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Search of human proteins with 145309298
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|145309298 coiled-coil domain containing 16 [Homo sapiens]
(372 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|145309298 coiled-coil domain containing 16 [Homo sapiens] 734 0.0
gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap... 58 1e-08
gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens] 58 1e-08
gi|4502805 chromogranin A precursor [Homo sapiens] 50 4e-06
gi|4759208 TAO kinase 2 isoform 1 [Homo sapiens] 46 5e-05
gi|45505130 TAO kinase 2 isoform 2 [Homo sapiens] 46 5e-05
gi|48255883 troponin T type 2, cardiac isoform 4 [Homo sapiens] 46 6e-05
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 46 6e-05
gi|4826870 nucleobindin 2 [Homo sapiens] 45 8e-05
gi|92859701 myosin VI [Homo sapiens] 44 2e-04
gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens] 44 2e-04
gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens] 44 2e-04
gi|195976782 Paf1/RNA polymerase II complex component [Homo sapi... 44 2e-04
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)... 44 3e-04
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 43 4e-04
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 43 4e-04
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 43 4e-04
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 43 4e-04
gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isof... 43 4e-04
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 43 4e-04
gi|116174778 centrosome spindle pole associated protein 1 isofor... 43 5e-04
gi|116174789 centrosome spindle pole associated protein 1 isofor... 43 5e-04
gi|48255879 troponin T type 2, cardiac isoform 2 [Homo sapiens] 42 7e-04
gi|48255877 troponin T type 2, cardiac isoform 1 [Homo sapiens] 42 7e-04
gi|48255881 troponin T type 2, cardiac isoform 3 [Homo sapiens] 42 9e-04
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 42 9e-04
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 42 9e-04
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 42 9e-04
gi|15149463 caldesmon 1 isoform 4 [Homo sapiens] 42 9e-04
gi|15149467 caldesmon 1 isoform 3 [Homo sapiens] 42 9e-04
>gi|145309298 coiled-coil domain containing 16 [Homo sapiens]
Length = 372
Score = 734 bits (1895), Expect = 0.0
Identities = 372/372 (100%), Positives = 372/372 (100%)
Query: 1 MASSASARTPAGKRVINQEELRRLMKEKQRLSTSRKRIESPFAKYNRLGQLSCALCNTPV 60
MASSASARTPAGKRVINQEELRRLMKEKQRLSTSRKRIESPFAKYNRLGQLSCALCNTPV
Sbjct: 1 MASSASARTPAGKRVINQEELRRLMKEKQRLSTSRKRIESPFAKYNRLGQLSCALCNTPV 60
Query: 61 KSELLWQTHVLGKQHREKVAELKGAKEASQGSSASSAPHSVKRKAPDADDQDVKRAKATL 120
KSELLWQTHVLGKQHREKVAELKGAKEASQGSSASSAPHSVKRKAPDADDQDVKRAKATL
Sbjct: 61 KSELLWQTHVLGKQHREKVAELKGAKEASQGSSASSAPHSVKRKAPDADDQDVKRAKATL 120
Query: 121 VPQVQPSTSAWTTNFDKIGKEFIRATPSKPSGLSLLPDYEDEEEEEEEEEGDGERKRGDA 180
VPQVQPSTSAWTTNFDKIGKEFIRATPSKPSGLSLLPDYEDEEEEEEEEEGDGERKRGDA
Sbjct: 121 VPQVQPSTSAWTTNFDKIGKEFIRATPSKPSGLSLLPDYEDEEEEEEEEEGDGERKRGDA 180
Query: 181 SKPLSDAQGKEHSVSSSREVTSSVLPNDFFSTNPPKAPIIPHSGSIEKAEIHEKVVERRE 240
SKPLSDAQGKEHSVSSSREVTSSVLPNDFFSTNPPKAPIIPHSGSIEKAEIHEKVVERRE
Sbjct: 181 SKPLSDAQGKEHSVSSSREVTSSVLPNDFFSTNPPKAPIIPHSGSIEKAEIHEKVVERRE 240
Query: 241 NTAEALPEGFFDDPEVDARVRKVDAPKDQMDKEWDEFQKAMRQVNTISEAIVAEEDEEGR 300
NTAEALPEGFFDDPEVDARVRKVDAPKDQMDKEWDEFQKAMRQVNTISEAIVAEEDEEGR
Sbjct: 241 NTAEALPEGFFDDPEVDARVRKVDAPKDQMDKEWDEFQKAMRQVNTISEAIVAEEDEEGR 300
Query: 301 LDRQIGEIDEQIECYRRVEKLRNRQDEIKNKLKEILTIKELQKKEEENADSDDEGELQDL 360
LDRQIGEIDEQIECYRRVEKLRNRQDEIKNKLKEILTIKELQKKEEENADSDDEGELQDL
Sbjct: 301 LDRQIGEIDEQIECYRRVEKLRNRQDEIKNKLKEILTIKELQKKEEENADSDDEGELQDL 360
Query: 361 LSQDWRVKGALL 372
LSQDWRVKGALL
Sbjct: 361 LSQDWRVKGALL 372
>gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo
sapiens]
Length = 1116
Score = 58.2 bits (139), Expect = 1e-08
Identities = 67/267 (25%), Positives = 122/267 (45%), Gaps = 38/267 (14%)
Query: 111 QDVKRAKATLVPQVQPSTSAWTTNFDKIGKEFIRATPSKPSGLSLLPDYEDEEEEEEEEE 170
+D ++ ++L +V+ S A TTN D A K + L + D +E E++EE
Sbjct: 588 RDKEKQMSSLKERVK-SLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEE 646
Query: 171 GDGERK------------RGDAS-KPLSDAQGKEH--SVSSSREVTSSVLPNDFFSTNPP 215
D +K +GD S K S KEH S++SS S L +
Sbjct: 647 IDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQK 706
Query: 216 KAPIIPHSGSIEKAEIHEKVVERRENTAEALPEGFFDDPEVDARVRKVDAPKDQMDKEWD 275
K + ++KA HE +E R + PE+ R++ ++ ++ + D
Sbjct: 707 KEECLKMESQLKKA--HEAALEARAS------------PEMSDRIQHLER---EITRYKD 749
Query: 276 EFQKAMRQVNTISEAIVAEEDEEGRLDRQIGEIDEQI-ECYRRVEKLRNRQDEIKNKLKE 334
E KA +V+ + E + E+E+ D++I E++ Q+ + ++V L++++ K K +
Sbjct: 750 ESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQ 809
Query: 335 ILTIKELQKKEEENADSDDEGELQDLL 361
+L E ++ E+N +D +LQD L
Sbjct: 810 ML---EEARRREDNL-NDSSQQLQDSL 832
>gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]
Length = 1088
Score = 58.2 bits (139), Expect = 1e-08
Identities = 67/267 (25%), Positives = 122/267 (45%), Gaps = 38/267 (14%)
Query: 111 QDVKRAKATLVPQVQPSTSAWTTNFDKIGKEFIRATPSKPSGLSLLPDYEDEEEEEEEEE 170
+D ++ ++L +V+ S A TTN D A K + L + D +E E++EE
Sbjct: 560 RDKEKQMSSLKERVK-SLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEE 618
Query: 171 GDGERK------------RGDAS-KPLSDAQGKEH--SVSSSREVTSSVLPNDFFSTNPP 215
D +K +GD S K S KEH S++SS S L +
Sbjct: 619 IDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQK 678
Query: 216 KAPIIPHSGSIEKAEIHEKVVERRENTAEALPEGFFDDPEVDARVRKVDAPKDQMDKEWD 275
K + ++KA HE +E R + PE+ R++ ++ ++ + D
Sbjct: 679 KEECLKMESQLKKA--HEAALEARAS------------PEMSDRIQHLER---EITRYKD 721
Query: 276 EFQKAMRQVNTISEAIVAEEDEEGRLDRQIGEIDEQI-ECYRRVEKLRNRQDEIKNKLKE 334
E KA +V+ + E + E+E+ D++I E++ Q+ + ++V L++++ K K +
Sbjct: 722 ESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQ 781
Query: 335 ILTIKELQKKEEENADSDDEGELQDLL 361
+L E ++ E+N +D +LQD L
Sbjct: 782 ML---EEARRREDNL-NDSSQQLQDSL 804
>gi|4502805 chromogranin A precursor [Homo sapiens]
Length = 457
Score = 49.7 bits (117), Expect = 4e-06
Identities = 78/385 (20%), Positives = 160/385 (41%), Gaps = 45/385 (11%)
