Search of human proteins with 91208423

Search of human proteins with 91208423

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|91208423 thyroid receptor-interacting protein 6 [Homo
sapiens]
         (476 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|91208423 thyroid receptor-interacting protein 6 [Homo sapiens]    1030   0.0  
gi|5031887 LIM domain containing preferred translocation partner...   407   e-113
gi|58530845 zyxin [Homo sapiens]                                      293   3e-79
gi|4508047 zyxin [Homo sapiens]                                       293   3e-79
gi|14249622 ajuba isoform 1 [Homo sapiens]                            224   1e-58
gi|7657307 LIM domains containing 1 [Homo sapiens]                    223   3e-58
gi|122937269 Wilms tumor 1 interacting protein [Homo sapiens]         223   4e-58
gi|66932982 filamin-binding LIM protein-1 isoform a [Homo sapiens]    197   2e-50
gi|66932988 filamin-binding LIM protein-1 isoform c [Homo sapiens]    192   7e-49
gi|37675280 ajuba isoform 2 [Homo sapiens]                            150   2e-36
gi|66932986 filamin-binding LIM protein-1 isoform b [Homo sapiens]    125   6e-29
gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens]            101   1e-21
gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]             101   1e-21
gi|170932516 paxillin isoform 2 [Homo sapiens]                        100   3e-21
gi|170932514 paxillin isoform 1 [Homo sapiens]                        100   4e-21
gi|170932518 paxillin isoform 3 [Homo sapiens]                         97   3e-20
gi|109638745 transforming growth factor beta 1 induced transcrip...    95   1e-19
gi|21361591 transforming growth factor beta 1 induced transcript...    95   1e-19
gi|194272207 actin binding LIM protein family, member 2 isoform ...    90   5e-18
gi|153792514 actin binding LIM protein family, member 2 isoform ...    90   5e-18
gi|194272204 actin binding LIM protein family, member 2 isoform ...    90   5e-18
gi|194272202 actin binding LIM protein family, member 2 isoform ...    90   5e-18
gi|194272200 actin binding LIM protein family, member 2 isoform ...    90   5e-18
gi|194272198 actin binding LIM protein family, member 2 isoform ...    90   5e-18
gi|194272196 actin binding LIM protein family, member 2 isoform ...    90   5e-18
gi|51173715 actin-binding LIM protein 1 isoform c [Homo sapiens]       89   9e-18
gi|51173713 actin-binding LIM protein 1 isoform b [Homo sapiens]       89   9e-18
gi|51173711 actin-binding LIM protein 1 isoform a [Homo sapiens]       88   1e-17
gi|54112385 four and a half LIM domains 3 [Homo sapiens]               87   3e-17
gi|221316659 leupaxin isoform 1 [Homo sapiens]                         82   1e-15

>gi|91208423 thyroid receptor-interacting protein 6 [Homo sapiens]
          Length = 476

 Score = 1030 bits (2662), Expect = 0.0
 Identities = 476/476 (100%), Positives = 476/476 (100%)

Query: 1   MSGPTWLPPKQPEPARAPQGRAIPRGTPGPPPAHGAALQPHPRVNFCPLPSEQCYQAPGG 60
           MSGPTWLPPKQPEPARAPQGRAIPRGTPGPPPAHGAALQPHPRVNFCPLPSEQCYQAPGG
Sbjct: 1   MSGPTWLPPKQPEPARAPQGRAIPRGTPGPPPAHGAALQPHPRVNFCPLPSEQCYQAPGG 60

Query: 61  PEDRGPAWVGSHGVLQHTQGLPADRGGLRPGSLDAEIDLLSSTLAELNGGRGHASRRPDR 120
           PEDRGPAWVGSHGVLQHTQGLPADRGGLRPGSLDAEIDLLSSTLAELNGGRGHASRRPDR
Sbjct: 61  PEDRGPAWVGSHGVLQHTQGLPADRGGLRPGSLDAEIDLLSSTLAELNGGRGHASRRPDR 120

