDGETSNHRLQETSSQSYVEEQKQLKESFRAFVEDSEDEDGAGEGGSSLLQ 192
K +EE + QE ++ + +E+K R E +++ +
Sbjct: 396 EEKRQEEEKI---REQEKRQEQEAKMWRQEEK-----IREQEEKIREQEKKMWRQEEKIH 447
Query: 193 KRAKTRQEKAQEEADYIEWLKGQKEIRNPDSL---KELTHLKEYWNDPELDEGERFLRDY 249
++ K R+E+ ++E + E + +++IR + + KE H +E E E+ R
Sbjct: 448 EQEKIREEEKRQEQE--EMWRQEEKIREQEEIWRQKEKMHEQEKIRKQE----EKVWRQE 501
Query: 250 ILNKRYEEEEEEEEDEEEMEEEEGVHGPPVQLAVDDSSDEGELFLKKQEDFEQKYNFRFE 309
K +++EE+ E EE+M +E + ++ E +++E ++ E
Sbjct: 502 --EKMHDQEEKIREQEEKMWRQE-----------EKIREQEEKIREQEEKIREQEEMMQE 548
Query: 310 EPDSASVKTYPRSIASSVRRKDERRKEKREETRERKKREKAKKQEELKQLKNLKRKEILA 369
+ + + +RR++E+ +E+ E+ RE+K EK ++QEE K +++E +
Sbjct: 549 QEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQK--EKIREQEE----KIWEQEEKIR 602
Query: 370 KLEKLRKVTGNEMLGLEEGDLEDDFDPAQHDQLM----QKCFGDEYYGAVEEEKPQFEEE 425
+ E++ + +M EE E + + ++ M +K + E +EEK Q E +
Sbjct: 603 EQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQ-EHQ 661
Query: 426 EGLE 429
E LE
Sbjct: 662 EHLE 665
Score = 42.0 bits (97), Expect = 0.002
Identities = 78/402 (19%), Positives = 164/402 (40%), Gaps = 61/402 (15%)
Query: 309 EEPDSASVKTYPRSIASSVRRKDERRKEKREETRERKKREKAKKQEELKQLKNLKRKEIL 368
+E D+ S++ Y +I DE KEK + +E+ + +++K E +K LKRK
Sbjct: 200 KERDALSLELYRNTIT------DEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLER 253
Query: 369 AKL---------------EKLRKVTGNEMLGLEEGDLEDDFDPAQHDQL-MQKCFGDEYY 412
AKL ++L+ V+ +EE +L + + Q +++ Q+ E+
Sbjct: 254 AKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWE 313
Query: 413 GAVEEEKPQFEEEE----------GLEDDWNWD-----------TWDGPE-----QEGDW 446
++E++ + E+E +++ W+ W+ E +E W
Sbjct: 314 EKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMW 373
Query: 447 SQQELHCEDPNFNMDADYDPSQPRKKKREAPLTGKKKRKSPFAAAVGQEKPVFEPGDKTF 506
++E E + + Q K++ E + ++KR+ A QE+ + E +K
Sbjct: 374 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 433
Query: 507 EEYLDEYYRLDYEDIIDDLPCRFKYRTVVPCDFGLSTEEILAADDKELNRWCSLKKTCMY 566
E+ ++ E I + R + + + E+I + +E+ R +K M+
Sbjct: 434 EQ--EKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKI--REQEEIWR----QKEKMH 485
Query: 567 RSEQEELRDKRAYSQKA----QNSWKKRQVFKSLCREEAETPAEATGKPQRDEAGPQRQL 622
E+ ++++ + Q+ Q + Q K +EE E + Q ++ Q ++
Sbjct: 486 EQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEM 545
Query: 623 PALDGSLMGPESPPAQEEEAPVSPHKKPAPQKRR-RAKKARL 663
MG + QE+E +K Q+ + R +K ++
Sbjct: 546 MQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKI 587
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 67.0 bits (162), Expect = 6e-11
Identities = 88/451 (19%), Positives = 200/451 (44%), Gaps = 64/451 (14%)
Query: 29 YREREELQRLKDRYGDRDSSSDSSSESDSSDERVEFDPQQERDFYKTLSLLKKKDPRIYQ 88
+R+ E++Q +++ +++ E E E +QE ++ +++++ +++
Sbjct: 303 WRQEEKIQEWEEKIQEQEEKIREQEEKIREQE--EKMRRQEEMMWEKEEKMRRQEEMMWE 360
Query: 89 KDATFYNRTASSSDSEE-----DPEALEKQKKVRPMYLKDYERKVILEKAGKYVDEENSD 143
K+ + + EE + EK++K+R + K +E++ I E+ K +EE
Sbjct: 361 KEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKI- 419
Query: 144 GETSNHRLQETSSQSYVEEQKQLKESFRAFVEDSEDEDGAGEGGSSLLQKRAKTRQEKAQ 203
+ QE ++ + +E+K R E +++ + ++ K R+E+ +
Sbjct: 420 --REQEKRQEQEAKMWRQEEK-----IREQEEKIREQEKKMWRQEEKIHEQEKIREEEKR 472
Query: 204 EEADYIEWLKGQKEIRNPDSL---KELTHLKE---------YWNDPE-LDEGERFLRD-- 248
+E + E + +++I + + KE H +E W E + E E +R+
Sbjct: 473 QEQE--EMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQE 530
Query: 249 ---YILNKRYEEEEEEEEDEEEMEEEEGVHGPPVQLAVDDSSDEGELFLKKQED--FEQK 303
+ ++ E+EE +EE+M E+E + + +D E +++QE+ + Q+
Sbjct: 531 EKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQE 590
Query: 304 YNFRFEEPDSASVKTYPRSIASSVRRKDERRKEKREETRERKKREKAKKQEELKQLKNLK 363
R +E + +R ++E+ +E+ E+ RE++ EK ++QEE+ Q +
Sbjct: 591 EKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQE--EKIREQEEMTQ----E 644
Query: 364 RKEILAKLEKLRKVTGNEMLGLEEGDLEDDFDPAQHDQLMQKCFGDEYYGAVEEEKPQFE 423
++E + + E+ +M EE E + + ++ ++ E+EK E
Sbjct: 645 QEEKMGEQEE-------KMCEQEEKMQEQEETMWRQEEKIR-----------EQEKKIRE 686
Query: 424 EEEGLEDDWNWDTWDGPEQEGDWSQQELHCE 454
+EE + + + ++E W Q+E CE
Sbjct: 687 QEEKIREQ---EEMMQEQEEKMWEQEEKMCE 714
Score = 61.2 bits (147), Expect = 3e-09
Identities = 106/568 (18%), Positives = 232/568 (40%), Gaps = 55/568 (9%)
Query: 100 SSDSEEDPEALEKQKKVRPMYLKDYERKVILEKAGKYVDEENSDGETSNHRLQETSSQSY 159
+ + E+ A+ QKK Y+++ L K + E ++ L+E +++
Sbjct: 174 AGELEQALSAVATQKKKADRYIEE------LTKERDALSLELYRNTITDEELKEKNAK-- 225
Query: 160 VEEQKQLKESFRAFVEDSEDEDGAGEGGSSLLQKRAKTRQEKAQEEADYIEWLKGQKEIR 219
++E+ QL ES E SE + E L + + Q++ Q EAD++ KE++
Sbjct: 226 LQEKLQLVES-----EKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLG-----KELQ 275
Query: 220 NPDS-LKELTHLKEYWNDPELDEGERFLRDYILNKRYEEEEEEEEDEEEMEEEEGVHGPP 278
+ + L+ E WN + E+ R + +EE+ +E+E++ +EE+
Sbjct: 276 SVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEK------ 329
Query: 279 VQLAVDDSSDEGELFLKKQEDFEQKYNFRFEEPDSASVKTYPRSIASSVRRKDERRKEKR 338
++ + + E+ +K+E ++ +E+ + K +R
Sbjct: 330 IREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE----------------------KMRR 367
Query: 339 EETRERKKREKAKKQEELKQLKNLKRKEILAKLEKLRKVTGNEMLGLEEGDLEDDFDPAQ 398
+E +K EK ++QEE+ K K +E+ K+ + K+ E EE + + +
Sbjct: 368 QEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQE 427
Query: 399 HDQLM---QKCFGDEYYGAVEEEKPQFEEEEGL-EDDWNWDTWDGPEQEGDWSQQE-LHC 453
+ M ++ ++ E+EK + +EE + E + + EQE W Q+E +H
Sbjct: 428 QEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHE 487
Query: 454 EDPNFNM-DADYDPSQPRKKKREAPLTGKKKRKSPFAAAVGQEKPVFEPGDKTFEEYLDE 512
++ + + ++ + +K+ E ++K + QE+ ++ +K E+ +E
Sbjct: 488 QEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQ--EE 545
Query: 513 YYRLDYEDIIDDLPCRFKYRTVVPCDFGLSTEEILAADDKELNRWCSLKKTCMYRSEQEE 572
+R + + + + R E+I ++K + +++ R EQEE
Sbjct: 546 MWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEE 605
Query: 573 LRDKRAYSQKAQNSWKKRQVFKSLCREEAETPAEATGKPQRDEAGPQRQLPALDGSLMGP 632
K+ + Q + Q K +EE E + Q ++ G Q + M
Sbjct: 606 KMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQE 665
Query: 633 ESPPAQEEEAPVSPHKKPAPQKRRRAKK 660
+ +E + +K ++ + ++
Sbjct: 666 QEETMWRQEEKIREQEKKIREQEEKIRE 693
Score = 50.8 bits (120), Expect = 4e-06
Identities = 72/394 (18%), Positives = 170/394 (43%), Gaps = 34/394 (8%)
Query: 29 YREREELQRLKDRYGDRDSSSDSSSESDSSDERVEFDPQQERDFYKTLSLLKKKDPRIYQ 88
+ + E+++R ++ +++ E E++ ++ ++ K K+++
Sbjct: 373 WEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQE----- 427
Query: 89 KDATFYNRTASSSDSEEDPEALEKQKKVRPMYLKDYERKVILEKAGKYVDEENSDGETSN 148
++A + + + EE + E++KK+ K +E++ I E+ + EE E
Sbjct: 428 QEAKMWRQEEKIREQEE--KIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKI 485
Query: 149 HRLQETSSQS---YVEEQKQLKESFRAFVEDS---EDEDGAGEGGSSLLQKRAKTRQEKA 202
H +E Q + +E+K K+ + + ++ E E+ E + ++ K R+++
Sbjct: 486 HEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEE 545
Query: 203 QEEADYIEWLKGQKEIRNPDSLKELTHLKEYWNDPEL--DEGERFLRDYILNKRYEEEEE 260
+ E + Q++I + +E + W E ++ E+ R + E+ E
Sbjct: 546 MWREE--EKMHEQEKIWEEEKRQEQED--KMWRQEEKIREQEEKVWR------QEEKIRE 595
Query: 261 EEEDEEEMEE-----EEGVHGPPVQL-AVDDSSDEGELFLKKQEDFEQKYNFRFEEPDSA 314
+EE +E EE EE + ++ ++ E E +++QE+ Q+ + E +
Sbjct: 596 QEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEK 655
Query: 315 SVKTYPRSIASSVRRKDERRKEKREETRERKKREKAKKQEELKQLKNLK---RKEILAKL 371
+ + + K + +E + R++ EK ++QEE+ Q + K ++E + +
Sbjct: 656 MCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQ 715
Query: 372 EKLRKVTGNEMLGLEEGDLEDDFDPAQHDQLMQK 405
E+ + +M EE E + Q ++ MQ+
Sbjct: 716 EEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 749
Score = 48.5 bits (114), Expect = 2e-05
Identities = 54/352 (15%), Positives = 155/352 (44%), Gaps = 29/352 (8%)
Query: 28 RYREREELQRLKDRYGDRDSSSDSSSESDSSDERVEFDPQQERDFYKTLSLLKKKDPRIY 87
+ RE+EE ++ +++ +++ + ++ +E++ +QE + + +++ +I+
Sbjct: 405 KIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIR---EQEEKIREQEKKMWRQEEKIH 461
Query: 88 QKDATFYNRTASSSDSEED----PEALEKQKKVRPMYLKDYERKVILEKAGKYVDEENSD 143
+++ R +E+ E + +Q+++ K +E++ + K + V +
Sbjct: 462 EQEKI---REEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEK 518
Query: 144 GETSNHRLQETSSQSYVEEQKQLKESFRAFVEDSE--DEDGAGEGGSSLLQKRAKTRQEK 201
+++E + + +E+K ++E + E+ + +++ E Q+ RQE+
Sbjct: 519 IREQEEKIREQEEKMWRQEEK-IREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEE 577
Query: 202 AQEEADYIEWLKGQKEIRNPDSLKELTHLKEYWNDPELDEGERFLRDYILNKRYEEEEEE 261
E + W + +K IR + ++ K + + ++ E E +++ R +EE+
Sbjct: 578 KIREQEEKVWRQEEK-IREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIR 636
Query: 262 EEDEEEMEEEEGVHGPPVQLAVDDSS---------------DEGELFLKKQEDFEQKYNF 306
E++E E+EE + ++ + E E +++QE+ ++
Sbjct: 637 EQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEE 696
Query: 307 RFEEPDSASVKTYPRSIASSVRRKDERRKEKREETRERKKREKAKKQEELKQ 358
+E + + + + +++ K +R+E + ++ + ++QEE Q
Sbjct: 697 MMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQ 748
>gi|13540523 nucleosomal binding protein 1 [Homo sapiens]
Length = 282
Score = 66.6 bits (161), Expect = 7e-11
Identities = 60/218 (27%), Positives = 113/218 (51%), Gaps = 13/218 (5%)
Query: 192 QKRAKTRQEKAQEEADYIEWLK-GQKEIRN-PDSLKELTHLKEYWNDPELDEGERFLRDY 249
Q A+T+QE EE DY E K G+ +I P S KE+ +KE + ++G ++
Sbjct: 61 QAVAETKQEAVVEE-DYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGE-KKEA 118
Query: 250 ILNKRYEEEEEEEEDEEEMEEEEGVHGPPVQLAVDDSSDEGELFLKKQEDFEQKYNFRFE 309
+ + EEE+++EDEE+ EE+G G +D ++GE K+ ++ +K E
Sbjct: 119 VAAEVKNEEEDQKEDEEDQNEEKGEAGK------EDKDEKGEEDGKEDKNGNEKGEDAKE 172
Query: 310 EPDSASVKTYPRSIASSVRR-KDERRKEKREETRERKKREKAKKQEELKQLKNLKRKEIL 368
+ D + + + +DE+ +E R+ET + K+ E K++ + K+ K++K KE
Sbjct: 173 KEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDE 232
Query: 369 AKLEKLRKVTG--NEMLGLEEGDLEDDFDPAQHDQLMQ 404
+ E ++ G E G E+ DL+++ + + D++ +
Sbjct: 233 KEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKE 270
Score = 36.2 bits (82), Expect = 0.11
Identities = 61/274 (22%), Positives = 117/274 (42%), Gaps = 41/274 (14%)
Query: 47 SSSDSSSESDSSDERVEFDPQQERDFYKTLSLLKKKDPRIYQKDATFYNRTASSSDSEED 106
SS ++SD +E ++ Q ++ + K + ++D YN A + +++
Sbjct: 41 SSRKMKTKSDMMEENIDTSAQ---------AVAETKQEAVVEED---YNENAKNGEAKIT 88
Query: 107 PEALEKQKKVRPMYLKDYERKVILEKAGKYVDEENSDGETSNHRLQETSSQSYVEEQKQL 166
EA +K++ + +K+ + EK G+ +E E N + +E+ Q
Sbjct: 89 -EAPASEKEI--VEVKEENIEDATEKGGE--KKEAVAAEVKNEEEDQKE-----DEEDQN 138
Query: 167 KESFRAFVEDSEDEDGAGEGGSSLLQKRAKTRQEKAQEEADYIEWLKGQKEIRNPDSLKE 226
+E A ED +DE G +G K K EK ++ + + KG+ N + KE
Sbjct: 139 EEKGEAGKED-KDEKGEEDG------KEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKE 191
Query: 227 LTH-------LKEYWNDPELDEGERFLRDYILNKRYEEEEEEEEDEEEMEEEEGVHGPPV 279
KE + E ++G+ +K+ ++ + +EDE+E E+ + G
Sbjct: 192 KGEDEKEEEDRKETGDGKENEDGKEKG-----DKKEGKDVKVKEDEKEREDGKEDEGGNE 246
Query: 280 QLAVDDSSDEGELFLKKQEDFEQKYNFRFEEPDS 313
+ A + D E K+ED ++ + + EEP S
Sbjct: 247 EEAGKEKEDLKEEEEGKEEDEIKEDDGKKEEPQS 280
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 65.9 bits (159), Expect = 1e-10
Identities = 98/438 (22%), Positives = 185/438 (42%), Gaps = 46/438 (10%)
Query: 23 AARYNRYREREELQRLKDRYGDRDSSSDSSSESDSSDERVEFDPQQERDFYKTLSLLKKK 82
AAR R R R+E RL+ + + + ++ V P +E T + ++
Sbjct: 37 AARERRRRARQE--RLRQKQEEESLGQVTDQVEVNAQNSV---PDEEAKTTTTNTQVEGD 91
Query: 83 DPRIYQKDATFYNRTASSSDSEED--PEALEKQKKVRPMY----LKDYERKVILEKAGKY 136
D +A F R A + + EALE+QK+ P L R++ + A
Sbjct: 92 D------EAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENE 145
Query: 137 VDEENSDGETSNHRLQ----ETSSQSYVE----EQKQLKESFRAFVEDSEDEDGAGEGGS 188
E+ E+ R + ET ++SY + + ++ K+ + E+ E++ G G
Sbjct: 146 TTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGE 205
Query: 189 SLLQKRAKTRQEKAQEEADYIEWLKGQKEIRNPDSLKELTHLKEYWNDPELDEGERFLRD 248
+ ++ + + ++QEE + GQ P +E + + E E E R
Sbjct: 206 NQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERA 265
Query: 249 YILNKRYEEEEEE----EEDEEEMEEEEGVHGPPVQLAVDDSSDEGELF--LKKQEDFEQ 302
R E EE E E+D++ +E + A + E E ++++E
Sbjct: 266 EAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAA 325
Query: 303 KYNFRFEEPDSASVKTYPRSIASSVRRKDERRKEKREETR--ERKKREKAKKQEELKQLK 360
+ R +E + + + R R +ER++ K EE R E ++R +A+++E+ K +
