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Search of human proteins with 9966781
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|9966781 claudin 2 [Homo sapiens]
(230 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|9966781 claudin 2 [Homo sapiens] 456 e-129
gi|225703142 claudin 14 [Homo sapiens] 222 2e-58
gi|21536294 claudin 14 [Homo sapiens] 222 2e-58
gi|225703138 claudin 14 [Homo sapiens] 222 2e-58
gi|6912314 claudin 14 [Homo sapiens] 222 2e-58
gi|225703140 claudin 14 [Homo sapiens] 222 2e-58
gi|4502875 claudin 3 [Homo sapiens] 177 9e-45
gi|11141861 claudin 9 [Homo sapiens] 174 6e-44
gi|4502877 claudin 4 [Homo sapiens] 173 1e-43
gi|153792768 claudin 6 [Homo sapiens] 172 2e-43
gi|183979973 claudin 19 isoform a [Homo sapiens] 171 6e-43
gi|183979975 claudin 19 isoform b [Homo sapiens] 168 4e-42
gi|153792186 claudin 7 [Homo sapiens] 167 7e-42
gi|10863887 claudin 1 [Homo sapiens] 157 7e-39
gi|47716519 claudin 20 [Homo sapiens] 154 6e-38
gi|195947374 claudin 5 [Homo sapiens] 149 1e-36
gi|195947372 claudin 5 [Homo sapiens] 149 1e-36
gi|6912316 claudin 17 [Homo sapiens] 147 6e-36
gi|40788011 claudin 8 [Homo sapiens] 146 2e-35
gi|7656981 claudin 15 [Homo sapiens] 123 2e-28
gi|5921465 claudin 10 isoform b [Homo sapiens] 114 9e-26
gi|50345279 claudin 18 isoform 2 [Homo sapiens] 104 6e-23
gi|33598916 claudin 10 isoform a [Homo sapiens] 103 1e-22
gi|7705961 claudin 18 isoform 1 [Homo sapiens] 102 2e-22
gi|169166402 PREDICTED: claudin-24-like [Homo sapiens] 102 4e-22
gi|169167239 PREDICTED: claudin-24-like [Homo sapiens] 100 1e-21
gi|169166931 PREDICTED: claudin-24-like [Homo sapiens] 100 1e-21
gi|162417973 claudin 22 [Homo sapiens] 99 4e-21
gi|157820127 claudin-like [Homo sapiens] 92 4e-19
gi|231569235 claudin 10 isoform a_i1 [Homo sapiens] 89 2e-18
>gi|9966781 claudin 2 [Homo sapiens]
Length = 230
Score = 456 bits (1174), Expect = e-129
Identities = 230/230 (100%), Positives = 230/230 (100%)
Query: 1 MASLGLQLVGYILGLLGLLGTLVAMLLPSWKTSSYVGASIVTAVGFSKGLWMECATHSTG 60
MASLGLQLVGYILGLLGLLGTLVAMLLPSWKTSSYVGASIVTAVGFSKGLWMECATHSTG
Sbjct: 1 MASLGLQLVGYILGLLGLLGTLVAMLLPSWKTSSYVGASIVTAVGFSKGLWMECATHSTG 60
Query: 61 ITQCDIYSTLLGLPADIQAAQAMMVTSSAISSLACIISVVGMRCTVFCQESRAKDRVAVA 120
ITQCDIYSTLLGLPADIQAAQAMMVTSSAISSLACIISVVGMRCTVFCQESRAKDRVAVA
Sbjct: 61 ITQCDIYSTLLGLPADIQAAQAMMVTSSAISSLACIISVVGMRCTVFCQESRAKDRVAVA 120
Query: 121 GGVFFILGGLLGFIPVAWNLHGILRDFYSPLVPDSMKFEIGEALYLGIISSLFSLIAGII 180
GGVFFILGGLLGFIPVAWNLHGILRDFYSPLVPDSMKFEIGEALYLGIISSLFSLIAGII
Sbjct: 121 GGVFFILGGLLGFIPVAWNLHGILRDFYSPLVPDSMKFEIGEALYLGIISSLFSLIAGII 180
Query: 181 LCFSCSSQRNRSNYYDAYQAQPLATRSSPRPGQPPKVKSEFNSYSLTGYV 230
LCFSCSSQRNRSNYYDAYQAQPLATRSSPRPGQPPKVKSEFNSYSLTGYV
Sbjct: 181 LCFSCSSQRNRSNYYDAYQAQPLATRSSPRPGQPPKVKSEFNSYSLTGYV 230
>gi|225703142 claudin 14 [Homo sapiens]
Length = 239
Score = 222 bits (565), Expect = 2e-58
Identities = 109/230 (47%), Positives = 153/230 (66%), Gaps = 7/230 (3%)
Query: 1 MASLGLQLVGYILGLLGLLGTLVAMLLPSWKTSSYVGASIVTAVGFSKGLWMECATHSTG 60
MAS +QL+G++L LG++GTL+ +LP W+ +++VG +I+TAV + KGLWMEC HSTG
Sbjct: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
Query: 61 ITQCDIYSTLLGLPADIQAAQAMMVTSSAISSLACIISVVGMRCTVFCQESRAKDRVAVA 120
I QC IY +LL LP D+QAA+A+MV S +S +AC +V+GM+CT + + AK A+
Sbjct: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAIL 120
Query: 121 GGVFFILGGLLGFIPVAWNLHGILRDFYSPLVPDSMKFEIGEALYLGIISSLFSLIAGII 180
GG FIL GLL + V+W + ++++FY+PL+P MKFEIG+ALYLG ISS SLI G +
Sbjct: 121 GGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTL 180
Query: 181 LCFSCSSQRNRSNYYDAYQAQPLATRSSPRPG---QPPKVKSEFNSYSLT 227
