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Search of human proteins with 109638751
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|109638751 ubiquitin specific protease 6 [Homo sapiens]
(1406 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|109638751 ubiquitin specific protease 6 [Homo sapiens] 2921 0.0
gi|22550104 ubiquitin specific protease 32 [Homo sapiens] 1753 0.0
gi|183583563 TBC1 domain family, member 3D [Homo sapiens] 847 0.0
gi|157502205 TBC1 domain family, member 3G [Homo sapiens] 845 0.0
gi|183583565 TBC1 domain family, member 3 [Homo sapiens] 845 0.0
gi|183583567 TBC1 domain family, member 3E [Homo sapiens] 845 0.0
gi|226693407 TBC1 domain family, member 3H [Homo sapiens] 844 0.0
gi|90577185 TBC1 domain family member 3C [Homo sapiens] 842 0.0
gi|14149985 TBC1 domain family, member 3F [Homo sapiens] 842 0.0
gi|149999613 TBC1 domain family, member 3B [Homo sapiens] 841 0.0
gi|239756926 PREDICTED: similar to TBC1 domain family, member 3 ... 332 2e-90
gi|14149627 ubiquitin specific peptidase 15 [Homo sapiens] 266 1e-70
gi|7661864 USP6 N-terminal like isoform 1 [Homo sapiens] 264 4e-70
gi|122937432 USP6 N-terminal like isoform 2 [Homo sapiens] 264 4e-70
gi|40795667 ubiquitin specific protease 4 isoform b [Homo sapiens] 262 2e-69
gi|40795665 ubiquitin specific protease 4 isoform a [Homo sapiens] 256 1e-67
gi|24234683 ubiquitin specific peptidase 11 [Homo sapiens] 251 3e-66
gi|148235002 TBC1 domain family, member 26 [Homo sapiens] 241 3e-63
gi|57529246 ubiquitin thioesterase 19 [Homo sapiens] 198 3e-50
gi|239751420 PREDICTED: similar to hCG2039376 [Homo sapiens] 192 2e-48
gi|239745813 PREDICTED: hypothetical protein XP_002343595 [Homo ... 186 1e-46
gi|239756790 PREDICTED: similar to hCG1991532 [Homo sapiens] 181 3e-45
gi|151108489 TBC1 domain family, member 28 [Homo sapiens] 179 2e-44
gi|239756750 PREDICTED: similar to TBC1 domain family, member 28... 172 2e-42
gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens] 167 5e-41
gi|190684692 ubiquitin specific peptidase 8 [Homo sapiens] 167 5e-41
gi|190684690 ubiquitin specific peptidase 8 [Homo sapiens] 167 5e-41
gi|188528692 ubiquitin specific peptidase 2 isoform a [Homo sapi... 152 2e-36
gi|28565285 ubiquitin specific peptidase 2 isoform b [Homo sapiens] 152 2e-36
gi|239751314 PREDICTED: hypothetical protein XP_002347802 [Homo ... 149 2e-35
>gi|109638751 ubiquitin specific protease 6 [Homo sapiens]
Length = 1406
Score = 2921 bits (7573), Expect = 0.0
Identities = 1406/1406 (100%), Positives = 1406/1406 (100%)
Query: 1 MDMVENADSLQAQERKDILMKYDKGHRAGLPEDKGPEPVGINSSIDRFGILHETELPPVT 60
MDMVENADSLQAQERKDILMKYDKGHRAGLPEDKGPEPVGINSSIDRFGILHETELPPVT
Sbjct: 1 MDMVENADSLQAQERKDILMKYDKGHRAGLPEDKGPEPVGINSSIDRFGILHETELPPVT 60
Query: 61 AREAKKIRREMTRTSKWMEMLGEWETYKHSSKLIDRVYKGIPMNIRGPVWSVLLNIQEIK 120
AREAKKIRREMTRTSKWMEMLGEWETYKHSSKLIDRVYKGIPMNIRGPVWSVLLNIQEIK
Sbjct: 61 AREAKKIRREMTRTSKWMEMLGEWETYKHSSKLIDRVYKGIPMNIRGPVWSVLLNIQEIK 120
Query: 121 LKNPGRYQIMKERGKRSSEHIHHIDLDVRTTLRNHVFFRDRYGAKQRELFYILLAYSEYN 180
LKNPGRYQIMKERGKRSSEHIHHIDLDVRTTLRNHVFFRDRYGAKQRELFYILLAYSEYN
Sbjct: 121 LKNPGRYQIMKERGKRSSEHIHHIDLDVRTTLRNHVFFRDRYGAKQRELFYILLAYSEYN 180
Query: 181 PEVGYCRDLSHITALFLLYLPEEDAFWALVQLLASERHSLPGFHSPNGGTVQGLQDQQEH 240
PEVGYCRDLSHITALFLLYLPEEDAFWALVQLLASERHSLPGFHSPNGGTVQGLQDQQEH
Sbjct: 181 PEVGYCRDLSHITALFLLYLPEEDAFWALVQLLASERHSLPGFHSPNGGTVQGLQDQQEH 240
Query: 241 VVPKSQPKTMWHQDKEGLCGQCASLGCLLRNLIDGISLGLTLRLWDVYLVEGEQVLMPIT 300
VVPKSQPKTMWHQDKEGLCGQCASLGCLLRNLIDGISLGLTLRLWDVYLVEGEQVLMPIT
Sbjct: 241 VVPKSQPKTMWHQDKEGLCGQCASLGCLLRNLIDGISLGLTLRLWDVYLVEGEQVLMPIT 300
Query: 301 SIALKVQQKRLMKTSRCGLWARLRNQFFDTWAMNDDTVLKHLRASTKKLTRKQGDLPPPA 360
SIALKVQQKRLMKTSRCGLWARLRNQFFDTWAMNDDTVLKHLRASTKKLTRKQGDLPPPA
Sbjct: 301 SIALKVQQKRLMKTSRCGLWARLRNQFFDTWAMNDDTVLKHLRASTKKLTRKQGDLPPPA 360
Query: 361 KREQGSLAPRPVPASRGGKTLCKGYRQAPPGPPAQFQRPICSASPPWASRFSTPCPGGAV 420
KREQGSLAPRPVPASRGGKTLCKGYRQAPPGPPAQFQRPICSASPPWASRFSTPCPGGAV
Sbjct: 361 KREQGSLAPRPVPASRGGKTLCKGYRQAPPGPPAQFQRPICSASPPWASRFSTPCPGGAV 420
Query: 421 REDTYPVGTQGVPSLALAQGGPQGSWRFLEWKSMPRLPTDLDIGGPWFPHYDFEWSCWVR 480
REDTYPVGTQGVPSLALAQGGPQGSWRFLEWKSMPRLPTDLDIGGPWFPHYDFEWSCWVR
Sbjct: 421 REDTYPVGTQGVPSLALAQGGPQGSWRFLEWKSMPRLPTDLDIGGPWFPHYDFEWSCWVR 480
Query: 481 AISQEDQLATCWQAEHCGEVHNKDMSWPEEMSFTANSSKIDRQKVPTEKGATGLSNLGNT 540
AISQEDQLATCWQAEHCGEVHNKDMSWPEEMSFTANSSKIDRQKVPTEKGATGLSNLGNT
Sbjct: 481 AISQEDQLATCWQAEHCGEVHNKDMSWPEEMSFTANSSKIDRQKVPTEKGATGLSNLGNT 540
Query: 541 CFMNSSIQCVSNTQPLTQYFISGRHLYELNRTNPIGMKGHMAKCYGDLVQELWSGTQKSV 600
CFMNSSIQCVSNTQPLTQYFISGRHLYELNRTNPIGMKGHMAKCYGDLVQELWSGTQKSV
Sbjct: 541 CFMNSSIQCVSNTQPLTQYFISGRHLYELNRTNPIGMKGHMAKCYGDLVQELWSGTQKSV 600
Query: 601 APLKLRRTIAKYAPKFDGFQQQDSQELLAFLLDGLHEDLNRVHEKPYVELKDSDGRPDWE 660
APLKLRRTIAKYAPKFDGFQQQDSQELLAFLLDGLHEDLNRVHEKPYVELKDSDGRPDWE
Sbjct: 601 APLKLRRTIAKYAPKFDGFQQQDSQELLAFLLDGLHEDLNRVHEKPYVELKDSDGRPDWE 660
Query: 661 VAAEAWDNHLRRNRSIIVDLFHGQLRSQVKCKTCGHISVRFDPFNFLSLPLPMDSYMDLE 720
VAAEAWDNHLRRNRSIIVDLFHGQLRSQVKCKTCGHISVRFDPFNFLSLPLPMDSYMDLE
Sbjct: 661 VAAEAWDNHLRRNRSIIVDLFHGQLRSQVKCKTCGHISVRFDPFNFLSLPLPMDSYMDLE 720
Query: 721 ITVIKLDGTTPVRYGLRLNMDEKYTGLKKQLRDLCGLNSEQILLAEVHDSNIKNFPQDNQ 780
ITVIKLDGTTPVRYGLRLNMDEKYTGLKKQLRDLCGLNSEQILLAEVHDSNIKNFPQDNQ
Sbjct: 721 ITVIKLDGTTPVRYGLRLNMDEKYTGLKKQLRDLCGLNSEQILLAEVHDSNIKNFPQDNQ 780
Query: 781 KVQLSVSGFLCAFEIPVPSSPISASSPTQIDFSSSPSTNGMFTLTTNGDLPKPIFIPNGM 840
KVQLSVSGFLCAFEIPVPSSPISASSPTQIDFSSSPSTNGMFTLTTNGDLPKPIFIPNGM
Sbjct: 781 KVQLSVSGFLCAFEIPVPSSPISASSPTQIDFSSSPSTNGMFTLTTNGDLPKPIFIPNGM 840
Query: 841 PNTVVPCGTEKNFTNGMVNGHMPSLPDSPFTGYIIAVHRKMMRTELYFLSPQENRPSLFG 900
PNTVVPCGTEKNFTNGMVNGHMPSLPDSPFTGYIIAVHRKMMRTELYFLSPQENRPSLFG
Sbjct: 841 PNTVVPCGTEKNFTNGMVNGHMPSLPDSPFTGYIIAVHRKMMRTELYFLSPQENRPSLFG 900
Query: 901 MPLIVPCTVHTRKKDLYDAVWIQVSWLARPLPPQEASIHAQDRDNCMGYQYPFTLRVVQK 960
MPLIVPCTVHTRKKDLYDAVWIQVSWLARPLPPQEASIHAQDRDNCMGYQYPFTLRVVQK
Sbjct: 901 MPLIVPCTVHTRKKDLYDAVWIQVSWLARPLPPQEASIHAQDRDNCMGYQYPFTLRVVQK 960
Query: 961 DGNSCAWCPQYRFCRGCKIDCGEDRAFIGNAYIAVDWHPTALHLRYQTSQERVVDKHESV 1020
DGNSCAWCPQYRFCRGCKIDCGEDRAFIGNAYIAVDWHPTALHLRYQTSQERVVDKHESV
Sbjct: 961 DGNSCAWCPQYRFCRGCKIDCGEDRAFIGNAYIAVDWHPTALHLRYQTSQERVVDKHESV 1020
Query: 1021 EQSRRAQAEPINLDSCLRAFTSEEELGESEMYYCSKCKTHCLATKKLDLWRLPPFLIIHL 1080
EQSRRAQAEPINLDSCLRAFTSEEELGESEMYYCSKCKTHCLATKKLDLWRLPPFLIIHL
Sbjct: 1021 EQSRRAQAEPINLDSCLRAFTSEEELGESEMYYCSKCKTHCLATKKLDLWRLPPFLIIHL 1080
Query: 1081 KRFQFVNDQWIKSQKIVRFLRESFDPSAFLVPRDPALCQHKPLTPQGDELSKPRILAREV 1140
KRFQFVNDQWIKSQKIVRFLRESFDPSAFLVPRDPALCQHKPLTPQGDELSKPRILAREV
Sbjct: 1081 KRFQFVNDQWIKSQKIVRFLRESFDPSAFLVPRDPALCQHKPLTPQGDELSKPRILAREV 1140
Query: 1141 KKVDAQSSAGKEDMLLSKSPSSLSANISSSPKGSPSSSRKSGTSCPSSKNSSPNSSPRTL 1200
KKVDAQSSAGKEDMLLSKSPSSLSANISSSPKGSPSSSRKSGTSCPSSKNSSPNSSPRTL
Sbjct: 1141 KKVDAQSSAGKEDMLLSKSPSSLSANISSSPKGSPSSSRKSGTSCPSSKNSSPNSSPRTL 1200
Query: 1201 GRSKGRLRLPQIGSKNKPSSSKKNLDASKENGAGQICELADALSRGHMRGGSQPELVTPQ 1260
GRSKGRLRLPQIGSKNKPSSSKKNLDASKENGAGQICELADALSRGHMRGGSQPELVTPQ
Sbjct: 1201 GRSKGRLRLPQIGSKNKPSSSKKNLDASKENGAGQICELADALSRGHMRGGSQPELVTPQ 1260
