BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|94536782 tripartite motif-containing 35 isoform 2 [Homo sapiens] (493 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|94536782 tripartite motif-containing 35 isoform 2 [Homo sapiens] 1030 0.0 gi|21630277 tripartite motif-containing 11 [Homo sapiens] 197 1e-50 gi|15208660 tripartite motif protein 21 [Homo sapiens] 183 4e-46 gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens] 181 1e-45 gi|22749269 ring finger protein 129 [Homo sapiens] 178 1e-44 gi|157743261 tripartite motif-containing 75 [Homo sapiens] 178 1e-44 gi|5730009 ret finger protein [Homo sapiens] 177 3e-44 gi|217035095 tripartite motif-containing 62 [Homo sapiens] 176 6e-44 gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens] 174 1e-43 gi|112421127 tripartite motif-containing 58 [Homo sapiens] 172 6e-43 gi|88999601 tripartite motif-containing 69 isoform a [Homo sapiens] 166 3e-41 gi|44680122 tripartite motif-containing 7 isoform 1 [Homo sapiens] 166 6e-41 gi|37622899 ring finger protein 137 [Homo sapiens] 164 1e-40 gi|30023818 tripartite motif protein 50A [Homo sapiens] 159 7e-39 gi|68160933 tripartite motif-containing 17 isoform 1 [Homo sapiens] 153 4e-37 gi|7705825 tripartite motif-containing 17 isoform 1 [Homo sapiens] 153 4e-37 gi|15011941 tripartite motif protein TRIM4 isoform beta [Homo sa... 145 1e-34 gi|157426898 tripartite motif-containing 10 isoform 1 [Homo sapi... 144 1e-34 gi|5454014 tripartite motif-containing 38 [Homo sapiens] 141 2e-33 gi|18079262 tripartite motif-containing 6 isoform 2 [Homo sapiens] 139 4e-33 gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens] 139 4e-33 gi|42516572 tripartite motif-containing 41 isoform 1 [Homo sapiens] 137 2e-32 gi|14670266 tripartite motif protein TRIM4 isoform alpha [Homo s... 135 8e-32 gi|56605981 tripartite motif-containing 72 [Homo sapiens] 135 1e-31 gi|68160935 tripartite motif-containing 17 isoform 2 [Homo sapiens] 134 2e-31 gi|31542779 tripartite motif family-like 1 [Homo sapiens] 131 1e-30 gi|20270353 tripartite motif-containing 43 [Homo sapiens] 129 5e-30 gi|88953346 PREDICTED: Tripartite motif-containing protein 43-li... 129 8e-30 gi|157426896 tripartite motif-containing 10 isoform 2 [Homo sapi... 127 2e-29 gi|117938316 tripartite motif-containing 22 [Homo sapiens] 127 3e-29 >gi|94536782 tripartite motif-containing 35 isoform 2 [Homo sapiens] Length = 493 Score = 1030 bits (2663), Expect = 0.0 Identities = 493/493 (100%), Positives = 493/493 (100%) Query: 1 MERSPDVSPGPSRSFKEELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWEVQVSPTCPVC 60 MERSPDVSPGPSRSFKEELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWEVQVSPTCPVC Sbjct: 1 MERSPDVSPGPSRSFKEELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWEVQVSPTCPVC 60 Query: 61 KDRASPADLRTNHTLNNLVEKLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLC 120 KDRASPADLRTNHTLNNLVEKLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLC Sbjct: 61 KDRASPADLRTNHTLNNLVEKLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLC 120 Query: 121 CSCQADPRHQGHRVQPVKDTAHDFRAKCRNMEHALREKAKAFWAMRRSYEAIAKHNQVEA 180 CSCQADPRHQGHRVQPVKDTAHDFRAKCRNMEHALREKAKAFWAMRRSYEAIAKHNQVEA Sbjct: 121 CSCQADPRHQGHRVQPVKDTAHDFRAKCRNMEHALREKAKAFWAMRRSYEAIAKHNQVEA 180 Query: 181 AWLEGRIRQEFDKLREFLRVEEQAILDAMAEETRQKQLLADEKMKQLTEETEVLAHEIER 240 AWLEGRIRQEFDKLREFLRVEEQAILDAMAEETRQKQLLADEKMKQLTEETEVLAHEIER Sbjct: 181 AWLEGRIRQEFDKLREFLRVEEQAILDAMAEETRQKQLLADEKMKQLTEETEVLAHEIER 240 Query: 241 LQMEMKEDDVSFLMKHKSRKRRLFCTMEPEPVQPGMLIDVCKYLGSLQYRVWKKMLASVE 300 LQMEMKEDDVSFLMKHKSRKRRLFCTMEPEPVQPGMLIDVCKYLGSLQYRVWKKMLASVE Sbjct: 241 LQMEMKEDDVSFLMKHKSRKRRLFCTMEPEPVQPGMLIDVCKYLGSLQYRVWKKMLASVE 300 Query: 301 SVPFSFDPNTAAGWLSVSDDLTSVTNHGYRVQVENPERFSSAPCLLGSRVFSQGSHAWEV 360 SVPFSFDPNTAAGWLSVSDDLTSVTNHGYRVQVENPERFSSAPCLLGSRVFSQGSHAWEV Sbjct: 301 SVPFSFDPNTAAGWLSVSDDLTSVTNHGYRVQVENPERFSSAPCLLGSRVFSQGSHAWEV 360 Query: 361 ALGGLQSWRVGVVRVRQDSGAEGHSHSCYHDTRSGFWYVCRTQGVEGDHCVTSDPATSPL 420 ALGGLQSWRVGVVRVRQDSGAEGHSHSCYHDTRSGFWYVCRTQGVEGDHCVTSDPATSPL Sbjct: 361 ALGGLQSWRVGVVRVRQDSGAEGHSHSCYHDTRSGFWYVCRTQGVEGDHCVTSDPATSPL 420 Query: 421 VLAIPRRLRVELECEEGELSFYDAERHCHLYTFHARFGEVRPYFYLGGARGAGPPEPLRI 480 VLAIPRRLRVELECEEGELSFYDAERHCHLYTFHARFGEVRPYFYLGGARGAGPPEPLRI Sbjct: 421 VLAIPRRLRVELECEEGELSFYDAERHCHLYTFHARFGEVRPYFYLGGARGAGPPEPLRI 480 Query: 481 CPLHISVKEELDG 493 CPLHISVKEELDG Sbjct: 481 CPLHISVKEELDG 493 >gi|21630277 tripartite motif-containing 11 [Homo sapiens] Length = 468 Score = 197 bits (502), Expect = 1e-50 Identities = 149/481 (30%), Positives = 224/481 (46%), Gaps = 35/481 (7%) Query: 8 SPGPSRSFKEELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWEVQVSP-TCPVCKDRASP 66 +P S + +EE CA+C D F D V CGHNFCR C+ RCW P CP C++ + Sbjct: 3 APDLSTNLQEEATCAICLDYFTDPVMTDCGHNFCRECIRRCWGQPEGPYACPECRELSPQ 62 Query: 67 ADLRTNHTLNNLVEKLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQAD 126 +LR N L + E R S VC HR L+ FC ++ LLC +C+ Sbjct: 63 RNLRPNRPLAKMAEMARRLHP-----PSPVPQGVCPAHREPLAAFCGDELRLLCAACERS 117 Query: 127 PRHQGHRVQPVKDTAHDFRAKC-RNMEHALREKAKAFWAMRRSYE-AIAKHNQVEAAWLE 184 H HRV+P++D A D +AK +++EH ++ A ++ E + VE+ Sbjct: 118 GEHWAHRVRPLQDAAEDLKAKLEKSLEHLRKQMQDALLFQAQADETCVLWQKMVESQ--R 175 Query: 185 GRIRQEFDKLREFLRVEEQAILDAMAEETRQKQLLADEKMKQLTEETEVLAHEIERLQME 244 + EF++LR L EEQ +L + EE + E L +++ LA I L+ Sbjct: 176 QNVLGEFERLRRLLAEEEQQLLQRLEEEELEVLPRLREGAAHLGQQSAHLAELIAELEGR 235 Query: 245 MKEDDVSFLMKHKSRKRRL-FCTMEPEPVQPGMLIDVCKYLGSLQYRVWKKMLASVESVP 303 + + L K RR+ ++P V P L VC+ G ++ ++ V Sbjct: 236 CQLPALGLLQDIKDALRRVQDVKLQPPEVVPMELRTVCRVPGLVE--TLRRFRGDV---- 289 Query: 304 FSFDPNTAAGWLSVSDDLTSVTNHGYRVQV-ENPERFSSAPCLLGSRVFSQGSHAWEVAL 362 + DP+TA L +S+D SV R + ++PERF PC+LG F+ G H WEV + Sbjct: 290 -TLDPDTANPELILSEDRRSVQRGDLRQALPDSPERFDPGPCVLGQERFTSGRHYWEVEV 348 Query: 363 GGLQSWRVGVVRVRQDSGAEGHSHSCYHDTRSGFWYVCRTQGVEGDHCVTSDPATSPLVL 422 G SW +GV R + +G +GFW + G + +S+ A +PL Sbjct: 349 GDRTSWALGVCRENVNRKEKGEL-----SAGNGFWILV----FLGSYYNSSERALAPL-R 398 Query: 423 AIPRRLRVELECEEGELSFYDAERHCHLYTFH--ARFGEVRPYFYLGGARGAGPPEPLRI 480 PRR+ + L+ E G LSFY A L+ F G +RP F + + P P+ I Sbjct: 399 DPPRRVGIFLDYEAGHLSFYSATDGSLLFIFPEIPFSGTLRPLF----SPLSSSPTPMTI 454 Query: 481 C 481 C Sbjct: 455 C 455 >gi|15208660 tripartite motif protein 21 [Homo sapiens] Length = 475 Score = 183 bits (464), Expect = 4e-46 Identities = 148/496 (29%), Positives = 236/496 (47%), Gaps = 53/496 (10%) Query: 17 EELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWEVQVSPTCPVCKDRASPADLRTNHTLN 76 EE+ C +C DPF + V++ CGH+FC+ C+S+ + S CPVC+ R +LR N L Sbjct: 12 EEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGS-VCPVCRQRFLLKNLRPNRQLA 70 Query: 77 NLVEKLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQADPRHQGHRVQP 136 N+V L E T C +H +L LFC +D + LC C +H+ H + P Sbjct: 71 NMVNNLKEISQEAREGTQ---GERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAMVP 127 Query: 137 VKDTAHDFRAKCR------NMEHALREKAKAFWAMRRSYEAIAKHNQVEAAWLEGRIRQE 190 +++ A +++ K + + L EK + A++R+ Q + RI E Sbjct: 128 LEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQ------KSRIHAE 181 Query: 191 FDKLREFLRVEEQAILDAMAEETRQKQLLADEKMKQLTEETEVLAHEIERLQ-------M 243 F + + FL EEQ L + ++ R++ + EK +L ++++ L I L + Sbjct: 182 FVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSAL 241 Query: 244 EMKEDDVSFLMKHKSRKRRLFCTMEPEPVQPGMLIDVCKYLGSLQYRVWKKMLASVESVP 303 E+ ++ + L + +S + PE L VC G KKML + +V Sbjct: 242 ELLQEVIIVLERSESWNLKDLDITSPE------LRSVCHVPG------LKKMLRTC-AVH 288 Query: 304 FSFDPNTAAGWLSVSDDLTSVTNHGYRVQVE-NPERFSSAPCLLGSRVFSQGSHAWEVAL 362 + DP+TA WL +S+D V + + N ERF S P +LG++ F G H WEV + Sbjct: 289 ITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDV 348 Query: 363 GGLQSWRVGVVRVRQDSGAEGHSHSCYHDTRSGFW--YVCRTQGVEGDHCVTSDPATSPL 420 G ++W +GV R +GH ++SGFW ++ Q E + P T PL Sbjct: 349 TGKEAWDLGV--CRDSVRRKGH---FLLSSKSGFWTIWLWNKQKYEAG----TYPQT-PL 398 Query: 421 VLAIPR-RLRVELECEEGELSFYDAERHCHL-YTFH--ARFGEVRPYFYLGGARGAGPPE 476 L +P ++ + L+ E G +SFY+ H L Y+F A G +RP+F G G Sbjct: 399 HLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFFSPGFNDGGKNTA 458 Query: 477 PLRICPLHISVKEELD 492 PL +CPL+I + D Sbjct: 459 PLTLCPLNIGSQGSTD 474 >gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens] Length = 488 Score = 181 bits (459), Expect = 1e-45 Identities = 140/473 (29%), Positives = 215/473 (45%), Gaps = 23/473 (4%) Query: 18 ELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWE-VQVSPTCPVCKDRASPADLRTNHTLN 76 E C+VC + ++ V + CGHNFC+ C++R WE ++ CPVC+ + LR N L Sbjct: 26 EASCSVCLEYLKEPVIIECGHNFCKACITRWWEDLERDFPCPVCRKTSRYRSLRPNRQLG 85 Query: 77 NLVEKLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQADPRHQGHRVQP 136 ++VE + +A + R +C H LSLFC ED+E +C C H+ H V P Sbjct: 86 SMVEIAKQLQAVKRK---IRDESLCPQHHEALSLFCYEDQEAVCLICAISHTHRAHTVVP 142 Query: 137 VKDTAHDFRAKCRNMEHALREKAKAFWAMRRSYEAIAKHNQVEAAWLEGRIRQEFDKLRE 196 + D +++ K + L +K + + S E + +I +EF++L Sbjct: 143 LDDATQEYKEKLQKCLEPLEQKLQEITRCKSSEEKKPGELKRLVESRRQQILREFEELHR 202 Query: 197 FLRVEEQAILDAMAEETRQKQLLADEKMKQLTEETEVLAHEIERLQMEMKEDDVSFLMKH 256 L E+Q +L + EE + E L ++ LAH ++ + + L Sbjct: 203 RLDEEQQVLLSRLEEEEQDILQRLRENAAHLGDKRRDLAHLAAEVEGKCLQSGFEMLKDV 262 Query: 257 KS--RKRRLFCTMEPEPVQPGMLIDVCKYLGSL--QYRVWKKMLASVESVPFSFDPNTAA 312 KS K TME V I++ K + QY +K+L + + DP TA Sbjct: 263 KSTLEKCEKVKTMEVTSVS----IELEKNFSNFPRQYFALRKILKQL-IADVTLDPETAH 317 Query: 313 GWLSVSDDLTSVTNHGYRVQ--VENPERFSSAPCLLGSRVFSQGSHAWEVALGGLQSWRV 370 L +S+D SV R++ + P RF+ PC+L + F+ G H WEV +G W V Sbjct: 318 PNLVLSEDRKSVKFVETRLRDLPDTPRRFTFYPCVLATEGFTSGRHYWEVEVGDKTHWAV 377 Query: 371 GVVRVRQDSGAEGHSHSCYHDTRSGFWYVCRTQGVEGDHCVTSDPATSPLVLAIPRRLRV 430 GV R DS + + +T G+W V G + T+ P T + P+R+ + Sbjct: 378 GVCR---DSVSRKGELTPLPET--GYWRVRLWNG--DKYAATTTPFTPLHIKVKPKRVGI 430 Query: 431 ELECEEGELSFYDAERHCHLYTFHARFGE-VRPYFYLGGARGAGPPEPLRICP 482 L+ E G LSFY+ H+YTF F E + P FY G G PL I P Sbjct: 431 FLDYEAGTLSFYNVTDRSHIYTFTDTFTEKLWPLFYPGIRAGRKNAAPLTIRP 483 >gi|22749269 ring finger protein 129 [Homo sapiens] Length = 471 Score = 178 bits (451), Expect = 1e-44 Identities = 141/482 (29%), Positives = 225/482 (46%), Gaps = 40/482 (8%) Query: 14 SFKEELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCW-EVQVSPTCPVCKDRASPADLRTN 72 + +EE C +C + +D VT+ CGHNFCR C+S W ++ + CPVC+ R N Sbjct: 9 NLQEESSCPICLEYLKDPVTINCGHNFCRSCLSVSWKDLDDTFPCPVCRFCFPYKSFRRN 68 Query: 73 HTLNNLVEKLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQADPRHQGH 132 L NL E + + ++ + + +C H L+LFC++D E+LC C +HQ H Sbjct: 69 PQLRNLTEIAKQLQIRRSKRKRQKENAMCEKHNQFLTLFCVKDLEILCTQCSFSTKHQKH 128 Query: 133 RVQPVKDTAHDFRAKCRNMEHALR---EKAKAFWAMRRSYEAIAKHNQVEAAWLEGRIRQ 189 + P+K A R LR E+ + ++ S +++ +VE + I Sbjct: 129 YICPIKKAASYHREILEGSLEPLRNNIERVEKVIILQGS-KSVELKKKVE--YKREEINS 185 Query: 190 EFDKLREFLRVEEQAILDAMAEETRQKQLLADEKMKQLTEETEVLAHEIERLQMEMKEDD 249 EF+++R FL+ E++ IL + +E +E + +L++ L H + ++ + + + Sbjct: 186 EFEQIRLFLQNEQEMILRQIQDEEMNILAKLNENLVELSDYVSTLKHLLREVEGKSVQSN 245 Query: 250 VSFLMKHKSRKRRLFCTMEPEPVQPGMLIDVCKYLGSL--QYRVWKKMLASVESVPFSFD 307 + L + KS + PE + KY SL QY +++ + V D Sbjct: 246 LELLTQAKSMHHKYQNLKCPELFS----FRLTKYGFSLPPQYSGLDRIIKPFQ-VDVILD 300 Query: 308 PNTAAGWLSVSDDLTSVTNHGYRVQV-ENPERFSSAPCLLGSRVFSQGSHAWEVALGGLQ 366 NTA L VS+D +V + + +P RF P +LGS+ FS G H WEV +G Sbjct: 301 LNTAHPQLLVSEDRKAVRYERKKRNICYDPRRFYVCPAVLGSQRFSSGRHYWEVEVGNKP 360 Query: 367 SWRVGV-----VRVRQDSGAEGHSHSCYHDTRSGFWYVCRTQGVEGDHCVTSDPATSPLV 421 W +GV +R QD + GFW + R V S P T+ L+ Sbjct: 361 KWILGVCQDCLLRNWQDQPS----------VLGGFWAIGRYM---KSGYVASGPKTTQLL 407 Query: 422 LAI-PRRLRVELECEEGELSFYDAERHCHLYTFHARFGE-VRPYFYLGGARGAGPPEPLR 479 + P ++ + L+ E G+LSFY+ LYTF+ F E V PYFY G EPL+ Sbjct: 408 PVVKPSKIGIFLDYELGDLSFYNMNDRSILYTFNDCFTEAVWPYFYTG-----TDSEPLK 462 Query: 480 IC 481 IC Sbjct: 463 IC 464 >gi|157743261 tripartite motif-containing 75 [Homo sapiens] Length = 468 Score = 178 bits (451), Expect = 1e-44 Identities = 136/476 (28%), Positives = 219/476 (46%), Gaps = 38/476 (7%) Query: 18 ELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCW-EVQVSPTCPVCKDRASPADLRTNHTLN 76 E C++C D D VT+ CGHNFCR C+ + W ++Q CPVC+ + R+N L Sbjct: 13 EAKCSICLDYLSDPVTIECGHNFCRSCIQQSWLDLQELFPCPVCRHQCQEGHFRSNTQLG 72 Query: 77 NLVE--KLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQADPRHQGHRV 134 ++E KLL+ R + +C H LS+FC ED +LC C P HQGH V Sbjct: 73 RMIEIAKLLQSTKSNKR--KQEETTLCEKHNQPLSVFCKEDLMVLCPLCTQPPDHQGHHV 130 Query: 135 QPVKDTAHDFRAKCRNMEHALREKAKAFWAM--RRSYEAIAKHNQVEAAWLEGRIRQEFD 192 +P++ A +R + + L+++ + +S + + VE E + EF+ Sbjct: 131 RPIEKAAIHYRKRFCSYIQPLKKQLADLQKLISTQSKKPLELREMVENQRQE--LSSEFE 188 Query: 193 KLREFLRVEEQAILDAMAEETRQKQLLADEKMKQLTEETEVLAHEIERLQMEMKEDDVSF 252 L +FL E+QA+L +AEE + Q + + + L ++ ++ + ++ Sbjct: 189 HLNQFLDREQQAVLSRLAEEEKDNQQKLSANITAFSNYSATLKSQLSKVVELSELSELEL 248 Query: 253 LMKHKSRKRRLFCTMEPEPVQPGMLI----DVCKYLGSLQYRVWKKMLASVESVPFSFDP 308 L + K +F E E I D C + QY ++++ + V DP Sbjct: 249 LSQIK-----IFYESENESSPSIFSIHLKRDGCSF--PPQYSALQRIIKKFK-VEIILDP 300 Query: 309 NTAAGWLSVSDDLTSVTNHGYRVQVEN-PERFSSAPCLLGSRVFSQGSHAWEVALGGLQS 367 TA L VS+D V + +V P+RF+ P +LG F G H WE+ +G Sbjct: 301 ETAHPNLIVSEDKKRVRFTKRKQKVPGFPKRFTVKPVVLGFPYFHSGRHFWEIEVGDKSE 360 Query: 368 WRVGVVRVRQDSGAEGHSHSCYHDTRSGFWYVCRTQGVEGDHCVTSDPATSPLVLAI-PR 426 W +G+ + + A S + W + +G H + P +PL+L + R Sbjct: 361 WAIGICKDSLPTKARRPS-----SAQQECWRIELQD--DGYHAPGAFP--TPLLLEVKAR 411 Query: 427 RLRVELECEEGELSFYDAERHCHLYTFHARF-GEVRPYFYLGGARGAGPPEPLRIC 481 + + L+ E GE+SFY+ H+ TF F G +RPYFY+G +PLRIC Sbjct: 412 AIGIFLDYEMGEISFYNMAEKSHICTFTDTFTGPLRPYFYVG-----PDSQPLRIC 462 >gi|5730009 ret finger protein [Homo sapiens] Length = 513 Score = 177 bits (448), Expect = 3e-44 Identities = 146/499 (29%), Positives = 227/499 (45%), Gaps = 48/499 (9%) Query: 16 KEELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCW-EVQVSPTCPVCKDRASPADLRTNHT 74 ++E C VC F + + L CGHN C C++RCW + + +CP C++ +R N Sbjct: 11 QQETTCPVCLQYFAEPMMLDCGHNICCACLARCWGTAETNVSCPQCRETFPQRHMRPNRH 70 Query: 75 LNN---LVEKLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQADPRHQG 131 L N LV++L E G VC HR L L+C ED+ +C C H+G Sbjct: 71 LANVTQLVKQLRTERPSGPGGEM----GVCEKHREPLKLYCEEDQMPICVVCDRSREHRG 126 Query: 132 HRVQPVKDTAHDFRAKCRNMEHALREKAKAFWAMRRSYEAIAKHNQVEAAWLEG-RIRQE 190 H V P+++ F+ + +N L+ + K RR+ A+ + +E +I E Sbjct: 127 HSVLPLEEAVEGFKEQIQNQLDHLK-RVKDLKKRRRAQGEQARAELLSLTQMEREKIVWE 185 Query: 191 FDKLREFLRVEEQAILDAMAEETRQKQLLADEKMKQLTEETEVLAHEIERLQMEMKE--- 247 F++L L+ E +L + E + + Q + L+ I +L+ + ++ Sbjct: 186 FEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIAQLEEKQQQPTR 245 Query: 248 ---DDVSFLMKHKSRKRRLFCTMEPEPVQPGMLI--DVCKYLGSLQYRVWKKMLASVE-- 300 D+ + R R + P +Q + I C +L + +KM + +E Sbjct: 246 ELLQDIGDTLSRAERIRIPEPWITPPDLQEKIHIFAQKCLFLTESLKQFTEKMQSDMEKI 305 Query: 301 ---------SVPFSFDPNTAAGWLSVSDDLTSVTNHGYRVQ--VENPERFSSAPCLLGSR 349 SV + DP+TA L +SD+L V + Y Q +NPERF+ PC+LGS Sbjct: 306 QELREAQLYSVDVTLDPDTAYPSLILSDNLRQV-RYSYLQQDLPDNPERFNLFPCVLGSP 364 Query: 350 VFSQGSHAWEVALGGLQSWRVGVVRVRQDSGAEGHSHSCYHDTRSGFWYVCRTQGVEGDH 409 F G H WEV +G W +GV +DS ++GFW V G E + Sbjct: 365 CFIAGRHYWEVEVGDKAKWTIGVC---EDSVC--RKGGVTSAPQNGFWAVSLWYGKE--Y 417 Query: 410 CVTSDPATSPLVLAIPRRLRVELECEEGELSFYDAERHCHLYTF-HARF-GEVRPYF--- 464 + P T+ + +R+ + L+ + GE+SFY+ CH +TF HA F G VRPYF Sbjct: 418 WALTSPMTALPLRTPLQRVGIFLDYDAGEVSFYNVTERCHTFTFSHATFCGPVRPYFSLS 477 Query: 465 YLGGARGAGPPEPLRICPL 483 Y GG A PL ICP+ Sbjct: 478 YSGGKSAA----PLIICPM 492 >gi|217035095 tripartite motif-containing 62 [Homo sapiens] Length = 475 Score = 176 bits (445), Expect = 6e-44 Identities = 133/489 (27%), Positives = 221/489 (45%), Gaps = 34/489 (6%) Query: 14 SFKEELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCW---EVQVSPTCPVCKDRASPADLR 70 S K+ELLC++C ++D V+L C H FCR C++ W E Q + CP C+ + L Sbjct: 4 SLKDELLCSICLSIYQDPVSLGCEHYFCRRCITEHWVRQEAQGARDCPECRRTFAEPALA 63 Query: 71 TNHTLNNLVEKLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQADPRHQ 130 + L N+VE+ + A + R +R C+ H ++ LFCL D+ LLC C H+ Sbjct: 64 PSLKLANIVERYSSFPLD-AILNARRAARPCQAH-DKVKLFCLTDRALLCFFCDEPALHE 121 Query: 131 GHRVQPVKDTAHDFRAKCRNMEHALREKAKAFWAMRRSYEAIAKHNQVEAAWLEGRIRQE 190 H+V + D + + + ++ AL++ + + + + L I + Sbjct: 122 QHQVTGIDDAFDELQRELKDQLQALQDSEREHTEALQLLKRQLAETKSSTKSLRTTIGEA 181 Query: 191 FDKLREFLRVEEQAILDAMAEETRQKQLLADEKMKQLTEETEVLAHEIERLQMEMKEDD- 249 F++L LR ++A+L+ + +T + ++K+++ +++ + + LQ + E D Sbjct: 182 FERLHRLLRERQKAMLEELEADTARTLTDIEQKVQRYSQQLRKVQEGAQILQERLAETDR 241 Query: 250 -------VSFLMKHKSRKRRLFCTMEPEPVQPGMLIDVCKYLGSLQYRVWKKMLASVESV 302 S + K + T E P KY G LQY +WK + + V Sbjct: 242 HTFLAGVASLSERLKGKIHETNLTYEDFPTS--------KYTGPLQYTIWKSLFQDIHPV 293 Query: 303 P--FSFDPNTAAGWLSVSDDLTSVTNHGYRVQ--VENPERFSSAPCLLGSRVFSQGSHAW 358 P + DP TA L +SDD T V Q ++P+RF +LGS FS G H W Sbjct: 294 PAALTLDPGTAHQRLILSDDCTIVAYGNLHPQPLQDSPKRFDVEVSVLGSEAFSSGVHYW 353 Query: 359 EVALGGLQSWRVGVVRVRQDSGAEGHSHSCYHDTRSGFWYVCRTQGVEGDHCVTSDPATS 418 EV + W +G+ A S GF+ + G + C ++P T Sbjct: 354 EVVVAEKTQWVIGLAH-----EAASRKGSIQIQPSRGFYCIVMHDGNQYSAC--TEPWTR 406 Query: 419 PLVLAIPRRLRVELECEEGELSFYDAERHCHLYTFHARF-GEVRPYFYLGGARGAGP-PE 476 V ++ V L+ ++G L FY+A+ LYTF +F G++ YF G + G + Sbjct: 407 LNVRDKLDKVGVFLDYDQGLLIFYNADDMSWLYTFREKFPGKLCSYFSPGQSHANGKNVQ 466 Query: 477 PLRICPLHI 485 PLRI + I Sbjct: 467 PLRINTVRI 475 >gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens] Length = 518 Score = 174 bits (442), Expect = 1e-43 Identities = 144/500 (28%), Positives = 226/500 (45%), Gaps = 47/500 (9%) Query: 18 ELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWE-VQVSPTCPVCKDRASPADLRTNHTLN 76 E C+VC + ++ V + CGHNFC+ C++R WE ++ CPVC+ + LR N L Sbjct: 26 EASCSVCLEYLKEPVIIECGHNFCKACITRWWEDLERDFPCPVCRKTSRYRSLRPNRQLG 85 Query: 77 NLVEKLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQADPRHQGHRVQP 136 ++VE + +A + R +C H LSLFC ED+E +C C H+ H V P Sbjct: 86 SMVEIAKQLQAVKRK---IRDESLCPQHHEALSLFCYEDQEAVCLICAISHTHRAHTVVP 142 Query: 137 VKDTAHDFRAKCRNMEHALREKAKAFWAMRRSYEAIAKHNQVEAAWLEGRIRQEFDKLRE 196 + D +++ K + L +K + + S E + +I +EF++L Sbjct: 143 LDDATQEYKEKLQKCLEPLEQKLQEITRCKSSEEKKPGELKRLVESRRQQILREFEELHR 202 Query: 197 FLRVEEQAILDAMAEETRQKQLLADEKMKQLTEETEVLAH---EIE----RLQMEMKEDD 249 L E+Q +L + EE + E L ++ LAH E+E + EM +D Sbjct: 203 RLDEEQQVLLSRLEEEEQDILQRLRENAAHLGDKRRDLAHLAAEVEGKCLQSGFEMLKDV 262 Query: 250 VSFLMKHKSRK----RRLFCTMEPEPVQPGML--IDVCKYLGSL---------------- 287 S L K+ RK C + + + G++ I+ C+ + ++ Sbjct: 263 KSTLEKNIPRKFGGSLSTICPRDHKALL-GLVKEINRCEKVKTMEVTSVSIELEKNFSNF 321 Query: 288 --QYRVWKKMLASVESVPFSFDPNTAAGWLSVSDDLTSVTNHGYRVQ--VENPERFSSAP 343 QY +K+L + + DP TA L +S+D SV R++ + P RF+ P Sbjct: 322 PRQYFALRKILKQL-IADVTLDPETAHPNLVLSEDRKSVKFVETRLRDLPDTPRRFTFYP 380 Query: 344 CLLGSRVFSQGSHAWEVALGGLQSWRVGVVRVRQDSGAEGHSHSCYHDTRSGFWYVCRTQ 403 C+L + F+ G H WEV +G W VGV R DS + + +T G+W V Sbjct: 381 CVLATEGFTSGRHYWEVEVGDKTHWAVGVCR---DSVSRKGELTPLPET--GYWRVRLWN 435 Query: 404 GVEGDHCVTSDPATSPLVLAIPRRLRVELECEEGELSFYDAERHCHLYTFHARFGE-VRP 462 G + T+ P T + P+R+ + L+ E G LSFY+ H+YTF F E + P Sbjct: 436 G--DKYAATTTPFTPLHIKVKPKRVGIFLDYEAGTLSFYNVTDRSHIYTFTDTFTEKLWP 493 Query: 463 YFYLGGARGAGPPEPLRICP 482 FY G G PL I P Sbjct: 494 LFYPGIRAGRKNAAPLTIRP 513 >gi|112421127 tripartite motif-containing 58 [Homo sapiens] Length = 486 Score = 172 bits (436), Expect = 6e-43 Identities = 136/473 (28%), Positives = 208/473 (43%), Gaps = 45/473 (9%) Query: 11 PSRSFKEELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWEVQVSP-----TCPVCKDRAS 65 P +E+ C VC D ++ V++ CGH+FC C+S E CP C+ Sbjct: 6 PGERLREDARCPVCLDFLQEPVSVDCGHSFCLRCISEFCEKSDGAQGGVYACPQCRGPFR 65 Query: 66 PADLRTNHTLNNLVEKLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQA 125 P+ R N L LVE + R +R C H LS FC ED+ LC C A Sbjct: 66 PSGFRPNRQLAGLVESVRRLGLGAGPG-----ARRCARHGEDLSRFCEEDEAALCWVCDA 120 Query: 126 DPRHQGHRVQPVKDTAHDFRAKC--------RNMEHALREKAKAFWAMRRSYEAIAKHNQ 177 P H+ HR P+++ A ++ K + +E AL ++A + + + Sbjct: 121 GPEHRTHRTAPLQEAAGSYQVKLQMALELMRKELEDALTQEANV------GKKTVIWKEK 174 Query: 178 VEAAWLEGRIRQEFDKLREFLRVEEQAILDAMAEETRQKQLLADEKMKQLTEETEVLAHE 237 VE R R EF+K R FL EEQ L + E R E +L ++++ L Sbjct: 175 VEMQ--RQRFRLEFEKHRGFLAQEEQRQLRRLEAEERATLQRLRESKSRLVQQSKALKEL 232 Query: 238 IERLQMEMKEDDVSFL--MKHKSRKRRLFCTMEPEPVQPGMLIDVCKYLGSLQYRVWKKM 295 + LQ + + L ++ + + +E E + P L C G ++ Sbjct: 233 ADELQERCQRPALGLLEGVRGVLSRSKAVTRLEAENI-PMELKTACCIPG-------RRE 284 Query: 296 LASVESVPFSFDPNTAAGWLSVSDDLTSVTN-HGYRVQVENPERFSSAPCLLGSRVFSQG 354 L V DP TA L ++ DL SV + +R NPERF + PC+LG + FS G Sbjct: 285 LLRKFQVDVKLDPATAHPSLLLTADLRSVQDGEPWRDVPNNPERFDTWPCILGLQSFSSG 344 Query: 355 SHAWEVALGGLQSWRVGVVRVRQDSGAEGHSHSCYHDTRSGFWYVCRTQGVEGDHCVTSD 414 H WEV +G W +GV + E +G W + +G ++ V + Sbjct: 345 RHYWEVLVGEGAEWGLGVCQDTLPRKGE-----TTPSPENGVWALWLLKG--NEYMVLAS 397 Query: 415 PATSPLVLAIPRRLRVELECEEGELSFYDAERHCHLYTFHARF-GEVRPYFYL 466 P+ L L PR + + L+ E GE+SFY+ ++YTF+ F G +RPYF++ Sbjct: 398 PSVPLLQLESPRCIGIFLDYEAGEISFYNVTDGSYIYTFNQLFSGLLRPYFFI 450 >gi|88999601 tripartite motif-containing 69 isoform a [Homo sapiens] Length = 500 Score = 166 bits (421), Expect = 3e-41 Identities = 142/483 (29%), Positives = 215/483 (44%), Gaps = 44/483 (9%) Query: 18 ELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWEVQVSPT-CPVCKDRASPADLRTNHTLN 76 EL C +C D FRD + L CGHNFC C+ W +Q T CP CK + N L+ Sbjct: 38 ELHCPLCNDWFRDPLMLSCGHNFCEACIQDFWRLQAKETFCPECKMLCQYNNCTFNPVLD 97 Query: 77 NLVEKLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQADPR---HQGHR 133 LVEK+ + + C H L LF D +L+C C+ D R Q Sbjct: 98 KLVEKI-------KKLPLLKGHPQCPEHGENLKLFSKPDGKLICFQCK-DARLSVGQSKE 149 Query: 134 VQPVKDTAHDFRAKCRNMEHALREKAKAFWAMRR-SYEAIAKHNQVEAAWLEGRIRQEFD 192 + D H F + + L K +R EAIA H + L+ + EF Sbjct: 150 FLQISDAVHFFTEELAIQQGQLETTLKELQTLRNMQKEAIAAHKE-NKLHLQQHVSMEFL 208 Query: 193 