Guide to the Human Genome
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Search of human proteins with 14165439

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|14165439 heterogeneous nuclear ribonucleoprotein K isoform a
[Homo sapiens]
         (464 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|14165439 heterogeneous nuclear ribonucleoprotein K isoform a ...   955   0.0  
gi|14165437 heterogeneous nuclear ribonucleoprotein K isoform a ...   955   0.0  
gi|14165435 heterogeneous nuclear ribonucleoprotein K isoform b ...   943   0.0  
gi|193083110 poly(rC) binding protein 2 isoform e [Homo sapiens]      154   1e-37
gi|193083108 poly(rC) binding protein 2 isoform d [Homo sapiens]      154   1e-37
gi|14141166 poly(rC) binding protein 2 isoform b [Homo sapiens]       154   2e-37
gi|14141168 poly(rC) binding protein 2 isoform a [Homo sapiens]       154   2e-37
gi|222352151 poly(rC) binding protein 1 [Homo sapiens]                138   1e-32
gi|193083114 poly(rC) binding protein 2 isoform g [Homo sapiens]      106   4e-23
gi|193083112 poly(rC) binding protein 2 isoform f [Homo sapiens]      106   4e-23
gi|148833484 poly(rC) binding protein 2 isoform c [Homo sapiens]      106   4e-23
gi|194306631 poly(rC) binding protein 3 isoform 1 [Homo sapiens]      106   5e-23
gi|14670373 poly(rC) binding protein 4 isoform c [Homo sapiens]       100   5e-21
gi|14670369 poly(rC) binding protein 4 isoform c [Homo sapiens]       100   5e-21
gi|194306633 poly(rC) binding protein 3 isoform 2 [Homo sapiens]       94   3e-19
gi|56549651 neuro-oncological ventral antigen 1 isoform 2 [Homo ...    70   3e-12
gi|5902724 neuro-oncological ventral antigen 2 [Homo sapiens]          70   3e-12
gi|154355000 KH-type splicing regulatory protein [Homo sapiens]        70   4e-12
gi|17402900 far upstream element-binding protein [Homo sapiens]        67   4e-11
gi|56549653 neuro-oncological ventral antigen 1 isoform 1 [Homo ...    64   4e-10
gi|100816392 far upstream element (FUSE) binding protein 3 [Homo...    63   5e-10
gi|238624257 insulin-like growth factor 2 mRNA binding protein 1...    59   9e-09
gi|9966803 poly(rC) binding protein 4 isoform a [Homo sapiens]         59   1e-08
gi|56237027 insulin-like growth factor 2 mRNA binding protein 1 ...    58   2e-08
gi|30795212 insulin-like growth factor 2 mRNA binding protein 3 ...    56   6e-08
gi|5730027 KH domain containing, RNA binding, signal transductio...    55   1e-07
gi|56118219 insulin-like growth factor 2 mRNA binding protein 2 ...    54   2e-07
gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo s...    54   4e-07
gi|156151396 heterogeneous nuclear ribonucleoprotein R isoform 3...    52   1e-06
gi|156151394 heterogeneous nuclear ribonucleoprotein R isoform 1...    52   1e-06

>gi|14165439 heterogeneous nuclear ribonucleoprotein K isoform a
           [Homo sapiens]
          Length = 464

 Score =  955 bits (2468), Expect = 0.0
 Identities = 464/464 (100%), Positives = 464/464 (100%)

Query: 1   METEQPEETFPNTETNGEFGKRPAEDMEEEQAFKRSRNTDEMVELRILLQSKNAGAVIGK 60
           METEQPEETFPNTETNGEFGKRPAEDMEEEQAFKRSRNTDEMVELRILLQSKNAGAVIGK
Sbjct: 1   METEQPEETFPNTETNGEFGKRPAEDMEEEQAFKRSRNTDEMVELRILLQSKNAGAVIGK 60

Query: 61  GGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKIIPTLEEGLQLPSPTAT 120
           GGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKIIPTLEEGLQLPSPTAT
Sbjct: 61  GGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKIIPTLEEGLQLPSPTAT 120

Query: 121 SQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKL 180
           SQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKL
Sbjct: 121 SQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKL 180

Query: 181 FQECCPHSTDRVVLIGGKPDRVVECIKIILDLISESPIKGRAQPYDPNFYDETYDYGGFT 240
           FQECCPHSTDRVVLIGGKPDRVVECIKIILDLISESPIKGRAQPYDPNFYDETYDYGGFT
Sbjct: 181 FQECCPHSTDRVVLIGGKPDRVVECIKIILDLISESPIKGRAQPYDPNFYDETYDYGGFT 240

Query: 241 MMFDDRRGRPVGFPMRGRGGFDRMPPGRGGRPMPPSRRDYDDMSPRRGPPPPPPGRGGRG 300
           MMFDDRRGRPVGFPMRGRGGFDRMPPGRGGRPMPPSRRDYDDMSPRRGPPPPPPGRGGRG
Sbjct: 241 MMFDDRRGRPVGFPMRGRGGFDRMPPGRGGRPMPPSRRDYDDMSPRRGPPPPPPGRGGRG 300

Query: 301 GSRARNLPLPPPPPPRGGDLMAYDRRGRPGDRYDGMVGFSADETWDSAIDTWSPSEWQMA 360
           GSRARNLPLPPPPPPRGGDLMAYDRRGRPGDRYDGMVGFSADETWDSAIDTWSPSEWQMA
Sbjct: 301 GSRARNLPLPPPPPPRGGDLMAYDRRGRPGDRYDGMVGFSADETWDSAIDTWSPSEWQMA 360

Query: 361 YEPQGGSGYDYSYAGGRGSYGDLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGAS 420
           YEPQGGSGYDYSYAGGRGSYGDLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGAS
Sbjct: 361 YEPQGGSGYDYSYAGGRGSYGDLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGAS 420

Query: 421 IKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQYADVEGF 464
           IKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQYADVEGF
Sbjct: 421 IKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQYADVEGF 464


>gi|14165437 heterogeneous nuclear ribonucleoprotein K isoform a
           [Homo sapiens]
          Length = 464

 Score =  955 bits (2468), Expect = 0.0
 Identities = 464/464 (100%), Positives = 464/464 (100%)

Query: 1   METEQPEETFPNTETNGEFGKRPAEDMEEEQAFKRSRNTDEMVELRILLQSKNAGAVIGK 60
           METEQPEETFPNTETNGEFGKRPAEDMEEEQAFKRSRNTDEMVELRILLQSKNAGAVIGK
Sbjct: 1   METEQPEETFPNTETNGEFGKRPAEDMEEEQAFKRSRNTDEMVELRILLQSKNAGAVIGK 60

Query: 61  GGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKIIPTLEEGLQLPSPTAT 120
           GGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKIIPTLEEGLQLPSPTAT
Sbjct: 61  GGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKIIPTLEEGLQLPSPTAT 120

Query: 121 SQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKL 180
           SQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKL
Sbjct: 121 SQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKL 180

Query: 181 FQECCPHSTDRVVLIGGKPDRVVECIKIILDLISESPIKGRAQPYDPNFYDETYDYGGFT 240
           FQECCPHSTDRVVLIGGKPDRVVECIKIILDLISESPIKGRAQPYDPNFYDETYDYGGFT
Sbjct: 181 FQECCPHSTDRVVLIGGKPDRVVECIKIILDLISESPIKGRAQPYDPNFYDETYDYGGFT 240

Query: 241 MMFDDRRGRPVGFPMRGRGGFDRMPPGRGGRPMPPSRRDYDDMSPRRGPPPPPPGRGGRG 300
           MMFDDRRGRPVGFPMRGRGGFDRMPPGRGGRPMPPSRRDYDDMSPRRGPPPPPPGRGGRG
Sbjct: 241 MMFDDRRGRPVGFPMRGRGGFDRMPPGRGGRPMPPSRRDYDDMSPRRGPPPPPPGRGGRG 300

Query: 301 GSRARNLPLPPPPPPRGGDLMAYDRRGRPGDRYDGMVGFSADETWDSAIDTWSPSEWQMA 360
           GSRARNLPLPPPPPPRGGDLMAYDRRGRPGDRYDGMVGFSADETWDSAIDTWSPSEWQMA
Sbjct: 301 GSRARNLPLPPPPPPRGGDLMAYDRRGRPGDRYDGMVGFSADETWDSAIDTWSPSEWQMA 360

Query: 361 YEPQGGSGYDYSYAGGRGSYGDLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGAS 420
           YEPQGGSGYDYSYAGGRGSYGDLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGAS
Sbjct: 361 YEPQGGSGYDYSYAGGRGSYGDLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGAS 420

Query: 421 IKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQYADVEGF 464
           IKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQYADVEGF
Sbjct: 421 IKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQYADVEGF 464


>gi|14165435 heterogeneous nuclear ribonucleoprotein K isoform b
           [Homo sapiens]
          Length = 463

 Score =  943 bits (2438), Expect = 0.0
 Identities = 458/459 (99%), Positives = 459/459 (100%)

Query: 1   METEQPEETFPNTETNGEFGKRPAEDMEEEQAFKRSRNTDEMVELRILLQSKNAGAVIGK 60
           METEQPEETFPNTETNGEFGKRPAEDMEEEQAFKRSRNTDEMVELRILLQSKNAGAVIGK
Sbjct: 1   METEQPEETFPNTETNGEFGKRPAEDMEEEQAFKRSRNTDEMVELRILLQSKNAGAVIGK 60

Query: 61  GGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKIIPTLEEGLQLPSPTAT 120
           GGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKIIPTLEEGLQLPSPTAT
Sbjct: 61  GGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKIIPTLEEGLQLPSPTAT 120

Query: 121 SQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKL 180
           SQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKL
Sbjct: 121 SQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKL 180

Query: 181 FQECCPHSTDRVVLIGGKPDRVVECIKIILDLISESPIKGRAQPYDPNFYDETYDYGGFT 240
           FQECCPHSTDRVVLIGGKPDRVVECIKIILDLISESPIKGRAQPYDPNFYDETYDYGGFT
Sbjct: 181 FQECCPHSTDRVVLIGGKPDRVVECIKIILDLISESPIKGRAQPYDPNFYDETYDYGGFT 240

Query: 241 MMFDDRRGRPVGFPMRGRGGFDRMPPGRGGRPMPPSRRDYDDMSPRRGPPPPPPGRGGRG 300
           MMFDDRRGRPVGFPMRGRGGFDRMPPGRGGRPMPPSRRDYDDMSPRRGPPPPPPGRGGRG
Sbjct: 241 MMFDDRRGRPVGFPMRGRGGFDRMPPGRGGRPMPPSRRDYDDMSPRRGPPPPPPGRGGRG 300

Query: 301 GSRARNLPLPPPPPPRGGDLMAYDRRGRPGDRYDGMVGFSADETWDSAIDTWSPSEWQMA 360
           GSRARNLPLPPPPPPRGGDLMAYDRRGRPGDRYDGMVGFSADETWDSAIDTWSPSEWQMA
Sbjct: 301 GSRARNLPLPPPPPPRGGDLMAYDRRGRPGDRYDGMVGFSADETWDSAIDTWSPSEWQMA 360

Query: 361 YEPQGGSGYDYSYAGGRGSYGDLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGAS 420
           YEPQGGSGYDYSYAGGRGSYGDLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGAS
Sbjct: 361 YEPQGGSGYDYSYAGGRGSYGDLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGAS 420

Query: 421 IKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQYA 459
           IKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQY+
Sbjct: 421 IKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQYS 459


>gi|193083110 poly(rC) binding protein 2 isoform e [Homo sapiens]
          Length = 361

 Score =  154 bits (390), Expect = 1e-37
 Identities = 119/410 (29%), Positives = 180/410 (43%), Gaps = 81/410 (19%)

Query: 45  LRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKI 104
           +R+L+  K  G++IGK G+++K +R +  A +++ + + PERI++++     I +    I
Sbjct: 16  IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMI 75

Query: 105 IPTLEEGLQ--LPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGV 162
           I  LEE +   + + TA S+ P+                     LRL++  S  G +IG 
Sbjct: 76  IDKLEEDISSSMTNSTAASRPPVT--------------------LRLVVPASQCGSLIGK 115

Query: 163 KGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRVVECIKIILDLISESPIKGRA 222
            G KIKE+RE+T   +++  +  P+ST+R + I G P  ++EC+K I  ++ ESP KG  
Sbjct: 116 GGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVT 175

Query: 223 QPYDPNFYDETYDYGGFTMMFDDRRGRPVGFPMRGRGGFDRMPPGRGGRPMPPSRRDYDD 282
            PY P                     +P   P+   GG DR   G      P +      
Sbjct: 176 IPYRP---------------------KPSSSPVIFAGGQDRYSTGSDSASFPHTT----- 209

Query: 283 MSPRRGPPPPPPGRGGRGGSRARNLPLPPPPPPRGGDLMAYDRRGRPGDRYDGMVGFSAD 342
                              S   N  L  PP      L AY           G       
Sbjct: 210 ------------------PSMCLNPDLEGPP------LEAY--------TIQGQYAIPQP 237

Query: 343 ETWDSAIDTWSPSEWQMAYEPQGGSGYDYSYAGGRGSYG-DLGGPIITTQVTIPKDLAGS 401
           +           S + M +   G SG + S    +G +G D      + ++TIP DL G 
Sbjct: 238 DLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWGLDASAQTTSHELTIPNDLIGC 297

