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Search of human proteins with 92110010
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|92110010 GRAM domain containing 1A isoform 1 [Homo sapiens]
(724 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|92110010 GRAM domain containing 1A isoform 1 [Homo sapiens] 1462 0.0
gi|209969686 GRAM domain containing 1A isoform 2 [Homo sapiens] 1425 0.0
gi|144227752 GRAM domain containing 1B [Homo sapiens] 634 0.0
gi|187936935 GRAM domain containing 1C [Homo sapiens] 438 e-123
gi|226443028 GRAM domain containing 3 isoform 5 [Homo sapiens] 106 9e-23
gi|226443011 GRAM domain containing 3 isoform 1 [Homo sapiens] 106 9e-23
gi|226443007 GRAM domain containing 3 isoform 2 [Homo sapiens] 106 9e-23
gi|226443022 GRAM domain containing 3 isoform 4 [Homo sapiens] 104 3e-22
gi|226443017 GRAM domain containing 3 isoform 3 [Homo sapiens] 100 4e-21
gi|60593095 GRAM domain containing 2 [Homo sapiens] 92 2e-18
gi|139394668 TBC1 domain family, member 9 (with GRAM domain) [Ho... 65 3e-10
gi|38570103 TBC1 domain family, member 8B (with GRAM domain) iso... 62 2e-09
gi|38570101 TBC1 domain family, member 8B (with GRAM domain) iso... 62 2e-09
gi|45597177 TBC1 domain family, member 9B (with GRAM domain) iso... 59 2e-08
gi|45597175 TBC1 domain family, member 9B (with GRAM domain) iso... 59 2e-08
gi|156231067 TBC1 domain family, member 8 [Homo sapiens] 48 3e-05
gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax ... 39 0.013
gi|113204617 skeletal muscle ryanodine receptor isoform 2 [Homo ... 39 0.022
gi|113204615 skeletal muscle ryanodine receptor isoform 1 [Homo ... 39 0.022
gi|46560555 transmembrane protein 132E [Homo sapiens] 38 0.029
gi|34304354 phosphatase and actin regulator 3 isoform 2 [Homo sa... 37 0.049
gi|18087853 phosphatase and actin regulator 3 isoform 1 [Homo sa... 37 0.049
gi|151101459 SAPS domain family, member 1 [Homo sapiens] 37 0.049
gi|154146199 sal-like 3 [Homo sapiens] 37 0.064
gi|38201677 teashirt family zinc finger 1 [Homo sapiens] 37 0.064
gi|163310725 ER degradation enhancer, mannosidase alpha-like 3 [... 37 0.064
gi|223468617 family with sequence similarity 75, member C1 [Homo... 37 0.084
gi|56549117 dynamin 1 isoform 2 [Homo sapiens] 36 0.14
gi|59853099 dynamin 1 isoform 1 [Homo sapiens] 36 0.14
gi|29789008 Huntingtin interacting protein C isoform 2 [Homo sap... 36 0.14
>gi|92110010 GRAM domain containing 1A isoform 1 [Homo sapiens]
Length = 724
Score = 1462 bits (3784), Expect = 0.0
Identities = 724/724 (100%), Positives = 724/724 (100%)
Query: 1 MFDTTPHSGRSTPSSSPSLRKRLQLLPPSRPPPEPEPGTMVEKGSDSSSEKGGVPGTPST 60
MFDTTPHSGRSTPSSSPSLRKRLQLLPPSRPPPEPEPGTMVEKGSDSSSEKGGVPGTPST
Sbjct: 1 MFDTTPHSGRSTPSSSPSLRKRLQLLPPSRPPPEPEPGTMVEKGSDSSSEKGGVPGTPST 60
Query: 61 QSLGSRNFIRNSKKMQSWYSMLSPTYKQRNEDFRKLFSKLPEAERLIVDYSCALQREILL 120
QSLGSRNFIRNSKKMQSWYSMLSPTYKQRNEDFRKLFSKLPEAERLIVDYSCALQREILL
Sbjct: 61 QSLGSRNFIRNSKKMQSWYSMLSPTYKQRNEDFRKLFSKLPEAERLIVDYSCALQREILL 120
Query: 121 QGRLYLSENWICFYSNIFRWETTISIQLKEVTCLKKEKTAKLIPNAIQICTESEKHFFTS 180
QGRLYLSENWICFYSNIFRWETTISIQLKEVTCLKKEKTAKLIPNAIQICTESEKHFFTS
Sbjct: 121 QGRLYLSENWICFYSNIFRWETTISIQLKEVTCLKKEKTAKLIPNAIQICTESEKHFFTS 180
Query: 181 FGARDRCFLLIFRLWQNALLEKTLSPRELWHLVHQCYGSELGLTSEDEDYVSPLQLNGLG 240
FGARDRCFLLIFRLWQNALLEKTLSPRELWHLVHQCYGSELGLTSEDEDYVSPLQLNGLG
Sbjct: 181 FGARDRCFLLIFRLWQNALLEKTLSPRELWHLVHQCYGSELGLTSEDEDYVSPLQLNGLG 240
Query: 241 TPKEVGDVIALSDITSSGAADRSQEPSPVGSRRGHVTPNLSRASSDADHGAEEDKEEQVD 300
TPKEVGDVIALSDITSSGAADRSQEPSPVGSRRGHVTPNLSRASSDADHGAEEDKEEQVD
Sbjct: 241 TPKEVGDVIALSDITSSGAADRSQEPSPVGSRRGHVTPNLSRASSDADHGAEEDKEEQVD 300
Query: 301 SQPDASSSQTVTPVAEPPSTEPTQPDGPTTLGPLDLLPSEELLTDTSNSSSSTGEEADLA 360
SQPDASSSQTVTPVAEPPSTEPTQPDGPTTLGPLDLLPSEELLTDTSNSSSSTGEEADLA
Sbjct: 301 SQPDASSSQTVTPVAEPPSTEPTQPDGPTTLGPLDLLPSEELLTDTSNSSSSTGEEADLA 360
Query: 361 ALLPDLSGRLLINSVFHVGAERLQQMLFSDSPFLQGFLQQCKFTDVTLSPWSGDSKCHQR 420
ALLPDLSGRLLINSVFHVGAERLQQMLFSDSPFLQGFLQQCKFTDVTLSPWSGDSKCHQR