Query: 1261 DHEVALANGFLYEHEACGNGCGDGYSNGQLGNHSEEDSTDDQREDTHIKPIYNLYAISCH 1320
DHEVALANGFLYEHEACGNGCGDGYSNGQLGNHSEEDSTDDQREDTHIKPIYNLYAISCH
Sbjct: 1261 DHEVALANGFLYEHEACGNGCGDGYSNGQLGNHSEEDSTDDQREDTHIKPIYNLYAISCH 1320
Query: 1321 SGILSGGHYITYAKNPNCKWYCYNDSSCEELHPDEIDTDSAYILFYEQQGIDYAQFLPKI 1380
SGILSGGHYITYAKNPNCKWYCYNDSSCEELHPDEIDTDSAYILFYEQQGIDYAQFLPKI
Sbjct: 1321 SGILSGGHYITYAKNPNCKWYCYNDSSCEELHPDEIDTDSAYILFYEQQGIDYAQFLPKI 1380
Query: 1381 DGKKMADTSSTDEDSESDYEKYSMLQ 1406
DGKKMADTSSTDEDSESDYEKYSMLQ
Sbjct: 1381 DGKKMADTSSTDEDSESDYEKYSMLQ 1406
>gi|22550104 ubiquitin specific protease 32 [Homo sapiens]
Length = 1604
Score = 1753 bits (4541), Expect = 0.0
Identities = 853/908 (93%), Positives = 874/908 (96%), Gaps = 4/908 (0%)
Query: 499 EVHNKDMSWPEEMSFTANSSKIDRQKVPTEKGATGLSNLGNTCFMNSSIQCVSNTQPLTQ 558
EV NKDMSWPEEMSF ANSSKIDR KVPTEKGATGLSNLGNTCFMNSSIQCVSNTQPLTQ
Sbjct: 701 EVRNKDMSWPEEMSFIANSSKIDRHKVPTEKGATGLSNLGNTCFMNSSIQCVSNTQPLTQ 760
Query: 559 YFISGRHLYELNRTNPIGMKGHMAKCYGDLVQELWSGTQKSVAPLKLRRTIAKYAPKFDG 618
YFISGRHLYELNRTNPIGMKGHMAKCYGDLVQELWSGTQK+VAPLKLR TIAKYAP+F+G
Sbjct: 761 YFISGRHLYELNRTNPIGMKGHMAKCYGDLVQELWSGTQKNVAPLKLRWTIAKYAPRFNG 820
Query: 619 FQQQDSQELLAFLLDGLHEDLNRVHEKPYVELKDSDGRPDWEVAAEAWDNHLRRNRSIIV 678
FQQQDSQELLAFLLDGLHEDLNRVHEKPYVELKDSDGRPDWEVAAEAWDNHLRRNRSI+V
Sbjct: 821 FQQQDSQELLAFLLDGLHEDLNRVHEKPYVELKDSDGRPDWEVAAEAWDNHLRRNRSIVV 880
Query: 679 DLFHGQLRSQVKCKTCGHISVRFDPFNFLSLPLPMDSYMDLEITVIKLDGTTPVRYGLRL 738
DLFHGQLRSQVKCKTCGHISVRFDPFNFLSLPLPMDSYM LEITVIKLDGTTPVRYGLRL
Sbjct: 881 DLFHGQLRSQVKCKTCGHISVRFDPFNFLSLPLPMDSYMHLEITVIKLDGTTPVRYGLRL 940
Query: 739 NMDEKYTGLKKQLRDLCGLNSEQILLAEVHDSNIKNFPQDNQKVQLSVSGFLCAFEIPVP 798
NMDEKYTGLKKQL DLCGLNSEQILLAEVH SNIKNFPQDNQKV+LSVSGFLCAFEIPVP
Sbjct: 941 NMDEKYTGLKKQLSDLCGLNSEQILLAEVHGSNIKNFPQDNQKVRLSVSGFLCAFEIPVP 1000
Query: 799 SSPISASSPTQIDFSSSPSTNGMFTLTTNGDLPKPIFIPNGMPNTVVPCGTEKNFTNGMV 858
SPISASSPTQ DFSSSPSTN MFTLTTNGDLP+PIFIPNGMPNTVVPCGTEKNFTNGMV
Sbjct: 1001 VSPISASSPTQTDFSSSPSTNEMFTLTTNGDLPRPIFIPNGMPNTVVPCGTEKNFTNGMV 1060
Query: 859 NGHMPSLPDSPFTGYIIAVHRKMMRTELYFLSPQENRPSLFGMPLIVPCTVHTRKKDLYD 918
NGHMPSLPDSPFTGYIIAVHRKMMRTELYFLS Q+NRPSLFGMPLIVPCTVHTRKKDLYD
Sbjct: 1061 NGHMPSLPDSPFTGYIIAVHRKMMRTELYFLSSQKNRPSLFGMPLIVPCTVHTRKKDLYD 1120
Query: 919 AVWIQVSWLARPLPPQEASIHAQDRDNCMGYQYPFTLRVVQKDGNSCAWCPQYRFCRGCK 978
AVWIQVS LA PLPPQEAS HAQD D+ MGYQYPFTLRVVQKDGNSCAWCP YRFCRGCK
Sbjct: 1121 AVWIQVSRLASPLPPQEASNHAQDCDDSMGYQYPFTLRVVQKDGNSCAWCPWYRFCRGCK 1180
Query: 979 IDCGEDRAFIGNAYIAVDWHPTALHLRYQTSQERVVDKHESVEQSRRAQAEPINLDSCLR 1038
IDCGEDRAFIGNAYIAVDW PTALHLRYQTSQERVVD+HESVEQSRRAQAEPINLDSCLR
Sbjct: 1181 IDCGEDRAFIGNAYIAVDWDPTALHLRYQTSQERVVDEHESVEQSRRAQAEPINLDSCLR 1240
Query: 1039 AFTSEEELGESEMYYCSKCKTHCLATKKLDLWRLPPFLIIHLKRFQFVNDQWIKSQKIVR 1098
AFTSEEELGE+EMYYCSKCKTHCLATKKLDLWRLPP LIIHLKRFQFVN +WIKSQKIV+
Sbjct: 1241 AFTSEEELGENEMYYCSKCKTHCLATKKLDLWRLPPILIIHLKRFQFVNGRWIKSQKIVK 1300
Query: 1099 FLRESFDPSAFLVPRDPALCQHKPLTPQGDELSKPRILAREVKKVDAQSSAGKEDMLLSK 1158
F RESFDPSAFLVPRDPALCQHKPLTPQGDELS+PRILAREVKKVDAQSSAG+ED+LLSK
Sbjct: 1301 FPRESFDPSAFLVPRDPALCQHKPLTPQGDELSEPRILAREVKKVDAQSSAGEEDVLLSK 1360
Query: 1159 SPSSLSANISSSPKGSPSSSRKSGTSCPSSKNSSPNSSPRTLGRSKGRLRLPQIGSKNKP 1218
SPSSLSANI SSPKGSPSSSRKSGTSCPSSKNSSPNSSPRTLGRSKGRLRLPQIGSKNK
Sbjct: 1361 SPSSLSANIISSPKGSPSSSRKSGTSCPSSKNSSPNSSPRTLGRSKGRLRLPQIGSKNKL 1420
Query: 1219 SSSKKNLDASKENGAGQICELADALSRGHMRGGSQPELVTPQDHEVALANGFLYEHEACG 1278
SSSK+NLDASKENGAGQICELADALSRGH+ GGSQPELVTPQDHEVALANGFLYEHEACG
Sbjct: 1421 SSSKENLDASKENGAGQICELADALSRGHVLGGSQPELVTPQDHEVALANGFLYEHEACG 1480
Query: 1279 NGCGDGYSNGQLGNHSEEDSTDDQREDTHIKPIYNLYAISCHSGILSGGHYITYAKNPNC 1338
N GYSNGQLGNHSEEDSTDDQREDT IKPIYNLYAISCHSGIL GGHY+TYAKNPNC
Sbjct: 1481 N----GYSNGQLGNHSEEDSTDDQREDTRIKPIYNLYAISCHSGILGGGHYVTYAKNPNC 1536
Query: 1339 KWYCYNDSSCEELHPDEIDTDSAYILFYEQQGIDYAQFLPKIDGKKMADTSSTDEDSESD 1398
KWYCYNDSSC+ELHPDEIDTDSAYILFYEQQGIDYAQFLPK DGKKMADTSS DED ESD
Sbjct: 1537 KWYCYNDSSCKELHPDEIDTDSAYILFYEQQGIDYAQFLPKTDGKKMADTSSMDEDFESD 1596
Query: 1399 YEKYSMLQ 1406
Y+KY +LQ
Sbjct: 1597 YKKYCVLQ 1604
>gi|183583563 TBC1 domain family, member 3D [Homo sapiens]
Length = 549
Score = 847 bits (2187), Expect = 0.0
Identities = 408/500 (81%), Positives = 440/500 (88%), Gaps = 1/500 (0%)
Query: 1 MDMVENADSLQAQERKDILMKYDKGHRAGLPEDKGPEPV-GINSSIDRFGILHETELPPV 59
MD+VE A S AQER+DI+MKY+KGHRAGLPEDKGP+P N+++D GI+HETELPP+
Sbjct: 1 MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL 60
Query: 60 TAREAKKIRREMTRTSKWMEMLGEWETYKHSSKLIDRVYKGIPMNIRGPVWSVLLNIQEI 119
TAREAK+IRRE++R SKW++MLG+WE YK S KLIDR YKG+PMNIRGP+WSVLLNI+E+
Sbjct: 61 TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEM 120
Query: 120 KLKNPGRYQIMKERGKRSSEHIHHIDLDVRTTLRNHVFFRDRYGAKQRELFYILLAYSEY 179
KLKNPGRYQIMKE+GKRSSEHI ID DV TLR H+FFRDRYG KQREL +ILLAY EY
Sbjct: 121 KLKNPGRYQIMKEKGKRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEY 180
Query: 180 NPEVGYCRDLSHITALFLLYLPEEDAFWALVQLLASERHSLPGFHSPNGGTVQGLQDQQE 239
NPEVGYCRDLSHI ALFLLYLPEEDAFWALVQLLASERHSL GFHSPNGGTVQGLQDQQE
Sbjct: 181 NPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQE 240
Query: 240 HVVPKSQPKTMWHQDKEGLCGQCASLGCLLRNLIDGISLGLTLRLWDVYLVEGEQVLMPI 299
HVV SQPKTM HQDK+ LCGQC+ LGCL+R LIDGISLGLTLRLWDVYLVEGEQ LMPI
Sbjct: 241 HVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPI 300
Query: 300 TSIALKVQQKRLMKTSRCGLWARLRNQFFDTWAMNDDTVLKHLRASTKKLTRKQGDLPPP 359
T IA KVQQKRL KTSRCG WAR N+F DTWA ++DTVLKHLRAS KKLTRKQGDLPPP
Sbjct: 301 TRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPP 360
Query: 360 AKREQGSLAPRPVPASRGGKTLCKGYRQAPPGPPAQFQRPICSASPPWASRFSTPCPGGA 419
AK EQGS A RPVPASRGGKTLCKG RQAPPGPPA+F RPI SASPP A R STPCPGGA
Sbjct: 361 AKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGA 420
Query: 420 VREDTYPVGTQGVPSLALAQGGPQGSWRFLEWKSMPRLPTDLDIGGPWFPHYDFEWSCWV 479
VREDTYPVGTQGVPS ALAQGGPQGSWRFL+W SMPRLPTDLD+ GPWF HYDF SCWV
Sbjct: 421 VREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWV 480
Query: 480 RAISQEDQLATCWQAEHCGE 499
RAISQEDQLA CWQAEH E
Sbjct: 481 RAISQEDQLAPCWQAEHPAE 500
>gi|157502205 TBC1 domain family, member 3G [Homo sapiens]
Length = 549
Score = 845 bits (2184), Expect = 0.0
Identities = 407/500 (81%), Positives = 440/500 (88%), Gaps = 1/500 (0%)
Query: 1 MDMVENADSLQAQERKDILMKYDKGHRAGLPEDKGPEPV-GINSSIDRFGILHETELPPV 59
MD+VE A S AQER+DI+MKY+KGHRAGLPEDKGP+P N+++D GI+HETELPP+
Sbjct: 1 MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL 60
Query: 60 TAREAKKIRREMTRTSKWMEMLGEWETYKHSSKLIDRVYKGIPMNIRGPVWSVLLNIQEI 119
TAREAK+IRRE++R SKW++MLG+WE YK S KLIDR YKG+PMNIRGP+WSVLLNI+E+
Sbjct: 61 TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEM 120
Query: 120 KLKNPGRYQIMKERGKRSSEHIHHIDLDVRTTLRNHVFFRDRYGAKQRELFYILLAYSEY 179
KLKNPGRYQIMKE+GKRSSEHI ID D+ TLR H+FFRDRYG KQREL +ILLAY EY
Sbjct: 121 KLKNPGRYQIMKEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEY 180
Query: 180 NPEVGYCRDLSHITALFLLYLPEEDAFWALVQLLASERHSLPGFHSPNGGTVQGLQDQQE 239
NPEVGYCRDLSHI ALFLLYLPEEDAFWALVQLLASERHSL GFHSPNGGTVQGLQDQQE
Sbjct: 181 NPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQE 240
Query: 240 HVVPKSQPKTMWHQDKEGLCGQCASLGCLLRNLIDGISLGLTLRLWDVYLVEGEQVLMPI 299
