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Search of human proteins with 145580610
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|145580610 WD repeat domain 62 isoform 2 [Homo sapiens]
(1518 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|145580610 WD repeat domain 62 isoform 2 [Homo sapiens] 3091 0.0
gi|145580608 WD repeat domain 62 isoform 1 [Homo sapiens] 3085 0.0
gi|190684671 mitogen-activated protein kinase binding protein 1 ... 1033 0.0
gi|190684677 mitogen-activated protein kinase binding protein 1 ... 1027 0.0
gi|124028512 WD40-repeat protein upregulated in HCC isoform b [H... 82 5e-15
gi|32189425 WD repeat domain 69 [Homo sapiens] 81 7e-15
gi|34485720 echinoderm microtubule associated protein like 5 [Ho... 75 6e-13
gi|223005862 echinoderm microtubule associated protein like 6 [H... 72 4e-12
gi|56790932 echinoderm microtubule associated protein like 1 iso... 70 1e-11
gi|56790930 echinoderm microtubule associated protein like 1 iso... 70 1e-11
gi|48928050 F-box and WD repeat domain containing 11 isoform C [... 66 2e-10
gi|48928048 F-box and WD repeat domain containing 11 isoform A [... 66 2e-10
gi|48928046 F-box and WD repeat domain containing 11 isoform B [... 66 2e-10
gi|26665869 WD repeat domain 51B [Homo sapiens] 66 2e-10
gi|4502477 beta-transducin repeat containing protein isoform 2 [... 65 4e-10
gi|16117783 beta-transducin repeat containing protein isoform 1 ... 65 4e-10
gi|6912356 echinoderm microtubule associated protein like 2 [Hom... 65 5e-10
gi|16554629 WD repeat domain 5 [Homo sapiens] 64 1e-09
gi|16554627 WD repeat domain 5 [Homo sapiens] 64 1e-09
gi|223029510 echinoderm microtubule associated protein like 4 is... 61 9e-09
gi|19923497 echinoderm microtubule associated protein like 4 iso... 61 9e-09
gi|94400919 WD repeat domain 90 [Homo sapiens] 60 1e-08
gi|21071067 TBP-associated factor 5 [Homo sapiens] 59 3e-08
gi|216548382 WD repeat domain 47 isoform 3 [Homo sapiens] 58 8e-08
gi|216548378 WD repeat domain 47 isoform 1 [Homo sapiens] 58 8e-08
gi|216548347 WD repeat domain 47 isoform 2 [Homo sapiens] 58 8e-08
gi|110227615 echinoderm microtubule associated protein like 3 [H... 58 8e-08
gi|31377846 WD repeat domain 52 [Homo sapiens] 57 1e-07
gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens] 56 2e-07
gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens] 56 2e-07
>gi|145580610 WD repeat domain 62 isoform 2 [Homo sapiens]
Length = 1518
Score = 3091 bits (8015), Expect = 0.0
Identities = 1518/1518 (100%), Positives = 1518/1518 (100%)
Query: 1 MAAVGSGGYARNDAGEKLPSVMAGVPARRGQSSPPPAPPICLRRRTRLSTASEETVQNRV 60
MAAVGSGGYARNDAGEKLPSVMAGVPARRGQSSPPPAPPICLRRRTRLSTASEETVQNRV
Sbjct: 1 MAAVGSGGYARNDAGEKLPSVMAGVPARRGQSSPPPAPPICLRRRTRLSTASEETVQNRV 60
Query: 61 SLEKVLGITAQNSSGLTCDPGTGHVAYLAGCVVVILDPKENKQQHIFNTARKSLSALAFS 120
SLEKVLGITAQNSSGLTCDPGTGHVAYLAGCVVVILDPKENKQQHIFNTARKSLSALAFS
Sbjct: 61 SLEKVLGITAQNSSGLTCDPGTGHVAYLAGCVVVILDPKENKQQHIFNTARKSLSALAFS 120
Query: 121 PDGKYIVTGENGHRPAVRIWDVEEKNQVAEMLGHKYGVACVAFSPNMKHIVSMGYQHDMV 180
PDGKYIVTGENGHRPAVRIWDVEEKNQVAEMLGHKYGVACVAFSPNMKHIVSMGYQHDMV
Sbjct: 121 PDGKYIVTGENGHRPAVRIWDVEEKNQVAEMLGHKYGVACVAFSPNMKHIVSMGYQHDMV 180
Query: 181 LNVWDWKKDIVVASNKVSCRVIALSFSEDSSYFVTVGNRHVRFWFLEVSTETKVTSTVPL 240
LNVWDWKKDIVVASNKVSCRVIALSFSEDSSYFVTVGNRHVRFWFLEVSTETKVTSTVPL
Sbjct: 181 LNVWDWKKDIVVASNKVSCRVIALSFSEDSSYFVTVGNRHVRFWFLEVSTETKVTSTVPL 240
Query: 241 VGRSGILGELHNNIFCGVACGRGRMAGSTFCVSYSGLLCQFNEKRVLEKWINLKVSLSSC 300
VGRSGILGELHNNIFCGVACGRGRMAGSTFCVSYSGLLCQFNEKRVLEKWINLKVSLSSC
Sbjct: 241 VGRSGILGELHNNIFCGVACGRGRMAGSTFCVSYSGLLCQFNEKRVLEKWINLKVSLSSC 300
Query: 301 LCVSQELIFCGCTDGIVRIFQAHSLHYLANLPKPHYLGVDVAQGLEPSFLFHRKAEAVYP 360
LCVSQELIFCGCTDGIVRIFQAHSLHYLANLPKPHYLGVDVAQGLEPSFLFHRKAEAVYP
Sbjct: 301 LCVSQELIFCGCTDGIVRIFQAHSLHYLANLPKPHYLGVDVAQGLEPSFLFHRKAEAVYP 360
Query: 361 DTVALTFDPIHQWLSCVYKDHSIYIWDVKDINRVGKVWSELFHSSYVWNVEVYPEFEDQR 420
DTVALTFDPIHQWLSCVYKDHSIYIWDVKDINRVGKVWSELFHSSYVWNVEVYPEFEDQR
Sbjct: 361 DTVALTFDPIHQWLSCVYKDHSIYIWDVKDINRVGKVWSELFHSSYVWNVEVYPEFEDQR 420
Query: 421 ACLPSGSFLTCSSDNTIRFWNLDSSPDSHWQKNIFSNTLLKVVYVENDIQHLQDMSHFPD 480
ACLPSGSFLTCSSDNTIRFWNLDSSPDSHWQKNIFSNTLLKVVYVENDIQHLQDMSHFPD
Sbjct: 421 ACLPSGSFLTCSSDNTIRFWNLDSSPDSHWQKNIFSNTLLKVVYVENDIQHLQDMSHFPD 480
Query: 481 RGSENGTPMDVKAGVRVMQVSPDGQHLASGDRSGNLRIHELHFMDELVKVEAHDAEVLCL 540
RGSENGTPMDVKAGVRVMQVSPDGQHLASGDRSGNLRIHELHFMDELVKVEAHDAEVLCL
Sbjct: 481 RGSENGTPMDVKAGVRVMQVSPDGQHLASGDRSGNLRIHELHFMDELVKVEAHDAEVLCL 540
Query: 541 EYSKPETGLTLLASASRDRLIHVLNVEKNYNLEQTLDDHSSSITAIKFAGNRDIQMISCG 600
EYSKPETGLTLLASASRDRLIHVLNVEKNYNLEQTLDDHSSSITAIKFAGNRDIQMISCG
Sbjct: 541 EYSKPETGLTLLASASRDRLIHVLNVEKNYNLEQTLDDHSSSITAIKFAGNRDIQMISCG 600
Query: 601 ADKSIYFRSAQQGSDGLHFVRTHHVAEKTTLYDMDIDITQKYVAVACQDRNVRVYNTVNG 660
ADKSIYFRSAQQGSDGLHFVRTHHVAEKTTLYDMDIDITQKYVAVACQDRNVRVYNTVNG
Sbjct: 601 ADKSIYFRSAQQGSDGLHFVRTHHVAEKTTLYDMDIDITQKYVAVACQDRNVRVYNTVNG 660
Query: 661 KQKKCYKGSQGDEGSLLKVHVDPSGTFLATSCSDKSISVIDFYSGECIAKMFGHSEIITS 720
KQKKCYKGSQGDEGSLLKVHVDPSGTFLATSCSDKSISVIDFYSGECIAKMFGHSEIITS
Sbjct: 661 KQKKCYKGSQGDEGSLLKVHVDPSGTFLATSCSDKSISVIDFYSGECIAKMFGHSEIITS 720
Query: 721 MKFTYDCHHLITVSGDSCVFIWHLGPEITNCMKQHLLEIDHRQQQQHTNDKKRSGHPRQD 780
MKFTYDCHHLITVSGDSCVFIWHLGPEITNCMKQHLLEIDHRQQQQHTNDKKRSGHPRQD
Sbjct: 721 MKFTYDCHHLITVSGDSCVFIWHLGPEITNCMKQHLLEIDHRQQQQHTNDKKRSGHPRQD 780
Query: 781 TYVSTPSEIHSLSPGEQTEDDLEEECEPEEMLKTPSKDSLDPDPRCLLTNGKLPLWAKRL 840
TYVSTPSEIHSLSPGEQTEDDLEEECEPEEMLKTPSKDSLDPDPRCLLTNGKLPLWAKRL
Sbjct: 781 TYVSTPSEIHSLSPGEQTEDDLEEECEPEEMLKTPSKDSLDPDPRCLLTNGKLPLWAKRL 840
Query: 841 LGDDDVADGLAFHAKRSYQPHGRWAERAGQEPLKTILDAQDLDCYFTPMKPESLENSILD 900
LGDDDVADGLAFHAKRSYQPHGRWAERAGQEPLKTILDAQDLDCYFTPMKPESLENSILD
Sbjct: 841 LGDDDVADGLAFHAKRSYQPHGRWAERAGQEPLKTILDAQDLDCYFTPMKPESLENSILD 900
Query: 901 SLEPQSLASLLSESESPQEAGRGHPSFLPQQKESSEASELILYSLEAEVTVTGTDSQYCR 960
SLEPQSLASLLSESESPQEAGRGHPSFLPQQKESSEASELILYSLEAEVTVTGTDSQYCR
Sbjct: 901 SLEPQSLASLLSESESPQEAGRGHPSFLPQQKESSEASELILYSLEAEVTVTGTDSQYCR 960
Query: 961 KEVEAGPGDQQGDSYLRVSSDSPKDQSPPEDSGESEADLECSFAAIHSPAPPPDPAPRFA 1020
KEVEAGPGDQQGDSYLRVSSDSPKDQSPPEDSGESEADLECSFAAIHSPAPPPDPAPRFA
Sbjct: 961 KEVEAGPGDQQGDSYLRVSSDSPKDQSPPEDSGESEADLECSFAAIHSPAPPPDPAPRFA 1020
Query: 1021 TSLPHFPGCAGPTEDELSLPEGPSVPSSSLPQTPEQEKFLRHHFETLTESPCRALGDVEA 1080
TSLPHFPGCAGPTEDELSLPEGPSVPSSSLPQTPEQEKFLRHHFETLTESPCRALGDVEA
Sbjct: 1021 TSLPHFPGCAGPTEDELSLPEGPSVPSSSLPQTPEQEKFLRHHFETLTESPCRALGDVEA 1080
Query: 1081 SEAEDHFFNPRLSISTQFLSSLQKASRFTHTFPPRATQCLVKSPEVKLMDRGGSQPRAGT 1140
SEAEDHFFNPRLSISTQFLSSLQKASRFTHTFPPRATQCLVKSPEVKLMDRGGSQPRAGT
Sbjct: 1081 SEAEDHFFNPRLSISTQFLSSLQKASRFTHTFPPRATQCLVKSPEVKLMDRGGSQPRAGT 1140
Query: 1141 GYASPDRTHVLAAGKAEETLEAWRPPPPCLTSLASCVPASSVLPTDRNLPTPTSAPTPGL 1200
GYASPDRTHVLAAGKAEETLEAWRPPPPCLTSLASCVPASSVLPTDRNLPTPTSAPTPGL
Sbjct: 1141 GYASPDRTHVLAAGKAEETLEAWRPPPPCLTSLASCVPASSVLPTDRNLPTPTSAPTPGL 1200
Query: 1201 AQGVHAPSTCSYMEATASSRARISRSISLGDSEGPIVATLAQPLRRPSSVGELASLGQEL 1260
AQGVHAPSTCSYMEATASSRARISRSISLGDSEGPIVATLAQPLRRPSSVGELASLGQEL
Sbjct: 1201 AQGVHAPSTCSYMEATASSRARISRSISLGDSEGPIVATLAQPLRRPSSVGELASLGQEL 1260
Query: 1261 QAITTATTPSLDSEGQEPALRSWGNHEARANLRLTLSSACDGLLQPPVDTQPGVTVPAVS 1320
QAITTATTPSLDSEGQEPALRSWGNHEARANLRLTLSSACDGLLQPPVDTQPGVTVPAVS
Sbjct: 1261 QAITTATTPSLDSEGQEPALRSWGNHEARANLRLTLSSACDGLLQPPVDTQPGVTVPAVS 1320
Query: 1321 FPAPSPVEESALRLHGSAFRPSLPAPESPGLPAHPSNPQLPEARPGIPGGTASLLEPTSG 1380
FPAPSPVEESALRLHGSAFRPSLPAPESPGLPAHPSNPQLPEARPGIPGGTASLLEPTSG
Sbjct: 1321 FPAPSPVEESALRLHGSAFRPSLPAPESPGLPAHPSNPQLPEARPGIPGGTASLLEPTSG 1380
Query: 1381 ALGLLQGSPARWSEPWVPVEALPPSPLELSRVGNILHRLQTTFQEALDLYRVLVSSGQVD 1440
ALGLLQGSPARWSEPWVPVEALPPSPLELSRVGNILHRLQTTFQEALDLYRVLVSSGQVD
Sbjct: 1381 ALGLLQGSPARWSEPWVPVEALPPSPLELSRVGNILHRLQTTFQEALDLYRVLVSSGQVD 1440
Query: 1441 TGQQQARTELVSTFLWIHSQLEAECLVGTSVAPAQALPSPGPPSPPTLYPLASPDLQALL 1500
TGQQQARTELVSTFLWIHSQLEAECLVGTSVAPAQALPSPGPPSPPTLYPLASPDLQALL
Sbjct: 1441 TGQQQARTELVSTFLWIHSQLEAECLVGTSVAPAQALPSPGPPSPPTLYPLASPDLQALL 1500
Query: 1501 EHYSELLVQAVRRKARGH 1518
EHYSELLVQAVRRKARGH
Sbjct: 1501 EHYSELLVQAVRRKARGH 1518
>gi|145580608 WD repeat domain 62 isoform 1 [Homo sapiens]
Length = 1523
Score = 3085 bits (7999), Expect = 0.0
Identities = 1518/1523 (99%), Positives = 1518/1523 (99%), Gaps = 5/1523 (0%)
Query: 1 MAAVGSGGYARNDAGEKLPSVMAGVPARRGQSSPPPAPPICLRRRTRLSTASEETVQNRV 60
MAAVGSGGYARNDAGEKLPSVMAGVPARRGQSSPPPAPPICLRRRTRLSTASEETVQNRV
Sbjct: 1 MAAVGSGGYARNDAGEKLPSVMAGVPARRGQSSPPPAPPICLRRRTRLSTASEETVQNRV 60
Query: 61 SLEKVLGITAQNSSGLTCDPGTGHVAYLAGCVVVILDPKENKQQHIFNTARKSLSALAFS 120
SLEKVLGITAQNSSGLTCDPGTGHVAYLAGCVVVILDPKENKQQHIFNTARKSLSALAFS
Sbjct: 61 SLEKVLGITAQNSSGLTCDPGTGHVAYLAGCVVVILDPKENKQQHIFNTARKSLSALAFS 120
Query: 121 PDGKYIVTGENGHRPAVRIWDVEEKNQVAEMLGHKYGVACVAFSPNMKHIVSMGYQHDMV 180
PDGKYIVTGENGHRPAVRIWDVEEKNQVAEMLGHKYGVACVAFSPNMKHIVSMGYQHDMV
Sbjct: 121 PDGKYIVTGENGHRPAVRIWDVEEKNQVAEMLGHKYGVACVAFSPNMKHIVSMGYQHDMV 180
Query: 181 LNVWDWKKDIVVASNKVSCRVIALSFSEDSSYFVTVGNRHVRFWFLEVSTETKVTSTVPL 240
LNVWDWKKDIVVASNKVSCRVIALSFSEDSSYFVTVGNRHVRFWFLEVSTETKVTSTVPL
Sbjct: 181 LNVWDWKKDIVVASNKVSCRVIALSFSEDSSYFVTVGNRHVRFWFLEVSTETKVTSTVPL 240
Query: 241 VGRSGILGELHNNIFCGVACGRGRMAGSTFCVSYSGLLCQFNEKRVLEKWINLKVSLSSC 300
VGRSGILGELHNNIFCGVACGRGRMAGSTFCVSYSGLLCQFNEKRVLEKWINLKVSLSSC
Sbjct: 241 VGRSGILGELHNNIFCGVACGRGRMAGSTFCVSYSGLLCQFNEKRVLEKWINLKVSLSSC 300
Query: 301 LCVSQELIFCGCTDGIVRIFQAHSLHYLANLPKPHYLGVDVAQGLEPSFLFHRKAEAVYP 360
LCVSQELIFCGCTDGIVRIFQAHSLHYLANLPKPHYLGVDVAQGLEPSFLFHRKAEAVYP
Sbjct: 301 LCVSQELIFCGCTDGIVRIFQAHSLHYLANLPKPHYLGVDVAQGLEPSFLFHRKAEAVYP 360
Query: 361 DTVALTFDPIHQWLSCVYKDHSIYIWDVKDINRVGKVWSELFHSSYVWNVEVYPEFEDQR 420
DTVALTFDPIHQWLSCVYKDHSIYIWDVKDINRVGKVWSELFHSSYVWNVEVYPEFEDQR
Sbjct: 361 DTVALTFDPIHQWLSCVYKDHSIYIWDVKDINRVGKVWSELFHSSYVWNVEVYPEFEDQR 420
Query: 421 ACLPSGSFLTCSSDNTIRFWNLDSSPDSHWQKNIFSNTLLKVVYVENDIQHLQDMSHFPD 480
ACLPSGSFLTCSSDNTIRFWNLDSSPDSHWQKNIFSNTLLKVVYVENDIQHLQDMSHFPD
Sbjct: 421 ACLPSGSFLTCSSDNTIRFWNLDSSPDSHWQKNIFSNTLLKVVYVENDIQHLQDMSHFPD 480
Query: 481 RGSENGTPMDVKAGVRVMQVSPDGQHLASGDRSGNLRIHELHFMDELVKVEAHDAEVLCL 540
RGSENGTPMDVKAGVRVMQVSPDGQHLASGDRSGNLRIHELHFMDELVKVEAHDAEVLCL
Sbjct: 481 RGSENGTPMDVKAGVRVMQVSPDGQHLASGDRSGNLRIHELHFMDELVKVEAHDAEVLCL 540
Query: 541 EYSKPETGLTLLASASRDRLIHVLNVEKNYNLEQTLDDHSSSITAIKFAGNRDIQMISCG 600
EYSKPETGLTLLASASRDRLIHVLNVEKNYNLEQTLDDHSSSITAIKFAGNRDIQMISCG
Sbjct: 541 EYSKPETGLTLLASASRDRLIHVLNVEKNYNLEQTLDDHSSSITAIKFAGNRDIQMISCG 600
Query: 601 ADKSIYFRSAQQGSDGLHFVRTHHVAEKTTLYDMDIDITQKYVAVACQDRNVRVYNTVNG 660
ADKSIYFRSAQQGSDGLHFVRTHHVAEKTTLYDMDIDITQKYVAVACQDRNVRVYNTVNG
Sbjct: 601 ADKSIYFRSAQQGSDGLHFVRTHHVAEKTTLYDMDIDITQKYVAVACQDRNVRVYNTVNG 660
Query: 661 KQKKCYKGSQGDEGSLLKVHVDPSGTFLATSCSDKSISVIDFYSGECIAKMFGHSEIITS 720
KQKKCYKGSQGDEGSLLKVHVDPSGTFLATSCSDKSISVIDFYSGECIAKMFGHSEIITS
Sbjct: 661 KQKKCYKGSQGDEGSLLKVHVDPSGTFLATSCSDKSISVIDFYSGECIAKMFGHSEIITS 720
Query: 721 MKFTYDCHHLITVSGDSCVFIWHLGPEITNCMKQHLLEIDHRQQQQHTNDKKRSGHPRQD 780
MKFTYDCHHLITVSGDSCVFIWHLGPEITNCMKQHLLEIDHRQQQQHTNDKKRSGHPRQD
Sbjct: 721 MKFTYDCHHLITVSGDSCVFIWHLGPEITNCMKQHLLEIDHRQQQQHTNDKKRSGHPRQD 780
Query: 781 TYVSTPSEIHSLSPGEQTEDDLEEECEPEEMLKTPSKDSLDPDPRCLLTNGKLPLWAKRL 840
TYVSTPSEIHSLSPGEQTEDDLEEECEPEEMLKTPSKDSLDPDPRCLLTNGKLPLWAKRL
Sbjct: 781 TYVSTPSEIHSLSPGEQTEDDLEEECEPEEMLKTPSKDSLDPDPRCLLTNGKLPLWAKRL 840
Query: 841 LGDDDVADGLAFHAKRSYQPHGRWAERAGQEPLKTILDAQDLDCYFTPMKPESLENSILD 900
LGDDDVADGLAFHAKRSYQPHGRWAERAGQEPLKTILDAQDLDCYFTPMKPESLENSILD
Sbjct: 841 LGDDDVADGLAFHAKRSYQPHGRWAERAGQEPLKTILDAQDLDCYFTPMKPESLENSILD 900
Query: 901 SLEPQSLASLLSESESPQEAGRGHPSFLPQQKESSEASELILYSLEAEVTVTGTDSQYCR 960
SLEPQSLASLLSESESPQEAGRGHPSFLPQQKESSEASELILYSLEAEVTVTGTDSQYCR
Sbjct: 901 SLEPQSLASLLSESESPQEAGRGHPSFLPQQKESSEASELILYSLEAEVTVTGTDSQYCR 960
