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Search of human proteins with 9966799
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|9966799 UTP3, small subunit processome component [Homo
sapiens]
(479 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|9966799 UTP3, small subunit processome component [Homo sapiens] 941 0.0
gi|111038128 neuroguidin isoform 1 [Homo sapiens] 61 3e-09
gi|111038133 neuroguidin isoform 2 [Homo sapiens] 61 3e-09
gi|210032580 SET domain containing 1B [Homo sapiens] 59 7e-09
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 57 3e-08
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 57 3e-08
gi|4759128 solute carrier family 24 (sodium/potassium/calcium ex... 54 4e-07
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 50 5e-06
gi|187960109 RNA binding motif protein 28 [Homo sapiens] 49 8e-06
gi|225735631 mesoderm induction early response 1 isoform g [Homo... 48 2e-05
gi|225735619 mesoderm induction early response 1 isoform i [Homo... 48 2e-05
gi|225735617 mesoderm induction early response 1 isoform h [Homo... 48 2e-05
gi|225735615 mesoderm induction early response 1 isoform a [Homo... 48 2e-05
gi|118130872 mesoderm induction early response 1 isoform f [Homo... 48 2e-05
gi|225735612 mesoderm induction early response 1 isoform e [Homo... 48 2e-05
gi|225735610 mesoderm induction early response 1 isoform d [Homo... 48 2e-05
gi|118130815 mesoderm induction early response 1 isoform c [Homo... 48 2e-05
gi|225735607 mesoderm induction early response 1 isoform b [Homo... 48 2e-05
gi|225735605 mesoderm induction early response 1 isoform a [Homo... 48 2e-05
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 48 2e-05
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 48 2e-05
gi|5453880 acidic (leucine-rich) nuclear phosphoprotein 32 famil... 48 2e-05
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 48 2e-05
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 48 2e-05
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 48 2e-05
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 48 2e-05
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 48 2e-05
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 47 3e-05
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 47 3e-05
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 47 3e-05
>gi|9966799 UTP3, small subunit processome component [Homo sapiens]
Length = 479
Score = 941 bits (2431), Expect = 0.0
Identities = 479/479 (100%), Positives = 479/479 (100%)
Query: 1 MVGRSRRRGAAKWAAVRAKAGPTLTDENGDDLGLPPSPGDTSYYQDQVDDFHEARSRAAL 60
MVGRSRRRGAAKWAAVRAKAGPTLTDENGDDLGLPPSPGDTSYYQDQVDDFHEARSRAAL
Sbjct: 1 MVGRSRRRGAAKWAAVRAKAGPTLTDENGDDLGLPPSPGDTSYYQDQVDDFHEARSRAAL 60
Query: 61 AKGWNEVQSGDEEDGEEEEEEVLALDMDDEDDEDGGNAGEEEEEENADDDGGSSVQSEAE 120
AKGWNEVQSGDEEDGEEEEEEVLALDMDDEDDEDGGNAGEEEEEENADDDGGSSVQSEAE
Sbjct: 61 AKGWNEVQSGDEEDGEEEEEEVLALDMDDEDDEDGGNAGEEEEEENADDDGGSSVQSEAE 120
Query: 121 ASVDPSLSWGQRKKLYYDTDYGSKSRGRQSQQEAEEEEREEEEEAQIIQRRLAQALQEDD 180
ASVDPSLSWGQRKKLYYDTDYGSKSRGRQSQQEAEEEEREEEEEAQIIQRRLAQALQEDD
Sbjct: 121 ASVDPSLSWGQRKKLYYDTDYGSKSRGRQSQQEAEEEEREEEEEAQIIQRRLAQALQEDD 180
Query: 181 FGVAWVEAFAKPVPQVDEAETRVVKDLAKVSVKEKLKMLRKESPELLELIEDLKVKLTEV 240
FGVAWVEAFAKPVPQVDEAETRVVKDLAKVSVKEKLKMLRKESPELLELIEDLKVKLTEV
Sbjct: 181 FGVAWVEAFAKPVPQVDEAETRVVKDLAKVSVKEKLKMLRKESPELLELIEDLKVKLTEV 240
Query: 241 KDELEPLLELVEQGIIPPGKGSQYLRTKYNLYLNYCSNISFYLILKARRVPAHGHPVIER 300
KDELEPLLELVEQGIIPPGKGSQYLRTKYNLYLNYCSNISFYLILKARRVPAHGHPVIER
Sbjct: 241 KDELEPLLELVEQGIIPPGKGSQYLRTKYNLYLNYCSNISFYLILKARRVPAHGHPVIER 300
Query: 301 LVTYRNLINKLSVVDQKLSSEIRHLLTLKDDAVKKELIPKAKSTKPKPKSVSKTSAAACA 360
LVTYRNLINKLSVVDQKLSSEIRHLLTLKDDAVKKELIPKAKSTKPKPKSVSKTSAAACA
Sbjct: 301 LVTYRNLINKLSVVDQKLSSEIRHLLTLKDDAVKKELIPKAKSTKPKPKSVSKTSAAACA 360
Query: 361 VTDLSDDSDFDEKAKLKYYKEIEDRQKLKRKKEENSTEEQALEDQNAKRAITYQIAKNRG 420
VTDLSDDSDFDEKAKLKYYKEIEDRQKLKRKKEENSTEEQALEDQNAKRAITYQIAKNRG
Sbjct: 361 VTDLSDDSDFDEKAKLKYYKEIEDRQKLKRKKEENSTEEQALEDQNAKRAITYQIAKNRG 420
Query: 421 LTPRRKKIDRNPRVKHREKFRRAKIRRRGQVREVRKEEQRYSGELSGIRAGVKKSIKLK 479
LTPRRKKIDRNPRVKHREKFRRAKIRRRGQVREVRKEEQRYSGELSGIRAGVKKSIKLK
Sbjct: 421 LTPRRKKIDRNPRVKHREKFRRAKIRRRGQVREVRKEEQRYSGELSGIRAGVKKSIKLK 479
>gi|111038128 neuroguidin isoform 1 [Homo sapiens]
Length = 315
Score = 60.8 bits (146), Expect = 3e-09
Identities = 54/233 (23%), Positives = 101/233 (43%), Gaps = 12/233 (5%)
Query: 216 LKMLRKESPELLELIEDLKVKLTEVKDELEPLLELVEQGIIPPGKGSQYLRTKYNLYLNY 275
L +L + P + L+++L+ ++ V +++ L + V+ G P KG +L K L L Y
Sbjct: 4 LGVLESDLPSAVTLLKNLQEQVMAVTAQVKSLTQKVQAGAYPTEKGLSFLEVKDQLLLMY 63
Query: 276 CSNISFYLILKARRVPAHGHPVIERLVTYRNLINKLSVVDQKLSSEIRHLLTLKDDAVKK 335
+++ ++ KA GH + RLV R ++ KL +DQKL +I L+
Sbjct: 64 LMDLTHLILDKASGGSLQGHDAVLRLVEIRTVLEKLRPLDQKLKYQIDKLIKTAVTGSLS 123
Query: 336 ELIPKAKSTKPKPKSVSKTSAAACAVTDLSDDSDFDEKAKLKYYKEIEDRQKLKR----K 391
E P KP P ++ ++ D ++D D E + K K + + R
Sbjct: 124 ENDP--LRFKPHPSNMMSKLSSEDEEEDEAED-DQSEASGKKSVKGVSKKYVPPRLVPVH 180
Query: 392 KEENSTEEQALEDQNAKR-----AITYQIAKNRGLTPRRKKIDRNPRVKHREK 439
+E E + + AKR ++ ++ + P + R+P V + +
Sbjct: 181 YDETEAEREKKRLERAKRRALSSSVIRELKEQYSDAPEEIRDARHPHVTRQSQ 233
>gi|111038133 neuroguidin isoform 2 [Homo sapiens]
Length = 311
Score = 60.8 bits (146), Expect = 3e-09
Identities = 54/233 (23%), Positives = 101/233 (43%), Gaps = 12/233 (5%)
Query: 216 LKMLRKESPELLELIEDLKVKLTEVKDELEPLLELVEQGIIPPGKGSQYLRTKYNLYLNY 275
L +L + P + L+++L+ ++ V +++ L + V+ G P KG +L K L L Y
Sbjct: 4 LGVLESDLPSAVTLLKNLQEQVMAVTAQVKSLTQKVQAGAYPTEKGLSFLEVKDQLLLMY 63
Query: 276 CSNISFYLILKARRVPAHGHPVIERLVTYRNLINKLSVVDQKLSSEIRHLLTLKDDAVKK 335
+++ ++ KA GH + RLV R ++ KL +DQKL +I L+
Sbjct: 64 LMDLTHLILDKASGGSLQGHDAVLRLVEIRTVLEKLRPLDQKLKYQIDKLIKTAVTGSLS 123
Query: 336 ELIPKAKSTKPKPKSVSKTSAAACAVTDLSDDSDFDEKAKLKYYKEIEDRQKLKR----K 391
E P KP P ++ ++ D ++D D E + K K + + R
Sbjct: 124 ENDP--LRFKPHPSNMMSKLSSEDEEEDEAED-DQSEASGKKSVKGVSKKYVPPRLVPVH 180
Query: 392 KEENSTEEQALEDQNAKR-----AITYQIAKNRGLTPRRKKIDRNPRVKHREK 439
+E E + + AKR ++ ++ + P + R+P V + +
Sbjct: 181 YDETEAEREKKRLERAKRRALSSSVIRELKEQYSDAPEEIRDARHPHVTRQSQ 233
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 59.3 bits (142), Expect = 7e-09
Identities = 60/208 (28%), Positives = 87/208 (41%), Gaps = 29/208 (13%)
Query: 71 DEEDGEEEEEEVLALDMDDEDDEDGGNAGEEEEEENA-----DDDGGSSVQSEAEASVDP 125
+EE+ EEEEEE + DD+DD D + E ++E+ A + D G S + E + V
Sbjct: 1050 EEEEAEEEEEE----EDDDDDDSDDRDESENDDEDTALSEASEKDEGDSDEEETVSIVTS 1105
Query: 126 SLSWGQRKKLYYDTDYGSKSRGRQSQQE------AEEEEREEEEEAQIIQRRLAQALQED 179
+ +++ S S S E A EEE EEEEE + + +A A ED
Sbjct: 1106 KAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEEMVAEESMASAGPED 1165
Query: 180 DFGVAWVEAFAKPVPQVDEAETRVVKDLAKVSVKEKLKMLRKESPELLELIEDLKVKLTE 239
A A P VD D+ +V +E P +L+ L V + E
Sbjct: 1166 FEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAP------EERPSMLD-EPPLPVGVEE 1218
Query: 240 VKDELEPLLE--LVEQGII-----PPGK 260
D EP E L ++G + PP K
Sbjct: 1219 PADSREPPEEPGLSQEGAMLLSPEPPAK 1246
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 57.4 bits (137), Expect = 3e-08
Identities = 101/425 (23%), Positives = 171/425 (40%), Gaps = 68/425 (16%)
Query: 66 EVQSGDEEDGEEEEEEVLAL---------DMDDEDDEDGGNAGEEEEEENADDDGGSSVQ 116
E EE+ E EEEEV A ++ +E+ E G+EEEEE +D+G S Q
Sbjct: 490 EAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEE--EDEGAKSDQ 547
Query: 117 SEAEASVDPSLSWGQRKKLYYDTDYGSKSRGRQSQQEAEEEEREEEEEAQIIQRRLAQAL 176
+E G K+ + + G + G +++ EAE EE E +EE ++ ++ A
Sbjct: 548 AE---------EGGSEKEGSSEKEEGEQEEG-ETEAEAEGEEAEAKEEKKVEEKSEEVAT 597
Query: 177 QED---DFGVAWVEAFAKPVPQVDEAETRVVKDLAKVSVKEKLKMLRKESPELLELIEDL 233
+E+ D V E PVP+ E + + K V+EK K +SP +E+
Sbjct: 598 KEELVADAKVEKPEKAKSPVPK-SPVEEKGKSPVPKSPVEEKGKSPVPKSP-----VEE- 650
Query: 234 KVKLTEVKDELEPLLELVEQGIIPPGKGSQYLRTKYNLYLNYCSNISFYLILKARRVPAH 293
K K K +E E+G P K + K
Sbjct: 651 KGKSPVPKSPVE------EKGKSPVSKSPVEEKAK------------------------- 679
Query: 294 GHPVIERLVTYRNLINKLSVVDQKLSSEIRHLLTLKDDAV-KKELIPKAKSTKPKPKSVS 352
PV + V ++ +QK E K++ V KKE PK K K +S
Sbjct: 680 -SPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPV 738
Query: 353 KTSAAACAVTDLSDDSDFDEKAKLKYYKEIEDRQKLKRKKEENSTEEQALEDQNAKRAIT 412
K A A VT EK + K ++ ++ ++ E +EE+ D+ AK +
Sbjct: 739 KEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEG-SDKGAKGSRK 797
Query: 413 YQIAKNRGLTPRRKKIDRNPRVKHREKFRRAKIRRRGQVREVRKEEQRYSGELSGIRAGV 472
IA N G ++++++ + K + + G ++ +++ G+ S + V