Query: 13 KRVINQEELRRLMKEKQRLST--SRKRIESPFAKYNRLGQLSCALCNTPVKSELLWQTH- 69
+R+++ + L+KE Q L+ +++R +LS L N ++EL
Sbjct: 64 ERILSILRHQNLLKELQDLALQGAKERAHQQKKHSGFEDELSEVLENQSSQAELKEAVEE 123
Query: 70 -----VLGKQHREKVAELKGAKEASQGSSASSAPHSVKR-------KAPDADDQDVKRAK 117
V+ K+ K AE G EA+ G+ + P ++ +AP ++++ + A
Sbjct: 124 PSSKDVMEKREDSKEAEKSG--EATDGARPQALPEPMQESKAEGNNQAPGEEEEEEEEAT 181
Query: 118 ATLVPQVQPSTSAWTTNFDKIGKEFIRATPSKPSGLSLLPDYEDEEEEEEEEEGDGERKR 177
T P PS + + + + GLS P ++ + EEEEEEE + E
Sbjct: 182 NTHPPASLPSQKYPGPQAEGDSEGLSQGLVDREKGLSAEPGWQAKREEEEEEEEEAE--A 239
Query: 178 GDASKPLSDAQG---KEHSVSSSREVTSSVLPNDFFSTNPPKAPIIPHSGSIE-KAEIHE 233
G+ + P + H +E+ ++ + + P + E K E
Sbjct: 240 GEEAVPEEEGPTVVLNPHPSLGYKEIRKGESRSEALAVDGAGKPGAEEAQDPEGKGEQEH 299
Query: 234 KVVERRENTAEALPEGFFDDPEVDARVRKVDAPKDQMDKEWDEFQKAMRQVNTISEAIVA 293
+ E +P+G F + +++ ++++ KEW++ K +++ +++ + A
Sbjct: 300 SQQKEEEEEMAVVPQGLFR----GGKSGELEQEEERLSKEWED-SKRWSKMDQLAKELTA 354
Query: 294 E------EDEEGRLDRQIGEIDEQIECY---------RRVEKLRNRQDEIKNKLK-EILT 337
E E+EE D + ++ + Y RR + +R+D ++ L ++
Sbjct: 355 EKRLEGQEEEEDNRDSSM-KLSFRARAYGFRGPGPQLRRGWRPSSREDSLEAGLPLQVRG 413
Query: 338 IKELQKKEEENADSDDEGELQDLLS 362
E +K+EE +A+ E + + LS
Sbjct: 414 YPEEKKEEEGSANRRPEDQELESLS 438
>gi|4759208 TAO kinase 2 isoform 1 [Homo sapiens]
Length = 1049
Score = 46.2 bits (108), Expect = 5e-05
Identities = 56/255 (21%), Positives = 106/255 (41%), Gaps = 34/255 (13%)
Query: 148 SKPSGLSLLPDYEDEEEEEEEEEGDGERKRGDASKPLSDAQGKEHSVSSSREVTSSVLPN 207
S+ S ++ L D D EEEEEEEE + E + G ++ ++ Q EH+V+S + + +
Sbjct: 363 SQSSSVNSLADASDNEEEEEEEEEEEEEEEGPEAREMAMMQEGEHTVTSHSSIIHRLPGS 422
Query: 208 DFFSTNPPKAPIIP----------------------------HSGSIEKAEIHEKVVERR 239
D +P + I P H +I A + + ++
Sbjct: 423 DNLYDDPYQPEITPSPLQPPAAPAPTSTTSSARRRAYCRNRDHFATIRTASLVSRQIQEH 482
Query: 240 ENTAEALPEGFFDDPEVDARVRK-VDAPKDQMDKEWDEFQ-KAMRQVNTISEAIVAEEDE 297
E + AL E + + +K + A + ++ E +E + R++ AE ++
Sbjct: 483 EQDS-ALREQLSGYKRMRRQHQKQLLALESRLRGEREEHSARLQRELEAQRAGFGAEAEK 541
Query: 298 EGRLDRQIGEIDEQIECYRRVEKLRNRQDEIKNKLKEILTIKELQKKEEENADSDDEGEL 357
R + IGE + + + E+ + +Q + + KE+ + E QK+ + + EL
Sbjct: 542 LARRHQAIGEKEARAA---QAEERKFQQHILGQQKKELAALLEAQKRTYKLRKEQLKEEL 598
Query: 358 QDLLSQDWRVKGALL 372
Q+ S R K L
Sbjct: 599 QENPSTPKREKAEWL 613
>gi|45505130 TAO kinase 2 isoform 2 [Homo sapiens]
Length = 1235
Score = 46.2 bits (108), Expect = 5e-05
Identities = 56/255 (21%), Positives = 106/255 (41%), Gaps = 34/255 (13%)
Query: 148 SKPSGLSLLPDYEDEEEEEEEEEGDGERKRGDASKPLSDAQGKEHSVSSSREVTSSVLPN 207
S+ S ++ L D D EEEEEEEE + E + G ++ ++ Q EH+V+S + + +
Sbjct: 363 SQSSSVNSLADASDNEEEEEEEEEEEEEEEGPEAREMAMMQEGEHTVTSHSSIIHRLPGS 422
Query: 208 DFFSTNPPKAPIIP----------------------------HSGSIEKAEIHEKVVERR 239
D +P + I P H +I A + + ++
Sbjct: 423 DNLYDDPYQPEITPSPLQPPAAPAPTSTTSSARRRAYCRNRDHFATIRTASLVSRQIQEH 482
Query: 240 ENTAEALPEGFFDDPEVDARVRK-VDAPKDQMDKEWDEFQ-KAMRQVNTISEAIVAEEDE 297
E + AL E + + +K + A + ++ E +E + R++ AE ++
Sbjct: 483 EQDS-ALREQLSGYKRMRRQHQKQLLALESRLRGEREEHSARLQRELEAQRAGFGAEAEK 541
Query: 298 EGRLDRQIGEIDEQIECYRRVEKLRNRQDEIKNKLKEILTIKELQKKEEENADSDDEGEL 357
R + IGE + + + E+ + +Q + + KE+ + E QK+ + + EL
Sbjct: 542 LARRHQAIGEKEARAA---QAEERKFQQHILGQQKKELAALLEAQKRTYKLRKEQLKEEL 598
Query: 358 QDLLSQDWRVKGALL 372
Q+ S R K L
Sbjct: 599 QENPSTPKREKAEWL 613
>gi|48255883 troponin T type 2, cardiac isoform 4 [Homo sapiens]
Length = 282
Score = 45.8 bits (107), Expect = 6e-05
Identities = 40/160 (25%), Positives = 72/160 (45%), Gaps = 20/160 (12%)
Query: 155 LLPDYEDEEEEEEEE------EGDGERKRGDASKPLSDAQGKEHSVSSSREVTSSVLPND 208
++ +YE+EE+EE+EE E + E + A + + + KE E S P
Sbjct: 7 VVEEYEEEEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEE--SKPKPRS 64
Query: 209 FFSTNPPKAPIIPHSGSIEKAEIHEKVVERRENTAEALPEGFFDDPEVDA--------RV 260
F P P IP ++ +IH K +E+ N +AL E F++ + + R+
Sbjct: 65 FMPNLVP--PKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRI 122
Query: 261 RKVDAPKDQMDKEWDEFQKAMRQVNTISEAIVAEEDEEGR 300
+ A + + + +E +K + N ++E E+EE R
Sbjct: 123 ERRRAERAEQQRIRNEREK--ERQNRLAEERARREEEENR 160
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 45.8 bits (107), Expect = 6e-05
Identities = 53/201 (26%), Positives = 88/201 (43%), Gaps = 15/201 (7%)
Query: 162 EEEEEEEEEGDGERKRGDASKPLSDAQGKEHSVSSSREVTSSVLPNDFFSTNPPKAPIIP 221
+E++E+EEE + + KRG + + +E + S E L N S+ PK
Sbjct: 185 KEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEER 244
Query: 222 HSGSIEKAEIHEKVVERRENTAEALPEGFFDDPEVDARVR-KVDAPKDQMDK----EWDE 276
GS E + HEK+ E + AEA E + R R K + K D+ E +E
Sbjct: 245 EQGSDEISH-HEKMEEEDKERAEAERARL----EAEERERIKAEQDKKIADERARIEAEE 299
Query: 277 FQKAMRQVNTISEAIVAEEDEEGRLDRQIGEIDEQIECYRRVEKLRNRQDEIKNKLKEIL 336
A + +E +EE R + I E+ + R E+ + ++E K +E
Sbjct: 300 KAAAQERERREAEERERMREEEKRAAEERQRIKEEEK--RAAEERQRIKEEEKRAAEERQ 357
Query: 337 TIKELQKK---EEENADSDDE 354
IKE +K+ E + A +++E
Sbjct: 358 RIKEEEKRAAEERQRARAEEE 378
Score = 43.5 bits (101), Expect = 3e-04
Identities = 55/226 (24%), Positives = 96/226 (42%), Gaps = 33/226 (14%)
Query: 160 EDEEEEEEEEEGDGERKRGDASKPLSDAQGKEHSVSSSREVTSSVLPNDFFSTNPPKAPI 219
ED+E+EEEEEE + KRG + + +E + S E L N S+ PK
Sbjct: 186 EDKEKEEEEEE---KPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEE 242
Query: 220 IPHSGSIEKAEIHEKVVERRENTAEALP-----------EGFFDDPEVDARVR----KVD 264
GS E + HEK+ E + AEA + D D R R +
Sbjct: 243 EREQGSDEISH-HEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKA 301
Query: 265 APKDQMDKEWDEFQKAMRQVNTISEAIVAEEDEEGRLDRQIGEIDEQ----IECYRRVEK 320
A +++ +E +E ++ + +E ++EE R + I E+ E +R+++
Sbjct: 302 AAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKE 361
Query: 321 LRNR----------QDEIKNKLKEILTIKELQKKEEENADSDDEGE 356
R ++E K K++E K+L++K+ ++ +GE
Sbjct: 362 EEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGE 407
Score = 36.2 bits (82), Expect = 0.049
Identities = 50/221 (22%), Positives = 95/221 (42%), Gaps = 32/221 (14%)
Query: 163 EEEEEEEEGDGERKRGDASKPLSDAQGKEHSVSSSR---EVTSSVLPNDFFSTNPPKAPI 219
EE + + E+ + + K + K+H++ ++ E + + N KA
Sbjct: 368 EERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKW--VNEKKAQE 425
Query: 220 IPHSGSIEKAEIHEK---VVERRENTAEALPEGFFDDPEV-DARVRKVDAPKDQMDKEWD 275