Query: 961 KEVEAGPGDQQGDSYLRVSSDSPKDQSPPEDSGESEADLECSFAAIHSPAPPPDPAPRFA 1020
KEVEAGPGDQQGDSYLRVSSDSPKDQSPPEDSGESEADLECSFAAIHSPAPPPDPAPRFA
Sbjct: 961 KEVEAGPGDQQGDSYLRVSSDSPKDQSPPEDSGESEADLECSFAAIHSPAPPPDPAPRFA 1020
Query: 1021 TSLPHFPGCAGPTEDELSLPEGPSVPSSSLPQTPEQEKFLRHHFETLTESPCR-----AL 1075
TSLPHFPGCAGPTEDELSLPEGPSVPSSSLPQTPEQEKFLRHHFETLTESPCR AL
Sbjct: 1021 TSLPHFPGCAGPTEDELSLPEGPSVPSSSLPQTPEQEKFLRHHFETLTESPCRELFPAAL 1080
Query: 1076 GDVEASEAEDHFFNPRLSISTQFLSSLQKASRFTHTFPPRATQCLVKSPEVKLMDRGGSQ 1135
GDVEASEAEDHFFNPRLSISTQFLSSLQKASRFTHTFPPRATQCLVKSPEVKLMDRGGSQ
Sbjct: 1081 GDVEASEAEDHFFNPRLSISTQFLSSLQKASRFTHTFPPRATQCLVKSPEVKLMDRGGSQ 1140
Query: 1136 PRAGTGYASPDRTHVLAAGKAEETLEAWRPPPPCLTSLASCVPASSVLPTDRNLPTPTSA 1195
PRAGTGYASPDRTHVLAAGKAEETLEAWRPPPPCLTSLASCVPASSVLPTDRNLPTPTSA
Sbjct: 1141 PRAGTGYASPDRTHVLAAGKAEETLEAWRPPPPCLTSLASCVPASSVLPTDRNLPTPTSA 1200
Query: 1196 PTPGLAQGVHAPSTCSYMEATASSRARISRSISLGDSEGPIVATLAQPLRRPSSVGELAS 1255
PTPGLAQGVHAPSTCSYMEATASSRARISRSISLGDSEGPIVATLAQPLRRPSSVGELAS
Sbjct: 1201 PTPGLAQGVHAPSTCSYMEATASSRARISRSISLGDSEGPIVATLAQPLRRPSSVGELAS 1260
Query: 1256 LGQELQAITTATTPSLDSEGQEPALRSWGNHEARANLRLTLSSACDGLLQPPVDTQPGVT 1315
LGQELQAITTATTPSLDSEGQEPALRSWGNHEARANLRLTLSSACDGLLQPPVDTQPGVT
Sbjct: 1261 LGQELQAITTATTPSLDSEGQEPALRSWGNHEARANLRLTLSSACDGLLQPPVDTQPGVT 1320
Query: 1316 VPAVSFPAPSPVEESALRLHGSAFRPSLPAPESPGLPAHPSNPQLPEARPGIPGGTASLL 1375
VPAVSFPAPSPVEESALRLHGSAFRPSLPAPESPGLPAHPSNPQLPEARPGIPGGTASLL
Sbjct: 1321 VPAVSFPAPSPVEESALRLHGSAFRPSLPAPESPGLPAHPSNPQLPEARPGIPGGTASLL 1380
Query: 1376 EPTSGALGLLQGSPARWSEPWVPVEALPPSPLELSRVGNILHRLQTTFQEALDLYRVLVS 1435
EPTSGALGLLQGSPARWSEPWVPVEALPPSPLELSRVGNILHRLQTTFQEALDLYRVLVS
Sbjct: 1381 EPTSGALGLLQGSPARWSEPWVPVEALPPSPLELSRVGNILHRLQTTFQEALDLYRVLVS 1440
Query: 1436 SGQVDTGQQQARTELVSTFLWIHSQLEAECLVGTSVAPAQALPSPGPPSPPTLYPLASPD 1495
SGQVDTGQQQARTELVSTFLWIHSQLEAECLVGTSVAPAQALPSPGPPSPPTLYPLASPD
Sbjct: 1441 SGQVDTGQQQARTELVSTFLWIHSQLEAECLVGTSVAPAQALPSPGPPSPPTLYPLASPD 1500
Query: 1496 LQALLEHYSELLVQAVRRKARGH 1518
LQALLEHYSELLVQAVRRKARGH
Sbjct: 1501 LQALLEHYSELLVQAVRRKARGH 1523
>gi|190684671 mitogen-activated protein kinase binding protein 1
isoform a [Homo sapiens]
Length = 1508
Score = 1033 bits (2672), Expect = 0.0
Identities = 646/1565 (41%), Positives = 894/1565 (57%), Gaps = 166/1565 (10%)
Query: 37 APPICLRRRTRLSTASEETVQNRVSLEKVLGITAQNSSGLTCDPGTGHVAYLAGCVVVIL 96
+P I LRR + E + ++V+LEKVLGIT GL CDP +G VAY AGCVVV+
Sbjct: 18 SPSIKLRRSK--AGNRREDLSSKVTLEKVLGITVSGGRGLACDPRSGLVAYPAGCVVVLF 75
Query: 97 DPKENKQQHIFNTARKSLSALAFSPDGKYIVTGENGHRPAVRIWDVEEKNQVAEMLGHKY 156
+P+++KQ HI N++RK+++ALAFSPDGKY+VTGE+GH PAVR+WDV E +QVAE+ HKY
Sbjct: 76 NPRKHKQHHILNSSRKTITALAFSPDGKYLVTGESGHMPAVRVWDVAEHSQVAELQEHKY 135
Query: 157 GVACVAFSPNMKHIVSMGYQHDMVLNVWDWKKDIVVASNKVSCRVIALSFSEDSSYFVTV 216
GVACVAFSP+ K+IVS+GYQHDM++NVW WKK+IVVASNKVS RV A+SFSED SYFVT
Sbjct: 136 GVACVAFSPSAKYIVSVGYQHDMIVNVWAWKKNIVVASNKVSSRVTAVSFSEDCSYFVTA 195
Query: 217 GNRHVRFWFLEVSTETKVTSTVPLVGRSGILGELHNNIFCGVACGRGRMAGSTFCVSYSG 276
GNRH++FW+L+ S +KV +TVPL+GRSG+LGEL NN+F VACGRG+ A STFC++ SG
Sbjct: 196 GNRHIKFWYLDDSKTSKVNATVPLLGRSGLLGELRNNLFTDVACGRGKKADSTFCITSSG 255
Query: 277 LLCQFNEKRVLEKWINLKVSLSSCLCVSQELIFCGCTDGIVRIFQAHSLHYLANLPKPHY 336
LLC+F+++R+L+KW+ L+ +++ C+ VSQ+ IFCGC DG VR+F +LH+L+ LP+PH
Sbjct: 256 LLCEFSDRRLLDKWVELRTTVAHCISVSQDYIFCGCADGTVRLFNPSNLHFLSTLPRPHA 315
Query: 337 LGVDVAQGLEPSFLFHRKAEAVYPDTVALTFDPIHQWLSCVYKDHSIYIWDVKDINRVGK 396
LG D+A E S LF A A YPDT+ALTFDP +QWLSCVY DHSIY+WDV+D +VGK
Sbjct: 316 LGTDIASVTEASRLFSGVANARYPDTIALTFDPTNQWLSCVYNDHSIYVWDVRDPKKVGK 375
Query: 397 VWSELFHSSYVWNVEVYPEFEDQ-RACLPSGSFLTCSSDNTIRFWNLDSSP--DSHWQKN 453
V+S L+HSS VW+VEVYPE +D +ACLP SF+TCSSDNTIR WN +SS S +N
Sbjct: 376 VYSALYHSSCVWSVEVYPEVKDSNQACLPPSSFITCSSDNTIRLWNTESSGVHGSTLHRN 435
Query: 454 IFSNTLLKVVYVENDIQHLQDMSHFPDRGSENGTPMDVKAGVRVMQVSPDGQHLASGDRS 513
I S+ L+K++YV+ + Q L D + P + + +D + G+R + VSP+GQHLASGDR
Sbjct: 436 ILSSDLIKIIYVDGNTQALLD-TELPGGDKADASLLDPRVGIRSVCVSPNGQHLASGDRM 494
Query: 514 GNLRIHELHFMDELVKVEAHDAEVLCLEYSKPETGLTLLASASRDRLIHVLNVEKNYNLE 573
G LR+HEL + E++KVEAHD+E+LCLEYSKP+TGL LLASASRDRLIHVL+ + Y+L+
Sbjct: 495 GTLRVHELQSLSEMLKVEAHDSEILCLEYSKPDTGLKLLASASRDRLIHVLDAGREYSLQ 554
Query: 574 QTLDDHSSSITAIKFAGNR-DIQMISCGADKSIYFRSAQQGSDGLHFVRTHHVAEKTTLY 632
QTLD+HSSSITA+KFA + ++MISCGADKSIYFR+AQ+ DG+ F RTHHV KTTLY
Sbjct: 555 QTLDEHSSSITAVKFAASDGQVRMISCGADKSIYFRTAQKSGDGVQFTRTHHVVRKTTLY 614
Query: 633 DMDIDITQKYVAVACQDRNVRVYNTVNGKQKKCYKGSQGDEGSLLKVHVDPSGTFLATSC 692
DMD++ + KY A+ CQDRN+R++N +GKQKK +KGSQG++G+L+KV DPSG ++ATSC
Sbjct: 615 DMDVEPSWKYTAIGCQDRNIRIFNISSGKQKKLFKGSQGEDGTLIKVQTDPSGIYIATSC 674
Query: 693 SDKSISVIDFYSGECIAKMFGHSEIITSMKFTYDCHHLITVSGDSCVFIWHLGPEITNCM 752
SDK++S+ DF SGEC+A MFGHSEI+T MKF+ DC HLI+VSGDSC+F+W L E+T M
Sbjct: 675 SDKNLSIFDFSSGECVATMFGHSEIVTGMKFSNDCKHLISVSGDSCIFVWRLSSEMTISM 734
Query: 753 KQHLLEIDHRQQ---QQHTNDKKRSGHPRQD---TYVSTPSEIHSLSPGEQTEDDLEEEC 806
+Q L E+ RQ+ QQ + +R+ P + + +S + S S E ++ EEE
Sbjct: 735 RQRLAELRQRQRGGKQQGPSSPQRASGPNRHQAPSMLSPGPALSSDSDKEGEDEGTEEEL 794
Query: 807 EPEEMLKTPSKDSLDPDPRCLLTNGKLPLW----AKRLLGDDDVADGLAFHAKRSYQPHG 862
+L +K +L P L L W A+ +G D A A + G
Sbjct: 795 PALPVLAKSTKKALASVPSPALPRS-LSHWEMSRAQESVGFLDPAPA----ANPGPRRRG 849
Query: 863 RWAERAGQEPLKTILDAQDLDCYFTPMKPESLENSILDSLEPQSLA------SLLSESES 916
RW + + ++++LD + L+ ++ S ++ + P+ SL S++E
Sbjct: 850 RWVQPGVELSVRSMLDLRQLETLAPSLQDPSQDSLAIIPSGPRKHGQEALETSLTSQNEK 909
Query: 917 PQEAGRGHPSFLPQ------QKESSEASEL--------ILYSLEAEVTVTGTDSQYCRKE 962
P P P Q+E A +L I+Y E T S++ +
Sbjct: 910 PPRPQASQPCSYPHIIRLLSQEEGVFAQDLEPAPIEDGIVYP-EPSDNPTMDTSEF---Q 965
Query: 963 VEAGPGDQQGDSYLRVSSDSPKDQSPPEDSGESEADLECSFAAIHSPAPPPDPAPRFA-- 1020
V+A G Y P +S + S +S ++ S + + SP P + +
Sbjct: 966 VQAPARGTLGRVY-------PGSRSSEKHSPDSACSVDYSSSCLSSPEHPTEDSESTEPL 1018
Query: 1021 -----TSLPHFPGCAGPTEDELSLPEGPSVPSSSLPQTPEQEKFLRHHFETLTE--SPCR 1073
+S P E+E GP PQTP+QE+FL+ HFETL +P
Sbjct: 1019 SVDGISSDLEEPAEGDEEEEEEEGGMGPYGLQEGSPQTPDQEQFLKQHFETLASGAAPGA 1078
Query: 1074 ALGDVEASEAEDHFFNPRLSISTQFLSSLQKASRFTHTFPPRATQCLVKSPEVKLMDRGG 1133
+ E SE+ SIS++FL LQ +R P ++ + S ++ G
Sbjct: 1079 PVQVPERSESR--------SISSRFL--LQVQTRPLREPSPSSSSLALMSRPAQVPQASG 1128
Query: 1134 SQPRAG--------------TGYASPDRTHVLAAGKAEETLEA-WRPPPPCLTS----LA 1174
QPR +G SP + + + ++ W P S L
Sbjct: 1129 EQPRGNGANPPGAPPEVEPSSGNPSPQQAASVLLPRCRLNPDSSWAPKRVATASPFSGLQ 1188
Query: 1175 SCVPASSVLPTDRNLPTPTSAPTPG--LAQGVHAPSTC--------------SYMEATAS 1218
S++P +R+ AP+PG L++ + A SY T S
Sbjct: 1189 KAQSVHSLVPQERH-EASLQAPSPGALLSREIEAQDGLGSLPPADGRPSRPHSYQNPTTS 1247
Query: 1219 SRARISRSISLGDSEGPIVATLAQPLRRPSSVGELASLGQELQAITTATTPSLDSEGQEP 1278
S A+ISRSIS+G++ G + A R S + +LA L + P D P
Sbjct: 1248 SMAKISRSISVGENLGLVAEPQAHAPIRVSPLSKLA-LPSRAHLVLDIPKPLPD----RP 1302
Query: 1279 ALRSWGNHEARANLRLTLSSACDGLLQPPVDTQPGVTVPAVSFPAPSPVEESALRLHGSA 1338
L ++ +T A P +PG P A S E A G+
Sbjct: 1303 TLAAFSP--------VTKGRA------PGEAEKPGF--PVGLGKAHSTTERWACLGEGTT 1346
Query: 1339 FRPSLPAPESPGLPAHPSNPQLPEA---------RPGIPGGTASLLEPTSGALGLLQGSP 1389
+P PG P+ P QLP + +P P T + +E T L Q S
Sbjct: 1347 PKPRTECQAHPG-PSSPCAQQLPVSSLFQGPENLQPPPPEKTPNPMECTKPGAALSQDS- 1404
Query: 1390 ARWSEPWVPVEALPPSPLELSRVGNILHRLQTTFQEALDLYRVLVSSGQVDTGQQQARTE 1449
EP V +E + ++ L+ + ++A+ LY + Q +
Sbjct: 1405 ----EPAVSLE----------QCEQLVAELRGSVRQAVRLYHSVAGCKMPSAEQSRIAQL 1450
Query: 1450 LVSTFLWIHSQLEAECLVGTSVAPAQALPSPGPPSPPTLYPLASPDLQALLEHYSELLVQ 1509
L TF + +LEA VA A L SPG SP + + QALLE YSELL++
Sbjct: 1451 LRDTFSSVRQELEA-------VAGA-VLSSPGS-SPGAV---GAEQTQALLEQYSELLLR 1498
Query: 1510 AVRRK 1514
AV R+
Sbjct: 1499 AVERR 1503
>gi|190684677 mitogen-activated protein kinase binding protein 1
isoform b [Homo sapiens]
Length = 1514
Score = 1027 bits (2655), Expect = 0.0
Identities = 646/1571 (41%), Positives = 894/1571 (56%), Gaps = 172/1571 (10%)
Query: 37 APPICLRRRTRLSTASEETVQNRVSLEKVLGITAQNSSGLTCDPGTGHVAYLAGCVVVIL 96
+P I LRR + E + ++V+LEKVLGIT GL CDP +G VAY AGCVVV+
Sbjct: 18 SPSIKLRRSK--AGNRREDLSSKVTLEKVLGITVSGGRGLACDPRSGLVAYPAGCVVVLF 75
Query: 97 DPKENKQQHIFNTARKSLSALAFSPDGKYIVTGENGHRPAVRIWDVEEKNQVAEMLGHKY 156
+P+++KQ HI N++RK+++ALAFSPDGKY+VTGE+GH PAVR+WDV E +QVAE+ HKY
Sbjct: 76 NPRKHKQHHILNSSRKTITALAFSPDGKYLVTGESGHMPAVRVWDVAEHSQVAELQEHKY 135
Query: 157 GVACVAFSPNMKHIVSMGYQHDMVLNVWDWKKDIVVASNKVSCRVIALSFSEDSSYFVTV 216
GVACVAFSP+ K+IVS+GYQHDM++NVW WKK+IVVASNKVS RV A+SFSED SYFVT
Sbjct: 136 GVACVAFSPSAKYIVSVGYQHDMIVNVWAWKKNIVVASNKVSSRVTAVSFSEDCSYFVTA 195
Query: 217 GNRHVRFWFLEVSTETKVTSTVPLVGRSGILGELHNNIFCGVACGRGRMAGSTFCVSYSG 276
GNRH++FW+L+ S +KV +TVPL+GRSG+LGEL NN+F VACGRG+ A STFC++ SG
Sbjct: 196 GNRHIKFWYLDDSKTSKVNATVPLLGRSGLLGELRNNLFTDVACGRGKKADSTFCITSSG 255
Query: 277 LLCQFNEKRVLEKWINLK------VSLSSCLCVSQELIFCGCTDGIVRIFQAHSLHYLAN 330
LLC+F+++R+L+KW+ L+ +++ C+ VSQ+ IFCGC DG VR+F +LH+L+
Sbjct: 256 LLCEFSDRRLLDKWVELRNIDSFTTTVAHCISVSQDYIFCGCADGTVRLFNPSNLHFLST 315
Query: 331 LPKPHYLGVDVAQGLEPSFLFHRKAEAVYPDTVALTFDPIHQWLSCVYKDHSIYIWDVKD 390
LP+PH LG D+A E S LF A A YPDT+ALTFDP +QWLSCVY DHSIY+WDV+D
Sbjct: 316 LPRPHALGTDIASVTEASRLFSGVANARYPDTIALTFDPTNQWLSCVYNDHSIYVWDVRD 375
Query: 391 INRVGKVWSELFHSSYVWNVEVYPEFEDQ-RACLPSGSFLTCSSDNTIRFWNLDSSP--D 447
+VGKV+S L+HSS VW+VEVYPE +D +ACLP SF+TCSSDNTIR WN +SS
Sbjct: 376 PKKVGKVYSALYHSSCVWSVEVYPEVKDSNQACLPPSSFITCSSDNTIRLWNTESSGVHG 435
Query: 448 SHWQKNIFSNTLLKVVYVENDIQHLQDMSHFPDRGSENGTPMDVKAGVRVMQVSPDGQHL 507
S +NI S+ L+K++YV+ + Q L D + P + + +D + G+R + VSP+GQHL
Sbjct: 436 STLHRNILSSDLIKIIYVDGNTQALLD-TELPGGDKADASLLDPRVGIRSVCVSPNGQHL 494
Query: 508 ASGDRSGNLRIHELHFMDELVKVEAHDAEVLCLEYSKPETGLTLLASASRDRLIHVLNVE 567
ASGDR G LR+HEL + E++KVEAHD+E+LCLEYSKP+TGL LLASASRDRLIHVL+
Sbjct: 495 ASGDRMGTLRVHELQSLSEMLKVEAHDSEILCLEYSKPDTGLKLLASASRDRLIHVLDAG 554
Query: 568 KNYNLEQTLDDHSSSITAIKFAGNR-DIQMISCGADKSIYFRSAQQGSDGLHFVRTHHVA 626
+ Y+L+QTLD+HSSSITA+KFA + ++MISCGADKSIYFR+AQ+ DG+ F RTHHV
Sbjct: 555 REYSLQQTLDEHSSSITAVKFAASDGQVRMISCGADKSIYFRTAQKSGDGVQFTRTHHVV 614
Query: 627 EKTTLYDMDIDITQKYVAVACQDRNVRVYNTVNGKQKKCYKGSQGDEGSLLKVHVDPSGT 686
KTTLYDMD++ + KY A+ CQDRN+R++N +GKQKK +KGSQG++G+L+KV DPSG
Sbjct: 615 RKTTLYDMDVEPSWKYTAIGCQDRNIRIFNISSGKQKKLFKGSQGEDGTLIKVQTDPSGI 674
Query: 687 FLATSCSDKSISVIDFYSGECIAKMFGHSEIITSMKFTYDCHHLITVSGDSCVFIWHLGP 746
++ATSCSDK++S+ DF SGEC+A MFGHSEI+T MKF+ DC HLI+VSGDSC+F+W L
Sbjct: 675 YIATSCSDKNLSIFDFSSGECVATMFGHSEIVTGMKFSNDCKHLISVSGDSCIFVWRLSS 734
Query: 747 EITNCMKQHLLEIDHRQQ---QQHTNDKKRSGHPRQD---TYVSTPSEIHSLSPGEQTED 800
E+T M+Q L E+ RQ+ QQ + +R+ P + + +S + S S E ++
Sbjct: 735 EMTISMRQRLAELRQRQRGGKQQGPSSPQRASGPNRHQAPSMLSPGPALSSDSDKEGEDE 794
Query: 801 DLEEECEPEEMLKTPSKDSLDPDPRCLLTNGKLPLW----AKRLLGDDDVADGLAFHAKR 856
EEE +L +K +L P L L W A+ +G D A A
Sbjct: 795 GTEEELPALPVLAKSTKKALASVPSPALPRS-LSHWEMSRAQESVGFLDPAPA----ANP 849
Query: 857 SYQPHGRWAERAGQEPLKTILDAQDLDCYFTPMKPESLENSILDSLEPQSLA------SL 910
+ GRW + + ++++LD + L+ ++ S ++ + P+ SL
Sbjct: 850 GPRRRGRWVQPGVELSVRSMLDLRQLETLAPSLQDPSQDSLAIIPSGPRKHGQEALETSL 909
Query: 911 LSESESPQEAGRGHPSFLPQ------QKESSEASEL--------ILYSLEAEVTVTGTDS 956
S++E P P P Q+E A +L I+Y E T S
Sbjct: 910 TSQNEKPPRPQASQPCSYPHIIRLLSQEEGVFAQDLEPAPIEDGIVYP-EPSDNPTMDTS 968
Query: 957 QYCRKEVEAGPGDQQGDSYLRVSSDSPKDQSPPEDSGESEADLECSFAAIHSPAPPPDPA 1016
++ +V+A G Y P +S + S +S ++ S + + SP P + +
Sbjct: 969 EF---QVQAPARGTLGRVY-------PGSRSSEKHSPDSACSVDYSSSCLSSPEHPTEDS 1018
Query: 1017 PRFA-------TSLPHFPGCAGPTEDELSLPEGPSVPSSSLPQTPEQEKFLRHHFETLTE 1069
+S P E+E GP PQTP+QE+FL+ HFETL
Sbjct: 1019 ESTEPLSVDGISSDLEEPAEGDEEEEEEEGGMGPYGLQEGSPQTPDQEQFLKQHFETLAS 1078
Query: 1070 --SPCRALGDVEASEAEDHFFNPRLSISTQFLSSLQKASRFTHTFPPRATQCLVKSPEVK 1127
+P + E SE+ SIS++FL LQ +R P ++ + S +
Sbjct: 1079 GAAPGAPVQVPERSESR--------SISSRFL--LQVQTRPLREPSPSSSSLALMSRPAQ 1128