Sbjct: 326 EERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEE 385
Query: 361 NLKRKEILAKLEKLR--KVTGNEMLGLEEGDLEDDFDPAQHDQL---MQKCFGDEYYGAV 415
+ K++ K ++ K+ G ++ EG ++ AQ D+L + K G+E V
Sbjct: 386 QKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNE-KKAQEDKLQTAVLKKQGEEKGTKV 444
Query: 416 -------EEEKPQFEEEE 426
+E+KP F++EE
Sbjct: 445 QAKREKLQEDKPTFKKEE 462
Score = 56.6 bits (135), Expect = 8e-08
Identities = 77/403 (19%), Positives = 170/403 (42%), Gaps = 55/403 (13%)
Query: 23 AARYNRYREREELQRLKDRYGDRDSSSDSSSESDSSDERVEFDPQQERDFYKTLSLLKKK 82
AA+ RE EE +R+++ E +++ER +++R + +K++
Sbjct: 302 AAQERERREAEERERMREE------------EKRAAEERQRIKEEEKRAAEER-QRIKEE 348
Query: 83 DPRIYQKDATFYNRTASSSDSEEDPEALEKQKKVRPMYLKDYERKVILEKAGKYVDEEN- 141
+ R ++ EE+ A E++++ R ++ + KV +K K ++E+
Sbjct: 349 EKRAAEERQRI---------KEEEKRAAEERQRARAE--EEEKAKVEEQKRNKQLEEKKH 397
Query: 142 --SDGETSNHRLQETSSQSYVEEQKQLKESFRAFVEDSEDEDGAGEGGSSLLQKRAKTRQ 199
+ + ++++ +V E+K ++ + V + E E G+ + KR K ++
Sbjct: 398 AMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGE----EKGTKVQAKREKLQE 453
Query: 200 EKAQEEADYIEWLKGQKEIRNPDSLKELTHLKEYWNDPELDEGERFLRDYILNKRYEEEE 259
+K + + I+ K +K+ + +K K+ + + + GE F+ + K E
Sbjct: 454 DKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGE-FMTHKL--KHTENTF 510
Query: 260 EEEEDEEEMEEEEGVHGPPVQLAVDDSSDEGELFLKKQEDFEQKYNFRFEEPDSASVKTY 319
++ +E P V+ EL ++ E +++ ++ A+++
Sbjct: 511 SRPGGRASVDTKEAEGAPQVEAG----KRLEELRRRRGETESEEFEKLKQKQQEAALE-- 564
Query: 320 PRSIASSVRRKDERRKEKREETRERKKREKAKKQEELKQLKNLKRKEILAKLEKLRKVTG 379
+ ++++ERRK EE + RK+ E +K E ++ + LK ++E+ R
Sbjct: 565 ---LEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKE-----EIERRRAEAA 616
Query: 380 NEMLGLEEGDLEDDFDPAQHDQLMQKCFGDEYYGAVEEEKPQF 422
+ + E L DD P KCF + EE+ +F
Sbjct: 617 EKRQKMPEDGLSDDKKPF-------KCFTPKGSSLKIEERAEF 652
Score = 35.4 bits (80), Expect = 0.18
Identities = 78/384 (20%), Positives = 152/384 (39%), Gaps = 59/384 (15%)
Query: 298 EDFEQKYNFRFEEPDSASVKTYPRSIASSVRRKDERRKEKREETRERKKREKAKKQEELK 357
+DFE++ R ++ + ++ + + ++E +E+R R+ + R+K +++E L
Sbjct: 2 DDFERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQK-QEEESLG 60
Query: 358 QLKNLKRKEILAKL----EKLRKVTGNEMLGLEEGDLEDDFDPAQHDQLMQKCFGDEYYG 413
Q+ + + E+ A+ E+ + T N + EGD E F +++
Sbjct: 61 QVTD--QVEVNAQNSVPDEEAKTTTTNTQV---EGDDEAAF--------LERL------- 100
Query: 414 AVEEEKPQFEEEEGLEDDWNWD--TWDGPEQEGDWSQQELHCEDPNFNMDADYDPSQPRK 471
A EE+ Q +E LE +D D Q E+ + + Q R
Sbjct: 101 ARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERY 160
Query: 472 KKREAPLTGKKKRKSPFAAAVGQEKPVFEPGDKTFEEYLDEYYRL------DYEDIIDDL 525
+ E K +K+ + A +K DK EE +E + E ++++
Sbjct: 161 EIEETETVTKSYQKNDWRDAEENKKE-----DKEKEEEEEEKPKRGSIGENQVEVMVEEK 215
Query: 526 PCRFKYRTVVPCDFGLSTEEILAADDKELNRWCSLKKTCMYRSEQEELRDKRAYSQKAQN 585
+ TVV L +I + + K+ + + EE +RA +++A+
Sbjct: 216 TTESQEETVV---MSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARL 272
Query: 586 SWKKRQVFKS---------LCREEAETPAEATGKPQRDEAGPQRQLPALDGSLMGPESPP 636
++R+ K+ R EAE A A + +R+ +R M E
Sbjct: 273 EAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERER---------MREEEKR 323
Query: 637 AQEEEAPVSPHKKPAPQKRRRAKK 660
A EE + +K A ++R+R K+
Sbjct: 324 AAEERQRIKEEEKRAAEERQRIKE 347
Score = 32.7 bits (73), Expect = 1.2
Identities = 70/353 (19%), Positives = 137/353 (38%), Gaps = 49/353 (13%)
Query: 329 RKDERRKEKREETRERKKREKAKKQEELKQLKNLKRKEILAKLEKLRKVTGNEMLGLEEG 388
R+ E R++KREE R +R ++ ++ ++ +R+ A+ E+LR+ E LG
Sbjct: 6 RRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRR-RARQERLRQKQEEESLGQVTD 64
Query: 389 DLEDDFDPAQHDQLMQ------KCFGDEYYGAVE-----EEKPQFEEEEGLEDDWNWDTW 437
+E + + D+ + + GD+ +E EE+ Q +E LE +D
Sbjct: 65 QVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPT 124
Query: 438 --DGPEQEGDWSQQELHCEDPNFNMDADYDPSQPRKKKREAPLTGKKKRKSPFAAAVGQE 495
D Q E+ + + Q R + E K +K+ + A +
Sbjct: 125 ITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENK 184
Query: 496 KPVFEPGDKTFEEYLDEYYRL------DYEDIIDDLPCRFKYRTVVPCDFGLSTEEILAA 549
K DK EE +E + E ++++ + TVV L +I +
Sbjct: 185 KE-----DKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVV---MSLKNGQISSE 236
Query: 550 DDKELNRWCSLKKTCMYRSEQEELRDKRAYSQKAQNSWKKRQVFKSLCREEAETPAEATG 609
+ K+ E+E+ D+ ++ +K + K+R EAE
Sbjct: 237 EPKQ-------------EEEREQGSDEISHHEKMEEEDKERA--------EAERARLEAE 275
Query: 610 KPQRDEAGPQRQLPALDGSLMGPESPPAQEEEAPVSPHKKPAPQKRRRAKKAR 662
+ +R +A +++ + E AQE E + ++ ++ +RA + R
Sbjct: 276 ERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEER 328
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 63.5 bits (153), Expect = 6e-10
Identities = 89/453 (19%), Positives = 196/453 (43%), Gaps = 55/453 (12%)
Query: 32 REELQRLKDRY---GDRDSSSDSSSESDSSDERVEFDPQQERDFYKTLSLLKKKDPRIYQ 88
R+ + RL D + G+ + + + + +R + +ERD LSL +Y+
Sbjct: 149 RDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERD---ALSL------ELYR 199
Query: 89 KDATFYNRTASSSDSEEDPEALEKQKKVRPMYLKDYERKVILEKAGKYVDEENSDGETSN 148
T ++ +E + +E +K + +K+ +RK LE+A + ++ E +
Sbjct: 200 NTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRK--LERAKLLLPQQQLQAEADH 257
Query: 149 HRLQETSSQSYVEEQKQLKESFRAFVEDSEDEDGAGEGGSSLLQKRAKTRQEKAQEEADY 208
+ S + ++ Q + E + + E++ E ++ + R+EK QE+ +
Sbjct: 258 LGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQE-------EKIQEREEKIQEQEEK 310
Query: 209 I----EWLKGQKEIRNPDSLKELTHLKEYWNDPE-LDEGERFLRDYILNKRYEEEEEEEE 263
I E ++ Q+E+ K + W E + E E + + K E+EE+ +E
Sbjct: 311 IREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQ--EKIREQEEKRQE 368
Query: 264 DEEEMEEEEGVHGPPVQLAVDDSSDEGELFLKKQEDFEQKYNFRFEEPDSASVKTYPRSI 323
+E+ E+E+ ++ E E +++QE+ Q+ + E + +
Sbjct: 369 EEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEE-------KMW 421
Query: 324 ASSVRRKDERRKEKREETRERKKREKAKKQEELKQLKNLKRKEILAKLEKLRKVTGNEML 383
+++ K +R+E + R++ +K ++QEE K +++E++ + E E +
Sbjct: 422 EQEEEMQEQEEKMRRQEEKIREQEKKIREQEE----KIREQEEMMQEQE--------EKM 469
Query: 384 GLEEGDL-EDDFDPAQHDQLMQKCFGDEYYGAVEEEKPQFEEEEGLEDDWNWDTWDGPEQ 442
G +EG + E + + ++ M++ + E+EK E+EE + + + ++
Sbjct: 470 GEQEGKMCEQEAKMQEQEEKMRR----QEEKIREQEKKIREQEEKIREQ---EEMMQEQE 522
Query: 443 EGDWSQQELHCEDPNFNMDADYDPSQPRKKKRE 475
E W Q+E CE + + + +K RE
Sbjct: 523 EKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMRE 555
Score = 56.6 bits (135), Expect = 8e-08
Identities = 62/344 (18%), Positives = 149/344 (43%), Gaps = 40/344 (11%)
Query: 32 REELQRLKDRYGDRDSSSDSSSESDSSDERV--EFDPQQERDFYKTLSLLKKKDPRIYQK 89
+++LQ D G S + ++ + + + QQE ++ +++++ +I ++
Sbjct: 248 QQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQ 307
Query: 90 DATFYNRTASSSDSEE------------DPEALEKQKKVRPMYLKDYERKVILEKAGKYV 137
+ + EE + EK++K+R + K +E++ I E+ K
Sbjct: 308 EEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQ 367
Query: 138 DEENSDGETSNHRLQETSSQSYVEEQKQLKESFRA---FVEDSEDEDGAGEGGSSLLQKR 194
+EE E + QE E+ ++ +E R +++ E++ G E ++
Sbjct: 368 EEEKIR-EQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEE 426
Query: 195 AKTRQEKAQEEADYIEWLKGQKEIRNPDSLKELTHLKEYWNDPELDEGERFLRDYILNKR 254
+ ++EK + + + I + +K+IR + +++ +E + E GE+ K
Sbjct: 427 MQEQEEKMRRQEEKIR--EQEKKIREQE--EKIREQEEMMQEQEEKMGEQE------GKM 476
Query: 255 YEEEEEEEEDEEEMEEEEGVHGPPVQLAVDDSSDEGELFLKKQEDFEQKYNFRFEEPDSA 314
E+E + +E EE+M +E + E E +++QE+ ++ +E +
Sbjct: 477 CEQEAKMQEQEEKMRRQE------------EKIREQEKKIREQEEKIREQEEMMQEQEEK 524
Query: 315 SVKTYPRSIASSVRRKDERRKEKREETRERKKREKAKKQEELKQ 358
+ + + +++ K +R+E + R++ + ++QEE Q
Sbjct: 525 MWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQ 568
Score = 45.4 bits (106), Expect = 2e-04
Identities = 70/338 (20%), Positives = 140/338 (41%), Gaps = 64/338 (18%)
Query: 309 EEPDSASVKTYPRSIASSVRRKDERRKEKREETRERKKREKAKKQEELKQLKNLKRKEIL 368
+E D+ S++ Y +I DE KEK + +E+ + +++K E +K LKRK
Sbjct: 188 KERDALSLELYRNTIT------DEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLER 241
Query: 369 AKL---------------EKLRKVTGNEMLGLEEGDLEDDFDPAQHDQLMQKCFGDEYYG 413
AKL ++L+ V+ +EE +L + + Q +++ ++ E
Sbjct: 242 AKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQ----EEKI 297
Query: 414 AVEEEKPQFEEEEGLEDD----------WNWDTWDGPEQEGDWSQQELHCEDPNFNMDAD 463
EEK Q +EE+ E + W + ++E W ++E E + +
Sbjct: 298 QEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQE 357
Query: 464 YDPSQPRKKKREAPLTGKKKRKSPFAAAVGQEKPVFEPGDKTFEEYLDEYYRLDYEDIID 523
Q K++ E + ++KR+ A QE+ + E +K E+ E + E+ +
Sbjct: 358 KIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQ---EEMMQEQEEKMG 414
Query: 524 DLPCRFKYRTVVPCDFGLSTEEILAADDKELNRWCSLKKTCMYRSEQEELRDKRAYSQKA 583
+ EE + ++E+ ++ R ++E++R++ +K
Sbjct: 415 E------------------QEEKMWEQEEEMQ-----EQEEKMRRQEEKIREQ---EKKI 448
Query: 584 QNSWKKRQVFKSLCREEAETPAEATGKPQRDEAGPQRQ 621
+ +K + + + +E+ E E GK EA Q Q
Sbjct: 449 REQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQ 486
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 60.8 bits (146), Expect = 4e-09
Identities = 74/266 (27%), Positives = 123/266 (46%), Gaps = 38/266 (14%)
Query: 27 NRYRERE-ELQRLKDRYGDRDSSSD-----SSSESDSSDERVEFDPQQERDFYKTLSLLK 80
+R +ER+ + R +DR DR+ SSD S S S D E + ++ER+ + +
Sbjct: 352 DRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERER 411
Query: 81 KKDPRIYQKDATFYNRTASSSDSEEDPE-ALEKQKKVRPMYLKDYERKVILE----KAGK 135
+++ R +++ D EED E A E++K R + K+ + L+ + K
Sbjct: 412 ERE-REREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERK 470
Query: 136 YVDEENSDGETSNHRLQETSSQSYVEEQKQLKESFRAFVED-SEDEDGAGEGGSSLLQKR 194
E + E R +E + +E K+LKE F+ED +D D S LQKR
Sbjct: 471 KTREYEKEAEREEERRREMA-----KEAKRLKE----FLEDYDDDRDDPKYYRGSALQKR 521
Query: 195 AKTRQEKAQ-EEADYIEWLKGQKEIR-------NPDSLKELTHLKEYWNDPELDEGERFL 246
+ R+++ + +E D + +EIR +PD EL +++ E ER
Sbjct: 522 LRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQ--------EAERRR 573
Query: 247 RDYILNKRYEEEEEEEEDEEEMEEEE 272
+ I + EEEEEE+ E+E + EE
Sbjct: 574 QPQIKQEPESEEEEEEKQEKEEKREE 599
Score = 57.4 bits (137), Expect = 5e-08
Identities = 77/346 (22%), Positives = 147/346 (42%), Gaps = 50/346 (14%)
Query: 30 REREELQRLKDRYGDRDSSSDSSSESDSSDERVEFDPQQERDFYKTLSLLKKKDPRIYQK 89
+ER E +R ++R +R ++ E + ++ERD + + + +D R ++
Sbjct: 307 KERRERERERERERERREREREREREREREKEKERERERERDRDRDRTKERDRD-RDRER 365
Query: 90 D-----ATFYNRTASSSDSEEDPEALEKQKKVRPMYLKDYERKVILEKAGKYVDEENSDG 144
D +R S S E E++++ ++ ER+ E+ + E +
Sbjct: 366 DRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERERERERERERER 425
Query: 145 ETSNHRLQETSSQSYVEEQK---QLKESFRAFVEDSEDEDGAGEGGSSLLQKRAKTRQEK 201
E R +E + E +K +L+E A+ E ++ + +++R KTR+ +
Sbjct: 426 EKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWE---------IRERKKTREYE 476
Query: 202 AQEEADYIEWLKGQKEIRNPDSLKELTHLKEYWNDPELDEGE-RFLRDYILNKRYEEEEE 260
+ E ++E R + KE LKE+ D + D + ++ R L KR + E+
Sbjct: 477 KEAE---------REEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREK 527
Query: 261 EEEDEE---EMEEEEGVHGPPVQLAVDDSSDEGELFLKKQEDFEQKYNFRFEEPDSASVK 317
E E +E + E+EE LA + EL +QE ++ +EP+S
Sbjct: 528 EMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPES---- 583
Query: 318 TYPRSIASSVRRKDERRKEKREETRERKKREKAKKQEELKQLKNLK 363
+E +EK+E +E K+ E +++EE +Q LK
Sbjct: 584 -------------EEEEEEKQE--KEEKREEPMEEEEEPEQKPCLK 614
Score = 52.8 bits (125), Expect = 1e-06
Identities = 101/471 (21%), Positives = 178/471 (37%), Gaps = 85/471 (18%)
Query: 45 RDSSSDSSSESDSSDERVEFDPQQER-DFYKTLSLLKKKD-PRIYQKDATFYNRTASSSD 102
R+ SS+ ++ S SD ++++ D ++ + P I ++D ++ +
Sbjct: 216 REYSSELNAPSQESDSHPRKKKKEKKEDIFRRFPVAPLIPYPLITKEDI-------NAIE 268
Query: 103 SEEDPEALEKQK--KVRPMYLKDYERKVILEKAGKYVDEENSDGETSNHRLQETSSQSYV 160
EED L ++ K R + K E K EK + +++E + E R +E +
Sbjct: 269 MEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERRERERE 328
Query: 161 EEQKQLKESFRAFVEDSE-DEDGAGEGGSSLLQKRAKTRQEKAQEEADYIEWLKGQKEIR 219
E+++ +E + + E D D + R K R E D + + R
Sbjct: 329 REREREREKEKERERERERDRD----------RDRTKERDRDRDRERD-----RDRDRER 373
Query: 220 NPDSLKELTHLKEYWNDPELD-EGERFLRDYILNKRYEEEEEEEEDEEEMEEEEGVHGPP 278
+ D K+ + +E D E + E ER +R E E E E E E E E+
Sbjct: 374 SSDRNKDRSRSREKSRDREREREREREREREREREREREREREREREREREREK------ 427
Query: 279 VQLAVDDSSDEGELFLKKQEDFEQKYNFR-FEEPDSASVKTYPRSIAS-SVR-RKDERRK 335
D D ++ED E Y R E Y + + +R RK R
Sbjct: 428 -----DKKRD-------REEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREY 475