++ K + EK V +RE E P F E+ D +++K PK+++ K +
Sbjct: 426 DKLQTAVLKKQGEEKGTKVQAKREKLQEDKPT--FKKEEIKDEKIKKDKEPKEEV-KSFM 482
Query: 276 EFQKAMRQVNTIS-----------EAIVAEEDEEGRLDRQIGEIDEQIECYRRVEKLRNR 324
+ +K +V + + E + +D + E Q+E +R+E+LR R
Sbjct: 483 DRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRR 542
Query: 325 QDEIKN----KLKE-----ILTIKELQKKEEENADSDDEGE 356
+ E ++ KLK+ L ++EL+KK EE +E E
Sbjct: 543 RGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEE 583
Score = 32.7 bits (73), Expect = 0.54
Identities = 73/366 (19%), Positives = 146/366 (39%), Gaps = 49/366 (13%)
Query: 2 ASSASARTPAGKRVINQEELRRLMKEKQRLSTSRKRIESPFAKYNRLGQLSCALCNTPVK 61
A+ R A +R +EE +R +E+QR+ KR + +K
Sbjct: 302 AAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQR---------------IK 346
Query: 62 SELLWQTHVLGKQHREKVAELKGAKEASQGSSASSAPHSVKRKAPDADDQDVKRA-KATL 120
E + ++ R K E + A+E + + V+ + + ++ K A + T
Sbjct: 347 EE---EKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETK 403
Query: 121 V--PQVQPSTSAWTTNFDKIGKEFIRATPSKPSGLSLLPDYEDEEEEEEEEEGDGERKRG 178
+ +V+ N K ++ ++ K G + + E+ +E++ +++
Sbjct: 404 IKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEI 463
Query: 179 DASKPLSDAQGKEHSVS---SSREVTSSVLPNDFFSTNPPKAPIIPHSGSIEKAEIHEKV 235
K D + KE S + T N F T+ K S +A + K
Sbjct: 464 KDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKE 523
Query: 236 VERRENTAEALPEGFFDDPEVDARVRKVDAPKDQMDKEWDEFQKAMRQVNTISEAIVAEE 295
E P+V+A R + + + + E +EF+K ++ A+ EE
Sbjct: 524 AE--------------GAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQ--EAALELEE 567
Query: 296 DEEGRLDRQIGEIDEQIECYRRVEKL--RNRQDEIKNKLKEILTIK-----ELQKKEEEN 348
++ R +R+ ++ E+ E R+ E+ + R++E K +LKE + + E ++K E+
Sbjct: 568 LKKKREERR--KVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPED 625
Query: 349 ADSDDE 354
SDD+
Sbjct: 626 GLSDDK 631
>gi|4826870 nucleobindin 2 [Homo sapiens]
Length = 420
Score = 45.4 bits (106), Expect = 8e-05
Identities = 54/209 (25%), Positives = 91/209 (43%), Gaps = 26/209 (12%)
Query: 161 DEEEEEEEEEGDGERKRGDASKPLSDAQGKEHSVSSSREVTSSVLPNDFFSTNPPKAPII 220
+EE+ +EEE E K+ + P + G + + E T + PNDF K +
Sbjct: 196 NEEKRKEEESKFEEMKKKHENHPKVNHPGSKDQLKEVWEETDGLDPNDFDPKTFFKLHDV 255
Query: 221 PHSGSIEKAEIHEKVVERRENTAEALPEGFFDD----PEVDARVR-----KVDAPKDQMD 271
G +++ E+ + E + P+ DD E R+R +VD KD++
Sbjct: 256 NSDGFLDEQELEALFTKELEKVYD--PKNEEDDMVEMEEERLRMREHVMNEVDTNKDRL- 312
Query: 272 KEWDEFQKAMRQVNTISEAIVAEEDEEGRLDRQIGEIDEQIECYRRVEKLRNRQDEIKNK 331
+EF KA + + E D LD+Q +E+++ Y + L +++E+K K
Sbjct: 313 VTLEEFLKATEKKEFL------EPDSWETLDQQQFFTEEELKEYENIIAL--QENELKKK 364
Query: 332 LKEILTIKELQKKEEENADSDDEGELQDL 360
ELQK++EE D+ E Q L
Sbjct: 365 ------ADELQKQKEELQRQHDQLEAQKL 387
>gi|92859701 myosin VI [Homo sapiens]
Length = 1285
Score = 44.3 bits (103), Expect = 2e-04
Identities = 27/101 (26%), Positives = 54/101 (53%), Gaps = 1/101 (0%)
Query: 258 ARVRKVDAPKDQMDKEWDEFQKAMRQVNTISEAIVAEEDEEGRLDRQIGEIDEQIECYRR 317
A+++ ++Q+ KE+D K+ ++ + + +E+E RL R+I E E+ R
Sbjct: 883 AKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQQEEEAERL-RRIQEEMEKERKRRE 941
Query: 318 VEKLRNRQDEIKNKLKEILTIKELQKKEEENADSDDEGELQ 358
++ R R++E + ++K + K Q++EE DDE +Q
Sbjct: 942 EDEKRRRKEEEERRMKLEMEAKRKQEEEERKKREDDEKRIQ 982
Score = 28.9 bits (63), Expect = 7.8
Identities = 26/148 (17%), Positives = 62/148 (41%), Gaps = 9/148 (6%)
Query: 221 PHSGSIEKAEIHEKVVERRENTAEALPEGFFDDPEVDARVRKVDAPKDQMDKEWDEFQKA 280
P + K +K +++ L +G PE++ +++ ++ D + +
Sbjct: 835 PRIDGLVKVGTLKKRLDKFNEVVSVLKDG---KPEMNKQIKNLEISIDTLMAKIKSTMMT 891
Query: 281 MRQVNTISEAIVAEEDEEGRLDRQIGEIDEQIECYRRVEKLRNRQDEIKNKLKEILTIKE 340
Q+ +A+V +E + + ++ + E+LR Q+E++ + K ++
Sbjct: 892 QEQIQKEYDALVKSSEE------LLSALQKKKQQEEEAERLRRIQEEMEKERKRREEDEK 945
Query: 341 LQKKEEENADSDDEGELQDLLSQDWRVK 368
++KEEE E E + ++ R K
Sbjct: 946 RRRKEEEERRMKLEMEAKRKQEEEERKK 973
>gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens]
Length = 755
Score = 43.9 bits (102), Expect = 2e-04
Identities = 51/224 (22%), Positives = 94/224 (41%), Gaps = 31/224 (13%)
Query: 160 EDEEEEEEEEEGDGERKRGDASKPLSD--AQGKEHSVSSSREVTSSVLPNDFFSTNPPKA 217
+D +E EEE G + D S+ SD K+ S RE + L D
Sbjct: 523 DDLNKESEEEVGPTKESEEDDSEKESDEDCSEKQSEDGSEREFEENGLEKD--------- 573
Query: 218 PIIPHSGSIEKAEIHEKVVERRENTAEALPEGFFDDP-----EVDARVRKVDAPKDQMDK 272
+ GS + E+HE V+++ ++ F DD + + R+ D D+ ++
Sbjct: 574 --LDEEGS--EKELHENVLDKELEENDSENSEFEDDGSEKVLDEEGSEREFDEDSDEKEE 629
Query: 273 EWDEFQKAMRQVNTISEAIVAEEDEEGRLDRQIGEIDEQIECYRRVEKLRNRQDEIKNKL 332
E D ++K + +EDEE ++ + D++ E EKL D+ +++
Sbjct: 630 EEDTYEKVFDDESD------EKEDEEYADEKGLEAADKKAEEGDADEKLFEESDDKEDED 683
Query: 333 KEILTIKELQKKEEENADS-----DDEGELQDLLSQDWRVKGAL 371
+ +++ +K E+ DS D+E + + L D +G L
Sbjct: 684 ADGKEVEDADEKLFEDDDSNEKLFDEEEDSSEKLFDDSDERGTL 727
Score = 30.0 bits (66), Expect = 3.5
Identities = 67/294 (22%), Positives = 104/294 (35%), Gaps = 61/294 (20%)
Query: 76 REKVAELKG------AKEASQGSSASSAPHSVKRKAPDADDQDVKRAKATLVPQVQPSTS 129
RE+ L+G A EA++G S + + +R P RA+ PSTS
Sbjct: 360 REREERLRGWEAFLNAPEANRGLRRSDSVSASERAGPS-------RARHF---SEHPSTS 409
Query: 130 AWTTNFDKIGKEFIRATPSKPSGLSLLPDYEDEEEEEEEEEGDGERKRGDASKPLSDAQG 189
G F K +E E+ E EEG E ++S +G
Sbjct: 410 KMNAQETATGMAFEEPIDEKK--------FEKTEDGGEFEEGASENNAKESSPEKEAEEG 461
Query: 190 KEHSVSSS----REVTSSVLPNDFFSTNPPKAPIIPHSGSIEKAEIHEKVVERRENTAEA 245
S R S + NP + GS E + E + +N E
Sbjct: 462 CPEKESEEGCPKRGFEGSCSQKESEEGNPVR-------GSEEDSPKKESKKKTLKNDCEE 514
Query: 246 LPEGFFDDPEVDARVRKVDAPKDQMDKEWDEFQKAMRQVNTISEAIVAEEDEEGRLDRQI 305
G + E D ++KE +E +V E+ E+D E D
Sbjct: 515 --NGLAKESE------------DDLNKESEE------EVGPTKES--EEDDSEKESDEDC 552
Query: 306 GEIDEQIECYRRVEK--LRNRQDE--IKNKLKEILTIKELQKKEEENADSDDEG 355
E + R E+ L DE + +L E + KEL++ + EN++ +D+G
Sbjct: 553 SEKQSEDGSEREFEENGLEKDLDEEGSEKELHENVLDKELEENDSENSEFEDDG 606
>gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens]
Length = 755
Score = 43.9 bits (102), Expect = 2e-04
Identities = 51/224 (22%), Positives = 94/224 (41%), Gaps = 31/224 (13%)
Query: 160 EDEEEEEEEEEGDGERKRGDASKPLSD--AQGKEHSVSSSREVTSSVLPNDFFSTNPPKA 217
+D +E EEE G + D S+ SD K+ S RE + L D
Sbjct: 523 DDLNKESEEEVGPTKESEEDDSEKESDEDCSEKQSEDGSEREFEENGLEKD--------- 573