Sbjct: 798 EDIAVN-GEVEGKEEVEQETKEKGSGREEEKGVVTNG--LDLSPADEKKGGDKSEEKVVV 854
Query: 473 KKSIK 477
K+++
Sbjct: 855 TKTVE 859
Score = 38.1 bits (87), Expect = 0.018
Identities = 56/250 (22%), Positives = 106/250 (42%), Gaps = 26/250 (10%)
Query: 10 AAKWAAVRAKAGPTLTDENGDDLGLPPSPGDTSYYQDQVDDFHEARSRAALAKGWNEVQS 69
AAK + V+A A P + +E G+ + +++ ++ A+S A G + S
Sbjct: 507 AAKKSPVKATA-PEVKEEEGEK-------EEEEGQEEEEEEDEGAKSDQAEEGGSEKEGS 558
Query: 70 GDEEDGEEEEEEVLALDMDDEDDEDGGNAGEEEEEENADDDGGSSVQSEAEASVDPSLSW 129
++E+GE+EE E A E + + A EE++ E ++ + + A+A V+
Sbjct: 559 SEKEEGEQEEGETEA-----EAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKP--- 610
Query: 130 GQRKKLYYDTDYGSKSRGRQSQQEAEEEERE-------EEEEAQIIQRRLAQALQEDDFG 182
+ K + K + + EE+ + EE+ + + + +
Sbjct: 611 EKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVS 670
Query: 183 VAWVEAFAK-PVPQVDEAETRVVKDLAKVSVKEKLKMLRKESP--ELLELIEDLKVKLTE 239
+ VE AK PVP+ E + ++ K KE+ + KE+P E +E E+ + E
Sbjct: 671 KSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPE 730
Query: 240 VKDELEPLLE 249
K P+ E
Sbjct: 731 KKKAESPVKE 740
Score = 32.0 bits (71), Expect = 1.3
Identities = 29/106 (27%), Positives = 54/106 (50%), Gaps = 18/106 (16%)
Query: 53 EARSRAALAKGWNEVQSGDEEDGEEEEEEVLALDMDDEDDEDGGNAGEEEEEENADDDGG 112
EA+S+A + KG E EEEE+EV +++ ++ + E++ A+
Sbjct: 689 EAKSKAEVGKG---------EQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAE---- 735
Query: 113 SSVQSEAEASVDPSLSWGQRKKLYYDTDYGSKSRGRQSQQEAEEEE 158
S V+ EA A V ++ + K++ + + +K G+ QQE E+E+
Sbjct: 736 SPVKEEAVAEV---VTITKSVKVHLEKE--TKEEGKPLQQEKEKEK 776
Score = 29.6 bits (65), Expect = 6.3
Identities = 28/153 (18%), Positives = 61/153 (39%), Gaps = 20/153 (13%)
Query: 76 EEEEEEVLALDMDDEDDEDGGNAGEEEEEENADDDGGSSVQSEAEASVDPSLSWGQRKKL 135
+E +EE L + E ++ GG G EEE GS ++ D +++ K
Sbjct: 759 KETKEEGKPLQQEKEKEKAGGEGGSEEE--------GSDKGAKGSRKEDIAVNGEVEGKE 810
Query: 136 YYDTDYGSKSRGRQSQQ----------EAEEEEREEEEEAQIIQRRLAQALQED--DFGV 183
+ + K GR+ ++ A+E++ ++ E +++ + + + + D
Sbjct: 811 EVEQETKEKGSGREEEKGVVTNGLDLSPADEKKGGDKSEEKVVVTKTVEKITSEGGDGAT 870
Query: 184 AWVEAFAKPVPQVDEAETRVVKDLAKVSVKEKL 216
++ +V+E E + L EK+
Sbjct: 871 KYITKSVTVTQKVEEHEETFEEKLVSTKKVEKV 903
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 57.4 bits (137), Expect = 3e-08
Identities = 101/425 (23%), Positives = 171/425 (40%), Gaps = 68/425 (16%)
Query: 66 EVQSGDEEDGEEEEEEVLAL---------DMDDEDDEDGGNAGEEEEEENADDDGGSSVQ 116
E EE+ E EEEEV A ++ +E+ E G+EEEEE +D+G S Q
Sbjct: 114 EAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEE--EDEGAKSDQ 171
Query: 117 SEAEASVDPSLSWGQRKKLYYDTDYGSKSRGRQSQQEAEEEEREEEEEAQIIQRRLAQAL 176
+E G K+ + + G + G +++ EAE EE E +EE ++ ++ A
Sbjct: 172 AE---------EGGSEKEGSSEKEEGEQEEG-ETEAEAEGEEAEAKEEKKVEEKSEEVAT 221
Query: 177 QED---DFGVAWVEAFAKPVPQVDEAETRVVKDLAKVSVKEKLKMLRKESPELLELIEDL 233
+E+ D V E PVP+ E + + K V+EK K +SP +E+
Sbjct: 222 KEELVADAKVEKPEKAKSPVPK-SPVEEKGKSPVPKSPVEEKGKSPVPKSP-----VEE- 274
Query: 234 KVKLTEVKDELEPLLELVEQGIIPPGKGSQYLRTKYNLYLNYCSNISFYLILKARRVPAH 293
K K K +E E+G P K + K
Sbjct: 275 KGKSPVPKSPVE------EKGKSPVSKSPVEEKAK------------------------- 303
Query: 294 GHPVIERLVTYRNLINKLSVVDQKLSSEIRHLLTLKDDAV-KKELIPKAKSTKPKPKSVS 352
PV + V ++ +QK E K++ V KKE PK K K +S
Sbjct: 304 -SPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPV 362
Query: 353 KTSAAACAVTDLSDDSDFDEKAKLKYYKEIEDRQKLKRKKEENSTEEQALEDQNAKRAIT 412
K A A VT EK + K ++ ++ ++ E +EE+ D+ AK +
Sbjct: 363 KEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEG-SDKGAKGSRK 421
Query: 413 YQIAKNRGLTPRRKKIDRNPRVKHREKFRRAKIRRRGQVREVRKEEQRYSGELSGIRAGV 472
IA N G ++++++ + K + + G ++ +++ G+ S + V
Sbjct: 422 EDIAVN-GEVEGKEEVEQETKEKGSGREEEKGVVTNG--LDLSPADEKKGGDKSEEKVVV 478
Query: 473 KKSIK 477
K+++
Sbjct: 479 TKTVE 483
Score = 38.1 bits (87), Expect = 0.018
Identities = 56/250 (22%), Positives = 106/250 (42%), Gaps = 26/250 (10%)
Query: 10 AAKWAAVRAKAGPTLTDENGDDLGLPPSPGDTSYYQDQVDDFHEARSRAALAKGWNEVQS 69
AAK + V+A A P + +E G+ + +++ ++ A+S A G + S
Sbjct: 131 AAKKSPVKATA-PEVKEEEGEK-------EEEEGQEEEEEEDEGAKSDQAEEGGSEKEGS 182
Query: 70 GDEEDGEEEEEEVLALDMDDEDDEDGGNAGEEEEEENADDDGGSSVQSEAEASVDPSLSW 129
++E+GE+EE E A E + + A EE++ E ++ + + A+A V+
Sbjct: 183 SEKEEGEQEEGETEA-----EAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKP--- 234
Query: 130 GQRKKLYYDTDYGSKSRGRQSQQEAEEEERE-------EEEEAQIIQRRLAQALQEDDFG 182
+ K + K + + EE+ + EE+ + + + +
Sbjct: 235 EKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVS 294
Query: 183 VAWVEAFAK-PVPQVDEAETRVVKDLAKVSVKEKLKMLRKESP--ELLELIEDLKVKLTE 239
+ VE AK PVP+ E + ++ K KE+ + KE+P E +E E+ + E
Sbjct: 295 KSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPE 354
Query: 240 VKDELEPLLE 249
K P+ E
Sbjct: 355 KKKAESPVKE 364
Score = 32.0 bits (71), Expect = 1.3
Identities = 29/106 (27%), Positives = 54/106 (50%), Gaps = 18/106 (16%)
Query: 53 EARSRAALAKGWNEVQSGDEEDGEEEEEEVLALDMDDEDDEDGGNAGEEEEEENADDDGG 112
EA+S+A + KG E EEEE+EV +++ ++ + E++ A+
Sbjct: 313 EAKSKAEVGKG---------EQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAE---- 359
Query: 113 SSVQSEAEASVDPSLSWGQRKKLYYDTDYGSKSRGRQSQQEAEEEE 158
S V+ EA A V ++ + K++ + + +K G+ QQE E+E+
Sbjct: 360 SPVKEEAVAEV---VTITKSVKVHLEKE--TKEEGKPLQQEKEKEK 400
Score = 29.6 bits (65), Expect = 6.3
Identities = 28/153 (18%), Positives = 61/153 (39%), Gaps = 20/153 (13%)
Query: 76 EEEEEEVLALDMDDEDDEDGGNAGEEEEEENADDDGGSSVQSEAEASVDPSLSWGQRKKL 135
+E +EE L + E ++ GG G EEE GS ++ D +++ K
Sbjct: 383 KETKEEGKPLQQEKEKEKAGGEGGSEEE--------GSDKGAKGSRKEDIAVNGEVEGKE 434
Query: 136 YYDTDYGSKSRGRQSQQ----------EAEEEEREEEEEAQIIQRRLAQALQED--DFGV 183
+ + K GR+ ++ A+E++ ++ E +++ + + + + D
Sbjct: 435 EVEQETKEKGSGREEEKGVVTNGLDLSPADEKKGGDKSEEKVVVTKTVEKITSEGGDGAT 494
Query: 184 AWVEAFAKPVPQVDEAETRVVKDLAKVSVKEKL 216
++ +V+E E + L EK+
Sbjct: 495 KYITKSVTVTQKVEEHEETFEEKLVSTKKVEKV 527
>gi|4759128 solute carrier family 24 (sodium/potassium/calcium
exchanger), member 1 [Homo sapiens]
Length = 1099
Score = 53.5 bits (127), Expect = 4e-07
Identities = 44/160 (27%), Positives = 72/160 (45%), Gaps = 13/160 (8%)
Query: 34 LPPSPGDTSYYQDQVDDFHEARSRAAL--------AKGWNEVQSGDEEDGE---EEEEEV 82
+P GD +D EA S + +G E +SG E E E E +
Sbjct: 730 VPDIKGDQKENPGGQEDVAEAESTGEMPGEEGETAGEGETEEKSGGETQPEGEGETETQG 789
Query: 83 LALDMDDEDDEDG--GNAGEEEEEENADDDGGSSVQSEAEASVDPSLSWGQRKKLYYDTD 140
+ +DE++ +G N GE+E E +A+D + E E+ + + G+ K +
Sbjct: 790 KGEECEDENEAEGKGDNEGEDEGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVE 849
Query: 141 YGSKSRGRQSQQEAEEEEREEEEEAQIIQRRLAQALQEDD 180
G S G S++E EEEE +EEEE + Q + +E++
Sbjct: 850 DGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEE 889
Score = 46.6 bits (109), Expect = 5e-05
Identities = 36/145 (24%), Positives = 59/145 (40%), Gaps = 17/145 (11%)
Query: 20 AGPTLTDENGDDLGLPPSPGDTSYYQDQVDDFHEARSRAALAKGWNEVQSGDEEDGEEEE 79
AG T+E P G+T E + + + NE + + +GE+E
Sbjct: 764 AGEGETEEKSGGETQPEGEGET-----------ETQGKGEECEDENEAEGKGDNEGEDEG 812
Query: 80 EEVLALDMDDEDDEDGGNAGEEEEEENADDDGGSSVQSEAEASVDPSLSWGQRKKLYYDT 139
E + ED E GN GE E +E + ++ G + E G ++ +
Sbjct: 813 E------IHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEE 866
Query: 140 DYGSKSRGRQSQQEAEEEEREEEEE 164
+ + + Q+E EEEE EEEE+
Sbjct: 867 EEQEEEEEEEEQEEEEEEEEEEEEK 891
Score = 38.5 bits (88), Expect = 0.014
Identities = 26/94 (27%), Positives = 43/94 (45%), Gaps = 14/94 (14%)
Query: 26 DENGDDLG--------LPPSPGDTSYYQDQVDDFHEARSRAALAKGWNEVQSGDEEDGEE 77
D G+D G + + G+T + ++ EA++ + GD E+ EE
Sbjct: 805 DNEGEDEGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEE 864
Query: 78 EEEEVLALDMDDEDDEDGGNAGEEEEEENADDDG 111
EEEE +E++E+ EEEEEE ++ G
Sbjct: 865 EEEE------QEEEEEEEEQEEEEEEEEEEEEKG 892
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 50.1 bits (118), Expect = 5e-06
Identities = 34/109 (31%), Positives = 51/109 (46%), Gaps = 4/109 (3%)
Query: 62 KGWNEVQSGD---EEDGEEEEEEVLALDMDDEDDEDGGNAGEEEEEENADDDG-GSSVQS 117
+G E + G+ EE+GE E EE +E+ E+G GEEEE E +DG G +
Sbjct: 892 EGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEE 951
Query: 118 EAEASVDPSLSWGQRKKLYYDTDYGSKSRGRQSQQEAEEEEREEEEEAQ 166
E E + G+ ++ + G + + E E EE E EEE +
Sbjct: 952 EGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGE 1000
Score = 48.5 bits (114), Expect = 1e-05
Identities = 32/113 (28%), Positives = 52/113 (46%), Gaps = 19/113 (16%)
Query: 70 GDEEDGEEEEEEVLALDMDDEDDEDGGNAGEEEEEENADDDGGSSVQSEAEASVDPSLSW 129
G+E +GE EEEE ++E +E+G GE EEE + +G + E E V+