Query: 402 IIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYLL 451
           IIG+ G +I +IR  SGA IKI  P+EGS DR +TITG+   I  AQYL+
Sbjct: 298 IIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLI 347



 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 22/76 (28%), Positives = 41/76 (53%), Gaps = 3/76 (3%)

Query: 140 GSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKP 199
           G +    +RLL+H    G IIG KG  +K++RE +   I + +  CP   +R++ + G  
Sbjct: 9   GLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCP---ERIITLAGPT 65

Query: 200 DRVVECIKIILDLISE 215
           + + +   +I+D + E
Sbjct: 66  NAIFKAFAMIIDKLEE 81



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 23/58 (39%), Positives = 36/58 (62%), Gaps = 2/58 (3%)

Query: 400 GSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQ 457
           GSIIGK G+ +K++R ESGA I I E      +RIIT+ G  + I  A  ++ + +++
Sbjct: 26  GSIIGKKGESVKKMREESGARINISE--GNCPERIITLAGPTNAIFKAFAMIIDKLEE 81



 Score = 39.7 bits (91), Expect = 0.006
 Identities = 28/90 (31%), Positives = 46/90 (51%), Gaps = 7/90 (7%)

Query: 43  VELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGP---ERILSISADIETIGE 99
           V LR+++ +   G++IGKGG  IK +R    A V V     P   ER ++I+   ++I E
Sbjct: 98  VTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIE 157

Query: 100 ILKKIIPTLEE----GLQLPSPTATSQLPL 125
            +K+I   + E    G+ +P     S  P+
Sbjct: 158 CVKQICVVMLESPPKGVTIPYRPKPSSSPV 187


>gi|193083108 poly(rC) binding protein 2 isoform d [Homo sapiens]
          Length = 365

 Score =  154 bits (390), Expect = 1e-37
 Identities = 119/414 (28%), Positives = 183/414 (44%), Gaps = 85/414 (20%)

Query: 45  LRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKI 104
           +R+L+  K  G++IGK G+++K +R +  A +++ + + PERI++++     I +    I
Sbjct: 16  IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMI 75

Query: 105 IPTLEEGLQ--LPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGV 162
           I  LEE +   + + TA S+ P+                     LRL++  S  G +IG 
Sbjct: 76  IDKLEEDISSSMTNSTAASRPPVT--------------------LRLVVPASQCGSLIGK 115

Query: 163 KGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRVVECIK----IILDLISESPI 218
            G KIKE+RE+T   +++  +  P+ST+R + I G P  ++EC+K    ++L+ +S+SP 
Sbjct: 116 GGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPP 175

Query: 219 KGRAQPYDPNFYDETYDYGGFTMMFDDRRGRPVGFPMRGRGGFDRMPPGRGGRPMPPSRR 278
           KG   PY P                     +P   P+   GG DR   G      P +  
Sbjct: 176 KGVTIPYRP---------------------KPSSSPVIFAGGQDRYSTGSDSASFPHTT- 213

Query: 279 DYDDMSPRRGPPPPPPGRGGRGGSRARNLPLPPPPPPRGGDLMAYDRRGRPGDRYDGMVG 338
                                  S   N  L  PP      L AY           G   
Sbjct: 214 ----------------------PSMCLNPDLEGPP------LEAY--------TIQGQYA 237

Query: 339 FSADETWDSAIDTWSPSEWQMAYEPQGGSGYDYSYAGGRGSYG-DLGGPIITTQVTIPKD 397
               +           S + M +   G SG + S    +G +G D      + ++TIP D
Sbjct: 238 IPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWGLDASAQTTSHELTIPND 297

Query: 398 LAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYLL 451
           L G IIG+ G +I +IR  SGA IKI  P+EGS DR +TITG+   I  AQYL+
Sbjct: 298 LIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLI 351



 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 22/76 (28%), Positives = 41/76 (53%), Gaps = 3/76 (3%)

Query: 140 GSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKP 199
           G +    +RLL+H    G IIG KG  +K++RE +   I + +  CP   +R++ + G  
Sbjct: 9   GLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCP---ERIITLAGPT 65

Query: 200 DRVVECIKIILDLISE 215
           + + +   +I+D + E
Sbjct: 66  NAIFKAFAMIIDKLEE 81



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 23/58 (39%), Positives = 36/58 (62%), Gaps = 2/58 (3%)

Query: 400 GSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQ 457
           GSIIGK G+ +K++R ESGA I I E      +RIIT+ G  + I  A  ++ + +++
Sbjct: 26  GSIIGKKGESVKKMREESGARINISE--GNCPERIITLAGPTNAIFKAFAMIIDKLEE 81



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 26/78 (33%), Positives = 41/78 (52%), Gaps = 3/78 (3%)

Query: 43  VELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGP---ERILSISADIETIGE 99
           V LR+++ +   G++IGKGG  IK +R    A V V     P   ER ++I+   ++I E
Sbjct: 98  VTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIE 157

Query: 100 ILKKIIPTLEEGLQLPSP 117
            +K+I   + E L    P
Sbjct: 158 CVKQICVVMLETLSQSPP 175


>gi|14141166 poly(rC) binding protein 2 isoform b [Homo sapiens]
          Length = 362

 Score =  154 bits (389), Expect = 2e-37
 Identities = 120/411 (29%), Positives = 180/411 (43%), Gaps = 82/411 (19%)

Query: 45  LRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKI 104
           +R+L+  K  G++IGK G+++K +R +  A +++ + + PERI++++     I +    I
Sbjct: 16  IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMI 75

Query: 105 IPTLEEGLQ--LPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGV 162
           I  LEE +   + + TA S+ P+                     LRL++  S  G +IG 
Sbjct: 76  IDKLEEDISSSMTNSTAASRPPVT--------------------LRLVVPASQCGSLIGK 115

Query: 163 KGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRVVECIKIILDLISESPIKGRA 222
            G KIKE+RE+T   +++  +  P+ST+R + I G P  ++EC+K I  ++ ESP KG  
Sbjct: 116 GGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVT 175

Query: 223 QPYDPNFYDETYDYGGFTMMFDDRRGRPVGFPMRGRGGFDRMPPGRGGRPMPPSRRDYDD 282
            PY P                     +P   P+   GG DR   G      P +      
Sbjct: 176 IPYRP---------------------KPSSSPVIFAGGQDRYSTGSDSASFPHTT----- 209

Query: 283 MSPRRGPPPPPPGRGGRGGSRARNLPLPPPPPPRGGDLMAYDRRGRPGDRYDGMVGFSAD 342
                              S   N  L  PP      L AY           G       
Sbjct: 210 ------------------PSMCLNPDLEGPP------LEAY--------TIQGQYAIPQP 237

Query: 343 ETWDSAIDTWSPSEWQMAYEPQGGSGYDYSYAGGRGSYGDLGGPIITT--QVTIPKDLAG 400
           +           S + M +   G SG + S    +G +  L     TT  ++TIP DL G
Sbjct: 238 DLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLIG 297

Query: 401 SIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYLL 451
            IIG+ G +I +IR  SGA IKI  P+EGS DR +TITG+   I  AQYL+
Sbjct: 298 CIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLI 348



 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 22/76 (28%), Positives = 41/76 (53%), Gaps = 3/76 (3%)

Query: 140 GSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKP 199
           G +    +RLL+H    G IIG KG  +K++RE +   I + +  CP   +R++ + G  
Sbjct: 9   GLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCP---ERIITLAGPT 65

Query: 200 DRVVECIKIILDLISE 215
           + + +   +I+D + E
Sbjct: 66  NAIFKAFAMIIDKLEE 81



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 23/58 (39%), Positives = 36/58 (62%), Gaps = 2/58 (3%)

Query: 400 GSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQ 457
           GSIIGK G+ +K++R ESGA I I E      +RIIT+ G  + I  A  ++ + +++
Sbjct: 26  GSIIGKKGESVKKMREESGARINISE--GNCPERIITLAGPTNAIFKAFAMIIDKLEE 81



 Score = 39.7 bits (91), Expect = 0.006
 Identities = 28/90 (31%), Positives = 46/90 (51%), Gaps = 7/90 (7%)

Query: 43  VELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGP---ERILSISADIETIGE 99
           V LR+++ +   G++IGKGG  IK +R    A V V     P   ER ++I+   ++I E
Sbjct: 98  VTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIE 157

Query: 100 ILKKIIPTLEE----GLQLPSPTATSQLPL 125
            +K+I   + E    G+ +P     S  P+
Sbjct: 158 CVKQICVVMLESPPKGVTIPYRPKPSSSPV 187


>gi|14141168 poly(rC) binding protein 2 isoform a [Homo sapiens]
          Length = 366

 Score =  154 bits (389), Expect = 2e-37
 Identities = 120/415 (28%), Positives = 183/415 (44%), Gaps = 86/415 (20%)

Query: 45  LRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKI 104
           +R+L+  K  G++IGK G+++K +R +  A +++ + + PERI++++     I +    I
Sbjct: 16  IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMI 75

Query: 105 IPTLEEGLQ--LPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGV 162
           I  LEE +   + + TA S+ P+                     LRL++  S  G +IG 
Sbjct: 76  IDKLEEDISSSMTNSTAASRPPVT--------------------LRLVVPASQCGSLIGK 115

Query: 163 KGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRVVECIK----IILDLISESPI 218
            G KIKE+RE+T   +++  +  P+ST+R + I G P  ++EC+K    ++L+ +S+SP 
Sbjct: 116 GGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPP 175

Query: 219 KGRAQPYDPNFYDETYDYGGFTMMFDDRRGRPVGFPMRGRGGFDRMPPGRGGRPMPPSRR 278
           KG   PY P                     +P   P+   GG DR   G      P +  
Sbjct: 176 KGVTIPYRP---------------------KPSSSPVIFAGGQDRYSTGSDSASFPHTT- 213

Query: 279 DYDDMSPRRGPPPPPPGRGGRGGSRARNLPLPPPPPPRGGDLMAYDRRGRPGDRYDGMVG 338
                                  S   N  L  PP      L AY           G   
Sbjct: 214 ----------------------PSMCLNPDLEGPP------LEAY--------TIQGQYA 237

Query: 339 FSADETWDSAIDTWSPSEWQMAYEPQGGSGYDYSYAGGRGSYGDLGGPIITT--QVTIPK 396
               +           S + M +   G SG + S    +G +  L     TT  ++TIP 
Sbjct: 238 IPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPN 297

Query: 397 DLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYLL 451
           DL G IIG+ G +I +IR  SGA IKI  P+EGS DR +TITG+   I  AQYL+
Sbjct: 298 DLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLI 352



 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 22/76 (28%), Positives = 41/76 (53%), Gaps = 3/76 (3%)

Query: 140 GSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKP 199
           G +    +RLL+H    G IIG KG  +K++RE +   I + +  CP   +R++ + G  
Sbjct: 9   GLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCP---ERIITLAGPT 65

Query: 200 DRVVECIKIILDLISE 215
           + + +   +I+D + E
Sbjct: 66  NAIFKAFAMIIDKLEE 81



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 23/58 (39%), Positives = 36/58 (62%), Gaps = 2/58 (3%)

Query: 400 GSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQ 457
           GSIIGK G+ +K++R ESGA I I E      +RIIT+ G  + I  A  ++ + +++
Sbjct: 26  GSIIGKKGESVKKMREESGARINISE--GNCPERIITLAGPTNAIFKAFAMIIDKLEE 81



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 26/78 (33%), Positives = 41/78 (52%), Gaps = 3/78 (3%)

Query: 43  VELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGP---ERILSISADIETIGE 99
           V LR+++ +   G++IGKGG  IK +R    A V V     P   ER ++I+   ++I E
Sbjct: 98  VTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIE 157

Query: 100 ILKKIIPTLEEGLQLPSP 117
            +K+I   + E L    P
Sbjct: 158 CVKQICVVMLETLSQSPP 175


>gi|222352151 poly(rC) binding protein 1 [Homo sapiens]
          Length = 356

 Score =  138 bits (347), Expect = 1e-32
 Identities = 120/416 (28%), Positives = 185/416 (44%), Gaps = 97/416 (23%)

Query: 45  LRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKI 104
           +R+L+  K  G++IGK G+++K +R +  A +++ + + PERI++++     I +    I
Sbjct: 16  IRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGNCPERIITLTGPTNAIFKAFAMI 75

Query: 105 IPTLEEGLQ--LPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGV 162
           I  LEE +   + + TA S+ P+                     LRL++  +  G +IG 
Sbjct: 76  IDKLEEDINSSMTNSTAASRPPVT--------------------LRLVVPATQCGSLIGK 115

Query: 163 KGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRVVECIK----IILDLISESPI 218
            G KIKE+RE+T   +++  +  P+ST+R + I G P  V EC+K    ++L+ +S+SP 
Sbjct: 116 GGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGVPQSVTECVKQICLVMLETLSQSP- 174

Query: 219 KGRAQ--PYDPNFYDETYDYGGFTMMFDDRRGRPVGFPMRGRGGFDRMPPGRGGRPMPPS 276
           +GR    PY P                      P   P+   GG DR     G    P +
Sbjct: 175 QGRVMTIPYQP---------------------MPASSPVICAGGQDRCSDAAG---YPHA 210

Query: 277 RRDYDDMSPRRGPPPPPPGRGGRGGSRARNLPLPPPPPPRGGDLMAYDRRGRPGDRYDGM 336
             D +      GPP       G+        PL         DL   ++  R    +  M
Sbjct: 211 THDLE------GPPLDAYSIQGQHTIS----PL---------DLAKLNQVARQQSHFAMM 251