Query: 121 QAYEPPPPPAYRTGSLKPNPASPLPASPYGGPTPASYTTASTPAGPAFPVQVKVAQPVRG 180
           QAYEPPPPPAYRTGSLKPNPASPLPASPYGGPTPASYTTASTPAGPAFPVQVKVAQPVRG
Sbjct: 121 QAYEPPPPPAYRTGSLKPNPASPLPASPYGGPTPASYTTASTPAGPAFPVQVKVAQPVRG 180

Query: 181 CGPPRRGASQASGPLPGPHFPLPGRGEVWGPGYRSQREPGPGAKEEAAGVSGPAGRGRGG 240
           CGPPRRGASQASGPLPGPHFPLPGRGEVWGPGYRSQREPGPGAKEEAAGVSGPAGRGRGG
Sbjct: 181 CGPPRRGASQASGPLPGPHFPLPGRGEVWGPGYRSQREPGPGAKEEAAGVSGPAGRGRGG 240

Query: 241 EHGPQVPLSQPPEDELDRLTKKLVHDMNHPPSGEYFGQCGGCGEDVVGDGAGVVALDRVF 300
           EHGPQVPLSQPPEDELDRLTKKLVHDMNHPPSGEYFGQCGGCGEDVVGDGAGVVALDRVF
Sbjct: 241 EHGPQVPLSQPPEDELDRLTKKLVHDMNHPPSGEYFGQCGGCGEDVVGDGAGVVALDRVF 300

Query: 301 HVGCFVCSTCRAQLRGQHFYAVERRAYCEGCYVATLEKCATCSQPILDRILRAMGKAYHP 360
           HVGCFVCSTCRAQLRGQHFYAVERRAYCEGCYVATLEKCATCSQPILDRILRAMGKAYHP
Sbjct: 301 HVGCFVCSTCRAQLRGQHFYAVERRAYCEGCYVATLEKCATCSQPILDRILRAMGKAYHP 360

Query: 361 GCFTCVVCHRGLDGIPFTVDATSQIHCIEDFHRKFAPRCSVCGGAIMPEPGQEETVRIVA 420
           GCFTCVVCHRGLDGIPFTVDATSQIHCIEDFHRKFAPRCSVCGGAIMPEPGQEETVRIVA
Sbjct: 361 GCFTCVVCHRGLDGIPFTVDATSQIHCIEDFHRKFAPRCSVCGGAIMPEPGQEETVRIVA 420

Query: 421 LDRSFHIGCYKCEECGLLLSSEGECQGCYPLDGHILCKACSAWRIQELSATVTTDC 476
           LDRSFHIGCYKCEECGLLLSSEGECQGCYPLDGHILCKACSAWRIQELSATVTTDC
Sbjct: 421 LDRSFHIGCYKCEECGLLLSSEGECQGCYPLDGHILCKACSAWRIQELSATVTTDC 476


>gi|5031887 LIM domain containing preferred translocation partner in
           lipoma [Homo sapiens]
          Length = 612

 Score =  407 bits (1046), Expect = e-113
 Identities = 257/600 (42%), Positives = 309/600 (51%), Gaps = 147/600 (24%)

Query: 1   MSGPTWLPPKQPEPARAPQGRAIPRGTPG---------PPPAHGAALQPHPRVNFCPLP- 50
           +S  T  PPK+  P  AP+ +  P   PG         PPP   ++  P    NF P P 
Sbjct: 34  ISVSTQQPPKKFAPVVAPKPKYNPYKQPGGEGDFLPPPPPPLDDSSALPSISGNFPPPPP 93

Query: 51  -SEQCYQAPGGPEDRGPAWVGSHGVLQHTQGLPADRGGLRPGSLDAEIDLLSSTLAELNG 109
             E+ ++  G P  +          L+            R  SLDAEID L+S LA+L  
Sbjct: 94  LDEEAFKVQGNPGGK---------TLEE-----------RRSSLDAEIDSLTSILADLEC 133

Query: 110 GRGHASRRPDRQAYEPPPPP--------------------AYRTGSLKPNPA---SPLPA 146
              +  R P         PP                    A +  +LKP PA    P+P 
Sbjct: 134 SSPYKPRPPQSSTGSTASPPVSTPVTGHKRMVIPNQPPLTATKKSTLKPQPAPQAGPIPV 193

