Search of human proteins with 94536782

Search of human proteins with 94536782

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|94536782 tripartite motif-containing 35 isoform 2 [Homo
sapiens]
         (493 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|94536782 tripartite motif-containing 35 isoform 2 [Homo sapiens]  1030   0.0  
gi|21630277 tripartite motif-containing 11 [Homo sapiens]             197   1e-50
gi|15208660 tripartite motif protein 21 [Homo sapiens]                183   4e-46
gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens]   181   1e-45
gi|22749269 ring finger protein 129 [Homo sapiens]                    178   1e-44
gi|157743261 tripartite motif-containing 75 [Homo sapiens]            178   1e-44
gi|5730009 ret finger protein [Homo sapiens]                          177   3e-44
gi|217035095 tripartite motif-containing 62 [Homo sapiens]            176   6e-44
gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens]   174   1e-43
gi|112421127 tripartite motif-containing 58 [Homo sapiens]            172   6e-43
gi|88999601 tripartite motif-containing 69 isoform a [Homo sapiens]   166   3e-41
gi|44680122 tripartite motif-containing 7 isoform 1 [Homo sapiens]    166   6e-41
gi|37622899 ring finger protein 137 [Homo sapiens]                    164   1e-40
gi|30023818 tripartite motif protein 50A [Homo sapiens]               159   7e-39
gi|68160933 tripartite motif-containing 17 isoform 1 [Homo sapiens]   153   4e-37
gi|7705825 tripartite motif-containing 17 isoform 1 [Homo sapiens]    153   4e-37
gi|15011941 tripartite motif protein TRIM4 isoform beta [Homo sa...   145   1e-34
gi|157426898 tripartite motif-containing 10 isoform 1 [Homo sapi...   144   1e-34
gi|5454014 tripartite motif-containing 38 [Homo sapiens]              141   2e-33
gi|18079262 tripartite motif-containing 6 isoform 2 [Homo sapiens]    139   4e-33
gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens]    139   4e-33
gi|42516572 tripartite motif-containing 41 isoform 1 [Homo sapiens]   137   2e-32
gi|14670266 tripartite motif protein TRIM4 isoform alpha [Homo s...   135   8e-32
gi|56605981 tripartite motif-containing 72 [Homo sapiens]             135   1e-31
gi|68160935 tripartite motif-containing 17 isoform 2 [Homo sapiens]   134   2e-31
gi|31542779 tripartite motif family-like 1 [Homo sapiens]             131   1e-30
gi|20270353 tripartite motif-containing 43 [Homo sapiens]             129   5e-30
gi|88953346 PREDICTED: Tripartite motif-containing protein 43-li...   129   8e-30
gi|157426896 tripartite motif-containing 10 isoform 2 [Homo sapi...   127   2e-29
gi|117938316 tripartite motif-containing 22 [Homo sapiens]            127   3e-29

>gi|94536782 tripartite motif-containing 35 isoform 2 [Homo sapiens]
          Length = 493

 Score = 1030 bits (2663), Expect = 0.0
 Identities = 493/493 (100%), Positives = 493/493 (100%)

Query: 1   MERSPDVSPGPSRSFKEELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWEVQVSPTCPVC 60
           MERSPDVSPGPSRSFKEELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWEVQVSPTCPVC
Sbjct: 1   MERSPDVSPGPSRSFKEELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWEVQVSPTCPVC 60

Query: 61  KDRASPADLRTNHTLNNLVEKLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLC 120
           KDRASPADLRTNHTLNNLVEKLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLC
Sbjct: 61  KDRASPADLRTNHTLNNLVEKLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLC 120

Query: 121 CSCQADPRHQGHRVQPVKDTAHDFRAKCRNMEHALREKAKAFWAMRRSYEAIAKHNQVEA 180
           CSCQADPRHQGHRVQPVKDTAHDFRAKCRNMEHALREKAKAFWAMRRSYEAIAKHNQVEA
Sbjct: 121 CSCQADPRHQGHRVQPVKDTAHDFRAKCRNMEHALREKAKAFWAMRRSYEAIAKHNQVEA 180

Query: 181 AWLEGRIRQEFDKLREFLRVEEQAILDAMAEETRQKQLLADEKMKQLTEETEVLAHEIER 240
           AWLEGRIRQEFDKLREFLRVEEQAILDAMAEETRQKQLLADEKMKQLTEETEVLAHEIER
Sbjct: 181 AWLEGRIRQEFDKLREFLRVEEQAILDAMAEETRQKQLLADEKMKQLTEETEVLAHEIER 240

Query: 241 LQMEMKEDDVSFLMKHKSRKRRLFCTMEPEPVQPGMLIDVCKYLGSLQYRVWKKMLASVE 300
           LQMEMKEDDVSFLMKHKSRKRRLFCTMEPEPVQPGMLIDVCKYLGSLQYRVWKKMLASVE
Sbjct: 241 LQMEMKEDDVSFLMKHKSRKRRLFCTMEPEPVQPGMLIDVCKYLGSLQYRVWKKMLASVE 300

Query: 301 SVPFSFDPNTAAGWLSVSDDLTSVTNHGYRVQVENPERFSSAPCLLGSRVFSQGSHAWEV 360
           SVPFSFDPNTAAGWLSVSDDLTSVTNHGYRVQVENPERFSSAPCLLGSRVFSQGSHAWEV
Sbjct: 301 SVPFSFDPNTAAGWLSVSDDLTSVTNHGYRVQVENPERFSSAPCLLGSRVFSQGSHAWEV 360

Query: 361 ALGGLQSWRVGVVRVRQDSGAEGHSHSCYHDTRSGFWYVCRTQGVEGDHCVTSDPATSPL 420
           ALGGLQSWRVGVVRVRQDSGAEGHSHSCYHDTRSGFWYVCRTQGVEGDHCVTSDPATSPL
Sbjct: 361 ALGGLQSWRVGVVRVRQDSGAEGHSHSCYHDTRSGFWYVCRTQGVEGDHCVTSDPATSPL 420

Query: 421 VLAIPRRLRVELECEEGELSFYDAERHCHLYTFHARFGEVRPYFYLGGARGAGPPEPLRI 480
           VLAIPRRLRVELECEEGELSFYDAERHCHLYTFHARFGEVRPYFYLGGARGAGPPEPLRI
Sbjct: 421 VLAIPRRLRVELECEEGELSFYDAERHCHLYTFHARFGEVRPYFYLGGARGAGPPEPLRI 480

Query: 481 CPLHISVKEELDG 493
           CPLHISVKEELDG
Sbjct: 481 CPLHISVKEELDG 493


>gi|21630277 tripartite motif-containing 11 [Homo sapiens]
          Length = 468

 Score =  197 bits (502), Expect = 1e-50
 Identities = 149/481 (30%), Positives = 224/481 (46%), Gaps = 35/481 (7%)

Query: 8   SPGPSRSFKEELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWEVQVSP-TCPVCKDRASP 66
           +P  S + +EE  CA+C D F D V   CGHNFCR C+ RCW     P  CP C++ +  
Sbjct: 3   APDLSTNLQEEATCAICLDYFTDPVMTDCGHNFCRECIRRCWGQPEGPYACPECRELSPQ 62

Query: 67  ADLRTNHTLNNLVEKLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQAD 126
            +LR N  L  + E   R         S     VC  HR  L+ FC ++  LLC +C+  
Sbjct: 63  RNLRPNRPLAKMAEMARRLHP-----PSPVPQGVCPAHREPLAAFCGDELRLLCAACERS 117

Query: 127 PRHQGHRVQPVKDTAHDFRAKC-RNMEHALREKAKAFWAMRRSYE-AIAKHNQVEAAWLE 184
             H  HRV+P++D A D +AK  +++EH  ++   A     ++ E  +     VE+    
Sbjct: 118 GEHWAHRVRPLQDAAEDLKAKLEKSLEHLRKQMQDALLFQAQADETCVLWQKMVESQ--R 175

Query: 185 GRIRQEFDKLREFLRVEEQAILDAMAEETRQKQLLADEKMKQLTEETEVLAHEIERLQME 244
             +  EF++LR  L  EEQ +L  + EE  +      E    L +++  LA  I  L+  
Sbjct: 176 QNVLGEFERLRRLLAEEEQQLLQRLEEEELEVLPRLREGAAHLGQQSAHLAELIAELEGR 235

Query: 245 MKEDDVSFLMKHKSRKRRL-FCTMEPEPVQPGMLIDVCKYLGSLQYRVWKKMLASVESVP 303
            +   +  L   K   RR+    ++P  V P  L  VC+  G ++    ++    V    
Sbjct: 236 CQLPALGLLQDIKDALRRVQDVKLQPPEVVPMELRTVCRVPGLVE--TLRRFRGDV---- 289

Query: 304 FSFDPNTAAGWLSVSDDLTSVTNHGYRVQV-ENPERFSSAPCLLGSRVFSQGSHAWEVAL 362
            + DP+TA   L +S+D  SV     R  + ++PERF   PC+LG   F+ G H WEV +
Sbjct: 290 -TLDPDTANPELILSEDRRSVQRGDLRQALPDSPERFDPGPCVLGQERFTSGRHYWEVEV 348

Query: 363 GGLQSWRVGVVRVRQDSGAEGHSHSCYHDTRSGFWYVCRTQGVEGDHCVTSDPATSPLVL 422
           G   SW +GV R   +   +G          +GFW +       G +  +S+ A +PL  
Sbjct: 349 GDRTSWALGVCRENVNRKEKGEL-----SAGNGFWILV----FLGSYYNSSERALAPL-R 398

Query: 423 AIPRRLRVELECEEGELSFYDAERHCHLYTFH--ARFGEVRPYFYLGGARGAGPPEPLRI 480
             PRR+ + L+ E G LSFY A     L+ F      G +RP F    +  +  P P+ I
Sbjct: 399 DPPRRVGIFLDYEAGHLSFYSATDGSLLFIFPEIPFSGTLRPLF----SPLSSSPTPMTI 454

Query: 481 C 481
           C
Sbjct: 455 C 455


>gi|15208660 tripartite motif protein 21 [Homo sapiens]
          Length = 475

 Score =  183 bits (464), Expect = 4e-46
 Identities = 148/496 (29%), Positives = 236/496 (47%), Gaps = 53/496 (10%)

Query: 17  EELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWEVQVSPTCPVCKDRASPADLRTNHTLN 76
           EE+ C +C DPF + V++ CGH+FC+ C+S+  +   S  CPVC+ R    +LR N  L 
Sbjct: 12  EEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGS-VCPVCRQRFLLKNLRPNRQLA 70

Query: 77  NLVEKLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQADPRHQGHRVQP 136
           N+V  L     E    T       C +H  +L LFC +D + LC  C    +H+ H + P
Sbjct: 71  NMVNNLKEISQEAREGTQ---GERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAMVP 127

Query: 137 VKDTAHDFRAKCR------NMEHALREKAKAFWAMRRSYEAIAKHNQVEAAWLEGRIRQE 190
           +++ A +++ K +        +  L EK +   A++R+        Q      + RI  E
Sbjct: 128 LEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQ------KSRIHAE 181

Query: 191 FDKLREFLRVEEQAILDAMAEETRQKQLLADEKMKQLTEETEVLAHEIERLQ-------M 243
           F + + FL  EEQ  L  + ++ R++  +  EK  +L ++++ L   I  L        +
Sbjct: 182 FVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSAL 241

Query: 244 EMKEDDVSFLMKHKSRKRRLFCTMEPEPVQPGMLIDVCKYLGSLQYRVWKKMLASVESVP 303
           E+ ++ +  L + +S   +      PE      L  VC   G       KKML +  +V 
Sbjct: 242 ELLQEVIIVLERSESWNLKDLDITSPE------LRSVCHVPG------LKKMLRTC-AVH 288

Query: 304 FSFDPNTAAGWLSVSDDLTSVTNHGYRVQVE-NPERFSSAPCLLGSRVFSQGSHAWEVAL 362
            + DP+TA  WL +S+D   V     +  +  N ERF S P +LG++ F  G H WEV +
Sbjct: 289 ITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDV 348

Query: 363 GGLQSWRVGVVRVRQDSGAEGHSHSCYHDTRSGFW--YVCRTQGVEGDHCVTSDPATSPL 420
            G ++W +GV   R     +GH       ++SGFW  ++   Q  E      + P T PL
Sbjct: 349 TGKEAWDLGV--CRDSVRRKGH---FLLSSKSGFWTIWLWNKQKYEAG----TYPQT-PL 398

Query: 421 VLAIPR-RLRVELECEEGELSFYDAERHCHL-YTFH--ARFGEVRPYFYLGGARGAGPPE 476
            L +P  ++ + L+ E G +SFY+   H  L Y+F   A  G +RP+F  G   G     
Sbjct: 399 HLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFFSPGFNDGGKNTA 458

Query: 477 PLRICPLHISVKEELD 492
           PL +CPL+I  +   D
Sbjct: 459 PLTLCPLNIGSQGSTD 474


>gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens]
          Length = 488

 Score =  181 bits (459), Expect = 1e-45
 Identities = 140/473 (29%), Positives = 215/473 (45%), Gaps = 23/473 (4%)

Query: 18  ELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWE-VQVSPTCPVCKDRASPADLRTNHTLN 76
           E  C+VC +  ++ V + CGHNFC+ C++R WE ++    CPVC+  +    LR N  L 
Sbjct: 26  EASCSVCLEYLKEPVIIECGHNFCKACITRWWEDLERDFPCPVCRKTSRYRSLRPNRQLG 85

Query: 77  NLVEKLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQADPRHQGHRVQP 136
           ++VE   + +A   +    R   +C  H   LSLFC ED+E +C  C     H+ H V P
Sbjct: 86  SMVEIAKQLQAVKRK---IRDESLCPQHHEALSLFCYEDQEAVCLICAISHTHRAHTVVP 142

Query: 137 VKDTAHDFRAKCRNMEHALREKAKAFWAMRRSYEAIAKHNQVEAAWLEGRIRQEFDKLRE 196
           + D   +++ K +     L +K +     + S E      +        +I +EF++L  
Sbjct: 143 LDDATQEYKEKLQKCLEPLEQKLQEITRCKSSEEKKPGELKRLVESRRQQILREFEELHR 202

Query: 197 FLRVEEQAILDAMAEETRQKQLLADEKMKQLTEETEVLAHEIERLQMEMKEDDVSFLMKH 256
            L  E+Q +L  + EE +       E    L ++   LAH    ++ +  +     L   
Sbjct: 203 RLDEEQQVLLSRLEEEEQDILQRLRENAAHLGDKRRDLAHLAAEVEGKCLQSGFEMLKDV 262

Query: 257 KS--RKRRLFCTMEPEPVQPGMLIDVCKYLGSL--QYRVWKKMLASVESVPFSFDPNTAA 312
           KS   K     TME   V     I++ K   +   QY   +K+L  +     + DP TA 
Sbjct: 263 KSTLEKCEKVKTMEVTSVS----IELEKNFSNFPRQYFALRKILKQL-IADVTLDPETAH 317

Query: 313 GWLSVSDDLTSVTNHGYRVQ--VENPERFSSAPCLLGSRVFSQGSHAWEVALGGLQSWRV 370
             L +S+D  SV     R++   + P RF+  PC+L +  F+ G H WEV +G    W V
Sbjct: 318 PNLVLSEDRKSVKFVETRLRDLPDTPRRFTFYPCVLATEGFTSGRHYWEVEVGDKTHWAV 377

Query: 371 GVVRVRQDSGAEGHSHSCYHDTRSGFWYVCRTQGVEGDHCVTSDPATSPLVLAIPRRLRV 430
           GV R   DS +     +   +T  G+W V    G    +  T+ P T   +   P+R+ +
Sbjct: 378 GVCR---DSVSRKGELTPLPET--GYWRVRLWNG--DKYAATTTPFTPLHIKVKPKRVGI 430

Query: 431 ELECEEGELSFYDAERHCHLYTFHARFGE-VRPYFYLGGARGAGPPEPLRICP 482
            L+ E G LSFY+     H+YTF   F E + P FY G   G     PL I P
Sbjct: 431 FLDYEAGTLSFYNVTDRSHIYTFTDTFTEKLWPLFYPGIRAGRKNAAPLTIRP 483


>gi|22749269 ring finger protein 129 [Homo sapiens]
          Length = 471

 Score =  178 bits (451), Expect = 1e-44
 Identities = 141/482 (29%), Positives = 225/482 (46%), Gaps = 40/482 (8%)

Query: 14  SFKEELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCW-EVQVSPTCPVCKDRASPADLRTN 72
           + +EE  C +C +  +D VT+ CGHNFCR C+S  W ++  +  CPVC+        R N
Sbjct: 9   NLQEESSCPICLEYLKDPVTINCGHNFCRSCLSVSWKDLDDTFPCPVCRFCFPYKSFRRN 68

Query: 73  HTLNNLVEKLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQADPRHQGH 132
             L NL E   + +   ++    + + +C  H   L+LFC++D E+LC  C    +HQ H
Sbjct: 69  PQLRNLTEIAKQLQIRRSKRKRQKENAMCEKHNQFLTLFCVKDLEILCTQCSFSTKHQKH 128

Query: 133 RVQPVKDTAHDFRAKCRNMEHALR---EKAKAFWAMRRSYEAIAKHNQVEAAWLEGRIRQ 189
            + P+K  A   R         LR   E+ +    ++ S +++    +VE  +    I  
Sbjct: 129 YICPIKKAASYHREILEGSLEPLRNNIERVEKVIILQGS-KSVELKKKVE--YKREEINS 185

Query: 190 EFDKLREFLRVEEQAILDAMAEETRQKQLLADEKMKQLTEETEVLAHEIERLQMEMKEDD 249
           EF+++R FL+ E++ IL  + +E        +E + +L++    L H +  ++ +  + +
Sbjct: 186 EFEQIRLFLQNEQEMILRQIQDEEMNILAKLNENLVELSDYVSTLKHLLREVEGKSVQSN 245

Query: 250 VSFLMKHKSRKRRLFCTMEPEPVQPGMLIDVCKYLGSL--QYRVWKKMLASVESVPFSFD 307
           +  L + KS   +      PE         + KY  SL  QY    +++   + V    D
Sbjct: 246 LELLTQAKSMHHKYQNLKCPELFS----FRLTKYGFSLPPQYSGLDRIIKPFQ-VDVILD 300

Query: 308 PNTAAGWLSVSDDLTSVTNHGYRVQV-ENPERFSSAPCLLGSRVFSQGSHAWEVALGGLQ 366
            NTA   L VS+D  +V     +  +  +P RF   P +LGS+ FS G H WEV +G   
Sbjct: 301 LNTAHPQLLVSEDRKAVRYERKKRNICYDPRRFYVCPAVLGSQRFSSGRHYWEVEVGNKP 360

Query: 367 SWRVGV-----VRVRQDSGAEGHSHSCYHDTRSGFWYVCRTQGVEGDHCVTSDPATSPLV 421
            W +GV     +R  QD  +             GFW + R         V S P T+ L+
Sbjct: 361 KWILGVCQDCLLRNWQDQPS----------VLGGFWAIGRYM---KSGYVASGPKTTQLL 407

Query: 422 LAI-PRRLRVELECEEGELSFYDAERHCHLYTFHARFGE-VRPYFYLGGARGAGPPEPLR 479
             + P ++ + L+ E G+LSFY+      LYTF+  F E V PYFY G        EPL+
Sbjct: 408 PVVKPSKIGIFLDYELGDLSFYNMNDRSILYTFNDCFTEAVWPYFYTG-----TDSEPLK 462

Query: 480 IC 481
           IC
Sbjct: 463 IC 464


>gi|157743261 tripartite motif-containing 75 [Homo sapiens]
          Length = 468

 Score =  178 bits (451), Expect = 1e-44
 Identities = 136/476 (28%), Positives = 219/476 (46%), Gaps = 38/476 (7%)

Query: 18  ELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCW-EVQVSPTCPVCKDRASPADLRTNHTLN 76
           E  C++C D   D VT+ CGHNFCR C+ + W ++Q    CPVC+ +      R+N  L 
Sbjct: 13  EAKCSICLDYLSDPVTIECGHNFCRSCIQQSWLDLQELFPCPVCRHQCQEGHFRSNTQLG 72

Query: 77  NLVE--KLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQADPRHQGHRV 134
            ++E  KLL+      R      + +C  H   LS+FC ED  +LC  C   P HQGH V
Sbjct: 73  RMIEIAKLLQSTKSNKR--KQEETTLCEKHNQPLSVFCKEDLMVLCPLCTQPPDHQGHHV 130

Query: 135 QPVKDTAHDFRAKCRNMEHALREKAKAFWAM--RRSYEAIAKHNQVEAAWLEGRIRQEFD 192
           +P++  A  +R +  +    L+++      +   +S + +     VE    E  +  EF+
Sbjct: 131 RPIEKAAIHYRKRFCSYIQPLKKQLADLQKLISTQSKKPLELREMVENQRQE--LSSEFE 188

Query: 193 KLREFLRVEEQAILDAMAEETRQKQLLADEKMKQLTEETEVLAHEIERLQMEMKEDDVSF 252
            L +FL  E+QA+L  +AEE +  Q      +   +  +  L  ++ ++    +  ++  
Sbjct: 189 HLNQFLDREQQAVLSRLAEEEKDNQQKLSANITAFSNYSATLKSQLSKVVELSELSELEL 248

Query: 253 LMKHKSRKRRLFCTMEPEPVQPGMLI----DVCKYLGSLQYRVWKKMLASVESVPFSFDP 308
           L + K     +F   E E       I    D C +    QY   ++++   + V    DP
Sbjct: 249 LSQIK-----IFYESENESSPSIFSIHLKRDGCSF--PPQYSALQRIIKKFK-VEIILDP 300

Query: 309 NTAAGWLSVSDDLTSVTNHGYRVQVEN-PERFSSAPCLLGSRVFSQGSHAWEVALGGLQS 367
            TA   L VS+D   V     + +V   P+RF+  P +LG   F  G H WE+ +G    
Sbjct: 301 ETAHPNLIVSEDKKRVRFTKRKQKVPGFPKRFTVKPVVLGFPYFHSGRHFWEIEVGDKSE 360

Query: 368 WRVGVVRVRQDSGAEGHSHSCYHDTRSGFWYVCRTQGVEGDHCVTSDPATSPLVLAI-PR 426
           W +G+ +    + A   S       +   W +      +G H   + P  +PL+L +  R
Sbjct: 361 WAIGICKDSLPTKARRPS-----SAQQECWRIELQD--DGYHAPGAFP--TPLLLEVKAR 411

Query: 427 RLRVELECEEGELSFYDAERHCHLYTFHARF-GEVRPYFYLGGARGAGPPEPLRIC 481
            + + L+ E GE+SFY+     H+ TF   F G +RPYFY+G        +PLRIC
Sbjct: 412 AIGIFLDYEMGEISFYNMAEKSHICTFTDTFTGPLRPYFYVG-----PDSQPLRIC 462


>gi|5730009 ret finger protein [Homo sapiens]
          Length = 513

 Score =  177 bits (448), Expect = 3e-44
 Identities = 146/499 (29%), Positives = 227/499 (45%), Gaps = 48/499 (9%)

Query: 16  KEELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCW-EVQVSPTCPVCKDRASPADLRTNHT 74
           ++E  C VC   F + + L CGHN C  C++RCW   + + +CP C++      +R N  
Sbjct: 11  QQETTCPVCLQYFAEPMMLDCGHNICCACLARCWGTAETNVSCPQCRETFPQRHMRPNRH 70

Query: 75  LNN---LVEKLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQADPRHQG 131
           L N   LV++L  E   G          VC  HR  L L+C ED+  +C  C     H+G
Sbjct: 71  LANVTQLVKQLRTERPSGPGGEM----GVCEKHREPLKLYCEEDQMPICVVCDRSREHRG 126

Query: 132 HRVQPVKDTAHDFRAKCRNMEHALREKAKAFWAMRRSYEAIAKHNQVEAAWLEG-RIRQE 190
           H V P+++    F+ + +N    L+ + K     RR+    A+   +    +E  +I  E
Sbjct: 127 HSVLPLEEAVEGFKEQIQNQLDHLK-RVKDLKKRRRAQGEQARAELLSLTQMEREKIVWE 185

Query: 191 FDKLREFLRVEEQAILDAMAEETRQKQLLADEKMKQLTEETEVLAHEIERLQMEMKE--- 247
           F++L   L+  E  +L  + E         +  + Q +     L+  I +L+ + ++   
Sbjct: 186 FEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIAQLEEKQQQPTR 245

Query: 248 ---DDVSFLMKHKSRKRRLFCTMEPEPVQPGMLI--DVCKYLGSLQYRVWKKMLASVE-- 300
               D+   +    R R     + P  +Q  + I    C +L     +  +KM + +E  
Sbjct: 246 ELLQDIGDTLSRAERIRIPEPWITPPDLQEKIHIFAQKCLFLTESLKQFTEKMQSDMEKI 305

Query: 301 ---------SVPFSFDPNTAAGWLSVSDDLTSVTNHGYRVQ--VENPERFSSAPCLLGSR 349
                    SV  + DP+TA   L +SD+L  V  + Y  Q   +NPERF+  PC+LGS 
Sbjct: 306 QELREAQLYSVDVTLDPDTAYPSLILSDNLRQV-RYSYLQQDLPDNPERFNLFPCVLGSP 364