Query: 337 VGFSADETWDSAIDTWSPSEWQMAYEPQGGSGYDYSYAGGRGSYGDLGGPIITT-QVTIP 395
            G     T  + ID+ SP                      +G +  L     TT ++TIP
Sbjct: 252 HG----GTGFAGIDSSSPEV--------------------KGYWASLDASTQTTHELTIP 287

Query: 396 KDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYLL 451
            +L G IIG+ G  I +IR  SGA IKI  P+EGS  R +TITG+   I  AQYL+
Sbjct: 288 NNLIGCIIGRQGANINEIRQMSGAQIKIANPVEGSSGRQVTITGSAASISLAQYLI 343



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 22/76 (28%), Positives = 40/76 (52%), Gaps = 3/76 (3%)

Query: 140 GSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKP 199
           G +    +RLL+H    G IIG KG  +K +RE +   I + +  CP   +R++ + G  
Sbjct: 9   GLNVTLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGNCP---ERIITLTGPT 65

Query: 200 DRVVECIKIILDLISE 215
           + + +   +I+D + E
Sbjct: 66  NAIFKAFAMIIDKLEE 81



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 25/58 (43%), Positives = 37/58 (63%), Gaps = 2/58 (3%)

Query: 400 GSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQ 457
           GSIIGK G+ +K+IR ESGA I I E      +RIIT+TG  + I  A  ++ + +++
Sbjct: 26  GSIIGKKGESVKRIREESGARINISE--GNCPERIITLTGPTNAIFKAFAMIIDKLEE 81



 Score = 38.9 bits (89), Expect = 0.010
 Identities = 24/73 (32%), Positives = 40/73 (54%), Gaps = 3/73 (4%)

Query: 43  VELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGP---ERILSISADIETIGE 99
           V LR+++ +   G++IGKGG  IK +R    A V V     P   ER ++I+   +++ E
Sbjct: 98  VTLRLVVPATQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGVPQSVTE 157

Query: 100 ILKKIIPTLEEGL 112
            +K+I   + E L
Sbjct: 158 CVKQICLVMLETL 170


>gi|193083114 poly(rC) binding protein 2 isoform g [Homo sapiens]
          Length = 318

 Score =  106 bits (265), Expect = 4e-23
 Identities = 59/185 (31%), Positives = 101/185 (54%), Gaps = 22/185 (11%)

Query: 45  LRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKI 104
           +R+L+  K  G++IGK G+++K +R +  A +++ + + PERI++++     I +    I
Sbjct: 16  IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMI 75

Query: 105 IPTLEEGLQ--LPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGV 162
           I  LEE +   + + TA S+ P+                     LRL++  S  G +IG 
Sbjct: 76  IDKLEEDISSSMTNSTAASRPPVT--------------------LRLVVPASQCGSLIGK 115

Query: 163 KGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRVVECIKIILDLISESPIKGRA 222
            G KIKE+RE+T   +++  +  P+ST+R + I G P  ++EC+K I  ++ ESP KG  
Sbjct: 116 GGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVT 175

Query: 223 QPYDP 227
            PY P
Sbjct: 176 IPYRP 180



 Score = 68.9 bits (167), Expect = 9e-12
 Identities = 35/70 (50%), Positives = 45/70 (64%)

Query: 382 DLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQ 441
           D      + ++TIP DL G IIG+ G +I +IR  SGA IKI  P+EGS DR +TITG+ 
Sbjct: 235 DASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSA 294

Query: 442 DQIQNAQYLL 451
             I  AQYL+
Sbjct: 295 ASISLAQYLI 304



 Score = 49.3 bits (116), Expect = 7e-06
 Identities = 24/60 (40%), Positives = 37/60 (61%), Gaps = 1/60 (1%)

Query: 386 PIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKI-DEPLEGSEDRIITITGTQDQI 444
           P +T ++ +P    GS+IGKGG +IK+IR  +GA +++  + L  S +R ITI G    I
Sbjct: 96  PPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSI 155



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 53/196 (27%), Positives = 81/196 (41%), Gaps = 42/196 (21%)

Query: 43  VELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGP---ERILSISADIETIGE 99
           V LR+++ +   G++IGKGG  IK +R    A V V     P   ER ++I+   ++I E
Sbjct: 98  VTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIE 157

Query: 100 ILKKI-------------IP------------------TLEEGLQLPSPTATS--QLPLE 126
            +K+I             IP                  T++    +P P  T   QL ++
Sbjct: 158 CVKQICVVMLESPPKGVTIPYRPKPSSSPVIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQ 217

Query: 127 SDAVECLNYQHYKGSDFDCELRLLIHQ-----SLAGGIIGVKGAKIKELRENTQTTIKLF 181
                  +      +  D   +   H+      L G IIG +GAKI E+R+ +   IK+ 
Sbjct: 218 QSHFPMTHGNTGFSAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIA 277

Query: 182 QECCPHSTDRVVLIGG 197
                 STDR V I G
Sbjct: 278 NP-VEGSTDRQVTITG 292



 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 22/76 (28%), Positives = 41/76 (53%), Gaps = 3/76 (3%)

Query: 140 GSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKP 199
           G +    +RLL+H    G IIG KG  +K++RE +   I + +  CP   +R++ + G  
Sbjct: 9   GLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCP---ERIITLAGPT 65

Query: 200 DRVVECIKIILDLISE 215
           + + +   +I+D + E
Sbjct: 66  NAIFKAFAMIIDKLEE 81



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 23/58 (39%), Positives = 36/58 (62%), Gaps = 2/58 (3%)

Query: 400 GSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQ 457
           GSIIGK G+ +K++R ESGA I I E      +RIIT+ G  + I  A  ++ + +++
Sbjct: 26  GSIIGKKGESVKKMREESGARINISE--GNCPERIITLAGPTNAIFKAFAMIIDKLEE 81


>gi|193083112 poly(rC) binding protein 2 isoform f [Homo sapiens]
          Length = 335

 Score =  106 bits (265), Expect = 4e-23
 Identities = 59/189 (31%), Positives = 104/189 (55%), Gaps = 26/189 (13%)

Query: 45  LRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKI 104
           +R+L+  K  G++IGK G+++K +R +  A +++ + + PERI++++     I +    I
Sbjct: 16  IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMI 75

Query: 105 IPTLEEGLQ--LPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGV 162
           I  LEE +   + + TA S+ P+                     LRL++  S  G +IG 
Sbjct: 76  IDKLEEDISSSMTNSTAASRPPVT--------------------LRLVVPASQCGSLIGK 115

Query: 163 KGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRVVECIK----IILDLISESPI 218
            G KIKE+RE+T   +++  +  P+ST+R + I G P  ++EC+K    ++L+ +S+SP 
Sbjct: 116 GGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPP 175

Query: 219 KGRAQPYDP 227
           KG   PY P
Sbjct: 176 KGVTIPYRP 184



 Score = 74.7 bits (182), Expect = 2e-13
 Identities = 44/99 (44%), Positives = 58/99 (58%), Gaps = 2/99 (2%)

Query: 355 SEWQMAYEPQGGSGYDYSYAGGRGSYGDLGGPIITT--QVTIPKDLAGSIIGKGGQRIKQ 412
           S + M +   G SG + S    +G +  L     TT  ++TIP DL G IIG+ G +I +
Sbjct: 223 SHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINE 282

Query: 413 IRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYLL 451
           IR  SGA IKI  P+EGS DR +TITG+   I  AQYL+
Sbjct: 283 IRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLI 321



 Score = 49.3 bits (116), Expect = 7e-06
 Identities = 24/60 (40%), Positives = 37/60 (61%), Gaps = 1/60 (1%)

Query: 386 PIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKI-DEPLEGSEDRIITITGTQDQI 444
           P +T ++ +P    GS+IGKGG +IK+IR  +GA +++  + L  S +R ITI G    I
Sbjct: 96  PPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSI 155



 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 22/76 (28%), Positives = 41/76 (53%), Gaps = 3/76 (3%)

Query: 140 GSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKP 199
           G +    +RLL+H    G IIG KG  +K++RE +   I + +  CP   +R++ + G  
Sbjct: 9   GLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCP---ERIITLAGPT 65

Query: 200 DRVVECIKIILDLISE 215
           + + +   +I+D + E
Sbjct: 66  NAIFKAFAMIIDKLEE 81



 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 59/215 (27%), Positives = 85/215 (39%), Gaps = 63/215 (29%)

Query: 43  VELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGP---ERILSISADIETIGE 99
           V LR+++ +   G++IGKGG  IK +R    A V V     P   ER ++I+   ++I E
Sbjct: 98  VTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIE 157

Query: 100 ILKKI-----------------IP------------------TLEEGLQLPSPTAT---- 120
            +K+I                 IP                  T++    +P P  T    
Sbjct: 158 CVKQICVVMLETLSQSPPKGVTIPYRPKPSSSPVIFAGGQAYTIQGQYAIPQPDLTKLHQ 217

Query: 121 -----SQLP----------LESDAVECLNYQHYKGSDFDCEL---RLLIHQSLAGGIIGV 162
                S  P          +ES + E   Y  + G D   +     L I   L G IIG 
Sbjct: 218 LAMQQSHFPMTHGNTGFSGIESSSPEVKGY--WAGLDASAQTTSHELTIPNDLIGCIIGR 275

Query: 163 KGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGG 197
           +GAKI E+R+ +   IK+       STDR V I G
Sbjct: 276 QGAKINEIRQMSGAQIKIANP-VEGSTDRQVTITG 309



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 23/58 (39%), Positives = 36/58 (62%), Gaps = 2/58 (3%)

Query: 400 GSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQ 457
           GSIIGK G+ +K++R ESGA I I E      +RIIT+ G  + I  A  ++ + +++
Sbjct: 26  GSIIGKKGESVKKMREESGARINISE--GNCPERIITLAGPTNAIFKAFAMIIDKLEE 81


>gi|148833484 poly(rC) binding protein 2 isoform c [Homo sapiens]
          Length = 331

 Score =  106 bits (265), Expect = 4e-23
 Identities = 59/185 (31%), Positives = 101/185 (54%), Gaps = 22/185 (11%)

Query: 45  LRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKI 104
           +R+L+  K  G++IGK G+++K +R +  A +++ + + PERI++++     I +    I
Sbjct: 16  IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMI 75

Query: 105 IPTLEEGLQ--LPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGV 162
           I  LEE +   + + TA S+ P+                     LRL++  S  G +IG 
Sbjct: 76  IDKLEEDISSSMTNSTAASRPPVT--------------------LRLVVPASQCGSLIGK 115

Query: 163 KGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRVVECIKIILDLISESPIKGRA 222
            G KIKE+RE+T   +++  +  P+ST+R + I G P  ++EC+K I  ++ ESP KG  
Sbjct: 116 GGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVT 175

Query: 223 QPYDP 227
            PY P
Sbjct: 176 IPYRP 180



 Score = 74.7 bits (182), Expect = 2e-13
 Identities = 44/99 (44%), Positives = 58/99 (58%), Gaps = 2/99 (2%)

Query: 355 SEWQMAYEPQGGSGYDYSYAGGRGSYGDLGGPIITT--QVTIPKDLAGSIIGKGGQRIKQ 412
           S + M +   G SG + S    +G +  L     TT  ++TIP DL G IIG+ G +I +
Sbjct: 219 SHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINE 278

Query: 413 IRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYLL 451
           IR  SGA IKI  P+EGS DR +TITG+   I  AQYL+
Sbjct: 279 IRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLI 317



 Score = 49.3 bits (116), Expect = 7e-06
 Identities = 24/60 (40%), Positives = 37/60 (61%), Gaps = 1/60 (1%)

Query: 386 PIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKI-DEPLEGSEDRIITITGTQDQI 444
           P +T ++ +P    GS+IGKGG +IK+IR  +GA +++  + L  S +R ITI G    I
Sbjct: 96  PPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSI 155



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 59/211 (27%), Positives = 85/211 (40%), Gaps = 59/211 (27%)

Query: 43  VELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGP---ERILSISADIETIGE 99
           V LR+++ +   G++IGKGG  IK +R    A V V     P   ER ++I+   ++I E
Sbjct: 98  VTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIE 157

Query: 100 ILKKI-------------IP------------------TLEEGLQLPSPTAT-------- 120
            +K+I             IP                  T++    +P P  T        
Sbjct: 158 CVKQICVVMLESPPKGVTIPYRPKPSSSPVIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQ 217

Query: 121 -SQLP----------LESDAVECLNYQHYKGSDFDCEL---RLLIHQSLAGGIIGVKGAK 166
            S  P          +ES + E   Y  + G D   +     L I   L G IIG +GAK
Sbjct: 218 QSHFPMTHGNTGFSGIESSSPEVKGY--WAGLDASAQTTSHELTIPNDLIGCIIGRQGAK 275

Query: 167 IKELRENTQTTIKLFQECCPHSTDRVVLIGG 197
           I E+R+ +   IK+       STDR V I G
Sbjct: 276 INEIRQMSGAQIKIANP-VEGSTDRQVTITG 305



 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 22/76 (28%), Positives = 41/76 (53%), Gaps = 3/76 (3%)

Query: 140 GSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKP 199
           G +    +RLL+H    G IIG KG  +K++RE +   I + +  CP   +R++ + G  
Sbjct: 9   GLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCP---ERIITLAGPT 65