HVV SQPKTM HQDK+ LCGQC+ LGCL+R LIDGISLGLTLRLWDVYLVEGEQ LMPI
Sbjct: 241 HVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPI 300
Query: 300 TSIALKVQQKRLMKTSRCGLWARLRNQFFDTWAMNDDTVLKHLRASTKKLTRKQGDLPPP 359
T IA KVQQKRL KTSRCG WAR N+F DTWA ++DTVLKHLRAS KKLTRKQGDLPPP
Sbjct: 301 TRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPP 360
Query: 360 AKREQGSLAPRPVPASRGGKTLCKGYRQAPPGPPAQFQRPICSASPPWASRFSTPCPGGA 419
AK EQGS A RPVPASRGGKTLCKG RQAPPGPPA+F RPI SASPP A R STPCPGGA
Sbjct: 361 AKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGA 420
Query: 420 VREDTYPVGTQGVPSLALAQGGPQGSWRFLEWKSMPRLPTDLDIGGPWFPHYDFEWSCWV 479
VREDTYPVGTQGVPS ALAQGGPQGSWRFL+W SMPRLPTDLD+ GPWF HYDF SCWV
Sbjct: 421 VREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWV 480
Query: 480 RAISQEDQLATCWQAEHCGE 499
RAISQEDQLA CWQAEH E
Sbjct: 481 RAISQEDQLAPCWQAEHPAE 500
>gi|183583565 TBC1 domain family, member 3 [Homo sapiens]
Length = 549
Score = 845 bits (2183), Expect = 0.0
Identities = 407/500 (81%), Positives = 440/500 (88%), Gaps = 1/500 (0%)
Query: 1 MDMVENADSLQAQERKDILMKYDKGHRAGLPEDKGPEPV-GINSSIDRFGILHETELPPV 59
MD+VE A S AQER+DI+MKY+KGHRAGLPEDKGP+P N+++D GI+HETELPP+
Sbjct: 1 MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL 60
Query: 60 TAREAKKIRREMTRTSKWMEMLGEWETYKHSSKLIDRVYKGIPMNIRGPVWSVLLNIQEI 119
TAREAK+IRRE++R SKW++MLG+WE YK S KLIDR YKG+PMNIRGP+WSVLLNI+E+
Sbjct: 61 TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEM 120
Query: 120 KLKNPGRYQIMKERGKRSSEHIHHIDLDVRTTLRNHVFFRDRYGAKQRELFYILLAYSEY 179
KLKNPGRYQIMKE+GKRSSEHI ID DV TLR H+FFRDRYG KQREL +ILLAY EY
Sbjct: 121 KLKNPGRYQIMKEKGKRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEY 180
Query: 180 NPEVGYCRDLSHITALFLLYLPEEDAFWALVQLLASERHSLPGFHSPNGGTVQGLQDQQE 239
NPEVGYCRDLSHI ALFLLYLPEEDAFWALVQLLASERHSL GFHSPNGGTVQGLQDQQE
Sbjct: 181 NPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQE 240
Query: 240 HVVPKSQPKTMWHQDKEGLCGQCASLGCLLRNLIDGISLGLTLRLWDVYLVEGEQVLMPI 299
HVV SQPKTM HQDK+ LCGQC+ LGCL+R LIDGISLGLTLRLWDVYLVEGEQ LMPI
Sbjct: 241 HVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPI 300
Query: 300 TSIALKVQQKRLMKTSRCGLWARLRNQFFDTWAMNDDTVLKHLRASTKKLTRKQGDLPPP 359
T IA KVQQKRL KTSRCG WAR N+F DTWA ++DTVLKHLRAS KKLTRK+GDLPPP
Sbjct: 301 TRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKKGDLPPP 360
Query: 360 AKREQGSLAPRPVPASRGGKTLCKGYRQAPPGPPAQFQRPICSASPPWASRFSTPCPGGA 419
AK EQGS A RPVPASRGGKTLCKG RQAPPGPPA+F RPI SASPP A R STPCPGGA
Sbjct: 361 AKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGA 420
Query: 420 VREDTYPVGTQGVPSLALAQGGPQGSWRFLEWKSMPRLPTDLDIGGPWFPHYDFEWSCWV 479
VREDTYPVGTQGVPS ALAQGGPQGSWRFL+W SMPRLPTDLD+ GPWF HYDF SCWV
Sbjct: 421 VREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWV 480
Query: 480 RAISQEDQLATCWQAEHCGE 499
RAISQEDQLA CWQAEH E
Sbjct: 481 RAISQEDQLAPCWQAEHPAE 500
>gi|183583567 TBC1 domain family, member 3E [Homo sapiens]
Length = 549
Score = 845 bits (2183), Expect = 0.0
Identities = 407/500 (81%), Positives = 440/500 (88%), Gaps = 1/500 (0%)
Query: 1 MDMVENADSLQAQERKDILMKYDKGHRAGLPEDKGPEPV-GINSSIDRFGILHETELPPV 59
MD+VE A S AQER+DI+MKY+KGHRAGLPEDKGP+P N+++D GI+HETELPP+
Sbjct: 1 MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL 60
Query: 60 TAREAKKIRREMTRTSKWMEMLGEWETYKHSSKLIDRVYKGIPMNIRGPVWSVLLNIQEI 119
TAREAK+IRRE++R SKW++MLG+WE YK S KLIDR YKG+PMNIRGP+WSVLLNI+E+
Sbjct: 61 TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEM 120
Query: 120 KLKNPGRYQIMKERGKRSSEHIHHIDLDVRTTLRNHVFFRDRYGAKQRELFYILLAYSEY 179
KLKNPGRYQIMKE+GKRSSEHI ID DV TLR H+FFRDRYG KQREL +ILLAY EY
Sbjct: 121 KLKNPGRYQIMKEKGKRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEY 180
Query: 180 NPEVGYCRDLSHITALFLLYLPEEDAFWALVQLLASERHSLPGFHSPNGGTVQGLQDQQE 239
NPEVGYCRDLSHI ALFLLYLPEEDAFWALVQLLASERHSL GFHSPNGGTVQGLQDQQE
Sbjct: 181 NPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQE 240
Query: 240 HVVPKSQPKTMWHQDKEGLCGQCASLGCLLRNLIDGISLGLTLRLWDVYLVEGEQVLMPI 299
HVV SQPKTM HQDK+ LCGQC+ LGCL+R LIDGISLGLTLRLWDVYLVEGEQ LMPI
Sbjct: 241 HVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPI 300
Query: 300 TSIALKVQQKRLMKTSRCGLWARLRNQFFDTWAMNDDTVLKHLRASTKKLTRKQGDLPPP 359
T IA KVQQKRL KTSRCG WAR N+F DTWA ++DTVLKHLRAS KKLTRK+GDLPPP
Sbjct: 301 TRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKKGDLPPP 360
Query: 360 AKREQGSLAPRPVPASRGGKTLCKGYRQAPPGPPAQFQRPICSASPPWASRFSTPCPGGA 419
AK EQGS A RPVPASRGGKTLCKG RQAPPGPPA+F RPI SASPP A R STPCPGGA
Sbjct: 361 AKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGA 420
Query: 420 VREDTYPVGTQGVPSLALAQGGPQGSWRFLEWKSMPRLPTDLDIGGPWFPHYDFEWSCWV 479
VREDTYPVGTQGVPS ALAQGGPQGSWRFL+W SMPRLPTDLD+ GPWF HYDF SCWV
Sbjct: 421 VREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWV 480
Query: 480 RAISQEDQLATCWQAEHCGE 499
RAISQEDQLA CWQAEH E
Sbjct: 481 RAISQEDQLAPCWQAEHPAE 500
>gi|226693407 TBC1 domain family, member 3H [Homo sapiens]
Length = 549
Score = 844 bits (2180), Expect = 0.0
Identities = 406/500 (81%), Positives = 440/500 (88%), Gaps = 1/500 (0%)
Query: 1 MDMVENADSLQAQERKDILMKYDKGHRAGLPEDKGPEPV-GINSSIDRFGILHETELPPV 59
MD+VE A S AQER+DI+MKY+KGH+AGLPEDKGP+P N+++D GI+HETELPP+
Sbjct: 1 MDVVEVAGSWWAQEREDIIMKYEKGHQAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL 60
Query: 60 TAREAKKIRREMTRTSKWMEMLGEWETYKHSSKLIDRVYKGIPMNIRGPVWSVLLNIQEI 119
TAREAK+IRRE++R SKW++MLG+WE YK S KLIDR YKG+PMNIRGP+WSVLLNI+E+
Sbjct: 61 TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEM 120
Query: 120 KLKNPGRYQIMKERGKRSSEHIHHIDLDVRTTLRNHVFFRDRYGAKQRELFYILLAYSEY 179
KLKNPGRYQIMKE+GKRSSEHI ID D+ TLR H+FFRDRYG KQREL +ILLAY EY
Sbjct: 121 KLKNPGRYQIMKEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEY 180
Query: 180 NPEVGYCRDLSHITALFLLYLPEEDAFWALVQLLASERHSLPGFHSPNGGTVQGLQDQQE 239
NPEVGYCRDLSHI ALFLLYLPEEDAFWALVQLLASERHSL GFHSPNGGTVQGLQDQQE
Sbjct: 181 NPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQE 240
Query: 240 HVVPKSQPKTMWHQDKEGLCGQCASLGCLLRNLIDGISLGLTLRLWDVYLVEGEQVLMPI 299
HVV SQPKTM HQDK+ LCGQC+ LGCL+R LIDGISLGLTLRLWDVYLVEGEQ LMPI
Sbjct: 241 HVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPI 300
Query: 300 TSIALKVQQKRLMKTSRCGLWARLRNQFFDTWAMNDDTVLKHLRASTKKLTRKQGDLPPP 359
T IA KVQQKRL KTSRCG WAR N+F DTWA ++DTVLKHLRAS KKLTRKQGDLPPP
Sbjct: 301 TRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPP 360
Query: 360 AKREQGSLAPRPVPASRGGKTLCKGYRQAPPGPPAQFQRPICSASPPWASRFSTPCPGGA 419
AK EQGS A RPVPASRGGKTLCKG RQAPPGPPA+F RPI SASPP A R STPCPGGA
Sbjct: 361 AKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGA 420
Query: 420 VREDTYPVGTQGVPSLALAQGGPQGSWRFLEWKSMPRLPTDLDIGGPWFPHYDFEWSCWV 479
VREDTYPVGTQGVPS ALAQGGPQGSWRFL+W SMPRLPTDLD+ GPWF HYDF SCWV
Sbjct: 421 VREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWV 480
Query: 480 RAISQEDQLATCWQAEHCGE 499
RAISQEDQLA CWQAEH E
Sbjct: 481 RAISQEDQLAPCWQAEHPAE 500
>gi|90577185 TBC1 domain family member 3C [Homo sapiens]
Length = 549
Score = 842 bits (2176), Expect = 0.0
Identities = 406/500 (81%), Positives = 439/500 (87%), Gaps = 1/500 (0%)
Query: 1 MDMVENADSLQAQERKDILMKYDKGHRAGLPEDKGPEPV-GINSSIDRFGILHETELPPV 59
MD+VE A S AQER+DI+MKY+KGHRAGLPEDKGP+P N+++D GI+HETELPP+