Query: 350 VFSQGSHAWEVALGGLQSWRVGVVRVRQDSGAEGHSHSCYHDTRSGFWYVCRTQGVEGDH 409
            F  G H WEV +G    W +GV    +DS             ++GFW V    G E  +
Sbjct: 365 CFIAGRHYWEVEVGDKAKWTIGVC---EDSVC--RKGGVTSAPQNGFWAVSLWYGKE--Y 417

Query: 410 CVTSDPATSPLVLAIPRRLRVELECEEGELSFYDAERHCHLYTF-HARF-GEVRPYF--- 464
              + P T+  +    +R+ + L+ + GE+SFY+    CH +TF HA F G VRPYF   
Sbjct: 418 WALTSPMTALPLRTPLQRVGIFLDYDAGEVSFYNVTERCHTFTFSHATFCGPVRPYFSLS 477

Query: 465 YLGGARGAGPPEPLRICPL 483
           Y GG   A    PL ICP+
Sbjct: 478 YSGGKSAA----PLIICPM 492


>gi|217035095 tripartite motif-containing 62 [Homo sapiens]
          Length = 475

 Score =  176 bits (445), Expect = 6e-44
 Identities = 133/489 (27%), Positives = 221/489 (45%), Gaps = 34/489 (6%)

Query: 14  SFKEELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCW---EVQVSPTCPVCKDRASPADLR 70
           S K+ELLC++C   ++D V+L C H FCR C++  W   E Q +  CP C+   +   L 
Sbjct: 4   SLKDELLCSICLSIYQDPVSLGCEHYFCRRCITEHWVRQEAQGARDCPECRRTFAEPALA 63

Query: 71  TNHTLNNLVEKLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQADPRHQ 130
            +  L N+VE+      + A   + R +R C+ H  ++ LFCL D+ LLC  C     H+
Sbjct: 64  PSLKLANIVERYSSFPLD-AILNARRAARPCQAH-DKVKLFCLTDRALLCFFCDEPALHE 121

Query: 131 GHRVQPVKDTAHDFRAKCRNMEHALREKAKAFWAMRRSYEAIAKHNQVEAAWLEGRIRQE 190
            H+V  + D   + + + ++   AL++  +      +  +      +     L   I + 
Sbjct: 122 QHQVTGIDDAFDELQRELKDQLQALQDSEREHTEALQLLKRQLAETKSSTKSLRTTIGEA 181

Query: 191 FDKLREFLRVEEQAILDAMAEETRQKQLLADEKMKQLTEETEVLAHEIERLQMEMKEDD- 249
           F++L   LR  ++A+L+ +  +T +     ++K+++ +++   +    + LQ  + E D 
Sbjct: 182 FERLHRLLRERQKAMLEELEADTARTLTDIEQKVQRYSQQLRKVQEGAQILQERLAETDR 241

Query: 250 -------VSFLMKHKSRKRRLFCTMEPEPVQPGMLIDVCKYLGSLQYRVWKKMLASVESV 302
                   S   + K +      T E  P          KY G LQY +WK +   +  V
Sbjct: 242 HTFLAGVASLSERLKGKIHETNLTYEDFPTS--------KYTGPLQYTIWKSLFQDIHPV 293

Query: 303 P--FSFDPNTAAGWLSVSDDLTSVTNHGYRVQ--VENPERFSSAPCLLGSRVFSQGSHAW 358
           P   + DP TA   L +SDD T V       Q   ++P+RF     +LGS  FS G H W
Sbjct: 294 PAALTLDPGTAHQRLILSDDCTIVAYGNLHPQPLQDSPKRFDVEVSVLGSEAFSSGVHYW 353

Query: 359 EVALGGLQSWRVGVVRVRQDSGAEGHSHSCYHDTRSGFWYVCRTQGVEGDHCVTSDPATS 418
           EV +     W +G+        A     S       GF+ +    G +   C  ++P T 
Sbjct: 354 EVVVAEKTQWVIGLAH-----EAASRKGSIQIQPSRGFYCIVMHDGNQYSAC--TEPWTR 406

Query: 419 PLVLAIPRRLRVELECEEGELSFYDAERHCHLYTFHARF-GEVRPYFYLGGARGAGP-PE 476
             V     ++ V L+ ++G L FY+A+    LYTF  +F G++  YF  G +   G   +
Sbjct: 407 LNVRDKLDKVGVFLDYDQGLLIFYNADDMSWLYTFREKFPGKLCSYFSPGQSHANGKNVQ 466

Query: 477 PLRICPLHI 485
           PLRI  + I
Sbjct: 467 PLRINTVRI 475


>gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens]
          Length = 518

 Score =  174 bits (442), Expect = 1e-43
 Identities = 144/500 (28%), Positives = 226/500 (45%), Gaps = 47/500 (9%)

Query: 18  ELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWE-VQVSPTCPVCKDRASPADLRTNHTLN 76
           E  C+VC +  ++ V + CGHNFC+ C++R WE ++    CPVC+  +    LR N  L 
Sbjct: 26  EASCSVCLEYLKEPVIIECGHNFCKACITRWWEDLERDFPCPVCRKTSRYRSLRPNRQLG 85

Query: 77  NLVEKLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQADPRHQGHRVQP 136
           ++VE   + +A   +    R   +C  H   LSLFC ED+E +C  C     H+ H V P
Sbjct: 86  SMVEIAKQLQAVKRK---IRDESLCPQHHEALSLFCYEDQEAVCLICAISHTHRAHTVVP 142

Query: 137 VKDTAHDFRAKCRNMEHALREKAKAFWAMRRSYEAIAKHNQVEAAWLEGRIRQEFDKLRE 196
           + D   +++ K +     L +K +     + S E      +        +I +EF++L  
Sbjct: 143 LDDATQEYKEKLQKCLEPLEQKLQEITRCKSSEEKKPGELKRLVESRRQQILREFEELHR 202

Query: 197 FLRVEEQAILDAMAEETRQKQLLADEKMKQLTEETEVLAH---EIE----RLQMEMKEDD 249
            L  E+Q +L  + EE +       E    L ++   LAH   E+E    +   EM +D 
Sbjct: 203 RLDEEQQVLLSRLEEEEQDILQRLRENAAHLGDKRRDLAHLAAEVEGKCLQSGFEMLKDV 262

Query: 250 VSFLMKHKSRK----RRLFCTMEPEPVQPGML--IDVCKYLGSL---------------- 287
            S L K+  RK        C  + + +  G++  I+ C+ + ++                
Sbjct: 263 KSTLEKNIPRKFGGSLSTICPRDHKALL-GLVKEINRCEKVKTMEVTSVSIELEKNFSNF 321

Query: 288 --QYRVWKKMLASVESVPFSFDPNTAAGWLSVSDDLTSVTNHGYRVQ--VENPERFSSAP 343
             QY   +K+L  +     + DP TA   L +S+D  SV     R++   + P RF+  P
Sbjct: 322 PRQYFALRKILKQL-IADVTLDPETAHPNLVLSEDRKSVKFVETRLRDLPDTPRRFTFYP 380

Query: 344 CLLGSRVFSQGSHAWEVALGGLQSWRVGVVRVRQDSGAEGHSHSCYHDTRSGFWYVCRTQ 403
           C+L +  F+ G H WEV +G    W VGV R   DS +     +   +T  G+W V    
Sbjct: 381 CVLATEGFTSGRHYWEVEVGDKTHWAVGVCR---DSVSRKGELTPLPET--GYWRVRLWN 435

Query: 404 GVEGDHCVTSDPATSPLVLAIPRRLRVELECEEGELSFYDAERHCHLYTFHARFGE-VRP 462
           G    +  T+ P T   +   P+R+ + L+ E G LSFY+     H+YTF   F E + P
Sbjct: 436 G--DKYAATTTPFTPLHIKVKPKRVGIFLDYEAGTLSFYNVTDRSHIYTFTDTFTEKLWP 493

Query: 463 YFYLGGARGAGPPEPLRICP 482
            FY G   G     PL I P
Sbjct: 494 LFYPGIRAGRKNAAPLTIRP 513


>gi|112421127 tripartite motif-containing 58 [Homo sapiens]
          Length = 486

 Score =  172 bits (436), Expect = 6e-43
 Identities = 136/473 (28%), Positives = 208/473 (43%), Gaps = 45/473 (9%)

Query: 11  PSRSFKEELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWEVQVSP-----TCPVCKDRAS 65
           P    +E+  C VC D  ++ V++ CGH+FC  C+S   E           CP C+    
Sbjct: 6   PGERLREDARCPVCLDFLQEPVSVDCGHSFCLRCISEFCEKSDGAQGGVYACPQCRGPFR 65

Query: 66  PADLRTNHTLNNLVEKLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQA 125
           P+  R N  L  LVE + R             +R C  H   LS FC ED+  LC  C A
Sbjct: 66  PSGFRPNRQLAGLVESVRRLGLGAGPG-----ARRCARHGEDLSRFCEEDEAALCWVCDA 120

Query: 126 DPRHQGHRVQPVKDTAHDFRAKC--------RNMEHALREKAKAFWAMRRSYEAIAKHNQ 177
            P H+ HR  P+++ A  ++ K         + +E AL ++A          + +    +
Sbjct: 121 GPEHRTHRTAPLQEAAGSYQVKLQMALELMRKELEDALTQEANV------GKKTVIWKEK 174

Query: 178 VEAAWLEGRIRQEFDKLREFLRVEEQAILDAMAEETRQKQLLADEKMKQLTEETEVLAHE 237
           VE      R R EF+K R FL  EEQ  L  +  E R       E   +L ++++ L   
Sbjct: 175 VEMQ--RQRFRLEFEKHRGFLAQEEQRQLRRLEAEERATLQRLRESKSRLVQQSKALKEL 232

Query: 238 IERLQMEMKEDDVSFL--MKHKSRKRRLFCTMEPEPVQPGMLIDVCKYLGSLQYRVWKKM 295
            + LQ   +   +  L  ++    + +    +E E + P  L   C   G       ++ 
Sbjct: 233 ADELQERCQRPALGLLEGVRGVLSRSKAVTRLEAENI-PMELKTACCIPG-------RRE 284

Query: 296 LASVESVPFSFDPNTAAGWLSVSDDLTSVTN-HGYRVQVENPERFSSAPCLLGSRVFSQG 354
           L     V    DP TA   L ++ DL SV +   +R    NPERF + PC+LG + FS G
Sbjct: 285 LLRKFQVDVKLDPATAHPSLLLTADLRSVQDGEPWRDVPNNPERFDTWPCILGLQSFSSG 344

Query: 355 SHAWEVALGGLQSWRVGVVRVRQDSGAEGHSHSCYHDTRSGFWYVCRTQGVEGDHCVTSD 414
            H WEV +G    W +GV +       E           +G W +   +G   ++ V + 
Sbjct: 345 RHYWEVLVGEGAEWGLGVCQDTLPRKGE-----TTPSPENGVWALWLLKG--NEYMVLAS 397

Query: 415 PATSPLVLAIPRRLRVELECEEGELSFYDAERHCHLYTFHARF-GEVRPYFYL 466
           P+   L L  PR + + L+ E GE+SFY+     ++YTF+  F G +RPYF++
Sbjct: 398 PSVPLLQLESPRCIGIFLDYEAGEISFYNVTDGSYIYTFNQLFSGLLRPYFFI 450


>gi|88999601 tripartite motif-containing 69 isoform a [Homo sapiens]
          Length = 500

 Score =  166 bits (421), Expect = 3e-41
 Identities = 142/483 (29%), Positives = 215/483 (44%), Gaps = 44/483 (9%)

Query: 18  ELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWEVQVSPT-CPVCKDRASPADLRTNHTLN 76
           EL C +C D FRD + L CGHNFC  C+   W +Q   T CP CK      +   N  L+
Sbjct: 38  ELHCPLCNDWFRDPLMLSCGHNFCEACIQDFWRLQAKETFCPECKMLCQYNNCTFNPVLD 97

Query: 77  NLVEKLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQADPR---HQGHR 133
            LVEK+        +    +    C  H   L LF   D +L+C  C+ D R    Q   
Sbjct: 98  KLVEKI-------KKLPLLKGHPQCPEHGENLKLFSKPDGKLICFQCK-DARLSVGQSKE 149

Query: 134 VQPVKDTAHDFRAKCRNMEHALREKAKAFWAMRR-SYEAIAKHNQVEAAWLEGRIRQEFD 192
              + D  H F  +    +  L    K    +R    EAIA H +     L+  +  EF 
Sbjct: 150 FLQISDAVHFFTEELAIQQGQLETTLKELQTLRNMQKEAIAAHKE-NKLHLQQHVSMEFL 208

Query: 193 KLREFLRVEEQAILDAMAEETRQKQLLADEKMKQLTEETEVLAHEIERLQMEMKED---- 248
           KL +FL  +E+ IL  + EE +      +  + QL E+  +    +  +Q + ++     
Sbjct: 209 KLHQFLHSKEKDILTELREEGKALNEEMELNLSQLQEQCLLAKDMLVSIQAKTEQQNSFD 268