Query: 200 DRVVECIKIILDLISE 215
           + + +   +I+D + E
Sbjct: 66  NAIFKAFAMIIDKLEE 81



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 23/58 (39%), Positives = 36/58 (62%), Gaps = 2/58 (3%)

Query: 400 GSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQ 457
           GSIIGK G+ +K++R ESGA I I E      +RIIT+ G  + I  A  ++ + +++
Sbjct: 26  GSIIGKKGESVKKMREESGARINISE--GNCPERIITLAGPTNAIFKAFAMIIDKLEE 81


>gi|194306631 poly(rC) binding protein 3 isoform 1 [Homo sapiens]
          Length = 371

 Score =  106 bits (264), Expect = 5e-23
 Identities = 59/185 (31%), Positives = 101/185 (54%), Gaps = 22/185 (11%)

Query: 45  LRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKI 104
           +R+L+  K  G++IGK G+ +K +R +  A +++ + + PERI++I+   + I +    I
Sbjct: 48  IRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPERIVTITGPTDAIFKAFAMI 107

Query: 105 IPTLEEGL--QLPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGV 162
               EE +   + +  ATS+ P+                     LRL++  S  G +IG 
Sbjct: 108 AYKFEEDIINSMSNSPATSKPPVT--------------------LRLVVPASQCGSLIGK 147

Query: 163 KGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRVVECIKIILDLISESPIKGRA 222
            G+KIKE+RE+T   +++  +  P+ST+R V I G PD +++C+K I  ++ ESP KG  
Sbjct: 148 GGSKIKEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLESPPKGAT 207

Query: 223 QPYDP 227
            PY P
Sbjct: 208 IPYRP 212



 Score = 70.9 bits (172), Expect = 2e-12
 Identities = 39/76 (51%), Positives = 47/76 (61%)

Query: 376 GRGSYGDLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRII 435
           G+ S  D   P  T ++TIP DL G IIG+ G +I +IR  SGA IKI    EGS +R I
Sbjct: 282 GQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSERQI 341

Query: 436 TITGTQDQIQNAQYLL 451
           TITGT   I  AQYL+
Sbjct: 342 TITGTPANISLAQYLI 357



 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 25/60 (41%), Positives = 40/60 (66%), Gaps = 1/60 (1%)

Query: 386 PIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKI-DEPLEGSEDRIITITGTQDQI 444
           P +T ++ +P    GS+IGKGG +IK+IR  +GA +++  + L  S +R +TI+GT D I
Sbjct: 128 PPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAI 187



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 25/48 (52%), Positives = 31/48 (64%), Gaps = 2/48 (4%)

Query: 400 GSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNA 447
           GSIIGK G+ +K++R ESGA I I E      +RI+TITG  D I  A
Sbjct: 58  GSIIGKKGETVKKMREESGARINISE--GNCPERIVTITGPTDAIFKA 103



 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 23/70 (32%), Positives = 37/70 (52%), Gaps = 3/70 (4%)

Query: 140 GSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKP 199
           G +    +RLL+H    G IIG KG  +K++RE +   I + +  CP   +R+V I G  
Sbjct: 41  GLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCP---ERIVTITGPT 97

Query: 200 DRVVECIKII 209
           D + +   +I
Sbjct: 98  DAIFKAFAMI 107



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 27/85 (31%), Positives = 43/85 (50%), Gaps = 8/85 (9%)

Query: 43  VELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGP---ERILSISADIETIGE 99
           V LR+++ +   G++IGKGG  IK +R    A V V     P   ER ++IS   + I +
Sbjct: 130 VTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQ 189

Query: 100 ILKKIIPTLEEGLQLPSPTATSQLP 124
            +K+I   +     L SP   + +P
Sbjct: 190 CVKQICVVM-----LESPPKGATIP 209



 Score = 31.2 bits (69), Expect = 2.1
 Identities = 19/54 (35%), Positives = 28/54 (51%), Gaps = 1/54 (1%)

Query: 149 LLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRV 202
           L I   L G IIG +G KI E+R+ +   IK+       S++R + I G P  +
Sbjct: 298 LTIPNDLIGCIIGRQGTKINEIRQMSGAQIKI-ANATEGSSERQITITGTPANI 350


>gi|14670373 poly(rC) binding protein 4 isoform c [Homo sapiens]
          Length = 403

 Score = 99.8 bits (247), Expect = 5e-21
 Identities = 59/185 (31%), Positives = 93/185 (50%), Gaps = 20/185 (10%)

Query: 45  LRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKI 104
           LR+L+  K  G++IGK G+ +K +R   +A +++ + S PERI +I+     +   +  I
Sbjct: 20  LRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSCPERITTITGSTAAVFHAVSMI 79

Query: 105 IPTLEEGL-QLPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGVK 163
              L+E L   P+       P                      LRL+I  S  G +IG  
Sbjct: 80  AFKLDEDLCAAPANGGNVSRP-------------------PVTLRLVIPASQCGSLIGKA 120

Query: 164 GAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRVVECIKIILDLISESPIKGRAQ 223
           G KIKE+RE T   +++  +  P+ST+R V + G PD ++ C++ I  +I ESP KG   
Sbjct: 121 GTKIKEIRETTGAQVQVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVILESPPKGATI 180

Query: 224 PYDPN 228
           PY P+
Sbjct: 181 PYHPS 185



 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 30/70 (42%), Positives = 42/70 (60%)

Query: 382 DLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQ 441
           D G    + +  +P DL G +IG+ G +I +IR  SGA IKI    EG+ +R +TITG+ 
Sbjct: 236 DPGTQTSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAEGAGERHVTITGSP 295

Query: 442 DQIQNAQYLL 451
             I  AQYL+
Sbjct: 296 VSIALAQYLI 305



 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 24/65 (36%), Positives = 41/65 (63%), Gaps = 1/65 (1%)

Query: 381 GDLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKI-DEPLEGSEDRIITITG 439
           G++  P +T ++ IP    GS+IGK G +IK+IR  +GA +++  + L  S +R +T++G
Sbjct: 95  GNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPNSTERAVTVSG 154

Query: 440 TQDQI 444
             D I
Sbjct: 155 VPDAI 159



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 49/195 (25%), Positives = 80/195 (41%), Gaps = 39/195 (20%)

Query: 43  VELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGP---ERILSIS----ADIE 95
           V LR+++ +   G++IGK G  IK +R    A V V     P   ER +++S    A I 
Sbjct: 102 VTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPNSTERAVTVSGVPDAIIL 161

Query: 96  TIGEILKKIIPTLEEGLQLP---------------------------SPTATSQL-PLES 127
            + +I   I+ +  +G  +P                           +P   ++L  L S
Sbjct: 162 CVRQICAVILESPPKGATIPYHPSLSLGTVLLSANQGFSVQGQYGAVTPAEVTKLQQLSS 221

Query: 128 DAVECLNYQHYKGSDFDCEL---RLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQEC 184
            AV         G D   +      L+   L G +IG +G+KI E+R+ +   IK+  + 
Sbjct: 222 HAVPFATPSVVPGLDPGTQTSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQ- 280

Query: 185 CPHSTDRVVLIGGKP 199
              + +R V I G P
Sbjct: 281 AEGAGERHVTITGSP 295



 Score = 38.5 bits (88), Expect = 0.013
 Identities = 22/48 (45%), Positives = 30/48 (62%), Gaps = 2/48 (4%)

Query: 400 GSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNA 447
           GSIIGK G+ +K+IR +S A I I E      +RI TITG+   + +A
Sbjct: 30  GSIIGKKGETVKRIREQSSARITISE--GSCPERITTITGSTAAVFHA 75


>gi|14670369 poly(rC) binding protein 4 isoform c [Homo sapiens]
          Length = 403

 Score = 99.8 bits (247), Expect = 5e-21
 Identities = 59/185 (31%), Positives = 93/185 (50%), Gaps = 20/185 (10%)

Query: 45  LRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKI 104
           LR+L+  K  G++IGK G+ +K +R   +A +++ + S PERI +I+     +   +  I
Sbjct: 20  LRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSCPERITTITGSTAAVFHAVSMI 79

Query: 105 IPTLEEGL-QLPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGVK 163
              L+E L   P+       P                      LRL+I  S  G +IG  
Sbjct: 80  AFKLDEDLCAAPANGGNVSRP-------------------PVTLRLVIPASQCGSLIGKA 120

Query: 164 GAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRVVECIKIILDLISESPIKGRAQ 223
           G KIKE+RE T   +++  +  P+ST+R V + G PD ++ C++ I  +I ESP KG   
Sbjct: 121 GTKIKEIRETTGAQVQVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVILESPPKGATI 180

Query: 224 PYDPN 228
           PY P+
Sbjct: 181 PYHPS 185



 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 30/70 (42%), Positives = 42/70 (60%)

Query: 382 DLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQ 441
           D G    + +  +P DL G +IG+ G +I +IR  SGA IKI    EG+ +R +TITG+ 
Sbjct: 236 DPGTQTSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAEGAGERHVTITGSP 295

Query: 442 DQIQNAQYLL 451
             I  AQYL+
Sbjct: 296 VSIALAQYLI 305



 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 24/65 (36%), Positives = 41/65 (63%), Gaps = 1/65 (1%)

Query: 381 GDLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKI-DEPLEGSEDRIITITG 439
           G++  P +T ++ IP    GS+IGK G +IK+IR  +GA +++  + L  S +R +T++G
Sbjct: 95  GNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPNSTERAVTVSG 154

Query: 440 TQDQI 444
             D I
Sbjct: 155 VPDAI 159



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 49/195 (25%), Positives = 80/195 (41%), Gaps = 39/195 (20%)

Query: 43  VELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGP---ERILSIS----ADIE 95
           V LR+++ +   G++IGK G  IK +R    A V V     P   ER +++S    A I 
Sbjct: 102 VTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPNSTERAVTVSGVPDAIIL 161

Query: 96  TIGEILKKIIPTLEEGLQLP---------------------------SPTATSQL-PLES 127
            + +I   I+ +  +G  +P                           +P   ++L  L S
Sbjct: 162 CVRQICAVILESPPKGATIPYHPSLSLGTVLLSANQGFSVQGQYGAVTPAEVTKLQQLSS 221

Query: 128 DAVECLNYQHYKGSDFDCEL---RLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQEC 184
            AV         G D   +      L+   L G +IG +G+KI E+R+ +   IK+  + 
Sbjct: 222 HAVPFATPSVVPGLDPGTQTSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQ- 280

Query: 185 CPHSTDRVVLIGGKP 199
              + +R V I G P
Sbjct: 281 AEGAGERHVTITGSP 295



 Score = 38.5 bits (88), Expect = 0.013
 Identities = 22/48 (45%), Positives = 30/48 (62%), Gaps = 2/48 (4%)

Query: 400 GSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNA 447
           GSIIGK G+ +K+IR +S A I I E      +RI TITG+   + +A
Sbjct: 30  GSIIGKKGETVKRIREQSSARITISE--GSCPERITTITGSTAAVFHA 75


>gi|194306633 poly(rC) binding protein 3 isoform 2 [Homo sapiens]
          Length = 345

 Score = 93.6 bits (231), Expect = 3e-19
 Identities = 52/174 (29%), Positives = 95/174 (54%), Gaps = 22/174 (12%)

Query: 45  LRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKI 104
           +R+L+  K  G++IGK G+ +K +R +  A +++ + + PERI++I+   + I +    I
Sbjct: 48  IRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPERIVTITGPTDAIFKAFAMI 107

Query: 105 IPTLEEGL--QLPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGV 162
               EE +   + +  ATS+ P+                     LRL++  S  G +IG 
Sbjct: 108 AYKFEEDIINSMSNSPATSKPPVT--------------------LRLVVPASQCGSLIGK 147

Query: 163 KGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRVVECIKIILDLISES 216
            G+KIKE+RE+T   +++  +  P+ST+R V I G PD +++C+K I  ++ E+
Sbjct: 148 GGSKIKEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLEA 201



 Score = 70.9 bits (172), Expect = 2e-12
 Identities = 39/76 (51%), Positives = 47/76 (61%)

Query: 376 GRGSYGDLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRII 435
           G+ S  D   P  T ++TIP DL G IIG+ G +I +IR  SGA IKI    EGS +R I
Sbjct: 256 GQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSERQI 315

Query: 436 TITGTQDQIQNAQYLL 451
           TITGT   I  AQYL+
Sbjct: 316 TITGTPANISLAQYLI 331



 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 25/60 (41%), Positives = 40/60 (66%), Gaps = 1/60 (1%)

Query: 386 PIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKI-DEPLEGSEDRIITITGTQDQI 444
           P +T ++ +P    GS+IGKGG +IK+IR  +GA +++  + L  S +R +TI+GT D I
Sbjct: 128 PPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAI 187



 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 54/198 (27%), Positives = 82/198 (41%), Gaps = 41/198 (20%)

Query: 43  VELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGP---ERILSISADIETIGE 99
           V LR+++ +   G++IGKGG  IK +R    A V V     P   ER ++IS   + I +
Sbjct: 130 VTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQ 189

Query: 100 ILKKIIP------TLEEGLQLPSPTAT------------------------SQLPLESDA 129
            +K+I        T++    +P P  T                         +LPL S +
Sbjct: 190 CVKQICVVMLEAYTIQGQYAIPHPDLTKLHQLAMQQTPFPPLGQTNPAFPGEKLPLHS-S 248

