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Search of human proteins with 93277115
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|93277115 ataxin 7-like 2 [Homo sapiens]
(722 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|93277115 ataxin 7-like 2 [Homo sapiens] 1494 0.0
gi|163937854 ataxin 7-like 1 isoform 1 [Homo sapiens] 333 3e-91
gi|189491742 ataxin 7 isoform b [Homo sapiens] 263 3e-70
gi|4506797 ataxin 7 isoform a [Homo sapiens] 263 3e-70
gi|211971080 ataxin 7-like 1 isoform 3 [Homo sapiens] 217 3e-56
gi|23308753 ataxin 7-like 1 isoform 2 [Homo sapiens] 117 4e-26
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 55 2e-07
gi|110832843 TBP-associated factor 4 [Homo sapiens] 55 3e-07
gi|163965366 nascent polypeptide-associated complex alpha subuni... 52 1e-06
gi|55750053 atrophin-1 [Homo sapiens] 51 4e-06
gi|55750041 atrophin-1 [Homo sapiens] 51 4e-06
gi|34878787 ring finger protein 25 [Homo sapiens] 48 4e-05
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 46 1e-04
gi|223972704 hypothetical protein LOC284418 [Homo sapiens] 45 2e-04
gi|33946327 nucleoporin 214kDa [Homo sapiens] 44 4e-04
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 44 4e-04
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 44 4e-04
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 44 4e-04
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 44 4e-04
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 44 4e-04
gi|42544125 splicing factor 1 isoform 2 [Homo sapiens] 44 4e-04
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 44 5e-04
gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 44 5e-04
gi|50345997 E1A binding protein p300 [Homo sapiens] 44 7e-04
gi|42544130 splicing factor 1 isoform 1 [Homo sapiens] 43 9e-04
gi|110611908 mitogen-activated protein kinase kinase kinase kina... 43 0.001
gi|6005810 mitogen-activated protein kinase kinase kinase kinase... 43 0.001
gi|210032580 SET domain containing 1B [Homo sapiens] 43 0.001
gi|24497538 homeobox C4 [Homo sapiens] 42 0.002
gi|24497540 homeobox C4 [Homo sapiens] 42 0.002
>gi|93277115 ataxin 7-like 2 [Homo sapiens]
Length = 722
Score = 1494 bits (3867), Expect = 0.0
Identities = 722/722 (100%), Positives = 722/722 (100%)
Query: 1 MAVRERAAAAMAALERRVPSLDDFAGQSWSSWVERADLPAADGAELEESSKNTKKLDAMT 60
MAVRERAAAAMAALERRVPSLDDFAGQSWSSWVERADLPAADGAELEESSKNTKKLDAMT
Sbjct: 1 MAVRERAAAAMAALERRVPSLDDFAGQSWSSWVERADLPAADGAELEESSKNTKKLDAMT 60
Query: 61 LIKEDMSIFGHCPAHDDFYLVVCNHCSQVVKPQAFQKHCERRHGPLSKLYGRAPPPPPAP 120
LIKEDMSIFGHCPAHDDFYLVVCNHCSQVVKPQAFQKHCERRHGPLSKLYGRAPPPPPAP
Sbjct: 61 LIKEDMSIFGHCPAHDDFYLVVCNHCSQVVKPQAFQKHCERRHGPLSKLYGRAPPPPPAP 120
Query: 121 ASSQKCHVVNGQGPACRAPGSTKTSSREKGQGSRSRGHQPPEKTQKDNLCQPGGLTKDSP 180
ASSQKCHVVNGQGPACRAPGSTKTSSREKGQGSRSRGHQPPEKTQKDNLCQPGGLTKDSP
Sbjct: 121 ASSQKCHVVNGQGPACRAPGSTKTSSREKGQGSRSRGHQPPEKTQKDNLCQPGGLTKDSP 180
Query: 181 GKPPMAPPSKEPPGRENIEIIPSEGSSHWAEGSPPEKEPSGTRLPPKTHRKMARKECDLN 240
GKPPMAPPSKEPPGRENIEIIPSEGSSHWAEGSPPEKEPSGTRLPPKTHRKMARKECDLN
Sbjct: 181 GKPPMAPPSKEPPGRENIEIIPSEGSSHWAEGSPPEKEPSGTRLPPKTHRKMARKECDLN 240
Query: 241 RQCGVINPETKKICTRLLTCKIHSVHQRREVQGRAKDFDVLVAELKANSRKGESPKEKSP 300
RQCGVINPETKKICTRLLTCKIHSVHQRREVQGRAKDFDVLVAELKANSRKGESPKEKSP
Sbjct: 241 RQCGVINPETKKICTRLLTCKIHSVHQRREVQGRAKDFDVLVAELKANSRKGESPKEKSP 300
Query: 301 GRKEQVLERPSQELPSSVQVVAAVAAPSSTFSVRAKQTYPYCALPRSRASSESELDDEGP 360
GRKEQVLERPSQELPSSVQVVAAVAAPSSTFSVRAKQTYPYCALPRSRASSESELDDEGP
Sbjct: 301 GRKEQVLERPSQELPSSVQVVAAVAAPSSTFSVRAKQTYPYCALPRSRASSESELDDEGP 360
Query: 361 CGGDGDPGLFPFPMPRGGTQASSEESEEEGTSDDLHPPPDCHYATRPPRPQAFCTFGSRL 420
CGGDGDPGLFPFPMPRGGTQASSEESEEEGTSDDLHPPPDCHYATRPPRPQAFCTFGSRL
Sbjct: 361 CGGDGDPGLFPFPMPRGGTQASSEESEEEGTSDDLHPPPDCHYATRPPRPQAFCTFGSRL 420
Query: 421 VSPGCYVFSRRLDRFCSALSSMLERHLSTHMWKKIPPAAEPPAHLVNSPLSAPLSPSSTG 480
VSPGCYVFSRRLDRFCSALSSMLERHLSTHMWKKIPPAAEPPAHLVNSPLSAPLSPSSTG
Sbjct: 421 VSPGCYVFSRRLDRFCSALSSMLERHLSTHMWKKIPPAAEPPAHLVNSPLSAPLSPSSTG 480
Query: 481 TCPRLPGPTLRPACPASMPPTKDNLVPSYPAGSPSVAAACSQAECMGGSQAITSPLPANT 540
TCPRLPGPTLRPACPASMPPTKDNLVPSYPAGSPSVAAACSQAECMGGSQAITSPLPANT
Sbjct: 481 TCPRLPGPTLRPACPASMPPTKDNLVPSYPAGSPSVAAACSQAECMGGSQAITSPLPANT 540
Query: 541 PSPSFSKLPPSKASKSSKGKDGVEVEAPSRKRKLSPGPTTLKRTCILEPTGKGKPSGCRG 600
PSPSFSKLPPSKASKSSKGKDGVEVEAPSRKRKLSPGPTTLKRTCILEPTGKGKPSGCRG
Sbjct: 541 PSPSFSKLPPSKASKSSKGKDGVEVEAPSRKRKLSPGPTTLKRTCILEPTGKGKPSGCRG 600
Query: 601 LSAKTKTALSMGLNGTMGPRVKRAGPLDCRGSPHQLPTPVKASQLENRGAAGHPAKALPT 660
LSAKTKTALSMGLNGTMGPRVKRAGPLDCRGSPHQLPTPVKASQLENRGAAGHPAKALPT
Sbjct: 601 LSAKTKTALSMGLNGTMGPRVKRAGPLDCRGSPHQLPTPVKASQLENRGAAGHPAKALPT 660
Query: 661 NCLSEEEVAKKRKNLATYCRPVKAKHCQAGAPADVACSVRRKKPGPALAFEEKCSTLKSK 720
NCLSEEEVAKKRKNLATYCRPVKAKHCQAGAPADVACSVRRKKPGPALAFEEKCSTLKSK
Sbjct: 661 NCLSEEEVAKKRKNLATYCRPVKAKHCQAGAPADVACSVRRKKPGPALAFEEKCSTLKSK 720
Query: 721 AH 722
AH
Sbjct: 721 AH 722
>gi|163937854 ataxin 7-like 1 isoform 1 [Homo sapiens]
Length = 861
Score = 333 bits (854), Expect = 3e-91
Identities = 269/820 (32%), Positives = 375/820 (45%), Gaps = 144/820 (17%)
Query: 4 RERAAAAMAALERRVPSLDDFAGQSWSSWVERADLPAADGAELEESSKNT-KKLDAMTLI 62
+++ AMA L+R+VPS + F G+ WSSW++ A L +D +LEE+ K K + M L
Sbjct: 22 KQQEGRAMATLDRKVPSPEAFLGKPWSSWIDAAKLHCSDNVDLEEAGKEGGKSREVMRLN 81
Query: 63 KEDMSIFGHCPAHDDFYLVVCNHCSQVVKPQAFQKHCERRHGPLSKLYGRAPPPPPAPAS 122
KEDM +FGH PAHDDFYLVVC+ C+QVVKPQ FQ HCERRHG + R P P +PAS
Sbjct: 82 KEDMHLFGHYPAHDDFYLVVCSACNQVVKPQVFQSHCERRHGSMC----RPSPSPVSPAS 137
Query: 123 SQKCHVVNGQGPACRAPGSTKTSSREKGQGSRSRGHQPPEKTQKDNLCQ---------PG 173
+ + +V + AC + G SS K P KT KDNL P
Sbjct: 138 NPRTSLVQVKTKACLS-GHHSASSTSK-----------PFKTPKDNLLTSSSKQHTVFPA 185
Query: 174 GLTKDSPGKP-PMAPPSKEP----PGRENIEI-------IPSEGSSHWAEGSPP------ 215
++D P P P+ K P N+++ + + +S A +PP
Sbjct: 186 KGSRDKPCVPVPVVSLEKIPNLVKADGANVKMNSTTTTAVSASSTSSSAVSTPPLIKPVL 245
Query: 216 ------------------------EKEPSGTRLPPKTHRKMARKECDLNRQCGVINPETK 251
+K +GT+ K +R+++ +E D N+ CGV++PETK
Sbjct: 246 MSKSVPPSPEKILNGKGILPTTIDKKHQNGTKNSNKPYRRLSEREFDPNKHCGVLDPETK 305
Query: 252 KICTRLLTCKIHSVHQRREVQGRAKDFDVLVAELKANSRKGE-SPKEKSPGRKEQVLERP 310
K CTR LTCK HS+ RR V GR K FD+L+AE KA SR+ E KE ++L
Sbjct: 306 KPCTRSLTCKTHSLSHRRAVPGRKKQFDLLLAEHKAKSREKEVKDKEHLLTSTREILPSQ 365
Query: 311 SQELPSSVQVVAAVAAPSSTFSVRAKQTYPYCALPR-SRASSESELDDEGPCGGDGDPGL 369
S S+ + + P + AK P LPR S A+S S G +P
Sbjct: 366 SGPAQDSLLGSSGSSGPEPKVASPAKSRPPNSVLPRPSSANSISSSTSSNHSGHTPEP-- 423
Query: 370 FPFPMPRGGTQASSEESEEEGTSD--DLHPPPDCHYATRPPRPQAFCTFGSRLVSPGCYV 427
P+P G +S S +EG D D DC ++T PRP AFC+FGSRL+ G YV
Sbjct: 424 ---PLPPVGGDLASRLSSDEGEMDGADESEKLDCQFSTHHPRPLAFCSFGSRLMGRGYYV 480
Query: 428 FSRRLDRFCSALSSMLERHLSTHMWKKIPPAAE-----PPAHLVNSPLSAPLSPSSTGTC 482
F RR DRF AL+SM+E+HL++ MWKKIPPAA+ P AH+ ++ L P S +
Sbjct: 481 FDRRWDRFRFALNSMVEKHLNSQMWKKIPPAADSPLPSPAAHITTPVPASVLQPFSNPSA 540
Query: 483 PRLPGPTLRPACPASMPPTKDNL-------------VPSYPAGSPSVAAACSQAECMGGS 529
LP + +S T L + S+ P VAA S + +
Sbjct: 541 VYLPSAPISSRLTSSYIMTSAMLSNAAFVTSPDPSALMSHTTAFPHVAATLSIMDSTFKA 600
Query: 530 QAITSPLPANTPSPSFSKLPPSKASKSSKGKD--GVEVEAPSRKRKLSPGPTTL------ 581
+ SP+PA PSPS K +K SKSSK KD E+PS K++ T+
Sbjct: 601 PSAVSPIPAVIPSPS-HKPSKTKTSKSSKVKDLSTRSDESPSNKKRKPQSSTSSSSSSSS 659
Query: 582 ---------------KRTCILEPTG----------------KGKPSGCRGLSAKTKTALS 610
K+ C+L + +G LSAK + +
Sbjct: 660 SSLQTSLSSPLSGPHKKNCVLNASSALNSYQAAPPYNSLSVHNSNNGVSPLSAKLEPSGR 719
Query: 611 MGLNGTMGPRVKRAGPLDCRGSPHQLPTPVKASQLENRGAAGHPA-KALPTNCLSEEEVA 669
L G V++ G + L P A + A H A +LP + ++
Sbjct: 720 TSLPGGPADIVRQVGAVGGSSDSCPLSVPSLALHAGDLSLASHNAVSSLPLS--FDKSEG 777
Query: 670 KKRKNLATYCRPVKAKHCQAGAPADVACSVRRKKPGPALA 709
KKRKN ++ +K C+ + SV +K P LA
Sbjct: 778 KKRKNSSS-----SSKACKITKMPGMN-SVHKKNPPSLLA 811
>gi|189491742 ataxin 7 isoform b [Homo sapiens]
Length = 945
Score = 263 bits (673), Expect = 3e-70
Identities = 237/753 (31%), Positives = 324/753 (43%), Gaps = 116/753 (15%)
Query: 7 AAAAMAAL-ERR-VPSLDDFAGQSWSSWVERADLPAADGAELEESSKNT-KKLDAMTLIK 63
+AAAMA + ERR +PS + GQSW+ WVE + LP DG EL+ES K K + M L +
Sbjct: 71 SAAAMATVGERRPLPSPEVMLGQSWNLWVEASKLPGKDGTELDESFKEFGKNREVMGLCR 130
Query: 64 EDMSIFGHCPAHDDFYLVVCNHCSQVVKPQAFQKHCERRHGPLSKLYGRAPPPPPAPASS 123
EDM IFG CPAHDDFYLVVCN C+QVVKPQAFQ H ERRH SK PP P S
Sbjct: 131 EDMPIFGFCPAHDDFYLVVCNDCNQVVKPQAFQSHYERRHSSSSK-----PPLAVPPTSV 185
Query: 124 QKCHVVNGQGPACRAPGSTKTSS-----------------REKGQ--GSRSRGHQ----- 159
+ A GS ++SS +EK Q G+ H
Sbjct: 186 FSFFPSLSKSKGGSASGSNRSSSGGVLSASSSSSKLLKSPKEKLQLRGNTRPMHPIQQSR 245
Query: 160 --------PPEKTQKDNLCQPGGLTKDSPGKP-PMAPPSKEPPGRENIEI----IPSEGS 206
P K +K + G L K + G P S PG I +PS G
Sbjct: 246 VPHGRIMTPSVKVEKIHPKMDGTLLKSAVGPTCPATVSSLVKPGLNCPSIPKPTLPSPGQ 305
Query: 207 SHWAEGSPP----EKEPSGTRLPPK-THRKMARKECDLNRQCGVINPETKKICTRLLTCK 261
+G P EK+P K +++++ +E D + CGVI+ +TKK CTR LTCK
Sbjct: 306 ILNGKGLPAPPTLEKKPEDNSNNRKFLNKRLSEREFDPDIHCGVIDLDTKKPCTRSLTCK 365
Query: 262 IHSVHQRREVQGRAKDFDVLVAELKANSRKGESPKEKSPGRKEQVLERPSQELPSSVQVV 321
HS+ QRR VQGR K FDVL+AE K +R+ E + + Q L P P + Q
Sbjct: 366 THSLTQRRAVQGRRKRFDVLLAEHKNKTREKELIRHPDSQQPPQPLRDPHPAPPRTSQ-- 423
Query: 322 AAVAAPSSTFSVRAKQTYPYCALPRSRASSESELDDEGPCGGDGDPGLFPFPM------P 375
+ V ++ P+ A + P G + P P+ P
Sbjct: 424 ---EPHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGCPAQQGGSAPIDPPPVHESPHPP 480
Query: 376 RGGTQASSEESEEEGTSDDLHPPP---DCHYATRPPRPQAFCTFGSRLVSPGCYVFSRRL 432
T+ +S S EEG DD DCHY+ P+P +FCTFGSR + G YVF R
Sbjct: 481 LPATEPASRLSSEEGEGDDKEESVEKLDCHYSGHHPQPASFCTFGSRQIGRGYYVFDSRW 540
Query: 433 DRFCSALSSMLERHLSTHMWKKIPPAAEPPA-------HLVNS-PLS----APLSPSSTG 480
+R AL+ M+E+HL+ +WKKIPP + H NS P S + L+ ++
Sbjct: 541 NRLRCALNLMVEKHLNAQLWKKIPPVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVS 600
Query: 481 TCPRLPGPTLRPACPASMPPTKDNLVPSYPAGSPSVAAACSQAECMGGSQAITSPLPANT 540
T P L T S+ P + + PA S ++ CS M Q +S +T
Sbjct: 601 TSPVLLSSTCISPNSKSV-PAHGTTLNAQPAASGAMDPVCS----MQSRQVSSSSSSPST 655
Query: 541 PSPSFSKLPPSKASKSSKGKDGVEVEAPSRKRKLSPGPTTLKRTCILEP-TGKGKPSGCR 599
PS S +P S S+ P LK + L P G + C+
Sbjct: 656 PS-GLSSVPSSPMSRK---------------------PQKLKSSKSLRPKESSGNSTNCQ 693
Query: 600 GLSAKTKTALSMGLNGTMGPRVKRAGPLDCRGSPHQLPTPVKASQLEN--RGAAGHPAKA 657
S+ T +G G + K + PL S + + +E+ + H
Sbjct: 694 NASSST--------SGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVAHSGPP 745
Query: 658 LPTNCLSEEEVAKKRKNLATYCRPVKAKHCQAG 690
P+ S + + V +H Q+G
Sbjct: 746 YPSTVTSSHSIG--LNCVTNKANAVNVRHDQSG 776
>gi|4506797 ataxin 7 isoform a [Homo sapiens]
Length = 892
Score = 263 bits (673), Expect = 3e-70
Identities = 237/753 (31%), Positives = 324/753 (43%), Gaps = 116/753 (15%)