Query: 249 ---DVSFLMKHKSRKRRLFCTMEPEPVQPGMLIDVCKYLGSLQYRVWKKMLASV--ESVP 303
              D++ L+    +  ++  T E         +++ +Y G +QY VW++M  ++     P
Sbjct: 269 FLKDITTLLHSLEQGMKVLATRE----LISRKLNLGQYKGPIQYMVWREMQDTLCPGLSP 324

Query: 304 FSFDPNTAAGWLSVSDDLTSVTNHG--YRVQVENPERFSSAPCLLGSRVFSQGSHAWEVA 361
            + DP TA   L +S   TSV  HG   ++  ++PERF S+  +LGSR F+ G   WEV 
Sbjct: 325 LTLDPKTAHPNLVLSKSQTSVW-HGDIKKIMPDDPERFDSSVAVLGSRGFTSGKWYWEVE 383

Query: 362 LGGLQSWRVGVVR---VRQDSGAEGHSHSCYHDTRSGFWYVCRTQGVEGDHCVTSDPATS 418
           +     W VGVVR   +R+         SC      GFW +      + D      P+ S
Sbjct: 384 VAKKTKWTVGVVRESIIRKG--------SCPLTPEQGFWLLRLRN--QTDLKALDLPSFS 433

Query: 419 PLVLAIPRRLRVELECEEGELSFYDAERHCHLYTFHARFGE-VRPYFYLGGARGAGPPEP 477
             +     ++ + L+ E G+LSFY+A+   H+YTF   F E + PYF      G    EP
Sbjct: 434 LTLTNNLDKVGIYLDYEGGQLSFYNAKTMTHIYTFSNTFMEKLYPYFCPCLNDGGENKEP 493

Query: 478 LRI 480
           L I
Sbjct: 494 LHI 496


>gi|44680122 tripartite motif-containing 7 isoform 1 [Homo sapiens]
          Length = 511

 Score =  166 bits (419), Expect = 6e-41
 Identities = 139/488 (28%), Positives = 206/488 (42%), Gaps = 56/488 (11%)

Query: 18  ELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWE----------VQVSP---TCPVCKDRA 64
           E  C++C + FR+ V++ CGH+FCR C+ RCWE           +  P    CP C++ A
Sbjct: 26  EATCSICLELFREPVSVECGHSFCRACIGRCWERPGAGSVGAATRAPPFPLPCPQCREPA 85

Query: 65  SPADLRTNHTLNNLVEKLLR------------EEAEGARWTSYRFSRVCRLHRGQLSLFC 112
            P+ LR N  L  +   L R             +A  AR  + R    C  H     L+C
Sbjct: 86  RPSQLRPNRQLAAVATLLRRFSLPAAAPGEHGSQAAAARAAAAR----CGQHGEPFKLYC 141

Query: 113 LEDKELLCCSCQADPRHQGHRVQPVKDTAHDFRAKCRNMEHALREKAKAFWAMRRSYEAI 172
            +D   +C  C     H+ H V P+ +   + +    +    L+++ +     R + +  
Sbjct: 142 QDDGRAICVVCDRAREHREHAVLPLDEAVQEAKELLESRLRVLKKELEDCEVFRSTEKKE 201

Query: 173 AKHNQVEAAWLEGRIRQEFDKLREFLRVEEQAILDAMAEETRQKQLLADEKMKQLTEETE 232
           +K    + A  + ++  EF  LR FL  +E  +L  + E +R+     +E + QL  E  
Sbjct: 202 SKELLKQMAAEQEKVGAEFQALRAFLVEQEGRLLGRLEELSREVAQKQNENLAQLGVEIT 261

Query: 233 VLAHEIERLQMEMKEDDVSFLMKHKSRKRRLFCTMEPEPVQPGMLIDVCKYLGSLQYRVW 292
            L+    ++Q   ++ D+ FL + KS   R      P+P      +    +  SL+  V 
Sbjct: 262 QLSKLSSQIQETAQKPDLDFLQEFKSTLSRCSNVPGPKPTTVSSEMKNKVWNVSLKTFVL 321

Query: 293 KKMLASV-----------ESVPFSFDPNTAAGWLSVSDDLTSVTNHGYRVQ--VENPERF 339
           K ML              E V  + DP+TA   L +S DL  V   G R Q    +P RF
Sbjct: 322 KGMLKKFKEDLRGELEKEEKVELTLDPDTANPRLILSLDLKGV-RLGERAQDLPNHPCRF 380

Query: 340 SSAPCLLGSRVFSQGSHAWEVALGGLQSWRVGVVR--VRQDSGAEGHSHSCYHDTRSGFW 397
            +   +L S  FS G H WEV +G    W  GV R  VR+                 G W
Sbjct: 381 DTNTRVLASCGFSSGRHHWEVEVGSKDGWAFGVARESVRRKGLTP-------FTPEEGVW 433

Query: 398 YVCRTQGVEGDHCVTSDPATSPLVLAIPRRLRVELECEEGELSFYDAERHCHLYTFHARF 457
            +   Q   G +   + P  SPL      R+RV L+ E G +SFY  E   HLYTF   F
Sbjct: 434 AL---QLNGGQYWAVTSPERSPLSCGHLSRVRVALDLEVGAVSFYAVEDMRHLYTFRVNF 490

Query: 458 GE-VRPYF 464
            E V P F
Sbjct: 491 QERVFPLF 498


>gi|37622899 ring finger protein 137 [Homo sapiens]
          Length = 485

 Score =  164 bits (416), Expect = 1e-40
 Identities = 136/494 (27%), Positives = 224/494 (45%), Gaps = 51/494 (10%)

Query: 17  EELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWEVQVSP-----TCPVCKDRASPADLRT 71
           EE+ C +C    R+ +++ CGH+FC  C+S  WE+         TCP+C+    P +LR 
Sbjct: 12  EEVACPICMTFLREPMSIDCGHSFCHSCLSGLWEIPGESQNWGYTCPLCRAPVQPRNLRP 71

Query: 72  NHTLNNLVEK--LLR-EEAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQADPR 128
           N  L N+VEK  LLR     G +        +C  H  +L +FC ED  ++C +C   P 
Sbjct: 72  NWQLANVVEKVRLLRLHPGMGLK------GDLCERHGEKLKMFCKEDVLIMCEACSQSPE 125

Query: 129 HQGHRVQPVKDTAHDFRAKCRN-MEHALREKAKAFWAMRRSYEAIAKHNQVEAAWLEGRI 187
           H+ H V P++D A +++ +    +EH  +E+ +A W +           +++    +  I
Sbjct: 126 HEAHSVVPMEDVAWEYKWELHEALEHLKKEQEEA-WKLEVGERKRTATWKIQVETRKQSI 184

Query: 188 RQEFDKLREFLR----------VEEQAILDAMAEETRQKQLLADEKMKQLTEETEVLAHE 237
             EF+K +  L            E  A L ++  E  +     +    +L ++++VL   
Sbjct: 185 VWEFEKYQRLLEKKQPPHRQLGAEVAAALASLQREAAETMQKLELNHSELIQQSQVLWRM 244

Query: 238 IERLQMEMKEDDVSFLM---KHKSRKRRLFCTMEPEPVQPGMLIDVCKYLGSLQYRVWKK 294
           I  L+ E  +  V +++   +    + + +   +PEP+   +  D C+ LG  +  + K 
Sbjct: 245 IAELK-ERSQRPVRWMLQDIQEVLNRSKSWSLQQPEPISLELKTD-CRVLGLRE--ILKT 300

Query: 295 MLASVESVPFSFDPNTAAGWLSVSDDLTSVTNHGYRVQ--VENPERFSSAPCLLGSRVFS 352
             A V       DP+TA   L VS+D   V ++G   Q   +NPERF     +LGS+  S
Sbjct: 301 YAADVR-----LDPDTAYSRLIVSEDRKRV-HYGDTNQKLPDNPERFYRYNIVLGSQCIS 354

Query: 353 QGSHAWEVALGGLQSWRVGVVRVRQDSGAEGHSHSCYHDTRSGFWYVCRTQGVEGDHCVT 412
            G H WEV +G    W +GV +   D          Y     GFW +   +G E      
Sbjct: 355 SGRHYWEVEVGDRSEWGLGVCKQNVD-----RKEVVYLSPHYGFWVIRLRKGNEYRAGTD 409

Query: 413 SDPATSPLVLAIPRRLRVELECEEGELSFYD-AERHCHLYTF--HARFGEVRPYFYLGGA 469
             P  S  +   PRR+ + ++ E  ++SFY+  +   H++TF  +   G + PYF    +
Sbjct: 410 EYPILS--LPVPPRRVGIFVDYEAHDISFYNVTDCGSHIFTFPRYPFPGRLLPYFSPCYS 467

Query: 470 RGAGPPEPLRICPL 483
            G     PL IC L
Sbjct: 468 IGTNNTAPLAICSL 481


>gi|30023818 tripartite motif protein 50A [Homo sapiens]
          Length = 487

 Score =  159 bits (401), Expect = 7e-39
 Identities = 137/469 (29%), Positives = 202/469 (43%), Gaps = 55/469 (11%)

Query: 19  LLCAVCYDPFRDAVTLRCGHNFCRGC-VSRCWEVQVSPTCPVCKDRASPADLRTNHTLNN 77
           L C +C + F++ + L+CGH++C+GC VS    +     CPVC+     +    N +L  
Sbjct: 14  LQCPICLEVFKEPLMLQCGHSYCKGCLVSLSCHLDAELRCPVCRQAVDGSSSLPNVSLAR 73

Query: 78  LVEKLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQADPRHQGHRVQPV 137
           ++E L        R       +VC  HR  LSLFC +D+EL+C  C     HQ H V PV
Sbjct: 74  VIEAL--------RLPGDPEPKVCVHHRNPLSLFCEKDQELICGLCGLLGSHQHHPVTPV 125

Query: 138 KDTAHDFRAKCRNMEHALREKAKAFWAMRRSYEAIAK--HNQV----EAAWLEGRIRQEF 191
                  + +   +   L+++ K      +  E IAK  +N+     E+      IR+EF
Sbjct: 126 STVYSRMKEELAALISELKQEQK------KVDELIAKLVNNRTRIVNESDVFSWVIRREF 179

Query: 192 DKLREFLRVEEQAILDAMAEETRQKQLLADEKMKQLTEETEVLAHEIERLQMEMKEDDVS 251
            +L   +  E+   L+ +   TR      D +++Q     E LA     L+    ED   
Sbjct: 180 QELHHLVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERLAQAECVLEQFGNEDHHK 239

Query: 252 FLMKHKS--------RKRRLFCTMEPEPVQPGMLIDVCKYLGSLQYRVWKKMLASVESVP 303
           F+ K  S        + R L     P   +PG+      +   ++  VWK++   V   P
Sbjct: 240 FIRKFHSMASRAEMPQARPLEGAFSPISFKPGL------HQADIKLTVWKRLFRKVLPAP 293

Query: 304 --FSFDPNTAAGWLSVSDDLTSVTNHGYRVQ--VENPERFSSAPCLLGSRVFSQGSHAWE 359
                DP TA   L +S   T V   G   Q     PERF  + C+L SR FS G H WE
Sbjct: 294 EPLKLDPATAHPLLELSKGNT-VVQCGLLAQRRASQPERFDYSTCVLASRGFSCGRHYWE 352

Query: 360 VALGGLQSWRVGVVRVRQDSGAEGHSHSCYHDTRSGFWYVCRTQG--VEGDHCVTSDPAT 417
           V +G    WR+GV++     G              G W +   +G   E   C    P  
Sbjct: 353 VVVGSKSDWRLGVIK-----GTASRKGKLNRSPEHGVWLIGLKEGRVYEAFAC----PRV 403

Query: 418 SPLVLAIPRRLRVELECEEGELSFYDAERHCH---LYTFHARF-GEVRP 462
              V   P R+ + L  E+GEL+F+DA+R      LYTF A F G++ P
Sbjct: 404 PLPVAGHPHRIGLYLHYEQGELTFFDADRPDDLRPLYTFQADFQGKLYP 452


>gi|68160933 tripartite motif-containing 17 isoform 1 [Homo sapiens]
          Length = 477

 Score =  153 bits (386), Expect = 4e-37
 Identities = 130/492 (26%), Positives = 214/492 (43%), Gaps = 69/492 (14%)

Query: 12  SRSFKEELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWEV----------QVSPTCPVCK 61
           +R  +EE  C++C D F D V   CGHNFCR C+   WE           + S  CP C+
Sbjct: 7   ARKLQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSWEKARGKKGRRKRKGSFPCPECR 66

Query: 62  DRASPADLRTNHTLNNLVEKLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLCC 121
           + +   +L  N  L  + E  + ++  G +        +C+ H   L LFC +D+  +C 
Sbjct: 67  EMSPQRNLLPNRLLTKVAE--MAQQHPGLQKQD-----LCQEHHEPLKLFCQKDQSPICV 119

