Guide to the Human Genome
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Search of human proteins with 98991767

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|98991767 mitogen-activated protein kinase kinase kinase 7
interacting protein 3 [Homo sapiens]
         (712 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|98991767 mitogen-activated protein kinase kinase kinase 7 int...  1475   0.0  
gi|14149669 mitogen-activated protein kinase kinase kinase 7 int...   384   e-106
gi|151301053 RNA binding motif protein 33 [Homo sapiens]               80   5e-15
gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]             77   6e-14
gi|116284392 mucin 2 precursor [Homo sapiens]                          76   1e-13
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    70   7e-12
gi|150170670 piccolo isoform 2 [Homo sapiens]                          69   2e-11
gi|150378539 piccolo isoform 1 [Homo sapiens]                          69   2e-11
gi|163965366 nascent polypeptide-associated complex alpha subuni...    69   2e-11
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    69   2e-11
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    68   3e-11
gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap...    68   3e-11
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]       67   4e-11
gi|54112403 chromodomain helicase DNA binding protein 7 [Homo sa...    65   2e-10
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]     65   2e-10
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]     65   2e-10
gi|55750053 atrophin-1 [Homo sapiens]                                  65   2e-10
gi|55750041 atrophin-1 [Homo sapiens]                                  65   2e-10
gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [...    65   2e-10
gi|47132519 Ras association and pleckstrin homology domains 1 is...    64   4e-10
gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]       64   6e-10
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          63   8e-10
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]          63   8e-10
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]          63   8e-10
gi|91199543 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo s...    62   2e-09
gi|33636768 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo s...    62   2e-09
gi|34365793 WNK lysine deficient protein kinase 4 [Homo sapiens]       61   4e-09
gi|222352122 hypothetical protein LOC284297 [Homo sapiens]             60   5e-09
gi|31543543 retinoic acid induced 17 [Homo sapiens]                    60   7e-09
gi|54860079 nadrin isoform 1 [Homo sapiens]                            59   1e-08

>gi|98991767 mitogen-activated protein kinase kinase kinase 7
           interacting protein 3 [Homo sapiens]
          Length = 712

 Score = 1475 bits (3819), Expect = 0.0
 Identities = 712/712 (100%), Positives = 712/712 (100%)

Query: 1   MAQSSPQLDIQVLHDLRQRFPEIPEGVVSQCMLQNNNNLEACCRALSQESSKYLYMEYHS 60
           MAQSSPQLDIQVLHDLRQRFPEIPEGVVSQCMLQNNNNLEACCRALSQESSKYLYMEYHS
Sbjct: 1   MAQSSPQLDIQVLHDLRQRFPEIPEGVVSQCMLQNNNNLEACCRALSQESSKYLYMEYHS 60

Query: 61  PDDNRMNRNRLLHINLGIHSPSSYHPGDGAQLNGGRTLVHSSSDGHIDPQHAAGKQLICL 120
           PDDNRMNRNRLLHINLGIHSPSSYHPGDGAQLNGGRTLVHSSSDGHIDPQHAAGKQLICL
Sbjct: 61  PDDNRMNRNRLLHINLGIHSPSSYHPGDGAQLNGGRTLVHSSSDGHIDPQHAAGKQLICL 120

Query: 121 VQEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPPP 180
           VQEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPPP
Sbjct: 121 VQEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPPP 180

Query: 181 PPSYMHIPRYSTNPITVTVSQNLPSGQTVPRALQILPQIPSNLYGSPGSIYIRQTSQSSS 240
           PPSYMHIPRYSTNPITVTVSQNLPSGQTVPRALQILPQIPSNLYGSPGSIYIRQTSQSSS
Sbjct: 181 PPSYMHIPRYSTNPITVTVSQNLPSGQTVPRALQILPQIPSNLYGSPGSIYIRQTSQSSS 240

Query: 241 GRQTPQSTPWQSSPQGPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQIPQSAYHSPPPSQC 300
           GRQTPQSTPWQSSPQGPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQIPQSAYHSPPPSQC
Sbjct: 241 GRQTPQSTPWQSSPQGPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQIPQSAYHSPPPSQC 300

Query: 301 PSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHSVAYLPYTASSLSK 360
           PSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHSVAYLPYTASSLSK
Sbjct: 301 PSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHSVAYLPYTASSLSK 360

Query: 361 GSMKKIEITVEPSQRPGTAINRSPSPISNQPSPWNQHSLYTATTPPSSSPSRGISSQPKP 420
           GSMKKIEITVEPSQRPGTAINRSPSPISNQPSPWNQHSLYTATTPPSSSPSRGISSQPKP
Sbjct: 361 GSMKKIEITVEPSQRPGTAINRSPSPISNQPSPWNQHSLYTATTPPSSSPSRGISSQPKP 420

Query: 421 PFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTTVFKITVGRATTENLLNLVDQEERSAAP 480
           PFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTTVFKITVGRATTENLLNLVDQEERSAAP
Sbjct: 421 PFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTTVFKITVGRATTENLLNLVDQEERSAAP 480

Query: 481 EPIQPISVIPGSGGEKGSHKYQRSSSSGSDDYAYTQALLLHQRARMERLAKQLKLEKEEL 540
           EPIQPISVIPGSGGEKGSHKYQRSSSSGSDDYAYTQALLLHQRARMERLAKQLKLEKEEL
Sbjct: 481 EPIQPISVIPGSGGEKGSHKYQRSSSSGSDDYAYTQALLLHQRARMERLAKQLKLEKEEL 540

Query: 541 ERLKSEVNGMEHDLMQRRLRRVSCTTAIPTPEEMTRLRSMNRQLQINVDCTLKEVDLLQS 600
           ERLKSEVNGMEHDLMQRRLRRVSCTTAIPTPEEMTRLRSMNRQLQINVDCTLKEVDLLQS
Sbjct: 541 ERLKSEVNGMEHDLMQRRLRRVSCTTAIPTPEEMTRLRSMNRQLQINVDCTLKEVDLLQS 600

Query: 601 RGNFDPKAMNNFYDNIEPGPVVPPKPSKKDSSDPCTIERKARRISVTSKVQADIHDTQAA 660
           RGNFDPKAMNNFYDNIEPGPVVPPKPSKKDSSDPCTIERKARRISVTSKVQADIHDTQAA
Sbjct: 601 RGNFDPKAMNNFYDNIEPGPVVPPKPSKKDSSDPCTIERKARRISVTSKVQADIHDTQAA 660

Query: 661 AADEHRTGSTQSPRTQPRDEDYEGAPWNCDSCTFLNHPALNRCEQCEMPRYT 712
           AADEHRTGSTQSPRTQPRDEDYEGAPWNCDSCTFLNHPALNRCEQCEMPRYT
Sbjct: 661 AADEHRTGSTQSPRTQPRDEDYEGAPWNCDSCTFLNHPALNRCEQCEMPRYT 712


>gi|14149669 mitogen-activated protein kinase kinase kinase 7
           interacting protein 2 [Homo sapiens]
          Length = 693

 Score =  384 bits (985), Expect = e-106
 Identities = 286/785 (36%), Positives = 399/785 (50%), Gaps = 167/785 (21%)

Query: 1   MAQSSPQLDIQVLHDLRQRFPEIPEGVVSQCMLQNNNNLEACCRALSQESSKYLYME--Y 58
           MAQ S Q+D QVLHDLRQ+FPE+PE VVS+CMLQNNNNL+ACC  LSQES++YLY E   
Sbjct: 1   MAQGSHQIDFQVLHDLRQKFPEVPEVVVSRCMLQNNNNLDACCAVLSQESTRYLYGEGDL 60

Query: 59  HSPDDNRMN--RNRLLHINLGIHSPSSYHPG-DGAQLNGGRTLVHSSSDGHIDPQHAAGK 115
           +  DD+ ++  RN +  +NL + S + YH G +G+++NG RTL HS SDG +    +  +
Sbjct: 61  NFSDDSGISGLRNHMTSLNLDLQSQNIYHHGREGSRMNGSRTLTHSISDGQLQGGQSNSE 120

Query: 116 QLICLVQEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGP 175
                 QEP +APA V     +N F M+  + ++ + P       S   + ++       
Sbjct: 121 ---LFQQEPQTAPAQVPQ--GFNVFGMSSSSGASNSAPHLGFHLGSKGTSSLSQQT---- 171

Query: 176 SPPPPPPSYMHIPRYSTNPITVTVSQNLPSGQTVPRALQILPQIPSNLYGSP--GSIYIR 233
                       PR+  NPI VT++ N+ +G+  P +L I   +P  +  SP   SIYIR
Sbjct: 172 ------------PRF--NPIMVTLAPNIQTGRNTPTSLHI-HGVPPPVLNSPQGNSIYIR 216

Query: 234 Q--TSQSSSGRQTPQSTPW--QSSPQGPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQIPQ 289
              T+   + RQT Q + W  Q +P  P              QQ YQPSQ  P       
Sbjct: 217 PYITTPGGTTRQTQQHSGWVSQFNPMNP--------------QQVYQPSQPGP------- 255

Query: 290 SAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHSVA 349
             + + P S   S  SS Q   Q  Q  H++MP S  TT      Q P  +    S S A
Sbjct: 256 --WTTCPASNPLSHTSSQQPNQQGHQTSHVYMPISSPTT-----SQPPTIHSSGSSQSSA 308

Query: 350 YLPYTASSLSKGSMK-KIEITVEPSQRPGTAINRSPSP--------ISNQPSPWNQHSLY 400
           +  Y   ++S G  K +IEI +EP QR  ++  RS  P        +++Q    NQ ++Y
Sbjct: 309 HSQYNIQNISTGPRKNQIEIKLEPPQRNNSSKLRSSGPRTSSTSSSVNSQTLNRNQPTVY 368

Query: 401 TATTPPSSSPSRGISSQPKPPFSVNPV----YITYTQPT--------------------- 435
            A +PP++       SQPK   S N       +   QPT                     
Sbjct: 369 IAASPPNTDELMS-RSQPKVYISANAATGDEQVMRNQPTLFISTNSGASAASRNMSGQVS 427

Query: 436 -GPSC-------------TPSPSPRVI---PNPTTVFKITVGR-----------ATTENL 467
            GP+                + SPRV+   PN    FKITV             + T  L
Sbjct: 428 MGPAFIHHHPPKSRAIGNNSATSPRVVVTQPNTKYTFKITVSPNKPPAVSPGVVSPTFEL 487

Query: 468 LNLVDQEERSAAPEPIQPISVIPGSGGEKGSHKYQRSSSSGSDDYAYTQALLLHQRARME 527
            NL++  +     E IQ ++    +  ++ S    R  S GSDD AYTQALL+HQ+ARME
Sbjct: 488 TNLLNHPDHYVETENIQHLTDPTLAHVDRISET--RKLSMGSDDAAYTQALLVHQKARME 545

Query: 528 RLAKQLKLEKEELERLKSEVNGMEHDLMQRRLRRVSCTTAIPTPEEMTRLRSMNRQLQIN 587
           RL ++L+++K++L++LKSEVN ME++L +RRL+R +  + IP+ EEM +LRS NRQLQI+
Sbjct: 546 RLQRELEIQKKKLDKLKSEVNEMENNLTRRRLKRSNSISQIPSLEEMQQLRSCNRQLQID 605

Query: 588 VDCTLKEVDLLQSRG-NFDPKAMNNFYDNIEPGPVVPPKPSKKDSSDPCTIERKARRISV 646
           +DC  KE+DL Q+RG +F+P A++NFYDNI     VPPKP  + S               
Sbjct: 606 IDCLTKEIDLFQARGPHFNPSAIHNFYDNIGFVGPVPPKPKDQRS--------------- 650

Query: 647 TSKVQADIHDTQAAAADEHRTGSTQSPRTQPRDEDYEGAPWNCDSCTFLNHPALNRCEQC 706
                                   ++P+TQ  ++D EGA WNC +CTFLNHPAL RCEQC
Sbjct: 651 ----------------------IIKTPKTQDTEDD-EGAQWNCTACTFLNHPALIRCEQC 687

Query: 707 EMPRY 711
           EMPR+
Sbjct: 688 EMPRH 692


>gi|151301053 RNA binding motif protein 33 [Homo sapiens]
          Length = 1170

 Score = 80.5 bits (197), Expect = 5e-15
 Identities = 93/322 (28%), Positives = 124/322 (38%), Gaps = 57/322 (17%)

Query: 152 PPSQPPQQPSSMQTGMN-----PSAM----QGPSPPPPPPSYMH----IPRYSTNPITVT 198
           PP  PPQ       G++     PS +    + P PPPPPP+ ++    +P  S  P T  
Sbjct: 452 PP--PPQDRDPFFLGVSGEPRFPSHLFLEQRSPPPPPPPPTLLNSSHPVPTQSPLPFTQP 509

Query: 199 VSQNLPSGQ--TVPRALQILPQIPSNLYGSPGSIYIRQTSQSSSGRQTPQSTPWQSSPQG 256
                  GQ    PR   + P +       PG + I   SQ  S    P   P Q    G
Sbjct: 510 GPAFNQQGQQPVFPRERPVRPALQP-----PGPVGILHFSQPGSATTRPFIPPRQPFLPG 564

Query: 257 P----VPHYSQR--------PLPVYPHQ-QNYQPSQYSPKQQQIPQSAYHSPPPSQCPSP 303
           P    +P ++Q         PLP  PHQ Q  QP Q  P Q Q P    H PPP   P P
Sbjct: 565 PGQPFLPTHTQPNLQGPLHPPLPP-PHQPQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPP 623

Query: 304 FSSPQHQVQPS---QLGHIFMPPSPSTTPPHP-YQQGPPSYQKQGSHSVAYLPY------ 353
              PQH  Q        H+ +PP P      P ++    + Q Q S S    P       
Sbjct: 624 QHPPQHPPQHQHHHHHHHLSVPPPPLMPMSQPQFRPHVQTAQPQASSSRMQCPQRQGLRH 683

Query: 354 --TASSLSKGSMKKIEITVEPSQR-------PGTAINRSPSPISNQPSPWNQHSLYTATT 404
             T+ ++SK  M++++ T   +         P   I  S S  S  PS   Q     + +
Sbjct: 684 NTTSQNVSKRPMQQMQPTAPRNSNLRELPIAPSHVIEMSSSRCSATPSA--QVKPIVSAS 741

Query: 405 PPSSSPSRGISSQPKPPFSVNP 426
           PPS + +   SSQ K    V P
Sbjct: 742 PPSRAVAGSRSSQGKTEVKVKP 763



 Score = 60.5 bits (145), Expect = 5e-09
 Identities = 81/314 (25%), Positives = 113/314 (35%), Gaps = 61/314 (19%)

Query: 150 ATPPSQPPQQPSSMQTGMNPSAMQGPSP-----PPPPPSYMHIPRYSTNPITVTVSQNLP 204
           A PP  PP Q   +++   P  +Q   P      P PP  MH+P     P  +       
Sbjct: 319 APPPPPPPPQQQPIRSLFQPQPLQPLLPVQHPHHPSPPQGMHMPPQLETPRMM------- 371

Query: 205 SGQTVPRALQILPQIPSNLYGSPGSIYIRQTSQSSSGRQTPQSTPWQSSPQGPVPHYSQR 264
              T P    + PQ P N++ +P   + + T        TP   P    P  P P    +
Sbjct: 372 --MTPP---PVTPQQPKNIHINP---HFKGTV------VTPVQVPLLPVPSQPRPAVGPQ 417

Query: 265 PLPVYP----HQQNYQPSQYSPKQQQIPQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIF 320
             P  P    H     P+ +S   +   Q  + +PPP Q   PF       +P    H+F
Sbjct: 418 RFPGPPEFPQHTPGPVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGV-SGEPRFPSHLF 476

Query: 321 MPPSPSTTPPHPYQQGPPSYQKQGSHSV---AYLPYTASSLSKGSMKKIEITVEPSQRPG 377
           +       PP      PP      SH V   + LP+T         ++ +  V P +RP 
Sbjct: 477 LEQRSPPPPP------PPPTLLNSSHPVPTQSPLPFTQP--GPAFNQQGQQPVFPRERPV 528

Query: 378 TAINRSPSPIS----NQPSPWNQHSLYTATTPPSSSPSRGISSQPKPPFSVNPVYITYTQ 433
               + P P+     +QP         +ATT P   P      QP  P    P   T+TQ
Sbjct: 529 RPALQPPGPVGILHFSQPG--------SATTRPFIPP-----RQPFLPGPGQPFLPTHTQ 575

Query: 434 PT--GPSCTPSPSP 445
           P   GP   P P P
Sbjct: 576 PNLQGPLHPPLPPP 589



 Score = 40.0 bits (92), Expect = 0.007
 Identities = 62/265 (23%), Positives = 90/265 (33%), Gaps = 33/265 (12%)

Query: 251 QSSPQGPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQIPQSAYHSPPPSQCPSPFSSPQHQ 310
           +S+ +G +  +    LP  P      P    P  QQ P  +   P P Q   P   P H 
Sbjct: 294 ESTERGRMKDHRPALLPTQPPVVPQAPPPPPPPPQQQPIRSLFQPQPLQPLLPVQHPHH- 352

Query: 311 VQPSQLGHIFMPPSPST-----TPPHPYQQGPPS-YQKQGSHSVAYLPYTASSLSKGSMK 364
             PS    + MPP   T     TPP    Q P + +           P     L   S  
Sbjct: 353 --PSPPQGMHMPPQLETPRMMMTPPPVTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQP 410

Query: 365 KIEITVEPSQRPGTAINRSPSPISN---QPSPWNQHSLYTATTPPSSSPS--RGISSQPK 419
           +  +  +    P      +P P+ N   QP        + A  PP        G+S +P+
Sbjct: 411 RPAVGPQRFPGPPEFPQHTPGPVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGEPR 470

Query: 420 PPFSVNPVYITYTQPTGPSCTPS------PSPRVIPNPTTVFKITVGRATTENLLNLVDQ 473
            P   + +++    P  P   P+      P P   P P T      G A  +     V  
Sbjct: 471 FP---SHLFLEQRSPPPPPPPPTLLNSSHPVPTQSPLPFT----QPGPAFNQQGQQPVFP 523

Query: 474 EERSAAP--EPIQPISVI----PGS 492
            ER   P  +P  P+ ++    PGS
Sbjct: 524 RERPVRPALQPPGPVGILHFSQPGS 548



 Score = 35.4 bits (80), Expect = 0.18
 Identities = 42/187 (22%), Positives = 65/187 (34%), Gaps = 12/187 (6%)

Query: 144 EQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPPPPPSYMHIPRYSTNPITVTVSQNL 203
           +Q +    P  QPP QP       +    Q P   PP   + H   + + P    +  + 
Sbjct: 595 QQPQQQPPPQHQPPHQPPHQPPPQHQPPPQHPPQHPPQHQHHHHHHHLSVPPPPLMPMSQ 654

Query: 204 PSGQTVPRALQILPQIPSNLYGSPGSIYIRQTSQSSSGRQTPQSTPWQSSPQGPVPHYSQ 263
           P  Q  P      PQ  S+    P    +R  + S +  + P     Q  P  P  + + 
Sbjct: 655 P--QFRPHVQTAQPQASSSRMQCPQRQGLRHNTTSQNVSKRPMQ---QMQPTAP-RNSNL 708

Query: 264 RPLPVYP-HQQNYQPSQYSPKQQQIPQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMP 322
           R LP+ P H      S+ S       +    + PPS+  +   S Q + +         P
Sbjct: 709 RELPIAPSHVIEMSSSRCSATPSAQVKPIVSASPPSRAVAGSRSSQGKTEVK-----VKP 763

Query: 323 PSPSTTP 329
            SP   P
Sbjct: 764 ASPVAQP 770


>gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]
          Length = 1970

 Score = 77.0 bits (188), Expect = 6e-14
 Identities = 109/387 (28%), Positives = 149/387 (38%), Gaps = 41/387 (10%)

Query: 77   GIHSPSS-YHPGDGAQLNGGRTLVHSSSDGHIDPQHAAGKQLICLVQEPHSAPAVVAATP 135
            G   PSS Y P  G    G  +  +S +    +P+   G         P S P+    +P
Sbjct: 1573 GSPGPSSPYIPSPG----GAMSPSYSPTSPAYEPRSPGGYTPQSPSYSPTS-PSYSPTSP 1627

Query: 136  NYNPFFMNEQNRSAATPPSQPPQQPSS-MQTGMNPS-AMQGPSPPPPPPSYMHI-PRYST 192
            +Y+P   N    S +  P+ P   P+S   +  +PS +   PS  P  PSY    P YS 
Sbjct: 1628 SYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYS- 1686

Query: 193  NPITVTVSQNLPSGQTVPRALQILPQIPSNLYGSPGSIYIRQTSQSSSGRQTPQSTPWQS 252
             P + + S   PS    P +    P  PS    SP S     TS S S   +P  +P   
Sbjct: 1687 -PTSPSYSPTSPSYS--PTSPSYSPTSPSY---SPTSPSYSPTSPSYS-PTSPSYSPTSP 1739

Query: 253  SPQGPVPHYSQRPLPVYPHQQNYQPS--QYSPKQQQIPQSAYHSPPPSQCPSPFSSPQHQ 310
            S     P+YS       P   +Y P+   YSP       ++ +  P S   SP S     
Sbjct: 1740 SYSPTSPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPTSPSYSP 1799

Query: 311  VQPSQLGHIFMPPSPSTTPPHP-YQQGPPSYQKQG-SHSVAYLPYTASSLSKGSMKKIEI 368
              PS     + P SP  TP  P Y    PSY     S+S     YT +S S         
Sbjct: 1800 TSPS-----YSPSSPRYTPQSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPEYT 1854

Query: 369  TVEPSQRPGTAINRSPSPISNQPSPWNQHSLYTATTP------PSSSPSRGISSQPKPPF 422
               P   P +      SP  +  SP      Y+ TTP      P+ SP+  + +   P +
Sbjct: 1855 PTSPKYSPTSPKYSPTSPKYSPTSP-----TYSPTTPKYSPTSPTYSPTSPVYTPTSPKY 1909

Query: 423  SVNPVYITYTQPTGPSCTPSPSPRVIP 449
            S  P   TY+ PT P  +P+ SP   P
Sbjct: 1910 S--PTSPTYS-PTSPKYSPT-SPTYSP 1932



 Score = 71.2 bits (173), Expect = 3e-12
 Identities = 99/346 (28%), Positives = 138/346 (39%), Gaps = 31/346 (8%)

Query: 126  SAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQ-TGMNPS-AMQGPSPPPPPPS 183
            ++P+    +PNY+P   +    S +  P+ P   P+S   +  +PS +   PS  P  PS
Sbjct: 1625 TSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPS 1684

Query: 184  YMHI-PRYSTNPITVTVSQNLPS-GQTVPRALQILPQI-PSNLYGSPGSIYIRQTSQSSS 240
            Y    P YS  P + + S   PS   T P      P   P++   SP S     TS S S
Sbjct: 1685 YSPTSPSYS--PTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYS 1742

Query: 241  GRQTPQSTPWQSSPQGPVPHYSQRPLPVYPHQQNYQPSQ--YSPKQQQI-PQSAYHSPP- 296
               +P  +P   +     P YS       P   NY P+   YSP      P S  +SP  
Sbjct: 1743 PT-SPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPTSPSYSPTS 1801

Query: 297  PSQCPS-PFSSPQHQVQ-PSQLGHIFMPPSPSTTPPHP-YQQGPPSYQKQGSHSVAYLP- 352
            PS  PS P  +PQ     PS     + P SPS +P  P Y    PSY           P 
Sbjct: 1802 PSYSPSSPRYTPQSPTYTPSSPS--YSPSSPSYSPTSPKYTPTSPSYSPSSPEYTPTSPK 1859

Query: 353  YTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQPSPWNQHSLYTATTP------P 406
            Y+ +S              P+  P T      SP  +  SP     +YT T+P      P
Sbjct: 1860 YSPTSPKYSPTSPKYSPTSPTYSPTTPKYSPTSPTYSPTSP-----VYTPTSPKYSPTSP 1914

Query: 407  SSSPSRGISSQPKPPFS-VNPVYITYTQPTGPSCTPSPSPRVIPNP 451
            + SP+    S   P +S  +P   TY+ PT P  +P+     + +P
Sbjct: 1915 TYSPTSPKYSPTSPTYSPTSPKGSTYS-PTSPGYSPTSPTYSLTSP 1959



 Score = 65.9 bits (159), Expect = 1e-10
 Identities = 93/300 (31%), Positives = 120/300 (40%), Gaps = 27/300 (9%)

Query: 160  PSSMQTGMNPSAMQGPSPPPPPPSYMHIPRYSTNPITVTVSQNLPSGQTVPRALQILPQI 219
            P+ M  G  PS M G SP   P +    P Y         S ++ SG T P A    P  
Sbjct: 1498 PTGMFFGSAPSPMGGISPAMTPWNQGATPAYGA------WSPSVGSGMT-PGAAGFSPSA 1550

Query: 220  PSNLYG-SPGSIYIRQTSQSSSGRQTPQSTPWQSSPQGPV-PHYSQRPLPVYPHQQNYQP 277
             S+  G SPG       +  S G   P S+P+  SP G + P YS    P  P  +   P
Sbjct: 1551 ASDASGFSPGYSPAWSPTPGSPGSPGP-SSPYIPSPGGAMSPSYS----PTSPAYEPRSP 1605

Query: 278  SQYSPKQQQI-PQSAYHSPP-PSQCP-SPFSSPQH-QVQPSQLGHIFMPPSPSTTPPHPY 333
              Y+P+     P S  +SP  PS  P SP  SP      P+   +    PS S T P  Y
Sbjct: 1606 GGYTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSP-SY 1664

Query: 334  QQGPPSYQKQG-SHSVAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQPS 392
                PSY     S+S     Y+ +S S            PS  P T+ + SP+  S  P+
Sbjct: 1665 SPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSP-TSPSYSPTSPSYSPT 1723

Query: 393  PWNQHSLYTATTPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPT 452
                 S   + T PS SP+    S   P +S      T T P+    +PS SP   PN T
Sbjct: 1724 -----SPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYTPTSPSYSPTSPSYSP-TSPNYT 1777



 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 90/331 (27%), Positives = 125/331 (37%), Gaps = 29/331 (8%)

Query: 126  SAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQ-TGMNPS-AMQGPSPPPPPPS 183
            ++P+    +P+Y+P   +    S +  P+ P   P+S   +  +PS +   PS  P  PS
Sbjct: 1653 TSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPS 1712

Query: 184  YMHI-PRYSTNPITVTVSQNLPS-GQTVPRALQILPQI-PSNLYGSPGSIYIRQTSQSSS 240
            Y    P YS  P + + S   PS   T P      P   P++   +P S     TS S S
Sbjct: 1713 YSPTSPSYS--PTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYTPTSPSYSPTSPSYS 1770

Query: 241  GRQTPQSTPWQSSPQGPVPHYSQRPLPVYPHQQNYQPS--QYSPKQQQIPQSAYHSPPPS 298
               +P  TP   +     P YS       P   +Y PS  +Y+P+      S+    P S
Sbjct: 1771 PT-SPNYTPTSPNYSPTSPSYSPTSPSYSPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSS 1829

Query: 299  QCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHP-YQQGPPSYQ----KQGSHSVAYLPY 353
               SP S       PS     + P SP  TP  P Y    P Y     K    S  Y P 
Sbjct: 1830 PSYSPTSPKYTPTSPS-----YSPSSPEYTPTSPKYSPTSPKYSPTSPKYSPTSPTYSPT 1884

Query: 354  TASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQPSPWNQHSLYTATTPPSSSPSRG 413
            T              T  P+    T  +   SP S   SP +     T+ T   +SP   
Sbjct: 1885 TPK------YSPTSPTYSPTSPVYTPTSPKYSPTSPTYSPTSPKYSPTSPTYSPTSPKGS 1938

Query: 414  ISSQPKPPFSVNPVYITYTQPTGPSCTPSPS 444
              S   P +S  P   TY+  T P+ +P  S
Sbjct: 1939 TYSPTSPGYS--PTSPTYSL-TSPAISPDDS 1966



 Score = 39.7 bits (91), Expect = 0.010
 Identities = 70/264 (26%), Positives = 95/264 (35%), Gaps = 72/264 (27%)

Query: 199  VSQNLPSGQTVPRALQILP------------QIPSNLYG----SPGSIYIRQTSQSSSGR 242
            VS+N+  GQ  P                   +IP+N+ G     P  ++   ++ S  G 
Sbjct: 1454 VSENIMLGQLAPAGTGCFDLLLDAEKCKYGMEIPTNIPGLGAAGPTGMFFG-SAPSPMGG 1512

Query: 243  QTPQSTPWQSSPQGPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQIPQSAYHSPPPSQCPS 302
             +P  TPW    QG  P Y             + PS  S      P +A  SP  +   S
Sbjct: 1513 ISPAMTPWN---QGATPAYGA-----------WSPSVGSG---MTPGAAGFSPSAASDAS 1555

Query: 303  PFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHSVAYLPYTASSLSKGS 362
             FS P +             P+ S TP  P   GP S            PY  S    G+
Sbjct: 1556 GFS-PGYS------------PAWSPTPGSPGSPGPSS------------PYIPSP--GGA 1588

Query: 363  MKKIEITVEPSQRPGTAINRSPSPISNQPSPWNQHSLYTATTPPSSSPSRGISSQPKPPF 422
            M        P+  P     RSP   + Q   ++  S   + T PS SP+    S   P +
Sbjct: 1589 MSPSYSPTSPAYEP-----RSPGGYTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSY 1643

Query: 423  S-VNPVYITYTQPTGPSCTP-SPS 444
            S  +P Y     PT PS +P SPS
Sbjct: 1644 SPTSPSY----SPTSPSYSPTSPS 1663


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score = 75.9 bits (185), Expect = 1e-13
 Identities = 88/365 (24%), Positives = 124/365 (33%), Gaps = 52/365 (14%)