Sbjct: 361 ALLPDLSGRLLINSVFHVGAERLQQMLFSDSPFLQGFLQQCKFTDVTLSPWSGDSKCHQR 420
Query: 421 RVLTYTIPISNPLGPKSASVVETQTLFRRGPQAGGCVVDSEVLTQGIPYQDYFYTAHRYC 480
RVLTYTIPISNPLGPKSASVVETQTLFRRGPQAGGCVVDSEVLTQGIPYQDYFYTAHRYC
Sbjct: 421 RVLTYTIPISNPLGPKSASVVETQTLFRRGPQAGGCVVDSEVLTQGIPYQDYFYTAHRYC 480
Query: 481 ILGLARNKARLRVSSEIRYRKQPWSLVKSLIEKNSWSGIEDYFHHLERELAKAEKLSLEE 540
ILGLARNKARLRVSSEIRYRKQPWSLVKSLIEKNSWSGIEDYFHHLERELAKAEKLSLEE
Sbjct: 481 ILGLARNKARLRVSSEIRYRKQPWSLVKSLIEKNSWSGIEDYFHHLERELAKAEKLSLEE 540
Query: 541 GGKDARGLLSGLRRRKRPLSWRAHGDGPQHPDPDPCARAGIHTSGSLSSRFSEPSVDQGP 600
GGKDARGLLSGLRRRKRPLSWRAHGDGPQHPDPDPCARAGIHTSGSLSSRFSEPSVDQGP
Sbjct: 541 GGKDARGLLSGLRRRKRPLSWRAHGDGPQHPDPDPCARAGIHTSGSLSSRFSEPSVDQGP 600
Query: 601 GAGIPSALVLISIVICVSLIILIALNVLLFYRLWSLERTAHTFESWHSLALAKGKFPQTA 660
GAGIPSALVLISIVICVSLIILIALNVLLFYRLWSLERTAHTFESWHSLALAKGKFPQTA
Sbjct: 601 GAGIPSALVLISIVICVSLIILIALNVLLFYRLWSLERTAHTFESWHSLALAKGKFPQTA 660
Query: 661 TEWAEILALQKQFHSVEVHKWRQILRASVELLDEMKFSLEKLHQGITVSDPPFDTQPRPD 720
TEWAEILALQKQFHSVEVHKWRQILRASVELLDEMKFSLEKLHQGITVSDPPFDTQPRPD
Sbjct: 661 TEWAEILALQKQFHSVEVHKWRQILRASVELLDEMKFSLEKLHQGITVSDPPFDTQPRPD 720
Query: 721 DSFS 724
DSFS
Sbjct: 721 DSFS 724
>gi|209969686 GRAM domain containing 1A isoform 2 [Homo sapiens]
Length = 713
Score = 1425 bits (3689), Expect = 0.0
Identities = 713/724 (98%), Positives = 713/724 (98%), Gaps = 11/724 (1%)
Query: 1 MFDTTPHSGRSTPSSSPSLRKRLQLLPPSRPPPEPEPGTMVEKGSDSSSEKGGVPGTPST 60
MFDTTPHSGRSTPSSSPSLRKRLQLLPPSRPPPEPEPGTMVEKGSDSSSEKGGVPGTPST
Sbjct: 1 MFDTTPHSGRSTPSSSPSLRKRLQLLPPSRPPPEPEPGTMVEKGSDSSSEKGGVPGTPST 60
Query: 61 QSLGSRNFIRNSKKMQSWYSMLSPTYKQRNEDFRKLFSKLPEAERLIVDYSCALQREILL 120
QSLGSRNFIRNSK MLSPTYKQRNEDFRKLFSKLPEAERLIVDYSCALQREILL
Sbjct: 61 QSLGSRNFIRNSK-------MLSPTYKQRNEDFRKLFSKLPEAERLIVDYSCALQREILL 113
Query: 121 QGRLYLSENWICFYSNIFRWETTISIQLKEVTCLKKEKTAKLIPNAIQICTESEKHFFTS 180
QGRLYLSENWICFYSNIFRWETTISIQLKEVTCLKKEKTAKLIPNAIQICTESEKHFFTS
Sbjct: 114 QGRLYLSENWICFYSNIFRWETTISIQLKEVTCLKKEKTAKLIPNAIQICTESEKHFFTS 173
Query: 181 FGARDRCFLLIFRLWQNALLEKTLSPRELWHLVHQCYGSELGLTSEDEDYVSPLQLNGLG 240
FGARDRCFLLIFRLWQNALLEKTLSPRELWHLVHQCYGSELGLTSEDEDYVSPLQLNGLG
Sbjct: 174 FGARDRCFLLIFRLWQNALLEKTLSPRELWHLVHQCYGSELGLTSEDEDYVSPLQLNGLG 233
Query: 241 TPKEVGDVIALSDITSSGAADRSQEPSPVGSRRGHVTPNLSRASSDADHGAEEDKEEQVD 300
TPKEVGDVIALSDITSSGAADRSQEPSPVGSRRGHVTPNLSRASSDADHGAEEDKEEQVD
Sbjct: 234 TPKEVGDVIALSDITSSGAADRSQEPSPVGSRRGHVTPNLSRASSDADHGAEEDKEEQVD 293
Query: 301 SQPDASSSQTVTPVAEPPSTEPTQPDGPTTLGPLDLLPSEELLTDTSNSSSSTGEEADLA 360
SQPDASSSQTVTPVAEPPSTEPTQPDGPTTLGPLDLLPSEELLTDTSNSSSSTGEEADLA
Sbjct: 294 SQPDASSSQTVTPVAEPPSTEPTQPDGPTTLGPLDLLPSEELLTDTSNSSSSTGEEADLA 353
Query: 361 ALLPDLSGRLLINSVFHVGAERLQQMLFSDSPFLQGFLQQCKFTDVTLSPWSGDSKCHQR 420
ALLPDLSGRLLINSVFHVGAERLQQMLFSDSPFLQGFLQQCKFTDVTLSPWSGDSKCHQR
Sbjct: 354 ALLPDLSGRLLINSVFHVGAERLQQMLFSDSPFLQGFLQQCKFTDVTLSPWSGDSKCHQR 413
Query: 421 RVLTYTIPISNPLGPKSASVVETQTLFRRGPQAGGCVVDSEVLTQGIPYQDYFYTAHRYC 480
RVLTYTIPISNPLGPKSASVVETQTLFRRGPQAGGCVVDSEVLTQGIPYQDYFYTAHRYC
Sbjct: 414 RVLTYTIPISNPLGPKSASVVETQTLFRRGPQAGGCVVDSEVLTQGIPYQDYFYTAHRYC 473
Query: 481 ILGLARNKARLRVSSEIRYRKQPWSLVKSLIEKNSWSGIEDYFHHLERELAKAEKLSLEE 540
ILGLARNKARLRVSSEIRYRKQPWSLVKSLIEKNSWSGIEDYFHHLERELAKAEKLSLEE
Sbjct: 474 ILGLARNKARLRVSSEIRYRKQPWSLVKSLIEKNSWSGIEDYFHHLERELAKAEKLSLEE 533
Query: 541 GGKDARGLLSGLRRRKRPLSWRAHGDGPQHPDPDPCARAGIHTSGSLSSRFSEPSVDQGP 600
GGKDARGLLSGLRRRKRPLSWRAHGDGPQHPDPDPCARAGIHTSGSLSSRFSEPSVDQGP
Sbjct: 534 GGKDARGLLSGLRRRKRPLSWRAHGDGPQHPDPDPCARAGIHTSGSLSSRFSEPSVDQGP 593
Query: 601 GAGIPSALVLISIVICVSLIILIALNVLLFYRLWSLERTAHTFESWHSLALAKGKFPQTA 660
GAGIPSALVLISIV LIILIALNVLLFYRLWSLERTAHTFESWHSLALAKGKFPQTA
Sbjct: 594 GAGIPSALVLISIV----LIILIALNVLLFYRLWSLERTAHTFESWHSLALAKGKFPQTA 649
Query: 661 TEWAEILALQKQFHSVEVHKWRQILRASVELLDEMKFSLEKLHQGITVSDPPFDTQPRPD 720
TEWAEILALQKQFHSVEVHKWRQILRASVELLDEMKFSLEKLHQGITVSDPPFDTQPRPD
Sbjct: 650 TEWAEILALQKQFHSVEVHKWRQILRASVELLDEMKFSLEKLHQGITVSDPPFDTQPRPD 709
Query: 721 DSFS 724
DSFS