KLREFLRVEEQAILDAMAEETRQKQLLADEKMKQLTEETEVLAHEIERLQMEMKED---- 248 KL +FL +E+ IL + EE + + + QL E+ + + +Q + ++ Sbjct: 209 KLHQFLHSKEKDILTELREEGKALNEEMELNLSQLQEQCLLAKDMLVSIQAKTEQQNSFD 268 Query: 249 ---DVSFLMKHKSRKRRLFCTMEPEPVQPGMLIDVCKYLGSLQYRVWKKMLASV--ESVP 303 D++ L+ + ++ T E +++ +Y G +QY VW++M ++ P Sbjct: 269 FLKDITTLLHSLEQGMKVLATRE----LISRKLNLGQYKGPIQYMVWREMQDTLCPGLSP 324 Query: 304 FSFDPNTAAGWLSVSDDLTSVTNHG--YRVQVENPERFSSAPCLLGSRVFSQGSHAWEVA 361 + DP TA L +S TSV HG ++ ++PERF S+ +LGSR F+ G WEV Sbjct: 325 LTLDPKTAHPNLVLSKSQTSVW-HGDIKKIMPDDPERFDSSVAVLGSRGFTSGKWYWEVE 383 Query: 362 LGGLQSWRVGVVR---VRQDSGAEGHSHSCYHDTRSGFWYVCRTQGVEGDHCVTSDPATS 418 + W VGVVR +R+ SC GFW + + D P+ S Sbjct: 384 VAKKTKWTVGVVRESIIRKG--------SCPLTPEQGFWLLRLRN--QTDLKALDLPSFS 433 Query: 419 PLVLAIPRRLRVELECEEGELSFYDAERHCHLYTFHARFGE-VRPYFYLGGARGAGPPEP 477 + ++ + L+ E G+LSFY+A+ H+YTF F E + PYF G EP Sbjct: 434 LTLTNNLDKVGIYLDYEGGQLSFYNAKTMTHIYTFSNTFMEKLYPYFCPCLNDGGENKEP 493 Query: 478 LRI 480 L I Sbjct: 494 LHI 496 >gi|44680122 tripartite motif-containing 7 isoform 1 [Homo sapiens] Length = 511 Score = 166 bits (419), Expect = 6e-41 Identities = 139/488 (28%), Positives = 206/488 (42%), Gaps = 56/488 (11%) Query: 18 ELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWE----------VQVSP---TCPVCKDRA 64 E C++C + FR+ V++ CGH+FCR C+ RCWE + P CP C++ A Sbjct: 26 EATCSICLELFREPVSVECGHSFCRACIGRCWERPGAGSVGAATRAPPFPLPCPQCREPA 85 Query: 65 SPADLRTNHTLNNLVEKLLR------------EEAEGARWTSYRFSRVCRLHRGQLSLFC 112 P+ LR N L + L R +A AR + R C H L+C Sbjct: 86 RPSQLRPNRQLAAVATLLRRFSLPAAAPGEHGSQAAAARAAAAR----CGQHGEPFKLYC 141 Query: 113 LEDKELLCCSCQADPRHQGHRVQPVKDTAHDFRAKCRNMEHALREKAKAFWAMRRSYEAI 172 +D +C C H+ H V P+ + + + + L+++ + R + + Sbjct: 142 QDDGRAICVVCDRAREHREHAVLPLDEAVQEAKELLESRLRVLKKELEDCEVFRSTEKKE 201 Query: 173 AKHNQVEAAWLEGRIRQEFDKLREFLRVEEQAILDAMAEETRQKQLLADEKMKQLTEETE 232 +K + A + ++ EF LR FL +E +L + E +R+ +E + QL E Sbjct: 202 SKELLKQMAAEQEKVGAEFQALRAFLVEQEGRLLGRLEELSREVAQKQNENLAQLGVEIT 261 Query: 233 VLAHEIERLQMEMKEDDVSFLMKHKSRKRRLFCTMEPEPVQPGMLIDVCKYLGSLQYRVW 292 L+ ++Q ++ D+ FL + KS R P+P + + SL+ V Sbjct: 262 QLSKLSSQIQETAQKPDLDFLQEFKSTLSRCSNVPGPKPTTVSSEMKNKVWNVSLKTFVL 321 Query: 293 KKMLASV-----------ESVPFSFDPNTAAGWLSVSDDLTSVTNHGYRVQ--VENPERF 339 K ML E V + DP+TA L +S DL V G R Q +P RF Sbjct: 322 KGMLKKFKEDLRGELEKEEKVELTLDPDTANPRLILSLDLKGV-RLGERAQDLPNHPCRF 380 Query: 340 SSAPCLLGSRVFSQGSHAWEVALGGLQSWRVGVVR--VRQDSGAEGHSHSCYHDTRSGFW 397 + +L S FS G H WEV +G W GV R VR+ G W Sbjct: 381 DTNTRVLASCGFSSGRHHWEVEVGSKDGWAFGVARESVRRKGLTP-------FTPEEGVW 433 Query: 398 YVCRTQGVEGDHCVTSDPATSPLVLAIPRRLRVELECEEGELSFYDAERHCHLYTFHARF 457 + Q G + + P SPL R+RV L+ E G +SFY E HLYTF F Sbjct: 434 AL---QLNGGQYWAVTSPERSPLSCGHLSRVRVALDLEVGAVSFYAVEDMRHLYTFRVNF 490 Query: 458 GE-VRPYF 464 E V P F Sbjct: 491 QERVFPLF 498 >gi|37622899 ring finger protein 137 [Homo sapiens] Length = 485 Score = 164 bits (416), Expect = 1e-40 Identities = 136/494 (27%), Positives = 224/494 (45%), Gaps = 51/494 (10%) Query: 17 EELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWEVQVSP-----TCPVCKDRASPADLRT 71 EE+ C +C R+ +++ CGH+FC C+S WE+ TCP+C+ P +LR Sbjct: 12 EEVACPICMTFLREPMSIDCGHSFCHSCLSGLWEIPGESQNWGYTCPLCRAPVQPRNLRP 71 Query: 72 NHTLNNLVEK--LLR-EEAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQADPR 128 N L N+VEK LLR G + +C H +L +FC ED ++C +C P Sbjct: 72 NWQLANVVEKVRLLRLHPGMGLK------GDLCERHGEKLKMFCKEDVLIMCEACSQSPE 125 Query: 129 HQGHRVQPVKDTAHDFRAKCRN-MEHALREKAKAFWAMRRSYEAIAKHNQVEAAWLEGRI 187 H+ H V P++D A +++ + +EH +E+ +A W + +++ + I Sbjct: 126 HEAHSVVPMEDVAWEYKWELHEALEHLKKEQEEA-WKLEVGERKRTATWKIQVETRKQSI 184 Query: 188 RQEFDKLREFLR----------VEEQAILDAMAEETRQKQLLADEKMKQLTEETEVLAHE 237 EF+K + L E A L ++ E + + +L ++++VL Sbjct: 185 VWEFEKYQRLLEKKQPPHRQLGAEVAAALASLQREAAETMQKLELNHSELIQQSQVLWRM 244 Query: 238 IERLQMEMKEDDVSFLM---KHKSRKRRLFCTMEPEPVQPGMLIDVCKYLGSLQYRVWKK 294 I L+ E + V +++ + + + + +PEP+ + D C+ LG + + K Sbjct: 245 IAELK-ERSQRPVRWMLQDIQEVLNRSKSWSLQQPEPISLELKTD-CRVLGLRE--ILKT 300 Query: 295 MLASVESVPFSFDPNTAAGWLSVSDDLTSVTNHGYRVQ--VENPERFSSAPCLLGSRVFS 352 A V DP+TA L VS+D V ++G Q +NPERF +LGS+ S Sbjct: 301 YAADVR-----LDPDTAYSRLIVSEDRKRV-HYGDTNQKLPDNPERFYRYNIVLGSQCIS 354 Query: 353 QGSHAWEVALGGLQSWRVGVVRVRQDSGAEGHSHSCYHDTRSGFWYVCRTQGVEGDHCVT 412 G H WEV +G W +GV + D Y GFW + +G E Sbjct: 355 SGRHYWEVEVGDRSEWGLGVCKQNVD-----RKEVVYLSPHYGFWVIRLRKGNEYRAGTD 409 Query: 413 SDPATSPLVLAIPRRLRVELECEEGELSFYD-AERHCHLYTF--HARFGEVRPYFYLGGA 469 P S + PRR+ + ++ E ++SFY+ + H++TF + G + PYF + Sbjct: 410 EYPILS--LPVPPRRVGIFVDYEAHDISFYNVTDCGSHIFTFPRYPFPGRLLPYFSPCYS 467 Query: 470 RGAGPPEPLRICPL 483 G PL IC L Sbjct: 468 IGTNNTAPLAICSL 481 >gi|30023818 tripartite motif protein 50A [Homo sapiens] Length = 487 Score = 159 bits (401), Expect = 7e-39 Identities = 137/469 (29%), Positives = 202/469 (43%), Gaps = 55/469 (11%) Query: 19 LLCAVCYDPFRDAVTLRCGHNFCRGC-VSRCWEVQVSPTCPVCKDRASPADLRTNHTLNN 77 L C +C + F++ + L+CGH++C+GC VS + CPVC+ + N +L Sbjct: 14 LQCPICLEVFKEPLMLQCGHSYCKGCLVSLSCHLDAELRCPVCRQAVDGSSSLPNVSLAR 73 Query: 78 LVEKLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQADPRHQGHRVQPV 137 ++E L R +VC HR LSLFC +D+EL+C C HQ H V PV Sbjct: 74 VIEAL--------RLPGDPEPKVCVHHRNPLSLFCEKDQELICGLCGLLGSHQHHPVTPV 125 Query: 138 KDTAHDFRAKCRNMEHALREKAKAFWAMRRSYEAIAK--HNQV----EAAWLEGRIRQEF 191 + + + L+++ K + E IAK +N+ E+ IR+EF Sbjct: 126 STVYSRMKEELAALISELKQEQK------KVDELIAKLVNNRTRIVNESDVFSWVIRREF 179 Query: 192 DKLREFLRVEEQAILDAMAEETRQKQLLADEKMKQLTEETEVLAHEIERLQMEMKEDDVS 251 +L + E+ L+ + TR D +++Q E LA L+ ED Sbjct: 180 QELHHLVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERLAQAECVLEQFGNEDHHK 239 Query: 252 FLMKHKS--------RKRRLFCTMEPEPVQPGMLIDVCKYLGSLQYRVWKKMLASVESVP 303 F+ K S + R L P +PG+ + ++ VWK++ V P Sbjct: 240 FIRKFHSMASRAEMPQARPLEGAFSPISFKPGL------HQADIKLTVWKRLFRKVLPAP 293 Query: 304 --FSFDPNTAAGWLSVSDDLTSVTNHGYRVQ--VENPERFSSAPCLLGSRVFSQGSHAWE 359 DP TA L +S T V G Q PERF + C+L SR FS G H WE Sbjct: 294 EPLKLDPATAHPLLELSKGNT-VVQCGLLAQRRASQPERFDYSTCVLASRGFSCGRHYWE 352 Query: 360 VALGGLQSWRVGVVRVRQDSGAEGHSHSCYHDTRSGFWYVCRTQG--VEGDHCVTSDPAT 417 V +G WR+GV++ G G W + +G E C P Sbjct: 353 VVVGSKSDWRLGVIK-----GTASRKGKLNRSPEHGVWLIGLKEGRVYEAFAC----PRV 403 Query: 418 SPLVLAIPRRLRVELECEEGELSFYDAERHCH---LYTFHARF-GEVRP 462 V P R+ + L E+GEL+F+DA+R LYTF A F G++ P Sbjct: 404 PLPVAGHPHRIGLYLHYEQGELTFFDADRPDDLRPLYTFQADFQGKLYP 452 >gi|68160933 tripartite motif-containing 17 isoform 1 [Homo sapiens] Length = 477 Score = 153 bits (386), Expect = 4e-37 Identities = 130/492 (26%), Positives = 214/492 (43%), Gaps = 69/492 (14%) Query: 12 SRSFKEELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWEV----------QVSPTCPVCK 61 +R +EE C++C D F D V CGHNFCR C+ WE + S CP C+ Sbjct: 7 ARKLQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSWEKARGKKGRRKRKGSFPCPECR 66 Query: 62 DRASPADLRTNHTLNNLVEKLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLCC 121 + + +L N L + E + ++ G + +C+ H L LFC +D+ +C Sbjct: 67 EMSPQRNLLPNRLLTKVAE--MAQQHPGLQKQD-----LCQEHHEPLKLFCQKDQSPICV 119 Query: 122 SCQADPRHQGHRVQPVKDTAHDFRAKCRNMEHALREKAKAFWAMRRSYEAIAKHNQVEAA 181 C+ H+ HRV P ++ ++ K LRE+ + R+ A+ Q A Sbjct: 120 VCRESREHRLHRVLPAEEAVQGYKLKLEEDMEYLREQ------ITRTGNLQAREEQSLAE 