LC SC + Y YQA P AT ++ QPP + + S+T
Sbjct: 181 LCLSCQDEAP----YRPYQAPPRATTTTANTAPAYQPPAAYKDNRAPSVT 226
>gi|21536294 claudin 14 [Homo sapiens]
Length = 239
Score = 222 bits (565), Expect = 2e-58
Identities = 109/230 (47%), Positives = 153/230 (66%), Gaps = 7/230 (3%)
Query: 1 MASLGLQLVGYILGLLGLLGTLVAMLLPSWKTSSYVGASIVTAVGFSKGLWMECATHSTG 60
MAS +QL+G++L LG++GTL+ +LP W+ +++VG +I+TAV + KGLWMEC HSTG
Sbjct: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
Query: 61 ITQCDIYSTLLGLPADIQAAQAMMVTSSAISSLACIISVVGMRCTVFCQESRAKDRVAVA 120
I QC IY +LL LP D+QAA+A+MV S +S +AC +V+GM+CT + + AK A+
Sbjct: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAIL 120
Query: 121 GGVFFILGGLLGFIPVAWNLHGILRDFYSPLVPDSMKFEIGEALYLGIISSLFSLIAGII 180
GG FIL GLL + V+W + ++++FY+PL+P MKFEIG+ALYLG ISS SLI G +
Sbjct: 121 GGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTL 180
Query: 181 LCFSCSSQRNRSNYYDAYQAQPLATRSSPRPG---QPPKVKSEFNSYSLT 227
LC SC + Y YQA P AT ++ QPP + + S+T
Sbjct: 181 LCLSCQDEAP----YRPYQAPPRATTTTANTAPAYQPPAAYKDNRAPSVT 226
>gi|225703138 claudin 14 [Homo sapiens]
Length = 239
Score = 222 bits (565), Expect = 2e-58
Identities = 109/230 (47%), Positives = 153/230 (66%), Gaps = 7/230 (3%)
Query: 1 MASLGLQLVGYILGLLGLLGTLVAMLLPSWKTSSYVGASIVTAVGFSKGLWMECATHSTG 60
MAS +QL+G++L LG++GTL+ +LP W+ +++VG +I+TAV + KGLWMEC HSTG
Sbjct: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
Query: 61 ITQCDIYSTLLGLPADIQAAQAMMVTSSAISSLACIISVVGMRCTVFCQESRAKDRVAVA 120
I QC IY +LL LP D+QAA+A+MV S +S +AC +V+GM+CT + + AK A+
Sbjct: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAIL 120
Query: 121 GGVFFILGGLLGFIPVAWNLHGILRDFYSPLVPDSMKFEIGEALYLGIISSLFSLIAGII 180
GG FIL GLL + V+W + ++++FY+PL+P MKFEIG+ALYLG ISS SLI G +
Sbjct: 121 GGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTL 180
Query: 181 LCFSCSSQRNRSNYYDAYQAQPLATRSSPRPG---QPPKVKSEFNSYSLT 227
LC SC + Y YQA P AT ++ QPP + + S+T
Sbjct: 181 LCLSCQDEAP----YRPYQAPPRATTTTANTAPAYQPPAAYKDNRAPSVT 226
>gi|6912314 claudin 14 [Homo sapiens]
Length = 239
Score = 222 bits (565), Expect = 2e-58
Identities = 109/230 (47%), Positives = 153/230 (66%), Gaps = 7/230 (3%)
Query: 1 MASLGLQLVGYILGLLGLLGTLVAMLLPSWKTSSYVGASIVTAVGFSKGLWMECATHSTG 60
MAS +QL+G++L LG++GTL+ +LP W+ +++VG +I+TAV + KGLWMEC HSTG
Sbjct: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
Query: 61 ITQCDIYSTLLGLPADIQAAQAMMVTSSAISSLACIISVVGMRCTVFCQESRAKDRVAVA 120
I QC IY +LL LP D+QAA+A+MV S +S +AC +V+GM+CT + + AK A+
Sbjct: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAIL 120
Query: 121 GGVFFILGGLLGFIPVAWNLHGILRDFYSPLVPDSMKFEIGEALYLGIISSLFSLIAGII 180
GG FIL GLL + V+W + ++++FY+PL+P MKFEIG+ALYLG ISS SLI G +
Sbjct: 121 GGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTL 180
Query: 181 LCFSCSSQRNRSNYYDAYQAQPLATRSSPRPG---QPPKVKSEFNSYSLT 227
LC SC + Y YQA P AT ++ QPP + + S+T
Sbjct: 181 LCLSCQDEAP----YRPYQAPPRATTTTANTAPAYQPPAAYKDNRAPSVT 226
>gi|225703140 claudin 14 [Homo sapiens]
Length = 239
Score = 222 bits (565), Expect = 2e-58
Identities = 109/230 (47%), Positives = 153/230 (66%), Gaps = 7/230 (3%)
Query: 1 MASLGLQLVGYILGLLGLLGTLVAMLLPSWKTSSYVGASIVTAVGFSKGLWMECATHSTG 60
MAS +QL+G++L LG++GTL+ +LP W+ +++VG +I+TAV + KGLWMEC HSTG
Sbjct: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
Query: 61 ITQCDIYSTLLGLPADIQAAQAMMVTSSAISSLACIISVVGMRCTVFCQESRAKDRVAVA 120
I QC IY +LL LP D+QAA+A+MV S +S +AC +V+GM+CT + + AK A+
Sbjct: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAIL 120
Query: 121 GGVFFILGGLLGFIPVAWNLHGILRDFYSPLVPDSMKFEIGEALYLGIISSLFSLIAGII 180
GG FIL GLL + V+W + ++++FY+PL+P MKFEIG+ALYLG ISS SLI G +
Sbjct: 121 GGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTL 180