Sbjct: 710 DSFS 713
>gi|144227752 GRAM domain containing 1B [Homo sapiens]
Length = 738
Score = 634 bits (1634), Expect = 0.0
Identities = 347/731 (47%), Positives = 471/731 (64%), Gaps = 38/731 (5%)
Query: 4 TTPHSGRSTPSSSPSLRKRLQLLPPSRPPPEPEPG-TMVEKGSDSSSEKGGVPGTP---- 58
T +S RSTP+ SP LRKR + P P+ + G TMVEKGSD SS+K P TP
Sbjct: 9 TASNSNRSTPACSPILRKRSR-----SPTPQNQDGDTMVEKGSDHSSDKS--PSTPEQGV 61
Query: 59 --STQSLGSRNFIRNSKKMQSWYSMLSPTYKQRNEDFRKLFSKLPEAERLIVDYSCALQR 116
S S R+ +NSKK QSWY++LSPTYKQRNEDFRKLF +LP+ ERLIVDYSCALQR
Sbjct: 62 QRSCSSQSGRSGGKNSKKSQSWYNVLSPTYKQRNEDFRKLFKQLPDTERLIVDYSCALQR 121
Query: 117 EILLQGRLYLSENWICFYSNIFRWETTISIQLKEVTCLKKEKTAKLIPNAIQICTESEKH 176
+ILLQGRLYLSENWICFYSNIFRWET ++++LK++ + KEKTA+LIPNAIQ+CT+SEKH
Sbjct: 122 DILLQGRLYLSENWICFYSNIFRWETLLTVRLKDICSMTKEKTARLIPNAIQVCTDSEKH 181
Query: 177 FFTSFGARDRCFLLIFRLWQNALLEKTLSPRELWHLVHQCYGSELGLTSEDEDYVSP-LQ 235
FFTSFGARDR ++++FRLWQNALLEK L P+ELWH VHQCYG+ELGLTS+DEDYV P
Sbjct: 182 FFTSFGARDRTYMMMFRLWQNALLEKPLCPKELWHFVHQCYGNELGLTSDDEDYVPPDDD 241
Query: 236 LNGLGTPKEVG-DVIALSDITSSGAADRSQEPSPVGSRRGHVTPNL-SRASSDADHGAEE 293
N +G +E+ + ++D +S + + + SP ++ L S SS+A +
Sbjct: 242 FNTMGYCEEIPVEENEVNDSSSKSSIETKPDASPQLPKKSITNSTLTSTGSSEAPVSFDG 301
Query: 294 DKEEQVDSQPDASSSQTVTPVAEPPSTEPTQPDGPTTLGPLDLLPSEELLTDTSNSSSST 353
E+ + D S + + + E + P LD +E++ T+ S+ SS T
Sbjct: 302 LPLEEEALEGDGSLEKEL--AIDNIMGEKIEMIAPVNSPSLDFNDNEDIPTELSD-SSDT 358
Query: 354 GEEADLAALLPDLSGRLLINSVFHVGAERLQQMLFSDSPFLQGFLQQCKFTDVTLSPWSG 413
+E ++ A DLSGR +N VF+ ++L +LF++SPF + F++Q +F+D+ PW
Sbjct: 359 HDEGEVQAFYEDLSGRQYVNEVFNFSVDKLYDLLFTNSPFQRDFMEQRRFSDIIFHPWKK 418
Query: 414 DSKCHQRRVLTYTIPISNPLGPKSASVVETQTLFRRGPQAGGCVVDSEVLTQGIPYQDYF 473
+ +Q RV+ YTI ++NPL PK+A+V ETQT+++ ++ V+D+EVLT +PY DYF
Sbjct: 419 EENGNQSRVILYTITLTNPLAPKTATVRETQTMYKASQESECYVIDAEVLTHDVPYHDYF 478
Query: 474 YTAHRYCILGLARNKARLRVSSEIRYRKQPWSLVKSLIEKNSWSGIEDYFHHLERELAKA 533
YT +RY + +ARNK+RLRVS+E+RYRKQPW LVK+ IEKN WSG+EDYF HLE ELAK
Sbjct: 479 YTINRYTLTRVARNKSRLRVSTELRYRKQPWGLVKTFIEKNFWSGLEDYFRHLESELAKT 538
Query: 534 EKLSLEE----GGKDARGLLSGLRRRKRPLSWRAHGDGPQ---------HPDPDPCARAG 580
E L E K+ + +RRRKRP AH P P +
Sbjct: 539 ESTYLAEMHRQSPKEKASKTTTVRRRKRP---HAHLRVPHLEEVMSPVTTPTDEDVGHRI 595
Query: 581 IHTSGSLSSRFSEPSVDQG-PGAGIPSALVLISIVICVSLIILIALNVLLFYRLWSLERT 639
H +GS +R G + L++IS VIC SL++L+ LN++LFY+LW LE T
Sbjct: 596 KHVAGSTQTRHIPEDTPNGFHLQSVSKLLLVISCVICFSLVLLVILNMMLFYKLWMLEYT 655
Query: 640 AHTFESWHSLALAKGKFPQTATEWAEILALQKQFHSVEVHKWRQILRASVELLDEMKFSL 699
T +W L L + + PQ+ TEWA++L Q+++H E+ KWR+I+++SV LLD+MK SL
Sbjct: 656 TQTLTAWQGLRLQE-RLPQSQTEWAQLLESQQKYHDTELQKWREIIKSSVMLLDQMKDSL 714
Query: 700 EKLHQGITVSD 710
L GI D
Sbjct: 715 INLQNGIRSRD 725
>gi|187936935 GRAM domain containing 1C [Homo sapiens]
Length = 662
Score = 438 bits (1127), Expect = e-123
Identities = 262/632 (41%), Positives = 373/632 (59%), Gaps = 48/632 (7%)
Query: 78 WYSMLSPTYKQRNEDFRKLFSKLPEAERLIVDYSCALQREILLQGRLYLSENWICFYSNI 137
W S S TYK RNE++R+ F+ LP+ ERLI DY+CALQR+ILLQGRLYLSENW+CFYSNI
Sbjct: 58 WIS--SSTYKDRNEEYRRQFTHLPDTERLIADYACALQRDILLQGRLYLSENWLCFYSNI 115
Query: 138 FRWETTISIQLKEVTCLKKEKTAKLIPNAIQICTESEKHFFTSFGARDRCFLLIFRLWQN 197
FRWETTISI LK +T + KEKTA+LIPNAIQI TESEK FFTSFGARDR +L IFRLWQN
Sbjct: 116 FRWETTISIALKNITFMTKEKTARLIPNAIQIVTESEKFFFTSFGARDRSYLSIFRLWQN 175
Query: 198 ALLEKTLSPRELWHLVHQCYGSELGLTSEDEDYVSPLQLNGLGTPKEVGDVIALSDITSS 257
LL+K+L+ +E W L+ Q YG+ELGL +E+ + +S L + + P+ G S + S
Sbjct: 176 VLLDKSLTRQEFWQLLQQNYGTELGLNAEEMENLS-LSIEDV-QPRSPG----RSSLDDS 229
Query: 258 GAADRSQEPSPVGSRRGHVTPNLSRASSDADHGAEEDKE--EQVDSQPDASSSQTVTPVA 315
G D S + ++SR S K + +SQ + + +++ P
Sbjct: 230 GERDEKLSKS-----ISFTSESISRVSETESFDGNSSKGGLGKEESQNEKQTKKSLLPTL 284
Query: 316 EPPSTEPTQPDGPTTLGPLDLLPSEELLTDTSNSSSSTGEEADLAALLPDLSGRLLINSV 375
E T LDL +E L D S++S S EE DL GRL IN +
Sbjct: 285 EKKLTRVPSKS-------LDLNKNEYLSLDKSSTSDSVDEE---NVPEKDLHGRLFINRI 334
Query: 376 FHVGAERLQQMLFSDSPFLQGFLQQCKFTDVTLSPWSGDSKCHQRRVLTYTIPISNPLGP 435