173 Query: 182 WLEGRIRQ-------EFDKLREFLRVEEQAILDAMAEETRQKQLLADEKMKQLTEETEVL 234 W +G++++ EF+K+ +L EEQ +L A+ E + E + L + Sbjct: 174 W-QGKVKERRERIVLEFEKMNLYLVEEEQRLLQALETEEEETASRLRESVACLDRQ---- 228 Query: 235 AHEIERLQMEMKEDDVSFL------MKHKSRKRRLFCTMEPEPVQPGMLIDVCKYLGSLQ 288 H +E L ++++E MK ++ PE P VC+ G Q Sbjct: 229 GHSLELLLLQLEERSTQGPLQMLQDMKEPLSRKNNVSVQCPEVAPPTRPRTVCRVPG--Q 286 Query: 289 YRVWKKMLASVESVPFSFDPNTAAGWLSVSDDL------TSVTNHGYRVQVENPERFSSA 342 V + L V VP D +A +L + + +S G+ + +RF + Sbjct: 287 IEVLRGFLEDV--VP---DATSAYPYLLLYESRQRRYLGSSPEGSGFC----SKDRFVAY 337 Query: 343 PCLLGSRVFSQGSHAWEVALG--GLQSWRVGVVRVRQDSGAEGHSHSCYHDTRSGFWYVC 400 PC +G FS G H WEV + G W +GV R + + C +GFW V Sbjct: 338 PCAVGQTAFSSGRHYWEVGMNITGDALWALGV--CRDNVSRKDRVPKC---PENGFWVVQ 392 Query: 401 RTQGVEGDHCVTSDPATSPLVLAIPRRLRVELECEEGELSFYDAERHCHLYTF-HARF-G 458 ++G + + T T +++ P + + L+ E GE+SFY HL+T+ A F G Sbjct: 393 LSKGTK--YLSTFSALTPVMLMEPPSHMGIFLDFEAGEVSFYSVSDGSHLHTYSQATFPG 450 Query: 459 EVRPYFYLGGAR 470 ++P+F LG + Sbjct: 451 PLQPFFCLGAPK 462 >gi|7705825 tripartite motif-containing 17 isoform 1 [Homo sapiens] Length = 477 Score = 153 bits (386), Expect = 4e-37 Identities = 130/492 (26%), Positives = 214/492 (43%), Gaps = 69/492 (14%) Query: 12 SRSFKEELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWEV----------QVSPTCPVCK 61 +R +EE C++C D F D V CGHNFCR C+ WE + S CP C+ Sbjct: 7 ARKLQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSWEKARGKKGRRKRKGSFPCPECR 66 Query: 62 DRASPADLRTNHTLNNLVEKLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLCC 121 + + +L N L + E + ++ G + +C+ H L LFC +D+ +C Sbjct: 67 EMSPQRNLLPNRLLTKVAE--MAQQHPGLQKQD-----LCQEHHEPLKLFCQKDQSPICV 119 Query: 122 SCQADPRHQGHRVQPVKDTAHDFRAKCRNMEHALREKAKAFWAMRRSYEAIAKHNQVEAA 181 C+ H+ HRV P ++ ++ K LRE+ + R+ A+ Q A Sbjct: 120 VCRESREHRLHRVLPAEEAVQGYKLKLEEDMEYLREQ------ITRTGNLQAREEQSLAE 173 Query: 182 WLEGRIRQ-------EFDKLREFLRVEEQAILDAMAEETRQKQLLADEKMKQLTEETEVL 234 W +G++++ EF+K+ +L EEQ +L A+ E + E + L + Sbjct: 174 W-QGKVKERRERIVLEFEKMNLYLVEEEQRLLQALETEEEETASRLRESVACLDRQ---- 228 Query: 235 AHEIERLQMEMKEDDVSFL------MKHKSRKRRLFCTMEPEPVQPGMLIDVCKYLGSLQ 288 H +E L ++++E MK ++ PE P VC+ G Q Sbjct: 229 GHSLELLLLQLEERSTQGPLQMLQDMKEPLSRKNNVSVQCPEVAPPTRPRTVCRVPG--Q 286 Query: 289 YRVWKKMLASVESVPFSFDPNTAAGWLSVSDDL------TSVTNHGYRVQVENPERFSSA 342 V + L V VP D +A +L + + +S G+ + +RF + Sbjct: 287 IEVLRGFLEDV--VP---DATSAYPYLLLYESRQRRYLGSSPEGSGFC----SKDRFVAY 337 Query: 343 PCLLGSRVFSQGSHAWEVALG--GLQSWRVGVVRVRQDSGAEGHSHSCYHDTRSGFWYVC 400 PC +G FS G H WEV + G W +GV R + + C +GFW V Sbjct: 338 PCAVGQTAFSSGRHYWEVGMNITGDALWALGV--CRDNVSRKDRVPKC---PENGFWVVQ 392 Query: 401 RTQGVEGDHCVTSDPATSPLVLAIPRRLRVELECEEGELSFYDAERHCHLYTF-HARF-G 458 ++G + + T T +++ P + + L+ E GE+SFY HL+T+ A F G Sbjct: 393 LSKGTK--YLSTFSALTPVMLMEPPSHMGIFLDFEAGEVSFYSVSDGSHLHTYSQATFPG 450 Query: 459 EVRPYFYLGGAR 470 ++P+F LG + Sbjct: 451 PLQPFFCLGAPK 462 >gi|15011941 tripartite motif protein TRIM4 isoform beta [Homo sapiens] Length = 474 Score = 145 bits (365), Expect = 1e-34 Identities = 132/479 (27%), Positives = 191/479 (39%), Gaps = 46/479 (9%) Query: 12 SRSFKEELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWEVQVSP-TCPVCKDRASPADLR 70 + +EEL C +C D F+D V++ CGHNFCRGC+ R W P CP C+ ++PA LR Sbjct: 3 AEDIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSAPAALR 62 Query: 71 TNHTLNNLVEKLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQADPRHQ 130 N L L EK R +C H L LFC +D+ +C C+ HQ Sbjct: 63 PNWALARLTEKTQRRRLGPVP------PGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQ 116 Query: 131 GHRVQPVKDTAHDFRAKCRNMEHALREKAKAFWAMRRSYEAIAKHNQVEAAWLEGRIRQE 190 H + P+ + +R K + L K K ++ A + + RI E Sbjct: 117 THAMAPIDEAFESYREKLLKSQRNLVAKMKKVMHLQDVEVKNATQWKDKIKSQRMRISTE 176 Query: 191 FDKLREFLRVEEQAILDAMAEETRQKQLLADEKMKQLTEETEVLAHEI---ERLQMEMKE 247 F KL FL EE L + +E +E K+L E T L I ++L +E+ E Sbjct: 177 FSKLHNFLVEEEDLFLQRLNKE-------EEETKKKLNENTLKLNQTIASLKKLILEVGE 229 Query: 248 DDVSFLMKHKSRKRRLFCTMEPEPVQPGMLIDVCKYLGSLQYRVWKKMLASVESVPFSFD 307 + ++ + + E + V ++ K Q + K+ML + V + Sbjct: 230 KSQAPTLELLQNPKEVLTRSEIQDV--NYSLEAVKVKTVCQIPLMKEMLKRFQ-VAVNLA 286 Query: 308 PNTAAGWLSVSDDLTSVTN-------------HGYRVQVENP------ERFSSAPCLLGS 348 +TA L S + V N Y NP ERF PC+LG Sbjct: 287 EDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAGWRNPQKTAFVERFQHLPCVLGK 346 Query: 349 RVFSQGSHAWEVALGGLQSWRVGVVRVRQDSGAEGHSHSCYHDTRSGFWYVCRTQGVEGD 408 VF+ G H WEV VGV R G + G W + G Sbjct: 347 NVFTSGKHYWEVESRDSLEVAVGVCR----EDVMGITDRSKMSPDVGIWAI--YWSAAGY 400 Query: 409 HCVTSDPATSPLVLAIPRRLRVELECEEGELSFYDAERHCHLYTFH-ARFGEVRPYFYL 466 + P T R+ V L+ G +SFY A HL+TF + +RP+F+L Sbjct: 401 WPLIGFPGTPTQQEPALHRVGVYLDRGTGNVSFYSAVDGVHLHTFSCSSVSRLRPFFWL 459 >gi|157426898 tripartite motif-containing 10 isoform 1 [Homo sapiens] Length = 481 Score = 144 bits (364), Expect = 1e-34 Identities = 132/486 (27%), Positives = 213/486 (43%), Gaps = 53/486 (10%) Query: 14 SFKEELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWEV-----QVSPTCPVCKDRASPAD 68 S +E+ C +C R+ VT+ CGHNFCR C++R E+ + SPTCP+CK+ P Sbjct: 9 SLADEVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLCKEPFRPGS 68 Query: 69 LRTNHTLNNLVEKLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQADPR 128 R N L N+VE + E + VC+ H ++ FC +D+ LC C+ Sbjct: 69 FRPNWQLANVVENI--ERLQLVSTLGLGEEDVCQEHGEKIYFFCEDDEMQLCVVCREAGE 126 Query: 129 HQGHRVQPVKDTAHDFRAKCRNMEHALREKAKAFWAMRRSYEAIAKHNQVEAAWLEGRIR 188 H H ++ ++D A +R + LR++ + ++ + + + ++ Sbjct: 127 HATHTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQSRENKRMQVLLTQVSTKRQQVI 186 Query: 189 QEFDKLREFLRVEEQAILDAMAEE-----TRQK---QLLADEKMKQLTEETEVLAHEIER 240 EF LR+FL E+Q+IL A E RQ+ LL ++ + + E L + ER Sbjct: 187 SEFAHLRKFLE-EQQSILLAQLESQDGDILRQRDEFDLLVAGEICRFSALIEELEEKNER 245 Query: 241 LQMEMKEDDVSFLMKHKSRKRRLFCTMEPE-------------PVQPGMLIDVCKYLGSL 287 E+ D S L++ ++RK R + PE P+Q M + + K L Sbjct: 246 PARELLTDIRSTLIRCETRKCRKPVAVSPELGQRIRDFPQQALPLQREMKMFLEKLCFEL 305 Query: 288 QYRVWKKMLASVESVPFSFDPNTAAGWLSVSDD-LTSVTNHGYRVQVENPERFSSAPCLL 346 Y E S DP T+ L +S+D + ++ ++ +NP+RF A C+L Sbjct: 306 DY----------EPAHISLDPQTSHPKLLLSEDHQRAQFSYKWQNSPDNPQRFDRATCVL 355 Query: 347 GSRVFSQGSHAWEVALGGLQSWRVGVVRVRQDSGAEGHSHSCYHDTRSGFWYVCRTQGVE 406 + G H W V++ V V +D +G G W V G Sbjct: 356 AHTGITGGRHTWVVSIDLAHGGSCTVGVVSEDVQRKGELRL---RPEEGVWAVRLAWG-- 410 Query: 407 GDHCVTSDPATSPLVLAI---PRRLRVELECEEGELSFYDAERHCHLYTFHARF-GEVRP 462 S + P L + PR++RV L+ E G ++F +A +YTF A F +V P Sbjct: 411 ----FVSALGSFPTRLTLKEQPRQVRVSLDYEVGWVTFTNAVTREPIYTFTASFTRKVIP 466 Query: 463 YFYLGG 468 +F L G Sbjct: 467 FFGLWG 472 >gi|5454014 tripartite motif-containing 38 [Homo sapiens] Length = 465 Score = 141 bits (355), Expect = 2e-33 Identities = 120/467 (25%), Positives = 205/467 (43%), Gaps = 37/467 (7%) Query: 12 SRSFKEELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWEV-------QVSPTCPVCKDRA 64 ++ EE C++C + V++ CGH++C C++ ++ Q + CP C+ Sbjct: 7 TKKMMEEATCSICLSLMTNPVSINCGHSYCHLCITDFFKNPSQKQLRQETFCCPQCRAPF 66 Query: 65 SPADLRTNHTLNNLVEKLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQ 124 LR N L +L+E L + E + C H Q LFC ++ +L+C C+ Sbjct: 67 HMDSLRPNKQLGSLIEALKETDQEMS----------CEEHGEQFHLFCEDEGQLICWRCE 116 Query: 125 ADPRHQGHRVQPVKDTAHDFRAKCRNMEHALREKAKAFWAMRRSYEAIAKHNQVEAAWLE 