Query: 181 LCFSCSSQRNRSNYYDAYQAQPLATRSSPRPG---QPPKVKSEFNSYSLT 227
LC SC + Y YQA P AT ++ QPP + + S+T
Sbjct: 181 LCLSCQDEAP----YRPYQAPPRATTTTANTAPAYQPPAAYKDNRAPSVT 226
>gi|4502875 claudin 3 [Homo sapiens]
Length = 220
Score = 177 bits (448), Expect = 9e-45
Identities = 77/203 (37%), Positives = 130/203 (64%)
Query: 3 SLGLQLVGYILGLLGLLGTLVAMLLPSWKTSSYVGASIVTAVGFSKGLWMECATHSTGIT 62
S+GL++ G L +LG LGT+V LP W+ S+++G++I+T+ +GLWM C STG
Sbjct: 2 SMGLEITGTALAVLGWLGTIVCCALPMWRVSAFIGSNIITSQNIWEGLWMNCVVQSTGQM 61
Query: 63 QCDIYSTLLGLPADIQAAQAMMVTSSAISSLACIISVVGMRCTVFCQESRAKDRVAVAGG 122
QC +Y +LL LP D+QAA+A++V + +++ ++++VG +CT Q+ AK ++ + G
Sbjct: 62 QCKVYDSLLALPQDLQAARALIVVAILLAAFGLLVALVGAQCTNCVQDDTAKAKITIVAG 121
Query: 123 VFFILGGLLGFIPVAWNLHGILRDFYSPLVPDSMKFEIGEALYLGIISSLFSLIAGIILC 182
V F+L LL +PV+W+ + I+RDFY+P+VP++ K E+G LY+G ++ L+ G +LC
Sbjct: 122 VLFLLAALLTLVPVSWSANTIIRDFYNPVVPEAQKREMGAGLYVGWAAAALQLLGGALLC 181
Query: 183 FSCSSQRNRSNYYDAYQAQPLAT 205
SC + + + P +T
Sbjct: 182 CSCPPREKKYTATKVVYSAPRST 204
>gi|11141861 claudin 9 [Homo sapiens]
Length = 217
Score = 174 bits (441), Expect = 6e-44
Identities = 80/185 (43%), Positives = 122/185 (65%)
Query: 1 MASLGLQLVGYILGLLGLLGTLVAMLLPSWKTSSYVGASIVTAVGFSKGLWMECATHSTG 60
MAS GL+L+G L +LG LGTLV+ LP WK ++++G SIV A +GLWM C STG
Sbjct: 1 MASTGLELLGMTLAVLGWLGTLVSCALPLWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60
Query: 61 ITQCDIYSTLLGLPADIQAAQAMMVTSSAISSLACIISVVGMRCTVFCQESRAKDRVAVA 120
QC +Y +LL LP D+QAA+A+ V + ++ L ++++ G +CT ++ AK R+ +
Sbjct: 61 QMQCKVYDSLLALPQDLQAARALCVIALLLALLGLLVAITGAQCTTCVEDEGAKARIVLT 120
Query: 121 GGVFFILGGLLGFIPVAWNLHGILRDFYSPLVPDSMKFEIGEALYLGIISSLFSLIAGII 180
GV +L G+L IPV W H I++DFY+PLV +++K E+G +LYLG ++ ++ G +
Sbjct: 121 AGVILLLAGILVLIPVCWTAHAIIQDFYNPLVAEALKRELGASLYLGWAAAALLMLGGGL 180
Query: 181 LCFSC 185
LC +C
Sbjct: 181 LCCTC 185
>gi|4502877 claudin 4 [Homo sapiens]
Length = 209
Score = 173 bits (439), Expect = 1e-43
Identities = 82/208 (39%), Positives = 133/208 (63%), Gaps = 5/208 (2%)
Query: 1 MASLGLQLVGYILGLLGLLGTLVAMLLPSWKTSSYVGASIVTAVGFSKGLWMECATHSTG 60
MAS+GLQ++G L +LG L ++ LP W+ ++++G++IVT+ +GLWM C STG
Sbjct: 1 MASMGLQVMGIALAVLGWLAVMLCCALPMWRVTAFIGSNIVTSQTIWEGLWMNCVVQSTG 60
Query: 61 ITQCDIYSTLLGLPADIQAAQAMMVTSSAISSLACIISVVGMRCTVFCQESRAKDRVAVA 120
QC +Y +LL LP D+QAA+A+++ S +++L ++SVVG +CT ++ AK + +
Sbjct: 61 QMQCKVYDSLLALPQDLQAARALVIISIIVAALGVLLSVVGGKCTNCLEDESAKAKTMIV 120
Query: 121 GGVFFILGGLLGFIPVAWNLHGILRDFYSPLVPDSMKFEIGEALYLGIISSLFSLIAGII 180
GV F+L GL+ +PV+W H I++DFY+PLV K E+G +LY+G +S L+ G +
Sbjct: 121 AGVVFLLAGLMVIVPVSWTAHNIIQDFYNPLVASGQKREMGASLYVGWAASGLLLLGGGL 180
Query: 181 LCFSCSSQRNRSNYYDAYQAQPLATRSS 208
LC +C + ++ Y A+ A RS+
Sbjct: 181 LCCNCPPRTDK-----PYSAKYSAARSA 203
>gi|153792768 claudin 6 [Homo sapiens]
Length = 220
Score = 172 bits (436), Expect = 2e-43
Identities = 84/211 (39%), Positives = 127/211 (60%), Gaps = 2/211 (0%)
Query: 1 MASLGLQLVGYILGLLGLLGTLVAMLLPSWKTSSYVGASIVTAVGFSKGLWMECATHSTG 60
MAS G+Q++G +L LLG + LV+ LP WK ++++G SIV A +GLWM C STG
Sbjct: 1 MASAGMQILGVVLTLLGWVNGLVSCALPMWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60
Query: 61 ITQCDIYSTLLGLPADIQAAQAMMVTSSAISSLACIISVVGMRCTVFCQESRAKDRVAVA 120
QC +Y +LL LP D+QAA+A+ V + ++ ++ + G +CT +E +K R+ +
Sbjct: 61 QMQCKVYDSLLALPQDLQAARALCVIALLVALFGLLVYLAGAKCTTCVEEKDSKARLVLT 120
Query: 121 GGVFFILGGLLGFIPVAWNLHGILRDFYSPLVPDSMKFEIGEALYLGIISSLFSLIAGII 180
G+ F++ G+L IPV W H I+RDFY+PLV ++ K E+G +LYLG +S L+ G +
Sbjct: 121 SGIVFVISGVLTLIPVCWTAHAIIRDFYNPLVAEAQKRELGASLYLGWAASGLLLLGGGL 180
Query: 181 LCFSCSS--QRNRSNYYDAYQAQPLATRSSP 209