FH+ A+R+ ++LF+ S F+Q F DV +PW+ + Q R +TYTI +++PL
Sbjct: 335 FHISADRMFELLFTSSRFMQKFASSRNIIDVVSTPWTAELGGDQLRTMTYTIVLNSPLTG 394
Query: 436 KSASVVETQTLFRRGPQAGGCVVDSEVLTQGIPYQDYFYTAHRYCILGLARNKARLRVSS 495
K + E QTL++ +A +VDSEVLT +PY DYFYT +RYCI+ ++ K RLRVS+
Sbjct: 395 KCTAATEKQTLYKESREARFYLVDSEVLTHDVPYHDYFYTVNRYCIIRSSKQKCRLRVST 454
Query: 496 EIRYRKQPWSLVKSLIEKNSWSGIEDYFHHLERELAKAEKL---SLEEGGKDARGLLSGL 552
+++YRKQPW LVKSLIEKNSWS +EDYF LE +L E + ++E+ GK L+GL
Sbjct: 455 DLKYRKQPWGLVKSLIEKNSWSSLEDYFKQLESDLLIEESVLNQAIEDPGK-----LTGL 509
Query: 553 RRRKRPLSWRAHGDGPQHPDPDPCARAGIHTSGSLSSRFSEPSVDQGPGAGIPSALVLIS 612
RRR+R + R P+ G+ G ++ + E + + V +
Sbjct: 510 RRRRRTFN-RTAETVPKLSSQHSSGDVGLGAKGDITGKKKE----------MENYNVTLI 558
Query: 613 IVICVSLIILIALNVLLFYRLWSLERTAHTFESWHSLALAKGKFPQTATEWAEILALQKQ 672
+V+ + +++L+ LNV LF +L +E H +S++ L L + K A++ A Q
Sbjct: 559 VVMSIFVLLLVLLNVTLFLKLSKIE---HAAQSFYRLRLQEEKSLNLASDMVS-RAETIQ 614
Query: 673 FHSVEVHKWRQILRASVELLDEMKFSLEKLHQ 704
+ + H+ + +LR S+ +L+++K SL L +
Sbjct: 615 KNKDQAHRLKGVLRDSIVMLEQLKSSLIMLQK 646
>gi|226443028 GRAM domain containing 3 isoform 5 [Homo sapiens]
Length = 416
Score = 106 bits (264), Expect = 9e-23
Identities = 60/164 (36%), Positives = 91/164 (55%), Gaps = 5/164 (3%)
Query: 28 PSRPPPEPEPGTMVEKGSDSSSEKGGVPGTPSTQSLGSRNFIRNSKKMQSWYSMLSPTYK 87
PS P+ ++ S SS + + + S+N + +K S S +
Sbjct: 36 PSVEADSPDQKKIISLWSKSSFDGASLASDKNDCKTESKNDPKTERKKSS-----SSSQY 90
Query: 88 QRNEDFRKLFSKLPEAERLIVDYSCALQREILLQGRLYLSENWICFYSNIFRWETTISIQ 147
+ N F KLF +P E L ++CALQ+EIL QG+L++SENWICF+S +F +T ISI
Sbjct: 91 KANMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISIP 150
Query: 148 LKEVTCLKKEKTAKLIPNAIQICTESEKHFFTSFGARDRCFLLI 191
VT +KK KTA L+PNA+ I T ++++ F S +RD + L+
Sbjct: 151 AFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYKLL 194
>gi|226443011 GRAM domain containing 3 isoform 1 [Homo sapiens]
Length = 447
Score = 106 bits (264), Expect = 9e-23
Identities = 60/164 (36%), Positives = 91/164 (55%), Gaps = 5/164 (3%)
Query: 28 PSRPPPEPEPGTMVEKGSDSSSEKGGVPGTPSTQSLGSRNFIRNSKKMQSWYSMLSPTYK 87
PS P+ ++ S SS + + + S+N + +K S S +
Sbjct: 67 PSVEADSPDQKKIISLWSKSSFDGASLASDKNDCKTESKNDPKTERKKSS-----SSSQY 121
Query: 88 QRNEDFRKLFSKLPEAERLIVDYSCALQREILLQGRLYLSENWICFYSNIFRWETTISIQ 147
+ N F KLF +P E L ++CALQ+EIL QG+L++SENWICF+S +F +T ISI
Sbjct: 122 KANMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISIP 181
Query: 148 LKEVTCLKKEKTAKLIPNAIQICTESEKHFFTSFGARDRCFLLI 191
VT +KK KTA L+PNA+ I T ++++ F S +RD + L+
Sbjct: 182 AFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYKLL 225
>gi|226443007 GRAM domain containing 3 isoform 2 [Homo sapiens]
Length = 432
Score = 106 bits (264), Expect = 9e-23
Identities = 60/164 (36%), Positives = 91/164 (55%), Gaps = 5/164 (3%)
Query: 28 PSRPPPEPEPGTMVEKGSDSSSEKGGVPGTPSTQSLGSRNFIRNSKKMQSWYSMLSPTYK 87
PS P+ ++ S SS + + + S+N + +K S S +
Sbjct: 52 PSVEADSPDQKKIISLWSKSSFDGASLASDKNDCKTESKNDPKTERKKSS-----SSSQY 106
Query: 88 QRNEDFRKLFSKLPEAERLIVDYSCALQREILLQGRLYLSENWICFYSNIFRWETTISIQ 147
+ N F KLF +P E L ++CALQ+EIL QG+L++SENWICF+S +F +T ISI
Sbjct: 107 KANMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISIP 166
Query: 148 LKEVTCLKKEKTAKLIPNAIQICTESEKHFFTSFGARDRCFLLI 191
VT +KK KTA L+PNA+ I T ++++ F S +RD + L+
Sbjct: 167 AFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYKLL 210
>gi|226443022 GRAM domain containing 3 isoform 4 [Homo sapiens]
Length = 440
Score = 104 bits (260), Expect = 3e-22
Identities = 66/186 (35%), Positives = 97/186 (52%), Gaps = 12/186 (6%)
Query: 6 PHSGRSTPSSSPSLRKRLQLLPPSRPPPEPEPGTMVEKGSDSSSEKGGVPGTPSTQSLGS 65
PH R TP + + P+ + + G+ +S+K T+S
Sbjct: 45 PHLWRRTPQTRRKSLAYAHIFSPNLCFIQDQESKSSFDGASLASDKNDC----KTES--- 97
Query: 66 RNFIRNSKKMQSWYSMLSPTYKQRNEDFRKLFSKLPEAERLIVDYSCALQREILLQGRLY 125
+N K + S S YK N F KLF +P E L ++CALQ+EIL QG+L+
Sbjct: 98 ----KNDPKTERKKSSSSSQYKA-NMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLF 152
Query: 126 LSENWICFYSNIFRWETTISIQLKEVTCLKKEKTAKLIPNAIQICTESEKHFFTSFGARD 185