Sbjct: 974 GEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEE--GEGEGEEEEEGEVEGEVE----- 1026
Query: 130 GQRKKLYYDTDYGSKSRGRQSQQEAEEEEREEEEEAQIIQRRLAQALQEDDFG 182
G + G ++E EEE E E+E + + R + +E++ G
Sbjct: 1027 ------------GEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEG 1067
Score = 47.8 bits (112), Expect = 2e-05
Identities = 31/104 (29%), Positives = 51/104 (49%), Gaps = 3/104 (2%)
Query: 62 KGWNEVQSGDEEDGEEEEEEVLALDMDDEDDEDGGNAGEEEEEENADDDGGSSVQSEAEA 121
+G E G+EE+GE EEEE ++ ++ +G GEE E E +++G + E E
Sbjct: 834 EGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEG 893
Query: 122 SVDPSLSWGQRKKLYYDTDYGSKSRGR-QSQQEAEEEEREEEEE 164
+ G+ ++ G + G + ++E EE E E EEE
Sbjct: 894 EGEEEEGEGEGEE--EGEGEGEEEEGEGKGEEEGEEGEGEGEEE 935
Score = 47.0 bits (110), Expect = 4e-05
Identities = 32/119 (26%), Positives = 53/119 (44%), Gaps = 1/119 (0%)
Query: 46 DQVDDFHEARSRAALAKGWNEVQSGDEEDGEEEEEEVLALDMDDEDDEDGGNAGEEEEEE 105
++ ++ E +G E G+EE+GE + EE +E+ E+G GEEEE E
Sbjct: 825 EREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGE 884
Query: 106 NADDDGGSSVQSEAEASVDPSLSWGQRKKLYYDTDYGSKSRGRQSQQEAEEEEREEEEE 164
++ G + E E G+ + + + + G + + E EEEE E E E
Sbjct: 885 GEGEEEGEG-EGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGE 942
Score = 46.2 bits (108), Expect = 7e-05
Identities = 34/139 (24%), Positives = 62/139 (44%), Gaps = 15/139 (10%)
Query: 39 GDTSYYQDQVDDFHEARSRAALAKGWNEVQSGDEEDGEEEEEEVLALDMDDEDDEDGGNA 98
G+ +++ + R++ G E G+EE+G+ EEEE + + E E+G
Sbjct: 707 GEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEE----EKEGEGKEEGEGE 762
Query: 99 ----------GEEEEEENAD-DDGGSSVQSEAEASVDPSLSWGQRKKLYYDTDYGSKSRG 147
GE ++EE A ++ G + E + + G+ K+ + + G G
Sbjct: 763 EVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEG 822
Query: 148 RQSQQEAEEEEREEEEEAQ 166
+ ++E EEE EEEE +
Sbjct: 823 KGEREEEEEEGEGEEEEGE 841
Score = 45.8 bits (107), Expect = 9e-05
Identities = 27/94 (28%), Positives = 48/94 (51%), Gaps = 7/94 (7%)
Query: 70 GDEEDGEEEEEEVLALDMDDEDDEDGGNAGEEEEEENADDDGGSSVQSEAEASVDPSLSW 129
G+EE+GEEE EE + E +E+G GEEEEE + + + E E +
Sbjct: 990 GEEEEGEEEGEE------EGEGEEEGEGEGEEEEEGEVEGE-VEGEEGEGEGEEEEGEEE 1042
Query: 130 GQRKKLYYDTDYGSKSRGRQSQQEAEEEEREEEE 163
G+ ++ + + ++R + ++E + +E EEE
Sbjct: 1043 GEEREKEGEGEENRRNREEEEEEEGKYQETGEEE 1076
Score = 45.4 bits (106), Expect = 1e-04
Identities = 33/116 (28%), Positives = 51/116 (43%), Gaps = 2/116 (1%)
Query: 53 EARSRAALAKGWNEVQSGDEEDGEEEEEEVLALDMDDEDDEDGGN-AGEEEEEENADDDG 111
E KG E + G+ E GEEEE E D + E +E+ G GEEEE E ++
Sbjct: 911 EGEEEEGEGKGEEEGEEGEGE-GEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEE 969
Query: 112 GSSVQSEAEASVDPSLSWGQRKKLYYDTDYGSKSRGRQSQQEAEEEEREEEEEAQI 167
G E E + G+ ++ + + + G + + EEE E E E ++
Sbjct: 970 GEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEV 1025
Score = 41.6 bits (96), Expect = 0.002
Identities = 30/117 (25%), Positives = 50/117 (42%), Gaps = 22/117 (18%)
Query: 68 QSGDEEDGEEEEEEVLALDMDDEDDEDGGNAGE-------EEEEENADDDGGSSVQSEAE 120
+ GD+ +GEEEE E + ++ + +GG E EEEE +++ G + E E
Sbjct: 789 EEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGE 848
Query: 121 ASVDPSLSWGQRKKLYYDTDYGSKSRGRQSQQEAEEEERE-----------EEEEAQ 166
+ G+ + + + G + + E EEEE E EEEE +
Sbjct: 849 GEEEEGEGKGEEE----GEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGE 901
Score = 41.2 bits (95), Expect = 0.002
Identities = 31/106 (29%), Positives = 49/106 (46%), Gaps = 12/106 (11%)
Query: 66 EVQSGDEEDGEEEEEEVLALDMDDEDDEDGGNAGEEEE-----EENADDDGGSSVQSEAE 120
E + +E +GE EEEE + E +E+G GEEEE EE ++ G + E E
Sbjct: 884 EGEGEEEGEGEGEEEE-----GEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGE 938
Query: 121 ASVDPSLSWGQRKKLYY--DTDYGSKSRGRQSQQEAEEEEREEEEE 164
+ G+ ++ + + + G + + E EE E E EEE
Sbjct: 939 GEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEE 984
Score = 40.4 bits (93), Expect = 0.004
Identities = 29/112 (25%), Positives = 48/112 (42%), Gaps = 1/112 (0%)
Query: 53 EARSRAALAKGWNEVQSGDEEDGE-EEEEEVLALDMDDEDDEDGGNAGEEEEEENADDDG 111
E R + EV+ G+ E+G+ E EEE + ++E+ E GE EEEE
Sbjct: 800 ETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGE 859
Query: 112 GSSVQSEAEASVDPSLSWGQRKKLYYDTDYGSKSRGRQSQQEAEEEEREEEE 163
+ E E + G+ ++ + + + G + + E E EE E E
Sbjct: 860 EEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGE 911
Score = 38.5 bits (88), Expect = 0.014
Identities = 29/112 (25%), Positives = 53/112 (47%), Gaps = 11/112 (9%)
Query: 62 KGWNEVQSGDEE---DGEEEEEEVLALDMDDEDDEDGGNAGEEEEEENADDDGGSSVQSE 118
+G E + G+EE +GE EEE + + E++E+G GE E EE G + E
Sbjct: 987 EGEGEEEEGEEEGEEEGEGEEEG----EGEGEEEEEGEVEGEVEGEEGE----GEGEEEE 1038
Query: 119 AEASVDPSLSWGQRKKLYYDTDYGSKSRGRQSQQEAEEEEREEEEEAQIIQR 170
E + G+ ++ + + + G+ + EE ER++ EE + + +
Sbjct: 1039 GEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEEYKKVSK 1090
Score = 37.0 bits (84), Expect = 0.040
Identities = 26/108 (24%), Positives = 45/108 (41%), Gaps = 14/108 (12%)
Query: 66 EVQSGDEEDGEEEEEEVLALDMDDEDDEDGGNAGEEEEEENADDDGGSSVQSE------- 118
E + + DGEE+E++ E +++ GEEE E +++G + E
Sbjct: 698 EKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKE 757
Query: 119 ----AEASVDPSLSWGQRKKLYYDTDYGSKSRGRQSQQEAEEEEREEE 162
E + G+RKK + G + +G + + E EE E E
Sbjct: 758 EGEGEEVEGEREKEEGERKK---EERAGKEEKGEEEGDQGEGEEEETE 802
Score = 37.0 bits (84), Expect = 0.040
Identities = 33/119 (27%), Positives = 52/119 (43%), Gaps = 22/119 (18%)
Query: 70 GDEEDGEEEEEEVLALDMDDEDDEDGGNA---GEEEEEE---NADDDG------------ 111
G+EE+GE E EE + ++E+ E G GE EEEE +++G
Sbjct: 878 GEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEG 937
Query: 112 -GSSVQSEAEASVDPSLSWGQRKKLYYDTDYGSKSRGRQSQQEAEEEERE---EEEEAQ 166
G E E + G+ ++ + + + G + + E EEEE E EEEE +
Sbjct: 938 EGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGE 996
Score = 34.7 bits (78), Expect = 0.20
Identities = 29/131 (22%), Positives = 60/131 (45%), Gaps = 8/131 (6%)
Query: 26 DENGDDLGLPPSPGDTSYYQDQVDDFHEARSRAALAKGWNEVQSGDEEDGEEEEEEVLAL 85
+E G++ G G+ +++ + E +G E + G+EE GEE E+E
Sbjct: 996 EEEGEEEGEGEEEGEGEGEEEEEGEV-EGEVEGEEGEGEGEEEEGEEE-GEEREKEGEGE 1053
Query: 86 D---MDDEDDEDGGNAGEEEEEENADDDGGSSVQSEAEASVDPSLSWGQRKKLYYDTDYG 142
+ +E++E+ G E EEEN DG + + + + S+ +G+ K +
Sbjct: 1054 ENRRNREEEEEEEGKYQETGEEENERQDG---EEYKKVSKIKGSVKYGKHKTYQKKSVTN 1110
Query: 143 SKSRGRQSQQE 153
++ G++ + +
Sbjct: 1111 TQGNGKEQRSK 1121
Score = 32.7 bits (73), Expect = 0.75
Identities = 43/208 (20%), Positives = 82/208 (39%), Gaps = 36/208 (17%)
Query: 44 YQDQVDDFHEARSRAALAKG----WNEVQSGDEE----DGEEEEEEVLALDMDDEDD--- 92
+ D+ + E + A +KG EV++ +E G +E+ E+L+ D+ D+ +
Sbjct: 579 FSDEEVEIPEEKEGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAEVSE 638
Query: 93 ---------EDG-----------GNAG-----EEEEEENADDDGGSSVQSEAEASVDPSL 127
EDG G++G +EE E+ D G ++ E + +
Sbjct: 639 GKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAE 698
Query: 128 SWGQRKKLYYDTDYGSKSRGRQSQQEAEEEEREEEEEAQIIQRRLAQALQEDDFGVAWVE 187
+K+ + + + +G Q ++ E EE EEE + + + +E+ G E
Sbjct: 699 KEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEE 758
Query: 188 AFAKPVPQVDEAETRVVKDLAKVSVKEK 215
+ V E E K + +EK
Sbjct: 759 GEGEEVEGEREKEEGERKKEERAGKEEK 786
>gi|187960109 RNA binding motif protein 28 [Homo sapiens]
Length = 759
Score = 49.3 bits (116), Expect = 8e-06
Identities = 44/176 (25%), Positives = 82/176 (46%), Gaps = 25/176 (14%)
Query: 52 HEARSRAALAKGWNEVQSGDEEDGEEEEEEVLALDMDDEDDEDGGNAGEEEEEENADDDG 111
HE++ + ++ K E EED EEEE + D DD+D+EDG E+EEEEN +
Sbjct: 210 HESKHQESVKKKGRE-----EEDMEEEENDD---DDDDDDEEDGVFDDEDEEEENIESKV 261
Query: 112 GSSVQSEAEASVDPSLSWGQRKKLYYDTDYGSKSRGRQSQQEAEEEEREEEEEAQIIQRR 171
VQ + A P+ S+++++ EE + ++ + + +
Sbjct: 262 TKPVQIQKRAVKRPA----------------PAKSSDHSEEDSDLEESDSIDDGEELAQS 305
Query: 172 LAQALQEDDFGVAWVEAFAKPVP-QVDEAETRVVKDLAKVSVKEKLKMLRKESPEL 226
+++D V + +P V+E +T +++L+ S +E+L L ++ EL
Sbjct: 306 DTSTEEQEDKAVQVSNKKKRKLPSDVNEGKTVFIRNLSFDSEEEELGELLQQFGEL 361
>gi|225735631 mesoderm induction early response 1 isoform g [Homo
sapiens]
Length = 470
Score = 48.1 bits (113), Expect = 2e-05
Identities = 33/101 (32%), Positives = 48/101 (47%), Gaps = 21/101 (20%)
Query: 72 EEDGEEEEEEVLALDMDDEDDEDGGNAGEEEEEENADDDGGSSVQSEAEASVDPSLSWGQ 131
EED EEEEEE D +D D++D E +EEN D G ++++ ++ DPS S
Sbjct: 100 EEDEEEEEEEEEGEDDEDADNDDNSGCSGENKEENIKDSSGQEDETQS-SNDDPSQSVAS 158
Query: 132 ---------RKKLYYDTDYGSKSRGRQSQQEAEEEEREEEE 163
R+ Y+DT+ E EEE E+E+
Sbjct: 159 QDAQEIIRPRRCKYFDTN-----------SEVEEESEEDED 188
>gi|225735619 mesoderm induction early response 1 isoform i [Homo
sapiens]