Query: 122 SCQADPRHQGHRVQPVKDTAHDFRAKCRNMEHALREKAKAFWAMRRSYEAIAKHNQVEAA 181
            C+    H+ HRV P ++    ++ K       LRE+      + R+    A+  Q  A 
Sbjct: 120 VCRESREHRLHRVLPAEEAVQGYKLKLEEDMEYLREQ------ITRTGNLQAREEQSLAE 173

Query: 182 WLEGRIRQ-------EFDKLREFLRVEEQAILDAMAEETRQKQLLADEKMKQLTEETEVL 234
           W +G++++       EF+K+  +L  EEQ +L A+  E  +      E +  L  +    
Sbjct: 174 W-QGKVKERRERIVLEFEKMNLYLVEEEQRLLQALETEEEETASRLRESVACLDRQ---- 228

Query: 235 AHEIERLQMEMKEDDVSFL------MKHKSRKRRLFCTMEPEPVQPGMLIDVCKYLGSLQ 288
            H +E L ++++E            MK    ++       PE   P     VC+  G  Q
Sbjct: 229 GHSLELLLLQLEERSTQGPLQMLQDMKEPLSRKNNVSVQCPEVAPPTRPRTVCRVPG--Q 286

Query: 289 YRVWKKMLASVESVPFSFDPNTAAGWLSVSDDL------TSVTNHGYRVQVENPERFSSA 342
             V +  L  V  VP   D  +A  +L + +        +S    G+     + +RF + 
Sbjct: 287 IEVLRGFLEDV--VP---DATSAYPYLLLYESRQRRYLGSSPEGSGFC----SKDRFVAY 337

Query: 343 PCLLGSRVFSQGSHAWEVALG--GLQSWRVGVVRVRQDSGAEGHSHSCYHDTRSGFWYVC 400
           PC +G   FS G H WEV +   G   W +GV   R +   +     C     +GFW V 
Sbjct: 338 PCAVGQTAFSSGRHYWEVGMNITGDALWALGV--CRDNVSRKDRVPKC---PENGFWVVQ 392

Query: 401 RTQGVEGDHCVTSDPATSPLVLAIPRRLRVELECEEGELSFYDAERHCHLYTF-HARF-G 458
            ++G +  +  T    T  +++  P  + + L+ E GE+SFY      HL+T+  A F G
Sbjct: 393 LSKGTK--YLSTFSALTPVMLMEPPSHMGIFLDFEAGEVSFYSVSDGSHLHTYSQATFPG 450

Query: 459 EVRPYFYLGGAR 470
            ++P+F LG  +
Sbjct: 451 PLQPFFCLGAPK 462


>gi|7705825 tripartite motif-containing 17 isoform 1 [Homo sapiens]
          Length = 477

 Score =  153 bits (386), Expect = 4e-37
 Identities = 130/492 (26%), Positives = 214/492 (43%), Gaps = 69/492 (14%)

Query: 12  SRSFKEELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWEV----------QVSPTCPVCK 61
           +R  +EE  C++C D F D V   CGHNFCR C+   WE           + S  CP C+
Sbjct: 7   ARKLQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSWEKARGKKGRRKRKGSFPCPECR 66

Query: 62  DRASPADLRTNHTLNNLVEKLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLCC 121
           + +   +L  N  L  + E  + ++  G +        +C+ H   L LFC +D+  +C 
Sbjct: 67  EMSPQRNLLPNRLLTKVAE--MAQQHPGLQKQD-----LCQEHHEPLKLFCQKDQSPICV 119

Query: 122 SCQADPRHQGHRVQPVKDTAHDFRAKCRNMEHALREKAKAFWAMRRSYEAIAKHNQVEAA 181
            C+    H+ HRV P ++    ++ K       LRE+      + R+    A+  Q  A 
Sbjct: 120 VCRESREHRLHRVLPAEEAVQGYKLKLEEDMEYLREQ------ITRTGNLQAREEQSLAE 173

Query: 182 WLEGRIRQ-------EFDKLREFLRVEEQAILDAMAEETRQKQLLADEKMKQLTEETEVL 234
           W +G++++       EF+K+  +L  EEQ +L A+  E  +      E +  L  +    
Sbjct: 174 W-QGKVKERRERIVLEFEKMNLYLVEEEQRLLQALETEEEETASRLRESVACLDRQ---- 228

Query: 235 AHEIERLQMEMKEDDVSFL------MKHKSRKRRLFCTMEPEPVQPGMLIDVCKYLGSLQ 288
            H +E L ++++E            MK    ++       PE   P     VC+  G  Q
Sbjct: 229 GHSLELLLLQLEERSTQGPLQMLQDMKEPLSRKNNVSVQCPEVAPPTRPRTVCRVPG--Q 286

Query: 289 YRVWKKMLASVESVPFSFDPNTAAGWLSVSDDL------TSVTNHGYRVQVENPERFSSA 342
             V +  L  V  VP   D  +A  +L + +        +S    G+     + +RF + 
Sbjct: 287 IEVLRGFLEDV--VP---DATSAYPYLLLYESRQRRYLGSSPEGSGFC----SKDRFVAY 337

Query: 343 PCLLGSRVFSQGSHAWEVALG--GLQSWRVGVVRVRQDSGAEGHSHSCYHDTRSGFWYVC 400
           PC +G   FS G H WEV +   G   W +GV   R +   +     C     +GFW V 
Sbjct: 338 PCAVGQTAFSSGRHYWEVGMNITGDALWALGV--CRDNVSRKDRVPKC---PENGFWVVQ 392

Query: 401 RTQGVEGDHCVTSDPATSPLVLAIPRRLRVELECEEGELSFYDAERHCHLYTF-HARF-G 458
            ++G +  +  T    T  +++  P  + + L+ E GE+SFY      HL+T+  A F G
Sbjct: 393 LSKGTK--YLSTFSALTPVMLMEPPSHMGIFLDFEAGEVSFYSVSDGSHLHTYSQATFPG 450

Query: 459 EVRPYFYLGGAR 470
            ++P+F LG  +
Sbjct: 451 PLQPFFCLGAPK 462


>gi|15011941 tripartite motif protein TRIM4 isoform beta [Homo
           sapiens]
          Length = 474

 Score =  145 bits (365), Expect = 1e-34
 Identities = 132/479 (27%), Positives = 191/479 (39%), Gaps = 46/479 (9%)

Query: 12  SRSFKEELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWEVQVSP-TCPVCKDRASPADLR 70
           +   +EEL C +C D F+D V++ CGHNFCRGC+ R W     P  CP C+  ++PA LR
Sbjct: 3   AEDIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSAPAALR 62

Query: 71  TNHTLNNLVEKLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQADPRHQ 130
            N  L  L EK  R               +C  H   L LFC +D+  +C  C+    HQ
Sbjct: 63  PNWALARLTEKTQRRRLGPVP------PGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQ 116

Query: 131 GHRVQPVKDTAHDFRAKCRNMEHALREKAKAFWAMRRSYEAIAKHNQVEAAWLEGRIRQE 190
            H + P+ +    +R K    +  L  K K    ++      A   + +      RI  E
Sbjct: 117 THAMAPIDEAFESYREKLLKSQRNLVAKMKKVMHLQDVEVKNATQWKDKIKSQRMRISTE 176

Query: 191 FDKLREFLRVEEQAILDAMAEETRQKQLLADEKMKQLTEETEVLAHEI---ERLQMEMKE 247
           F KL  FL  EE   L  + +E        +E  K+L E T  L   I   ++L +E+ E
Sbjct: 177 FSKLHNFLVEEEDLFLQRLNKE-------EEETKKKLNENTLKLNQTIASLKKLILEVGE 229

Query: 248 DDVSFLMKHKSRKRRLFCTMEPEPVQPGMLIDVCKYLGSLQYRVWKKMLASVESVPFSFD 307
              +  ++     + +    E + V     ++  K     Q  + K+ML   + V  +  
Sbjct: 230 KSQAPTLELLQNPKEVLTRSEIQDV--NYSLEAVKVKTVCQIPLMKEMLKRFQ-VAVNLA 286

Query: 308 PNTAAGWLSVSDDLTSVTN-------------HGYRVQVENP------ERFSSAPCLLGS 348
            +TA   L  S +   V N               Y     NP      ERF   PC+LG 
Sbjct: 287 EDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAGWRNPQKTAFVERFQHLPCVLGK 346

Query: 349 RVFSQGSHAWEVALGGLQSWRVGVVRVRQDSGAEGHSHSCYHDTRSGFWYVCRTQGVEGD 408
            VF+ G H WEV         VGV R        G +         G W +       G 
Sbjct: 347 NVFTSGKHYWEVESRDSLEVAVGVCR----EDVMGITDRSKMSPDVGIWAI--YWSAAGY 400

Query: 409 HCVTSDPATSPLVLAIPRRLRVELECEEGELSFYDAERHCHLYTFH-ARFGEVRPYFYL 466
             +   P T         R+ V L+   G +SFY A    HL+TF  +    +RP+F+L
Sbjct: 401 WPLIGFPGTPTQQEPALHRVGVYLDRGTGNVSFYSAVDGVHLHTFSCSSVSRLRPFFWL 459


>gi|157426898 tripartite motif-containing 10 isoform 1 [Homo
           sapiens]
          Length = 481

 Score =  144 bits (364), Expect = 1e-34
 Identities = 132/486 (27%), Positives = 213/486 (43%), Gaps = 53/486 (10%)

Query: 14  SFKEELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWEV-----QVSPTCPVCKDRASPAD 68
           S  +E+ C +C    R+ VT+ CGHNFCR C++R  E+     + SPTCP+CK+   P  
Sbjct: 9   SLADEVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLCKEPFRPGS 68

Query: 69  LRTNHTLNNLVEKLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQADPR 128
            R N  L N+VE +  E  +           VC+ H  ++  FC +D+  LC  C+    
Sbjct: 69  FRPNWQLANVVENI--ERLQLVSTLGLGEEDVCQEHGEKIYFFCEDDEMQLCVVCREAGE 126

Query: 129 HQGHRVQPVKDTAHDFRAKCRNMEHALREKAKAFWAMRRSYEAIAKHNQVEAAWLEGRIR 188
           H  H ++ ++D A  +R +       LR++ +    ++       +    + +    ++ 
Sbjct: 127 HATHTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQSRENKRMQVLLTQVSTKRQQVI 186

Query: 189 QEFDKLREFLRVEEQAILDAMAEE-----TRQK---QLLADEKMKQLTEETEVLAHEIER 240
            EF  LR+FL  E+Q+IL A  E       RQ+    LL   ++ + +   E L  + ER
Sbjct: 187 SEFAHLRKFLE-EQQSILLAQLESQDGDILRQRDEFDLLVAGEICRFSALIEELEEKNER 245

Query: 241 LQMEMKEDDVSFLMKHKSRKRRLFCTMEPE-------------PVQPGMLIDVCKYLGSL 287
              E+  D  S L++ ++RK R    + PE             P+Q  M + + K    L
Sbjct: 246 PARELLTDIRSTLIRCETRKCRKPVAVSPELGQRIRDFPQQALPLQREMKMFLEKLCFEL 305

Query: 288 QYRVWKKMLASVESVPFSFDPNTAAGWLSVSDD-LTSVTNHGYRVQVENPERFSSAPCLL 346
            Y          E    S DP T+   L +S+D   +  ++ ++   +NP+RF  A C+L
Sbjct: 306 DY----------EPAHISLDPQTSHPKLLLSEDHQRAQFSYKWQNSPDNPQRFDRATCVL 355

Query: 347 GSRVFSQGSHAWEVALGGLQSWRVGVVRVRQDSGAEGHSHSCYHDTRSGFWYVCRTQGVE 406
                + G H W V++         V  V +D   +G           G W V    G  
Sbjct: 356 AHTGITGGRHTWVVSIDLAHGGSCTVGVVSEDVQRKGELRL---RPEEGVWAVRLAWG-- 410

Query: 407 GDHCVTSDPATSPLVLAI---PRRLRVELECEEGELSFYDAERHCHLYTFHARF-GEVRP 462
                 S   + P  L +   PR++RV L+ E G ++F +A     +YTF A F  +V P
Sbjct: 411 ----FVSALGSFPTRLTLKEQPRQVRVSLDYEVGWVTFTNAVTREPIYTFTASFTRKVIP 466

Query: 463 YFYLGG 468
           +F L G
Sbjct: 467 FFGLWG 472


>gi|5454014 tripartite motif-containing 38 [Homo sapiens]
          Length = 465

 Score =  141 bits (355), Expect = 2e-33
 Identities = 120/467 (25%), Positives = 205/467 (43%), Gaps = 37/467 (7%)

Query: 12  SRSFKEELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWEV-------QVSPTCPVCKDRA 64
           ++   EE  C++C     + V++ CGH++C  C++  ++        Q +  CP C+   
Sbjct: 7   TKKMMEEATCSICLSLMTNPVSINCGHSYCHLCITDFFKNPSQKQLRQETFCCPQCRAPF 66