Sbjct: 1 MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL 60
Query: 60 TAREAKKIRREMTRTSKWMEMLGEWETYKHSSKLIDRVYKGIPMNIRGPVWSVLLNIQEI 119
TAREAK+IRRE++R SKW++MLG+WE YK S KLIDR YKG+PMNIRGP+WSVLLNI+E+
Sbjct: 61 TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEM 120
Query: 120 KLKNPGRYQIMKERGKRSSEHIHHIDLDVRTTLRNHVFFRDRYGAKQRELFYILLAYSEY 179
KLKNPGRYQIMKE+GKRSSEHI ID D+ TLR H+FFRDRYG KQREL +ILLAY EY
Sbjct: 121 KLKNPGRYQIMKEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEY 180
Query: 180 NPEVGYCRDLSHITALFLLYLPEEDAFWALVQLLASERHSLPGFHSPNGGTVQGLQDQQE 239
NPEVGYCRDLSHI ALFLLYLPEEDAFWALVQLLASERHSL GFHSPNGGTVQGLQDQQE
Sbjct: 181 NPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQE 240
Query: 240 HVVPKSQPKTMWHQDKEGLCGQCASLGCLLRNLIDGISLGLTLRLWDVYLVEGEQVLMPI 299
HVV SQ KTM HQDK+ LCGQC+ LGCL+R LIDGISLGLTLRLWDVYLVEGEQ LMPI
Sbjct: 241 HVVATSQSKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPI 300
Query: 300 TSIALKVQQKRLMKTSRCGLWARLRNQFFDTWAMNDDTVLKHLRASTKKLTRKQGDLPPP 359
T IA KVQQKRL KTSRCG WAR N+F DTWA ++DTVLKHLRAS KKLTRKQGDLPPP
Sbjct: 301 TRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPP 360
Query: 360 AKREQGSLAPRPVPASRGGKTLCKGYRQAPPGPPAQFQRPICSASPPWASRFSTPCPGGA 419
AK EQGS A RPVPASRGGKTLCKG RQAPPGPPA+F RPI SASPP A R STPCPGGA
Sbjct: 361 AKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGA 420
Query: 420 VREDTYPVGTQGVPSLALAQGGPQGSWRFLEWKSMPRLPTDLDIGGPWFPHYDFEWSCWV 479
VREDTYPVGTQGVPS ALAQGGPQGSWRFL+W SMPRLPTDLD+ GPWF HYDF SCWV
Sbjct: 421 VREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWV 480
Query: 480 RAISQEDQLATCWQAEHCGE 499
RAISQEDQLA CWQAEH E
Sbjct: 481 RAISQEDQLAPCWQAEHPAE 500
>gi|14149985 TBC1 domain family, member 3F [Homo sapiens]
Length = 549
Score = 842 bits (2175), Expect = 0.0
Identities = 405/500 (81%), Positives = 439/500 (87%), Gaps = 1/500 (0%)
Query: 1 MDMVENADSLQAQERKDILMKYDKGHRAGLPEDKGPEPV-GINSSIDRFGILHETELPPV 59
MD+VE A S AQER+DI+MKY+KGHRAGLPEDKGP+P N+++D GI+HETELPP+
Sbjct: 1 MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL 60
Query: 60 TAREAKKIRREMTRTSKWMEMLGEWETYKHSSKLIDRVYKGIPMNIRGPVWSVLLNIQEI 119
TAREAK+IRRE++R SKW++MLG+WE YK S KLIDR YKG+PMNIRGP+WSVLLN +E+
Sbjct: 61 TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNTEEM 120
Query: 120 KLKNPGRYQIMKERGKRSSEHIHHIDLDVRTTLRNHVFFRDRYGAKQRELFYILLAYSEY 179
KLKNPGRYQIMKE+GK+SSEHI ID DV TLR H+FFRDRYG KQREL +ILLAY EY
Sbjct: 121 KLKNPGRYQIMKEKGKKSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEY 180
Query: 180 NPEVGYCRDLSHITALFLLYLPEEDAFWALVQLLASERHSLPGFHSPNGGTVQGLQDQQE 239
NPEVGYCRDLSHI ALFLLYLPEEDAFWALVQLLASERHSL GFHSPNGGTVQGLQDQQE
Sbjct: 181 NPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQE 240
Query: 240 HVVPKSQPKTMWHQDKEGLCGQCASLGCLLRNLIDGISLGLTLRLWDVYLVEGEQVLMPI 299
HVV SQPKTM HQDK+ LCGQC+ LGCL+R LIDGISLGLTLRLWDVYLVEGEQ LMPI
Sbjct: 241 HVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPI 300
Query: 300 TSIALKVQQKRLMKTSRCGLWARLRNQFFDTWAMNDDTVLKHLRASTKKLTRKQGDLPPP 359
T IA KVQQKRL KTSRCG WAR N+F DTWA ++DTVLKHLRAS KKLTRK+GDLPPP
Sbjct: 301 TRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKKGDLPPP 360
Query: 360 AKREQGSLAPRPVPASRGGKTLCKGYRQAPPGPPAQFQRPICSASPPWASRFSTPCPGGA 419
AK EQGS A RPVPASRGGKTLCKG RQAPPGPPA+F RPI SASPP A R STPCPGGA
Sbjct: 361 AKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGA 420
Query: 420 VREDTYPVGTQGVPSLALAQGGPQGSWRFLEWKSMPRLPTDLDIGGPWFPHYDFEWSCWV 479
VREDTYPVGTQGVPS ALAQGGPQGSWRFL+W SMPRLPTDLD+ GPWF HYDF SCWV
Sbjct: 421 VREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWV 480
Query: 480 RAISQEDQLATCWQAEHCGE 499
RAISQEDQLA CWQAEH E
Sbjct: 481 RAISQEDQLAPCWQAEHPAE 500
>gi|149999613 TBC1 domain family, member 3B [Homo sapiens]
Length = 549
Score = 841 bits (2172), Expect = 0.0
Identities = 405/500 (81%), Positives = 438/500 (87%), Gaps = 1/500 (0%)
Query: 1 MDMVENADSLQAQERKDILMKYDKGHRAGLPEDKGPEPV-GINSSIDRFGILHETELPPV 59
MD+VE A S AQER+DI+MKY+KGHRAGLPEDKGP+P N+++D GI+HETELPP+
Sbjct: 1 MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL 60
Query: 60 TAREAKKIRREMTRTSKWMEMLGEWETYKHSSKLIDRVYKGIPMNIRGPVWSVLLNIQEI 119
TAREAK+IRRE++R SKW++MLG+WE YK S KLIDR YKG+PMNIRGP+WSVLLNI+E+
Sbjct: 61 TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEM 120
Query: 120 KLKNPGRYQIMKERGKRSSEHIHHIDLDVRTTLRNHVFFRDRYGAKQRELFYILLAYSEY 179
KLKNPGRYQIMKE+GKRSSEHI ID D+ TLR H+FFRDRYG KQREL +ILLAY EY
Sbjct: 121 KLKNPGRYQIMKEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEY 180
Query: 180 NPEVGYCRDLSHITALFLLYLPEEDAFWALVQLLASERHSLPGFHSPNGGTVQGLQDQQE 239
NPEVGYCRDLSHI ALFLLY PEEDAFWALVQLLASERHSL GFHSPNGGTVQGLQDQQE
Sbjct: 181 NPEVGYCRDLSHIAALFLLYFPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQE 240
Query: 240 HVVPKSQPKTMWHQDKEGLCGQCASLGCLLRNLIDGISLGLTLRLWDVYLVEGEQVLMPI 299
HVV SQ KTM HQDK+ LCGQC+ LGCL+R LIDGISLGLTLRLWDVYLVEGEQ LMPI
Sbjct: 241 HVVATSQSKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPI 300
Query: 300 TSIALKVQQKRLMKTSRCGLWARLRNQFFDTWAMNDDTVLKHLRASTKKLTRKQGDLPPP 359
T IA KVQQKRL KTSRCG WAR N+F DTWA ++DTVLKHLRAS KKLTRKQGDLPPP
Sbjct: 301 TRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPP 360
Query: 360 AKREQGSLAPRPVPASRGGKTLCKGYRQAPPGPPAQFQRPICSASPPWASRFSTPCPGGA 419
AK EQGS A RPVPASRGGKTLCKG RQAPPGPPA+F RPI SASPP A R STPCPGGA
Sbjct: 361 AKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGA 420
Query: 420 VREDTYPVGTQGVPSLALAQGGPQGSWRFLEWKSMPRLPTDLDIGGPWFPHYDFEWSCWV 479
VREDTYPVGTQGVPS ALAQGGPQGSWRFL+W SMPRLPTDLD+ GPWF HYDF SCWV
Sbjct: 421 VREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWV 480
Query: 480 RAISQEDQLATCWQAEHCGE 499
RAISQEDQLA CWQAEH E
Sbjct: 481 RAISQEDQLAPCWQAEHPAE 500
>gi|239756926 PREDICTED: similar to TBC1 domain family, member 3
[Homo sapiens]
Length = 424
Score = 332 bits (851), Expect = 2e-90
Identities = 165/221 (74%), Positives = 174/221 (78%), Gaps = 2/221 (0%)
Query: 309 KRLMKTSRCGLWARLRNQFFDTWAMNDDTVLKHLRASTKKLTRKQGDLPPPAKREQGSLA 368
KRL KTSRCG WAR N+F D WA +DDTVLKHLRAS KKLTRKQGDLPPPAK EQGS A
Sbjct: 185 KRLTKTSRCGPWARFWNRFVDAWARDDDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSA 244
Query: 369 PRPVPASRGGKTLCKGYRQAPPGPPAQFQRPICSASPPWASRFSTPCPGGAVREDTYPVG 428
RPVPASRGGKTLCKG RQAPPGPPA+F PI SASPP A R STPCPGGAVREDTYPVG
Sbjct: 245 SRPVPASRGGKTLCKGDRQAPPGPPARFPWPIWSASPPRAPRSSTPCPGGAVREDTYPVG 304
Query: 429 TQGVPSLALAQGGPQGSWRFLEWKSMPRLPTDLDIGGPWFPHYDFEWSCWVRAISQEDQL 488
TQGVPS ALAQGGPQGSWRFL+W SMPRLPTDLD+G PWF YDF SCWVRAISQEDQ
Sbjct: 305 TQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVGDPWFRRYDFRQSCWVRAISQEDQP 364
Query: 489 ATCWQAEHCGEVHNKDMSWPEEMS--FTANSSKIDRQKVPT 527
ATCWQAEH E S P S T ++ ++Q PT
Sbjct: 365 ATCWQAEHPAERVRSAFSAPSTDSDQGTPFRARDEQQCAPT 405
Score = 261 bits (666), Expect = 4e-69
Identities = 123/164 (75%), Positives = 145/164 (88%), Gaps = 1/164 (0%)
Query: 1 MDMVENADSLQAQERKDILMKYDKGHRAGLPEDKGPEPVG-INSSIDRFGILHETELPPV 59
MD+VE S AQER+DI+MKY+KGHRAGLPEDKGP+P G N++ID FG+ HETELPP+
Sbjct: 1 MDVVEVVGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFGSYNNNIDHFGMQHETELPPL 60
Query: 60 TAREAKKIRREMTRTSKWMEMLGEWETYKHSSKLIDRVYKGIPMNIRGPVWSVLLNIQEI 119
TARE K+IRRE++R SKW++MLGEW+TYK+S KLIDR Y+GIPMNIRGP+WSVLLNI+EI