Query: 336 EKREETRERKKREKAKKQEELKQLKNLKRKEILAKLEKLRKVTGNEMLGLEEGDLEDDFD 395
EK E E ++RE AK+ + LK+ LE+ D + D
Sbjct: 476 EKEAEREEERRREMAKEAKRLKEF-------------------------LEDYDDDRDDP 510
Query: 396 PAQHDQLMQKCFGDEYYGAVEEEKPQFEEEEGLEDDWNWDTWDG-PEQEGDWSQQELHCE 454
+QK D +E+ + E+E LE+ +G P+ + + + E E
Sbjct: 511 KYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAE 570
Query: 455 ---DPNFNMDADYDPSQPRKKKREAPLTGKKKRKSPF-AAAVGQEKPVFEP 501
P + + + + K+++E +KR+ P ++KP +P
Sbjct: 571 RRRQPQIKQEPESEEEEEEKQEKE------EKREEPMEEEEEPEQKPCLKP 615
Score = 44.3 bits (103), Expect = 4e-04
Identities = 66/343 (19%), Positives = 133/343 (38%), Gaps = 37/343 (10%)
Query: 28 RYRERE-ELQRLKDRYGDRDSSSDSSSESDSSDERVEFDPQQERDFYKTLSLLKKKDPRI 86
R RERE E +R KD+ DR+ + + E + ++ ++ K + ++K R
Sbjct: 415 REREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTRE 474
Query: 87 YQKDATFYNRTASSSDSEEDPEALEKQKKVRPMYLKDY--ERKVILEKAGKYVDEENSDG 144
Y+K+A EE + K+ K +L+DY +R G + + D
Sbjct: 475 YEKEA---------EREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDR 525
Query: 145 ETSNHRLQETSSQSYVEEQKQLKESFRAFVEDSEDEDGAGEGGSSLLQKRAKTRQEKAQE 204
E + E + E+++L+E + + + + A +R + Q K +
Sbjct: 526 E----KEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEP 581
Query: 205 EADYIEWLKGQKEIRNPDSLKELTH----------LKEYWNDPELDEGERFLRDYILNKR 254
E++ E K +KE + + ++E L+ + P + + N
Sbjct: 582 ESEEEEEEKQEKEEKREEPMEEEEEPEQKPCLKPTLRPISSAPSVSSAS---GNATPNTP 638
Query: 255 YEEE-------EEEEEDEEEMEEEEGVHGPPVQLAVDDSSDEGELFLKKQEDFEQKYNFR 307
+E E D+++ EE G ++L +S + +K+ + +N +
Sbjct: 639 GDESPCGIIIPHENSPDQQQPEEHRPKIGLSLKLGASNSPGQPNSVKRKKLPVDSVFN-K 697
Query: 308 FEEPDSASVKTYPRSIASSVRRKDERRKEKREETRERKKREKA 350
FE+ DS V + + D+ + T E++K K+
Sbjct: 698 FEDEDSDDVPRKRKLVPLDYGEDDKNATKGTVNTEEKRKHIKS 740
Score = 30.8 bits (68), Expect = 4.5
Identities = 36/189 (19%), Positives = 80/189 (42%), Gaps = 31/189 (16%)
Query: 202 AQEEADYIEWLKGQKEIRNPDSLKE-LTHLKEYWNDPELDEGERFLRDYI---------- 250
A+ +A EW K +K+ N ++ E +T+ E D E ++ ++ I
Sbjct: 163 AKTKAQLDEW-KAKKKASNGNARPETVTNDDEEALDEETKRRDQMIKGAIEVLIREYSSE 221
Query: 251 LNKRYEEEEEEEEDEEEMEEEEGVHGPPVQL-------------AVDDSSDEGELFLKKQ 297
LN +E + +++ ++E+ PV A++ D+ +L ++
Sbjct: 222 LNAPSQESDSHPRKKKKEKKEDIFRRFPVAPLIPYPLITKEDINAIEMEEDKRDLISREI 281
Query: 298 EDFEQKYNFRFEEPDSASVKTYPRSIASSVRRKDERRKEKREETRERKKREKAKKQEELK 357
F + + EE K + ++ R+ +RE RER++RE+ +++E +
Sbjct: 282 SKFRDTHK-KLEEEKGKKEKE-----RQEIEKERRERERERERERERRERERERERERER 335
Query: 358 QLKNLKRKE 366
+ + + +E
Sbjct: 336 EKEKERERE 344
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 60.1 bits (144), Expect = 7e-09
Identities = 72/422 (17%), Positives = 181/422 (42%), Gaps = 52/422 (12%)
Query: 100 SSDSEEDPEALEKQKKVRPMYLKDYERKV------------ILEKAGKYVDEENS----D 143
+++ +E+ + +E +K +++K+ +RK+ + E+ G+ ++E +
Sbjct: 13 NAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEGQVREQE 72
Query: 144 GETSNHRLQETSSQSYVEEQK-QLKESFRAFVEDS----EDEDGAGEGGSSLLQKRAKTR 198
G+ Q + V EQ+ Q++E E E E E + ++ + R
Sbjct: 73 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 132
Query: 199 QEKAQ--EEADYIEWLKGQKEIRNPDSLKELTHLKEYWNDPELDEGERFLRDYILNKRYE 256
+++ Q E+ + +GQ + ++ ++E EG+ ++ + ++
Sbjct: 133 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 192
Query: 257 EEEEEEEDEEEMEEEEGVHGPPVQLAVDDSSDEGELFLKKQED--FEQKYNFRFEEPDSA 314
+ E+E E EE+ G E E ++KQE+ EQ+ R +E
Sbjct: 193 QMGEQEGQMGEQEEQMG---------------EQEEQMQKQEEQMGEQEEQMRKQEEQMG 237
Query: 315 SVKTYPRSIASSVRRKDERRKEKREETRERKKREKAKKQEELKQLKNLKRKEILAKLEKL 374
+ + V++++E+ +++ E+ RE++++ + ++++ LKQ + +++E + E+
Sbjct: 238 EQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQ 297
Query: 375 RKVTGNEMLGLEEGDLEDDFDPAQHDQLMQKCFGDEYYGAVEEEKPQFEEEEGLEDDWNW 434
+ +M EE E + + ++ M K +E+ +E++E + +
Sbjct: 298 MREQEEQMREQEEQMREQEEQMREQEEQMGK-----------QEEQMWEQKEQMWEQ-KE 345
Query: 435 DTWDGPEQEGDWSQQELHCEDPNFNMDADYDPSQPRKKKREAPLTGKKKRKSPFAAAVGQ 494
W EQ G+ +Q E+ + + + +K+E + ++++ +G+
Sbjct: 346 QMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGE 405
Query: 495 EK 496
+K
Sbjct: 406 QK 407
Score = 51.6 bits (122), Expect = 2e-06
Identities = 82/464 (17%), Positives = 187/464 (40%), Gaps = 35/464 (7%)
Query: 190 LLQKRAKTRQEKAQEEADYIEWLKGQKEIRNPDSLKELTHLKEYWNDPELDEGERFLRDY 249
+ + K + + QEE +E K + ++ +KEL E P EG+ +R+
Sbjct: 4 ITNEELKEKNAELQEELQLVETEKSEIQLH----IKELKRKLETDKIPLPQEGQ--VREQ 57
Query: 250 ILNKRYEEEEEEEEDEEEMEEEEGVHGPPVQLAVDDSS---DEGELFLKKQEDFEQKYNF 306
R +E + E++ + E+E V Q+ + EG++ ++ + EQ+
Sbjct: 58 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 117
Query: 307 RFEEPDSASVKTYPRSIASSVRRKDERRKEKREETRERKKREKAKKQEELKQLKNLKRKE 366
R +E + R VR ++ + +E+ + RE++ + + ++ + +Q ++ +E
Sbjct: 118 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE 177
Query: 367 ILAKLEKLRKVTGNEMLGLEEGDL-EDDFDPAQHDQLMQKCFGDEYYGAVEEEKPQFEEE 425
+ ++ + +G +EG + E + + ++ MQK +E G EE+ + EE+
Sbjct: 178 GQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQK--QEEQMGEQEEQMRKQEEQ 235
Query: 426 EGLEDDWNWDTWDGPEQEGDWSQQELHCEDPNFNMDADYDPSQPRKKKREAPLTGKKKRK 485
G ++ EQ +Q E+ + + + +++E + +K++
Sbjct: 236 MGEQE----------EQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQT 285
Query: 486 SPFAAAVGQEKPVFEPGDKTFEEYLDEYYRLDYEDIIDDLPCRFKYRTVVPCDFGLSTEE 545
QE+ + E ++ E+ +E R E + + G E+
Sbjct: 286 EQEEQTGEQEEQMREQEEQMREQ--EEQMREQEEQMREQEE-----------QMGKQEEQ 332
Query: 546 ILAADDKELNRWCSLKKTCMYRSEQEELRDKRAYSQKAQNSWKKRQVFKSLCREEAETPA 605
+ ++ + + K EQEE K+ + Q ++Q + +EE
Sbjct: 333 MWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQ 392
Query: 606 EATGKPQRDEAGPQRQLPALDGSLMGPESPPAQEEEAPVSPHKK 649
E Q+++ G Q++ MG + +++E + K+
Sbjct: 393 EEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436
Score = 50.1 bits (118), Expect = 7e-06
Identities = 66/357 (18%), Positives = 160/357 (44%), Gaps = 28/357 (7%)
Query: 104 EEDPEALEKQKKVRPMYLKDYERK-VILEKAGKYVDEENS----DGETSNHRLQETSSQS 158
E++ + E++ +VR + E++ + E+ G+ ++E +G+ Q +
Sbjct: 84 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 143
Query: 159 YVEEQKQLKESFRAFVEDSEDEDGAGEGGSSLLQKRAKTRQEKAQEEADYIEWLKGQKEI 218
V EQ+ V + E + EG + ++ + R+++ Q E G++E
Sbjct: 144 QVREQEGQVREQEGQVREQEGQVREQEG--QVREQEGQVREQEGQVREQ--EGQMGEQEG 199
Query: 219 RNPDSLKELTHLKEYWNDPELDEGERF----LRDYILNKRYEEEEEEEEDEEEMEEEEGV 274
+ + +++ +E E GE+ ++ + ++ E+ +++EE ++ EE+
Sbjct: 200 QMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRK 259
Query: 275 HGPPVQLAVDDSSDEGELFLKKQEDFEQKYNFRFEEPDSASVKTYPRSIASSVRRKDERR 334
++ + ++ E LK++E EQ E + + R +R ++E+
Sbjct: 260 QEEQMREQEEQMREQEEQMLKQKEQTEQ-------EEQTGEQEEQMREQEEQMREQEEQM 312
Query: 335 KEKREETRERKKREKAKKQEELKQLKN--LKRKEILAKLEKLRKVTGNEMLGLEEGDLED 392
+E+ E+ RE+++ + K++E++ + K ++KE + K E+ +M EE +
Sbjct: 313 REQEEQMREQEE-QMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQ 371
Query: 393 DFDPAQHDQLMQKCFGDEYYGAVEEEKPQFEEEEGLEDDWNWDTWDGPEQEGDWSQQ 449
+ + ++ M+K +E EE+ + +E+ G + + + EQ G+ +Q
Sbjct: 372 EEQMRKQEEQMRK--QEEQMRKQEEQMGEQKEQMGEQKE---QMREQEEQMGEQKEQ 423
Score = 32.7 bits (73), Expect = 1.2
Identities = 33/126 (26%), Positives = 53/126 (42%), Gaps = 10/126 (7%)
Query: 328 RRKDERRKEKREETRERKKREKAKKQEELKQLKNLKRKEILAKLEKLRKVTGNEMLGL-- 385
R +E KEK E +E + + +K E +K LKRK K+ ++ E G
Sbjct: 3 RITNEELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVR 62
Query: 386 -EEGDLEDDFDPAQHDQLMQKCFGDEYYGAVEEEKPQFEEEEGLEDDWNWDTWDGPEQEG 444
+EG + + + + + E G V E++ Q E+EG + EQEG
Sbjct: 63 EQEGQVREQEGQVREQEGQVR----EQEGQVREQEGQVREQEGQVREQEGQV---REQEG 115
Query: 445 DWSQQE 450
+QE
Sbjct: 116 QVREQE 121
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 60.1 bits (144), Expect = 7e-09
Identities = 78/412 (18%), Positives = 186/412 (45%), Gaps = 21/412 (5%)
Query: 29 YREREELQRLKDRYGDRDSSSDSSSESDSSDERVEFDPQQERDFYKTLSLLKKKDP---R 85
+R+R +++ R G+ ++ E+ +E + FD Y L K++D
Sbjct: 149 FRKRVVIKKPWLRLGE--VTAQKRPENSLLEETLHFDHAVRMGTYIE-KLTKERDAPSLE 205
Query: 86 IYQKDATFYNRTASSSDSEEDPEALEKQKKVRPMYLKDYERKVILEKAGKYVDEENSDGE 145
+Y+ T +++ +E +E +K + +KD +RK LE+A + ++ E
Sbjct: 206 LYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRK--LERAQLLLPQQQLQVE 263
Query: 146 TSNHRLQETSSQSYVEEQKQLKESFRAFVEDSEDEDGAGEGGSSLLQKRAKTRQEKAQEE 205
+ S + ++ Q + E + + E++ E +++ ++ K +E+
Sbjct: 264 ADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQ 323
Query: 206 ADYIEWLKGQKEIRNPDSLKELTHLKEYWNDPELDEGERFLRDYILNKRYEEEEEEEEDE 265
+ + W + +K + ++E K + + ++ E E +R+ +EE+ E+DE
Sbjct: 324 EEKM-WRQEEKMHEQEEKIREQED-KMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDE 381
Query: 266 EEMEEEEGVHGPPVQLAVDDSSDEGELFLKKQEDFEQKYNFRFEEPDSASVKTYPRSIAS 325
+ E+EE + ++ + + +++ ++++ EQ R +E + + R +
Sbjct: 382 KIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEE 441
Query: 326 SVRRKDERRKE-----KREETRERKKREKAKKQEELKQLKNLK--RKEILAKLEKLRKVT 378
++ ++E+ +E + EE + +++ EK ++QEE Q + K R+E L K E+
Sbjct: 442 MMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQ 501
Query: 379 GNEMLGLEEGDLEDDFDPAQHDQLMQKCFGDEYYGAVEEEKPQFEEEEGLED 430
+M EE E + + ++ MQ+ + E+E +++EE +++
Sbjct: 502 EEKMWRQEEKMWEQEEKMQEQEEKMQR----QEEKMREQEVRLWQQEEKMQE 549
Score = 47.0 bits (110), Expect = 6e-05
Identities = 62/302 (20%), Positives = 132/302 (43%), Gaps = 47/302 (15%)
Query: 104 EEDPEALEKQKKVRPMYLKDYERKVILEKAGKYVDEENSDGETSNHRLQETSSQSYVEEQ 163
E++ + E++ K+R K + ++ + + + + E+ +++E + +E+
Sbjct: 308 EQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEE 367
Query: 164 KQLKESFRAFVEDSEDEDGAGEGGSSLLQKRAKTRQEKAQEEADYIEWLKGQKEIRNPDS 223
K ++ + +D + ++ E +++ + ++EK QE+ W + +K +
Sbjct: 368 KMWRQEEKIREQDEKIQEQEEEMWRQ--EEKIREQEEKRQEKM----WRQEKKMREQDEK 421
Query: 224 LKELTHLKEYWNDPE-LDEGERFLRDY------ILNKRYEEEEEEEEDEEE--------M 268
++E +E W E + E E ++D + K EEEE+ +E EE+
Sbjct: 422 IREQE--EEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQ 479
Query: 269 EEEEGVHGPPVQLAVDDSSDEGELFLKKQED--FEQKYNFRFEEPDSASVKTYPRSIASS 326
E+EE L ++ E E + +QE+ +EQ+ + +E
Sbjct: 480 EQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQE---------------- 523
Query: 327 VRRKDERRKEKREETRERKKREKAKKQEELKQLKNLKRKEILAKLEKLRKVTGNEMLGLE 386
K +R++EK E R +++ K QE+ +L+ L +E L KL + ++ G G E
Sbjct: 524 --EKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQEL--EERLGKLGQKAELLGG--AGRE 577
Query: 387 EG 388
G
Sbjct: 578 SG 579
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 60.1 bits (144), Expect = 7e-09
Identities = 78/412 (18%), Positives = 186/412 (45%), Gaps = 21/412 (5%)
Query: 29 YREREELQRLKDRYGDRDSSSDSSSESDSSDERVEFDPQQERDFYKTLSLLKKKDP---R 85
+R+R +++ R G+ ++ E+ +E + FD Y L K++D
Sbjct: 149 FRKRVVIKKPWLRLGE--VTAQKRPENSLLEETLHFDHAVRMGTYIE-KLTKERDALSLE 205
Query: 86 IYQKDATFYNRTASSSDSEEDPEALEKQKKVRPMYLKDYERKVILEKAGKYVDEENSDGE 145
+Y+ T +++ +E +E +K + +KD +RK LE+A + ++ E
Sbjct: 206 LYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRK--LERAQLLLPQQQLQVE 263
Query: 146 TSNHRLQETSSQSYVEEQKQLKESFRAFVEDSEDEDGAGEGGSSLLQKRAKTRQEKAQEE 205
+ S + ++ Q + E + + E++ E +++ ++ K +E+
Sbjct: 264 ADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQ 323
Query: 206 ADYIEWLKGQKEIRNPDSLKELTHLKEYWNDPELDEGERFLRDYILNKRYEEEEEEEEDE 265
+ + W + +K + ++E K + + ++ E E +R+ +EE+ E+DE
Sbjct: 324 EEKM-WRQEEKMHEQEEKIREQED-KMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDE 381
Query: 266 EEMEEEEGVHGPPVQLAVDDSSDEGELFLKKQEDFEQKYNFRFEEPDSASVKTYPRSIAS 325
+ E+EE + ++ + + +++ ++++ EQ R +E + + R +
Sbjct: 382 KIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEE 441
Query: 326 SVRRKDERRKE-----KREETRERKKREKAKKQEELKQLKNLK--RKEILAKLEKLRKVT 378
++ ++E+ +E + EE + +++ EK ++QEE Q + K R+E L K E+
Sbjct: 442 MMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQ 501
Query: 379 GNEMLGLEEGDLEDDFDPAQHDQLMQKCFGDEYYGAVEEEKPQFEEEEGLED 430
+M EE E + + ++ MQ+ + E+E +++EE +++
Sbjct: 502 EEKMWRQEEKMWEQEEKMQEQEEKMQR----QEEKMREQEVRLWQQEEKMQE 549
Score = 47.0 bits (110), Expect = 6e-05
Identities = 62/302 (20%), Positives = 132/302 (43%), Gaps = 47/302 (15%)
Query: 104 EEDPEALEKQKKVRPMYLKDYERKVILEKAGKYVDEENSDGETSNHRLQETSSQSYVEEQ 163
E++ + E++ K+R K + ++ + + + + E+ +++E + +E+
Sbjct: 308 EQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEE 367
