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Search of human proteins with 109633019
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|109633019 Wolf-Hirschhorn syndrome candidate 1 protein
isoform 1 [Homo sapiens]
(1365 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|19913358 Wolf-Hirschhorn syndrome candidate 1 protein isoform... 2848 0.0
gi|19913350 Wolf-Hirschhorn syndrome candidate 1 protein isoform... 2848 0.0
gi|19913348 Wolf-Hirschhorn syndrome candidate 1 protein isoform... 2848 0.0
gi|109633019 Wolf-Hirschhorn syndrome candidate 1 protein isofor... 2848 0.0
gi|6594683 Wolf-Hirschhorn syndrome candidate 1 protein isoform ... 1243 0.0
gi|19913356 Wolf-Hirschhorn syndrome candidate 1 protein isoform... 1243 0.0
gi|13699811 WHSC1L1 protein isoform long [Homo sapiens] 1177 0.0
gi|27477095 nuclear receptor binding SET domain protein 1 isofor... 1051 0.0
gi|19923586 nuclear receptor binding SET domain protein 1 isofor... 1051 0.0
gi|197313748 SET domain containing 2 [Homo sapiens] 203 1e-51
gi|13699813 WHSC1L1 protein isoform short [Homo sapiens] 202 2e-51
gi|110349788 absent, small, or homeotic 1-like [Homo sapiens] 185 3e-46
gi|13375930 suppressor of variegation 3-9 homolog 2 [Homo sapiens] 101 6e-21
gi|19923202 enhancer of zeste homolog 1 [Homo sapiens] 97 1e-19
gi|23510384 enhancer of zeste 2 isoform b [Homo sapiens] 95 5e-19
gi|21361095 enhancer of zeste 2 isoform a [Homo sapiens] 95 5e-19
gi|210032580 SET domain containing 1B [Homo sapiens] 91 8e-18
gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [... 89 3e-17
gi|4507321 suppressor of variegation 3-9 homolog 1 [Homo sapiens] 89 4e-17
gi|194306650 SET domain and mariner transposase fusion [Homo sap... 83 2e-15
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 83 2e-15
gi|55741677 SET domain containing 1A [Homo sapiens] 82 3e-15
gi|156142199 euchromatic histone-lysine N-methyltransferase 2 is... 79 2e-14
gi|156142197 euchromatic histone-lysine N-methyltransferase 2 is... 79 2e-14
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 79 3e-14
gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo s... 79 4e-14
gi|224465233 euchromatic histone-lysine N-methyltransferase 1 is... 78 5e-14
gi|4504191 mutS homolog 6 [Homo sapiens] 72 4e-12
gi|94721344 zinc finger, CW type with PWWP domain 1 [Homo sapiens] 65 3e-10
gi|24308089 chromodomain helicase DNA binding protein 5 [Homo sa... 62 3e-09
>gi|19913358 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
[Homo sapiens]
Length = 1365
Score = 2848 bits (7383), Expect = 0.0
Identities = 1365/1365 (100%), Positives = 1365/1365 (100%)
Query: 1 MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG 60
MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG
Sbjct: 1 MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG 60
Query: 61 VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG 120
VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG
Sbjct: 61 VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG 120
Query: 121 SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE 180
SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE
Sbjct: 121 SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE 180
Query: 181 QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV 240
QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV
Sbjct: 181 QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV 240
Query: 241 SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ 300
SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ
Sbjct: 241 SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ 300
Query: 301 APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA 360
APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA
Sbjct: 301 APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA 360
Query: 361 KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK 420
KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK
Sbjct: 361 KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK 420
Query: 421 STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG 480
STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG
Sbjct: 421 STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG 480
Query: 481 EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE 540
EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE
Sbjct: 481 EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE 540
Query: 541 AEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR 600
AEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR
Sbjct: 541 AEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR 600
Query: 601 NRASTAASSALGFSKSSSPSASLTENEVSDSPGDEPSESPYESADETQTEVSVSSKKSER 660
NRASTAASSALGFSKSSSPSASLTENEVSDSPGDEPSESPYESADETQTEVSVSSKKSER
Sbjct: 601 NRASTAASSALGFSKSSSPSASLTENEVSDSPGDEPSESPYESADETQTEVSVSSKKSER 660
Query: 661 GVTAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSCFVC 720
GVTAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSCFVC
Sbjct: 661 GVTAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSCFVC 720
Query: 721 KESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKG 780
KESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKG
Sbjct: 721 KESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKG 780
Query: 781 KMMRCVRCPVAYHSGDACLAAGCSVIASNSIICTAHFTARKGKRHHAHVNVSWCFVCSKG 840
KMMRCVRCPVAYHSGDACLAAGCSVIASNSIICTAHFTARKGKRHHAHVNVSWCFVCSKG
Sbjct: 781 KMMRCVRCPVAYHSGDACLAAGCSVIASNSIICTAHFTARKGKRHHAHVNVSWCFVCSKG 840
Query: 841 GSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEVCH 900
GSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEVCH
Sbjct: 841 GSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEVCH 900
Query: 901 PKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKN 960
PKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKN
Sbjct: 901 PKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKN 960
Query: 961 ALQEAEARFREIKLQREARETQESERKPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKP 1020
ALQEAEARFREIKLQREARETQESERKPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKP
Sbjct: 961 ALQEAEARFREIKLQREARETQESERKPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKP 1020
Query: 1021 TDENPCGFDSECLNRMLMFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTDGKGWGLVAK 1080
TDENPCGFDSECLNRMLMFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTDGKGWGLVAK
Sbjct: 1021 TDENPCGFDSECLNRMLMFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTDGKGWGLVAK 1080
Query: 1081 RDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRIIDAGPKGNYSRFM 1140
RDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRIIDAGPKGNYSRFM
Sbjct: 1081 RDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRIIDAGPKGNYSRFM 1140
Query: 1141 NHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCGASNCSG 1200
NHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCGASNCSG
Sbjct: 1141 NHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCGASNCSG 1200
Query: 1201 FLGDRPKTSTTLSSEEKGKKTKKKTRRRRAKGEGKRQSEDECFRCGDGGQLVLCDRKFCT 1260
FLGDRPKTSTTLSSEEKGKKTKKKTRRRRAKGEGKRQSEDECFRCGDGGQLVLCDRKFCT
Sbjct: 1201 FLGDRPKTSTTLSSEEKGKKTKKKTRRRRAKGEGKRQSEDECFRCGDGGQLVLCDRKFCT 1260
Query: 1261 KAYHLSCLGLGKRPFGKWECPWHHCDVCGKPSTSFCHLCPNSFCKEHQDGTAFSCTPDGR 1320
KAYHLSCLGLGKRPFGKWECPWHHCDVCGKPSTSFCHLCPNSFCKEHQDGTAFSCTPDGR
Sbjct: 1261 KAYHLSCLGLGKRPFGKWECPWHHCDVCGKPSTSFCHLCPNSFCKEHQDGTAFSCTPDGR 1320
Query: 1321 SYCCEHDLGAASVRSTKTEKPPPEPGKPKGKRRRRRGWRRVTEGK 1365
SYCCEHDLGAASVRSTKTEKPPPEPGKPKGKRRRRRGWRRVTEGK
Sbjct: 1321 SYCCEHDLGAASVRSTKTEKPPPEPGKPKGKRRRRRGWRRVTEGK 1365
>gi|19913350 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
[Homo sapiens]
Length = 1365
Score = 2848 bits (7383), Expect = 0.0
Identities = 1365/1365 (100%), Positives = 1365/1365 (100%)
Query: 1 MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG 60
MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG
Sbjct: 1 MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG 60
Query: 61 VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG 120
VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG
Sbjct: 61 VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG 120
Query: 121 SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE 180
SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE
Sbjct: 121 SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE 180
Query: 181 QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV 240
QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV
Sbjct: 181 QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV 240
Query: 241 SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ 300
SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ
Sbjct: 241 SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ 300
Query: 301 APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA 360
APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA
Sbjct: 301 APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA 360
Query: 361 KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK 420
KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK
Sbjct: 361 KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK 420
Query: 421 STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG 480
STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG
Sbjct: 421 STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG 480
Query: 481 EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE 540
EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE
Sbjct: 481 EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE 540
Query: 541 AEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR 600
AEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR
Sbjct: 541 AEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR 600
Query: 601 NRASTAASSALGFSKSSSPSASLTENEVSDSPGDEPSESPYESADETQTEVSVSSKKSER 660
NRASTAASSALGFSKSSSPSASLTENEVSDSPGDEPSESPYESADETQTEVSVSSKKSER
Sbjct: 601 NRASTAASSALGFSKSSSPSASLTENEVSDSPGDEPSESPYESADETQTEVSVSSKKSER 660
Query: 661 GVTAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSCFVC 720
GVTAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSCFVC
Sbjct: 661 GVTAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSCFVC 720
Query: 721 KESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKG 780
KESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKG
Sbjct: 721 KESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKG 780
Query: 781 KMMRCVRCPVAYHSGDACLAAGCSVIASNSIICTAHFTARKGKRHHAHVNVSWCFVCSKG 840
KMMRCVRCPVAYHSGDACLAAGCSVIASNSIICTAHFTARKGKRHHAHVNVSWCFVCSKG
Sbjct: 781 KMMRCVRCPVAYHSGDACLAAGCSVIASNSIICTAHFTARKGKRHHAHVNVSWCFVCSKG 840
Query: 841 GSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEVCH 900
GSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEVCH
Sbjct: 841 GSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEVCH 900
Query: 901 PKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKN 960
PKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKN
Sbjct: 901 PKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKN 960
Query: 961 ALQEAEARFREIKLQREARETQESERKPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKP 1020
ALQEAEARFREIKLQREARETQESERKPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKP
Sbjct: 961 ALQEAEARFREIKLQREARETQESERKPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKP 1020
Query: 1021 TDENPCGFDSECLNRMLMFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTDGKGWGLVAK 1080
TDENPCGFDSECLNRMLMFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTDGKGWGLVAK
Sbjct: 1021 TDENPCGFDSECLNRMLMFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTDGKGWGLVAK 1080
Query: 1081 RDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRIIDAGPKGNYSRFM 1140
RDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRIIDAGPKGNYSRFM
Sbjct: 1081 RDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRIIDAGPKGNYSRFM 1140
Query: 1141 NHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCGASNCSG 1200
NHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCGASNCSG
Sbjct: 1141 NHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCGASNCSG 1200
Query: 1201 FLGDRPKTSTTLSSEEKGKKTKKKTRRRRAKGEGKRQSEDECFRCGDGGQLVLCDRKFCT 1260
FLGDRPKTSTTLSSEEKGKKTKKKTRRRRAKGEGKRQSEDECFRCGDGGQLVLCDRKFCT
Sbjct: 1201 FLGDRPKTSTTLSSEEKGKKTKKKTRRRRAKGEGKRQSEDECFRCGDGGQLVLCDRKFCT 1260
Query: 1261 KAYHLSCLGLGKRPFGKWECPWHHCDVCGKPSTSFCHLCPNSFCKEHQDGTAFSCTPDGR 1320
KAYHLSCLGLGKRPFGKWECPWHHCDVCGKPSTSFCHLCPNSFCKEHQDGTAFSCTPDGR
Sbjct: 1261 KAYHLSCLGLGKRPFGKWECPWHHCDVCGKPSTSFCHLCPNSFCKEHQDGTAFSCTPDGR 1320
Query: 1321 SYCCEHDLGAASVRSTKTEKPPPEPGKPKGKRRRRRGWRRVTEGK 1365
SYCCEHDLGAASVRSTKTEKPPPEPGKPKGKRRRRRGWRRVTEGK
Sbjct: 1321 SYCCEHDLGAASVRSTKTEKPPPEPGKPKGKRRRRRGWRRVTEGK 1365
>gi|19913348 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
[Homo sapiens]
Length = 1365
Score = 2848 bits (7383), Expect = 0.0
Identities = 1365/1365 (100%), Positives = 1365/1365 (100%)
Query: 1 MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG 60
MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG
Sbjct: 1 MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG 60
Query: 61 VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG 120
VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG
Sbjct: 61 VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG 120
Query: 121 SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE 180
SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE
Sbjct: 121 SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE 180
Query: 181 QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV 240
QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV
Sbjct: 181 QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV 240
Query: 241 SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ 300
SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ
Sbjct: 241 SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ 300
Query: 301 APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA 360
APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA
Sbjct: 301 APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA 360
Query: 361 KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK 420
KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK
Sbjct: 361 KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK 420
Query: 421 STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG 480
STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG
Sbjct: 421 STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG 480
Query: 481 EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE 540
EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE
Sbjct: 481 EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE 540
Query: 541 AEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR 600
AEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR
Sbjct: 541 AEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR 600
Query: 601 NRASTAASSALGFSKSSSPSASLTENEVSDSPGDEPSESPYESADETQTEVSVSSKKSER 660
NRASTAASSALGFSKSSSPSASLTENEVSDSPGDEPSESPYESADETQTEVSVSSKKSER
Sbjct: 601 NRASTAASSALGFSKSSSPSASLTENEVSDSPGDEPSESPYESADETQTEVSVSSKKSER 660
Query: 661 GVTAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSCFVC 720
GVTAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSCFVC
Sbjct: 661 GVTAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSCFVC 720
Query: 721 KESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKG 780
KESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKG
Sbjct: 721 KESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKG 780
Query: 781 KMMRCVRCPVAYHSGDACLAAGCSVIASNSIICTAHFTARKGKRHHAHVNVSWCFVCSKG 840
KMMRCVRCPVAYHSGDACLAAGCSVIASNSIICTAHFTARKGKRHHAHVNVSWCFVCSKG
Sbjct: 781 KMMRCVRCPVAYHSGDACLAAGCSVIASNSIICTAHFTARKGKRHHAHVNVSWCFVCSKG 840
Query: 841 GSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEVCH 900
GSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEVCH
Sbjct: 841 GSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEVCH 900
Query: 901 PKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKN 960
PKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKN
Sbjct: 901 PKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKN 960
Query: 961 ALQEAEARFREIKLQREARETQESERKPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKP 1020
ALQEAEARFREIKLQREARETQESERKPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKP
Sbjct: 961 ALQEAEARFREIKLQREARETQESERKPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKP 1020
Query: 1021 TDENPCGFDSECLNRMLMFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTDGKGWGLVAK 1080
TDENPCGFDSECLNRMLMFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTDGKGWGLVAK
Sbjct: 1021 TDENPCGFDSECLNRMLMFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTDGKGWGLVAK 1080
Query: 1081 RDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRIIDAGPKGNYSRFM 1140
RDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRIIDAGPKGNYSRFM
Sbjct: 1081 RDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRIIDAGPKGNYSRFM 1140
Query: 1141 NHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCGASNCSG 1200
NHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCGASNCSG
Sbjct: 1141 NHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCGASNCSG 1200
Query: 1201 FLGDRPKTSTTLSSEEKGKKTKKKTRRRRAKGEGKRQSEDECFRCGDGGQLVLCDRKFCT 1260
FLGDRPKTSTTLSSEEKGKKTKKKTRRRRAKGEGKRQSEDECFRCGDGGQLVLCDRKFCT
Sbjct: 1201 FLGDRPKTSTTLSSEEKGKKTKKKTRRRRAKGEGKRQSEDECFRCGDGGQLVLCDRKFCT 1260
Query: 1261 KAYHLSCLGLGKRPFGKWECPWHHCDVCGKPSTSFCHLCPNSFCKEHQDGTAFSCTPDGR 1320
KAYHLSCLGLGKRPFGKWECPWHHCDVCGKPSTSFCHLCPNSFCKEHQDGTAFSCTPDGR
Sbjct: 1261 KAYHLSCLGLGKRPFGKWECPWHHCDVCGKPSTSFCHLCPNSFCKEHQDGTAFSCTPDGR 1320
Query: 1321 SYCCEHDLGAASVRSTKTEKPPPEPGKPKGKRRRRRGWRRVTEGK 1365
SYCCEHDLGAASVRSTKTEKPPPEPGKPKGKRRRRRGWRRVTEGK
Sbjct: 1321 SYCCEHDLGAASVRSTKTEKPPPEPGKPKGKRRRRRGWRRVTEGK 1365
>gi|109633019 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
[Homo sapiens]
Length = 1365
Score = 2848 bits (7383), Expect = 0.0
Identities = 1365/1365 (100%), Positives = 1365/1365 (100%)
Query: 1 MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG 60
MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG
Sbjct: 1 MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG 60
Query: 61 VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG 120
VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG
Sbjct: 61 VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG 120
Query: 121 SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE 180
SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE
Sbjct: 121 SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE 180
Query: 181 QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV 240
QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV
Sbjct: 181 QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV 240
Query: 241 SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ 300
SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ
Sbjct: 241 SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ 300
Query: 301 APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA 360
APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA
Sbjct: 301 APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA 360
Query: 361 KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK 420
KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK
Sbjct: 361 KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK 420
Query: 421 STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG 480
STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG
Sbjct: 421 STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG 480
Query: 481 EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE 540
EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE
Sbjct: 481 EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE 540
Query: 541 AEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR 600
AEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR
Sbjct: 541 AEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR 600
Query: 601 NRASTAASSALGFSKSSSPSASLTENEVSDSPGDEPSESPYESADETQTEVSVSSKKSER 660
NRASTAASSALGFSKSSSPSASLTENEVSDSPGDEPSESPYESADETQTEVSVSSKKSER
Sbjct: 601 NRASTAASSALGFSKSSSPSASLTENEVSDSPGDEPSESPYESADETQTEVSVSSKKSER 660
Query: 661 GVTAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSCFVC 720
GVTAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSCFVC
Sbjct: 661 GVTAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSCFVC 720
Query: 721 KESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKG 780
KESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKG
Sbjct: 721 KESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKG 780
Query: 781 KMMRCVRCPVAYHSGDACLAAGCSVIASNSIICTAHFTARKGKRHHAHVNVSWCFVCSKG 840
KMMRCVRCPVAYHSGDACLAAGCSVIASNSIICTAHFTARKGKRHHAHVNVSWCFVCSKG
Sbjct: 781 KMMRCVRCPVAYHSGDACLAAGCSVIASNSIICTAHFTARKGKRHHAHVNVSWCFVCSKG 840
Query: 841 GSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEVCH 900
GSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEVCH
Sbjct: 841 GSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEVCH 900
Query: 901 PKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKN 960
PKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKN
Sbjct: 901 PKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKN 960
Query: 961 ALQEAEARFREIKLQREARETQESERKPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKP 1020
ALQEAEARFREIKLQREARETQESERKPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKP
Sbjct: 961 ALQEAEARFREIKLQREARETQESERKPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKP 1020
Query: 1021 TDENPCGFDSECLNRMLMFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTDGKGWGLVAK 1080
TDENPCGFDSECLNRMLMFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTDGKGWGLVAK
Sbjct: 1021 TDENPCGFDSECLNRMLMFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTDGKGWGLVAK 1080
Query: 1081 RDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRIIDAGPKGNYSRFM 1140
RDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRIIDAGPKGNYSRFM
Sbjct: 1081 RDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRIIDAGPKGNYSRFM 1140
Query: 1141 NHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCGASNCSG 1200
NHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCGASNCSG
Sbjct: 1141 NHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCGASNCSG 1200
Query: 1201 FLGDRPKTSTTLSSEEKGKKTKKKTRRRRAKGEGKRQSEDECFRCGDGGQLVLCDRKFCT 1260
FLGDRPKTSTTLSSEEKGKKTKKKTRRRRAKGEGKRQSEDECFRCGDGGQLVLCDRKFCT
Sbjct: 1201 FLGDRPKTSTTLSSEEKGKKTKKKTRRRRAKGEGKRQSEDECFRCGDGGQLVLCDRKFCT 1260
Query: 1261 KAYHLSCLGLGKRPFGKWECPWHHCDVCGKPSTSFCHLCPNSFCKEHQDGTAFSCTPDGR 1320
KAYHLSCLGLGKRPFGKWECPWHHCDVCGKPSTSFCHLCPNSFCKEHQDGTAFSCTPDGR
Sbjct: 1261 KAYHLSCLGLGKRPFGKWECPWHHCDVCGKPSTSFCHLCPNSFCKEHQDGTAFSCTPDGR 1320
Query: 1321 SYCCEHDLGAASVRSTKTEKPPPEPGKPKGKRRRRRGWRRVTEGK 1365
SYCCEHDLGAASVRSTKTEKPPPEPGKPKGKRRRRRGWRRVTEGK
Sbjct: 1321 SYCCEHDLGAASVRSTKTEKPPPEPGKPKGKRRRRRGWRRVTEGK 1365
>gi|6594683 Wolf-Hirschhorn syndrome candidate 1 protein isoform 4
[Homo sapiens]
Length = 629
Score = 1243 bits (3217), Expect = 0.0
Identities = 628/628 (100%), Positives = 628/628 (100%)
Query: 1 MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG 60
MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG
Sbjct: 1 MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG 60
Query: 61 VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG 120
VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG
Sbjct: 61 VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG 120
Query: 121 SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE 180
SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE
Sbjct: 121 SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE 180
Query: 181 QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV 240
QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV
Sbjct: 181 QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV 240
Query: 241 SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ 300
SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ
Sbjct: 241 SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ 300
Query: 301 APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA 360
APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA
Sbjct: 301 APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA 360
Query: 361 KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK 420
KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK
Sbjct: 361 KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK 420
Query: 421 STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG 480
STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG
Sbjct: 421 STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG 480
Query: 481 EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE 540
EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE
Sbjct: 481 EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE 540
Query: 541 AEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR 600
AEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR
Sbjct: 541 AEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR 600
Query: 601 NRASTAASSALGFSKSSSPSASLTENEV 628
NRASTAASSALGFSKSSSPSASLTENEV
Sbjct: 601 NRASTAASSALGFSKSSSPSASLTENEV 628
>gi|19913356 Wolf-Hirschhorn syndrome candidate 1 protein isoform 3
[Homo sapiens]
Length = 647
Score = 1243 bits (3215), Expect = 0.0
Identities = 628/632 (99%), Positives = 629/632 (99%)
Query: 1 MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG 60
MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG
Sbjct: 1 MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG 60
Query: 61 VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG 120
VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG
Sbjct: 61 VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG 120
Query: 121 SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE 180
SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE
Sbjct: 121 SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE 180
Query: 181 QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV 240
QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV
Sbjct: 181 QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV 240
Query: 241 SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ 300
SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ
Sbjct: 241 SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ 300
Query: 301 APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA 360
APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA
Sbjct: 301 APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA 360
Query: 361 KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK 420
KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK
Sbjct: 361 KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK 420
Query: 421 STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG 480
STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG
Sbjct: 421 STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG 480
Query: 481 EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE 540
EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE
Sbjct: 481 EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE 540