Query: 7 AAAAMAAL-ERR-VPSLDDFAGQSWSSWVERADLPAADGAELEESSKNT-KKLDAMTLIK 63
+AAAMA + ERR +PS + GQSW+ WVE + LP DG EL+ES K K + M L +
Sbjct: 71 SAAAMATVGERRPLPSPEVMLGQSWNLWVEASKLPGKDGTELDESFKEFGKNREVMGLCR 130
Query: 64 EDMSIFGHCPAHDDFYLVVCNHCSQVVKPQAFQKHCERRHGPLSKLYGRAPPPPPAPASS 123
EDM IFG CPAHDDFYLVVCN C+QVVKPQAFQ H ERRH SK PP P S
Sbjct: 131 EDMPIFGFCPAHDDFYLVVCNDCNQVVKPQAFQSHYERRHSSSSK-----PPLAVPPTSV 185
Query: 124 QKCHVVNGQGPACRAPGSTKTSS-----------------REKGQ--GSRSRGHQ----- 159
+ A GS ++SS +EK Q G+ H
Sbjct: 186 FSFFPSLSKSKGGSASGSNRSSSGGVLSASSSSSKLLKSPKEKLQLRGNTRPMHPIQQSR 245
Query: 160 --------PPEKTQKDNLCQPGGLTKDSPGKP-PMAPPSKEPPGRENIEI----IPSEGS 206
P K +K + G L K + G P S PG I +PS G
Sbjct: 246 VPHGRIMTPSVKVEKIHPKMDGTLLKSAVGPTCPATVSSLVKPGLNCPSIPKPTLPSPGQ 305
Query: 207 SHWAEGSPP----EKEPSGTRLPPK-THRKMARKECDLNRQCGVINPETKKICTRLLTCK 261
+G P EK+P K +++++ +E D + CGVI+ +TKK CTR LTCK
Sbjct: 306 ILNGKGLPAPPTLEKKPEDNSNNRKFLNKRLSEREFDPDIHCGVIDLDTKKPCTRSLTCK 365
Query: 262 IHSVHQRREVQGRAKDFDVLVAELKANSRKGESPKEKSPGRKEQVLERPSQELPSSVQVV 321
HS+ QRR VQGR K FDVL+AE K +R+ E + + Q L P P + Q
Sbjct: 366 THSLTQRRAVQGRRKRFDVLLAEHKNKTREKELIRHPDSQQPPQPLRDPHPAPPRTSQ-- 423
Query: 322 AAVAAPSSTFSVRAKQTYPYCALPRSRASSESELDDEGPCGGDGDPGLFPFPM------P 375
+ V ++ P+ A + P G + P P+ P
Sbjct: 424 ---EPHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGCPAQQGGSAPIDPPPVHESPHPP 480
Query: 376 RGGTQASSEESEEEGTSDDLHPPP---DCHYATRPPRPQAFCTFGSRLVSPGCYVFSRRL 432
T+ +S S EEG DD DCHY+ P+P +FCTFGSR + G YVF R
Sbjct: 481 LPATEPASRLSSEEGEGDDKEESVEKLDCHYSGHHPQPASFCTFGSRQIGRGYYVFDSRW 540
Query: 433 DRFCSALSSMLERHLSTHMWKKIPPAAEPPA-------HLVNS-PLS----APLSPSSTG 480
+R AL+ M+E+HL+ +WKKIPP + H NS P S + L+ ++
Sbjct: 541 NRLRCALNLMVEKHLNAQLWKKIPPVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVS 600
Query: 481 TCPRLPGPTLRPACPASMPPTKDNLVPSYPAGSPSVAAACSQAECMGGSQAITSPLPANT 540
T P L T S+ P + + PA S ++ CS M Q +S +T
Sbjct: 601 TSPVLLSSTCISPNSKSV-PAHGTTLNAQPAASGAMDPVCS----MQSRQVSSSSSSPST 655
Query: 541 PSPSFSKLPPSKASKSSKGKDGVEVEAPSRKRKLSPGPTTLKRTCILEP-TGKGKPSGCR 599
PS S +P S S+ P LK + L P G + C+
Sbjct: 656 PS-GLSSVPSSPMSRK---------------------PQKLKSSKSLRPKESSGNSTNCQ 693
Query: 600 GLSAKTKTALSMGLNGTMGPRVKRAGPLDCRGSPHQLPTPVKASQLEN--RGAAGHPAKA 657
S+ T +G G + K + PL S + + +E+ + H
Sbjct: 694 NASSST--------SGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVAHSGPP 745
Query: 658 LPTNCLSEEEVAKKRKNLATYCRPVKAKHCQAG 690
P+ S + + V +H Q+G
Sbjct: 746 YPSTVTSSHSIG--LNCVTNKANAVNVRHDQSG 776
>gi|211971080 ataxin 7-like 1 isoform 3 [Homo sapiens]
Length = 738
Score = 217 bits (552), Expect = 3e-56
Identities = 211/711 (29%), Positives = 300/711 (42%), Gaps = 139/711 (19%)
Query: 112 RAPPPPPAPASSQKCHVVNGQGPACRAPGSTKTSSREKGQGSRSRGHQPPEKTQKDNLCQ 171
R P P +PAS+ + +V + AC + G SS K P KT KDNL
Sbjct: 3 RPSPSPVSPASNPRTSLVQVKTKACLS-GHHSASSTSK-----------PFKTPKDNLLT 50
Query: 172 ---------PGGLTKDSPGKP-PMAPPSKEP----PGRENIEI-------IPSEGSSHWA 210
P ++D P P P+ K P N+++ + + +S A
Sbjct: 51 SSSKQHTVFPAKGSRDKPCVPVPVVSLEKIPNLVKADGANVKMNSTTTTAVSASSTSSSA 110
Query: 211 EGSPP------------------------------EKEPSGTRLPPKTHRKMARKECDLN 240
+PP +K +GT+ K +R+++ +E D N
Sbjct: 111 VSTPPLIKPVLMSKSVPPSPEKILNGKGILPTTIDKKHQNGTKNSNKPYRRLSEREFDPN 170
Query: 241 RQCGVINPETKKICTRLLTCKIHSVHQRREVQGRAKDFDVLVAELKANSRKGE-SPKEKS 299
+ CGV++PETKK CTR LTCK HS+ RR V GR K FD+L+AE KA SR+ E KE
Sbjct: 171 KHCGVLDPETKKPCTRSLTCKTHSLSHRRAVPGRKKQFDLLLAEHKAKSREKEVKDKEHL 230
Query: 300 PGRKEQVLERPSQELPSSVQVVAAVAAPSSTFSVRAKQTYPYCALPR-SRASSESELDDE 358
++L S S+ + + P + AK P LPR S A+S S
Sbjct: 231 LTSTREILPSQSGPAQDSLLGSSGSSGPEPKVASPAKSRPPNSVLPRPSSANSISSSTSS 290
Query: 359 GPCGGDGDPGLFPFPMPRGGTQASSEESEEEGTSD--DLHPPPDCHYATRPPRPQAFCTF 416
G +P P+P G +S S +EG D D DC ++T PRP AFC+F
Sbjct: 291 NHSGHTPEP-----PLPPVGGDLASRLSSDEGEMDGADESEKLDCQFSTHHPRPLAFCSF 345
Query: 417 GSRLVSPGCYVFSRRLDRFCSALSSMLERHLSTHMWKKIPPAAE-----PPAHLVNSPLS 471
GSRL+ G YVF RR DRF AL+SM+E+HL++ MWKKIPPAA+ P AH+ +
Sbjct: 346 GSRLMGRGYYVFDRRWDRFRFALNSMVEKHLNSQMWKKIPPAADSPLPSPAAHITTPVPA 405
Query: 472 APLSPSSTGTCPRLPGPTLRPACPASMPPTKDNL-------------VPSYPAGSPSVAA 518
+ L P S + LP + +S T L + S+ P VAA
Sbjct: 406 SVLQPFSNPSAVYLPSAPISSRLTSSYIMTSAMLSNAAFVTSPDPSALMSHTTAFPHVAA 465
Query: 519 ACSQAECMGGSQAITSPLPANTPSPSFSKLPPSKASKSSKGKD--GVEVEAPSRKRKLSP 576
S + + + SP+PA PSPS K +K SKSSK KD E+PS K++
Sbjct: 466 TLSIMDSTFKAPSAVSPIPAVIPSPS-HKPSKTKTSKSSKVKDLSTRSDESPSNKKRKPQ 524
Query: 577 GPTTL---------------------KRTCILEPTG----------------KGKPSGCR 599
T+ K+ C+L + +G
Sbjct: 525 SSTSSSSSSSSSSLQTSLSSPLSGPHKKNCVLNASSALNSYQAAPPYNSLSVHNSNNGVS 584
Query: 600 GLSAKTKTALSMGLNGTMGPRVKRAGPLDCRGSPHQLPTPVKASQLENRGAAGHPA-KAL 658
LSAK + + L G V++ G + L P A + A H A +L
Sbjct: 585 PLSAKLEPSGRTSLPGGPADIVRQVGAVGGSSDSCPLSVPSLALHAGDLSLASHNAVSSL 644
Query: 659 PTNCLSEEEVAKKRKNLATYCRPVKAKHCQAGAPADVACSVRRKKPGPALA 709
P + ++ KKRKN ++ +K C+ + SV +K P LA
Sbjct: 645 PLS--FDKSEGKKRKNSSS-----SSKACKITKMPGMN-SVHKKNPPSLLA 687
>gi|23308753 ataxin 7-like 1 isoform 2 [Homo sapiens]
Length = 146
Score = 117 bits (293), Expect = 4e-26
Identities = 54/100 (54%), Positives = 71/100 (71%), Gaps = 1/100 (1%)
Query: 4 RERAAAAMAALERRVPSLDDFAGQSWSSWVERADLPAADGAELEESSKNT-KKLDAMTLI 62
+++ AMA L+R+VPS + F G+ WSSW++ A L +D +LEE+ K K + M L
Sbjct: 22 KQQEGRAMATLDRKVPSPEAFLGKPWSSWIDAAKLHCSDNVDLEEAGKEGGKSREVMRLN 81
Query: 63 KEDMSIFGHCPAHDDFYLVVCNHCSQVVKPQAFQKHCERR 102
KEDM +FGH PAHDDFYLVVC+ C+QVVKPQ FQ HC R+
Sbjct: 82 KEDMHLFGHYPAHDDFYLVVCSACNQVVKPQVFQSHCGRK 121
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 55.1 bits (131), Expect = 2e-07
Identities = 127/586 (21%), Positives = 193/586 (32%), Gaps = 85/586 (14%)
Query: 112 RAPPPPPAPASSQKCHVVNGQGPACRAPGSTKTSSREKGQG---SRSRGHQPPEKTQKDN 168
+ P P P P + N + + ++ SR K + SRS H P + +
Sbjct: 246 KVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSR 305
Query: 169 LCQPGGLTKDSPGKPPM----APPSKEPPG--------------RENIEIIPSEGSSHWA 210
+ SP + P PP + PP R + + S SS +
Sbjct: 306 SRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSS 365
Query: 211 EG-SPPEKEPSGTRLPPKTHRKMARKECDLNRQCGVINPETKKICTRLLTCKIHSVHQRR 269
SPP+K P T PP+ R+++ R+ P T TR HS ++
Sbjct: 366 RSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTR------HSPTPQQ 419
Query: 270 EVQGRAKDFDVLVAEL--KANSRKGESPKEK-SPGRKEQVLERPSQELPSSVQVVAAVAA 326
+ R V K KG +E SP K + +E E ++ AA +
Sbjct: 420 SNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSV 479
Query: 327 PSSTFSVRAKQTYPYCALPRSRASSESELDDEGP------CGGDG-----DPGLFPFPMP 375
R Q S + S S +DE P G G P P P
Sbjct: 480 QQRRQYRRQNQQ------SSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSP 533
Query: 376 RGGTQASSEESEEEGTSDDLHPPPDCHYAT----RPPRPQAFCTFGSRLVSPGCYVFSRR 431
R + +S + PPP + PPR + T R +P RR
Sbjct: 534 RKRQKETSPRGRRRRSPS---PPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPS--PPPRR 588
Query: 432 LDRFCSALSSMLERHLSTHMWKKIPPAAEPPAHLVNSPLSAPLSPSSTGTCPRLPGPTLR 491
S ++R S K A+ PP P SPS P P R
Sbjct: 589 RSPSPRRYSPPIQRRYSPSPPPKRRTASPPP------PPKRRASPS--------PPPKRR 634
Query: 492 PACPASMPPTKDNLVPSYPAGSPSVAAACSQAECMGGS-QAITSPLPANTPSPSFSKLPP 550
+ PP K P SPS+++ + S + SP P SPS P
Sbjct: 635 ---VSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAP 691
Query: 551 SKASKSSKGKDGVEVEAPSRKRKLSPGPTTLKRTCILEPTGKGKPSGCRGLSAKTKTALS 610
+S + G +P R++ SP ++R K K + + + + S
Sbjct: 692 QTSSSPPPVRRGAS-SSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSS 750
Query: 611 MGLNGTMGPRVKRAGPLDCRGSPHQLPTPVKASQLENRGAAGHPAK 656
++G+ P K+ P P+PV++ + P K
Sbjct: 751 RSVSGSPEPAAKK---------PPAPPSPVQSQSPSTNWSPAVPVK 787
Score = 44.3 bits (103), Expect = 4e-04
Identities = 106/507 (20%), Positives = 164/507 (32%), Gaps = 85/507 (16%)
Query: 101 RRHGPLSKLYGRAPPPPPAPASSQKCHVVNGQGPACRAPGSTKTSSREKGQGSRSRGHQP 160
RR P + R PPPP S+ P R S+ + S S SR P
Sbjct: 319 RRPSPRRRTPPRRMPPPPRHRRSRS--------PVRRRRRSSASLSGSSSSSSSSRSRSP 370
Query: 161 PEKTQKDNLCQPGGLTKDSPGKPPM------APPSKEPPG--------------RENIEI 200
P+K K P + SP P +PP+ PP + + +
Sbjct: 371 PKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSV 430
Query: 201 IPSEGSSHWAEGSPPEKEPSGTRLPPKTHRKMARKECDLNRQCGVINPETKKICTRLLTC 260
P S + EK S + P +++ E D + +
Sbjct: 431 SPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAAD------------- 477
Query: 261 KIHSVHQRREVQGRAKDFDVLVAELKANSRKGESPKEKSPGR---KEQVLERPSQELPSS 317
SV QRR+ + + + + ++S S +++ P R K + R + PS
Sbjct: 478 ---SVQQRRQYRRQNQ-------QSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSR 527
Query: 318 VQVVAAVAAPSSTFSVRAKQTYPYCALPRSRASSESELDDEGPCGGDGDPGL--FPFPMP 375
+ T S R ++ P R S S P P P P
Sbjct: 528 SASPSPRKRQKET-SPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPP 586
Query: 376 RGGTQASSEESEEEGTSDDLHPPPDCHYATRPPRPQAFCTFG---SRLVS---PGCYVFS 429
R + + S PPP A+ PP P+ + R VS P S
Sbjct: 587 RRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSS 646
Query: 430 RRLDRFCSALSSMLERHLSTHMWKKIPPAAEPPAHLVNSPLSAPLSPSSTGTCPRL---- 485
R +LSS + S + A P + +SP P +P ++ + P +
Sbjct: 647 PVTKRRSPSLSSKHRKGSSPS--RSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGA 704
Query: 486 ---------PGPTLRPACPASMPPTKDNLVPSYPAGSPSVAAACSQAECMGGSQ------ 530
P P+ RP S P + + SV S G +
Sbjct: 705 SSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKP 764
Query: 531 -AITSPLPANTPSPSFSKLPPSKASKS 556
A SP+ + +PS ++S P K +KS
Sbjct: 765 PAPPSPVQSQSPSTNWSPAVPVKKAKS 791
Score = 35.8 bits (81), Expect = 0.14
Identities = 38/144 (26%), Positives = 53/144 (36%), Gaps = 12/144 (8%)
Query: 92 PQAFQKHCERRHGPLSKLYGRAPPPPP------APASSQKCHVVNGQGPACRAPGSTKTS 145
P+ + +RR+ P R PPP +P+ K V + P R+ TK
Sbjct: 593 PRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRR 652
Query: 146 SREKGQGSRSRGHQPPEKTQKDNLCQPGGLTKDSPGKPPMAP--PSKEPPGRENIEIIPS 203
S R +G P T++ QP + SP P AP S PP R P
Sbjct: 653 SPSLSSKHR-KGSSPSRSTREARSPQPN--KRHSPSPRPRAPQTSSSPPPVRRGASSSPQ 709
Query: 204 EGSSHWAEGSPPEKEPSGTRLPPK 227
S + + P + S T P K
Sbjct: 710 RRQSP-SPSTRPIRRVSRTPEPKK 732
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 54.7 bits (130), Expect = 3e-07
Identities = 51/209 (24%), Positives = 78/209 (37%), Gaps = 21/209 (10%)
Query: 457 PAAEPPAHLVNSP----LSAPLSPSSTGTCPRLPGPTLRPACPASMPPTKDNLV--PSYP 510
P P ++ +P +AP +P++ P P P A P PP L P +P
Sbjct: 229 PKPAAPGTVIQTPPFVGAAAPPAPAAPSP-PAAPAPAAPAAAPPPPPPAPATLARPPGHP 287
Query: 511 AGSPSVAAACSQ-AECMGGSQAITSPLPA----------NTPSPSFSKLPPSKASKSSKG 559
AG P+ A A A G A +P PA P P + P+ K+
Sbjct: 288 AGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESP 347
Query: 560 KDGVEVEAPSRKRKLSPGPTTLKRTCILEPTGKG---KPSGCRGLSAKTKTALSMGLNGT 616