Query: 164 KQLKESFRAFVEDSEDEDGAGEGGSSLLQKRAKTRQEKAQEEADYIEWLKGQKEIRNPDS 223
K ++ + +D + ++ E +++ + ++EK QE+ W + +K +
Sbjct: 368 KMWRQEEKIREQDEKIQEQEEEMWRQ--EEKIREQEEKRQEKM----WRQEKKMREQDEK 421
Query: 224 LKELTHLKEYWNDPE-LDEGERFLRDY------ILNKRYEEEEEEEEDEEE--------M 268
++E +E W E + E E ++D + K EEEE+ +E EE+
Sbjct: 422 IREQE--EEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQ 479
Query: 269 EEEEGVHGPPVQLAVDDSSDEGELFLKKQED--FEQKYNFRFEEPDSASVKTYPRSIASS 326
E+EE L ++ E E + +QE+ +EQ+ + +E
Sbjct: 480 EQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQE---------------- 523
Query: 327 VRRKDERRKEKREETRERKKREKAKKQEELKQLKNLKRKEILAKLEKLRKVTGNEMLGLE 386
K +R++EK E R +++ K QE+ +L+ L +E L KL + ++ G G E
Sbjct: 524 --EKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQEL--EERLGKLGQKAELLGG--AGRE 577
Query: 387 EG 388
G
Sbjct: 578 SG 579
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 58.2 bits (139), Expect = 3e-08
Identities = 97/411 (23%), Positives = 168/411 (40%), Gaps = 80/411 (19%)
Query: 53 SESDSSDERVEFDPQQERDFYKTLSLLKK-KDPRIYQKDATFYNRTASSSDSEEDPEALE 111
+E+D SDE Y+ +S +K+ K + + F + A++ ++ D E
Sbjct: 539 TENDDSDE------------YEEMSEMKEGKACKQHVSQGIFMTQPATTIEAFSDEEVEI 586
Query: 112 KQKKVRPMYLKDYERKVILEKAGKYVDEENSDGETSNHRLQETSSQSYVEEQKQLKESFR 171
++K K +E+ +EEN E S ++ + + +
Sbjct: 587 PEEKEGAEDSKGNG----IEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAEVSEGKAK 642
Query: 172 AFVEDSEDEDGAGEG----GSSLLQKRAKTRQEKAQEEADYIEWLKGQKEIRNP-DSLKE 226
+ E + +G G+G GSS + +EK +++ KG+ E+ P + KE
Sbjct: 643 SVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKD-------KGRGEMERPGEGEKE 695
Query: 227 LTHLKEYWNDPELDEGERFLRDYILNKRYEEEEEE--EEDEEEMEEEEGVHGPPVQLAVD 284
L KE W + +E E+ R+ K +E EE EE+ E EEEEG
Sbjct: 696 LAE-KEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEG----------- 743
Query: 285 DSSDEGELFLKKQEDFEQKYNFRFEEPDSASVKTYPRSIASSVRRKDERRKEKREETRER 344
+E+ E+K EE + V+ R K+E ++K E +
Sbjct: 744 -----------DREEEEEKEGEGKEEGEGEEVE--------GEREKEEGERKKEERAGKE 784
Query: 345 KKREKAKKQEELKQLKNLKRKEILAKLEKLRKVTGNEMLGLEEGDLEDDFDPAQHDQLMQ 404
+K E+ Q E ++ + R E + E+ +V G E +EEG E + + + +
Sbjct: 785 EKGEEEGDQGEGEEEETEGRGE---EKEEGGEVEGGE---VEEGKGEREEEEEEGE---- 834
Query: 405 KCFGDEYYGAVEEEKPQFEEEEG-----LEDDWNWDTWDGPEQEGDWSQQE 450
G+E G EEE+ + EEEEG E + +G E EG+ ++E
Sbjct: 835 ---GEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEE 882
Score = 55.8 bits (133), Expect = 1e-07
Identities = 98/493 (19%), Positives = 196/493 (39%), Gaps = 42/493 (8%)
Query: 33 EELQRLKDRYGDRDSSSDSSSESD--SSDERVEFDPQQERDFYKTLSLLKKKDPRIYQKD 90
EE++ +++ G DS + E + +++E V+ ++ KT L + K
Sbjct: 582 EEVEIPEEKEGAEDSKGNGIEEQEVEANEENVKVHGGRKE---KTEIL----SDDLTDKA 634
Query: 91 ATFYNRTASSSDSEEDPEALE----KQKKVRPMYLKDYERKVILEKAGKYVDEENSDGET 146
+ S ++E+ PE ++ + +D ER+ + G+ E +GE
Sbjct: 635 EVSEGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEK 694
Query: 147 SNHRLQETSSQSYVEEQKQLKESFRAFVEDSEDEDGA----GEGGSSLLQKRAKTRQEKA 202
+E + E++++ +E + E E+G GEG + + +E
Sbjct: 695 ELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGE 754
Query: 203 QEEADYIEWLKGQKEIRNPDSLKELTHLKEYWNDPELDEGERFLRDYILNKRYEEEEEEE 262
+E E ++G++E + KE KE + E D+GE EEEE E
Sbjct: 755 GKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEG------------EEEETE 802
Query: 263 EDEEEMEEEEGVHGPPVQLAV---DDSSDEGELFLKKQEDFEQKYNFRFEEPDSASVKTY 319
EE EE V G V+ ++ +EGE ++ E E++ EE + +
Sbjct: 803 GRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEG 862
Query: 320 PRSIASSVRRKDERRKEKREETRERKKREKAKKQEELKQLKNLKRKEILAKLEKLRKVTG 379
+ E E+ E E ++ + + +EE E + E+ + G
Sbjct: 863 EEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEE----------EGEGEGEEEGEGEG 912
Query: 380 NEMLGLEEGDLEDDFDPAQHDQLMQKCFGDEYYGAVEEEKPQFEEEEGLEDDWNWDTWDG 439
E G +G+ E + + ++ + G++ G EEE+ ++E EE + + +G
Sbjct: 913 EEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEG 972
Query: 440 PEQEGDWSQQELHCEDPNFNMDADYDPSQPRKKKREAPLTGKKKRKSPFAAAVGQEKPVF 499
+EG+ +E E + + + + + + E G+++ + V E+
Sbjct: 973 EGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEG 1032
Query: 500 EPGDKTFEEYLDE 512
E ++ EE +E
Sbjct: 1033 EGEEEEGEEEGEE 1045
Score = 50.1 bits (118), Expect = 7e-06
Identities = 81/367 (22%), Positives = 150/367 (40%), Gaps = 26/367 (7%)
Query: 33 EELQRLKDRYGDRDSSSDSSSESDSSDERVEFDPQQERDFYKTLSLLKKKDPRIYQKDAT 92
EE ++ GDR+ + E E E + ++E++ + +KK+ R +++
Sbjct: 733 EEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGE-----RKKEERAGKEEKG 787
Query: 93 FYNRTASSSDSEEDP---EALEKQKKVRPMYLKDYERKVILEKAGKYVDEENSDGETSNH 149
+ EE E E+ +V +++ + + E+ +EE +GE
Sbjct: 788 EEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEG 847
Query: 150 RLQETSSQSYVEEQKQLKESFRAFVE---DSEDEDGAGEGGSSLLQKRAKTRQEKAQEEA 206
+E + EE+ + E E + E+E+G GEG ++ + E+ + E
Sbjct: 848 EGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEG-----EEEGEGEGEEEEGEG 902
Query: 207 DYIEWLKGQKEIRNPDSLKELTHLKEYWNDPELDEGERFLRDYILNKRYEEEE---EEEE 263
+ E +G+ E + E +E + E +EGE D EE E EEEE
Sbjct: 903 EGEEEGEGEGEEEEGEGKGE-EEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEE 961
Query: 264 DEEEMEEEEGVHGPPVQLAVDDSSDEGELFLKKQEDFEQKYNFRFEEPDSASVKTYPRSI 323
E E EEE G + ++ EGE ++ E+ ++ EE + + +
Sbjct: 962 GEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEV 1021
Query: 324 ASSVRRKD-ERRKEKREETRERKKREKAKKQEELKQLKNLKRKEILAKLEKLRKVTGNEM 382
V ++ E E+ E E ++REK + EE N + +E + E + TG E
Sbjct: 1022 EGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEE-----NRRNREEEEEEEGKYQETGEEE 1076
Query: 383 LGLEEGD 389
++G+
Sbjct: 1077 NERQDGE 1083
Score = 35.4 bits (80), Expect = 0.18
Identities = 22/101 (21%), Positives = 47/101 (46%)
Query: 131 EKAGKYVDEENSDGETSNHRLQETSSQSYVEEQKQLKESFRAFVEDSEDEDGAGEGGSSL 190
E+ G+ EE +GE E + VE + + +E E+ +E+G
Sbjct: 992 EEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGE 1051
Query: 191 LQKRAKTRQEKAQEEADYIEWLKGQKEIRNPDSLKELTHLK 231
++ + R+E+ +EE Y E + + E ++ + K+++ +K
Sbjct: 1052 GEENRRNREEEEEEEGKYQETGEEENERQDGEEYKKVSKIK 1092
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 57.0 bits (136), Expect = 6e-08
Identities = 80/452 (17%), Positives = 198/452 (43%), Gaps = 70/452 (15%)
Query: 13 SSQLRVNAAFAARYNRYREREELQRLKDRYGDRDSSSDSSSESDSSDERVEFDPQQERDF 72
S++L+ +NR +++E + + ++ + + E+ E +QE
Sbjct: 339 SAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKM 398
Query: 73 YKTLSLLKKKDPRIYQKDATFYNRTASSSDSEEDPEALEKQKKVRPMYLKDYERKVILEK 132
+ ++ +K+ ++ +++ + + EE EK++K+R + K +E++ I E+
Sbjct: 399 RRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEE--MMWEKEEKIRELEEKMHEQEKIREQ 456
Query: 133 AGKYVDEENSDGETSNHRLQETSSQSYVEEQKQLKESFRAFVEDSEDEDGAGEGGSSLLQ 192
K +EE + QE ++ + +E+K ++ + + + E++ E +
Sbjct: 457 EEKRQEEEKI---REQEKRQEQEAKMWRQEEKIREQEEK--IREQEEKMWRQE---EKIH 508
Query: 193 KRAKTRQEKAQEEADYIEWLKGQKEIRNPDSLKELTHLKEYWNDPELDEGERFLRDYILN 252
++ K R+E+ ++E + E + +++IR + E W E
Sbjct: 509 EQEKIREEEKRQEQE--EMWRQEEKIREQE---------EIWRQKE-------------- 543
Query: 253 KRYEEEEEEEEDEEEM-EEEEGVHGPPVQLAVDDSSDEGELFLKKQEDFEQKYNFRFEEP 311
K +E+EE+ + EE+M +EE +H ++ E +++ ++++ EQ+ R +E
Sbjct: 544 KIHEQEEKIRKQEEKMWRQEEKMHDQEEKIR----EQEEKVWRQEEKIREQEEKIREQEE 599
Query: 312 DSASVKTYPRSIASSVRRKDERRKEKREETRERKKREKAKKQEELKQLKNLKRKEILAKL 371
R+ E +++EE ++ + +++E++++ + R++
Sbjct: 600 KI---------------REQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIR 644
Query: 372 EKLRKVTGNEMLGLEEGDLEDDFDPAQHDQLMQKCFGDEYYGAVEEEKPQFEEEE-GLED 430
E+ +K+ E E+ ++ + + +Q + C +EEK Q +EE+ ++
Sbjct: 645 EQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMC--------EQEEKMQEQEEKMRRQE 696
Query: 431 DWNWDTWDGPEQEGDWSQQELHCEDPNFNMDA 462
+ W EQE QQE ++ +++A
Sbjct: 697 EKMW------EQEVRLRQQEEKMQEHQEHLEA 722
Score = 55.5 bits (132), Expect = 2e-07
Identities = 111/527 (21%), Positives = 207/527 (39%), Gaps = 97/527 (18%)
Query: 100 SSDSEEDPEALEKQKKVRPMYLKDYERKVILEKAGKYVDEENSDGETSNHRLQETSSQSY 159
+ + E+ A+ QKK Y+++ L K + E ++ L+E +++
Sbjct: 235 AGELEQALSAVATQKKKADRYIEE------LTKERDALSLELYRNTITDEELKEKNAK-- 286
Query: 160 VEEQKQLKESFRAFVEDSEDEDGAGEGGSSLLQKRAKTRQEKAQEEADYIEWLKGQKEIR 219
++E+ QL ES E SE + E L + + Q++ Q EAD++ KE++
Sbjct: 287 LQEKLQLVES-----EKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLG-----KELQ 336
Query: 220 NPDS-LKELTHLKEYWNDPELDEGERFLRDYILNKRYEEEEEEEEDEEEMEEEEGVHGPP 278
+ + L+ E WN + E K + +EE+ +E EE+++E+E
Sbjct: 337 SVSAKLQAQVEENELWNRLNQQQEE---------KMWRQEEKIQEWEEKIQEQE------ 381
Query: 279 VQLAVDDSSDEGELFLKKQEDFEQKYNFRFEEPDSASVKTYPRSIASSVRRKDERRKEKR 338
+ E E +++QE+ +RR++E EK
Sbjct: 382 ------EKIREQEEKIREQEE--------------------------KMRRQEEMMWEKE 409
Query: 339 EETRERK-----KREKAKKQEELKQLKNLKRKEILAKLEKLRKVTGNEMLGLEEGDLEDD 393
E+ R ++ K EK ++QEE+ K K +E+ K+ + K+ E EE + +
Sbjct: 410 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQ 469
Query: 394 FDPAQHDQLM----QKCFGDEYYGAVEEEKPQFEEEEGLEDDWNWDTWDGPEQEGDWSQQ 449
+ + M +K E +EEK +EE+ E + + EQE W Q+
Sbjct: 470 EKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQE 529
Query: 450 ELHCEDPNFNMDADYDPSQPRKKKREAPLTGKKKRKSPFAAAVGQEKPVFEPGDKTFEEY 509
E E + Q K +++ +++ K QE+ + E +K + +
Sbjct: 530 EKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMH-----DQEEKIREQEEKVWRQ- 583
Query: 510 LDEYYRLDYEDIIDDLPCRFKYRTVVPCDFGLSTEEILAADDKELNRWCSLKKTCMYRSE 569
+E R E I + K R EE+ ++++ +K C +
Sbjct: 584 -EEKIREQEEKIREQ---EEKIR---------EQEEMTQEQEEKMGE--QEEKMCEQEEK 628
Query: 570 QEELRDK-RAYSQKAQNSWKKRQVFKSLCREEAETPAEATGKPQRDE 615
+E +K R +K + KK + + RE+ E E K E
Sbjct: 629 MQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQE 675
>gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens]
Length = 2039
Score = 56.6 bits (135), Expect = 8e-08
Identities = 125/618 (20%), Positives = 243/618 (39%), Gaps = 124/618 (20%)
Query: 28 RYREREELQRLKDRYGDRDS--SSDSSSESDSSDERVEFDPQQERDFYKTLSLLKKKDPR 85
+++ERE+ + K+ G+++ + DS+ E S VEFD R+F+K
Sbjct: 633 KHKEREKEKHKKEIEGEKEKYKTKDSAKELQRS---VEFD----REFWKE---------N 676
Query: 86 IYQKDAT---FYNRTASSSDSEEDPEALEKQKKVRPMYLKDYERKVILEKAGKYVDEENS 142
++ D T F N E + LEK+ K+ D K K+V +E +
Sbjct: 677 FFKSDETEDLFLNM-------EHESLTLEKKSKLEKNIKDDKSTKE------KHVSKERN 723
Query: 143 DGETSNHRLQETSSQSYVEEQ-KQLKESFRAFVEDSEDEDGAGEGGSSLLQKRAKTRQEK 201
E + ++++ S +S+ EE+ K LKE R + +D + G S++ + EK
Sbjct: 724 FKEERD-KIKKESEKSFREEKIKDLKEE-RENIPTDKDSEFTSLGMSAIEESIGLHLVEK 781
Query: 202 AQEEADYIEWLKGQKEIRNPDSLKELTHLKEYWNDPELDEGERFLRDYILNKRYEEEEEE 261
I+ K +K I+ KE + + ++++ ER + + K+ + E +
Sbjct: 782 E------IDIEKQEKHIKES---KEKPEKRSQIKEKDIEKMER--KTFEKEKKIKHEHKS 830
Query: 262 EEDE-------EEMEEEEGVHGPPVQLAVDDSSDEGELFLKKQEDFEQKYNFRFEEPDSA 314
E+D+ ++++E++ ++ + + K+ D +K + +
Sbjct: 831 EKDKLDLSECVDKIKEKDKLYSHHTEKCHKEGEKSKNTAAIKKTDDREKSREKMDRKHDK 890
Query: 315 SVKTYPRSIASSVRRKDERRKEKREETRERKKREKAKKQEELKQLKNLKRKEILAKLEKL 374
R +A S + +K K+ + E K EK K +E+ ++L +KE E +
Sbjct: 891 EKPEKERHLAESKEKHLMEKKNKQSDNSEYSKSEKGKNKEKDRELD---KKEKSRDKESI 947
Query: 375 RKVTGNEMLGLEEGDLEDDFDPAQHDQLMQKCFGDEYYGAVEEEKPQFEEEEGLEDDWNW 434
+T ++ + E+ D + AQH EKP +E+ ++
Sbjct: 948 N-ITNSKHIQEEKKSSIVDGNKAQH------------------EKPLSLKEKTKDEPLK- 987
Query: 435 DTWDGPEQEGDWSQQELHCEDPNFNMDADYDPSQPRKK-KREAPLTGKKKRKSPFAAAVG 493
T DG E++ D D D + R K K + + K KS
Sbjct: 988 -TPDGKEKD---------------KKDKDIDRYKERDKHKDKIQINSLLKLKSE----AD 1027
Query: 494 QEKPVFEPGDKTFEEYLDEYYRLDYEDIIDDLPCRFKYRTVVPCDFGLSTEEILAADDKE 553
+ KP P K + + RL +D++ S E +L+ D E
Sbjct: 1028 KPKPKSSPASK---DTRPKEKRLVNDDLMQT-----------------SFERMLSLKDLE 1067
Query: 554 LNRWCSLKKTCMYRSEQEELRDKRAYSQKAQNSWKKRQV-----FKSLCREEAETPAEAT 608
+ +W K + + E+E LR++ K ++ K + K L R ++ +A
Sbjct: 1068 IEQWHKKHKEKIKQKEKERLRNRNCLELKIKDKEKTKHTPTESKNKELTRSKSSEVTDAY 1127
Query: 609 GKPQRDEAGPQRQLPALD 626
K ++ + + ++D
Sbjct: 1128 TKEKQPKDAVSNRSQSVD 1145
Score = 45.8 bits (107), Expect = 1e-04
Identities = 119/668 (17%), Positives = 241/668 (36%), Gaps = 86/668 (12%)
Query: 50 DSSSESDSSDERVEFDPQQERDFYKTLSLLKKKDPRIYQKDATFYNRTASSSDSEEDPEA 109
+ E++ E+ +QE+ FY KK+ P +R SS D EA
Sbjct: 361 EQRKENEPEAEKTHLFAKQEKAFYPKSFKSKKQKP----------SRVLYSSTESSDEEA 410
Query: 110 LEKQKKVRPMYLKDYERKVILEKAGKYVDEENSDGETSNHRLQETSSQSYVEEQKQLKES 169
L+ +K I + NSD +T + + + +++LK
Sbjct: 411 LQNKK--------------ISTSCSVIPETSNSDMQTKKEYVVSGEHKQKGKVKRKLKNQ 456