LC +C S + S+Y Y A P
Sbjct: 181 LCCTCPSGGSQGPSHYMARYSTSAPAISRGP 211
>gi|183979973 claudin 19 isoform a [Homo sapiens]
Length = 224
Score = 171 bits (432), Expect = 6e-43
Identities = 89/219 (40%), Positives = 129/219 (58%), Gaps = 1/219 (0%)
Query: 1 MASLGLQLVGYILGLLGLLGTLVAMLLPSWKTSSYVGASIVTAVGFSKGLWMECATHSTG 60
MA+ GLQL+GY L L G +G + + LP WK SSY G +I+TAVG +GLWM CA+ STG
Sbjct: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60
Query: 61 ITQCDIYSTLLGLPADIQAAQAMMVTSSAISSLACIISVVGMRCT-VFCQESRAKDRVAV 119
QC +Y +LL L IQ+A+A+MV + + +A ++SVVGM+CT V AK RVA+
Sbjct: 61 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120
Query: 120 AGGVFFILGGLLGFIPVAWNLHGILRDFYSPLVPDSMKFEIGEALYLGIISSLFSLIAGI 179
AGG FIL GL V+W + ++F++P P + ++E G AL++G S+ +++ G
Sbjct: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS 180
Query: 180 ILCFSCSSQRNRSNYYDAYQAQPLATRSSPRPGQPPKVK 218
LC +C ++ Y+ P A P P K
Sbjct: 181 FLCCTCPEPERPNSSPQPYRPGPSAAAREPVVKLPASAK 219
>gi|183979975 claudin 19 isoform b [Homo sapiens]
Length = 211
Score = 168 bits (425), Expect = 4e-42
Identities = 86/205 (41%), Positives = 126/205 (61%), Gaps = 1/205 (0%)
Query: 1 MASLGLQLVGYILGLLGLLGTLVAMLLPSWKTSSYVGASIVTAVGFSKGLWMECATHSTG 60
MA+ GLQL+GY L L G +G + + LP WK SSY G +I+TAVG +GLWM CA+ STG
Sbjct: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60
Query: 61 ITQCDIYSTLLGLPADIQAAQAMMVTSSAISSLACIISVVGMRCT-VFCQESRAKDRVAV 119
QC +Y +LL L IQ+A+A+MV + + +A ++SVVGM+CT V AK RVA+
Sbjct: 61 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120
Query: 120 AGGVFFILGGLLGFIPVAWNLHGILRDFYSPLVPDSMKFEIGEALYLGIISSLFSLIAGI 179
AGG FIL GL V+W + ++F++P P + ++E G AL++G S+ +++ G
Sbjct: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS 180
Query: 180 ILCFSCSSQRNRSNYYDAYQAQPLA 204
LC +C ++ Y+ P A
Sbjct: 181 FLCCTCPEPERPNSSPQPYRPGPSA 205
>gi|153792186 claudin 7 [Homo sapiens]
Length = 211
Score = 167 bits (423), Expect = 7e-42
Identities = 76/195 (38%), Positives = 122/195 (62%), Gaps = 1/195 (0%)
Query: 1 MASLGLQLVGYILGLLGLLGTLVAMLLPSWKTSSYVGASIVTAVGFSKGLWMECATHSTG 60
MA+ GLQL+G+ + LLG +G + +P W+ SSY G +I+TA KGLWM+C T STG
Sbjct: 1 MANSGLQLLGFSMALLGWVGLVACTAIPQWQMSSYAGDNIITAQAMYKGLWMDCVTQSTG 60
Query: 61 ITQCDIYSTLLGLPADIQAAQAMMVTSSAISSLACIISVVGMRCTVFCQESRAKD-RVAV 119
+ C +Y ++L L A +QA +A+MV S + LA ++ +GM+CT + + K R+A+
Sbjct: 61 MMSCKMYDSVLALSAALQATRALMVVSLVLGFLAMFVATMGMKCTRCGGDDKVKKARIAM 120
Query: 120 AGGVFFILGGLLGFIPVAWNLHGILRDFYSPLVPDSMKFEIGEALYLGIISSLFSLIAGI 179
GG+ FI+ GL + +W H I+ DFY+PL+P ++K+E G A+++G S ++ G
Sbjct: 121 GGGIIFIVAGLAALVACSWYGHQIVTDFYNPLIPTNIKYEFGPAIFIGWAGSALVILGGA 180
Query: 180 ILCFSCSSQRNRSNY 194
+L SC +++ Y
Sbjct: 181 LLSCSCPGNESKAGY 195
>gi|10863887 claudin 1 [Homo sapiens]
Length = 211
Score = 157 bits (397), Expect = 7e-39
Identities = 81/217 (37%), Positives = 122/217 (56%), Gaps = 17/217 (7%)
Query: 1 MASLGLQLVGYILGLLGLLGTLVAMLLPSWKTSSYVGASIVTAVGFSKGLWMECATHSTG 60
MA+ GLQL+G+IL LG +G +V+ LP W+ SY G +IVTA +GLWM C + STG
Sbjct: 1 MANAGLQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTG 60
Query: 61 ITQCDIYSTLLGLPADIQAAQAMMVTSSAISSLACIISVVGMRCTVFCQESRA-KDRVAV 119
QC ++ +LL L + +QA +A+MV + +A ++ VGM+C ++ K R+AV
Sbjct: 61 QIQCKVFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAV 120
Query: 120 AGGVFFILGGLLGFIPVAWNLHGILRDFYSPLVPDSMKFEIGEALYLGIISSLFSLIAGI 179
GG F+L GL + AW + I+++FY P+ P + ++E G+AL+ G ++ L+ G
Sbjct: 121 IGGAIFLLAGLAILVATAWYGNRIVQEFYDPMTPVNARYEFGQALFTGWAAASLCLLGGA 180
Query: 180 ILCFSCSSQRNRSNYYDAYQAQPLATRSSPRPGQPPK 216
+LC SC P T S P P PK
Sbjct: 181 LLCCSC----------------PRKTTSYPTPRPYPK 201
>gi|47716519 claudin 20 [Homo sapiens]