Query: 130 VECLNYQHYKGSDFDCE-----LRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQEC 184
            E  N    + S  D         L I   L G IIG +G KI E+R+ +   IK+    
Sbjct: 249 EEAQNLMG-QSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKI-ANA 306

Query: 185 CPHSTDRVVLIGGKPDRV 202
              S++R + I G P  +
Sbjct: 307 TEGSSERQITITGTPANI 324



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 25/48 (52%), Positives = 31/48 (64%), Gaps = 2/48 (4%)

Query: 400 GSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNA 447
           GSIIGK G+ +K++R ESGA I I E      +RI+TITG  D I  A
Sbjct: 58  GSIIGKKGETVKKMREESGARINISE--GNCPERIVTITGPTDAIFKA 103



 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 23/70 (32%), Positives = 37/70 (52%), Gaps = 3/70 (4%)

Query: 140 GSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKP 199
           G +    +RLL+H    G IIG KG  +K++RE +   I + +  CP   +R+V I G  
Sbjct: 41  GLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCP---ERIVTITGPT 97

Query: 200 DRVVECIKII 209
           D + +   +I
Sbjct: 98  DAIFKAFAMI 107


>gi|56549651 neuro-oncological ventral antigen 1 isoform 2 [Homo
           sapiens]
          Length = 483

 Score = 70.5 bits (171), Expect = 3e-12
 Identities = 57/209 (27%), Positives = 102/209 (48%), Gaps = 20/209 (9%)

Query: 21  KRPAEDMEEEQAFKRSRN-TDEMVELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVP 79
           KRP E   E  + KR+    D    L++L+ S  AG++IGKGG+ I  L+ +  A++ + 
Sbjct: 27  KRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLS 86

Query: 80  DSSG-----PERILSISADIETIGEILKKIIPTLEEGLQLPSPTATSQLPLESDAVECLN 134
            S        ER+  I   +E +  +   I   + E   +P   A      +++ V  L 
Sbjct: 87  KSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKIRE---MPQNVA------KTEPVSILQ 137

Query: 135 YQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCP---HSTDR 191
            Q     D   ++++++  S AG IIG  GA +K + E +   ++L Q+  P   +  +R
Sbjct: 138 PQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQK--PDGINLQER 195

Query: 192 VVLIGGKPDRVVECIKIILDLISESPIKG 220
           VV + G+P++  + +++I+  I E P  G
Sbjct: 196 VVTVSGEPEQNRKAVELIIQKIQEDPQSG 224



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 25/68 (36%), Positives = 44/68 (64%), Gaps = 3/68 (4%)

Query: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKID---EPLEGSEDRIITITGTQDQIQNA 447
           ++ +P++L G+I+GKGG+ + + +  +GA I+I    E + G+ +R +TITGT    Q A
Sbjct: 401 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAA 460

Query: 448 QYLLQNSV 455
           QYL+   +
Sbjct: 461 QYLITQRI 468



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 25/70 (35%), Positives = 42/70 (60%), Gaps = 3/70 (4%)

Query: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLE---GSEDRIITITGTQDQIQNA 447
           +V IP   AGSIIGKGGQ I Q++ E+GA+IK+ +  +   G+ +R+  I GT + +   
Sbjct: 53  KVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAV 112

Query: 448 QYLLQNSVKQ 457
              +   +++
Sbjct: 113 HGFIAEKIRE 122



 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 20/69 (28%), Positives = 43/69 (62%), Gaps = 2/69 (2%)

Query: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEG--SEDRIITITGTQDQIQNAQ 448
           ++ +P   AG IIGKGG  +K +  +SGA +++ +  +G   ++R++T++G  +Q + A 
Sbjct: 151 KIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAV 210

Query: 449 YLLQNSVKQ 457
            L+   +++
Sbjct: 211 ELIIQKIQE 219


>gi|5902724 neuro-oncological ventral antigen 2 [Homo sapiens]
          Length = 492

 Score = 70.5 bits (171), Expect = 3e-12
 Identities = 59/207 (28%), Positives = 96/207 (46%), Gaps = 22/207 (10%)

Query: 21  KRPAEDMEEEQAFKRSRNTDEMVE--LRILLQSKNAGAVIGKGGKNIKALRTDYNASVSV 78
           KRP E   E    KRS NT E  E  L++L+ S  AG++IGKGG+ I  L+ +  A++ +
Sbjct: 10  KRPLETPPEVVCTKRS-NTGEEGEYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKL 68

Query: 79  PDSSG-----PERILSISADIETIGEILKKIIPTLEEGLQLPSPTATSQLPLESDAVECL 133
             S        ER+  +    E +  +   I   + E           Q   + + V  L
Sbjct: 69  SKSKDFYPGTTERVCLVQGTAEALNAVHSFIAEKVRE---------IPQAMTKPEVVNIL 119

Query: 134 NYQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHS---TD 190
             Q     D   + +L++  S AG IIG  GA +K + E +   ++L Q+  P      +
Sbjct: 120 QPQTTMNPDRAKQAKLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQK--PEGINLQE 177

Query: 191 RVVLIGGKPDRVVECIKIILDLISESP 217
           RVV + G+P++V + +  I+  + E P
Sbjct: 178 RVVTVSGEPEQVHKAVSAIVQKVQEDP 204



 Score = 52.8 bits (125), Expect = 7e-07
 Identities = 34/113 (30%), Positives = 54/113 (47%), Gaps = 28/113 (24%)

Query: 371 YSYAGGRGSYGDLGGPIITT-------------------------QVTIPKDLAGSIIGK 405
           Y  AG  G  G  GGP++                           ++ +P++L G+I+GK
Sbjct: 365 YLGAGAGGGAGGGGGPLVAAAAAAGAAGGFLTAEKLAAESAKELVEIAVPENLVGAILGK 424

Query: 406 GGQRIKQIRHESGASIKID---EPLEGSEDRIITITGTQDQIQNAQYLLQNSV 455
           GG+ + + +  +GA I+I    E L G+ +R +TITG+    Q AQYL+   V
Sbjct: 425 GGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAATQAAQYLISQRV 477



 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 25/70 (35%), Positives = 42/70 (60%), Gaps = 3/70 (4%)

Query: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLE---GSEDRIITITGTQDQIQNA 447
           +V IP   AGSIIGKGGQ I Q++ E+GA+IK+ +  +   G+ +R+  + GT + +   
Sbjct: 36  KVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLVQGTAEALNAV 95

Query: 448 QYLLQNSVKQ 457
              +   V++
Sbjct: 96  HSFIAEKVRE 105



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 21/69 (30%), Positives = 42/69 (60%), Gaps = 2/69 (2%)

Query: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEG--SEDRIITITGTQDQIQNAQ 448
           ++ +P   AG IIGKGG  +K +  +SGA +++ +  EG   ++R++T++G  +Q+  A 
Sbjct: 134 KLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPEGINLQERVVTVSGEPEQVHKAV 193

Query: 449 YLLQNSVKQ 457
             +   V++
Sbjct: 194 SAIVQKVQE 202



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 30/105 (28%), Positives = 50/105 (47%), Gaps = 2/105 (1%)

Query: 115 PSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENT 174
           P    + + PLE+        +   G + +  L++LI    AG IIG  G  I +L++ T
Sbjct: 3   PEAPDSRKRPLETPPEVVCTKRSNTGEEGEYFLKVLIPSYAAGSIIGKGGQTIVQLQKET 62

Query: 175 QTTIKL--FQECCPHSTDRVVLIGGKPDRVVECIKIILDLISESP 217
             TIKL   ++  P +T+RV L+ G  + +      I + + E P
Sbjct: 63  GATIKLSKSKDFYPGTTERVCLVQGTAEALNAVHSFIAEKVREIP 107


>gi|154355000 KH-type splicing regulatory protein [Homo sapiens]
          Length = 711

 Score = 70.1 bits (170), Expect = 4e-12
 Identities = 94/423 (22%), Positives = 159/423 (37%), Gaps = 104/423 (24%)

Query: 55  GAVIGKGGKNIKALRTDYNASVSV-PDSSG-PERILSISADIETIGEILKKIIPTLEEGL 112
           G +IG+GG+ I  ++ D    V + PDS G PER +S++   E++ +    +   +  G 
Sbjct: 157 GLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGR 216

Query: 113 QLPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRE 172
             P                   + +  G        ++I    AG +IG  G  IK+L+E
Sbjct: 217 GGPPGQF---------------HDNANGGQNGTVQEIMIPAGKAGLVIGKGGETIKQLQE 261

Query: 173 NTQTTIKLFQECCPHST-DRVVLIGGKPDRVVECIKIILDLISESPIKGRAQPYDPNFYD 231
                + L Q+   ++  D+ + I G P +V +  ++++D++ E                
Sbjct: 262 RAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACEMVMDILRER--------------- 306

Query: 232 ETYDYGGFTMMFDDRRGRPVGFPMRGRGGFDRMPP--------GRGGRPMPPSRRDYDDM 283
              D GGF        G    +  R  GG D   P        GR G  +   + D    
Sbjct: 307 ---DQGGF--------GDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKKIQND---- 351

Query: 284 SPRRGPPPPPPGRGGRGGSRARNLPLPPPPPPRGG----DLMAYDRRGRPGDRYDGMVGF 339
               G         G G  +  ++  PP           DL+   R G PG         
Sbjct: 352 ---AGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPG--------- 399

Query: 340 SADETWDSAIDTWSPSEWQMAYEPQGGSGYDYSYAG---GRGSYGDLGGPIITTQVTIPK 396
                                  P GG G      G   G+G++G  GG +     +IP 
Sbjct: 400 -----------------------PPGGPGMPPGGRGRGRGQGNWGPPGGEMT---FSIPT 433

Query: 397 DLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSED---RIITITGTQDQIQNAQYLLQN 453
              G +IG+GG+ +K I  ++GA ++I   L  + D   ++  I G+  QI +A+ L++ 
Sbjct: 434 HKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEE 493

Query: 454 SVK 456
            ++
Sbjct: 494 KIE 496



 Score = 66.6 bits (161), Expect = 4e-11
 Identities = 56/217 (25%), Positives = 85/217 (39%), Gaps = 43/217 (19%)

Query: 279 DYDDMSPRRGPPPPPPGRGGRGGSRARNLPLPPPPPPRGGDL------------------ 320
           DY    P  GPPPP  G GG GG+       PPP PP  GD                   
Sbjct: 3   DYSTGGPPPGPPPPAGGGGGAGGAGGG----PPPGPPGAGDRGGGGPGGGGPGGGSAGGP 58

Query: 321 MAYDRRGRPGDRYDGM-------------VGFSADETWDSAIDTWSPSEWQMAYEPQGGS 367
                 G PG R D               +G  A  T +++   +     +   E  G  
Sbjct: 59  SQPPGGGGPGIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLE-DGDQ 117

Query: 368 GYDYSYAGGRGSYGDLGGPI-------ITTQVTIPKDLAGSIIGKGGQRIKQIRHESGAS 420
                 A    S     GPI       +T +  +P  + G IIG+GG++I +I+ +SG  
Sbjct: 118 PESKKLASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCK 177

Query: 421 IKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQ 457
           ++I     G  +R +++TG  + +Q A+ +L + V +
Sbjct: 178 VQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSR 214



 Score = 37.4 bits (85), Expect = 0.029
 Identities = 22/76 (28%), Positives = 42/76 (55%), Gaps = 3/76 (3%)

Query: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKI--DEPLEGSEDRIITITGTQDQIQNAQ 448
           ++ IP   AG +IGKGG+ IKQ++  +G  + +  D     + D+ + I G   ++Q A 
Sbjct: 237 EIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQAC 296

Query: 449 YLLQNSVKQYADVEGF 464
            ++ + +++  D  GF
Sbjct: 297 EMVMDILRE-RDQGGF 311



 Score = 29.6 bits (65), Expect = 6.1
 Identities = 12/35 (34%), Positives = 20/35 (57%)

Query: 44  ELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSV 78
           E+   + +   G VIG+GG+N+KA+     A V +
Sbjct: 426 EMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEI 460


>gi|17402900 far upstream element-binding protein [Homo sapiens]
          Length = 644

 Score = 66.6 bits (161), Expect = 4e-11
 Identities = 105/472 (22%), Positives = 169/472 (35%), Gaps = 125/472 (26%)

Query: 21  KRPAEDMEEEQAFKRSRNTDEM-VELRILLQSKN--------------AGAVIGKGGKNI 65
           KRP ED ++  A K +   D    +L  + Q ++               G +IG+GG+ I
Sbjct: 64  KRPLEDGDQPDAKKVAPQNDSFGTQLPPMHQQQSRSVMTEEYKVPDGMVGFIIGRGGEQI 123

Query: 66  KALRTDYNASVSV-PDSSG-PERILSISADIETIGEILKKIIPTLEEGLQLPSPTATSQL 123
             ++ +    + + PDS G PER   ++   E++    + +   +E+G   P        
Sbjct: 124 SRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSAKRLLDQIVEKGRPAPG------- 176

Query: 124 PLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQE 183
                        H+     +    ++I  S AG +IG  G  IK+L+E     + + Q+
Sbjct: 177 ------------FHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQD 224

Query: 184 CCPHST--DRVVLIGGKPDRVVECIKIILDLISESPIKGRAQPYDPNFYDETYDYGGFTM 241
             P +T  D+ + I G P +V +  +++L+LI                     D GGF  
Sbjct: 225 -GPQNTGADKPLRITGDPYKVQQAKEMVLELIR--------------------DQGGFRE 263