Length = 370
Score = 48.1 bits (113), Expect = 2e-05
Identities = 33/101 (32%), Positives = 48/101 (47%), Gaps = 21/101 (20%)
Query: 72 EEDGEEEEEEVLALDMDDEDDEDGGNAGEEEEEENADDDGGSSVQSEAEASVDPSLSWGQ 131
EED EEEEEE D +D D++D E +EEN D G ++++ ++ DPS S
Sbjct: 20 EEDEEEEEEEEEGEDDEDADNDDNSGCSGENKEENIKDSSGQEDETQS-SNDDPSQSVAS 78
Query: 132 ---------RKKLYYDTDYGSKSRGRQSQQEAEEEEREEEE 163
R+ Y+DT+ E EEE E+E+
Sbjct: 79 QDAQEIIRPRRCKYFDTN-----------SEVEEESEEDED 108
>gi|225735617 mesoderm induction early response 1 isoform h [Homo
sapiens]
Length = 485
Score = 48.1 bits (113), Expect = 2e-05
Identities = 33/101 (32%), Positives = 48/101 (47%), Gaps = 21/101 (20%)
Query: 72 EEDGEEEEEEVLALDMDDEDDEDGGNAGEEEEEENADDDGGSSVQSEAEASVDPSLSWGQ 131
EED EEEEEE D +D D++D E +EEN D G ++++ ++ DPS S
Sbjct: 56 EEDEEEEEEEEEGEDDEDADNDDNSGCSGENKEENIKDSSGQEDETQS-SNDDPSQSVAS 114
Query: 132 ---------RKKLYYDTDYGSKSRGRQSQQEAEEEEREEEE 163
R+ Y+DT+ E EEE E+E+
Sbjct: 115 QDAQEIIRPRRCKYFDTN-----------SEVEEESEEDED 144
>gi|225735615 mesoderm induction early response 1 isoform a [Homo
sapiens]
Length = 529
Score = 48.1 bits (113), Expect = 2e-05
Identities = 33/101 (32%), Positives = 48/101 (47%), Gaps = 21/101 (20%)
Query: 72 EEDGEEEEEEVLALDMDDEDDEDGGNAGEEEEEENADDDGGSSVQSEAEASVDPSLSWGQ 131
EED EEEEEE D +D D++D E +EEN D G ++++ ++ DPS S
Sbjct: 100 EEDEEEEEEEEEGEDDEDADNDDNSGCSGENKEENIKDSSGQEDETQS-SNDDPSQSVAS 158
Query: 132 ---------RKKLYYDTDYGSKSRGRQSQQEAEEEEREEEE 163
R+ Y+DT+ E EEE E+E+
Sbjct: 159 QDAQEIIRPRRCKYFDTN-----------SEVEEESEEDED 188
>gi|118130872 mesoderm induction early response 1 isoform f [Homo
sapiens]
Length = 433
Score = 48.1 bits (113), Expect = 2e-05
Identities = 33/101 (32%), Positives = 48/101 (47%), Gaps = 21/101 (20%)
Query: 72 EEDGEEEEEEVLALDMDDEDDEDGGNAGEEEEEENADDDGGSSVQSEAEASVDPSLSWGQ 131
EED EEEEEE D +D D++D E +EEN D G ++++ ++ DPS S
Sbjct: 83 EEDEEEEEEEEEGEDDEDADNDDNSGCSGENKEENIKDSSGQEDETQS-SNDDPSQSVAS 141
Query: 132 ---------RKKLYYDTDYGSKSRGRQSQQEAEEEEREEEE 163
R+ Y+DT+ E EEE E+E+
Sbjct: 142 QDAQEIIRPRRCKYFDTN-----------SEVEEESEEDED 171
>gi|225735612 mesoderm induction early response 1 isoform e [Homo
sapiens]
Length = 486
Score = 48.1 bits (113), Expect = 2e-05
Identities = 33/101 (32%), Positives = 48/101 (47%), Gaps = 21/101 (20%)
Query: 72 EEDGEEEEEEVLALDMDDEDDEDGGNAGEEEEEENADDDGGSSVQSEAEASVDPSLSWGQ 131
EED EEEEEE D +D D++D E +EEN D G ++++ ++ DPS S
Sbjct: 136 EEDEEEEEEEEEGEDDEDADNDDNSGCSGENKEENIKDSSGQEDETQS-SNDDPSQSVAS 194
Query: 132 ---------RKKLYYDTDYGSKSRGRQSQQEAEEEEREEEE 163
R+ Y+DT+ E EEE E+E+
Sbjct: 195 QDAQEIIRPRRCKYFDTN-----------SEVEEESEEDED 224
>gi|225735610 mesoderm induction early response 1 isoform d [Homo
sapiens]
Length = 450
Score = 48.1 bits (113), Expect = 2e-05
Identities = 33/101 (32%), Positives = 48/101 (47%), Gaps = 21/101 (20%)
Query: 72 EEDGEEEEEEVLALDMDDEDDEDGGNAGEEEEEENADDDGGSSVQSEAEASVDPSLSWGQ 131
EED EEEEEE D +D D++D E +EEN D G ++++ ++ DPS S
Sbjct: 100 EEDEEEEEEEEEGEDDEDADNDDNSGCSGENKEENIKDSSGQEDETQS-SNDDPSQSVAS 158
Query: 132 ---------RKKLYYDTDYGSKSRGRQSQQEAEEEEREEEE 163
R+ Y+DT+ E EEE E+E+
Sbjct: 159 QDAQEIIRPRRCKYFDTN-----------SEVEEESEEDED 188
>gi|118130815 mesoderm induction early response 1 isoform c [Homo
sapiens]
Length = 512
Score = 48.1 bits (113), Expect = 2e-05
Identities = 33/101 (32%), Positives = 48/101 (47%), Gaps = 21/101 (20%)
Query: 72 EEDGEEEEEEVLALDMDDEDDEDGGNAGEEEEEENADDDGGSSVQSEAEASVDPSLSWGQ 131
EED EEEEEE D +D D++D E +EEN D G ++++ ++ DPS S
Sbjct: 83 EEDEEEEEEEEEGEDDEDADNDDNSGCSGENKEENIKDSSGQEDETQS-SNDDPSQSVAS 141
Query: 132 ---------RKKLYYDTDYGSKSRGRQSQQEAEEEEREEEE 163
R+ Y+DT+ E EEE E+E+
Sbjct: 142 QDAQEIIRPRRCKYFDTN-----------SEVEEESEEDED 171
>gi|225735607 mesoderm induction early response 1 isoform b [Homo
sapiens]
Length = 565
Score = 48.1 bits (113), Expect = 2e-05
Identities = 33/101 (32%), Positives = 48/101 (47%), Gaps = 21/101 (20%)
Query: 72 EEDGEEEEEEVLALDMDDEDDEDGGNAGEEEEEENADDDGGSSVQSEAEASVDPSLSWGQ 131
EED EEEEEE D +D D++D E +EEN D G ++++ ++ DPS S
Sbjct: 136 EEDEEEEEEEEEGEDDEDADNDDNSGCSGENKEENIKDSSGQEDETQS-SNDDPSQSVAS 194
Query: 132 ---------RKKLYYDTDYGSKSRGRQSQQEAEEEEREEEE 163
R+ Y+DT+ E EEE E+E+
Sbjct: 195 QDAQEIIRPRRCKYFDTN-----------SEVEEESEEDED 224
>gi|225735605 mesoderm induction early response 1 isoform a [Homo
sapiens]
Length = 529
Score = 48.1 bits (113), Expect = 2e-05
Identities = 33/101 (32%), Positives = 48/101 (47%), Gaps = 21/101 (20%)
Query: 72 EEDGEEEEEEVLALDMDDEDDEDGGNAGEEEEEENADDDGGSSVQSEAEASVDPSLSWGQ 131
EED EEEEEE D +D D++D E +EEN D G ++++ ++ DPS S
Sbjct: 100 EEDEEEEEEEEEGEDDEDADNDDNSGCSGENKEENIKDSSGQEDETQS-SNDDPSQSVAS 158
Query: 132 ---------RKKLYYDTDYGSKSRGRQSQQEAEEEEREEEE 163
R+ Y+DT+ E EEE E+E+
Sbjct: 159 QDAQEIIRPRRCKYFDTN-----------SEVEEESEEDED 188
>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
Length = 770
Score = 48.1 bits (113), Expect = 2e-05
Identities = 39/138 (28%), Positives = 61/138 (44%), Gaps = 23/138 (16%)
Query: 44 YQDQVDDFHEARSRAALAKGWNEVQSGDEEDGEEE-EEEVLALDMDDEDDED-------- 94
Y D+V H +RS + E+ G + EE+ EE L D+ D D +
Sbjct: 210 YSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAES 269
Query: 95 ------GGNAGEEEEEENADDDGGSSVQSEAEASVDPSLSWGQRKKLYYDTDYGSKSRGR 148
G+ EEEEEE +++G +S +SE E + ++ +T S+
Sbjct: 270 SSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEE--------EEEEEEEETGSNSEEASE 321
Query: 149 QSQQEAEEEEREEEEEAQ 166
QS +E EEE E+EE +
Sbjct: 322 QSAEEVSEEEMSEDEERE 339
Score = 42.0 bits (97), Expect = 0.001
Identities = 32/122 (26%), Positives = 55/122 (45%), Gaps = 14/122 (11%)
Query: 66 EVQSGDEEDGEEEEEEVLALDMDDEDDEDGGNAGEEEEEENADDDGGSSVQSEAEASVDP 125
E S + G EEEEE ++E++E+G + E EEEE +++ S +E + +
Sbjct: 268 ESSSAESGSGSEEEEEE-----EEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQ 322
Query: 126 SLSWGQRKKLYYDTDYGSKS------RGRQSQQEAEEEEREEEEEAQIIQRRLAQALQED 179
S +++ D + +++ R + E EE EEE Q + AL E
Sbjct: 323 SAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQ---SSALTEG 379
Query: 180 DF 181
D+
Sbjct: 380 DY 381
Score = 40.0 bits (92), Expect = 0.005
Identities = 31/116 (26%), Positives = 51/116 (43%), Gaps = 1/116 (0%)
Query: 48 VDDFHEARSRAALAKGWNEVQSGDEEDGEEEEEEVLALDMDDEDDEDGGNAGEEEEEENA 107
+ D ++ + + A+ + E+ EEEEEE E+ E+ EEEEEE
Sbjct: 254 LQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETG 313
Query: 108 DDDGGSSVQSEAEASVDPSLSWGQRKKLYYDTDYGSKSRGRQSQQEAEEEEREEEE 163
+ +S QS E S + +S + ++ +SR + E+EE E E E
Sbjct: 314 SNSEEASEQSAEEVS-EEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGE 368
Score = 31.6 bits (70), Expect = 1.7
Identities = 21/104 (20%), Positives = 45/104 (43%), Gaps = 15/104 (14%)
Query: 371 DEKAKLKYYKEIEDRQKLKRKKEENSTEEQALE--------------DQNAKRAITYQIA 416
+EKA++K K +DR + EE + +E + + + I
Sbjct: 27 EEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRGEEDDSLAIK 86
Query: 417 KNRGLTPRRKKIDRNPRVKHREKFRRAKIRRRGQVREVRKEEQR 460
+ ++ R++K+ K +EK++ A+++ R R R E++
Sbjct: 87 PPQQMS-RKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQ 129
>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
Length = 780
Score = 48.1 bits (113), Expect = 2e-05
Identities = 39/138 (28%), Positives = 61/138 (44%), Gaps = 23/138 (16%)
Query: 44 YQDQVDDFHEARSRAALAKGWNEVQSGDEEDGEEE-EEEVLALDMDDEDDED-------- 94
Y D+V H +RS + E+ G + EE+ EE L D+ D D +
Sbjct: 220 YSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAES 279
Query: 95 ------GGNAGEEEEEENADDDGGSSVQSEAEASVDPSLSWGQRKKLYYDTDYGSKSRGR 148
G+ EEEEEE +++G +S +SE E + ++ +T S+
Sbjct: 280 SSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEE--------EEEEEEEETGSNSEEASE 331
Query: 149 QSQQEAEEEEREEEEEAQ 166
QS +E EEE E+EE +
Sbjct: 332 QSAEEVSEEEMSEDEERE 349
Score = 42.0 bits (97), Expect = 0.001
Identities = 32/122 (26%), Positives = 55/122 (45%), Gaps = 14/122 (11%)
Query: 66 EVQSGDEEDGEEEEEEVLALDMDDEDDEDGGNAGEEEEEENADDDGGSSVQSEAEASVDP 125
E S + G EEEEE ++E++E+G + E EEEE +++ S +E + +
Sbjct: 278 ESSSAESGSGSEEEEEE-----EEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQ 332
Query: 126 SLSWGQRKKLYYDTDYGSKS------RGRQSQQEAEEEEREEEEEAQIIQRRLAQALQED 179
S +++ D + +++ R + E EE EEE Q + AL E
Sbjct: 333 SAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQ---SSALTEG 389
Query: 180 DF 181
D+
Sbjct: 390 DY 391
Score = 40.0 bits (92), Expect = 0.005
Identities = 31/116 (26%), Positives = 51/116 (43%), Gaps = 1/116 (0%)
Query: 48 VDDFHEARSRAALAKGWNEVQSGDEEDGEEEEEEVLALDMDDEDDEDGGNAGEEEEEENA 107
+ D ++ + + A+ + E+ EEEEEE E+ E+ EEEEEE