Length = 219
Score = 154 bits (389), Expect = 6e-38
Identities = 82/204 (40%), Positives = 119/204 (58%), Gaps = 1/204 (0%)
Query: 1 MASLGLQLVGYILGLLGLLGTLVAMLLPSWKTSSYVGASIVTAVGFSKGLWMECATHSTG 60
MAS GLQL+ +IL L G+ G L A LLP+WK + V ++I+TA+ GLWM+C +STG
Sbjct: 1 MASAGLQLLAFILALSGVSGVLTATLLPNWKVNVDVDSNIITAIVQLHGLWMDCTWYSTG 60
Query: 61 ITQCDIYSTLLGLPADIQAAQAMMVTSSAISSLACIISVVGMRCTVFCQESRAKDRVAVA 120
+ C + ++L LP +QAA+A MV + +S+L S VGM+CT + K + A
Sbjct: 61 MFSCALKHSILSLPIHVQAARATMVLACVLSALGICTSTVGMKCTRLGGDRETKSHASFA 120
Query: 121 GGVFFILGGLLGFIPVAWNLHGILRDFYSPLVPDSMKFEIGEALYLGIISSLFSLIAGII 180
GGV F+ G+ I W I+ +F VP+S K E G A+Y+G IS++ I+G+I
Sbjct: 121 GGVCFMSAGISSLISTVWYTKEIIANFLDLTVPESNKHEPGGAIYIGFISAMLLFISGMI 180
Query: 181 LCFSCSSQRNRSNYYDAYQAQPLA 204
C SC +RN D QP++
Sbjct: 181 FCTSC-IKRNPEARLDPPTQQPIS 203
>gi|195947374 claudin 5 [Homo sapiens]
Length = 303
Score = 149 bits (377), Expect = 1e-36
Identities = 69/182 (37%), Positives = 115/182 (63%)
Query: 1 MASLGLQLVGYILGLLGLLGTLVAMLLPSWKTSSYVGASIVTAVGFSKGLWMECATHSTG 60
M S L+++G +L L+G G ++A LP W+ ++++ +IVTA KGLWM C STG
Sbjct: 86 MGSAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTG 145
Query: 61 ITQCDIYSTLLGLPADIQAAQAMMVTSSAISSLACIISVVGMRCTVFCQESRAKDRVAVA 120
QC +Y ++L L ++QAA+A+ V++ ++ +A +++ G +CT AK RVA+
Sbjct: 146 HMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGPAKARVALT 205
Query: 121 GGVFFILGGLLGFIPVAWNLHGILRDFYSPLVPDSMKFEIGEALYLGIISSLFSLIAGII 180
GGV ++ GLL +P+ W + ++R+FY P VP S K+E+G ALY+G ++ ++ G +
Sbjct: 206 GGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGCL 265
Query: 181 LC 182
LC
Sbjct: 266 LC 267
>gi|195947372 claudin 5 [Homo sapiens]
Length = 303
Score = 149 bits (377), Expect = 1e-36
Identities = 69/182 (37%), Positives = 115/182 (63%)
Query: 1 MASLGLQLVGYILGLLGLLGTLVAMLLPSWKTSSYVGASIVTAVGFSKGLWMECATHSTG 60
M S L+++G +L L+G G ++A LP W+ ++++ +IVTA KGLWM C STG
Sbjct: 86 MGSAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTG 145
Query: 61 ITQCDIYSTLLGLPADIQAAQAMMVTSSAISSLACIISVVGMRCTVFCQESRAKDRVAVA 120
QC +Y ++L L ++QAA+A+ V++ ++ +A +++ G +CT AK RVA+
Sbjct: 146 HMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGPAKARVALT 205
Query: 121 GGVFFILGGLLGFIPVAWNLHGILRDFYSPLVPDSMKFEIGEALYLGIISSLFSLIAGII 180
GGV ++ GLL +P+ W + ++R+FY P VP S K+E+G ALY+G ++ ++ G +
Sbjct: 206 GGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGCL 265
Query: 181 LC 182
LC
Sbjct: 266 LC 267
>gi|6912316 claudin 17 [Homo sapiens]
Length = 224
Score = 147 bits (372), Expect = 6e-36
Identities = 79/196 (40%), Positives = 114/196 (58%), Gaps = 3/196 (1%)
Query: 1 MASLGLQLVGYILGLLGLLGTLVAMLLPSWKTSSYVGASIVTAVGFSKGLWMECATHSTG 60
MA LQ+ G +LG LG++GTL LLP W+ S++VG++I+ +GLWM C +
Sbjct: 1 MAFYPLQIAGLVLGFLGMVGTLATTLLPQWRVSAFVGSNIIVFERLWEGLWMNCIRQARV 60
Query: 61 ITQCDIYSTLLGLPADIQAAQAMMVTSSAISSLACIISVVGMRCTVFCQES--RAKDRVA 118
QC YS+LL LP ++ A+A+M + A+S +A +I + GM+ V C S RAK +
Sbjct: 61 RLQCKFYSSLLALPPALETARALMCVAVALSLIALLIGICGMK-QVQCTGSNERAKAYLL 119
Query: 119 VAGGVFFILGGLLGFIPVAWNLHGILRDFYSPLVPDSMKFEIGEALYLGIISSLFSLIAG 178
GV FIL G+ IPV+W + I+RDFY+P + K E+G AL+LG S+ I G
Sbjct: 120 GTSGVLFILTGIFVLIPVSWTANIIIRDFYNPAIHIGQKRELGAALFLGWASAAVLFIGG 179
Query: 179 IILCFSCSSQRNRSNY 194
+LC C R + Y
Sbjct: 180 GLLCGFCCCNRKKQGY 195
>gi|40788011 claudin 8 [Homo sapiens]
Length = 225
Score = 146 bits (368), Expect = 2e-35
Identities = 70/197 (35%), Positives = 122/197 (61%), Gaps = 3/197 (1%)
Query: 1 MASLGLQLVGYILGLLGLLGTLVAMLLPSWKTSSYVGASIVTAVGFSKGLWMECATHSTG 60
MA+ L++ G LG +G++GT+ ++P W+ S+++ +IV F +GLWM C +
Sbjct: 1 MATHALEIAGLFLGGVGMVGTVAVTVMPQWRVSAFIENNIVVFENFWEGLWMNCVRQANI 60