184 P+H+GH V+D ++ K + L++ + S + + Sbjct: 117 RAPQHKGHTTALVEDVCQGYKEKLQKAVTKLKQLEDRCTEQKLSTAMRITKWKEKVQIQR 176 Query: 185 GRIRQEFDKLREFLRVEEQAILDAMAEETRQK-QLLADEKMKQLTEETEVLAHEIERLQM 243 +IR +F L+ FL EE++ L + +E +Q L D + + E+ +H +E L+ Sbjct: 177 QKIRSDFKNLQCFLHEEEKSYLWRLEKEEQQTLSRLRDYEAGLGLKSNELKSHILE-LEE 235 Query: 244 EMKEDDVSFLMKHKSRKRRLFCTMEPEPVQPGMLIDVCKYLGSLQYRVWKKMLASVESVP 303 + + L R + + + + L + V KKML S V Sbjct: 236 KCQGSAQKLLQNVNDTLSRSWAVKLETSEAVSLELHTMCNVSKLYFDV-KKMLRS-HQVS 293 Query: 304 FSFDPNTAAGWLSVSDDLTSVTNHGY--RVQVENPERFSSAPCLLGSRVFSQGSHAWEVA 361 + DP+TA L +S+D VT GY Q + RF++ PC+LG F+ G +EV Sbjct: 294 VTLDPDTAHHELILSEDRRQVT-RGYTQENQDTSSRRFTAFPCVLGCEGFTSGRRYFEVD 352 Query: 362 LGGLQSWRVGVVRVRQDSGAEGHSHSCYHDTRSGFW--YVCRTQGVEGDHCVTSDPATSP 419 +G W +GV G + +SGFW +C+ +G + + P TS Sbjct: 353 VGEGTGWDLGVCMENVQRGT-----GMKQEPQSGFWTLRLCKKKG----YVALTSPPTSL 403 Query: 420 LVLAIPRRLRVELECEEGELSFYDAERHCHLYTF-HARFGE-VRPYF 464 + P + + L+ E G +SFY+ CH++TF A F + +RPYF Sbjct: 404 HLHEQPLLVGIFLDYEAGVVSFYNGNTGCHIFTFPKASFSDTLRPYF 450 >gi|18079262 tripartite motif-containing 6 isoform 2 [Homo sapiens] Length = 488 Score = 139 bits (351), Expect = 4e-33 Identities = 125/473 (26%), Positives = 215/473 (45%), Gaps = 34/473 (7%) Query: 16 KEELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWEVQV-----SPTCPVCKDRASPADLR 70 +EE+ C +C + + +++ CGH+FC+ C++ V +CPVC+ P +LR Sbjct: 10 REEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQPGNLR 69 Query: 71 TNHTLNNLVEKLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQADPRHQ 130 N L N+V +L RE G + +C H +L LFC ED +++C C+ H+ Sbjct: 70 PNRHLANIVRRL-REVVLGPG--KQLKAVLCADHGEKLQLFCQEDGKVICWLCERSQEHR 126 Query: 131 GHRVQPVKDTAHDFRAKCRNMEHALR---EKAKAFWAMRRSYEAIAKHNQVEAAWLEGRI 187 GH V++ A +++ K + L+ ++A+ A R + K NQ+E RI Sbjct: 127 GHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWK-NQMEPE--RCRI 183 Query: 188 RQEFDKLREFLRVEEQAILDAMAEETRQKQLLADEKMKQLTEETEVLAHEIERLQMEMKE 247 + EF++LR L EQ L + +E ++ + +E L +T+ L I L+ + Sbjct: 184 QTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRCQG 243 Query: 248 DDVSFLMKHKS-RKRRLFCTMEPEPVQPGMLIDVCKYLGSLQYRVWKKMLASVES--VPF 304 + L +R F T+ P L + + + + L V+S V Sbjct: 244 STMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYWVDV 303 Query: 305 SFDPNTAAGWLSVSDDLTSVTNHGYRVQVENPERFSSAPCLLGSRVFSQGSHAWEVALGG 364 + +P+TA L ++ + V G +V + +LGS+ FS G H WEV + Sbjct: 304 TLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEKHYDCSVLGSQHFSSGKHYWEVDVAK 363 Query: 365 LQSWRVGVV------RVRQDSGAEGHSHSCYHDTRSGFWYVCRTQGVEGDHCVTSDPATS 418 +W +GV + A+ HS + +SG+W + G++ +H + +S Sbjct: 364 KTAWILGVCSNSLGPTFSFNHFAQNHSAYSRYQPQSGYWVI----GLQHNHEYRAYEDSS 419 Query: 419 PLVL----AIPRRLRVELECEEGELSFYDAERH-CHLYTFHARF--GEVRPYF 464 P +L PRR+ V L+ E G +SFY+ H +YTF + + PYF Sbjct: 420 PSLLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPYF 472 >gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens] Length = 516 Score = 139 bits (351), Expect = 4e-33 Identities = 125/473 (26%), Positives = 215/473 (45%), Gaps = 34/473 (7%) Query: 16 KEELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWEVQV-----SPTCPVCKDRASPADLR 70 +EE+ C +C + + +++ CGH+FC+ C++ V +CPVC+ P +LR Sbjct: 38 REEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQPGNLR 97 Query: 71 TNHTLNNLVEKLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQADPRHQ 130 N L N+V +L RE G + +C H +L LFC ED +++C C+ H+ Sbjct: 98 PNRHLANIVRRL-REVVLGPG--KQLKAVLCADHGEKLQLFCQEDGKVICWLCERSQEHR 154 Query: 131 GHRVQPVKDTAHDFRAKCRNMEHALR---EKAKAFWAMRRSYEAIAKHNQVEAAWLEGRI 187 GH V++ A +++ K + L+ ++A+ A R + K NQ+E RI Sbjct: 155 GHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWK-NQMEPE--RCRI 211 Query: 188 RQEFDKLREFLRVEEQAILDAMAEETRQKQLLADEKMKQLTEETEVLAHEIERLQMEMKE 247 + EF++LR L EQ L + +E ++ + +E L +T+ L I L+ + Sbjct: 212 QTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRCQG 271 Query: 248 DDVSFLMKHKS-RKRRLFCTMEPEPVQPGMLIDVCKYLGSLQYRVWKKMLASVES--VPF 304 + L +R F T+ P L + + + + L V+S V Sbjct: 272 STMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYWVDV 331 Query: 305 SFDPNTAAGWLSVSDDLTSVTNHGYRVQVENPERFSSAPCLLGSRVFSQGSHAWEVALGG 364 + +P+TA L ++ + V G +V + +LGS+ FS G H WEV + Sbjct: 332 TLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEKHYDCSVLGSQHFSSGKHYWEVDVAK 391 Query: 365 LQSWRVGVV------RVRQDSGAEGHSHSCYHDTRSGFWYVCRTQGVEGDHCVTSDPATS 418 +W +GV + A+ HS + +SG+W + G++ +H + +S Sbjct: 392 KTAWILGVCSNSLGPTFSFNHFAQNHSAYSRYQPQSGYWVI----GLQHNHEYRAYEDSS 447 Query: 419 PLVL----AIPRRLRVELECEEGELSFYDAERH-CHLYTFHARF--GEVRPYF 464 P +L PRR+ V L+ E G +SFY+ H +YTF + + PYF Sbjct: 448 PSLLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPYF 500 >gi|42516572 tripartite motif-containing 41 isoform 1 [Homo sapiens] Length = 630 Score = 137 bits (345), Expect = 2e-32 Identities = 124/461 (26%), Positives = 194/461 (42%), Gaps = 46/461 (9%) Query: 56 TCPVCKDRASPADLRTNHTLNNLVEKLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLED 115 TCP C+ R N L N+V+ + + R + +C H+ L LFC D Sbjct: 182 TCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGICPKHQEALKLFCEVD 241 Query: 116 KELLCCSCQADPRHQGHRVQPVKDTAHDFRAKCRNMEHALREKAKAFWAMRRSYEAIAKH 175 +E +C C+ H+ H V P+++ +++AK + LR+ +A M+ E Sbjct: 242 EEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMKAKEERRVTE 301 Query: 176 NQVEAAWLEGRIRQEFDKLREFLRVEEQAILDAMAEETRQKQL-LADEKMKQLTEETEVL 234 + + + EF +L FL EEQA L+ E + QL A +L E+ L Sbjct: 302 LKSQMKSELAAVASEFGRLTRFL-AEEQAGLERRLREMHEAQLGRAGAAASRLAEQAAQL 360 Query: 235 AHEIERLQMEMKEDDVSFLMKHKSRKRRLFC---------TMEPEPVQPGMLIDVCKYLG 285 + + Q ++ + L K R C P+P QP +L Sbjct: 361 SRLLAEAQERSQQGGLRLLQDIKETFNR--CEEVQLQPPEVWSPDPCQP----HSHDFLT 414 Query: 286 SLQYRVWKKMLASVESVPFSFDPNTAAGWLSVSDDLTSVTNHGYRVQV-ENPERFSSAPC 344 R +M V + DP+TA L +S D V R +V ++P+RFS+ C Sbjct: 415 DAIVRKMSRMFCQAARVDLTLDPDTAHPALMLSPDRRGVRLAERRQEVADHPKRFSADCC 474 Query: 345 LLGSRVFSQGSHAWEVALGGLQSWRVGVVRVRQ----------DSGAEGHSHSCYHDTRS 394 +LG++ F G H WEV +GG + W VG R S G + S H R Sbjct: 475 VLGAQGFRSGRHYWEVEVGGRRGWAVGAARESTHHKEKVGPGGSSVGSGDASSSRHHHRR 534 Query: 395 GFWYVCRTQGVEGD-HCV-------TSDPATSPLVLA---IPRRLRVELECEEGELSFYD 443 ++ + ++ + CV + +T +L+ PRR V L+ E G L FY+ Sbjct: 535 RRLHLPQQPLLQREVWCVGTNGKRYQAQSSTEQTLLSPSEKPRRFGVYLDYEAGRLGFYN 594 Query: 444 AERHCHLYTFHARF-GE-VRPYFYLGGARGAGPPEPLRICP 482 AE H++TF A F GE V P+F R +++CP Sbjct: 595 AETLAHVHTFSAAFLGERVFPFF-----RVLSKGTRIKLCP 630 Score = 58.5 bits (140), Expect = 1e-08 Identities = 21/43 (48%), Positives = 32/43 (74%) Query: 7 VSPGPSRSFKEELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCW 49 ++P P ++ +EE +CA+C D F D V++ CGHNFCR CV++ W Sbjct: 6 MTPNPVQTLQEEAVCAICLDYFTDPVSIGCGHNFCRVCVTQLW 48 >gi|14670266 tripartite motif protein TRIM4 isoform alpha [Homo sapiens] Length = 500 Score = 135 bits (340), Expect = 8e-32 Identities = 134/505 (26%), Positives = 195/505 (38%), Gaps = 72/505 (14%) Query: 12 SRSFKEELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWEVQVSP-TCPVCKDRASPADLR 70 + +EEL C +C D F+D V++ CGHNFCRGC+ R W P CP C+ ++PA LR Sbjct: 3 AEDIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSAPAALR 62 Query: 71 TNHTLNNLVEKLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQADPRHQ 130 N L L