Query: 541 AEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR 600
AEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR
Sbjct: 541 AEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR 600
Query: 601 NRASTAASSALGFSKSSSPSASLTENEVSDSP 632
NRASTAASSALGFSKSSSPSASLTENE+ P
Sbjct: 601 NRASTAASSALGFSKSSSPSASLTENELLWEP 632
>gi|13699811 WHSC1L1 protein isoform long [Homo sapiens]
Length = 1437
Score = 1177 bits (3046), Expect = 0.0
Identities = 617/1308 (47%), Positives = 800/1308 (61%), Gaps = 129/1308 (9%)
Query: 111 PPNTTPIKNGSPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRK 170
P P K GSPEIKLKITKT NG+ LFESS+CGD +V SE K E++ + RK
Sbjct: 140 PQTVIPKKTGSPEIKLKITKTIQNGRELFESSLCGDLLNEVQASEHTKSKHESR-KEKRK 198
Query: 171 RSIKYDSLLEQGLVEAALVS-----------KISSPSDK--KIPAKKESCP--------- 208
+S K+DS + + ++ + S+K + P KE P
Sbjct: 199 KSNKHDSSRSEERKSHKIPKLEPEEQNRPNERVDTVSEKPREEPVLKEEAPVQPILSSVP 258
Query: 209 ----NTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHV 264
+TG +K+ VGDLVWSKV YPWWPCMVS+DP L +TK+ + AR+YHV
Sbjct: 259 TTEVSTG------VKFQVGDLVWSKVGTYPWWPCMVSSDPQLEVHTKIN--TRGAREYHV 310
Query: 265 QFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQAPTKAEKIKLLKPISGKLRAQWEM 324
QFF + PERAW+ EK + ++G Q+E+L E+ KQA +EK K+ KP + RAQW++
Sbjct: 311 QFFSNQPERAWVHEKRVREYKGHKQYEELLAEATKQASNHSEKQKIRKPRPQRERAQWDI 370
Query: 325 GIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVAKEAGIAAESLGEMAESSGVSEEAA 384
GI AE+A M+ EER ++TF+Y+ Q AK++ + + + V
Sbjct: 371 GIAHAEKALKMTREERIEQYTFIYIDKQPEEALSQAKKSVASKTEVKKTRRPRSVLNTQP 430
Query: 385 E--NPKSVREECIPMKRRRRAKLCSSAETLESHPDIGKSTPQKTAEADPRRGVGSPPGRK 442
E N V + RR ++ ++ E P + KTA A R+ + +
Sbjct: 431 EQTNAGEVASSLSSTEIRRHSQRRHTSAEEEEPPPV--KIAWKTAAA--RKSLPASITMH 486
Query: 443 KTTVSMPRSRKGDAASQFLVFCQKHR-------DEVVAEHPDASGEEIEELLRSQWSLLS 495
K ++ + + VF ++ D+ V G + E +R Q L+
Sbjct: 487 KGSLDLQKCNMSPVVKIEQVFALQNATGDGKFIDQFVYS-TKGIGNKTEISVRGQDRLII 545
Query: 496 EKQRARYNTKFALVAPVQAEEDS-GNVNGKKRNHTKRIQDPTEDAEAEDTPRKRLRTDKH 554
R V+ +A S G+V K++ + R + +E + E P+K+++ ++
Sbjct: 546 STPNQRNEKPTQSVSSPEATSGSTGSVEKKQQRRSIRTRSESEKS-TEVVPKKKIKKEQV 604
Query: 555 SLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKRNRASTAASSALGFS 614
+T+ T +T K +SD+CKPLKKR+RAST
Sbjct: 605 -----ETVPQATVKTGLQKG------------ASEISDSCKPLKKRSRASTDVEMTSSAY 647
Query: 615 KSSSPSASLTENEVSDSPGDEPSESPYESADETQTEV-SVSSKKSERGV-TAKKEYVCQL 672
+ +S S S +++ G + +SP +AD ++V S+ S S RG +KK+ VCQ+
Sbjct: 648 RDTSDSDSRGLSDLQVGFGKQV-DSPSATADADVSDVQSMDSSLSRRGTGMSKKDTVCQI 706
Query: 673 CEKPG-SLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSCFVCKESKTDVKRCV 731
CE G SL+ CEG CC FHL CLGL+ P+ +F C EC +G H CF CK S DVKRC
Sbjct: 707 CESSGDSLIPCEGECCKHFHLECLGLASLPDSKFICMECKTGQHPCFSCKVSGKDVKRCS 766
Query: 732 VTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKGKMMRCVRCPVA 791
V CGKFYHEACV+K+P +FES+GFRCP H C +C + + SKG+MMRC+RCPVA
Sbjct: 767 VGACGKFYHEACVRKFPTAIFESKGFRCPQHCCSACSMEKDIH-KASKGRMMRCLRCPVA 825
Query: 792 YHSGDACLAAGCSVIASNSIICTAHFTARKGKRHHAHVNVSWCFVCS------------- 838
YHSGDAC+AAG +++S +IC+ H K + + VNV +CFVC+
Sbjct: 826 YHSGDACIAAGSMLVSSYILICSNH---SKRSSNSSAVNVGFCFVCARGLIVQDHSDPMF 882
Query: 839 ------------------------------------KGGSLLCCESCPAAFHPDCLNIEM 862
KGG LLCCESCPA+FHP+CL+IEM
Sbjct: 883 SSYAYKSHYLLNESNRAELMKLPMIPSSSASKKKCEKGGRLLCCESCPASFHPECLSIEM 942
Query: 863 PDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEVCHPKNVPPNIQKMKHEIGEFPVFF 922
P+G W CNDC+AGKKLH++ I+WVKLGNYRWWPAE+C+P++VP NIQ +KH++G+FPVFF
Sbjct: 943 PEGCWNCNDCKAGKKLHYKQIVWVKLGNYRWWPAEICNPRSVPLNIQGLKHDLGDFPVFF 1002
Query: 923 FGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKNALQEAEARFREIKLQREARETQ 982
FGS DYYW HQ RVFPY+EGD+ S +G I + FK AL+EA RF+E+K QRE++E
Sbjct: 1003 FGSHDYYWVHQGRVFPYVEGDK-SFAEGQTSINKTFKKALEEAAKRFQELKAQRESKEAL 1061
Query: 983 ESE---RKPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKPTDENPCGFDSECLNRMLMF 1039
E E RKPPPYKHIK NK GKVQI AD+SEIP+CNCKP DENPCG +SECLNRML +
Sbjct: 1062 EIEKNSRKPPPYKHIKANKVIGKVQIQVADLSEIPRCNCKPADENPCGLESECLNRMLQY 1121
Query: 1040 ECHPQVCPAGEFCQNQCFTKRQYPETKIIKTDGKGWGLVAKRDIRKGEFVNEYVGELIDE 1099
ECHPQVCPAG+ CQNQCFTKR YP+ +IIKT+ +GWGL KR I+KGEFVNEYVGELIDE
Sbjct: 1122 ECHPQVCPAGDRCQNQCFTKRLYPDAEIIKTERRGWGLRTKRSIKKGEFVNEYVGELIDE 1181
Query: 1100 EECMARIKHAHENDITHFYMLTIDKDRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDT 1159
EEC RIK AHEN +T+FYMLT+ KDRIIDAGPKGNYSRFMNHSC PNCET KWTVNGD
Sbjct: 1182 EECRLRIKRAHENSVTNFYMLTVTKDRIIDAGPKGNYSRFMNHSCNPNCETQKWTVNGDV 1241
Query: 1160 RVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCGASNCSGFLGDRPKTSTTLSSEEKGK 1219
RVGLFA+CDIPAG ELTFNYNLDCLGN +T C CGA NCSGFLG RPK++ ++EEK K
Sbjct: 1242 RVGLFALCDIPAGMELTFNYNLDCLGNGRTECHCGADNCSGFLGVRPKSACASTNEEKAK 1301
Query: 1220 KTKKKTRRRRAKGEGKRQSEDECFRCGDGGQLVLCDRKFCTKAYHLSCLGLGKRPFGKWE 1279
K K +RR+ K E K+ ED CF+CGDGG+LV+CD+K C KAYHL CL L + P+GKWE
Sbjct: 1302 NAKLKQKRRKIKTEPKQMHEDYCFQCGDGGELVMCDKKDCPKAYHLLCLNLTQPPYGKWE 1361
Query: 1280 CPWHHCDVCGKPSTSFCHLCPNSFCKEHQDGTAFSCTPDGRSYCCEHD 1327
CPWH CD C + SFC CP+SFCK+H+ G +GR C EHD
Sbjct: 1362 CPWHQCDECSSAAVSFCEFCPHSFCKDHEKGALVPSALEGRLCCSEHD 1409
Score = 38.5 bits (88), Expect = 0.044
Identities = 35/121 (28%), Positives = 45/121 (37%), Gaps = 20/121 (16%)
Query: 1231 KGEGKRQSEDECFRC-GDGGQLVLCDRKFCTKAYHLSCLGLGKRPFGKWEC--------P 1281
+G G + + C C G L+ C+ + C K +HL CLGL P K+ C P
Sbjct: 693 RGTGMSKKDTVCQICESSGDSLIPCEGE-CCKHFHLECLGLASLPDSKFICMECKTGQHP 751
Query: 1282 WHHCDVCGKP----STSFC-----HLCPNSFCKEHQDGTAFSCTPDGRSYC-CEHDLGAA 1331
C V GK S C C F + F C S C E D+ A
Sbjct: 752 CFSCKVSGKDVKRCSVGACGKFYHEACVRKFPTAIFESKGFRCPQHCCSACSMEKDIHKA 811
Query: 1332 S 1332
S
Sbjct: 812 S 812
>gi|27477095 nuclear receptor binding SET domain protein 1 isoform a
[Homo sapiens]
Length = 2427
Score = 1051 bits (2719), Expect = 0.0
Identities = 477/765 (62%), Positives = 582/765 (76%), Gaps = 12/765 (1%)
Query: 595 KPLKKRNRASTAASSALGFSKSSSPSASLTENEVSDSP---GDEPSESPYESADETQTEV 651
KP K++ + AA K+ S + +E P P E+ E +
Sbjct: 1198 KPRKRKRQRHAAAKMQCKKVKNDDSSKEIPGSEGELMPHRTATSPKETVEEGVEHDPGMP 1257
Query: 652 SVSSKKSERGV-TAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSEC 710
+ + ERG A KE VCQ CEK G LLLCE CCGAFHL CLGL+ P G+F C+EC
Sbjct: 1258 ASKKMQGERGGGAALKENVCQNCEKLGELLLCEAQCCGAFHLECLGLTEMPRGKFICNEC 1317
Query: 711 ASGIHSCFVCKESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHAS 770
+GIH+CFVCK+S DVKRC++ CGKFYHE CV+KYP TV +++GFRC LH C++CHA+
Sbjct: 1318 RTGIHTCFVCKQSGEDVKRCLLPLCGKFYHEECVQKYPPTVMQNKGFRCSLHICITCHAA 1377
Query: 771 NPSNPRPSKGKMMRCVRCPVAYHSGDACLAAGCSVIASNSIICTAHFTARKGKRHHAHVN 830
NP+N SKG++MRCVRCPVAYH+ D CLAAG ++ASNSIIC HFT R+G R+H HVN
Sbjct: 1378 NPANVSASKGRLMRCVRCPVAYHANDFCLAAGSKILASNSIICPNHFTPRRGCRNHEHVN 1437
Query: 831 VSWCFVCSKGGSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGN 890
VSWCFVCS+GGSLLCC+SCPAAFH +CLNI++P+G+W+CNDC+AGKK H+++I+WVK+G
Sbjct: 1438 VSWCFVCSEGGSLLCCDSCPAAFHRECLNIDIPEGNWYCNDCKAGKKPHYREIVWVKVGR 1497
Query: 891 YRWWPAEVCHPKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQG 950
YRWWPAE+CHP+ VP NI KM+H++GEFPV FFGS DY WTHQARVFPYMEGD S+ +
Sbjct: 1498 YRWWPAEICHPRAVPSNIDKMRHDVGEFPVLFFGSNDYLWTHQARVFPYMEGDVSSKDKM 1557
Query: 951 VRGIGRVFKNALQEAEARFREIKLQREARETQE---SERKPPPYKHIKVNKPYGKVQIYT 1007
+G+ +K ALQEA ARF E+K Q+E R+ QE +++KPPPYKHIKVN+P G+VQI+T
Sbjct: 1558 GKGVDGTYKKALQEAAARFEELKAQKELRQLQEDRKNDKKPPPYKHIKVNRPIGRVQIFT 1617
Query: 1008 ADISEIPKCNCKPTDENPCGFDSECLNRMLMFECHPQVCPAGEFCQNQCFTKRQYPETKI 1067
AD+SEIP+CNCK TDENPCG DSEC+NRML++ECHP VCPAG CQNQCF+KRQYPE +I
Sbjct: 1618 ADLSEIPRCNCKATDENPCGIDSECINRMLLYECHPTVCPAGGRCQNQCFSKRQYPEVEI 1677
Query: 1068 IKTDGKGWGLVAKRDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRI 1127
+T +GWGL K DI+KGEFVNEYVGELIDEEEC ARI++A E+DIT+FYMLT+DKDRI
Sbjct: 1678 FRTLQRGWGLRTKTDIKKGEFVNEYVGELIDEEECRARIRYAQEHDITNFYMLTLDKDRI 1737
Query: 1128 IDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNE 1187
IDAGPKGNY+RFMNH CQPNCET KW+VNGDTRVGLFA+ DI AGTELTFNYNL+CLGN
Sbjct: 1738 IDAGPKGNYARFMNHCCQPNCETQKWSVNGDTRVGLFALSDIKAGTELTFNYNLECLGNG 1797
Query: 1188 KTVCRCGASNCSGFLGDRPKTSTTLSSEEKGKKTKKKTR-RRRAKGEGKRQSEDECFRCG 1246
KTVC+CGA NCSGFLG RPK +++EEK KK KKK + +RR +GE ++ EDECF CG
Sbjct: 1798 KTVCKCGAPNCSGFLGVRPKNQP-IATEEKSKKFKKKQQGKRRTQGEITKEREDECFSCG 1856
Query: 1247 DGGQLVLCDRKFCTKAYHLSCLGLGKRPFGKWECPWHHCDVCGKPSTSFCHLCPNSFCKE 1306
D GQLV C + C K YH CL L KRP GKWECPWH CD+CGK + SFC +CP+SFCK+
Sbjct: 1857 DAGQLVSCKKPGCPKVYHADCLNLTKRPAGKWECPWHQCDICGKEAASFCEMCPSSFCKQ 1916
Query: 1307 HQDGTAFSCTPDGRSYCCEHD-LGAASVRSTKTEK--PPPEPGKP 1348
H++G F DGR C EHD G + + + PPP P P
Sbjct: 1917 HREGMLFISKLDGRLSCTEHDPCGPNPLEPGEIREYVPPPVPLPP 1961
Score = 98.6 bits (244), Expect = 4e-20
Identities = 52/143 (36%), Positives = 84/143 (58%), Gaps = 16/143 (11%)
Query: 193 SSPSDKKIP---AKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMVSADPLLHSY 249
SS + +++P KK+S P LKY VGDL+W+K PWWPC + +DPL++++
Sbjct: 31 SSSTSQELPFCQPKKKSTP---------LKYEVGDLIWAKFKRRPWWPCRICSDPLINTH 81
Query: 250 TKLK-GQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQAPTKAEKI 308
+K+K ++ RQY+V+ FGD ERAW+ K++V FEG QFE+L + K ++