Query: 1128 LMDRGGSQPRAG--------------TGYASPDRTHVLAAGKAEETLEA-WRPPPPCLTS 1172
+ G QPR +G SP + + + ++ W P S
Sbjct: 1129 VPQASGEQPRGNGANPPGAPPEVEPSSGNPSPQQAASVLLPRCRLNPDSSWAPKRVATAS 1188
Query: 1173 ----LASCVPASSVLPTDRNLPTPTSAPTPG--LAQGVHAPSTC--------------SY 1212
L S++P +R+ AP+PG L++ + A SY
Sbjct: 1189 PFSGLQKAQSVHSLVPQERH-EASLQAPSPGALLSREIEAQDGLGSLPPADGRPSRPHSY 1247
Query: 1213 MEATASSRARISRSISLGDSEGPIVATLAQPLRRPSSVGELASLGQELQAITTATTPSLD 1272
T SS A+ISRSIS+G++ G + A R S + +LA L + P D
Sbjct: 1248 QNPTTSSMAKISRSISVGENLGLVAEPQAHAPIRVSPLSKLA-LPSRAHLVLDIPKPLPD 1306
Query: 1273 SEGQEPALRSWGNHEARANLRLTLSSACDGLLQPPVDTQPGVTVPAVSFPAPSPVEESAL 1332
P L ++ +T A P +PG P A S E A
Sbjct: 1307 ----RPTLAAFSP--------VTKGRA------PGEAEKPGF--PVGLGKAHSTTERWAC 1346
Query: 1333 RLHGSAFRPSLPAPESPGLPAHPSNPQLPEA---------RPGIPGGTASLLEPTSGALG 1383
G+ +P PG P+ P QLP + +P P T + +E T
Sbjct: 1347 LGEGTTPKPRTECQAHPG-PSSPCAQQLPVSSLFQGPENLQPPPPEKTPNPMECTKPGAA 1405
Query: 1384 LLQGSPARWSEPWVPVEALPPSPLELSRVGNILHRLQTTFQEALDLYRVLVSSGQVDTGQ 1443
L Q S EP V +E + ++ L+ + ++A+ LY + Q
Sbjct: 1406 LSQDS-----EPAVSLE----------QCEQLVAELRGSVRQAVRLYHSVAGCKMPSAEQ 1450
Query: 1444 QQARTELVSTFLWIHSQLEAECLVGTSVAPAQALPSPGPPSPPTLYPLASPDLQALLEHY 1503
+ L TF + +LEA VA A L SPG SP + + QALLE Y
Sbjct: 1451 SRIAQLLRDTFSSVRQELEA-------VAGA-VLSSPGS-SPGAV---GAEQTQALLEQY 1498
Query: 1504 SELLVQAVRRK 1514
SELL++AV R+
Sbjct: 1499 SELLLRAVERR 1509
>gi|124028512 WD40-repeat protein upregulated in HCC isoform b [Homo
sapiens]
Length = 620
Score = 81.6 bits (200), Expect = 5e-15
Identities = 55/186 (29%), Positives = 88/186 (47%), Gaps = 11/186 (5%)
Query: 52 SEETVQNRVSLEKVLGITAQNSSGLTCDPGTGHVAYLAGCVVVILDPKENKQQHIFNTAR 111
S E + L+ V+G +GL C P H+ Y GC V+I K+Q+
Sbjct: 6 SPEAQVAELELDAVIGFNGHVPTGLKCHPDQEHMIYPLGCTVLI-QAINTKEQNFLQGHG 64
Query: 112 KSLSALAFSPDGKYIVTGE---NGHRPAVRIWDVEEKNQVAEMLGHKYGVACVAFSPNMK 168
++S LA S G+YI +G+ G + + +WD + + +A + HK + +AFSPN
Sbjct: 65 NNVSCLAISRSGEYIASGQVTFMGFKADIILWDYKNRELLARLSLHKGKIEALAFSPNDL 124
Query: 169 HIVSMGYQHDMVLNVWD-WKKDIVVASNKVSCRV-----IALSFSEDSSYFVTVGNRHVR 222
++VS+G D + VW K+D + S V + S D F+T GN +R
Sbjct: 125 YLVSLGGPDDGSVVVWSIAKRDAICGSPAAGLNVGNATNVIFSRCRD-EMFMTAGNGTIR 183
Query: 223 FWFLEV 228
W L++
Sbjct: 184 VWELDL 189
Score = 44.7 bits (104), Expect = 7e-04
Identities = 35/171 (20%), Positives = 70/171 (40%), Gaps = 9/171 (5%)
Query: 572 LEQTLDDHSSSITAIKFAGNRDIQMISCGADKSIYFRSAQQGSDGLHFVRTHHVAEKTTL 631
LE+ L +H SS++ I+ N + + ++ D + D + R + T
Sbjct: 453 LEEALKEHKSSVSCIRVKRNNE-ECVTASTDGTCIIW------DLVRLRRNQMILANTLF 505
Query: 632 YDMDIDITQKYVAVACQDRNVRVYNTVNGKQKKCYKGSQGDEGSLLKVHVDPSGTFLATS 691
+ + + + DR + + +G + +GS GS+ + + G T
Sbjct: 506 QCVCYHPEEFQIITSGTDRKIAYWEVFDGTVIRELEGSLS--GSINGMDITQEGVHFVTG 563
Query: 692 CSDKSISVIDFYSGECIAKMFGHSEIITSMKFTYDCHHLITVSGDSCVFIW 742
+D + V D+ GE GHS IT ++ + ++++VS D + W
Sbjct: 564 GNDHLVKVWDYNEGEVTHVGVGHSGNITRIRISPGNQYIVSVSADGAILRW 614
Score = 37.4 bits (85), Expect = 0.11
Identities = 18/61 (29%), Positives = 32/61 (52%), Gaps = 2/61 (3%)
Query: 113 SLSALAFSPDGKYIVTGENGHRPAVRIWDVEEKNQVAEMLGHKYGVACVAFSPNMKHIVS 172
S++ + + +G + VTG N H V++WD E +GH + + SP ++IVS
Sbjct: 547 SINGMDITQEGVHFVTGGNDH--LVKVWDYNEGEVTHVGVGHSGNITRIRISPGNQYIVS 604
Query: 173 M 173
+
Sbjct: 605 V 605
>gi|32189425 WD repeat domain 69 [Homo sapiens]
Length = 415
Score = 81.3 bits (199), Expect = 7e-15
Identities = 64/251 (25%), Positives = 113/251 (45%), Gaps = 15/251 (5%)
Query: 493 AGVRVMQVSPDGQHLASGDRSGNLRIHELHFMDELVKVEAHDAEVLCLEYSKPETGLTLL 552
A + + +P +A+G ++ ++ +E+ + H AE++ L ++ T +
Sbjct: 178 AEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSFN---TSGDRI 234
Query: 553 ASASRDRLIHVLNVEKNYNLEQTLDDHSSSITAIKFAGNRDIQMISCGA-DKSIYFRSAQ 611
+ S D + V + + + L H + I++ F N D +I G+ DK+ A
Sbjct: 235 ITGSFDHTVVVWDADTGRKVN-ILIGHCAEISSASF--NWDCSLILTGSMDKTCKLWDAT 291
Query: 612 QGSDGLHFVRTHHVAEKTTLYDMDIDITQKYVAVACQDRNVRVYNTVNGKQKKCYKGSQG 671
G T H E + D D T K +A A D R+++ +KC +G
Sbjct: 292 NGK--CVATLTGHDDE---ILDSCFDYTGKLIATASADGTARIFSAAT---RKCIAKLEG 343
Query: 672 DEGSLLKVHVDPSGTFLATSCSDKSISVIDFYSGECIAKMFGHSEIITSMKFTYDCHHLI 731
EG + K+ +P G L T SDK+ + D +G+C+ + GH++ I S F Y + +I
Sbjct: 344 HEGEISKISFNPQGNHLLTGSSDKTARIWDAQTGQCLQVLEGHTDEIFSCAFNYKGNIVI 403
Query: 732 TVSGDSCVFIW 742
T S D+ IW
Sbjct: 404 TGSKDNTCRIW 414
Score = 48.9 bits (115), Expect = 4e-05
Identities = 27/100 (27%), Positives = 47/100 (47%), Gaps = 3/100 (3%)
Query: 643 VAVACQDRNVRVYNTVNGKQKKCYKGSQGDEGSLLKVHVDPSGTFLATSCSDKSISVIDF 702
+A D+ ++++ GK CY +G ++ + +P T +AT D + + D
Sbjct: 150 IATGSFDKTCKLWSVETGK---CYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDI 206
Query: 703 YSGECIAKMFGHSEIITSMKFTYDCHHLITVSGDSCVFIW 742
+GE + + GHS I S+ F +IT S D V +W
Sbjct: 207 QNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVW 246
Score = 40.8 bits (94), Expect = 0.010
Identities = 27/118 (22%), Positives = 53/118 (44%), Gaps = 11/118 (9%)
Query: 102 KQQHIFNTARKSLSALAFSPDGKYIVTGENGHRPAVRIWDVEEKNQVAEMLGHKYGVACV 161
K H F + L+F+P + TG ++WD++ +V + GH + +
Sbjct: 168 KCYHTFRGHTAEIVCLSFNPQSTLVATGSMD--TTAKLWDIQNGEEVYTLRGHSAEIISL 225
Query: 162 AFSPNMKHIVSMGYQHDMVLNVWD----WKKDIVVASNKVSCRVIALSFSEDSSYFVT 215
+F+ + I++ + H +V VWD K +I++ + + SF+ D S +T
Sbjct: 226 SFNTSGDRIITGSFDHTVV--VWDADTGRKVNILIGH---CAEISSASFNWDCSLILT 278
Score = 40.4 bits (93), Expect = 0.013
Identities = 56/238 (23%), Positives = 90/238 (37%), Gaps = 19/238 (7%)
Query: 97 DPKENKQQHIFNTARKSLSALAFS-PDGKYIVTGENGHRPAVRIWDVEEKNQVAEMLGHK 155
D ++ + R + A+AF+ P G I TG ++W VE GH
Sbjct: 120 DTASGEELNTLEGHRNVVYAIAFNNPYGDKIATGS--FDKTCKLWSVETGKCYHTFRGHT 177
Query: 156 YGVACVAFSPNMKHIVSMGYQHDMVLNVWDWKK-DIVVASNKVSCRVIALSFSEDSSYFV 214
+ C++F+P +V+ G D +WD + + V S +I+LSF+ +
Sbjct: 178 AEIVCLSFNPQST-LVATGSM-DTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTSGDRII 235
Query: 215 TVGNRH-VRFWFLEVSTETKVTSTVPLVGRSGILGELHNNIFCGVACGRGRMAGSTFCVS 273
T H V W + + + L+G + N C + G M + C
Sbjct: 236 TGSFDHTVVVWDADTGRKVNI-----LIGHCAEISSASFNWDCSLIL-TGSMDKT--CKL 287
Query: 274 YSGLLCQFNEKRVLEKWINLKVSLSSCLCVSQELIFCGCTDGIVRIFQAHSLHYLANL 331
+ N K V + L SC + +LI DG RIF A + +A L
Sbjct: 288 WDAT----NGKCVATLTGHDDEILDSCFDYTGKLIATASADGTARIFSAATRKCIAKL 341
Score = 35.0 bits (79), Expect = 0.55
Identities = 26/113 (23%), Positives = 52/113 (46%), Gaps = 5/113 (4%)
Query: 649 DRNVRVYNTVNGKQKKCYKGSQGDEGSLLKVHVDPSGTFLATSCSDKSISVIDFYSGECI 708
DR ++++T +G++ +G + ++ +P G +AT DK+ + +G+C
Sbjct: 113 DRTCKLWDTASGEELNTLEGHRNVVYAI--AFNNPYGDKIATGSFDKTCKLWSVETGKCY 170
Query: 709 AKMFGHSEIITSMKFTYDCHHLITVSGDSCVFIWHL--GPEITNCMKQHLLEI 759
GH+ I + F + T S D+ +W + G E+ ++ H EI
Sbjct: 171 HTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVYT-LRGHSAEI 222
Score = 32.0 bits (71), Expect = 4.7
Identities = 18/71 (25%), Positives = 33/71 (46%), Gaps = 4/71 (5%)
Query: 114 LSALAFSPDGKYIVTGENGHRPAVRIWDVEEKNQVAEMLGHKYGVACVAFSPNMKHIVSM 173
+S ++F+P G +++TG + RIWD + + + GH + AF N K + +
Sbjct: 348 ISKISFNPQGNHLLTGSSD--KTARIWDAQTGQCLQVLEGHTDEIFSCAF--NYKGNIVI 403
Query: 174 GYQHDMVLNVW 184
D +W
Sbjct: 404 TGSKDNTCRIW 414
>gi|34485720 echinoderm microtubule associated protein like 5 [Homo
sapiens]
Length = 1977
Score = 74.7 bits (182), Expect = 6e-13
Identities = 58/223 (26%), Positives = 97/223 (43%), Gaps = 19/223 (8%)
Query: 43 RRRTRLSTASEETVQNRVSLEKVLGITAQNSSGLTCDPGTGHVAYLAGCVVVILDPKENK 102
++++ S E N + L V G + G + Y V VI + ++N
Sbjct: 660 KQKSATSKRRERAPGNSIRLHFVHGYRGYDCRSNLFYTQIGEIVYHVAAVGVIYNRQQNT 719
Query: 103 QQHIFNTARKSLSALAFSPDGKYIVTGENGHRPAVRIWDVEEKNQVAEMLGH-KYGVACV 161
Q+ L L P Y+ TG+ G P++ IWD E ++ + GH +YGV+ V
Sbjct: 720 QRFYLGHDDDIL-CLTIHPLKDYVATGQVGRDPSIHIWDTETIKPLSILKGHHQYGVSAV 778
Query: 162 AFSPNMKHIVSMGYQHDMVLNVWDWKKD---IVVASNKVSCRVIALS-FSEDSSYFVTVG 217
FS + K + S+G + +WDWKK + +K V+ ++ + D +T G
Sbjct: 779 DFSADGKRLASVGIDDSHTVVLWDWKKGEKLSIARGSKDKIFVVKMNPYVPDK--LITAG 836
Query: 218 NRHVRFWFLEVSTETKVTSTVPLVGRSGILGELHNN--IFCGV 258
+H++FW + L+GR G +G L N + C V
Sbjct: 837 IKHMKFW---------RKAGGGLIGRKGYIGTLGKNDTMMCAV 870
Score = 70.9 bits (172), Expect = 9e-12
Identities = 63/246 (25%), Positives = 114/246 (46%), Gaps = 29/246 (11%)
Query: 85 VAYLAGCVVVILDPKENKQQHIFNTARKSLSALAFSPDGKYIVTGENGHRPAVRIWDVEE 144
+ Y V V+ P+E++Q+ + + +LA P+ + TG+ G P + IWD
Sbjct: 36 IVYFVAGVGVVYSPREHRQK-FYRGHSDDIISLALHPERVLVATGQVGKEPYICIWDSYT 94
Query: 145 KNQVAEMLG-HKYGVACVAFSPNMKHIVSMGYQHDMVLNVWDWKKDIVVA-SNKVSCRVI 202
++ + H +G+AC+AF + + +VS+G + VWDWK+ +++ + + R+
Sbjct: 95 VQTISVLKDVHTHGIACLAFDLDGQRLVSVGLDSKNAVCVWDWKRGKMLSMAPGHTDRIF 154
Query: 203 ALSFS-EDSSYFVTVGNRHVRFWFLEVSTETKVTSTVPLVGRSGILGELHNNIFCGVACG 261
+S+ + V+ G +H++FW L + T P G G G+L I C +AC
Sbjct: 155 DISWDLYQPNKLVSCGVKHIKFWSLCGNALT------PKRGVFGKTGDL-QTILC-LACA 206
Query: 262 RGRMAGSTFCVSYSGLLCQFNEKRVLEKWINLKVSLSSC-------LCVSQELIFCGCTD 314
R + +YSG L N + K INL ++ + +E G D
Sbjct: 207 RDEL-------TYSGAL---NGDIYVWKGINLIRTIQGAHAAGIFSMNACEEGFATGGRD 256
Query: 315 GIVRIF 320
G +R++
Sbjct: 257 GCIRLW 262
Score = 58.9 bits (141), Expect = 4e-08
Identities = 67/285 (23%), Positives = 115/285 (40%), Gaps = 30/285 (10%)
Query: 16 EKLPSVMAGVPARRGQSSPPP-APPICLRRRTRLSTASEETVQNRVSLEKVLGITAQNSS 74
+K PS+ RG P APP + +T + +++ V LE + G ++
Sbjct: 1327 QKEPSIDERQGVVRGSRPPVSRAPPQPEKLQTNNVGKKKRPIEDLV-LELIFGYRGRDCR 1385
Query: 75 GLTCDPGTGHVAYLAGCVVVILDPKENKQQHIFNTARKSLSALAFSPDGKYI---VTGEN 131
G V IL Q + + L + K+I TG+
Sbjct: 1386 NNVHYLNDGDDIIYHTASVGILHNVATGSQSFYQEHNDDILCLTVNQHPKFINIVATGQV 1445
Query: 132 GHR-------PAVRIWDVEEKNQVAEM-LGHKYGVACVAFSPNMKHIVSMGYQHDMVLNV 183
G P++ IWD K ++ + H GV V+FS K ++S+G + + +
Sbjct: 1446 GDSADMSATAPSIHIWDAMNKQTLSILRCYHSKGVCSVSFSATGKLLLSVGLDPEHTITI 1505
Query: 184 WDWKKDIVVASNK-VSCRVIALSFSEDS-SYFVTVGNRHVRFWFLEVSTETKVTSTVPLV 241
W W++ +AS + R+ F DS + FV+VG +HV+FW L + L+
Sbjct: 1506 WRWQEGAKIASRAGHNQRIFVAEFRPDSDTQFVSVGVKHVKFWTL---------AGRALL 1556
Query: 242 GRSGILGELHN---NIFCGVACGRGRMAGSTFCVSYSGLLCQFNE 283
+ G+L L + +A G + TF + SG +C + +
Sbjct: 1557 SKKGLLSTLEDARMQTMLAIAFGANNL---TFTGTISGDVCVWKD 1598
Score = 48.9 bits (115), Expect = 4e-05
Identities = 70/340 (20%), Positives = 135/340 (39%), Gaps = 47/340 (13%)
Query: 495 VRVMQVSPDGQHLASGDRSGNLRIHELHFMDELVKVEAHDAEVLCLEYSKPETGLTLLAS 554
+R V+ DG HLA G + G+ + + M E+V ++ + L+YS T LA
Sbjct: 369 IRCAAVNADGIHLALGMKDGSFTVLRVRDMTEVVHIKDRKEAIHELKYSPDG---TYLAV 425
Query: 555 ASRDRLIHVLNVEKNYNLEQTLDDHSSSITAIKFAGNRDIQMISCGADKSIYFR-SAQQG 613
D + + V + Y S IT + ++ + + G K +++R +
Sbjct: 426 GCNDSSVDIYGVAQRYKKVGECLGSLSFITHLDWSSDSRYLQTNDGNGKRLFYRMPGGKE 485
Query: 614 SDGLHFVRTHHVAEKTTLYDMDID-ITQKYVAVACQDRNVRVYNTVNGKQKKCYKGS--- 669
++ H A T + ++++ I KY ++ N+V+G Y G
Sbjct: 486 VTSTEEIKGVHWASWTCVSGLEVNGIWPKY-------SDINDINSVDGN----YIGQVLV 534
Query: 670 QGDEGSLLKVHVDPSGTFLATSCSDKSISVIDFYSGECIAKMFGHSEIITSMKFTYDCHH 729
D+ ++K+ P C K G K GHS +T++++++D
Sbjct: 535 TADDYGIIKLFRYP--------CLRK---------GAKFRKYIGHSAHVTNVRWSHDYQW 577
Query: 730 LITVSG-DSCVFIWHLGPE-----ITNCMKQHLLEIDHRQQQQHTNDKKRSGHPRQDTYV 783
+I++ G D VF W PE + Q L H + +D S P D+ +
Sbjct: 578 VISIGGADHSVFQWKFIPERKLKDAVHIAPQESLADSHSDE----SDSDLSDVPELDSEI 633
Query: 784 STPSEI-HSLSPGEQTEDDLEEECEPEEMLKTPSKDSLDP 822
+++ + ++ L+E+C+ ++ T + P
Sbjct: 634 EQETQLTYRRQVYKEDLPQLKEQCKEKQKSATSKRRERAP 673
Score = 39.3 bits (90), Expect = 0.029
Identities = 22/66 (33%), Positives = 33/66 (50%), Gaps = 4/66 (6%)
Query: 681 VDPSGTFLATSCSDKSISVIDFYSGECIAK---MFGHSEIITSMKFTYDCHHLITVSGDS 737
V SG L T + + DF E AK GHS +T+++FT H+++ GD
Sbjct: 1905 VSHSGISLVTGDDFGMVKLFDFPCPEKFAKHKRFLGHSPHVTNIRFTSGDRHVVSAGGDD 1964
Query: 738 C-VFIW 742
C +F+W
Sbjct: 1965 CSLFVW 1970
>gi|223005862 echinoderm microtubule associated protein like 6 [Homo
sapiens]
Length = 1958
Score = 72.0 bits (175), Expect = 4e-12