Sbjct: 264 LQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETG 323
Query: 108 DDDGGSSVQSEAEASVDPSLSWGQRKKLYYDTDYGSKSRGRQSQQEAEEEEREEEE 163
+ +S QS E S + +S + ++ +SR + E+EE E E E
Sbjct: 324 SNSEEASEQSAEEVS-EEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGE 378
>gi|5453880 acidic (leucine-rich) nuclear phosphoprotein 32 family,
member A [Homo sapiens]
Length = 249
Score = 48.1 bits (113), Expect = 2e-05
Identities = 30/105 (28%), Positives = 55/105 (52%), Gaps = 18/105 (17%)
Query: 61 AKGWNEVQSGDEEDGEEEEEEVLALDMDDEDDEDGGNAGEEEE---EENADDDGGSSVQS 117
A+G+ E +EED +EEE + A ++DE+DED GEEE+ EE D++G + +
Sbjct: 160 AEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEGYNDGEV 219
Query: 118 EAEASVDPSLSWGQRKKLYYDTDYGSKSRGRQSQQEAEEEEREEE 162
+ E + + G + RG++ ++E E+E +++
Sbjct: 220 DDEED---------------EEELGEEERGQKRKREPEDEGEDDD 249
Score = 43.5 bits (101), Expect = 4e-04
Identities = 33/104 (31%), Positives = 51/104 (49%), Gaps = 6/104 (5%)
Query: 22 PTLTDENGDDLGLPPSP-GDTSYYQDQVDDFHEARSRAALAKGWNEVQSGDEEDGEEEEE 80
P LT +G D +P D Y + +DD E + V+ ++ED EEE E
Sbjct: 140 PQLTYLDGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGE 199
Query: 81 EVLALDMDDEDDEDGGNAG----EEEEEENADDDGGSSVQSEAE 120
E + ++E+DE+G N G EE+EEE +++ G + E E
Sbjct: 200 EE-DVSGEEEEDEEGYNDGEVDDEEDEEELGEEERGQKRKREPE 242
Score = 32.3 bits (72), Expect = 0.97
Identities = 24/78 (30%), Positives = 36/78 (46%), Gaps = 17/78 (21%)
Query: 40 DTSYYQDQVDDFHEARSRAALAKGWNEVQSGDEEDGEEEEEEVLALDMDDEDDED----- 94
D +D+ D+ E +G E SG+EE+ EE + ++DDE+DE+
Sbjct: 182 DAQVVEDEEDEDEEE-------EGEEEDVSGEEEEDEEGYNDG---EVDDEEDEEELGEE 231
Query: 95 --GGNAGEEEEEENADDD 110
G E E+E DDD
Sbjct: 232 ERGQKRKREPEDEGEDDD 249
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 48.1 bits (113), Expect = 2e-05
Identities = 39/138 (28%), Positives = 61/138 (44%), Gaps = 23/138 (16%)
Query: 44 YQDQVDDFHEARSRAALAKGWNEVQSGDEEDGEEE-EEEVLALDMDDEDDED-------- 94
Y D+V H +RS + E+ G + EE+ EE L D+ D D +
Sbjct: 211 YSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAES 270
Query: 95 ------GGNAGEEEEEENADDDGGSSVQSEAEASVDPSLSWGQRKKLYYDTDYGSKSRGR 148
G+ EEEEEE +++G +S +SE E + ++ +T S+
Sbjct: 271 SSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEE--------EEEEEEEETGSNSEEASE 322
Query: 149 QSQQEAEEEEREEEEEAQ 166
QS +E EEE E+EE +
Sbjct: 323 QSAEEVSEEEMSEDEERE 340
Score = 42.0 bits (97), Expect = 0.001
Identities = 32/122 (26%), Positives = 55/122 (45%), Gaps = 14/122 (11%)
Query: 66 EVQSGDEEDGEEEEEEVLALDMDDEDDEDGGNAGEEEEEENADDDGGSSVQSEAEASVDP 125
E S + G EEEEE ++E++E+G + E EEEE +++ S +E + +
Sbjct: 269 ESSSAESGSGSEEEEEE-----EEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQ 323
Query: 126 SLSWGQRKKLYYDTDYGSKS------RGRQSQQEAEEEEREEEEEAQIIQRRLAQALQED 179
S +++ D + +++ R + E EE EEE Q + AL E
Sbjct: 324 SAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQ---SSALTEG 380
Query: 180 DF 181
D+
Sbjct: 381 DY 382
Score = 40.0 bits (92), Expect = 0.005
Identities = 31/116 (26%), Positives = 51/116 (43%), Gaps = 1/116 (0%)
Query: 48 VDDFHEARSRAALAKGWNEVQSGDEEDGEEEEEEVLALDMDDEDDEDGGNAGEEEEEENA 107
+ D ++ + + A+ + E+ EEEEEE E+ E+ EEEEEE
Sbjct: 255 LQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETG 314
Query: 108 DDDGGSSVQSEAEASVDPSLSWGQRKKLYYDTDYGSKSRGRQSQQEAEEEEREEEE 163
+ +S QS E S + +S + ++ +SR + E+EE E E E
Sbjct: 315 SNSEEASEQSAEEVS-EEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGE 369
Score = 32.7 bits (73), Expect = 0.75
Identities = 51/265 (19%), Positives = 110/265 (41%), Gaps = 28/265 (10%)
Query: 6 RRRGAAKWAAVRAKAGPTLTDENGDDLGLPPSPGDTSYYQDQVDDFHE----ARSRAALA 61
R+ +A+ ++ + +G +E ++ S + S +++ ++ E + S A
Sbjct: 263 RKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASE 322
Query: 62 KGWNEVQSGD-EEDGEEEEEEVLALDMDDEDDEDGGNAGEEEEEENADDDGGSSVQSEAE 120
+ EV + ED E E E L + + D D G + E EEE S++
Sbjct: 323 QSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDY 382
Query: 121 ASVDPSLSWGQRKKLYYDTDYGSKSRGRQSQQEAEEEEREEEEEAQIIQRRLAQALQEDD 180
P+LS + K+ Y +G +S +E + R EE ++ R A+ + D+
Sbjct: 383 VPDSPALSPIELKQEL--PKYLPALQGCRSVEEFQCLNRIEEGTYGVVYR--AKDKKTDE 438
Query: 181 FGVAWVEAFAKPVPQVDEAETRVVKDLAKVSVKEKLKMLRKESPELLEL--------IED 232
K + E E + L +++ +L+ + P ++ + ++
Sbjct: 439 I------VALKRLKMEKEKEGFPITSLREINT-----ILKAQHPNIVTVREIVVGSNMDK 487
Query: 233 LKVKLTEVKDELEPLLELVEQGIIP 257
+ + + V+ +L+ L+E ++Q +P
Sbjct: 488 IYIVMNYVEHDLKSLMETMKQPFLP 512
Score = 29.6 bits (65), Expect = 6.3
Identities = 25/113 (22%), Positives = 49/113 (43%), Gaps = 23/113 (20%)
Query: 371 DEKAKLKYYKEIEDRQKLKRKKE--------------------ENSTEEQALEDQNAKRA 410
+EKA++K K +DR + E E+S E++ ED +
Sbjct: 27 EEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRGEEDDSLAIK 86
Query: 411 ITYQIAKNRGLTPR---RKKIDRNPRVKHREKFRRAKIRRRGQVREVRKEEQR 460
Q+++ + R ++K ++ RVK +E+ + R R + + R+E +R
Sbjct: 87 PPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARREWER 139
>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
8 [Homo sapiens]
Length = 780
Score = 48.1 bits (113), Expect = 2e-05
Identities = 39/138 (28%), Positives = 61/138 (44%), Gaps = 23/138 (16%)
Query: 44 YQDQVDDFHEARSRAALAKGWNEVQSGDEEDGEEE-EEEVLALDMDDEDDED-------- 94
Y D+V H +RS + E+ G + EE+ EE L D+ D D +
Sbjct: 220 YSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAES 279
Query: 95 ------GGNAGEEEEEENADDDGGSSVQSEAEASVDPSLSWGQRKKLYYDTDYGSKSRGR 148
G+ EEEEEE +++G +S +SE E + ++ +T S+
Sbjct: 280 SSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEE--------EEEEEEEETGSNSEEASE 331
Query: 149 QSQQEAEEEEREEEEEAQ 166
QS +E EEE E+EE +
Sbjct: 332 QSAEEVSEEEMSEDEERE 349
Score = 42.0 bits (97), Expect = 0.001
Identities = 32/122 (26%), Positives = 55/122 (45%), Gaps = 14/122 (11%)
Query: 66 EVQSGDEEDGEEEEEEVLALDMDDEDDEDGGNAGEEEEEENADDDGGSSVQSEAEASVDP 125
E S + G EEEEE ++E++E+G + E EEEE +++ S +E + +
Sbjct: 278 ESSSAESGSGSEEEEEE-----EEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQ 332
Query: 126 SLSWGQRKKLYYDTDYGSKS------RGRQSQQEAEEEEREEEEEAQIIQRRLAQALQED 179
S +++ D + +++ R + E EE EEE Q + AL E
Sbjct: 333 SAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQ---SSALTEG 389
Query: 180 DF 181
D+
Sbjct: 390 DY 391
Score = 40.0 bits (92), Expect = 0.005
Identities = 31/116 (26%), Positives = 51/116 (43%), Gaps = 1/116 (0%)
Query: 48 VDDFHEARSRAALAKGWNEVQSGDEEDGEEEEEEVLALDMDDEDDEDGGNAGEEEEEENA 107
+ D ++ + + A+ + E+ EEEEEE E+ E+ EEEEEE
Sbjct: 264 LQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETG 323
Query: 108 DDDGGSSVQSEAEASVDPSLSWGQRKKLYYDTDYGSKSRGRQSQQEAEEEEREEEE 163
+ +S QS E S + +S + ++ +SR + E+EE E E E
Sbjct: 324 SNSEEASEQSAEEVS-EEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGE 378
Score = 32.7 bits (73), Expect = 0.75
Identities = 51/265 (19%), Positives = 110/265 (41%), Gaps = 28/265 (10%)
Query: 6 RRRGAAKWAAVRAKAGPTLTDENGDDLGLPPSPGDTSYYQDQVDDFHE----ARSRAALA 61
R+ +A+ ++ + +G +E ++ S + S +++ ++ E + S A
Sbjct: 272 RKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASE 331
Query: 62 KGWNEVQSGD-EEDGEEEEEEVLALDMDDEDDEDGGNAGEEEEEENADDDGGSSVQSEAE 120
+ EV + ED E E E L + + D D G + E EEE S++
Sbjct: 332 QSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDY 391
Query: 121 ASVDPSLSWGQRKKLYYDTDYGSKSRGRQSQQEAEEEEREEEEEAQIIQRRLAQALQEDD 180
P+LS + K+ Y +G +S +E + R EE ++ R A+ + D+
Sbjct: 392 VPDSPALSPIELKQEL--PKYLPALQGCRSVEEFQCLNRIEEGTYGVVYR--AKDKKTDE 447
Query: 181 FGVAWVEAFAKPVPQVDEAETRVVKDLAKVSVKEKLKMLRKESPELLEL--------IED 232
K + E E + L +++ +L+ + P ++ + ++
Sbjct: 448 I------VALKRLKMEKEKEGFPITSLREINT-----ILKAQHPNIVTVREIVVGSNMDK 496
Query: 233 LKVKLTEVKDELEPLLELVEQGIIP 257
+ + + V+ +L+ L+E ++Q +P
Sbjct: 497 IYIVMNYVEHDLKSLMETMKQPFLP 521
Score = 29.6 bits (65), Expect = 6.3
Identities = 25/113 (22%), Positives = 49/113 (43%), Gaps = 23/113 (20%)
Query: 371 DEKAKLKYYKEIEDRQKLKRKKE--------------------ENSTEEQALEDQNAKRA 410
+EKA++K K +DR + E E+S E++ ED +
Sbjct: 27 EEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRGEEDDSLAIK 86
Query: 411 ITYQIAKNRGLTPR---RKKIDRNPRVKHREKFRRAKIRRRGQVREVRKEEQR 460
Q+++ + R ++K ++ RVK +E+ + R R + + R+E +R
Sbjct: 87 PPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARREWER 139
>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
5 [Homo sapiens]
Length = 748
Score = 48.1 bits (113), Expect = 2e-05
Identities = 39/138 (28%), Positives = 61/138 (44%), Gaps = 23/138 (16%)
Query: 44 YQDQVDDFHEARSRAALAKGWNEVQSGDEEDGEEE-EEEVLALDMDDEDDED-------- 94
Y D+V H +RS + E+ G + EE+ EE L D+ D D +