Query: 170 FRAFVEDSEDEDGAGEGGSSLLQKRAKTR---QEKAQEEADYIEWLKGQKEI-------- 218
+ ++ G+ + + T EK +EE ++ + + +
Sbjct: 457 NKNKENQELKQEKEGKENTRITNLTVNTGLDCSEKTREEGNFRKSFSPKDDTSLHLFHIS 516
Query: 219 --RNPD-----SLKELTHLKEYWNDPELDEGERFLRDYILNKRYEEEEEEEEDEEEM--- 268
++P S K+ T LK+ L G + RY+ E E E
Sbjct: 517 TGKSPKHSCGLSEKQSTPLKQEHTKTCLSPGSSEMSLQPDLVRYDNTESEFLPESSSVKS 576
Query: 269 --EEEEGVHGPPVQLAVDDSSDEGELFLKKQEDFEQKYNFRFEEPDSASVKTYPRSIASS 326
+E+ H L + S+ FE + ++ D +
Sbjct: 577 CKHKEKSKHQKDFHLEFGEKSNAKIKDEDHSPTFENS-DCTLKKMDKEGKTLKKHKLKHK 635
Query: 327 VRRKDERRKEKREETRERKKREKAKKQEELKQLKNLKRKEILAKLEKLRKVTGN---EML 383
R K++ +KE E + K ++ AK+ + + KE K ++ + N E L
Sbjct: 636 EREKEKHKKEIEGEKEKYKTKDSAKELQRSVEFDREFWKENFFKSDETEDLFLNMEHESL 695
Query: 384 GLE-----EGDLEDDFDPAQHDQLMQKCFGDEYYGAVEEEKPQFEEE---EGLEDDWNWD 435
LE E +++DD + ++ F +E +E + F EE + E+ N
Sbjct: 696 TLEKKSKLEKNIKDDKSTKEKHVSKERNFKEERDKIKKESEKSFREEKIKDLKEERENIP 755
Query: 436 TWDGPEQEGDWSQQELHCEDPNFNM---DADYDPSQPRKKKREAPLTGKKKRKSPFAAAV 492
T +++ +++ + + + + + + D + K +E+ +K+ +
Sbjct: 756 T----DKDSEFTSLGMSAIEESIGLHLVEKEIDIEKQEKHIKESKEKPEKRSQIKEKDIE 811
Query: 493 GQEKPVFEPGDKTFEEYLDEYYRLDYEDIIDDLPCRFKYRT--VVPC----DFGLSTEEI 546
E+ FE K E+ E +LD + +D + + K + C + +T I
Sbjct: 812 KMERKTFEKEKKIKHEHKSEKDKLDLSECVDKIKEKDKLYSHHTEKCHKEGEKSKNTAAI 871
Query: 547 LAADDKELNRWCSLKKTCMYRSEQE----ELRDKRAYSQKAQNS----------WKKRQV 592
DD+E +R +K + E+E E ++K +K + S K ++
Sbjct: 872 KKTDDREKSREKMDRKHDKEKPEKERHLAESKEKHLMEKKNKQSDNSEYSKSEKGKNKEK 931
Query: 593 FKSLCREEAETPAEATGKPQRDEAGPQRQLPALDGSLMGPESPPAQEEEAPVSPHKKPAP 652
+ L ++E E+ +++ +DG+ E P + +E+ P K P
Sbjct: 932 DRELDKKEKSRDKESINITNSKHIQEEKKSSIVDGNKAQHEKPLSLKEKTKDEPLKTPDG 991
Query: 653 QKRRRAKK 660
+++ + K
Sbjct: 992 KEKDKKDK 999
Score = 37.0 bits (84), Expect = 0.063
Identities = 64/309 (20%), Positives = 117/309 (37%), Gaps = 36/309 (11%)
Query: 124 YERKVILEKAGKYVDEENSDGETSNHRLQETSSQSYVEEQKQLKESFRAFVEDSEDEDGA 183
Y+ IL AG V+ + D +T H + + V+ L+ F + E
Sbjct: 208 YDVAKILIAAGADVNTQGLDDDTPLHDSASSGHRDIVK--LLLRHGGNPFQANKHGERPV 265
Query: 184 GEGGSSLLQKRAKTRQEKAQEEADYIEWLKGQKEIRNPDSLKELTHLKEYWNDPELDEGE 243
+ L+ K + ++ Y + + Q NP S+ E E D + E +
Sbjct: 266 DVAETEELELLLKREVPLSDDDESYTDSEEAQSV--NPSSVDENID-SETEKDSLICESK 322
Query: 244 RFLRDYI-LNKRYEEEEEEEEDEEE---MEEEEGVHGPPVQLAVDDSSDEGELFLKKQED 299
+ L L +E E +++D+EE M ++ + + + +++ LF K+++
Sbjct: 323 QILPSKTPLPSALDEYEFKDDDDEEINKMIDDRHILRKEQRKENEPEAEKTHLFAKQEKA 382
Query: 300 FEQK-YNFRFEEPD--------------------SASVKTYPRSIASSVRRKDE-----R 333
F K + + ++P S S P + S ++ K E
Sbjct: 383 FYPKSFKSKKQKPSRVLYSSTESSDEEALQNKKISTSCSVIPETSNSDMQTKKEYVVSGE 442
Query: 334 RKEKREETRERKKREKAKKQEELKQLKNLKRKEILAKLEKLRKVTGNEMLGLEEGDLEDD 393
K+K + R+ K + K K+ +ELKQ K K + L + +E EEG+
Sbjct: 443 HKQKGKVKRKLKNQNKNKENQELKQEKEGKENTRITNLTVNTGLDCSEKT-REEGNFRKS 501
Query: 394 FDPAQHDQL 402
F P L
Sbjct: 502 FSPKDDTSL 510
>gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens]
Length = 2062
Score = 56.6 bits (135), Expect = 8e-08
Identities = 125/618 (20%), Positives = 243/618 (39%), Gaps = 124/618 (20%)
Query: 28 RYREREELQRLKDRYGDRDS--SSDSSSESDSSDERVEFDPQQERDFYKTLSLLKKKDPR 85
+++ERE+ + K+ G+++ + DS+ E S VEFD R+F+K
Sbjct: 656 KHKEREKEKHKKEIEGEKEKYKTKDSAKELQRS---VEFD----REFWKE---------N 699
Query: 86 IYQKDAT---FYNRTASSSDSEEDPEALEKQKKVRPMYLKDYERKVILEKAGKYVDEENS 142
++ D T F N E + LEK+ K+ D K K+V +E +
Sbjct: 700 FFKSDETEDLFLNM-------EHESLTLEKKSKLEKNIKDDKSTKE------KHVSKERN 746
Query: 143 DGETSNHRLQETSSQSYVEEQ-KQLKESFRAFVEDSEDEDGAGEGGSSLLQKRAKTRQEK 201
E + ++++ S +S+ EE+ K LKE R + +D + G S++ + EK
Sbjct: 747 FKEERD-KIKKESEKSFREEKIKDLKEE-RENIPTDKDSEFTSLGMSAIEESIGLHLVEK 804
Query: 202 AQEEADYIEWLKGQKEIRNPDSLKELTHLKEYWNDPELDEGERFLRDYILNKRYEEEEEE 261
I+ K +K I+ KE + + ++++ ER + + K+ + E +
Sbjct: 805 E------IDIEKQEKHIKES---KEKPEKRSQIKEKDIEKMER--KTFEKEKKIKHEHKS 853
Query: 262 EEDE-------EEMEEEEGVHGPPVQLAVDDSSDEGELFLKKQEDFEQKYNFRFEEPDSA 314
E+D+ ++++E++ ++ + + K+ D +K + +
Sbjct: 854 EKDKLDLSECVDKIKEKDKLYSHHTEKCHKEGEKSKNTAAIKKTDDREKSREKMDRKHDK 913
Query: 315 SVKTYPRSIASSVRRKDERRKEKREETRERKKREKAKKQEELKQLKNLKRKEILAKLEKL 374
R +A S + +K K+ + E K EK K +E+ ++L +KE E +
Sbjct: 914 EKPEKERHLAESKEKHLMEKKNKQSDNSEYSKSEKGKNKEKDRELD---KKEKSRDKESI 970
Query: 375 RKVTGNEMLGLEEGDLEDDFDPAQHDQLMQKCFGDEYYGAVEEEKPQFEEEEGLEDDWNW 434
+T ++ + E+ D + AQH EKP +E+ ++
Sbjct: 971 N-ITNSKHIQEEKKSSIVDGNKAQH------------------EKPLSLKEKTKDEPLK- 1010
Query: 435 DTWDGPEQEGDWSQQELHCEDPNFNMDADYDPSQPRKK-KREAPLTGKKKRKSPFAAAVG 493
T DG E++ D D D + R K K + + K KS
Sbjct: 1011 -TPDGKEKD---------------KKDKDIDRYKERDKHKDKIQINSLLKLKSE----AD 1050
Query: 494 QEKPVFEPGDKTFEEYLDEYYRLDYEDIIDDLPCRFKYRTVVPCDFGLSTEEILAADDKE 553
+ KP P K + + RL +D++ S E +L+ D E
Sbjct: 1051 KPKPKSSPASK---DTRPKEKRLVNDDLMQT-----------------SFERMLSLKDLE 1090
Query: 554 LNRWCSLKKTCMYRSEQEELRDKRAYSQKAQNSWKKRQV-----FKSLCREEAETPAEAT 608
+ +W K + + E+E LR++ K ++ K + K L R ++ +A
Sbjct: 1091 IEQWHKKHKEKIKQKEKERLRNRNCLELKIKDKEKTKHTPTESKNKELTRSKSSEVTDAY 1150
Query: 609 GKPQRDEAGPQRQLPALD 626
K ++ + + ++D
Sbjct: 1151 TKEKQPKDAVSNRSQSVD 1168
Score = 45.8 bits (107), Expect = 1e-04
Identities = 119/668 (17%), Positives = 241/668 (36%), Gaps = 86/668 (12%)
Query: 50 DSSSESDSSDERVEFDPQQERDFYKTLSLLKKKDPRIYQKDATFYNRTASSSDSEEDPEA 109
+ E++ E+ +QE+ FY KK+ P +R SS D EA
Sbjct: 384 EQRKENEPEAEKTHLFAKQEKAFYPKSFKSKKQKP----------SRVLYSSTESSDEEA 433
Query: 110 LEKQKKVRPMYLKDYERKVILEKAGKYVDEENSDGETSNHRLQETSSQSYVEEQKQLKES 169
L+ +K I + NSD +T + + + +++LK
Sbjct: 434 LQNKK--------------ISTSCSVIPETSNSDMQTKKEYVVSGEHKQKGKVKRKLKNQ 479
Query: 170 FRAFVEDSEDEDGAGEGGSSLLQKRAKTR---QEKAQEEADYIEWLKGQKEI-------- 218
+ ++ G+ + + T EK +EE ++ + + +
Sbjct: 480 NKNKENQELKQEKEGKENTRITNLTVNTGLDCSEKTREEGNFRKSFSPKDDTSLHLFHIS 539
Query: 219 --RNPD-----SLKELTHLKEYWNDPELDEGERFLRDYILNKRYEEEEEEEEDEEEM--- 268
++P S K+ T LK+ L G + RY+ E E E
Sbjct: 540 TGKSPKHSCGLSEKQSTPLKQEHTKTCLSPGSSEMSLQPDLVRYDNTESEFLPESSSVKS 599
Query: 269 --EEEEGVHGPPVQLAVDDSSDEGELFLKKQEDFEQKYNFRFEEPDSASVKTYPRSIASS 326
+E+ H L + S+ FE + ++ D +
Sbjct: 600 CKHKEKSKHQKDFHLEFGEKSNAKIKDEDHSPTFENS-DCTLKKMDKEGKTLKKHKLKHK 658
Query: 327 VRRKDERRKEKREETRERKKREKAKKQEELKQLKNLKRKEILAKLEKLRKVTGN---EML 383
R K++ +KE E + K ++ AK+ + + KE K ++ + N E L
Sbjct: 659 EREKEKHKKEIEGEKEKYKTKDSAKELQRSVEFDREFWKENFFKSDETEDLFLNMEHESL 718
Query: 384 GLE-----EGDLEDDFDPAQHDQLMQKCFGDEYYGAVEEEKPQFEEE---EGLEDDWNWD 435
LE E +++DD + ++ F +E +E + F EE + E+ N
Sbjct: 719 TLEKKSKLEKNIKDDKSTKEKHVSKERNFKEERDKIKKESEKSFREEKIKDLKEERENIP 778
Query: 436 TWDGPEQEGDWSQQELHCEDPNFNM---DADYDPSQPRKKKREAPLTGKKKRKSPFAAAV 492
T +++ +++ + + + + + + D + K +E+ +K+ +
Sbjct: 779 T----DKDSEFTSLGMSAIEESIGLHLVEKEIDIEKQEKHIKESKEKPEKRSQIKEKDIE 834
Query: 493 GQEKPVFEPGDKTFEEYLDEYYRLDYEDIIDDLPCRFKYRT--VVPC----DFGLSTEEI 546
E+ FE K E+ E +LD + +D + + K + C + +T I
Sbjct: 835 KMERKTFEKEKKIKHEHKSEKDKLDLSECVDKIKEKDKLYSHHTEKCHKEGEKSKNTAAI 894
Query: 547 LAADDKELNRWCSLKKTCMYRSEQE----ELRDKRAYSQKAQNS----------WKKRQV 592
DD+E +R +K + E+E E ++K +K + S K ++
Sbjct: 895 KKTDDREKSREKMDRKHDKEKPEKERHLAESKEKHLMEKKNKQSDNSEYSKSEKGKNKEK 954
Query: 593 FKSLCREEAETPAEATGKPQRDEAGPQRQLPALDGSLMGPESPPAQEEEAPVSPHKKPAP 652
+ L ++E E+ +++ +DG+ E P + +E+ P K P
Sbjct: 955 DRELDKKEKSRDKESINITNSKHIQEEKKSSIVDGNKAQHEKPLSLKEKTKDEPLKTPDG 1014
Query: 653 QKRRRAKK 660
+++ + K
Sbjct: 1015 KEKDKKDK 1022
Score = 37.0 bits (84), Expect = 0.063
Identities = 64/309 (20%), Positives = 117/309 (37%), Gaps = 36/309 (11%)
Query: 124 YERKVILEKAGKYVDEENSDGETSNHRLQETSSQSYVEEQKQLKESFRAFVEDSEDEDGA 183
Y+ IL AG V+ + D +T H + + V+ L+ F + E
Sbjct: 231 YDVAKILIAAGADVNTQGLDDDTPLHDSASSGHRDIVK--LLLRHGGNPFQANKHGERPV 288
Query: 184 GEGGSSLLQKRAKTRQEKAQEEADYIEWLKGQKEIRNPDSLKELTHLKEYWNDPELDEGE 243
+ L+ K + ++ Y + + Q NP S+ E E D + E +
Sbjct: 289 DVAETEELELLLKREVPLSDDDESYTDSEEAQSV--NPSSVDENID-SETEKDSLICESK 345
Query: 244 RFLRDYI-LNKRYEEEEEEEEDEEE---MEEEEGVHGPPVQLAVDDSSDEGELFLKKQED 299
+ L L +E E +++D+EE M ++ + + + +++ LF K+++
Sbjct: 346 QILPSKTPLPSALDEYEFKDDDDEEINKMIDDRHILRKEQRKENEPEAEKTHLFAKQEKA 405
Query: 300 FEQK-YNFRFEEPD--------------------SASVKTYPRSIASSVRRKDE-----R 333
F K + + ++P S S P + S ++ K E
Sbjct: 406 FYPKSFKSKKQKPSRVLYSSTESSDEEALQNKKISTSCSVIPETSNSDMQTKKEYVVSGE 465
Query: 334 RKEKREETRERKKREKAKKQEELKQLKNLKRKEILAKLEKLRKVTGNEMLGLEEGDLEDD 393
K+K + R+ K + K K+ +ELKQ K K + L + +E EEG+
Sbjct: 466 HKQKGKVKRKLKNQNKNKENQELKQEKEGKENTRITNLTVNTGLDCSEKT-REEGNFRKS 524
Query: 394 FDPAQHDQL 402
F P L
Sbjct: 525 FSPKDDTSL 533
>gi|56676397 ankyrin repeat domain 11 [Homo sapiens]
Length = 2663
Score = 55.8 bits (133), Expect = 1e-07
Identities = 89/438 (20%), Positives = 170/438 (38%), Gaps = 60/438 (13%)
Query: 30 REREELQRLKDRYGDR-DSSSDSSSESDSSDERVEFDPQQERDFYKTLSLLKKKDPRIYQ 88
+ ++E + + R+G R D S SES+SS+ + +RD + LK +
Sbjct: 457 KRKKETKGREVRFGKRSDKFCSSESESESSESG-----EDDRDSLGSSGCLKGSP--LVL 509
Query: 89 KDATFYNRTASSSDSEEDPEALEKQKKVRPMYLKDYERKVILEKAGKYVDEENSDGETSN 148
KD + ++ ++SS S A +KQ + D+ T N
Sbjct: 510 KDPSLFSSLSASSTSSHGSSAAQKQNP-------------------SHTDQHTKHWRTDN 550
Query: 149 HRLQETSSQSYVEEQKQLKESFRAFVEDSEDEDGAGEGGSSLLQKRAKTRQEKAQEEADY 208
+ T S E L +S R + D G SL R + K ++
Sbjct: 551 WK---TISSPAWSEVSSLSDSTRTRLTSESDYSSEGSSVESLKPVRKRQEHRKRASLSEK 607
Query: 209 IEWLKGQKEIRNPDSLKELTHLKEY---WNDPELDEGERFLRDYILNKRYEEEEEEEEDE 265
E P KE +K++ ++G+ + + K + E E+ + +
Sbjct: 608 KSPFLSSAEGAVPKLDKEGKVVKKHKTKHKHKNKEKGQCSISQELKLKSFTYEYEDSKQK 667
Query: 266 EE----MEEEEGVHGPPVQLAVDDSSDEGELFLKKQEDFEQKYNFRFEEPDSASVKTYPR 321
+ +E + L D + E L K + E+++ F+ +E +K +
Sbjct: 668 SDKAILLENDLSTENKLKVLKHDRDHFKKEEKLSKMKLEEKEWLFK-DEKSLKRIKDTNK 726
Query: 322 SIASSVRRKDERRKEKREETRERKKREKAKKQEEL---KQLKNLKRKEILAKLEKLRKVT 378
I+ S R + +R + +ER +EK+ K+E+L K+ + K K+ +KLEK +
Sbjct: 727 DISRSFREEKDRSNKAE---KERSLKEKSPKEEKLRLYKEERKKKSKDRPSKLEKKNDLK 783
Query: 379 GNEMLGLEEGDLEDDFDPAQHDQLMQKCFG-DEYYGA---VEEEKPQFEEEEGLEDDW-- 432
+++ +E ++D + + +++ ++ DEY +E E +F + D W
Sbjct: 784 EDKISKEKEKIFKEDKEKLKKEKVYREDSAFDEYCNKNQFLENEDTKFSLSDDQRDRWFS 843
Query: 433 ----------NWDTWDGP 440
D+WD P
Sbjct: 844 DLSDSSFDFKGEDSWDSP 861
Score = 52.4 bits (124), Expect = 1e-06
Identities = 116/550 (21%), Positives = 205/550 (37%), Gaps = 110/550 (20%)
Query: 30 REREELQRLKDRYGDRDSSSDSSSESDSSDERVEFDPQQERDFYKTLSLLKKKDPRIYQK 89
+E+ + +R K++ D+D S S E D+ EFD +K K+K + K
Sbjct: 1020 KEKTKPERYKEKSSDKDKSEKSILEKCQKDK--EFDK-----CFKEKKDTKEKHKDTHGK 1072
Query: 90 DATFYNRTASSSDSEEDPEALEKQKKVRPMYLKDYERKVILEKAGK---------YVDEE 140
D R AS +E +K+K + +D+ K +K GK + DE
Sbjct: 1073 DK---ERKASLDQGKE-----KKEKAFPGIISEDFSEKKD-DKKGKEKSWYIADIFTDES 1123
Query: 141 NSDGET---SNHRLQETSSQSYVEEQKQLKESFRAFVED----SEDED------------ 181
D ++ S ++ E S + ++ +E A+ D S D+
Sbjct: 1124 EDDRDSCMGSGFKMGEASDLPRTDGLQEKEEGREAYASDRHRKSSDKQHPERQKDKEPRD 1183
Query: 182 -----GAGEGGSSLLQKRAKTRQEKAQEEADYIEWLKGQKEIRNPDSLKELTHLKEYWND 236
GA + G +K + +EK +E+ E K +K+ + DS ++ + ++
Sbjct: 1184 RRKDRGAADAGRDKKEKVFEKHKEKKDKEST--EKYKDRKDRASVDSTQDKKNKQKL--- 1238
Query: 237 PELDEGERFLRDYILNKRYEEEEEEEEDE--------------EEMEEE------EGVHG 276
PE E + D +K E+ ++E E E++EEE E +
Sbjct: 1239 PEKAEKKHAAEDKAKSKHKEKSDKEHSKERKSSRSADAEKSLLEKLEEEALHEYREDSND 1298
Query: 277 PPVQLAVDDSSDEGELFLKKQEDFEQKYNFRFEEPDSASVKTYPRSIASSVRRKDERR-- 334
+++ D +D G+ + F EP + ++ K+ R
Sbjct: 1299 KISEVSSDSFTDRGQ-----EPGLTAFLEVSFTEPPGDDKPRESACLPEKLKEKERHRHS 1353
Query: 335 --KEKREETRERKKREKAKKQEELKQLKNLKRKEILAKLEK------LRKVTGN------ 380
K+ RER K+EKA+K+E+ + K ++ + EK V+ N
Sbjct: 1354 SSSSKKSHDRERAKKEKAEKKEKGEDYKEGGSRKDSGQYEKDFLEADAYGVSYNMKADIE 1413
Query: 381 -------EMLGLEEGDLED-DFDPAQHDQLMQKCFGDEYYGAVEEEKPQFEEEEGLEDDW 432
E+ E+ D D + +P++ + K +G ++E+K + + E D+
Sbjct: 1414 DELDKTIELFSTEKKDKNDSEREPSKKIEKELKPYGSSAINILKEKKKREKHREKWRDEK 1473
Query: 433 NWDTWDGPEQEGDWSQQEL--HCEDPNFNMDADYDPSQPR----KKKREAPLTGKKKRKS 486
+ + EL H D D D S PR K + E P G K K
Sbjct: 1474 ERHRDRHADGLLRHHRDELLRHHRDEQKPATRDKD-SPPRVLKDKSRDEGPRLGDAKLKE 1532
Query: 487 PFAAAVGQEK 496
F +EK
Sbjct: 1533 KFKDGAEKEK 1542
Score = 48.9 bits (115), Expect = 2e-05
Identities = 113/601 (18%), Positives = 240/601 (39%), Gaps = 78/601 (12%)