Identities = 64/246 (26%), Positives = 113/246 (45%), Gaps = 29/246 (11%)
Query: 85 VAYLAGCVVVILDPKENKQQHIFNTARKSLSALAFSPDGKYIVTGENGHRPAVRIWDVEE 144
V Y V V+ + +E+ Q+ F + +LA PD + TG+ G P + IWD
Sbjct: 36 VVYFVAGVGVVYNTREHSQK-FFLGHNDDIISLALHPDKTLVATGQVGKEPYICIWDSYN 94
Query: 145 KNQVAEMLG-HKYGVACVAFSPNMKHIVSMGYQHDMVLNVWDWKKDIVVAS-NKVSCRVI 202
V+ + H +GVAC+AF + + + S+G + +WDW+K ++AS S R+
Sbjct: 95 VQTVSLLKDVHTHGVACLAFDSDGQRLASVGLDAKNTVCIWDWRKGKLLASATGHSDRIF 154
Query: 203 ALSFSE-DSSYFVTVGNRHVRFWFLEVSTETKVTSTVPLVGRSGILGELHNNIFCGVACG 261
+S+ + V+ G +H++FW L +T+ + G++G L I C +AC
Sbjct: 155 DISWDPYQPNRVVSCGVKHIKFWTL---CGNALTAKRGIFGKTGDL----QTILC-LACA 206
Query: 262 RGRMAGSTFCVSYSGLLCQFNEKRVLEKWINLKVSLSSC-------LCVSQELIFCGCTD 314
+ ++YSG L N + K +NL ++ + +E G D
Sbjct: 207 KED-------ITYSGAL---NGDIYVWKGLNLVRTIQGAHSAGIFSMYACEEGFATGGRD 256
Query: 315 GIVRIF 320
G +R++
Sbjct: 257 GCIRLW 262
Score = 66.6 bits (161), Expect = 2e-10
Identities = 49/193 (25%), Positives = 84/193 (43%), Gaps = 21/193 (10%)
Query: 83 GHVAYLAGCVVVILDPKENKQQHIFNTARKSLSALAFSPDGKYIVTGENGHRPAVRIWDV 142
G V Y V V+ + +++ Q+ ++ + +L P Y+ TG+ G A+ +WD
Sbjct: 700 GEVVYHIAAVAVVYNRQQHSQR-LYLGHDDDILSLTIHPVKDYVATGQVGRDAAIHVWDT 758
Query: 143 EEKNQVAEMLG-HKYGVACVAFSPNMKHIVSMGYQHDMVLNVWDWKKDIVVASNK----- 196
+ ++ + G H+ GV + FS + K +VS+G + WDWKK +A+ +
Sbjct: 759 QTLKCLSLLKGQHQRGVCALDFSADGKCLVSVGLDDFHSIVFWDWKKGEKIATTRGHKDK 818
Query: 197 ---VSCRVIALSFSEDSSYFVTVGNRHVRFWFLEVSTETKVTSTVPLVGRSGIL-----G 248
V C VTVG +H++FW T T VG+ + G
Sbjct: 819 IFVVKCN------PHHVDKLVTVGIKHIKFWQQAGGGFTSKRGTFGSVGKLETMMCVSYG 872
Query: 249 ELHNNIFCGVACG 261
+ + +F G A G
Sbjct: 873 RMEDLVFSGAATG 885
Score = 61.6 bits (148), Expect = 6e-09
Identities = 39/128 (30%), Positives = 65/128 (50%), Gaps = 12/128 (9%)
Query: 126 IVTGENGHRPAVRIWDVEEKNQVAEM-LGHKYGVACVAFSPNMKHIVSMGYQHDMVLNVW 184
+ T + G P++ IWD K+ ++ + H GV + FS K +VS+G + + VW
Sbjct: 1432 VATSQIGTTPSIHIWDAMTKHTLSMLRCFHSKGVNYINFSATGKLLVSVGVDPEHTITVW 1491
Query: 185 DWKKDIVVASNKVSC-RVIALSFSEDS-SYFVTVGNRHVRFWFLEVSTETKVTSTVPLVG 242
W++ VAS R+ + F DS + FV+VG +H++FW L S L+
Sbjct: 1492 RWQEGAKVASRGGHLERIFVVEFRPDSDTQFVSVGVKHMKFWTLAGSA---------LLY 1542
Query: 243 RSGILGEL 250
+ G++G L
Sbjct: 1543 KKGVIGSL 1550
Score = 42.0 bits (97), Expect = 0.005
Identities = 58/267 (21%), Positives = 105/267 (39%), Gaps = 34/267 (12%)
Query: 502 PDGQHLASGDRSGNLRIHELHFMDELVKVEAHDAEVLCLEYSKPETGLTLLASASRDRLI 561
P S G RI +L L KV A C YS P+ + + + + +I
Sbjct: 1697 PSKDLFISASNDGTARIWDLADKKLLNKVSLGHA-ARCAAYS-PDGEMVAIGMKNGEFVI 1754
Query: 562 HVLNVEKNYNLEQTLDDHSSSITAIKFAGNRDIQMISCGADKSIYFRSAQQGSDGLHFVR 621
++N K + ++ D S+I I+ + + + ++ ++ F QG++
Sbjct: 1755 LLVNSLKVWGKKR---DRKSAIQDIRISPDNRFLAVG-SSEHTVDFYDLTQGTNLNRIGY 1810
Query: 622 THHVAEKTTLYDMDIDITQKYVAVACQDRNVRVYNTVNGKQ-------KKCYKGS----- 669
+ + + MD KY+ V+ +V+ GKQ +K S
Sbjct: 1811 CKDIP--SFVIQMDFSADGKYIQVSTGAYKRQVHEVPLGKQVTEAVVIEKITWASWTSVL 1868
Query: 670 ----------QGDEGSLLKVHVDPSGTFLATSCSDKSISVIDFYSGECIAK---MFGHSE 716
D+ + V +G + T + + DF E AK FGHS
Sbjct: 1869 GDEVIGIWPRNADKADVNCACVTHAGLNIVTGDDFGLVKLFDFPCTEKFAKHKRYFGHSA 1928
Query: 717 IITSMKFTYDCHHLITVSGDSC-VFIW 742
+T+++F+YD ++++ GD C VF+W
Sbjct: 1929 HVTNIRFSYDDKYVVSTGGDDCSVFVW 1955
Score = 32.0 bits (71), Expect = 4.7
Identities = 27/122 (22%), Positives = 53/122 (43%), Gaps = 12/122 (9%)
Query: 112 KSLSALAFSPDGKYIVTGENGHRPAVRIWDVEEKNQVAEMLGHKYGVACVAFSPNM-KHI 170
K ++ + FS GK +V+ + +W +E +VA GH + V F P+
Sbjct: 1463 KGVNYINFSATGKLLVSVGVDPEHTITVWRWQEGAKVASRGGHLERIFVVEFRPDSDTQF 1522
Query: 171 VSMGYQHDMVLNVWD-------WKKDIVVASNKVSCR-VIALSFSEDSSYFVTVGNRHVR 222
VS+G +H + W +KK ++ + + +++++F ++ F N V
Sbjct: 1523 VSVGVKH---MKFWTLAGSALLYKKGVIGSLGAAKMQTMLSVAFGANNLTFTGAINGDVY 1579
Query: 223 FW 224
W
Sbjct: 1580 VW 1581
>gi|56790932 echinoderm microtubule associated protein like 1
isoform a [Homo sapiens]
Length = 834
Score = 70.5 bits (171), Expect = 1e-11
Identities = 62/198 (31%), Positives = 93/198 (46%), Gaps = 17/198 (8%)
Query: 51 ASEETVQNRVSLEKVLGITAQNSSGLTCDPGTGHVAYLAGCVVVILDPKENKQQHIFNTA 110
A E R+ LE V G ++ TG Y VVV+ + +E Q+H +
Sbjct: 231 AKVELPTKRLKLEWVYGYRGRDCRNNLYLLPTGETVYFIASVVVLYNVEEQLQRH-YAGH 289
Query: 111 RKSLSALAFSPDGKYIVTGE------NGHR--PAVRIWDVEEKNQVAEMLGHKY---GVA 159
+ LA PD I TG+ +G + P VRIWD N + ++G + V
Sbjct: 290 NDDVKCLAVHPDRITIATGQVAGTSKDGKQLPPHVRIWDSVTLNTL-HVIGIGFFDRAVT 348
Query: 160 CVAFSPNM--KHIVSMGYQHDMVLNVWDWKKDIVVASNKVSCR-VIALSF-SEDSSYFVT 215
C+AFS + ++ ++ +D VL+VWDW+K+ +A K S V A F D++ VT
Sbjct: 349 CIAFSKSNGGTNLCAVDDSNDHVLSVWDWQKEEKLADVKCSNEAVFAADFHPTDTNIIVT 408
Query: 216 VGNRHVRFWFLEVSTETK 233
G H+ FW LE S+ K
Sbjct: 409 CGKSHLYFWTLEGSSLNK 426
Score = 32.0 bits (71), Expect = 4.7
Identities = 21/78 (26%), Positives = 33/78 (42%), Gaps = 5/78 (6%)
Query: 669 SQGDEGSLLKVHVDPSGTFLATSCSDKSISVIDFYSG----ECIAKMFGHSEIITSMKFT 724
+ G+E L + P G FLA D I + + K GHS IT + ++
Sbjct: 642 TDGNE-QLSVMRYSPDGNFLAIGSHDNCIYIYGVSDNGRKYTRVGKCSGHSSFITHLDWS 700
Query: 725 YDCHHLITVSGDSCVFIW 742
+ L++ SGD + W
Sbjct: 701 VNSQFLVSNSGDYEILYW 718
Score = 31.6 bits (70), Expect = 6.1
Identities = 33/142 (23%), Positives = 60/142 (42%), Gaps = 8/142 (5%)
Query: 54 ETVQNRVSLEKVLGITAQNSSGLTCDPGTGHVAYLAGCVVVILDPKENKQQHIFNTARKS 113
+ V +R +K++ AQ SSG V L G V D + + +
Sbjct: 590 DAVGHRPVWDKIIEDPAQ-SSGFHPSGSVVAVGTLTGRWFVF-DTETKDLVTVHTDGNEQ 647
Query: 114 LSALAFSPDGKYIVTGENGHRPAVRIWDVEEK----NQVAEMLGHKYGVACVAFSPNMKH 169
LS + +SPDG ++ G H + I+ V + +V + GH + + +S N +
Sbjct: 648 LSVMRYSPDGNFLAIG--SHDNCIYIYGVSDNGRKYTRVGKCSGHSSFITHLDWSVNSQF 705
Query: 170 IVSMGYQHDMVLNVWDWKKDIV 191
+VS ++++ V K +V
Sbjct: 706 LVSNSGDYEILYWVPSACKQVV 727
>gi|56790930 echinoderm microtubule associated protein like 1
isoform b [Homo sapiens]
Length = 815
Score = 70.5 bits (171), Expect = 1e-11
Identities = 62/198 (31%), Positives = 93/198 (46%), Gaps = 17/198 (8%)
Query: 51 ASEETVQNRVSLEKVLGITAQNSSGLTCDPGTGHVAYLAGCVVVILDPKENKQQHIFNTA 110
A E R+ LE V G ++ TG Y VVV+ + +E Q+H +
Sbjct: 212 AKVELPTKRLKLEWVYGYRGRDCRNNLYLLPTGETVYFIASVVVLYNVEEQLQRH-YAGH 270
Query: 111 RKSLSALAFSPDGKYIVTGE------NGHR--PAVRIWDVEEKNQVAEMLGHKY---GVA 159
+ LA PD I TG+ +G + P VRIWD N + ++G + V
Sbjct: 271 NDDVKCLAVHPDRITIATGQVAGTSKDGKQLPPHVRIWDSVTLNTL-HVIGIGFFDRAVT 329
Query: 160 CVAFSPNM--KHIVSMGYQHDMVLNVWDWKKDIVVASNKVSCR-VIALSF-SEDSSYFVT 215
C+AFS + ++ ++ +D VL+VWDW+K+ +A K S V A F D++ VT
Sbjct: 330 CIAFSKSNGGTNLCAVDDSNDHVLSVWDWQKEEKLADVKCSNEAVFAADFHPTDTNIIVT 389
Query: 216 VGNRHVRFWFLEVSTETK 233
G H+ FW LE S+ K
Sbjct: 390 CGKSHLYFWTLEGSSLNK 407
Score = 32.0 bits (71), Expect = 4.7
Identities = 21/78 (26%), Positives = 33/78 (42%), Gaps = 5/78 (6%)
Query: 669 SQGDEGSLLKVHVDPSGTFLATSCSDKSISVIDFYSG----ECIAKMFGHSEIITSMKFT 724
+ G+E L + P G FLA D I + + K GHS IT + ++
Sbjct: 623 TDGNE-QLSVMRYSPDGNFLAIGSHDNCIYIYGVSDNGRKYTRVGKCSGHSSFITHLDWS 681
Query: 725 YDCHHLITVSGDSCVFIW 742
+ L++ SGD + W
Sbjct: 682 VNSQFLVSNSGDYEILYW 699
Score = 31.6 bits (70), Expect = 6.1
Identities = 33/142 (23%), Positives = 60/142 (42%), Gaps = 8/142 (5%)
Query: 54 ETVQNRVSLEKVLGITAQNSSGLTCDPGTGHVAYLAGCVVVILDPKENKQQHIFNTARKS 113
+ V +R +K++ AQ SSG V L G V D + + +
Sbjct: 571 DAVGHRPVWDKIIEDPAQ-SSGFHPSGSVVAVGTLTGRWFVF-DTETKDLVTVHTDGNEQ 628
Query: 114 LSALAFSPDGKYIVTGENGHRPAVRIWDVEEK----NQVAEMLGHKYGVACVAFSPNMKH 169
LS + +SPDG ++ G H + I+ V + +V + GH + + +S N +
Sbjct: 629 LSVMRYSPDGNFLAIG--SHDNCIYIYGVSDNGRKYTRVGKCSGHSSFITHLDWSVNSQF 686
Query: 170 IVSMGYQHDMVLNVWDWKKDIV 191
+VS ++++ V K +V
Sbjct: 687 LVSNSGDYEILYWVPSACKQVV 708
>gi|48928050 F-box and WD repeat domain containing 11 isoform C
[Homo sapiens]
Length = 542
Score = 66.2 bits (160), Expect = 2e-10
Identities = 58/259 (22%), Positives = 111/259 (42%), Gaps = 29/259 (11%)
Query: 503 DGQHLASGDRSGNLRIHELHFMDELVKVEAHDAEVLCLEYSKPETGLTLLASASRDRLIH 562
D + + SG R +++I + ++ L + H VLCL+Y + ++ + S D +
Sbjct: 249 DDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQYDE-----RVIVTGSSDSTVR 303
Query: 563 VLNVEKNYNLEQTLDDHSSSITAIKFAGNRDIQMISCGADKSIYFRSAQQGSD-GLHFVR 621
V +V L TL H+ ++ ++F+ M++C D+SI +D L V
Sbjct: 304 VWDVNTGEVL-NTLIHHNEAVLHLRFSNG---LMVTCSKDRSIAVWDMASATDITLRRVL 359
Query: 622 THHVAEKTTLYDMDIDITQKYVAVACQDRNVRVYNTVNGKQKKCYKGSQGDEGSLLKVHV 681
H A +D KY+ A DR ++V++T + + G + L
Sbjct: 360 VGHRAAVNV-----VDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACL----- 409
Query: 682 DPSGTFLATSCSDKSISVIDFYSGECIAKMFGHSEIITSMKFTYDCHHLITVSGDSCVFI 741
+ + SD +I + D G C+ + GH E++ ++F D +++ + D + +
Sbjct: 410 QYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRF--DNKRIVSGAYDGKIKV 467
Query: 742 WHL-------GPEITNCMK 753
W L P T C++
Sbjct: 468 WDLQAALDPRAPASTLCLR 486
Score = 35.8 bits (81), Expect = 0.32
Identities = 31/113 (27%), Positives = 45/113 (39%), Gaps = 9/113 (7%)
Query: 115 SALAFSPDGKYIVTGENGHRPAVRIWDVEEKNQVAEMLGHKYGVACVAFSPNMKHIVSMG 174
S L D + IVTG + VR+WDV + ++ H V + FS + S
Sbjct: 282 SVLCLQYDERVIVTGSSDS--TVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCS-- 337
Query: 175 YQHDMVLNVWDWKK--DIVVASNKVSCRVIALSFSEDSSYFVTV-GNRHVRFW 224
D + VWD DI + V R D Y V+ G+R ++ W
Sbjct: 338 --KDRSIAVWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVW 388
Score = 33.5 bits (75), Expect = 1.6
Identities = 50/222 (22%), Positives = 94/222 (42%), Gaps = 32/222 (14%)
Query: 379 KDHSIYIWDVKDINRVGKVWSELFHSSYVWNVEVYPEFEDQRACLPSGSFLTCSSDNTIR 438
+D+SI IWD + + + H+ V ++ D+R +T SSD+T+R
Sbjct: 258 RDNSIKIWDKTSLECLKVLTG---HTGSVLCLQY-----DERV------IVTGSSDSTVR 303
Query: 439 FWNLDS----SPDSHWQKNI----FSNTLLKVVYVENDIQHLQDMSHFPDRGSENGTPMD 490
W++++ + H + + FSN L+ + I + DM+ D + +
Sbjct: 304 VWDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKDRSIA-VWDMASATDI-TLRRVLVG 361
Query: 491 VKAGVRVMQVSPDGQHLASGDRSGNLRIHELHFMDELVKVEAHDAEVLCLEYSKPETGLT 550
+A V V+ ASGDR+ +++ + + + H + CL+Y
Sbjct: 362 HRAAVNVVDFDDKYIVSASGDRT--IKVWSTSTCEFVRTLNGHKRGIACLQYRD-----R 414
Query: 551 LLASASRDRLIHVLNVEKNYNLEQTLDDHSSSITAIKFAGNR 592
L+ S S D I + ++E L + L+ H + I+F R
Sbjct: 415 LVVSGSSDNTIRLWDIECGACL-RVLEGHEELVRCIRFDNKR 455
Score = 32.7 bits (73), Expect = 2.7
Identities = 20/64 (31%), Positives = 33/64 (51%), Gaps = 6/64 (9%)
Query: 122 DGKYIVTGENGHRPAVRIWDVEEKNQVAEMLGHKYGVACVAFSPNMKHIVSMGYQHDMVL 181
D KYIV+ +G R +++W V + GHK G+AC+ + + +VS D +
Sbjct: 372 DDKYIVSA-SGDR-TIKVWSTSTCEFVRTLNGHKRGIACLQYRDRL--VVS--GSSDNTI 425
Query: 182 NVWD 185
+WD
Sbjct: 426 RLWD 429
Score = 32.0 bits (71), Expect = 4.7
Identities = 20/62 (32%), Positives = 34/62 (54%), Gaps = 6/62 (9%)
Query: 124 KYIVTGENGHRPAVRIWDVEEKNQVAEMLGHKYGVACVAFSPNMKHIVSMGYQHDMVLNV 183
+ +V+G + + +R+WD+E + + GH+ V C+ F + K IVS Y D + V
Sbjct: 414 RLVVSGSSDN--TIRLWDIECGACLRVLEGHEELVRCIRF--DNKRIVSGAY--DGKIKV 467
Query: 184 WD 185
WD
Sbjct: 468 WD 469
>gi|48928048 F-box and WD repeat domain containing 11 isoform A
[Homo sapiens]
Length = 508
Score = 66.2 bits (160), Expect = 2e-10
Identities = 58/259 (22%), Positives = 111/259 (42%), Gaps = 29/259 (11%)
Query: 503 DGQHLASGDRSGNLRIHELHFMDELVKVEAHDAEVLCLEYSKPETGLTLLASASRDRLIH 562
D + + SG R +++I + ++ L + H VLCL+Y + ++ + S D +
Sbjct: 215 DDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQYDE-----RVIVTGSSDSTVR 269
Query: 563 VLNVEKNYNLEQTLDDHSSSITAIKFAGNRDIQMISCGADKSIYFRSAQQGSD-GLHFVR 621
V +V L TL H+ ++ ++F+ M++C D+SI +D L V
Sbjct: 270 VWDVNTGEVL-NTLIHHNEAVLHLRFSNG---LMVTCSKDRSIAVWDMASATDITLRRVL 325
Query: 622 THHVAEKTTLYDMDIDITQKYVAVACQDRNVRVYNTVNGKQKKCYKGSQGDEGSLLKVHV 681
H A +D KY+ A DR ++V++T + + G + L
Sbjct: 326 VGHRAAVNV-----VDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACL----- 375
Query: 682 DPSGTFLATSCSDKSISVIDFYSGECIAKMFGHSEIITSMKFTYDCHHLITVSGDSCVFI 741
+ + SD +I + D G C+ + GH E++ ++F D +++ + D + +
Sbjct: 376 QYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRF--DNKRIVSGAYDGKIKV 433