Sbjct: 188 YSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAES 247
Query: 95 ------GGNAGEEEEEENADDDGGSSVQSEAEASVDPSLSWGQRKKLYYDTDYGSKSRGR 148
G+ EEEEEE +++G +S +SE E + ++ +T S+
Sbjct: 248 SSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEE--------EEEEEEEETGSNSEEASE 299
Query: 149 QSQQEAEEEEREEEEEAQ 166
QS +E EEE E+EE +
Sbjct: 300 QSAEEVSEEEMSEDEERE 317
Score = 42.0 bits (97), Expect = 0.001
Identities = 32/122 (26%), Positives = 55/122 (45%), Gaps = 14/122 (11%)
Query: 66 EVQSGDEEDGEEEEEEVLALDMDDEDDEDGGNAGEEEEEENADDDGGSSVQSEAEASVDP 125
E S + G EEEEE ++E++E+G + E EEEE +++ S +E + +
Sbjct: 246 ESSSAESGSGSEEEEEE-----EEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQ 300
Query: 126 SLSWGQRKKLYYDTDYGSKS------RGRQSQQEAEEEEREEEEEAQIIQRRLAQALQED 179
S +++ D + +++ R + E EE EEE Q + AL E
Sbjct: 301 SAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQ---SSALTEG 357
Query: 180 DF 181
D+
Sbjct: 358 DY 359
Score = 40.0 bits (92), Expect = 0.005
Identities = 31/116 (26%), Positives = 51/116 (43%), Gaps = 1/116 (0%)
Query: 48 VDDFHEARSRAALAKGWNEVQSGDEEDGEEEEEEVLALDMDDEDDEDGGNAGEEEEEENA 107
+ D ++ + + A+ + E+ EEEEEE E+ E+ EEEEEE
Sbjct: 232 LQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETG 291
Query: 108 DDDGGSSVQSEAEASVDPSLSWGQRKKLYYDTDYGSKSRGRQSQQEAEEEEREEEE 163
+ +S QS E S + +S + ++ +SR + E+EE E E E
Sbjct: 292 SNSEEASEQSAEEVS-EEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGE 346
Score = 32.7 bits (73), Expect = 0.75
Identities = 51/265 (19%), Positives = 110/265 (41%), Gaps = 28/265 (10%)
Query: 6 RRRGAAKWAAVRAKAGPTLTDENGDDLGLPPSPGDTSYYQDQVDDFHE----ARSRAALA 61
R+ +A+ ++ + +G +E ++ S + S +++ ++ E + S A
Sbjct: 240 RKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASE 299
Query: 62 KGWNEVQSGD-EEDGEEEEEEVLALDMDDEDDEDGGNAGEEEEEENADDDGGSSVQSEAE 120
+ EV + ED E E E L + + D D G + E EEE S++
Sbjct: 300 QSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDY 359
Query: 121 ASVDPSLSWGQRKKLYYDTDYGSKSRGRQSQQEAEEEEREEEEEAQIIQRRLAQALQEDD 180
P+LS + K+ Y +G +S +E + R EE ++ R A+ + D+
Sbjct: 360 VPDSPALSPIELKQEL--PKYLPALQGCRSVEEFQCLNRIEEGTYGVVYR--AKDKKTDE 415
Query: 181 FGVAWVEAFAKPVPQVDEAETRVVKDLAKVSVKEKLKMLRKESPELLEL--------IED 232
K + E E + L +++ +L+ + P ++ + ++
Sbjct: 416 I------VALKRLKMEKEKEGFPITSLREINT-----ILKAQHPNIVTVREIVVGSNMDK 464
Query: 233 LKVKLTEVKDELEPLLELVEQGIIP 257
+ + + V+ +L+ L+E ++Q +P
Sbjct: 465 IYIVMNYVEHDLKSLMETMKQPFLP 489
Score = 29.6 bits (65), Expect = 6.3
Identities = 21/96 (21%), Positives = 45/96 (46%), Gaps = 3/96 (3%)
Query: 364 LSDDSDFDEKAKLKYYKEIEDRQKLKRKKEENSTEEQALEDQNAKRAITYQIAKNRGLTP 423
+ D + D+ +K +++ ++K+ +K+E E++ +A+ + K +
Sbjct: 39 MEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKRRHRSHSAEGG-KHARVKEKEREH 97
Query: 424 RRKKIDRNPRVKHREKFRRAKIRRRGQVREVRKEEQ 459
R+K R + K R ++ R K RR RE + E+
Sbjct: 98 ERRKRHREEQDKARREWERQK--RREMAREHSRRER 131
>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
4 [Homo sapiens]
Length = 737
Score = 48.1 bits (113), Expect = 2e-05
Identities = 39/138 (28%), Positives = 61/138 (44%), Gaps = 23/138 (16%)
Query: 44 YQDQVDDFHEARSRAALAKGWNEVQSGDEEDGEEE-EEEVLALDMDDEDDED-------- 94
Y D+V H +RS + E+ G + EE+ EE L D+ D D +
Sbjct: 177 YSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAES 236
Query: 95 ------GGNAGEEEEEENADDDGGSSVQSEAEASVDPSLSWGQRKKLYYDTDYGSKSRGR 148
G+ EEEEEE +++G +S +SE E + ++ +T S+
Sbjct: 237 SSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEE--------EEEEEEEETGSNSEEASE 288
Query: 149 QSQQEAEEEEREEEEEAQ 166
QS +E EEE E+EE +
Sbjct: 289 QSAEEVSEEEMSEDEERE 306
Score = 42.0 bits (97), Expect = 0.001
Identities = 32/122 (26%), Positives = 55/122 (45%), Gaps = 14/122 (11%)
Query: 66 EVQSGDEEDGEEEEEEVLALDMDDEDDEDGGNAGEEEEEENADDDGGSSVQSEAEASVDP 125
E S + G EEEEE ++E++E+G + E EEEE +++ S +E + +
Sbjct: 235 ESSSAESGSGSEEEEEE-----EEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQ 289
Query: 126 SLSWGQRKKLYYDTDYGSKS------RGRQSQQEAEEEEREEEEEAQIIQRRLAQALQED 179
S +++ D + +++ R + E EE EEE Q + AL E
Sbjct: 290 SAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQ---SSALTEG 346
Query: 180 DF 181
D+
Sbjct: 347 DY 348
Score = 40.0 bits (92), Expect = 0.005
Identities = 31/116 (26%), Positives = 51/116 (43%), Gaps = 1/116 (0%)
Query: 48 VDDFHEARSRAALAKGWNEVQSGDEEDGEEEEEEVLALDMDDEDDEDGGNAGEEEEEENA 107
+ D ++ + + A+ + E+ EEEEEE E+ E+ EEEEEE
Sbjct: 221 LQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETG 280
Query: 108 DDDGGSSVQSEAEASVDPSLSWGQRKKLYYDTDYGSKSRGRQSQQEAEEEEREEEE 163
+ +S QS E S + +S + ++ +SR + E+EE E E E
Sbjct: 281 SNSEEASEQSAEEVS-EEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGE 335
Score = 32.7 bits (73), Expect = 0.75
Identities = 51/265 (19%), Positives = 110/265 (41%), Gaps = 28/265 (10%)
Query: 6 RRRGAAKWAAVRAKAGPTLTDENGDDLGLPPSPGDTSYYQDQVDDFHE----ARSRAALA 61
R+ +A+ ++ + +G +E ++ S + S +++ ++ E + S A
Sbjct: 229 RKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASE 288
Query: 62 KGWNEVQSGD-EEDGEEEEEEVLALDMDDEDDEDGGNAGEEEEEENADDDGGSSVQSEAE 120
+ EV + ED E E E L + + D D G + E EEE S++
Sbjct: 289 QSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDY 348
Query: 121 ASVDPSLSWGQRKKLYYDTDYGSKSRGRQSQQEAEEEEREEEEEAQIIQRRLAQALQEDD 180
P+LS + K+ Y +G +S +E + R EE ++ R A+ + D+
Sbjct: 349 VPDSPALSPIELKQEL--PKYLPALQGCRSVEEFQCLNRIEEGTYGVVYR--AKDKKTDE 404
Query: 181 FGVAWVEAFAKPVPQVDEAETRVVKDLAKVSVKEKLKMLRKESPELLEL--------IED 232
K + E E + L +++ +L+ + P ++ + ++
Sbjct: 405 I------VALKRLKMEKEKEGFPITSLREINT-----ILKAQHPNIVTVREIVVGSNMDK 453
Query: 233 LKVKLTEVKDELEPLLELVEQGIIP 257
+ + + V+ +L+ L+E ++Q +P
Sbjct: 454 IYIVMNYVEHDLKSLMETMKQPFLP 478
>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
2 [Homo sapiens]
Length = 782
Score = 48.1 bits (113), Expect = 2e-05
Identities = 39/138 (28%), Positives = 61/138 (44%), Gaps = 23/138 (16%)
Query: 44 YQDQVDDFHEARSRAALAKGWNEVQSGDEEDGEEE-EEEVLALDMDDEDDED-------- 94
Y D+V H +RS + E+ G + EE+ EE L D+ D D +
Sbjct: 222 YSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAES 281
Query: 95 ------GGNAGEEEEEENADDDGGSSVQSEAEASVDPSLSWGQRKKLYYDTDYGSKSRGR 148
G+ EEEEEE +++G +S +SE E + ++ +T S+
Sbjct: 282 SSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEE--------EEEEEEEETGSNSEEASE 333
Query: 149 QSQQEAEEEEREEEEEAQ 166
QS +E EEE E+EE +
Sbjct: 334 QSAEEVSEEEMSEDEERE 351
Score = 42.0 bits (97), Expect = 0.001
Identities = 32/122 (26%), Positives = 55/122 (45%), Gaps = 14/122 (11%)
Query: 66 EVQSGDEEDGEEEEEEVLALDMDDEDDEDGGNAGEEEEEENADDDGGSSVQSEAEASVDP 125
E S + G EEEEE ++E++E+G + E EEEE +++ S +E + +
Sbjct: 280 ESSSAESGSGSEEEEEE-----EEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQ 334
Query: 126 SLSWGQRKKLYYDTDYGSKS------RGRQSQQEAEEEEREEEEEAQIIQRRLAQALQED 179
S +++ D + +++ R + E EE EEE Q + AL E
Sbjct: 335 SAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQ---SSALTEG 391
Query: 180 DF 181
D+
Sbjct: 392 DY 393
Score = 40.0 bits (92), Expect = 0.005
Identities = 31/116 (26%), Positives = 51/116 (43%), Gaps = 1/116 (0%)
Query: 48 VDDFHEARSRAALAKGWNEVQSGDEEDGEEEEEEVLALDMDDEDDEDGGNAGEEEEEENA 107
+ D ++ + + A+ + E+ EEEEEE E+ E+ EEEEEE
Sbjct: 266 LQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETG 325
Query: 108 DDDGGSSVQSEAEASVDPSLSWGQRKKLYYDTDYGSKSRGRQSQQEAEEEEREEEE 163
+ +S QS E S + +S + ++ +SR + E+EE E E E
Sbjct: 326 SNSEEASEQSAEEVS-EEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGE 380
Score = 32.7 bits (73), Expect = 0.75
Identities = 51/265 (19%), Positives = 110/265 (41%), Gaps = 28/265 (10%)
Query: 6 RRRGAAKWAAVRAKAGPTLTDENGDDLGLPPSPGDTSYYQDQVDDFHE----ARSRAALA 61
R+ +A+ ++ + +G +E ++ S + S +++ ++ E + S A
Sbjct: 274 RKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASE 333
Query: 62 KGWNEVQSGD-EEDGEEEEEEVLALDMDDEDDEDGGNAGEEEEEENADDDGGSSVQSEAE 120
+ EV + ED E E E L + + D D G + E EEE S++
Sbjct: 334 QSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDY 393
Query: 121 ASVDPSLSWGQRKKLYYDTDYGSKSRGRQSQQEAEEEEREEEEEAQIIQRRLAQALQEDD 180
P+LS + K+ Y +G +S +E + R EE ++ R A+ + D+
Sbjct: 394 VPDSPALSPIELKQEL--PKYLPALQGCRSVEEFQCLNRIEEGTYGVVYR--AKDKKTDE 449
Query: 181 FGVAWVEAFAKPVPQVDEAETRVVKDLAKVSVKEKLKMLRKESPELLEL--------IED 232
K + E E + L +++ +L+ + P ++ + ++
Sbjct: 450 I------VALKRLKMEKEKEGFPITSLREINT-----ILKAQHPNIVTVREIVVGSNMDK 498
Query: 233 LKVKLTEVKDELEPLLELVEQGIIP 257
+ + + V+ +L+ L+E ++Q +P
Sbjct: 499 IYIVMNYVEHDLKSLMETMKQPFLP 523
Score = 30.8 bits (68), Expect = 2.8
Identities = 28/145 (19%), Positives = 64/145 (44%), Gaps = 4/145 (2%)