K V+ P+ + + GP + + ++ PT +G P+ + T T L G G
Sbjct: 348 KRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGA 407
Query: 617 MGPRVKRAGPLDCRGSPHQLPTPVKASQL 645
+ + R G L V A +L
Sbjct: 408 VTQSLSRTPTATTSGIRATLTPTVLAPRL 436
Score = 35.8 bits (81), Expect = 0.14
Identities = 57/215 (26%), Positives = 76/215 (35%), Gaps = 44/215 (20%)
Query: 459 AEPPAHLVNSPLSAPLSPSST-----GTCPRLPGPTL--RPACPASMPPTKDNLVPSYPA 511
A P A +P +AP P + G P+ PGP RP PA P L P P
Sbjct: 73 AGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPP-PE 131
Query: 512 GSPSVAAACSQAECMGGSQAITSPLPANTPSPSFSKLPPSKASKSSKGKDGVEVEAPSRK 571
GS A +C+ A P PA P+ P + A+++ G P
Sbjct: 132 GS---AGSCAPVPAAAAVAAGPEPAPAGPAKPAG---PAALAARAGPG--------PGPG 177
Query: 572 RKLSPGPTTLKRTCILEPTGKGKPSGCRGLSAKTKTALSMGLNGTMGPRVKRAGPLDCRG 631
PGP G GKP+G +A + + P V L G
Sbjct: 178 PGPGPGP------------GPGKPAGPGAAQTLNGSAALLNSHHAAAPAVS----LVNNG 221
Query: 632 SPHQLPTPVKASQ---LENR---GAAGHPAKALPT 660
LP P A+ ++ GAA PA A P+
Sbjct: 222 PAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPS 256
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 52.4 bits (124), Expect = 1e-06
Identities = 137/583 (23%), Positives = 180/583 (30%), Gaps = 87/583 (14%)
Query: 115 PPPPAPASSQKCHVVNGQGPAC----RAPGSTKTSSREKGQGSRSRGHQPPEKTQKDNLC 170
PP P S +GPA +AP + TSS K + P
Sbjct: 881 PPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAP 940
Query: 171 QPGGLTKDSPGKPPMAPPSKEPPGRENIEIIPSEGSSHWAEGSPPEKEPSGTRLPPKTHR 230
P T SP P P K P P + +G P P G PP
Sbjct: 941 TPPAATPPSPKGGPATPSPKWAP-------TPPAATPPSPKGGPATPSPKGAPTPPAATP 993
Query: 231 KMARKECDLNRQCGVINPETKKICTRLLTCKIHSVHQRREVQGRAKDFDVLVAELKANSR 290
+ G P K T + A F
Sbjct: 994 PSPKG--------GPATPSPKGAPTPPAVTP-----PSPKGSPAATPFP----------- 1029
Query: 291 KGES--PKEKSPGRKEQVLERPSQELPSSVQVVAAVAAPS-----STFSVRAKQTYPYCA 343
KG S P P K P LP A PS +T S++ T P
Sbjct: 1030 KGASTPPAATPPSPKGSPAATP---LPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAAT 1086
Query: 344 LPRSRASSESELDDEGPCGGDGDPGLFPFPMPRGGTQASSEESEEEGTSDDLHPPPDCHY 403
P + + P G P P P P+GG A+ T P P
Sbjct: 1087 PPSPKGGPATP----SPKGAPMPPAATP-PSPKGGL-ATPPHKGAPTTPAATPPSPKGGL 1140
Query: 404 ATRPPRPQAFCTFGSRLVSPGCYVFS---RRLDRFCSALSSMLERHLSTHMWKKIP--PA 458
AT PP+ A T + SP + + + +A + L+T K P PA
Sbjct: 1141 ATPPPKG-APTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPA 1199
Query: 459 AEPPAH----LVNSPLSAPLSPSSTGTCPR----LPGPTLRPACPASMPPT-KDNLVPSY 509
A PP+ SP AP +P++T P+ P P P PA+ PP+ K
Sbjct: 1200 ATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPP 1259
Query: 510 PAGSPSVAAACSQAECMGG-----------SQAITSPLPANTPS---PSFSKLPPSKASK 555
P G+P+ AA + GG +T P P P+ P + PP+
Sbjct: 1260 PKGAPTPPAA-TPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPP 1318
Query: 556 SSKGKDGVEVE--APSRKRKLSPGPTTLKRTCILEPTGKGKPSGCRGLSAKTKTALSMGL 613
S KG G AP+ P P P+ KG P+ T A +
Sbjct: 1319 SPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSH 1378
Query: 614 NG--TMGPRVKRAGPLDCRGSPHQLPTPVKASQLENRGAAGHP 654
G M P + GP SP PT L + A P
Sbjct: 1379 KGGPAMTPPSPKRGP--AIPSPKGDPTSPAVIPLSPKKAPATP 1419
Score = 52.0 bits (123), Expect = 2e-06
Identities = 60/220 (27%), Positives = 79/220 (35%), Gaps = 18/220 (8%)
Query: 452 WKKIPPAAEPPA----HLVNSPLSAPLSPSSTGTCPR----LPGPTLRPACPASMPPTKD 503
W PPAA PP+ SP AP P++T P+ P P P PA PP+
Sbjct: 961 WAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPK 1020
Query: 504 N--LVPSYPAGSPSVAAACSQAECMGGSQAITSPLPANTPSPSFSKLPPSKASKSSKGKD 561
+P G+ + AA + GS A T PLP P+ + LP K ++
Sbjct: 1021 GSPAATPFPKGASTPPAATPPSP--KGSPAAT-PLPKGAPTTPAATLPSPKGGPATPSLK 1077
Query: 562 GVEVEAPSRKRKLSPGPTTLKRTCILEPTGKGKPSGCRGLSAKT-KTALSMGLNGTMGPR 620
G + GP T P PS GL+ K A + P+
Sbjct: 1078 GAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPK 1137
Query: 621 VKRAGPLDCRGSPHQLPTPVKASQLENRGAAGHPAKALPT 660
A P +G+P TP G A P K PT
Sbjct: 1138 GGLATP-PPKGAP---TTPAATPPSPKGGLATPPPKGAPT 1173
Score = 48.5 bits (114), Expect = 2e-05
Identities = 60/213 (28%), Positives = 80/213 (37%), Gaps = 40/213 (18%)
Query: 468 SPLSAPLSPSSTGTCPR----LPGPTLRPACPASMPPT-KDNLVPSYPAGSPSVAAACSQ 522
SP AP P++T P+ P P P PA+ PP+ K P G+P+ AA
Sbjct: 935 SPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPP 994
Query: 523 AECMGGS----------QAITSP----LPANTPSPSFSKLPPSKASKSSKGKDGVEVEAP 568
+ G + A+T P PA TP P + PP+ S KG +P
Sbjct: 995 SPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKG-------SP 1047
Query: 569 SRKRKLSPGPTTLKRTCILEPTGKGKPSGCRGLSAKTKTALSMGLNGTMGPRVKRAGPLD 628
+ PTT T P+ KG P+ A T A + P + GP
Sbjct: 1048 AATPLPKGAPTTPAATL---PSPKGGPATPSLKGAPTPPAAT--------PPSPKGGP-- 1094
Query: 629 CRGSPHQLPTPVKASQLENRGA-AGHPAKALPT 660
SP P P A+ +G A P K PT
Sbjct: 1095 ATPSPKGAPMPPAATPPSPKGGLATPPHKGAPT 1127
Score = 44.7 bits (104), Expect = 3e-04
Identities = 74/284 (26%), Positives = 97/284 (34%), Gaps = 47/284 (16%)
Query: 456 PPAAEPPAH----LVNSPLSAPLSPSSTGTCPR-----LPGPTLRPACPASMPPTKDN-- 504
PPAA PP+ SP AP P+ T P+ P P PA+ PP+
Sbjct: 988 PPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSP 1047
Query: 505 LVPSYPAGSPSVAAACSQAECMGGS----------QAITSPLPAN---TPSPSFSKLPPS 551
P G+P+ AA + G + A T P P TPSP + +PP+
Sbjct: 1048 AATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPA 1107
Query: 552 KASKSSKGKDGVEVE--APSRKRKLSPGPTTLKRTCILEPTGKGKPSGCRGLSAKTKTAL 609
S KG AP+ P P + + P KG P+ K L
Sbjct: 1108 ATPPSPKGGLATPPHKGAPTTPAATPPSP----KGGLATPPPKGAPTTPAATPPSPKGGL 1163
Query: 610 SMGLNGTMGPRVKRAGPLDCRG-----SPHQLPTPVKASQLENRGAAGHPA-KALPTNCL 663
+ P A P +G SP PT A+ +G P+ K PT
Sbjct: 1164 ATP-PPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPA 1222
Query: 664 SEEEVAKKRKNLATYCRPVKAKHCQAGAPADVACSVRRKKPGPA 707
+ K LAT GAP A + K GPA
Sbjct: 1223 ATPPSPK--GGLAT--------PSPKGAPTTPAATPPSPKGGPA 1256
Score = 43.9 bits (102), Expect = 5e-04
Identities = 95/503 (18%), Positives = 152/503 (30%), Gaps = 110/503 (21%)
Query: 115 PPPPAPASSQKCHVVNGQGPACRAPGSTKTSSREKGQGSRSRGHQPPEKTQKDNLCQPGG 174
PP S +K + A P S + SS S +G P++ L P
Sbjct: 1550 PPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKE-----LLIPPA 1604
Query: 175 LTKDSPGKPPMAPPSKEPPGRENIEIIPSEGSSHWAEGSPPEKEPSGTRLPPKTHRKMAR 234
+T SP + P PP+ PP E P+ P+ P+ + P + +
Sbjct: 1605 VTSPSPKEAP-TPPAVTPPSPEKGPATPA-----------PKGTPTSPPVTPSSLKDSPT 1652
Query: 235 KECDLNRQCGVINPETKKICTRLLTCKIHSVHQRREVQGRAKDFDVLVAELKANSRKGES 294
+ + G P+ K
Sbjct: 1653 SPASVTCKMGATVPQASK----------------------------------------GL 1672
Query: 295 PKEKSPGRKEQVLERPSQELPSSVQVVAAVAAPSSTFSVRAKQTYPYCALPRSRASSESE 354
P +K P ++VL P+ P S ++ A + + P C P ++ S+
Sbjct: 1673 PAKKGPTALKEVLVAPA---PESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGP 1729
Query: 355 LDDEGPCGGDGDPGLFPFPMPRGGTQASSEESEEEGTSDDLHPPPDCHYATRPPRPQAFC 414
L P P L P+ + ++ + + L PP A+ P AF
Sbjct: 1730 LSTVAPA-----PLL---PVQKDSSKTAKGKDASHSPKGPLAPPES--KASTPLTAAAF- 1778
Query: 415 TFGSRLVSPGCYVFSRRLDRFCSALSSMLERHLSTHMWKKIPPAAEPPAHLVNSPLSAPL 474
E+ L + A PP L +P P
Sbjct: 1779 -----------------------------EKVLPKPESASVSAAPSPPVSLPLAPSPVPT 1809
Query: 475 SPSSTGTCPRLPGPTLRPACPASMPPTKDNLVPSYPAGSPSVAAACSQAECMGGSQAITS 534
P P PG L P +D L+P P P Q+ + ++
Sbjct: 1810 LPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPP-EPISGGVPFQSVLVNMPTPKSA 1868
Query: 535 PLPANTPSPSFSKLPPSKASKSSKGKDGVEVEAPSRKRKLSPGPTTLKRTCIL------E 588
+P TPS +K P +K +K S + + P + + S TT + E
Sbjct: 1869 GIPVPTPS---AKQPVTKNNKGSGTESDSDESVPELEEQDSTQATTQQAQLAAAAEIDEE 1925
Query: 589 PTGKGKPSGCRGLSAKTKTALSM 611
P K K S + K + L +
Sbjct: 1926 PVSKAKQSRSEKKARKAMSKLGL 1948
Score = 41.6 bits (96), Expect = 0.003
Identities = 60/224 (26%), Positives = 76/224 (33%), Gaps = 55/224 (24%)
Query: 455 IPPAAEPPAHLVNSPL--SAPLSP--------SSTGTCPR----LPGPTLRPACPASM-P 499
+PP P +VN P P +P S T + P+ P P PA P+
Sbjct: 880 LPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGA 939
Query: 500 PTKDNLVPSYPAGSPSVAAACSQAECMGGSQAITSPLPAN---TPSPSFSKLPPSKASKS 556
PT P P G P A + A T P P TPSP + PP+ S
Sbjct: 940 PTPPAATPPSPKGGP----ATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPS 995
Query: 557 SKGKDGVEVEAPSRKRKLSPGPTTLKRTCILEPTGKGKPSGCRGLSAKTKTALSMGLNGT 616
KG PS K +P T P+ KG P+ T G +
Sbjct: 996 PKGGPA----TPSPKGAPTPPAVT-------PPSPKGSPAA---------TPFPKGAS-- 1033
Query: 617 MGPRVKRAGPLDCRGSPHQLPTPVKASQLENRGAAGHPAKALPT 660
A P +GSP P P +GA PA LP+
Sbjct: 1034 ---TPPAATPPSPKGSPAATPLP--------KGAPTTPAATLPS 1066
Score = 41.6 bits (96), Expect = 0.003
Identities = 55/212 (25%), Positives = 75/212 (35%), Gaps = 35/212 (16%)
Query: 456 PPAAEPPAHLVNSPLSAPLSPSSTGTCPRLPGPTLRPACPASMPPT-KDNLVPSYPAGSP 514
PPAA PP SP P +PS G P PA+ PP+ K L G+P
Sbjct: 1082 PPAATPP-----SPKGGPATPSPKGA----------PMPPAATPPSPKGGLATPPHKGAP 1126
Query: 515 SVAAACSQAECMGGSQAITSPLPANTPSPSFSKLPPSKASKSSKGKDGVEVEAPSRKRKL 574
+ AA + G + +P P P+ + P K ++ G AP+
Sbjct: 1127 TTPAATPPSPKGG----LATPPPKGAPTTPAATPPSPKGGLATPPPKG----APTTPAAT 1178
Query: 575 SPGPTTLKRTCILEPTGKGKPSGCRGLSAKTKTALSMGLNGTMGPRVKRAGPLDCRG--- 631
P P + + P+ KG P+ K L+ + P A P +G
Sbjct: 1179 PPSP----KGGLATPSPKGAPTTPAATPPSPKGGLATP-SPKGAPTTPAATPPSPKGGLA 1233
Query: 632 --SPHQLP-TPVKASQLENRGAAGHPAKALPT 660
SP P TP G A P K PT
Sbjct: 1234 TPSPKGAPTTPAATPPSPKGGPATPPPKGAPT 1265
Score = 40.8 bits (94), Expect = 0.004
Identities = 52/192 (27%), Positives = 74/192 (38%), Gaps = 29/192 (15%)
Query: 470 LSAPLSPSSTGTCPRLPGPTLRPACPASMPPTKDNLVPSYPAGSPSVAAACSQAECMGGS 529
LS+P+SP LP +L P T + P P G+P+ +A +
Sbjct: 824 LSSPVSPVEASF---LPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLS-----P 875
Query: 530 QAITSPLPANTPSPSFSKLPPSKASKSSKGKDGVEVEAPSRKRKLSPGPTTLKRTCILEP 589
+ +T P P TP+PS LP K+G AP + LS ++ K+ P
Sbjct: 876 KGVTLP-PKETPTPSVVNLP--------FPKEGPATPAPKQAPALSMTSSSPKK-ARATP 925
Query: 590 TGKGKPSGCRGLSAKTKTALSMGLNGTMGPRVKRAGPLDCRGSPHQLPTPVKASQLENRG 649
KG P+ A T A + P + GP SP PTP A+ +G
Sbjct: 926 APKGIPASPSPKGAPTPPAAT--------PPSPKGGP--ATPSPKWAPTPPAATPPSPKG 975
Query: 650 AAGHPA-KALPT 660
P+ K PT
Sbjct: 976 GPATPSPKGAPT 987
Score = 40.4 bits (93), Expect = 0.006
Identities = 77/277 (27%), Positives = 97/277 (35%), Gaps = 49/277 (17%)
Query: 456 PPAAEPPAHL--------VNSPLSAPLSPSSTGTCPRLPGPTLRPACPASMPPTKDNLVP 507
PPAA PP+ +P A ++P S P P P PA+ PP+ P
Sbjct: 1266 PPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPS-----P 1320
Query: 508 SYPAGSPSVAAACSQAECMGGSQAITSPLPANTPS-------PSFSKLPPSKASKSSKGK 560
G+P A + S T LPA TPS PS SK P+ + + K
Sbjct: 1321 KGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPS-SKEGPTPPAATPSHK 1379
Query: 561 DGVEVEAPSRKRKLSPGPTTLKRTCILEPTGKGKPS--GCRGLSAKTKTALSMGLNGTMG 618
G + PS KR GP P+ KG P+ LS K A + G
Sbjct: 1380 GGPAMTPPSPKR----GPAI--------PSPKGDPTSPAVIPLSPKKAPATPVTREGAAT 1427