Query: 218 PIIPHSGSIEKAEIHEKVVERRENTAEALPEGFFDDP-----EVDARVRKVDAPKDQMDK 272
+ GS + E+HE V+++ ++ F DD + + R+ D D+ ++
Sbjct: 574 --LDEEGS--EKELHENVLDKELEENDSENSEFEDDGSEKVLDEEGSEREFDEDSDEKEE 629
Query: 273 EWDEFQKAMRQVNTISEAIVAEEDEEGRLDRQIGEIDEQIECYRRVEKLRNRQDEIKNKL 332
E D ++K + +EDEE ++ + D++ E EKL D+ +++
Sbjct: 630 EEDTYEKVFDDESD------EKEDEEYADEKGLEAADKKAEEGDADEKLFEESDDKEDED 683
Query: 333 KEILTIKELQKKEEENADS-----DDEGELQDLLSQDWRVKGAL 371
+ +++ +K E+ DS D+E + + L D +G L
Sbjct: 684 ADGKEVEDADEKLFEDDDSNEKLFDEEEDSSEKLFDDSDERGTL 727
Score = 30.0 bits (66), Expect = 3.5
Identities = 67/294 (22%), Positives = 104/294 (35%), Gaps = 61/294 (20%)
Query: 76 REKVAELKG------AKEASQGSSASSAPHSVKRKAPDADDQDVKRAKATLVPQVQPSTS 129
RE+ L+G A EA++G S + + +R P RA+ PSTS
Sbjct: 360 REREERLRGWEAFLNAPEANRGLRRSDSVSASERAGPS-------RARHF---SEHPSTS 409
Query: 130 AWTTNFDKIGKEFIRATPSKPSGLSLLPDYEDEEEEEEEEEGDGERKRGDASKPLSDAQG 189
G F K +E E+ E EEG E ++S +G
Sbjct: 410 KMNAQETATGMAFEEPIDEKK--------FEKTEDGGEFEEGASENNAKESSPEKEAEEG 461
Query: 190 KEHSVSSS----REVTSSVLPNDFFSTNPPKAPIIPHSGSIEKAEIHEKVVERRENTAEA 245
S R S + NP + GS E + E + +N E
Sbjct: 462 CPEKESEEGCPKRGFEGSCSQKESEEGNPVR-------GSEEDSPKKESKKKTLKNDCEE 514
Query: 246 LPEGFFDDPEVDARVRKVDAPKDQMDKEWDEFQKAMRQVNTISEAIVAEEDEEGRLDRQI 305
G + E D ++KE +E +V E+ E+D E D
Sbjct: 515 --NGLAKESE------------DDLNKESEE------EVGPTKES--EEDDSEKESDEDC 552
Query: 306 GEIDEQIECYRRVEK--LRNRQDE--IKNKLKEILTIKELQKKEEENADSDDEG 355
E + R E+ L DE + +L E + KEL++ + EN++ +D+G
Sbjct: 553 SEKQSEDGSEREFEENGLEKDLDEEGSEKELHENVLDKELEENDSENSEFEDDG 606
>gi|195976782 Paf1/RNA polymerase II complex component [Homo
sapiens]
Length = 710
Score = 43.9 bits (102), Expect = 2e-04
Identities = 53/266 (19%), Positives = 110/266 (41%), Gaps = 29/266 (10%)
Query: 102 KRKAPDADDQD--VKRAKATLVPQVQPSTSAWTTNFDK---------IGKEFIRATPSKP 150
KRK D+++++ V + A+ + S WT +K I K+ +
Sbjct: 73 KRKRSDSEEKEPPVSQPAASSDSETSDSDDEWTFGSNKNKKKGKARKIEKKGTMKKQANK 132
Query: 151 SGLSLLPDYEDEEEEEEEEEGDGERKRGDASKPLSDAQGKEHSVSSSREVTSSVLPNDFF 210
+ S D + E EEG+ ++S SD+ SS E D
Sbjct: 133 TASSGSSDKDSSAESSAPEEGEVSDSDSNSSSSSSDSDS-----SSEDEEFHDGYGEDLM 187
Query: 211 STNPPKAPIIPHSGSIEKAEIHEKVVERRENTAEALPEGFFDDPEVDARVRKVDAPKDQM 270
+A + + + E+ ++ +R E L F E+ +++ + +
Sbjct: 188 GDEEDRARLEQMTEKEREQELFNRIEKR-----EVLKRRF----EIKKKLKTAKKKEKKE 238
Query: 271 DKEWDEFQKAMRQVNTISEAIVAEEDEEGRLDRQIGEIDEQIECYRRVEKLRNRQDEIKN 330
K+ E ++ +++ I E+ V ++E R R ++D++ + +E+L+ +++ KN
Sbjct: 239 KKKKQEEEQEKKKLTQIQESQVTSHNKERRSKRD-EKLDKKSQA---MEELKAEREKRKN 294
Query: 331 KLKEILTIKELQKKEEENADSDDEGE 356
+ E+L K+ K E +D ++E E
Sbjct: 295 RTAELLAKKQPLKTSEVYSDDEEEEE 320
Score = 30.4 bits (67), Expect = 2.7
Identities = 73/391 (18%), Positives = 157/391 (40%), Gaps = 71/391 (18%)
Query: 12 GKRVINQEELRRLMKEKQRLSTSRKRIESPFAKYNRLGQLSCALCNTPVKSELLWQTHVL 71
G+ ++ EE R +++ T ++R + F NR+ + +K +L
Sbjct: 183 GEDLMGDEEDRARLEQM----TEKEREQELF---NRIEKREVLKRRFEIKKKLKTAKKKE 235
Query: 72 GKQHREKVAELKGAKEASQGSSASSAPHSVKRKAPDADDQDVKRAKATLVPQVQPSTSAW 131
K+ ++K E + K+ +Q + H+ +R++ + D K+++A ++ +
Sbjct: 236 KKEKKKKQEEEQEKKKLTQIQESQVTSHNKERRSKRDEKLD-KKSQA-----MEELKAER 289
Query: 132 TTNFDKIGKEFIRATPSKPSGLSLLPDYEDEEEEEEEEEGDGERKRGDASKPLSDAQGKE 191
++ + + P K S + Y D+EEEEE+++ + R + + + KE
Sbjct: 290 EKRKNRTAELLAKKQPLKTSEV-----YSDDEEEEEDDKSSEKSDRSSRTSSSDEEEEKE 344
Query: 192 HSVSSSREVTSSVLPND------------------FFS---------------TNPPKAP 218
S+ V+ LP + FF+ + P
Sbjct: 345 EIPPKSQPVS---LPEELNRVRLSRHKLERWCHMPFFAKTVTGCFVRIGIGNHNSKPVYR 401
Query: 219 IIPHSGSIEKAEIHEKVVERRENTAEALPEGFFDDPEVDARVRKVDAPKDQ--MDKEWDE 276
+ +G +E A++++ + R N L G D RV +++ +Q + E+ +
Sbjct: 402 VAEITGVVETAKVYQ-LGGTRTNKGLQLRHG------NDQRVFRLEFVSNQEFTESEFMK 454
Query: 277 FQKAM----RQVNTISEAIVAEEDEEGRLDRQIGEIDEQIECYRRVEKLRNRQDEIKNKL 332
+++AM Q+ T+ E E + L+ + + D + E + E+ R K
Sbjct: 455 WKEAMFSAGMQLPTLDEINKKELSIKEALNYKFNDQDIE-EIVKEKERFRKAPPNYAMKK 513
Query: 333 KEILTIKELQKKEEENADSDDEGELQDLLSQ 363
++L K + E+ D D ++QD L++
Sbjct: 514 TQLLKEKAM---AEDLGDQDKAKQIQDQLNE 541
>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
[Homo sapiens]
Length = 2073
Score = 43.5 bits (101), Expect = 3e-04
Identities = 57/274 (20%), Positives = 104/274 (37%), Gaps = 48/274 (17%)
Query: 86 KEASQGSSASSA---PHSVKRKAPDADDQDVKRAKATLVPQVQPSTSAWTTNFDKIGKEF 142
KE S+G ++ S VK Q+ R + T P V P+TS D + K
Sbjct: 1293 KETSEGKTSPSPIRIEEEVKETGEALLPQEENRREETCAP-VSPNTSPGEKPEDDLIK-- 1349
Query: 143 IRATPSKPSGLSLLPDYEDEEEEEEEEEGDGERKRGDASKPLSDAQGKEH---SVSSSRE 199
P + + E+EEEEEEEEEG+ E G+ K A+ +E +S+ +E
Sbjct: 1350 ----PEEEE-----EEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKE 1400
Query: 200 VTSSVLPNDFFSTNPPKAPIIPHSGSIEKAEIHEKVVERRENTAEALPEGFFDDPEVDAR 259
+ A + + E E+ + E D E D+
Sbjct: 1401 ---------------------------DSARLDDHEEEEEEDEEPSHNEDHDADDEDDSH 1433
Query: 260 VRKVDAPKDQMDKEWDEFQKAMRQVNTISEAIVAEEDEEGRLDRQIGEIDEQIECYRRVE 319
+ + K+++ +E F++ + T + V + G +D C +
Sbjct: 1434 MESAEVEKEELPRE--SFKEVLENQETFLDLNVQPGHSNPEVLMDCG-VDLTASCNSEPK 1490
Query: 320 KLRNRQDEIKNKLKEILTIKELQKKEEENADSDD 353
+L + + +E ++ QK++++N+ D
Sbjct: 1491 ELAGDPEAVPESDEEPPPGEQAQKQDQKNSKEVD 1524
Score = 35.8 bits (81), Expect = 0.064
Identities = 35/176 (19%), Positives = 78/176 (44%), Gaps = 15/176 (8%)
Query: 160 EDEEEEEEEEEGDGERKRGDASKPLSDAQGKEHSVSSSREVTSSVLPNDFFSTNPPKAPI 219
E+EEE+EEEEE + E + + + + + +E ++ SS + + + +
Sbjct: 1072 EEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSS---PPRLTKPQSVAIKRKRPFV 1128
Query: 220 IPHSGSIEKAEIHEKV-VERRENTAEALPEGFFDDPEVDARVRKVDAPKDQMDKEWDEFQ 278
+ ++ I+ V E T E L E FD+ + + + +++ P +++ E D +
Sbjct: 1129 LKKKRGRKRRRINSSVTTETISETTEVLNEP-FDNSDEERPMPQLE-PTCEIEVEEDGRK 1186
Query: 279 KAMRQVNTISEAIVAEEDEEGRLDRQIGEIDEQIECYRRVEKLRNRQDEIKNKLKE 334
+R+ A + + G+ + E + C++ + RN ++ + LKE
Sbjct: 1187 PVLRK---------AFQHQPGKKRQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKE 1233
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 43.1 bits (100), Expect = 4e-04
Identities = 53/201 (26%), Positives = 86/201 (42%), Gaps = 29/201 (14%)
Query: 160 EDEEEEEEEEEGDG--------ERKRGDASKPLSDAQGKEHSVSSSREVTSSVLPNDFFS 211
E+EEEEEEEEE +G E + + + + + +E S S+ EV+ + D