Query: 242 MFDDRRGRPVGFPMRGRGGFDRMPP--------GRGGRPMPPSRRDYD---DMSPRRGPP 290
           + ++      G  + G  G D   P        GR G  +   + D        P  G  
Sbjct: 264 VRNE-----YGSRIGGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTT 318

Query: 291 PPPPGRGGRGGSRARNLPLPPPPPPRGG----DLMAYDRRGRPGDRYDGMVGFSADETWD 346
           P           R   +  PP           DL+   + G PG    G  G    +   
Sbjct: 319 P----------ERIAQITGPPDRCQHAAEIITDLLRSVQAGNPGGPGPGGRGRGRGQ--- 365

Query: 347 SAIDTWSPSEWQMAYEPQGGSGYDYSYAGGRGSYGDLGGPIITTQVTIPKDLAGSIIGKG 406
                     W M   P GG                    +      +P    G IIGKG
Sbjct: 366 --------GNWNMG--PPGG--------------------LQEFNFIVPTGKTGLIIGKG 395

Query: 407 GQRIKQIRHESGASIKIDE---PLEGSEDRIITITGTQDQIQNAQYLLQNSV 455
           G+ IK I  +SGA I++     P      ++ TI GT  QI  A+ L++  +
Sbjct: 396 GETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKI 447



 Score = 56.2 bits (134), Expect = 6e-08
 Identities = 27/78 (34%), Positives = 46/78 (58%)

Query: 387 IITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQN 446
           ++T +  +P  + G IIG+GG++I +I+ ESG  I+I     G  +R   +TGT + +Q+
Sbjct: 100 VMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQS 159

Query: 447 AQYLLQNSVKQYADVEGF 464
           A+ LL   V++     GF
Sbjct: 160 AKRLLDQIVEKGRPAPGF 177



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 24/80 (30%), Positives = 43/80 (53%)

Query: 377 RGSYGDLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIIT 436
           R  YG   G      V IP+   G +IG+ G+ IK+I++++G  I+       + +RI  
Sbjct: 265 RNEYGSRIGGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPERIAQ 324

Query: 437 ITGTQDQIQNAQYLLQNSVK 456
           ITG  D+ Q+A  ++ + ++
Sbjct: 325 ITGPPDRCQHAAEIITDLLR 344



 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 24/79 (30%), Positives = 44/79 (55%), Gaps = 3/79 (3%)

Query: 380 YGDLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKI--DEPLEGSEDRIITI 437
           +GD  G  +  ++ IP   AG +IGKGG+ IKQ++  +G  + +  D P     D+ + I
Sbjct: 179 HGDGPGNAVQ-EIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRI 237

Query: 438 TGTQDQIQNAQYLLQNSVK 456
           TG   ++Q A+ ++   ++
Sbjct: 238 TGDPYKVQQAKEMVLELIR 256



 Score = 36.2 bits (82), Expect = 0.065
 Identities = 63/274 (22%), Positives = 98/274 (35%), Gaps = 42/274 (15%)

Query: 55  GAVIGKGGKNIKALRTDYNASVSVPDSSG--PERILSISAD---IETIGEILKKIIPTLE 109
           G VIG+ G+ IK ++ D    +      G  PERI  I+      +   EI+  ++ +++
Sbjct: 288 GIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPERIAQITGPPDRCQHAAEIITDLLRSVQ 347

Query: 110 EGLQL-PSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIK 168
            G    P P    +   + +     N     G     E   ++     G IIG  G  IK
Sbjct: 348 AGNPGGPGPGGRGRGRGQGN----WNMGPPGGLQ---EFNFIVPTGKTGLIIGKGGETIK 400

Query: 169 ELRENTQTTIKLFQECCPHSTDRVVL--IGGKPDRVVECIKIILDLISESPIKGRAQPYD 226
            + + +   I+L +   P++   + L  I G P ++    ++I     E  I G   P  
Sbjct: 401 SISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLI-----EEKIGGPVNPLG 455

Query: 227 PNFYDETYDYGGFTMMFDDRRGRPVGFPMRGRGGFDRMPPGRGGRPMPPSRRDYDDMSPR 286
           P      +   G           P G P          PPG G    P +   Y+   P 
Sbjct: 456 PPVPHGPHGVPG-----------PHGPPG---------PPGPGTPMGPYNPAPYNPGPPG 495

Query: 287 RGP--PPPPPGRGGRGGSRARNLPLPPPPPPRGG 318
             P  PP P    G G +        PP P + G
Sbjct: 496 PAPHGPPAPYAPQGWGNAYPHWQQQAPPDPAKAG 529


>gi|56549653 neuro-oncological ventral antigen 1 isoform 1 [Homo
           sapiens]
          Length = 507

 Score = 63.5 bits (153), Expect = 4e-10
 Identities = 60/235 (25%), Positives = 102/235 (43%), Gaps = 48/235 (20%)

Query: 21  KRPAEDMEEEQAFKRSRN-TDEMVELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVP 79
           KRP E   E  + KR+    D    L++L+ S  AG++IGKGG+ I  L+ +  A++ + 
Sbjct: 27  KRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLS 86

Query: 80  DSSG-----PERILSISADIETIGEILKKIIPTLEEGLQ--------------------- 113
            S        ER+  I   +E +  +   I   + E  Q                     
Sbjct: 87  KSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDR 146

Query: 114 ----LP-SPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIK 168
               LP SPT T   P +       N           ++++++  S AG IIG  GA +K
Sbjct: 147 IKQTLPSSPTTTKSSPSDPMTTSRAN-----------QVKIIVPNSTAGLIIGKGGATVK 195

Query: 169 ELRENTQTTIKLFQECCP---HSTDRVVLIGGKPDRVVECIKIILDLISESPIKG 220
            + E +   ++L Q+  P   +  +RVV + G+P++  + +++I+  I E P  G
Sbjct: 196 AVMEQSGAWVQLSQK--PDGINLQERVVTVSGEPEQNRKAVELIIQKIQEDPQSG 248



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 25/68 (36%), Positives = 44/68 (64%), Gaps = 3/68 (4%)

Query: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKID---EPLEGSEDRIITITGTQDQIQNA 447
           ++ +P++L G+I+GKGG+ + + +  +GA I+I    E + G+ +R +TITGT    Q A
Sbjct: 425 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAA 484

Query: 448 QYLLQNSV 455
           QYL+   +
Sbjct: 485 QYLITQRI 492



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 25/70 (35%), Positives = 42/70 (60%), Gaps = 3/70 (4%)

Query: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLE---GSEDRIITITGTQDQIQNA 447
           +V IP   AGSIIGKGGQ I Q++ E+GA+IK+ +  +   G+ +R+  I GT + +   
Sbjct: 53  KVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAV 112

Query: 448 QYLLQNSVKQ 457
              +   +++
Sbjct: 113 HGFIAEKIRE 122



 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 20/69 (28%), Positives = 43/69 (62%), Gaps = 2/69 (2%)

Query: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEG--SEDRIITITGTQDQIQNAQ 448
           ++ +P   AG IIGKGG  +K +  +SGA +++ +  +G   ++R++T++G  +Q + A 
Sbjct: 175 KIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAV 234

Query: 449 YLLQNSVKQ 457
            L+   +++
Sbjct: 235 ELIIQKIQE 243


>gi|100816392 far upstream element (FUSE) binding protein 3 [Homo
           sapiens]
          Length = 572

 Score = 63.2 bits (152), Expect = 5e-10
 Identities = 108/451 (23%), Positives = 166/451 (36%), Gaps = 98/451 (21%)

Query: 21  KRPAEDMEEEQAFKRSRNTDEMVELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVP- 79
           KRP +D    Q          + E    +  K  G +IG+GG+ I  ++ +    + +  
Sbjct: 57  KRPLDDGVGNQLGALVHQRTVITE-EFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIAS 115

Query: 80  DSSG-PERILSISADIETIGE---ILKKIIPTLEEGLQLPSPTATSQLPLESDAVECLNY 135
           +SSG PER   ++   E+I +   +L +I+     G     P   + +   S   E    
Sbjct: 116 ESSGIPERPCVLTGTPESIEQAKRLLGQIVDRCRNG-----PGFHNDIDSNSTIQE---- 166

Query: 136 QHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQEC-CPHSTDRVVL 194
                        +LI  S  G +IG  G  IK+L+E T   + + Q+   P   D+ + 
Sbjct: 167 -------------ILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPLPTGADKPLR 213

Query: 195 IGGKPDRVVECIKIILDLISESPIKGRAQPYDPNFYDETYDYGGFTMMFDDRRGR---PV 251
           I G   +V +  +++L++I E                +  D+ G    F+ R G     V
Sbjct: 214 ITGDAFKVQQAREMVLEIIREK---------------DQADFRGVRGDFNSRMGGGSIEV 258

Query: 252 GFPMRGRGGFDRMPPGRGGRPMPPSRRDYDDMSPRRGPPPPPPGRGGRGGSRARNLPLPP 311
             P    G    +  GR G  +   + D                     G R +  P   
Sbjct: 259 SVPRFAVG----IVIGRNGEMIKKIQND--------------------AGVRIQFKPDDG 294

Query: 312 PPPPRGGDLMAYDRRGRPGDRYDGMVGFSADETWDSAIDTWSPSEWQMAYEPQGGSGYDY 371
             P R   +M       P DR        A       I T        A E  G  G   
Sbjct: 295 ISPERAAQVMG------PPDRCQ-----HAAHIISELILT--------AQERDGFGGLAA 335

Query: 372 SYAGGRG----SYGDLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPL 427
           +   GRG    S G  GG +     T+P D  G +IGKGG+ IK I  +SGA +++    
Sbjct: 336 ARGRGRGRGDWSVGAPGG-VQEITYTVPADKCGLVIGKGGENIKSINQQSGAHVELQRNP 394

Query: 428 EGSED---RIITITGTQDQIQNAQYLLQNSV 455
             + D   R  TI G   QI+ A+ L+   V
Sbjct: 395 PPNSDPNLRRFTIRGVPQQIEVARQLIDEKV 425



 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 28/78 (35%), Positives = 45/78 (57%)

Query: 387 IITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQN 446
           +IT +  +P  + G IIG+GG++I +I+ ESG  I+I     G  +R   +TGT + I+ 
Sbjct: 77  VITEEFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIEQ 136

Query: 447 AQYLLQNSVKQYADVEGF 464
           A+ LL   V +  +  GF
Sbjct: 137 AKRLLGQIVDRCRNGPGF 154



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 27/92 (29%), Positives = 47/92 (51%), Gaps = 4/92 (4%)

Query: 376 GRGSYGDLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKI--DEPLEGSEDR 433
           G G + D+       ++ IP    G +IG+GG+ IKQ++  +G  + +  D PL    D+
Sbjct: 151 GPGFHNDIDSNSTIQEILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPLPTGADK 210

Query: 434 IITITGTQDQIQNAQYLLQNSV--KQYADVEG 463
            + ITG   ++Q A+ ++   +  K  AD  G
Sbjct: 211 PLRITGDAFKVQQAREMVLEIIREKDQADFRG 242



 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 27/94 (28%), Positives = 55/94 (58%), Gaps = 5/94 (5%)

Query: 373 YAGGRGSYGD-LGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEG-S 430
           + G RG +   +GG  I  +V++P+   G +IG+ G+ IK+I++++G  I+  +P +G S
Sbjct: 240 FRGVRGDFNSRMGGGSI--EVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQF-KPDDGIS 296

Query: 431 EDRIITITGTQDQIQNAQYLLQNSVKQYADVEGF 464
            +R   + G  D+ Q+A +++   +    + +GF
Sbjct: 297 PERAAQVMGPPDRCQHAAHIISELILTAQERDGF 330



 Score = 35.4 bits (80), Expect = 0.11
 Identities = 27/86 (31%), Positives = 42/86 (48%), Gaps = 6/86 (6%)

Query: 44  ELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSV----PDSSGPE-RILSISADIETIG 98
           E+   + +   G VIGKGG+NIK++     A V +    P +S P  R  +I    + I 
Sbjct: 356 EITYTVPADKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNSDPNLRRFTIRGVPQQI- 414

Query: 99  EILKKIIPTLEEGLQLPSPTATSQLP 124
           E+ +++I     G  L +P A  Q P
Sbjct: 415 EVARQLIDEKVGGTNLGAPGAFGQSP 440


>gi|238624257 insulin-like growth factor 2 mRNA binding protein 1
           isoform 2 [Homo sapiens]
          Length = 438

 Score = 58.9 bits (141), Expect = 9e-09
 Identities = 52/194 (26%), Positives = 85/194 (43%), Gaps = 28/194 (14%)

Query: 34  KRSRNTDEMVELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSS-----GPERIL 88
           +++R  DE V L+IL  +   G +IGK G+N+K +  D    +++          PER +
Sbjct: 130 EQTRQADE-VPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTI 188

Query: 89  SISADIETI----GEILKKIIPTLEE-------------GLQLPS----PTATSQLPLES 127
           ++   IE       EI+KK+    E              GL L +    P ++S +P   
Sbjct: 189 TVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPP 248

Query: 128 DAVE-CLNYQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCP 186
            +V     Y  +  +     +++ I     G IIG KG  IK+L      +IK+     P
Sbjct: 249 SSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETP 308