Query: 742 WHL-------GPEITNCMK 753
W L P T C++
Sbjct: 434 WDLQAALDPRAPASTLCLR 452
Score = 35.8 bits (81), Expect = 0.32
Identities = 31/113 (27%), Positives = 45/113 (39%), Gaps = 9/113 (7%)
Query: 115 SALAFSPDGKYIVTGENGHRPAVRIWDVEEKNQVAEMLGHKYGVACVAFSPNMKHIVSMG 174
S L D + IVTG + VR+WDV + ++ H V + FS + S
Sbjct: 248 SVLCLQYDERVIVTGSSDS--TVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCS-- 303
Query: 175 YQHDMVLNVWDWKK--DIVVASNKVSCRVIALSFSEDSSYFVTV-GNRHVRFW 224
D + VWD DI + V R D Y V+ G+R ++ W
Sbjct: 304 --KDRSIAVWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVW 354
Score = 33.5 bits (75), Expect = 1.6
Identities = 50/222 (22%), Positives = 94/222 (42%), Gaps = 32/222 (14%)
Query: 379 KDHSIYIWDVKDINRVGKVWSELFHSSYVWNVEVYPEFEDQRACLPSGSFLTCSSDNTIR 438
+D+SI IWD + + + H+ V ++ D+R +T SSD+T+R
Sbjct: 224 RDNSIKIWDKTSLECLKVLTG---HTGSVLCLQY-----DERV------IVTGSSDSTVR 269
Query: 439 FWNLDS----SPDSHWQKNI----FSNTLLKVVYVENDIQHLQDMSHFPDRGSENGTPMD 490
W++++ + H + + FSN L+ + I + DM+ D + +
Sbjct: 270 VWDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKDRSIA-VWDMASATDI-TLRRVLVG 327
Query: 491 VKAGVRVMQVSPDGQHLASGDRSGNLRIHELHFMDELVKVEAHDAEVLCLEYSKPETGLT 550
+A V V+ ASGDR+ +++ + + + H + CL+Y
Sbjct: 328 HRAAVNVVDFDDKYIVSASGDRT--IKVWSTSTCEFVRTLNGHKRGIACLQYRD-----R 380
Query: 551 LLASASRDRLIHVLNVEKNYNLEQTLDDHSSSITAIKFAGNR 592
L+ S S D I + ++E L + L+ H + I+F R
Sbjct: 381 LVVSGSSDNTIRLWDIECGACL-RVLEGHEELVRCIRFDNKR 421
Score = 32.7 bits (73), Expect = 2.7
Identities = 20/64 (31%), Positives = 33/64 (51%), Gaps = 6/64 (9%)
Query: 122 DGKYIVTGENGHRPAVRIWDVEEKNQVAEMLGHKYGVACVAFSPNMKHIVSMGYQHDMVL 181
D KYIV+ +G R +++W V + GHK G+AC+ + + +VS D +
Sbjct: 338 DDKYIVSA-SGDR-TIKVWSTSTCEFVRTLNGHKRGIACLQYRDRL--VVS--GSSDNTI 391
Query: 182 NVWD 185
+WD
Sbjct: 392 RLWD 395
Score = 32.0 bits (71), Expect = 4.7
Identities = 20/62 (32%), Positives = 34/62 (54%), Gaps = 6/62 (9%)
Query: 124 KYIVTGENGHRPAVRIWDVEEKNQVAEMLGHKYGVACVAFSPNMKHIVSMGYQHDMVLNV 183
+ +V+G + + +R+WD+E + + GH+ V C+ F + K IVS Y D + V
Sbjct: 380 RLVVSGSSDN--TIRLWDIECGACLRVLEGHEELVRCIRF--DNKRIVSGAY--DGKIKV 433
Query: 184 WD 185
WD
Sbjct: 434 WD 435
>gi|48928046 F-box and WD repeat domain containing 11 isoform B
[Homo sapiens]
Length = 529
Score = 66.2 bits (160), Expect = 2e-10
Identities = 58/259 (22%), Positives = 111/259 (42%), Gaps = 29/259 (11%)
Query: 503 DGQHLASGDRSGNLRIHELHFMDELVKVEAHDAEVLCLEYSKPETGLTLLASASRDRLIH 562
D + + SG R +++I + ++ L + H VLCL+Y + ++ + S D +
Sbjct: 236 DDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQYDE-----RVIVTGSSDSTVR 290
Query: 563 VLNVEKNYNLEQTLDDHSSSITAIKFAGNRDIQMISCGADKSIYFRSAQQGSD-GLHFVR 621
V +V L TL H+ ++ ++F+ M++C D+SI +D L V
Sbjct: 291 VWDVNTGEVL-NTLIHHNEAVLHLRFSNG---LMVTCSKDRSIAVWDMASATDITLRRVL 346
Query: 622 THHVAEKTTLYDMDIDITQKYVAVACQDRNVRVYNTVNGKQKKCYKGSQGDEGSLLKVHV 681
H A +D KY+ A DR ++V++T + + G + L
Sbjct: 347 VGHRAAVNV-----VDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACL----- 396
Query: 682 DPSGTFLATSCSDKSISVIDFYSGECIAKMFGHSEIITSMKFTYDCHHLITVSGDSCVFI 741
+ + SD +I + D G C+ + GH E++ ++F D +++ + D + +
Sbjct: 397 QYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRF--DNKRIVSGAYDGKIKV 454
Query: 742 WHL-------GPEITNCMK 753
W L P T C++
Sbjct: 455 WDLQAALDPRAPASTLCLR 473
Score = 35.8 bits (81), Expect = 0.32
Identities = 31/113 (27%), Positives = 45/113 (39%), Gaps = 9/113 (7%)
Query: 115 SALAFSPDGKYIVTGENGHRPAVRIWDVEEKNQVAEMLGHKYGVACVAFSPNMKHIVSMG 174
S L D + IVTG + VR+WDV + ++ H V + FS + S
Sbjct: 269 SVLCLQYDERVIVTGSSDS--TVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCS-- 324
Query: 175 YQHDMVLNVWDWKK--DIVVASNKVSCRVIALSFSEDSSYFVTV-GNRHVRFW 224
D + VWD DI + V R D Y V+ G+R ++ W
Sbjct: 325 --KDRSIAVWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVW 375
Score = 33.5 bits (75), Expect = 1.6
Identities = 50/222 (22%), Positives = 94/222 (42%), Gaps = 32/222 (14%)
Query: 379 KDHSIYIWDVKDINRVGKVWSELFHSSYVWNVEVYPEFEDQRACLPSGSFLTCSSDNTIR 438
+D+SI IWD + + + H+ V ++ D+R +T SSD+T+R
Sbjct: 245 RDNSIKIWDKTSLECLKVLTG---HTGSVLCLQY-----DERV------IVTGSSDSTVR 290
Query: 439 FWNLDS----SPDSHWQKNI----FSNTLLKVVYVENDIQHLQDMSHFPDRGSENGTPMD 490
W++++ + H + + FSN L+ + I + DM+ D + +
Sbjct: 291 VWDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKDRSIA-VWDMASATDI-TLRRVLVG 348
Query: 491 VKAGVRVMQVSPDGQHLASGDRSGNLRIHELHFMDELVKVEAHDAEVLCLEYSKPETGLT 550
+A V V+ ASGDR+ +++ + + + H + CL+Y
Sbjct: 349 HRAAVNVVDFDDKYIVSASGDRT--IKVWSTSTCEFVRTLNGHKRGIACLQYRD-----R 401
Query: 551 LLASASRDRLIHVLNVEKNYNLEQTLDDHSSSITAIKFAGNR 592
L+ S S D I + ++E L + L+ H + I+F R
Sbjct: 402 LVVSGSSDNTIRLWDIECGACL-RVLEGHEELVRCIRFDNKR 442
Score = 32.7 bits (73), Expect = 2.7
Identities = 20/64 (31%), Positives = 33/64 (51%), Gaps = 6/64 (9%)
Query: 122 DGKYIVTGENGHRPAVRIWDVEEKNQVAEMLGHKYGVACVAFSPNMKHIVSMGYQHDMVL 181
D KYIV+ +G R +++W V + GHK G+AC+ + + +VS D +
Sbjct: 359 DDKYIVSA-SGDR-TIKVWSTSTCEFVRTLNGHKRGIACLQYRDRL--VVS--GSSDNTI 412
Query: 182 NVWD 185
+WD
Sbjct: 413 RLWD 416
Score = 32.0 bits (71), Expect = 4.7
Identities = 20/62 (32%), Positives = 34/62 (54%), Gaps = 6/62 (9%)
Query: 124 KYIVTGENGHRPAVRIWDVEEKNQVAEMLGHKYGVACVAFSPNMKHIVSMGYQHDMVLNV 183
+ +V+G + + +R+WD+E + + GH+ V C+ F + K IVS Y D + V
Sbjct: 401 RLVVSGSSDN--TIRLWDIECGACLRVLEGHEELVRCIRF--DNKRIVSGAY--DGKIKV 454
Query: 184 WD 185
WD
Sbjct: 455 WD 456
>gi|26665869 WD repeat domain 51B [Homo sapiens]
Length = 478
Score = 66.2 bits (160), Expect = 2e-10
Identities = 69/295 (23%), Positives = 128/295 (43%), Gaps = 28/295 (9%)
Query: 495 VRVMQVSPDGQHLASGDRSGNLRIHELHFMDELVKVEAHDAEVLCLEYSKPETGLTLLAS 554
V +Q SP G LAS R +R+ + + +AH A V +++S LA+
Sbjct: 63 VTSVQFSPHGNLLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQ---FLAT 119
Query: 555 ASRDRLIHVLNVEKNYNLEQTLDDHSSSITAIKFAGNRDIQMISCGADKSIYF------R 608
AS D+ I V ++ + L +L H+ + KF+ + + ++SC DK+I +
Sbjct: 120 ASEDKSIKVWSMYRQRFL-YSLYRHTHWVRCAKFSPDGRL-IVSCSEDKTIKIWDTTNKQ 177
Query: 609 SAQQGSDGLHFVRTHHVAEKTTLYDMDIDITQKYVAVACQDRNVRVYNTVNGKQKKCYKG 668
SD + F +D + + +A A D+ V+V++ K + Y
Sbjct: 178 CVNNFSDSVGFANF-----------VDFNPSGTCIASAGSDQTVKVWDVRVNKLLQHY-- 224
Query: 669 SQGDEGSLLKVHVDPSGTFLATSCSDKSISVIDFYSGECIAKMFGHSEIITSMKFTYDCH 728
Q G + + PSG +L T+ SD ++ ++D G I + GH+ + ++ F+
Sbjct: 225 -QVHSGGVNCISFHPSGNYLITASSDGTLKILDLLEGRLIYTLQGHTGPVFTVSFSKGGE 283
Query: 729 HLITVSGDSCVFIWHLGPEITNC--MKQHLLEIDHRQQQQHTND-KKRSGHPRQD 780
+ D+ V +W + +C + + L+ H H D R+ HP ++
Sbjct: 284 LFASGGADTQVLLWRTNFDELHCKGLTKRNLKRLHFDSPPHLLDIYPRTPHPHEE 338
Score = 46.6 bits (109), Expect = 2e-04
Identities = 39/171 (22%), Positives = 73/171 (42%), Gaps = 9/171 (5%)
Query: 572 LEQTLDDHSSSITAIKFAGNRDIQMISCGADKSIYFRSAQQGSDGLHFVRTHHVAEKTTL 631
LE+ H ++IT++ + N Q+ + D + + + H +V K +
Sbjct: 10 LERYFKGHKAAITSLDLSPNGK-QLATASWDTFLMLWNFKP-----HARAYRYVGHKDVV 63
Query: 632 YDMDIDITQKYVAVACQDRNVRVYNTVNGKQKKCYKGSQGDEGSLLKVHVDPSGTFLATS 691
+ +A A +DR VR++ + K+ K + + + V G FLAT+
Sbjct: 64 TSVQFSPHGNLLASASRDRTVRLW--IPDKRGK-FSEFKAHTAPVRSVDFSADGQFLATA 120
Query: 692 CSDKSISVIDFYSGECIAKMFGHSEIITSMKFTYDCHHLITVSGDSCVFIW 742
DKSI V Y + ++ H+ + KF+ D +++ S D + IW
Sbjct: 121 SEDKSIKVWSMYRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIW 171
Score = 39.3 bits (90), Expect = 0.029
Identities = 19/79 (24%), Positives = 38/79 (48%), Gaps = 4/79 (5%)
Query: 107 FNTARKSLSALAFSPDGKYIVTGENGHRPAVRIWDVEEKNQVAEMLGHKYGVACVAFSPN 166
F + ++ FS DG+++ T ++++W + + + + H + V C FSP+
Sbjct: 98 FKAHTAPVRSVDFSADGQFLATASEDK--SIKVWSMYRQRFLYSLYRHTHWVRCAKFSPD 155
Query: 167 MKHIVSMGYQHDMVLNVWD 185
+ IVS D + +WD
Sbjct: 156 GRLIVSC--SEDKTIKIWD 172
Score = 35.4 bits (80), Expect = 0.42
Identities = 26/108 (24%), Positives = 47/108 (43%), Gaps = 6/108 (5%)
Query: 119 FSPDGKYIVTGENGHRPAVRIWDVEEKNQVAEMLGHKYGVACVAFSPNMKHIVSMGYQHD 178
F+P G I + G V++WDV + H GV C++F P+ ++++ D
Sbjct: 194 FNPSGTCIASA--GSDQTVKVWDVRVNKLLQHYQVHSGGVNCISFHPSGNYLITA--SSD 249
Query: 179 MVLNVWDWKKD-IVVASNKVSCRVIALSFSEDSSYFVTVG-NRHVRFW 224
L + D + ++ + V +SFS+ F + G + V W
Sbjct: 250 GTLKILDLLEGRLIYTLQGHTGPVFTVSFSKGGELFASGGADTQVLLW 297
Score = 35.0 bits (79), Expect = 0.55
Identities = 27/123 (21%), Positives = 54/123 (43%), Gaps = 6/123 (4%)
Query: 104 QHIFNTARKSLSALAFSPDGKYIVTGENGHRPAVRIWDVEEKNQVAEMLGHKYGVACVAF 163
+ F + ++++L SP+GK + T + +W+ + + +GHK V V F
Sbjct: 11 ERYFKGHKAAITSLDLSPNGKQLATAS--WDTFLMLWNFKPHARAYRYVGHKDVVTSVQF 68
Query: 164 SPNMKHIVSMGYQHDMVLNVWDWKKDIVVASNKV-SCRVIALSFSEDSSYFVTVG-NRHV 221
SP+ + S D + +W K + K + V ++ FS D + T ++ +
Sbjct: 69 SPHGNLLASA--SRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSI 126
Query: 222 RFW 224
+ W
Sbjct: 127 KVW 129
Score = 34.7 bits (78), Expect = 0.72
Identities = 41/185 (22%), Positives = 70/185 (37%), Gaps = 42/185 (22%)
Query: 396 KVWSELFHSSYVWNVEVYPEFEDQRACLPSGSFL-TCSSDNTIRFWN------------- 441
KVWS ++ +++++ + + P G + +CS D TI+ W+
Sbjct: 127 KVWS-MYRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDS 185
Query: 442 ------LDSSPDSHWQKNIFSNTLLKV--VYVENDIQHLQDMSHFPDRGSENGTPMDVKA 493
+D +P + S+ +KV V V +QH Q S
Sbjct: 186 VGFANFVDFNPSGTCIASAGSDQTVKVWDVRVNKLLQHYQVHS----------------G 229
Query: 494 GVRVMQVSPDGQHLASGDRSGNLRIHELHFMDELVKVEAHDAEVLCLEYSKPETGLTLLA 553
GV + P G +L + G L+I +L + ++ H V + +SK G L A
Sbjct: 230 GVNCISFHPSGNYLITASSDGTLKILDLLEGRLIYTLQGHTGPVFTVSFSK---GGELFA 286
Query: 554 SASRD 558
S D
Sbjct: 287 SGGAD 291
Score = 32.0 bits (71), Expect = 4.7
Identities = 21/89 (23%), Positives = 40/89 (44%), Gaps = 2/89 (2%)
Query: 93 VVILDPKENKQQHIFNTARKSLSALAFSPDGKYIVTGENGHRPAVRIWDVEEKNQVAEML 152
V + D + NK + ++ ++F P G Y++T + ++I D+ E + +
Sbjct: 210 VKVWDVRVNKLLQHYQVHSGGVNCISFHPSGNYLITASSD--GTLKILDLLEGRLIYTLQ 267
Query: 153 GHKYGVACVAFSPNMKHIVSMGYQHDMVL 181
GH V V+FS + S G ++L
Sbjct: 268 GHTGPVFTVSFSKGGELFASGGADTQVLL 296
>gi|4502477 beta-transducin repeat containing protein isoform 2
[Homo sapiens]
Length = 569
Score = 65.5 bits (158), Expect = 4e-10
Identities = 59/256 (23%), Positives = 108/256 (42%), Gaps = 24/256 (9%)
Query: 490 DVKAGVRVMQVSPDGQHLASGDRSGNLRIHELHFMDELVKVEAHDAEVLCLEYSKPETGL 549
+ GV +Q D Q + SG R ++I + + ++ + H VLCL+Y +
Sbjct: 265 ETSKGVYCLQY--DDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDE----- 317
Query: 550 TLLASASRDRLIHVLNVEKNYNLEQTLDDHSSSITAIKFAGNRDIQMISCGADKSIYFRS 609
++ + S D + V +V L TL H ++ ++F M++C D+SI
Sbjct: 318 RVIITGSSDSTVRVWDVNTGEMLN-TLIHHCEAVLHLRFNNG---MMVTCSKDRSIAVWD 373
Query: 610 AQQGSD-GLHFVRTHHVAEKTTLYDMDIDITQKYVAVACQDRNVRVYNTVNGKQKKCYKG 668
+D L V H A +D KY+ A DR ++V+NT + + G
Sbjct: 374 MASPTDITLRRVLVGHRAAVNV-----VDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNG 428
Query: 669 SQGDEGSLLKVHVDPSGTFLATSCSDKSISVIDFYSGECIAKMFGHSEIITSMKFTYDCH 728
+ L + + SD +I + D G C+ + GH E++ ++F D
Sbjct: 429 HKRGIACL-----QYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRF--DNK 481
Query: 729 HLITVSGDSCVFIWHL 744
+++ + D + +W L
Sbjct: 482 RIVSGAYDGKIKVWDL 497
Score = 35.0 bits (79), Expect = 0.55
Identities = 30/113 (26%), Positives = 45/113 (39%), Gaps = 9/113 (7%)
Query: 115 SALAFSPDGKYIVTGENGHRPAVRIWDVEEKNQVAEMLGHKYGVACVAFSPNMKHIVSMG 174
S L D + I+TG + VR+WDV + ++ H V + F+ M S
Sbjct: 309 SVLCLQYDERVIITGSSDS--TVRVWDVNTGEMLNTLIHHCEAVLHLRFNNGMMVTCS-- 364
Query: 175 YQHDMVLNVWDWKK--DIVVASNKVSCRVIALSFSEDSSYFVTV-GNRHVRFW 224
D + VWD DI + V R D Y V+ G+R ++ W
Sbjct: 365 --KDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVW 415
Score = 33.1 bits (74), Expect = 2.1
Identities = 20/64 (31%), Positives = 34/64 (53%), Gaps = 6/64 (9%)
Query: 122 DGKYIVTGENGHRPAVRIWDVEEKNQVAEMLGHKYGVACVAFSPNMKHIVSMGYQHDMVL 181
D KYIV+ +G R +++W+ V + GHK G+AC+ + + +VS D +
Sbjct: 399 DDKYIVSA-SGDR-TIKVWNTSTCEFVRTLNGHKRGIACLQYRDRL--VVS--GSSDNTI 452