Query: 315 DQKLSSEIRHLLTLKDDAVKKELIPKAKSTKPKPKSVSKTSAAACAVTDLSDDSDFDEKA 374
+Q+ +EI+ L D K++ + + + + + + S + D + D+
Sbjct: 25 EQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYR-REDSMEDRGEEDDSL 83
Query: 375 KLKYYKEIEDRQKLKRKKEENSTEEQALEDQNAKRAITYQIAKNRGLTPRRKKIDRNPRV 434
+K +++ ++K+ +K+E E++ +A+ + K + R+K R +
Sbjct: 84 AIKPPQQMSRKEKVHHRKDEKRKEKRRHRSHSAEGG-KHARVKEKEREHERRKRHREEQD 142
Query: 435 KHREKFRRAKIRRRGQVREVRKEEQ 459
K R ++ R K RR RE + E+
Sbjct: 143 KARREWERQK--RREMAREHSRRER 165
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 47.4 bits (111), Expect = 3e-05
Identities = 71/355 (20%), Positives = 143/355 (40%), Gaps = 42/355 (11%)
Query: 131 QRKKLYYDTDYGSKSRGRQSQQEAEEEEREEEEEAQIIQRRLAQALQEDDFGVAWVEAFA 190
Q+++ D G R++ +EAEE + E EA +R++ +A + +A A
Sbjct: 2070 QQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARA 2129
Query: 191 KPVPQVDEAETRVVKDLAKVSVKEKLKMLRKESPELLELIEDLKVKLTEVKDELEPLLEL 250
+ ++ ++ A+ + E+ + +K++ + E+E +
Sbjct: 2130 QAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADA----------------EMEKHKKF 2173
Query: 251 VEQGIIPPGKGSQYLRTKYNLYLNYCSNISFYLILKARRVPAHG-------HPVIERLVT 303
EQ + + Q L T L L + L + +R+ A V E L +
Sbjct: 2174 AEQTLRQKAQVEQELTT-LRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFS 2232
Query: 304 YRNLINKLSVVDQKLSSEIRHLLTLKDDAVKKELIPKAKSTKPKPKSVSKTSAAA----- 358
R + +LS + ++ +E R L+ D ++ L +A+ K + ++ S AA
Sbjct: 2233 VRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAAR 2292
Query: 359 ---CAVTDLSDDSDFDEKAKLKYYKEIEDRQKLKRKKE-----ENSTEEQALEDQNAKRA 410
A DL+ EK + + +++ +LK + E + +EQA Q K
Sbjct: 2293 LRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQ 2352
Query: 411 ITYQIAKNRGLTPRRKKIDRNPRVKHREKFRRAKIR----RRGQVREVRKEEQRY 461
+ Q+A+ R + +R +++ + R K+R R Q R ++ QR+
Sbjct: 2353 MAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQAR-AEEDAQRF 2406
Score = 38.9 bits (89), Expect = 0.010
Identities = 77/409 (18%), Positives = 161/409 (39%), Gaps = 48/409 (11%)
Query: 78 EEEEVLALDMDDEDDE------DGGNAGEEEEEE------NADDDGGSSVQSEAEASVDP 125
+EE V + +E + + A EE E E A++ +Q+E E +
Sbjct: 1597 QEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAE-EVAQQK 1655
Query: 126 SLSWGQRKKLYYDTDYGSKSRGRQSQQEAEEEEREEEEEAQIIQRRLAQALQEDDFGVAW 185
SL+ + +K + + ++ RG+ +Q + E E+E + QR+LA+ + +A
Sbjct: 1656 SLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEK--QRQLAEGTAQQ--RLAA 1711
Query: 186 VEAFAKPVPQVDEAETRVVKDLAKVSVKEKLKMLRKESPELLELIEDLKVKLTEVKDELE 245
+ + + ++ E + + ++E+L L++E+ + ++L+ +L +V+ E+E
Sbjct: 1712 EQELIRLRAETEQGEQQ------RQLLEEELARLQREAAAATQKRQELEAELAKVRAEME 1765
Query: 246 PLL----ELVEQGIIPPGKGSQYLRTKYNLYLNYCSNISFYLIL----KARRVPAHGHPV 297
LL E+ K Q L + + + L K +R A
Sbjct: 1766 VLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAA 1825
Query: 298 IERLVTYRNLINKLSVVDQKLSSEIRHLLTLKDDAVKKELIPKAKSTKPKPKSVSKTSAA 357
+R R L KL+ + + + + LK+ + E + + + + + AA
Sbjct: 1826 RQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAA 1885
Query: 358 --------ACAVTDLSDDSDFDEKAKLKYYKEIEDRQKLKRKKEENSTEEQALEDQNAKR 409
A + DS+ + + L +ED + +R+ EE +A ++ A
Sbjct: 1886 QHKADIEERLAQLRKASDSELERQKGL-----VEDTLRQRRQVEEEILALKASFEKAAAG 1940
Query: 410 AITYQIAKNRGLTPRRKKIDRNPRVKHREKFRRAKIRRRGQVREVRKEE 458
++ R R + R K + + A+ R+ E R+ E
Sbjct: 1941 KAELELELGR----IRSNAEDTLRSKEQAELEAARQRQLAAEEERRRRE 1985
Score = 35.4 bits (80), Expect = 0.12
Identities = 85/445 (19%), Positives = 173/445 (38%), Gaps = 100/445 (22%)
Query: 75 GEEEEEEVLALDMDDEDDEDGGNAGEEEEEENADDDGGSSVQSEAEASVDPSLSWGQRKK 134
G + EEVL + + A E E Q+EA+ +L R +
Sbjct: 1097 GTQGAEEVLRAHEEQLKEAQAVPATLPELEATKASLKKLRAQAEAQQPTFDAL----RDE 1152
Query: 135 LYYDTDYGSKSRGRQSQQEAEEEEREEEEEAQIIQRRLAQALQED--------------- 179
L + G + + R +++ E E R E AQ+++R A Q D
Sbjct: 1153 LRGAQEVGERLQQRHGERDVEVE-RWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLRY 1211
Query: 180 -----DFGVAWVEAFAKPVPQVDE---AETRVVKDLAKVSVK---------EKLKMLRKE 222
D AW++ + Q+ A+++ V++ + EK++ ++
Sbjct: 1212 YRESADPLGAWLQDARRRQEQIQAMPLADSQAVREQLRQEQALLEEIERHGEKVEECQRF 1271
Query: 223 SPELLELIEDLKVKLTEVKDELEPLLELVEQGIIPPGKGS---QY--LRTKYNLYLNYCS 277
+ + + I+D +++L K +LEP+ ++ + G S +Y LRT Y+ S
Sbjct: 1272 AKQYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTS 1331
Query: 278 NISFYLILKARRVPAHGHPVIERLVTYRNLINKLSVVDQKLSSEIRHLLTLKDDAVKKEL 337
++ RR+ +++L+ + R A ++E
Sbjct: 1332 QYIKFISETLRRMEE----------------------EERLAEQQR--------AEERER 1361
Query: 338 IPKAKSTKPKPKSVSKTSAAACAVTDLSDDSDFDEKAKLKYYKEIEDRQKLKRKKEENST 397
+ + ++ K + +++ A A A + + KE++ R ++E
Sbjct: 1362 LAEVEAALEKQRQLAEAHAQAKAQAE-------------REAKELQQRM----QEEVVRR 1404
Query: 398 EEQALEDQNAKRAITYQIAKNRGLTPRRKKIDRNPRVKHREKFRRAKIRRRGQVREVR-- 455
EE A++ Q KR+I ++ + R + + + + + E R+++R ++R VR
Sbjct: 1405 EEAAVDAQQQKRSIQEELQQLR----QSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQ 1460
Query: 456 ---KEEQR--YSGELSGIRAGVKKS 475
E QR GEL +RA +++
Sbjct: 1461 LEATERQRGGAEGELQALRARAEEA 1485
Score = 32.0 bits (71), Expect = 1.3
Identities = 53/204 (25%), Positives = 85/204 (41%), Gaps = 37/204 (18%)
Query: 66 EVQSGDEEDG----EEEEEEVLALDMDDEDDEDGGNAGEEEE---EENADDDGGSSVQSE 118
E Q G ED + EEE+LAL E G E E NA+D S Q+E
Sbjct: 1907 ERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAE 1966
Query: 119 AEASVDPSLSWGQRKKLYYDTDYGSKSRGRQSQQEAEEEEREEEEEAQIIQRRLAQALQE 178
EA+ RQ Q AEEE R E E + +Q+ LA +
Sbjct: 1967 LEAA-------------------------RQRQLAAEEERRRREAEER-VQKSLAAEEEA 2000
Query: 179 DDFGVAWVEAFAKPVPQVDEAETRVVKDLAKVSVKEKLKMLRKESPELLELIEDLKVKLT 238
A +E + +V+EA R +++ A+ +L++ ++ + + L+ E
Sbjct: 2001 ARQRKAALEEVERLKAKVEEA--RRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAV 2058
Query: 239 EVKD-ELEPLLELVEQGIIPPGKG 261
+ K+ EL+ L+ EQ ++ +G
Sbjct: 2059 QQKEQELQQTLQ-QEQSVLDQLRG 2081
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 47.4 bits (111), Expect = 3e-05
Identities = 71/355 (20%), Positives = 143/355 (40%), Gaps = 42/355 (11%)
Query: 131 QRKKLYYDTDYGSKSRGRQSQQEAEEEEREEEEEAQIIQRRLAQALQEDDFGVAWVEAFA 190
Q+++ D G R++ +EAEE + E EA +R++ +A + +A A
Sbjct: 2074 QQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARA 2133
Query: 191 KPVPQVDEAETRVVKDLAKVSVKEKLKMLRKESPELLELIEDLKVKLTEVKDELEPLLEL 250
+ ++ ++ A+ + E+ + +K++ + E+E +
Sbjct: 2134 QAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADA----------------EMEKHKKF 2177
Query: 251 VEQGIIPPGKGSQYLRTKYNLYLNYCSNISFYLILKARRVPAHG-------HPVIERLVT 303
EQ + + Q L T L L + L + +R+ A V E L +
Sbjct: 2178 AEQTLRQKAQVEQELTT-LRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFS 2236
Query: 304 YRNLINKLSVVDQKLSSEIRHLLTLKDDAVKKELIPKAKSTKPKPKSVSKTSAAA----- 358
R + +LS + ++ +E R L+ D ++ L +A+ K + ++ S AA
Sbjct: 2237 VRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAAR 2296
Query: 359 ---CAVTDLSDDSDFDEKAKLKYYKEIEDRQKLKRKKE-----ENSTEEQALEDQNAKRA 410
A DL+ EK + + +++ +LK + E + +EQA Q K
Sbjct: 2297 LRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQ 2356
Query: 411 ITYQIAKNRGLTPRRKKIDRNPRVKHREKFRRAKIR----RRGQVREVRKEEQRY 461
+ Q+A+ R + +R +++ + R K+R R Q R ++ QR+
Sbjct: 2357 MAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQAR-AEEDAQRF 2410
Score = 38.9 bits (89), Expect = 0.010
Identities = 77/409 (18%), Positives = 161/409 (39%), Gaps = 48/409 (11%)
Query: 78 EEEEVLALDMDDEDDE------DGGNAGEEEEEE------NADDDGGSSVQSEAEASVDP 125
+EE V + +E + + A EE E E A++ +Q+E E +
Sbjct: 1601 QEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAE-EVAQQK 1659
Query: 126 SLSWGQRKKLYYDTDYGSKSRGRQSQQEAEEEEREEEEEAQIIQRRLAQALQEDDFGVAW 185
SL+ + +K + + ++ RG+ +Q + E E+E + QR+LA+ + +A
Sbjct: 1660 SLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEK--QRQLAEGTAQQ--RLAA 1715
Query: 186 VEAFAKPVPQVDEAETRVVKDLAKVSVKEKLKMLRKESPELLELIEDLKVKLTEVKDELE 245
+ + + ++ E + + ++E+L L++E+ + ++L+ +L +V+ E+E
Sbjct: 1716 EQELIRLRAETEQGEQQ------RQLLEEELARLQREAAAATQKRQELEAELAKVRAEME 1769
Query: 246 PLL----ELVEQGIIPPGKGSQYLRTKYNLYLNYCSNISFYLIL----KARRVPAHGHPV 297
LL E+ K Q L + + + L K +R A
Sbjct: 1770 VLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAA 1829
Query: 298 IERLVTYRNLINKLSVVDQKLSSEIRHLLTLKDDAVKKELIPKAKSTKPKPKSVSKTSAA 357
+R R L KL+ + + + + LK+ + E + + + + + AA
Sbjct: 1830 RQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAA 1889
Query: 358 --------ACAVTDLSDDSDFDEKAKLKYYKEIEDRQKLKRKKEENSTEEQALEDQNAKR 409
A + DS+ + + L +ED + +R+ EE +A ++ A
Sbjct: 1890 QHKADIEERLAQLRKASDSELERQKGL-----VEDTLRQRRQVEEEILALKASFEKAAAG 1944
Query: 410 AITYQIAKNRGLTPRRKKIDRNPRVKHREKFRRAKIRRRGQVREVRKEE 458