Query: 65  SPADLRTNHTLNNLVEKLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQ 124
               LR N  L +L+E L   + E +          C  H  Q  LFC ++ +L+C  C+
Sbjct: 67  HMDSLRPNKQLGSLIEALKETDQEMS----------CEEHGEQFHLFCEDEGQLICWRCE 116

Query: 125 ADPRHQGHRVQPVKDTAHDFRAKCRNMEHALREKAKAFWAMRRSYEAIAKHNQVEAAWLE 184
             P+H+GH    V+D    ++ K +     L++        + S        + +     
Sbjct: 117 RAPQHKGHTTALVEDVCQGYKEKLQKAVTKLKQLEDRCTEQKLSTAMRITKWKEKVQIQR 176

Query: 185 GRIRQEFDKLREFLRVEEQAILDAMAEETRQK-QLLADEKMKQLTEETEVLAHEIERLQM 243
            +IR +F  L+ FL  EE++ L  + +E +Q    L D +     +  E+ +H +E L+ 
Sbjct: 177 QKIRSDFKNLQCFLHEEEKSYLWRLEKEEQQTLSRLRDYEAGLGLKSNELKSHILE-LEE 235

Query: 244 EMKEDDVSFLMKHKSRKRRLFCTMEPEPVQPGMLIDVCKYLGSLQYRVWKKMLASVESVP 303
           + +      L        R +           + +     +  L + V KKML S   V 
Sbjct: 236 KCQGSAQKLLQNVNDTLSRSWAVKLETSEAVSLELHTMCNVSKLYFDV-KKMLRS-HQVS 293

Query: 304 FSFDPNTAAGWLSVSDDLTSVTNHGY--RVQVENPERFSSAPCLLGSRVFSQGSHAWEVA 361
            + DP+TA   L +S+D   VT  GY    Q  +  RF++ PC+LG   F+ G   +EV 
Sbjct: 294 VTLDPDTAHHELILSEDRRQVT-RGYTQENQDTSSRRFTAFPCVLGCEGFTSGRRYFEVD 352

Query: 362 LGGLQSWRVGVVRVRQDSGAEGHSHSCYHDTRSGFW--YVCRTQGVEGDHCVTSDPATSP 419
           +G    W +GV       G          + +SGFW   +C+ +G    +   + P TS 
Sbjct: 353 VGEGTGWDLGVCMENVQRGT-----GMKQEPQSGFWTLRLCKKKG----YVALTSPPTSL 403

Query: 420 LVLAIPRRLRVELECEEGELSFYDAERHCHLYTF-HARFGE-VRPYF 464
            +   P  + + L+ E G +SFY+    CH++TF  A F + +RPYF
Sbjct: 404 HLHEQPLLVGIFLDYEAGVVSFYNGNTGCHIFTFPKASFSDTLRPYF 450


>gi|18079262 tripartite motif-containing 6 isoform 2 [Homo sapiens]
          Length = 488

 Score =  139 bits (351), Expect = 4e-33
 Identities = 125/473 (26%), Positives = 215/473 (45%), Gaps = 34/473 (7%)

Query: 16  KEELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWEVQV-----SPTCPVCKDRASPADLR 70
           +EE+ C +C +   + +++ CGH+FC+ C++      V       +CPVC+    P +LR
Sbjct: 10  REEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQPGNLR 69

Query: 71  TNHTLNNLVEKLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQADPRHQ 130
            N  L N+V +L RE   G        + +C  H  +L LFC ED +++C  C+    H+
Sbjct: 70  PNRHLANIVRRL-REVVLGPG--KQLKAVLCADHGEKLQLFCQEDGKVICWLCERSQEHR 126

Query: 131 GHRVQPVKDTAHDFRAKCRNMEHALR---EKAKAFWAMRRSYEAIAKHNQVEAAWLEGRI 187
           GH    V++ A +++ K +     L+   ++A+   A  R  +   K NQ+E      RI
Sbjct: 127 GHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWK-NQMEPE--RCRI 183

Query: 188 RQEFDKLREFLRVEEQAILDAMAEETRQKQLLADEKMKQLTEETEVLAHEIERLQMEMKE 247
           + EF++LR  L   EQ  L  + +E ++   + +E    L  +T+ L   I  L+   + 
Sbjct: 184 QTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRCQG 243

Query: 248 DDVSFLMKHKS-RKRRLFCTMEPEPVQPGMLIDVCKYLGSLQYRVWKKMLASVES--VPF 304
             +  L       +R  F T+      P  L  + +     +     + L  V+S  V  
Sbjct: 244 STMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYWVDV 303

Query: 305 SFDPNTAAGWLSVSDDLTSVTNHGYRVQVENPERFSSAPCLLGSRVFSQGSHAWEVALGG 364
           + +P+TA   L ++ +   V   G +V   +         +LGS+ FS G H WEV +  
Sbjct: 304 TLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEKHYDCSVLGSQHFSSGKHYWEVDVAK 363

Query: 365 LQSWRVGVV------RVRQDSGAEGHSHSCYHDTRSGFWYVCRTQGVEGDHCVTSDPATS 418
             +W +GV           +  A+ HS    +  +SG+W +    G++ +H   +   +S
Sbjct: 364 KTAWILGVCSNSLGPTFSFNHFAQNHSAYSRYQPQSGYWVI----GLQHNHEYRAYEDSS 419

Query: 419 PLVL----AIPRRLRVELECEEGELSFYDAERH-CHLYTFHARF--GEVRPYF 464
           P +L      PRR+ V L+ E G +SFY+   H   +YTF   +    + PYF
Sbjct: 420 PSLLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPYF 472


>gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens]
          Length = 516

 Score =  139 bits (351), Expect = 4e-33
 Identities = 125/473 (26%), Positives = 215/473 (45%), Gaps = 34/473 (7%)

Query: 16  KEELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWEVQV-----SPTCPVCKDRASPADLR 70
           +EE+ C +C +   + +++ CGH+FC+ C++      V       +CPVC+    P +LR
Sbjct: 38  REEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQPGNLR 97

Query: 71  TNHTLNNLVEKLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQADPRHQ 130
            N  L N+V +L RE   G        + +C  H  +L LFC ED +++C  C+    H+
Sbjct: 98  PNRHLANIVRRL-REVVLGPG--KQLKAVLCADHGEKLQLFCQEDGKVICWLCERSQEHR 154

Query: 131 GHRVQPVKDTAHDFRAKCRNMEHALR---EKAKAFWAMRRSYEAIAKHNQVEAAWLEGRI 187
           GH    V++ A +++ K +     L+   ++A+   A  R  +   K NQ+E      RI
Sbjct: 155 GHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWK-NQMEPE--RCRI 211

Query: 188 RQEFDKLREFLRVEEQAILDAMAEETRQKQLLADEKMKQLTEETEVLAHEIERLQMEMKE 247
           + EF++LR  L   EQ  L  + +E ++   + +E    L  +T+ L   I  L+   + 
Sbjct: 212 QTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRCQG 271

Query: 248 DDVSFLMKHKS-RKRRLFCTMEPEPVQPGMLIDVCKYLGSLQYRVWKKMLASVES--VPF 304
             +  L       +R  F T+      P  L  + +     +     + L  V+S  V  
Sbjct: 272 STMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYWVDV 331

Query: 305 SFDPNTAAGWLSVSDDLTSVTNHGYRVQVENPERFSSAPCLLGSRVFSQGSHAWEVALGG 364
           + +P+TA   L ++ +   V   G +V   +         +LGS+ FS G H WEV +  
Sbjct: 332 TLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEKHYDCSVLGSQHFSSGKHYWEVDVAK 391

Query: 365 LQSWRVGVV------RVRQDSGAEGHSHSCYHDTRSGFWYVCRTQGVEGDHCVTSDPATS 418
             +W +GV           +  A+ HS    +  +SG+W +    G++ +H   +   +S
Sbjct: 392 KTAWILGVCSNSLGPTFSFNHFAQNHSAYSRYQPQSGYWVI----GLQHNHEYRAYEDSS 447

Query: 419 PLVL----AIPRRLRVELECEEGELSFYDAERH-CHLYTFHARF--GEVRPYF 464
           P +L      PRR+ V L+ E G +SFY+   H   +YTF   +    + PYF
Sbjct: 448 PSLLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPYF 500


>gi|42516572 tripartite motif-containing 41 isoform 1 [Homo sapiens]
          Length = 630

 Score =  137 bits (345), Expect = 2e-32
 Identities = 124/461 (26%), Positives = 194/461 (42%), Gaps = 46/461 (9%)

Query: 56  TCPVCKDRASPADLRTNHTLNNLVEKLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLED 115
           TCP C+        R N  L N+V+ + +      R +      +C  H+  L LFC  D
Sbjct: 182 TCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGICPKHQEALKLFCEVD 241

Query: 116 KELLCCSCQADPRHQGHRVQPVKDTAHDFRAKCRNMEHALREKAKAFWAMRRSYEAIAKH 175
           +E +C  C+    H+ H V P+++   +++AK +     LR+  +A   M+   E     
Sbjct: 242 EEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMKAKEERRVTE 301

Query: 176 NQVEAAWLEGRIRQEFDKLREFLRVEEQAILDAMAEETRQKQL-LADEKMKQLTEETEVL 234
            + +       +  EF +L  FL  EEQA L+    E  + QL  A     +L E+   L
Sbjct: 302 LKSQMKSELAAVASEFGRLTRFL-AEEQAGLERRLREMHEAQLGRAGAAASRLAEQAAQL 360

Query: 235 AHEIERLQMEMKEDDVSFLMKHKSRKRRLFC---------TMEPEPVQPGMLIDVCKYLG 285
           +  +   Q   ++  +  L   K    R  C            P+P QP        +L 
Sbjct: 361 SRLLAEAQERSQQGGLRLLQDIKETFNR--CEEVQLQPPEVWSPDPCQP----HSHDFLT 414

Query: 286 SLQYRVWKKMLASVESVPFSFDPNTAAGWLSVSDDLTSVTNHGYRVQV-ENPERFSSAPC 344
               R   +M      V  + DP+TA   L +S D   V     R +V ++P+RFS+  C
Sbjct: 415 DAIVRKMSRMFCQAARVDLTLDPDTAHPALMLSPDRRGVRLAERRQEVADHPKRFSADCC 474

Query: 345 LLGSRVFSQGSHAWEVALGGLQSWRVGVVRVRQ----------DSGAEGHSHSCYHDTRS 394
           +LG++ F  G H WEV +GG + W VG  R              S   G + S  H  R 
Sbjct: 475 VLGAQGFRSGRHYWEVEVGGRRGWAVGAARESTHHKEKVGPGGSSVGSGDASSSRHHHRR 534

Query: 395 GFWYVCRTQGVEGD-HCV-------TSDPATSPLVLA---IPRRLRVELECEEGELSFYD 443
              ++ +   ++ +  CV        +  +T   +L+    PRR  V L+ E G L FY+
Sbjct: 535 RRLHLPQQPLLQREVWCVGTNGKRYQAQSSTEQTLLSPSEKPRRFGVYLDYEAGRLGFYN 594

Query: 444 AERHCHLYTFHARF-GE-VRPYFYLGGARGAGPPEPLRICP 482
           AE   H++TF A F GE V P+F     R       +++CP
Sbjct: 595 AETLAHVHTFSAAFLGERVFPFF-----RVLSKGTRIKLCP 630



 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 21/43 (48%), Positives = 32/43 (74%)

Query: 7  VSPGPSRSFKEELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCW 49
          ++P P ++ +EE +CA+C D F D V++ CGHNFCR CV++ W
Sbjct: 6  MTPNPVQTLQEEAVCAICLDYFTDPVSIGCGHNFCRVCVTQLW 48


>gi|14670266 tripartite motif protein TRIM4 isoform alpha [Homo
           sapiens]
          Length = 500

 Score =  135 bits (340), Expect = 8e-32
 Identities = 134/505 (26%), Positives = 195/505 (38%), Gaps = 72/505 (14%)

Query: 12  SRSFKEELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWEVQVSP-TCPVCKDRASPADLR 70
           +   +EEL C +C D F+D V++ CGHNFCRGC+ R W     P  CP C+  ++PA LR
Sbjct: 3   AEDIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSAPAALR 62

Query: 71  TNHTLNNLVEKLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQADPRHQ 130
            N  L  L EK  R               +C  H   L LFC +D+  +C  C+    HQ
Sbjct: 63  PNWALARLTEKTQRRRLGPVP------PGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQ 116

Query: 131 GHRVQPVKDTAHDFRA----------KCRNMEHALREKAKAFWAMRRSYEAIAKHNQV-- 178
            H + P+ +    +R           K R +   L    +    ++     +AK  +V  
Sbjct: 117 THAMAPIDEAFESYRTGNFDIHVDEWKRRLIRLLLYHSKQEEKLLKSQRNLVAKMKKVMH 176