Query: 619 PRVKRAGPLDCRGSPHQLPTPVK---ASQLENRGAAGHPAKALPTNCLSEEEVAKK---R 672
P P P P +K A+ G A +K PT K+
Sbjct: 1428 PSKGDLTP------PAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAP 1481
Query: 673 KNLATYCRPVKAKHCQA--GAPADVACSVRRKKPGPA 707
K +AT P KA A GAP A K PA
Sbjct: 1482 KQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPA 1518
Score = 40.0 bits (92), Expect = 0.008
Identities = 75/289 (25%), Positives = 101/289 (34%), Gaps = 48/289 (16%)
Query: 453 KKIPPAAEP------PAHLVNSPLSAPLSPSSTGTCPRLPGPTL-RPACPASMPPTKDNL 505
KK P P PA + +SP P +PSS P P TL PA++ P + +
Sbjct: 1491 KKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRD-PIAPTATLLSKKTPATLAPKEALI 1549
Query: 506 VPSYPAGSPSVAAAC---SQAECMGGSQAITSPLPANTPS-------PSFSKLPPSKASK 555
P+ SP A +A S+ +SP PA TPS P +PP+ S
Sbjct: 1550 PPAMTVPSPKKTPAIPTPKEAPATPSSKEASSP-PAVTPSTYKGAPSPKELLIPPAVTSP 1608
Query: 556 SSKGKDGVEVEAPSRKRKLSPGPTTLKRTCILEPTGKGKPSG--CRGLSAKTKTALSMGL 613
S K EAP+ P P T P KG P+ S K +
Sbjct: 1609 SPK-------EAPTPPAVTPPSPEKGPAT----PAPKGTPTSPPVTPSSLKDSPTSPASV 1657
Query: 614 NGTMGPRVKRAGP-LDCRGSPHQLPTPVKASQLENRGAAGHPAKALPTNCLSEEEVAKKR 672
MG V +A L + P L + A E+ P + P + K
Sbjct: 1658 TCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGP-------QTKKSS 1710
Query: 673 KNLATYCRPVKAKHCQAGAPADVACSVRRKKPGPALAFEEKCS-TLKSK 720
C AK+ G + VA P P L ++ S T K K
Sbjct: 1711 ATSPPICPDPSAKNGSKGPLSTVA-------PAPLLPVQKDSSKTAKGK 1752
Score = 39.7 bits (91), Expect = 0.010
Identities = 63/259 (24%), Positives = 85/259 (32%), Gaps = 32/259 (12%)
Query: 471 SAPLSPSSTGTCPRLPGPTLRPACPASMP---------PTKDNLVPSYPAGSPSVAAACS 521
+ P++PS TC L L P P S+P P V S A S
Sbjct: 707 NCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASS 766
Query: 522 QAECM---GGSQAITS-----PLPANTPSP-SFSKLPPSKASKSSKGKDGVEVEAPSRKR 572
EC G+ A S A++PSP S P +K + KG G + +
Sbjct: 767 PKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSS 826
Query: 573 KLSPGPTTLKRTCILEPTGKGKPSGCRGLSAKTKTALSMGLNGTMGPRVKRAGPLDCRG- 631
+SP + P G + A T + G P PL +G
Sbjct: 827 PVSPVEASFL------PENSLSFQGSKDSPATTHSPTPPSPKG--APTPSAVTPLSPKGV 878
Query: 632 --SPHQLPTP-VKASQLENRGAAGHPAKALPTNCLSEEEVAKKRKNLATYCRPVKAKHCQ 688
P + PTP V G A K P ++ K R A + + A
Sbjct: 879 TLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAP--KGIPASPSP 936
Query: 689 AGAPADVACSVRRKKPGPA 707
GAP A + K GPA
Sbjct: 937 KGAPTPPAATPPSPKGGPA 955
Score = 39.3 bits (90), Expect = 0.013
Identities = 133/598 (22%), Positives = 188/598 (31%), Gaps = 92/598 (15%)
Query: 104 GPLSKLYGRAPPPPPAPASSQKCHVVNGQGPACRAPGSTKTSSREKGQGSRSRGHQPPEK 163
GP + AP PP A S K + P S + G + PP+
Sbjct: 1254 GPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPAT-----SPPKG 1308
Query: 164 TQKDNLCQPGGLTKDSPGKPPM----APPSKEPPGRENIEIIPSEG-SSHWAEGSPPEKE 218
P K SPG PP PP+ PP + +P+ SS +P KE
Sbjct: 1309 APTPPAATPPS-PKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKE 1367
Query: 219 -PSGTRLPPKTHRKMARKECDLNRQCGVINPE---TKKICTRLLTCKIHSVHQRREVQGR 274
P+ P A R + +P+ T L K + RE
Sbjct: 1368 GPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAAT 1427
Query: 275 AKDFDVL------VAELKANSRKGESPKEKSPGRKEQ----VLERPSQELPSSVQVVAAV 324
D+ V+ KA + +P K + PS + P + + VA
Sbjct: 1428 PSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATS 1487
Query: 325 AAPSSTFSVRAKQTYPYCALPRSRASSESELDDEGPCGGDGDPGLFPFPMPRGGTQASSE 384
++P + A P LP SS E+ P P+ T S +
Sbjct: 1488 SSPKKAPATPAPMGAP--TLPAVIPSSPKEVP--------ATPSSRRDPIAPTATLLSKK 1537
Query: 385 ESEEEGTSDDLHPPPDCHYATRPPRPQAFCTFGSRLVSPGCYVFSRRLDRFCSALSSMLE 444
+ L PP A P P+ + +P S+ +
Sbjct: 1538 TPATLAPKEALIPP-----AMTVPSPKKTPAIPTPKEAPATP----------SSKEASSP 1582
Query: 445 RHLSTHMWKKIPPAAE---PPAHLVNSPLSAPLSPSSTGTCPRLPGPTLRPACPASM-PP 500
++ +K P E PPA SP AP P+ T P P PA PA P
Sbjct: 1583 PAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTP-----PSPEKGPATPAPKGTP 1637
Query: 501 TKDNLVPSYPAGSPSVAAACSQAECMGGS-------------------QAITSPLPANTP 541
T + PS SP+ A+ + C G+ + + +P P +TP
Sbjct: 1638 TSPPVTPSSLKDSPTSPASVT---CKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTP 1694
Query: 542 SPSFSKLPPSKASKSSKGKDGVEVEAPSRKRKLSPGPTTLKRTCILEPTGKGKPSGCRGL 601
+ + KSS + PS K S GP + L P K
Sbjct: 1695 IITAPTRKGPQTKKSSATSPPI-CPDPSAKNG-SKGPLSTVAPAPLLPVQKDSSK----- 1747
Query: 602 SAKTKTALSMGLNGTMGPRVKRAGPLDCRGSPHQLPTPVKASQLENRGAAGHPAKALP 659
+AK K A P K + PL LP P AS AA P +LP
Sbjct: 1748 TAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASV----SAAPSPPVSLP 1801
Score = 31.6 bits (70), Expect = 2.7
Identities = 38/148 (25%), Positives = 55/148 (37%), Gaps = 26/148 (17%)
Query: 462 PAHLVNSPLSAPLSPSSTGTC-------------PRLPGPTLRPACPASMPPTKDNLVPS 508
P+ + ++PL P SS+GT P L GP + PA A P ++
Sbjct: 70 PSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASP----MIAP 125
Query: 509 YPAGSPSVAAACSQAECMGGSQAITSPLPANTPSPSFSKLPPSKASKSSKGKDGVEVEAP 568
G+PS +A + S +S P P+ PPS A S + + AP
Sbjct: 126 TLKGTPSSSAPLALVALAPHSVQKSSAFP-----PNLLTSPPSVAVAESGSV--ITLSAP 178
Query: 569 SRKRKLSPGPTTLKRTCILEPTGKGKPS 596
+ P K + P KG PS
Sbjct: 179 IAPSE--PKTNLNKVPSEVVPNPKGTPS 204
Score = 30.8 bits (68), Expect = 4.6
Identities = 28/120 (23%), Positives = 42/120 (35%), Gaps = 7/120 (5%)
Query: 111 GRAPPP---PPAPASSQKCHVVNGQGPACRAPGSTKTSSREKGQGSRSRGHQPPEKTQKD 167
G + PP PP+P S + P P +T S + +G P
Sbjct: 1031 GASTPPAATPPSPKGSPAATPLPKGAPT--TPAATLPSPKGGPATPSLKGAPTPPAATPP 1088
Query: 168 NLCQPGGLTKDSPGKPPMAPPSKEPPGRENIEIIPSEGSSHWAEGSPPEKEPSGTRLPPK 227
+ GG SP PM P + P + + P +G+ +PP + PPK
Sbjct: 1089 S--PKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPK 1146
>gi|55750053 atrophin-1 [Homo sapiens]
Length = 1190
Score = 50.8 bits (120), Expect = 4e-06
Identities = 115/500 (23%), Positives = 167/500 (33%), Gaps = 91/500 (18%)
Query: 93 QAFQKHCERRHGPLSKLYGRAPPPPPAPASSQKCHVV-----NGQGPACRAPGSTKTSSR 147
Q H H + G P P P + H + + P R P S+ +SS
Sbjct: 323 QPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSS 382
Query: 148 EKGQGSRSRGHQPPEKTQKDNLCQPGGLTKDSPGKPPMAPP------SKEPPGRENIEII 201
S S + P ++ P P PP S +PP + +
Sbjct: 383 AAASSSSS---------SSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPP-KYTQPSL 432
Query: 202 PSEGSSHWAEGSPPEKEPSGTRLPPKTHRKMARKECDLNRQCGVINPETKKICTRLLTCK 261
PS+ W++G PP PP R +A N G P T T
Sbjct: 433 PSQAV--WSQGPPP---------PPPYGRLLANS----NAHPGPFPPSTGAQSTAHPPVS 477
Query: 262 IHSVHQRREVQGRAKDFDVLVAELKANSRKGESPKEKSPGRKEQVLE-------RPSQEL 314
H H +++ Q + + + + + G P PG LE P
Sbjct: 478 THHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPP----PGAFPHPLEGGSSHHAHPYAMS 533
Query: 315 PSSVQVVAAVAAPSSTFSVRAKQTYPYCAL---PRSRASSESELDDEG--PC-------G 362
PS + P+ ++ +Y P S +S+ S +G PC G
Sbjct: 534 PSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQG 593
Query: 363 GDGDPGLFPFPMPRGGTQASSEESEEEGTSDDLHPPPDCHYATRPPRPQAFCTFGSRLVS 422
G P +PFP T +S+ S T + P + PP P + G R S
Sbjct: 594 PQGAP--YPFPPVPTVTTSSATLSTVIAT---VASSPAGYKTASPPGPPPY---GKRAPS 645
Query: 423 PGCYVFSRRLDRFCSALSSMLERHLSTHMWKKIPPAAEPPAHLVNSPL--SAPLSPSSTG 480
PG Y + + S R + ++ P A P SP PL P+
Sbjct: 646 PGAYKTATPPGYKPGSPPSF--RTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPS 703
Query: 481 TCPRLPGPTLRPACPASMPPTKDNLVPSYPAGSPSVAAACSQAECMGGSQAITSPL-PAN 539
P LP P PA PAS PP + PA + SP+ PA
Sbjct: 704 GLPSLPPP---PAAPASGPPLSATQIKQEPAEE---------------YETPESPVPPAR 745
Query: 540 TPSPSFSKLP-PSKASKSSK 558
+PSP + PS AS+S++
Sbjct: 746 SPSPPPKVVDVPSHASQSAR 765
Score = 38.1 bits (87), Expect = 0.029
Identities = 45/136 (33%), Positives = 60/136 (44%), Gaps = 25/136 (18%)
Query: 456 PPAAEP-------PAHLVNSPLSAPL-SPSSTGT----CPRLP--GPTLRPACPASMPPT 501
PPA P P L PL L SP + G P P GPTL P+ P S+PP
Sbjct: 304 PPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPS-PHSLPPA 362
Query: 502 KDNLVPSYP-----AGSPSVAAACSQAECMGGSQAITSPLPANTPSPSF--SKLPPSKAS 554
+ P+ P + S S +AA S + S A SP PA+ PS+ S PP+ S
Sbjct: 363 SSS-APAPPMRFPYSSSSSSSAAASSSSSSSSSSA--SPFPASQALPSYPHSFPPPTSLS 419
Query: 555 KSSKGKDGVEVEAPSR 570
S++ + PS+
Sbjct: 420 VSNQPPKYTQPSLPSQ 435
Score = 33.9 bits (76), Expect = 0.54
Identities = 81/369 (21%), Positives = 111/369 (30%), Gaps = 81/369 (21%)
Query: 286 KANSRKGESPKEKSPGRKEQVLERPSQELPSSVQVVAAVAAPSSTFSVRAKQTYPYCALP 345
KA + +PK GR E++ E S+E AP K+T LP
Sbjct: 56 KARVEEASTPKVNKQGRSEEISESESEE----------TNAP--------KKTKTEQELP 97
Query: 346 RSRASSESELDDEGPCGGDG--DP--------GLFPFPMPRGGTQASSEESE--EEGTSD 393
R ++ S+ + D DG DP P G + S+ S +G +
Sbjct: 98 RPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPAR 157
Query: 394 DLHPPPDCHYATRPPRPQAFCTFGSRLVSPGCYVFSRRLDRFCSALSSMLERHLSTHMWK 453
HPPP PP PQ D + E H S
Sbjct: 158 PYHPPP-----LFPPSPQP-------------------PDSTPRQPEASFEPHPSVTPTG 193
Query: 454 KIPPAAEPPAHLVNSPLSAPLSPSSTGTCPRLPGPTLRPACPASMPPTKDNLVPSYPAGS 513
P P + + +P AP P P P ++ P G
Sbjct: 194 YHAPMEPPTSRMFQAPPGAP------------------PPHPQLYPGGTGGVLSGPPMGP 235
Query: 514 PSVAAACSQAECMGGSQAITSPLPANTPSPSFSKLPPSKASKSSKGKDGV-EVEAPSRKR 572
AA S GG Q P + S S PP+K + G + P+
Sbjct: 236 KGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFP 295
Query: 573 KLSPGPTTLKRTCILEPTGKGKPS----GCRGLSAKTKTALSMGLNGTMGPRVKRAGPLD 628
++P L L P S G + L + +MG P GP
Sbjct: 296 HVTP---NLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGP-T 351
Query: 629 CRGSPHQLP 637
SPH LP
Sbjct: 352 LAPSPHSLP 360
>gi|55750041 atrophin-1 [Homo sapiens]
Length = 1190
Score = 50.8 bits (120), Expect = 4e-06
Identities = 115/500 (23%), Positives = 167/500 (33%), Gaps = 91/500 (18%)
Query: 93 QAFQKHCERRHGPLSKLYGRAPPPPPAPASSQKCHVV-----NGQGPACRAPGSTKTSSR 147
Q H H + G P P P + H + + P R P S+ +SS
Sbjct: 323 QPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSS 382
Query: 148 EKGQGSRSRGHQPPEKTQKDNLCQPGGLTKDSPGKPPMAPP------SKEPPGRENIEII 201
S S + P ++ P P PP S +PP + +
Sbjct: 383 AAASSSSS---------SSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPP-KYTQPSL 432
Query: 202 PSEGSSHWAEGSPPEKEPSGTRLPPKTHRKMARKECDLNRQCGVINPETKKICTRLLTCK 261
PS+ W++G PP PP R +A N G P T T
Sbjct: 433 PSQAV--WSQGPPP---------PPPYGRLLANS----NAHPGPFPPSTGAQSTAHPPVS 477
Query: 262 IHSVHQRREVQGRAKDFDVLVAELKANSRKGESPKEKSPGRKEQVLE-------RPSQEL 314
H H +++ Q + + + + + G P PG LE P
Sbjct: 478 THHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPP----PGAFPHPLEGGSSHHAHPYAMS 533
Query: 315 PSSVQVVAAVAAPSSTFSVRAKQTYPYCAL---PRSRASSESELDDEG--PC-------G 362
PS + P+ ++ +Y P S +S+ S +G PC G
Sbjct: 534 PSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQG 593
Query: 363 GDGDPGLFPFPMPRGGTQASSEESEEEGTSDDLHPPPDCHYATRPPRPQAFCTFGSRLVS 422
G P +PFP T +S+ S T + P + PP P + G R S
Sbjct: 594 PQGAP--YPFPPVPTVTTSSATLSTVIAT---VASSPAGYKTASPPGPPPY---GKRAPS 645