Sbjct: 82 SKMKVSNRRPYRQYYVEAFGDPSERAWVAGKAIVMFEGRHQFEEL---PVLRRRGKQKEK 138
Query: 309 KLLKPISGKLRAQWEMGIVQAEE 331
+ K+ ++WE + AE+
Sbjct: 139 GYRHKVPQKILSKWEASVGLAEQ 161
Score = 30.8 bits (68), Expect = 9.3
Identities = 11/34 (32%), Positives = 16/34 (47%), Gaps = 2/34 (5%)
Query: 868 FCNDCRAGKKLHFQ--DIIWVKLGNYRWWPAEVC 899
FC + L ++ D+IW K WWP +C
Sbjct: 40 FCQPKKKSTPLKYEVGDLIWAKFKRRPWWPCRIC 73
>gi|19923586 nuclear receptor binding SET domain protein 1 isoform b
[Homo sapiens]
Length = 2696
Score = 1051 bits (2719), Expect = 0.0
Identities = 477/765 (62%), Positives = 582/765 (76%), Gaps = 12/765 (1%)
Query: 595 KPLKKRNRASTAASSALGFSKSSSPSASLTENEVSDSP---GDEPSESPYESADETQTEV 651
KP K++ + AA K+ S + +E P P E+ E +
Sbjct: 1467 KPRKRKRQRHAAAKMQCKKVKNDDSSKEIPGSEGELMPHRTATSPKETVEEGVEHDPGMP 1526
Query: 652 SVSSKKSERGV-TAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSEC 710
+ + ERG A KE VCQ CEK G LLLCE CCGAFHL CLGL+ P G+F C+EC
Sbjct: 1527 ASKKMQGERGGGAALKENVCQNCEKLGELLLCEAQCCGAFHLECLGLTEMPRGKFICNEC 1586
Query: 711 ASGIHSCFVCKESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHAS 770
+GIH+CFVCK+S DVKRC++ CGKFYHE CV+KYP TV +++GFRC LH C++CHA+
Sbjct: 1587 RTGIHTCFVCKQSGEDVKRCLLPLCGKFYHEECVQKYPPTVMQNKGFRCSLHICITCHAA 1646
Query: 771 NPSNPRPSKGKMMRCVRCPVAYHSGDACLAAGCSVIASNSIICTAHFTARKGKRHHAHVN 830
NP+N SKG++MRCVRCPVAYH+ D CLAAG ++ASNSIIC HFT R+G R+H HVN
Sbjct: 1647 NPANVSASKGRLMRCVRCPVAYHANDFCLAAGSKILASNSIICPNHFTPRRGCRNHEHVN 1706
Query: 831 VSWCFVCSKGGSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGN 890
VSWCFVCS+GGSLLCC+SCPAAFH +CLNI++P+G+W+CNDC+AGKK H+++I+WVK+G
Sbjct: 1707 VSWCFVCSEGGSLLCCDSCPAAFHRECLNIDIPEGNWYCNDCKAGKKPHYREIVWVKVGR 1766
Query: 891 YRWWPAEVCHPKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQG 950
YRWWPAE+CHP+ VP NI KM+H++GEFPV FFGS DY WTHQARVFPYMEGD S+ +
Sbjct: 1767 YRWWPAEICHPRAVPSNIDKMRHDVGEFPVLFFGSNDYLWTHQARVFPYMEGDVSSKDKM 1826
Query: 951 VRGIGRVFKNALQEAEARFREIKLQREARETQE---SERKPPPYKHIKVNKPYGKVQIYT 1007
+G+ +K ALQEA ARF E+K Q+E R+ QE +++KPPPYKHIKVN+P G+VQI+T
Sbjct: 1827 GKGVDGTYKKALQEAAARFEELKAQKELRQLQEDRKNDKKPPPYKHIKVNRPIGRVQIFT 1886
Query: 1008 ADISEIPKCNCKPTDENPCGFDSECLNRMLMFECHPQVCPAGEFCQNQCFTKRQYPETKI 1067
AD+SEIP+CNCK TDENPCG DSEC+NRML++ECHP VCPAG CQNQCF+KRQYPE +I
Sbjct: 1887 ADLSEIPRCNCKATDENPCGIDSECINRMLLYECHPTVCPAGGRCQNQCFSKRQYPEVEI 1946
Query: 1068 IKTDGKGWGLVAKRDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRI 1127
+T +GWGL K DI+KGEFVNEYVGELIDEEEC ARI++A E+DIT+FYMLT+DKDRI
Sbjct: 1947 FRTLQRGWGLRTKTDIKKGEFVNEYVGELIDEEECRARIRYAQEHDITNFYMLTLDKDRI 2006
Query: 1128 IDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNE 1187
IDAGPKGNY+RFMNH CQPNCET KW+VNGDTRVGLFA+ DI AGTELTFNYNL+CLGN
Sbjct: 2007 IDAGPKGNYARFMNHCCQPNCETQKWSVNGDTRVGLFALSDIKAGTELTFNYNLECLGNG 2066
Query: 1188 KTVCRCGASNCSGFLGDRPKTSTTLSSEEKGKKTKKKTR-RRRAKGEGKRQSEDECFRCG 1246
KTVC+CGA NCSGFLG RPK +++EEK KK KKK + +RR +GE ++ EDECF CG
Sbjct: 2067 KTVCKCGAPNCSGFLGVRPKNQP-IATEEKSKKFKKKQQGKRRTQGEITKEREDECFSCG 2125
Query: 1247 DGGQLVLCDRKFCTKAYHLSCLGLGKRPFGKWECPWHHCDVCGKPSTSFCHLCPNSFCKE 1306
D GQLV C + C K YH CL L KRP GKWECPWH CD+CGK + SFC +CP+SFCK+
Sbjct: 2126 DAGQLVSCKKPGCPKVYHADCLNLTKRPAGKWECPWHQCDICGKEAASFCEMCPSSFCKQ 2185
Query: 1307 HQDGTAFSCTPDGRSYCCEHD-LGAASVRSTKTEK--PPPEPGKP 1348
H++G F DGR C EHD G + + + PPP P P
Sbjct: 2186 HREGMLFISKLDGRLSCTEHDPCGPNPLEPGEIREYVPPPVPLPP 2230
Score = 98.6 bits (244), Expect = 4e-20
Identities = 52/143 (36%), Positives = 84/143 (58%), Gaps = 16/143 (11%)
Query: 193 SSPSDKKIP---AKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMVSADPLLHSY 249
SS + +++P KK+S P LKY VGDL+W+K PWWPC + +DPL++++
Sbjct: 300 SSSTSQELPFCQPKKKSTP---------LKYEVGDLIWAKFKRRPWWPCRICSDPLINTH 350
Query: 250 TKLK-GQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQAPTKAEKI 308
+K+K ++ RQY+V+ FGD ERAW+ K++V FEG QFE+L + K ++
Sbjct: 351 SKMKVSNRRPYRQYYVEAFGDPSERAWVAGKAIVMFEGRHQFEEL---PVLRRRGKQKEK 407
Query: 309 KLLKPISGKLRAQWEMGIVQAEE 331
+ K+ ++WE + AE+
Sbjct: 408 GYRHKVPQKILSKWEASVGLAEQ 430
Score = 39.3 bits (90), Expect = 0.026
Identities = 55/213 (25%), Positives = 83/213 (38%), Gaps = 36/213 (16%)
Query: 24 APEILGS--ANGKTPSCEVNRECSVFLSKAQLSSSLQEGVMQKFNGHDALP-FIPADKLK 80
APE S NG++ E C++ LS G Q G D+ +IP +L+
Sbjct: 24 APEDKDSPFGNGQSNFSEPLNGCTMQLSTVS-------GTSQNAYGQDSPSCYIPLRRLQ 76
Query: 81 DLTSRVFNGE--PGAHDAKLRFESQEMKG--IGTPPNTT---------------PIKNGS 121
DL S + N E G+ D F+ E TP T P N S
Sbjct: 77 DLASMI-NVEYLNGSADGSESFQDPEKSDSRAQTPIVCTSLSPGGPTALAMKQEPSCNNS 135
Query: 122 PEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKA------RRNRKRSIKY 175
PE+++K+TKT NG FE+ C D A S+ + E+++ + Y
Sbjct: 136 PELQVKVTKTIKNGFLHFENFTCVDDADVDSEMDPEQPVTEDESIEEIFEETQTNATCNY 195
Query: 176 DSLLEQGLVEAALVSKISSPSDKKIPAKKESCP 208
++ E G+ A + S+P + K P
Sbjct: 196 ETKSENGVKVAMGSEQDSTPESRHGAVKSPFLP 228
Score = 30.8 bits (68), Expect = 9.3
Identities = 11/34 (32%), Positives = 16/34 (47%), Gaps = 2/34 (5%)
Query: 868 FCNDCRAGKKLHFQ--DIIWVKLGNYRWWPAEVC 899
FC + L ++ D+IW K WWP +C
Sbjct: 309 FCQPKKKSTPLKYEVGDLIWAKFKRRPWWPCRIC 342
>gi|197313748 SET domain containing 2 [Homo sapiens]
Length = 2564
Score = 203 bits (516), Expect = 1e-51
Identities = 99/231 (42%), Positives = 140/231 (60%), Gaps = 14/231 (6%)
Query: 1015 KCNCKPTDENP-------CGFDSECLNRMLMFECHPQVCPAGEFCQNQCFTKRQYPETKI 1067
+C C P ++ CG D CLNR+LM EC + CP G++C N+ F ++Q+ + ++
Sbjct: 1498 QCECTPLSKDERAQGEIACGED--CLNRLLMIECSSR-CPNGDYCSNRRFQRKQHADVEV 1554
Query: 1068 IKTDGKGWGLVAKRDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRI 1127
I T+ KGWGL A +D+ FV EY GE++D +E AR+K N H+Y + + D I
Sbjct: 1555 ILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHKEFKARVKEYARNKNIHYYFMALKNDEI 1614
Query: 1128 IDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNE 1187
IDA KGN SRFMNHSC+PNCET KWTVNG RVG F +P+G+ELTF+Y G E
Sbjct: 1615 IDATQKGNCSRFMNHSCEPNCETQKWTVNGQLRVGFFTTKLVPSGSELTFDYQFQRYGKE 1674
Query: 1188 KTVCRCGASNCSGFLGDRPKTSTTLSSEEKGKKTKKKTRRRRAKGEGKRQS 1238
C CG++NC G+LG + S + G K KK+ R++ +G+ ++
Sbjct: 1675 AQKCFCGSANCRGYLGGENRVSIRAA----GGKMKKERSRKKDSVDGELEA 1721
>gi|13699813 WHSC1L1 protein isoform short [Homo sapiens]
Length = 645
Score = 202 bits (514), Expect = 2e-51
Identities = 155/500 (31%), Positives = 241/500 (48%), Gaps = 58/500 (11%)
Query: 111 PPNTTPIKNGSPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRK 170
P P K GSPEIKLKITKT NG+ LFESS+CGD +V SE K E++ + RK
Sbjct: 140 PQTVIPKKTGSPEIKLKITKTIQNGRELFESSLCGDLLNEVQASEHTKSKHESR-KEKRK 198
Query: 171 RSIKYDSLLEQGLVEAALVS-----------KISSPSDK--KIPAKKESCP--------- 208
+S K+DS + + ++ + S+K + P KE P
Sbjct: 199 KSNKHDSSRSEERKSHKIPKLEPEEQNRPNERVDTVSEKPREEPVLKEEAPVQPILSSVP 258
Query: 209 ----NTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHV 264
+TG +K+ VGDLVWSKV YPWWPCMVS+DP L +TK+ + AR+YHV
Sbjct: 259 TTEVSTG------VKFQVGDLVWSKVGTYPWWPCMVSSDPQLEVHTKIN--TRGAREYHV 310
Query: 265 QFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQAPTKAEKIKLLKPISGKLRAQWEM 324
QFF + PERAW+ EK + ++G Q+E+L E+ KQA +EK K+ KP + RAQW++
Sbjct: 311 QFFSNQPERAWVHEKRVREYKGHKQYEELLAEATKQASNHSEKQKIRKPRPQRERAQWDI 370
Query: 325 GIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVAKEAGIAAESLGEMAESSGVSEEAA 384
GI AE+A M+ EER ++TF+Y+ Q AK++ + + + V
Sbjct: 371 GIAHAEKALKMTREERIEQYTFIYIDKQPEEALSQAKKSVASKTEVKKTRRPRSVLNTQP 430
Query: 385 E--NPKSVREECIPMKRRRRAKLCSSAETLESHPDIGKSTPQKTAEADPRRGVGSPPGRK 442
E N V + RR ++ ++ E P + KTA A R+ + +
Sbjct: 431 EQTNAGEVASSLSSTEIRRHSQRRHTSAEEEEPPPV--KIAWKTAAA--RKSLPASITMH 486
Query: 443 KTTVSMPRSRKGDAASQFLVFC-------QKHRDEVVAEHPDASGEEIEELLRSQWSLL- 494
K ++ + + VF K D+ V G + E +R Q L+
Sbjct: 487 KGSLDLQKCNMSPVVKIEQVFALQNATGDGKFIDQFVYS-TKGIGNKTEISVRGQDRLII 545
Query: 495 -SEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAEAEDTPRKRLRTDK 553
+ QR T+ ++ +P +G+V K++ + R + +E + E P+K+++ +
Sbjct: 546 STPNQRNEKPTQ-SVSSPEATSGSTGSVEKKQQRRSIRTRSESEKS-TEVVPKKKIKKE- 602
Query: 554 HSLRKRDTITDKTARTSSYK 573
+ +T+ T +T K
Sbjct: 603 ----QVETVPQATVKTGLQK 618
Score = 42.0 bits (97), Expect = 0.004
Identities = 20/66 (30%), Positives = 31/66 (46%), Gaps = 1/66 (1%)
Query: 875 GKKLHFQDIIWVKLGNYRWWPAEVCHPKNVPPNIQKMKHEIGEFPVFFFGSK-DYYWTHQ 933
G K D++W K+G Y WWP V + + + E+ V FF ++ + W H+
Sbjct: 265 GVKFQVGDLVWSKVGTYPWWPCMVSSDPQLEVHTKINTRGAREYHVQFFSNQPERAWVHE 324
Query: 934 ARVFPY 939
RV Y
Sbjct: 325 KRVREY 330
>gi|110349788 absent, small, or homeotic 1-like [Homo sapiens]
Length = 2964
Score = 185 bits (469), Expect = 3e-46
Identities = 99/259 (38%), Positives = 147/259 (56%), Gaps = 11/259 (4%)
Query: 986 RKP--PPYKHIKVNKPYGKVQIYTADISEIPKCNCK-PTDENPCGFDSECLNRMLMFECH 1042
+KP P YK I+ N V + E CNCK P D+ G +CLNRM+ EC
Sbjct: 2062 KKPDVPLYKKIRSNV---YVDVKPLSGYEATTCNCKKPDDDTRKGCVDDCLNRMIFAECS 2118
Query: 1043 PQVCPAGEFCQNQCFTKRQYPET-KIIKTDGKGWGLVAKRDIRKGEFVNEYVGELIDEEE 1101
P CP GE C NQ + ++ + + + + KGWG+ K ++ G+F+ EY+GE++ E+E
Sbjct: 2119 PNTCPCGEQCCNQRIQRHEWVQCLERFRAEEKGWGIRTKEPLKAGQFIIEYLGEVVSEQE 2178
Query: 1102 CMARIKHAHENDITHFYMLTIDKDRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTRV 1161
R+ + N H Y L +D +ID+ GN +RF+NHSC PNCE KW+VNG R+