Query: 152  PPSQPPQQPSSMQTGMNPSAMQGPSPP------PPPPSYMHIPRYSTNPITVTVSQNLPS 205
            PP+  P  P +  T   P+    PSPP      PPP +    P  + +P T T S    +
Sbjct: 1433 PPTTTPSPPITTTTTPPPTTT--PSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTT 1490

Query: 206  GQTVPRALQILPQIPSNLYGSPGSIYIRQTSQSSSGRQTPQSTPWQSSPQGPVPHYSQRP 265
              T P      P   + +     +  +  T+  S    T  + P  ++P  P       P
Sbjct: 1491 TTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPP 1550

Query: 266  LPVYPHQQNYQPSQYSPKQQQIPQSAYHSPPPSQCPSP----FSSPQHQVQPSQLGHIFM 321
                       PS         P +   SPP +  PSP     ++P     PS       
Sbjct: 1551 TSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPS------- 1603

Query: 322  PPSPSTTPPHPYQQGPPSYQKQGSHSVAYLPYTASSLSKGSMKKIEITVEPSQRPGTAIN 381
            PP+ +TT P P     P             P T       S   +  T  PS  P T   
Sbjct: 1604 PPTTTTTTPPPTTTPSP-------------PTTTPITPPTSTTTLPPTTTPSPPPTTTTT 1650

Query: 382  RSPSPISNQPSPWNQHSLYTATT--PPSSSPSRGISSQPKPPFSVNPVYITYTQPTGP-- 437
              P+   + P+        T TT  PP+++PS  I++ P PP +        T P+ P  
Sbjct: 1651 PPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPIT 1710

Query: 438  -SCTPS--------------PSPRVIPNPTTVFKITVGRATTENLLNLVDQEERSAAPEP 482
             + TPS              PSP   P+P T    T+   TT + L        S  P  
Sbjct: 1711 TTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPP-SITPPT 1769

Query: 483  IQPIS 487
              P S
Sbjct: 1770 FSPFS 1774



 Score = 70.1 bits (170), Expect = 7e-12
 Identities = 84/337 (24%), Positives = 125/337 (37%), Gaps = 45/337 (13%)

Query: 151  TPPSQPPQQPSSMQTGMNPSAMQGPSPPP-----PPPSYMHIPRYSTN---PITVTVSQN 202
            +PP+  P  P +  T + P+    PSPP      PPP+    P  +T    P T T S  
Sbjct: 1400 SPPTTTPSPPPTSTTTLPPTTT--PSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPP 1457

Query: 203  LPSGQTVPRALQILPQIPSNLYGSPGSIYIRQTSQSSSGRQTPQSTPWQSSPQGPVPHYS 262
            + +  T P      P  P+     P +     T+ +++   T   +P  ++P  P    +
Sbjct: 1458 ISTTTTPPPTTT--PSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTT 1515

Query: 263  QRPLPVYPHQQNYQPSQYSPKQQQIPQSAYHSPPPSQCPSP-----FSSPQHQVQPSQLG 317
              P    P          SP     P +   +PPP+  PSP      + P          
Sbjct: 1516 TLPPTTTP----------SP-----PTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTT 1560

Query: 318  HIFMPPSPSTTPPHPYQQGPPSYQKQGSHSVAYL---PYTASSLSKGSMKKIEITVEPSQ 374
                PP+ +TTPP      PP+       ++      P T  S    +      T  PS 
Sbjct: 1561 TPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSP 1620

Query: 375  RPGTAINRSPS----PISNQPSPWNQHSLYTATTPPSSSPSRGISSQPKPPFSVNPVYIT 430
               T I    S    P +  PSP       T T PP+++PS   ++ P PP +       
Sbjct: 1621 PTTTPITPPTSTTTLPPTTTPSP---PPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPP 1677

Query: 431  YTQPTGP-SCTPSP--SPRVIPNPTTVFKITVGRATT 464
             T P+ P + TPSP  +    P+PTT     +   TT
Sbjct: 1678 TTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTT 1714



 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 74/300 (24%), Positives = 102/300 (34%), Gaps = 52/300 (17%)

Query: 175  PSPP-----PPPPSYMHIPRYSTNPITVTVSQNLPSGQTVPRALQILPQIPSNLYGSPGS 229
            PSPP     PPP S   +P  +T P   T +   P   T P      P I +     P  
Sbjct: 1399 PSPPTTTPSPPPTSTTTLPP-TTTPSPPTTTTTTPPPTTTPS-----PPITTTTTPPP-- 1450

Query: 230  IYIRQTSQSSSGRQTPQSTPWQSSPQGPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQIPQ 289
                          T   +P  S+   P P  +  P    P      PS         P 
Sbjct: 1451 --------------TTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSP--------PT 1488

Query: 290  SAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHSVA 349
            +   +PPP+  PSP   P             +PP+ + +PP      PP           
Sbjct: 1489 TTTTTPPPTTTPSP---PTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSP---- 1541

Query: 350  YLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPS-----PISNQPSPWNQHSLYTATT 404
              P T       S   +  T  PS  P T     P+     P +  PSP    ++ T T 
Sbjct: 1542 --PTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSP---PTITTTTP 1596

Query: 405  PPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTTVFKITVGRATT 464
            PP+++PS   ++   PP +  P   T T  T P+ T +  P   P+P      T    TT
Sbjct: 1597 PPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTT 1656



 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 64/260 (24%), Positives = 91/260 (35%), Gaps = 23/260 (8%)

Query: 151  TPPSQPPQQPSSMQTGMNPSAMQGPSPPP-----PPPSYMHIPRYSTNPITVTVSQNLPS 205
            +PP+  P  P +  T + P+    PSPPP     PPP+    P  +T P   T++   P 
Sbjct: 1540 SPPTTTPITPPTSTTTLPPTTT--PSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPP 1597

Query: 206  GQTVPRALQILPQIPSNLYGSPGSIYIRQTSQSSSGRQTPQSTPWQSSPQGPVPHYSQRP 265
              T P         P+    +P       T+  S    TP + P  ++   P    S  P
Sbjct: 1598 PTTTPSP-------PTTTTTTPPP-----TTTPSPPTTTPITPPTSTTTLPPTTTPSPPP 1645

Query: 266  LPVYPHQQNYQPSQYSPKQQQIPQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSP 325
                       PS  +      P +   +PPP+  PS   SP     PS        PSP
Sbjct: 1646 TTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPS---SPI-TTTPSPPTTTMTTPSP 1701

Query: 326  STTPPHPYQQGPPSYQKQGSHSVAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPS 385
            +TTP  P                     T S  +  S     +T  P     + +  +P 
Sbjct: 1702 TTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPL 1761

Query: 386  PISNQPSPWNQHSLYTATTP 405
            P S  P  ++  S  T TTP
Sbjct: 1762 PPSITPPTFSPFSTTTPTTP 1781



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 73/353 (20%), Positives = 119/353 (33%), Gaps = 50/353 (14%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 4010 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 4064

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 4065 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 4121

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 4122 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 4172

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +      P+      +    ++ PP      P S   Q S S
Sbjct: 4173 PTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPP------PESSTPQTSRS 4226

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQPSPWNQHSLYTATTPPS 407
             +     +++L       IE+T        TA   +    +  P P       + TT P 
Sbjct: 4227 TSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPP-------STTTSPP 4279

Query: 408  SSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVI------PNPTTV 454
             +P+RG ++      + + V  T T    P+ TP  +P +I      P P++V
Sbjct: 4280 GTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSV 4332



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 72/363 (19%), Positives = 119/363 (32%), Gaps = 62/363 (17%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 3895 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3949

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 3950 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 4006

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 4007 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 4057

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 4058 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 4103

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 4104 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 4152

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTTVFKITVGRAT 463
            TP +++ +  ++  P P  +  P     T  T  + TP+P+      PT      +   T
Sbjct: 4153 TPITTTTT--VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELT 4210

Query: 464  TEN 466
            T N
Sbjct: 4211 TSN 4213



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 1917 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 1971

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 1972 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 2028

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 2029 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2079

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 2080 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 2125

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 2126 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2174

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 2175 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 2220



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 1940 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 1994

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 1995 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 2051

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 2052 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2102

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 2103 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 2148

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 2149 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2197

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 2198 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 2243



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 1963 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2017

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 2018 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 2074

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 2075 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2125

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 2126 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 2171

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 2172 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2220

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 2221 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 2266



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 1986 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2040

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 2041 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 2097

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 2098 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2148

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 2149 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 2194

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 2195 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2243

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 2244 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 2289



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 2009 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2063

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 2064 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 2120

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 2121 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2171

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 2172 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 2217

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 2218 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2266

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 2267 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 2312



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 2032 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2086

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 2087 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 2143

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 2144 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2194

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 2195 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 2240

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 2241 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2289

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 2290 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 2335



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 2055 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2109

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 2110 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 2166

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 2167 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2217

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 2218 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 2263

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 2264 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2312

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 2313 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 2358



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 2078 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2132

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 2133 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 2189

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 2190 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2240

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 2241 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 2286

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 2287 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2335

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 2336 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 2381



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 2101 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2155

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 2156 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 2212

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 2213 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2263

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 2264 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 2309

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 2310 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2358

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 2359 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 2404



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 2124 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2178

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 2179 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 2235

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 2236 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2286

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 2287 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 2332

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 2333 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2381

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 2382 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 2427



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 2147 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2201

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 2202 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 2258

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 2259 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2309

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 2310 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 2355

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 2356 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2404

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 2405 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 2450



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 2170 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2224

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 2225 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 2281

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 2282 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2332

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 2333 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 2378

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 2379 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2427

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 2428 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 2473



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 2193 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2247

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 2248 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 2304

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 2305 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2355

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 2356 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 2401

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 2402 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2450

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 2451 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 2496



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 2216 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2270

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 2271 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 2327

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 2328 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2378

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 2379 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 2424

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 2425 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2473

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 2474 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 2519



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 2239 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2293

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 2294 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 2350

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 2351 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2401

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 2402 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 2447

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 2448 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2496

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 2497 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 2542



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 2262 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2316

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 2317 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 2373

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 2374 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2424

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 2425 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 2470

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 2471 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2519

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 2520 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 2565



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 2285 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2339

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 2340 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 2396

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 2397 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2447

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 2448 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 2493

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 2494 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2542

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 2543 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 2588



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 2308 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2362

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 2363 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 2419

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 2420 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2470

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 2471 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 2516

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 2517 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2565

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 2566 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 2611



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 2331 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2385

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 2386 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 2442

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 2443 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2493

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 2494 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 2539

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 2540 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2588

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 2589 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 2634



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 2354 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2408

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 2409 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 2465

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 2466 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2516

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 2517 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 2562

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 2563 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2611

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 2612 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 2657



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 2377 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2431

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 2432 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 2488

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 2489 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2539

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 2540 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 2585

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 2586 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2634

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 2635 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 2680



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 2400 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2454

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 2455 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 2511

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 2512 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2562

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 2563 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 2608

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 2609 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2657

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 2658 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 2703



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 2423 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2477

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 2478 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 2534

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 2535 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2585

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 2586 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 2631

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 2632 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2680

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 2681 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 2726



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 2446 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2500

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 2501 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 2557

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 2558 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2608

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 2609 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 2654

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 2655 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2703

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 2704 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 2749



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 2469 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2523

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 2524 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 2580

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 2581 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2631

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 2632 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 2677

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 2678 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2726

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 2727 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 2772



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 2492 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2546

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 2547 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 2603

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 2604 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2654

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 2655 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 2700

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 2701 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2749

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 2750 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 2795



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 2515 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2569

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 2570 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 2626

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 2627 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2677

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 2678 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 2723

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 2724 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2772

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 2773 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 2818



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 2538 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2592

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 2593 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 2649

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 2650 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2700

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 2701 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 2746

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 2747 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2795

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 2796 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 2841



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 2561 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2615

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 2616 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 2672

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 2673 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2723

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 2724 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 2769

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 2770 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2818

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 2819 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 2864



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 2584 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2638

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 2639 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 2695

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 2696 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2746

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 2747 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 2792

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 2793 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2841

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 2842 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 2887



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 2607 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2661

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 2662 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 2718

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 2719 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2769

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 2770 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 2815

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 2816 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2864

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 2865 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 2910



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 2630 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2684

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 2685 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 2741

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 2742 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2792

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 2793 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 2838

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 2839 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2887

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 2888 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 2933



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 2653 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2707

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 2708 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 2764

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 2765 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2815

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 2816 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 2861

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 2862 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2910

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 2911 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 2956



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 2676 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2730

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 2731 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 2787

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 2788 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2838

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 2839 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 2884

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 2885 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2933

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 2934 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 2979



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 2699 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2753

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 2754 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 2810

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 2811 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2861

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 2862 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 2907

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 2908 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2956

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 2957 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 3002



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 2722 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2776

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 2777 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 2833

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 2834 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2884

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 2885 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 2930

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 2931 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2979

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 2980 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 3025



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 2745 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2799

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 2800 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 2856

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 2857 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2907

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 2908 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 2953

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 2954 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3002

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 3003 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 3048



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 2768 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2822

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 2823 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 2879

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 2880 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2930

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 2931 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 2976

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 2977 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3025

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 3026 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 3071



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 2791 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2845

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 2846 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 2902

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 2903 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2953

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 2954 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 2999

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 3000 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3048

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 3049 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 3094



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 2814 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2868

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 2869 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 2925

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 2926 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2976

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 2977 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 3022

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 3023 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3071

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 3072 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 3117



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 2837 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2891

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 2892 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 2948

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 2949 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2999

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 3000 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 3045

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 3046 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3094

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 3095 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 3140



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 2860 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2914

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 2915 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 2971

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 2972 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3022

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 3023 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 3068

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 3069 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3117

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 3118 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 3163



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 2883 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2937

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 2938 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 2994

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 2995 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3045

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 3046 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 3091

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 3092 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3140

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 3141 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 3186



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 2906 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2960

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 2961 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 3017

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 3018 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3068

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 3069 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 3114

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 3115 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3163

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 3164 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 3209



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 2929 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2983

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 2984 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 3040

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 3041 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3091

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 3092 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 3137

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 3138 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3186

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 3187 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 3232



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 2952 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3006

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 3007 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 3063

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 3064 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3114

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 3115 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 3160

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 3161 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3209

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 3210 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 3255



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 2975 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3029

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 3030 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 3086

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 3087 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3137

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 3138 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 3183

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 3184 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3232

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 3233 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 3278



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 2998 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3052

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 3053 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 3109

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 3110 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3160

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 3161 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 3206

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 3207 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3255

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 3256 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 3301



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 3021 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3075

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 3076 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 3132

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 3133 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3183

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 3184 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 3229

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 3230 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3278

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 3279 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 3324



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 3044 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3098

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 3099 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 3155

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 3156 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3206

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 3207 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 3252

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 3253 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3301

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 3302 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 3347



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 3067 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3121

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 3122 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 3178

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 3179 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3229

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 3230 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 3275

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 3276 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3324

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 3325 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 3370



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 3090 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3144

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 3145 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 3201

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 3202 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3252

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 3253 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 3298

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 3299 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3347

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 3348 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 3393



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 3113 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3167

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 3168 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 3224

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 3225 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3275

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 3276 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 3321

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 3322 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3370

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 3371 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 3416



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 3136 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3190

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 3191 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 3247

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 3248 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3298

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 3299 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 3344

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 3345 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3393

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 3394 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 3439



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 3159 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3213

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 3214 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 3270

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 3271 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3321

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 3322 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 3367

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 3368 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3416

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 3417 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 3462



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 3182 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3236

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 3237 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 3293

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 3294 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3344

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 3345 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 3390

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 3391 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3439

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 3440 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 3485



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 3205 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3259

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 3260 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 3316

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 3317 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3367

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 3368 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 3413

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 3414 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3462

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 3463 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 3508



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 3228 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3282

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 3283 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 3339

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 3340 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3390

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 3391 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 3436

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 3437 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3485

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 3486 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 3531



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 3251 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3305

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 3306 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 3362

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 3363 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3413

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 3414 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 3459

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 3460 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3508

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 3509 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 3554



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 3274 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3328

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 3329 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 3385

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 3386 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3436

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 3437 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 3482

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 3483 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3531

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 3532 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 3577



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 3297 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3351

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 3352 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 3408

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 3409 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3459

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 3460 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 3505

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 3506 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3554

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 3555 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 3600



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 3320 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3374

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 3375 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 3431

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 3432 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3482

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 3483 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 3528

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 3529 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3577

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 3578 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 3623



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 3343 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3397

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 3398 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 3454

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 3455 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3505

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 3506 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 3551

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 3552 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3600

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 3601 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 3646



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 3366 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3420

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 3421 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 3477

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 3478 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3528

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 3529 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 3574

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 3575 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3623

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 3624 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 3669



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 3389 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3443

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 3444 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 3500

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 3501 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3551

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 3552 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 3597

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 3598 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3646

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 3647 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 3692



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 3412 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3466

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 3467 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 3523

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 3524 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3574

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 3575 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 3620

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 3621 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3669

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 3670 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 3715



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 3435 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3489

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 3490 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 3546

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 3547 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3597

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 3598 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 3643

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 3644 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3692

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 3693 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 3738



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 3458 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3512

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 3513 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 3569

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 3570 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3620

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 3621 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 3666

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 3667 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3715

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 3716 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 3761



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 3481 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3535

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 3536 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 3592

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 3593 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3643

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 3644 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 3689

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 3690 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3738

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 3739 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 3784



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 3504 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3558

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 3559 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 3615

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 3616 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3666

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 3667 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 3712

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 3713 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3761

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 3762 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 3807



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 3527 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3581

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 3582 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 3638

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 3639 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3689

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 3690 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 3735

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 3736 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3784

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 3785 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 3830



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 3550 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3604

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 3605 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 3661

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 3662 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3712

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 3713 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 3758

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 3759 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3807

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 3808 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 3853



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 3573 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3627

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 3628 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 3684

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 3685 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3735

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 3736 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 3781

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 3782 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3830

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 3831 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 3876



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 3596 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3650

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 3651 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 3707

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 3708 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3758

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 3759 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 3804

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 3805 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3853

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 3854 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 3899



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 71/350 (20%), Positives = 117/350 (33%), Gaps = 64/350 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPP-- 179
            Q P + P     T    P     Q     TP + P    +++     P+  Q P+  P  
Sbjct: 3619 QTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3673

Query: 180  ------PPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSI 230
                  P P+       +T PIT T +      P+G   P    I          +P   
Sbjct: 3674 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--- 3730

Query: 231  YIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI 287
                     +G QTP +TP  ++      P P  +Q P               +P   Q 
Sbjct: 3731 ---------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3781

Query: 288  PQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
            P +   +   +  P+P  +                 +P+TTP        P+    G+ +
Sbjct: 3782 PTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQT 3827

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTAT 403
                P T ++           TV P+  P      + +PI+      P+P    +    T
Sbjct: 3828 PTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3876

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            TP +++ +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 3877 TPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 3922



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 69/334 (20%), Positives = 113/334 (33%), Gaps = 60/334 (17%)

Query: 139  PFFMNEQNRSAATPPSQPPQQPSSMQTGM-NPSAMQGPSPPP--------PPPSYMHIPR 189
            P  M        TPP+  P   ++  T    P+  Q P+  P        P P+      
Sbjct: 1882 PTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 1941

Query: 190  YSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNLYGSPGSIYIRQTSQSSSGRQTPQ 246
             +T PIT T +      P+G   P    I          +P            +G QTP 
Sbjct: 1942 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP------------TGTQTPT 1989

Query: 247  STPWQSSPQ---GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQIPQSAYHSPPPSQCPSP 303
            +TP  ++      P P  +Q P               +P   Q P +   +   +  P+P
Sbjct: 1990 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2049

Query: 304  FSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHSVAYLPYTASSLSKGSM 363
              +                 +P+TTP        P+    G+ +    P T ++      
Sbjct: 2050 TPTGTQ--------------TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT------ 2089

Query: 364  KKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLYTATTPPSSSPSRGISSQPK 419
                 TV P+  P      + +PI+      P+P    +    TTP +++ +  ++  P 
Sbjct: 2090 -----TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--VTPTPT 2142

Query: 420  PPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            P  +  P     T  T  + TP+P+P     PTT
Sbjct: 2143 PTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 2174



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 28/74 (37%), Positives = 37/74 (50%), Gaps = 6/74 (8%)

Query: 383  SPSPISNQPSPWNQHSLYTATTPPSSSPSRGISSQPKPPFSVNP-VYITYTQPTGPSCTP 441
            +PSP +  PSP       T T PP+++PS   ++   PP +  P   IT T    P+ TP
Sbjct: 1398 TPSPPTTTPSP---PPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTP 1454

Query: 442  SP--SPRVIPNPTT 453
            SP  S    P PTT
Sbjct: 1455 SPPISTTTTPPPTT 1468



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 72/354 (20%), Positives = 113/354 (31%), Gaps = 83/354 (23%)

Query: 151  TPPSQPPQQPSSMQTGMNPSAMQGPSPPPPPPSYMHIPRYSTNPITVTVSQNLPSGQTVP 210
            T P  PP   +++     PS     +  PPP +    P  +T    +T +   P   T  
Sbjct: 1623 TTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPS 1682

Query: 211  RALQILPQIPSNLYGSPGSIYIRQTSQSSSGRQTPQSTPWQSSPQGPVPHYSQRPLPVYP 270
              +   P  P+    +P        + + S   T  +TP  ++   P P     P P   
Sbjct: 1683 SPITTTPSPPTTTMTTP------SPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSP--- 1733

Query: 271  HQQNYQPSQYSPKQQQIPQSAYHSP------PPSQCPSPFSSPQHQVQPSQLGHIFMPPS 324
                  PS  +     +P +   SP      PPS  P  FS                 P 
Sbjct: 1734 ---TTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFS-----------------PF 1773

Query: 325  PSTTPPHP----------YQQGPPSYQKQGSHS-----------VAYLPYTASSLSKGSM 363
             +TTP  P             G P++ K G  +            A +   A+      +
Sbjct: 1774 STTTPTTPCVPLCNWTGWLDSGKPNFHKPGGDTELIGDVCGPGWAANISCRATMYPDVPI 1833

Query: 364  KKIEITV-----------EPSQRPGTA----------INRSPSPISNQPSPWNQHSLYTA 402
             ++  TV              Q+PG            IN        QP+     +    
Sbjct: 1834 GQLGQTVVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTEN- 1892

Query: 403  TTPPSSSP---SRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
             TPP+++P   +  ++  P P  +  P     T  T  + TP+P+P     PTT
Sbjct: 1893 PTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTT 1944



 Score = 37.7 bits (86), Expect = 0.037
 Identities = 63/305 (20%), Positives = 106/305 (34%), Gaps = 67/305 (21%)

Query: 159  QPSSMQTGMNPSAMQGPSPPPPPPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQI 215
            QP++M T    +  + P+PP            +T PIT T +      P+G   P    I
Sbjct: 1881 QPTTMTT----TTTENPTPP------------TTTPITTTTTVTPTPTPTGTQTPTTTPI 1924

Query: 216  LPQIPSNLYGSPGSIYIRQTSQSSSGRQTPQSTPWQSSPQ---GPVPHYSQRPLPVYPHQ 272
                      +P            +G QTP +TP  ++      P P  +Q P       
Sbjct: 1925 TTTTTVTPTPTP------------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 1972

Query: 273  QNYQPSQYSPKQQQIPQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHP 332
                    +P   Q P +   +   +  P+P  +                 +P+TTP   
Sbjct: 1973 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ--------------TPTTTPITT 2018

Query: 333  YQQGPPSYQKQGSHSVAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ-- 390
                 P+    G+ +    P T ++           TV P+  P      + +PI+    
Sbjct: 2019 TTTVTPTPTPTGTQTPTTTPITTTT-----------TVTPTPTPTGTQTPTTTPITTTTT 2067

Query: 391  --PSPWNQHSLYTATTPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVI 448
              P+P    +    TTP +++ +  ++  P P  +  P     T  T  + TP+P+P   
Sbjct: 2068 VTPTPTPTGTQTPTTTPITTTTT--VTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGT 2123

Query: 449  PNPTT 453
              PTT
Sbjct: 2124 QTPTT 2128



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 23/74 (31%), Positives = 32/74 (43%), Gaps = 3/74 (4%)

Query: 394  WNQHSLYTATTPPSSSPSRGISSQPKPPFSVNPVYITYTQPT-GPSCTPSP--SPRVIPN 450
            W      T  +PP+++PS   +S    P +  P   T T  T  P+ TPSP  +    P 
Sbjct: 1390 WPMDKCITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPP 1449

Query: 451  PTTVFKITVGRATT 464
            PTT     +   TT
Sbjct: 1450 PTTTPSPPISTTTT 1463


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 70.1 bits (170), Expect = 7e-12
 Identities = 101/404 (25%), Positives = 148/404 (36%), Gaps = 44/404 (10%)

Query: 60  SPDDNRMNRNRLLHINLGIHSPS-SYHPGDGAQLNGGRTLVHSSSD-GHIDPQHAAGKQL 117
           +P      R+R     +G+  P+ S  P    +  G R  V S+S+    +P  AA ++ 
Sbjct: 171 TPSPAMARRSRAAGTEVGLPRPAPSARPRPPTE--GPRKSVSSASEHSTTEPSPAARRRP 228

Query: 118 ICL--VQEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGP 175
                +Q P S     +ATP  +P       R     P+ P Q          P  +Q  
Sbjct: 229 SAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQP--------KPKGLQAL 280

Query: 176 SPPPPPPSYMHIPRYSTNPITVTVSQNLPSGQTVPRALQILPQIPSNLYGSPGSIYIRQT 235
            PP   P     PR    P    +S +  +  +   ALQ   Q P  L  +P        
Sbjct: 281 RPPQVTP-----PRKDAAPALGPLSSSPLATPSPSAALQ--SQAPPTLPATP-------- 325

Query: 236 SQSSSGRQTPQSTPWQSSPQGPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQIPQSAYHSP 295
              SS      +TP   +P  P    S + LP  P      PSQ +         A HS 
Sbjct: 326 --HSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPAT---PPSQATTSLGSPTLQATHSF 380

Query: 296 PPSQCPSPFSSPQHQVQPS-QLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHSVAYLPYT 354
            PS   SP ++P  Q  P+  L  +  PPSP  +PP       PS Q   + +V  L   
Sbjct: 381 LPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLS-PLATPSPQAPNALAVHLL--- 436

Query: 355 ASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQPSPWNQHSLYTATTPPSS---SPS 411
            +  S      ++    P   P   ++ S +P S  P       L    +PP+S   SPS
Sbjct: 437 QAPFSPPPSPPVQAPFSPPASP--PVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPS 494

Query: 412 RGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTTVF 455
                Q  PP +  P+ +    P  P    +P  + +P+P   F
Sbjct: 495 ATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASF 538



 Score = 68.6 bits (166), Expect = 2e-11
 Identities = 103/369 (27%), Positives = 132/369 (35%), Gaps = 41/369 (11%)

Query: 127 APAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPPPPPSYMH 186
           AP  + ATP+ +             PPS  P  P S+QT         PSPP  PPS   
Sbjct: 317 APPTLPATPHSSSLTCQLATPLPLAPPS--PSAPPSLQTL--------PSPPATPPSQAT 366

Query: 187 IPRYSTNPITVTVSQNLPSGQTVPRALQILPQIPSNLYGSPGSIYIRQTSQSSSGRQTPQ 246
               S  P        LPS    P A    PQ P  L   P        S  +S   +P 
Sbjct: 367 TSLGS--PTLQATHSFLPSPPLSPLATPP-PQAPPALALPPLQA---PPSPPASPPLSPL 420

Query: 247 STPWQSSPQGPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQIPQSAYHSPPPSQCPSPFSS 306
           +TP   +P     H  Q P    P      P  +SP     P  +  + PPSQ P   ++
Sbjct: 421 ATPSPQAPNALAVHLLQAPFSPPPSPPVQAP--FSPPAS--PPVSPSATPPSQAPPSLAA 476

Query: 307 PQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHSVAYLPYTASSLSKGSMKKI 366
           P  QV PS       P SPS TPP    Q PP             P    +L+   ++  
Sbjct: 477 PPLQVPPSPPAS--PPMSPSATPP---PQAPPPLAAPPLQLAKPPPQAPPALATPPLQ-- 529

Query: 367 EITVEPSQRPGTAINRSPS---PISNQPSPWNQHSLYTAT----TPPSSSPSRGISSQPK 419
            +   P+  PG A   SPS   P+S   +P  Q     A      PPS   S  + +  +
Sbjct: 530 ALPSPPASFPGQA-PFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRR 588

Query: 420 PP-----FSVNPVYITYTQPTGPSCTPSPSP-RVIPNPTTVFKITVGRATTENLLNLVDQ 473
           PP      SV+   +T     GP   PS SP   +  P      +   +T E L      
Sbjct: 589 PPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSG 648

Query: 474 EERSAAPEP 482
            E  AA  P
Sbjct: 649 PEGGAAASP 657



 Score = 53.9 bits (128), Expect = 5e-07
 Identities = 82/352 (23%), Positives = 120/352 (34%), Gaps = 67/352 (19%)

Query: 145 QNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPPPPPSYMHIPRYSTNPITV-TVSQNL 203
           ++ S  TP +  P      +       +  P+P   P      PR S +  +  + ++  
Sbjct: 162 RDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPS 221

Query: 204 PSGQTVPRALQILPQIPSNLYGSPGSIYIRQTSQSSSGRQTPQSTPWQSSPQG------- 256
           P+ +  P A               G    R  S+S S   TP S+P +S P         
Sbjct: 222 PAARRRPSA---------------GGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAP 266

Query: 257 -----PVPHYSQ--RPLPVYPHQQNYQPS----QYSPKQQQIPQSAYHSPPPSQCP-SPF 304
                P P   Q  RP  V P +++  P+      SP     P +A  S  P   P +P 
Sbjct: 267 AHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPH 326

Query: 305 SS----------PQHQVQPSQLGHIFMPPSPSTTPP---------------HPYQQGPP- 338
           SS          P     PS    +   PSP  TPP               H +   PP 
Sbjct: 327 SSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPL 386