Query: 187 HSTDRVVLIGGKPD 200
            S  R+V+I G P+
Sbjct: 309 DSKVRMVIITGPPE 322



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 28/68 (41%), Positives = 38/68 (55%), Gaps = 1/68 (1%)

Query: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEP-LEGSEDRIITITGTQDQIQNAQY 449
           QV IP    G+IIGK GQ IKQ+   + ASIKI  P    S+ R++ ITG  +    AQ 
Sbjct: 270 QVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQG 329

Query: 450 LLQNSVKQ 457
            +   +K+
Sbjct: 330 RIYGKLKE 337



 Score = 35.4 bits (80), Expect = 0.11
 Identities = 18/72 (25%), Positives = 40/72 (55%), Gaps = 2/72 (2%)

Query: 388 ITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKI--DEPLEGSEDRIITITGTQDQIQ 445
           + T + +P   AG +IGKGG+ + ++++ + A + +  D+  + ++  I+ I G     Q
Sbjct: 349 LETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPDENDQVIVKIIGHFYASQ 408

Query: 446 NAQYLLQNSVKQ 457
            AQ  +++ + Q
Sbjct: 409 MAQRKIRDILAQ 420



 Score = 32.3 bits (72), Expect = 0.94
 Identities = 17/43 (39%), Positives = 23/43 (53%)

Query: 43  VELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPE 85
           +E  I + +  AG VIGKGGK +  L+    A V VP    P+
Sbjct: 349 LETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPD 391


>gi|9966803 poly(rC) binding protein 4 isoform a [Homo sapiens]
          Length = 424

 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 30/70 (42%), Positives = 42/70 (60%)

Query: 382 DLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQ 441
           D G    + +  +P DL G +IG+ G +I +IR  SGA IKI    EG+ +R +TITG+ 
Sbjct: 257 DPGTQTSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAEGAGERHVTITGSP 316

Query: 442 DQIQNAQYLL 451
             I  AQYL+
Sbjct: 317 VSIALAQYLI 326



 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 20/57 (35%), Positives = 34/57 (59%)

Query: 172 ENTQTTIKLFQECCPHSTDRVVLIGGKPDRVVECIKIILDLISESPIKGRAQPYDPN 228
           + T   +++  +  P+ST+R V + G PD ++ C++ I  +I ESP KG   PY P+
Sbjct: 150 QTTGAQVQVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVILESPPKGATIPYHPS 206



 Score = 37.0 bits (84), Expect = 0.038
 Identities = 16/38 (42%), Positives = 24/38 (63%)

Query: 381 GDLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESG 418
           G++  P +T ++ IP    GS+IGK G +IK+IR   G
Sbjct: 61  GNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIREVRG 98



 Score = 34.3 bits (77), Expect = 0.25
 Identities = 28/101 (27%), Positives = 42/101 (41%), Gaps = 20/101 (19%)

Query: 73  NASVSVPDSSGPERILSISADIETIGEILKKIIPTLEEGL-QLPSPTATSQLPLESDAVE 131
           +A +++ + S PERI +I+     +   +  I   L+E L   P+       P       
Sbjct: 14  SARITISEGSCPERITTITGSTAAVFHAVSMIAFKLDEDLCAAPANGGNVSRP------- 66

Query: 132 CLNYQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRE 172
                          LRL+I  S  G +IG  G KIKE+RE
Sbjct: 67  ------------PVTLRLVIPASQCGSLIGKAGTKIKEIRE 95


>gi|56237027 insulin-like growth factor 2 mRNA binding protein 1
           isoform 1 [Homo sapiens]
          Length = 577

 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 52/194 (26%), Positives = 84/194 (43%), Gaps = 28/194 (14%)

Query: 34  KRSRNTDEMVELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSS-----GPERIL 88
           K ++  DE V L+IL  +   G +IGK G+N+K +  D    +++          PER +
Sbjct: 269 KDTKTADE-VPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTI 327

Query: 89  SISADIETI----GEILKKIIPTLEE-------------GLQLPS----PTATSQLPLES 127
           ++   IE       EI+KK+    E              GL L +    P ++S +P   
Sbjct: 328 TVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPP 387

Query: 128 DAVE-CLNYQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCP 186
            +V     Y  +  +     +++ I     G IIG KG  IK+L      +IK+     P
Sbjct: 388 SSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETP 447

Query: 187 HSTDRVVLIGGKPD 200
            S  R+V+I G P+
Sbjct: 448 DSKVRMVIITGPPE 461



 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 40/212 (18%), Positives = 86/212 (40%), Gaps = 30/212 (14%)

Query: 11  PNTETNGEFGKRPAEDMEEEQAFKRSRNTDEM-VELRILLQSKNAGAVIGKGGKNIKALR 69
           P     G FG R         A        ++ + LR+L+ ++  GA+IGK G  I+ + 
Sbjct: 163 PENGRRGGFGSRGQPRQGSPVAAGAPAKQQQVDIPLRLLVPTQYVGAIIGKEGATIRNIT 222

Query: 70  TDYNASVSV---PDSSGPERILSISADIETIGEILKKIIPTLEEGLQLPSPTATSQLPLE 126
               + + V    ++   E+ +S+ +  E      K I+  + +  +        ++P  
Sbjct: 223 KQTQSKIDVHRKENAGAAEKAISVHSTPEGCSSACKMILEIMHK--EAKDTKTADEVP-- 278

Query: 127 SDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQT--TIKLFQEC 184
                               L++L H +  G +IG +G  +K++ ++T+T  TI   Q+ 
Sbjct: 279 --------------------LKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDL 318

Query: 185 CPHSTDRVVLIGGKPDRVVECIKIILDLISES 216
             ++ +R + + G  +      + I+  + E+
Sbjct: 319 TLYNPERTITVKGAIENCCRAEQEIMKKVREA 350



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 28/68 (41%), Positives = 38/68 (55%), Gaps = 1/68 (1%)

Query: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEP-LEGSEDRIITITGTQDQIQNAQY 449
           QV IP    G+IIGK GQ IKQ+   + ASIKI  P    S+ R++ ITG  +    AQ 
Sbjct: 409 QVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQG 468

Query: 450 LLQNSVKQ 457
            +   +K+
Sbjct: 469 RIYGKLKE 476



 Score = 35.4 bits (80), Expect = 0.11
 Identities = 18/72 (25%), Positives = 40/72 (55%), Gaps = 2/72 (2%)

Query: 388 ITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKI--DEPLEGSEDRIITITGTQDQIQ 445
           + T + +P   AG +IGKGG+ + ++++ + A + +  D+  + ++  I+ I G     Q
Sbjct: 488 LETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPDENDQVIVKIIGHFYASQ 547

Query: 446 NAQYLLQNSVKQ 457
            AQ  +++ + Q
Sbjct: 548 MAQRKIRDILAQ 559



 Score = 32.3 bits (72), Expect = 0.94
 Identities = 17/43 (39%), Positives = 23/43 (53%)

Query: 43  VELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPE 85
           +E  I + +  AG VIGKGGK +  L+    A V VP    P+
Sbjct: 488 LETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPD 530



 Score = 30.8 bits (68), Expect = 2.7
 Identities = 29/106 (27%), Positives = 49/106 (46%), Gaps = 10/106 (9%)

Query: 351 TWSPSEWQMAYEPQGGSGYDYSYAGG--RGSYGDLGGPIITTQVTIPKDL------AGSI 402
           ++ P E Q+A  P+ G    +   G   +GS    G P    QV IP  L       G+I
Sbjct: 152 SYIPDE-QIAQGPENGRRGGFGSRGQPRQGSPVAAGAPAKQQQVDIPLRLLVPTQYVGAI 210

Query: 403 IGKGGQRIKQIRHESGASIKID-EPLEGSEDRIITITGTQDQIQNA 447
           IGK G  I+ I  ++ + I +  +   G+ ++ I++  T +   +A
Sbjct: 211 IGKEGATIRNITKQTQSKIDVHRKENAGAAEKAISVHSTPEGCSSA 256


>gi|30795212 insulin-like growth factor 2 mRNA binding protein 3
           [Homo sapiens]
          Length = 579

 Score = 56.2 bits (134), Expect = 6e-08
 Identities = 49/188 (26%), Positives = 83/188 (44%), Gaps = 29/188 (15%)

Query: 41  EMVELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSS-----GPERILSISADIE 95
           E + L+IL  +   G +IGK G+N+K +  D +  +++          PER +++  ++E
Sbjct: 275 EEIPLKILAHNNFVGRLIGKEGRNLKKIEQDTDTKITISPLQELTLYNPERTITVKGNVE 334

Query: 96  TIG----EILKKIIPTLEE-------------GLQLPS----PTATSQLPLESDAVECLN 134
           T      EI+KKI  + E              GL L +    P  +   P  S     + 
Sbjct: 335 TCAKAEEEIMKKIRESYENDIASMNLQAHLIPGLNLNALGLFPPTSGMPPPTSGPPSAMT 394

Query: 135 --YQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRV 192
             Y  ++ S+ +  + L I     G IIG +G  IK+L      +IK+     P +  R+
Sbjct: 395 PPYPQFEQSETET-VHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRM 453

Query: 193 VLIGGKPD 200
           V+I G P+
Sbjct: 454 VIITGPPE 461



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 39/177 (22%), Positives = 78/177 (44%), Gaps = 29/177 (16%)

Query: 45  LRILLQSKNAGAVIGKGGKNIKALRTDYNASVSV---PDSSGPERILSISADIETIGEIL 101
           LR+L+ ++  GA+IGK G  I+ +     + + V    ++   E+ ++I +  E      
Sbjct: 198 LRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKSITILSTPEGTSAAC 257

Query: 102 KKIIPTLEEGLQLPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIG 161
           K I+  + +  Q      T ++P                      L++L H +  G +IG
Sbjct: 258 KSILEIMHKEAQ--DIKFTEEIP----------------------LKILAHNNFVGRLIG 293

Query: 162 VKGAKIKELRENTQT--TIKLFQECCPHSTDRVVLIGGKPDRVVECIKIILDLISES 216
            +G  +K++ ++T T  TI   QE   ++ +R + + G  +   +  + I+  I ES
Sbjct: 294 KEGRNLKKIEQDTDTKITISPLQELTLYNPERTITVKGNVETCAKAEEEIMKKIRES 350



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 28/71 (39%), Positives = 40/71 (56%), Gaps = 3/71 (4%)

Query: 389 TTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEG--SEDRIITITGTQDQIQN 446
           T  + IP    G+IIGK GQ IKQ+   +GASIKI  P E   ++ R++ ITG  +    
Sbjct: 407 TVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKI-APAEAPDAKVRMVIITGPPEAQFK 465

Query: 447 AQYLLQNSVKQ 457
           AQ  +   +K+
Sbjct: 466 AQGRIYGKIKE 476



 Score = 37.4 bits (85), Expect = 0.029
 Identities = 20/70 (28%), Positives = 37/70 (52%)

Query: 144 DCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRVV 203
           D  LRLL+     G IIG +GA I+ + + TQ+ I + ++    + ++ + I   P+   
Sbjct: 195 DLPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKSITILSTPEGTS 254

Query: 204 ECIKIILDLI 213
              K IL+++
Sbjct: 255 AACKSILEIM 264



 Score = 37.0 bits (84), Expect = 0.038
 Identities = 19/72 (26%), Positives = 39/72 (54%), Gaps = 2/72 (2%)

Query: 388 ITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKI--DEPLEGSEDRIITITGTQDQIQ 445
           +   + +P   AG +IGKGG+ + ++++ S A + +  D+  + ++  ++ ITG     Q
Sbjct: 488 LEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQTPDENDQVVVKITGHFYACQ 547

Query: 446 NAQYLLQNSVKQ 457
            AQ  +Q  + Q
Sbjct: 548 VAQRKIQEILTQ 559



 Score = 33.5 bits (75), Expect = 0.42
 Identities = 18/43 (41%), Positives = 24/43 (55%)

Query: 43  VELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPE 85
           +E  I + S  AG VIGKGGK +  L+   +A V VP    P+
Sbjct: 488 LEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQTPD 530



 Score = 31.6 bits (70), Expect = 1.6
 Identities = 25/106 (23%), Positives = 51/106 (48%), Gaps = 5/106 (4%)

Query: 362 EPQGGSGYDYSYAGGRGSYGDLGGPI---ITTQVTIPKDLAGSIIGKGGQRIKQIRHESG 418
           +P+G  G     +  +GS G +       +  ++ +P    G+IIGK G  I+ I  ++ 
Sbjct: 167 QPRGRRGLGQRGSSRQGSPGSVSKQKPCDLPLRLLVPTQFVGAIIGKEGATIRNITKQTQ 226

Query: 419 ASIKID-EPLEGSEDRIITITGTQDQIQNA-QYLLQNSVKQYADVE 462
           + I +  +   G+ ++ ITI  T +    A + +L+   K+  D++
Sbjct: 227 SKIDVHRKENAGAAEKSITILSTPEGTSAACKSILEIMHKEAQDIK 272


>gi|5730027 KH domain containing, RNA binding, signal transduction
           associated 1 [Homo sapiens]
          Length = 443

 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 45/134 (33%), Positives = 55/134 (41%), Gaps = 18/134 (13%)