Sbjct: 2179 FRNRMIEQYHNHSDH-YCLNLDSGMVIDSYRMGNEARFINHSCDPNCEMQKWSVNGVYRI 2237
Query: 1162 GLFAVCDIPAGTELTFNYNLDCLGNEK-TVCRCGASNCSGFLGDRPKTSTTLSSEEKGK- 1219
GL+A+ D+PAGTELT++YN EK +C+CG C G +G + + L+S + +
Sbjct: 2238 GLYALKDMPAGTELTYDYNFHSFNVEKQQLCKCGFEKCRGIIGGKSQRVNGLTSSKNSQP 2297
Query: 1220 -KTKKKTRRRRAKGEGKRQ 1237
T KK+ R + K + K +
Sbjct: 2298 MATHKKSGRSKEKRKSKHK 2316
>gi|13375930 suppressor of variegation 3-9 homolog 2 [Homo sapiens]
Length = 350
Score = 101 bits (251), Expect = 6e-21
Identities = 65/185 (35%), Positives = 93/185 (50%), Gaps = 21/185 (11%)
Query: 1038 MFECHPQVCPAGEFCQNQCFTKRQYPETKIIKT-DGKGWGLVAKRDIRKGEFVNEYVGEL 1096
++EC+ + C G C N+ K I +T +G+GWG+ I++ FV EYVGE+
Sbjct: 166 IYECNSR-CQCGPDCPNRIVQKGTQYSLCIFRTSNGRGWGVKTLVKIKRMSFVMEYVGEV 224
Query: 1097 IDEEECMARIKHAHENDITHFYMLTIDKDRI-IDAGPKGNYSRFMNHSCQPNCETLKWTV 1155
I EE R + IT+ + L + D +DA GN S F+NHSC PN + +
Sbjct: 225 ITSEEAERRGQFYDNKGITYLFDLDYESDEFTVDAARYGNVSHFVNHSCDPNLQVFNVFI 284
Query: 1156 -NGDT---RVGLFAVCDIPAGTELTFNYNLDCLGN--------------EKTVCRCGASN 1197
N DT R+ LF+ I AG ELTF+Y + G+ +TVC+CGA
Sbjct: 285 DNLDTRLPRIALFSTRTINAGEELTFDYQMKGSGDISSDSIDHSPAKKRVRTVCKCGAVT 344
Query: 1198 CSGFL 1202
C G+L
Sbjct: 345 CRGYL 349
>gi|19923202 enhancer of zeste homolog 1 [Homo sapiens]
Length = 747
Score = 96.7 bits (239), Expect = 1e-19
Identities = 61/182 (33%), Positives = 90/182 (49%), Gaps = 20/182 (10%)
Query: 1016 CNCKPTDENP---CGFDSECLNR-----MLMFECHPQVC---PAGEF-------CQNQCF 1057
C C P +N C ++C + + + EC P +C A E C+N
Sbjct: 548 CQCNPDCQNRFPGCRCKTQCNTKQCPCYLAVRECDPDLCLTCGASEHWDCKVVSCKNCSI 607
Query: 1058 TKRQYPETKIIKTDGKGWGLVAKRDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHF 1117
+ + +D GWG K ++K EF++EY GELI ++E R K ++ ++ F
Sbjct: 608 QRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADRRGK-VYDKYMSSF 666
Query: 1118 YMLTIDKDRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTF 1177
+ ++ D ++DA KGN RF NHS PNC VNGD R+G+FA I AG EL F
Sbjct: 667 -LFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIFAKRAIQAGEELFF 725
Query: 1178 NY 1179
+Y
Sbjct: 726 DY 727
>gi|23510384 enhancer of zeste 2 isoform b [Homo sapiens]
Length = 707
Score = 94.7 bits (234), Expect = 5e-19
Identities = 58/182 (31%), Positives = 86/182 (47%), Gaps = 23/182 (12%)
Query: 1011 SEIPKCNCKP---TDENPCGFDSECLNRMLMFECHPQVC----------PAGEFCQNQCF 1057
+ P C CK T + PC + + EC P +C C+N
Sbjct: 516 NRFPGCRCKAQCNTKQCPC--------YLAVRECDPDLCLTCGAADHWDSKNVSCKNCSI 567
Query: 1058 TKRQYPETKIIKTDGKGWGLVAKRDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHF 1117
+ + +D GWG+ K ++K EF++EY GE+I ++E R K ++ + F
Sbjct: 568 QRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGK-VYDKYMCSF 626
Query: 1118 YMLTIDKDRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTF 1177
+ ++ D ++DA KGN RF NHS PNC VNGD R+G+FA I G EL F
Sbjct: 627 -LFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFF 685
Query: 1178 NY 1179
+Y
Sbjct: 686 DY 687
>gi|21361095 enhancer of zeste 2 isoform a [Homo sapiens]
Length = 751
Score = 94.7 bits (234), Expect = 5e-19
Identities = 58/182 (31%), Positives = 86/182 (47%), Gaps = 23/182 (12%)
Query: 1011 SEIPKCNCKP---TDENPCGFDSECLNRMLMFECHPQVC----------PAGEFCQNQCF 1057
+ P C CK T + PC + + EC P +C C+N
Sbjct: 560 NRFPGCRCKAQCNTKQCPC--------YLAVRECDPDLCLTCGAADHWDSKNVSCKNCSI 611
Query: 1058 TKRQYPETKIIKTDGKGWGLVAKRDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHF 1117
+ + +D GWG+ K ++K EF++EY GE+I ++E R K ++ + F
Sbjct: 612 QRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGK-VYDKYMCSF 670
Query: 1118 YMLTIDKDRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTF 1177
+ ++ D ++DA KGN RF NHS PNC VNGD R+G+FA I G EL F
Sbjct: 671 -LFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFF 729
Query: 1178 NY 1179
+Y
Sbjct: 730 DY 731
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 90.9 bits (224), Expect = 8e-18
Identities = 50/137 (36%), Positives = 69/137 (50%), Gaps = 1/137 (0%)
Query: 1066 KIIKTDGKGWGLVAKRDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKD 1125
K K+ WGL A I E V EYVG+ I + R K + I YM +D D
Sbjct: 1787 KFCKSHIHDWGLFAMEPIAADEMVIEYVGQNIRQVIADMREKRYEDEGIGSSYMFRVDHD 1846
Query: 1126 RIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLG 1185
IIDA GN++RF+NHSC PNC TV ++ +++ I E+T++Y +
Sbjct: 1847 TIIDATKCGNFARFINHSCNPNCYAKVITVESQKKIVIYSKQHINVNEEITYDYKFP-IE 1905
Query: 1186 NEKTVCRCGASNCSGFL 1202
+ K C CG+ NC G L
Sbjct: 1906 DVKIPCLCGSENCRGTL 1922
Score = 32.7 bits (73), Expect = 2.4
Identities = 33/133 (24%), Positives = 55/133 (41%), Gaps = 3/133 (2%)
Query: 515 EEDSGNVNGKKRNHTKRIQDPTEDAEAEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKA 574
E DSG +K + ++ + E+ EAE+ + D S RD + T+ +A
Sbjct: 1028 ELDSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDS-DDRDESENDDEDTALSEA 1086
Query: 575 MEAASSLKSQAATKNLSDACKPLKKRNRASTAASSALGFSKSSSPSASLTENEVSDSPGD 634
E + T +S + + + ++ SS S SSPS+S E EV +
Sbjct: 1087 SEKDEGDSDEEET--VSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEE 1144
Query: 635 EPSESPYESADET 647
E E A+E+
Sbjct: 1145 EEEEEEEMVAEES 1157
>gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [Homo
sapiens]
Length = 3969
Score = 89.0 bits (219), Expect = 3e-17
Identities = 50/130 (38%), Positives = 68/130 (52%), Gaps = 2/130 (1%)
Query: 1074 GWGLVAKRDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRIIDAGPK 1133
G GL KR+I GE V EY G +I + R K+ I YM ID ++DA
Sbjct: 3840 GRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSKGIG-CYMFRIDDSEVVDATMH 3898
Query: 1134 GNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCL-GNEKTVCR 1192
GN +RF+NHSC+PNC + ++G + +FA+ I G ELT++Y + K C
Sbjct: 3899 GNAARFINHSCEPNCYSRVINIDGQKHIVIFAMRKIYRGEELTYDYKFPIEDASNKLPCN 3958
Query: 1193 CGASNCSGFL 1202
CGA C FL
Sbjct: 3959 CGAKKCRKFL 3968
Score = 36.6 bits (83), Expect = 0.17
Identities = 30/112 (26%), Positives = 44/112 (39%), Gaps = 8/112 (7%)
Query: 669 VCQLCEKPGSL--LLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSCFVCKESKTD 726
VC LC G + + C+ CC FH CL + RP + C C VC
Sbjct: 1433 VCFLCASSGHVEFVYCQ-VCCEPFHKFCLEENERPLEDQLENWCCRRCKFCHVCGRQHQA 1491
Query: 727 VKRCV-VTQCGKFYHEACV-KKYPL-TVFESRGFRCPLHSCVSCHASNPSNP 775
K+ + +C YH C+ YP + + + C CV C + + P
Sbjct: 1492 TKQLLECNKCRNSYHPECLGPNYPTKPTKKKKVWICT--KCVRCKSCGSTTP 1541
Score = 33.5 bits (75), Expect = 1.4
Identities = 21/75 (28%), Positives = 30/75 (40%), Gaps = 10/75 (13%)
Query: 1242 CFRCGDGGQLVLCDRKFCTKAYHLSCLGLGKRP----FGKWEC-PWHHCDVCGKPSTSF- 1295
CF C G + + C + +H CL +RP W C C VCG+ +
Sbjct: 1434 CFLCASSGHVEFVYCQVCCEPFHKFCLEENERPLEDQLENWCCRRCKFCHVCGRQHQATK 1493
Query: 1296 ----CHLCPNSFCKE 1306
C+ C NS+ E
Sbjct: 1494 QLLECNKCRNSYHPE 1508
>gi|4507321 suppressor of variegation 3-9 homolog 1 [Homo sapiens]
Length = 412
Score = 88.6 bits (218), Expect = 4e-17
Identities = 63/194 (32%), Positives = 89/194 (45%), Gaps = 30/194 (15%)
Query: 1038 MFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTD-GKGWGLVAKRDIRKGEFVNEYVGEL 1096
++EC+ + C G C N+ K + I +TD G+GWG+ IRK FV EYVGE+
Sbjct: 219 IYECNSR-CRCGYDCPNRVVQKGIRYDLCIFRTDDGRGWGVRTLEKIRKNSFVMEYVGEI 277
Query: 1097 IDEEECMARIKHAHENDITHFYMLTIDKD-RIIDAGPKGNYSRFMNHSCQPNCETLKWTV 1155
I EE R + T+ + L +D +DA GN S F+NHSC PN + +
Sbjct: 278 ITSEEAERRGQIYDRQGATYLFDLDYVEDVYTVDAAYYGNISHFVNHSCDPNLQVYNVFI 337
Query: 1156 NG----DTRVGLFAVCDIPAGTELTFNYNL--DCLGNEKT-------------------- 1189
+ R+ FA I AG ELTF+YN+ D + E T
Sbjct: 338 DNLDERLPRIAFFATRTIRAGEELTFDYNMQVDPVDMESTRMDSNFGLAGLPGSPKKRVR 397
Query: 1190 -VCRCGASNCSGFL 1202
C+CG +C +L
Sbjct: 398 IECKCGTESCRKYL 411
>gi|194306650 SET domain and mariner transposase fusion [Homo sapiens]
Length = 684
Score = 83.2 bits (204), Expect = 2e-15
Identities = 64/217 (29%), Positives = 98/217 (45%), Gaps = 35/217 (16%)
Query: 1016 CNCKPTDENPCGFDSECLNRM--------LMFECHPQVCPAGEFCQNQCFTKRQYPETKI 1067
C+C EN D+ CL + +FEC+ +C + C+N+ K ++
Sbjct: 87 CSCLRHGENYD--DNSCLRDIGSGGKYAEPVFECNV-LCRCSDHCRNRVVQKGLQFHFQV 143
Query: 1068 IKTDGKGWGLVAKRDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDK--- 1124
KT KGWGL I KG FV EY GE++ E RI ++D Y++ I +
Sbjct: 144 FKTHKKGWGLRTLEFIPKGRFVCEYAGEVLGFSEVQRRIHLQTKSDSN--YIIAIREHVY 201
Query: 1125 -----DRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDT-RVGLFAVCDIPAGTELTFN 1178
+ +D GN RF+NHSC+PN + ++ ++ LFA DI EL+++
Sbjct: 202 NGQVMETFVDPTYIGNIGRFLNHSCEPNLLMIPVRIDSMVPKLALFAAKDIVPEEELSYD 261
Query: 1179 YNLDCL-------------GNEKTVCRCGASNCSGFL 1202
Y+ L G + C CGA +C+ FL
Sbjct: 262 YSGRYLNLTVSEDKERLDHGKLRKPCYCGAKSCTAFL 298
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 82.8 bits (203), Expect = 2e-15
Identities = 46/127 (36%), Positives = 68/127 (53%), Gaps = 2/127 (1%)
Query: 1073 KGWGLVAKRDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRIIDAGP 1132
+G GL A +D+ K V EY+G +I E R K +E YM I+ + +IDA
Sbjct: 5407 QGLGLYAAKDLEKHTMVIEYIGTIIRNEVANRREK-IYEEQNRGIYMFRINNEHVIDATL 5465
Query: 1133 KGNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNE-KTVC 1191
G +R++NHSC PNC T + + ++ + + IP G ELT++Y D ++ K C
Sbjct: 5466 TGGPARYINHSCAPNCVAEVVTFDKEDKIIIISSRRIPKGEELTYDYQFDFEDDQHKIPC 5525
Query: 1192 RCGASNC 1198
CGA NC
Sbjct: 5526 HCGAWNC 5532