Query: 104 EEDPEALEKQKKVRPMYLKDYERKVILEKAGKYVDEENSDGETSNHRLQETSSQSYVE-- 161
+ D + +K++K+ M L++ E EK+ K + + N D S ++ S+++ E
Sbjct: 688 KHDRDHFKKEEKLSKMKLEEKEWLFKDEKSLKRIKDTNKDISRSFREEKDRSNKAEKERS 747
Query: 162 --EQKQLKESFRAFVEDSEDEDGAGEGGSSLLQKRAKTRQEKAQEEADYI-----EWLKG 214
E+ +E R + E+ + + + S L+K+ +++K +E + I E LK
Sbjct: 748 LKEKSPKEEKLRLYKEERKKKS---KDRPSKLEKKNDLKEDKISKEKEKIFKEDKEKLKK 804
Query: 215 QKEIRNPDSLKELTHLKEYWNDPEL------DEGERFLRDYILNKRYEEEEEEEEDEEEM 268
+K R + E + ++ + + D+ +R+ D + + ++ + E+ D
Sbjct: 805 EKVYREDSAFDEYCNKNQFLENEDTKFSLSDDQRDRWFSD-LSDSSFDFKGEDSWDSPVT 863
Query: 269 EEEEGVHGPPVQLAVDDSSDEGE-----------------LFLKKQEDFEQKYNFRFEEP 311
+ + +L ++ ++ + F KK D+ K + + +E
Sbjct: 864 DYRDMKSDSVAKLILETVKEDSKERRRDSRAREKRDYREPFFRKKDRDYLDKNSEKRKEQ 923
Query: 312 DSASVKTYPRSIASSVRRKDERRKEKREETRERKKREKAKKQEELKQLKNLKRKEILAKL 371
+S+ + KD++R+E E R+RK E K+ ++ + K A
Sbjct: 924 TEKH-----KSVPGYLSEKDKKRRESAEAGRDRK-----DALESCKERRDGRAKPEEAHR 973
Query: 372 EKLRKV-TGNEMLGLEEGDLEDDFDP-AQHDQLMQKCFGDEYYGAVEEEKPQFEEEEGLE 429
E+L++ + +GD +P +H +K ++ G +E K + + E E
Sbjct: 974 EELKECGCESGFKDKSDGDFGKGLEPWERHHPAREK---EKKDGPDKERKEKTKPERYKE 1030
Query: 430 DDWNWDTWDGPEQEGDWSQQEL-HCEDPNFNMDADYDPSQPRKKKREAPL-TGKKKRKSP 487
+ D + E +E C + + + + K+R+A L GK+K++
Sbjct: 1031 KSSDKDKSEKSILEKCQKDKEFDKCFKEKKDTKEKHKDTHGKDKERKASLDQGKEKKEKA 1090
Query: 488 FAAAVGQEKPVFEPGDKTFEE--YLDEYYRLDYEDIIDD-LPCRFKY--RTVVPCDFGLS 542
F + ++ + K E+ Y+ + + + ED D + FK + +P GL
Sbjct: 1091 FPGIISEDFSEKKDDKKGKEKSWYIADIFTDESEDDRDSCMGSGFKMGEASDLPRTDGLQ 1150
Query: 543 TEE---ILAADDKELNRWCSLKKTCMYRSEQEELRDKRAYSQKAQ-NSWKKRQVFKSLCR 598
+E A D+ S K R + +E RD+R A KK +VF+
Sbjct: 1151 EKEEGREAYASDRHRK---SSDKQHPERQKDKEPRDRRKDRGAADAGRDKKEKVFEK--- 1204
Query: 599 EEAETPAEATGKPQRDEAGPQRQLPALDGSLMGPESPPAQEEEAPVSPHKKPAPQKRRRA 658
K ++D+ ++ D + + +++ P KK A + + ++
Sbjct: 1205 ----------HKEKKDKESTEKYKDRKDRASVDSTQDKKNKQKLPEKAEKKHAAEDKAKS 1254
Query: 659 K 659
K
Sbjct: 1255 K 1255
Score = 33.1 bits (74), Expect = 0.91
Identities = 75/411 (18%), Positives = 149/411 (36%), Gaps = 50/411 (12%)
Query: 124 YERKVILEKAGKYVDEENSDGETSNHRLQETSSQSYVEEQKQLKESFRAFVEDSEDEDGA 183
Y+ +L + G + N GET + + + + S + E SE+ED
Sbjct: 247 YKVVKLLLRYGGNPQQSNRKGETPLKVANSPTMVNLLLGKGTYTSSEESSTESSEEEDAP 306
Query: 184 GEGGSSLLQKRAKTRQEKAQEEADYIEWLKGQKEIRNPDSLKELTHLKEYWNDPELDEGE 243
SS + ++++ + LK + +NP+ K +K+ + E DE +
Sbjct: 307 SFAPSSSVDGN--------NTDSEFEKGLK--HKAKNPEPQKATAPVKDEYEFDEDDEQD 356
Query: 244 RFLR---DYILNKRYEEEEEEEEDEEEMEEEEGVHGPPVQLAVDDSSDEGELFLKKQEDF 300
R ++L K Y +E + + P +++ S + K+
Sbjct: 357 RVPPVDDKHLLKKDYRKETKSNSF---------ISIPKMEVK---SYTKNNTIAPKKASH 404
Query: 301 EQKYNFRFEEPDSASVKTYPRS-------IASSVRRKDERRKEKREETRERKKREKAKKQ 353
+ EE S +V T + + S R+ K+++E+ + +KKR+K K
Sbjct: 405 RILSDTSDEEDASVTVGTGEKLRLSAHTILPGSKTREPSNAKQQKEKNKVKKKRKKETKG 464
Query: 354 EELKQLKNLKRKEILAKLEKLRKVTGNE------MLGLEEGDLEDDFDPAQHDQLMQKCF 407
E++ K K ++ E +G + G +G DP+ L
Sbjct: 465 REVRFGKR-SDKFCSSESESESSESGEDDRDSLGSSGCLKGSPLVLKDPSLFSSLSASST 523
Query: 408 GDEYYGAVEEEKPQFEEEEGLEDDW---NWDT-----WDGPEQEGDWSQQELHCEDPNFN 459
A +++ P ++ W NW T W D ++ L E +
Sbjct: 524 SSHGSSAAQKQNPSHTDQH--TKHWRTDNWKTISSPAWSEVSSLSDSTRTRLTSESDYSS 581
Query: 460 MDADYDPSQP-RKKKREAPLTGKKKRKSPFAAAVGQEKPVFEPGDKTFEEY 509
+ + +P RK++ ++KSPF ++ P + K +++
Sbjct: 582 EGSSVESLKPVRKRQEHRKRASLSEKKSPFLSSAEGAVPKLDKEGKVVKKH 632
>gi|15149465 caldesmon 1 isoform 5 [Homo sapiens]
Length = 532
Score = 55.8 bits (133), Expect = 1e-07
Identities = 83/376 (22%), Positives = 152/376 (40%), Gaps = 75/376 (19%)
Query: 101 SDSEEDPEALEKQKKVRPMYLKDYERKVILEKAGKYVD--EENSDGETSNHRLQETSSQS 158
+D +E+ A E++++ R L+ + + E G+ D E N+ + + T++ +
Sbjct: 24 NDDDEEEAARERRRRARQERLRQKQEE---ESLGQVTDQVEVNAQNSVPDEEAKTTTTNT 80
Query: 159 YVEEQKQLKESFRAFVEDSEDEDGAGEGGSSLLQKRAKTRQEKAQEEADYIEWLKG---- 214
VE +DE E + ++R K QE + + ++ +
Sbjct: 81 QVE---------------GDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLS 125
Query: 215 --QKEIRNPDSLKELTHLKEYWNDP----ELDEGERFLRDYILNKRYEEEEEEEEDEEEM 268
+ ++N + E T +E E++E E + Y N + EE ++ED+E+
Sbjct: 126 LPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKE 185
Query: 269 EEEEGVHGPPVQLAVDDSSDEGELFLKKQEDFEQKYNF---------------------- 306
EEEE P + ++ ++ + E K +E E+ +F
Sbjct: 186 EEEE---EKPKRGSIGENQIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKL 242
Query: 307 -----RFEEPDS-ASVKTYPRSIASSV---RRKDERRKEKREETRERKKREKAKKQEELK 357
F P ASV T A V +R +E R+ + E E ++ K K+QE
Sbjct: 243 KHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAAL 302
Query: 358 QLKNLKRKEILAKLEKLRKVTGNEMLGLEEGDLEDDFDPAQHDQLMQKCFGDEY--YGAV 415
+L+ LK+K E+ RKV E E+ +++ D ++ ++ +E A
Sbjct: 303 ELEELKKKR-----EERRKVLEEE----EQRRKQEEADRKLREEEEKRRLKEEIERRRAE 353
Query: 416 EEEKPQFEEEEGLEDD 431
EK Q E+GL DD
Sbjct: 354 AAEKRQKMPEDGLSDD 369
Score = 35.8 bits (81), Expect = 0.14
Identities = 30/146 (20%), Positives = 62/146 (42%), Gaps = 8/146 (5%)
Query: 223 SLKELTHLKEYWNDPELDEGERFLRDYILNKRYEEEEEEEE-----DEEEMEEEEGVHGP 277
SL L+ + ND + +E R R +R +++EEE D+ E+ + V
Sbjct: 12 SLAALSQIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDE 71
Query: 278 PVQLAVDDSSDEGE---LFLKKQEDFEQKYNFRFEEPDSASVKTYPRSIASSVRRKDERR 334
+ ++ EG+ FL++ E++ R +E + P +S+ R
Sbjct: 72 EAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRM 131
Query: 335 KEKREETRERKKREKAKKQEELKQLK 360
+ E +K EK++ ++E +++
Sbjct: 132 QNDTAENETTEKEEKSESRQERYEIE 157
>gi|4826657 caldesmon 1 isoform 2 [Homo sapiens]
Length = 538
Score = 55.8 bits (133), Expect = 1e-07
Identities = 83/376 (22%), Positives = 152/376 (40%), Gaps = 75/376 (19%)
Query: 101 SDSEEDPEALEKQKKVRPMYLKDYERKVILEKAGKYVD--EENSDGETSNHRLQETSSQS 158
+D +E+ A E++++ R L+ + + E G+ D E N+ + + T++ +
Sbjct: 30 NDDDEEEAARERRRRARQERLRQKQEE---ESLGQVTDQVEVNAQNSVPDEEAKTTTTNT 86
Query: 159 YVEEQKQLKESFRAFVEDSEDEDGAGEGGSSLLQKRAKTRQEKAQEEADYIEWLKG---- 214
VE +DE E + ++R K QE + + ++ +
Sbjct: 87 QVE---------------GDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLS 131
Query: 215 --QKEIRNPDSLKELTHLKEYWNDP----ELDEGERFLRDYILNKRYEEEEEEEEDEEEM 268
+ ++N + E T +E E++E E + Y N + EE ++ED+E+
Sbjct: 132 LPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKE 191
Query: 269 EEEEGVHGPPVQLAVDDSSDEGELFLKKQEDFEQKYNF---------------------- 306
EEEE P + ++ ++ + E K +E E+ +F
Sbjct: 192 EEEE---EKPKRGSIGENQIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKL 248
Query: 307 -----RFEEPDS-ASVKTYPRSIASSV---RRKDERRKEKREETRERKKREKAKKQEELK 357
F P ASV T A V +R +E R+ + E E ++ K K+QE
Sbjct: 249 KHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAAL 308
Query: 358 QLKNLKRKEILAKLEKLRKVTGNEMLGLEEGDLEDDFDPAQHDQLMQKCFGDEY--YGAV 415
+L+ LK+K E+ RKV E E+ +++ D ++ ++ +E A
Sbjct: 309 ELEELKKKR-----EERRKVLEEE----EQRRKQEEADRKLREEEEKRRLKEEIERRRAE 359
Query: 416 EEEKPQFEEEEGLEDD 431
EK Q E+GL DD
Sbjct: 360 AAEKRQKMPEDGLSDD 375
>gi|31982906 cingulin-like 1 [Homo sapiens]
Length = 1302
Score = 55.8 bits (133), Expect = 1e-07
Identities = 99/471 (21%), Positives = 187/471 (39%), Gaps = 73/471 (15%)
Query: 7 MPEPRGSSQLRVNAAFAARYNRYREREELQRLKDRYGDRDSSSDSSSESDSSDE--RVEF 64
+ E G + + F + R + + E++ L+D+ + DS+ S+ ++ +E
Sbjct: 672 LEESEGELRKNLEELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAKRSEDREKGALIEE 731
Query: 65 DPQQERDFYKTLSLLKKKDP--RIYQKDATFYNRTASSSDSEEDPEALEKQKKVRPMYLK 122
Q ++D L ++++ R +++ T S D E K++ Y
Sbjct: 732 LLQAKQDLQDLLIAKEEQEDLLRKRERELTALKGALKEEVSSHDQE----MDKLKEQY-- 785
Query: 123 DYERKVILEKAGKYVDEENSDGETSNHRLQETSSQSYVEEQKQLKESFRAFVEDSEDEDG 182
D E + + E E + ++ +S+S EQ Q R + E+E
Sbjct: 786 DAELQALRESV-----------EEATKNVEVLASRSNTSEQDQAGTEMRVKLLQEENEK- 833
Query: 183 AGEGGSSLLQKRAKTRQEKAQEEADYIEWLKGQKEIRNPDSLKELTHLKEYWNDPELDEG 242
LQ R++ + + + IE LKG D K LK+Y EG
Sbjct: 834 --------LQGRSEELERRVAQLQRQIEDLKG-------DEAKAKETLKKY-------EG 871
Query: 243 E-RFLRDYILNKRYEEEEEEEEDEEEMEEEEGVHGPPVQLAVDDSSDEGELFLKKQEDFE 301
E R L + +++ R EE+E E E G Q + ++ +L K +E+ E
Sbjct: 872 EIRQLEEALVHARKEEKEAVSARRALENELEAAQGNLSQ----TTQEQKQLSEKLKEESE 927
Query: 302 QKYNFRFEEPDSASVKTY-----------PRSIASSVRRKDERRKEKREETRERKKREKA 350
QK R + + + + + I + R + + +E +E+ +RE A
Sbjct: 928 QKEQLRRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTLELQNQLDEYKEKNRRELA 987
Query: 351 KKQEELKQLKNLKRKEILAKLEKLRKVTGNEMLGLEEGDLEDDFDPAQHDQLMQKCFGDE 410
+ Q +LK+ K + A+ +L + + + L E +L D+ AQ + L ++ ++
Sbjct: 988 EMQRQLKE------KTLEAEKSRLTAMKMQDEMRLMEEELR-DYQRAQDEALTKRQLLEQ 1040
Query: 411 YYGAVEEEKPQFEEEEGLEDDWNWDTWDGPEQEGDWSQQELHCEDPNFNMD 461
+E E E + L+DD + + E SQ E+ E+ N D
Sbjct: 1041 TLKDLEYE---LEAKSHLKDDRSRLV---KQMEDKVSQLEMELEEERNNSD 1085
Score = 35.0 bits (79), Expect = 0.24
Identities = 46/234 (19%), Positives = 95/234 (40%), Gaps = 13/234 (5%)
Query: 45 RDSSSDSSSESDSSDERVEFDPQQERDFYKTLS-LLKKKDPRIYQKDATFYNRTASSSDS 103
+D S + + ++E + ++ER+ LS + + ++ Q A+ D
Sbjct: 1056 KDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERISRSREQMEQLRNELLQERAARQDL 1115
Query: 104 EEDPEALEKQKKVRPMYLKDYERKVILEKAGKYVDEENSDGETSNHRLQETSSQSYVE-E 162
E D +LE+Q K + E K G V E E + E ++ ++
Sbjct: 1116 ECDKISLERQNKDLKSRIIHLEGSYRSSKEGLVVQMEARIAELEDRLESEERDRANLQLS 1175
Query: 163 QKQLKESFRAFVEDSEDEDGA---GEGGSSLLQKRAKTRQEKAQEEADYIEWLKGQKEIR 219
++L+ + V +DE + + SL K K + E+A+EE D +E K + +
Sbjct: 1176 NRRLERKVKELVMQVDDEHLSLTDQKDQLSLRLKAMKRQVEEAEEEIDRLESSKKKLQRE 1235
Query: 220 NPDSLKELTHLKEYWNDPELDEGERFLRDYILNKRYEEEEEEEEDEEEMEEEEG 273
+ + HL+ N + +D L K + ++ +D++++ + G
Sbjct: 1236 LEEQMDMNEHLQGQLNSMK--------KDLRLKKLPSKVLDDMDDDDDLSTDGG 1281
>gi|148839339 nexilin (F actin binding protein) [Homo sapiens]
Length = 675
Score = 55.8 bits (133), Expect = 1e-07
Identities = 82/384 (21%), Positives = 158/384 (41%), Gaps = 61/384 (15%)
Query: 38 LKDRYGDRDSSSDSSSESDSSDER---VEFDPQQERDFYKTLSLLKKKDPRIYQKDATFY 94
+K R+ + + + +ER +E D ++R + L+ ++ I
Sbjct: 102 VKGRFAEMEKQRQEEQRKRTEEERKRRIEQDMLEKRKIQRELAKRAEQIEDI-------- 153
Query: 95 NRTASSSDSEEDPEALEKQKKVRPMYLKDYERKVILEKAGKYVDEENSDGETSNHRLQET 154
N T + S SEE ++L + + +K Y+ ++K + D E E + +E
Sbjct: 154 NNTGTESASEEGDDSL----LITVVPVKSYKTSGKMKK--NFEDLEKEREEKERIKYEED 207
Query: 155 SSQSYVEEQKQLKES-FRAFVEDSEDEDGAGEGGSS----------LLQKRAKTRQEKAQ 203
Y E++ LKE+ + V D E E A + S L ++R + R+++A+
Sbjct: 208 KRIRYEEQRPSLKEAKCLSLVMDDEIESEAKKESLSPGKLKLTFEELERQRQENRKKQAE 267
Query: 204 EEADYIEWLKGQKEIRNPDSLKELTHLKEYWNDPELDEGERFLRDYILNK---------R 254
EEA +K + E + D E + + + Y K R
Sbjct: 268 EEA--------RKRLEEEKRAFEEARRQMVNEDEENQDTAKIFKGYRPGKLKLSFEEMER 319
Query: 255 YEEEEEEEEDEEEM-----EEEEGVHGPPVQLAVDDSSDE-----GELFL---KKQEDFE 301
E+E+ + EEE EE++ + VDD S E + FL K + +FE
Sbjct: 320 QRREDEKRKAEEEARRRIEEEKKAFAEARRNMVVDDDSPEMYKTISQEFLTPGKLEINFE 379
Query: 302 QKYNFRFEEPDSASVKTYPRSIASSVRRKDERRKEKREETRERKKREKAKKQEELKQLK- 360
+ + EE + + + + ++ R+E EE E + +++ EEL +LK
Sbjct: 380 ELLKQKMEEEKRRTEEERKHKLEMEKQEFEQLRQEMGEEEEENETFGLSREYEELIKLKR 439
Query: 361 --NLKRKEILAKLEKLRKVTGNEM 382
+++ K + +K EK+ +++ E+
Sbjct: 440 SGSIQAKNLKSKFEKIGQLSEKEI 463
Score = 39.7 bits (91), Expect = 0.010
Identities = 74/345 (21%), Positives = 140/345 (40%), Gaps = 49/345 (14%)
Query: 254 RYEEEEEEEEDEEEMEEEEGVHGPPVQLAVDDSSDEGELFLKKQEDFEQKYNFRFEEPDS 313
R E + DE++ +E+ + E E +KQE E + E+ S
Sbjct: 42 REERNQRRSRDEKQRRKEQYIR-------------EREWNRRKQEIKEMLASDDEEDVSS 88
Query: 314 ASVKTYPRSIASSVRRKDERRKEKREETRERKKREKAKKQEELKQLKNLK-RKEILAKLE 372
K Y + +V+ + +++R+E + ++ E+ K++ E L+ K ++E+ + E
Sbjct: 89 KVEKAYVPKLTGTVKGRFAEMEKQRQEEQRKRTEEERKRRIEQDMLEKRKIQRELAKRAE 148
Query: 373 KLRKV--TGNEMLGLEEGD--LEDDFDPAQHDQL---MQKCFGDEYYGAVEEEKPQFEEE 425
++ + TG E EEGD L P + + M+K F D E+E+ ++EE+
Sbjct: 149 QIEDINNTGTESAS-EEGDDSLLITVVPVKSYKTSGKMKKNFEDLEKEREEKERIKYEED 207
Query: 426 EGLEDDWNWDTWDGPEQEGDWSQQELHC----EDPNFNMDADYDPSQPRKKKREAPLTGK 481
+ + +E S +E C D +A + P K K +
Sbjct: 208 KRIR-----------YEEQRPSLKEAKCLSLVMDDEIESEAKKESLSPGKLKLTFEELER 256
Query: 482 KKRKSPFAAAVGQEKPVFEPGDKTFEEYLDEYYRLDYEDIIDDLPCRFK-YRTVVPCDFG 540
+++++ A + + E + FEE + D E+ D FK YR P
Sbjct: 257 QRQENRKKQAEEEARKRLEEEKRAFEEARRQMVNEDEEN--QDTAKIFKGYR---PGKLK 311
Query: 541 LSTEEILAADDKELNRWCSLKKTCMYRSEQEELRDKRAYSQKAQN 585
LS EE+ E R K+ + + +K+A+++ +N