Query: 423 PGCYVFSRRLDRFCSALSSMLERHLSTHMWKKIPPAAEPPAHLVNSPL--SAPLSPSSTG 480
PG Y + + S R + ++ P A P SP PL P+
Sbjct: 646 PGAYKTATPPGYKPGSPPSF--RTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPS 703
Query: 481 TCPRLPGPTLRPACPASMPPTKDNLVPSYPAGSPSVAAACSQAECMGGSQAITSPL-PAN 539
P LP P PA PAS PP + PA + SP+ PA
Sbjct: 704 GLPSLPPP---PAAPASGPPLSATQIKQEPAEE---------------YETPESPVPPAR 745
Query: 540 TPSPSFSKLP-PSKASKSSK 558
+PSP + PS AS+S++
Sbjct: 746 SPSPPPKVVDVPSHASQSAR 765
Score = 38.1 bits (87), Expect = 0.029
Identities = 45/136 (33%), Positives = 60/136 (44%), Gaps = 25/136 (18%)
Query: 456 PPAAEP-------PAHLVNSPLSAPL-SPSSTGT----CPRLP--GPTLRPACPASMPPT 501
PPA P P L PL L SP + G P P GPTL P+ P S+PP
Sbjct: 304 PPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPS-PHSLPPA 362
Query: 502 KDNLVPSYP-----AGSPSVAAACSQAECMGGSQAITSPLPANTPSPSF--SKLPPSKAS 554
+ P+ P + S S +AA S + S A SP PA+ PS+ S PP+ S
Sbjct: 363 SSS-APAPPMRFPYSSSSSSSAAASSSSSSSSSSA--SPFPASQALPSYPHSFPPPTSLS 419
Query: 555 KSSKGKDGVEVEAPSR 570
S++ + PS+
Sbjct: 420 VSNQPPKYTQPSLPSQ 435
Score = 33.9 bits (76), Expect = 0.54
Identities = 81/369 (21%), Positives = 111/369 (30%), Gaps = 81/369 (21%)
Query: 286 KANSRKGESPKEKSPGRKEQVLERPSQELPSSVQVVAAVAAPSSTFSVRAKQTYPYCALP 345
KA + +PK GR E++ E S+E AP K+T LP
Sbjct: 56 KARVEEASTPKVNKQGRSEEISESESEE----------TNAP--------KKTKTEQELP 97
Query: 346 RSRASSESELDDEGPCGGDG--DP--------GLFPFPMPRGGTQASSEESE--EEGTSD 393
R ++ S+ + D DG DP P G + S+ S +G +
Sbjct: 98 RPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPAR 157
Query: 394 DLHPPPDCHYATRPPRPQAFCTFGSRLVSPGCYVFSRRLDRFCSALSSMLERHLSTHMWK 453
HPPP PP PQ D + E H S
Sbjct: 158 PYHPPP-----LFPPSPQP-------------------PDSTPRQPEASFEPHPSVTPTG 193
Query: 454 KIPPAAEPPAHLVNSPLSAPLSPSSTGTCPRLPGPTLRPACPASMPPTKDNLVPSYPAGS 513
P P + + +P AP P P P ++ P G
Sbjct: 194 YHAPMEPPTSRMFQAPPGAP------------------PPHPQLYPGGTGGVLSGPPMGP 235
Query: 514 PSVAAACSQAECMGGSQAITSPLPANTPSPSFSKLPPSKASKSSKGKDGV-EVEAPSRKR 572
AA S GG Q P + S S PP+K + G + P+
Sbjct: 236 KGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFP 295
Query: 573 KLSPGPTTLKRTCILEPTGKGKPS----GCRGLSAKTKTALSMGLNGTMGPRVKRAGPLD 628
++P L L P S G + L + +MG P GP
Sbjct: 296 HVTP---NLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGP-T 351
Query: 629 CRGSPHQLP 637
SPH LP
Sbjct: 352 LAPSPHSLP 360
>gi|34878787 ring finger protein 25 [Homo sapiens]
Length = 459
Score = 47.8 bits (112), Expect = 4e-05
Identities = 41/135 (30%), Positives = 56/135 (41%), Gaps = 8/135 (5%)
Query: 116 PPPAPASSQK-CHVVNGQGPACRAPGSTKTSSREKGQGSRSRGHQPPEKTQKDNLCQPGG 174
PPP P ++Q C + G + G T+ + + + SR QP + K C
Sbjct: 305 PPPLPVATQHICEKIPGTRSNQQRLGETQKAMLDPPKPSRGPWRQPERRHPKGGECHAPK 364
Query: 175 LTKDSPGKPPMAPPSKEPPGRENIEIIPSEGSSHWAEGSPPEKEP-SGTRLPPKTHRKMA 233
T+D+ PP P KEP +++ P E S EG P EK P S PP+ R
Sbjct: 365 GTRDTQELPPPEGPLKEP-----MDLKP-EPHSQGVEGPPQEKGPGSWQGPPPRRTRDCV 418
Query: 234 RKECDLNRQCGVINP 248
R E R G P
Sbjct: 419 RWERSKGRTPGSSYP 433
>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
sapiens]
Length = 1560
Score = 46.2 bits (108), Expect = 1e-04
Identities = 68/286 (23%), Positives = 101/286 (35%), Gaps = 36/286 (12%)
Query: 293 ESPKEKSPGRKEQVLERPSQELPSSVQVVAAVAAPSSTFSVRAKQTYPYCALPRSRASSE 352
++P ++ + +PS L SS + + PS+T + Q LP+ R S+
Sbjct: 649 QAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQER--SQ 706
Query: 353 SELDDEGPCGGDGDPGLFPFPMPRGGTQASSEESEEEGTSDDLHPPPDCHYATRPPRPQA 412
L EGP + P P ++ ++ G L P A+ P PQ
Sbjct: 707 QPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAG----LGPQAPDSQASPAPAPQI 762
Query: 413 FCTFGSRLVSPGCYVFSRRLDRFCSALSSMLERHLSTHMWKKIP--------PAAEPPAH 464
+ L PG + S L T + P P +EPP H
Sbjct: 763 --PAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLH 820
Query: 465 LVNSPLSAP-------------LSPSSTGTCPRLPGPTLRPACPASMPPTKDNLVPSYPA 511
P + P + P ++ P PGP P P S PP + +P P
Sbjct: 821 PCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPP--EGPLPPAPH 878
Query: 512 GSPSVAAACSQAECMGGSQAITSPLPANTPSPSFSKLPPSKASKSS 557
PS S + + S +S LPA TPS + PPS+ S
Sbjct: 879 LPPS-----STSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKS 919
Score = 32.7 bits (73), Expect = 1.2
Identities = 31/122 (25%), Positives = 42/122 (34%), Gaps = 27/122 (22%)
Query: 115 PPPPAPASSQKCHVVNGQ--------GPACRAPGSTKTSSREKGQGSRSRGHQPPEKTQK 166
PPP AP + V+ Q PA APG + R + Q PPE
Sbjct: 823 PPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQ--------PPE---- 870
Query: 167 DNLCQPGGLTKDSPGKPPMAPPSKEPPGRENIEIIPSEGSSHWAEGSPPEKEPSGTRLPP 226
G +P PP + S E +P+ S + PP + P + PP
Sbjct: 871 -------GPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPP 923
Query: 227 KT 228
T
Sbjct: 924 PT 925
Score = 32.3 bits (72), Expect = 1.6
Identities = 34/119 (28%), Positives = 46/119 (38%), Gaps = 25/119 (21%)
Query: 113 APPPP--PAPASSQKCHVVNGQGPACRAPGSTKTSSRE---------KGQGSRSRGHQPP 161
APPP PAPA+ V G G +AP S + + KG G S P
Sbjct: 726 APPPAQDPAPATP----VAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPH 781
Query: 162 EKTQKDNLCQPGGLTKDSPGKPPMAPPSKEPPGRENIEIIPSEGSSHWAEGSPPEKEPS 220
+ P G + P P PPS+ P +++ PSE H PP+ P+
Sbjct: 782 QA--------PLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLH--PCPPPQAPPT 830
Score = 31.6 bits (70), Expect = 2.7
Identities = 75/318 (23%), Positives = 98/318 (30%), Gaps = 51/318 (16%)
Query: 326 APSSTFSVRAKQTYPYCA-LPRSRASSESELDDEGPCGGDGDPGLFPFPMPRGGTQASSE 384
AP S S P A L SS L + P G P L P P S
Sbjct: 749 APDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDS--PHL---PSPHPTRPPSRP 803
Query: 385 ESEEEGTSDDLHPPPDCHYATRPPRPQAFCTFGSRLVSPGCYVFSRRLDRFCSALSSMLE 444
S + S PP + PP PQA T PG +V +L
Sbjct: 804 PSRPQSVS---RPPSEPPLHPCPP-PQAPPTL------PGIFVIQNQLG----------- 842
Query: 445 RHLSTHMWKKIPPAAEPPAHLVNSPLSAPLSPSSTGT-CPRLPGPTLRPACPASMPPTKD 503
+PP A PA P PL P S P P P L P+ +S +
Sbjct: 843 ----------VPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSS 892
Query: 504 NLVPSYPAGSPSVAAACSQAECMGGSQAITSPLPANTPSPSFSKLPPSKASKSSKGKDGV 563
PA +PS + P + TP P+ +P A +
Sbjct: 893 ETSSRLPAPTPS--------DFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQ 944
Query: 564 EVEAPSRKRKLSPGPTTLKRTCILEPTGKGKPSGCRGLSAKTKTALSMGLNGTMGPRVKR 623
V P P P L P+G + G A +T+ S+G + V
Sbjct: 945 MVTTPF---PALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLV 1001
Query: 624 AG--PLDCRGSPHQLPTP 639
+G P +P P P
Sbjct: 1002 SGQAPSGTPTAPSHAPAP 1019
>gi|223972704 hypothetical protein LOC284418 [Homo sapiens]
Length = 922
Score = 45.1 bits (105), Expect = 2e-04
Identities = 47/176 (26%), Positives = 71/176 (40%), Gaps = 26/176 (14%)
Query: 447 LSTHMWKKIPPAAEPPAHLVNSPLSAPLSPSSTGTCPRLPGPTLRP---------ACPAS 497
+ +H PP + P+ LV S AP + P +P + +P A AS
Sbjct: 388 MGSHQGPGPPPCQKAPSGLVTS-CKAPFLVDQSQKLPAVPASSWKPPPGLAPPQKAPAAS 446
Query: 498 MPPTKDNLVPSYPAGSPSVAAACSQAECM-----GGSQAITSPLPAN-TPSPSFSKLPPS 551
PP K VP+ +P+V A +A + S A SP A+ P+P PPS
Sbjct: 447 APPRKAPAVPAPSQKAPAVPAPSQKAPAIPAPSRKASAASASPRKASAVPAPPQKTPPPS 506
Query: 552 KASKS--SKGKDGVEVEAPSRKRKLSPGPT--------TLKRTCILEPTGKGKPSG 597
+ + S + + V AP +K L P P+ T + + P +GK G
Sbjct: 507 QKAPSVPTIPQKAVSPTAPKKKSLLLPAPSQKALPTSPTEYQMALSPPASRGKLPG 562
>gi|33946327 nucleoporin 214kDa [Homo sapiens]
Length = 2090
Score = 44.3 bits (103), Expect = 4e-04
Identities = 77/329 (23%), Positives = 122/329 (37%), Gaps = 45/329 (13%)
Query: 248 PETKKICTRLLTCKIHSVHQRREVQGRAKDFDVLVAELKANSRK-GESPKEKSPGRKEQV 306
P + T + C + ++Q V+ K + L E + + G +P + + Q
Sbjct: 387 PVLMLLSTDGVLCPFYMINQNPGVKSLIKTPERLSLEGERQPKSPGSTPTTPTSSQAPQK 446
Query: 307 LERPSQELPSSVQVVAAVAAPSSTFSVRAKQTYPYCALPRSRASSESELDDEGPCGGDGD 366
L+ + P+S+ ++ AAP +TFS+ P P + S L G+
Sbjct: 447 LDASAAAAPASLPP-SSPAAPIATFSL-----LPAGGAPTVFSFGSSSLKSSATVTGE-- 498
Query: 367 PGLFPFPMPRGGTQASSEESEEEGTSDDLHPPPDCHYATRPPRPQAFCTFGSRLVSPGCY 426
P SS+ + G S PP A+ P P A V+P
Sbjct: 499 ------PPSYSSGSDSSKAAPGPGPSTFSFVPPS--KASLAPTPAA------SPVAPSAA 544
Query: 427 VFSRRLDRFCSALSSMLERHLSTH---MWKKIPPAAEP---------PAHLVNSPLSA-- 472
FS F L S +S M PP+ A ++P+S+
Sbjct: 545 SFSFGSSGFKPTLESTPVPSVSAPNIAMKPSFPPSTSAVKVNLSEKFTAAATSTPVSSSQ 604
Query: 473 ---PLSPSSTGTCPRLPGPTLRP---ACPASMPPTKDNLVPSYPAGSPSVAAACSQAECM 526
P+SP S+ + P GP P + P S P K +++PS P+G + ++ +
Sbjct: 605 SAPPMSPFSSASKPAASGPLSHPTPLSAPPSSVPLKSSVLPS-PSGRSAQGSSSPVPSMV 663
Query: 527 GGSQAITSPLPANTPSPSFSKLPPSKASK 555
S IT P A SP L P+ A K
Sbjct: 664 QKSPRITPP-AAKPGSPQAKSLQPAVAEK 691
Score = 30.8 bits (68), Expect = 4.6
Identities = 28/85 (32%), Positives = 41/85 (48%), Gaps = 9/85 (10%)
Query: 473 PLSPSSTGTCPRLPGPTLRPACPASMPPTKDNLVPSYPAGSPSVAAACSQAECMGGSQAI 532
P S + + PGP P+ + +PP+K +L P+ PA SP +A S + G +
Sbjct: 500 PSYSSGSDSSKAAPGPG--PSTFSFVPPSKASLAPT-PAASPVAPSAASFSFGSSGFK-- 554
Query: 533 TSPLPANTPSPSFSKLPPSKASKSS 557
P +TP PS S P+ A K S
Sbjct: 555 --PTLESTPVPSVS--APNIAMKPS 575
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 44.3 bits (103), Expect = 4e-04
Identities = 95/460 (20%), Positives = 141/460 (30%), Gaps = 37/460 (8%)
Query: 294 SPKEKSPGRKEQVLERPSQELPSSVQVVAAVAA----------PSSTFSVRAKQTYPYCA 343
+PKE +P KE P + P++ + A P+ T + T P
Sbjct: 329 TPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEP 388
Query: 344 LPRSRASSESELDDEGPCGGDGDPGLFPFPMPRGGTQASSEESEEEGTSDDLHPPPDCHY 403
P + S+ + + P P P P + + +E + P P
Sbjct: 389 APTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPK 448
Query: 404 ATRPPRPQAFCTFGSRLVSPGCYVFSRRLDRFCSALSSMLERHLSTHMWKKIPPAAEPPA 463
P P+ ++ +P +A ++ ++ T K P E PA
Sbjct: 449 EPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTP-KKLTPTTPEKLAPTTPEKPA 507
Query: 464 HLVNSPLSAPLSPSSTGTCPRLPGPTLRPACPASMPPTKDNLVPSYPA-GSPSVAAACSQ 522
L+ T T P P PT A + P P PA +P A +
Sbjct: 508 PTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP 567
Query: 523 AECMGGSQAITSPLPANTPSPSFSKLPPSK--ASKSSKGKDGVEVEAPSRKRKLSPGPTT 580
E + T+P P+P+ K P K A ++K + P+ PTT
Sbjct: 568 KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTT 627
Query: 581 LKRTCILEPTGKGKPSGCRGLSAKTKTALSMGLNGTMGPRVKRAGPLDCRG-----SPHQ 635
K PT +P+ T P K P +G S
Sbjct: 628 PKEPA---PTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKP 684
Query: 636 LPTPVK--ASQLENRGAAGHPAKALPTN------CLSEEEVAKKRKNLAT-YCRPVKAKH 686
PT K A A P K PT SE K T + P ++
Sbjct: 685 APTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTP 744
Query: 687 CQAGAPADVACSVRRKKPG------PALAFEEKCSTLKSK 720
+ P A K+PG PA E +T K K
Sbjct: 745 ELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDK 784
Score = 35.0 bits (79), Expect = 0.24
Identities = 59/274 (21%), Positives = 84/274 (30%), Gaps = 28/274 (10%)
Query: 457 PAAEPPAHLVNSPLS----APLSPSSTGTCPRLPGPTLRPACPASMPPTKDNLVPSYPAG 512