Query: 61 ITQCDIYSTLLGLPADIQAAQAMMVTSSAISSLACIISVVGMRCTVFCQES-RAKDRVAV 119
QC IY +LL L D+QAA+ +M +S +S LA +++++GM+CT ++ + K + +
Sbjct: 61 RMQCKIYDSLLALSPDLQAARGLMCAASVMSFLAFMMAILGMKCTRCTGDNEKVKAHILL 120
Query: 120 AGGVFFILGGLLGFIPVAWNLHGILRDFYSPLVPDSMKFEIGEALYLGIISSLFSLIAGI 179
G+ FI+ G++ IPV+W + I+RDFY+ +V + K E+GEALYLG ++L ++ G
Sbjct: 121 TAGIIFIITGMVVLIPVSWVANAIIRDFYNSIVNVAQKRELGEALYLGWTTALVLIVGGA 180
Query: 180 ILC--FSCSSQRNRSNY 194
+ C F C+ + + Y
Sbjct: 181 LFCCVFCCNEKSSSYRY 197
>gi|7656981 claudin 15 [Homo sapiens]
Length = 228
Score = 123 bits (308), Expect = 2e-28
Identities = 71/229 (31%), Positives = 113/229 (49%), Gaps = 3/229 (1%)
Query: 3 SLGLQLVGYILGLLGLLGTLVAMLLPSWKTSSYVGASIVTAVGFSKGLWMECATHSTGIT 62
S+ ++ G+ + +GLL V + W+ S+ G I T F + LW CAT S G+
Sbjct: 2 SMAVETFGFFMATVGLLMLGVTLPNSYWRVSTVHGNVITTNTIF-ENLWFSCATDSLGVY 60
Query: 63 QCDIYSTLLGLPADIQAAQAMMVTSSAISSLACIISVVGMRCT-VFCQESRAKDRVAVAG 121
C + ++L L IQA +A+M+T+ + L ++ + G+RCT + E K ++A
Sbjct: 61 NCWEFPSMLALSGYIQACRALMITAILLGFLGLLLGIAGLRCTNIGGLELSRKAKLAATA 120
Query: 122 GVFFILGGLLGFIPVAWNLHGILRDFYSPLVPDSMKFEIGEALYLGIISSLFSLIAGIIL 181
G IL G+ G + ++W I RDF+ PL P + K+E+G ALYLG +SL S++ G+ L
Sbjct: 121 GALHILAGICGMVAISWYAFNITRDFFDPLYPGT-KYELGPALYLGWSASLISILGGLCL 179
Query: 182 CFSCSSQRNRSNYYDAYQAQPLATRSSPRPGQPPKVKSEFNSYSLTGYV 230
C +C + A + P + S F Y YV
Sbjct: 180 CSACCCGSDEDPAASARRPYQAPVSVMPVATSDQEGDSSFGKYGRNAYV 228
>gi|5921465 claudin 10 isoform b [Homo sapiens]
Length = 228
Score = 114 bits (284), Expect = 9e-26
Identities = 66/232 (28%), Positives = 116/232 (50%), Gaps = 6/232 (2%)
Query: 1 MASLGLQLVGYILGLLGLLGTLVAMLLPS--WKTSSYVGASIVTAVGFSKGLWMECATHS 58
MAS +++ +++ + G + LV+ LP+ WK S+ G I TA ++ LW C T S
Sbjct: 1 MASTASEIIAFMVSISGWV--LVSSTLPTDYWKVSTIDGTVITTATYWAN-LWKACVTDS 57
Query: 59 TGITQCDIYSTLLGLPADIQAAQAMMVTSSAISSLACIISVVGMRCTVFCQESRAKDRVA 118
TG++ C + ++L L IQA + +M+ + ++ I ++ GM+CT +AK ++A
Sbjct: 58 TGVSNCKDFPSMLALDGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIA 117
Query: 119 VAGGVFFILGGLLGFIPVAWNLHGILRDFYSPLVPDSMKFEIGEALYLGIISSLFSLIAG 178
G+ FIL GL + + I +F+ PL + K+E+G AL++G + +I G
Sbjct: 118 CLAGIVFILSGLCSMTGCSLYANKITTEFFDPLFVE-QKYELGAALFIGWAGASLCIIGG 176
Query: 179 IILCFSCSSQRNRSNYYDAYQAQPLATRSSPRPGQPPKVKSEFNSYSLTGYV 230
+I CFS S Y +++R+ G+ K + + YV
Sbjct: 177 VIFCFSISDNNKTPRYTYNGATSVMSSRTKYHGGEDFKTTNPSKQFDKNAYV 228
>gi|50345279 claudin 18 isoform 2 [Homo sapiens]
Length = 261
Score = 104 bits (260), Expect = 6e-23
Identities = 59/224 (26%), Positives = 108/224 (48%), Gaps = 13/224 (5%)
Query: 1 MASLGLQLVGYILGLLGLLGTLVAMLLPSWKTSSYVGASIVTAVGFSKGLWMECATHSTG 60
MA Q +G+++ L+G+ G + A + W T + VTAV +GLW C S+G
Sbjct: 1 MAVTACQGLGFVVSLIGIAGIIAATCMDQWSTQDLYN-NPVTAVFNYQGLWRSCVRESSG 59
Query: 61 ITQCDIYSTLLGLPADIQAAQAMMVTSSAISSLACIISVVGMRC-TVFCQESRAKDRVAV 119
T+C Y TLLGLPA +QA +A+M+ + ++ ++S+ ++C + E AK + +
Sbjct: 60 FTECRGYFTLLGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTL 119
Query: 120 AGGVFFILGGLLGFIPVAWNLHGILRDFY-----------SPLVPDSMKFEIGEALYLGI 168
G+ FI+ GL V+ + ++ +F+ + ++ G AL++G
Sbjct: 120 TSGIMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGW 179
Query: 169 ISSLFSLIAGIILCFSCSSQRNRSNYYDAYQAQPLATRSSPRPG 212
++ +LI G+++C +C Y A + +PG
Sbjct: 180 VAGGLTLIGGVMMCIACRGLAPEETNYKAVSYHASGHSVAYKPG 223
>gi|33598916 claudin 10 isoform a [Homo sapiens]
Length = 226
Score = 103 bits (257), Expect = 1e-22
Identities = 59/224 (26%), Positives = 106/224 (47%), Gaps = 2/224 (0%)
Query: 7 QLVGYILGLLGLLGTLVAMLLPSWKTSSYVGASIVTAVGFSKGLWMECATHSTGITQCDI 66
Q+ + G+ G + A WK ++ +S++TA +GLWM CA ++ G C