Query: 179 --------EAAWLEG------RIRQEFDKLREFLRVEEQAILDAMAEETRQKQLLADEKM 224
                      W +       RI  EF KL  FL  EE   L  + +E        +E  
Sbjct: 177 LQDVEVKNATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKE-------EEETK 229

Query: 225 KQLTEETEVLAHEI---ERLQMEMKEDDVSFLMKHKSRKRRLFCTMEPEPVQPGMLIDVC 281
           K+L E T  L   I   ++L +E+ E   +  ++     + +    E + V     ++  
Sbjct: 230 KKLNENTLKLNQTIASLKKLILEVGEKSQAPTLELLQNPKEVLTRSEIQDV--NYSLEAV 287

Query: 282 KYLGSLQYRVWKKMLASVESVPFSFDPNTAAGWLSVSDDLTSVTN-------------HG 328
           K     Q  + K+ML   + V  +   +TA   L  S +   V N               
Sbjct: 288 KVKTVCQIPLMKEMLKRFQ-VAVNLAEDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWN 346

Query: 329 YRVQVENP------ERFSSAPCLLGSRVFSQGSHAWEVALGGLQSWRVGVVRVRQDSGAE 382
           Y     NP      ERF   PC+LG  VF+ G H WEV         VGV R        
Sbjct: 347 YFAGWRNPQKTAFVERFQHLPCVLGKNVFTSGKHYWEVESRDSLEVAVGVCR----EDVM 402

Query: 383 GHSHSCYHDTRSGFWYVCRTQGVEGDHCVTSDPATSPLVLAIPRRLRVELECEEGELSFY 442
           G +         G W +       G   +   P T         R+ V L+   G +SFY
Sbjct: 403 GITDRSKMSPDVGIWAI--YWSAAGYWPLIGFPGTPTQQEPALHRVGVYLDRGTGNVSFY 460

Query: 443 DAERHCHLYTFH-ARFGEVRPYFYL 466
            A    HL+TF  +    +RP+F+L
Sbjct: 461 SAVDGVHLHTFSCSSVSRLRPFFWL 485


>gi|56605981 tripartite motif-containing 72 [Homo sapiens]
          Length = 477

 Score =  135 bits (339), Expect = 1e-31
 Identities = 128/473 (27%), Positives = 200/473 (42%), Gaps = 54/473 (11%)

Query: 17  EELLCAVCYDPFRDAVTLRCGHNFCRGCVSR-CWEVQVSPT--CPVCKDRASPADLRTNH 73
           +EL C +C   F   VT  CGH+FCR C+ R   E     T  CP C+    P  L TN 
Sbjct: 10  QELSCPLCLQLFDAPVTAECGHSFCRACLGRVAGEPAADGTVLCPCCQAPTRPQALSTNL 69

Query: 74  TLNNLVEKLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQADPRHQGHR 133
            L  LVE  L +  +G           C  H   LS++C +D+ L+C  C +   H+GHR
Sbjct: 70  QLARLVEG-LAQVPQGH----------CEEHLDPLSIYCEQDRALVCGVCASLGSHRGHR 118

Query: 134 VQPVKDTAHDFRAKCRNMEHALREKAKAFWAMRRSYE-AIAKHNQVE----AAWLEGRIR 188
           + P  +     + +    +  L+E       MR+    A+ +H  VE         G + 
Sbjct: 119 LLPAAEAHARLKTQLPQQKLQLQEA-----CMRKEKSVAVLEHQLVEVEETVRQFRGAVG 173

Query: 189 QEFDKLREFLRVEEQAILDAMAEETRQKQLLA-DEKMKQLTEETEVLAHEIERLQMEMKE 247
           ++  K+R FL   E + LD  AE  R +  +A   ++  L    E L    + L+    +
Sbjct: 174 EQLGKMRVFLAALEGS-LDCEAERVRGEAGVALRRELGSLNSYLEQLRQMEKVLEEVADK 232

Query: 248 DDVSFLMKHKSRKRRLFCTMEPEPVQPGMLIDVCKYLGSLQYRVWKKMLASVESV--PFS 305
               FLMK+     RL   +   P    + I +       +++VW+KM  ++       +
Sbjct: 233 PQTEFLMKYCLVTSRLQKILAESPPPARLDIQLPIISDDFKFQVWRKMFRALMPALEELT 292

Query: 306 FDPNTAAGWLSVSDDLTSVTNHGYRVQV---------ENPERFSSAPCLLGSRVFSQGSH 356
           FDP++A   L VS       + G RV+          E+P +F  A  ++  +  S+G H
Sbjct: 293 FDPSSAHPSLVVS-------SSGRRVECSEQKAPPAGEDPRQFDKAVAVVAHQQLSEGEH 345

Query: 357 AWEVALGGLQSWRVGVVRVRQDSGAEGHSHSCYHDTRSGFWYVCRTQG-VEGDHCVTSDP 415
            WEV +G    W +GV+    ++   G  H+       G W +   +G +   H    +P
Sbjct: 346 YWEVDVGDKPRWALGVIAA--EAPRRGRLHAV---PSQGLWLLGLREGKILEAHVEAKEP 400

Query: 416 ATSPLVLAIPRRLRVELECEEGELSFY---DAERHCHLYTFHARFGE-VRPYF 464
                    P R+ + L   +G LSFY   DA+    L+ FH R    V P+F
Sbjct: 401 RALRSPERRPTRIGLYLSFGDGVLSFYDASDADALVPLFAFHERLPRPVYPFF 453


>gi|68160935 tripartite motif-containing 17 isoform 2 [Homo sapiens]
          Length = 450

 Score =  134 bits (336), Expect = 2e-31
 Identities = 121/468 (25%), Positives = 201/468 (42%), Gaps = 69/468 (14%)

Query: 36  CGHNFCRGCVSRCWEV----------QVSPTCPVCKDRASPADLRTNHTLNNLVEKLLRE 85
           CGHNFCR C+   WE           + S  CP C++ +   +L  N  L  + E  + +
Sbjct: 4   CGHNFCRACIQLSWEKARGKKGRRKRKGSFPCPECREMSPQRNLLPNRLLTKVAE--MAQ 61

Query: 86  EAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQADPRHQGHRVQPVKDTAHDFR 145
           +  G +        +C+ H   L LFC +D+  +C  C+    H+ HRV P ++    ++
Sbjct: 62  QHPGLQKQD-----LCQEHHEPLKLFCQKDQSPICVVCRESREHRLHRVLPAEEAVQGYK 116

Query: 146 AKCRNMEHALREKAKAFWAMRRSYEAIAKHNQVEAAWLEGRIRQ-------EFDKLREFL 198
            K       LRE+      + R+    A+  Q  A W +G++++       EF+K+  +L
Sbjct: 117 LKLEEDMEYLREQ------ITRTGNLQAREEQSLAEW-QGKVKERRERIVLEFEKMNLYL 169

Query: 199 RVEEQAILDAMAEETRQKQLLADEKMKQLTEETEVLAHEIERLQMEMKEDDVSFL----- 253
             EEQ +L A+  E  +      E +  L  +     H +E L ++++E           
Sbjct: 170 VEEEQRLLQALETEEEETASRLRESVACLDRQ----GHSLELLLLQLEERSTQGPLQMLQ 225

Query: 254 -MKHKSRKRRLFCTMEPEPVQPGMLIDVCKYLGSLQYRVWKKMLASVESVPFSFDPNTAA 312
            MK    ++       PE   P     VC+  G  Q  V +  L  V  VP   D  +A 
Sbjct: 226 DMKEPLSRKNNVSVQCPEVAPPTRPRTVCRVPG--QIEVLRGFLEDV--VP---DATSAY 278

Query: 313 GWLSVSDDL------TSVTNHGYRVQVENPERFSSAPCLLGSRVFSQGSHAWEVALG--G 364
            +L + +        +S    G+     + +RF + PC +G   FS G H WEV +   G
Sbjct: 279 PYLLLYESRQRRYLGSSPEGSGFC----SKDRFVAYPCAVGQTAFSSGRHYWEVGMNITG 334

Query: 365 LQSWRVGVVRVRQDSGAEGHSHSCYHDTRSGFWYVCRTQGVEGDHCVTSDPATSPLVLAI 424
              W +GV   R +   +     C     +GFW V  ++G +  +  T    T  +++  
Sbjct: 335 DALWALGV--CRDNVSRKDRVPKC---PENGFWVVQLSKGTK--YLSTFSALTPVMLMEP 387

Query: 425 PRRLRVELECEEGELSFYDAERHCHLYTF-HARF-GEVRPYFYLGGAR 470
           P  + + L+ E GE+SFY      HL+T+  A F G ++P+F LG  +
Sbjct: 388 PSHMGIFLDFEAGEVSFYSVSDGSHLHTYSQATFPGPLQPFFCLGAPK 435


>gi|31542779 tripartite motif family-like 1 [Homo sapiens]
          Length = 468

 Score =  131 bits (330), Expect = 1e-30
 Identities = 122/481 (25%), Positives = 203/481 (42%), Gaps = 28/481 (5%)

Query: 14  SFKEELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWEVQVSP-TCPVCKDRASPADLRTN 72
           + +EEL C +C D F   VT  CGH+FC  C+ R WE   +P +CP C         ++N
Sbjct: 9   NLREELTCFICLDYFSSPVTTECGHSFCLVCLLRSWEEHNTPLSCPECWRTLEGPHFQSN 68

Query: 73  HTLNNL--VEKLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQADPRHQ 130
             L  L  + + LR +   +      + R+        +   L D E    +  A   H 
Sbjct: 69  ERLGRLASIARQLRSQVLQSEDEQGSYGRM------PTTAKALSDDEQGGSAFVAQ-SHG 121

Query: 131 GHRVQPVKDTAHDFRAKCRNMEHALREKAKAFWAMRRSYEAIAKHNQVEAAWLEGRIRQE 190
            +RV    +     R K + + + LR + K   A+    +   K  Q E    +  +  E
Sbjct: 122 ANRVHLSSEAEEHHREKLQEILNLLRVRRKEAQAVLTHEKERVKLCQEETKTCKQVVVSE 181

Query: 191 FDKLREFLRVEEQAILDAMAEETRQKQLLADEKMKQLTEETEVLAHEIERLQMEMKEDDV 250
           + K+ +FL+ EEQ  L  + +E ++          +LT++   L+  I +++   +    
Sbjct: 182 YMKMHQFLKEEEQLQLQLLEQEEKENMRKLRNNEIKLTQQIRSLSKMIAQIESSSQSSAF 241

Query: 251 SFLMKHKSRKRRLFCTMEPEPVQPGMLIDVCKYLGSLQYRVWKKMLASVESVPFSFDPNT 310
             L + +    R    +   P      + +C+  G       K+ML    S   + DP T
Sbjct: 242 ESLEEVRGALERSEPLLLQCPEATTTELSLCRITG------MKEMLRKF-STEITLDPAT 294

Query: 311 AAGWLSVSDDLTSVTNHGYRVQV-ENPERFSSAPCLLGSRVFSQGSHAWEVALGGLQSWR 369
           A  +L +S+DL SV   G R Q+ +NPERF  +  +LG+++F+ G H WEV +G    W 
Sbjct: 295 ANAYLVLSEDLKSVKYGGSRQQLPDNPERFDQSATVLGTQIFTSGRHYWEVEVGNKTEWE 354

Query: 370 VGVVRVRQDSGAEGHSHSCYHDTRSGFWYVCRTQGVEGDHCV-TSDPATSPLVLAIPRRL 428
           VG+ +       +  S         G  +      +  D+ +  S P     V     ++
Sbjct: 355 VGICK-------DSVSRKGNLPKPPGDLFSLIGLKIGDDYSLWVSSPLKGQHVREPVCKV 407

Query: 429 RVELECEEGELSFYDAERHCHLYTF-HARFGE-VRPYFYLGGARGAGPPEPLRICPLHIS 486
            V L+ E G ++FY+      +Y+F  A F E +RP F           +PL IC L+  
Sbjct: 408 GVFLDYESGHIAFYNGTDESLIYSFPQASFQEALRPIFSPCLPNEGTNTDPLTICSLNSH 467

Query: 487 V 487
           V
Sbjct: 468 V 468


>gi|20270353 tripartite motif-containing 43 [Homo sapiens]
          Length = 446

 Score =  129 bits (325), Expect = 5e-30
 Identities = 125/482 (25%), Positives = 207/482 (42%), Gaps = 69/482 (14%)

Query: 12  SRSFKEELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWEVQVSP-TCPVCKDRASPADLR 70
           S +F++EL C +C +   D VT+ CGH+FCR C+   WE   SP  CP C++ +   D +
Sbjct: 6   SHAFQKELTCVICLNYLVDPVTICCGHSFCRPCLCLSWEEAQSPANCPACREPSPKMDFK 65