P P + ++P + AP + S T P+ P PT + P PA
Sbjct: 229 PKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAP 288
Query: 513 SPSVAAACSQAECMGGSQAITSPLPANTPSPSFSKLPPSKASKSSKGKDGVEVEAPSRKR 572
+ + +A + E + +P P+P+ K P K AP+ K
Sbjct: 289 TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKE---------PAPTTK- 338
Query: 573 KLSPGPTTLKRTCILEPTGKGKPSGCRGLSAKTKTALSMGLNGTMGP---RVKRAGPLDC 629
P PTT K PT KP+ T T P K P
Sbjct: 339 --EPAPTTPKEPA---PTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTT 393
Query: 630 RGSPHQLPTPVKASQLENRGAAGHPAKALPTNCLSEEEVAKKRKNLATYCRPVKA--KHC 687
+ +P P + + A P + PT K T +P K
Sbjct: 394 KSAPTTTKEPAPTT---TKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEP 450
Query: 688 QAGAPADVACSVRRKKPGPALAFEEKCSTLKSKA 721
P + A KKP P E +T K A
Sbjct: 451 APTTPKEPA-PTTTKKPAPTTPKEPAPTTPKETA 483
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 44.3 bits (103), Expect = 4e-04
Identities = 95/460 (20%), Positives = 141/460 (30%), Gaps = 37/460 (8%)
Query: 294 SPKEKSPGRKEQVLERPSQELPSSVQVVAAVAA----------PSSTFSVRAKQTYPYCA 343
+PKE +P KE P + P++ + A P+ T + T P
Sbjct: 370 TPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEP 429
Query: 344 LPRSRASSESELDDEGPCGGDGDPGLFPFPMPRGGTQASSEESEEEGTSDDLHPPPDCHY 403
P + S+ + + P P P P + + +E + P P
Sbjct: 430 APTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPK 489
Query: 404 ATRPPRPQAFCTFGSRLVSPGCYVFSRRLDRFCSALSSMLERHLSTHMWKKIPPAAEPPA 463
P P+ ++ +P +A ++ ++ T K P E PA
Sbjct: 490 EPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTP-KKLTPTTPEKLAPTTPEKPA 548
Query: 464 HLVNSPLSAPLSPSSTGTCPRLPGPTLRPACPASMPPTKDNLVPSYPA-GSPSVAAACSQ 522
L+ T T P P PT A + P P PA +P A +
Sbjct: 549 PTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP 608
Query: 523 AECMGGSQAITSPLPANTPSPSFSKLPPSK--ASKSSKGKDGVEVEAPSRKRKLSPGPTT 580
E + T+P P+P+ K P K A ++K + P+ PTT
Sbjct: 609 KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTT 668
Query: 581 LKRTCILEPTGKGKPSGCRGLSAKTKTALSMGLNGTMGPRVKRAGPLDCRG-----SPHQ 635
K PT +P+ T P K P +G S
Sbjct: 669 PKEPA---PTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKP 725
Query: 636 LPTPVK--ASQLENRGAAGHPAKALPTN------CLSEEEVAKKRKNLAT-YCRPVKAKH 686
PT K A A P K PT SE K T + P ++
Sbjct: 726 APTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTP 785
Query: 687 CQAGAPADVACSVRRKKPG------PALAFEEKCSTLKSK 720
+ P A K+PG PA E +T K K
Sbjct: 786 ELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDK 825
Score = 35.0 bits (79), Expect = 0.24
Identities = 59/274 (21%), Positives = 84/274 (30%), Gaps = 28/274 (10%)
Query: 457 PAAEPPAHLVNSPLS----APLSPSSTGTCPRLPGPTLRPACPASMPPTKDNLVPSYPAG 512
P P + ++P + AP + S T P+ P PT + P PA
Sbjct: 270 PKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAP 329
Query: 513 SPSVAAACSQAECMGGSQAITSPLPANTPSPSFSKLPPSKASKSSKGKDGVEVEAPSRKR 572
+ + +A + E + +P P+P+ K P K AP+ K
Sbjct: 330 TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKE---------PAPTTK- 379
Query: 573 KLSPGPTTLKRTCILEPTGKGKPSGCRGLSAKTKTALSMGLNGTMGP---RVKRAGPLDC 629
P PTT K PT KP+ T T P K P
Sbjct: 380 --EPAPTTPKEPA---PTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTT 434
Query: 630 RGSPHQLPTPVKASQLENRGAAGHPAKALPTNCLSEEEVAKKRKNLATYCRPVKA--KHC 687
+ +P P + + A P + PT K T +P K
Sbjct: 435 KSAPTTTKEPAPTT---TKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEP 491
Query: 688 QAGAPADVACSVRRKKPGPALAFEEKCSTLKSKA 721
P + A KKP P E +T K A
Sbjct: 492 APTTPKEPA-PTTTKKPAPTTPKEPAPTTPKETA 524
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 44.3 bits (103), Expect = 4e-04
Identities = 95/460 (20%), Positives = 141/460 (30%), Gaps = 37/460 (8%)
Query: 294 SPKEKSPGRKEQVLERPSQELPSSVQVVAAVAA----------PSSTFSVRAKQTYPYCA 343
+PKE +P KE P + P++ + A P+ T + T P
Sbjct: 422 TPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEP 481
Query: 344 LPRSRASSESELDDEGPCGGDGDPGLFPFPMPRGGTQASSEESEEEGTSDDLHPPPDCHY 403
P + S+ + + P P P P + + +E + P P
Sbjct: 482 APTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPK 541
Query: 404 ATRPPRPQAFCTFGSRLVSPGCYVFSRRLDRFCSALSSMLERHLSTHMWKKIPPAAEPPA 463
P P+ ++ +P +A ++ ++ T K P E PA
Sbjct: 542 EPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTP-KKLTPTTPEKLAPTTPEKPA 600
Query: 464 HLVNSPLSAPLSPSSTGTCPRLPGPTLRPACPASMPPTKDNLVPSYPA-GSPSVAAACSQ 522
L+ T T P P PT A + P P PA +P A +
Sbjct: 601 PTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP 660
Query: 523 AECMGGSQAITSPLPANTPSPSFSKLPPSK--ASKSSKGKDGVEVEAPSRKRKLSPGPTT 580
E + T+P P+P+ K P K A ++K + P+ PTT
Sbjct: 661 KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTT 720
Query: 581 LKRTCILEPTGKGKPSGCRGLSAKTKTALSMGLNGTMGPRVKRAGPLDCRG-----SPHQ 635
K PT +P+ T P K P +G S
Sbjct: 721 PKEPA---PTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKP 777
Query: 636 LPTPVK--ASQLENRGAAGHPAKALPTN------CLSEEEVAKKRKNLAT-YCRPVKAKH 686
PT K A A P K PT SE K T + P ++
Sbjct: 778 APTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTP 837
Query: 687 CQAGAPADVACSVRRKKPG------PALAFEEKCSTLKSK 720
+ P A K+PG PA E +T K K
Sbjct: 838 ELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDK 877
Score = 35.0 bits (79), Expect = 0.24
Identities = 59/274 (21%), Positives = 84/274 (30%), Gaps = 28/274 (10%)
Query: 457 PAAEPPAHLVNSPLS----APLSPSSTGTCPRLPGPTLRPACPASMPPTKDNLVPSYPAG 512
P P + ++P + AP + S T P+ P PT + P PA
Sbjct: 322 PKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAP 381
Query: 513 SPSVAAACSQAECMGGSQAITSPLPANTPSPSFSKLPPSKASKSSKGKDGVEVEAPSRKR 572
+ + +A + E + +P P+P+ K P K AP+ K
Sbjct: 382 TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKE---------PAPTTK- 431
Query: 573 KLSPGPTTLKRTCILEPTGKGKPSGCRGLSAKTKTALSMGLNGTMGP---RVKRAGPLDC 629
P PTT K PT KP+ T T P K P
Sbjct: 432 --EPAPTTPKEPA---PTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTT 486
Query: 630 RGSPHQLPTPVKASQLENRGAAGHPAKALPTNCLSEEEVAKKRKNLATYCRPVKA--KHC 687
+ +P P + + A P + PT K T +P K
Sbjct: 487 KSAPTTTKEPAPTT---TKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEP 543
Query: 688 QAGAPADVACSVRRKKPGPALAFEEKCSTLKSKA 721
P + A KKP P E +T K A
Sbjct: 544 APTTPKEPA-PTTTKKPAPTTPKEPAPTTPKETA 576
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 44.3 bits (103), Expect = 4e-04
Identities = 95/460 (20%), Positives = 141/460 (30%), Gaps = 37/460 (8%)
Query: 294 SPKEKSPGRKEQVLERPSQELPSSVQVVAAVAA----------PSSTFSVRAKQTYPYCA 343
+PKE +P KE P + P++ + A P+ T + T P
Sbjct: 463 TPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEP 522
Query: 344 LPRSRASSESELDDEGPCGGDGDPGLFPFPMPRGGTQASSEESEEEGTSDDLHPPPDCHY 403
P + S+ + + P P P P + + +E + P P
Sbjct: 523 APTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPK 582
Query: 404 ATRPPRPQAFCTFGSRLVSPGCYVFSRRLDRFCSALSSMLERHLSTHMWKKIPPAAEPPA 463
P P+ ++ +P +A ++ ++ T K P E PA
Sbjct: 583 EPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTP-KKLTPTTPEKLAPTTPEKPA 641
Query: 464 HLVNSPLSAPLSPSSTGTCPRLPGPTLRPACPASMPPTKDNLVPSYPA-GSPSVAAACSQ 522
L+ T T P P PT A + P P PA +P A +
Sbjct: 642 PTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP 701
Query: 523 AECMGGSQAITSPLPANTPSPSFSKLPPSK--ASKSSKGKDGVEVEAPSRKRKLSPGPTT 580
E + T+P P+P+ K P K A ++K + P+ PTT
Sbjct: 702 KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTT 761
Query: 581 LKRTCILEPTGKGKPSGCRGLSAKTKTALSMGLNGTMGPRVKRAGPLDCRG-----SPHQ 635
K PT +P+ T P K P +G S
Sbjct: 762 PKEPA---PTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKP 818
Query: 636 LPTPVK--ASQLENRGAAGHPAKALPTN------CLSEEEVAKKRKNLAT-YCRPVKAKH 686
PT K A A P K PT SE K T + P ++
Sbjct: 819 APTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTP 878
Query: 687 CQAGAPADVACSVRRKKPG------PALAFEEKCSTLKSK 720
+ P A K+PG PA E +T K K
Sbjct: 879 ELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDK 918
Score = 35.0 bits (79), Expect = 0.24
Identities = 59/274 (21%), Positives = 84/274 (30%), Gaps = 28/274 (10%)
Query: 457 PAAEPPAHLVNSPLS----APLSPSSTGTCPRLPGPTLRPACPASMPPTKDNLVPSYPAG 512
P P + ++P + AP + S T P+ P PT + P PA
Sbjct: 363 PKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAP 422
Query: 513 SPSVAAACSQAECMGGSQAITSPLPANTPSPSFSKLPPSKASKSSKGKDGVEVEAPSRKR 572
+ + +A + E + +P P+P+ K P K AP+ K
Sbjct: 423 TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKE---------PAPTTK- 472
Query: 573 KLSPGPTTLKRTCILEPTGKGKPSGCRGLSAKTKTALSMGLNGTMGP---RVKRAGPLDC 629
P PTT K PT KP+ T T P K P
Sbjct: 473 --EPAPTTPKEPA---PTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTT 527
Query: 630 RGSPHQLPTPVKASQLENRGAAGHPAKALPTNCLSEEEVAKKRKNLATYCRPVKA--KHC 687
+ +P P + + A P + PT K T +P K
Sbjct: 528 KSAPTTTKEPAPTT---TKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEP 584
Query: 688 QAGAPADVACSVRRKKPGPALAFEEKCSTLKSKA 721
P + A KKP P E +T K A
Sbjct: 585 APTTPKEPA-PTTTKKPAPTTPKEPAPTTPKETA 617
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 44.3 bits (103), Expect = 4e-04
Identities = 75/289 (25%), Positives = 100/289 (34%), Gaps = 57/289 (19%)
Query: 346 RSRASSESELDDEGPCGGDGDPGL------------FPFPMPRGGTQASSEESEEEGTSD 393
RS S+ + D GP G P + P P P + +E + +S
Sbjct: 153 RSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSA 212
Query: 394 DLHPPPDCHYATRPPRPQAFCTFGSRLVSPGCYVFSRRLDRFCSALSSMLER-------- 445
H + A R RP A G L P SR L + LSS
Sbjct: 213 SEHSTTEPSPAARR-RPSA----GGGLQRPA----SRSLSSSATPLSSPARSGPSARGTP 263
Query: 446 ----HLSTHMWKKI----PPAAEPPAH--------LVNSPLSAPLSPSSTGTCPRLPGPT 489
H S K + PP PP L +SPL+ P SPS T P P
Sbjct: 264 RAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATP-SPSGTKARPVPPPDN 322
Query: 490 LRPACPASMPPTKDNLVPSYPAGSPSVAAACSQAECMGGSQAITSPLPANTPS--PSFSK 547
PA++PP+ P P PS +A S Q + SP PA PS P
Sbjct: 323 AATPLPATLPPSPPLATP-LPLAPPSPSAPPS-------LQTLPSP-PATPPSQAPPSMT 373
Query: 548 LPPSKASKSSKGKDGVEVEAPSRKRKLSPGPTTLKRTCILEPTGKGKPS 596
PP +A S + ++V L P+ L + + T G P+
Sbjct: 374 TPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPT 422
Score = 44.3 bits (103), Expect = 4e-04
Identities = 73/282 (25%), Positives = 95/282 (33%), Gaps = 41/282 (14%)
Query: 294 SPKEKSPGRKEQVLERPSQELPSSVQVVAAVAAPSSTFSVRAKQTYPYCALPRSRASSES 353
SP P + + P + P S+Q + + P S S + AL +A++
Sbjct: 359 SPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSL 418
Query: 354 ELDDEGPCGGDGDPGL-----FPFPMPRGGTQASSEESEEEGTSDDLHPPPDCHYA--TR 406
G P L F PR TQAS ++ PP +
Sbjct: 419 -----------GSPTLQATHSFLTMSPRQ-TQASLTSPSRPASTPPDSPPLQAPLSLPAS 466
Query: 407 PPRPQAFCTFGSRLVSPGCYVFSRRLDRFCS-----ALSSMLERHLSTHMWKKIPPAAEP 461
PP + S L SP + L S LSS++ L T P P
Sbjct: 467 PPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTP 526
Query: 462 PAHLVNSPLS-------APLSPSSTG-TCPRLPGPTLRPACPASMPPTKDNLVPSYPAGS 513