Sbjct: 5 QIWALVSGVGGFGALVAATTSNEWKVTTRA-SSVITATWVYQGLWMNCAGNALGSFHCRP 63
Query: 67 YSTLLGLPADIQAAQAMMVTSSAISSLACIISVVGMRCTVFCQESRAKDRVAVAGGVFFI 126
+ T+ + IQA + +M+ + ++ I ++ GM+CT +AK ++A G+ FI
Sbjct: 64 HFTIFKVAGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIACLAGIVFI 123
Query: 127 LGGLLGFIPVAWNLHGILRDFYSPLVPDSMKFEIGEALYLGIISSLFSLIAGIILCFSCS 186
L GL + + I +F+ PL + K+E+G AL++G + +I G+I CFS S
Sbjct: 124 LSGLCSMTGCSLYANKITTEFFDPLFVE-QKYELGAALFIGWAGASLCIIGGVIFCFSIS 182
Query: 187 SQRNRSNYYDAYQAQPLATRSSPRPGQPPKVKSEFNSYSLTGYV 230
Y +++R+ G+ K + + YV
Sbjct: 183 DNNKTPRYTYNGATSVMSSRTKYHGGEDFKTTNPSKQFDKNAYV 226
>gi|7705961 claudin 18 isoform 1 [Homo sapiens]
Length = 261
Score = 102 bits (255), Expect = 2e-22
Identities = 58/224 (25%), Positives = 109/224 (48%), Gaps = 13/224 (5%)
Query: 1 MASLGLQLVGYILGLLGLLGTLVAMLLPSWKTSSYVGASIVTAVGFSKGLWMECATHSTG 60
M++ Q+V ++L +LGL G + A + W T + VT+V +GLW C S+G
Sbjct: 1 MSTTTCQVVAFLLSILGLAGCIAATGMDMWSTQDLYD-NPVTSVFQYEGLWRSCVRQSSG 59
Query: 61 ITQCDIYSTLLGLPADIQAAQAMMVTSSAISSLACIISVVGMRC-TVFCQESRAKDRVAV 119
T+C Y T+LGLPA +QA +A+M+ + ++ ++S+ ++C + E AK + +
Sbjct: 60 FTECRPYFTILGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTL 119
Query: 120 AGGVFFILGGLLGFIPVAWNLHGILRDFY-----------SPLVPDSMKFEIGEALYLGI 168
G+ FI+ GL V+ + ++ +F+ + ++ G AL++G
Sbjct: 120 TSGIMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGW 179
Query: 169 ISSLFSLIAGIILCFSCSSQRNRSNYYDAYQAQPLATRSSPRPG 212
++ +LI G+++C +C Y A + +PG
Sbjct: 180 VAGGLTLIGGVMMCIACRGLAPEETNYKAVSYHASGHSVAYKPG 223
>gi|169166402 PREDICTED: claudin-24-like [Homo sapiens]
Length = 220
Score = 102 bits (253), Expect = 4e-22
Identities = 56/185 (30%), Positives = 98/185 (52%), Gaps = 6/185 (3%)
Query: 6 LQLVGYILGLLGLLGTLVAMLLPSWKTSSYVGASIVTAVGFSKGLWMECATHSTGITQCD 65
+Q VG +L LLG + +++ LP WK + + ++ GLW C QC
Sbjct: 9 MQSVGLLLSLLGWILSIITTYLPHWKN---LNLDLNEMENWTMGLWQTCVIQEEVGMQCK 65
Query: 66 IYSTLLGLPADIQAAQAMMVTSSAISSLACIISVVGMRCTVFCQESR-AKDRVAVAGGVF 124
+ + L LPA+++ ++ +M S+ + L ++S G+ C + R K R+ + GG+
Sbjct: 66 DFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGIL 125
Query: 125 FILGGLLGFIPVAWNLHGILRDFYSPLVPDSM-KFEIGEALYLGIISSLFSLIAGIIL-C 182
G+ +PV+W H +++F+ VPD + ++E GEAL+LG + L L+ G +L C
Sbjct: 126 SWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLNC 185
Query: 183 FSCSS 187
+CSS
Sbjct: 186 AACSS 190
>gi|169167239 PREDICTED: claudin-24-like [Homo sapiens]
Length = 220
Score = 100 bits (249), Expect = 1e-21
Identities = 55/185 (29%), Positives = 97/185 (52%), Gaps = 6/185 (3%)
Query: 6 LQLVGYILGLLGLLGTLVAMLLPSWKTSSYVGASIVTAVGFSKGLWMECATHSTGITQCD 65
+Q VG +L LG + +++ LP WK + + ++ GLW C QC
Sbjct: 9 MQSVGLLLSFLGWILSIITTYLPHWKN---LNLDLNEMENWTMGLWQTCVIQEEVGMQCK 65
Query: 66 IYSTLLGLPADIQAAQAMMVTSSAISSLACIISVVGMRCTVFCQESR-AKDRVAVAGGVF 124
+ + L LPA+++ ++ +M S+ + L ++S G+ C + R K R+ + GG+
Sbjct: 66 DFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGIL 125
Query: 125 FILGGLLGFIPVAWNLHGILRDFYSPLVPDSM-KFEIGEALYLGIISSLFSLIAGIIL-C 182
G+ +PV+W H +++F+ VPD + ++E GEAL+LG + L L+ G +L C
Sbjct: 126 SWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLNC 185
Query: 183 FSCSS 187
+CSS
Sbjct: 186 AACSS 190
>gi|169166931 PREDICTED: claudin-24-like [Homo sapiens]
Length = 220
Score = 100 bits (249), Expect = 1e-21
Identities = 55/185 (29%), Positives = 97/185 (52%), Gaps = 6/185 (3%)
Query: 6 LQLVGYILGLLGLLGTLVAMLLPSWKTSSYVGASIVTAVGFSKGLWMECATHSTGITQCD 65
+Q VG +L LG + +++ LP WK + + ++ GLW C QC
Sbjct: 9 MQSVGLLLSFLGWILSIITTYLPHWKN---LNLDLNEMENWTMGLWQTCVIQEEVGMQCK 65
Query: 66 IYSTLLGLPADIQAAQAMMVTSSAISSLACIISVVGMRCTVFCQESR-AKDRVAVAGGVF 124
+ + L LPA+++ ++ +M S+ + L ++S G+ C + R K R+ + GG+