Query: 247 RGRPVGFPMRGRGGFDRMPPGRGGRPMPPSRRDYDDMSPRRGP----------PPPPPGR 296
           RGR  G P+RGRG     PP   GR + P R      +P RG            PPPP  
Sbjct: 282 RGR--GVPVRGRGAAPPPPPVPRGRGVGPPRGALVRGTPVRGAITRGATVTRGVPPPPTV 339

Query: 297 GGRGGSRAR-----NLPLPPPPPPRGGDLMAYDRRGRPGDRYDGMVGFSADETWDSAIDT 351
            G    RAR      +PLPPPP P   +   YD        Y+G  G+ +    DS    
Sbjct: 340 RGAPAPRARTAGIQRIPLPPPPAPETYEEYGYDDT-YAEQSYEGYEGYYSQSQGDSEYYD 398

Query: 352 WSPSEWQMAYEPQG 365
           +   E Q +YE  G
Sbjct: 399 YGHGEVQDSYEAYG 412



 Score = 37.4 bits (85), Expect = 0.029
 Identities = 22/50 (44%), Positives = 23/50 (46%), Gaps = 2/50 (4%)

Query: 267 GRGGRPMPPSRRDYDDMSPRRGPPPPPPGRGGRGGSR--ARNLPLPPPPP 314
           GR G   P         +P R PP P   RGG GGSR  AR  P   PPP
Sbjct: 16  GRSGSMDPSGAHPSVRQTPSRQPPLPHRSRGGGGGSRGGARASPATQPPP 65


>gi|56118219 insulin-like growth factor 2 mRNA binding protein 2
           isoform b [Homo sapiens]
          Length = 556

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 43/169 (25%), Positives = 74/169 (43%), Gaps = 10/169 (5%)

Query: 41  EMVELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSS-----GPERILSISADIE 95
           E + L+IL  +   G +IGK G+N+K +  +    +++          PER +++   +E
Sbjct: 273 EEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITVKGTVE 332

Query: 96  TIG----EILKKIIPTLEEGLQLPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLI 151
                  EI+KK+    E  + L   T +          +   + H+        + L I
Sbjct: 333 ACASAEIEIMKKLREAFENDM-LAVNTHSGYFSSLYPHHQFGPFPHHHSYPEQEIVNLFI 391

Query: 152 HQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPD 200
                G IIG KGA IK+L      +IK+     P  ++R+V+I G P+
Sbjct: 392 PTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPE 440



 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 38/158 (24%), Positives = 70/158 (44%), Gaps = 29/158 (18%)

Query: 45  LRILLQSKNAGAVIGKGGKNIKALRTDYNASVSV---PDSSGPERILSISADIETIGEIL 101
           LRIL+ ++  GA+IGK G  IK +     + V +    +S   E+ ++I A  E   E  
Sbjct: 196 LRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTSEAC 255

Query: 102 KKIIPTLEEGLQLPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIG 161
           + I+  +++               E+D  +            +  L++L H  L G +IG
Sbjct: 256 RMILEIMQK---------------EADETKLAE---------EIPLKILAHNGLVGRLIG 291

Query: 162 VKGAKIKELRENTQT--TIKLFQECCPHSTDRVVLIGG 197
            +G  +K++   T T  TI   Q+   ++ +R + + G
Sbjct: 292 KEGRNLKKIEHETGTKITISSLQDLSIYNPERTITVKG 329



 Score = 42.7 bits (99), Expect = 7e-04
 Identities = 27/66 (40%), Positives = 38/66 (57%), Gaps = 3/66 (4%)

Query: 394 IPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSE--DRIITITGTQDQIQNAQYLL 451
           IP    G+IIGK G  IKQ+   +GASIKI  P EG +  +R++ ITG  +    AQ  +
Sbjct: 391 IPTQAVGAIIGKKGAHIKQLARFAGASIKI-APAEGPDVSERMVIITGPPEAQFKAQGRI 449

Query: 452 QNSVKQ 457
              +K+
Sbjct: 450 FGKLKE 455



 Score = 39.3 bits (90), Expect = 0.008
 Identities = 19/72 (26%), Positives = 39/72 (54%)

Query: 144 DCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRVV 203
           D  LR+L+     G IIG +G  IK + + TQ+ + + ++    + ++ V I   P+   
Sbjct: 193 DFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTS 252

Query: 204 ECIKIILDLISE 215
           E  ++IL+++ +
Sbjct: 253 EACRMILEIMQK 264



 Score = 39.3 bits (90), Expect = 0.008
 Identities = 36/165 (21%), Positives = 68/165 (41%), Gaps = 26/165 (15%)

Query: 33  FKRSRNTDEMVELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGP---ERILS 89
           F    +  E   + + + ++  GA+IGK G +IK L     AS+ +  + GP   ER++ 
Sbjct: 375 FPHHHSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVI 434

Query: 90  ISADIETIGEILKKIIPTLEEGLQLPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRL 149
           I+   E   +   +I   L+E                       N+ + K  +   E  +
Sbjct: 435 ITGPPEAQFKAQGRIFGKLKEE----------------------NFFNPK-EEVKLEAHI 471

Query: 150 LIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVL 194
            +  S AG +IG  G  + EL+  T   + + ++  P   + V++
Sbjct: 472 RVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDENEEVIV 516



 Score = 38.5 bits (88), Expect = 0.013
 Identities = 21/73 (28%), Positives = 38/73 (52%), Gaps = 3/73 (4%)

Query: 388 ITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGS---EDRIITITGTQDQI 444
           I  ++     L G +IGK G+ +K+I HE+G  I I    + S    +R IT+ GT +  
Sbjct: 275 IPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITVKGTVEAC 334

Query: 445 QNAQYLLQNSVKQ 457
            +A+  +   +++
Sbjct: 335 ASAEIEIMKKLRE 347



 Score = 38.1 bits (87), Expect = 0.017
 Identities = 20/77 (25%), Positives = 41/77 (53%), Gaps = 2/77 (2%)

Query: 388 ITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKI--DEPLEGSEDRIITITGTQDQIQ 445
           +   + +P   AG +IGKGG+ + ++++ + A + +  D+  + +E+ I+ I G     Q
Sbjct: 467 LEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDENEEVIVRIIGHFFASQ 526

Query: 446 NAQYLLQNSVKQYADVE 462
            AQ  ++  V+Q    E
Sbjct: 527 TAQRKIREIVQQVKQQE 543



 Score = 36.2 bits (82), Expect = 0.065
 Identities = 24/67 (35%), Positives = 32/67 (47%), Gaps = 7/67 (10%)

Query: 19  FGKRPAEDMEEEQAFKRSRNTDEMVELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSV 78
           FGK     ++EE  F         +E  I + S  AG VIGKGGK +  L+   +A V V
Sbjct: 450 FGK-----LKEENFFNPKEEVK--LEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIV 502

Query: 79  PDSSGPE 85
           P    P+
Sbjct: 503 PRDQTPD 509



 Score = 35.4 bits (80), Expect = 0.11
 Identities = 31/135 (22%), Positives = 56/135 (41%), Gaps = 10/135 (7%)

Query: 327 GRPGDRYDGMVGFSADETWDSAIDTWSPSEWQMAYEPQGGSGYDYSYAGGRGSYGDLGGP 386
           G   + Y   + +  DE      +  SPS  Q A      S       GG      +  P
Sbjct: 142 GHQFENYSFKISYIPDE------EVSSPSPPQRAQRGDHSSREQGHAPGGTSQARQIDFP 195

Query: 387 IITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKID-EPLEGSEDRIITITGTQDQIQ 445
           +   ++ +P    G+IIGK G  IK I  ++ + + I  +   G+ ++ +TI  T +   
Sbjct: 196 L---RILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTS 252

Query: 446 NAQYLLQNSVKQYAD 460
            A  ++   +++ AD
Sbjct: 253 EACRMILEIMQKEAD 267


>gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo
           sapiens]
          Length = 940

 Score = 53.5 bits (127), Expect = 4e-07
 Identities = 54/155 (34%), Positives = 60/155 (38%), Gaps = 23/155 (14%)

Query: 248 GRPVGFPMRGRGG------FDRMPPGRGGRPMPPSRRDYDDMSPRRGPPPPPPG-----R 296
           G P+  P  G GG          PP RGG P      D     P RG P P PG     R
Sbjct: 648 GGPMPGPHGGPGGPVGPRLLGPPPPPRGGDPFWDGPGDPMRGGPMRGGPGPGPGPYHRGR 707

Query: 297 GGRGGSRARNLPLPPPPPP----RGGDLMAYDRRGRPGDRYDGMVGFSADETWDSAIDTW 352
           GGRGG+       PPPPPP    RGG        GR G    GMVG       +      
Sbjct: 708 GGRGGNEP-----PPPPPPFRGARGGRSGGGPPNGRGGPG-GGMVGGGGHRPHEGPGGGM 761

Query: 353 SPSEWQMAYE-PQGGSGYDY-SYAGGRGSYGDLGG 385
             S     +E P GG G  +  + G  GS G  GG
Sbjct: 762 GNSSGHRPHEGPGGGMGSGHRPHEGPGGSMGGGGG 796



 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 46/165 (27%), Positives = 55/165 (33%), Gaps = 23/165 (13%)

Query: 244 DDRRGRPV-GFPMRGRGGFDRMPPGRGGRPMPPSRRDYDDMSPRRGPPPPPPGRGGRGGS 302
           D  RG P+ G P  G G + R   GRGG   PP    +      R    PP GRGG GG 
Sbjct: 685 DPMRGGPMRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGGG 744

Query: 303 RARNLPLPPPPPPRGGDLMAYDRRGRPGDRYDGMVGFSADETWDSAIDTWSPSEWQMAYE 362
                   P   P GG  M      RP +   G +G                      + 
Sbjct: 745 MVGGGGHRPHEGPGGG--MGNSSGHRPHEGPGGGMG--------------------SGHR 782

Query: 363 PQGGSGYDYSYAGGRGSYGDLGGPIITTQVTIPKDLAGSIIGKGG 407
           P  G G      GG   +   GG I       P +  G  +G GG
Sbjct: 783 PHEGPGGSMGGGGGHRPHEGPGGGISGGSGHRPHEGPGGGMGAGG 827



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 31/71 (43%), Positives = 31/71 (43%), Gaps = 24/71 (33%)

Query: 252 GFPMRGRGG---FDRMPPGRGGRPMPPSRRDYDDMSPRRGPPPPPPGRGGRGGSRARNLP 308
           GFP  G GG       PPG GG PMP          P  GP       GG  G R     
Sbjct: 628 GFPPGGPGGPKGMQHFPPGPGG-PMP---------GPHGGP-------GGPVGPRL---- 666

Query: 309 LPPPPPPRGGD 319
           L PPPPPRGGD
Sbjct: 667 LGPPPPPRGGD 677


>gi|156151396 heterogeneous nuclear ribonucleoprotein R isoform 3
           [Homo sapiens]
          Length = 535

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 48/143 (33%), Positives = 57/143 (39%), Gaps = 56/143 (39%)

Query: 217 PIKGRAQP-------YDPNFY------DETYDY------GGFTMMFDDRRGRPVGFPMRG 257
           PI+GR +        Y P++Y      D+ Y Y      GG+    D   G   G+ +RG
Sbjct: 347 PIRGRGRGGGRGGYGYPPDYYGYEDYYDDYYGYDYHDYRGGYE---DPYYGYDDGYAVRG 403

Query: 258 RGGFDRMPPGRGGRPMPPSRRDYDDMSPRRGPPPPPPGRG-----GRGGSRARNLPLPPP 312
           RGG      GRGGR                G PPPP GRG     GR G   R  PL PP
Sbjct: 404 RGG------GRGGR----------------GAPPPPRGRGAPPPRGRAGYSQRGAPLGPP 441

Query: 313 PPPRGGDLMAYDRRGRPGDRYDG 335
              RGG       RG P  +  G
Sbjct: 442 RGSRGG-------RGGPAQQQRG 457


>gi|156151394 heterogeneous nuclear ribonucleoprotein R isoform 1
           [Homo sapiens]
          Length = 636

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 48/143 (33%), Positives = 57/143 (39%), Gaps = 56/143 (39%)

Query: 217 PIKGRAQP-------YDPNFY------DETYDY------GGFTMMFDDRRGRPVGFPMRG 257
           PI+GR +        Y P++Y      D+ Y Y      GG+    D   G   G+ +RG
Sbjct: 448 PIRGRGRGGGRGGYGYPPDYYGYEDYYDDYYGYDYHDYRGGYE---DPYYGYDDGYAVRG 504

Query: 258 RGGFDRMPPGRGGRPMPPSRRDYDDMSPRRGPPPPPPGRG-----GRGGSRARNLPLPPP 312
           RGG      GRGGR                G PPPP GRG     GR G   R  PL PP
Sbjct: 505 RGG------GRGGR----------------GAPPPPRGRGAPPPRGRAGYSQRGAPLGPP 542

Query: 313 PPPRGGDLMAYDRRGRPGDRYDG 335
              RGG       RG P  +  G
Sbjct: 543 RGSRGG-------RGGPAQQQRG 558


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.138    0.415 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,307,426
Number of Sequences: 37866
Number of extensions: 1571721
Number of successful extensions: 16430
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 302
Number of HSP's successfully gapped in prelim test: 594
Number of HSP's that attempted gapping in prelim test: 8900
Number of HSP's gapped (non-prelim): 4716
length of query: 464
length of database: 18,247,518
effective HSP length: 106
effective length of query: 358
effective length of database: 14,233,722
effective search space: 5095672476
effective search space used: 5095672476
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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