EK R +C H L LFC +D+ +C C+ HQ Sbjct: 63 PNWALARLTEKTQRRRLGPVP------PGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQ 116 Query: 131 GHRVQPVKDTAHDFRA----------KCRNMEHALREKAKAFWAMRRSYEAIAKHNQV-- 178 H + P+ + +R K R + L + ++ +AK +V Sbjct: 117 THAMAPIDEAFESYRTGNFDIHVDEWKRRLIRLLLYHSKQEEKLLKSQRNLVAKMKKVMH 176 Query: 179 --------EAAWLEG------RIRQEFDKLREFLRVEEQAILDAMAEETRQKQLLADEKM 224 W + RI EF KL FL EE L + +E +E Sbjct: 177 LQDVEVKNATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKE-------EEETK 229 Query: 225 KQLTEETEVLAHEI---ERLQMEMKEDDVSFLMKHKSRKRRLFCTMEPEPVQPGMLIDVC 281 K+L E T L I ++L +E+ E + ++ + + E + V ++ Sbjct: 230 KKLNENTLKLNQTIASLKKLILEVGEKSQAPTLELLQNPKEVLTRSEIQDV--NYSLEAV 287 Query: 282 KYLGSLQYRVWKKMLASVESVPFSFDPNTAAGWLSVSDDLTSVTN-------------HG 328 K Q + K+ML + V + +TA L S + V N Sbjct: 288 KVKTVCQIPLMKEMLKRFQ-VAVNLAEDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWN 346 Query: 329 YRVQVENP------ERFSSAPCLLGSRVFSQGSHAWEVALGGLQSWRVGVVRVRQDSGAE 382 Y NP ERF PC+LG VF+ G H WEV VGV R Sbjct: 347 YFAGWRNPQKTAFVERFQHLPCVLGKNVFTSGKHYWEVESRDSLEVAVGVCR----EDVM 402 Query: 383 GHSHSCYHDTRSGFWYVCRTQGVEGDHCVTSDPATSPLVLAIPRRLRVELECEEGELSFY 442 G + G W + G + P T R+ V L+ G +SFY Sbjct: 403 GITDRSKMSPDVGIWAI--YWSAAGYWPLIGFPGTPTQQEPALHRVGVYLDRGTGNVSFY 460 Query: 443 DAERHCHLYTFH-ARFGEVRPYFYL 466 A HL+TF + +RP+F+L Sbjct: 461 SAVDGVHLHTFSCSSVSRLRPFFWL 485 >gi|56605981 tripartite motif-containing 72 [Homo sapiens] Length = 477 Score = 135 bits (339), Expect = 1e-31 Identities = 128/473 (27%), Positives = 200/473 (42%), Gaps = 54/473 (11%) Query: 17 EELLCAVCYDPFRDAVTLRCGHNFCRGCVSR-CWEVQVSPT--CPVCKDRASPADLRTNH 73 +EL C +C F VT CGH+FCR C+ R E T CP C+ P L TN Sbjct: 10 QELSCPLCLQLFDAPVTAECGHSFCRACLGRVAGEPAADGTVLCPCCQAPTRPQALSTNL 69 Query: 74 TLNNLVEKLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQADPRHQGHR 133 L LVE L + +G C H LS++C +D+ L+C C + H+GHR Sbjct: 70 QLARLVEG-LAQVPQGH----------CEEHLDPLSIYCEQDRALVCGVCASLGSHRGHR 118 Query: 134 VQPVKDTAHDFRAKCRNMEHALREKAKAFWAMRRSYE-AIAKHNQVE----AAWLEGRIR 188 + P + + + + L+E MR+ A+ +H VE G + Sbjct: 119 LLPAAEAHARLKTQLPQQKLQLQEA-----CMRKEKSVAVLEHQLVEVEETVRQFRGAVG 173 Query: 189 QEFDKLREFLRVEEQAILDAMAEETRQKQLLA-DEKMKQLTEETEVLAHEIERLQMEMKE 247 ++ K+R FL E + LD AE R + +A ++ L E L + L+ + Sbjct: 174 EQLGKMRVFLAALEGS-LDCEAERVRGEAGVALRRELGSLNSYLEQLRQMEKVLEEVADK 232 Query: 248 DDVSFLMKHKSRKRRLFCTMEPEPVQPGMLIDVCKYLGSLQYRVWKKMLASVESV--PFS 305 FLMK+ RL + P + I + +++VW+KM ++ + Sbjct: 233 PQTEFLMKYCLVTSRLQKILAESPPPARLDIQLPIISDDFKFQVWRKMFRALMPALEELT 292 Query: 306 FDPNTAAGWLSVSDDLTSVTNHGYRVQV---------ENPERFSSAPCLLGSRVFSQGSH 356 FDP++A L VS + G RV+ E+P +F A ++ + S+G H Sbjct: 293 FDPSSAHPSLVVS-------SSGRRVECSEQKAPPAGEDPRQFDKAVAVVAHQQLSEGEH 345 Query: 357 AWEVALGGLQSWRVGVVRVRQDSGAEGHSHSCYHDTRSGFWYVCRTQG-VEGDHCVTSDP 415 WEV +G W +GV+ ++ G H+ G W + +G + H +P Sbjct: 346 YWEVDVGDKPRWALGVIAA--EAPRRGRLHAV---PSQGLWLLGLREGKILEAHVEAKEP 400 Query: 416 ATSPLVLAIPRRLRVELECEEGELSFY---DAERHCHLYTFHARFGE-VRPYF 464 P R+ + L +G LSFY DA+ L+ FH R V P+F Sbjct: 401 RALRSPERRPTRIGLYLSFGDGVLSFYDASDADALVPLFAFHERLPRPVYPFF 453 >gi|68160935 tripartite motif-containing 17 isoform 2 [Homo sapiens] Length = 450 Score = 134 bits (336), Expect = 2e-31 Identities = 121/468 (25%), Positives = 201/468 (42%), Gaps = 69/468 (14%) Query: 36 CGHNFCRGCVSRCWEV----------QVSPTCPVCKDRASPADLRTNHTLNNLVEKLLRE 85 CGHNFCR C+ WE + S CP C++ + +L N L + E + + Sbjct: 4 CGHNFCRACIQLSWEKARGKKGRRKRKGSFPCPECREMSPQRNLLPNRLLTKVAE--MAQ 61 Query: 86 EAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQADPRHQGHRVQPVKDTAHDFR 145 + G + +C+ H L LFC +D+ +C C+ H+ HRV P ++ ++ Sbjct: 62 QHPGLQKQD-----LCQEHHEPLKLFCQKDQSPICVVCRESREHRLHRVLPAEEAVQGYK 116 Query: 146 AKCRNMEHALREKAKAFWAMRRSYEAIAKHNQVEAAWLEGRIRQ-------EFDKLREFL 198 K LRE+ + R+ A+ Q A W +G++++ EF+K+ +L Sbjct: 117 LKLEEDMEYLREQ------ITRTGNLQAREEQSLAEW-QGKVKERRERIVLEFEKMNLYL 169 Query: 199 RVEEQAILDAMAEETRQKQLLADEKMKQLTEETEVLAHEIERLQMEMKEDDVSFL----- 253 EEQ +L A+ E + E + L + H +E L ++++E Sbjct: 170 VEEEQRLLQALETEEEETASRLRESVACLDRQ----GHSLELLLLQLEERSTQGPLQMLQ 225 Query: 254 -MKHKSRKRRLFCTMEPEPVQPGMLIDVCKYLGSLQYRVWKKMLASVESVPFSFDPNTAA 312 MK ++ PE P VC+ G Q V + L V VP D +A Sbjct: 226 DMKEPLSRKNNVSVQCPEVAPPTRPRTVCRVPG--QIEVLRGFLEDV--VP---DATSAY 278 Query: 313 GWLSVSDDL------TSVTNHGYRVQVENPERFSSAPCLLGSRVFSQGSHAWEVALG--G 364 +L + + +S G+ + +RF + PC +G FS G H WEV + G Sbjct: 279 PYLLLYESRQRRYLGSSPEGSGFC----SKDRFVAYPCAVGQTAFSSGRHYWEVGMNITG 334 Query: 365 LQSWRVGVVRVRQDSGAEGHSHSCYHDTRSGFWYVCRTQGVEGDHCVTSDPATSPLVLAI 424 W +GV R + + C +GFW V ++G + + T T +++ Sbjct: 335 DALWALGV--CRDNVSRKDRVPKC---PENGFWVVQLSKGTK--YLSTFSALTPVMLMEP 387 Query: 425 PRRLRVELECEEGELSFYDAERHCHLYTF-HARF-GEVRPYFYLGGAR 470 P + + L+ E GE+SFY HL+T+ A F G ++P+F LG + Sbjct: 388 PSHMGIFLDFEAGEVSFYSVSDGSHLHTYSQATFPGPLQPFFCLGAPK 435 >gi|31542779 tripartite motif family-like 1 [Homo sapiens] Length = 468 Score = 131 bits (330), Expect = 1e-30 Identities = 122/481 (25%), Positives = 203/481 (42%), Gaps = 28/481 (5%) Query: 14 SFKEELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWEVQVSP-TCPVCKDRASPADLRTN 72 + +EEL C +C D F VT CGH+FC C+ R WE +P +CP C ++N Sbjct: 9 NLREELTCFICLDYFSSPVTTECGHSFCLVCLLRSWEEHNTPLSCPECWRTLEGPHFQSN 68 Query: 73 HTLNNL--VEKLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQADPRHQ 130 L L + + LR + + + R+ + L D E + A H Sbjct: 69 ERLGRLASIARQLRSQVLQSEDEQGSYGRM------PTTAKALSDDEQGGSAFVAQ-SHG 121 Query: 131 GHRVQPVKDTAHDFRAKCRNMEHALREKAKAFWAMRRSYEAIAKHNQVEAAWLEGRIRQE 190 +RV + R K + + + LR + K A+ + K Q E + + E Sbjct: 122 ANRVHLSSEAEEHHREKLQEILNLLRVRRKEAQAVLTHEKERVKLCQEETKTCKQVVVSE 181 Query: 191 FDKLREFLRVEEQAILDAMAEETRQKQLLADEKMKQLTEETEVLAHEIERLQMEMKEDDV 250 + K+ +FL+ EEQ L + +E ++ +LT++ L+ I +++ + Sbjct: 182 YMKMHQFLKEEEQLQLQLLEQEEKENMRKLRNNEIKLTQQIRSLSKMIAQIESSSQSSAF 241 Query: 251 SFLMKHKSRKRRLFCTMEPEPVQPGMLIDVCKYLGSLQYRVWKKMLASVESVPFSFDPNT 310 L + + R + P + +C+ G K+ML S + DP T Sbjct: 242 ESLEEVRGALERSEPLLLQCPEATTTELSLCRITG------MKEMLRKF-STEITLDPAT 294 Query: 311 AAGWLSVSDDLTSVTNHGYRVQV-ENPERFSSAPCLLGSRVFSQGSHAWEVALGGLQSWR 369 A +L +S+DL SV G R Q+ +NPERF + +LG+++F+ G H WEV +G W Sbjct: 295 ANAYLVLSEDLKSVKYGGSRQQLPDNPERFDQSATVLGTQIFTSGRHYWEVEVGNKTEWE 354 Query: 370 VGVVRVRQDSGAEGHSHSCYHDTRSGFWYVCRTQGVEGDHCV-TSDPATSPLVLAIPRRL 428 VG+ + + S G + + D+ + S P V ++ Sbjct: 355 VGICK-------DSVSRKGNLPKPPGDLFSLIGLKIGDDYSLWVSSPLKGQHVREPVCKV 407 Query: 429 RVELECEEGELSFYDAERHCHLYTF-HARFGE-VRPYFYLGGARGAGPPEPLRICPLHIS 486 V L+ E G ++FY+ +Y+F A F E +RP F +PL IC L+ Sbjct: 408 GVFLDYESGHIAFYNGTDESLIYSFPQASFQEALRPIFSPCLPNEGTNTDPLTICSLNSH 467 Query: 487 V 487 V Sbjct: 468 V 468 >gi|20270353 tripartite motif-containing 43 [Homo sapiens] Length = 446 Score = 129 bits (325), Expect = 5e-30 Identities = 125/482 (25%), Positives = 207/482 (42%), Gaps = 69/482 (14%) Query: 12 SRSFKEELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWEVQVSP-TCPVCKDRASPADLR 70 S +F++EL C +C + D VT+ CGH+FCR C+ WE SP CP C++ + D + Sbjct: 6 SHAFQKELTCVICLNYLVDPVTICCGHSFCRPCLCLSWEEAQSPANCPACREPSPKMDFK 65 Query: 71 TNHTLNNLVEKLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQADPRHQ 130 TN L NLV + +A ++ S ++C HR +FC DK LLC C H Sbjct: 66 TNILLKNLV--TIARKASLWQFLSSE-KQICGTHRQTKKMFCDMDKSLLCLLCSNSQEHG 