Query: 182 NVWD 185
+WD
Sbjct: 453 RLWD 456
Score = 32.0 bits (71), Expect = 4.7
Identities = 20/62 (32%), Positives = 34/62 (54%), Gaps = 6/62 (9%)
Query: 124 KYIVTGENGHRPAVRIWDVEEKNQVAEMLGHKYGVACVAFSPNMKHIVSMGYQHDMVLNV 183
+ +V+G + + +R+WD+E + + GH+ V C+ F + K IVS Y D + V
Sbjct: 441 RLVVSGSSDN--TIRLWDIECGACLRVLEGHEELVRCIRF--DNKRIVSGAY--DGKIKV 494
Query: 184 WD 185
WD
Sbjct: 495 WD 496
>gi|16117783 beta-transducin repeat containing protein isoform 1
[Homo sapiens]
Length = 605
Score = 65.5 bits (158), Expect = 4e-10
Identities = 59/256 (23%), Positives = 108/256 (42%), Gaps = 24/256 (9%)
Query: 490 DVKAGVRVMQVSPDGQHLASGDRSGNLRIHELHFMDELVKVEAHDAEVLCLEYSKPETGL 549
+ GV +Q D Q + SG R ++I + + ++ + H VLCL+Y +
Sbjct: 301 ETSKGVYCLQY--DDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDE----- 353
Query: 550 TLLASASRDRLIHVLNVEKNYNLEQTLDDHSSSITAIKFAGNRDIQMISCGADKSIYFRS 609
++ + S D + V +V L TL H ++ ++F M++C D+SI
Sbjct: 354 RVIITGSSDSTVRVWDVNTGEMLN-TLIHHCEAVLHLRFNNG---MMVTCSKDRSIAVWD 409
Query: 610 AQQGSD-GLHFVRTHHVAEKTTLYDMDIDITQKYVAVACQDRNVRVYNTVNGKQKKCYKG 668
+D L V H A +D KY+ A DR ++V+NT + + G
Sbjct: 410 MASPTDITLRRVLVGHRAAVNV-----VDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNG 464
Query: 669 SQGDEGSLLKVHVDPSGTFLATSCSDKSISVIDFYSGECIAKMFGHSEIITSMKFTYDCH 728
+ L + + SD +I + D G C+ + GH E++ ++F D
Sbjct: 465 HKRGIACL-----QYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRF--DNK 517
Query: 729 HLITVSGDSCVFIWHL 744
+++ + D + +W L
Sbjct: 518 RIVSGAYDGKIKVWDL 533
Score = 35.0 bits (79), Expect = 0.55
Identities = 30/113 (26%), Positives = 45/113 (39%), Gaps = 9/113 (7%)
Query: 115 SALAFSPDGKYIVTGENGHRPAVRIWDVEEKNQVAEMLGHKYGVACVAFSPNMKHIVSMG 174
S L D + I+TG + VR+WDV + ++ H V + F+ M S
Sbjct: 345 SVLCLQYDERVIITGSSDS--TVRVWDVNTGEMLNTLIHHCEAVLHLRFNNGMMVTCS-- 400
Query: 175 YQHDMVLNVWDWKK--DIVVASNKVSCRVIALSFSEDSSYFVTV-GNRHVRFW 224
D + VWD DI + V R D Y V+ G+R ++ W
Sbjct: 401 --KDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVW 451
Score = 33.1 bits (74), Expect = 2.1
Identities = 20/64 (31%), Positives = 34/64 (53%), Gaps = 6/64 (9%)
Query: 122 DGKYIVTGENGHRPAVRIWDVEEKNQVAEMLGHKYGVACVAFSPNMKHIVSMGYQHDMVL 181
D KYIV+ +G R +++W+ V + GHK G+AC+ + + +VS D +
Sbjct: 435 DDKYIVSA-SGDR-TIKVWNTSTCEFVRTLNGHKRGIACLQYRDRL--VVS--GSSDNTI 488
Query: 182 NVWD 185
+WD
Sbjct: 489 RLWD 492
Score = 32.0 bits (71), Expect = 4.7
Identities = 20/62 (32%), Positives = 34/62 (54%), Gaps = 6/62 (9%)
Query: 124 KYIVTGENGHRPAVRIWDVEEKNQVAEMLGHKYGVACVAFSPNMKHIVSMGYQHDMVLNV 183
+ +V+G + + +R+WD+E + + GH+ V C+ F + K IVS Y D + V
Sbjct: 477 RLVVSGSSDN--TIRLWDIECGACLRVLEGHEELVRCIRF--DNKRIVSGAY--DGKIKV 530
Query: 184 WD 185
WD
Sbjct: 531 WD 532
>gi|6912356 echinoderm microtubule associated protein like 2 [Homo
sapiens]
Length = 649
Score = 65.1 bits (157), Expect = 5e-10
Identities = 58/212 (27%), Positives = 88/212 (41%), Gaps = 24/212 (11%)
Query: 37 APPICLRRRTRLSTASEETVQNRVSLEKVLGITAQNSSGLTCDPGTGHVAYLAGCVVVIL 96
AP L R+ L + R+ LE V G ++ TG + Y V V+
Sbjct: 39 APTYSLDTRSELPSC-------RLKLEWVYGYRGRDCRANLYLLPTGEIVYFVASVAVLY 91
Query: 97 DPKENKQQHIFNTARKSLSALAFSPDGKYIVTGENGHR--------PAVRIWDVEEKNQV 148
+E +Q+H + LA PD I TG+ P VRIWD + +
Sbjct: 92 SVEEQRQRHYLGH-NDDIKCLAIHPDMVTIATGQVAGTTKEGKPLPPHVRIWDSVSLSTL 150
Query: 149 AEMLG---HKYGVACVAFSPNM--KHIVSMGYQHDMVLNVWDWKKDIVVASNKVS--CRV 201
+LG V CV FS + + ++ +D +L+VWDW K+ V K S +
Sbjct: 151 -HVLGLGVFDRAVCCVGFSKSNGGNLLCAVDESNDHMLSVWDWAKETKVVDVKCSNEAVL 209
Query: 202 IALSFSEDSSYFVTVGNRHVRFWFLEVSTETK 233
+A D + +T G H+ FW LE + +K
Sbjct: 210 VATFHPTDPTVLITCGKSHIYFWTLEGGSLSK 241
Score = 33.5 bits (75), Expect = 1.6
Identities = 20/68 (29%), Positives = 27/68 (39%), Gaps = 4/68 (5%)
Query: 679 VHVDPSGTFLATSCSDKSISVIDFYSG----ECIAKMFGHSEIITSMKFTYDCHHLITVS 734
V P G +LA D + V G + K GHS IT + + D +T S
Sbjct: 466 VSFSPDGAYLAVGSHDNLVYVYTVDQGGRKVSRLGKCSGHSSFITHLDWAQDSSCFVTNS 525
Query: 735 GDSCVFIW 742
GD + W
Sbjct: 526 GDYEILYW 533
Score = 31.6 bits (70), Expect = 6.1
Identities = 16/60 (26%), Positives = 30/60 (50%), Gaps = 2/60 (3%)
Query: 94 VILDPKENKQQHIFNTARKSLSALAFSPDGKYIVTGENGHRPAVRIWDVEEKNQVAEMLG 153
++LD + + I + +S ++FSPDG Y+ G H V ++ V++ + LG
Sbjct: 443 LLLDTETHDLVAIHTDGNEQISVVSFSPDGAYLAVG--SHDNLVYVYTVDQGGRKVSRLG 500
>gi|16554629 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 63.5 bits (153), Expect = 1e-09
Identities = 50/210 (23%), Positives = 98/210 (46%), Gaps = 17/210 (8%)
Query: 538 LCLEYSKPETGL-----TLLASASRDRLIHVLNVEKNYNLEQTLDDHSSSITAIKFAGNR 592
+ E KPET T +SA++ + V+ NY L+ TL H+ +++++KF+ N
Sbjct: 1 MATEEKKPETEAARAQPTPSSSATQSK---PTPVKPNYALKFTLAGHTKAVSSVKFSPNG 57
Query: 593 DIQMISCGADKSIYFRSAQQGSDGLHFVRTHHVAEKTTLYDMDIDITQKYVAVACQDRNV 652
+ + S ADK I A G F +T K + D+ + A D+ +
Sbjct: 58 E-WLASSSADKLIKIWGAYDGK----FEKTIS-GHKLGISDVAWSSDSNLLVSASDDKTL 111
Query: 653 RVYNTVNGKQKKCYKGSQGDEGSLLKVHVDPSGTFLATSCSDKSISVIDFYSGECIAKMF 712
++++ +GK C K +G + + +P + + D+S+ + D +G+C+ +
Sbjct: 112 KIWDVSSGK---CLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLP 168
Query: 713 GHSEIITSMKFTYDCHHLITVSGDSCVFIW 742
HS+ ++++ F D +++ S D IW
Sbjct: 169 AHSDPVSAVHFNRDGSLIVSSSYDGLCRIW 198
Score = 50.8 bits (120), Expect = 1e-05
Identities = 49/230 (21%), Positives = 98/230 (42%), Gaps = 11/230 (4%)
Query: 492 KAGVRVMQVSPDGQHLASGDRSGNLRIHELHFMDELVKVEAHDAEVLCLEYSKPETGLTL 551
K G+ + S D L S L+I ++ L ++ H V C ++ P++ L
Sbjct: 87 KLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFN-PQSNL-- 143
Query: 552 LASASRDRLIHVLNVEKNYNLEQTLDDHSSSITAIKFAGNRDIQMI-SCGADKSIYFRSA 610
+ S S D + + +V+ L+ TL HS ++A+ F NRD +I S D
Sbjct: 144 IVSGSFDESVRIWDVKTGKCLK-TLPAHSDPVSAVHF--NRDGSLIVSSSYDGLCRIWDT 200
Query: 611 QQGSDGLHFVRTHHVAEKTTLYDMDIDITQKYVAVACQDRNVRVYNTVNGKQKKCYKGSQ 670
G ++T + + + KY+ A D +++++ GK K Y G +
Sbjct: 201 ASGQ----CLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHK 256
Query: 671 GDEGSLLKVHVDPSGTFLATSCSDKSISVIDFYSGECIAKMFGHSEIITS 720
++ + G ++ + D + + + + E + K+ GH++++ S
Sbjct: 257 NEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVIS 306
Score = 41.6 bits (96), Expect = 0.006
Identities = 35/134 (26%), Positives = 63/134 (47%), Gaps = 17/134 (12%)
Query: 112 KSLSALAFSPDGKYIVTGENGHRPAVRIWDVEEKNQVAEMLGHKYGVACVAFSPNMKHIV 171
K++S++ FSP+G+++ + ++IW + + GHK G++ VA+S + +V
Sbjct: 46 KAVSSVKFSPNGEWLASSSADK--LIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLV 103
Query: 172 SMGYQHDMVLNVWDWK-----KDIVVASNKVSCRVIALSFSEDSSYFVTVG-NRHVRFWF 225
S D L +WD K + SN V C +F+ S+ V+ + VR W
Sbjct: 104 SA--SDDKTLKIWDVSSGKCLKTLKGHSNYVFC----CNFNPQSNLIVSGSFDESVRIWD 157
Query: 226 LEVSTETKVTSTVP 239
++ K T+P
Sbjct: 158 VKTG---KCLKTLP 168
Score = 40.4 bits (93), Expect = 0.013
Identities = 32/121 (26%), Positives = 55/121 (45%), Gaps = 13/121 (10%)
Query: 100 ENKQQHIFNTARKSLSALAFSPDGKYIVTGENGHRPAVRIWDVEEKNQVAEMLGHKYGVA 159
+ K + + + +S +A+S D +V+ + ++IWDV + + GH V
Sbjct: 76 DGKFEKTISGHKLGISDVAWSSDSNLLVSASDDK--TLKIWDVSSGKCLKTLKGHSNYVF 133
Query: 160 CVAFSPNMKHIVSMGYQHDMVLNVWDWK-----KDIVVASNKVSCRVIALSFSEDSSYFV 214
C F+P IVS + D + +WD K K + S+ VS A+ F+ D S V
Sbjct: 134 CCNFNPQSNLIVSGSF--DESVRIWDVKTGKCLKTLPAHSDPVS----AVHFNRDGSLIV 187
Query: 215 T 215
+
Sbjct: 188 S 188
Score = 35.4 bits (80), Expect = 0.42
Identities = 19/62 (30%), Positives = 31/62 (50%), Gaps = 2/62 (3%)
Query: 123 GKYIVTGENGHRPAVRIWDVEEKNQVAEMLGHKYGVACVAFSPNMKHIVSMGYQHDMVLN 182
GK+IV+G + V IW+++ K V ++ GH V A P I S ++D +
Sbjct: 271 GKWIVSGSEDN--LVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIK 328
Query: 183 VW 184
+W
Sbjct: 329 LW 330
Score = 34.3 bits (77), Expect = 0.94
Identities = 22/67 (32%), Positives = 33/67 (49%), Gaps = 4/67 (5%)
Query: 119 FSPDGKYIVTGENGHRPAVRIWDVEEKNQVAEMLGHKYGVACVAFSPNMKHIVSMGYQHD 178
F+P IV+G +VRIWDV+ + + H V+ V F+ + IVS Y D
Sbjct: 137 FNPQSNLIVSGSFDE--SVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSY--D 192
Query: 179 MVLNVWD 185
+ +WD
Sbjct: 193 GLCRIWD 199
>gi|16554627 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 63.5 bits (153), Expect = 1e-09
Identities = 50/210 (23%), Positives = 98/210 (46%), Gaps = 17/210 (8%)
Query: 538 LCLEYSKPETGL-----TLLASASRDRLIHVLNVEKNYNLEQTLDDHSSSITAIKFAGNR 592
+ E KPET T +SA++ + V+ NY L+ TL H+ +++++KF+ N
Sbjct: 1 MATEEKKPETEAARAQPTPSSSATQSK---PTPVKPNYALKFTLAGHTKAVSSVKFSPNG 57
Query: 593 DIQMISCGADKSIYFRSAQQGSDGLHFVRTHHVAEKTTLYDMDIDITQKYVAVACQDRNV 652
+ + S ADK I A G F +T K + D+ + A D+ +
Sbjct: 58 E-WLASSSADKLIKIWGAYDGK----FEKTIS-GHKLGISDVAWSSDSNLLVSASDDKTL 111
Query: 653 RVYNTVNGKQKKCYKGSQGDEGSLLKVHVDPSGTFLATSCSDKSISVIDFYSGECIAKMF 712
++++ +GK C K +G + + +P + + D+S+ + D +G+C+ +
Sbjct: 112 KIWDVSSGK---CLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLP 168
Query: 713 GHSEIITSMKFTYDCHHLITVSGDSCVFIW 742
HS+ ++++ F D +++ S D IW
Sbjct: 169 AHSDPVSAVHFNRDGSLIVSSSYDGLCRIW 198
Score = 50.8 bits (120), Expect = 1e-05
Identities = 49/230 (21%), Positives = 98/230 (42%), Gaps = 11/230 (4%)
Query: 492 KAGVRVMQVSPDGQHLASGDRSGNLRIHELHFMDELVKVEAHDAEVLCLEYSKPETGLTL 551
K G+ + S D L S L+I ++ L ++ H V C ++ P++ L
Sbjct: 87 KLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFN-PQSNL-- 143
Query: 552 LASASRDRLIHVLNVEKNYNLEQTLDDHSSSITAIKFAGNRDIQMI-SCGADKSIYFRSA 610
+ S S D + + +V+ L+ TL HS ++A+ F NRD +I S D
Sbjct: 144 IVSGSFDESVRIWDVKTGKCLK-TLPAHSDPVSAVHF--NRDGSLIVSSSYDGLCRIWDT 200
Query: 611 QQGSDGLHFVRTHHVAEKTTLYDMDIDITQKYVAVACQDRNVRVYNTVNGKQKKCYKGSQ 670
G ++T + + + KY+ A D +++++ GK K Y G +
Sbjct: 201 ASGQ----CLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHK 256
Query: 671 GDEGSLLKVHVDPSGTFLATSCSDKSISVIDFYSGECIAKMFGHSEIITS 720
++ + G ++ + D + + + + E + K+ GH++++ S
Sbjct: 257 NEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVIS 306
Score = 41.6 bits (96), Expect = 0.006
Identities = 35/134 (26%), Positives = 63/134 (47%), Gaps = 17/134 (12%)
Query: 112 KSLSALAFSPDGKYIVTGENGHRPAVRIWDVEEKNQVAEMLGHKYGVACVAFSPNMKHIV 171
K++S++ FSP+G+++ + ++IW + + GHK G++ VA+S + +V
Sbjct: 46 KAVSSVKFSPNGEWLASSSADK--LIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLV 103
Query: 172 SMGYQHDMVLNVWDWK-----KDIVVASNKVSCRVIALSFSEDSSYFVTVG-NRHVRFWF 225
S D L +WD K + SN V C +F+ S+ V+ + VR W
Sbjct: 104 SA--SDDKTLKIWDVSSGKCLKTLKGHSNYVFC----CNFNPQSNLIVSGSFDESVRIWD 157
Query: 226 LEVSTETKVTSTVP 239
++ K T+P
Sbjct: 158 VKTG---KCLKTLP 168
Score = 40.4 bits (93), Expect = 0.013
Identities = 32/121 (26%), Positives = 55/121 (45%), Gaps = 13/121 (10%)
Query: 100 ENKQQHIFNTARKSLSALAFSPDGKYIVTGENGHRPAVRIWDVEEKNQVAEMLGHKYGVA 159
+ K + + + +S +A+S D +V+ + ++IWDV + + GH V
Sbjct: 76 DGKFEKTISGHKLGISDVAWSSDSNLLVSASDDK--TLKIWDVSSGKCLKTLKGHSNYVF 133
Query: 160 CVAFSPNMKHIVSMGYQHDMVLNVWDWK-----KDIVVASNKVSCRVIALSFSEDSSYFV 214
C F+P IVS + D + +WD K K + S+ VS A+ F+ D S V
Sbjct: 134 CCNFNPQSNLIVSGSF--DESVRIWDVKTGKCLKTLPAHSDPVS----AVHFNRDGSLIV 187
Query: 215 T 215
+
Sbjct: 188 S 188
Score = 35.4 bits (80), Expect = 0.42
Identities = 19/62 (30%), Positives = 31/62 (50%), Gaps = 2/62 (3%)
Query: 123 GKYIVTGENGHRPAVRIWDVEEKNQVAEMLGHKYGVACVAFSPNMKHIVSMGYQHDMVLN 182
GK+IV+G + V IW+++ K V ++ GH V A P I S ++D +
Sbjct: 271 GKWIVSGSEDN--LVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIK 328
Query: 183 VW 184
+W
Sbjct: 329 LW 330
Score = 34.3 bits (77), Expect = 0.94
Identities = 22/67 (32%), Positives = 33/67 (49%), Gaps = 4/67 (5%)
Query: 119 FSPDGKYIVTGENGHRPAVRIWDVEEKNQVAEMLGHKYGVACVAFSPNMKHIVSMGYQHD 178
F+P IV+G +VRIWDV+ + + H V+ V F+ + IVS Y D
Sbjct: 137 FNPQSNLIVSGSFDE--SVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSY--D 192
Query: 179 MVLNVWD 185
+ +WD
Sbjct: 193 GLCRIWD 199
>gi|223029510 echinoderm microtubule associated protein like 4
isoform b [Homo sapiens]
Length = 923
Score = 60.8 bits (146), Expect = 9e-09
