Guide to the Human Genome
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Name: CYLD Sequence: fasta or formatted (953aa) NCBI GI: 109637776
Description:

ubiquitin carboxyl-terminal hydrolase CYLD isoform 2

Referenced in:

Dynein and Dynactin
NF-kappaB Pathway
Ubiquitin and Related Protein Modifications

Other entries for this name:
alt mRNA [953aa] ubiquitin carboxyl-terminal hydrolase CYLD isoform 2
alt prot [956aa] ubiquitin carboxyl-terminal hydrolase CYLD isoform 1
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             3.9         37           2
 C cysteine            3.3         31           1
 D aspartate           5.5         52           3
 E glutamate           8.0         76           2
 F phenylalanine       4.9         47           2
 G glycine             7.1         68           2
 H histidine           1.7         16           2
 I isoleucine          5.1         49           2
 K lysine              6.6         63           3
 L leucine            10.3         98           3
 M methionine          2.0         19           1
 N asparagine          4.1         39           1
 P proline             6.2         59           3
 Q glutamine           4.3         41           2
 R arginine            4.5         43           2
 S serine              8.0         76           3
 T threonine           4.5         43           2
 V valine              6.2         59           2
 W tryptophan          0.9          9           1
 Y tyrosine            2.9         28           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   ubiquitin carboxyl-terminal hydrolase CYLD isoform ... 
CYLD                  1.000   ubiquitin carboxyl-terminal hydrolase CYLD isoform ...
CYLD                  0.997   ubiquitin carboxyl-terminal hydrolase CYLD isoform 1...
CLIP2                 0.011   CAP-GLY domain containing linker protein 2 isoform ...
CLIP2                 0.011   CAP-GLY domain containing linker protein 2 isoform 2...
CLIP3                 0.009   CAP-GLY domain containing linker protein 3 
LOC100134138          0.008   PREDICTED: similar to mucin, partial 
LOC100133408          0.008   PREDICTED: similar to mucin 
DCTN1                 0.008   dynactin 1 isoform 3 
DCTN1                 0.008   dynactin 1 isoform 1 
LOC100287144          0.007   PREDICTED: hypothetical protein XP_002342471 
CLIP1                 0.007   restin isoform b 
CLIP1                 0.007   restin isoform a 
CEP350                0.006   centrosome-associated protein 350 
SASH1                 0.006   SAM and SH3 domain containing 1 
SETBP1                0.006   SET binding protein 1 isoform a 
TBCB                  0.006   cytoskeleton associated protein 1 
MLL2                  0.005   myeloid/lymphoid or mixed-lineage leukemia 2 
MUC16                 0.004   mucin 16 
SRRM2                 0.004   splicing coactivator subunit SRm300 
WNK1                  0.004   WNK lysine deficient protein kinase 1 
USP17L8               0.004   PREDICTED: Inactive ubiquitin carboxyl-terminal hyd...
ABI2                  0.004   abl interactor 2 
MUC12                 0.004   PREDICTED: mucin 12 
MUC3A                 0.004   PREDICTED: mucin 3A, intestinal 
MUC12                 0.004   PREDICTED: mucin 12, cell surface associated 
RBM9                  0.004   RNA binding motif protein 9 isoform 5 
DUB3                  0.004   deubiquitinating enzyme 3 
KDM5C                 0.004   jumonji, AT rich interactive domain 1C isoform 2 [H...
KDM5C                 0.004   jumonji, AT rich interactive domain 1C isoform 1 [H...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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