Sbjct: 280 EEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEER 339
Query: 212 TNPPKAPIIPHS----GSIEKAEIHEKVVERRENTAEALPEGFF--DDPEVDARVRKVDA 265
N ++P S S E E E+V E ++ AL EG + D P + K +
Sbjct: 340 ENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSS-ALTEGDYVPDSPALSPIELKQEL 398
Query: 266 PKD----QMDKEWDEFQKAMRQVNTISEAIVAEEDEEGRLDRQIGEIDEQIECYRRVEKL 321
PK Q + +EFQ R EE G + R + ++I +R++
Sbjct: 399 PKYLPALQGCRSVEEFQCLNR----------IEEGTYGVVYRAKDKKTDEIVALKRLKME 448
Query: 322 RNRQDEIKNKLKEILTIKELQ 342
+ ++ L+EI TI + Q
Sbjct: 449 KEKEGFPITSLREINTILKAQ 469
Score = 28.9 bits (63), Expect = 7.8
Identities = 33/146 (22%), Positives = 64/146 (43%), Gaps = 18/146 (12%)
Query: 225 SIEKAEIHEKVVE--------RRENTAEALPEGFFDD------PEVDARVRKVDAPKDQM 270
S+E+ E+ + +E RRE++ E G DD P+ +R KV KD+
Sbjct: 47 SLEEGELRDHCMEITIRNSPYRREDSME--DRGEEDDSLAIKPPQQMSRKEKVHHRKDEK 104
Query: 271 DKEWDEFQKAMRQVNTISEAIVAEEDEEGRLDRQIGEIDEQIECYRRVEKLRNRQDEIKN 330
KE + ++ EE ++ R + + + E + R E R+R ++++
Sbjct: 105 RKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRE--RDRLEQLER 162
Query: 331 KLKEILTIKELQKKEEENADSDDEGE 356
K + ++E QK++ E + + E
Sbjct: 163 KRERERKMREQQKEQREQKERERRAE 188
>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
8 [Homo sapiens]
Length = 780
Score = 43.1 bits (100), Expect = 4e-04
Identities = 53/201 (26%), Positives = 86/201 (42%), Gaps = 29/201 (14%)
Query: 160 EDEEEEEEEEEGDG--------ERKRGDASKPLSDAQGKEHSVSSSREVTSSVLPNDFFS 211
E+EEEEEEEEE +G E + + + + + +E S S+ EV+ + D
Sbjct: 289 EEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEER 348
Query: 212 TNPPKAPIIPHS----GSIEKAEIHEKVVERRENTAEALPEGFF--DDPEVDARVRKVDA 265
N ++P S S E E E+V E ++ AL EG + D P + K +
Sbjct: 349 ENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSS-ALTEGDYVPDSPALSPIELKQEL 407
Query: 266 PKD----QMDKEWDEFQKAMRQVNTISEAIVAEEDEEGRLDRQIGEIDEQIECYRRVEKL 321
PK Q + +EFQ R EE G + R + ++I +R++
Sbjct: 408 PKYLPALQGCRSVEEFQCLNR----------IEEGTYGVVYRAKDKKTDEIVALKRLKME 457
Query: 322 RNRQDEIKNKLKEILTIKELQ 342
+ ++ L+EI TI + Q
Sbjct: 458 KEKEGFPITSLREINTILKAQ 478
>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
5 [Homo sapiens]
Length = 748
Score = 43.1 bits (100), Expect = 4e-04
Identities = 53/201 (26%), Positives = 86/201 (42%), Gaps = 29/201 (14%)
Query: 160 EDEEEEEEEEEGDG--------ERKRGDASKPLSDAQGKEHSVSSSREVTSSVLPNDFFS 211
E+EEEEEEEEE +G E + + + + + +E S S+ EV+ + D
Sbjct: 257 EEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEER 316
Query: 212 TNPPKAPIIPHS----GSIEKAEIHEKVVERRENTAEALPEGFF--DDPEVDARVRKVDA 265
N ++P S S E E E+V E ++ AL EG + D P + K +
Sbjct: 317 ENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSS-ALTEGDYVPDSPALSPIELKQEL 375
Query: 266 PKD----QMDKEWDEFQKAMRQVNTISEAIVAEEDEEGRLDRQIGEIDEQIECYRRVEKL 321
PK Q + +EFQ R EE G + R + ++I +R++
Sbjct: 376 PKYLPALQGCRSVEEFQCLNR----------IEEGTYGVVYRAKDKKTDEIVALKRLKME 425
Query: 322 RNRQDEIKNKLKEILTIKELQ 342
+ ++ L+EI TI + Q
Sbjct: 426 KEKEGFPITSLREINTILKAQ 446
>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
4 [Homo sapiens]
Length = 737
Score = 43.1 bits (100), Expect = 4e-04
Identities = 53/201 (26%), Positives = 86/201 (42%), Gaps = 29/201 (14%)
Query: 160 EDEEEEEEEEEGDG--------ERKRGDASKPLSDAQGKEHSVSSSREVTSSVLPNDFFS 211
E+EEEEEEEEE +G E + + + + + +E S S+ EV+ + D
Sbjct: 246 EEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEER 305
Query: 212 TNPPKAPIIPHS----GSIEKAEIHEKVVERRENTAEALPEGFF--DDPEVDARVRKVDA 265
N ++P S S E E E+V E ++ AL EG + D P + K +
Sbjct: 306 ENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSS-ALTEGDYVPDSPALSPIELKQEL 364
Query: 266 PKD----QMDKEWDEFQKAMRQVNTISEAIVAEEDEEGRLDRQIGEIDEQIECYRRVEKL 321
PK Q + +EFQ R EE G + R + ++I +R++
Sbjct: 365 PKYLPALQGCRSVEEFQCLNR----------IEEGTYGVVYRAKDKKTDEIVALKRLKME 414
Query: 322 RNRQDEIKNKLKEILTIKELQ 342
+ ++ L+EI TI + Q
Sbjct: 415 KEKEGFPITSLREINTILKAQ 435
>gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isoform
3 [Homo sapiens]
Length = 526
Score = 43.1 bits (100), Expect = 4e-04
Identities = 53/201 (26%), Positives = 86/201 (42%), Gaps = 29/201 (14%)
Query: 160 EDEEEEEEEEEGDG--------ERKRGDASKPLSDAQGKEHSVSSSREVTSSVLPNDFFS 211
E+EEEEEEEEE +G E + + + + + +E S S+ EV+ + D
Sbjct: 35 EEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEER 94
Query: 212 TNPPKAPIIPHS----GSIEKAEIHEKVVERRENTAEALPEGFF--DDPEVDARVRKVDA 265
N ++P S S E E E+V E ++ AL EG + D P + K +
Sbjct: 95 ENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSS-ALTEGDYVPDSPALSPIELKQEL 153
Query: 266 PKD----QMDKEWDEFQKAMRQVNTISEAIVAEEDEEGRLDRQIGEIDEQIECYRRVEKL 321
PK Q + +EFQ R EE G + R + ++I +R++
Sbjct: 154 PKYLPALQGCRSVEEFQCLNR----------IEEGTYGVVYRAKDKKTDEIVALKRLKME 203
Query: 322 RNRQDEIKNKLKEILTIKELQ 342
+ ++ L+EI TI + Q
Sbjct: 204 KEKEGFPITSLREINTILKAQ 224
>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
2 [Homo sapiens]
Length = 782
Score = 43.1 bits (100), Expect = 4e-04
Identities = 53/201 (26%), Positives = 86/201 (42%), Gaps = 29/201 (14%)
Query: 160 EDEEEEEEEEEGDG--------ERKRGDASKPLSDAQGKEHSVSSSREVTSSVLPNDFFS 211
E+EEEEEEEEE +G E + + + + + +E S S+ EV+ + D
Sbjct: 291 EEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEER 350
Query: 212 TNPPKAPIIPHS----GSIEKAEIHEKVVERRENTAEALPEGFF--DDPEVDARVRKVDA 265
N ++P S S E E E+V E ++ AL EG + D P + K +
Sbjct: 351 ENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSS-ALTEGDYVPDSPALSPIELKQEL 409
Query: 266 PKD----QMDKEWDEFQKAMRQVNTISEAIVAEEDEEGRLDRQIGEIDEQIECYRRVEKL 321
PK Q + +EFQ R EE G + R + ++I +R++
Sbjct: 410 PKYLPALQGCRSVEEFQCLNR----------IEEGTYGVVYRAKDKKTDEIVALKRLKME 459
Query: 322 RNRQDEIKNKLKEILTIKELQ 342
+ ++ L+EI TI + Q
Sbjct: 460 KEKEGFPITSLREINTILKAQ 480
>gi|116174778 centrosome spindle pole associated protein 1 isoform b
[Homo sapiens]
Length = 1221
Score = 42.7 bits (99), Expect = 5e-04
Identities = 47/209 (22%), Positives = 88/209 (42%), Gaps = 18/209 (8%)
Query: 160 EDEEEEEEEEEGDGERK------RGDASKPLSDAQGKEHS-VSSSREVTSSVLPNDFFST 212
E EE+EE E + + E + +G PL DA+G + ++ N T
Sbjct: 615 EREEKEEYEAKLEAEMRTYNPWGKGGGGAPLRDAKGNLITDLNRMHRQNIDAYHNPDART 674
Query: 213 NPPKAPIIPHSGSI--EKAEIHEKVVERRENTAEALPEGF-----FDDPEVDARVRKVDA 265