++ R R + R K + + A+ R+ E R+ E
Sbjct: 1945 KAELELELGR----IRSNAEDTLRSKEQAELEAARQRQLAAEEERRRRE 1989
Score = 35.4 bits (80), Expect = 0.12
Identities = 85/445 (19%), Positives = 173/445 (38%), Gaps = 100/445 (22%)
Query: 75 GEEEEEEVLALDMDDEDDEDGGNAGEEEEEENADDDGGSSVQSEAEASVDPSLSWGQRKK 134
G + EEVL + + A E E Q+EA+ +L R +
Sbjct: 1101 GTQGAEEVLRAHEEQLKEAQAVPATLPELEATKASLKKLRAQAEAQQPTFDAL----RDE 1156
Query: 135 LYYDTDYGSKSRGRQSQQEAEEEEREEEEEAQIIQRRLAQALQED--------------- 179
L + G + + R +++ E E R E AQ+++R A Q D
Sbjct: 1157 LRGAQEVGERLQQRHGERDVEVE-RWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLRY 1215
Query: 180 -----DFGVAWVEAFAKPVPQVDE---AETRVVKDLAKVSVK---------EKLKMLRKE 222
D AW++ + Q+ A+++ V++ + EK++ ++
Sbjct: 1216 YRESADPLGAWLQDARRRQEQIQAMPLADSQAVREQLRQEQALLEEIERHGEKVEECQRF 1275
Query: 223 SPELLELIEDLKVKLTEVKDELEPLLELVEQGIIPPGKGS---QY--LRTKYNLYLNYCS 277
+ + + I+D +++L K +LEP+ ++ + G S +Y LRT Y+ S
Sbjct: 1276 AKQYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTS 1335
Query: 278 NISFYLILKARRVPAHGHPVIERLVTYRNLINKLSVVDQKLSSEIRHLLTLKDDAVKKEL 337
++ RR+ +++L+ + R A ++E
Sbjct: 1336 QYIKFISETLRRMEE----------------------EERLAEQQR--------AEERER 1365
Query: 338 IPKAKSTKPKPKSVSKTSAAACAVTDLSDDSDFDEKAKLKYYKEIEDRQKLKRKKEENST 397
+ + ++ K + +++ A A A + + KE++ R ++E
Sbjct: 1366 LAEVEAALEKQRQLAEAHAQAKAQAE-------------REAKELQQRM----QEEVVRR 1408
Query: 398 EEQALEDQNAKRAITYQIAKNRGLTPRRKKIDRNPRVKHREKFRRAKIRRRGQVREVR-- 455
EE A++ Q KR+I ++ + R + + + + + E R+++R ++R VR
Sbjct: 1409 EEAAVDAQQQKRSIQEELQQLR----QSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQ 1464
Query: 456 ---KEEQR--YSGELSGIRAGVKKS 475
E QR GEL +RA +++
Sbjct: 1465 LEATERQRGGAEGELQALRARAEEA 1489
Score = 32.0 bits (71), Expect = 1.3
Identities = 53/204 (25%), Positives = 85/204 (41%), Gaps = 37/204 (18%)
Query: 66 EVQSGDEEDG----EEEEEEVLALDMDDEDDEDGGNAGEEEE---EENADDDGGSSVQSE 118
E Q G ED + EEE+LAL E G E E NA+D S Q+E
Sbjct: 1911 ERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAE 1970
Query: 119 AEASVDPSLSWGQRKKLYYDTDYGSKSRGRQSQQEAEEEEREEEEEAQIIQRRLAQALQE 178
EA+ RQ Q AEEE R E E + +Q+ LA +
Sbjct: 1971 LEAA-------------------------RQRQLAAEEERRRREAEER-VQKSLAAEEEA 2004
Query: 179 DDFGVAWVEAFAKPVPQVDEAETRVVKDLAKVSVKEKLKMLRKESPELLELIEDLKVKLT 238
A +E + +V+EA R +++ A+ +L++ ++ + + L+ E
Sbjct: 2005 ARQRKAALEEVERLKAKVEEA--RRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAV 2062
Query: 239 EVKD-ELEPLLELVEQGIIPPGKG 261
+ K+ EL+ L+ EQ ++ +G
Sbjct: 2063 QQKEQELQQTLQ-QEQSVLDQLRG 2085
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 47.4 bits (111), Expect = 3e-05
Identities = 71/355 (20%), Positives = 143/355 (40%), Gaps = 42/355 (11%)
Query: 131 QRKKLYYDTDYGSKSRGRQSQQEAEEEEREEEEEAQIIQRRLAQALQEDDFGVAWVEAFA 190
Q+++ D G R++ +EAEE + E EA +R++ +A + +A A
Sbjct: 2070 QQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARA 2129
Query: 191 KPVPQVDEAETRVVKDLAKVSVKEKLKMLRKESPELLELIEDLKVKLTEVKDELEPLLEL 250
+ ++ ++ A+ + E+ + +K++ + E+E +
Sbjct: 2130 QAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADA----------------EMEKHKKF 2173
Query: 251 VEQGIIPPGKGSQYLRTKYNLYLNYCSNISFYLILKARRVPAHG-------HPVIERLVT 303
EQ + + Q L T L L + L + +R+ A V E L +
Sbjct: 2174 AEQTLRQKAQVEQELTT-LRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFS 2232
Query: 304 YRNLINKLSVVDQKLSSEIRHLLTLKDDAVKKELIPKAKSTKPKPKSVSKTSAAA----- 358
R + +LS + ++ +E R L+ D ++ L +A+ K + ++ S AA
Sbjct: 2233 VRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAAR 2292
Query: 359 ---CAVTDLSDDSDFDEKAKLKYYKEIEDRQKLKRKKE-----ENSTEEQALEDQNAKRA 410
A DL+ EK + + +++ +LK + E + +EQA Q K
Sbjct: 2293 LRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQ 2352
Query: 411 ITYQIAKNRGLTPRRKKIDRNPRVKHREKFRRAKIR----RRGQVREVRKEEQRY 461
+ Q+A+ R + +R +++ + R K+R R Q R ++ QR+
Sbjct: 2353 MAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQAR-AEEDAQRF 2406
Score = 38.9 bits (89), Expect = 0.010
Identities = 77/409 (18%), Positives = 161/409 (39%), Gaps = 48/409 (11%)
Query: 78 EEEEVLALDMDDEDDE------DGGNAGEEEEEE------NADDDGGSSVQSEAEASVDP 125
+EE V + +E + + A EE E E A++ +Q+E E +
Sbjct: 1597 QEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAE-EVAQQK 1655
Query: 126 SLSWGQRKKLYYDTDYGSKSRGRQSQQEAEEEEREEEEEAQIIQRRLAQALQEDDFGVAW 185
SL+ + +K + + ++ RG+ +Q + E E+E + QR+LA+ + +A
Sbjct: 1656 SLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEK--QRQLAEGTAQQ--RLAA 1711
Query: 186 VEAFAKPVPQVDEAETRVVKDLAKVSVKEKLKMLRKESPELLELIEDLKVKLTEVKDELE 245
+ + + ++ E + + ++E+L L++E+ + ++L+ +L +V+ E+E
Sbjct: 1712 EQELIRLRAETEQGEQQ------RQLLEEELARLQREAAAATQKRQELEAELAKVRAEME 1765
Query: 246 PLL----ELVEQGIIPPGKGSQYLRTKYNLYLNYCSNISFYLIL----KARRVPAHGHPV 297
LL E+ K Q L + + + L K +R A
Sbjct: 1766 VLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAA 1825
Query: 298 IERLVTYRNLINKLSVVDQKLSSEIRHLLTLKDDAVKKELIPKAKSTKPKPKSVSKTSAA 357
+R R L KL+ + + + + LK+ + E + + + + + AA
Sbjct: 1826 RQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAA 1885
Query: 358 --------ACAVTDLSDDSDFDEKAKLKYYKEIEDRQKLKRKKEENSTEEQALEDQNAKR 409
A + DS+ + + L +ED + +R+ EE +A ++ A
Sbjct: 1886 QHKADIEERLAQLRKASDSELERQKGL-----VEDTLRQRRQVEEEILALKASFEKAAAG 1940
Query: 410 AITYQIAKNRGLTPRRKKIDRNPRVKHREKFRRAKIRRRGQVREVRKEE 458
++ R R + R K + + A+ R+ E R+ E
Sbjct: 1941 KAELELELGR----IRSNAEDTLRSKEQAELEAARQRQLAAEEERRRRE 1985
Score = 35.4 bits (80), Expect = 0.12
Identities = 85/445 (19%), Positives = 173/445 (38%), Gaps = 100/445 (22%)
Query: 75 GEEEEEEVLALDMDDEDDEDGGNAGEEEEEENADDDGGSSVQSEAEASVDPSLSWGQRKK 134
G + EEVL + + A E E Q+EA+ +L R +
Sbjct: 1097 GTQGAEEVLRAHEEQLKEAQAVPATLPELEATKASLKKLRAQAEAQQPTFDAL----RDE 1152
Query: 135 LYYDTDYGSKSRGRQSQQEAEEEEREEEEEAQIIQRRLAQALQED--------------- 179
L + G + + R +++ E E R E AQ+++R A Q D
Sbjct: 1153 LRGAQEVGERLQQRHGERDVEVE-RWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLRY 1211
Query: 180 -----DFGVAWVEAFAKPVPQVDE---AETRVVKDLAKVSVK---------EKLKMLRKE 222
D AW++ + Q+ A+++ V++ + EK++ ++
Sbjct: 1212 YRESADPLGAWLQDARRRQEQIQAMPLADSQAVREQLRQEQALLEEIERHGEKVEECQRF 1271
Query: 223 SPELLELIEDLKVKLTEVKDELEPLLELVEQGIIPPGKGS---QY--LRTKYNLYLNYCS 277
+ + + I+D +++L K +LEP+ ++ + G S +Y LRT Y+ S
Sbjct: 1272 AKQYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTS 1331
Query: 278 NISFYLILKARRVPAHGHPVIERLVTYRNLINKLSVVDQKLSSEIRHLLTLKDDAVKKEL 337
++ RR+ +++L+ + R A ++E
Sbjct: 1332 QYIKFISETLRRMEE----------------------EERLAEQQR--------AEERER 1361
Query: 338 IPKAKSTKPKPKSVSKTSAAACAVTDLSDDSDFDEKAKLKYYKEIEDRQKLKRKKEENST 397
+ + ++ K + +++ A A A + + KE++ R ++E
Sbjct: 1362 LAEVEAALEKQRQLAEAHAQAKAQAE-------------REAKELQQRM----QEEVVRR 1404
Query: 398 EEQALEDQNAKRAITYQIAKNRGLTPRRKKIDRNPRVKHREKFRRAKIRRRGQVREVR-- 455
EE A++ Q KR+I ++ + R + + + + + E R+++R ++R VR
Sbjct: 1405 EEAAVDAQQQKRSIQEELQQLR----QSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQ 1460
Query: 456 ---KEEQR--YSGELSGIRAGVKKS 475
E QR GEL +RA +++
Sbjct: 1461 LEATERQRGGAEGELQALRARAEEA 1485
Score = 32.0 bits (71), Expect = 1.3
Identities = 53/204 (25%), Positives = 85/204 (41%), Gaps = 37/204 (18%)
Query: 66 EVQSGDEEDG----EEEEEEVLALDMDDEDDEDGGNAGEEEE---EENADDDGGSSVQSE 118
E Q G ED + EEE+LAL E G E E NA+D S Q+E
Sbjct: 1907 ERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAE 1966
Query: 119 AEASVDPSLSWGQRKKLYYDTDYGSKSRGRQSQQEAEEEEREEEEEAQIIQRRLAQALQE 178
EA+ RQ Q AEEE R E E + +Q+ LA +
Sbjct: 1967 LEAA-------------------------RQRQLAAEEERRRREAEER-VQKSLAAEEEA 2000
Query: 179 DDFGVAWVEAFAKPVPQVDEAETRVVKDLAKVSVKEKLKMLRKESPELLELIEDLKVKLT 238
A +E + +V+EA R +++ A+ +L++ ++ + + L+ E
Sbjct: 2001 ARQRKAALEEVERLKAKVEEA--RRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAV 2058
Query: 239 EVKD-ELEPLLELVEQGIIPPGKG 261
+ K+ EL+ L+ EQ ++ +G
Sbjct: 2059 QQKEQELQQTLQ-QEQSVLDQLRG 2081
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.129 0.350
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,200,298
Number of Sequences: 37866
Number of extensions: 997799
Number of successful extensions: 23498
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 393
Number of HSP's successfully gapped in prelim test: 709
Number of HSP's that attempted gapping in prelim test: 9491
Number of HSP's gapped (non-prelim): 7534
length of query: 479
length of database: 18,247,518
effective HSP length: 106
effective length of query: 373
effective length of database: 14,233,722
effective search space: 5309178306
effective search space used: 5309178306
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.