Sbjct: 312 LSFEEM------ERQRREDEKRKAEEEARRRIEEEKKAFAEARRN 350
Score = 39.3 bits (90), Expect = 0.013
Identities = 81/397 (20%), Positives = 160/397 (40%), Gaps = 50/397 (12%)
Query: 30 REREELQRLKD------RYGD-RDSSSDSSSESDSSDERVEFDPQQERDFYKTLSLLKKK 82
+EREE +R+K RY + R S ++ S D+ +E + ++E L L ++
Sbjct: 194 KEREEKERIKYEEDKRIRYEEQRPSLKEAKCLSLVMDDEIESEAKKESLSPGKLKLTFEE 253
Query: 83 DPRIYQKDATFYNRTASSSDSEEDPEALEKQKKVRPMYLKDYERKVILE-----KAGK-- 135
R Q++ + EE+ A E+ + R M +D E + + + GK
Sbjct: 254 LERQRQENRKKQAEEEARKRLEEEKRAFEEAR--RQMVNEDEENQDTAKIFKGYRPGKLK 311
Query: 136 --YVDEENSDGETSNHRLQETSSQSYVEEQKQLKESFRAFVEDSEDEDGAGEGGSSLLQK 193
+ + E E + +E + + EE+K E+ R V D + + + +
Sbjct: 312 LSFEEMERQRREDEKRKAEEEARRRIEEEKKAFAEARRNMVVDDDSPE--------MYKT 363
Query: 194 RAKTRQEKAQEEADYIEWLKGQKEIRNPDSLKELTHLKEYWNDP------ELDEGERFLR 247
++ + E ++ E LK + E + +E H E E+ E E
Sbjct: 364 ISQEFLTPGKLEINFEELLKQKMEEEKRRTEEERKHKLEMEKQEFEQLRQEMGEEEEENE 423
Query: 248 DYILNKRYEE--------EEEEEEDEEEMEEEEGVHGPPVQLAVDDSSDEGELFLKKQED 299
+ L++ YEE + + + + E+ + +Q +++ E ++ D
Sbjct: 424 TFGLSREYEELIKLKRSGSIQAKNLKSKFEKIGQLSEKEIQKKIEE-----ERARRRAID 478
Query: 300 FEQKYNF--RFEEPDSASVKTYPRSIASSVRRKDERRKEKREETRERKKREKAKKQEELK 357
E K F E D V+ +S A + + K + E+ + ++ E+ ++ EE K
Sbjct: 479 LEIKEREAENFHEEDDVDVRPARKSEAPFTHKVN--MKARFEQMAKAREEEEQRRIEEQK 536
Query: 358 QLK-NLKRKEILAKLEKLRKVTGNEMLGLEEGDLEDD 393
L+ +++EI A L+K R+ E + G +D
Sbjct: 537 LLRMQFEQREIDAALQKKREEEEEEEGSIMNGSTAED 573
Score = 31.6 bits (70), Expect = 2.7
Identities = 34/157 (21%), Positives = 64/157 (40%), Gaps = 20/157 (12%)
Query: 122 KDYERKVILEKAGKYVDEENSDGETSNHRLQETSSQSYVEEQKQLKESFRAFVEDSEDED 181
++YE + L+++G + +L E Q +EE++ + + +++ E E+
Sbjct: 429 REYEELIKLKRSGSIQAKNLKSKFEKIGQLSEKEIQKKIEEERARRRAIDLEIKEREAEN 488
Query: 182 GAGEGGSSLLQKRAKTRQ--EKAQEEADYIEWLKGQKEIRNPDSLKELTHLKEYWNDPEL 239
E + R K +A + + K ++E ++E L+ + E+
Sbjct: 489 FHEEDDVDVRPARKSEAPFTHKVNMKARFEQMAKAREE-EEQRRIEEQKLLRMQFEQREI 547
Query: 240 DEGERFLRDYILNKRYEEEEEEE---------EDEEE 267
D L K+ EEEEEEE EDEE+
Sbjct: 548 DAA--------LQKKREEEEEEEGSIMNGSTAEDEEQ 576
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 55.5 bits (132), Expect = 2e-07
Identities = 62/256 (24%), Positives = 106/256 (41%), Gaps = 49/256 (19%)
Query: 121 LKDYERKVILEKAGKYVDEENSDGETSNHRLQETSSQSYVEEQKQLKESFRAFVEDSEDE 180
+++ ER++ K GK +E R +E + +E+K+ + E ++E
Sbjct: 38 IREREREIETRKEGK---KERESERKKERREREKRKREREKERKRERGKKEKKGERKKEE 94
Query: 181 DGAGEGGSSLLQKRAKTRQEKAQEEADYIEWLKGQKEIRNPDSLKELTHLKEYWNDPELD 240
++R K R+EK +E + +KE R KE + + E
Sbjct: 95 -----------RERKKRRREKENKEGE-------EKEKRKKKEKKERGRTSKEGKERERK 136
Query: 241 EGERFLRDYILNKRYEEEEEEEEDEEEMEEEEGVHGPPVQLAVDDSSDEGELFLKKQEDF 300
E + +R E E ++EE E+E E +E Q+ E E K++E
Sbjct: 137 EERK------REERKERERKKEEREKERERKERKKRERKQVG------EKEEERKEKERK 184
Query: 301 EQKYNFRFEEPDSASVKTYPRSIASSVRRKDERRKEKREETRERKKREKAKKQEELKQLK 360
E+K R + R+K+ RKE+RE +ERKK+E+ KK+ + +
Sbjct: 185 ERKKRERNRKE----------------RKKERERKERRERKKERKKKEERKKERQKDRQT 228
Query: 361 NLKRKEILAKLEKLRK 376
N + KE + K RK
Sbjct: 229 NWREKERGKRERKERK 244
Score = 46.2 bits (108), Expect = 1e-04
Identities = 45/200 (22%), Positives = 90/200 (45%), Gaps = 19/200 (9%)
Query: 192 QKRAKTRQEKAQEEADYIEWLKGQKEIRNPDSLKELTH---LKEYWNDPELDEGERFLRD 248
++ +TR+E +E + + ++E R + KE KE + + +E ER R
Sbjct: 42 EREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKR- 100
Query: 249 YILNKRYEEEEEEEEDEEEMEEEEGVHGPPVQLAVDDSSDEGELFLKKQEDFEQKYNFRF 308
+R +E +E EE E+ ++E+ G + + E +K+E+ +++ +
Sbjct: 101 ----RREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEE----RKREERKERERKKE 152
Query: 309 EEPDSASVKTYPRSIASSVRRKDERRKEK-------REETRERKKREKAKKQEELKQLKN 361
E K + V K+E RKEK RE R+ +K+E+ +K+ ++ +
Sbjct: 153 EREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKER 212
Query: 362 LKRKEILAKLEKLRKVTGNE 381
K++E + +K R+ E
Sbjct: 213 KKKEERKKERQKDRQTNWRE 232
Score = 38.5 bits (88), Expect = 0.022
Identities = 34/172 (19%), Positives = 76/172 (44%), Gaps = 10/172 (5%)
Query: 314 ASVKTYPRSIASSVRRKDERRKEKREETRERKKREKAKKQEELKQLKNLKRKEILAKLEK 373
+ ++ R I + K ER E+++E RER+KR++ +++E ++ ++K K E+
Sbjct: 36 SEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEER 95
Query: 374 LRKVTGNEMLGLEEGDLEDDFDPAQHDQLMQKCFGDEYYGAVEEEKPQFEEEEGLEDDWN 433
RK E E + E + ++ G E E ++ + +E E ++
Sbjct: 96 ERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKE--- 152
Query: 434 WDTWDGPEQEGDWSQQELHCEDPNFNMDADYDPSQPRKKKREAPLTGKKKRK 485
E+E + ++E + + + + + +K+R+ +K+RK
Sbjct: 153 -------EREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERK 197
Score = 34.3 bits (77), Expect = 0.41
Identities = 48/217 (22%), Positives = 98/217 (45%), Gaps = 19/217 (8%)
Query: 30 RERE-ELQRLKDRYGDRDSSSDSSSESDSSDERV-EFDPQQERDFYKTLSLLKKKDPRIY 87
RERE E++ K+ G ++ S+ E ++R E + +++R+ K KK + +
Sbjct: 39 REREREIETRKE--GKKERESERKKERREREKRKREREKERKRERGKKE---KKGERKKE 93
Query: 88 QKDATFYNRTASSSDSEEDPEALEKQKKVRPMYLKDYERKVILEKAGKYVDEENSDGETS 147
+++ R + + EE + +K+KK R K+ + + E+ + EE + E
Sbjct: 94 ERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKER---ERKEERKREERKERERK 150
Query: 148 NHRLQETSSQSYVEEQKQLKESFRAFVEDSEDEDGAGEGGSSLLQKRAKTRQEKAQEEAD 207
++ E+K+ K+ R V + E+E E +KR + R+E+ ++E +
Sbjct: 151 KEEREKE------RERKERKKRERKQVGEKEEERKEKERKER--KKRERNRKER-KKERE 201
Query: 208 YIEWLKGQKEIRNPDSLKELTHLKEYWNDPELDEGER 244
E + +KE + + K+ N E + G+R
Sbjct: 202 RKERRERKKERKKKEERKKERQKDRQTNWREKERGKR 238
Score = 30.0 bits (66), Expect = 7.7
Identities = 25/147 (17%), Positives = 60/147 (40%)
Query: 25 RYNRYREREELQRLKDRYGDRDSSSDSSSESDSSDERVEFDPQQERDFYKTLSLLKKKDP 84
R RERE+ +R +++ R+ +ER ++E++ + K+K
Sbjct: 59 RKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKK 118
Query: 85 RIYQKDATFYNRTASSSDSEEDPEALEKQKKVRPMYLKDYERKVILEKAGKYVDEENSDG 144
++ T E E +++++ + K+ ERK ++ K V E+ +
Sbjct: 119 EKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEER 178
Query: 145 ETSNHRLQETSSQSYVEEQKQLKESFR 171
+ + ++ ++ E +K+ + R
Sbjct: 179 KEKERKERKKRERNRKERKKERERKER 205
>gi|90819237 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 4 isoform 1 [Homo
sapiens]
Length = 1834
Score = 55.1 bits (131), Expect = 2e-07
Identities = 81/364 (22%), Positives = 142/364 (39%), Gaps = 41/364 (11%)
Query: 313 SASVKTYPRSIASSVRRKDERRKEKREETRERKKREKAKKQEELKQLKNLKRKEILAKLE 372
SA V R +R E+ K + EE RERK+RE+ +K +++ ++L
Sbjct: 1400 SAQVAAAERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMR-TQSLNPAPFSPLTA 1458
Query: 373 KLRKVTGNEMLGLEEGDLEDDFDPAQHDQLMQKCFGDEYYGAVEEEKPQFEEEEGLEDDW 432
+ K L + + + P Q + +++ D Y V +EE D
Sbjct: 1459 QQMKPEKPSTLQRPQETVIRELQPQQQPRTIER--RDLQYITVS------KEELSSGDSL 1510
Query: 433 NWDTWDGPEQEGDWSQQELHCEDPNFNMDADYDPSQPRKKKREAPLTGKKKRKSPFAAAV 492
+ D W +E QQ++H D + + S+P + E+ K + F +
Sbjct: 1511 SPDPWKRDAKEKLEKQQQMHIVD-MLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRL 1569
Query: 493 GQEKPVFEPGDKTFEEYLDEYYRLDYEDIIDDLPCRFKYRTVVPCDFGLSTEEILAADDK 552
+ K E ++ ++ +D I+ L + RT +P +S ++L D+
Sbjct: 1570 QESKQKDEDDEEEEDDDVDTML------IMQRLEAERRARTAMP---AISVLDLL--QDE 1618
Query: 553 ELNRWCSLKKTCMYRSEQEELRDKRAYSQKAQNSWKKRQVFKSLCREEAETPAEATGKPQ 612
E R + + EE+R + A + Q ++RQ + R+ E + G
Sbjct: 1619 ERRR----------QQQLEEMRKREAEDRARQEEERRRQEEERTKRDAEEKRRQEEGYYS 1668
Query: 613 RDEAGPQRQLPALDGSLMGPES-----PPAQEEEAPVSPHKKPA-----PQKRRRAKKAR 662
R EA +RQ L+ PE+ PP + P SP P PQ+ K +
Sbjct: 1669 RLEAERRRQHDEAARRLLEPEAPGLCRPPLPRDYEPPSPSPAPGAPPPPPQRNASYLKTQ 1728
Query: 663 LLGP 666
+L P
Sbjct: 1729 VLSP 1732
Score = 43.1 bits (100), Expect = 9e-04
Identities = 58/311 (18%), Positives = 135/311 (43%), Gaps = 30/311 (9%)
Query: 93 FYNRTASSSDSEEDPEALEKQKKVRPMYLKDYERKVILEKAGKYVDEENSDGETSNHRLQ 152
+Y + + + E + + E+++K+ M + + + E ++ R Q
Sbjct: 1417 WYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKP---STLQRPQ 1473
Query: 153 ETSSQSYVEEQ--KQLKESFRAFVEDSEDEDGAGEGGSSLLQKRAKTRQEKAQEEADYIE 210
ET + +Q + ++ ++ S++E +G+ S KR + + Q++ ++
Sbjct: 1474 ETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEKQQQMHIVD 1533
Query: 211 WLKGQKEIRNPDSLKELTHLKEYWNDPELDEGERFLRDYILNKRYEEEEEEEEDEEEMEE 270
L KEI+ S K + E D + + ++ KR +E ++++ED+EE EE
Sbjct: 1534 MLS--KEIQELQS-------KPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEE-EE 1583
Query: 271 EEGVHGPPVQLAVD-----DSSDEGELFLKKQEDFEQKYNFRFEEPDSASVKTYPRSIAS 325
++ V + ++ ++ L +D E++ + EE R
Sbjct: 1584 DDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQLEE-------MRKREAED 1636
Query: 326 SVRRKDERRKEKREETRERKKREKAKKQEELKQLKNLKRKEILAKLEKLRKVTGNEMLGL 385
R+++ERR+++ E T+ + ++ +++ +L+ +R++ E R++ E GL
Sbjct: 1637 RARQEEERRRQEEERTKRDAEEKRRQEEGYYSRLEAERRRQ---HDEAARRLLEPEAPGL 1693
Query: 386 EEGDLEDDFDP 396
L D++P
Sbjct: 1694 CRPPLPRDYEP 1704
>gi|18375528 UPF3 regulator of nonsense transcripts homolog B
isoform 1 [Homo sapiens]
Length = 483
Score = 55.1 bits (131), Expect = 2e-07
Identities = 79/377 (20%), Positives = 159/377 (42%), Gaps = 64/377 (16%)
Query: 22 FAARYNRYREREELQRLKDRYGDRDSSSDSSSESDSSDERVEFDPQQERDFYKTLSLLKK 81
+A Y ++ +E++ +DR+ D ++ VEF P Q+ KT KK
Sbjct: 94 YARAYINFKNQEDIILFRDRF---DGYVFLDNKGQEYPAIVEFAPFQKAAKKKT----KK 146
Query: 82 KDPRIYQKDATFYNRTASSSDSEEDPEALEKQKKVRPMYLKDYERKVILEKAGKYVDEEN 141
+D ++ D +DPE +K Y D E+ + + + EE
Sbjct: 147 RDTKVGTID--------------DDPE----YRKFLESYATDNEK---MTSTPETLLEEI 185
Query: 142 SDGETSNHRL---QETSSQSYVEEQKQLKESFRAFVEDSEDEDGAGEGGSSLLQKRAKTR 198
E N L + T S+++ +++++E R ++R +
Sbjct: 186 ---EAKNRELIAKKTTPLLSFLKNKQRMREEKRE-------------------ERRRREI 223
Query: 199 QEKAQEEADYIEWLKGQKEIRNP-DSLKELTHLKEYWNDPELDEGERFLRDYIL---NKR 254
+ K Q E + +W + +K R + LK++ + E D DE + + ++L N++
Sbjct: 224 ERKRQREEERRKWKEEEKRKRKDIEKLKKIDRIPE--RDKLKDEPKIKVHRFLLQAVNQK 281
Query: 255 YEEEEEEEEDEEEMEEEEGVHGPPVQLAVDDSSDEGELFLKKQEDFEQKYNFRFEEPDSA 314
++ E+ DE+E+++ E + D+ + L K+ D E K + + + P+
Sbjct: 282 NLLKKPEKGDEKELDKREKAKKLDKENLSDERASGQSCTLPKRSDSELK-DEKPKRPEDE 340
Query: 315 SVKTYPRSIASSVRRKD----ERRKEKREETRERKKREKAKKQEELKQLKNLKRKEILAK 370
S + Y R ++ ER + KR+E R+++E+ +K++ K+ + +KE
Sbjct: 341 SGRDYREREREYERDQERILRERERLKRQEEERRRQKERYEKEKTFKRKEEEMKKEKDTL 400
Query: 371 LEKLRKVTGNEMLGLEE 387
+K +K E +G E
Sbjct: 401 RDKGKKAESTESIGSSE 417
Score = 38.1 bits (87), Expect = 0.028
Identities = 59/244 (24%), Positives = 94/244 (38%), Gaps = 36/244 (14%)
Query: 201 KAQEEADYIEWLKGQKEIRNPDSLKELTHLKEYWNDPELDEGERFLRDYILNKRYEEEEE 260
K QE +E+ QK + ++ T + +DPE +FL Y + E+
Sbjct: 123 KGQEYPAIVEFAPFQKAAKKKTKKRD-TKVGTIDDDPEY---RKFLESYAT----DNEKM 174
Query: 261 EEEDEEEMEEEEGVHGPPVQLAVDDSSDEGELFLKKQEDFEQKYNFRFEEPDSASVKTYP 320
E +EE E + +L ++ KQ E+K R
Sbjct: 175 TSTPETLLEEIEAKNR---ELIAKKTTPLLSFLKNKQRMREEKREERRR----------- 220
Query: 321 RSIASSVRRKDERRKEKREETRERKKREKAKKQEELKQLKNLK-RKEILAKLEKLRKVTG 379
R I +R++ERRK K EE R+RK EK KK + + + LK +I L+ V
Sbjct: 221 REIERKRQREEERRKWKEEEKRKRKDIEKLKKIDRIPERDKLKDEPKIKVHRFLLQAVNQ 280
Query: 380 NEMLGLEEGDLEDDFDPAQHDQLMQK-CFGDEYYGA------------VEEEKPQFEEEE 426
+L E E + D + + + K DE +++EKP+ E+E
Sbjct: 281 KNLLKKPEKGDEKELDKREKAKKLDKENLSDERASGQSCTLPKRSDSELKDEKPKRPEDE 340
Query: 427 GLED 430
D
Sbjct: 341 SGRD 344
>gi|22035604 mitogen-activated protein kinase kinase kinase kinase 4
isoform 2 [Homo sapiens]
Length = 1320
Score = 55.1 bits (131), Expect = 2e-07
Identities = 61/293 (20%), Positives = 129/293 (44%), Gaps = 23/293 (7%)
Query: 221 PDSLKELTHLKEYWNDPELDEGERFLRDYILNKRYEEEEEEEEDEEEMEEEEGVHGPPVQ 280
P+ + LK++ + GE+ +Y + EEEEE E E E V G
Sbjct: 293 PNERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPG---- 348
Query: 281 LAVDDSSDEGELFLKKQEDFEQKYNFR----FEEPDSASVKTYPRSIASSVRRKDERRKE 336
+S+ + +QE+ E+ R +E + Y R + + +++ E++KE
Sbjct: 349 ----ESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKE 404
Query: 337 KRE--ETRERKKREKAKKQEELKQLKNLKRKEILAKLEKLRKVTGNEMLGLEEGDLEDDF 394
+R E ++R++RE ++QE ++ + + K L +LE+ RK E E++
Sbjct: 405 QRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEE------ERRRAEEEK 458
Query: 395 DPAQHDQLMQKCFGDEYYGAVEEEKPQFEEEEGLEDDWNWDTWDGPEQEGDWSQQELHCE 454
+ +Q + +E +E + Q +E+ + + W + ++ + Q++L +
Sbjct: 459 RRVEREQEYIRRQLEEEQRHLEVLQQQLLQEQAMLLECRWREME-EHRQAERLQRQLQ-Q 516
Query: 455 DPNFNMDADYDPSQPRKKKREAPLTGKKKRKSPFAAAVGQEKPVFEPGDKTFE 507