K ++ ++ AE E + + F F +P + ++++ +
Sbjct: 675 YEDKRAVVSLDPNLATSNAENLEDAANKSSGHMQTQSSPFARGNVFGEPPTELQIKQQEL 734
Query: 266 PKDQMDKEWDEFQKAMRQVNTISEAIVAEEDEEGRLDRQIGEIDEQIECYRRVEKLRNRQ 325
K+ + + +E K R+ +AEE EE RL Q I ++ E EK R ++
Sbjct: 735 YKNFLRFQIEE--KKQREEAERERLRIAEEKEERRLAEQRARIQQEYE--EEQEKKREKE 790
Query: 326 DEIKNKLKEILTIKELQKKEEENADSDDE 354
+E + K +E + + E ++KE E ++E
Sbjct: 791 EEQRLKNEEHIRLAEERQKEAERKKKEEE 819
>gi|116174789 centrosome spindle pole associated protein 1 isoform a
[Homo sapiens]
Length = 1256
Score = 42.7 bits (99), Expect = 5e-04
Identities = 47/209 (22%), Positives = 88/209 (42%), Gaps = 18/209 (8%)
Query: 160 EDEEEEEEEEEGDGERK------RGDASKPLSDAQGKEHS-VSSSREVTSSVLPNDFFST 212
E EE+EE E + + E + +G PL DA+G + ++ N T
Sbjct: 650 EREEKEEYEAKLEAEMRTYNPWGKGGGGAPLRDAKGNLITDLNRMHRQNIDAYHNPDART 709
Query: 213 NPPKAPIIPHSGSI--EKAEIHEKVVERRENTAEALPEGF-----FDDPEVDARVRKVDA 265
K ++ ++ AE E + + F F +P + ++++ +
Sbjct: 710 YEDKRAVVSLDPNLATSNAENLEDAANKSSGHMQTQSSPFARGNVFGEPPTELQIKQQEL 769
Query: 266 PKDQMDKEWDEFQKAMRQVNTISEAIVAEEDEEGRLDRQIGEIDEQIECYRRVEKLRNRQ 325
K+ + + +E K R+ +AEE EE RL Q I ++ E EK R ++
Sbjct: 770 YKNFLRFQIEE--KKQREEAERERLRIAEEKEERRLAEQRARIQQEYE--EEQEKKREKE 825
Query: 326 DEIKNKLKEILTIKELQKKEEENADSDDE 354
+E + K +E + + E ++KE E ++E
Sbjct: 826 EEQRLKNEEHIRLAEERQKEAERKKKEEE 854
>gi|48255879 troponin T type 2, cardiac isoform 2 [Homo sapiens]
Length = 288
Score = 42.4 bits (98), Expect = 7e-04
Identities = 55/246 (22%), Positives = 103/246 (41%), Gaps = 48/246 (19%)
Query: 155 LLPDYEDEEEE-----------EEEEEGDGERKRGDASKPLSDAQGKEHSVSSSREVTSS 203
++ +YE+EE+E EE+ E + E + A + + + KE E S
Sbjct: 7 VVEEYEEEEQEEAAVEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEE--SK 64
Query: 204 VLPNDFFSTNPPKAPIIPHSGSIEKAEIHEKVVERRENTAEALPEGFFDDPEVDA----- 258
P F P P IP ++ +IH K +E+ N +AL E F++ + +
Sbjct: 65 PKPRSFMPNLVP--PKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVS 122
Query: 259 ---RVRKVDAPKDQMDKEWDEFQKAMRQVNTISEAIVAEEDEEGRLDRQI---------- 305
R+ + A + + + +E +K + N ++E E+EE R +
Sbjct: 123 LKDRIERRRAERAEQQRIRNEREK--ERQNRLAEERARREEEENRRKAEDEARKKKALSN 180
Query: 306 -----GEIDEQIECYRRVEKLRNRQDEIKNKLKEILTIKELQKKEEENADSDDEGELQDL 360
G I +Q + R+ K RQ E + K K+IL ++++ D +E +L++
Sbjct: 181 MMHFGGYIQKQAQTERKSGK---RQTE-REKKKKILA----ERRKVLAIDHLNEDQLREK 232
Query: 361 LSQDWR 366
+ W+
Sbjct: 233 AKELWQ 238
>gi|48255877 troponin T type 2, cardiac isoform 1 [Homo sapiens]
Length = 295
Score = 42.4 bits (98), Expect = 7e-04
Identities = 50/229 (21%), Positives = 100/229 (43%), Gaps = 34/229 (14%)
Query: 160 EDEEEEEE------EEEGDGERKRGDASKPLSDA-QGKEHSVSSSREVTSSVLPNDFFST 212
EDE+E+EE E E + E R + + +A + ++ + S+ S +PN
Sbjct: 29 EDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFMPN----L 84
Query: 213 NPPKAPIIPHSGSIEKAEIHEKVVERRENTAEALPEGFFDDPEVDA--------RVRKVD 264
PPK IP ++ +IH K +E+ N +AL E F++ + + R+ +
Sbjct: 85 VPPK---IPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIERRR 141
Query: 265 APKDQMDKEWDEFQKAMRQVNTISEAIVAEEDE-------EGRLDRQIGEIDEQIECYRR 317
A + + + +E +K RQ E EE+E E R + + + ++
Sbjct: 142 AERAEQQRIRNEREKE-RQNRLAEERARREEEENRRKAEDEARKKKALSNMMHFGGYIQK 200
Query: 318 VEKLRNRQDEIKNKLKEILTIKELQKKEEENADSDDEGELQDLLSQDWR 366
E+ ++ + K K+IL ++++ D +E +L++ + W+
Sbjct: 201 TERKSGKRQTEREKKKKILA----ERRKVLAIDHLNEDQLREKAKELWQ 245
>gi|48255881 troponin T type 2, cardiac isoform 3 [Homo sapiens]
Length = 285
Score = 42.0 bits (97), Expect = 9e-04
Identities = 50/238 (21%), Positives = 99/238 (41%), Gaps = 35/238 (14%)
Query: 155 LLPDYEDEEEE-----------EEEEEGDGERKRGDASKPLSDAQGKEHSVSSSREVTSS 203
++ +YE+EE+E EE+ E + E + A + + + KE E S
Sbjct: 7 VVEEYEEEEQEEAAVEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEE--SK 64
Query: 204 VLPNDFFSTNPPKAPIIPHSGSIEKAEIHEKVVERRENTAEALPEGFFDDPEVDA----- 258
P F P P IP ++ +IH K +E+ N +AL E F++ + +
Sbjct: 65 PKPRSFMPNLVP--PKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVS 122
Query: 259 ---RVRKVDAPKDQMDKEWDEFQKAMRQVNTISEAIVAEEDE-------EGRLDRQIGEI 308
R+ + A + + + +E +K RQ E EE+E E R + + +
Sbjct: 123 LKDRIERRRAERAEQQRIRNEREKE-RQNRLAEERARREEEENRRKAEDEARKKKALSNM 181
Query: 309 DEQIECYRRVEKLRNRQDEIKNKLKEILTIKELQKKEEENADSDDEGELQDLLSQDWR 366
++ E+ ++ + K K+IL ++++ D +E +L++ + W+
Sbjct: 182 MHFGGYIQKTERKSGKRQTEREKKKKILA----ERRKVLAIDHLNEDQLREKAKELWQ 235
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 42.0 bits (97), Expect = 9e-04
Identities = 36/159 (22%), Positives = 79/159 (49%), Gaps = 29/159 (18%)
Query: 232 HEKVVERRENTAEALPEGFFDDPEVDARVRKVDAPKDQMDKEWDEFQKAMRQVNTISEAI 291
+E++ ++ E LP + E+ V+++ K ++++ +F Q NT+ E +
Sbjct: 220 NEELKKKNAELQEKLPLAESEKSEIQLNVKEL---KRKLERA--KFLLPQVQTNTLQEEM 274
Query: 292 VAEEDE------------------EGRLDRQIGEIDEQIE-CYRRVEKLRNRQDEIKNKL 332
+E+E E RL Q G++ EQ E +R+ ++LR ++ E++ +
Sbjct: 275 WRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQE 334
Query: 333 KEILTIKELQKKEEENADSDD-----EGELQDLLSQDWR 366
KE+ KEL+++EE+ + ++ E ++++ + WR
Sbjct: 335 KELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWR 373
Score = 33.1 bits (74), Expect = 0.41
Identities = 34/157 (21%), Positives = 70/157 (44%), Gaps = 19/157 (12%)
Query: 227 EKAEIHEKVVERRENTAEALPEGFFDDPEVDARVRKVDAPKDQMDKEWDEFQKAMRQVNT 286
++ E+ E+ E RE E + E + + + ++Q +K W + ++ Q
Sbjct: 326 QEKELREQEKELREQKELREQEEQMQEQE-EKMWEQEEKMREQEEKMWRQEERLWEQEKQ 384
Query: 287 ISEAIVAEEDEEGRL---DRQIGEIDEQI----ECYRRVEKLRNRQD---------EIKN 330
+ E D+E R+ D ++ E +E++ + + +VEK+R + + +
Sbjct: 385 MREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEE 444
Query: 331 KLKEILTIKELQKK--EEENADSDDEGELQDLLSQDW 365
K++E I+E +KK EEE + E ++Q W
Sbjct: 445 KMQEEERIREREKKMREEEETMREQEEKMQKQEENMW 481
Score = 32.3 bits (72), Expect = 0.70
Identities = 26/107 (24%), Positives = 60/107 (56%), Gaps = 14/107 (13%)
Query: 267 KDQMDKEWDEFQKAMRQVNTISEAIVAEEDEEGRLDRQIGEIDEQIE-----CYRRVEKL 321
++Q +K W + +K +R+ E + E+++E R +++ E +EQ++ + + EK+
Sbjct: 310 REQEEKMWRQ-EKRLRE----QEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKM 364
Query: 322 RNRQDEIKNKLKEILTIKELQKKEEENADSDDEGELQDLLSQDWRVK 368
R +++++ + +E L +E Q +E+E D E + + QD R++
Sbjct: 365 REQEEKMWRQ-EERLWEQEKQMREQEQKMRDQE---ERMWEQDERLR 407