PA L PL PL +S T P L P CP PP+ P P
Sbjct: 527 PASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPP--PETP 584
Query: 514 PSVAAACSQAECMGGSQAITSPLPANTPSPSFSKL--PPSKA 553
S+A QA A+ SP PSP S L PP +A
Sbjct: 585 SSIATPPPQA-----PPALASPPLQGLPSPPLSPLATPPPQA 621
Score = 42.0 bits (97), Expect = 0.002
Identities = 136/593 (22%), Positives = 201/593 (33%), Gaps = 86/593 (14%)
Query: 102 RHGPLSKLYGRAP--PPPPAPASSQKCH----------VVNGQGPACRAPGSTKTSSREK 149
R GP ++ RAP P P P Q GP +P +T + S
Sbjct: 254 RSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPS--- 310
Query: 150 GQGSRSRGHQPPEKTQKDNLCQPGGLTKDSPGKPPMAPP----SKEPPGRENIEIIPSEG 205
G+++R PP DN P L P PP+A P P +++ +PS
Sbjct: 311 --GTKARPVPPP-----DNAATP--LPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPP 361
Query: 206 SSHWAEG-----SPPEKEPSGTRLPPKTHRKMARKECDLNRQCGVINPETKKICTRLLTC 260
++ ++ +PP + P + P + L + + + T L +
Sbjct: 362 ATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSP 421
Query: 261 KIHSVHQRREVQGRAKDFDVLVAELKANSRKGESPKEKSPGRKEQVLERPSQELPSSVQV 320
+ + H + R A L + SR +P + P L+ P LP+S +
Sbjct: 422 TLQATHSFLTMSPRQTQ-----ASLTSPSRPASTPPDSPP------LQAPLS-LPASPPL 469
Query: 321 VAAVAAPSSTFSVRAKQTYPYCALPRSRASSESELDDEGPCGGDGDPGLFPFPMPRGGTQ 380
+++ S S P P SS + + P L MP TQ
Sbjct: 470 QTSLSPAVSPLSS------PLTIHPLQALSSLASHSPQAP--------LSSLIMPPLETQ 515
Query: 381 ASSEESEEEGTSDDLHPPPDCHYATRPPRPQAFCTFGSRLVSPGCYVFSRRLDRFC---S 437
+S + L PP + + P P T + L +P ++ + C +
Sbjct: 516 SSLAPPSLQTPPASLTTPPLENLPSLAPPPLQ--TASAPLTTP--HLETPPCPAPCPLQA 571
Query: 438 ALSSMLERHLSTHMWKKIPPAAEPPAHLVNSPL----SAPLSPSSTGTCPRLPGPTLRPA 493
S + T PP PPA L + PL S PLSP +T P+ P P
Sbjct: 572 PPSPLTTPPPETPSSIATPPPQAPPA-LASPPLQGLPSPPLSPLATPP-PQAPPXLALP- 628
Query: 494 CPASMPPTKDNLVPSYPAGSPSVAAACSQAECMGGSQAITSPLPANTPSPSFS--KLPPS 551
P PP+ P P +PS A + A + QA SP P+ FS PP
Sbjct: 629 -PLQAPPSPPASPPLSPLATPSPQAPNALAVHL--LQAPFSPPPSPPVQAPFSPPASPPV 685
Query: 552 KASKSSKGKDGVEVEAPSRKRKLSPGPTTLKRTCILEPTGKGKPSGCRGLSAKTKTALS- 610
S + + + AP + SP + P P L S
Sbjct: 686 SPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASP 745
Query: 611 -MGLNGTMGPRVK---RAGPLDCRGSPHQLPTPVKASQLENRGAAGHPAKALP 659
M + T PRV A PL SP P + S L PA A P
Sbjct: 746 PMSPSATPPPRVPPLLAAPPLQVPPSP---PASLPMSPLAKPPPQAPPALATP 795
Score = 40.4 bits (93), Expect = 0.006
Identities = 60/217 (27%), Positives = 80/217 (36%), Gaps = 18/217 (8%)
Query: 456 PPAAEPPAHLVNSP-LSAPLSPSSTG---TCPRLPGPTLR-PACPASMPPTKDNLVPSYP 510
P A PP + SP S P+SPS+T P L P L+ P P + PP + P P
Sbjct: 697 PSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPP-P 755
Query: 511 AGSPSVAAACSQAECMGGSQAITSPLPANTP-SPSFSKLPPSKASKSSKGK-DGVEVEAP 568
P +AA Q + SPL P +P PP +A S G +P
Sbjct: 756 RVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSP 815
Query: 569 SRKRKLSP--GPTTLKRTCILEPTGKGKPSGCRGLSAKTKTALSMGLNGTMGPRVKRAGP 626
S +SP P + P + PS + T + T GP +GP
Sbjct: 816 SASLPMSPLATPPPQAPPVLAAPLLQVPPS-----PPASPTLQAPRRPPTPGPDTSVSGP 870
Query: 627 ---LDCRGSPHQLPTPVKASQLENRGAAGHPAKALPT 660
L P P+ +S L AGH + A T
Sbjct: 871 RLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATST 907
Score = 30.0 bits (66), Expect = 7.9
Identities = 27/123 (21%), Positives = 38/123 (30%), Gaps = 8/123 (6%)
Query: 112 RAPPPPPAPASSQKCHVVNGQGPACRAPGSTKTSSREKGQGSRSRGHQPPEKTQKDNLCQ 171
+AP PPA Q P A + S PP +
Sbjct: 674 QAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP 733
Query: 172 PGGLTKDSPGKPPMAPPSKEPP------GRENIEIIPSEGSSHWAE--GSPPEKEPSGTR 223
P + P PPM+P + PP +++ PS +S PP + P
Sbjct: 734 PLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALA 793
Query: 224 LPP 226
PP
Sbjct: 794 TPP 796
>gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]
Length = 638
Score = 44.3 bits (103), Expect = 4e-04
Identities = 81/346 (23%), Positives = 111/346 (32%), Gaps = 52/346 (15%)
Query: 260 CKIHSVHQRREVQGRA---KDFDVLVAELKANSRKGESPKEKSPGRKEQVLERPSQELPS 316
CK + Q +A K++ L+AEL GE+P S G P P
Sbjct: 292 CKFQRPGDPQSAQDKARMDKEYLSLMAEL------GEAPVPASVGSTSGPATTPLASAPR 345
Query: 317 SVQVVAAVAAPSSTFSVRAKQTYPYCALPRSRASSESELDDEGPCGGDGDPGLFPFPMP- 375
PS + +++ P+ S + + GP G G P FP P+P
Sbjct: 346 PAAPANNPPPPSLMSTTQSRP--PWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPS 403
Query: 376 -RGGTQASSEESEEEGTSDD--LHPPPDCHYATRPP----RPQAFCTFGSRLVSPGCYVF 428
GG + G PPP + PP P GS V G Y
Sbjct: 404 LTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRL 463
Query: 429 SRRLDRFCSALSSMLERHLSTHMWKKIPPAAEPPAHLVNSPLSAPLSP--SSTGTCPRLP 486
+ M+ PP PP+ P S PL P P P
Sbjct: 464 HQGKGMMPPPPMGMM------------PPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPP 511
Query: 487 GPTLRPACPASMPPTKDNLVPSYPAGSPSV---------AAACSQAECMGGS-------Q 530
P+ A +P ++ + AG+ S+ AAA A M G+
Sbjct: 512 PPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPP 571
Query: 531 AITSPLPANTPSPSFSKLPPSKASK--SSKGKDGVEVEAPSRKRKL 574
+ PLP P P PP A +G DG E+ R L
Sbjct: 572 GVQPPLPPGAPPPP-PPPPPGSAGMMIPPRGGDGPSHESEDFPRPL 616
Score = 35.8 bits (81), Expect = 0.14
Identities = 33/109 (30%), Positives = 40/109 (36%), Gaps = 10/109 (9%)
Query: 114 PPPPPAPASSQKCHV-VNGQGPACRAPGSTKTSSREKGQGSRSRGHQPPEKTQKDN---- 168
PPPPP P+SS + Q S T S Q ++ P Q
Sbjct: 507 PPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTM 566
Query: 169 -LCQPGGLTKDSPGKPPMAPPSKEPPGRENIEIIP--SEGSSHWAEGSP 214
PG PG PP PP PPG + I P +G SH +E P
Sbjct: 567 VPLPPGVQPPLPPGAPP--PPPPPPPGSAGMMIPPRGGDGPSHESEDFP 613
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 43.9 bits (102), Expect = 5e-04
Identities = 140/604 (23%), Positives = 189/604 (31%), Gaps = 96/604 (15%)
Query: 114 PPPPPAPASSQKCHVVNGQGPACRAP--------------------GSTKTSSRE-KGQG 152
PPPP PA+ + V+ G R P G T+TS G+G
Sbjct: 35 PPPPVTPAALR---VLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRPPASGRG 91
Query: 153 SRSRGHQPPEKTQKDNLCQPG---GLTKDSP-GKPPMAPPSKEPPGRENIEIIPSEGSSH 208
R+ P + T + PG G T+ P G+ + ++E R P +
Sbjct: 92 ERA---PPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALS 148
Query: 209 WAEGSPPEKEPSGTRLPPKTHR-KMARKECDLNRQCGVINPETKKICTRLLTCKIHSVHQ 267
GT P R + A E L R P R S H
Sbjct: 149 AGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSA-SEHS 207
Query: 268 RREVQGRAKDFDVLVAELKANSRKG--ESPKEKSPGRKEQVLERPSQELPSSVQVVAAVA 325
E A+ + S G + P +S L P++ PS+ A A
Sbjct: 208 TTEPSPAAR---------RRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPA 258
Query: 326 APSSTF-----SVRAKQTYP--YCALPRSRASSESEL---DDEGPCGGDGDPGLFPFPMP 375
PS ++R Q P A P S S L P P L P P
Sbjct: 259 HPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSP 318
Query: 376 RGGTQASSEESEEEGTSDDLHP----PPDCHYATRPPR-PQAFCTFGSRLVSPGCYVFSR 430
+ + S T H PP AT PP+ P A L +P S
Sbjct: 319 PATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALAL--PPLQAPPSPPASP 376
Query: 431 RLDRFCSALSSMLERHLSTHMWKK--IPPAAEPPAHLVNSPLSAPLSPSSTGTC---PRL 485
L + S L+ H+ + PP + P + P S P+SPS+T P L
Sbjct: 377 PLSPLATP-SPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSL 435
Query: 486 PGPTLR-PACPASMPPTKDNLVPSYPAGSPSVAAACSQAECMGGSQAITSPLPANTP--- 541
P L+ P P + PP + P P P +AA Q + P P P
Sbjct: 436 AAPPLQVPPSPPASPPMSPSATPP-PQAPPPLAAPPLQ---------LAKPPPQAPPALA 485
Query: 542 SPSFSKLPPSKASKSSKGKDGVEVEAPSRKRKLSP--GPTTLKRTCILEPTGKGKPSGCR 599
+P LP AS + P P P L + P P
Sbjct: 486 TPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPP---SPPASP 542
Query: 600 GLSAKTKTALSMGLNGTMGPRVKRAGP---LDCRGSPHQLPTPVKASQLENRGAAGHPAK 656
L A + T GP +GP L P P+ +S L AGH +
Sbjct: 543 TLQAPRRPP-------TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSS 595
Query: 657 ALPT 660
A T
Sbjct: 596 ATST 599
Score = 33.1 bits (74), Expect = 0.93
Identities = 105/458 (22%), Positives = 143/458 (31%), Gaps = 72/458 (15%)
Query: 172 PGGLTKDSPGKPPMAPPSKEPPGRENIEIIPSEGSSHWAE-----------GSPPEKEPS 220
PG LT PG P PP P + + G AE S P P+
Sbjct: 22 PGLLTPRPPGS-PRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPT 80
Query: 221 GTRLPPKTHRKMARKECDLNRQCGVINPETKKICTRLLTCKIHSVHQRREVQGRAKDFDV 280
T PP + R G P K ++ + R K +
Sbjct: 81 RTSRPPASGR-------------GERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRI 127
Query: 281 LVAELKANSRKGESPKEK--SPGRKEQVLERPSQELPSSVQVVAAVAAPSSTFSVR---A 335
E A + E+PK S G + P+ PS + AA + R +
Sbjct: 128 SAEETVARGKATEAPKRSALSAGARRDT-SGPTPGTPSPAMARRSRAAGTEVGLPRPAPS 186
Query: 336 KQTYPYCALPRSRASSESELDDEGPCGGDGDPGLFPFPMPRGGTQASSEESEEEGTSDDL 395
+ P PR SS SE P P P GG Q + S +
Sbjct: 187 ARPRPPTEGPRKSVSSASEHSTTEP-----SPAARRRPSAGGGLQRPASRSLSSSATPLS 241
Query: 396 HPPPDCHYATRPPRPQAFCT----FGSRLVSPGCYVFSRRLDRFCSALSSMLERHLSTHM 451
P A PR A + G + + P V R D AL + L+T
Sbjct: 242 SPARSGPSARGTPRAPAHPSQPKPKGLQALRPP-QVTPPRKDA-APALGPLSSSPLATPS 299
Query: 452 WKKIP-PAAEPPAHLVNSPLSAPLSPSST--------GTCPRLPGPTLRPAC-------- 494
P P+A P + SP + P S ++T T LP P L P
Sbjct: 300 PSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPP 359
Query: 495 -----PASMPPTKDNLVPSYPAGSPSVAAACSQAECM-------GGSQAITSPL-PANTP 541
P PP+ P P +PS A + A + S + +P P +P
Sbjct: 360 ALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP 419
Query: 542 SPSFSKLPPSKASKSSKGKDGVEVEAPSRKRKLSPGPT 579
S S PPS+A S +P +SP T
Sbjct: 420 PVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSAT 457
>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
Length = 3230
Score = 43.9 bits (102), Expect = 5e-04
Identities = 68/268 (25%), Positives = 96/268 (35%), Gaps = 39/268 (14%)
Query: 455 IPPAAEPPAHLVNSPLSAPLSPSSTGTCPRLPGPTLRPA-CPASMPPTKDNLVPSYPAGS 513
+ PA PP+ S L A L+P T T RLP PTL A P P L+ + S
Sbjct: 1327 LAPAPRPPS----SGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLVRPLLKLVHSPS 1382
Query: 514 PSVAAACSQAECMGGSQAITSPL--PANTPSPSFSKLP---------PSKASKSSKGKDG 562
P V+A+ A + I+SPL P++ P P+ S +P P ++ S
Sbjct: 1383 PEVSASAPGAAPL----TISSPLHVPSSLPGPASSPMPIPNSSPLASPVSSTVSVPLSSS 1438
Query: 563 VEVEAPSRKRKLSPGPTTLKRTCILEPTGKGKPSGCRGLSAKTKTALSMGLNGTMGPRVK 622
+ + P+ + P T+ + L + G L L+ + GP
Sbjct: 1439 LPISVPTTLPAPASAPLTIPISAPLTVSASGP-----ALLTSVTPPLAPVVPAAPGP--P 1491
Query: 623 RAGPLDCRGSPHQLPTPV-KASQLENRGAAGHPAKALPTNCLSEEEVAKKRKNLATYCRP 681
P S L + A L + GHP PT+ V +A C P
Sbjct: 1492 SLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTS----SHVPGLNSTVAPACSP 1547
Query: 682 VKAKHCQAGAPADVACSVRRKKPGPALA 709
V PA S P PA A
Sbjct: 1548 VL-------VPASALASPFPSAPNPAPA 1568
Score = 38.9 bits (89), Expect = 0.017
Identities = 48/168 (28%), Positives = 65/168 (38%), Gaps = 31/168 (18%)
Query: 456 PPAAEPPAHLVNSPLS-AP-LSPSSTGTCPRLPGPT----------LRPACPASMPPTKD 503
P A P A + L+ AP LS S T P L PT + PAC + P
Sbjct: 1495 PSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAPACSPVLVPASA 1554