Sbjct: 61 TAREVKQIRREISRKSKWVKMLGEWDTYKNSRKLIDRAYQGIPMNIRGPMWSVLLNIEEI 120
Query: 120 KLKNPGRYQIMKERGKRSSEHIHHIDLDVRTTLRNHVFFRDRYG 163
KLKNPGRYQIMKE+GKRSSEHI +DLDV TLR H+FFRDRYG
Sbjct: 121 KLKNPGRYQIMKEKGKRSSEHIQQMDLDVSGTLRRHIFFRDRYG 164
>gi|14149627 ubiquitin specific peptidase 15 [Homo sapiens]
Length = 952
Score = 266 bits (679), Expect = 1e-70
Identities = 138/323 (42%), Positives = 204/323 (63%), Gaps = 7/323 (2%)
Query: 479 VRAISQEDQLATCWQAEHCGEVHNKDMSWPEEMSFTA--NSSKIDRQKVPTEKGATGLSN 536
V I Q+++ T + V N + P S+TA N + + + G GLSN
Sbjct: 208 VLVIEQKNEDGTWPRGPSTPNVKNSNYCLP---SYTAYKNYDYSEPGRNNEQPGLCGLSN 264
Query: 537 LGNTCFMNSSIQCVSNTQPLTQYFISGRHLYELNRTNPIGMKGHMAKCYGDLVQELWSGT 596
LGNTCFMNS+IQC+SNT PLT+YF++ ++ ELN NP+GM+G +AK Y +L++++WSG
Sbjct: 265 LGNTCFMNSAIQCLSNTPPLTEYFLNDKYQEELNFDNPLGMRGEIAKSYAELIKQMWSGK 324
Query: 597 QKSVAPLKLRRTIAKYAPKFDGFQQQDSQELLAFLLDGLHEDLNRVHEKPYVELKDSDGR 656
V P + + ++AP+F G+QQQD QELLAFLLDGLHEDLNR+ +KPY++LKD+DGR
Sbjct: 325 FSYVTPRAFKTQVGRFAPQFSGYQQQDCQELLAFLLDGLHEDLNRIRKKPYIQLKDADGR 384
Query: 657 PDWEVAAEAWDNHLRRNRSIIVDLFHGQLRSQVKCKTCGHISVRFDPFNFLSLPLPMDSY 716
PD VA EAW+NHL+RN SIIVD+FHG +S + C C ISV FDPF +L+LPLPM
Sbjct: 385 PDKVVAEEAWENHLKRNDSIIVDIFHGLFKSTLVCPECAKISVTFDPFCYLTLPLPMKKE 444
Query: 717 MDLEITVIKLDG-TTPVRYGLRLNMDEKYTGLKKQLRDLCGLNSEQILLAEVHDSNI-KN 774
LE+ ++++D T P++Y + + L L L G+ ++++++ ++++ +
Sbjct: 445 RTLEVYLVRMDPLTKPMQYKVVVPKIGNILDLCTALSALSGIPADKMIVTDIYNHRFHRI 504
Query: 775 FPQDNQKVQLSVSGFLCAFEIPV 797
F D + + FEI +
Sbjct: 505 FAMDENLSSIMERDDIYVFEINI 527
Score = 94.7 bits (234), Expect = 5e-19
Identities = 48/131 (36%), Positives = 72/131 (54%), Gaps = 3/131 (2%)
Query: 991 AYIAVDWHPTALHLRYQTSQERVVDKHESVEQSRRAQAEP-INLDSCLRAFTSEEELGES 1049
+++A+DW P + + +KHESVE + +P + L C+ FT++E+LG
Sbjct: 718 SFLALDWDPDLKKRYFDENAAEDFEKHESVEY--KPPKKPFVKLKDCIELFTTKEKLGAE 775
Query: 1050 EMYYCSKCKTHCLATKKLDLWRLPPFLIIHLKRFQFVNDQWIKSQKIVRFLRESFDPSAF 1109
+ +YC CK H ATKKLDLW LPP L++HLKRF + K +V F D S F
Sbjct: 776 DPWYCPNCKEHQQATKKLDLWSLPPVLVVHLKRFSYSRYMRDKLDTLVDFPINDLDMSEF 835
Query: 1110 LVPRDPALCQH 1120
L+ + C++
Sbjct: 836 LINPNAGPCRY 846
Score = 62.0 bits (149), Expect = 4e-09
Identities = 33/88 (37%), Positives = 50/88 (56%), Gaps = 1/88 (1%)
Query: 1312 YNLYAISCHSGILSGGHYITYAKN-PNCKWYCYNDSSCEELHPDEIDTDSAYILFYEQQG 1370
YNL A+S H G + GGHY +AKN + KWY ++DSS D+I + +AY+LFY++Q
Sbjct: 846 YNLIAVSNHYGGMGGGHYTAFAKNKDDGKWYYFDDSSVSTASEDQIVSKAAYVLFYQRQD 905
Query: 1371 IDYAQFLPKIDGKKMADTSSTDEDSESD 1398
+D + +++T ESD
Sbjct: 906 TFSGTGFFPLDRETKGASAATGIPLESD 933
>gi|7661864 USP6 N-terminal like isoform 1 [Homo sapiens]
Length = 828
Score = 264 bits (675), Expect = 4e-70
Identities = 154/429 (35%), Positives = 221/429 (51%), Gaps = 16/429 (3%)
Query: 12 AQERKDILMKYDKGHRAGLPEDKGPEPVGINSSIDRFGILHETELPPVTAREAKKIRREM 71
AQER +I+ KYD+G E + DRFG LHE ELP ++ E+
Sbjct: 12 AQERAEIVAKYDRGREGAEIEPWEDADYLVYKVTDRFGFLHEEELPDHNVAVERQKHLEI 71
Query: 72 TRTSKWMEMLGEWETYKHSSKLIDRVYKGIPMNIRGPVWSVLLNIQEIKLKNPGRYQIMK 131
RT+KW++ML WE YK++ K R+YKGIP+ +RG VW++LL I ++K + Y +K
Sbjct: 72 ERTTKWLKMLKGWEKYKNTEKFHRRIYKGIPLQLRGEVWALLLEIPKMKEETRDLYSKLK 131
Query: 132 ERGKRSSEHIHHIDLDVRTTLRNHVFFRDRYGAKQRELFYILLAYSEYNPEVGYCRDLSH 191
R + S I IDLDV T R+H+ FRDRYG KQ+ LF++L AYS YN EVGYC+ +S
Sbjct: 132 HRARGCSPDIRQIDLDVNRTFRDHIMFRDRYGVKQQSLFHVLAAYSIYNTEVGYCQGMSQ 191
Query: 192 ITALFLLYLPEEDAFWALVQLLASERHSLPGFHSPNGGTVQGLQDQQEHVVPKSQPKTMW 251
ITAL L+Y+ EEDAFWALV+L + +H++ GF + Q+ E ++ K K
Sbjct: 192 ITALLLMYMNEEDAFWALVKLFSGPKHAMHGFFVQGFPKLLRFQEHHEKILNKFLSKLKQ 251
Query: 252 HQDKEGLCGQCASLGCLLRNLIDGISLGLTLRLWDVYLVEGEQVLMPITSIALKVQQKRL 311
H D + + ++ + +D L LR+WD+Y+ EGE+VL ++ LK+ +K L
Sbjct: 252 HLDSQEIYTSFYTMKWFFQCFLDRTPFTLNLRIWDIYIFEGERVLTAMSYTILKLHKKHL 311
Query: 312 MKTSRCGLWARLRNQFFDTWAMNDDTVLKHLRASTKKLTRKQGDLPPPAKREQGSLAP-- 369
MK S L + + DD V++ L+ S +L R + DLP P K ++ P
Sbjct: 312 MKLSMEELVEFFQETLAKDFFFEDDFVIEQLQISMTELKRAKLDLPEPGKEDEYPKKPLG 371
Query: 370 --RPVPASRGGKTLCKGYRQAPPGPPAQFQRPICSASPPWASRFSTPCPGGAVREDTYPV 427
P S G L G QR + SP + R + P +P
Sbjct: 372 QLPPELQSWGVHHLSNG------------QRSVGRPSPLASGRRESGAPHRRHEHSPHPQ 419
Query: 428 GTQGVPSLA 436
G P A
Sbjct: 420 SRTGTPERA 428
>gi|122937432 USP6 N-terminal like isoform 2 [Homo sapiens]
Length = 845
Score = 264 bits (675), Expect = 4e-70
Identities = 154/429 (35%), Positives = 221/429 (51%), Gaps = 16/429 (3%)
Query: 12 AQERKDILMKYDKGHRAGLPEDKGPEPVGINSSIDRFGILHETELPPVTAREAKKIRREM 71
AQER +I+ KYD+G E + DRFG LHE ELP ++ E+
Sbjct: 29 AQERAEIVAKYDRGREGAEIEPWEDADYLVYKVTDRFGFLHEEELPDHNVAVERQKHLEI 88
Query: 72 TRTSKWMEMLGEWETYKHSSKLIDRVYKGIPMNIRGPVWSVLLNIQEIKLKNPGRYQIMK 131
RT+KW++ML WE YK++ K R+YKGIP+ +RG VW++LL I ++K + Y +K
Sbjct: 89 ERTTKWLKMLKGWEKYKNTEKFHRRIYKGIPLQLRGEVWALLLEIPKMKEETRDLYSKLK 148
Query: 132 ERGKRSSEHIHHIDLDVRTTLRNHVFFRDRYGAKQRELFYILLAYSEYNPEVGYCRDLSH 191
R + S I IDLDV T R+H+ FRDRYG KQ+ LF++L AYS YN EVGYC+ +S
Sbjct: 149 HRARGCSPDIRQIDLDVNRTFRDHIMFRDRYGVKQQSLFHVLAAYSIYNTEVGYCQGMSQ 208
Query: 192 ITALFLLYLPEEDAFWALVQLLASERHSLPGFHSPNGGTVQGLQDQQEHVVPKSQPKTMW 251
ITAL L+Y+ EEDAFWALV+L + +H++ GF + Q+ E ++ K K
Sbjct: 209 ITALLLMYMNEEDAFWALVKLFSGPKHAMHGFFVQGFPKLLRFQEHHEKILNKFLSKLKQ 268
Query: 252 HQDKEGLCGQCASLGCLLRNLIDGISLGLTLRLWDVYLVEGEQVLMPITSIALKVQQKRL 311
H D + + ++ + +D L LR+WD+Y+ EGE+VL ++ LK+ +K L
Sbjct: 269 HLDSQEIYTSFYTMKWFFQCFLDRTPFTLNLRIWDIYIFEGERVLTAMSYTILKLHKKHL 328
Query: 312 MKTSRCGLWARLRNQFFDTWAMNDDTVLKHLRASTKKLTRKQGDLPPPAKREQGSLAP-- 369
MK S L + + DD V++ L+ S +L R + DLP P K ++ P
Sbjct: 329 MKLSMEELVEFFQETLAKDFFFEDDFVIEQLQISMTELKRAKLDLPEPGKEDEYPKKPLG 388
Query: 370 --RPVPASRGGKTLCKGYRQAPPGPPAQFQRPICSASPPWASRFSTPCPGGAVREDTYPV 427
P S G L G QR + SP + R + P +P
Sbjct: 389 QLPPELQSWGVHHLSNG------------QRSVGRPSPLASGRRESGAPHRRHEHSPHPQ 436
Query: 428 GTQGVPSLA 436
G P A
Sbjct: 437 SRTGTPERA 445
>gi|40795667 ubiquitin specific protease 4 isoform b [Homo sapiens]
Length = 916
Score = 262 bits (669), Expect = 2e-69
Identities = 127/278 (45%), Positives = 185/278 (66%), Gaps = 7/278 (2%)
Query: 499 EVHNKDMSWPEEM------SFTANSSKIDRQKVPTEKGATGLSNLGNTCFMNSSIQCVSN 552
E N+D +WP + F+A+ + + + G GL NLGNTCFMNS++QC+SN
Sbjct: 216 EPQNEDGTWPRQTLQSNGSGFSASYNCQEPPSSHIQPGLCGLGNLGNTCFMNSALQCLSN 275
Query: 553 TQPLTQYFISGRHLYELNRTNPIGMKGHMAKCYGDLVQELWSGTQKSVAPLKLRRTIAKY 612
T PLT YF+ + E+NR NP+GMKG +A+ Y +L++++WSG VAP + + ++
Sbjct: 276 TAPLTDYFLKDEYEAEINRDNPLGMKGEIAEAYAELIKQMWSGRDAHVAPRMFKTQVGRF 335
Query: 613 APKFDGFQQQDSQELLAFLLDGLHEDLNRVHEKPYVELKDSDGRPDWEVAAEAWDNHLRR 672
AP+F G+QQQDSQELLAFLLDGLHEDLNRV +KPY+ELKD++GRPD VA EAW+NH R
Sbjct: 336 APQFSGYQQQDSQELLAFLLDGLHEDLNRVKKKPYLELKDANGRPDAVVAKEAWENHRLR 395
Query: 673 NRSIIVDLFHGQLRSQVKCKTCGHISVRFDPFNFLSLPLPMDSYMDLEITVIKLD-GTTP 731
N S+IVD FHG +S + C C +SV FDPF +L+LPLP+ +E+ ++ D P
Sbjct: 396 NDSVIVDTFHGLFKSTLVCPECAKVSVTFDPFCYLTLPLPLKKDRVMEVFLVPADPHCRP 455
Query: 732 VRYGLRLNMDEKYTGLKKQLRDLCGLNSEQILLAEVHD 769
+Y + + + + L + L L G+ +E +++A+V++
Sbjct: 456 TQYRVTVPLMGAVSDLCEALSRLSGIAAENMVVADVYN 493
Score = 87.8 bits (216), Expect = 7e-17
Identities = 44/119 (36%), Positives = 63/119 (52%), Gaps = 2/119 (1%)
Query: 993 IAVDWHPTALHLRYQTSQERVVDKHESVEQSRRAQAEPINLDSCLRAFTSEEELGESEMY 1052