Identities = 46/157 (29%), Positives = 75/157 (47%), Gaps = 15/157 (9%)
Query: 82 TGHVAYLAGCVVVILDPKENKQQHIFNTARKSLSALAFSPDGKYIVTGE------NGH-- 133
TG + Y VVV+ + +E Q+H + LA PD I TG+ +G
Sbjct: 223 TGEIVYFIASVVVLFNYEERTQRHYLGHT-DCVKCLAIHPDKIRIATGQIAGVDKDGRPL 281
Query: 134 RPAVRIWDVEEKN--QVAEMLGHKYGVACVAFSP--NMKHIVSMGYQHDMVLNVWDWKKD 189
+P VR+WD + Q+ + + GV C+ FS + H+ + ++ +L VWDW+K
Sbjct: 282 QPHVRVWDSVTLSTLQIIGLGTFERGVGCLDFSKADSGVHLCVIDDSNEHMLTVWDWQKK 341
Query: 190 IVVASNKVSCRVI-ALSF-SEDSSYFVTVGNRHVRFW 224
A K + V+ A+ F D++ +T G H+ FW
Sbjct: 342 AKGAEIKTTNEVVLAVEFHPTDANTIITCGKSHIFFW 378
Score = 34.3 bits (77), Expect = 0.94
Identities = 45/214 (21%), Positives = 91/214 (42%), Gaps = 15/214 (7%)
Query: 529 KVEAHDAEVLCLEYSKPETGLTLLASASRDRLIHVLNVEKNYNLEQTLDDHSSSITAIKF 588
+++AHD V L + G+ LL +DR I + + + N E + D +I A+
Sbjct: 446 QIKAHDGSVFTL--CQMRNGM-LLTGGGKDRKIILWDHDLNPEREIEVPDQYGTIRAVA- 501
Query: 589 AGNRDIQMISCGADKSIYFRSAQQGSDGLHFVRTHHVAEKTTLYDMDIDITQKYVAVACQ 648
G D ++ G ++ R +DG H E L+ + + + Q
Sbjct: 502 EGKADQFLV--GTSRNFILRGTF--NDGFQIEVQGHTDE---LWGLATHPFKDLLLTCAQ 554
Query: 649 DRNVRVYNTVNGKQKKCYKGSQGDEGSLLKVHVDPSGTFLATSCSDKSISVIDFYSGECI 708
DR V ++N++ + + + + G H PSGT +A V+D + + +
Sbjct: 555 DRQVCLWNSMEHRLE--WTRLVDEPGHCADFH--PSGTVVAIGTHSGRWFVLDAETRDLV 610
Query: 709 AKMFGHSEIITSMKFTYDCHHLITVSGDSCVFIW 742
+ +E ++ M+++ D L S D+ ++++
Sbjct: 611 SIHTDGNEQLSVMRYSIDGTFLAVGSHDNFIYLY 644
Score = 33.9 bits (76), Expect = 1.2
Identities = 24/112 (21%), Positives = 49/112 (43%), Gaps = 8/112 (7%)
Query: 95 ILDPKENKQQHIFNTARKSLSALAFSPDGKYIVTGENGHRPAVRIWDVEEK----NQVAE 150
+LD + I + LS + +S DG ++ G H + ++ V E ++
Sbjct: 601 VLDAETRDLVSIHTDGNEQLSVMRYSIDGTFLAVG--SHDNFIYLYVVSENGRKYSRYGR 658
Query: 151 MLGHKYGVACVAFSPNMKHIVSMGYQHDMVLNVWDWKKDIVVASNKVSCRVI 202
GH + + +SP+ K+I+S ++++ WD + N+ C+ I
Sbjct: 659 CTGHSSYITHLDWSPDNKYIMSNSGDYEIL--YWDIPNGCKLIRNRSDCKDI 708
>gi|19923497 echinoderm microtubule associated protein like 4
isoform a [Homo sapiens]
Length = 981
Score = 60.8 bits (146), Expect = 9e-09
Identities = 46/157 (29%), Positives = 75/157 (47%), Gaps = 15/157 (9%)
Query: 82 TGHVAYLAGCVVVILDPKENKQQHIFNTARKSLSALAFSPDGKYIVTGE------NGH-- 133
TG + Y VVV+ + +E Q+H + LA PD I TG+ +G
Sbjct: 281 TGEIVYFIASVVVLFNYEERTQRHYLGHT-DCVKCLAIHPDKIRIATGQIAGVDKDGRPL 339
Query: 134 RPAVRIWDVEEKN--QVAEMLGHKYGVACVAFSP--NMKHIVSMGYQHDMVLNVWDWKKD 189
+P VR+WD + Q+ + + GV C+ FS + H+ + ++ +L VWDW+K
Sbjct: 340 QPHVRVWDSVTLSTLQIIGLGTFERGVGCLDFSKADSGVHLCVIDDSNEHMLTVWDWQKK 399
Query: 190 IVVASNKVSCRVI-ALSF-SEDSSYFVTVGNRHVRFW 224
A K + V+ A+ F D++ +T G H+ FW
Sbjct: 400 AKGAEIKTTNEVVLAVEFHPTDANTIITCGKSHIFFW 436
Score = 34.3 bits (77), Expect = 0.94
Identities = 45/214 (21%), Positives = 91/214 (42%), Gaps = 15/214 (7%)
Query: 529 KVEAHDAEVLCLEYSKPETGLTLLASASRDRLIHVLNVEKNYNLEQTLDDHSSSITAIKF 588
+++AHD V L + G+ LL +DR I + + + N E + D +I A+
Sbjct: 504 QIKAHDGSVFTL--CQMRNGM-LLTGGGKDRKIILWDHDLNPEREIEVPDQYGTIRAVA- 559
Query: 589 AGNRDIQMISCGADKSIYFRSAQQGSDGLHFVRTHHVAEKTTLYDMDIDITQKYVAVACQ 648
G D ++ G ++ R +DG H E L+ + + + Q
Sbjct: 560 EGKADQFLV--GTSRNFILRGTF--NDGFQIEVQGHTDE---LWGLATHPFKDLLLTCAQ 612
Query: 649 DRNVRVYNTVNGKQKKCYKGSQGDEGSLLKVHVDPSGTFLATSCSDKSISVIDFYSGECI 708
DR V ++N++ + + + + G H PSGT +A V+D + + +
Sbjct: 613 DRQVCLWNSMEHRLE--WTRLVDEPGHCADFH--PSGTVVAIGTHSGRWFVLDAETRDLV 668
Query: 709 AKMFGHSEIITSMKFTYDCHHLITVSGDSCVFIW 742
+ +E ++ M+++ D L S D+ ++++
Sbjct: 669 SIHTDGNEQLSVMRYSIDGTFLAVGSHDNFIYLY 702
Score = 33.9 bits (76), Expect = 1.2
Identities = 24/112 (21%), Positives = 49/112 (43%), Gaps = 8/112 (7%)
Query: 95 ILDPKENKQQHIFNTARKSLSALAFSPDGKYIVTGENGHRPAVRIWDVEEK----NQVAE 150
+LD + I + LS + +S DG ++ G H + ++ V E ++
Sbjct: 659 VLDAETRDLVSIHTDGNEQLSVMRYSIDGTFLAVG--SHDNFIYLYVVSENGRKYSRYGR 716
Query: 151 MLGHKYGVACVAFSPNMKHIVSMGYQHDMVLNVWDWKKDIVVASNKVSCRVI 202
GH + + +SP+ K+I+S ++++ WD + N+ C+ I
Sbjct: 717 CTGHSSYITHLDWSPDNKYIMSNSGDYEIL--YWDIPNGCKLIRNRSDCKDI 766
>gi|94400919 WD repeat domain 90 [Homo sapiens]
Length = 1748
Score = 60.5 bits (145), Expect = 1e-08
Identities = 50/214 (23%), Positives = 91/214 (42%), Gaps = 14/214 (6%)
Query: 62 LEKVLGITAQNSSGLTCDPGTGHVAYLAGCVVVILDPKENKQQHIFNTARKSLSALAFSP 121
L+ V+G + + + P TG AY G +VV+ D QQH ++ +S LA S
Sbjct: 1110 LKAVVGYSGNGRANMVWRPDTGFFAYTCGRLVVVEDLHSGAQQH-WSGHSAEISTLALSH 1168
Query: 122 DGKYIVTGENGHRPA----VRIWDVEEKNQVAEMLGHKYGVACVAFSPNMKHIVSMGYQH 177
+ + + +R+WDV + H V +AFSP+ + +V++G
Sbjct: 1169 SAQVLASASGRSSTTAHCQIRVWDVSGGLCQHLIFPHSTTVLALAFSPDDRLLVTLGDHD 1228
Query: 178 DMVLNVWDWKKDIVVASNKVSCRVIALSFSE-DSSYFVTVGNRHVRFWFL-----EVSTE 231
L +W +V+S ++ V ++F+ D+ VG V FW L ++S +
Sbjct: 1229 GRTLALWGTATYDLVSSTRLPEPVHGVAFNPWDAGELTCVGQGTVTFWLLQQRGADISLQ 1288
Query: 232 TKVTSTVPLVGRSGILGELHNN---IFCGVACGR 262
+ VG + + ++CG + G+
Sbjct: 1289 VRREPVPEAVGAGELTSLCYGAPPLLYCGTSSGQ 1322
Score = 34.7 bits (78), Expect = 0.72
Identities = 23/101 (22%), Positives = 48/101 (47%), Gaps = 4/101 (3%)
Query: 492 KAGVRVMQVSPDGQHLASGDRSGNLRIHELHFMDELVKVEAHDAEVLCLEYSKPETG--- 548
++ V + SP H A+ G++R+ L M+ +++ + + LCL +S P G
Sbjct: 1435 RSKVNEVVFSPGESHCATCSEDGSVRVWALASMELVIQFQVLNQSCLCLAWSPPCCGRPE 1494
Query: 549 LTLLASASRDRLIHVLNVEKNYNLEQTLDDHSSSITAIKFA 589
LA+ D + + +V + +E + H ++T + F+
Sbjct: 1495 QQRLAAGYGDGSLRIFSVSRT-AMELKMHPHPVALTTVAFS 1534
>gi|21071067 TBP-associated factor 5 [Homo sapiens]
Length = 800
Score = 59.3 bits (142), Expect = 3e-08
Identities = 31/101 (30%), Positives = 55/101 (54%), Gaps = 3/101 (2%)
Query: 642 YVAVACQDRNVRVYNTVNGKQKKCYKGSQGDEGSLLKVHVDPSGTFLATSCSDKSISVID 701
YVA DR VR+++ +NG C + G +G + + P+G FLAT +D + + D
Sbjct: 641 YVATGSADRTVRLWDVLNGN---CVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWD 697
Query: 702 FYSGECIAKMFGHSEIITSMKFTYDCHHLITVSGDSCVFIW 742
G + ++ GH++ + S++F+ D L + S D+ V +W
Sbjct: 698 IGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLW 738
Score = 52.8 bits (125), Expect = 3e-06
Identities = 40/199 (20%), Positives = 86/199 (43%), Gaps = 8/199 (4%)
Query: 552 LASASRDRLIHVLNVEKNYNLEQTLDDHSSSITAIKFAGNRDIQMISCGADKSIYFRSAQ 611
L S + + +++ E + LE+ +D+ ++S I + + + S D++ S++
Sbjct: 504 LRSVKQASDLSLIDKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSE 563
Query: 612 QGSDGLHFVRTH-----HVAEKTTLYDMDIDITQKYVAVACQDRNVRVYNTVNGKQKKCY 666
G+ L ++T + ++D Y DR R++ T + + + +
Sbjct: 564 DGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIF 623
Query: 667 KGSQGDEGSLLKVHVDPSGTFLATSCSDKSISVIDFYSGECIAKMFGHSEIITSMKFTYD 726
G D P+ ++AT +D+++ + D +G C+ GH I S+ F+ +
Sbjct: 624 AGHLADVNC---TRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPN 680
Query: 727 CHHLITVSGDSCVFIWHLG 745
L T + D V +W +G
Sbjct: 681 GRFLATGATDGRVLLWDIG 699
Score = 44.7 bits (104), Expect = 7e-04
Identities = 40/139 (28%), Positives = 61/139 (43%), Gaps = 11/139 (7%)
Query: 106 IFNTARKSLSALAFSPDGKYIVTGENGHRPAVRIWDVEEKNQVAEMLGHKYGVACVAFSP 165
IF ++ F P+ Y+ TG VR+WDV N V GHK + + FSP
Sbjct: 622 IFAGHLADVNCTRFHPNSNYVATGSADR--TVRLWDVLNGNCVRIFTGHKGPIHSLTFSP 679
Query: 166 NMKHIVSMGYQHDMVLNVWDWKKDIVVASNK-VSCRVIALSFSEDSSYFVTVG-NRHVRF 223
N + + + G VL +WD ++V K + V +L FS D + + VR
Sbjct: 680 NGRFLAT-GATDGRVL-LWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRL 737
Query: 224 W-----FLEVSTETKVTST 237
W F ++ T+ T+T
Sbjct: 738 WDAIKAFEDLETDDFTTAT 756
Score = 42.4 bits (98), Expect = 0.003
Identities = 38/134 (28%), Positives = 61/134 (45%), Gaps = 10/134 (7%)
Query: 95 ILDPKENKQQHIFNTARKSLSALAFSPDGKYIVTG-ENGHRPAVRIWDVEEKNQVAEMLG 153
I+D K + I + +FSPD Y+++ E+G VR+W ++ + G
Sbjct: 527 IMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDG---TVRLWSLQTFTCLVGYKG 583
Query: 154 HKYGVACVAFSPNMKHIVSMGYQHDMVLNVW--DWKKDIVVASNKVSCRVIALSFSEDSS 211
H Y V FSP + VS G HD V +W D + + + + ++ V F +S+
Sbjct: 584 HNYPVWDTQFSPYGYYFVSGG--HDRVARLWATDHYQPLRIFAGHLA-DVNCTRFHPNSN 640
Query: 212 YFVT-VGNRHVRFW 224
Y T +R VR W
Sbjct: 641 YVATGSADRTVRLW 654
Score = 40.0 bits (92), Expect = 0.017
Identities = 21/67 (31%), Positives = 30/67 (44%), Gaps = 4/67 (5%)
Query: 119 FSPDGKYIVTGENGHRPAVRIWDVEEKNQVAEMLGHKYGVACVAFSPNMKHIVSMGYQHD 178
FSP G Y V+G GH R+W + + GH V C F PN ++ + D
Sbjct: 593 FSPYGYYFVSG--GHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVAT--GSAD 648
Query: 179 MVLNVWD 185
+ +WD
Sbjct: 649 RTVRLWD 655
>gi|216548382 WD repeat domain 47 isoform 3 [Homo sapiens]
Length = 919
Score = 57.8 bits (138), Expect = 8e-08
Identities = 74/282 (26%), Positives = 116/282 (41%), Gaps = 41/282 (14%)
Query: 495 VRVMQVSPDGQHLASGDRSGNLRI-----------HELHFMD--ELVKVEAHDAEVLCLE 541
VR + P G A G S LR+ HE + + H + C+
Sbjct: 609 VRAVAFHPAGGLYAVGSNSKTLRVCAYPDVIDPSAHETPKQPVVRFKRNKHHKGSIYCVA 668
Query: 542 YSKPETGLTLLASASRDRLIHVL--NVEK----NYNLEQTLDDHSSSITAIKFAGNRDIQ 595
+S LLA+ S D+ + VL N E +LE ++ H +I + F +
Sbjct: 669 WSPCGQ---LLATGSNDKYVKVLPFNAETCNATGPDLEFSM--HDGTIRDLAFMEGPESG 723
Query: 596 ---MISCGA-DKSIYFRSAQQGSDGLHFVRTHHVAEKTTLYDMDIDITQKYVAVACQDRN 651
+IS GA D +IY Q+G GLH + + H LY + +A QD+
Sbjct: 724 GAILISAGAGDCNIYTTDCQRGQ-GLHAL-SGHTGHILALYTW----SGWMIASGSQDKT 777
Query: 652 VRVYNTVNGKQKKCYK----GSQGDEGSLLKVHVDPSGTFLATSCSDKSISVIDFYSGEC 707
VR ++ + C + G ++ V VDPSG LAT D S + D G
Sbjct: 778 VRFWDL---RVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLYDIRGGRM 834
Query: 708 IAKMFGHSEIITSMKFTYDCHHLITVSGDSCVFIWHLGPEIT 749
+ HS + S++F+ H+L+T S D + + L ++T
Sbjct: 835 VQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDLQGDLT 876
Score = 37.4 bits (85), Expect = 0.11
Identities = 30/128 (23%), Positives = 57/128 (44%), Gaps = 18/128 (14%)
Query: 107 FNTARKSLSALAFSPDGKYIVTGENGHRPAVRIWDVEEKNQVAEMLGHKYGVACVAFSPN 166
F+ +++++A P G+ + TG+ + ++D+ V H V V FSP
Sbjct: 796 FHGTGSAVASVAVDPSGRLLATGQEDS--SCMLYDIRGGRMVQSYHPHSSDVRSVRFSPG 853
Query: 167 MKHIVSMGYQHDMVLNVWDWKKDI-------VVASNK---VSCRVIALSFSEDSSYFVTV 216
++++ Y DM + V D + D+ VV +K + CR ++D S+ +
Sbjct: 854 AHYLLTGSY--DMKIKVTDLQGDLTKQLPIMVVGEHKDKVIQCR----WHTQDLSFLSSS 907
Query: 217 GNRHVRFW 224
+R V W
Sbjct: 908 ADRTVTLW 915
>gi|216548378 WD repeat domain 47 isoform 1 [Homo sapiens]
Length = 927
Score = 57.8 bits (138), Expect = 8e-08
Identities = 74/282 (26%), Positives = 116/282 (41%), Gaps = 41/282 (14%)
Query: 495 VRVMQVSPDGQHLASGDRSGNLRI-----------HELHFMD--ELVKVEAHDAEVLCLE 541
VR + P G A G S LR+ HE + + H + C+
Sbjct: 617 VRAVAFHPAGGLYAVGSNSKTLRVCAYPDVIDPSAHETPKQPVVRFKRNKHHKGSIYCVA 676
Query: 542 YSKPETGLTLLASASRDRLIHVL--NVEK----NYNLEQTLDDHSSSITAIKFAGNRDIQ 595
+S LLA+ S D+ + VL N E +LE ++ H +I + F +
Sbjct: 677 WSPCGQ---LLATGSNDKYVKVLPFNAETCNATGPDLEFSM--HDGTIRDLAFMEGPESG 731
Query: 596 ---MISCGA-DKSIYFRSAQQGSDGLHFVRTHHVAEKTTLYDMDIDITQKYVAVACQDRN 651
+IS GA D +IY Q+G GLH + + H LY + +A QD+
Sbjct: 732 GAILISAGAGDCNIYTTDCQRGQ-GLHAL-SGHTGHILALYTW----SGWMIASGSQDKT 785
Query: 652 VRVYNTVNGKQKKCYK----GSQGDEGSLLKVHVDPSGTFLATSCSDKSISVIDFYSGEC 707
VR ++ + C + G ++ V VDPSG LAT D S + D G
Sbjct: 786 VRFWDL---RVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLYDIRGGRM 842
Query: 708 IAKMFGHSEIITSMKFTYDCHHLITVSGDSCVFIWHLGPEIT 749
+ HS + S++F+ H+L+T S D + + L ++T
Sbjct: 843 VQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDLQGDLT 884
Score = 37.4 bits (85), Expect = 0.11
Identities = 30/128 (23%), Positives = 57/128 (44%), Gaps = 18/128 (14%)
Query: 107 FNTARKSLSALAFSPDGKYIVTGENGHRPAVRIWDVEEKNQVAEMLGHKYGVACVAFSPN 166
F+ +++++A P G+ + TG+ + ++D+ V H V V FSP
Sbjct: 804 FHGTGSAVASVAVDPSGRLLATGQEDS--SCMLYDIRGGRMVQSYHPHSSDVRSVRFSPG 861
Query: 167 MKHIVSMGYQHDMVLNVWDWKKDI-------VVASNK---VSCRVIALSFSEDSSYFVTV 216
++++ Y DM + V D + D+ VV +K + CR ++D S+ +
Sbjct: 862 AHYLLTGSY--DMKIKVTDLQGDLTKQLPIMVVGEHKDKVIQCR----WHTQDLSFLSSS 915
Query: 217 GNRHVRFW 224
+R V W
Sbjct: 916 ADRTVTLW 923
>gi|216548347 WD repeat domain 47 isoform 2 [Homo sapiens]
Length = 920