Query: 339 ----SYQKQGSHSVAYLPYTASSLSKGSMKKIEITVEPSQRPGT-AINRSPSPISNQPSP 393
               +   Q   ++A  P  A      S     +     Q P   A++   +P S  PSP
Sbjct: 387 SPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSP 446

Query: 394 WNQHSLYTATTPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSP 445
             Q       +PP  SPS    SQ  P  +  P+ +  + P  P  +PS +P
Sbjct: 447 PVQAPFSPPASPP-VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATP 497



 Score = 30.0 bits (66), Expect = 7.8
 Identities = 68/298 (22%), Positives = 96/298 (32%), Gaps = 82/298 (27%)

Query: 121 VQEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPPP 180
           +Q P S PA    +P+  P            P + PP     +Q            PPP 
Sbjct: 479 LQVPPSPPASPPMSPSATP-----------PPQAPPPLAAPPLQLA---------KPPPQ 518

Query: 181 PPSYMHIPRYSTNPITVTVSQNLPSGQTVPRALQILPQIPSNLYGSPGSIYIRQTSQSSS 240
            P     P  +T P                  LQ LP  P++  G          S S+S
Sbjct: 519 AP-----PALATPP------------------LQALPSPPASFPGQ------APFSPSAS 549

Query: 241 GRQTPQSTPWQSSPQGPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQI--PQSAYHSP--- 295
              +P +TP    PQ   P     PL   P      P+  +P++     P ++   P   
Sbjct: 550 LPMSPLATP---PPQ--APPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLT 604

Query: 296 ---PPSQCPSPFSSPQHQVQ-PSQLGHIFMPPSPSTTPP--HPYQQG---------PPSY 340
               P   P P  SP   +  P   GH     S ++TP     Y  G         PP  
Sbjct: 605 LALAPGPPPPPSRSPSSTLSGPDLAGH---SSSATSTPEELRGYDSGPEGGAAASPPPDA 661

Query: 341 QKQGSHSVAYLPYTASSLSKGSMKKIEITVEPSQRPGTA-----INRSPSPISNQPSP 393
           +    H  A+    A  L+        +   P+  PG+A     I  +  P S  P+P
Sbjct: 662 ELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAP 719


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 68.9 bits (167), Expect = 2e-11
 Identities = 88/314 (28%), Positives = 121/314 (38%), Gaps = 54/314 (17%)

Query: 126 SAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGM--NPSAMQGPSPPP---P 180
           S P +   TP   P       +S   P ++PP QPS +   +   P  ++ P  PP    
Sbjct: 302 SKPPIQQPTPGKPPAQQPGHEKSQPGP-AKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTK 360

Query: 181 PPSYMHIPRYSTNPITVTVSQNLPSGQTVPRALQILPQIPSNLYGSPGSIYIRQTSQSSS 240
           PP+    P  +  P   T S+   S Q  P+AL   P +       PG      T Q  +
Sbjct: 361 PPAQPLGP--AKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAK-PPTQQVGT 417

Query: 241 GRQTPQSTPWQSSPQGPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQIPQSAYHSPPPSQC 300
            +   Q    QS  + P P  +    PV        P+Q +   +   Q    + PPSQ 
Sbjct: 418 PKPLAQQPGLQSPAKAPGPTKT----PVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQL 473

Query: 301 PSPFSSPQHQVQPS----QLGHIFMPPS--PSTTPPHPYQQGP--PSYQKQGSHSVAYLP 352
           P P   P  Q  P+    Q      PPS  P +T P P Q GP  PS Q+ GS       
Sbjct: 474 PGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGS------- 526

Query: 353 YTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQPSPWNQHSLYTATTPPSSSPSR 412
                           T  PSQ+PG+A      P + QPSP  + S   +T P S +   
Sbjct: 527 ----------------TKPPSQQPGSA-----KPSAQQPSP-AKPSAQQSTKPVSQTG-- 562

Query: 413 GISSQPKPPFSVNP 426
             S +P  P +V+P
Sbjct: 563 --SGKPLQPPTVSP 574



 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 97/354 (27%), Positives = 126/354 (35%), Gaps = 61/354 (17%)

Query: 148 SAATPPSQPPQ--QPSSMQTGMNPSAMQGPSPPPPPPSYMHIPRYSTNPITVTVSQNLPS 205
           S + PP Q P   +P + Q G   S   GP+ PP  PS +  P  +  P TV      P 
Sbjct: 300 SPSKPPIQQPTPGKPPAQQPGHEKS-QPGPAKPPAQPSGLTKP-LAQQPGTVKPPVQ-PP 356

Query: 206 GQTVPRALQILPQIPSNLYGSPGSIYIRQT-SQSSSGRQTPQSTPWQSSPQGPVPHYSQR 264
           G T P A  + P  P            +QT S+  S  Q       Q    G  P  +Q+
Sbjct: 357 GTTKPPAQPLGPAKPP----------AQQTGSEKPSSEQPGPKALAQPPGVGKTP--AQQ 404

Query: 265 PLPVYPHQQNY---QPSQYSPKQQQIPQSAYHSPPPSQCPSPFSSPQHQVQP----SQLG 317
           P P  P  Q     +P    P  Q   ++   +  P Q P P   P  Q  P    +Q  
Sbjct: 405 PGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQT 464

Query: 318 HIFMPPS--PSTTPPHPYQQGPPSYQKQGSHSVAYLPYTASSLSKGSMKKIEITVEPSQR 375
               PPS  P    P P Q GP     Q                 GS K       PSQ+
Sbjct: 465 GPTKPPSQLPGPAKPPPQQPGPAKPPPQ---------------QPGSAKP------PSQQ 503

Query: 376 PGTAINRSPSPISNQPSPWNQHSLYTATT-PPSSSP--SRGISSQPKP-----PFSVNPV 427
           PG     S  P   QP P         +T PPS  P  ++  + QP P       S  PV
Sbjct: 504 PG-----STKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPV 558

Query: 428 YITYTQPTGPSCTPSPSPRVIPNPTTVFKITVGRATTENLLNLVDQEERSAAPE 481
             T +       T SPS +  P+      I     TTE LL++ ++   +   E
Sbjct: 559 SQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTE 612



 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 82/354 (23%), Positives = 125/354 (35%), Gaps = 67/354 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPPPP 181
            Q P  +P+V +      PFF +     +A PP  PP  P        P     P PPPPP
Sbjct: 2375 QLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPP--------PPPPPPPPPPPPP 2426

Query: 182  ------PSYMHIPRYS---TNPIT----------------VTVSQNLPSGQTVPRALQIL 216
                  P    +P+      +P+T                V  S  LP  +    A   +
Sbjct: 2427 LPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPV 2486

Query: 217  PQIPSNLYGSPGSIYIRQTSQSSSGRQTPQSTPWQSSPQGPVPHYSQRPLPVYPHQQNYQ 276
            P  PS++    G ++  +   S      P   P    PQ  +P  +Q+P  ++P      
Sbjct: 2487 PPKPSSI--PSGLVFTHRPEPSK-----PPIAPKPVIPQ--LPTTTQKPTDIHPKPTGLS 2537

Query: 277  PSQYSPKQQQIPQSAYHSPPPSQCPSPF---SSPQHQVQPSQLGHIFMPPSPSTTPPHPY 333
             +  S     +  + Y  P P+   SP    SSP+     ++   +   PS   TP    
Sbjct: 2538 LTS-SMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPT--- 2593

Query: 334  QQGPPSYQKQGSHSVAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQPSP 393
                       S ++   P        GS  K  ++VEP       +     PIS++ + 
Sbjct: 2594 -------DSSASQAITSWPL-------GSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTF 2639

Query: 394  WNQHSLYTATTPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRV 447
            +   +L T +  P ++P    SS    P SV     T    T  S T S +P V
Sbjct: 2640 YISGALQTFSATPVTAP----SSFQAAPTSVTQFLTTEVSKTEVSATRSTAPSV 2689



 Score = 46.6 bits (109), Expect = 8e-05
 Identities = 73/299 (24%), Positives = 100/299 (33%), Gaps = 62/299 (20%)

Query: 225 GSPGSIYIRQTSQSSS-----GR--QTPQSTPWQSSPQGPVPHYSQRPLPVYP---HQQN 274
           G+P SI  +Q  +  S     G+  Q P  TP     + P+   + RP          ++
Sbjct: 234 GTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGES 293

Query: 275 YQPSQYSPKQQQIPQSAYHSPP---------------PSQCPSPFSSPQHQVQPSQLGHI 319
            +PS  SP +  I Q     PP               P   PS  + P  Q QP  +   
Sbjct: 294 VKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQ-QPGTVKPP 352

Query: 320 FMPPSPSTTPPHPYQQGPPSYQKQGSHSVAYLPYTASSLSKGSMKKIEITVEPSQRPG-- 377
             PP  +  P  P     P  Q+ GS      P +     K   +   +   P+Q+PG  
Sbjct: 353 VQPPGTTKPPAQPLGPAKPPAQQTGSEK----PSSEQPGPKALAQPPGVGKTPAQQPGPA 408

Query: 378 ---TAINRSPSPISNQPSPWNQHSLYTATTPPSSSPSRG-ISSQPKPPFSVNPVYITYTQ 433
              T    +P P++ QP   +       T  P   P  G I +Q   P        T  Q
Sbjct: 409 KPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGK------TSAQ 462

Query: 434 PTGPSCTPSPSPRVIPNPTTVFKITVGRATTENLLNLVDQEERSAAPEPIQPISVIPGS 492
            TGP+  PS  P     P                     Q+   A P P QP S  P S
Sbjct: 463 QTGPTKPPSQLPGPAKPP--------------------PQQPGPAKPPPQQPGSAKPPS 501



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 55/226 (24%), Positives = 84/226 (37%), Gaps = 41/226 (18%)

Query: 143  NEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGP----SPPPPPP-----SYMHIPRYSTN 193
            +E        P Q  ++P   QT M+P     P    SP PP P       +  P+ S  
Sbjct: 838  SESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPK 897

Query: 194  PITVT--VSQNLPSGQTVPRALQILPQ--IPSNLYGSPGSIYIRQTSQ-SSSGRQTPQST 248
            P   +   S NL S    P++    PQ  +   L+G   SI+ + ++  S++G+  P S 
Sbjct: 898  PQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQ 957

Query: 249  PWQSSPQGPVPHYSQRP-------------------LPVYPHQQNYQPSQYSPKQQQIP- 288
                +P    P  SQ P                   +PV    +     +  PK +Q P 
Sbjct: 958  SGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPT 1017

Query: 289  ----QSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPP 330
                ++    PP     S  + PQ  V P++L      P P +T P
Sbjct: 1018 VKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLE---KSPKPESTCP 1060



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 82/375 (21%), Positives = 116/375 (30%), Gaps = 69/375 (18%)

Query: 143 NEQNRSAATPPSQP------PQQPSS-----MQTGMNPSAMQGPSPPPPPPSYMHIPRYS 191
           ++Q  S   PP QP      PQQP S      Q G    + Q PSP  P       P   
Sbjct: 501 SQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQ 560

Query: 192 TN------PITVTVSQNLPSGQTVPRALQILPQIPSNLYGSPGSIYIRQTSQSSSG---- 241
           T       P TV+ S   P  Q +P+ +  L      L   P        ++  +     
Sbjct: 561 TGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSL 620

Query: 242 ---RQTPQSTPWQS-------------SPQGPVPHYSQRPLPVYP-------HQQNYQPS 278
                 P  T  +                  PVP   Q  L   P        + + QP 
Sbjct: 621 CGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQ 680

Query: 279 QYSPKQQQIPQSAYHSPPPSQCPSPF-------SSPQHQVQPSQLGHIFMPPSPSTTPPH 331
           Q SPK+   P+      P  + P P         SP  + +          P+P   P  
Sbjct: 681 QTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSV 740

Query: 332 PYQQG---------------PPSYQKQGSHSVAYLPYTASSLSKGSMKKIEITVEPSQRP 376
           P +Q                 P+     S S    P   S  SK   +  E T  P +  
Sbjct: 741 PSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPS--SKVQSQAEEKTTPPLKTD 798

Query: 377 GTAINRSPSPISNQPSPWNQHSLYTATTPPSSSPSRGISSQPKPPFSVNPVYITYTQPTG 436
               ++S  P   + SP++  ++    +        G SS+ K    V+PV     +P  
Sbjct: 799 SAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQ-KKEEPKK 857

Query: 437 PSCTPSPSPRVIPNP 451
                SP P   P P
Sbjct: 858 AQTKMSPKPDAKPMP 872



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 66/308 (21%), Positives = 99/308 (32%), Gaps = 33/308 (10%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQ--TGMNPSAMQGPSPPP 179
            ++P  A ++    P   P   +EQ+++        P+QP  ++  T +  S+     P  
Sbjct: 721  KQPPEADSLSKPAPPKEPSVPSEQDKAPVA--DDKPKQPKMVKPTTDLVSSSSATTKPDI 778

Query: 180  PPPSYMHIPRYSTNPITVTVSQNLPSGQTVPRALQILPQIPSNLYGSPGSI--YIRQTSQ 237
            P           T P   T S   PS    P   ++ P   S     P S    I     
Sbjct: 779  PSSKVQSQAEEKTTPPLKTDSAK-PSQSFPPTGEKVSP-FDSKAIPRPASDSKIISHPGP 836

Query: 238  SSSGRQTPQSTPWQSSPQGPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQIPQSAYHSPPP 297
            SS  +   Q  P Q   +         P P         P+   P+    P +    P P
Sbjct: 837  SSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPR----PTAGQTVPTP 892

Query: 298  SQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHSVAYLPYTASS 357
             Q P P    Q +     LG I   P    T P     G                + AS 
Sbjct: 893  QQSPKP--QEQSRRFSLNLGSITDAPKSQPTTPQETVTGK------------LFGFGASI 938

Query: 358  LSKGSMKKIEITVEPSQR----PGTAINRSPSPISNQPSPWNQHSLYTATTPPSSSPSRG 413
             S+ S   I    +P       PG  + ++P+P  +QP         T   PP+ + S  
Sbjct: 939  FSQAS-NLISTAGQPGPHSQSGPGAPMKQAPAP--SQPPTSQGPPKSTGQAPPAPAKSIP 995

Query: 414  ISSQPKPP 421
            +  + K P
Sbjct: 996  VKKETKAP 1003



 Score = 30.8 bits (68), Expect = 4.5
 Identities = 42/174 (24%), Positives = 59/174 (33%), Gaps = 42/174 (24%)

Query: 334  QQGPPSYQKQGSHSVAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQPSP 393
            Q+ P S    GS SV+ LP       + S   ++I+ +P   P       P P    P P
Sbjct: 2369 QEKPASQLPSGSPSVSSLPAKPRPFFRSS--SLDISAQPPPPPPPPPPPPPPPPPPPPPP 2426

Query: 394  WNQHSLYTATTPPSSSPSRGISSQPK-----PPFSVNPVYITYTQ------------PTG 436
                       PP +SP   I  + K     P  +  P++   T             P  
Sbjct: 2427 ----------LPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVT 2476

Query: 437  PSCTPSPSPRVIPNPTTVFKITVGRATTENLLNLVDQEERSAAPEPIQPISVIP 490
              CT +P P V P P+++               LV       +  PI P  VIP
Sbjct: 2477 RICTTAPPP-VPPKPSSIPS------------GLVFTHRPEPSKPPIAPKPVIP 2517



 Score = 30.4 bits (67), Expect = 5.9
 Identities = 23/93 (24%), Positives = 39/93 (41%), Gaps = 6/93 (6%)

Query: 289  QSAYHSPPPSQCPS------PFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQK 342
            QS+  SP PS   S      P  S   QV   +  H     S S++  H    GP   Q 
Sbjct: 4841 QSSQQSPKPSVIKSRSHGIFPDPSKDMQVPTIEKSHSSPGSSKSSSEGHLRSHGPSRSQS 4900

Query: 343  QGSHSVAYLPYTASSLSKGSMKKIEITVEPSQR 375
            + S +  +L    ++++       ++ ++PS+R
Sbjct: 4901 KTSVTQTHLEDAGAAIAAAEAAVQQLRIQPSKR 4933


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 68.9 bits (167), Expect = 2e-11
 Identities = 88/314 (28%), Positives = 121/314 (38%), Gaps = 54/314 (17%)

Query: 126 SAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGM--NPSAMQGPSPPP---P 180
           S P +   TP   P       +S   P ++PP QPS +   +   P  ++ P  PP    
Sbjct: 302 SKPPIQQPTPGKPPAQQPGHEKSQPGP-AKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTK 360

Query: 181 PPSYMHIPRYSTNPITVTVSQNLPSGQTVPRALQILPQIPSNLYGSPGSIYIRQTSQSSS 240
           PP+    P  +  P   T S+   S Q  P+AL   P +       PG      T Q  +
Sbjct: 361 PPAQPLGP--AKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAK-PPTQQVGT 417

Query: 241 GRQTPQSTPWQSSPQGPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQIPQSAYHSPPPSQC 300
            +   Q    QS  + P P  +    PV        P+Q +   +   Q    + PPSQ 
Sbjct: 418 PKPLAQQPGLQSPAKAPGPTKT----PVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQL 473

Query: 301 PSPFSSPQHQVQPS----QLGHIFMPPS--PSTTPPHPYQQGP--PSYQKQGSHSVAYLP 352
           P P   P  Q  P+    Q      PPS  P +T P P Q GP  PS Q+ GS       
Sbjct: 474 PGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGS------- 526

Query: 353 YTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQPSPWNQHSLYTATTPPSSSPSR 412
                           T  PSQ+PG+A      P + QPSP  + S   +T P S +   
Sbjct: 527 ----------------TKPPSQQPGSA-----KPSAQQPSP-AKPSAQQSTKPVSQTG-- 562

Query: 413 GISSQPKPPFSVNP 426
             S +P  P +V+P
Sbjct: 563 --SGKPLQPPTVSP 574



 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 97/354 (27%), Positives = 126/354 (35%), Gaps = 61/354 (17%)

Query: 148 SAATPPSQPPQ--QPSSMQTGMNPSAMQGPSPPPPPPSYMHIPRYSTNPITVTVSQNLPS 205
           S + PP Q P   +P + Q G   S   GP+ PP  PS +  P  +  P TV      P 
Sbjct: 300 SPSKPPIQQPTPGKPPAQQPGHEKS-QPGPAKPPAQPSGLTKP-LAQQPGTVKPPVQ-PP 356

Query: 206 GQTVPRALQILPQIPSNLYGSPGSIYIRQT-SQSSSGRQTPQSTPWQSSPQGPVPHYSQR 264
           G T P A  + P  P            +QT S+  S  Q       Q    G  P  +Q+
Sbjct: 357 GTTKPPAQPLGPAKPP----------AQQTGSEKPSSEQPGPKALAQPPGVGKTP--AQQ 404

Query: 265 PLPVYPHQQNY---QPSQYSPKQQQIPQSAYHSPPPSQCPSPFSSPQHQVQP----SQLG 317
           P P  P  Q     +P    P  Q   ++   +  P Q P P   P  Q  P    +Q  
Sbjct: 405 PGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQT 464

Query: 318 HIFMPPS--PSTTPPHPYQQGPPSYQKQGSHSVAYLPYTASSLSKGSMKKIEITVEPSQR 375
               PPS  P    P P Q GP     Q                 GS K       PSQ+
Sbjct: 465 GPTKPPSQLPGPAKPPPQQPGPAKPPPQ---------------QPGSAKP------PSQQ 503

Query: 376 PGTAINRSPSPISNQPSPWNQHSLYTATT-PPSSSP--SRGISSQPKP-----PFSVNPV 427
           PG     S  P   QP P         +T PPS  P  ++  + QP P       S  PV
Sbjct: 504 PG-----STKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPV 558

Query: 428 YITYTQPTGPSCTPSPSPRVIPNPTTVFKITVGRATTENLLNLVDQEERSAAPE 481
             T +       T SPS +  P+      I     TTE LL++ ++   +   E
Sbjct: 559 SQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTE 612



 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 82/354 (23%), Positives = 125/354 (35%), Gaps = 67/354 (18%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPPPP 181
            Q P  +P+V +      PFF +     +A PP  PP  P        P     P PPPPP
Sbjct: 2375 QLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPP--------PPPPPPPPPPPPP 2426

Query: 182  ------PSYMHIPRYS---TNPIT----------------VTVSQNLPSGQTVPRALQIL 216
                  P    +P+      +P+T                V  S  LP  +    A   +
Sbjct: 2427 LPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPV 2486

Query: 217  PQIPSNLYGSPGSIYIRQTSQSSSGRQTPQSTPWQSSPQGPVPHYSQRPLPVYPHQQNYQ 276
            P  PS++    G ++  +   S      P   P    PQ  +P  +Q+P  ++P      
Sbjct: 2487 PPKPSSI--PSGLVFTHRPEPSK-----PPIAPKPVIPQ--LPTTTQKPTDIHPKPTGLS 2537

Query: 277  PSQYSPKQQQIPQSAYHSPPPSQCPSPF---SSPQHQVQPSQLGHIFMPPSPSTTPPHPY 333
             +  S     +  + Y  P P+   SP    SSP+     ++   +   PS   TP    
Sbjct: 2538 LTS-SMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPT--- 2593

Query: 334  QQGPPSYQKQGSHSVAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQPSP 393
                       S ++   P        GS  K  ++VEP       +     PIS++ + 
Sbjct: 2594 -------DSSASQAITSWPL-------GSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTF 2639

Query: 394  WNQHSLYTATTPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRV 447
            +   +L T +  P ++P    SS    P SV     T    T  S T S +P V
Sbjct: 2640 YISGALQTFSATPVTAP----SSFQAAPTSVTQFLTTEVSKTEVSATRSTAPSV 2689



 Score = 46.6 bits (109), Expect = 8e-05
 Identities = 73/299 (24%), Positives = 100/299 (33%), Gaps = 62/299 (20%)

Query: 225 GSPGSIYIRQTSQSSS-----GR--QTPQSTPWQSSPQGPVPHYSQRPLPVYP---HQQN 274
           G+P SI  +Q  +  S     G+  Q P  TP     + P+   + RP          ++
Sbjct: 234 GTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGES 293

Query: 275 YQPSQYSPKQQQIPQSAYHSPP---------------PSQCPSPFSSPQHQVQPSQLGHI 319
            +PS  SP +  I Q     PP               P   PS  + P  Q QP  +   
Sbjct: 294 VKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQ-QPGTVKPP 352

Query: 320 FMPPSPSTTPPHPYQQGPPSYQKQGSHSVAYLPYTASSLSKGSMKKIEITVEPSQRPG-- 377
             PP  +  P  P     P  Q+ GS      P +     K   +   +   P+Q+PG  
Sbjct: 353 VQPPGTTKPPAQPLGPAKPPAQQTGSEK----PSSEQPGPKALAQPPGVGKTPAQQPGPA 408

Query: 378 ---TAINRSPSPISNQPSPWNQHSLYTATTPPSSSPSRG-ISSQPKPPFSVNPVYITYTQ 433
              T    +P P++ QP   +       T  P   P  G I +Q   P        T  Q
Sbjct: 409 KPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGK------TSAQ 462

Query: 434 PTGPSCTPSPSPRVIPNPTTVFKITVGRATTENLLNLVDQEERSAAPEPIQPISVIPGS 492
            TGP+  PS  P     P                     Q+   A P P QP S  P S
Sbjct: 463 QTGPTKPPSQLPGPAKPP--------------------PQQPGPAKPPPQQPGSAKPPS 501



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 55/226 (24%), Positives = 84/226 (37%), Gaps = 41/226 (18%)

Query: 143  NEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGP----SPPPPPP-----SYMHIPRYSTN 193
            +E        P Q  ++P   QT M+P     P    SP PP P       +  P+ S  
Sbjct: 838  SESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPK 897

Query: 194  PITVT--VSQNLPSGQTVPRALQILPQ--IPSNLYGSPGSIYIRQTSQ-SSSGRQTPQST 248
            P   +   S NL S    P++    PQ  +   L+G   SI+ + ++  S++G+  P S 
Sbjct: 898  PQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQ 957

Query: 249  PWQSSPQGPVPHYSQRP-------------------LPVYPHQQNYQPSQYSPKQQQIP- 288
                +P    P  SQ P                   +PV    +     +  PK +Q P 
Sbjct: 958  SGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPT 1017

Query: 289  ----QSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPP 330
                ++    PP     S  + PQ  V P++L      P P +T P
Sbjct: 1018 VKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLE---KSPKPESTCP 1060



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 82/375 (21%), Positives = 116/375 (30%), Gaps = 69/375 (18%)

Query: 143 NEQNRSAATPPSQP------PQQPSS-----MQTGMNPSAMQGPSPPPPPPSYMHIPRYS 191
           ++Q  S   PP QP      PQQP S      Q G    + Q PSP  P       P   
Sbjct: 501 SQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQ 560

Query: 192 TN------PITVTVSQNLPSGQTVPRALQILPQIPSNLYGSPGSIYIRQTSQSSSG---- 241
           T       P TV+ S   P  Q +P+ +  L      L   P        ++  +     
Sbjct: 561 TGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSL 620

Query: 242 ---RQTPQSTPWQS-------------SPQGPVPHYSQRPLPVYP-------HQQNYQPS 278
                 P  T  +                  PVP   Q  L   P        + + QP 
Sbjct: 621 CGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQ 680

Query: 279 QYSPKQQQIPQSAYHSPPPSQCPSPF-------SSPQHQVQPSQLGHIFMPPSPSTTPPH 331
           Q SPK+   P+      P  + P P         SP  + +          P+P   P  
Sbjct: 681 QTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSV 740

Query: 332 PYQQG---------------PPSYQKQGSHSVAYLPYTASSLSKGSMKKIEITVEPSQRP 376
           P +Q                 P+     S S    P   S  SK   +  E T  P +  
Sbjct: 741 PSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPS--SKVQSQAEEKTTPPLKTD 798

Query: 377 GTAINRSPSPISNQPSPWNQHSLYTATTPPSSSPSRGISSQPKPPFSVNPVYITYTQPTG 436
               ++S  P   + SP++  ++    +        G SS+ K    V+PV     +P  
Sbjct: 799 SAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQ-KKEEPKK 857

Query: 437 PSCTPSPSPRVIPNP 451
                SP P   P P
Sbjct: 858 AQTKMSPKPDAKPMP 872



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 66/308 (21%), Positives = 99/308 (32%), Gaps = 33/308 (10%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQ--TGMNPSAMQGPSPPP 179
            ++P  A ++    P   P   +EQ+++        P+QP  ++  T +  S+     P  
Sbjct: 721  KQPPEADSLSKPAPPKEPSVPSEQDKAPVA--DDKPKQPKMVKPTTDLVSSSSATTKPDI 778

Query: 180  PPPSYMHIPRYSTNPITVTVSQNLPSGQTVPRALQILPQIPSNLYGSPGSI--YIRQTSQ 237
            P           T P   T S   PS    P   ++ P   S     P S    I     
Sbjct: 779  PSSKVQSQAEEKTTPPLKTDSAK-PSQSFPPTGEKVSP-FDSKAIPRPASDSKIISHPGP 836

Query: 238  SSSGRQTPQSTPWQSSPQGPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQIPQSAYHSPPP 297
            SS  +   Q  P Q   +         P P         P+   P+    P +    P P
Sbjct: 837  SSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPR----PTAGQTVPTP 892

Query: 298  SQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHSVAYLPYTASS 357
             Q P P    Q +     LG I   P    T P     G                + AS 
Sbjct: 893  QQSPKP--QEQSRRFSLNLGSITDAPKSQPTTPQETVTGK------------LFGFGASI 938

Query: 358  LSKGSMKKIEITVEPSQR----PGTAINRSPSPISNQPSPWNQHSLYTATTPPSSSPSRG 413
             S+ S   I    +P       PG  + ++P+P  +QP         T   PP+ + S  
Sbjct: 939  FSQAS-NLISTAGQPGPHSQSGPGAPMKQAPAP--SQPPTSQGPPKSTGQAPPAPAKSIP 995

Query: 414  ISSQPKPP 421
            +  + K P
Sbjct: 996  VKKETKAP 1003



 Score = 31.2 bits (69), Expect = 3.5
 Identities = 34/140 (24%), Positives = 57/140 (40%), Gaps = 12/140 (8%)

Query: 289  QSAYHSPPPSQCPS------PFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQK 342
            QS+  SP PS   S      P  S   QV   +  H     S S++  H    GP   Q 
Sbjct: 4841 QSSQQSPKPSVIKSRSHGIFPDPSKDMQVPTIEKSHSSPGSSKSSSEGHLRSHGPSRSQS 4900

Query: 343  QGSHSVAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSP--SPISNQPSPWNQHSLY 400
            + S +  +L    ++++       ++ ++P++ P    N  P  S +S   S  +  S Y
Sbjct: 4901 KTSVTQTHLEDAGAAIAAAEAAVQQLRIQPTKPP----NHRPAESSVSTGSSGSSFGSGY 4956

Query: 401  TATTPPSSSPSRGISSQPKP 420
            +  +  SSS +   +  P P
Sbjct: 4957 SVDSEGSSSTAGETNLFPIP 4976



 Score = 30.8 bits (68), Expect = 4.5
 Identities = 42/174 (24%), Positives = 59/174 (33%), Gaps = 42/174 (24%)

Query: 334  QQGPPSYQKQGSHSVAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQPSP 393
            Q+ P S    GS SV+ LP       + S   ++I+ +P   P       P P    P P
Sbjct: 2369 QEKPASQLPSGSPSVSSLPAKPRPFFRSS--SLDISAQPPPPPPPPPPPPPPPPPPPPPP 2426

Query: 394  WNQHSLYTATTPPSSSPSRGISSQPK-----PPFSVNPVYITYTQ------------PTG 436
                       PP +SP   I  + K     P  +  P++   T             P  
Sbjct: 2427 ----------LPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVT 2476

Query: 437  PSCTPSPSPRVIPNPTTVFKITVGRATTENLLNLVDQEERSAAPEPIQPISVIP 490
              CT +P P V P P+++               LV       +  PI P  VIP
Sbjct: 2477 RICTTAPPP-VPPKPSSIPS------------GLVFTHRPEPSKPPIAPKPVIP 2517