+A+DW L Y + +KH S+ Q ++ + + L C+ FT+ E LGE + +
Sbjct: 691 LAMDWDSETRRLYYDEQESEAYEKHVSMLQPQKKKKTTVALRDCIELFTTMETLGEHDPW 750
Query: 1053 YCSKCKTHCLATKKLDLWRLPPFLIIHLKRFQFVNDQW-IKSQKIVRFLRESFDPSAFL 1110
YC CK H ATKK DLW LP L++HLKRF + N W K +V F + S F+
Sbjct: 751 YCPNCKKHQQATKKFDLWSLPKILVVHLKRFSY-NRYWRDKLDTVVEFPIRGLNMSEFV 808
Score = 61.2 bits (147), Expect = 7e-09
Identities = 30/90 (33%), Positives = 51/90 (56%), Gaps = 2/90 (2%)
Query: 1311 IYNLYAISCHSGILSGGHYITYAKNP-NCKWYCYNDSSCEELHPDEIDTDSAYILFYEQQ 1369
+Y+L A+S H G + GHY YAKN N KWY ++DS+ D+I T +AY+LFY+++
Sbjct: 817 VYDLIAVSNHYGAMGVGHYTAYAKNKLNGKWYYFDDSNVSLASEDQIVTKAAYVLFYQRR 876
Query: 1370 GIDYAQFLPKIDGKKMADTSSTDEDSESDY 1399
++ + P + +D + S+ +
Sbjct: 877 DDEFYK-TPSLSSSGSSDGGTRPSSSQQGF 905
>gi|40795665 ubiquitin specific protease 4 isoform a [Homo sapiens]
Length = 963
Score = 256 bits (654), Expect = 1e-67
Identities = 120/243 (49%), Positives = 171/243 (70%), Gaps = 1/243 (0%)
Query: 528 EKGATGLSNLGNTCFMNSSIQCVSNTQPLTQYFISGRHLYELNRTNPIGMKGHMAKCYGD 587
+ G GL NLGNTCFMNS++QC+SNT PLT YF+ + E+NR NP+GMKG +A+ Y +
Sbjct: 298 QPGLCGLGNLGNTCFMNSALQCLSNTAPLTDYFLKDEYEAEINRDNPLGMKGEIAEAYAE 357
Query: 588 LVQELWSGTQKSVAPLKLRRTIAKYAPKFDGFQQQDSQELLAFLLDGLHEDLNRVHEKPY 647
L++++WSG VAP + + ++AP+F G+QQQDSQELLAFLLDGLHEDLNRV +KPY
Sbjct: 358 LIKQMWSGRDAHVAPRMFKTQVGRFAPQFSGYQQQDSQELLAFLLDGLHEDLNRVKKKPY 417
Query: 648 VELKDSDGRPDWEVAAEAWDNHLRRNRSIIVDLFHGQLRSQVKCKTCGHISVRFDPFNFL 707
+ELKD++GRPD VA EAW+NH RN S+IVD FHG +S + C C +SV FDPF +L
Sbjct: 418 LELKDANGRPDAVVAKEAWENHRLRNDSVIVDTFHGLFKSTLVCPECAKVSVTFDPFCYL 477
Query: 708 SLPLPMDSYMDLEITVIKLD-GTTPVRYGLRLNMDEKYTGLKKQLRDLCGLNSEQILLAE 766
+LPLP+ +E+ ++ D P +Y + + + + L + L L G+ +E +++A+
Sbjct: 478 TLPLPLKKDRVMEVFLVPADPHCRPTQYRVTVPLMGAVSDLCEALSRLSGIAAENMVVAD 537
Query: 767 VHD 769
V++
Sbjct: 538 VYN 540
Score = 87.8 bits (216), Expect = 7e-17
Identities = 44/119 (36%), Positives = 63/119 (52%), Gaps = 2/119 (1%)
Query: 993 IAVDWHPTALHLRYQTSQERVVDKHESVEQSRRAQAEPINLDSCLRAFTSEEELGESEMY 1052
+A+DW L Y + +KH S+ Q ++ + + L C+ FT+ E LGE + +
Sbjct: 738 LAMDWDSETRRLYYDEQESEAYEKHVSMLQPQKKKKTTVALRDCIELFTTMETLGEHDPW 797
Query: 1053 YCSKCKTHCLATKKLDLWRLPPFLIIHLKRFQFVNDQW-IKSQKIVRFLRESFDPSAFL 1110
YC CK H ATKK DLW LP L++HLKRF + N W K +V F + S F+
Sbjct: 798 YCPNCKKHQQATKKFDLWSLPKILVVHLKRFSY-NRYWRDKLDTVVEFPIRGLNMSEFV 855
Score = 61.2 bits (147), Expect = 7e-09
Identities = 30/90 (33%), Positives = 51/90 (56%), Gaps = 2/90 (2%)
Query: 1311 IYNLYAISCHSGILSGGHYITYAKNP-NCKWYCYNDSSCEELHPDEIDTDSAYILFYEQQ 1369
+Y+L A+S H G + GHY YAKN N KWY ++DS+ D+I T +AY+LFY+++
Sbjct: 864 VYDLIAVSNHYGAMGVGHYTAYAKNKLNGKWYYFDDSNVSLASEDQIVTKAAYVLFYQRR 923
Query: 1370 GIDYAQFLPKIDGKKMADTSSTDEDSESDY 1399
++ + P + +D + S+ +
Sbjct: 924 DDEFYK-TPSLSSSGSSDGGTRPSSSQQGF 952
>gi|24234683 ubiquitin specific peptidase 11 [Homo sapiens]
Length = 963
Score = 251 bits (642), Expect = 3e-66
Identities = 127/271 (46%), Positives = 177/271 (65%), Gaps = 2/271 (0%)
Query: 499 EVHNKDMSWPEEMSFTANSSKIDRQK-VPTEKGATGLSNLGNTCFMNSSIQCVSNTQPLT 557
E KD +WP N++ + + + G GL+NLGNTCFMNS++QC+SN LT
Sbjct: 275 ETRKKDGTWPSAQLHVMNNNMSEEDEDFKGQPGICGLTNLGNTCFMNSALQCLSNVPQLT 334
Query: 558 QYFISGRHLYELNRTNPIGMKGHMAKCYGDLVQELWSGTQKSVAPLKLRRTIAKYAPKFD 617
+YF++ +L ELN NP+GMKG +A+ Y DLV++ WSG +S+ P + + +A +F
Sbjct: 335 EYFLNNCYLEELNFRNPLGMKGEIAEAYADLVKQAWSGHHRSIVPHVFKNKVGHFASQFL 394
Query: 618 GFQQQDSQELLAFLLDGLHEDLNRVHEKPYVELKDSDGRPDWEVAAEAWDNHLRRNRSII 677
G+QQ DSQELL+FLLDGLHEDLNRV +K YVEL D+ GRPD EVA EAW NH RRN S+I
Sbjct: 395 GYQQHDSQELLSFLLDGLHEDLNRVKKKEYVELCDAAGRPDQEVAQEAWQNHKRRNDSVI 454
Query: 678 VDLFHGQLRSQVKCKTCGHISVRFDPFNFLSLPLPMDSYMDLEITVIKLD-GTTPVRYGL 736
VD FHG +S + C CG++SV FDPF +LS+PLP+ LE+ I +D P ++ L
Sbjct: 455 VDTFHGLFKSTLVCPDCGNVSVTFDPFCYLSVPLPISHKRVLEVFFIPMDPRRKPEQHRL 514
Query: 737 RLNMDEKYTGLKKQLRDLCGLNSEQILLAEV 767
+ K + L L G++ E++++A+V
Sbjct: 515 VVPKKGKISDLCVALSKHTGISPERMMVADV 545
Score = 89.4 bits (220), Expect = 2e-17
Identities = 59/177 (33%), Positives = 76/177 (42%), Gaps = 25/177 (14%)
Query: 944 DNCMGY-QYP--------FTLRVVQKDGNSCAWCPQYRFCRGCKIDCGEDRAFIGNAYIA 994
DNC+G Q+P FTL+ V +G S YIA
Sbjct: 699 DNCLGTSQWPPRRRRKQLFTLQTVNSNGTSDRTT--------------SPEEVHAQPYIA 744
Query: 995 VDWHPTALHLRYQTSQERVVDKHESVEQSRRAQAEPINLDSCLRAFTSEEELGESEMYYC 1054
+DW P Y + KH+ V + P+ L C+ FT+ E L + +YC
Sbjct: 745 IDWEPEMKKRYYDEVEAEGYVKHDCVGYVMKKA--PVRLQECIELFTTVETLEKENPWYC 802
Query: 1055 SKCKTHCLATKKLDLWRLPPFLIIHLKRFQFVNDQWIKSQKIVRFLRESFDPSAFLV 1111
CK H LATKKLDLW LP LIIHLKRF + K +V F D S F++
Sbjct: 803 PSCKQHQLATKKLDLWMLPEILIIHLKRFSYTKFSREKLDTLVEFPIRDLDFSEFVI 859
Score = 53.1 bits (126), Expect = 2e-06
Identities = 22/61 (36%), Positives = 43/61 (70%), Gaps = 1/61 (1%)
Query: 1312 YNLYAISCHSGILSGGHYITYAKNPNC-KWYCYNDSSCEELHPDEIDTDSAYILFYEQQG 1370
Y+L A+S H G + GHY T+A N + +W+ ++D+S ++ ++I++ +AY+LFY++Q
Sbjct: 872 YDLIAVSNHYGGMRDGHYTTFACNKDSGQWHYFDDNSVSPVNENQIESKAAYVLFYQRQD 931
Query: 1371 I 1371
+
Sbjct: 932 V 932
>gi|148235002 TBC1 domain family, member 26 [Homo sapiens]
Length = 250
Score = 241 bits (616), Expect = 3e-63
Identities = 123/221 (55%), Positives = 158/221 (71%), Gaps = 1/221 (0%)
Query: 1 MDMVENADSLQAQERKDILM-KYDKGHRAGLPEDKGPEPVGINSSIDRFGILHETELPPV 59
M+M + +L AQ + +I++ KY++GHRAG D G E V + + GI+HE ELP V
Sbjct: 1 MEMDGDPYNLPAQGQGNIIITKYEQGHRAGAAVDLGHEQVDVRKYTNNLGIVHEMELPRV 60
Query: 60 TAREAKKIRREMTRTSKWMEMLGEWETYKHSSKLIDRVYKGIPMNIRGPVWSVLLNIQEI 119
+A E K+ R+E RT+KW +ML +W Y+ + KL RVYK IP+ +RG WS+LL+I I
Sbjct: 61 SALEVKQRRKESKRTNKWQKMLADWTKYRSTKKLSQRVYKVIPLAVRGRAWSLLLDIDRI 120
Query: 120 KLKNPGRYQIMKERGKRSSEHIHHIDLDVRTTLRNHVFFRDRYGAKQRELFYILLAYSEY 179
K +NPG+Y++MKE+GKRSS IH I LDV TL+ H+ F R+G KQ+EL IL+AYS Y
Sbjct: 121 KSQNPGKYKVMKEKGKRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAY 180
Query: 180 NPEVGYCRDLSHITALFLLYLPEEDAFWALVQLLASERHSL 220
NPEVGY RDLS ITA+ LL LPEEDAFWAL QLLA ERHSL
Sbjct: 181 NPEVGYHRDLSRITAILLLCLPEEDAFWALTQLLAGERHSL 221
>gi|57529246 ubiquitin thioesterase 19 [Homo sapiens]
Length = 1318
Score = 198 bits (504), Expect = 3e-50
Identities = 96/183 (52%), Positives = 120/183 (65%)
Query: 530 GATGLSNLGNTCFMNSSIQCVSNTQPLTQYFISGRHLYELNRTNPIGMKGHMAKCYGDLV 589
G TGL NLGNTCFMNS IQ +SNT+ L +F E+N NP+G G +A + L+
Sbjct: 495 GFTGLVNLGNTCFMNSVIQSLSNTRELRDFFHDRSFEAEINYNNPLGTGGRLAIGFAVLL 554
Query: 590 QELWSGTQKSVAPLKLRRTIAKYAPKFDGFQQQDSQELLAFLLDGLHEDLNRVHEKPYVE 649
+ LW GT + P KL+ +A A +F G+ Q D+QE +AFLLDGLHEDLNR+ KPY E
Sbjct: 555 RALWKGTHHAFQPSKLKAIVASKASQFTGYAQHDAQEFMAFLLDGLHEDLNRIQNKPYTE 614
Query: 650 LKDSDGRPDWEVAAEAWDNHLRRNRSIIVDLFHGQLRSQVKCKTCGHISVRFDPFNFLSL 709
DSDGRPD VA EAW H RN S IVDLF GQ +S++ C C +S+ FDPF +L +
Sbjct: 615 TVDSDGRPDEVVAEEAWQRHKMRNDSFIVDLFQGQYKSKLVCPVCAKVSITFDPFLYLPV 674
Query: 710 PLP 712
PLP
Sbjct: 675 PLP 677
Score = 68.6 bits (166), Expect = 4e-11
Identities = 38/87 (43%), Positives = 48/87 (55%), Gaps = 1/87 (1%)
Query: 1026 AQAEPINLDSCLRAFTSEEELGESEMYYCSKCKTHCLATKKLDLWRLPPFLIIHLKRFQF 1085
A+A LD CL FT E L E +YC +CK H A+K+L LWRLP LI+ LKRF F
Sbjct: 1053 ARAGHFTLDQCLNLFTRPEVLAPEEAWYCPQCKQHREASKQLLLWRLPNVLIVQLKRFSF 1112
Query: 1086 VNDQW-IKSQKIVRFLRESFDPSAFLV 1111