+SENWICF+S +F +T ISI VT +KK KTA L+PNA+ I T ++++ F S +RD
Sbjct: 153 VSENWICFHSKVFGKDTKISIPAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRD 212
Query: 186 RCFLLI 191
+ L+
Sbjct: 213 STYKLL 218
>gi|226443017 GRAM domain containing 3 isoform 3 [Homo sapiens]
Length = 328
Score = 100 bits (250), Expect = 4e-21
Identities = 49/102 (48%), Positives = 69/102 (67%)
Query: 90 NEDFRKLFSKLPEAERLIVDYSCALQREILLQGRLYLSENWICFYSNIFRWETTISIQLK 149
N F KLF +P E L ++CALQ+EIL QG+L++SENWICF+S +F +T ISI
Sbjct: 5 NMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISIPAF 64
Query: 150 EVTCLKKEKTAKLIPNAIQICTESEKHFFTSFGARDRCFLLI 191
VT +KK KTA L+PNA+ I T ++++ F S +RD + L+
Sbjct: 65 SVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYKLL 106
>gi|60593095 GRAM domain containing 2 [Homo sapiens]
Length = 354
Score = 92.0 bits (227), Expect = 2e-18
Identities = 50/127 (39%), Positives = 79/127 (62%), Gaps = 3/127 (2%)
Query: 85 TYKQRNEDFRKLFSKLPEAERLIVDYSCALQREILLQGRLYLSENWICFYSNIFRWETTI 144
T + N+ + KLF +P E ++ SCALQR+ LLQGRLY+S NW+CF++++F + +
Sbjct: 66 TLNKYNQQYHKLFKDVPLEEVVLKVCSCALQRDFLLQGRLYISPNWLCFHASLFGKDIKV 125
Query: 145 SIQLKEVTCLKKEKTAKLIPNAIQICTE-SEKHFFTSFGARDRCFLLIFRLWQN--ALLE 201
I + V +KK K A+L+PN + I T S+K+ F S +RD + L+ R+ + +
Sbjct: 126 VIPVVSVQMIKKHKMARLLPNGLAITTNTSQKYIFVSLLSRDSVYDLLRRVCTHLQPSSK 185
Query: 202 KTLSPRE 208
K+LS RE
Sbjct: 186 KSLSVRE 192
>gi|139394668 TBC1 domain family, member 9 (with GRAM domain) [Homo
sapiens]
Length = 1266
Score = 64.7 bits (156), Expect = 3e-10
Identities = 39/110 (35%), Positives = 66/110 (60%), Gaps = 3/110 (2%)
Query: 86 YKQRNEDFRKLFSKLPEAERLIVDYSCALQR-EILLQGRLYLSENWICFYSNIFRWETTI 144
+K+ F +LF +PE E+L+ YSC+ + ++ QG +YLS N +CFYS + E +
Sbjct: 141 FKEAIVKFHRLFG-MPEEEKLVNYYSCSYWKGKVPRQGWMYLSINHLCFYSFLMGREAKL 199
Query: 145 SIQLKEVTCLKKEKTAKLIPNAIQICTESEKHFFTSFGARDRCFLLIFRL 194
I+ ++T L+K T L+P+ I++ T S +HFF+ F + F L+ +L
Sbjct: 200 VIRWVDITQLEKNATL-LLPDVIKVSTRSSEHFFSVFLNINETFKLMEQL 248
Score = 45.8 bits (107), Expect = 1e-04
Identities = 31/107 (28%), Positives = 61/107 (57%), Gaps = 6/107 (5%)
Query: 87 KQRNEDFRKLFSKLPEAERLIVDYSCALQ---REILLQGRLYLSENWICFYSNIFRWETT 143
+ ++E +R LF +LP+ E+L C L ++ + G++++S N+ICF S +
Sbjct: 289 RAKSERYRALF-RLPKDEKLDGHTDCTLWTPFNKMHILGQMFVSTNYICFTSKEENL-CS 346
Query: 144 ISIQLKEVTCLKKEKTAKLIPNAIQICTESEKHFFTSFGARDRCFLL 190
+ I L+EVT ++K ++ ++P+ + I T + F + +DR FL+
Sbjct: 347 LIIPLREVTIVEKADSSSVLPSPLSISTRNRMTFLFA-NLKDRDFLV 392
>gi|38570103 TBC1 domain family, member 8B (with GRAM domain)
isoform b [Homo sapiens]
Length = 632
Score = 62.0 bits (149), Expect = 2e-09
Identities = 40/109 (36%), Positives = 64/109 (58%), Gaps = 5/109 (4%)
Query: 93 FRKLFSKLPEAERLIVDYSCALQR-EILLQGRLYLSENWICFYSNIFRWETTISIQLKEV 151
F K F LPE E+L+ YSC+ + + QG LYLS N++ FYS + E + I EV
Sbjct: 147 FEKCFG-LPEKEKLVTYYSCSYWKGRVPCQGWLYLSTNFLSFYSFLLGSEIKLIISWDEV 205
Query: 152 TCLKKEKTAKLI-PNAIQICTESEKHFFTSFGARDRCFLLIFRLWQNAL 199
+ K EKT+ +I +I +C++ E H+F+ F ++ +LL+ +L A+
Sbjct: 206 S--KLEKTSNVILTESIHVCSQGENHYFSMFLHINQTYLLMEQLANYAI 252
Score = 30.8 bits (68), Expect = 4.6
Identities = 22/73 (30%), Positives = 36/73 (49%), Gaps = 5/73 (6%)
Query: 87 KQRNEDFRKLFSKLPEAERLIVDYSCALQ---REILLQGRLYLSENWICFYSNIFRWETT 143
+ +E F F +LP+ E L + C L G++ +SEN+ICF S + +
Sbjct: 281 RAHSEQFNAFF-RLPKGESLKEVHECFLWVPFSHFNTHGKMCISENYICFASQDGN-QCS 338
Query: 144 ISIQLKEVTCLKK 156
+ I L+EV + K
Sbjct: 339 VIIPLREVLAIDK 351
>gi|38570101 TBC1 domain family, member 8B (with GRAM domain)
isoform a [Homo sapiens]
Length = 1120
Score = 62.0 bits (149), Expect = 2e-09
Identities = 40/109 (36%), Positives = 64/109 (58%), Gaps = 5/109 (4%)
Query: 93 FRKLFSKLPEAERLIVDYSCALQR-EILLQGRLYLSENWICFYSNIFRWETTISIQLKEV 151
F K F LPE E+L+ YSC+ + + QG LYLS N++ FYS + E + I EV
Sbjct: 147 FEKCFG-LPEKEKLVTYYSCSYWKGRVPCQGWLYLSTNFLSFYSFLLGSEIKLIISWDEV 205
Query: 152 TCLKKEKTAKLI-PNAIQICTESEKHFFTSFGARDRCFLLIFRLWQNAL 199
+ K EKT+ +I +I +C++ E H+F+ F ++ +LL+ +L A+
Sbjct: 206 S--KLEKTSNVILTESIHVCSQGENHYFSMFLHINQTYLLMEQLANYAI 252