Score = 48.9 bits (115), Expect = 3e-05
Identities = 35/114 (30%), Positives = 48/114 (42%), Gaps = 13/114 (11%)
Query: 661 GVTAKKEYVCQLCEKPGSL---LLCEGPCCGAFHLACL--GLSRRPEGRFTCSECASGIH 715
G +E C +CE PG L C C +H ACL L+ R + C EC
Sbjct: 220 GAAYLEEARCAVCEGPGELCDLFFCTS-CGHHYHGACLDTALTARKRAGWQCPECKV--- 275
Query: 716 SCFVCKESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHA 769
C C++ D K V C K YH C+K P+ + ++C +C C A
Sbjct: 276 -CQACRKPGNDSKMLVCETCDKGYHTFCLKP-PMEELPAHSWKC--KACRVCRA 325
Score = 48.5 bits (114), Expect = 4e-05
Identities = 54/214 (25%), Positives = 72/214 (33%), Gaps = 28/214 (13%)
Query: 670 CQLCEKPGSLLLCEGPCCGA-FHLACLGLS----RRPEGRFTCSECASGIH-----SCFV 719
C C + G+ + C P C +H C S + C E + G C V
Sbjct: 172 CSHCTRLGASIPCRSPGCPRLYHFPCATASGSFLSMKTLQLLCPEHSEGAAYLEEARCAV 231
Query: 720 CKESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASN-PSNPRPS 778
C+ T CG YH AC+ LT + G++CP C C A P N
Sbjct: 232 CEGPGELCDLFFCTSCGHHYHGACLDT-ALTARKRAGWQCP--ECKVCQACRKPGND--- 285
Query: 779 KGKMMRCVRCPVAYHSGDACLAAGCSVIASNSIICTAHFTARKGKRHHAHV--------N 830
KM+ C C YH+ CL + ++S C A R A + N
Sbjct: 286 -SKMLVCETCDKGYHT--FCLKPPMEELPAHSWKCKACRVCRACGAGSAELNPNSEWFEN 342
Query: 831 VSWCFVCSKGGSLLCCESCPAAFHPDCLNIEMPD 864
S C C K S P C P+
Sbjct: 343 YSLCHRCHKAQGGQTIRSVAEQHTPVCSRFSPPE 376
Score = 48.1 bits (113), Expect = 6e-05
Identities = 61/275 (22%), Positives = 97/275 (35%), Gaps = 27/275 (9%)
Query: 536 TEDAEAEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACK 595
T+ + A D RL TD + D S KA +S A +
Sbjct: 1246 TDVSPARDEGSLRLCTDSLPETDDSLLCDAGTAISGGKAEGEKGRRRSSPARSRIKQGRS 1305
Query: 596 ---PLKKRNRASTAASSALGFSKSSSPSASLTENEVSDSPGDEPSESPYESADETQTEVS 652
P ++R R G ++ S ++S+ V+D PS+ E D+T
Sbjct: 1306 SSFPGRRRPRGGAHGGRGRGRARLKSTASSIETLVVADIDSS-PSKEEEEEDDDTMQNTV 1364
Query: 653 VSSKKSERGVTAKKEYVCQLCEK-----PGSLLLCEGPCCGAFHLACLGLSRRPE---GR 704
V +++ V + +C +C G LL C C +H C+
Sbjct: 1365 VLFSNTDKFVLMQD--MCVVCGSFGRGAEGHLLACS-QCSQCYHPYCVNSKITKVMLLKG 1421
Query: 705 FTCSECASGIHSCFVCKESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCP-LHS 763
+ C EC C VC ++ + + C YH C+ PL G++C S
Sbjct: 1422 WRCVECIV----CEVCGQASDPSRLLLCDDCDISYHTYCLDP-PLLTVPKGGWKCKWCVS 1476
Query: 764 CVSCHASNP------SNPRPSKGKMMRCVRCPVAY 792
C+ C A++P N G V CP+ +
Sbjct: 1477 CMQCGAASPGFHCEWQNSYTHCGPCASLVTCPICH 1511
Score = 40.0 bits (92), Expect = 0.015
Identities = 29/108 (26%), Positives = 37/108 (34%), Gaps = 22/108 (20%)
Query: 788 CPVAYHSGDACLAAGCSVIASNSIICTAHFTARKGKRHH---------AHVNVSW----- 833
CP A C+V +C F G +H A W
Sbjct: 214 CPEHSEGAAYLEEARCAVCEGPGELCDLFFCTSCGHHYHGACLDTALTARKRAGWQCPEC 273
Query: 834 --CFVCSKGGS---LLCCESCPAAFHPDCLN---IEMPDGSWFCNDCR 873
C C K G+ +L CE+C +H CL E+P SW C CR
Sbjct: 274 KVCQACRKPGNDSKMLVCETCDKGYHTFCLKPPMEELPAHSWKCKACR 321
Score = 31.2 bits (69), Expect = 7.1
Identities = 15/48 (31%), Positives = 20/48 (41%), Gaps = 9/48 (18%)
Query: 834 CFVCSK-----GGSLLCCESCPAAFHPDCLNIEMPD----GSWFCNDC 872
C VC G LL C C +HP C+N ++ W C +C
Sbjct: 1380 CVVCGSFGRGAEGHLLACSQCSQCYHPYCVNSKITKVMLLKGWRCVEC 1427
>gi|55741677 SET domain containing 1A [Homo sapiens]
Length = 1707
Score = 82.4 bits (202), Expect = 3e-15
Identities = 45/128 (35%), Positives = 63/128 (49%), Gaps = 1/128 (0%)
Query: 1075 WGLVAKRDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRIIDAGPKG 1134
WGL A I E V EYVG+ I + R K + I Y+ +D D IIDA G
Sbjct: 1580 WGLFAMEPIAADEMVIEYVGQNIRQMVADMREKRYVQEGIGSSYLFRVDHDTIIDATKCG 1639
Query: 1135 NYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCG 1194
N +RF+NH C PNC T+ ++ +++ I E+T++Y L + K C CG
Sbjct: 1640 NLARFINHCCTPNCYAKVITIESQKKIVIYSKQPIGVDEEITYDYKFP-LEDNKIPCLCG 1698
Query: 1195 ASNCSGFL 1202
+C G L
Sbjct: 1699 TESCRGSL 1706
Score = 34.7 bits (78), Expect = 0.64
Identities = 38/150 (25%), Positives = 60/150 (40%), Gaps = 11/150 (7%)
Query: 511 PVQAEEDSGNVNGKKRNHTKRIQDPTEDAEAEDTPRKRLRTDKHSLRKRDT-----ITDK 565
P + +E+ G GK R + + E+A E + K D+ D T K
Sbjct: 941 PPKRDEERGKTQGKHRK-SFALDSEGEEASQESSSEKDEEDDEEDEEDEDREEAVDTTKK 999
Query: 566 TARTSSYKAMEAASSLKSQAATKNLSDACKPLKKRNRASTAASSALGFSKSSSPSASLTE 625
S + E+ SS K + + + +S+++SS+ S SSS S+S +
Sbjct: 1000 ETEVSDGEDEESDSSSKCSLYADSDGENDSTSDSESSSSSSSSSS---SSSSSSSSSSSS 1056
Query: 626 NEVSDSPGDEPSESP--YESADETQTEVSV 653
+ S S +E E P SA EV V
Sbjct: 1057 SSESSSEDEEEEERPAALPSASPPPREVPV 1086
>gi|156142199 euchromatic histone-lysine N-methyltransferase 2 isoform
b [Homo sapiens]
Length = 1176
Score = 79.3 bits (194), Expect = 2e-14
Identities = 72/245 (29%), Positives = 110/245 (44%), Gaps = 40/245 (16%)
Query: 983 ESERKPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKPTDENP----------CGFDSEC 1032
+ E P YK+I N + I +I+ + C C + C +D +
Sbjct: 908 DGEPCPEDYKYISENCETSTMNI-DRNITHLQHCTCVDDCSSSNCLCGQLSIRCWYDKDG 966
Query: 1033 --------LNRMLMFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTDGKGWGLVAKRDIR 1084
+ L+FEC+ Q C C+N+ ++ +T GWG+ A + I
Sbjct: 967 RLLQEFNKIEPPLIFECN-QACSCWRNCKNRVVQSGIKVRLQLYRTAKMGWGVRALQTIP 1025
Query: 1085 KGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTID-KD---RIIDAGPKGNYSRFM 1140
+G F+ EYVGELI + E R E+D Y+ +D KD IDA GN SRF+
Sbjct: 1026 QGTFICEYVGELISDAEADVR-----EDD---SYLFDLDNKDGEVYCIDARYYGNISRFI 1077
Query: 1141 NHSCQPNCETLK-WTVNGD---TRVGLFAVCDIPAGTELTFNYNLDCLGNEKT---VCRC 1193
NH C PN ++ + ++ D R+ F+ DI G EL F+Y D + K+ C+C
Sbjct: 1078 NHLCDPNIIPVRVFMLHQDLRFPRIAFFSSRDIRTGEELGFDYG-DRFWDIKSKYFTCQC 1136
Query: 1194 GASNC 1198
G+ C
Sbjct: 1137 GSEKC 1141
>gi|156142197 euchromatic histone-lysine N-methyltransferase 2 isoform
a [Homo sapiens]
Length = 1210
Score = 79.3 bits (194), Expect = 2e-14
Identities = 72/245 (29%), Positives = 110/245 (44%), Gaps = 40/245 (16%)
Query: 983 ESERKPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKPTDENP----------CGFDSEC 1032
+ E P YK+I N + I +I+ + C C + C +D +
Sbjct: 942 DGEPCPEDYKYISENCETSTMNI-DRNITHLQHCTCVDDCSSSNCLCGQLSIRCWYDKDG 1000
Query: 1033 --------LNRMLMFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTDGKGWGLVAKRDIR 1084
+ L+FEC+ Q C C+N+ ++ +T GWG+ A + I
Sbjct: 1001 RLLQEFNKIEPPLIFECN-QACSCWRNCKNRVVQSGIKVRLQLYRTAKMGWGVRALQTIP 1059
Query: 1085 KGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTID-KD---RIIDAGPKGNYSRFM 1140
+G F+ EYVGELI + E R E+D Y+ +D KD IDA GN SRF+
Sbjct: 1060 QGTFICEYVGELISDAEADVR-----EDD---SYLFDLDNKDGEVYCIDARYYGNISRFI 1111
Query: 1141 NHSCQPNCETLK-WTVNGD---TRVGLFAVCDIPAGTELTFNYNLDCLGNEKT---VCRC 1193
NH C PN ++ + ++ D R+ F+ DI G EL F+Y D + K+ C+C
Sbjct: 1112 NHLCDPNIIPVRVFMLHQDLRFPRIAFFSSRDIRTGEELGFDYG-DRFWDIKSKYFTCQC 1170
Query: 1194 GASNC 1198
G+ C
Sbjct: 1171 GSEKC 1175
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 79.0 bits (193), Expect = 3e-14
Identities = 50/130 (38%), Positives = 65/130 (50%), Gaps = 2/130 (1%)
Query: 1074 GWGLVAKRDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRIIDAGPK 1133
G GL KR+I GE V EY G +I R K I YM +D ++DA
Sbjct: 2586 GRGLFCKRNIDAGEMVIEYSGIVIRSVLTDKREKFYDGKGIG-CYMFRMDDFDVVDATMH 2644
Query: 1134 GNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCL-GNEKTVCR 1192
GN +RF+NHSC+PNC + V G + +FA+ I G ELT++Y + K C
Sbjct: 2645 GNAARFINHSCEPNCFSRVIHVEGQKHIVIFALRRILRGEELTYDYKFPIEDASNKLPCN 2704
Query: 1193 CGASNCSGFL 1202
CGA C FL
Sbjct: 2705 CGAKRCRRFL 2714
Score = 47.8 bits (112), Expect = 7e-05
Identities = 41/142 (28%), Positives = 52/142 (36%), Gaps = 18/142 (12%)
Query: 669 VCQLCEKPG--SLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSCFVCKESKTD 726
VC LC G L+ C+ CC FH CL + RP + + C C VC
Sbjct: 1203 VCLLCASKGLHELVFCQ-VCCDPFHPFCLEEAERPLPQHHDTWCCRRCKFCHVCGRKGRG 1261
Query: 727 VKRCV-VTQCGKFYHEACV-KKYPLTVFESRGFRCPLH-SCVSCHASNPSNPRPSK---- 779
K + +C YH AC+ YP +R R H C +C P K
Sbjct: 1262 SKHLLECERCRHAYHPACLGPSYP-----TRATRKRRHWICSACVRCKSCGATPGKNWDV 1316
Query: 780 ---GKMMRCVRCPVAYHSGDAC 798
G C RC Y G+ C
Sbjct: 1317 EWSGDYSLCPRCTQLYEKGNYC 1338
Score = 35.0 bits (79), Expect = 0.49
Identities = 18/50 (36%), Positives = 23/50 (46%), Gaps = 10/50 (20%)
Query: 833 WCFVCSKGGS----LLCCESCPAAFHPDCLNIEMPDGS------WFCNDC 872
+C VC + G LL CE C A+HP CL P + W C+ C
Sbjct: 1251 FCHVCGRKGRGSKHLLECERCRHAYHPACLGPSYPTRATRKRRHWICSAC 1300
Score = 32.0 bits (71), Expect = 4.2
Identities = 20/60 (33%), Positives = 26/60 (43%), Gaps = 10/60 (16%)
Query: 1242 CFRCGDGG--QLVLCDRKFCTKAYHLSCLGLGKRPFGKWECPWHHCDVCGKPSTSFCHLC 1299
C C G +LV C + C +H CL +RP P HH C + FCH+C
Sbjct: 1204 CLLCASKGLHELVFC--QVCCDPFHPFCLEEAERPL-----PQHHDTWCCR-RCKFCHVC 1255
>gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo
sapiens]
Length = 4911
Score = 78.6 bits (192), Expect = 4e-14
Identities = 46/127 (36%), Positives = 65/127 (51%), Gaps = 2/127 (1%)
Query: 1073 KGWGLVAKRDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRIIDAGP 1132
+G GL A RDI K V EY+G +I E R + +E+ YM +D D +IDA
Sbjct: 4781 QGLGLYAARDIEKHTMVIEYIGTII-RNEVANRKEKLYESQNRGVYMFRMDNDHVIDATL 4839
Query: 1133 KGNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNE-KTVC 1191
G +R++NHSC PNC T ++ + + I G EL ++Y D ++ K C
Sbjct: 4840 TGGPARYINHSCAPNCVAEVVTFERGHKIIISSSRRIQKGEELCYDYKFDFEDDQHKIPC 4899
Query: 1192 RCGASNC 1198
CGA NC
Sbjct: 4900 HCGAVNC 4906