Score = 31.2 bits (69), Expect = 1.6
Identities = 21/102 (20%), Positives = 49/102 (48%), Gaps = 3/102 (2%)
Query: 267 KDQMDKEWDEFQKAMRQVNTISEAIVAEED---EEGRLDRQIGEIDEQIECYRRVEKLRN 323
+DQ K WD+ ++ ++ + +E+ EE R+ + ++ E+ E R E+
Sbjct: 554 RDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQ 613
Query: 324 RQDEIKNKLKEILTIKELQKKEEENADSDDEGELQDLLSQDW 365
Q+E + +E + +E + +E+E + E ++ + + W
Sbjct: 614 EQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMW 655
Score = 31.2 bits (69), Expect = 1.6
Identities = 37/214 (17%), Positives = 91/214 (42%), Gaps = 10/214 (4%)
Query: 159 YEDEEEEEEEEEGDGERKRGDASKPLSDAQGKEHSVSSSREVTSSVLPNDFFSTNPPKAP 218
+E EE+ E+EE E++R K K +E + + +
Sbjct: 641 WEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQE 700
Query: 219 IIPHSGSIEKAEIHEKVVERRENTAEALPEGFFDDPEVDARVRKVDAPKDQMDKEWDEFQ 278
+ EK E + ER + E + ++ + K+ +++M W++ +
Sbjct: 701 --KKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEM---WEQEE 755
Query: 279 KAMRQVNTISEAIVAEEDEEGRLDRQIGEIDEQIECYRRVEKLRNRQDEIKNKLKEILTI 338
K Q + E E +E + + ++ EQ + + + EK+R+++++++ + +++
Sbjct: 756 KMWEQEEKMWEQQRLPEQKEKLWEHE--KMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQ 813
Query: 339 KELQKKEEENADSDDE---GELQDLLSQDWRVKG 369
+E + +EE +E G+ + + Q+ ++ G
Sbjct: 814 EEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWG 847
Score = 28.9 bits (63), Expect = 7.8
Identities = 23/91 (25%), Positives = 42/91 (46%), Gaps = 1/91 (1%)
Query: 257 DARVRKVDAPKDQMDKEWDEFQKAMRQVNTISEAIVAEEDEEGRLDRQIGEIDEQIECYR 316
D R ++Q K WD+ +K MR+ + E +EE + Q ++ EQ E +
Sbjct: 562 DQEERMEKKTQEQEKKTWDQEEK-MREEERMREREKKMREEEEMMREQEEKMQEQEEKMQ 620
Query: 317 RVEKLRNRQDEIKNKLKEILTIKELQKKEEE 347
E+ Q+E + +E + +E + E+E
Sbjct: 621 EQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE 651
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 42.0 bits (97), Expect = 9e-04
Identities = 29/140 (20%), Positives = 69/140 (49%), Gaps = 11/140 (7%)
Query: 233 EKVVERRENTAEALPEGFFDDPEVDARVRKVDAPKDQMDKEWDEFQKAMRQVNTISEAIV 292
EK+ E+ E E + + + ++ + K+ +++M W + +K Q E +
Sbjct: 353 EKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEM---WRQEEKIREQEEKRQEKMW 409
Query: 293 AEEDEEGRLDRQIGEIDEQIECYRRVEKLRNRQDEIKNKLKEILTIKELQKKEEENADSD 352
+E + D +I E +E E +R+ EK+R ++ ++++ +++ ++E ++EEE
Sbjct: 410 RQEKKMREQDEKIREQEE--EMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQ 467
Query: 353 DEG------ELQDLLSQDWR 366
+E ++Q+ + WR
Sbjct: 468 EEKIQRQEEKIQEQEEKTWR 487
Score = 37.7 bits (86), Expect = 0.017
Identities = 25/107 (23%), Positives = 57/107 (53%), Gaps = 9/107 (8%)
Query: 267 KDQMDKEWDEFQKAMRQVNTISEAIVAEEDEEGRLDRQIGEIDEQI-----ECYRRVEKL 321
++Q +K W + +K Q I E +ED+ R + +I E +E+I + +R+ EK+
Sbjct: 321 REQEEKMWRQEEKMHEQEEKIRE----QEDKMWRQEEKIREQEEKIREQEEKMWRQEEKI 376
Query: 322 RNRQDEIKNKLKEILTIKELQKKEEENADSDDEGELQDLLSQDWRVK 368
R + ++I+ + +E+ +E +++EE + + + QD +++
Sbjct: 377 REQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIR 423
Score = 35.4 bits (80), Expect = 0.083
Identities = 29/130 (22%), Positives = 64/130 (49%), Gaps = 8/130 (6%)
Query: 233 EKVVERRENTAEALPEGFFDDPEVDARVRKVDAPKDQMDKEWDEFQKAMR----QVNTIS 288
EK+ E+ E E + E D ++R+ + + +++ E ++ M+ ++ +
Sbjct: 395 EKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVE 454
Query: 289 EAIVAEED----EEGRLDRQIGEIDEQIECYRRVEKLRNRQDEIKNKLKEILTIKELQKK 344
E + EE+ +E ++ RQ +I EQ E R EKL ++++I + +++ +E +
Sbjct: 455 EKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWE 514
Query: 345 EEENADSDDE 354
+EE +E
Sbjct: 515 QEEKMQEQEE 524
Score = 34.7 bits (78), Expect = 0.14
Identities = 23/125 (18%), Positives = 67/125 (53%), Gaps = 4/125 (3%)
Query: 230 EIHEKVVERRENTAEALPEGFFDDPEVDARVRKVDAPKDQMDKEWDEFQKAMRQVNTISE 289
E EK+ E+ E + + + ++ + K+ +D+M ++ ++ ++ ++ E
Sbjct: 308 EQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEE 367
Query: 290 AIVAEEDEEGRLDRQIGEIDEQIECYRRVEKLRNRQDEIKNKLKEILTIKELQKKEEENA 349
+ +E++ D +I E +E E +R+ EK+R ++++ + K+ K++++++E+
Sbjct: 368 KMWRQEEKIREQDEKIQEQEE--EMWRQEEKIREQEEKRQEKMWR--QEKKMREQDEKIR 423
Query: 350 DSDDE 354
+ ++E
Sbjct: 424 EQEEE 428
Score = 30.4 bits (67), Expect = 2.7
Identities = 32/131 (24%), Positives = 63/131 (48%), Gaps = 25/131 (19%)
Query: 230 EIHEKVVERRENTAEALPEGFFDDPEVDARVRKVDAPKDQMDKEWDEFQKAMRQVNTISE 289
E+ EK+ E E E + ++ + K+ ++Q +K W + +K ++Q I E
Sbjct: 452 EVEEKMQEEEEKMQE-------QEEKIQRQEEKI---QEQEEKTWRQ-EKLLKQEEKIWE 500
Query: 290 AIVAEEDEEGRLDRQIGEIDEQIECYRRVEKLRNRQDEIKNKLKEILTIKELQKKEEENA 349
+E ++ RQ ++ EQ E + E+ RQ+E K++E +E++ ++E
Sbjct: 501 -------QEEKMWRQEEKMWEQEEKMQEQEEKMQRQEE---KMRE----QEVRLWQQEEK 546
Query: 350 DSDDEGELQDL 360
+ E LQ+L
Sbjct: 547 MQEQEVRLQEL 557
Score = 29.3 bits (64), Expect = 6.0
Identities = 34/161 (21%), Positives = 67/161 (41%), Gaps = 28/161 (17%)
Query: 222 HSGSIEKAEIHEKVVERRENTAEALPEGFFDDPEVDARVRKVDA-----PKDQMDKEWDE 276
+ +I E+ EK E +E E V RK++ P+ Q+ E D
Sbjct: 207 YRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADR 266
Query: 277 FQKAMRQVNTISEAIVAEED--------EEGRLDRQIGEIDEQIE--------------- 313
K ++ V+ +A V E + +E ++ RQ +I EQ E
Sbjct: 267 LGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEK 326
Query: 314 CYRRVEKLRNRQDEIKNKLKEILTIKELQKKEEENADSDDE 354
+R+ EK+ ++++I+ + ++ +E +++EE +E
Sbjct: 327 MWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEE 367
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 42.0 bits (97), Expect = 9e-04
Identities = 29/140 (20%), Positives = 69/140 (49%), Gaps = 11/140 (7%)
Query: 233 EKVVERRENTAEALPEGFFDDPEVDARVRKVDAPKDQMDKEWDEFQKAMRQVNTISEAIV 292
EK+ E+ E E + + + ++ + K+ +++M W + +K Q E +
Sbjct: 353 EKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEM---WRQEEKIREQEEKRQEKMW 409
Query: 293 AEEDEEGRLDRQIGEIDEQIECYRRVEKLRNRQDEIKNKLKEILTIKELQKKEEENADSD 352
+E + D +I E +E E +R+ EK+R ++ ++++ +++ ++E ++EEE
Sbjct: 410 RQEKKMREQDEKIREQEE--EMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQ 467
Query: 353 DEG------ELQDLLSQDWR 366
+E ++Q+ + WR
Sbjct: 468 EEKIQRQEEKIQEQEEKTWR 487
Score = 37.7 bits (86), Expect = 0.017
Identities = 25/107 (23%), Positives = 57/107 (53%), Gaps = 9/107 (8%)
Query: 267 KDQMDKEWDEFQKAMRQVNTISEAIVAEEDEEGRLDRQIGEIDEQI-----ECYRRVEKL 321