+ + + +D +P + + P +++R P A + K +EP D+ E
Sbjct: 517 EQAYLLSLQHDHRRPHPQHSQQPPPPQQERSKPSFHA-PEPKAHYEPADRARE 568
Score = 33.1 bits (74), Expect = 0.91
Identities = 51/268 (19%), Positives = 100/268 (37%), Gaps = 64/268 (23%)
Query: 88 QKDATFYNRTASSSDSEEDPEALEKQKKVRPMYLKDYERKVILEKAGKYVDEENSDGETS 147
+KD T Y + S + EE PE ++ P + + + L + + +EN + +
Sbjct: 315 EKDETEYEYSGSEEEEEEVPE-----QEGEPSSIVNVPGESTLRRDFLRLQQENKERSEA 369
Query: 148 NHRLQETSSQSYVEEQKQLKESFRAFVEDSEDEDGAGEGGSSLLQKRAKTRQEKAQEEAD 207
R Q+ + + EQ++ K LL +R K +++ ++
Sbjct: 370 LRR-QQLLQEQQLREQEEYKRQ--------------------LLAERQKRIEQQKEQRRR 408
Query: 208 YIEWLKGQKEIRNPDSLKELTHLKEYWNDPELDEGERFLRDYILNKRYEEEEEEEEDEEE 267
E + ++E R ++ +E L+E ER R +EEEE EEE
Sbjct: 409 LEEQQRREREARRQQEREQ--RRREQEEKRRLEELER---------RRKEEEERRRAEEE 457
Query: 268 MEEEEGVHGPPVQLAVDDSSDEGELFLKKQEDFEQKYNFRFEEPDSASVKTYPRSIASSV 327
K++ + EQ+Y R E + ++ + +
Sbjct: 458 ---------------------------KRRVEREQEYIRRQLEEEQRHLEVLQQQLLQEQ 490
Query: 328 RRKDERRKEKREETRERKKREKAKKQEE 355
E R + EE R+ ++ ++ +QE+
Sbjct: 491 AMLLECRWREMEEHRQAERLQRQLQQEQ 518
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 54.7 bits (130), Expect = 3e-07
Identities = 66/337 (19%), Positives = 135/337 (40%), Gaps = 40/337 (11%)
Query: 30 REREELQRLKDRYGDRDSSSDSSSESDSSDERVEFDPQQERDFYKTLSLLKKKDPRIYQK 89
RER+ QR K+R ++ ++ E + +R + D Q+ER+ +++D ++
Sbjct: 111 RERDR-QREKERNRQKERERETEREGERGRDR-QTDGQRERE--------RQRDAEKERE 160
Query: 90 DATFYNRTASSSDSEEDPEALEKQKKVRPMYLKDYERKVILEKAGKYVDEENSDGETSNH 149
T R + + + EK ++ R ER+ EK K D + G
Sbjct: 161 RQTDRERQRQTERNRQKEREREKNRQERR------ERERQREKENKTEDRHSERGR-ERE 213
Query: 150 RLQETSSQSYVEEQKQLKESFRAFVEDSEDEDGAGEGGSSLLQKRAKTRQEKAQEEADYI 209
R +ET +++ + Q + + E ++ E S +R K R+ + + D
Sbjct: 214 RERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRD 273
Query: 210 EWLKGQKEIRNPDSLKELTHLKEYWNDPELDEGERFLRDYILNKRYEEEEEEEEDEEEME 269
K ++ R D ++ ++ + + + R+ N++ E E E E + E
Sbjct: 274 RRQKERE--RQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQR 331
Query: 270 EEEGVHGPPVQLAVDDSSDEGELFLKKQEDFEQKYNFRFEEPDSASVKTYPRSIASSVRR 329
E E D E E K+Q + +++ N + T + R
Sbjct: 332 ETER-----------DREKERERKRKRQTEMDRERNRQ----------TGREGRRQAERE 370
Query: 330 KDERRKEKREETRERKKREKAKKQEELKQLKNLKRKE 366
++ R+ R+ RER++RE+ + ++ K+ + K+
Sbjct: 371 RERERERDRQSAREREERERDRDRDRQKERERQTEKD 407
Score = 53.1 bits (126), Expect = 9e-07
Identities = 65/337 (19%), Positives = 135/337 (40%), Gaps = 27/337 (8%)
Query: 30 REREELQRLKDRYGD-RDSSSDSSSESDSSDERVEFDPQQERDFYKTLSLLKKKDPRIYQ 88
R R Q KD GD R+ + E + E + ++R+ + +K+D R +
Sbjct: 38 RRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRD-RHRE 96
Query: 89 KDATFYNRTASSSDSEEDPEALEKQKKVRPMYLKDYERKVILEKAGKYVDEENSDGETSN 148
+ +D E D + EK++ + ER+ E+ G E D +T
Sbjct: 97 RQRDREKERERQTDRERDRQR-EKERN------RQKERERETEREG----ERGRDRQTDG 145
Query: 149 HRLQETSSQSYVEEQKQLKESFRAFVEDSEDEDGAGEGGSSLLQKRAKTRQEKAQEEADY 208
R +E + E ++Q + E + ++ ++R K RQE+ + E
Sbjct: 146 QRERERQRDAEKERERQTDRERQRQTERNRQKE----------REREKNRQERRERERQR 195
Query: 209 IEWLKGQKEIRNPDSLKELTHLKEYWNDPELDEGERFLRDYILNKRYEEEEEEEEDEEEM 268
+ + + E R+ + +E +E + E + + R+ ++ E E E++ + E
Sbjct: 196 EK--ENKTEDRHSERGRERERERE--TETETERKRQTDRERDRQRKTEREREKQAERERA 251
Query: 269 EEEEGVHGPPVQLAVDDSSDEGELFLKKQEDFEQKYNFRFEEPDSASVKTYPRSIASSVR 328
E E + D D +++ ++K R E K + R
Sbjct: 252 SERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERER 311
Query: 329 RKDERRKEKREETRERKKREKAKKQEELKQLKNLKRK 365
++ +R+ +RE RER+++ + ++ E ++ + KR+
Sbjct: 312 ERNRKRERERERERERERQRETERDREKERERKRKRQ 348
Score = 47.0 bits (110), Expect = 6e-05
Identities = 75/367 (20%), Positives = 145/367 (39%), Gaps = 50/367 (13%)
Query: 27 NRYRERE-----ELQRLKDRYGD--------RDSSSDSSSESDSSDER-VEFDPQQERDF 72
NR +ERE E +R +DR D RD+ + ++D +R E + Q+ER+
Sbjct: 122 NRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKERER 181
Query: 73 YKTLSLLKKKDPRIYQKDATFYNRTASSSDSEEDPEA-LEKQKKVRPMYLKDYERKVILE 131
K ++++ + +++ T + + E + E E ++K + +D +RK E
Sbjct: 182 EKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTERE 241
Query: 132 KAGKYVDEENSDGETSNHRLQETSSQSYVEEQKQLKESFRAFVEDSEDEDGAGEGGSSLL 191
+ + E S+ ET + +E + ++ KE R + E
Sbjct: 242 REKQAERERASERETERDKERERERDRDRDRDRRQKERER---QTDRKRQRRTERDRETE 298
Query: 192 QKRAKTRQEKAQEEADYIEWLKGQKEIRNPDSLKELTHLKEYWNDPELDEGERFLRDYIL 251
+KR + R+ + + E + +K R + +E +E D E + + R +
Sbjct: 299 RKRERQRERERERE-------RNRKRERERERERERERQRETERDREKERERKRKRQTEM 351
Query: 252 NK-------RYEEEEEEEEDEEEMEEEEGVHGPPVQLAVDDSSDEGELFLKKQEDFEQKY 304
++ R + E E E E E + S+ E E + ++ QK
Sbjct: 352 DRERNRQTGREGRRQAERERERERERDR------------QSAREREERERDRDRDRQKE 399
Query: 305 NFRFEEPDSASVKTYPRSIASSVRRKDERRKEKREETRERKK---REKAKKQEELKQLKN 361
R E D + + R KD + RE RER+K RE+ ++++ +Q
Sbjct: 400 RERQTEKDRDGQRETEKQ---REREKDRESERGRERGREREKQKGRERDRERQTDRQAGR 456
Query: 362 LKRKEIL 368
+++ L
Sbjct: 457 QRKRSTL 463
Score = 42.4 bits (98), Expect = 0.002
Identities = 72/333 (21%), Positives = 130/333 (39%), Gaps = 46/333 (13%)
Query: 180 EDGAGEGGSSLLQKRAKTRQEKAQEEADYIEWLKGQKEIRNPDSLKELTHLKEYWNDPEL 239
+D G+ QK + R+EK Q E E + ++ R D ++ +E D E
Sbjct: 47 KDADGDDRERNRQKERERRREKRQTER---ETDRKRERRREKDRHRKRDRHRERQRDREK 103
Query: 240 DEGERFLRDYILNKRYEEEEEEEEDEEEMEEEEGVHGPPVQLAVDDSSDEGELFLKKQED 299
+ + R+ +++ E+E +++ E E EG G D +G+ ++Q D
Sbjct: 104 ERERQTDRER--DRQREKERNRQKERERETEREGERGR-------DRQTDGQRERERQRD 154
Query: 300 FE-----QKYNFRFEEPDSASVKTYPRSIASSVRRKDERRKEK--------------REE 340
E Q R + + K R RR+ ER++EK RE
Sbjct: 155 AEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERER 214
Query: 341 TRERKKREKAKKQ---EELKQLKNLKRKEILAKLEKL-RKVTGNEMLGLEEGDLEDDFDP 396
RE + + K+Q E +Q K + +E A+ E+ + T + E D + D D
Sbjct: 215 ERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDR 274
Query: 397 AQHD---QLMQKCFGDEYYGAVEEEKPQFEEEEGLEDDWNWDTWDGPEQEGDWSQQELHC 453
Q + Q +K E K + + E E + N E+E + +Q
Sbjct: 275 RQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQR--- 331
Query: 454 EDPNFNMDADYDPSQPRKKKREAPLTGKKKRKS 486
+ D + + RK+KR+ + ++ R++
Sbjct: 332 -----ETERDREKERERKRKRQTEMDRERNRQT 359
>gi|148806928 hypothetical protein LOC57482 [Homo sapiens]
Length = 1233
Score = 54.7 bits (130), Expect = 3e-07
Identities = 91/382 (23%), Positives = 156/382 (40%), Gaps = 72/382 (18%)
Query: 143 DGETSNHRLQETSSQSYVEEQKQ-LKESFRAFVEDSEDEDGAGEGGSSLLQKRAKTRQEK 201
D + H+L V+ +KQ + + R +D + E G E L +
Sbjct: 153 DNSAAKHKLA-------VKPKKQRVSKKHRRLAQDPQHEQGGLESRPCL--------DQN 197
Query: 202 AQEEADYIEWLKGQKEIRNP-DSLKELTHLKEYWNDPELDEGERFLRDYILNKRYEEEEE 260
D W +E NP DS +E ++YW + E + +R + +R EE+
Sbjct: 198 GHPGEDKPTW---HEEEPNPLDSEEERRRQEDYWRELEA-KCKRQKAEAAEKRRLEEQRL 253
Query: 261 --------EEEDEEEMEEEEGVHGPPVQLAVDDSSDEGELFLKKQ--EDFEQKYNFRFEE 310
EE +E+ EEEG P A +E + L+ ED E++ E
Sbjct: 254 QALERRLWEENRRQELLEEEGEGQEPPLEAERAPREEQQRSLEAPGWEDAERREREERER 313
Query: 311 PDSASVKTYPRSIASSVRRK--------DERRKEKREETR-----ERKKREKAKKQEELK 357
++ + ++ A + R+ +ERR+++ EE R +R++ E+A+ EEL+
Sbjct: 314 LEAEEERRRLQAQAQAEERRRLEEDARLEERRRQEEEEGRCAEELKRQEEEEAEGWEELE 373
Query: 358 QLKNLKR--KEILAKLEKLRKVTGNEMLGLEEGD----LED----------DFDPAQHDQ 401
Q + + E L + + R+ E LG EE + LED DF+ DQ
Sbjct: 374 QQEAEVQGPPEALEETGEGRRGAEEEDLGEEEEEGQAHLEDWRGQLSELLNDFEERLEDQ 433
Query: 402 LMQKCFGDEYY----GAVEEEKPQFE---EEEGLEDDWNWDTWDGPEQEGDWSQQELHCE 454
K G + G EE+ P+ E E++G D+ GPE++ + E
Sbjct: 434 ERLKPEGQREHSEEPGICEEQNPEAERRREQQGRSGDFQGADRPGPEEKREEGDTE---- 489
Query: 455 DPNFNMDADYDPSQPRKKKREA 476
P + + +QP +++EA
Sbjct: 490 -PLLKQEGPVEAAQPPVERKEA 510
Score = 43.1 bits (100), Expect = 9e-04
Identities = 67/317 (21%), Positives = 126/317 (39%), Gaps = 35/317 (11%)
Query: 104 EEDPEALEKQKKVRPM--YLKDYERKVILEKAGKYVDEENSDGETSNHRLQETSSQSYVE 161
EE+P L+ +++ R Y ++ E K +KA E RLQ + + E
Sbjct: 209 EEEPNPLDSEEERRRQEDYWRELEAKCKRQKA-----EAAEKRRLEEQRLQALERRLWEE 263
Query: 162 EQKQLKESFRAFVEDSEDEDGAGEGGSSLLQKRAKTRQEKAQE----------EADYIEW 211
++Q + +E+G G+ ++ + Q+++ E E + E
Sbjct: 264 NRRQ----------ELLEEEGEGQEPPLEAERAPREEQQRSLEAPGWEDAERREREERER 313
Query: 212 LKGQKEIRNPDSLKELTHLKEYWNDPELDEGERFLRDY---ILNKRYEEEEEEEEDEEEM 268
L+ ++E R + + + D L+E R + + +EEEE E EE
Sbjct: 314 LEAEEERRRLQAQAQAEERRRLEEDARLEERRRQEEEEGRCAEELKRQEEEEAEGWEELE 373
Query: 269 EEEEGVHGPPVQLAVDDSSDEG--ELFLKKQEDFEQKYNFRFEEPDSASVKTYPRSIASS 326
++E V GPP L G E L ++E+ Q + + S + + +
Sbjct: 374 QQEAEVQGPPEALEETGEGRRGAEEEDLGEEEEEGQAHLEDWRGQLSELLNDFEERLEDQ 433
Query: 327 VRRKDERRKEKREETR--ERKKREKAKKQEELKQLKNLKRKEILAKLEKLRKVTGNEMLG 384
R K E ++E EE E + E +++E+ + + + + EK R+ E L
Sbjct: 434 ERLKPEGQREHSEEPGICEEQNPEAERRREQQGRSGDFQGADRPGPEEK-REEGDTEPLL 492
Query: 385 LEEGDLEDDFDPAQHDQ 401
+EG +E P + +
Sbjct: 493 KQEGPVEAAQPPVERKE 509
Score = 30.4 bits (67), Expect = 5.9
Identities = 23/104 (22%), Positives = 46/104 (44%), Gaps = 6/104 (5%)
Query: 256 EEEEEEEEDEEEMEEEEGVHGPPVQLAVDDS-SDEGELFLKKQEDFEQKYNFRFEEPDSA 314
EE + ++ DEEE E PP+ + S E K++ + +++ +
Sbjct: 1022 EERKGQKRDEEEEATERKPASPPLPATQQEKPSQTPEAGRKEKPMLQSRHSLDGSKLTEK 1081
Query: 315 SVKTYPRSIASSVR-----RKDERRKEKREETRERKKREKAKKQ 353
P I +++ R+ + +E+R++ RE K+ EK K+
Sbjct: 1082 VETAQPLWITLALQKQKGFREQQATREERKQAREAKQAEKLSKE 1125
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 54.7 bits (130), Expect = 3e-07
Identities = 68/292 (23%), Positives = 117/292 (40%), Gaps = 54/292 (18%)
Query: 84 PRIYQKDATFYNRTASSSDSEEDPEALEKQKKVRPMYLKDYERKVILEKAGKYVDEENSD 143
PR K N E++ + LE + R + R+ + E + ++E
Sbjct: 512 PRSVMKSFIKRNTPLRMDPKEKERQRLENLR--RKEEAEQLRRQKVEEDKRRRLEEVKLK 569
Query: 144 GETSNHRL---QETSSQSYVEEQKQLKESFRAFVEDSEDEDGAGEGGSSLLQKRAKTRQE 200
E ++ +E Q E++KQ+++ F E +E +K A + E
Sbjct: 570 REERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKME 629
Query: 201 ------KAQEEADYIEWLKGQKEIRNPDSLKELTHLKEYWNDPELDEGERFLRDYILNKR 254
K +EEA + WL+ ++E R L L KE +E ER LR KR
Sbjct: 630 EVEARRKQEEEARRLRWLQQEEEERRHQEL--LQKKKE-------EEQER-LRKAAEAKR 679
Query: 255 YEEEEEEEEDEEEMEEEEGVHGPPVQLAVDDSSDEGELFLKKQEDFEQKYNFRFEEPDSA 314
E+ E+E E+E E+E E ++QE EQ+
Sbjct: 680 LAEQREQERREQERREQE----------------RREQERREQERREQE----------- 712
Query: 315 SVKTYPRSIASSVRRKDERRKEKREETRERKKREKAKKQEELKQLKNLKRKE 366
R +A RR+++ R + E +ER+K + +K++ ++L+ K+KE
Sbjct: 713 ------RQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKE 758
Score = 45.4 bits (106), Expect = 2e-04
Identities = 44/191 (23%), Positives = 84/191 (43%), Gaps = 26/191 (13%)
Query: 194 RAKTRQEKAQEEADYIEWLKGQKEIRNPDSLKELTHLKEYWNDPELDEGERFLRDYILNK 253
+ + R K + + +E +K +K+ + ++ E + L E E+ + K
Sbjct: 569 KREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAE-EKAKKKAAAKK 627
Query: 254 RYEEEEEEEEDEE-------EMEEEEGVHGPPVQLAVDDSSDEGELFLKKQEDFEQKYNF 306
E E +++EE + EEEE H EL KK+E+ +++
Sbjct: 628 MEEVEARRKQEEEARRLRWLQQEEEERRHQ--------------ELLQKKKEEEQERLRK 673
Query: 307 RFEEPDSASVKTYPR---SIASSVRRKDERRK-EKREETRERKKREKAKKQEELKQLKNL 362
E A + R RR+ ERR+ E+RE+ R+ ++E+ ++QE L+ + L
Sbjct: 674 AAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAEREL 733
Query: 363 KRKEILAKLEK 373
+ +E +L+K
Sbjct: 734 QEREKALRLQK 744
Score = 31.2 bits (69), Expect = 3.5
Identities = 22/76 (28%), Positives = 38/76 (50%), Gaps = 14/76 (18%)
Query: 317 KTYPRSIASSVRRKDE----RRKEKREETRERKKREKAKKQEELK----------QLKNL 362
K R ++RRK+E RR++ E+ R R + K K++E L+ Q+K
Sbjct: 531 KEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEE 590
Query: 363 KRKEILAKLEKLRKVT 378
K+K+I K ++ + T
Sbjct: 591 KKKQIEQKFAQIDEKT 606
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.129 0.368
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,688,596
Number of Sequences: 37866
Number of extensions: 1806494
Number of successful extensions: 33382
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 462
Number of HSP's successfully gapped in prelim test: 946
Number of HSP's that attempted gapping in prelim test: 14386
Number of HSP's gapped (non-prelim): 8697
length of query: 709
length of database: 18,247,518
effective HSP length: 109
effective length of query: 600
effective length of database: 14,120,124
effective search space: 8472074400
effective search space used: 8472074400
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.