122 Query: 131 GHRVQPVKDTAHDFRAKCRNMEHALREKAKAFWAMRRSYEA-----IAKHNQVEAAWLEG 185 H+ P+++ A + R K L +K + R YE + + N V A + Sbjct: 123 AHKHHPIEEAAEEHREKLLKQMRILWKKIQE--NQRNLYEEGRTAFLWRGNVVLRAQM-- 178 Query: 186 RIRQEFDKLREFLRVEEQAILDAMAEE-------TRQKQLLADEKMKQLTEETEVLAHEI 238 IR E+ KL L EE+ L+ + +E ++ + D+K K L E + L Sbjct: 179 -IRNEYRKLHPVLHKEEKQHLERLNKEYQEIFQQLQRSWVKMDQKSKHLKEMYQELMEMC 237 Query: 239 ERLQMEMKEDDVSFLMKHKSRKRRLFCTMEPEPVQPGMLIDVCKYLGSLQYRVWKKMLAS 298 + +E+ +D + + +S + P+PV P + G + V++ Sbjct: 238 HKPDVELLQDLGDIVARSESVLLHM-----PQPVNPELT------AGPITGLVYRLNRFR 286 Query: 299 VESVPFSFDPNTAAGWLSVSDDLTSVTNHGYRVQVE-----------NPERFSSAPCLLG 347 VE + F F+ VTNH R+ + N +R S G Sbjct: 287 VE-ISFHFE----------------VTNHNIRLFEDVRSWMFRRGPLNSDR-SDYFAAWG 328 Query: 348 SRVFSQGSHAWEVALGGLQSWRVGVVRVRQDSGAEGHSHSCYHDTRSGFWYVCRTQGVEG 407 +RVFS G H WE+ + W +GV + + +S ++ F +C + Sbjct: 329 ARVFSFGKHYWELDVDNSCDWALGVC-----NNSWIRKNSTMVNSEDIFLLLC-LKVDNH 382 Query: 408 DHCVTSDPATSPLVLAIPRRLRVELECEEGELSFYDAERHCHLYTFHA--RFGEVRPYFY 465 + +T+ P + R+ V L+ E G +SF + + ++++ A VRP+FY Sbjct: 383 FNLLTTSPVFPHYIEKPLGRVGVFLDFESGSVSFLNVTKSSLIWSYPAGSLTFPVRPFFY 442 Query: 466 LG 467 G Sbjct: 443 TG 444 >gi|88953346 PREDICTED: Tripartite motif-containing protein 43-like protein 1 [Homo sapiens] Length = 446 Score = 129 bits (323), Expect = 8e-30 Identities = 122/481 (25%), Positives = 208/481 (43%), Gaps = 67/481 (13%) Query: 12 SRSFKEELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWEVQVSP-TCPVCKDRASPADLR 70 S +F++EL C +C + D VT+ CGH+FCR C+ WE SP CP C++ + D + Sbjct: 6 SHAFQKELTCVICLNYLVDPVTICCGHSFCRPCLCLSWEEAQSPANCPACREPSPKMDFK 65 Query: 71 TNHTLNNLVEKLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQADPRHQ 130 TN L NLV + +A ++ S ++C HR +FC DK LLC C H Sbjct: 66 TNILLKNLV--TIARKASLWQFLSSE-KQICGTHRQTKKMFCDMDKSLLCLLCSNSQEHG 122 Query: 131 GHRVQPVKDTAHDFRAK----CRNMEHALREKAKAFWAMRRSYEAIAKHNQVEAAWLEGR 186 H+ P+++ A + R K R + ++E + + RR+ + + A Sbjct: 123 AHKHYPIEEAAEEDREKLLKQMRILWKKIQENQRNLYEERRTAFLLRGDVVLRAQ----M 178 Query: 187 IRQEFDKLREFLRVEEQAILDAMAEE-------TRQKQLLADEKMKQLTEETEVLAHEIE 239 IR E+ KL L EE+ L+ + +E ++ + D+K K L E + L Sbjct: 179 IRNEYRKLHPVLHKEEKQHLERLNKEYQEIFQQLQRSWVKMDQKSKHLKEMYQELMEMCH 238 Query: 240 RLQMEMKEDDVSFLMKHKSRKRRLFCTMEPEPVQPGMLIDVCKYLGSLQYRVWKKMLASV 299 + ++E+ +D + + +S + P+PV P + G + V++ V Sbjct: 239 KPEVELLQDLGDIVARSESVLLHM-----PQPVNPELT------AGPITGLVYRLNRFRV 287 Query: 300 ESVPFSFDPNTAAGWLSVSDDLTSVTNHGYRVQVE-----------NPERFSSAPCLLGS 348 E + F F+ VTNH R+ + N +R S G+ Sbjct: 288 E-ISFHFE----------------VTNHNIRLFEDVRSWMFRRGPLNSDR-SDYFAAWGA 329 Query: 349 RVFSQGSHAWEVALGGLQSWRVGVVRVRQDSGAEGHSHSCYHDTRSGFWYVCRTQGVEGD 408 RVFS G H WE+ + W +GV + + +S ++ F +C + Sbjct: 330 RVFSFGKHYWELDVDNSCDWALGVC-----NNSWIRKNSTMVNSEDIFLLLC-LKVDNHF 383 Query: 409 HCVTSDPATSPLVLAIPRRLRVELECEEGELSFYDAERHCHLYTFHA--RFGEVRPYFYL 466 + +T+ P + R+ V L+ E G +SF + + ++++ A VRP+FY Sbjct: 384 NLLTTSPVFPHYIEKPLGRVGVFLDFESGSVSFLNVTKSSLIWSYPAGSLTFPVRPFFYT 443 Query: 467 G 467 G Sbjct: 444 G 444 >gi|157426896 tripartite motif-containing 10 isoform 2 [Homo sapiens] Length = 395 Score = 127 bits (320), Expect = 2e-29 Identities = 107/394 (27%), Positives = 174/394 (44%), Gaps = 51/394 (12%) Query: 14 SFKEELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWEV-----QVSPTCPVCKDRASPAD 68 S +E+ C +C R+ VT+ CGHNFCR C++R E+ + SPTCP+CK+ P Sbjct: 9 SLADEVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLCKEPFRPGS 68 Query: 69 LRTNHTLNNLVEKLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQADPR 128 R N L N+VE + E + VC+ H ++ FC +D+ LC C+ Sbjct: 69 FRPNWQLANVVENI--ERLQLVSTLGLGEEDVCQEHGEKIYFFCEDDEMQLCVVCREAGE 126 Query: 129 HQGHRVQPVKDTAHDFRAKCRNMEHALREKAKAFWAMRRSYEAIAKHNQVEAAWLEGRIR 188 H H ++ ++D A +R + LR++ + ++ + + + ++ Sbjct: 127 HATHTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQSRENKRMQVLLTQVSTKRQQVI 186 Query: 189 QEFDKLREFLRVEEQAILDAMAEE-----TRQK---QLLADEKMKQLTEETEVLAHEIER 240 EF LR+FL E+Q+IL A E RQ+ LL ++ + + E L + ER Sbjct: 187 SEFAHLRKFLE-EQQSILLAQLESQDGDILRQRDEFDLLVAGEICRFSALIEELEEKNER 245 Query: 241 LQMEMKEDDVSFLMKHKSRKRRLFCTMEPE-------------PVQPGMLIDVCKYLGSL 287 E+ D S L++ ++RK R + PE P+Q M + + K L Sbjct: 246 PARELLTDIRSTLIRCETRKCRKPVAVSPELGQRIRDFPQQALPLQREMKMFLEKLCFEL 305 Query: 288 QYRVWKKMLASVESVPFSFDPNTAAGWLSVSDD-LTSVTNHGYRVQVENPERFSSAPCLL 346 Y E S DP T+ L +S+D + ++ ++ +NP+RF A C+L Sbjct: 306 DY----------EPAHISLDPQTSHPKLLLSEDHQRAQFSYKWQNSPDNPQRFDRATCVL 355 Query: 347 GSRVFSQGSHAWEVALGGLQSWRVGVVRVRQDSG 380 + G H W V + RV DSG Sbjct: 356 AHTGITGGRHTW-----------VWMARVPGDSG 378 >gi|117938316 tripartite motif-containing 22 [Homo sapiens] Length = 498 Score = 127 bits (318), Expect = 3e-29 Identities = 135/512 (26%), Positives = 218/512 (42%), Gaps = 102/512 (19%) Query: 16 KEELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWEVQV-----SPTCPVCKDRASPADLR 70 ++E+ C +C + + ++L CGH+FC+ C++ + V +CPVC+ R P +LR Sbjct: 10 EKEVTCPICLELLTEPLSLDCGHSFCQACITAKIKESVIISRGESSCPVCQTRFQPGNLR 69 Query: 71 TNHTLNNLVEKLLREEA---EGARWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQADP 127 N L N+VE++ + EG + VC H +L +FC ED +++C C+ Sbjct: 70 PNRHLANIVERVKEVKMSPQEGQK------RDVCEHHGKKLQIFCKEDGKVICWVCELSQ 123 Query: 128 RHQGHRVQPVKDTAHDFRAKCRNMEHALREKAKAFWAMRRSYEAIAKHNQVEAAWLEGRI 187 HQGH+ + + + + K ++ + + + K +Q EA LE I Sbjct: 124 EHQGHQTFRINEVVKECQEK-----------------LQVALQRLIKEDQ-EAEKLEDDI 165 Query: 188 RQEFDKLREFLRVEEQAILDAM--------AEETRQKQLL-------------ADEKMKQ 226 RQE + ++++E Q IL EE R+ Q L A +++ Q Sbjct: 166 RQERTAWKNYIQIERQKILKGFNEMRVILDNEEQRELQKLEEGEVNVLDNLAAATDQLVQ 225 Query: 227 LTEETEVLAHEIER----LQMEMKEDDVSF--------LMKHKSRKRRLFCTMEPEPVQP 274 ++ L +++R +EM +D + L K KS ++L P Sbjct: 226 QRQDASTLISDLQRRLRGSSVEMLQDVIDVMKRSESWTLKKPKSVSKKLKSVFR-VPDLS 284 Query: 275 GMLIDVCKYLGSLQYRVWKKMLASVESVPFSFDPNTAAGWLSVSDDLTSV-TNHGYRVQV 333 GML V K L +QY W V +P +A +++S D V T + Sbjct: 285 GML-QVLKELTDVQY-YW---------VDVMLNPGSATSNVAISVDQRQVKTVRTCTFKN 333 Query: 334 ENPERFSSAPCLLGSRVFSQGSHAWEVALGGLQSWRVGV------VRVRQDSGAEGHSHS 387 NP F SA + G + FS G + WEV + G +W +GV + R+ SG Sbjct: 334 SNPCDF-SAFGVFGCQYFSSGKYYWEVDVSGKIAWILGVHSKISSLNKRKSSGFAFDPSV 392 Query: 388 CYHDTRS------GFWYV-----CRTQGVEGDHCVTSDPATSPLVLAIPR-RLRVELECE 435 Y S G+W + C E +SDP L +A+P R+ V L+ E Sbjct: 393 NYSKVYSRYRPQYGYWVIGLQNTCEYNAFEDSS--SSDPKVLTLFMAVPPCRIGVFLDYE 450 Query: 436 EGELSFYDAERH-CHLYTFH-ARFGE-VRPYF 464 G +SF++ H +Y F RF PYF Sbjct: 451 AGIVSFFNVTNHGALIYKFSGCRFSRPAYPYF 482 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.322 0.135 0.431 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 21,109,279 Number of Sequences: 37866 Number of extensions: 982991 Number of successful extensions: 4656 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 239 Number of HSP's successfully gapped in prelim test: 337 Number of HSP's that attempted gapping in prelim test: 3503 Number of HSP's gapped (non-prelim): 1075 length of query: 493 length of database: 18,247,518 effective HSP length: 106 effective length of query: 387 effective length of database: 14,233,722 effective search space: 5508450414 effective search space used: 5508450414 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.