++Q +K W + +K Q I E +ED+ R + +I E +E+I + +R+ EK+
Sbjct: 321 REQEEKMWRQEEKMHEQEEKIRE----QEDKMWRQEEKIREQEEKIREQEEKMWRQEEKI 376
Query: 322 RNRQDEIKNKLKEILTIKELQKKEEENADSDDEGELQDLLSQDWRVK 368
R + ++I+ + +E+ +E +++EE + + + QD +++
Sbjct: 377 REQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIR 423
Score = 35.4 bits (80), Expect = 0.083
Identities = 29/130 (22%), Positives = 64/130 (49%), Gaps = 8/130 (6%)
Query: 233 EKVVERRENTAEALPEGFFDDPEVDARVRKVDAPKDQMDKEWDEFQKAMR----QVNTIS 288
EK+ E+ E E + E D ++R+ + + +++ E ++ M+ ++ +
Sbjct: 395 EKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVE 454
Query: 289 EAIVAEED----EEGRLDRQIGEIDEQIECYRRVEKLRNRQDEIKNKLKEILTIKELQKK 344
E + EE+ +E ++ RQ +I EQ E R EKL ++++I + +++ +E +
Sbjct: 455 EKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWE 514
Query: 345 EEENADSDDE 354
+EE +E
Sbjct: 515 QEEKMQEQEE 524
Score = 34.7 bits (78), Expect = 0.14
Identities = 23/125 (18%), Positives = 67/125 (53%), Gaps = 4/125 (3%)
Query: 230 EIHEKVVERRENTAEALPEGFFDDPEVDARVRKVDAPKDQMDKEWDEFQKAMRQVNTISE 289
E EK+ E+ E + + + ++ + K+ +D+M ++ ++ ++ ++ E
Sbjct: 308 EQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEE 367
Query: 290 AIVAEEDEEGRLDRQIGEIDEQIECYRRVEKLRNRQDEIKNKLKEILTIKELQKKEEENA 349
+ +E++ D +I E +E E +R+ EK+R ++++ + K+ K++++++E+
Sbjct: 368 KMWRQEEKIREQDEKIQEQEE--EMWRQEEKIREQEEKRQEKMWR--QEKKMREQDEKIR 423
Query: 350 DSDDE 354
+ ++E
Sbjct: 424 EQEEE 428
Score = 30.4 bits (67), Expect = 2.7
Identities = 32/131 (24%), Positives = 63/131 (48%), Gaps = 25/131 (19%)
Query: 230 EIHEKVVERRENTAEALPEGFFDDPEVDARVRKVDAPKDQMDKEWDEFQKAMRQVNTISE 289
E+ EK+ E E E + ++ + K+ ++Q +K W + +K ++Q I E
Sbjct: 452 EVEEKMQEEEEKMQE-------QEEKIQRQEEKI---QEQEEKTWRQ-EKLLKQEEKIWE 500
Query: 290 AIVAEEDEEGRLDRQIGEIDEQIECYRRVEKLRNRQDEIKNKLKEILTIKELQKKEEENA 349
+E ++ RQ ++ EQ E + E+ RQ+E K++E +E++ ++E
Sbjct: 501 -------QEEKMWRQEEKMWEQEEKMQEQEEKMQRQEE---KMRE----QEVRLWQQEEK 546
Query: 350 DSDDEGELQDL 360
+ E LQ+L
Sbjct: 547 MQEQEVRLQEL 557
Score = 29.3 bits (64), Expect = 6.0
Identities = 34/161 (21%), Positives = 67/161 (41%), Gaps = 28/161 (17%)
Query: 222 HSGSIEKAEIHEKVVERRENTAEALPEGFFDDPEVDARVRKVDA-----PKDQMDKEWDE 276
+ +I E+ EK E +E E V RK++ P+ Q+ E D
Sbjct: 207 YRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADR 266
Query: 277 FQKAMRQVNTISEAIVAEED--------EEGRLDRQIGEIDEQIE--------------- 313
K ++ V+ +A V E + +E ++ RQ +I EQ E
Sbjct: 267 LGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEK 326
Query: 314 CYRRVEKLRNRQDEIKNKLKEILTIKELQKKEEENADSDDE 354
+R+ EK+ ++++I+ + ++ +E +++EE +E
Sbjct: 327 MWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEE 367
>gi|15149463 caldesmon 1 isoform 4 [Homo sapiens]
Length = 558
Score = 42.0 bits (97), Expect = 9e-04
Identities = 56/234 (23%), Positives = 98/234 (41%), Gaps = 44/234 (18%)
Query: 156 LPDYEDEEEEEEEEEGDGERKRGDASKPLSDAQGKEHSVSSSREVTSSVLPNDFFSTNPP 215
LP + + E E + E K S+++ + + + + VT S ND+
Sbjct: 126 LPSRRMQNDTAENETTEKEEK--------SESRQERYEIEETETVTKSYQKNDWRDAEEN 177
Query: 216 KAPII---------PHSGSIEKAEIHEK---VVERRENTAEALPEGFFDDPEV-DARVRK 262
K P GSI + + EK V +RE E P F E+ D +++K
Sbjct: 178 KKEDKEKEEEEEEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPT--FKKEEIKDEKIKK 235
Query: 263 VDAPKDQMDKEWDEFQKAMRQVNTIS-----------EAIVAEEDEEGRLDRQIGEIDEQ 311
PK+++ K + + +K +V + + E + +D + E Q
Sbjct: 236 DKEPKEEV-KSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQ 294
Query: 312 IECYRRVEKLRNRQDEIKN----KLKE-----ILTIKELQKKEEENADSDDEGE 356
+E +R+E+LR R+ E ++ KLK+ L ++EL+KK EE +E E
Sbjct: 295 VEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEE 348
Score = 36.6 bits (83), Expect = 0.037
Identities = 50/212 (23%), Positives = 85/212 (40%), Gaps = 29/212 (13%)
Query: 153 LSLLPDYEDEEEEEEEEEGDGERKRGDASKPLSDAQGKEHSVSSSREVTSSVLPNDFFST 212
L+ L + +++EEE ER+R + L Q +E S +VT V N S
Sbjct: 13 LAALSQIAYQRNDDDEEEAARERRRRARQERLRQKQEEE----SLGQVTDQVEVNAQNSV 68
Query: 213 NPPKAPIIPHSGSIE---KAEIHEKVVERRENTAEALPEGFFDDPEVDARV--RKVDAPK 267
+A + +E +A E++ R E + L E E D + + P
Sbjct: 69 PDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPS 128
Query: 268 DQMDKEWDEFQKAMRQVNTISEAIVAEEDEEGRLDR-QIGEIDEQIECYRRVEKLRNRQD 326
+M + E +E EE E R +R +I E + + Y++ + +D
Sbjct: 129 RRMQNDTAE-----------NETTEKEEKSESRQERYEIEETETVTKSYQK----NDWRD 173
Query: 327 EIKNKLKEILTIKELQKKEEENADSDDEGELQ 358
+NK ++ KE +++EEE GE Q
Sbjct: 174 AEENKKED----KEKEEEEEEKPKRGSIGENQ 201
>gi|15149467 caldesmon 1 isoform 3 [Homo sapiens]
Length = 564
Score = 42.0 bits (97), Expect = 9e-04
Identities = 56/234 (23%), Positives = 98/234 (41%), Gaps = 44/234 (18%)
Query: 156 LPDYEDEEEEEEEEEGDGERKRGDASKPLSDAQGKEHSVSSSREVTSSVLPNDFFSTNPP 215
LP + + E E + E K S+++ + + + + VT S ND+
Sbjct: 132 LPSRRMQNDTAENETTEKEEK--------SESRQERYEIEETETVTKSYQKNDWRDAEEN 183
Query: 216 KAPII---------PHSGSIEKAEIHEK---VVERRENTAEALPEGFFDDPEV-DARVRK 262
K P GSI + + EK V +RE E P F E+ D +++K
Sbjct: 184 KKEDKEKEEEEEEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPT--FKKEEIKDEKIKK 241
Query: 263 VDAPKDQMDKEWDEFQKAMRQVNTIS-----------EAIVAEEDEEGRLDRQIGEIDEQ 311
PK+++ K + + +K +V + + E + +D + E Q
Sbjct: 242 DKEPKEEV-KSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQ 300
Query: 312 IECYRRVEKLRNRQDEIKN----KLKE-----ILTIKELQKKEEENADSDDEGE 356
+E +R+E+LR R+ E ++ KLK+ L ++EL+KK EE +E E
Sbjct: 301 VEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEE 354
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.307 0.126 0.345
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,950,097
Number of Sequences: 37866
Number of extensions: 740076
Number of successful extensions: 13441
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 251
Number of HSP's successfully gapped in prelim test: 514
Number of HSP's that attempted gapping in prelim test: 8515
Number of HSP's gapped (non-prelim): 3080
length of query: 372
length of database: 18,247,518
effective HSP length: 104
effective length of query: 268
effective length of database: 14,309,454
effective search space: 3834933672
effective search space used: 3834933672
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.