Query: 71  TNHTLNNLVEKLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQADPRHQ 130
           TN  L NLV   +  +A   ++ S    ++C  HR    +FC  DK LLC  C     H 
Sbjct: 66  TNILLKNLV--TIARKASLWQFLSSE-KQICGTHRQTKKMFCDMDKSLLCLLCSNSQEHG 122

Query: 131 GHRVQPVKDTAHDFRAKCRNMEHALREKAKAFWAMRRSYEA-----IAKHNQVEAAWLEG 185
            H+  P+++ A + R K       L +K +     R  YE      + + N V  A +  
Sbjct: 123 AHKHHPIEEAAEEHREKLLKQMRILWKKIQE--NQRNLYEEGRTAFLWRGNVVLRAQM-- 178

Query: 186 RIRQEFDKLREFLRVEEQAILDAMAEE-------TRQKQLLADEKMKQLTEETEVLAHEI 238
            IR E+ KL   L  EE+  L+ + +E        ++  +  D+K K L E  + L    
Sbjct: 179 -IRNEYRKLHPVLHKEEKQHLERLNKEYQEIFQQLQRSWVKMDQKSKHLKEMYQELMEMC 237

Query: 239 ERLQMEMKEDDVSFLMKHKSRKRRLFCTMEPEPVQPGMLIDVCKYLGSLQYRVWKKMLAS 298
            +  +E+ +D    + + +S    +     P+PV P +        G +   V++     
Sbjct: 238 HKPDVELLQDLGDIVARSESVLLHM-----PQPVNPELT------AGPITGLVYRLNRFR 286

Query: 299 VESVPFSFDPNTAAGWLSVSDDLTSVTNHGYRVQVE-----------NPERFSSAPCLLG 347
           VE + F F+                VTNH  R+  +           N +R S      G
Sbjct: 287 VE-ISFHFE----------------VTNHNIRLFEDVRSWMFRRGPLNSDR-SDYFAAWG 328

Query: 348 SRVFSQGSHAWEVALGGLQSWRVGVVRVRQDSGAEGHSHSCYHDTRSGFWYVCRTQGVEG 407
           +RVFS G H WE+ +     W +GV      + +    +S   ++   F  +C  +    
Sbjct: 329 ARVFSFGKHYWELDVDNSCDWALGVC-----NNSWIRKNSTMVNSEDIFLLLC-LKVDNH 382

Query: 408 DHCVTSDPATSPLVLAIPRRLRVELECEEGELSFYDAERHCHLYTFHA--RFGEVRPYFY 465
            + +T+ P     +     R+ V L+ E G +SF +  +   ++++ A      VRP+FY
Sbjct: 383 FNLLTTSPVFPHYIEKPLGRVGVFLDFESGSVSFLNVTKSSLIWSYPAGSLTFPVRPFFY 442

Query: 466 LG 467
            G
Sbjct: 443 TG 444


>gi|88953346 PREDICTED: Tripartite motif-containing protein 43-like
           protein 1 [Homo sapiens]
          Length = 446

 Score =  129 bits (323), Expect = 8e-30
 Identities = 122/481 (25%), Positives = 208/481 (43%), Gaps = 67/481 (13%)

Query: 12  SRSFKEELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWEVQVSP-TCPVCKDRASPADLR 70
           S +F++EL C +C +   D VT+ CGH+FCR C+   WE   SP  CP C++ +   D +
Sbjct: 6   SHAFQKELTCVICLNYLVDPVTICCGHSFCRPCLCLSWEEAQSPANCPACREPSPKMDFK 65

Query: 71  TNHTLNNLVEKLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQADPRHQ 130
           TN  L NLV   +  +A   ++ S    ++C  HR    +FC  DK LLC  C     H 
Sbjct: 66  TNILLKNLV--TIARKASLWQFLSSE-KQICGTHRQTKKMFCDMDKSLLCLLCSNSQEHG 122

Query: 131 GHRVQPVKDTAHDFRAK----CRNMEHALREKAKAFWAMRRSYEAIAKHNQVEAAWLEGR 186
            H+  P+++ A + R K     R +   ++E  +  +  RR+   +     + A      
Sbjct: 123 AHKHYPIEEAAEEDREKLLKQMRILWKKIQENQRNLYEERRTAFLLRGDVVLRAQ----M 178

Query: 187 IRQEFDKLREFLRVEEQAILDAMAEE-------TRQKQLLADEKMKQLTEETEVLAHEIE 239
           IR E+ KL   L  EE+  L+ + +E        ++  +  D+K K L E  + L     
Sbjct: 179 IRNEYRKLHPVLHKEEKQHLERLNKEYQEIFQQLQRSWVKMDQKSKHLKEMYQELMEMCH 238

Query: 240 RLQMEMKEDDVSFLMKHKSRKRRLFCTMEPEPVQPGMLIDVCKYLGSLQYRVWKKMLASV 299
           + ++E+ +D    + + +S    +     P+PV P +        G +   V++     V
Sbjct: 239 KPEVELLQDLGDIVARSESVLLHM-----PQPVNPELT------AGPITGLVYRLNRFRV 287

Query: 300 ESVPFSFDPNTAAGWLSVSDDLTSVTNHGYRVQVE-----------NPERFSSAPCLLGS 348
           E + F F+                VTNH  R+  +           N +R S      G+
Sbjct: 288 E-ISFHFE----------------VTNHNIRLFEDVRSWMFRRGPLNSDR-SDYFAAWGA 329

Query: 349 RVFSQGSHAWEVALGGLQSWRVGVVRVRQDSGAEGHSHSCYHDTRSGFWYVCRTQGVEGD 408
           RVFS G H WE+ +     W +GV      + +    +S   ++   F  +C  +     
Sbjct: 330 RVFSFGKHYWELDVDNSCDWALGVC-----NNSWIRKNSTMVNSEDIFLLLC-LKVDNHF 383

Query: 409 HCVTSDPATSPLVLAIPRRLRVELECEEGELSFYDAERHCHLYTFHA--RFGEVRPYFYL 466
           + +T+ P     +     R+ V L+ E G +SF +  +   ++++ A      VRP+FY 
Sbjct: 384 NLLTTSPVFPHYIEKPLGRVGVFLDFESGSVSFLNVTKSSLIWSYPAGSLTFPVRPFFYT 443

Query: 467 G 467
           G
Sbjct: 444 G 444


>gi|157426896 tripartite motif-containing 10 isoform 2 [Homo
           sapiens]
          Length = 395

 Score =  127 bits (320), Expect = 2e-29
 Identities = 107/394 (27%), Positives = 174/394 (44%), Gaps = 51/394 (12%)

Query: 14  SFKEELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWEV-----QVSPTCPVCKDRASPAD 68
           S  +E+ C +C    R+ VT+ CGHNFCR C++R  E+     + SPTCP+CK+   P  
Sbjct: 9   SLADEVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLCKEPFRPGS 68

Query: 69  LRTNHTLNNLVEKLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQADPR 128
            R N  L N+VE +  E  +           VC+ H  ++  FC +D+  LC  C+    
Sbjct: 69  FRPNWQLANVVENI--ERLQLVSTLGLGEEDVCQEHGEKIYFFCEDDEMQLCVVCREAGE 126

Query: 129 HQGHRVQPVKDTAHDFRAKCRNMEHALREKAKAFWAMRRSYEAIAKHNQVEAAWLEGRIR 188
           H  H ++ ++D A  +R +       LR++ +    ++       +    + +    ++ 
Sbjct: 127 HATHTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQSRENKRMQVLLTQVSTKRQQVI 186

Query: 189 QEFDKLREFLRVEEQAILDAMAEE-----TRQK---QLLADEKMKQLTEETEVLAHEIER 240
            EF  LR+FL  E+Q+IL A  E       RQ+    LL   ++ + +   E L  + ER
Sbjct: 187 SEFAHLRKFLE-EQQSILLAQLESQDGDILRQRDEFDLLVAGEICRFSALIEELEEKNER 245

Query: 241 LQMEMKEDDVSFLMKHKSRKRRLFCTMEPE-------------PVQPGMLIDVCKYLGSL 287
              E+  D  S L++ ++RK R    + PE             P+Q  M + + K    L
Sbjct: 246 PARELLTDIRSTLIRCETRKCRKPVAVSPELGQRIRDFPQQALPLQREMKMFLEKLCFEL 305

Query: 288 QYRVWKKMLASVESVPFSFDPNTAAGWLSVSDD-LTSVTNHGYRVQVENPERFSSAPCLL 346
            Y          E    S DP T+   L +S+D   +  ++ ++   +NP+RF  A C+L
Sbjct: 306 DY----------EPAHISLDPQTSHPKLLLSEDHQRAQFSYKWQNSPDNPQRFDRATCVL 355

Query: 347 GSRVFSQGSHAWEVALGGLQSWRVGVVRVRQDSG 380
                + G H W           V + RV  DSG
Sbjct: 356 AHTGITGGRHTW-----------VWMARVPGDSG 378


>gi|117938316 tripartite motif-containing 22 [Homo sapiens]
          Length = 498

 Score =  127 bits (318), Expect = 3e-29
 Identities = 135/512 (26%), Positives = 218/512 (42%), Gaps = 102/512 (19%)

Query: 16  KEELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWEVQV-----SPTCPVCKDRASPADLR 70
           ++E+ C +C +   + ++L CGH+FC+ C++   +  V       +CPVC+ R  P +LR
Sbjct: 10  EKEVTCPICLELLTEPLSLDCGHSFCQACITAKIKESVIISRGESSCPVCQTRFQPGNLR 69

Query: 71  TNHTLNNLVEKLLREEA---EGARWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQADP 127
            N  L N+VE++   +    EG +        VC  H  +L +FC ED +++C  C+   
Sbjct: 70  PNRHLANIVERVKEVKMSPQEGQK------RDVCEHHGKKLQIFCKEDGKVICWVCELSQ 123

Query: 128 RHQGHRVQPVKDTAHDFRAKCRNMEHALREKAKAFWAMRRSYEAIAKHNQVEAAWLEGRI 187
            HQGH+   + +   + + K                 ++ + + + K +Q EA  LE  I
Sbjct: 124 EHQGHQTFRINEVVKECQEK-----------------LQVALQRLIKEDQ-EAEKLEDDI 165

Query: 188 RQEFDKLREFLRVEEQAILDAM--------AEETRQKQLL-------------ADEKMKQ 226
           RQE    + ++++E Q IL            EE R+ Q L             A +++ Q
Sbjct: 166 RQERTAWKNYIQIERQKILKGFNEMRVILDNEEQRELQKLEEGEVNVLDNLAAATDQLVQ 225

Query: 227 LTEETEVLAHEIER----LQMEMKEDDVSF--------LMKHKSRKRRLFCTMEPEPVQP 274
             ++   L  +++R      +EM +D +          L K KS  ++L       P   
Sbjct: 226 QRQDASTLISDLQRRLRGSSVEMLQDVIDVMKRSESWTLKKPKSVSKKLKSVFR-VPDLS 284

Query: 275 GMLIDVCKYLGSLQYRVWKKMLASVESVPFSFDPNTAAGWLSVSDDLTSV-TNHGYRVQV 333
           GML  V K L  +QY  W         V    +P +A   +++S D   V T      + 
Sbjct: 285 GML-QVLKELTDVQY-YW---------VDVMLNPGSATSNVAISVDQRQVKTVRTCTFKN 333

Query: 334 ENPERFSSAPCLLGSRVFSQGSHAWEVALGGLQSWRVGV------VRVRQDSGAEGHSHS 387
            NP  F SA  + G + FS G + WEV + G  +W +GV      +  R+ SG       
Sbjct: 334 SNPCDF-SAFGVFGCQYFSSGKYYWEVDVSGKIAWILGVHSKISSLNKRKSSGFAFDPSV 392

Query: 388 CYHDTRS------GFWYV-----CRTQGVEGDHCVTSDPATSPLVLAIPR-RLRVELECE 435
            Y    S      G+W +     C     E     +SDP    L +A+P  R+ V L+ E
Sbjct: 393 NYSKVYSRYRPQYGYWVIGLQNTCEYNAFEDSS--SSDPKVLTLFMAVPPCRIGVFLDYE 450

Query: 436 EGELSFYDAERH-CHLYTFH-ARFGE-VRPYF 464
            G +SF++   H   +Y F   RF     PYF
Sbjct: 451 AGIVSFFNVTNHGALIYKFSGCRFSRPAYPYF 482


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.135    0.431 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,109,279
Number of Sequences: 37866
Number of extensions: 982991
Number of successful extensions: 4656
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 239
Number of HSP's successfully gapped in prelim test: 337
Number of HSP's that attempted gapping in prelim test: 3503
Number of HSP's gapped (non-prelim): 1075
length of query: 493
length of database: 18,247,518
effective HSP length: 106
effective length of query: 387
effective length of database: 14,233,722
effective search space: 5508450414
effective search space used: 5508450414
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.