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 68.9 bits (167), Expect = 2e-11
 Identities = 83/300 (27%), Positives = 113/300 (37%), Gaps = 45/300 (15%)

Query: 151  TPPSQPPQQPSSMQTGMNPSAMQGPSPPPPPPSYMHIPRYSTNPITVTVSQNLPSGQTVP 210
            TPPS       S  T ++P  +  P    P PS +++P     P T       P+ +  P
Sbjct: 857  TPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPAT-------PAPKQAP 909

Query: 211  RALQILPQIPSNLYGSPGSIYIRQTSQSSSGRQTPQSTPWQSSPQG----PVPHYSQRPL 266
             AL +    P     +P    I  +         P +TP   SP+G    P P ++  P 
Sbjct: 910  -ALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATP--PSPKGGPATPSPKWAPTPP 966

Query: 267  PVYPHQQNYQPSQYSPKQQQIPQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPS 326
               P      P+  SPK          +PP +  PSP   P     PS  G    P  P+
Sbjct: 967  AATPPSPKGGPATPSPK-------GAPTPPAATPPSPKGGP---ATPSPKG---APTPPA 1013

Query: 327  TTPPHPYQQGPPS---YQKQGSHSVAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRS 383
             TPP P  +G P+   + K  S   A  P +     KGS      T  P   P T     
Sbjct: 1014 VTPPSP--KGSPAATPFPKGASTPPAATPPS----PKGSP---AATPLPKGAPTTPAATL 1064

Query: 384  PSPISNQPSPWNQHSLYTATTPPSSSP--SRGISSQPKPPFSVNPVYITYTQPTGPSCTP 441
            PSP     +P    SL  A TPP+++P   +G  + P P  +  P   T   P G   TP
Sbjct: 1065 PSPKGGPATP----SLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATP 1120



 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 86/351 (24%), Positives = 124/351 (35%), Gaps = 57/351 (16%)

Query: 124  PHSAPAVVAATPNY------NPFFMNEQNRSAATPPSQ------PPQQPSSMQTGMNPSA 171
            P  AP   AATP         P         A TPPS       P   PSS      PS+
Sbjct: 1306 PKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSS 1365

Query: 172  MQGPSPPPPPPSYMHIPRYSTNPITVTVSQNLPSGQTVPRALQILPQIPSNLYGSPGSIY 231
             +GP+PP   PS+   P  +  P +      +PS +  P +  ++P  P     +P  + 
Sbjct: 1366 KEGPTPPAATPSHKGGP--AMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATP--VT 1421

Query: 232  IRQTSQSSSGRQTP--------QSTPWQSSPQGPVPHYSQRPLPVYPHQQNYQPSQYSPK 283
                +  S G  TP        +  P  S+P+G     S +  P  P       +  SPK
Sbjct: 1422 REGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLP-----AVTPPSPK 1476

Query: 284  QQQIPQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQ 343
            +   P+    S  P + P+  +       P+      +P SP   P  P  +  P     
Sbjct: 1477 EPPAPKQVATSSSPKKAPATPAPMGAPTLPA-----VIPSSPKEVPATPSSRRDP----- 1526

Query: 344  GSHSVAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQPSPWNQHSLYTAT 403
                   +  TA+ LS    KK   T+ P +         PSP      P  + +  T +
Sbjct: 1527 -------IAPTATLLS----KKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPS 1575

Query: 404  TPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTTV 454
            +  +SSP     S  K   S   + I       P    SPSP+  P P  V
Sbjct: 1576 SKEASSPPAVTPSTYKGAPSPKELLI-------PPAVTSPSPKEAPTPPAV 1619



 Score = 61.2 bits (147), Expect = 3e-09
 Identities = 81/349 (23%), Positives = 125/349 (35%), Gaps = 44/349 (12%)

Query: 128  PAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPPPP-----P 182
            PA    +P   P       + A TPP+  P  P       +P     P    PP     P
Sbjct: 966  PAATPPSPKGGP--ATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSP 1023

Query: 183  SYMHIPRYSTNPITVTVS--QNLPSGQTVPRALQILPQ--IPSNLYGSPGSIYIRQTSQS 238
            +    P+ ++ P   T    +  P+   +P+     P   +PS   G          +  
Sbjct: 1024 AATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPP 1083

Query: 239  SSGRQTPQSTPWQSSPQG-PVPHYSQRPLP-----VYPHQQNYQPSQYSPKQQQIPQSAY 292
            ++   +P+  P   SP+G P+P  +  P P       PH+        +P     P+   
Sbjct: 1084 AATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPS---PKGGL 1140

Query: 293  HSPPPSQCPS-PFSSPQHQVQPSQLGHIFMPP------SPSTTPPHPYQQGPPSYQKQGS 345
             +PPP   P+ P ++P     PS  G +  PP      +P+ TPP P + G  +   +G+
Sbjct: 1141 ATPPPKGAPTTPAATP-----PSPKGGLATPPPKGAPTTPAATPPSP-KGGLATPSPKGA 1194

Query: 346  HSVAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQPSPWNQHSLYTATTP 405
             +    P       KG +     T  P   P T     PSP     +P    S   A T 
Sbjct: 1195 PTT---PAATPPSPKGGLA----TPSPKGAPTTPAATPPSPKGGLATP----SPKGAPTT 1243

Query: 406  PSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTTV 454
            P+++P         PP    P     T P+      +P  +  PNP  V
Sbjct: 1244 PAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVV 1292



 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 94/327 (28%), Positives = 123/327 (37%), Gaps = 60/327 (18%)

Query: 126  SAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPPPPPSYM 185
            S+P    ATP       +   + A TPP+  P  PS       PS    P+PP   P   
Sbjct: 916  SSPKKARATPAPKGIPASPSPKGAPTPPAATP--PSPKGGPATPSPKWAPTPPAATP--- 970

Query: 186  HIPRYSTNPITVTVSQNLPSGQTVPRALQILPQIPSNLYGSPGSIYIRQTSQSSSGRQTP 245
              P     P T +     P G   P A       P +  G P        + S  G  TP
Sbjct: 971  --PSPKGGPATPS-----PKGAPTPPA-----ATPPSPKGGP-------ATPSPKGAPTP 1011

Query: 246  QS-TPWQSSPQG-----PVPHYSQRPLPVYPHQQNYQPS-QYSPKQQQIPQSAYHSPPPS 298
             + TP   SP+G     P P  +  P    P      PS + SP    +P+ A  + P +
Sbjct: 1012 PAVTP--PSPKGSPAATPFPKGASTPPAATP------PSPKGSPAATPLPKGA-PTTPAA 1062

Query: 299  QCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHSVAYLPYTASSL 358
              PSP   P     PS  G    P  P+ TPP P + GP +   +G    A +P  A+  
Sbjct: 1063 TLPSPKGGP---ATPSLKG---APTPPAATPPSP-KGGPATPSPKG----APMPPAATPP 1111

Query: 359  S-KGSMKKIEITVEPSQRPGTAINRSPSPISNQPSPWNQHSLYT-ATTPPSSSPSRGISS 416
            S KG +     T      P T     PSP     +P  + +  T A TPP  SP  G+++
Sbjct: 1112 SPKGGL----ATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPP--SPKGGLAT 1165

Query: 417  QPKPPFSVNPVYITYTQPTGPSCTPSP 443
             P       P   T   P G   TPSP
Sbjct: 1166 PPPKGAPTTPA-ATPPSPKGGLATPSP 1191



 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 88/346 (25%), Positives = 123/346 (35%), Gaps = 55/346 (15%)

Query: 124  PHSAPAVVAATPNYNPFFMNEQNRSAATPPS---QPPQQPSSMQTGMNPSA-MQGPSPPP 179
            P   P     +P   PF        AATPPS    P   P        P+A +  P   P
Sbjct: 1012 PAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGP 1071

Query: 180  PPPSYMHIPRYSTNPITVTVSQNLPSGQTVPRALQILPQIPSNLYGSP-GSIYIRQTSQS 238
              PS    P   T P     S   P G     + +  P  P+    SP G +    T   
Sbjct: 1072 ATPSLKGAP---TPPAATPPS---PKGGPATPSPKGAPMPPAATPPSPKGGL---ATPPH 1122

Query: 239  SSGRQTPQSTPWQSSPQGPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQIPQSAYHSPPPS 298
                 TP +TP   SP+G +     +  P  P      PS         P+    +PPP 
Sbjct: 1123 KGAPTTPAATP--PSPKGGLATPPPKGAPTTPAAT--PPS---------PKGGLATPPPK 1169

Query: 299  QCP-SPFSSPQHQ----VQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHSVAYLPY 353
              P +P ++P         PS  G    P +P+ TPP P + G  +   +G+ +    P 
Sbjct: 1170 GAPTTPAATPPSPKGGLATPSPKG---APTTPAATPPSP-KGGLATPSPKGAPTT---PA 1222

Query: 354  TASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQPSPWNQHSLYTATTPPSSSPS-- 411
                  KG +     T  P   P T     PSP     +P  +     A TPP+++P   
Sbjct: 1223 ATPPSPKGGL----ATPSPKGAPTTPAATPPSPKGGPATPPPK----GAPTPPAATPPSL 1274

Query: 412  RGISSQPKPPFSVNPVYITYTQPTG------PSCTPSPSPRVIPNP 451
            +G  + P    + NP  +T   P G      P   P+P     P+P
Sbjct: 1275 KGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSP 1320



 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 72/299 (24%), Positives = 115/299 (38%), Gaps = 28/299 (9%)

Query: 169  PSAMQGPSPPPP--PPSYMHIPRYSTNPITVTVSQN---LPSGQTVPRALQILPQIPSNL 223
            P ++  PS PP   PP    +   S       V+ +    P+  +   A        + L
Sbjct: 731  PKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYL 790

Query: 224  YGSPGSIYIRQTSQSSSGRQTPQSTPWQSSPQGPVPHYSQRPLPVYPHQQNYQP-SQYSP 282
              SP  + +  + Q+    + P +    + P  P+ + S    PV P + ++ P +  S 
Sbjct: 791  ADSPSPLGVSVSPQT----KRPPTKKGSAGPDTPIGNLSS---PVSPVEASFLPENSLSF 843

Query: 283  KQQQIPQSAYHSPPPSQCPSPFSSPQHQ-VQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQ 341
            +  +   +  HSP P   PSP  +P    V P     + +PP  + TP       P    
Sbjct: 844  QGSKDSPATTHSPTP---PSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFP---- 896

Query: 342  KQGSHSVAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPS--PISNQPSPWNQHSL 399
            K+G  + A     A S++  S KK   T  P   P +   +     P +  PSP    + 
Sbjct: 897  KEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPAT 956

Query: 400  YT---ATTPPSSSP--SRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
             +   A TPP+++P   +G  + P P  +  P   T   P G   TPSP     P   T
Sbjct: 957  PSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVT 1015



 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 81/336 (24%), Positives = 111/336 (33%), Gaps = 65/336 (19%)

Query: 124  PHSAPAVVAATPNYNPFFMNEQNRSAA--TPPSQPPQQPSSMQTGMNPSAMQGP-SPPPP 180
            P  AP   AATP      +       A  TP + PP     + T     A   P + PP 
Sbjct: 1145 PKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPS 1204

Query: 181  PPSYMHIPRYSTNPITVTVSQNLPSGQTVPRALQILPQIPSNLYGSPGSIYIRQTSQSSS 240
            P   +  P     P T   +   P G     + +  P  P+    SP         +   
Sbjct: 1205 PKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSP---------KGGP 1255

Query: 241  GRQTPQSTPWQSSPQGPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQIPQSAYHSPPPSQC 300
                P+  P   +P    P   +  L   PH+    P+  +P     P+    + PP   
Sbjct: 1256 ATPPPKGAP---TPPAATPPSLKGGLATPPHKGAPNPAVVTPPS---PKGGPATSPPKGA 1309

Query: 301  PSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQG---PPSYQKQGSHSVAYLPYTASS 357
            P+P ++               PPSP  +P  P  +G   PP+           LP T  S
Sbjct: 1310 PTPPAA--------------TPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPS 1355

Query: 358  LSKGSMKKIEITVEPSQRPGTAINRSPSPISNQPSPWNQHSLYTATTPPSSSPSRGISSQ 417
             SKG          PS + G      P+P +  PS    H    A TPP  SP RG  + 
Sbjct: 1356 -SKGG------PTTPSSKEG------PTPPAATPS----HKGGPAMTPP--SPKRG-PAI 1395

Query: 418  PKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            P P             PT P+  P    +    P T
Sbjct: 1396 PSPK----------GDPTSPAVIPLSPKKAPATPVT 1421



 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 84/339 (24%), Positives = 123/339 (36%), Gaps = 48/339 (14%)

Query: 126  SAPAVVAATPNYNPFFMNEQNRSAATPPSQPP-----QQPSSMQTGMNPSAMQGPSPPPP 180
            SA A VA++P   P    E + ++AT  S+         PS +   ++P   + P+    
Sbjct: 758  SALAPVASSPKECP---TEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTK--- 811

Query: 181  PPSYMHIPRYSTNPITVTVSQNLPSGQTVPRALQILPQIPSNLYGSPGSIYIRQ--TSQS 238
                    + S  P T   + + P     P     LP+   +  GS  S       T  S
Sbjct: 812  --------KGSAGPDTPIGNLSSPVS---PVEASFLPENSLSFQGSKDSPATTHSPTPPS 860

Query: 239  SSGRQTPQS-TPWQSSPQGPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQIPQSAYHSPPP 297
              G  TP + TP   SP+G      + P P   +    +    +P  +Q P  +  S  P
Sbjct: 861  PKGAPTPSAVTPL--SPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSP 918

Query: 298  SQC---PSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHSVAYLPYT 354
             +    P+P   P     PS  G    P  P+ TPP P  +G P+     + S  + P T
Sbjct: 919  KKARATPAPKGIP---ASPSPKG---APTPPAATPPSP--KGGPA-----TPSPKWAP-T 964

Query: 355  ASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQPSPWNQHSLYTATTPPSSSPSRGI 414
              + +  S K    T  P   P       PSP     +P    S   A TPP+ +P    
Sbjct: 965  PPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATP----SPKGAPTPPAVTPPSPK 1020

Query: 415  SSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
             S    PF           P  P  +P+ +P     PTT
Sbjct: 1021 GSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTT 1059



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 98/413 (23%), Positives = 151/413 (36%), Gaps = 62/413 (15%)

Query: 128  PAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTG----MNPSAMQG-PSPPP--- 179
            PA+   +P   P         A   P + P  PSS +      + PS  +G PSP     
Sbjct: 1551 PAMTVPSPKKTP---------AIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLI 1601

Query: 180  PPPSYMHIPRYSTNPITVTV-SQNLPSGQTVPRALQILPQI-PSNLYGSPGSIYIRQTSQ 237
            PP      P+ +  P  VT  S         P+     P + PS+L  SP S     +  
Sbjct: 1602 PPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTS---PASVT 1658

Query: 238  SSSGRQTPQSTPWQSSPQGPVPHYSQRPLPVYPHQQNYQPSQYSP--KQQQIPQSAYHSP 295
               G   PQ++    + +GP    + + + V P  ++  P   +P  K  Q  +S+  SP
Sbjct: 1659 CKMGATVPQASKGLPAKKGPT---ALKEVLVAPAPES-TPIITAPTRKGPQTKKSSATSP 1714

Query: 296  PPSQCPSPFSS-----PQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHSVAY 350
            P   CP P +      P   V P+ L  + +    S T         P        S A 
Sbjct: 1715 PI--CPDPSAKNGSKGPLSTVAPAPL--LPVQKDSSKTAKGKDASHSPKGPLAPPESKAS 1770

Query: 351  LPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQPSPWNQHSLYTATTPPSSSP 410
             P TA++  K   K    +V  +  P  ++  +PSP+   P    Q  L ++      SP
Sbjct: 1771 TPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPP--KQQFLPSSPGLVLESP 1828

Query: 411  SRGISSQPKPPF--SVNPVYITYTQPTGPSCTPSPSPRV--IPNPT-----TVFKITVGR 461
            S+ ++   +      + P  I+   P        P+P+   IP PT      V K   G 
Sbjct: 1829 SKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGS 1888

Query: 462  AT----TENLLNLVDQEERSAAPEPIQ----------PISVIPGSGGEKGSHK 500
             T     E++  L +Q+   A  +  Q          P+S    S  EK + K
Sbjct: 1889 GTESDSDESVPELEEQDSTQATTQQAQLAAAAEIDEEPVSKAKQSRSEKKARK 1941



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 72/302 (23%), Positives = 112/302 (37%), Gaps = 67/302 (22%)

Query: 191 STNPITVTVSQNLPSGQT-----VPRALQIL-PQIPSNL-------YGSPGSIY----IR 233
           +T P+  T S+N P   +      P A  +L P+IP ++        G+P        I 
Sbjct: 696 TTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGIS 755

Query: 234 QTSQSSSGRQTPQSTPWQ-------SSPQGPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQ 286
            TS  +    +P+  P +       +S +G + + +  P P+            SP+ ++
Sbjct: 756 HTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPL--------GVSVSPQTKR 807

Query: 287 IPQ---SAYHSPPPSQCPSPFSSPQHQVQP-SQLGHIFMPPSPSTT--PPHPYQQGPPSY 340
            P    SA    P     SP S  +    P + L       SP+TT  P  P  +G P+ 
Sbjct: 808 PPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPT- 866

Query: 341 QKQGSHSVAYLPYTASSLS-KGSMKKIEITVEPSQRPGTAINRSPSPISNQPSPWNQHSL 399
                      P   + LS KG      +T+ P + P  ++   P P     +P  + + 
Sbjct: 867 -----------PSAVTPLSPKG------VTLPPKETPTPSVVNLPFPKEGPATPAPKQA- 908

Query: 400 YTATTPPSSSPSR--------GISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNP 451
             A +  SSSP +        GI + P P  +  P   T   P G   TPSP     P  
Sbjct: 909 -PALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPA 967

Query: 452 TT 453
            T
Sbjct: 968 AT 969



 Score = 37.7 bits (86), Expect = 0.037
 Identities = 88/364 (24%), Positives = 128/364 (35%), Gaps = 50/364 (13%)

Query: 109 PQHAAGKQLICLVQEPHSAPAVVAATPNY---NPFFMNEQNRSAATPPSQPPQQPSSMQT 165
           P  +A   L+ L   PHS     A  PN     P     ++ S  T  +  P  PS  +T
Sbjct: 131 PSSSAPLALVALA--PHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSA--PIAPSEPKT 186

Query: 166 GMN--PSAMQGPSP---PPPPPSYMHIPRYSTNPITVTVSQNLPSGQTVPRALQIL--PQ 218
            +N  PS +  P+P   P PP     +P +   P+    S      QT P     +  PQ
Sbjct: 187 NLNKVPSEVV-PNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQ 245

Query: 219 IPSNLYGSPGSIYIRQTSQSSSGRQTPQSTPWQSSPQGPVPHYSQRPLPVYPHQQNYQPS 278
           +      S         S S  G  +P +    S+   PV   SQ+     P+     P 
Sbjct: 246 VKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAG--PNTPPDFPI 303

Query: 279 QYSPKQQQIPQSAYHSPP--PSQCPSPFSSPQHQ---VQPSQLGHIFMPPSPSTTPPHPY 333
                   + QS++ S        PS  S P  +   V  S  G  + P   S  PP P 
Sbjct: 304 SLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASY-PSQRSVIPPLP- 361

Query: 334 QQGPPSYQKQGSHSVAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQPSP 393
                S  +    +VA  P  A S+ KG      IT  PS     A + S SP +     
Sbjct: 362 -----SRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTT----- 411

Query: 394 WNQHSLYTATTPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
               SL   ++P ++     ++  P       P+ +T        CT      +   PTT
Sbjct: 412 ----SLILKSSPNATYHYPLVAQMPVSSVGTTPLVVT------NPCT------IAAAPTT 455

Query: 454 VFKI 457
            F++
Sbjct: 456 TFEV 459


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 68.6 bits (166), Expect = 2e-11
 Identities = 103/385 (26%), Positives = 136/385 (35%), Gaps = 46/385 (11%)

Query: 124 PHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGP--SPPPPP 181
           P  AP  + A P+       E   S ATPP Q P   +S      PS    P  +PPP  
Sbjct: 562 PCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQA 621

Query: 182 PSYMHIPRYSTNPITVTVSQNLPSGQTVPRALQILPQIPSNLYGSPGSIYIRQTSQSSSG 241
           P  + +P     P       + P+   +       PQ P+ L     ++++ Q   S   
Sbjct: 622 PPXLALPPLQAPP-------SPPASPPLSPLATPSPQAPNAL-----AVHLLQAPFSP-- 667

Query: 242 RQTPQSTPWQ---SSPQGPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQIPQSAYHSPPPS 298
              P S P Q   S P  P    S  P    P      P Q  P     P  +  + PP 
Sbjct: 668 ---PPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP 724

Query: 299 QCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPP--------HPYQQGPPSYQKQGSHSVAY 350
           Q P P ++P  QV PS       P SPS TPP         P  Q PPS       S   
Sbjct: 725 QAPPPLAAPPLQVPPSPPAS--PPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLA 782

Query: 351 LPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPS---PISNQPSPWNQHSLYTAT---- 403
            P   +  +  +     +   P+  PG A   SPS   P+S   +P  Q     A     
Sbjct: 783 KPPPQAPPALATPPLQALPSPPASFPGQA-PFSPSASLPMSPLATPPPQAPPVLAAPLLQ 841

Query: 404 TPPSSSPSRGISSQPKPP-----FSVNPVYITYTQPTGPSCTPSPSP-RVIPNPTTVFKI 457
            PPS   S  + +  +PP      SV+   +T     GP   PS SP   +  P      
Sbjct: 842 VPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHS 901

Query: 458 TVGRATTENLLNLVDQEERSAAPEP 482
           +   +T E L       E  AA  P
Sbjct: 902 SSATSTPEELRGYDSGPEGGAAASP 926



 Score = 60.1 bits (144), Expect = 7e-09
 Identities = 118/482 (24%), Positives = 170/482 (35%), Gaps = 93/482 (19%)

Query: 60  SPDDNRMNRNRLLHINLGIHSPS-SYHPGDGAQLNGGRTLVHSSSD-GHIDPQHAAGKQL 117
           +P      R+R     +G+  P+ S  P    +  G R  V S+S+    +P  AA ++ 
Sbjct: 171 TPSPAMARRSRAAGTEVGLPRPAPSARPRPPTE--GPRKSVSSASEHSTTEPSPAARRRP 228

Query: 118 ICL--VQEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQ-QPSSMQTGMNP----- 169
                +Q P S     +ATP  +P       R     P+ P Q +P  +Q    P     
Sbjct: 229 SAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPP 288

Query: 170 -------------SAMQGPSP------PPPPPSYMHIPRYSTNPITVTVSQNLPSGQTVP 210
                        S +  PSP      P PPP     P  +T P +  ++  LP     P
Sbjct: 289 RKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSP 348

Query: 211 RALQILPQIPSNLYGSPGSIYIRQTSQSSSGRQTPQSTPWQSSPQGPVPHYSQRPLPVYP 270
            A   L  +PS                       P +TP   +P    P  +  P+   P
Sbjct: 349 SAPPSLQTLPS-----------------------PPATPPSQAP----PSMTTPPMQAPP 381

Query: 271 HQQNYQPSQYSPKQQQIPQSAYHSPPPSQCPSPFSSPQHQVQPS------QLGHIFMPPS 324
             Q   P        Q+P S   SP     PSP +    Q   S      Q  H F+  S
Sbjct: 382 SLQTIPPI-------QVPHS-LTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMS 433

Query: 325 PS------TTPPHPYQQGPPSYQKQGSHSVAYLPYTASSLSKG-SMKKIEITVEPSQRPG 377
           P       T+P  P    P S   Q   S+   P   +SLS   S     +T+ P Q   
Sbjct: 434 PRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALS 493

Query: 378 TAINRSP-SPISN--QPSPWNQHSLY--TATTPPSS---SPSRGISSQPKPPFSVNPVYI 429
           +  + SP +P+S+   P    Q SL   +  TPP+S    P   + S   PP       +
Sbjct: 494 SLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPL 553

Query: 430 TYTQPTGPSCTPSPSP-RVIPNPTTVFKITVGRATTENLLNLVDQEERSAAPEPIQPISV 488
           T      P C P+P P +  P+P T    T    T  ++     Q   + A  P+Q +  
Sbjct: 554 TTPHLETPPC-PAPCPLQAPPSPLT----TPPPETPSSIATPPPQAPPALASPPLQGLPS 608

Query: 489 IP 490
            P
Sbjct: 609 PP 610



 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 85/356 (23%), Positives = 129/356 (36%), Gaps = 71/356 (19%)

Query: 145 QNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPPPPPSYMHIPRYSTNPITV-TVSQNL 203
           ++ S  TP +  P      +       +  P+P   P      PR S +  +  + ++  
Sbjct: 162 RDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPS 221

Query: 204 PSGQTVPRALQILPQIPSNLYGSPGSIYIRQTSQSSSGRQTPQSTPWQSSPQGPVPHYSQ 263
           P+ +  P A               G    R  S+S S   TP S+P +S P       S 
Sbjct: 222 PAARRRPSA---------------GGGLQRPASRSLSSSATPLSSPARSGP-------SA 259

Query: 264 RPLPVYPHQQNYQPSQYSPKQQQIPQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPP 323
           R  P  P      PSQ  PK  Q  +    +PP     +P   P   +  S L      P
Sbjct: 260 RGTPRAPAH----PSQPKPKGLQALRPPQVTPPRKDA-APALGP---LSSSPLA----TP 307

Query: 324 SPSTTPPHPYQQGPPSYQKQGSHSVAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRS 383
           SPS T   P    PP             P  A++        +  T+ PS    T +  +
Sbjct: 308 SPSGTKARPV---PP-------------PDNAAT-------PLPATLPPSPPLATPLPLA 344

Query: 384 PSPISNQPSPWNQHSLYTATTPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSP 443
           P      PSP    SL T  +PP++ PS+   S   PP    P   T      P    SP
Sbjct: 345 P------PSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSP 398

Query: 444 SPRVIPNPTTVFKI----TVGRAT---TENLLNLVDQEERSAAPEPIQPISVIPGS 492
           S +  P+P  +  +    ++G  T   T + L +  ++ +++   P +P S  P S
Sbjct: 399 SLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDS 454



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 98/403 (24%), Positives = 142/403 (35%), Gaps = 96/403 (23%)

Query: 121  VQEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPPP 180
            +Q P S PA    +P+  P            P + PP     +Q   +P     P+ PP 
Sbjct: 704  LQVPPSPPASPPMSPSATP-----------PPQAPPPLAAPPLQVPPSP-----PASPPM 747

Query: 181  PPSYMHIPRYSTNPITVTVSQNLPSGQTVPRALQILPQIPSNLYGSPGSIYIRQTSQSSS 240
             PS    PR             +P     P  LQ+ P  P++L   P S   +   Q+  
Sbjct: 748  SPSATPPPR-------------VPPLLAAP-PLQVPPSPPASL---PMSPLAKPPPQAPP 790

Query: 241  GRQTPQSTPWQSSPQGPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQIPQSAYHSPPPSQC 300
               TP   P Q+ P  P           +P Q  + PS        +P S   +PPP Q 
Sbjct: 791  ALATP---PLQALPSPPAS---------FPGQAPFSPS------ASLPMSPLATPPP-QA 831

Query: 301  PSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHSVAYLPYTASSLSK 360
            P   ++P  QV          PPSP  +P     + PP+            P   +S+S 
Sbjct: 832  PPVLAAPLLQV----------PPSPPASPTLQAPRRPPT------------PGPDTSVS- 868

Query: 361  GSMKKIEITVEPSQRPGTAINRSPSPISNQPSPWNQHSLYTATTPP-----SSSPSRGIS 415
            G    + +   P   P    +RSPS   + P     HS    +TP       S P  G +
Sbjct: 869  GPRLTLALAPGPPPPP----SRSPSSTLSGPD-LAGHSSSATSTPEELRGYDSGPEGGAA 923

Query: 416  SQPKPPFSVNPVYITYTQPTGPSCTPSP--SPRVIPNPTTVFKITVGRATTENLLNLVDQ 473
            + P P        +    P   S  P+P  + R  P     +    G  + + L  + + 
Sbjct: 924  ASPPP-----DAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYET 978

Query: 474  E-ERSAAPEP--IQPISVIPGSGGEKGSHKYQRSSSSGSDDYA 513
            E   SA P P  + P    PG+ G K +      +SS S   A
Sbjct: 979  EGPESATPAPGALDP-GPSPGTSGGKAAAGAGAGASSRSPKQA 1020


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 68.2 bits (165), Expect = 3e-11
 Identities = 102/405 (25%), Positives = 153/405 (37%), Gaps = 49/405 (12%)

Query: 60  SPDDNRMNRNRLLHINLGIHSPS-SYHPGDGAQLNGGRTLVHSSSD-GHIDPQHAAGKQL 117
           +P      R+R     +G+  P+ S  P    +  G R  V S+S+    +P  AA ++ 
Sbjct: 162 TPSPAMARRSRAAGTEVGLPRPAPSARPRPPTE--GPRKSVSSASEHSTTEPSPAARRRP 219

Query: 118 ICL--VQEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQ-QPSSMQTGMNPSAMQG 174
                +Q P S     +ATP  +P       R     P+ P Q +P  +Q    P     
Sbjct: 220 SAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQV--- 276

Query: 175 PSPPPPPPSYMHIPRYSTNPITVTVSQNLPSGQTVPRALQILPQIPSNLYGSPGSIYIRQ 234
              PP   +   +   S++P+  T S + P   + P +LQ LP  P+    +P S     
Sbjct: 277 --TPPRKDAAPALGPLSSSPL-ATPSPSAPPSPSAPPSLQTLPSPPA----TPPS----- 324