Score = 57.8 bits (138), Expect = 8e-08
Identities = 74/282 (26%), Positives = 116/282 (41%), Gaps = 41/282 (14%)
Query: 495 VRVMQVSPDGQHLASGDRSGNLRI-----------HELHFMD--ELVKVEAHDAEVLCLE 541
VR + P G A G S LR+ HE + + H + C+
Sbjct: 610 VRAVAFHPAGGLYAVGSNSKTLRVCAYPDVIDPSAHETPKQPVVRFKRNKHHKGSIYCVA 669
Query: 542 YSKPETGLTLLASASRDRLIHVL--NVEK----NYNLEQTLDDHSSSITAIKFAGNRDIQ 595
+S LLA+ S D+ + VL N E +LE ++ H +I + F +
Sbjct: 670 WSPCGQ---LLATGSNDKYVKVLPFNAETCNATGPDLEFSM--HDGTIRDLAFMEGPESG 724
Query: 596 ---MISCGA-DKSIYFRSAQQGSDGLHFVRTHHVAEKTTLYDMDIDITQKYVAVACQDRN 651
+IS GA D +IY Q+G GLH + + H LY + +A QD+
Sbjct: 725 GAILISAGAGDCNIYTTDCQRGQ-GLHAL-SGHTGHILALYTW----SGWMIASGSQDKT 778
Query: 652 VRVYNTVNGKQKKCYK----GSQGDEGSLLKVHVDPSGTFLATSCSDKSISVIDFYSGEC 707
VR ++ + C + G ++ V VDPSG LAT D S + D G
Sbjct: 779 VRFWDL---RVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLYDIRGGRM 835
Query: 708 IAKMFGHSEIITSMKFTYDCHHLITVSGDSCVFIWHLGPEIT 749
+ HS + S++F+ H+L+T S D + + L ++T
Sbjct: 836 VQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDLQGDLT 877
Score = 37.4 bits (85), Expect = 0.11
Identities = 30/128 (23%), Positives = 57/128 (44%), Gaps = 18/128 (14%)
Query: 107 FNTARKSLSALAFSPDGKYIVTGENGHRPAVRIWDVEEKNQVAEMLGHKYGVACVAFSPN 166
F+ +++++A P G+ + TG+ + ++D+ V H V V FSP
Sbjct: 797 FHGTGSAVASVAVDPSGRLLATGQEDS--SCMLYDIRGGRMVQSYHPHSSDVRSVRFSPG 854
Query: 167 MKHIVSMGYQHDMVLNVWDWKKDI-------VVASNK---VSCRVIALSFSEDSSYFVTV 216
++++ Y DM + V D + D+ VV +K + CR ++D S+ +
Sbjct: 855 AHYLLTGSY--DMKIKVTDLQGDLTKQLPIMVVGEHKDKVIQCR----WHTQDLSFLSSS 908
Query: 217 GNRHVRFW 224
+R V W
Sbjct: 909 ADRTVTLW 916
>gi|110227615 echinoderm microtubule associated protein like 3 [Homo
sapiens]
Length = 896
Score = 57.8 bits (138), Expect = 8e-08
Identities = 59/211 (27%), Positives = 94/211 (44%), Gaps = 24/211 (11%)
Query: 60 VSLEKVLGITAQNSSGLTCDPGTGHVAYLAGCVVVILDPKENK-------QQHIFNTARK 112
+SL+ V G ++S +G V Y CVVV+ P Q+H +
Sbjct: 248 LSLDWVYGYRGRDSRSNLFVLRSGEVVYFIACVVVLYRPGGGPGGPGGGGQRH-YRGHTD 306
Query: 113 SLSALAFSPDGKYIVTGENGH--------RPAVRIWDVEEKNQVAEM-LG-HKYGVACVA 162
+ LA PDG + +G+ +P V IWD E ++ E+ LG + GV +A
Sbjct: 307 CVRCLAVHPDGVRVASGQTAGVDKDGKPLQPVVHIWDSETLLKLQEIGLGAFERGVGALA 366
Query: 163 FSPNMK--HIVSMGYQHDMVLNVWDWKKDIVVASNK-VSCRVIALSFS-EDSSYFVTVGN 218
FS + + + ++ +L+VWD + + +A K + V+A+ F+ DSS VT G
Sbjct: 367 FSAADQGAFLCVVDDSNEHMLSVWDCSRGMKLAEIKSTNDSVLAVGFNPRDSSCIVTSGK 426
Query: 219 RHVRFWFLEVSTETKVTSTVPLVGRSGILGE 249
HV FW S V L + G+ G+
Sbjct: 427 SHVHFW--NWSGGVGVPGNGTLTRKQGVFGK 455
Score = 33.9 bits (76), Expect = 1.2
Identities = 13/33 (39%), Positives = 23/33 (69%), Gaps = 1/33 (3%)
Query: 713 GHSEIITSMKFTYDCHHLITVSG-DSCVFIWHL 744
GH +TS++FT+D HL+++ G D+ +F W +
Sbjct: 837 GHGSHVTSVRFTHDDSHLVSLGGKDASIFQWRV 869
Score = 32.0 bits (71), Expect = 4.7
Identities = 19/68 (27%), Positives = 30/68 (44%), Gaps = 4/68 (5%)
Query: 679 VHVDPSGTFLATSCSDKSISVIDFYSGECIAKMFG----HSEIITSMKFTYDCHHLITVS 734
V P G +LA D I + S + FG HS IT + ++ D + +++ S
Sbjct: 686 VRYSPDGLYLAIGSHDNVIYIYSVSSDGAKSSRFGRCMGHSSFITHLDWSKDGNFIMSNS 745
Query: 735 GDSCVFIW 742
GD + W
Sbjct: 746 GDYEILYW 753
>gi|31377846 WD repeat domain 52 [Homo sapiens]
Length = 982
Score = 57.0 bits (136), Expect = 1e-07
Identities = 34/141 (24%), Positives = 67/141 (47%), Gaps = 3/141 (2%)
Query: 87 YLAGCVVVILDPKENKQQHIFNTARKSLSALAFSPDGKYIVTGENGHRPAVRIWDVEEKN 146
Y+AG ++ L+ K +Q ++ +++ + + + P Y E G P + I++
Sbjct: 159 YIAGNQLIFLNLKTKEQIYLRSSSGEGIGVIGVHPHKTYFTVAEKGSFPDIIIYEYPSLR 218
Query: 147 QVAEML-GHKYGVACVAFSPNMKHIVSMGYQHDMVLNVWDWKKDIVVASNKV-SCRVIAL 204
+ G + G A V F+ + + S+G D L +W+WK++ + K S V +
Sbjct: 219 PYRVLRDGTEKGYAYVDFNYSGNLLASVGSNPDYTLTIWNWKEEQPILRTKAFSQEVFKV 278
Query: 205 SFSED-SSYFVTVGNRHVRFW 224
+F+ D T G+ H++FW
Sbjct: 279 TFNPDKEEQLTTSGSGHIKFW 299
>gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens]
Length = 369
Score = 56.2 bits (134), Expect = 2e-07
Identities = 55/251 (21%), Positives = 103/251 (41%), Gaps = 13/251 (5%)
Query: 492 KAGVRVMQVSPDGQHLASGDRSGNLRIHELHFMDELVKVEAHDAEVLCLEYSKPETGLTL 551
K V + SP G LASG R +RI + E AH A V + +
Sbjct: 23 KDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFV- 81
Query: 552 LASASRDRLIHVLNVEKNYNLEQTLDDHSSSITAIKFAGNRDIQMISCGADKSIYFRSAQ 611
+AS D+ + V + L +L H + + KF+ + + ++S DK++ +
Sbjct: 82 --TASDDKTVKVWATHRQKFLF-SLSQHINWVRCAKFSPDGRL-IVSASDDKTVKLWD-K 136
Query: 612 QGSDGLHFVRTHHVAEKTTLYDMDIDITQKYVAVACQDRNVRVYNTVNGKQKKCYKGSQG 671
+ +H H + +D + +A A D V+V++ + + Y Q
Sbjct: 137 SSRECVHSYCEHG----GFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHY---QL 189
Query: 672 DEGSLLKVHVDPSGTFLATSCSDKSISVIDFYSGECIAKMFGHSEIITSMKFTYDCHHLI 731
++ + PSG +L T+ SD ++ ++D G + + GH T++ F+ +
Sbjct: 190 HSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFA 249
Query: 732 TVSGDSCVFIW 742
+ D V +W
Sbjct: 250 SGGSDEQVMVW 260
Score = 41.2 bits (95), Expect = 0.008
Identities = 46/213 (21%), Positives = 89/213 (41%), Gaps = 15/213 (7%)
Query: 533 HDAEVLCLEYSKPETGLTLLASASRDRLIHVLNVEKNYNLEQTL-DDHSSSITAIKFAGN 591
H V C+ +S LLAS SRD+ + + N E T+ H++++ ++ F +
Sbjct: 22 HKDAVTCVNFSPSGH---LLASGSRDKTVRIW--VPNVKGESTVFRAHTATVRSVHFCSD 76
Query: 592 RDIQMISCGADKSIYFRSAQQGSDGLHFVRTHHVAEKTTLYDMDIDITQKYVAVACQDRN 651
++ DK++ + + L + H + + D + + A D+
Sbjct: 77 GQ-SFVTASDDKTVKVWATHR-QKFLFSLSQHINWVRCAKFSPD----GRLIVSASDDKT 130
Query: 652 VRVYNTVNGKQKKCYKGSQGDEGSLLKVHVDPSGTFLATSCSDKSISVIDFYSGECIAKM 711
V++++ ++C G + V PSGT +A + D ++ V D + +
Sbjct: 131 VKLWDK---SSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHY 187
Query: 712 FGHSEIITSMKFTYDCHHLITVSGDSCVFIWHL 744
HS + + F ++LIT S DS + I L
Sbjct: 188 QLHSAAVNGLSFHPSGNYLITASSDSTLKILDL 220
Score = 35.4 bits (80), Expect = 0.42
Identities = 25/99 (25%), Positives = 46/99 (46%), Gaps = 4/99 (4%)
Query: 93 VVILDPKENKQQHIFNTARKSLSALAFSPDGKYIVTGENGHRPAVRIWDVEEKNQVAEML 152
V + D + ++ + +++ L+F P G Y++T + ++I D+ E + +
Sbjct: 173 VKVWDVRTHRLLQHYQLHSAAVNGLSFHPSGNYLITASSD--STLKILDLMEGRLLYTLH 230
Query: 153 GHKYGVACVAFSPNMKHIVSMGYQHDMVLNVWDWKKDIV 191
GH+ VAFS ++ S G D + VW DIV
Sbjct: 231 GHQGPATTVAFSRTGEYFASGG--SDEQVMVWKSNFDIV 267
Score = 35.0 bits (79), Expect = 0.55
Identities = 23/88 (26%), Positives = 41/88 (46%), Gaps = 4/88 (4%)
Query: 139 IWDVEEKNQVAEMLGHKYGVACVAFSPNMKHIVSMGYQHDMVLNVW-DWKKDIVVASNKV 197
+W ++ +++ GHK V CV FSP+ H+++ G D + +W K
Sbjct: 7 VWHMKPQSRAYRFTGHKDAVTCVNFSPS-GHLLASG-SRDKTVRIWVPNVKGESTVFRAH 64
Query: 198 SCRVIALSFSEDSSYFVTVG-NRHVRFW 224
+ V ++ F D FVT ++ V+ W
Sbjct: 65 TATVRSVHFCSDGQSFVTASDDKTVKVW 92
Score = 35.0 bits (79), Expect = 0.55
Identities = 21/88 (23%), Positives = 38/88 (43%), Gaps = 4/88 (4%)
Query: 98 PKENKQQHIFNTARKSLSALAFSPDGKYIVTGENGHRPAVRIWDVEEKNQVAEMLGHKYG 157
P + +F ++ ++ F DG+ VT + V++W + + + H
Sbjct: 52 PNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDK--TVKVWATHRQKFLFSLSQHINW 109
Query: 158 VACVAFSPNMKHIVSMGYQHDMVLNVWD 185
V C FSP+ + IVS D + +WD
Sbjct: 110 VRCAKFSPDGRLIVSA--SDDKTVKLWD 135
Score = 34.3 bits (77), Expect = 0.94
Identities = 22/82 (26%), Positives = 39/82 (47%), Gaps = 3/82 (3%)
Query: 662 QKKCYKGSQGDEGSLLKVHVDPSGTFLATSCSDKSISV-IDFYSGECIAKMFGHSEIITS 720
Q + Y+ + G + ++ V+ PSG LA+ DK++ + + GE H+ + S
Sbjct: 13 QSRAYRFT-GHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTV-FRAHTATVRS 70
Query: 721 MKFTYDCHHLITVSGDSCVFIW 742
+ F D +T S D V +W
Sbjct: 71 VHFCSDGQSFVTASDDKTVKVW 92
>gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens]
Length = 359
Score = 56.2 bits (134), Expect = 2e-07
Identities = 55/251 (21%), Positives = 103/251 (41%), Gaps = 13/251 (5%)
Query: 492 KAGVRVMQVSPDGQHLASGDRSGNLRIHELHFMDELVKVEAHDAEVLCLEYSKPETGLTL 551
K V + SP G LASG R +RI + E AH A V + +
Sbjct: 61 KDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFV- 119
Query: 552 LASASRDRLIHVLNVEKNYNLEQTLDDHSSSITAIKFAGNRDIQMISCGADKSIYFRSAQ 611
+AS D+ + V + L +L H + + KF+ + + ++S DK++ +
Sbjct: 120 --TASDDKTVKVWATHRQKFLF-SLSQHINWVRCAKFSPDGRL-IVSASDDKTVKLWD-K 174
Query: 612 QGSDGLHFVRTHHVAEKTTLYDMDIDITQKYVAVACQDRNVRVYNTVNGKQKKCYKGSQG 671
+ +H H + +D + +A A D V+V++ + + Y Q
Sbjct: 175 SSRECVHSYCEHG----GFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHY---QL 227
Query: 672 DEGSLLKVHVDPSGTFLATSCSDKSISVIDFYSGECIAKMFGHSEIITSMKFTYDCHHLI 731
++ + PSG +L T+ SD ++ ++D G + + GH T++ F+ +
Sbjct: 228 HSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFA 287
Query: 732 TVSGDSCVFIW 742
+ D V +W
Sbjct: 288 SGGSDEQVMVW 298
Score = 47.4 bits (111), Expect = 1e-04
Identities = 53/251 (21%), Positives = 102/251 (40%), Gaps = 15/251 (5%)
Query: 495 VRVMQVSPDGQHLASGDRSGNLRIHELHFMDELVKVEAHDAEVLCLEYSKPETGLTLLAS 554
V + S + + LASG L + + + H V C+ +S LLAS
Sbjct: 22 VTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGH---LLAS 78
Query: 555 ASRDRLIHVLNVEKNYNLEQTL-DDHSSSITAIKFAGNRDIQMISCGADKSIYFRSAQQG 613
SRD+ + + N E T+ H++++ ++ F + ++ DK++ + +
Sbjct: 79 GSRDKTVRIW--VPNVKGESTVFRAHTATVRSVHFCSDGQ-SFVTASDDKTVKVWATHR- 134
Query: 614 SDGLHFVRTHHVAEKTTLYDMDIDITQKYVAVACQDRNVRVYNTVNGKQKKCYKGSQGDE 673
L + H + + D + + A D+ V++++ ++C
Sbjct: 135 QKFLFSLSQHINWVRCAKFSPD----GRLIVSASDDKTVKLWDK---SSRECVHSYCEHG 187
Query: 674 GSLLKVHVDPSGTFLATSCSDKSISVIDFYSGECIAKMFGHSEIITSMKFTYDCHHLITV 733
G + V PSGT +A + D ++ V D + + HS + + F ++LIT
Sbjct: 188 GFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLSFHPSGNYLITA 247
Query: 734 SGDSCVFIWHL 744
S DS + I L
Sbjct: 248 SSDSTLKILDL 258
Score = 38.9 bits (89), Expect = 0.038
Identities = 29/120 (24%), Positives = 55/120 (45%), Gaps = 6/120 (5%)
Query: 107 FNTARKSLSALAFSPDGKYIVTGENGHRPAVRIWDVEEKNQVAEMLGHKYGVACVAFSPN 166
F R +++ + FS + K + +G + +W ++ +++ GHK V CV FSP+
Sbjct: 15 FKGHRDAVTCVDFSINTKQLASGSMDS--CLMVWHMKPQSRAYRFTGHKDAVTCVNFSPS 72
Query: 167 MKHIVSMGYQHDMVLNVW-DWKKDIVVASNKVSCRVIALSFSEDSSYFVTVG-NRHVRFW 224
H+++ G D + +W K + V ++ F D FVT ++ V+ W
Sbjct: 73 -GHLLASG-SRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVW 130
Score = 35.4 bits (80), Expect = 0.42
Identities = 25/99 (25%), Positives = 46/99 (46%), Gaps = 4/99 (4%)
Query: 93 VVILDPKENKQQHIFNTARKSLSALAFSPDGKYIVTGENGHRPAVRIWDVEEKNQVAEML 152
V + D + ++ + +++ L+F P G Y++T + ++I D+ E + +
Sbjct: 211 VKVWDVRTHRLLQHYQLHSAAVNGLSFHPSGNYLITASSD--STLKILDLMEGRLLYTLH 268
Query: 153 GHKYGVACVAFSPNMKHIVSMGYQHDMVLNVWDWKKDIV 191
GH+ VAFS ++ S G D + VW DIV
Sbjct: 269 GHQGPATTVAFSRTGEYFASGG--SDEQVMVWKSNFDIV 305
Score = 35.0 bits (79), Expect = 0.55
Identities = 12/35 (34%), Positives = 22/35 (62%)
Query: 713 GHSEIITSMKFTYDCHHLITVSGDSCVFIWHLGPE 747
GH + +T + F+ + L + S DSC+ +WH+ P+
Sbjct: 17 GHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQ 51
Score = 35.0 bits (79), Expect = 0.55
Identities = 21/88 (23%), Positives = 38/88 (43%), Gaps = 4/88 (4%)
Query: 98 PKENKQQHIFNTARKSLSALAFSPDGKYIVTGENGHRPAVRIWDVEEKNQVAEMLGHKYG 157
P + +F ++ ++ F DG+ VT + V++W + + + H
Sbjct: 90 PNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDK--TVKVWATHRQKFLFSLSQHINW 147
Query: 158 VACVAFSPNMKHIVSMGYQHDMVLNVWD 185
V C FSP+ + IVS D + +WD
Sbjct: 148 VRCAKFSPDGRLIVSA--SDDKTVKLWD 173
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.132 0.399
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 68,653,043
Number of Sequences: 37866
Number of extensions: 3778384
Number of successful extensions: 25694
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 114
Number of HSP's successfully gapped in prelim test: 583
Number of HSP's that attempted gapping in prelim test: 21136
Number of HSP's gapped (non-prelim): 4856
length of query: 1518
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1403
effective length of database: 13,892,928
effective search space: 19491777984
effective search space used: 19491777984
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.