+ W K +V F + D S F +
Sbjct: 1113 RSFIWRDKINDLVEFPVRNLDLSKFCI 1139
Score = 46.6 bits (109), Expect = 2e-04
Identities = 23/68 (33%), Positives = 37/68 (54%), Gaps = 8/68 (11%)
Query: 1310 PIYNLYAISCHSGILSGGHYITYAKNPNCK--------WYCYNDSSCEELHPDEIDTDSA 1361
P Y+LYA+ H G + GGHY A+ PN + W ++DS+ + ++ T A
Sbjct: 1147 PSYDLYAVINHYGGMIGGHYTACARLPNDRSSQRSDVGWRLFDDSTVTTVDESQVVTRYA 1206
Query: 1362 YILFYEQQ 1369
Y+LFY ++
Sbjct: 1207 YVLFYRRR 1214
>gi|239751420 PREDICTED: similar to hCG2039376 [Homo sapiens]
Length = 858
Score = 192 bits (488), Expect = 2e-48
Identities = 92/104 (88%), Positives = 96/104 (92%)
Query: 503 KDMSWPEEMSFTANSSKIDRQKVPTEKGATGLSNLGNTCFMNSSIQCVSNTQPLTQYFIS 562
K S E++ + NSSKIDR KVPTEKGATGLSNLGNTCFMNSSIQCVSNTQPLTQYFIS
Sbjct: 750 KKSSVAEDIGYETNSSKIDRHKVPTEKGATGLSNLGNTCFMNSSIQCVSNTQPLTQYFIS 809
Query: 563 GRHLYELNRTNPIGMKGHMAKCYGDLVQELWSGTQKSVAPLKLR 606
GRHLYELNRTNPIGMKGHMAKCYGDLVQELWSGTQK+VAPLKLR
Sbjct: 810 GRHLYELNRTNPIGMKGHMAKCYGDLVQELWSGTQKNVAPLKLR 853
>gi|239745813 PREDICTED: hypothetical protein XP_002343595 [Homo
sapiens]
Length = 279
Score = 186 bits (472), Expect = 1e-46
Identities = 104/209 (49%), Positives = 124/209 (59%), Gaps = 22/209 (10%)
Query: 278 LGLTLRLWDVYLVEGEQVLMPITSIALKVQQKRLMKTSRCGLWARLRNQFFDTWAMNDDT 337
+GL R + G PI + K LMK SR GLWAR ++QF TWA++ D
Sbjct: 79 VGLPRRRSGLVSRAGHSDAEPIPHVTQMKVGKHLMKASRSGLWARFQDQFPQTWALDSDA 138
Query: 338 VLKHLRASTKKLTRKQGDLPPPAKREQGSLAPRPVPASR-GGKTLCKGYRQAPPGPPAQF 396
VL+HL+AS +K +QGS APRP AS G KTLCKG RQAPPGP A F
Sbjct: 139 VLRHLQASVL------------SKPKQGSSAPRPELASPCGRKTLCKGSRQAPPGPQAHF 186
Query: 397 QRPICSASPPWASRFSTPCPGGAVREDTYPVG-TQGVPSLALAQGGPQGSWRFLEWKSMP 455
Q+ I SASPPW TPCP VG +QGVP LA AQGGP+ SWR+L+W S+P
Sbjct: 187 QQCIWSASPPWVPLPFTPCP--------VLVGLSQGVPRLAPAQGGPRVSWRYLQWNSLP 238
Query: 456 RLPTDLDIGGPWFPHYDFEWSCWVRAISQ 484
+LP D D+ PWFPHYDFE CW R S+
Sbjct: 239 QLPMDSDVVSPWFPHYDFEQGCWARVPSK 267
>gi|239756790 PREDICTED: similar to hCG1991532 [Homo sapiens]
Length = 167
Score = 181 bits (460), Expect = 3e-45
Identities = 96/175 (54%), Positives = 113/175 (64%), Gaps = 22/175 (12%)
Query: 312 MKTSRCGLWARLRNQFFDTWAMNDDTVLKHLRASTKKLTRKQGDLPPPAKREQGSLAPRP 371
MK SR GLWAR ++QF TWA++ D VL+HL+AS +K +QGS APRP
Sbjct: 1 MKASRSGLWARFQDQFPQTWALDSDAVLRHLQASVL------------SKPKQGSSAPRP 48
Query: 372 VPASR-GGKTLCKGYRQAPPGPPAQFQRPICSASPPWASRFSTPCPGGAVREDTYPVG-T 429
AS G KTLCKG RQAPPGP A FQ+ I SASPPW TPCP VG +
Sbjct: 49 ELASPCGRKTLCKGSRQAPPGPQAHFQQRIWSASPPWVPLPFTPCP--------VLVGLS 100
Query: 430 QGVPSLALAQGGPQGSWRFLEWKSMPRLPTDLDIGGPWFPHYDFEWSCWVRAISQ 484
QGVP LA AQGGP+ SWR+L+W S+P+LP D D+ PWFPHYDFE CW R S+
Sbjct: 101 QGVPRLAPAQGGPRVSWRYLQWNSLPQLPMDSDVVSPWFPHYDFEQGCWARVPSK 155
>gi|151108489 TBC1 domain family, member 28 [Homo sapiens]
Length = 210
Score = 179 bits (453), Expect = 2e-44
Identities = 91/182 (50%), Positives = 126/182 (69%), Gaps = 1/182 (0%)
Query: 1 MDMVENADSLQAQERKDILM-KYDKGHRAGLPEDKGPEPVGINSSIDRFGILHETELPPV 59
M+M E+ D+L AQ + +I++ KY++GHRAG D G E V + + GI+HE ELP V
Sbjct: 1 MEMDEDPDNLPAQGQGNIIITKYEQGHRAGAAVDLGHEQVDVRKYTNNLGIVHEMELPRV 60
Query: 60 TAREAKKIRREMTRTSKWMEMLGEWETYKHSSKLIDRVYKGIPMNIRGPVWSVLLNIQEI 119
+A E K+ R+E RT+KW +ML +W Y+ + KL RV K IP+ +RG S+LL+I +I
Sbjct: 61 SALEVKQRRKESKRTNKWQKMLADWTKYRSTKKLSQRVCKVIPLAVRGRALSLLLDIDKI 120
Query: 120 KLKNPGRYQIMKERGKRSSEHIHHIDLDVRTTLRNHVFFRDRYGAKQRELFYILLAYSEY 179
K +NPG+Y++MKE+GKRSS IH I LDV TL+ H+ F R+G KQ+EL IL+AYS Y
Sbjct: 121 KSQNPGKYKVMKEKGKRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAY 180
Query: 180 NP 181
NP
Sbjct: 181 NP 182
>gi|239756750 PREDICTED: similar to TBC1 domain family, member 28
[Homo sapiens]
Length = 234
Score = 172 bits (437), Expect = 2e-42
Identities = 89/182 (48%), Positives = 124/182 (68%), Gaps = 1/182 (0%)
Query: 1 MDMVENADSLQAQERKDILM-KYDKGHRAGLPEDKGPEPVGINSSIDRFGILHETELPPV 59
M+M + +L AQ + +I++ KY++GHRAG D G E V + + GI+HE ELP V
Sbjct: 25 MEMDGDPYNLPAQGQGNIIITKYEQGHRAGAAVDLGHEQVDVRKYTNNLGIVHEMELPHV 84
Query: 60 TAREAKKIRREMTRTSKWMEMLGEWETYKHSSKLIDRVYKGIPMNIRGPVWSVLLNIQEI 119
+A E K+ R+E RT+KW +ML +W Y+ + KL RV K IP+ +RG S+LL+I +I
Sbjct: 85 SALEVKQRRKESKRTNKWQKMLADWTKYRSTKKLSQRVCKVIPLAVRGRALSLLLDIDKI 144
Query: 120 KLKNPGRYQIMKERGKRSSEHIHHIDLDVRTTLRNHVFFRDRYGAKQRELFYILLAYSEY 179
K +NPG+Y++MKE+GKRSS IH I LDV TL+ H+ F R+G KQ+EL IL+AYS Y
Sbjct: 145 KSQNPGKYKVMKEKGKRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAY 204
Query: 180 NP 181
NP
Sbjct: 205 NP 206
>gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens]
Length = 1118
Score = 167 bits (424), Expect = 5e-41
Identities = 91/223 (40%), Positives = 133/223 (59%), Gaps = 5/223 (2%)
Query: 502 NKDMSWPEEMSFTANSSKIDRQKVPTEKGA----TGLSNLGNTCFMNSSIQCVSNTQPLT 557
NK +P+ ++S+I R P G+ TGL NLGNTC+MNS +QC+ N L
Sbjct: 744 NKPTCYPKAEISRLSASQI-RNLNPVFGGSGPALTGLRNLGNTCYMNSILQCLCNAPHLA 802
Query: 558 QYFISGRHLYELNRTNPIGMKGHMAKCYGDLVQELWSGTQKSVAPLKLRRTIAKYAPKFD 617
YF + ++NR+N +G KG +A+ +G +++ LW+G + ++P + TI K +F
Sbjct: 803 DYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMKALWTGQYRYISPKDFKITIGKINDQFA 862
Query: 618 GFQQQDSQELLAFLLDGLHEDLNRVHEKPYVELKDSDGRPDWEVAAEAWDNHLRRNRSII 677
G+ QQDSQELL FL+DGLHEDLN+ + + +++D D++ A AW H + N SII
Sbjct: 863 GYSQQDSQELLLFLMDGLHEDLNKADNRKRYKEENNDHLDDFKAAEHAWQKHKQLNESII 922
Query: 678 VDLFHGQLRSQVKCKTCGHISVRFDPFNFLSLPLPMDSYMDLE 720
V LF GQ +S V+C TC S F+ F +LSLPL S L+
Sbjct: 923 VALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPLASTSKCTLQ 965
Score = 70.5 bits (171), Expect = 1e-11
Identities = 32/86 (37%), Positives = 50/86 (58%)
Query: 1026 AQAEPINLDSCLRAFTSEEELGESEMYYCSKCKTHCLATKKLDLWRLPPFLIIHLKRFQF 1085
A L CLR F+ EE+L ++ +YCS C+ + KK+++W+LPP L++HLKRF +
Sbjct: 957 ASTSKCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSY 1016
Query: 1086 VNDQWIKSQKIVRFLRESFDPSAFLV 1111
K Q V F E+ D S +++
Sbjct: 1017 DGRWKQKLQTSVDFPLENLDLSQYVI 1042
Score = 53.1 bits (126), Expect = 2e-06
Identities = 23/60 (38%), Positives = 35/60 (58%), Gaps = 1/60 (1%)
Query: 1312 YNLYAISCHSGILSGGHYITYAKN-PNCKWYCYNDSSCEELHPDEIDTDSAYILFYEQQG 1370
YNL+++S H G L GGHY Y KN +W+ ++D ++ + + +AYILFY G
Sbjct: 1051 YNLFSVSNHYGGLDGGHYTAYCKNAARQRWFKFDDHEVSDISVSSVKSSAAYILFYTSLG 1110
>gi|190684692 ubiquitin specific peptidase 8 [Homo sapiens]
Length = 1118
Score = 167 bits (424), Expect = 5e-41
Identities = 91/223 (40%), Positives = 133/223 (59%), Gaps = 5/223 (2%)
Query: 502 NKDMSWPEEMSFTANSSKIDRQKVPTEKGA----TGLSNLGNTCFMNSSIQCVSNTQPLT 557
NK +P+ ++S+I R P G+ TGL NLGNTC+MNS +QC+ N L
Sbjct: 744 NKPTCYPKAEISRLSASQI-RNLNPVFGGSGPALTGLRNLGNTCYMNSILQCLCNAPHLA 802
Query: 558 QYFISGRHLYELNRTNPIGMKGHMAKCYGDLVQELWSGTQKSVAPLKLRRTIAKYAPKFD 617
YF + ++NR+N +G KG +A+ +G +++ LW+G + ++P + TI K +F
Sbjct: 803 DYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMKALWTGQYRYISPKDFKITIGKINDQFA 862
Query: 618 GFQQQDSQELLAFLLDGLHEDLNRVHEKPYVELKDSDGRPDWEVAAEAWDNHLRRNRSII 677
G+ QQDSQELL FL+DGLHEDLN+ + + +++D D++ A AW H + N SII
Sbjct: 863 GYSQQDSQELLLFLMDGLHEDLNKADNRKRYKEENNDHLDDFKAAEHAWQKHKQLNESII 922
Query: 678 VDLFHGQLRSQVKCKTCGHISVRFDPFNFLSLPLPMDSYMDLE 720
V LF GQ +S V+C TC S F+ F +LSLPL S L+
Sbjct: 923 VALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPLASTSKCTLQ 965