Score = 30.8 bits (68), Expect = 4.6
Identities = 22/73 (30%), Positives = 36/73 (49%), Gaps = 5/73 (6%)
Query: 87 KQRNEDFRKLFSKLPEAERLIVDYSCALQ---REILLQGRLYLSENWICFYSNIFRWETT 143
+ +E F F +LP+ E L + C L G++ +SEN+ICF S + +
Sbjct: 281 RAHSEQFNAFF-RLPKGESLKEVHECFLWVPFSHFNTHGKMCISENYICFASQDGN-QCS 338
Query: 144 ISIQLKEVTCLKK 156
+ I L+EV + K
Sbjct: 339 VIIPLREVLAIDK 351
>gi|45597177 TBC1 domain family, member 9B (with GRAM domain)
isoform b [Homo sapiens]
Length = 1233
Score = 58.9 bits (141), Expect = 2e-08
Identities = 34/97 (35%), Positives = 57/97 (58%), Gaps = 3/97 (3%)
Query: 86 YKQRNEDFRKLFSKLPEAERLIVDYSCALQR-EILLQGRLYLSENWICFYSNIFRWETTI 144
+K+ RK F +PE E+L+ YSC+ + + QG LYL+ N +CFYS + E ++
Sbjct: 137 FKEAELKMRKQFG-MPEGEKLVNYYSCSYWKGRVPRQGWLYLTVNHLCFYSFLLGKEVSL 195
Query: 145 SIQLKEVTCLKKEKTAKLIPNAIQICTESEKHFFTSF 181
+Q ++T L+K T L P +I++ T ++ FF+ F
Sbjct: 196 VVQWVDITRLEKNATL-LFPESIRVDTRDQELFFSMF 231
Score = 50.1 bits (118), Expect = 7e-06
Identities = 34/107 (31%), Positives = 61/107 (57%), Gaps = 6/107 (5%)
Query: 87 KQRNEDFRKLFSKLPEAERLIVDYSCALQ---REILLQGRLYLSENWICFYSNIFRWETT 143
+ +NE +R F +LP ERL SC L ++ + G++++S N+ICF S
Sbjct: 284 RAKNECYRATF-RLPRDERLDGHTSCTLWTPFNKLHIPGQMFISNNYICFASK-EEDACH 341
Query: 144 ISIQLKEVTCLKKEKTAKLIPNAIQICTESEKHFFTSFGARDRCFLL 190
+ I L+EVT ++K ++ ++P+ + I T+S+ F + +DR FL+
Sbjct: 342 LIIPLREVTIVEKADSSSVLPSPLSISTKSKMTFLFA-NLKDRDFLV 387
>gi|45597175 TBC1 domain family, member 9B (with GRAM domain)
isoform a [Homo sapiens]
Length = 1250
Score = 58.9 bits (141), Expect = 2e-08
Identities = 34/97 (35%), Positives = 57/97 (58%), Gaps = 3/97 (3%)
Query: 86 YKQRNEDFRKLFSKLPEAERLIVDYSCALQR-EILLQGRLYLSENWICFYSNIFRWETTI 144
+K+ RK F +PE E+L+ YSC+ + + QG LYL+ N +CFYS + E ++
Sbjct: 137 FKEAELKMRKQFG-MPEGEKLVNYYSCSYWKGRVPRQGWLYLTVNHLCFYSFLLGKEVSL 195
Query: 145 SIQLKEVTCLKKEKTAKLIPNAIQICTESEKHFFTSF 181
+Q ++T L+K T L P +I++ T ++ FF+ F
Sbjct: 196 VVQWVDITRLEKNATL-LFPESIRVDTRDQELFFSMF 231
Score = 50.1 bits (118), Expect = 7e-06
Identities = 34/107 (31%), Positives = 61/107 (57%), Gaps = 6/107 (5%)
Query: 87 KQRNEDFRKLFSKLPEAERLIVDYSCALQ---REILLQGRLYLSENWICFYSNIFRWETT 143
+ +NE +R F +LP ERL SC L ++ + G++++S N+ICF S
Sbjct: 284 RAKNECYRATF-RLPRDERLDGHTSCTLWTPFNKLHIPGQMFISNNYICFASK-EEDACH 341
Query: 144 ISIQLKEVTCLKKEKTAKLIPNAIQICTESEKHFFTSFGARDRCFLL 190
+ I L+EVT ++K ++ ++P+ + I T+S+ F + +DR FL+
Sbjct: 342 LIIPLREVTIVEKADSSSVLPSPLSISTKSKMTFLFA-NLKDRDFLV 387
>gi|156231067 TBC1 domain family, member 8 [Homo sapiens]
Length = 1140
Score = 48.1 bits (113), Expect = 3e-05
Identities = 35/116 (30%), Positives = 61/116 (52%), Gaps = 10/116 (8%)
Query: 87 KQRNEDFRKLFSKL------PEAERLIVDYSCALQR-EILLQGRLYLSENWICFYSNIFR 139
++ E FR+ K PEAE+L+ YSC + + QG LYLS N +CFYS
Sbjct: 134 EEEPEKFREALVKFEARFNFPEAEKLVTYYSCCCWKGRVPRQGWLYLSINHLCFYSFFLG 193
Query: 140 WETTISIQLKEVTCLKKEKTAKL-IPNAIQICTESEKHFFTSFGARDRCFLLIFRL 194
E + + ++ K E+T+ + + + I+I T++++ F+ F D F ++ +L
Sbjct: 194 KELKLVVPWVDIQ--KLERTSNVFLTDTIRITTQNKERDFSMFLNLDEVFKVMEQL 247
Score = 42.4 bits (98), Expect = 0.002
Identities = 49/187 (26%), Positives = 82/187 (43%), Gaps = 24/187 (12%)
Query: 87 KQRNEDFRKLFSKLPEAERLIVDYSCALQREIL---LQGRLYLSENWICFYSNIFRWETT 143
+ +NE FR F +LP E+L C+L GR++ S+++ICF S
Sbjct: 281 RAQNEFFRAFF-RLPRKEKLHAVVDCSLWTPFSRCHTTGRMFASDSYICFASREDGC-CK 338
Query: 144 ISIQLKEVTCLKKEKTAKLIPNAIQICTESEKHFFTSFGARDRCFLLIFRLWQNALLEKT 203
I + L+EV ++K + L+P+ I + S K F RDR ++L+E
Sbjct: 339 IILPLREVVSIEKMEDTSLLPHPIIVSIRS-KVAFQFIELRDR----------DSLVEAL 387
Query: 204 LSPRELWHLVHQCYGSELGLTSEDEDYVS-PLQLNGLGTPKEVGDVIALSDITSSGAADR 262
L+ + H H + TS D+D S + + GD L ++S + +
Sbjct: 388 LARLKQVHANHPVHYD----TSADDDMASLVFHSTSMCSDHRFGD---LEMMSSQNSEES 440
Query: 263 SQEPSPV 269
+E SP+
Sbjct: 441 EKEKSPL 447
>gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax
homolog 2 [Homo sapiens]
Length = 1210
Score = 39.3 bits (90), Expect = 0.013
Identities = 36/138 (26%), Positives = 55/138 (39%), Gaps = 21/138 (15%)