Sbjct: 66 DFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGIL 125
Query: 125 FILGGLLGFIPVAWNLHGILRDFYSPLVPDSM-KFEIGEALYLGIISSLFSLIAGIIL-C 182
G+ +PV+W H +++F+ VPD + ++E GEAL+LG + L L+ G +L C
Sbjct: 126 SWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLNC 185
Query: 183 FSCSS 187
+CSS
Sbjct: 186 AACSS 190
>gi|162417973 claudin 22 [Homo sapiens]
Length = 220
Score = 98.6 bits (244), Expect = 4e-21
Identities = 60/199 (30%), Positives = 100/199 (50%), Gaps = 7/199 (3%)
Query: 7 QLVGYILGLLGLLGTLVAMLLPSWKTSSYVGASIVTAVGFSKGLWMECATHSTGITQCDI 66
QL G L LLG + + + LP WK + + ++ GLW C QC
Sbjct: 10 QLAGVSLSLLGWVLSCLTNYLPHWKN---LNLDLNEMENWTMGLWQTCVIQEEVGMQCKD 66
Query: 67 YSTLLGLPADIQAAQAMMVTSSAISSLACIISVVGMRCTVFCQESR-AKDRVAVAGGVFF 125
+ + L LPA+++ ++ +M S+ + L ++S G+ C + R K R+ + GG+
Sbjct: 67 FDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGILS 126
Query: 126 ILGGLLGFIPVAWNLHGILRDFYSPLVPDSM-KFEIGEALYLGIISSLFSLIAGIIL-CF 183
G+ +PV+W H +++F+ VPD + ++E GEAL+LG + L L+ G +L C
Sbjct: 127 WASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLHCA 186
Query: 184 SCSSQRN-RSNYYDAYQAQ 201
+CSS S +Y Q Q
Sbjct: 187 ACSSHAPLASGHYAVAQTQ 205
>gi|157820127 claudin-like [Homo sapiens]
Length = 229
Score = 92.0 bits (227), Expect = 4e-19
Identities = 54/181 (29%), Positives = 89/181 (49%), Gaps = 5/181 (2%)
Query: 6 LQLVGYILGLLGLLGTLVAMLLPSWKTSSYVGASIVTAVGFSKGLWMECATHSTGITQCD 65
+QL G +L LLG + + V +LP WKT + + T + G+W C T C
Sbjct: 9 VQLGGLLLSLLGWVCSCVTTILPQWKTLNLELNEMETWI---MGIWEVCVDREEVATVCK 65
Query: 66 IYSTLLGLPADIQAAQAMMVTSSAISSLACIISVVGMRCTVFCQESRA-KDRVAVAGGVF 124
+ + L LP ++Q A+ +MV S + L ++ G C F + K R+ + G
Sbjct: 66 AFESFLSLPQELQVARILMVASHGLGLLGLLLCSFGSECFQFHRIRWVFKRRLGLLGRTL 125
Query: 125 FILGGLLGFIPVAWNLHGILRDFYSPLVPDSM-KFEIGEALYLGIISSLFSLIAGIILCF 183
+PV+W H ++DF+ +PD + ++E G ALYLG + +F + G++L F
Sbjct: 126 EASASATTLLPVSWVAHATIQDFWDDSIPDIIPRWEFGGALYLGWAAGIFLALGGLLLIF 185
Query: 184 S 184
S
Sbjct: 186 S 186
>gi|231569235 claudin 10 isoform a_i1 [Homo sapiens]
Length = 207
Score = 89.4 bits (220), Expect = 2e-18
Identities = 56/224 (25%), Positives = 99/224 (44%), Gaps = 21/224 (9%)
Query: 7 QLVGYILGLLGLLGTLVAMLLPSWKTSSYVGASIVTAVGFSKGLWMECATHSTGITQCDI 66
Q+ + G+ G + A WK ++ +S++TA +GLWM CA +
Sbjct: 5 QIWALVSGVGGFGALVAATTSNEWKVTTRA-SSVITATWVYQGLWMNCAGY--------- 54
Query: 67 YSTLLGLPADIQAAQAMMVTSSAISSLACIISVVGMRCTVFCQESRAKDRVAVAGGVFFI 126
IQA + +M+ + ++ I ++ GM+CT +AK ++A G+ FI
Sbjct: 55 ----------IQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIACLAGIVFI 104
Query: 127 LGGLLGFIPVAWNLHGILRDFYSPLVPDSMKFEIGEALYLGIISSLFSLIAGIILCFSCS 186
L GL + + I +F+ PL + K+E+G AL++G + +I G+I CFS S
Sbjct: 105 LSGLCSMTGCSLYANKITTEFFDPLFVE-QKYELGAALFIGWAGASLCIIGGVIFCFSIS 163
Query: 187 SQRNRSNYYDAYQAQPLATRSSPRPGQPPKVKSEFNSYSLTGYV 230
Y +++R+ G+ K + + YV
Sbjct: 164 DNNKTPRYTYNGATSVMSSRTKYHGGEDFKTTNPSKQFDKNAYV 207
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.137 0.415
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,269,215
Number of Sequences: 37866
Number of extensions: 323428
Number of successful extensions: 1371
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 40
Number of HSP's successfully gapped in prelim test: 22
Number of HSP's that attempted gapping in prelim test: 1283
Number of HSP's gapped (non-prelim): 66
length of query: 230
length of database: 18,247,518
effective HSP length: 99
effective length of query: 131
effective length of database: 14,498,784
effective search space: 1899340704
effective search space used: 1899340704
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.