Score = 70.5 bits (171), Expect = 1e-11
Identities = 32/86 (37%), Positives = 50/86 (58%)
Query: 1026 AQAEPINLDSCLRAFTSEEELGESEMYYCSKCKTHCLATKKLDLWRLPPFLIIHLKRFQF 1085
A L CLR F+ EE+L ++ +YCS C+ + KK+++W+LPP L++HLKRF +
Sbjct: 957 ASTSKCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSY 1016
Query: 1086 VNDQWIKSQKIVRFLRESFDPSAFLV 1111
K Q V F E+ D S +++
Sbjct: 1017 DGRWKQKLQTSVDFPLENLDLSQYVI 1042
Score = 53.1 bits (126), Expect = 2e-06
Identities = 23/60 (38%), Positives = 35/60 (58%), Gaps = 1/60 (1%)
Query: 1312 YNLYAISCHSGILSGGHYITYAKN-PNCKWYCYNDSSCEELHPDEIDTDSAYILFYEQQG 1370
YNL+++S H G L GGHY Y KN +W+ ++D ++ + + +AYILFY G
Sbjct: 1051 YNLFSVSNHYGGLDGGHYTAYCKNAARQRWFKFDDHEVSDISVSSVKSSAAYILFYTSLG 1110
>gi|190684690 ubiquitin specific peptidase 8 [Homo sapiens]
Length = 1118
Score = 167 bits (424), Expect = 5e-41
Identities = 91/223 (40%), Positives = 133/223 (59%), Gaps = 5/223 (2%)
Query: 502 NKDMSWPEEMSFTANSSKIDRQKVPTEKGA----TGLSNLGNTCFMNSSIQCVSNTQPLT 557
NK +P+ ++S+I R P G+ TGL NLGNTC+MNS +QC+ N L
Sbjct: 744 NKPTCYPKAEISRLSASQI-RNLNPVFGGSGPALTGLRNLGNTCYMNSILQCLCNAPHLA 802
Query: 558 QYFISGRHLYELNRTNPIGMKGHMAKCYGDLVQELWSGTQKSVAPLKLRRTIAKYAPKFD 617
YF + ++NR+N +G KG +A+ +G +++ LW+G + ++P + TI K +F
Sbjct: 803 DYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMKALWTGQYRYISPKDFKITIGKINDQFA 862
Query: 618 GFQQQDSQELLAFLLDGLHEDLNRVHEKPYVELKDSDGRPDWEVAAEAWDNHLRRNRSII 677
G+ QQDSQELL FL+DGLHEDLN+ + + +++D D++ A AW H + N SII
Sbjct: 863 GYSQQDSQELLLFLMDGLHEDLNKADNRKRYKEENNDHLDDFKAAEHAWQKHKQLNESII 922
Query: 678 VDLFHGQLRSQVKCKTCGHISVRFDPFNFLSLPLPMDSYMDLE 720
V LF GQ +S V+C TC S F+ F +LSLPL S L+
Sbjct: 923 VALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPLASTSKCTLQ 965
Score = 70.5 bits (171), Expect = 1e-11
Identities = 32/86 (37%), Positives = 50/86 (58%)
Query: 1026 AQAEPINLDSCLRAFTSEEELGESEMYYCSKCKTHCLATKKLDLWRLPPFLIIHLKRFQF 1085
A L CLR F+ EE+L ++ +YCS C+ + KK+++W+LPP L++HLKRF +
Sbjct: 957 ASTSKCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSY 1016
Query: 1086 VNDQWIKSQKIVRFLRESFDPSAFLV 1111
K Q V F E+ D S +++
Sbjct: 1017 DGRWKQKLQTSVDFPLENLDLSQYVI 1042
Score = 53.1 bits (126), Expect = 2e-06
Identities = 23/60 (38%), Positives = 35/60 (58%), Gaps = 1/60 (1%)
Query: 1312 YNLYAISCHSGILSGGHYITYAKN-PNCKWYCYNDSSCEELHPDEIDTDSAYILFYEQQG 1370
YNL+++S H G L GGHY Y KN +W+ ++D ++ + + +AYILFY G
Sbjct: 1051 YNLFSVSNHYGGLDGGHYTAYCKNAARQRWFKFDDHEVSDISVSSVKSSAAYILFYTSLG 1110
>gi|188528692 ubiquitin specific peptidase 2 isoform a [Homo
sapiens]
Length = 605
Score = 152 bits (385), Expect = 2e-36
Identities = 82/204 (40%), Positives = 118/204 (57%), Gaps = 7/204 (3%)
Query: 521 DRQKVPTEKGATGLSNLGNTCFMNSSIQCVSNTQPLTQYFISGRHLYELNRTNPIGMKGH 580
D + +G GL NLGNTCFMNS +QC+SNT+ L Y + ++ +L+ G H
Sbjct: 256 DGMNSKSAQGLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLHH----GSNAH 311
Query: 581 MAKC--YGDLVQELWSGTQKSV-APLKLRRTIAKYAPKFDGFQQQDSQELLAFLLDGLHE 637
A + L+Q +W+ + V +P + + I +YAP+F G+ QQD+QE L FLLDGLH
Sbjct: 312 TALVEEFAKLIQTIWTSSPNDVVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDGLHN 371
Query: 638 DLNRVHEKPYVELKDSDGRPDWEVAAEAWDNHLRRNRSIIVDLFHGQLRSQVKCKTCGHI 697
++NRV +P ++ D PD E + W +L R S I DLF GQL+S + C CG+
Sbjct: 372 EVNRVTLRPKSNPENLDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGYC 431
Query: 698 SVRFDPFNFLSLPLPMDSYMDLEI 721
S FDPF LSLP+ Y ++ +
Sbjct: 432 STVFDPFWDLSLPIAKRGYPEVTL 455
Score = 64.7 bits (156), Expect = 6e-10
Identities = 27/58 (46%), Positives = 38/58 (65%), Gaps = 1/58 (1%)
Query: 1311 IYNLYAISCHSGILSGGHYITYAKNPNC-KWYCYNDSSCEELHPDEIDTDSAYILFYE 1367
+YNLYA+S HSG GGHY Y ++P +W+ +NDSS + ++ T AY+LFYE
Sbjct: 540 VYNLYAVSNHSGTTMGGHYTAYCRSPGTGEWHTFNDSSVTPMSSSQVRTSDAYLLFYE 597
Score = 47.8 bits (112), Expect = 8e-05
Identities = 23/70 (32%), Positives = 37/70 (52%), Gaps = 3/70 (4%)
Query: 1031 INLDSCLRAFTSEEELGESEMYYCSKCKTHCLATKKLDLWRLPPFLIIHLKRFQFVNDQW 1090
+ L C+R FT E+ L E C +C+ KK + R P L++HLKRF ++
Sbjct: 453 VTLMDCMRLFTKEDVLDGDEKPTCCRCRGRKRCIKKFSIQRFPKILVLHLKRF---SESR 509
Query: 1091 IKSQKIVRFL 1100
I++ K+ F+
Sbjct: 510 IRTSKLTTFV 519
>gi|28565285 ubiquitin specific peptidase 2 isoform b [Homo sapiens]
Length = 396
Score = 152 bits (384), Expect = 2e-36
Identities = 81/196 (41%), Positives = 116/196 (59%), Gaps = 7/196 (3%)
Query: 529 KGATGLSNLGNTCFMNSSIQCVSNTQPLTQYFISGRHLYELNRTNPIGMKGHMAKC--YG 586
+G GL NLGNTCFMNS +QC+SNT+ L Y + ++ +L+ G H A +
Sbjct: 55 QGLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLHH----GSNAHTALVEEFA 110
Query: 587 DLVQELWSGTQKSV-APLKLRRTIAKYAPKFDGFQQQDSQELLAFLLDGLHEDLNRVHEK 645
L+Q +W+ + V +P + + I +YAP+F G+ QQD+QE L FLLDGLH ++NRV +
Sbjct: 111 KLIQTIWTSSPNDVVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDGLHNEVNRVTLR 170
Query: 646 PYVELKDSDGRPDWEVAAEAWDNHLRRNRSIIVDLFHGQLRSQVKCKTCGHISVRFDPFN 705
P ++ D PD E + W +L R S I DLF GQL+S + C CG+ S FDPF
Sbjct: 171 PKSNPENLDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGYCSTVFDPFW 230
Query: 706 FLSLPLPMDSYMDLEI 721
LSLP+ Y ++ +
Sbjct: 231 DLSLPIAKRGYPEVTL 246
Score = 64.7 bits (156), Expect = 6e-10
Identities = 27/58 (46%), Positives = 38/58 (65%), Gaps = 1/58 (1%)
Query: 1311 IYNLYAISCHSGILSGGHYITYAKNPNC-KWYCYNDSSCEELHPDEIDTDSAYILFYE 1367
+YNLYA+S HSG GGHY Y ++P +W+ +NDSS + ++ T AY+LFYE
Sbjct: 331 VYNLYAVSNHSGTTMGGHYTAYCRSPGTGEWHTFNDSSVTPMSSSQVRTSDAYLLFYE 388
Score = 47.8 bits (112), Expect = 8e-05
Identities = 23/70 (32%), Positives = 37/70 (52%), Gaps = 3/70 (4%)
Query: 1031 INLDSCLRAFTSEEELGESEMYYCSKCKTHCLATKKLDLWRLPPFLIIHLKRFQFVNDQW 1090
+ L C+R FT E+ L E C +C+ KK + R P L++HLKRF ++
Sbjct: 244 VTLMDCMRLFTKEDVLDGDEKPTCCRCRGRKRCIKKFSIQRFPKILVLHLKRF---SESR 300
Query: 1091 IKSQKIVRFL 1100
I++ K+ F+
Sbjct: 301 IRTSKLTTFV 310
>gi|239751314 PREDICTED: hypothetical protein XP_002347802 [Homo
sapiens]
Length = 179
Score = 149 bits (375), Expect = 2e-35
Identities = 77/130 (59%), Positives = 87/130 (66%), Gaps = 10/130 (7%)
Query: 357 PPPAKREQGSLAPRPVPASR-GGKTLCKGYRQAPPGPPAQFQRPICSASPPWASRFSTPC 415
P AK +QGS APRP AS G KTLCKG RQAPPGP A FQ+ I SASPPW TPC
Sbjct: 46 PEEAKPKQGSSAPRPELASPCGRKTLCKGSRQAPPGPQAHFQQCIWSASPPWVPLPFTPC 105
Query: 416 PGGAVREDTYPVG-TQGVPSLALAQGGPQGSWRFLEWKSMPRLPTDLDIGGPWFPHYDFE 474
P VG +QGVP LA AQGGP+ SWR+L+W S+P+LP D D+ PWFPHYDFE
Sbjct: 106 P--------VLVGLSQGVPRLAPAQGGPRVSWRYLQWNSLPQLPMDSDVVSPWFPHYDFE 157
Query: 475 WSCWVRAISQ 484
CW R S+
Sbjct: 158 QGCWARVPSK 167
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.419
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 61,511,046
Number of Sequences: 37866
Number of extensions: 3260729
Number of successful extensions: 13616
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 179
Number of HSP's successfully gapped in prelim test: 195
Number of HSP's that attempted gapping in prelim test: 12086
Number of HSP's gapped (non-prelim): 1367
length of query: 1406
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1291
effective length of database: 13,892,928
effective search space: 17935770048
effective search space used: 17935770048
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.