Query: 504 NLVPSYPAGSPSVAAACSQAECMGGSQAITSPLP----------ANTPSPSFSKLP---- 549
P A +P+ A A A SQA+ +PL A +P+P + LP
Sbjct: 1555 LASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSPAPPLAPLPVLAP 1614
Query: 550 -PSKASKSSKGKDGVEVEAPSRKRKLSPGPTTLKRTCILEPTGKGKPS 596
P A + + V V APS +PG + + + PT PS
Sbjct: 1615 SPGAAPVLASSQTPVPVMAPSS----TPGTSLASASPVPAPTPVLAPS 1658
Score = 36.2 bits (82), Expect = 0.11
Identities = 35/126 (27%), Positives = 48/126 (38%), Gaps = 26/126 (20%)
Query: 457 PAAEPPAHLVNSPLSAPLSPSSTGTCPRLPGP------TLRPACPA----SMPPTKDNLV 506
PA+ PP + L PL P+S LP P T RP P PP L
Sbjct: 1062 PASRPPGPV----LLPPLQPNSGSLPQVLPSPLGVLSGTSRPPTPTLSLKPTPPAPVRLS 1117
Query: 507 PSYPAGSPSVAA------------ACSQAECMGGSQAITSPLPANTPSPSFSKLPPSKAS 554
P+ P GS S+ A + + A T+ +PA TP+P L P +
Sbjct: 1118 PAPPPGSSSLLKPLTVPPGYTFPPAAATTTSTTTATATTTAVPAPTPAPQRLILSPDMQA 1177
Query: 555 KSSKGK 560
+ G+
Sbjct: 1178 RLPSGE 1183
Score = 32.7 bits (73), Expect = 1.2
Identities = 51/208 (24%), Positives = 72/208 (34%), Gaps = 40/208 (19%)
Query: 462 PAHLVNSPLSAPLSPSS---TGTCPRLPGPTLRPACPASMPPTKDNLVPSYPAGSPSVAA 518
PA + L+ PL+P + T P P L P + P ++ S P +A
Sbjct: 1575 PASSASQALATPLAPMAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAP 1634
Query: 519 ACSQAECMGGSQAITSPLPANTPSPSFSKLPPSKASKSSKGKDGVEVEAPSRKRKLSPGP 578
+ + + + + +P P PS + + LP AP SP
Sbjct: 1635 SSTPGTSLASASPVPAPTPVLAPSSTQTMLP-----------------APVPSPLPSPAS 1677
Query: 579 T-TLKRTCILEPT-GKGKPSGCRGLSAKTKTALSMGLNGTMGPRVKRAGPLDCRGSPHQL 636
T TL L PT G PS LS+G GP + L + +
Sbjct: 1678 TQTLALAPALAPTLGGSSPS----------QTLSLGTGNPQGPFPTQT--LSLTPASSLV 1725
Query: 637 PTPVKASQLENRGAAGHPAKALPTNCLS 664
PTP + L A G P PT LS
Sbjct: 1726 PTPAQTLSL----APGPPLG--PTQTLS 1747
>gi|50345997 E1A binding protein p300 [Homo sapiens]
Length = 2414
Score = 43.5 bits (101), Expect = 7e-04
Identities = 31/92 (33%), Positives = 41/92 (44%), Gaps = 8/92 (8%)
Query: 466 VNSPLSAPLSPSSTGTCPRLPGPTLRPACPASMP---PTKDNLVPSYPAGSP---SVAAA 519
VNSP+ P S S CP+LP P L P+ +P PT + PS A P ++ A
Sbjct: 803 VNSPIMPPGSQGSHIHCPQLPQPALHQNSPSPVPSRTPTPHHTPPSIGAQQPPATTIPAP 862
Query: 520 CSQAECM--GGSQAITSPLPANTPSPSFSKLP 549
M G P P TP+P ++LP
Sbjct: 863 VPTPPAMPPGPQSQALHPPPRQTPTPPTTQLP 894
Score = 33.9 bits (76), Expect = 0.54
Identities = 30/108 (27%), Positives = 48/108 (44%), Gaps = 11/108 (10%)
Query: 458 AAEPPAHLVNSPL-SAPLSPSSTGTCPRLPGPTLRPACPASMPPTKDNLVPSYPAGSPSV 516
A +PPA + +P+ + P P + P P P P + P + + PS PA
Sbjct: 851 AQQPPATTIPAPVPTPPAMPPGPQSQALHPPPRQTPTPPTTQLPQQ--VQPSLPA----- 903
Query: 517 AAACSQAECMGGSQAITSPLPANTPSPSFSKLPPSKASKSSKGKDGVE 564
A + Q + SQ T+ A+ P+P+ LPP A+ S+ +E
Sbjct: 904 APSADQPQQQPRSQQSTA---ASVPTPTAPLLPPQPATPLSQPAVSIE 948
>gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]
Length = 639
Score = 43.1 bits (100), Expect = 9e-04
Identities = 76/324 (23%), Positives = 105/324 (32%), Gaps = 45/324 (13%)
Query: 260 CKIHSVHQRREVQGRA---KDFDVLVAELKANSRKGESPKEKSPGRKEQVLERPSQELPS 316
CK + Q +A K++ L+AEL GE+P S G P P
Sbjct: 292 CKFQRPGDPQSAQDKARMDKEYLSLMAEL------GEAPVPASVGSTSGPATTPLASAPR 345
Query: 317 SVQVVAAVAAPSSTFSVRAKQTYPYCALPRSRASSESELDDEGPCGGDGDPGLFPFPMP- 375
PS + +++ P+ S + + GP G G P FP P+P
Sbjct: 346 PAAPANNPPPPSLMSTTQSRP--PWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPS 403
Query: 376 -RGGTQASSEESEEEGTSDD--LHPPPDCHYATRPP----RPQAFCTFGSRLVSPGCYVF 428
GG + G PPP + PP P GS V G Y
Sbjct: 404 LTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRL 463
Query: 429 SRRLDRFCSALSSMLERHLSTHMWKKIPPAAEPPAHLVNSPLSAPLSP--SSTGTCPRLP 486
+ M+ PP PP+ P S PL P P P
Sbjct: 464 HQGKGMMPPPPMGMM------------PPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPP 511
Query: 487 GPTLRPACPASMPPTKDNLVPSYPAGSPSV---------AAACSQAECMGGSQAITSPLP 537
P+ A +P ++ + AG+ S+ AAA A M G+ + PLP
Sbjct: 512 PPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMV-PLP 570
Query: 538 --ANTPSPSFSKLPPSKASKSSKG 559
P P + PP S G
Sbjct: 571 PGVQPPLPPGAPPPPPPPPPGSAG 594
Score = 30.8 bits (68), Expect = 4.6
Identities = 30/114 (26%), Positives = 38/114 (33%), Gaps = 23/114 (20%)
Query: 114 PPPPPAPASSQKCHVVNGQGPACRAPGSTKTSSREKGQGSRSRGHQPPEKTQKDNLCQPG 173
PPPPP P+SS +T T++ G GS P ++ Q PG
Sbjct: 507 PPPPPPPSSSM------ASSTPLPWQQNTTTTTTSAGTGS----IPPWQQQQAAAAASPG 556
Query: 174 G--------LTKDSPGKPPMAPPSKEPPGRENIEIIPSEGSSHWAEGSPPEKEP 219
+ PG P PP PP P GS+ PP P
Sbjct: 557 APQMQGNPTMVPLPPGVQPPLPPGAPPPPPP-----PPPGSAGMMYAPPPPPPP 605
>gi|110611908 mitogen-activated protein kinase kinase kinase kinase
1 isoform 1 [Homo sapiens]
Length = 821
Score = 42.7 bits (99), Expect = 0.001
Identities = 39/156 (25%), Positives = 49/156 (31%), Gaps = 18/156 (11%)
Query: 99 CERRHGPLSKLYGRAPPPPPAPASSQKCHVVNGQGPACR---------------APGSTK 143
C RRH KL G PP A Q + P + P
Sbjct: 334 CCRRHMEFRKLRGMETRPPANTARLQPPRDLRSSSPRKQLSESSDDDYDDVDIPTPAEDT 393
Query: 144 TSSREKGQGSRSRGHQPPEKTQKDNLCQPGGLTKDSPGKPPMAPPSKEPPGRENIEIIPS 203
RS + P D PG L + + G PP +P PP + +
Sbjct: 394 PPPLPPKPKFRSPSDEGPGSMGDDGQLSPGVLVRCASGPPPNSPRPGPPPSTSSPHLTAH 453
Query: 204 EGSSHWAEGSPPEKEPSGTRLPPKTHRKMARKECDL 239
S W +PP +E L P KM RK C L
Sbjct: 454 SEPSLW---NPPSRELDKPPLLPPKKEKMKRKGCAL 486
>gi|6005810 mitogen-activated protein kinase kinase kinase kinase 1
isoform 2 [Homo sapiens]
Length = 833
Score = 42.7 bits (99), Expect = 0.001
Identities = 39/156 (25%), Positives = 49/156 (31%), Gaps = 18/156 (11%)
Query: 99 CERRHGPLSKLYGRAPPPPPAPASSQKCHVVNGQGPACR---------------APGSTK 143
C RRH KL G PP A Q + P + P
Sbjct: 334 CCRRHMEFRKLRGMETRPPANTARLQPPRDLRSSSPRKQLSESSDDDYDDVDIPTPAEDT 393
Query: 144 TSSREKGQGSRSRGHQPPEKTQKDNLCQPGGLTKDSPGKPPMAPPSKEPPGRENIEIIPS 203
RS + P D PG L + + G PP +P PP + +
Sbjct: 394 PPPLPPKPKFRSPSDEGPGSMGDDGQLSPGVLVRCASGPPPNSPRPGPPPSTSSPHLTAH 453
Query: 204 EGSSHWAEGSPPEKEPSGTRLPPKTHRKMARKECDL 239
S W +PP +E L P KM RK C L
Sbjct: 454 SEPSLW---NPPSRELDKPPLLPPKKEKMKRKGCAL 486
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 42.7 bits (99), Expect = 0.001
Identities = 62/254 (24%), Positives = 91/254 (35%), Gaps = 46/254 (18%)
Query: 456 PPAAEPPAHLVNSPLSAPLSPSSTGTCPRLPGPTLRPACPASMPPTKDNLVPSYPAGSPS 515
P +EP + PL P+ P TG GP P + P L P P+
Sbjct: 1391 PTFSEP-----SGPLLLPVCPLPTGRRDERSGPLASPVLLETGLPLPLPLPLPLPLALPA 1445
Query: 516 VAAACSQAECMGGSQAITSPLPANTPSPSFSKLPPSKASKSSKGKDGVEVEAPSRKRKLS 575
V A ++A +PLP P+P S PP K P R R+
Sbjct: 1446 VLRAQARA---------PTPLPPLLPAPLASCPPPMK-------------RKPGRPRRSP 1483
Query: 576 PGPTTLKRTCILEPTGKGKPSGCRGLSAKTKTALSMGLNGTMGPRV-----KRAG----- 625
P +L + P G L + +T + T PR + AG
Sbjct: 1484 PSMLSLDGPLVRPPAGAALGRELLLLPGQPQTPV---FPSTHDPRTVTLDFRNAGIPAPP 1540
Query: 626 -PLDCRGSPHQLPTPVKASQLENRGAAGH-PAKALPTNCLSEEEVAKKRKNLA----TYC 679
PL + P P PV+ ++L + P++A+P +EV ++ LA +
Sbjct: 1541 PPLPPQPPPPPPPPPVEPTKLPFKELDNQWPSEAIPPGPRGRDEVTEEYMELAKSRGPWR 1600
Query: 680 RPVKAKHCQAGAPA 693
RP K +H PA
Sbjct: 1601 RPPKKRHEDLVPPA 1614
Score = 33.1 bits (74), Expect = 0.93
Identities = 26/84 (30%), Positives = 40/84 (47%), Gaps = 8/84 (9%)
Query: 114 PPPPPAPASSQKCHV--VNGQGPACRAPGSTKTS---SREKGQGSRSRG--HQPPEKTQK 166
PPPPP P K ++ Q P+ P + + E + ++SRG +PP+K +
Sbjct: 1549 PPPPPPPVEPTKLPFKELDNQWPSEAIPPGPRGRDEVTEEYMELAKSRGPWRRPPKKRHE 1608
Query: 167 DNLCQPGGLTKDSPGKPPMAPPSK 190
D L P G + SP +P P S+
Sbjct: 1609 D-LVPPAGSPELSPPQPLFRPRSE 1631
Score = 30.8 bits (68), Expect = 4.6
Identities = 56/205 (27%), Positives = 69/205 (33%), Gaps = 30/205 (14%)
Query: 456 PPAAEPPAHLVNSPLSAP-----LSPSSTGTCP---RLPGPTLRPACPASMPPTKDNLVP 507
PPA E A SP AP + P P + P P RP P S PP +
Sbjct: 1243 PPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDA 1302
Query: 508 SYPAGSPSVAAACSQAECMGGSQAITSPLPANTPSPSFSKLPP-----SKASKSSKGKDG 562
S+P+ P A G ++ T + PP S S SS G
Sbjct: 1303 SHPSVPPEPLAEDHPPHTPGLCGSLAKSQSTETVPATPGGEPPLSGGSSGLSLSSPQVPG 1362
Query: 563 VEVEAPSRKRKLSPG--PTTLKRTCILEPTGKGKPSGCRGLSAKTKTALSMGLNGTMGPR 620
P+ LS G P T R PT +PSG L G R
Sbjct: 1363 SPFSYPAPSPSLSSGGLPRTPGRDFSFTPT-FSEPSGPLLLPVCPLPT---------GRR 1412
Query: 621 VKRAGPLDC-----RGSPHQLPTPV 640
+R+GPL G P LP P+
Sbjct: 1413 DERSGPLASPVLLETGLPLPLPLPL 1437
Score = 30.4 bits (67), Expect = 6.0
Identities = 36/130 (27%), Positives = 44/130 (33%), Gaps = 20/130 (15%)
Query: 107 SKLYGRAPPPPPA-PASSQKCHVVNGQGPACRAPGSTKTSSREKGQGSRSRGH-----QP 160
S + PPP A PA K Q P P + + G+R G P
Sbjct: 375 SATFAHTPPPAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFGARDSGEFRRAPAP 434
Query: 161 PEKTQKDNLCQPGGLTKDSPGKPPMAPP----SKEPPGRENIEIIPSEGSSHWAEGSPP- 215
P + L K+ PG PP PP S E GR P S G+P
Sbjct: 435 PPLPPAEPLA------KEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDS---PGTPTL 485
Query: 216 EKEPSGTRLP 225
E P+G P
Sbjct: 486 ESSPAGPEKP 495
Score = 30.4 bits (67), Expect = 6.0
Identities = 24/74 (32%), Positives = 33/74 (44%), Gaps = 9/74 (12%)
Query: 565 VEAPSRKRKLSPGPTTLKRTCILEPTGKGKPSGCRGLSAKTKTALSMGLNGTM---GPRV 621
V++ K + P P +C+LE GKG+ G GL L +GL G + +V
Sbjct: 911 VKSGEHKDEDRPKPKDRIASCLLESWGKGEGLGYEGL------GLGIGLRGAIRLPSFKV 964
Query: 622 KRAGPLDCRGSPHQ 635
KR P D S Q
Sbjct: 965 KRKEPPDTTSSGDQ 978
>gi|24497538 homeobox C4 [Homo sapiens]
Length = 264
Score = 42.4 bits (98), Expect = 0.002
Identities = 25/80 (31%), Positives = 35/80 (43%), Gaps = 14/80 (17%)
Query: 114 PPPPPAPASSQKCHVVNG-QGPACRAPGSTKTSSREKGQGSRSRGHQPPEKTQKDNLCQP 172
PPPPP P+ ++ + QGP +G G GH PEK+Q +LC+P
Sbjct: 54 PPPPPRPSYPERQYSCTSLQGPG-----------NSRGHGPAQAGHHHPEKSQ--SLCEP 100
Query: 173 GGLTKDSPGKPPMAPPSKEP 192
L+ S P P +P
Sbjct: 101 APLSGASASPSPAPPACSQP 120
>gi|24497540 homeobox C4 [Homo sapiens]
Length = 264
Score = 42.4 bits (98), Expect = 0.002
Identities = 25/80 (31%), Positives = 35/80 (43%), Gaps = 14/80 (17%)
Query: 114 PPPPPAPASSQKCHVVNG-QGPACRAPGSTKTSSREKGQGSRSRGHQPPEKTQKDNLCQP 172
PPPPP P+ ++ + QGP +G G GH PEK+Q +LC+P
Sbjct: 54 PPPPPRPSYPERQYSCTSLQGPG-----------NSRGHGPAQAGHHHPEKSQ--SLCEP 100
Query: 173 GGLTKDSPGKPPMAPPSKEP 192
L+ S P P +P
Sbjct: 101 APLSGASASPSPAPPACSQP 120
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.129 0.396
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,989,047
Number of Sequences: 37866
Number of extensions: 2490710
Number of successful extensions: 15978
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 70
Number of HSP's successfully gapped in prelim test: 888
Number of HSP's that attempted gapping in prelim test: 12295
Number of HSP's gapped (non-prelim): 4236
length of query: 722
length of database: 18,247,518
effective HSP length: 110
effective length of query: 612
effective length of database: 14,082,258
effective search space: 8618341896
effective search space used: 8618341896
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.