Query: 235 TSQSSSGRQTPQSTPWQSSPQGPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQIPQSAYHS 294
            + +S G  T Q+T        P P  S    P         P Q  P     P  A  S
Sbjct: 325 QATTSLGSPTLQAT----HSFLPSPPLSPLATP---------PPQAPPALALPPLQAPPS 371

Query: 295 PPPSQCPSPFSSPQHQVQPSQLGHIFMPP-SPSTTPPHPYQQGPPSYQKQGSHSVAYLPY 353
           PP S   SP ++P  Q   +   H+   P SP  +PP      PP+       +      
Sbjct: 372 PPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSA------ 425

Query: 354 TASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQPSPWNQHSLYTATTPPSSSPSRG 413
           T  S +  S+    + V PS      ++ S +P    P P     L  A  PP + P+  
Sbjct: 426 TPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALA 485

Query: 414 ---ISSQPKPPFSV---NPVYITYTQPTGPSCTPSP-SPRVIPNP 451
              + + P PP S     P   + + P  P  TP P +P V+  P
Sbjct: 486 TPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAP 530



 Score = 68.2 bits (165), Expect = 3e-11
 Identities = 103/375 (27%), Positives = 132/375 (35%), Gaps = 40/375 (10%)

Query: 121 VQEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPPP 180
           ++ P   P    A P   P      +   ATP    P  PS+      PS    PSPP  
Sbjct: 271 LRPPQVTPPRKDAAPALGPL----SSSPLATPSPSAPPSPSAP-----PSLQTLPSPPAT 321

Query: 181 PPSYMHIPRYSTNPITVTVSQNLPSGQTVPRALQILPQIPSNLYGSPGSIYIRQTSQSSS 240
           PPS       S  P        LPS    P A    PQ P  L   P        S  +S
Sbjct: 322 PPSQATTSLGS--PTLQATHSFLPSPPLSPLATPP-PQAPPALALPPLQA---PPSPPAS 375

Query: 241 GRQTPQSTPWQSSPQGPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQIPQSAYHSPPPSQC 300
              +P +TP   +P     H  Q P    P      P  +SP     P  +  + PPSQ 
Sbjct: 376 PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAP--FSPPAS--PPVSPSATPPSQA 431

Query: 301 PSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHSVAYLPYTASSLSK 360
           P   ++P  QV PS       P SPS TPP    Q PP             P    +L+ 
Sbjct: 432 PPSLAAPPLQVPPSPPAS--PPMSPSATPP---PQAPPPLAAPPLQLAKPPPQAPPALAT 486

Query: 361 GSMKKIEITVEPSQRPGTAINRSPS---PISNQPSPWNQHSLYTAT----TPPSSSPSRG 413
             ++   +   P+  PG A   SPS   P+S   +P  Q     A      PPS   S  
Sbjct: 487 PPLQ--ALPSPPASFPGQA-PFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPT 543

Query: 414 ISSQPKPP-----FSVNPVYITYTQPTGPSCTPSPSP-RVIPNPTTVFKITVGRATTENL 467
           + +  +PP      SV+   +T     GP   PS SP   +  P      +   +T E L
Sbjct: 544 LQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEEL 603

Query: 468 LNLVDQEERSAAPEP 482
                  E  AA  P
Sbjct: 604 RGYDSGPEGGAAASP 618



 Score = 64.7 bits (156), Expect = 3e-10
 Identities = 78/332 (23%), Positives = 118/332 (35%), Gaps = 57/332 (17%)

Query: 145 QNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPPPPPSYMHIPRYSTNPITV-TVSQNL 203
           ++ S  TP +  P      +       +  P+P   P      PR S +  +  + ++  
Sbjct: 153 RDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPS 212

Query: 204 PSGQTVPRALQILPQIPSNLYGSPGSIYIRQTSQSSSGRQTPQSTPWQSSPQG----PVP 259
           P+ +  P A               G    R  S+S S   TP S+P +S P        P
Sbjct: 213 PAARRRPSA---------------GGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAP 257

Query: 260 HYSQRPLPVYPHQQNYQPSQYSPKQQQ-------IPQSAYHSPPPSQCPSPFSSPQHQVQ 312
            +  +P P     Q  +P Q +P ++        +  S   +P PS  PSP + P  Q  
Sbjct: 258 AHPSQPKP--KGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTL 315

Query: 313 PS------------------QLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHSVAYLPYT 354
           PS                  Q  H F+P  P +    P  Q PP        ++A  P  
Sbjct: 316 PSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPP--------ALALPPLQ 367

Query: 355 ASSLSKGSMKKIEITVEPSQRPGT-AINRSPSPISNQPSPWNQHSLYTATTPPSSSPSRG 413
           A      S     +     Q P   A++   +P S  PSP  Q       +PP  SPS  
Sbjct: 368 APPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPP-VSPSAT 426

Query: 414 ISSQPKPPFSVNPVYITYTQPTGPSCTPSPSP 445
             SQ  P  +  P+ +  + P  P  +PS +P
Sbjct: 427 PPSQAPPSLAAPPLQVPPSPPASPPMSPSATP 458


>gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sapiens]
          Length = 2161

 Score = 68.2 bits (165), Expect = 3e-11
 Identities = 98/407 (24%), Positives = 146/407 (35%), Gaps = 64/407 (15%)

Query: 78   IHSPSSYHPGDGAQLNGGRTLVHSSSDGHIDPQHAAGKQLICLVQEPHSAPAVVAATPNY 137
            I +  S  PG  A L   R     +++   DP H A        Q  +  P+ +   P  
Sbjct: 833  ISASESPGPGGLASLGKHRPKGFFATESSFDPHHRA--------QPSYERPSFLPPGPG- 883

Query: 138  NPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPPPPPSYMHIPRYSTNPITV 197
                M  Q    A    +P   P +M+   + S       PPPP +    P YST P+  
Sbjct: 884  ---LMLRQKSIGAAEDDRPYLAPPAMKFSRSLSVPGSEDIPPPPTTSPPEPPYSTPPVPS 940

Query: 198  TVSQNLPSGQTVPRALQILPQIPSNLYGSPGSIYIRQTSQSSSGRQTPQSTPWQSSPQGP 257
            +  +  PS +  P        +P++   S        T   S  +    S P   +   P
Sbjct: 941  SSGRLTPSPRGGPFNPGSGGPLPASSPASFDGPSPPDTRVGSREKSLYHSGPLPPAHHHP 1000

Query: 258  VPHYSQRPLPVYPHQQNYQPSQYSPKQQQIPQSAYHSPPPSQCPSPFSSPQHQVQPSQLG 317
              H+     P  PH  +  P    P + +   S    PPP     P        QPS  G
Sbjct: 1001 PHHHHHHAPPPQPHHHHAHPPH--PPEMETGGSP-DDPPPRLALGP--------QPSLRG 1049

Query: 318  HIFMPPSPSTTPPHP-----------YQQGPP----SYQKQGSHSVAYLPYTASSLSKGS 362
                 PSP+   P P             QGP         + + +  Y+P  +    KG 
Sbjct: 1050 WRGGGPSPTPGAPSPSHHGSAGGGGGSSQGPALRYFQLPPRAASAAMYVPARSGRGRKGP 1109

Query: 363  M-KKIEITVEPSQRPGTAINRSP-SPISNQP-----SPWNQHSLYTAT-------TPPSS 408
            + K+ ++  EP +  G     SP SP S QP     +P  ++S+   T       T  S 
Sbjct: 1110 LVKQTKVEGEPQKGGGLPPAPSPTSPASPQPPPAVAAPSEKNSIPIPTIIIKAPSTSSSG 1169

Query: 409  SPSRGISSQPKPPFSVNPVYITYTQPT----GPSCTPSPSPRVIPNP 451
              S+G S++ +PP        T  +PT    G   +PSP+P + P P
Sbjct: 1170 RSSQGSSTEAEPP--------TQPEPTGGGGGGGSSPSPAPAMSPVP 1208



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 21/71 (29%), Positives = 31/71 (43%), Gaps = 1/71 (1%)

Query: 128  PAVVAATPNYNPFFMNEQNRSA-ATPPSQPPQQPSSMQTGMNPSAMQGPSPPPPPPSYMH 186
            P ++   P+ +    + Q  S  A PP+QP         G +PS     SP PP PS + 
Sbjct: 1156 PTIIIKAPSTSSSGRSSQGSSTEAEPPTQPEPTGGGGGGGSSPSPAPAMSPVPPSPSPVP 1215

Query: 187  IPRYSTNPITV 197
             P   + P T+
Sbjct: 1216 TPASPSGPATL 1226



 Score = 33.5 bits (75), Expect = 0.70
 Identities = 70/297 (23%), Positives = 98/297 (32%), Gaps = 70/297 (23%)

Query: 84   YHPGDGAQLNGGRTLVHSSSDGHIDPQHAAGKQLICLVQEPHSAPAVVAATPNYNPFFMN 143
            ++PG G  L        +S DG   P    G +   L    HS P   A   +++P   +
Sbjct: 954  FNPGSGGPLPASSP---ASFDGPSPPDTRVGSREKSLY---HSGPLPPA---HHHPPHHH 1004

Query: 144  EQNRSAATPPSQP------PQQPSSMQTGMNPSAMQ-----------------GPSPPPP 180
              +     PP QP      P  P  M+TG +P                     GPSP P 
Sbjct: 1005 HHH----APPPQPHHHHAHPPHPPEMETGGSPDDPPPRLALGPQPSLRGWRGGGPSPTPG 1060

Query: 181  PPSYMHIPRYSTNPITVTVSQNLPSGQTVPRALQILPQIPSNLYGSPGSIYIRQTS---Q 237
             PS  H         + +    L   Q  PRA      +P+          ++QT    +
Sbjct: 1061 APSPSHHGSAGGGGGS-SQGPALRYFQLPPRAASAAMYVPARSGRGRKGPLVKQTKVEGE 1119

Query: 238  SSSGRQTPQSTPWQSSPQGPVPHYSQRPLPVYPHQQNYQP--------SQYSPKQQQIPQ 289
               G   P + P  +SP  P P     P    P ++N  P           S   +    
Sbjct: 1120 PQKGGGLPPA-PSPTSPASPQPP----PAVAAPSEKNSIPIPTIIIKAPSTSSSGRSSQG 1174

Query: 290  SAYHSPPPSQCPSPFS---------SPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGP 337
            S+  + PP+Q P P           SP   + P       +PPSPS  P      GP
Sbjct: 1175 SSTEAEPPTQ-PEPTGGGGGGGSSPSPAPAMSP-------VPPSPSPVPTPASPSGP 1223



 Score = 31.6 bits (70), Expect = 2.7
 Identities = 48/237 (20%), Positives = 82/237 (34%), Gaps = 29/237 (12%)

Query: 233  RQTSQSSSGRQTPQSTPWQSSPQ----GPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQIP 288
            R   +SS G   PQ  P   SP+     P PH+        P  + +  S   P ++++ 
Sbjct: 1362 RALKESSEGGGAPQPPPRPPSPRYEAPPPTPHHHSPHAHHEPVLRLWGASPPDPARRELG 1421

Query: 289  QSA----YHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQG 344
              A         P+  P+   S  H++ P+  G   +     T PP P+    P   K  
Sbjct: 1422 YRAGLGSQEKSLPASPPAARRSLLHRLPPTAPGVGPLLLQLGTEPPAPH----PGVSK-- 1475

Query: 345  SHSVAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQ----PSPWNQHSLY 400
                   P+ +++  +     + +    + +P   +     P S      P P  + S+ 
Sbjct: 1476 -------PWRSAAPEEPERLPLHVRFLENCQPRAPVTSGRGPPSEDGPGVPPPSPRRSVP 1528

Query: 401  TATTPPSSSPSRG----ISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
             + T P +S   G    +   P P   V      + +P  P    S S     +P T
Sbjct: 1529 PSPTSPRASEENGLPLLVLPPPAPSVDVEDGEFLFVEPLPPPLEFSNSFEKPESPLT 1585



 Score = 31.2 bits (69), Expect = 3.5
 Identities = 39/182 (21%), Positives = 65/182 (35%), Gaps = 28/182 (15%)

Query: 158  QQPSSMQTGMNPSAMQGPSPPPPPPSYMHIPRYSTNPITVTVSQNLPSGQTVPRALQILP 217
            Q  + + +G  P +  GP  PPP P    +P   T+P   +    LP     P A  +  
Sbjct: 1499 QPRAPVTSGRGPPSEDGPGVPPPSPR-RSVPPSPTSP-RASEENGLPLLVLPPPAPSVDV 1556

Query: 218  QIPSNLYGSPGSIYIRQTSQSSSGRQTPQSTPWQSSPQGPVPHYSQRPLPVYPHQQNYQP 277
            +    L+  P    +    + S+  + P+S P    P  P+P       P+ P       
Sbjct: 1557 EDGEFLFVEP----LPPPLEFSNSFEKPES-PLTPGPPHPLPDTPAPATPLPP------- 1604

Query: 278  SQYSPKQQQIPQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGP 337
                     +P  A  + PP+   +  S   +  + + L         S  P  P+  GP
Sbjct: 1605 ---------VPPPAVAAAPPTLDSTASSLTSYDSEVATL-----TQGASAAPGDPHPPGP 1650

Query: 338  PS 339
            P+
Sbjct: 1651 PA 1652



 Score = 30.0 bits (66), Expect = 7.8
 Identities = 70/301 (23%), Positives = 104/301 (34%), Gaps = 54/301 (17%)

Query: 153  PSQPPQQPSSMQTGMNPSAMQGPSPPPPP-PSYMHIPRYST-----NPITVTVSQNLPSG 206
            P  P    SS+   + P   +GP PPPPP P  +  P+ S        I   +S  L   
Sbjct: 1823 PPVPLPTASSLPRKLLPWE-EGPGPPPPPLPGPLAQPQASALATVKASIISELSSKLQQF 1881

Query: 207  QTVPRALQILPQIPSNLYGS-----PGSIYIRQTSQS-----------SSGRQTPQSTPW 250
                 A   LP       G       G+ Y+ + + S           SS    P S+ +
Sbjct: 1882 GGSSAAGGALPWARGGSGGGGDSHHGGASYVPERTSSLQRQRLSDDSQSSLLSKPVSSLF 1941

Query: 251  QSSPQGPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQIPQSAYHSPPPSQCPS-PFSSPQH 309
            Q+ P+ P+P     PLP          +  SP     P +   S   S   +      + 
Sbjct: 1942 QNWPKPPLP-----PLPT--------GTGVSPTAAAAPGATSPSASSSSTSTRHLQGVEF 1988

Query: 310  QVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHSVAYLPYTASSLSKGSMKKIEIT 369
            +++P  L      PSPS  P   ++  P           A  P +   L  G +      
Sbjct: 1989 EMRPPLLRR---APSPSLLPASEHKVSP-----------APRPSSLPILPSGPLYPGLFD 2034

Query: 370  VEPSQRPGTAINRSP-SPISNQPSPWNQHSLYTATTPPSS--SPSRGISSQPKPPFSVNP 426
            +  S   G   +  P +P+   P P     L  A +  S   SP+R +S  P  PF   P
Sbjct: 2035 IRGSPTGGAGGSADPFAPVFVPPHPGISGGLGGALSGASRSLSPTRLLSLPPDKPFGAKP 2094

Query: 427  V 427
            +
Sbjct: 2095 L 2095


>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
          Length = 748

 Score = 67.4 bits (163), Expect = 4e-11
 Identities = 84/347 (24%), Positives = 122/347 (35%), Gaps = 47/347 (13%)

Query: 233 RQTSQSSSGRQTPQSTPWQSSPQGPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQIPQSAY 292
           +Q  Q +   Q P   P    PQ P      + L    H Q++QP    P Q Q P  A 
Sbjct: 257 QQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQP----PPQPQQPPVAQ 312

Query: 293 HSP---PPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHSVA 349
           + P   PP     P  S Q Q  P Q+ +   PP      P   QQ P   Q Q   +  
Sbjct: 313 NQPSQLPPQSQTQPLVS-QAQALPGQMLYT-QPPLKFVRAPMVVQQPPVQPQVQQQQTAV 370

Query: 350 YLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQPSPWNQ-HSLYTATTPPSS 408
                A  ++                PG  +++S  P+ + PSP  Q  +  +   PP  
Sbjct: 371 QTAQAAQMVA----------------PGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQP 414

Query: 409 SPSRG-ISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTTVFKITVGRATTENL 467
           SP  G  SSQP    S  P       P+  S  PSPSP+   +P T         T +N 
Sbjct: 415 SPQPGQPSSQPNSNVSSGPA------PSPSSFLPSPSPQPSQSPVTA-------RTPQNF 461

Query: 468 LNLVDQEERSAAPEPIQPISVIPGSGGEKGSHKYQRSSSSGSDDYAYTQALLLHQRARME 527
                         P+ P SV+  +G  +   +           Y      ++++  + E
Sbjct: 462 ----SVPSPGPLNTPVNPSSVMSPAGSSQAEEQQYLDKLKQLSKYIEPLRRMINKIDKNE 517

Query: 528 RLAKQLKLEKEELERLKSEVNGMEHDLMQR---RLRRVSCTTAIPTP 571
              K L   K  L+ L           +Q+    L ++    A+PTP
Sbjct: 518 DRKKDLSKMKSLLDILTDPSKRCPLKTLQKCEIALEKLKNDMAVPTP 564



 Score = 49.7 bits (117), Expect = 9e-06
 Identities = 53/184 (28%), Positives = 62/184 (33%), Gaps = 9/184 (4%)

Query: 152 PPSQPPQQPSSMQTGMNPSAMQGPSPPPPPPSYMHIPRYSTNPITVTVSQNLPSGQTVPR 211
           PP Q PQ P S         M       PPP     P     P     SQ  P  QT P 
Sbjct: 273 PPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQP-----SQLPPQSQTQPL 327

Query: 212 ALQILPQIPSNLYGSPGSIYIRQTSQSSSGRQTPQSTPWQSSPQGPVPHYSQRPLPVYPH 271
             Q        LY  P   ++R           PQ    Q++ Q      +Q   P    
Sbjct: 328 VSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQ--TAQAAQMVAPGVQV 385

Query: 272 QQNYQPSQYSPKQQQIPQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPH 331
            Q+  P   SP   Q  Q+    PPP Q PSP    Q   QP+        PSPS+  P 
Sbjct: 386 SQSSLPMLSSPSPGQQVQTPQSMPPPPQ-PSP-QPGQPSSQPNSNVSSGPAPSPSSFLPS 443

Query: 332 PYQQ 335
           P  Q
Sbjct: 444 PSPQ 447



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 68/298 (22%), Positives = 96/298 (32%), Gaps = 60/298 (20%)

Query: 110 QHAAGKQLICLVQEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMN- 168
           Q    +Q     Q P   P +    P  +     +  +   T   QPP QP       N 
Sbjct: 255 QQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQ 314

Query: 169 -----------PSAMQGPSPP------PPPPSYMHIPR-YSTNPITVTVSQNLPSGQTVP 210
                      P   Q  + P       PP  ++  P      P+   V Q   + QT  
Sbjct: 315 PSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQ 374

Query: 211 RALQILPQIPSN-----LYGSPGSIYIRQTSQSSSGRQTPQSTPWQSSPQGPVPHYSQRP 265
            A  + P +  +     +  SP      QT QS      P   P Q S Q P  + S  P
Sbjct: 375 AAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQ-PNSNVSSGP 433

Query: 266 LPVYPHQQNYQPSQYSPKQQQIPQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSP 325
            P         PS + P           SP PSQ P    +PQ+   PS        P P
Sbjct: 434 AP--------SPSSFLPSP---------SPQPSQSPVTARTPQNFSVPS--------PGP 468

Query: 326 STTPPHPYQQGPPSYQKQGSHSVAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRS 383
             TP +P     P+   Q      YL           +K++   +EP +R    I+++
Sbjct: 469 LNTPVNPSSVMSPAGSSQAEEQ-QYL---------DKLKQLSKYIEPLRRMINKIDKN 516


>gi|54112403 chromodomain helicase DNA binding protein 7 [Homo
           sapiens]
          Length = 2997

 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 130/589 (22%), Positives = 214/589 (36%), Gaps = 83/589 (14%)

Query: 154 SQPPQQPSSMQTGMNPSAMQ---GPSPPPPPPSYMHIPRYSTNP-----ITVTVSQNLPS 205
           S  PQQ  SM   +  S  Q    PS      S  H PR+S NP     +          
Sbjct: 236 SHVPQQSPSMAPSLRHSVQQFHHHPSTALHGESVAHSPRFSPNPPQQGAVRPQTLNFSSR 295

Query: 206 GQTVPR-ALQILPQIPSNLYGSPGSIYIRQTSQSSSGRQTPQSTPWQSSPQGP----VPH 260
            QTVP   +    Q     Y +     +  T  + +   T  +   QS P+ P     P 
Sbjct: 296 SQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPNAVGFPS 355

Query: 261 YSQRPL----PVYPHQQNYQPSQYSPKQQQIPQSAYHSPPPSQ----CPSPFSSPQHQVQ 312
            S + L    P++P     Q +  +    Q PQ  Y SPPP        +P  +P  QV+
Sbjct: 356 NSGQGLMHQQPIHPSGSLNQMNTQTMHPSQ-PQGTYASPPPMSPMKAMSNPAGTPPPQVR 414

Query: 313 PSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHSVAYLPYTASSLSKG------SMKKI 366
           P   G   +P    + P  P+ Q  PS+Q  G+  +        ++ +       S    
Sbjct: 415 PGSAG---IPMEVGSYPNMPHPQ--PSHQPPGAMGIGQRNMGPRNMQQSRPFIGMSSAPR 469

Query: 367 EIT--VEPSQRPGTAINRSPSPISNQPSPWNQH-----SLYTATTPPSSSPSRGISSQPK 419
           E+T  + P+  PG  +   P  I  +  P  QH     S     T P   P  G+  Q  
Sbjct: 470 ELTGHMRPNGCPGVGLG-DPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSS 528

Query: 420 PPFSVNPVYITYTQ-PTGPSCTPSPSP------------RVIPNPTTVFKITVGRATTEN 466
           PP   +P +  + Q    P  TP   P            + +P+ T V         +++
Sbjct: 529 PP---HPHHQPWAQLHPSPQNTPQKVPVHQHSPSEPFLEKPVPDMTQVSGPNAQLVKSDD 585

Query: 467 LLNLVDQE--ERSAAPEPIQPISVIPGSG-------GEKGSHKYQRSSSSGSDDYAYTQA 517
            L  ++Q+  ++    +    ++  P  G       G   + +  R+S  GS +    + 
Sbjct: 586 YLPSIEQQPQQKKKKKKNNHIVAEDPSKGFGKDDFPGGVDNQELNRNSLDGSQEEKKKK- 644

Query: 518 LLLHQRARMERLAKQLKLEKEELERLKSEVNGMEHDLMQRRLRRVSCTTAIPTPEEMTRL 577
               +R++ ++  K+ K  KE+ E    E    +   + +  +     TA P P+   + 
Sbjct: 645 ----KRSKAKKDPKEPKEPKEKKE--PKEPKTPKAPKIPKEPKEKKAKTATPKPKSSKK- 697

Query: 578 RSMNRQLQINVDCTLKEVDLLQSRGNFDPKAMNNFYDNIEPGPVVPPKPSKKDSSDPCTI 637
            S N++         K+V+  ++ G+      N+  D   P P  PP+  +         
Sbjct: 698 -SSNKKPDSEASALKKKVNKGKTEGS-----ENSDLDKTPP-PSPPPEEDEDPGVQKRRS 750

Query: 638 ERKARRISVTSKVQADIHDTQAAAADE--HRTGSTQSPRTQPRDEDYEG 684
            R+ +R   T  ++  I D +A  AD     + S  S   Q    D EG
Sbjct: 751 SRQVKRKRYTEDLEFKISDEEADDADAAGRDSPSNTSQSEQQESVDAEG 799



 Score = 39.7 bits (91), Expect = 0.010
 Identities = 65/274 (23%), Positives = 104/274 (37%), Gaps = 49/274 (17%)

Query: 221 SNLYGSPGSIYIRQTSQSSSGRQTPQSTPWQSSPQGPV----PHYSQR-----PLPVYPH 271
           S+++G P ++ +    ++   +Q PQ  P Q +P GP     P + Q+         +  
Sbjct: 142 SSMWG-PRAVQVPDQIRAPYQQQQPQPQPPQPAPSGPPAQGHPQHMQQMGSYMARGDFSM 200

Query: 272 QQNYQP----SQYSPKQQQIPQS---------AYHSPPPSQCPSPFSSPQHQVQ-----P 313
           QQ+ QP    SQ+S  Q+ + Q           + S  P Q PS   S +H VQ     P
Sbjct: 201 QQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHHP 260

Query: 314 SQLGHIFMPPSPSTTPPHPYQQGPPSYQKQG-------------SHSVAYLPYTASSLSK 360
           S   H           P+P QQG    Q                ++S  Y  Y  S+L++
Sbjct: 261 STALHGESVAHSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQ 320

Query: 361 GSMKKIEITVEPSQRPGTAINRSPSPISNQ---PSPWNQHSLYTATTPPSSSPSRGIS-- 415
           G +    +         T +N+S     N    PS   Q  ++     PS S ++  +  
Sbjct: 321 GLVNNTGMNQNLGLTNNTPMNQSVPRYPNAVGFPSNSGQGLMHQQPIHPSGSLNQMNTQT 380

Query: 416 ---SQPKPPFSVNPVYITYTQPTGPSCTPSPSPR 446
              SQP+  ++  P        + P+ TP P  R
Sbjct: 381 MHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVR 414



 Score = 35.0 bits (79), Expect = 0.24
 Identities = 52/207 (25%), Positives = 73/207 (35%), Gaps = 40/207 (19%)

Query: 257 PVPHYSQRPLPVYPH------QQNYQPSQYSPKQQQ--IPQSAYHSPPPSQCPSPFSSPQ 308
           P   Y   P+P  PH      Q    P   + +  Q  +  S+   P   Q P    +P 
Sbjct: 101 PHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPY 160

Query: 309 HQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHSVAYLPYTASSLSKGSMKKIEI 368
            Q QP               PP P   GPP+   QG     ++    S +++G    ++ 
Sbjct: 161 QQQQPQP------------QPPQPAPSGPPA---QGHPQ--HMQQMGSYMARGDF-SMQQ 202

Query: 369 TVEPSQRPGTAINRSPSPISNQPSPWNQHSLYTATTPP---SSSPSRGISSQPKPPFSVN 425
             +P QR         S  S      NQ + + AT+ P   S  P +  S  P    SV 
Sbjct: 203 HGQPQQR--------MSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQ 254

Query: 426 PV-YITYTQPTGPSCTPSPSPRVIPNP 451
              +   T   G S   + SPR  PNP
Sbjct: 255 QFHHHPSTALHGESV--AHSPRFSPNP 279


>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
          Length = 2285

 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 114/464 (24%), Positives = 170/464 (36%), Gaps = 67/464 (14%)

Query: 79  HSPSSYHPGDGAQLNGGRTLVHSSSD-------GHIDPQHAAGKQLICLVQEPHSAPA-- 129
           H+P S     G+   GG+ L  +          G + PQ   G       Q P S P   
Sbjct: 359 HAPMS----PGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQG 414

Query: 130 -------VVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSP---PP 179
                    + TP   P  M  + +SA    S   Q P   Q G +    QG +P     
Sbjct: 415 HGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQ 474

Query: 180 PPPSYMHIPRYSTNPITVTVSQNLPSGQTVPRALQILPQIPSNL--YGSPGSIYIRQTS- 236
            P      P YS  P + T     PS Q  P++    PQ+ S+   Y    S    Q S 
Sbjct: 475 SPHPQQQQPPYSQQPPSQTPHAQ-PSYQQQPQSQP--PQLQSSQPPYSQQPSQPPHQQSP 531

Query: 237 -----QSSSGRQTPQSTPWQSSPQGPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQIPQSA 291
                Q S+ +Q PQS P  S PQ   P+  Q+P    P   + Q +   P+ QQ  Q+A
Sbjct: 532 APYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTA 591

Query: 292 YHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHSVAYL 351
           Y             S Q    P +L         S+ P     +G    Q+  + S+   
Sbjct: 592 Y-------------SQQRFPPPQELSQDSFGSQASSAPSMTSSKGG---QEDMNLSLQSR 635

Query: 352 PYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQPSPWNQHSLYTATTPPSSSPS 411
           P +   LS GS+  + +  E +  PG + +   S    Q +P    S ++  T P     
Sbjct: 636 PSSLPDLS-GSIDDLPMGTEGALSPGVSTSGISSSQGEQSNP--AQSPFSPHTSPHLPGI 692

Query: 412 RGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTTVFKITV--------GRAT 463
           RG S  P P  S   V  + + P  P+    P  ++ P P +    ++          A 
Sbjct: 693 RGPS--PSPVGSPASVAQSRSGPLSPAAV--PGNQMPPRPPSGQSDSIMHPSMNQSSIAQ 748

Query: 464 TENLLNLVDQEERSAAPEPIQPISVIPGSGGE--KGSHKYQRSS 505
               +    Q  + ++P+P   +S    SGG+   G   YQ++S
Sbjct: 749 DRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNS 792



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 98/409 (23%), Positives = 133/409 (32%), Gaps = 75/409 (18%)

Query: 84  YHPGDGAQLNGGRTLVHSSSDGHIDPQHAAGKQLICLVQEPHSAPAVVAATPN--YNPFF 141
           +H   G Q + G   + S   G ++P   AG Q     Q  H         PN  YN ++
Sbjct: 169 FHQQHGGQQSPGLAALQSGGGGGLEPY--AGPQ-----QNSHDH-----GFPNHQYNSYY 216

Query: 142 MNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPPPPPSYMHIPRYSTNPIT----- 196
            N     +A PP  P    SS + G   S     +   PPPS       S++        
Sbjct: 217 PNR----SAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFG 272

Query: 197 -------VTVSQNLPSGQTVPRALQIL--PQIPSNLYGSPGSIYI--RQTSQSSSGRQTP 245
                         P     P   Q+L  P       G PG  Y    Q   +  G    
Sbjct: 273 AMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADM 332