Score = 50.1 bits (118), Expect = 1e-05
Identities = 40/139 (28%), Positives = 58/139 (41%), Gaps = 18/139 (12%)
Query: 664 AKKEYVCQLCEKPGSLL---LCEGPCCGAFHLACLGLSRRPEGR--FTCSECASGIHSCF 718
+K++ C +C+ PG LL C C +H CL ++ P R + C EC C
Sbjct: 338 SKEDANCAVCDSPGDLLDQFFCT-TCGQHYHGMCLDIAVTPLKRAGWQCPECKV----CQ 392
Query: 719 VCKESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCP-LHSCVSCHASNPSNPRP 777
CK+S D K V C K YH C++ +V + G++C C+ C R
Sbjct: 393 NCKQSGEDSKMLVCDTCDKGYHTFCLQPVMKSV-PTNGWKCKNCRICIEC------GTRS 445
Query: 778 SKGKMMRCVRCPVAYHSGD 796
S C+ C Y D
Sbjct: 446 SSQWHHNCLICDNCYQQQD 464
Score = 43.5 bits (101), Expect = 0.001
Identities = 42/185 (22%), Positives = 64/185 (34%), Gaps = 35/185 (18%)
Query: 717 CFVCKE--SKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSN 774
C VC + + +QCG+ YH CV V S+G+RC C C A +
Sbjct: 960 CVVCGSFGQGAEGRLLACSQCGQCYHPYCVSIKITKVVLSKGWRC--LECTVCEACGKAT 1017
Query: 775 PRPSKGKMMRCVRCPVAYHSGDACLAAGCSVIASNS------IICTAHFTARKGKRHHAH 828
G+++ C C ++YH+ CL + + C G R
Sbjct: 1018 ---DPGRLLLCDDCDISYHT--YCLDPPLQTVPKGGWKCKWCVWCRHCGATSAGLRCEWQ 1072
Query: 829 VNVSWCFVCSKGGS-------------LLCCESCPAAFHPDCLNI-------EMPDGSWF 868
N + C C+ S +L C C H C N+ + D +
Sbjct: 1073 NNYTQCAPCASLSSCPVCYRNYREEDLILQCRQCDRWMHAVCQNLNTEEEVENVADIGFD 1132
Query: 869 CNDCR 873
C+ CR
Sbjct: 1133 CSMCR 1137
Score = 38.5 bits (88), Expect = 0.044
Identities = 27/86 (31%), Positives = 38/86 (44%), Gaps = 5/86 (5%)
Query: 1240 DECFRCGDGGQLVLCDRKFCTKAYHLSCLG--LGKRPFGKWECPW-HHCDVCGKPSTSFC 1296
+ C + D G+L+LCD C +YH CL L P G W+C W C CG S
Sbjct: 1011 EACGKATDPGRLLLCDD--CDISYHTYCLDPPLQTVPKGGWKCKWCVWCRHCGATSAGLR 1068
Query: 1297 HLCPNSFCKEHQDGTAFSCTPDGRSY 1322
N++ + + SC R+Y
Sbjct: 1069 CEWQNNYTQCAPCASLSSCPVCYRNY 1094
Score = 34.3 bits (77), Expect = 0.84
Identities = 38/166 (22%), Positives = 52/166 (31%), Gaps = 23/166 (13%)
Query: 717 CFVCKESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPR 776
C CK +K C +C + YH C + F+ H + C P
Sbjct: 285 CAFCKHLGATIK-CCEEKCTQMYHYPCAAG-------AGTFQDFSHIFLLCPEHIDQAPE 336
Query: 777 PSKGKMMRCVRCPVAYHSGDACLAAGCSVIASNSIICTAHFTARKGKRHHAHVNVSWCFV 836
SK C V GD C+ + KR A C V
Sbjct: 337 RSKED----ANCAVCDSPGDLLDQFFCTTCGQHYHGMCLDIAVTPLKR--AGWQCPECKV 390
Query: 837 CS------KGGSLLCCESCPAAFHPDCLNIEM---PDGSWFCNDCR 873
C + +L C++C +H CL M P W C +CR
Sbjct: 391 CQNCKQSGEDSKMLVCDTCDKGYHTFCLQPVMKSVPTNGWKCKNCR 436
Score = 33.1 bits (74), Expect = 1.9
Identities = 22/60 (36%), Positives = 28/60 (46%), Gaps = 10/60 (16%)
Query: 1235 KRQSED-ECFRCGDGGQLVLCDRKFCTKA---YHLSCLGLGKRPFGK--WECPWHHCDVC 1288
+R ED C C G L+ D+ FCT YH CL + P + W+CP C VC
Sbjct: 336 ERSKEDANCAVCDSPGDLL--DQFFCTTCGQHYHGMCLDIAVTPLKRAGWQCP--ECKVC 391
Score = 33.1 bits (74), Expect = 1.9
Identities = 22/88 (25%), Positives = 33/88 (37%), Gaps = 23/88 (26%)
Query: 1242 CFRCGDGGQLVLCDRKFCTKAYHLSCLG--LGKRPFGKWECP---------------WH- 1283
C + G+ ++++CD C K YH CL + P W+C WH
Sbjct: 394 CKQSGEDSKMLVCDT--CDKGYHTFCLQPVMKSVPTNGWKCKNCRICIECGTRSSSQWHH 451
Query: 1284 ---HCDVCGKPSTSFCHLCPNSFCKEHQ 1308
CD C + + C C + E Q
Sbjct: 452 NCLICDNCYQQQDNLCPFCGKCYHPELQ 479
>gi|224465233 euchromatic histone-lysine N-methyltransferase 1 isoform
1 [Homo sapiens]
Length = 1298
Score = 78.2 bits (191), Expect = 5e-14
Identities = 74/264 (28%), Positives = 114/264 (43%), Gaps = 39/264 (14%)
Query: 983 ESERKPPPYKHIKVNKPYGKVQI--------YTADISEIPKCNCKPTDENP-CGFDSE-- 1031
+SE P YK++ N + I Y I + NC + C +D +
Sbjct: 1030 DSEPCPSNYKYVSQNCVTSPMNIDRNITHLQYCVCIDDCSSSNCMCGQLSMRCWYDKDGR 1089
Query: 1032 ------CLNRMLMFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTDGKGWGLVAKRDIRK 1085
L+FEC+ C C+N+ ++ +T GWG+ + +DI
Sbjct: 1090 LLPEFNMAEPPLIFECN-HACSCWRNCRNRVVQNGLRARLQLYRTRDMGWGVRSLQDIPP 1148
Query: 1086 GEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKD---RIIDAGPKGNYSRFMNH 1142
G FV EYVGELI + E R + ++ D+ +KD IDA GN SRF+NH
Sbjct: 1149 GTFVCEYVGELISDSEADVREEDSYLFDLD-------NKDGEVYCIDARFYGNVSRFINH 1201
Query: 1143 SCQPNCETLK-WTVNGD---TRVGLFAVCDIPAGTELTFNYN---LDCLGNEKTVCRCGA 1195
C+PN ++ + + D R+ F+ I AG +L F+Y D G + CRCG+
Sbjct: 1202 HCEPNLVPVRVFMAHQDLRFPRIAFFSTRLIEAGEQLGFDYGERFWDIKG-KLFSCRCGS 1260
Query: 1196 SNC---SGFLGDRPKTSTTLSSEE 1216
C S L R ++ + E+
Sbjct: 1261 PKCRHSSAALAQRQASAAQEAQED 1284
>gi|4504191 mutS homolog 6 [Homo sapiens]
Length = 1360
Score = 72.0 bits (175), Expect = 4e-12
Identities = 48/166 (28%), Positives = 81/166 (48%), Gaps = 12/166 (7%)
Query: 220 YNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEK 279
++ GDLVW+K+ GYPWWPC+V P ++ + KG KS R HVQFF D+P R W+ ++
Sbjct: 90 FSPGDLVWAKMEGYPWWPCLVYNHPFDGTFIREKG--KSVR-VHVQFFDDSPTRGWVSKR 146
Query: 280 SLVAFEGEGQFEKLCQESAKQAPTKAEKIKLLKPISGKLRAQWEMGIVQAEEAA----SM 335
L + G +E+ K + K ++L+ + A + I + E A S
Sbjct: 147 LLKPYTGSKS-----KEAQKGGHFYSAKPEILRAMQRADEALNKDKIKRLELAVCDEPSE 201
Query: 336 SVEERKAKFTFLYVGDQLHLNPQVAKEAGIAAESLGEMAESSGVSE 381
EE + + YV D+ + ++ E + ++ G S + +
Sbjct: 202 PEEEEEMEVGTTYVTDKSEEDNEIESEEEVQPKTQGSRRSSRQIKK 247
Score = 35.0 bits (79), Expect = 0.49
Identities = 25/124 (20%), Positives = 47/124 (37%), Gaps = 8/124 (6%)
Query: 882 DIIWVKLGNYRWWPAEVCHPKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPY-- 939
D++W K+ Y WWP V + I++ + FF S W + + PY
Sbjct: 94 DLVWAKMEGYPWWPCLVYNHPFDGTFIREKGKSVRVHVQFFDDSPTRGWVSKRLLKPYTG 153
Query: 940 ---MEGDRGSRYQGVRGIGRVFKNALQEAEARFREIKLQREARETQESERKPPPYKHIKV 996
E +G + + A+Q A+ + K++R + +P + ++V
Sbjct: 154 SKSKEAQKGGHFYSAK---PEILRAMQRADEALNKDKIKRLELAVCDEPSEPEEEEEMEV 210
Query: 997 NKPY 1000
Y
Sbjct: 211 GTTY 214
>gi|94721344 zinc finger, CW type with PWWP domain 1 [Homo sapiens]
Length = 648
Score = 65.5 bits (158), Expect = 3e-10
Identities = 50/193 (25%), Positives = 80/193 (41%), Gaps = 19/193 (9%)
Query: 210 TGRDKD-HLLKYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKS-ARQYHVQFF 267
TG + D Y G ++W+K GYPWWP M+ +DP L Y S +YHV FF
Sbjct: 304 TGLESDVAYASYIPGSIIWAKQYGYPWWPGMIESDPDLGEYFLFTSHLDSLPSKYHVTFF 363
Query: 268 GDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQAPTKAEKIKLLKPISGKLRAQWEMGIV 327
G+ RAWI L F++L E + ++K + + ++
Sbjct: 364 GETVSRAWIPVNML------KNFQELSLE-----------LSVMKKRRNDCSQKLGVALM 406
Query: 328 QAEEAASMSVEERKAKFTFLYVGDQLHLNPQVAKEAGIAAESLGEMAESSGVSEEAAENP 387
A+EA +S++ER F F + + N + S G E EE +
Sbjct: 407 MAQEAEQISIQERVNLFGFWSRFNGSNSNGERKDLQLSGLNSPGSCLEKKEKEEELEKEE 466
Query: 388 KSVREECIPMKRR 400
+ +P+++R
Sbjct: 467 GEKTDPILPIRKR 479
>gi|24308089 chromodomain helicase DNA binding protein 5 [Homo
sapiens]
Length = 1954
Score = 62.4 bits (150), Expect = 3e-09
Identities = 46/143 (32%), Positives = 66/143 (46%), Gaps = 17/143 (11%)
Query: 1218 GKKTKKKTRRRRAK-GEG-KRQSEDECFRCGDGGQLVLCDRKFCTKAYHLSCLG--LGKR 1273
GKK+K++ +++R G+G + +D C C GG+++LCD C +AYHL CL L K
Sbjct: 320 GKKSKRRRKKKRIDDGDGYETDHQDYCEVCQQGGEIILCDT--CPRAYHLVCLDPELEKA 377
Query: 1274 PFGKWECPWHHCDVCG---KPSTSFCHLCPNSFCKEHQDGTAFS--CTPDGRSYCCEHDL 1328
P GKW CP HC+ G +P +E D F C G CC+
Sbjct: 378 PEGKWSCP--HCEKEGIQWEPKDDDDEEEEGGCEEEEDDHMEFCRVCKDGGELLCCDACP 435
Query: 1329 GAASVRSTKTEKPPPEPGKPKGK 1351
+ + PP P P G+
Sbjct: 436 SSYHLHCLN----PPLPEIPNGE 454
Score = 56.2 bits (134), Expect = 2e-07
Identities = 21/46 (45%), Positives = 31/46 (67%), Gaps = 3/46 (6%)
Query: 830 NVSWCFVCSKGGSLLCCESCPAAFHPDCLN---IEMPDGSWFCNDC 872
++ +C VC GG LLCC++CP+++H CLN E+P+G W C C
Sbjct: 415 HMEFCRVCKDGGELLCCDACPSSYHLHCLNPPLPEIPNGEWLCPRC 460
Score = 50.8 bits (120), Expect = 9e-06
Identities = 50/199 (25%), Positives = 77/199 (38%), Gaps = 59/199 (29%)
Query: 629 SDSPGDEPSESPYESAD----ETQTEVSVS-SKKSER-----------GVTAKKEYVCQL 672
S S DE ES ++SA ++E S + KKS+R G + C++
Sbjct: 289 SSSEEDEREESDFDSASIHSASVRSECSAALGKKSKRRRKKKRIDDGDGYETDHQDYCEV 348
Query: 673 CEKPGSLLLCEGPCCGAFHLACLG--LSRRPEGRFTCSECA------------------- 711
C++ G ++LC+ C A+HL CL L + PEG+++C C
Sbjct: 349 CQQGGEIILCD-TCPRAYHLVCLDPELEKAPEGKWSCPHCEKEGIQWEPKDDDDEEEEGG 407
Query: 712 ------SGIHSCFVCKESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCV 765
+ C VCK+ + C YH C+ PL + + CP +C
Sbjct: 408 CEEEEDDHMEFCRVCKDGG---ELLCCDACPSSYHLHCLNP-PLPEIPNGEWLCPRCTC- 462
Query: 766 SCHASNPSNPRPSKGKMMR 784
P KGK+ R
Sbjct: 463 ----------PPLKGKVQR 471
Score = 49.3 bits (116), Expect = 3e-05
Identities = 18/43 (41%), Positives = 28/43 (65%), Gaps = 3/43 (6%)
Query: 833 WCFVCSKGGSLLCCESCPAAFHPDCLNIEM---PDGSWFCNDC 872
+C VC +GG ++ C++CP A+H CL+ E+ P+G W C C
Sbjct: 345 YCEVCQQGGEIILCDTCPRAYHLVCLDPELEKAPEGKWSCPHC 387
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.132 0.410
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 59,218,491
Number of Sequences: 37866
Number of extensions: 2997061
Number of successful extensions: 14728
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 164
Number of HSP's successfully gapped in prelim test: 334
Number of HSP's that attempted gapping in prelim test: 12895
Number of HSP's gapped (non-prelim): 1904
length of query: 1365
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1250
effective length of database: 13,892,928
effective search space: 17366160000
effective search space used: 17366160000
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.