Query: 240 GTPKEVGDVIALSDITSSGAADRSQEP----SPVGSRRGHVTPNLSRASSDADHGAEEDK 295
GT + D + LSD S + ++P +P + + P S SS A+ + D
Sbjct: 418 GTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDS 477
Query: 296 EEQVDSQPDASSS--------QTVTPVAEPPSTEPTQPDGPTTL---------GPLDLLP 338
+ DS+ ++SSS +T P EPP+T Q D T GP P
Sbjct: 478 DSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEP 537
Query: 339 SEELLTDTSNSSSSTGEE 356
+S S+T +E
Sbjct: 538 PRRHPESKGSSDSATSQE 555
>gi|113204617 skeletal muscle ryanodine receptor isoform 2 [Homo
sapiens]
Length = 5033
Score = 38.5 bits (88), Expect = 0.022
Identities = 26/61 (42%), Positives = 32/61 (52%), Gaps = 8/61 (13%)
Query: 1 MFDTTPHSGRSTPSSSPSLRKRLQL------LPPSRPPPEPEPGTMVEKGSDSSSEKGGV 54
M DTTP + TP SP L+++L + LPP P PEPEP EK + EK V
Sbjct: 4452 MGDTTP-AEPPTPEGSPILKRKLGVDGVEEELPPE-PEPEPEPELEPEKADAENGEKEEV 4509
Query: 55 P 55
P
Sbjct: 4510 P 4510
>gi|113204615 skeletal muscle ryanodine receptor isoform 1 [Homo
sapiens]
Length = 5038
Score = 38.5 bits (88), Expect = 0.022
Identities = 26/61 (42%), Positives = 32/61 (52%), Gaps = 8/61 (13%)
Query: 1 MFDTTPHSGRSTPSSSPSLRKRLQL------LPPSRPPPEPEPGTMVEKGSDSSSEKGGV 54
M DTTP + TP SP L+++L + LPP P PEPEP EK + EK V
Sbjct: 4457 MGDTTP-AEPPTPEGSPILKRKLGVDGVEEELPPE-PEPEPEPELEPEKADAENGEKEEV 4514
Query: 55 P 55
P
Sbjct: 4515 P 4515
>gi|46560555 transmembrane protein 132E [Homo sapiens]
Length = 984
Score = 38.1 bits (87), Expect = 0.029
Identities = 28/105 (26%), Positives = 39/105 (37%), Gaps = 1/105 (0%)
Query: 265 EPSPVGSRRGHVTPNLSRASSDADHGAEEDKEEQVDSQPDASSSQTVTPVAEPPSTEPTQ 324
E SP P + ++ + QV + D SS + AE P++ PT
Sbjct: 859 ELSPPAGNPLETVPAFCHGDHHSSGSSQTSVQSQVHGRGDGSSGGSARDQAEDPASSPTS 918
Query: 325 PDGPTTLGPLDLLPSEELLTDT-SNSSSSTGEEADLAALLPDLSG 368
LPSEEL D+ EE DL PD++G
Sbjct: 919 KRKRVKFTTFTTLPSEELAYDSVPAGEEDEEEEEDLGWGCPDVAG 963
>gi|34304354 phosphatase and actin regulator 3 isoform 2 [Homo
sapiens]
Length = 518
Score = 37.4 bits (85), Expect = 0.049
Identities = 28/82 (34%), Positives = 40/82 (48%), Gaps = 9/82 (10%)
Query: 292 EEDKEEQV---DSQPDASSSQTVTPVAEPPSTEPTQPDGPTTLGPLDL-----LPSEELL 343
E+D E + D P + S+ TP +E ++E QP P G + L S L
Sbjct: 77 EQDAESKTCNPDGGPRSVQSEPPTPKSETLTSEDAQPGSPLATGTDQVSLDKPLSSAAHL 136
Query: 344 TDTSNS-SSSTGEEADLAALLP 364
D + S+S+GEEAD +LLP
Sbjct: 137 DDAAKMPSASSGEEADAGSLLP 158
>gi|18087853 phosphatase and actin regulator 3 isoform 1 [Homo
sapiens]
Length = 559
Score = 37.4 bits (85), Expect = 0.049
Identities = 28/82 (34%), Positives = 40/82 (48%), Gaps = 9/82 (10%)
Query: 292 EEDKEEQV---DSQPDASSSQTVTPVAEPPSTEPTQPDGPTTLGPLDL-----LPSEELL 343
E+D E + D P + S+ TP +E ++E QP P G + L S L
Sbjct: 118 EQDAESKTCNPDGGPRSVQSEPPTPKSETLTSEDAQPGSPLATGTDQVSLDKPLSSAAHL 177
Query: 344 TDTSNS-SSSTGEEADLAALLP 364
D + S+S+GEEAD +LLP
Sbjct: 178 DDAAKMPSASSGEEADAGSLLP 199
>gi|151101459 SAPS domain family, member 1 [Homo sapiens]
Length = 881
Score = 37.4 bits (85), Expect = 0.049
Identities = 40/146 (27%), Positives = 59/146 (40%), Gaps = 19/146 (13%)
Query: 211 HLVHQCYGSELGLTSEDEDYVSPLQLNGLGTPKEVGDVIALSDITSSGAADRSQEPSPVG 270
+L+ CY + +DE+ + G G SD GA SQ G
Sbjct: 607 NLLEICYKDRIQQFDDDEEEEDEEEAQGSGE----------SD-GEDGAWQGSQLAR--G 653
Query: 271 SRRGHVTPNLSRASSDADHGAEEDKEEQVDSQPDASSSQTVTPVAEPPSTEPTQPDGPTT 330
+R G S S+D++ EED+EE+ D + +++ PS P QP GP+
Sbjct: 654 ARLGQPPGVRSGGSTDSEDEEEEDEEEEEDEEGIGCAARGGATPLSYPSPGP-QPPGPSW 712
Query: 331 LGPLDLLPSEELLTDTSNSSSSTGEE 356
D +P TD S +GEE
Sbjct: 713 TATFDPVP-----TDAPTSPRVSGEE 733
>gi|154146199 sal-like 3 [Homo sapiens]
Length = 1300
Score = 37.0 bits (84), Expect = 0.064
Identities = 35/107 (32%), Positives = 43/107 (40%), Gaps = 13/107 (12%)
Query: 238 GLGTPKEVGDVIALSDITSSGAADRS-QEPSPVGSRRGHVTPNLSRASSDADHGAEE--- 293
GL P V +D S+ A RS Q PSP S ++P L+ S AE
Sbjct: 527 GLQLPPTVPGAHGYADSPSATPASRSPQRPSPASSECASLSPGLNHVESGVSATAESPQS 586
Query: 294 -------DKEEQVDSQPDASSSQTVTPVAEPPSTEPTQPDG-PTTLG 332
K E V S P ++ PV S PT DG PT+LG
Sbjct: 587 LLGGPPLTKAEPV-SLPCTNARAGDAPVGAQASAAPTSVDGAPTSLG 632