Query: 246 QSTPWQSSPQGPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQIPQSAYHSPPPSQCPSPFS 305
            S  W ++        +        H     P            S     P ++ P P S
Sbjct: 333 ASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPG----------SSGGGGQPLARTPQP-S 381

Query: 306 SPQHQVQPSQLGHIFMPPSP-STTPPHPYQQGPPSYQKQ---------GSHSVAYLPYTA 355
           SP  Q+         M P P   T P+  QQGPPS  +Q         GS +    P T 
Sbjct: 382 SPMDQMGK-------MRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTM 434

Query: 356 SSLSKGSMKKIEITVE----PSQRPGTAINRSPSPISNQ--PSPWNQHSLYTATTP---P 406
              ++ +M  +  T +      Q P     +  +P  NQ  P P  Q   Y+   P   P
Sbjct: 435 QGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTP 494

Query: 407 SSSPSRGISSQPKPP--FSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            + PS     Q +PP   S  P Y    QP+ P    SP+P      TT
Sbjct: 495 HAQPSYQQQPQSQPPQLQSSQPPY--SQQPSQPPHQQSPAPYPSQQSTT 541



 Score = 43.1 bits (100), Expect = 9e-04
 Identities = 81/352 (23%), Positives = 136/352 (38%), Gaps = 47/352 (13%)

Query: 145  QNRSAATPPSQPPQQPSSMQTGMNPSAMQGP-SPPPPPPSYMHIPRYSTNPITVTVSQNL 203
            Q R++ TP   P  QPS     MN S M G  S  P    Y  + +   +   ++  Q  
Sbjct: 1200 QKRNSMTP--NPGYQPS-----MNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFMSSGQGP 1252

Query: 204  PSGQTVPRALQILPQIPSNLYGSP-----GSIYIRQTSQSSSGRQTPQSTPWQSSPQGPV 258
              G   P +    P + +   G       G  Y R  ++   G +   ST        P 
Sbjct: 1253 NGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTG------APQ 1306

Query: 259  PHYSQRPLPVYPHQQNYQPSQYSPKQQQIPQSAYHSPPPSQCPSPFSSPQHQVQPSQLGH 318
            P+     +P  P    Y PS+Y P+QQQ  Q   H    +Q  S   +P     PSQ   
Sbjct: 1307 PNL----MPSNPDSGMYSPSRYPPQQQQ-QQQQRHDSYGNQF-STQGTPSGSPFPSQQTT 1360

Query: 319  IFMPPSPSTTPPHPYQQGPPSYQKQGS-HSVAYLPYTASSLSKGSMKKIEITVEPSQRPG 377
            ++     +   P     GPP+ + +G  +SV Y      S  +G  ++ ++   P  +P 
Sbjct: 1361 MYQQQQQNYKRPMDGTYGPPAKRHEGEMYSVPY------STGQGQPQQQQL---PPAQPQ 1411

Query: 378  TAINRSPSPISNQPSPWNQH-SLY--TATTPPSSSPSRGISSQPKPPFSVNPVYITYTQP 434
             A  +  +  S Q   +NQ+ + Y  TAT      P+ G  +Q    F  + V    + P
Sbjct: 1412 PASQQQAAQPSPQQDVYNQYGNAYPATATAATERRPAGGPQNQFPFQFGRDRV----SAP 1467

Query: 435  TGPSCTPSPSPRVIPNP-----TTVFKITVGRATTENLLNLVDQEERSAAPE 481
             G +   +  P+++  P         + T+ +   +   N  +++   +AP+
Sbjct: 1468 PGTNAQQNMPPQMMGGPIQASAEVAQQGTMWQGRNDMTYNYANRQSTGSAPQ 1519



 Score = 35.0 bits (79), Expect = 0.24
 Identities = 68/325 (20%), Positives = 102/325 (31%), Gaps = 63/325 (19%)

Query: 74  INLGIHSPSSYHPGDGAQLNGGRTLVHSSSDGHIDPQHAAGKQLICLVQEPHSAPAVVAA 133
           +NL + S  S  P     L+G    +   ++G + P        I   Q   S PA    
Sbjct: 628 MNLSLQSRPSSLP----DLSGSIDDLPMGTEGALSP--GVSTSGISSSQGEQSNPAQSPF 681

Query: 134 TPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPPPPPS---------- 183
           +P+ +P     +  S + P   P     S    ++P+A+ G   PP PPS          
Sbjct: 682 SPHTSPHLPGIRGPSPS-PVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPS 740

Query: 184 -----------YMH----IPRYSTNPITVTVSQNLPSGQTVPRALQILPQIPSNLYGSPG 228
                      YM     +P+YS+      +S   PSG  +   +    Q     YG  G
Sbjct: 741 MNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQG 800

Query: 229 SIYIRQ-----------------TSQSSSGRQTPQSTPWQSSPQGPVPHYSQRPLPVYPH 271
             Y  Q                  S   +G   P     Q   Q  +P Y   P P    
Sbjct: 801 GQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQPGIPPYGTLP-PGRMS 859

Query: 272 QQNYQPSQYSPKQQQIPQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPH 331
             +     Y P    +P           CP P    +   + +   H+      +  P +
Sbjct: 860 HASMGNRPYGPNMANMPPQV----GSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGY 915

Query: 332 PYQQ-------GPPSYQKQGSHSVA 349
           P          GPP    QG +S+A
Sbjct: 916 PNMNQGGMMGTGPP--YGQGINSMA 938



 Score = 30.4 bits (67), Expect = 5.9
 Identities = 60/255 (23%), Positives = 84/255 (32%), Gaps = 73/255 (28%)

Query: 145  QNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPPPPPSYMHIPRYSTNPITVTVS-QNL 203
            Q +    PP+QP  QP+S Q    PS  Q           ++    +  P T T + +  
Sbjct: 1399 QPQQQQLPPAQP--QPASQQQAAQPSPQQD----------VYNQYGNAYPATATAATERR 1446

Query: 204  PSGQ--------------TVPRALQILPQIPSNLYGSP--GSIYIRQTSQSSSGRQ---- 243
            P+G               + P        +P  + G P   S  + Q      GR     
Sbjct: 1447 PAGGPQNQFPFQFGRDRVSAPPGTNAQQNMPPQMMGGPIQASAEVAQQGTMWQGRNDMTY 1506

Query: 244  ---TPQSTPWQSSPQGPVPHYSQRPLPVYPHQQN----------------YQPSQYSPKQ 284
                 QST   S+PQGP  H   R   +    Q                 Y PS   P  
Sbjct: 1507 NYANRQSTG--SAPQGPAYHGVNRTDEMLHTDQRANHEGSWPSHGTRQPPYGPSAPVPPM 1564

Query: 285  QQIPQSAYHSPPPSQ-------CPSPFSSP-QHQVQPSQLGHIFM--------PPSP-ST 327
             + P S Y  PP  Q        P+P   P +++  PS+   +          PP P S 
Sbjct: 1565 TRPPPSNYQPPPSMQNHIPQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPVPASH 1624

Query: 328  TPPHPYQQGPPSYQK 342
              P P Q  PP  ++
Sbjct: 1625 IAPAPVQ--PPMIRR 1637


>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
          Length = 2068

 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 114/464 (24%), Positives = 170/464 (36%), Gaps = 67/464 (14%)

Query: 79  HSPSSYHPGDGAQLNGGRTLVHSSSD-------GHIDPQHAAGKQLICLVQEPHSAPA-- 129
           H+P S     G+   GG+ L  +          G + PQ   G       Q P S P   
Sbjct: 359 HAPMS----PGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQG 414

Query: 130 -------VVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSP---PP 179
                    + TP   P  M  + +SA    S   Q P   Q G +    QG +P     
Sbjct: 415 HGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQ 474

Query: 180 PPPSYMHIPRYSTNPITVTVSQNLPSGQTVPRALQILPQIPSNL--YGSPGSIYIRQTS- 236
            P      P YS  P + T     PS Q  P++    PQ+ S+   Y    S    Q S 
Sbjct: 475 SPHPQQQQPPYSQQPPSQTPHAQ-PSYQQQPQSQP--PQLQSSQPPYSQQPSQPPHQQSP 531

Query: 237 -----QSSSGRQTPQSTPWQSSPQGPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQIPQSA 291
                Q S+ +Q PQS P  S PQ   P+  Q+P    P   + Q +   P+ QQ  Q+A
Sbjct: 532 APYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTA 591

Query: 292 YHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHSVAYL 351
           Y             S Q    P +L         S+ P     +G    Q+  + S+   
Sbjct: 592 Y-------------SQQRFPPPQELSQDSFGSQASSAPSMTSSKGG---QEDMNLSLQSR 635

Query: 352 PYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQPSPWNQHSLYTATTPPSSSPS 411
           P +   LS GS+  + +  E +  PG + +   S    Q +P    S ++  T P     
Sbjct: 636 PSSLPDLS-GSIDDLPMGTEGALSPGVSTSGISSSQGEQSNP--AQSPFSPHTSPHLPGI 692

Query: 412 RGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTTVFKITV--------GRAT 463
           RG S  P P  S   V  + + P  P+    P  ++ P P +    ++          A 
Sbjct: 693 RGPS--PSPVGSPASVAQSRSGPLSPAAV--PGNQMPPRPPSGQSDSIMHPSMNQSSIAQ 748

Query: 464 TENLLNLVDQEERSAAPEPIQPISVIPGSGGE--KGSHKYQRSS 505
               +    Q  + ++P+P   +S    SGG+   G   YQ++S
Sbjct: 749 DRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNS 792



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 98/409 (23%), Positives = 133/409 (32%), Gaps = 75/409 (18%)

Query: 84  YHPGDGAQLNGGRTLVHSSSDGHIDPQHAAGKQLICLVQEPHSAPAVVAATPN--YNPFF 141
           +H   G Q + G   + S   G ++P   AG Q     Q  H         PN  YN ++
Sbjct: 169 FHQQHGGQQSPGLAALQSGGGGGLEPY--AGPQ-----QNSHDH-----GFPNHQYNSYY 216

Query: 142 MNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPPPPPSYMHIPRYSTNPIT----- 196
            N     +A PP  P    SS + G   S     +   PPPS       S++        
Sbjct: 217 PNR----SAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFG 272

Query: 197 -------VTVSQNLPSGQTVPRALQIL--PQIPSNLYGSPGSIYI--RQTSQSSSGRQTP 245
                         P     P   Q+L  P       G PG  Y    Q   +  G    
Sbjct: 273 AMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADM 332

Query: 246 QSTPWQSSPQGPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQIPQSAYHSPPPSQCPSPFS 305
            S  W ++        +        H     P            S     P ++ P P S
Sbjct: 333 ASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPG----------SSGGGGQPLARTPQP-S 381

Query: 306 SPQHQVQPSQLGHIFMPPSP-STTPPHPYQQGPPSYQKQ---------GSHSVAYLPYTA 355
           SP  Q+         M P P   T P+  QQGPPS  +Q         GS +    P T 
Sbjct: 382 SPMDQMGK-------MRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTM 434

Query: 356 SSLSKGSMKKIEITVE----PSQRPGTAINRSPSPISNQ--PSPWNQHSLYTATTP---P 406
              ++ +M  +  T +      Q P     +  +P  NQ  P P  Q   Y+   P   P
Sbjct: 435 QGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTP 494

Query: 407 SSSPSRGISSQPKPP--FSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
            + PS     Q +PP   S  P Y    QP+ P    SP+P      TT
Sbjct: 495 HAQPSYQQQPQSQPPQLQSSQPPY--SQQPSQPPHQQSPAPYPSQQSTT 541



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 69/323 (21%), Positives = 103/323 (31%), Gaps = 72/323 (22%)

Query: 149  AATPPSQPPQQPSSMQTGMNPSAMQGPSPPPPPPSYMH-----IPRYS-TNPITVTVSQN 202
            A +   Q PQ P S  + M   A  G   PP P S  H     +P  S +N + +  + N
Sbjct: 1136 AGSGSMQGPQTPQSTSSSM---AEGGDLKPPTPASTPHSQIPPLPGMSRSNSVGIQDAFN 1192

Query: 203  LPSGQTVPRALQILP----QIPSNLYGSPGSI-YIRQTSQSSSGRQTPQSTPWQSSPQGP 257
              S  T  +   + P    Q   N     G + Y        S R+ P S P+ SS QGP
Sbjct: 1193 DGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFMSSGQGP 1252

Query: 258  ---------------VPHYSQRPLPVYPHQQNYQPSQYSPKQQQIPQSAYHSPPPSQCPS 302
                           + + +  P   YP+   Y   +  P        +  +P P+  PS
Sbjct: 1253 NGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAPQPNLMPS 1312

Query: 303  PFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHSVAYLPYTASSLSKGS 362
               S  +              SPS  PP   QQ    +   G+                 
Sbjct: 1313 NPDSGMY--------------SPSRYPPQQQQQQQQRHDSYGNQF--------------- 1343

Query: 363  MKKIEITVEPSQRPGTAINRSPSPISNQPSPWNQHSLYTATTPPSSSPSRGISSQPKPPF 422
                           T    S SP  +Q +   Q     ++  P   P    +S  K PF
Sbjct: 1344 --------------STQGTPSGSPFPSQQTTMYQQQQQVSSPAPLPRPMENRTSPSKSPF 1389

Query: 423  SVNPVYITYTQPTGPSCTPSPSP 445
              + + +    P  P+   +P+P
Sbjct: 1390 LHSGMKMQKAGPPVPASHIAPAP 1412



 Score = 35.0 bits (79), Expect = 0.24
 Identities = 68/325 (20%), Positives = 102/325 (31%), Gaps = 63/325 (19%)

Query: 74  INLGIHSPSSYHPGDGAQLNGGRTLVHSSSDGHIDPQHAAGKQLICLVQEPHSAPAVVAA 133
           +NL + S  S  P     L+G    +   ++G + P        I   Q   S PA    
Sbjct: 628 MNLSLQSRPSSLP----DLSGSIDDLPMGTEGALSP--GVSTSGISSSQGEQSNPAQSPF 681

Query: 134 TPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPPPPPS---------- 183
           +P+ +P     +  S + P   P     S    ++P+A+ G   PP PPS          
Sbjct: 682 SPHTSPHLPGIRGPSPS-PVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPS 740

Query: 184 -----------YMH----IPRYSTNPITVTVSQNLPSGQTVPRALQILPQIPSNLYGSPG 228
                      YM     +P+YS+      +S   PSG  +   +    Q     YG  G
Sbjct: 741 MNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQG 800

Query: 229 SIYIRQ-----------------TSQSSSGRQTPQSTPWQSSPQGPVPHYSQRPLPVYPH 271
             Y  Q                  S   +G   P     Q   Q  +P Y   P P    
Sbjct: 801 GQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQPGIPPYGTLP-PGRMS 859

Query: 272 QQNYQPSQYSPKQQQIPQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPH 331
             +     Y P    +P           CP P    +   + +   H+      +  P +
Sbjct: 860 HASMGNRPYGPNMANMPPQV----GSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGY 915

Query: 332 PYQQ-------GPPSYQKQGSHSVA 349
           P          GPP    QG +S+A
Sbjct: 916 PNMNQGGMMGTGPP--YGQGINSMA 938



 Score = 33.9 bits (76), Expect = 0.54
 Identities = 60/252 (23%), Positives = 90/252 (35%), Gaps = 47/252 (18%)

Query: 145  QNRSAATPPSQPPQQPSSMQTGMNPSAMQGP-SPPPPPPSYMHIPRYSTNPITVTVSQNL 203
            Q R++ TP   P  QPS     MN S M G  S  P    Y  + +   +   ++  Q  
Sbjct: 1200 QKRNSMTP--NPGYQPS-----MNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFMSSGQGP 1252

Query: 204  PSGQTVPRALQILPQIPSNLYGSP-----GSIYIRQTSQSSSGRQTPQSTPWQSSPQGPV 258
              G   P +    P + +   G       G  Y R  ++   G +   ST        P 
Sbjct: 1253 NGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTG------APQ 1306

Query: 259  PHYSQRPLPVYPHQQNYQPSQYSPKQQQIPQSAYHSPPPSQCPSPFSSPQHQVQPSQLGH 318
            P+     +P  P    Y PS+Y P+QQQ                     Q Q +    G+
Sbjct: 1307 PNL----MPSNPDSGMYSPSRYPPQQQQ---------------------QQQQRHDSYGN 1341

Query: 319  IFMPPSPSTTPPHPYQQGPPSYQKQGSHSVAYLP---YTASSLSKGSMKKIEITVEPSQR 375
             F      +  P P QQ     Q+Q   S A LP      +S SK       + ++ +  
Sbjct: 1342 QFSTQGTPSGSPFPSQQTTMYQQQQQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGP 1401

Query: 376  PGTAINRSPSPI 387
            P  A + +P+P+
Sbjct: 1402 PVPASHIAPAPV 1413


>gi|55750053 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 131/605 (21%), Positives = 193/605 (31%), Gaps = 167/605 (27%)

Query: 78  IHSPSSYHPGDGAQLNGGRTLVHSSSDGHIDPQHAAGKQLICLVQEPHSAPAVVAATPNY 137
           +++ S+  PG GAQ             GH+   HA G+ +  L   P   P +  +    
Sbjct: 310 LNNASASPPGLGAQ----------PLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPS---- 355

Query: 138 NPFFMNEQNRSAATPPSQ-PPQQPSSMQTGMNPSAMQGPSPPPPPPSYMHIPRYSTN--- 193
            P  +   + SA  PP + P    SS     + S+    S   P P+   +P Y  +   
Sbjct: 356 -PHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPP 414

Query: 194 PITVTVSQNLPSGQTVPRALQILPQIPSNLYGSPGSI----YIRQTSQSSSGRQT-PQST 248
           P +++VS   P            P +PS    S G      Y R  + S++     P ST
Sbjct: 415 PTSLSVSNQPPK--------YTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPST 466

Query: 249 PWQSSPQGPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQIPQSAYHS----PPPSQCPSPF 304
             QS+   PV  +       + H Q  Q  Q   +QQQ  Q  +H     PPP   P P 
Sbjct: 467 GAQSTAHPPVSTH-------HHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPL 519

Query: 305 SS------------------------------PQHQVQPSQLGHIFMP------------ 322
                                           P  QV  SQ G    P            
Sbjct: 520 EGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTS 579

Query: 323 --------PSPSTTP---PHPYQQ-------------------------------GPPSY 340
                   PSPS  P   P+P+                                 GPP Y
Sbjct: 580 QGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPY 639

Query: 341 QKQGSHSVAYLPYTASSLSKGSMKKIEITVEPSQR-------PGTAINRSPSPISNQPSP 393
            K+     AY   T      GS         P  R       PGT    SP+ +   P P
Sbjct: 640 GKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPT-VGPGPLP 698

Query: 394 WNQHSLYTATTPPSSSPSRGISSQPKPPFSVNPV-------YITYTQPTGPSCTPSPSPR 446
               S   +  PP ++P+ G      PP S   +       Y T   P  P+ +PSP P+
Sbjct: 699 PAGPSGLPSLPPPPAAPASG------PPLSATQIKQEPAEEYETPESPVPPARSPSPPPK 752

Query: 447 VIPNPTTVFKITVGRATTENLLNLVDQEERSAAPEPIQPISVIPGSGGEKGSHKYQRSSS 506
           V+  P+         + +      +D+   S A   +  + +      +K +   ++   
Sbjct: 753 VVDVPSHA-------SQSARFNKHLDRGFNSCARSDLYFVPLEGSKLAKKRADLVEKVRR 805

Query: 507 SGSDDYAYTQALLLHQRARMERLAKQLKLEKEELERLKSEVNGMEHDLMQRRLRRVSCTT 566
                          QRAR E+  ++ +  ++E ER K         L Q     V C +
Sbjct: 806 EAE------------QRAREEKEREREREREKEREREKERELERSVKLAQEGRAPVECPS 853

Query: 567 AIPTP 571
             P P
Sbjct: 854 LGPVP 858



 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 77/297 (25%), Positives = 102/297 (34%), Gaps = 41/297 (13%)

Query: 152 PPSQPPQQPSSMQTGMNPSAMQGPSPPPPPPSYMHIPRYSTNPITVTVSQNLPSGQTVPR 211
           PP  PP       T   P A   P P   P  Y H P     P T  + Q  P G   P 
Sbjct: 162 PPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGY-HAP---MEPPTSRMFQ-APPGAPPPH 216

Query: 212 ALQILPQIPSNLYGSP-----GSIYIRQTSQSSSGRQ-TPQSTPWQSSPQGPVPHYSQRP 265
             Q+ P     +   P     G          + G+Q  P +TP   S  G       +P
Sbjct: 217 P-QLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKP 275

Query: 266 LPVYPHQQNYQPSQYSPKQQQIPQSAYHSPPP---------SQCPSPFSS---PQHQVQP 313
            P  P      PS  +P     P    + PPP         S  P    +   P H   P
Sbjct: 276 -PTTPVGGGNLPS--APPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSP 332

Query: 314 SQLGHIF--MPPSPSTTP---PHPYQQGPPSYQKQGSHSVAYLPYTASSLSKGSMKKIEI 368
             +G     +PP P   P   P P+   PP+     +  + + PY++SS S  +      
Sbjct: 333 HAMGQGMGGLPPGPEKGPTLAPSPHSL-PPASSSAPAPPMRF-PYSSSSSSSAAASSSSS 390

Query: 369 TVEPSQRPGTAINRSPSPISNQPSPWNQHSLYTATTPPS----SSPSRGISSQPKPP 421
           +   S  P  A    PS   + P P    SL  +  PP     S PS+ + SQ  PP
Sbjct: 391 SSSSSASPFPASQALPSYPHSFPPP---TSLSVSNQPPKYTQPSLPSQAVWSQGPPP 444



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 84/359 (23%), Positives = 110/359 (30%), Gaps = 74/359 (20%)

Query: 194 PITVTVSQNLPSGQTVPRALQILPQIPSNLYGSPGSIYIRQTSQSSSGR-QTPQSTPWQS 252
           P      Q LP  Q+ P  L  L     N  GS     I Q ++S+S    +P S    S
Sbjct: 87  PKKTKTEQELPRPQS-PSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDS 145

Query: 253 SPQGPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQIPQSAYHSPPPSQCPSPFSSP--QHQ 310
                +     RP         Y P    P   Q P S    P  S  P P  +P   H 
Sbjct: 146 DSSSGLSQGPARP---------YHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHA 196

Query: 311 VQPSQLGHIFMPPSPSTTPPHP---------YQQGPPSYQKQGSHSVAY----------L 351
                   +F  P P   PPHP            GPP   K G  + +            
Sbjct: 197 PMEPPTSRMFQAP-PGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPP 255

Query: 352 PYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQPSPWNQHSLYTATTPPSSSPS 411
           P T  S+S         T  P+   G     S  P +N P     H       PP+  P 
Sbjct: 256 PTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFP-----HVTPNLPPPPALRPL 310

Query: 412 R-------GISSQPKPPFSVNPVYITYTQ---PTGPSCTP--SPSPRVIPNPTTVFKITV 459
                   G+ +QP P    +P  +       P GP   P  +PSP  +P  +       
Sbjct: 311 NNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPAS------- 363

Query: 460 GRATTENLLNLVDQEERSAAPEPIQPISVIPGSGGEKGSHKYQRSSSSGSDDYAYTQAL 518
                            S+AP P         S     +     SSSS +  +  +QAL
Sbjct: 364 -----------------SSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQAL 405


>gi|55750041 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 131/605 (21%), Positives = 193/605 (31%), Gaps = 167/605 (27%)

Query: 78  IHSPSSYHPGDGAQLNGGRTLVHSSSDGHIDPQHAAGKQLICLVQEPHSAPAVVAATPNY 137
           +++ S+  PG GAQ             GH+   HA G+ +  L   P   P +  +    
Sbjct: 310 LNNASASPPGLGAQ----------PLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPS---- 355

Query: 138 NPFFMNEQNRSAATPPSQ-PPQQPSSMQTGMNPSAMQGPSPPPPPPSYMHIPRYSTN--- 193
            P  +   + SA  PP + P    SS     + S+    S   P P+   +P Y  +   
Sbjct: 356 -PHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPP 414

Query: 194 PITVTVSQNLPSGQTVPRALQILPQIPSNLYGSPGSI----YIRQTSQSSSGRQT-PQST 248
           P +++VS   P            P +PS    S G      Y R  + S++     P ST
Sbjct: 415 PTSLSVSNQPPK--------YTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPST 466

Query: 249 PWQSSPQGPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQIPQSAYHS----PPPSQCPSPF 304
             QS+   PV  +       + H Q  Q  Q   +QQQ  Q  +H     PPP   P P 
Sbjct: 467 GAQSTAHPPVSTH-------HHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPL 519

Query: 305 SS------------------------------PQHQVQPSQLGHIFMP------------ 322
                                           P  QV  SQ G    P            
Sbjct: 520 EGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTS 579

Query: 323 --------PSPSTTP---PHPYQQ-------------------------------GPPSY 340
                   PSPS  P   P+P+                                 GPP Y
Sbjct: 580 QGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPY 639

Query: 341 QKQGSHSVAYLPYTASSLSKGSMKKIEITVEPSQR-------PGTAINRSPSPISNQPSP 393
            K+     AY   T      GS         P  R       PGT    SP+ +   P P
Sbjct: 640 GKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPT-VGPGPLP 698

Query: 394 WNQHSLYTATTPPSSSPSRGISSQPKPPFSVNPV-------YITYTQPTGPSCTPSPSPR 446
               S   +  PP ++P+ G      PP S   +       Y T   P  P+ +PSP P+
Sbjct: 699 PAGPSGLPSLPPPPAAPASG------PPLSATQIKQEPAEEYETPESPVPPARSPSPPPK 752

Query: 447 VIPNPTTVFKITVGRATTENLLNLVDQEERSAAPEPIQPISVIPGSGGEKGSHKYQRSSS 506
           V+  P+         + +      +D+   S A   +  + +      +K +   ++   
Sbjct: 753 VVDVPSHA-------SQSARFNKHLDRGFNSCARSDLYFVPLEGSKLAKKRADLVEKVRR 805

Query: 507 SGSDDYAYTQALLLHQRARMERLAKQLKLEKEELERLKSEVNGMEHDLMQRRLRRVSCTT 566
                          QRAR E+  ++ +  ++E ER K         L Q     V C +
Sbjct: 806 EAE------------QRAREEKEREREREREKEREREKERELERSVKLAQEGRAPVECPS 853

Query: 567 AIPTP 571
             P P
Sbjct: 854 LGPVP 858



 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 77/297 (25%), Positives = 102/297 (34%), Gaps = 41/297 (13%)

Query: 152 PPSQPPQQPSSMQTGMNPSAMQGPSPPPPPPSYMHIPRYSTNPITVTVSQNLPSGQTVPR 211
           PP  PP       T   P A   P P   P  Y H P     P T  + Q  P G   P 
Sbjct: 162 PPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGY-HAP---MEPPTSRMFQ-APPGAPPPH 216

Query: 212 ALQILPQIPSNLYGSP-----GSIYIRQTSQSSSGRQ-TPQSTPWQSSPQGPVPHYSQRP 265
             Q+ P     +   P     G          + G+Q  P +TP   S  G       +P
Sbjct: 217 P-QLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKP 275

Query: 266 LPVYPHQQNYQPSQYSPKQQQIPQSAYHSPPP---------SQCPSPFSS---PQHQVQP 313
            P  P      PS  +P     P    + PPP         S  P    +   P H   P
Sbjct: 276 -PTTPVGGGNLPS--APPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSP 332

Query: 314 SQLGHIF--MPPSPSTTP---PHPYQQGPPSYQKQGSHSVAYLPYTASSLSKGSMKKIEI 368
             +G     +PP P   P   P P+   PP+     +  + + PY++SS S  +      
Sbjct: 333 HAMGQGMGGLPPGPEKGPTLAPSPHSL-PPASSSAPAPPMRF-PYSSSSSSSAAASSSSS 390

Query: 369 TVEPSQRPGTAINRSPSPISNQPSPWNQHSLYTATTPPS----SSPSRGISSQPKPP 421
           +   S  P  A    PS   + P P    SL  +  PP     S PS+ + SQ  PP
Sbjct: 391 SSSSSASPFPASQALPSYPHSFPPP---TSLSVSNQPPKYTQPSLPSQAVWSQGPPP 444



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 84/359 (23%), Positives = 110/359 (30%), Gaps = 74/359 (20%)

Query: 194 PITVTVSQNLPSGQTVPRALQILPQIPSNLYGSPGSIYIRQTSQSSSGR-QTPQSTPWQS 252
           P      Q LP  Q+ P  L  L     N  GS     I Q ++S+S    +P S    S
Sbjct: 87  PKKTKTEQELPRPQS-PSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDS 145

Query: 253 SPQGPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQIPQSAYHSPPPSQCPSPFSSP--QHQ 310
                +     RP         Y P    P   Q P S    P  S  P P  +P   H 
Sbjct: 146 DSSSGLSQGPARP---------YHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHA 196

Query: 311 VQPSQLGHIFMPPSPSTTPPHP---------YQQGPPSYQKQGSHSVAY----------L 351
                   +F  P P   PPHP            GPP   K G  + +            
Sbjct: 197 PMEPPTSRMFQAP-PGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPP 255

Query: 352 PYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQPSPWNQHSLYTATTPPSSSPS 411
           P T  S+S         T  P+   G     S  P +N P     H       PP+  P 
Sbjct: 256 PTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFP-----HVTPNLPPPPALRPL 310

Query: 412 R-------GISSQPKPPFSVNPVYITYTQ---PTGPSCTP--SPSPRVIPNPTTVFKITV 459
                   G+ +QP P    +P  +       P GP   P  +PSP  +P  +       
Sbjct: 311 NNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPAS------- 363

Query: 460 GRATTENLLNLVDQEERSAAPEPIQPISVIPGSGGEKGSHKYQRSSSSGSDDYAYTQAL 518
                            S+AP P         S     +     SSSS +  +  +QAL
Sbjct: 364 -----------------SSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQAL 405


>gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo
            sapiens]
          Length = 1636

 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 96/378 (25%), Positives = 131/378 (34%), Gaps = 80/378 (21%)

Query: 122  QEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPPP- 180
            +E  S P  + A P     F+      +ATP   PP  P    TG  P  + GP PP   
Sbjct: 743  EELRSLPPDMVAGPRLPDTFLG-----SATPLHFPPS-PFPSSTGPGPHYLSGPLPPGTY 796

Query: 181  -PPSYMHIPRYSTNPITVTVSQNLPSGQTVPRALQILPQIP--SNLYGSPGSIYIRQTSQ 237
              P+ +  PR +  P  + V+   P+    P     L  +P  S  +G   S Y+     
Sbjct: 797  SGPTQLIQPR-APGPHAMPVAPG-PALYPAPAYTPELGLVPRSSPQHGVVSSPYVG---- 850

Query: 238  SSSGRQTPQSTPWQSSPQGPVPHYSQRPL-----PVYPHQQNYQ---PSQYSPKQQQIPQ 289
                     + P    P  P P +S   L     P      + Q   PS  +P+    P 
Sbjct: 851  ------VGPAPPVAGLPSAPPPQFSGPELAMAVRPATTTVDSIQAPIPSHTAPRPNPTPA 904

Query: 290  S---AYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTP-------PHPYQQGPPS 339
                 +  PPP   P+P++ P    QP    H F    P+  P       P P+ Q  PS
Sbjct: 905  PPPPCFPVPPPQPLPTPYTYPAGAKQPIPAQHHFSSGIPAGFPAPRIGPQPQPHPQPHPS 964

Query: 340  YQKQGSHSVAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQPSPWNQ--H 397
                       LP     L             P Q PG    +SP P + QP    Q   
Sbjct: 965  QAFGPQPPQQPLPLQHPHLF------------PPQAPGLLPPQSPYPYAPQPGVLGQPPP 1012

Query: 398  SLYTATTP-------PSSS-----PSRGISSQPKPPFSVNPVYITYTQPTGPSCTP---- 441
             L+T   P       P+ S     PS G    P PP +  P     T+P GP   P    
Sbjct: 1013 PLHTQLYPGPAQDPLPAHSGALPFPSPGPPQPPHPPLAYGPA--PSTRPMGPQAAPLTIR 1070

Query: 442  --------SPSPRVIPNP 451
                    +PSP ++P+P
Sbjct: 1071 GPSSAGQSTPSPHLVPSP 1088



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 65/249 (26%), Positives = 87/249 (34%), Gaps = 34/249 (13%)

Query: 150  ATPPSQPPQQPSSMQTGMNPSAMQGPSPPPPPPSYMHIPRYSTNPITVTVSQNLPSGQTV 209
            AT      Q P    T   P+    P+P PPPP +            V   Q LP+  T 
Sbjct: 880  ATTTVDSIQAPIPSHTAPRPN----PTPAPPPPCF-----------PVPPPQPLPTPYTY 924

Query: 210  PRALQILPQIPSNLYGSPGSIYIRQTSQSSSGRQTPQSTPWQSSPQGPVPHYSQRPLPV- 268
            P   +    IP+  + S G I     +     +  P   P  S   GP P   Q+PLP+ 
Sbjct: 925  PAGAK--QPIPAQHHFSSG-IPAGFPAPRIGPQPQPHPQPHPSQAFGPQP--PQQPLPLQ 979

Query: 269  YPHQQNYQPSQYSPKQQQIPQS----AYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMP-P 323
            +PH    Q     P Q   P +        PPP      +  P     P+  G +  P P
Sbjct: 980  HPHLFPPQAPGLLPPQSPYPYAPQPGVLGQPPPPLHTQLYPGPAQDPLPAHSGALPFPSP 1039

Query: 324  SPSTTPPHPYQQGP-PSYQKQGSHSVAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINR 382
             P   P  P   GP PS +  G       P  A    +G     + T  P   P  A + 
Sbjct: 1040 GPPQPPHPPLAYGPAPSTRPMG-------PQAAPLTIRGPSSAGQSTPSPHLVPSPAPSP 1092

Query: 383  SPSPISNQP 391
             P P+  +P
Sbjct: 1093 GPGPVPPRP 1101



 Score = 38.5 bits (88), Expect = 0.022
 Identities = 61/284 (21%), Positives = 91/284 (32%), Gaps = 83/284 (29%)

Query: 177 PPPPPPSYMHIPRYSTNPITVTVSQNLPSGQTVPRALQILPQIPSNLYGSPGSIYIRQTS 236
           PPP P +   +         V         +++P  +   P++P    GS   ++     
Sbjct: 716 PPPRPTAPKPLLPRREESEAVEAGDPPEELRSLPPDMVAGPRLPDTFLGSATPLHF---- 771

Query: 237 QSSSGRQTPQSTPWQSSPQGPVPHYSQRPLPVYPHQ---QNYQPSQYSPKQQQIPQSAYH 293
                      +P+ SS  GP PHY   PLP   +    Q  QP    P    +      
Sbjct: 772 ---------PPSPFPSST-GPGPHYLSGPLPPGTYSGPTQLIQPRAPGPHAMPVAPGPAL 821

Query: 294 SPPPSQCPS----PFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHSVA 349
            P P+  P     P SSPQH V  S    +   P  +  P  P    PP +         
Sbjct: 822 YPAPAYTPELGLVPRSSPQHGVVSSPYVGVGPAPPVAGLPSAP----PPQF--------- 868

Query: 350 YLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQPSPWNQHSLYTATTPPSSS 409
                       S  ++ + V P+    T ++   +PI +              T P  +
Sbjct: 869 ------------SGPELAMAVRPAT---TTVDSIQAPIPSH-------------TAPRPN 900

Query: 410 PSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTT 453
           P+      P PP               P C P P P+ +P P T
Sbjct: 901 PT------PAPP---------------PPCFPVPPPQPLPTPYT 923


>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
            1 [Homo sapiens]
          Length = 1250

 Score = 64.3 bits (155), Expect = 4e-10
 Identities = 78/311 (25%), Positives = 108/311 (34%), Gaps = 39/311 (12%)

Query: 145  QNRSAATPPSQP----PQQPSSMQTGMNPSAMQGPSPPPPPPSYMHIPRYSTNPITVTVS 200
            Q + A   PS P    P  P  +    + + +  P+PPPPPP    +P  +     VT+ 
Sbjct: 727  QLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIP 786

Query: 201  QNLPSGQTVPRALQILPQIPS-------NLYGSPGSIYIRQTSQSSSGRQTPQSTPWQS- 252
                +    P   Q  P  P+            P S YI  +  +      P + P Q  
Sbjct: 787  APTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPAS-YIPPSPPTPPVPVPPPTLPKQQS 845

Query: 253  -------SPQGPVPHY-----SQRPLPVYPHQQNYQPSQYSPKQ--QQIPQSAYHSPPPS 298
                   SP  PVP       SQ P P  P     QP +  P     Q P +    P   
Sbjct: 846  FCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQ 905

Query: 299  QCPSPFSSPQHQVQPSQLGHIFMPPSPS---TTPPHPYQQGPPSYQKQGSHSVAYLPYTA 355
                P  SP     P +   +F PP PS     PP P     P+  K GS        T+
Sbjct: 906  PSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPG----KKTS 961

Query: 356  SSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQPSPWNQHSLYTATTPPSSSPSRGIS 415
             + S G  K       P+ +  ++I  S      +P   +  SL +  TPP+ S S    
Sbjct: 962  KTSSPGGKKP-----PPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKE 1016

Query: 416  SQPKPPFSVNP 426
            + P P     P
Sbjct: 1017 TLPPPAAPPKP 1027



 Score = 63.2 bits (152), Expect = 8e-10
 Identities = 88/342 (25%), Positives = 115/342 (33%), Gaps = 48/342 (14%)

Query: 142 MNEQNR--SAATPPSQPPQQPSSMQTGMNPSAMQGPSPPPPPPSYMHIPRYSTNPITVTV 199
           M   NR  ++  PP  P  +  +  T   PS    P PPPPPP     P     P     
Sbjct: 595 MESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPP----PPPPPPPPPPLP 650

Query: 200 SQNLPS-GQTVP--------RALQILPQIPSNLYGSPGSIYIRQTSQSSSGRQTPQST-- 248
           SQ+ PS G   P          LQ   Q    L+  P    ++  S        P     
Sbjct: 651 SQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVP 710

Query: 249 PWQSSPQGPVPHYSQ---RPLPVYPHQQNYQPSQYSPKQQQIPQSAYHSPPPSQCPSPFS 305
           P    P  P P  +    +P P  P    +       K  Q+      +PP    P P  
Sbjct: 711 PPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIP 770

Query: 306 SP-QHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPS-------YQKQGSHSVAYLPYTASS 357
           +P   Q  P  L  I  P S  T  P   Q  PP+        +KQ +   +Y+P     
Sbjct: 771 APLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIP----- 825

Query: 358 LSKGSMKKIEITVEPSQRP---GTAINRSPSPISNQPSPWNQHSLYTATTPPSSSPSRGI 414
               S     + V P   P          PSP+S  PS   Q  + +   PP + P+  +
Sbjct: 826 ---PSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQ--IASQFPPPPTPPA--M 878

Query: 415 SSQPKPPFSVN-----PVYITYTQPTGPSCTPSPSPRVIPNP 451
            SQP  P   N     P  +       PS  P PSP   P P
Sbjct: 879 ESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPP 920



 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 80/312 (25%), Positives = 114/312 (36%), Gaps = 57/312 (18%)

Query: 124  PHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPPPPPS 183
            P S PAV  A P + P      +    +P   PP   SS+     P +     PPPPPP+
Sbjct: 892  PQSPPAV-KAKPKWQP-----SSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPT 945

Query: 184  YMHIPRYSTNPITVTVSQNLPSGQTVPRALQILPQIPSNLYGSPGSIYIRQTSQSSSGRQ 243
                P  S +P   T   + P G+  P      PQ  S++             +SSSG +
Sbjct: 946  ASPTPDKSGSPGKKTSKTSSPGGKKPPPT----PQRNSSI-------------KSSSGAE 988

Query: 244  TPQSTPWQSSPQGPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQIPQSAYHSPPPSQ--CP 301
             P+  P + S    V  ++       P ++   P    PK  ++  S  + P   Q  C 
Sbjct: 989  HPE--PKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCV 1046

Query: 302  S---------------PFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSH 346
            S                F SP     PS     F PP P T  P P  + P  +    S 
Sbjct: 1047 SAKAPVLSGRGKDSVVEFPSP-----PSDSD--FPPPPPETELPLPPIEIPAVFSGNTSP 1099

Query: 347  SVAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQPSPWNQHSLYTATTPP 406
             VA +       SK S+KK      P +   T + +  + IS QP      ++ T     
Sbjct: 1100 KVAVVNPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQ--AEISEQP------TMATVVPQV 1151

Query: 407  SSSPSRGISSQP 418
             +SP   +S QP
Sbjct: 1152 PTSPKSSLSVQP 1163


>gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]
          Length = 788

 Score = 63.5 bits (153), Expect = 6e-10
 Identities = 88/371 (23%), Positives = 126/371 (33%), Gaps = 55/371 (14%)

Query: 233 RQTSQSSSGRQTPQSTPWQSSPQGPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQIPQSAY 292
           +Q  Q +   Q P   P    PQ P      + L    H Q++QP    P Q Q P  A 
Sbjct: 257 QQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQP----PPQPQQPPVAQ 312

Query: 293 HSP---PPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHSVA 349
           + P   PP     P  S Q Q  P Q+ +   PP      P   QQ P   Q Q   +  
Sbjct: 313 NQPSQLPPQSQTQPLVS-QAQALPGQMLYT-QPPLKFVRAPMVVQQPPVQPQVQQQQTAV 370

Query: 350 YLPYTASSLSKGSMKKIEITVEPSQR------PGTAINRSPS------------------ 385
                A  ++ G     E   +          P TA++  PS                  
Sbjct: 371 QTAQAAQMVAPGVQMITEALAQGGMHIRARFPPTTAVSAIPSSSIPLGRQPMAQVSQSSL 430

Query: 386 PISNQPSPWNQ-HSLYTATTPPSSSPSRG-ISSQPKPPFSVNPVYITYTQPTGPSCTPSP 443
           P+ + PSP  Q  +  +   PP  SP  G  SSQP    S  P       P+  S  PSP
Sbjct: 431 PMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPA------PSPSSFLPSP 484

Query: 444 SPRVIPNPTTVFKITVGRATTENLLNLVDQEERSAAPEPIQPISVIPGSGGEKGSHKYQR 503
           SP+   +P T         T +N               P+ P SV+  +G  +   +   
Sbjct: 485 SPQPSQSPVTA-------RTPQNF----SVPSPGPLNTPVNPSSVMSPAGSSQAEEQQYL 533

Query: 504 SSSSGSDDYAYTQALLLHQRARMERLAKQLKLEKEELERLKSEVNGMEHDLMQR---RLR 560
                   Y      ++++  + E   K L   K  L+ L           +Q+    L 
Sbjct: 534 DKLKQLSKYIEPLRRMINKIDKNEDRKKDLSKMKSLLDILTDPSKRCPLKTLQKCEIALE 593

Query: 561 RVSCTTAIPTP 571
           ++    A+PTP
Sbjct: 594 KLKNDMAVPTP 604



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 80/288 (27%), Positives = 95/288 (32%), Gaps = 56/288 (19%)

Query: 152 PPSQPPQQPSSMQTGMNPSAMQGPSPPPPPPSYMHIPRYSTNPITVTVSQNLPSGQTVPR 211
           PP Q PQ P S         M       PPP     P     P     SQ  P  QT P 
Sbjct: 273 PPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQP-----SQLPPQSQTQPL 327

Query: 212 ALQILPQIPSNLYGSPGSIYIR------------QTSQSSSGRQTPQSTPW--------- 250
             Q        LY  P   ++R            Q  Q  +  QT Q+            
Sbjct: 328 VSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQMIT 387

Query: 251 QSSPQGPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQIPQSAYHSPPPSQCPSPFSSPQHQ 310
           ++  QG + H   R  P          S     +Q + Q +  S P    P    SP  Q
Sbjct: 388 EALAQGGM-HIRAR-FPPTTAVSAIPSSSIPLGRQPMAQVSQSSLPMLSSP----SPGQQ 441

Query: 311 VQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHSVAYLPYTASSLSKGSMKKIEITV 370
           VQ  Q     MPP P  +P    Q G PS Q   + S    P  +S L   S        
Sbjct: 442 VQTPQ----SMPPPPQPSP----QPGQPSSQPNSNVSSGPAPSPSSFLPSPS-------P 486

Query: 371 EPSQRPGTAINRSPSPIS-NQPSPWNQHSLYTATTPPSSSPSRGISSQ 417
           +PSQ P TA  R+P   S   P P N          PSS  S   SSQ
Sbjct: 487 QPSQSPVTA--RTPQNFSVPSPGPLN------TPVNPSSVMSPAGSSQ 526



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 72/315 (22%), Positives = 105/315 (33%), Gaps = 54/315 (17%)

Query: 110 QHAAGKQLICLVQEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMN- 168
           Q    +Q     Q P   P +    P  +     +  +   T   QPP QP       N 
Sbjct: 255 QQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQ 314

Query: 169 -----------PSAMQGPSPP------PPPPSYMHIPR-YSTNPITVTVSQNLPSGQTVP 210
                      P   Q  + P       PP  ++  P      P+   V Q   + QT  
Sbjct: 315 PSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQ 374

Query: 211 RALQILPQIPSNLYG-SPGSIYIRQTSQSSSGRQTPQSTPWQSSPQG--PVPHYSQRPLP 267
            A  + P +       + G ++IR     ++      + P  S P G  P+   SQ  LP
Sbjct: 375 AAQMVAPGVQMITEALAQGGMHIRARFPPTT---AVSAIPSSSIPLGRQPMAQVSQSSLP 431

Query: 268 VY----PHQQNYQPSQYSPKQQQIPQSAYHSPPPSQ------CPSPFS-SPQHQVQPSQL 316
           +     P QQ   P    P  Q  PQ    S  P+        PSP S  P    QPSQ 
Sbjct: 432 MLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQS 491

Query: 317 -------GHIFMP-PSPSTTPPHPYQQGPPSYQKQGSHSVAYLPYTASSLSKGSMKKIEI 368
                   +  +P P P  TP +P     P+   Q      YL           +K++  
Sbjct: 492 PVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQ-QYL---------DKLKQLSK 541

Query: 369 TVEPSQRPGTAINRS 383
            +EP +R    I+++
Sbjct: 542 YIEPLRRMINKIDKN 556


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 63.2 bits (152), Expect = 8e-10
 Identities = 84/344 (24%), Positives = 122/344 (35%), Gaps = 74/344 (21%)

Query: 124 PHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPPPPPS 183
           P   P+  A  P  +P      N+  A P +  P         ++P     P PPP P  
Sbjct: 210 PGPTPSATAVPPQGSPTASQAPNQPQA-PTAPVPHTHIQQAPALHPQRPPSPHPPPHPS- 267

Query: 184 YMHIPRYSTNPITVTVSQ-NLPS---------GQTVPRALQILPQI----PSNLYGSPGS 229
               P     P+T +  Q + PS         G   P +LQ  P +    P   +G P  
Sbjct: 268 ----PHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLP-- 321

Query: 230 IYIRQTSQSSSGRQTPQSTPWQSSPQGPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQIPQ 289
                  Q+S G+      P  +SP    PH S +     P  Q+   SQ  P++Q +P 
Sbjct: 322 ------PQASQGQ-----APLGTSPAAAYPHTSLQ----LPASQSALQSQQPPREQPLPP 366

Query: 290 SAY---HSPPPSQCPSP-FSSPQHQVQPSQLGHIFMPPSP----STTPPHPYQQGPPSYQ 341
           +     H  PP   P P   +PQ    P  L      PSP    +  PP      PP+ +
Sbjct: 367 APLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSG----PSPFSMNANLPP------PPALK 416

Query: 342 KQGSHSVAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQPSPWNQHSLYT 401
              S S  + P       +   +   +   P+Q PG   +++  P               
Sbjct: 417 PLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPP--------------- 461

Query: 402 ATTPPSSSPSRGISS-QPKPPFSVNPVYITYTQPTGPSCTPSPS 444
              PP+S P  G+    P+PPF+ +P       P  P   PS S
Sbjct: 462 ---PPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTS 502



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 69/268 (25%), Positives = 95/268 (35%), Gaps = 66/268 (24%)

Query: 152 PPSQPPQQPSSMQTGMNPSAMQGPSPPP-------PPPSYMHIPRYSTNPITVTVSQNLP 204
           PP + P  P+       P AM    PPP       P P     P + + P   +++ NLP
Sbjct: 358 PPREQPLPPA-------PLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLP 410

Query: 205 SGQTVPRALQILPQIPSNLYGSPGSIYIRQTSQSSSGRQTPQSTPWQSSPQGPVPHYSQR 264
                P AL+ L  +         S +   ++     +  PQS P  SSP  P       
Sbjct: 411 P----PPALKPLSSL---------STHHPPSAHPPPLQLMPQSQPLPSSPAQP------- 450

Query: 265 PLPVYPHQQNYQPSQYSPKQQQIPQSAYHSPPPSQCPSPFSSPQHQV--QPSQLGHIFMP 322
             P     QN  P                 PP S  P+      HQV  QP    H F+P
Sbjct: 451 --PGLTQSQNLPP-----------------PPASHPPTGL----HQVAPQPPFAQHPFVP 487

Query: 323 --PSPSTTPPHPYQQGPPSYQKQGSHSVAYLPYTASSLSKGSMKKIEITVEPS-QRPGTA 379
             P P T P  P    PP+    G  + A  P + ++ S GS+        P+ Q    A
Sbjct: 488 GGPPPITPPTCPSTSTPPA----GPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEA 543

Query: 380 INRSPSPISNQPSPWNQHSLYTATTPPS 407
           ++ +  P S  P P +     T    PS
Sbjct: 544 LDDAEEPESPPPPPRSPSPEPTVVDTPS 571


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 63.2 bits (152), Expect = 8e-10
 Identities = 84/344 (24%), Positives = 122/344 (35%), Gaps = 74/344 (21%)

Query: 124  PHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPPPPPS 183
            P   P+  A  P  +P      N+  A P +  P         ++P     P PPP P  
Sbjct: 764  PGPTPSATAVPPQGSPTASQAPNQPQA-PTAPVPHTHIQQAPALHPQRPPSPHPPPHPS- 821

Query: 184  YMHIPRYSTNPITVTVSQ-NLPS---------GQTVPRALQILPQI----PSNLYGSPGS 229
                P     P+T +  Q + PS         G   P +LQ  P +    P   +G P  
Sbjct: 822  ----PHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLP-- 875

Query: 230  IYIRQTSQSSSGRQTPQSTPWQSSPQGPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQIPQ 289
                   Q+S G+      P  +SP    PH S +     P  Q+   SQ  P++Q +P 
Sbjct: 876  ------PQASQGQ-----APLGTSPAAAYPHTSLQ----LPASQSALQSQQPPREQPLPP 920

Query: 290  SAY---HSPPPSQCPSP-FSSPQHQVQPSQLGHIFMPPSP----STTPPHPYQQGPPSYQ 341
            +     H  PP   P P   +PQ    P  L      PSP    +  PP      PP+ +
Sbjct: 921  APLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSG----PSPFSMNANLPP------PPALK 970

Query: 342  KQGSHSVAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQPSPWNQHSLYT 401
               S S  + P       +   +   +   P+Q PG   +++  P               
Sbjct: 971  PLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPP--------------- 1015

Query: 402  ATTPPSSSPSRGISS-QPKPPFSVNPVYITYTQPTGPSCTPSPS 444
               PP+S P  G+    P+PPF+ +P       P  P   PS S
Sbjct: 1016 ---PPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTS 1056



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 69/268 (25%), Positives = 95/268 (35%), Gaps = 66/268 (24%)

Query: 152  PPSQPPQQPSSMQTGMNPSAMQGPSPPP-------PPPSYMHIPRYSTNPITVTVSQNLP 204
            PP + P  P+       P AM    PPP       P P     P + + P   +++ NLP
Sbjct: 912  PPREQPLPPA-------PLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLP 964

Query: 205  SGQTVPRALQILPQIPSNLYGSPGSIYIRQTSQSSSGRQTPQSTPWQSSPQGPVPHYSQR 264
                 P AL+ L  +         S +   ++     +  PQS P  SSP  P       
Sbjct: 965  P----PPALKPLSSL---------STHHPPSAHPPPLQLMPQSQPLPSSPAQP------- 1004

Query: 265  PLPVYPHQQNYQPSQYSPKQQQIPQSAYHSPPPSQCPSPFSSPQHQV--QPSQLGHIFMP 322
              P     QN  P                 PP S  P+      HQV  QP    H F+P
Sbjct: 1005 --PGLTQSQNLPP-----------------PPASHPPTGL----HQVAPQPPFAQHPFVP 1041

Query: 323  --PSPSTTPPHPYQQGPPSYQKQGSHSVAYLPYTASSLSKGSMKKIEITVEPS-QRPGTA 379
              P P T P  P    PP+    G  + A  P + ++ S GS+        P+ Q    A
Sbjct: 1042 GGPPPITPPTCPSTSTPPA----GPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEA 1097

Query: 380  INRSPSPISNQPSPWNQHSLYTATTPPS 407
            ++ +  P S  P P +     T    PS
Sbjct: 1098 LDDAEEPESPPPPPRSPSPEPTVVDTPS 1125


>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 63.2 bits (152), Expect = 8e-10
 Identities = 84/344 (24%), Positives = 122/344 (35%), Gaps = 74/344 (21%)

Query: 124  PHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPPPPPS 183
            P   P+  A  P  +P      N+  A P +  P         ++P     P PPP P  
Sbjct: 764  PGPTPSATAVPPQGSPTASQAPNQPQA-PTAPVPHTHIQQAPALHPQRPPSPHPPPHPS- 821

Query: 184  YMHIPRYSTNPITVTVSQ-NLPS---------GQTVPRALQILPQI----PSNLYGSPGS 229
                P     P+T +  Q + PS         G   P +LQ  P +    P   +G P  
Sbjct: 822  ----PHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLP-- 875

Query: 230  IYIRQTSQSSSGRQTPQSTPWQSSPQGPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQIPQ 289
                   Q+S G+      P  +SP    PH S +     P  Q+   SQ  P++Q +P 
Sbjct: 876  ------PQASQGQ-----APLGTSPAAAYPHTSLQ----LPASQSALQSQQPPREQPLPP 920

Query: 290  SAY---HSPPPSQCPSP-FSSPQHQVQPSQLGHIFMPPSP----STTPPHPYQQGPPSYQ 341
            +     H  PP   P P   +PQ    P  L      PSP    +  PP      PP+ +
Sbjct: 921  APLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSG----PSPFSMNANLPP------PPALK 970

Query: 342  KQGSHSVAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQPSPWNQHSLYT 401
               S S  + P       +   +   +   P+Q PG   +++  P               
Sbjct: 971  PLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPP--------------- 1015

Query: 402  ATTPPSSSPSRGISS-QPKPPFSVNPVYITYTQPTGPSCTPSPS 444
               PP+S P  G+    P+PPF+ +P       P  P   PS S
Sbjct: 1016 ---PPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTS 1056



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 69/268 (25%), Positives = 95/268 (35%), Gaps = 66/268 (24%)

Query: 152  PPSQPPQQPSSMQTGMNPSAMQGPSPPP-------PPPSYMHIPRYSTNPITVTVSQNLP 204
            PP + P  P+       P AM    PPP       P P     P + + P   +++ NLP
Sbjct: 912  PPREQPLPPA-------PLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLP 964

Query: 205  SGQTVPRALQILPQIPSNLYGSPGSIYIRQTSQSSSGRQTPQSTPWQSSPQGPVPHYSQR 264
                 P AL+ L  +         S +   ++     +  PQS P  SSP  P       
Sbjct: 965  P----PPALKPLSSL---------STHHPPSAHPPPLQLMPQSQPLPSSPAQP------- 1004

Query: 265  PLPVYPHQQNYQPSQYSPKQQQIPQSAYHSPPPSQCPSPFSSPQHQV--QPSQLGHIFMP 322
              P     QN  P                 PP S  P+      HQV  QP    H F+P
Sbjct: 1005 --PGLTQSQNLPP-----------------PPASHPPTGL----HQVAPQPPFAQHPFVP 1041

Query: 323  --PSPSTTPPHPYQQGPPSYQKQGSHSVAYLPYTASSLSKGSMKKIEITVEPS-QRPGTA 379
              P P T P  P    PP+    G  + A  P + ++ S GS+        P+ Q    A
Sbjct: 1042 GGPPPITPPTCPSTSTPPA----GPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEA 1097

Query: 380  INRSPSPISNQPSPWNQHSLYTATTPPS 407
            ++ +  P S  P P +     T    PS
Sbjct: 1098 LDDAEEPESPPPPPRSPSPEPTVVDTPS 1125


>gi|91199543 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo
            sapiens]
          Length = 1858

 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 111/468 (23%), Positives = 160/468 (34%), Gaps = 89/468 (19%)

Query: 28   VSQCMLQNNNNLEACCRALSQESSKYLYMEYHSPDDNRMNRNRLLHINLGIHSPSSYHPG 87
            + Q  L NNN          Q  SK    + H  + +     +L  +   +H P S H  
Sbjct: 1399 LQQKQLSNNN----------QALSKNHPPQTHVRNSSEQLSQKLPSVPTKLHCPPSPHLE 1448

Query: 88   DGAQLNGGRTLVHSSSDGHIDPQHAAGKQLICLVQEPHSAPAVVAATPNYNP---FFMNE 144
            +  + +   T V     G++ P+  +  Q +     PH + +    TP   P   F+   
Sbjct: 1449 NPPKSSTPHTPVQH---GYLSPKPPS--QQLGSPYRPHHSQSPQVGTPQREPQRNFYPAA 1503

Query: 145  QNRSAATPPSQ--------PPQQPSSMQTGMNPSAMQGPSPPPPPP-----SYMHIPRYS 191
            QN  A T  +         P  Q S+  +  N  ++   +PPPPPP     SY    + S
Sbjct: 1504 QNLPANTQQATSGTLFTQTPSGQSSATYSQFNQQSLNSTAPPPPPPPPPSSSYYQNQQPS 1563

Query: 192  TNPITVTVSQNLPSGQTV--PRALQILP-----QIPSNLYGSPGSIYIRQTSQSSSGRQT 244
             N       +   S QTV      Q LP     Q     + +PG     Q          
Sbjct: 1564 ANFQNYNQLKGSLSQQTVFTSGPNQALPGTTSQQTVPGHHVTPGHFLPSQNPTIHHQTAA 1623

Query: 245  PQSTPWQSSPQGPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQIPQSAYHS-------PPP 297
                P    P  P PH  Q+P     HQQ+       P     P S  HS       PPP
Sbjct: 1624 AVVPPPPPPPPAPGPHLVQQP---NSHQQHSVAHVVGPVHAVTPGSHIHSQTAGHHLPPP 1680

Query: 298  SQCPSPFSSPQHQVQP----------SQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
               P P  +P H   P          +Q  H+      ++ PP P    P S    G H+
Sbjct: 1681 PPPPGP--APHHHPPPHPSTGLQGLQAQHQHVV-----NSAPPPPPPPPPSSVLASGHHT 1733

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQPSPWNQHSLYTATTPPS 407
                  +A +L             P Q P    + +   +   PS    H+  T    P 
Sbjct: 1734 T-----SAQALHH----------PPHQGPPLFPSSAHPTVPPYPSQATHHT--TLGPGPQ 1776

Query: 408  SSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPR-VIPNPTTV 454
              PS    + P  P    PV   + QP GP+  P+P+     P+P +V
Sbjct: 1777 HQPS---GTGPHCPL---PVTGPHLQPQGPNSIPTPTASGFCPHPGSV 1818


>gi|33636768 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo
            sapiens]
          Length = 1858

 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 111/468 (23%), Positives = 160/468 (34%), Gaps = 89/468 (19%)

Query: 28   VSQCMLQNNNNLEACCRALSQESSKYLYMEYHSPDDNRMNRNRLLHINLGIHSPSSYHPG 87
            + Q  L NNN          Q  SK    + H  + +     +L  +   +H P S H  
Sbjct: 1399 LQQKQLSNNN----------QALSKNHPPQTHVRNSSEQLSQKLPSVPTKLHCPPSPHLE 1448

Query: 88   DGAQLNGGRTLVHSSSDGHIDPQHAAGKQLICLVQEPHSAPAVVAATPNYNP---FFMNE 144
            +  + +   T V     G++ P+  +  Q +     PH + +    TP   P   F+   
Sbjct: 1449 NPPKSSTPHTPVQH---GYLSPKPPS--QQLGSPYRPHHSQSPQVGTPQREPQRNFYPAA 1503

Query: 145  QNRSAATPPSQ--------PPQQPSSMQTGMNPSAMQGPSPPPPPP-----SYMHIPRYS 191
            QN  A T  +         P  Q S+  +  N  ++   +PPPPPP     SY    + S
Sbjct: 1504 QNLPANTQQATSGTLFTQTPSGQSSATYSQFNQQSLNSTAPPPPPPPPPSSSYYQNQQPS 1563

Query: 192  TNPITVTVSQNLPSGQTV--PRALQILP-----QIPSNLYGSPGSIYIRQTSQSSSGRQT 244
             N       +   S QTV      Q LP     Q     + +PG     Q          
Sbjct: 1564 ANFQNYNQLKGSLSQQTVFTSGPNQALPGTTSQQTVPGHHVTPGHFLPSQNPTIHHQTAA 1623

Query: 245  PQSTPWQSSPQGPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQIPQSAYHS-------PPP 297
                P    P  P PH  Q+P     HQQ+       P     P S  HS       PPP
Sbjct: 1624 AVVPPPPPPPPAPGPHLVQQP---NSHQQHSVAHVVGPVHAVTPGSHIHSQTAGHHLPPP 1680

Query: 298  SQCPSPFSSPQHQVQP----------SQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHS 347
               P P  +P H   P          +Q  H+      ++ PP P    P S    G H+
Sbjct: 1681 PPPPGP--APHHHPPPHPSTGLQGLQAQHQHVV-----NSAPPPPPPPPPSSVLASGHHT 1733

Query: 348  VAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQPSPWNQHSLYTATTPPS 407
                  +A +L             P Q P    + +   +   PS    H+  T    P 
Sbjct: 1734 T-----SAQALHH----------PPHQGPPLFPSSAHPTVPPYPSQATHHT--TLGPGPQ 1776

Query: 408  SSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPR-VIPNPTTV 454
              PS    + P  P    PV   + QP GP+  P+P+     P+P +V
Sbjct: 1777 HQPS---GTGPHCPL---PVTGPHLQPQGPNSIPTPTASGFCPHPGSV 1818


>gi|34365793 WNK lysine deficient protein kinase 4 [Homo sapiens]
          Length = 1243

 Score = 60.8 bits (146), Expect = 4e-09
 Identities = 115/479 (24%), Positives = 168/479 (35%), Gaps = 103/479 (21%)

Query: 235  TSQSSSGRQTPQSTPWQ-SSPQGPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQIPQSAYH 293
            TS SS G       P+   +P  P P +     P +P      PS +SP   Q+  S+  
Sbjct: 802  TSSSSPGTPLSPGNPFSPGTPISPGPIFPITSPPCHP-----SPSPFSPISSQV--SSNP 854

Query: 294  SPPPSQCPSPFSS--PQHQVQPSQLGHIFMP-PSPSTTPP--------HPYQQGPPSYQK 342
            SP P+  P PFSS  P+  V  SQ     +P  SP T  P         P+    PS   
Sbjct: 855  SPHPTSSPLPFSSSTPEFPVPLSQCPWSSLPTTSPPTFSPTCSQVTLSSPFFPPCPSTSS 914

Query: 343  QGSHSVAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQPS--------PW 394
              S + A L   AS+ S   M   +  + PS  PG      P+P S  PS        P 
Sbjct: 915  FPSTTAAPLLSLASAFSLAVMTVAQSLLSPS--PGLLSQSPPAPPSPLPSLPLPPPVAPG 972

Query: 395  NQHS-------LYTATTPPSSSPSRG------ISSQPKPPF--------SVNPVYITYTQ 433
             Q S       + +  +PP + P  G      IS + KP          S  P      Q
Sbjct: 973  GQESPSPHTAEVESEASPPPARPLPGEARLAPISEEGKPQLVGRFQVTSSKEPAEPLPLQ 1032

Query: 434  PTGPSCTPSPSPRVIP--------------NPTTVFKITVGRATTENLLNLVDQE----- 474
            PT P+ + SP P                   P T   +       E L   V++E     
Sbjct: 1033 PTSPTLSGSPKPSTPQLTSESSDTEDSAGGGPETREALAESDRAAEGLGAGVEEEGDDGK 1092

Query: 475  --ERSAAPEPI-QPISVIPGSGGEKGSHKYQRSSSSGSDDYAYTQALLLHQRARMERLAK 531
              +   +P+P+  P  V             + S SSG D+  + +   L Q+  +  +  
Sbjct: 1093 EPQVGGSPQPLSHPSPVWMNYSYSSLCLSSEESESSGEDEEFWAELQSLRQK-HLSEVET 1151

Query: 532  QLKLEKEELERLKSEVNGMEHDLMQRRLRRVSCTTAIPTPEEMTRLRSMNRQLQINVDCT 591
               L+K+E+E L S +                    I  P  M  L S  R+L       
Sbjct: 1152 LQTLQKKEIEDLYSRLGKQP-------------PPGIVAPAAM--LSSRQRRL------- 1189

Query: 592  LKEVDLLQSRGNFDPKAMNNFYDNIEPGPVVPPKPSKKDSSDPCTIERKARRISVTSKV 650
                    S+G+F     N+   +  PGP +  + S   SS     +R ++ ++    V
Sbjct: 1190 --------SKGSFPTSRRNSLQRSEPPGPGIMRRNSLSGSSTGSQEQRASKGVTFAGDV 1240



 Score = 34.3 bits (77), Expect = 0.41
 Identities = 70/304 (23%), Positives = 100/304 (32%), Gaps = 55/304 (18%)

Query: 153  PSQPPQQPSSMQTGMNPSAMQGPSPPP--------PPP----SYMHIPRYSTNPITVTVS 200
            PS  P  P S Q   NPS     SP P        P P     +  +P  S    + T S
Sbjct: 838  PSPSPFSPISSQVSSNPSPHPTSSPLPFSSSTPEFPVPLSQCPWSSLPTTSPPTFSPTCS 897

Query: 201  Q---------NLPSGQTVPRALQILPQIPSNLYGSPGSIYIRQTSQSSSGRQTPQSTPWQ 251
            Q           PS  + P +    P +      S   + + Q+  S S     QS P  
Sbjct: 898  QVTLSSPFFPPCPSTSSFP-STTAAPLLSLASAFSLAVMTVAQSLLSPSPGLLSQSPPAP 956

Query: 252  SSPQGPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQIPQSAYHSPPPSQCPSP----FSSP 307
             SP   +P     P PV P        Q SP        +  SPPP++ P P     +  
Sbjct: 957  PSPLPSLP----LPPPVAP------GGQESPSPHTAEVESEASPPPAR-PLPGEARLAPI 1005

Query: 308  QHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHSVAYL--------------PY 353
              + +P  +G   +  S     P P Q   P+       S   L              P 
Sbjct: 1006 SEEGKPQLVGRFQVTSSKEPAEPLPLQPTSPTLSGSPKPSTPQLTSESSDTEDSAGGGPE 1065

Query: 354  TASSLSKG--SMKKIEITVEPSQRPG--TAINRSPSPISNQPSPWNQHSLYTATTPPSSS 409
            T  +L++   + + +   VE     G    +  SP P+S+    W  +S  +       S
Sbjct: 1066 TREALAESDRAAEGLGAGVEEEGDDGKEPQVGGSPQPLSHPSPVWMNYSYSSLCLSSEES 1125

Query: 410  PSRG 413
             S G
Sbjct: 1126 ESSG 1129



 Score = 30.4 bits (67), Expect = 5.9
 Identities = 31/120 (25%), Positives = 46/120 (38%), Gaps = 5/120 (4%)

Query: 349 AYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQPSPWNQHSLYTATTPPSS 408
           A LP     L   S ++++ +     R  TA + S S      SP N  S  T  +P   
Sbjct: 769 APLPALPVPLPDPSNEELQSSTSLEHRSWTAFSTSSSSPGTPLSPGNPFSPGTPISPGPI 828

Query: 409 SPSRGISSQPKP-PFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTTVFKITVGRATTENL 467
            P       P P PFS     I+    + PS  P+ SP    + T  F + + +    +L
Sbjct: 829 FPITSPPCHPSPSPFSP----ISSQVSSNPSPHPTSSPLPFSSSTPEFPVPLSQCPWSSL 884


>gi|222352122 hypothetical protein LOC284297 [Homo sapiens]
          Length = 1573

 Score = 60.5 bits (145), Expect = 5e-09
 Identities = 98/402 (24%), Positives = 141/402 (35%), Gaps = 72/402 (17%)

Query: 126  SAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPPPPPSYM 185
            +A      TP+  P         A T  S     P S  T    S     SPP P P+  
Sbjct: 998  AATRTAPPTPSPGPSASPGPPGPALTSDSSRELTPHSALTSEATSDAPDTSPPTPDPASR 1057

Query: 186  HIPRYSTNPITVTVSQNL----PSGQTVPRALQI-----LPQIPSNLYGSPGSIYIRQTS 236
                  TNP  +  S +     P    VP          LP +P  L   P S     TS
Sbjct: 1058 ------TNPDLILTSPDFALSTPDSSVVPALTPEPSPTPLPTLPKELTSDP-STPSEVTS 1110

Query: 237  QSSSGRQTPQS--------TPWQS-------SPQ-GPVPHYSQRPLPVY---------PH 271
             S +  Q P+S        TP+ S       SP   P PH +  P P           P 
Sbjct: 1111 LSPTSEQVPESDTTPDLDTTPYSSTVSEYSRSPDPSPSPHPTTTPDPTMAPDPITTLNPT 1170

Query: 272  QQNYQPSQYSPKQQQIPQSAYHS---PPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTT 328
               + P+   P     P +  HS   P P+  P PF++  H           M P P+TT
Sbjct: 1171 VTPHFPTTPHPTTTPHPTTITHSTMIPDPTTTPQPFTTITHST---------MIPDPTTT 1221

Query: 329  PPHPYQQGPPSYQKQGSHSVAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPIS 388
            P  P+    P+      HS    P+  ++    ++    +  +P+  P       P+ + 
Sbjct: 1222 P-QPFTTMQPTTTP---HSTT--PHPTTTPHPTTITHSTMIPDPTTTPQPFTTMQPTTM- 1274

Query: 389  NQPSPWNQHSLYTATTPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVI 448
              P P       T T  P+++P    ++ P P  + +P  +T    T P  T +P P   
Sbjct: 1275 --PHP-------TTTPHPTTTPHP--TTTPHPTTTPHPT-MTPDPTTTPYPTTTPDPTTT 1322

Query: 449  PNPTTVFKITVGRATTENLLNLVDQEERSAAPEPIQPISVIP 490
            P+PTT    +    TT +L   +  E  S    P    S+ P
Sbjct: 1323 PHPTTPDPSSTPVITTVSLPTSLGTELSSPTLAPTVKPSLHP 1364



 Score = 57.0 bits (136), Expect = 6e-08
 Identities = 72/327 (22%), Positives = 116/327 (35%), Gaps = 51/327 (15%)

Query: 153  PSQPPQQPSSMQTGMNPSAMQGPSPPPPPPSYMHIPRYSTNPITVTVSQNLPSGQTVPRA 212
            P + P +P++ +T   P+   GPS  P PP     P  +++        +  + +    A
Sbjct: 990  PERRPPRPAATRTAP-PTPSPGPSASPGPPG----PALTSDSSRELTPHSALTSEATSDA 1044

Query: 213  LQILPQIPSNLYGSPGSIYIRQTSQSSSGRQTPQSTPWQSSPQGPVPHYSQRPLPVYPHQ 272
                P  P     +   + +     + S       TP  S      P  S  PLP  P +
Sbjct: 1045 PDTSPPTPDPASRTNPDLILTSPDFALS-------TPDSSVVPALTPEPSPTPLPTLPKE 1097

Query: 273  QNYQPS------QYSPKQQQIPQSAY-----------------HSPPPSQCPSPFSSPQH 309
                PS        SP  +Q+P+S                    SP PS  P P ++P  
Sbjct: 1098 LTSDPSTPSEVTSLSPTSEQVPESDTTPDLDTTPYSSTVSEYSRSPDPSPSPHPTTTPDP 1157

Query: 310  QVQPSQLGHIFMPPSPS-TTPPHPYQQGPPSYQKQGSHSVAYLPYTASSLSKGSMKKIEI 368
             + P  +  +    +P   T PHP     P+     +HS      T +     ++    +
Sbjct: 1158 TMAPDPITTLNPTVTPHFPTTPHPTTTPHPTTI---THSTMIPDPTTTPQPFTTITHSTM 1214

Query: 369  TVEPSQ--RPGTAINRSPSPISNQPSPWNQHSLYTATTPPSSSPSRGISSQPKPPFSVNP 426
              +P+   +P T +  + +P S  P P         TT P  +     +  P P  +  P
Sbjct: 1215 IPDPTTTPQPFTTMQPTTTPHSTTPHP---------TTTPHPTTITHSTMIPDPTTTPQP 1265

Query: 427  VYITYTQPTGPSCTPSPSPRVIPNPTT 453
             + T    T P  T +P P   P+PTT
Sbjct: 1266 -FTTMQPTTMPHPTTTPHPTTTPHPTT 1291



 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 85/395 (21%), Positives = 125/395 (31%), Gaps = 74/395 (18%)

Query: 142  MNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPPPPPSYMHIPRYSTNPITVTVSQ 201
            ++E +RS    PS  P          +P     P+  P  P+  H P  + +P T+T S 
Sbjct: 1136 VSEYSRSPDPSPSPHPTTTPDPTMAPDPITTLNPTVTPHFPTTPH-PTTTPHPTTITHST 1194

Query: 202  NLPSGQTVPRALQILPQIPSNLYGSPGSIYIRQTSQSSSGRQTPQSTPWQSSPQGPVPHY 261
             +P   T P+    +            S  I   + +     T Q T   ++P    PH 
Sbjct: 1195 MIPDPTTTPQPFTTITH----------STMIPDPTTTPQPFTTMQPT---TTPHSTTPHP 1241

Query: 262  SQRPLPVYPHQQNYQPSQYSPKQQQIPQSAYHSPPPSQCPSPFSSPQHQV--QPSQLGHI 319
            +  P P         P   +  Q          P P+  P P ++P       P+   H 
Sbjct: 1242 TTTPHPTTITHSTMIPDPTTTPQPFTTMQPTTMPHPTTTPHPTTTPHPTTTPHPTTTPHP 1301

Query: 320  FMPPSPSTTP-----------PHPYQQGPPSYQ------------------------KQG 344
             M P P+TTP           PHP    P S                          K  
Sbjct: 1302 TMTPDPTTTPYPTTTPDPTTTPHPTTPDPSSTPVITTVSLPTSLGTELSSPTLAPTVKPS 1361

Query: 345  SHS----VAYLPYTASSL-----------SKGSMKKIEITVEPSQRPGTAINRSPSPISN 389
             H      A  P+T++S            S  S      +++P         RS SP   
Sbjct: 1362 LHPQLTFTAPAPHTSTSQIPTLEPSPALESSPSRSSTATSMDPLSTEDFKPPRSQSPNLT 1421

Query: 390  QPSPWNQHSLYTATTPPS---SSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPR 446
             P     HS    T  P    S  +  +   P  P ++ P       P GP   P+P  R
Sbjct: 1422 PPPTHTPHSASDLTVSPDPLLSPTAHPLDHPPLDPLTLGPTPGQSPGPHGPCVAPTPPVR 1481

Query: 447  VI--PNPTTVFKITVGR---ATTENLLNLVDQEER 476
            V+    P  V  +   R      + L  +V+QE +
Sbjct: 1482 VMACEPPALVELVAAVRDVGGQLQRLTQVVEQERQ 1516



 Score = 43.1 bits (100), Expect = 9e-04
 Identities = 58/252 (23%), Positives = 83/252 (32%), Gaps = 26/252 (10%)

Query: 123  EPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQ-----QPSSM---QTGMNPSAMQG 174
            +P + P      P   P      + +    P+  PQ     QP++M    T  +P+    
Sbjct: 1229 QPTTTPHSTTPHPTTTPHPTTITHSTMIPDPTTTPQPFTTMQPTTMPHPTTTPHPTTTPH 1288

Query: 175  PSPPPPPPSYMHIPRYSTNPITVTVSQNLPSGQTVPRALQILPQIPS--NLYGSPGSIYI 232
            P+  P P +  H P  + +P T       P   T P      P           P S+  
Sbjct: 1289 PTTTPHPTTTPH-PTMTPDPTTTPYPTTTPDPTTTPHPTTPDPSSTPVITTVSLPTSLGT 1347

Query: 233  RQTSQSSSGRQTPQSTPWQSSPQGPVPHYSQRPLPVYPHQQNYQ--PSQYSPKQQQIPQS 290
              +S + +    P   P Q +   P PH S   +P        +  PS+ S      P S
Sbjct: 1348 ELSSPTLAPTVKPSLHP-QLTFTAPAPHTSTSQIPTLEPSPALESSPSRSSTATSMDPLS 1406

Query: 291  AY-HSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTP-PHPYQQ--------GPPSY 340
                 PP SQ P+    P H   P     + + P P  +P  HP           GP   
Sbjct: 1407 TEDFKPPRSQSPNLTPPPTH--TPHSASDLTVSPDPLLSPTAHPLDHPPLDPLTLGPTPG 1464

Query: 341  QKQGSHSVAYLP 352
            Q  G H     P
Sbjct: 1465 QSPGPHGPCVAP 1476


>gi|31543543 retinoic acid induced 17 [Homo sapiens]
          Length = 1067

 Score = 60.1 bits (144), Expect = 7e-09
 Identities = 84/293 (28%), Positives = 107/293 (36%), Gaps = 79/293 (26%)

Query: 134 TPNYNPFFMNEQN-RSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPPPPPSYMHIPRYST 192
           T  YN  FMN+   R  A+        P+SM  GM PS M GP                 
Sbjct: 323 TQAYNSQFMNQPGPRGPASMGGS--MNPASMAAGMTPSGMSGP----------------- 363

Query: 193 NPITVTVSQNLPSGQTVPRALQILPQIPSNLYGSPGSIYIRQTSQSSSGRQTPQSTPWQS 252
                      P G   PR   I P      +G+ G    R   Q+  G + PQS P Q+
Sbjct: 364 -----------PMGMNQPRPPGISP------FGTHGQ---RMPQQTYPGPR-PQSLPIQN 402

Query: 253 SPQGPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQIPQ-SAYHSPPPSQCPSPFSSPQH-- 309
                     +RP   YP + NY   QY P  Q   Q   Y +P P   P P +SP +  
Sbjct: 403 I---------KRP---YPGEPNYGNQQYGPNSQFPTQPGQYPAPNP---PRPLTSPNYPG 447

Query: 310 QVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHSVAYLPYTASSLSKGSMKKIEIT 369
           Q  PSQ       PS    PP     G   Y K    +     ++ SS S  S    +  
Sbjct: 448 QRMPSQ-------PSSGQYPPPTVNMG--QYYKPEQFNGQNNTFSGSSYSNYS----QGN 494

Query: 370 VEPSQRPGTAINRSPSPISNQPSPWNQHSLYTATTPPSSSPSRGISSQPKPPF 422
           V    RP    N   SP+   P+P        ++ PP  SPS+ +    KPPF
Sbjct: 495 VNRPPRPVPVANYPHSPVPGNPTP---PMTPGSSIPPYLSPSQDV----KPPF 540



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 72/324 (22%), Positives = 117/324 (36%), Gaps = 52/324 (16%)

Query: 143 NEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPPPPPSYMHIPRYSTNPITVTVSQN 202
           ++++R +  P   P Q P S  + M P+        P          Y + P     +Q 
Sbjct: 111 HQKSRQSDPPGKLPMQPPLSSMSSMKPTLSHSDGSFP----------YDSVPWQQNTNQP 160

Query: 203 LPSGQTVPRALQILPQIPSNLYGSPGSIYIRQTSQSSSGRQTPQSTPWQSSPQGPVPHYS 262
             S   V     +     S + G+P +        +++    P   P  S      P  +
Sbjct: 161 PGSLSVVTTVWGVTNTSQSQVLGNPMA--------NANNPMNPGGNPMASGMTTSNPGLN 212

Query: 263 QRPLPVYPHQQNYQPSQYSPKQQQIPQSAYHSPP-PSQCPSPFSSPQHQVQPSQLGHIFM 321
               P +  QQ    ++  P Q  I QS Y  P  P       S P     P+ +G   +
Sbjct: 213 S---PQFAGQQQQFSAKAGPAQPYIQQSMYGRPNYPGSGGFGASYPGGPNAPAGMG---I 266

Query: 322 PPSPSTTPPHPYQQGPPSYQKQGSHSVAYLPYTASSLSKGSMKKIEITVEPS------QR 375
           PP   T PP  + Q   +     + +VA    TA++ +  ++  ++ T            
Sbjct: 267 PPH--TRPPADFTQPAAA---AAAAAVAAAAATATATATATVAALQETQNKDINQYGPMG 321

Query: 376 PGTAINRSPSPISNQPSPWNQHSLYTATTPPS----------SSPSRGISSQPKPPFSVN 425
           P  A N   S   NQP P    S+  +  P S          S P  G+ +QP+PP  ++
Sbjct: 322 PTQAYN---SQFMNQPGPRGPASMGGSMNPASMAAGMTPSGMSGPPMGM-NQPRPP-GIS 376

Query: 426 PVYITYTQPTGPSCTPSPSPRVIP 449
           P + T+ Q       P P P+ +P
Sbjct: 377 P-FGTHGQRMPQQTYPGPRPQSLP 399



 Score = 32.7 bits (73), Expect = 1.2
 Identities = 52/180 (28%), Positives = 71/180 (39%), Gaps = 28/180 (15%)

Query: 290  SAYHSPPPSQCPSPFSSPQHQVQPSQL-GH---IFMPPSPSTTPPHPYQQGPPSYQKQGS 345
            S Y  PPP   P   +S  +  Q +   GH    F   +P  T  + +  GPP    Q S
Sbjct: 870  SPYPLPPP---PGGTNSNDYSSQGNNYQGHGNFDFPHGNPGGTSMNDFMHGPP----QLS 922

Query: 346  HSVAYLPYTASSLSKGSMKKIEITVE---PSQRPGTAINRS---PSPISNQPSPWNQHSL 399
            H    +P   ++L K     ++ T+     S +P  +I +    P P S+Q  P   HS 
Sbjct: 923  HPPD-MPNNMAALEKPLSHPMQETMPHAGSSDQPHPSIQQGLHVPHP-SSQSGPPLHHS- 979

Query: 400  YTATTPPSSSPSR-----GISSQPKPPFSVNPVYITYTQ--PTGPSCTPSPSPRVIPNPT 452
              A  PP S P R       SS P    + NP      Q    G S  P PS  ++P  T
Sbjct: 980  -GAPPPPPSQPPRQPPQAAPSSHPHSDLTFNPSSALEGQAGAQGASDMPEPSLDLLPELT 1038



 Score = 31.2 bits (69), Expect = 3.5
 Identities = 56/222 (25%), Positives = 72/222 (32%), Gaps = 58/222 (26%)

Query: 156  PPQQPSSMQTGMNPSAM-------------QGPSPPPPPPSYMHIPRYSTNPITVTVSQN 202
            P   PS     M+PS M              GPSP P PP     P   TN    +   N
Sbjct: 837  PDGIPSKRFKTMSPSQMIMPNVMEMIAALGPGPSPYPLPP-----PPGGTNSNDYSSQGN 891

Query: 203  LPSGQTVPRALQILPQIPSNL---YGSPGSIYIRQTSQSSSGRQTPQSTPWQSSPQGPVP 259
               G               N    +G+PG      TS +      PQ +     P     
Sbjct: 892  NYQGH-------------GNFDFPHGNPGG-----TSMNDFMHGPPQLSHPPDMPNNMAA 933

Query: 260  HYSQRPLPVYPHQQNYQPSQYSPKQQQIPQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHI 319
               ++PL  +P Q+    +  S +     Q   H P PS    P   P H        H 
Sbjct: 934  --LEKPLS-HPMQETMPHAGSSDQPHPSIQQGLHVPHPSSQSGP---PLH--------HS 979

Query: 320  FMPPSPSTTPPHPYQQGPPSYQKQGSHSVAYLPYTASSLSKG 361
              PP P + PP    Q  PS     SH  + L +  SS  +G
Sbjct: 980  GAPPPPPSQPPRQPPQAAPS-----SHPHSDLTFNPSSALEG 1016


>gi|54860079 nadrin isoform 1 [Homo sapiens]
          Length = 881

 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 89/341 (26%), Positives = 124/341 (36%), Gaps = 81/341 (23%)

Query: 146 NRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPPPPPSYMHIPRYSTNPITVTVSQNLPS 205
           NR   +P  QPP  P+   T +       P+ P PPP                 +++   
Sbjct: 515 NRKHISPAFQPPLPPTDGSTVV-------PAGPEPPPQSSR-------------AESSSG 554

Query: 206 GQTVPRALQILPQIPSNLYGSPG------SIYI----RQTSQSSSGRQTPQSTPWQS--- 252
           G TVP +  IL Q PS   GSP       S  +    R  SQ +SG+  PQ+        
Sbjct: 555 GGTVPSSAGILEQGPSPGDGSPPKPKDPVSAAVPAPGRNNSQIASGQNQPQAAAGSHQLS 614

Query: 253 -----SPQGPVPHYSQR----PLPVYPHQQNYQPSQYSPKQQQIPQSAYHSP-----PPS 298
                +  GP PH  +R    P P  P   N  P    P  Q    ++ H P     PP+
Sbjct: 615 MGQPHNAAGPSPHTLRRAVKKPAPAPPKPGNPPPGH--PGGQSSSGTSQHPPSLSPKPPT 672

Query: 299 QCPSPFSSPQHQV--QPSQLGHIFMPP------SPSTTPPHPYQQGPPSYQKQGSHSVAY 350
           + PSP +    Q   QPS    +  P       SP   P HP  Q PP+      H+   
Sbjct: 673 RSPSPPTQHTGQPPGQPSAPSQLSAPRRYSSSLSPIQAPNHPPPQ-PPTQATPLMHTKPN 731

Query: 351 LPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQPSPWNQHSLYTATT-----P 405
                + ++  S   +E   +PS  P     ++P+P S  P      SL    T     P
Sbjct: 732 SQGPPNPMALPSEHGLE---QPSHTP----PQTPTPPSTPPLGKQNPSLPAPQTLAGGNP 784

Query: 406 PSSSPSRGISSQPKPPFSVNPVYITYTQPTG-PSCTPSPSP 445
            ++ P  G   +P+P            +P   PS  P P P
Sbjct: 785 ETAQPHAGTLPRPRP----------VPKPRNRPSVPPPPQP 815



 Score = 50.4 bits (119), Expect = 6e-06
 Identities = 67/283 (23%), Positives = 103/283 (36%), Gaps = 55/283 (19%)

Query: 103 SDGHIDPQHAAGKQLICLVQEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQP-- 160
           + G   PQ AAG   + + Q PH+A      +P+     + +   +   P + PP  P  
Sbjct: 598 ASGQNQPQAAAGSHQLSMGQ-PHNA---AGPSPHTLRRAVKKPAPAPPKPGNPPPGHPGG 653

Query: 161 -SSMQTGMNPSAM------QGPSPP----------PPPPSYMHIPRYSTNPITVTVSQNL 203
            SS  T  +P ++      + PSPP          P  PS +  PR  ++ ++   + N 
Sbjct: 654 QSSSGTSQHPPSLSPKPPTRSPSPPTQHTGQPPGQPSAPSQLSAPRRYSSSLSPIQAPNH 713

Query: 204 PSGQTVPRALQILPQIPSNLYGSPGSIYIRQTSQSSSGRQTPQSTPWQSSPQGPVPHYSQ 263
           P  Q   +A  ++   P N  G P  + +     S  G + P  TP    PQ P P    
Sbjct: 714 PPPQPPTQATPLMHTKP-NSQGPPNPMAL----PSEHGLEQPSHTP----PQTPTP---- 760

Query: 264 RPLPVYPHQQNYQPSQYSPKQQQIPQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPP 323
              P  P      PS  +P+           P     P P   P+ + +PS      +PP
Sbjct: 761 ---PSTPPLGKQNPSLPAPQTLAGGNPETAQPHAGTLPRPRPVPKPRNRPS------VPP 811

Query: 324 SPSTTPPHPYQQGPPSYQKQGSHSVAYLPYTASSLSKGSMKKI 366
            P           PP     G  S+     TAS +   S  ++
Sbjct: 812 PPQ----------PPGVHSAGDSSLTNTAPTASKIVTDSNSRV 844


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.127    0.384 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,749,991
Number of Sequences: 37866
Number of extensions: 2333952
Number of successful extensions: 25324
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 216
Number of HSP's successfully gapped in prelim test: 1327
Number of HSP's that attempted gapping in prelim test: 13835
Number of HSP's gapped (non-prelim): 7509
length of query: 712
length of database: 18,247,518
effective HSP length: 109
effective length of query: 603
effective length of database: 14,120,124
effective search space: 8514434772
effective search space used: 8514434772
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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