>gi|38201677 teashirt family zinc finger 1 [Homo sapiens]
Length = 1032
Score = 37.0 bits (84), Expect = 0.064
Identities = 29/91 (31%), Positives = 39/91 (42%), Gaps = 1/91 (1%)
Query: 276 VTPNLSRASSDADHGAEEDKEEQVDSQPDASSSQTVTPVAEPPSTEPTQPDGPTTLGPLD 335
V NL S + + K S DAS ++ P PP T P GPTT P
Sbjct: 74 VYANLFSESCWSSLALDLKKSGSTTSTNDASQKESSAPTPTPP-TCPVSTTGPTTSTPST 132
Query: 336 LLPSEELLTDTSNSSSSTGEEADLAALLPDL 366
S + T+++SSS+G + AAL L
Sbjct: 133 SCSSSTSHSSTTSTSSSSGYDWHQAALAKTL 163
>gi|163310725 ER degradation enhancer, mannosidase alpha-like 3
[Homo sapiens]
Length = 932
Score = 37.0 bits (84), Expect = 0.064
Identities = 25/99 (25%), Positives = 49/99 (49%), Gaps = 7/99 (7%)
Query: 218 GSELGLTSEDEDYVSP--LQLNGLGTPKEVGDVIALSDITSSGAADRSQEPSPVGSRRGH 275
G ++ +S++ D V + N L + E ++L+D+ ++ + S++ S H
Sbjct: 817 GEQISSSSQEVDLVDQESSEENSLNSHPES---LSLADMDNAASISPSEQTS--NPTENH 871
Query: 276 VTPNLSRASSDADHGAEEDKEEQVDSQPDASSSQTVTPV 314
T NL+ +D D+ +E E + DS P+ S + V P+
Sbjct: 872 ETTNLNGECTDLDNQLQEQSETEEDSNPNVSWGKKVQPI 910
>gi|223468617 family with sequence similarity 75, member C1 [Homo
sapiens]
Length = 1188
Score = 36.6 bits (83), Expect = 0.084
Identities = 75/275 (27%), Positives = 94/275 (34%), Gaps = 53/275 (19%)
Query: 208 ELWHLVHQCYGSELGLTSEDEDYVSPLQLNGLGTPKEVGDVIALSDITSSGAADRSQEP- 266
E W L+ Q S LG E D+ QL+G P EVG T GA+ S EP
Sbjct: 105 ETWDLLSQLQ-SLLGPHLEKGDFG---QLSGPDPPGEVGKR------TPDGASRSSHEPM 154
Query: 267 -------SPVGSRRGHVTPNLSRASSDADHGAEEDKEEQVDSQPDASSSQTVTPVAEPPS 319
SP+ S AS+ SQP S P EPP+
Sbjct: 155 EDAAPIVSPLASPDPRTKHPQDLASTPPPGPMTTSVSSLSASQPPEPSLLLERPSPEPPA 214
Query: 320 TEPTQPDGPTTLG-----PLDLLP----SEELLTDTSNSS---------SSTGEEADLAA 361
P P P L P P LLT + S S DLAA
Sbjct: 215 LFPHPPHTPDPLACSPPPPKGFTPPPLRDSTLLTPSHCDSVALPLDTVPQSLSPREDLAA 274
Query: 362 LLPDLSGRLLINSVFHVGAERLQQMLFSDSPFLQGFLQQ---CKFTDVTLSPWSGDSKCH 418
+P +SG L S V A Q +QQ + D T+SP
Sbjct: 275 SVPAISG--LGGSNSQVSALSWSQETTKTWCIFNSSVQQDHLSRQRDTTMSP-------- 324
Query: 419 QRRVLTYTIPISNPLGPKSASVVETQTLFRRGPQA 453
+L P+S+ LGP+S + + FR P A
Sbjct: 325 ---LLFQAQPLSH-LGPESQPFISSTPQFRPTPMA 355
>gi|56549117 dynamin 1 isoform 2 [Homo sapiens]
Length = 851
Score = 35.8 bits (81), Expect = 0.14
Identities = 20/53 (37%), Positives = 29/53 (54%), Gaps = 6/53 (11%)
Query: 8 SGRSTPSSSPSLRKRLQLLPPSRPPPE-PEPGTMVEKGSDSSSEKGGVPGTPS 59
+GR +P+SSP+ ++R +PP+RP P PG + S GG P PS
Sbjct: 770 AGRRSPTSSPTPQRRAPAVPPARPGSRGPAPGP-----PPAGSALGGAPPVPS 817
>gi|59853099 dynamin 1 isoform 1 [Homo sapiens]
Length = 864
Score = 35.8 bits (81), Expect = 0.14
Identities = 20/53 (37%), Positives = 29/53 (54%), Gaps = 6/53 (11%)
Query: 8 SGRSTPSSSPSLRKRLQLLPPSRPPPE-PEPGTMVEKGSDSSSEKGGVPGTPS 59
+GR +P+SSP+ ++R +PP+RP P PG + S GG P PS
Sbjct: 770 AGRRSPTSSPTPQRRAPAVPPARPGSRGPAPGP-----PPAGSALGGAPPVPS 817
>gi|29789008 Huntingtin interacting protein C isoform 2 [Homo
sapiens]
Length = 858
Score = 35.8 bits (81), Expect = 0.14
Identities = 27/77 (35%), Positives = 37/77 (48%), Gaps = 11/77 (14%)
Query: 7 HSGRSTPSSSPSLRKRLQLLPPSRPPPEPEPGTMVEKGSDSSS-----EKGGVP----GT 57
H +PS S S + L PPS PP+ E GS+ SS E GG G+
Sbjct: 694 HKRSHSPSGSESEEEELP--PPSLRPPKRRRRNPSESGSEPSSSLDSVESGGAALGGRGS 751
Query: 58 PSTQSLGSRNFIRNSKK 74
PS+ LG+ + +R +KK
Sbjct: 752 PSSHLLGADHGLRKAKK 768
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.132 0.397
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,969,582
Number of Sequences: 37866
Number of extensions: 1659599
Number of successful extensions: 12784
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 59
Number of HSP's successfully gapped in prelim test: 189
Number of HSP's that attempted gapping in prelim test: 11840
Number of HSP's gapped (non-prelim): 1069
length of query: 724
length of database: 18,247,518
effective HSP length: 110
effective length of query: 614
effective length of database: 14,082,258
effective search space: 8646506412
effective search space used: 8646506412
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.