Query: 147 SPYGG------PTPASYTTASTPAGPAFPVQVKVAQP----------------------- 177
           +P G       P PASYTTAST + P F VQVK AQP                       
Sbjct: 194 APIGTLKPQPQPVPASYTTASTSSRPTFNVQVKSAQPSPHYMAAPSSGQIYGSGPQGYNT 253

Query: 178 ----VRG-CGPP--RRGASQASGPLPGPHFPLPGRGEV------------WGPGY--RSQ 216
               V G C PP  R G   A  P PG   P PG G               GPGY  R+ 
Sbjct: 254 QPVPVSGQCPPPSTRGGMDYAYIPPPGLQ-PEPGYGYAPNQGRYYEGYYAAGPGYGGRND 312

Query: 217 REPG-------------PGAKEEAAGVSGPAGR--------------------------- 236
            +P              PG     AG   P G                            
Sbjct: 313 SDPTYGQQGHPNTWKREPGYTPPGAGNQNPPGMYPVTGPKKTYITDPVSAPCAPPLQPKG 372

Query: 237 GRGGEHGPQ-VPLSQPPEDELDRLTKKLVHDMNHPPSGEYFGQCGGCGEDVVGDGAGVVA 295
           G  G+ GP  V  S  PEDEL+ LTKK+++DM +PP+ EYFG+C  CGE+VVG+G G  A
Sbjct: 373 GHSGQLGPSSVAPSFRPEDELEHLTKKMLYDMENPPADEYFGRCARCGENVVGEGTGCTA 432

Query: 296 LDRVFHVGCFVCSTCRAQLRGQHFYAVERRAYCEGCYVATLEKCATCSQPILDRILRAMG 355
           +D+VFHV CF C  C  +LRGQ FYAVE++AYCE CY+ TLE+C  CS+PI++RILRA G
Sbjct: 433 MDQVFHVDCFTCIICNNKLRGQPFYAVEKKAYCEPCYINTLEQCNVCSKPIMERILRATG 492

Query: 356 KAYHPGCFTCVVCHRGLDGIPFTVDATSQIHCIEDFHRKFAPRCSVCGGAIMPEPGQEET 415
           KAYHP CFTCV+CHR LDGIPFTVDA   IHCIEDFH+KFAPRCSVC   IMP PGQEET
Sbjct: 493 KAYHPHCFTCVMCHRSLDGIPFTVDAGGLIHCIEDFHKKFAPRCSVCKEPIMPAPGQEET 552

Query: 416 VRIVALDRSFHIGCYKCEECGLLLSSEGECQGCYPLDGHILCKACSAWRIQELSATVTTD 475
           VRIVALDR FH+ CY+CE+CG LL SEG+ QGCYPLDGHILCK C++ RI+ L+A  +TD
Sbjct: 553 VRIVALDRDFHVHCYRCEDCGGLL-SEGDNQGCYPLDGHILCKTCNSARIRVLTAKASTD 611


>gi|58530845 zyxin [Homo sapiens]
          Length = 572

 Score =  293 bits (749), Expect = 3e-79
 Identities = 199/541 (36%), Positives = 257/541 (47%), Gaps = 97/541 (17%)

Query: 8   PPKQPEPARAPQGRA------IPRGTPGPPP-----------AHGAALQPHP---RVNFC 47
           PP  P   RA  GR        P   P PPP           A G A  P P     +F 
Sbjct: 46  PPPAPGAQRAQMGRVGEIPPPPPEDFPLPPPPLAGDGDDAEGALGGAFPPPPPPIEESFP 105

Query: 48  PLP-SEQCYQAPGGP--EDRGPAWVGSHGVLQHTQGLPADRGGLRPGSLDAEIDLLSSTL 104
           P P  E+ + +P  P  E+ GP               P  +   +  S+D EID LSS L
Sbjct: 106 PAPLEEEIFPSPPPPPEEEGGP----------EAPIPPPPQPREKVSSIDLEIDSLSSLL 155

Query: 105 AELNGGRGHASRRPDRQAYEPPP------------PPAYRTGSLKP--NPAS--PLPASP 148
            ++       +R      Y PPP            P A  T  L P  +P+S  PLP  P
Sbjct: 156 DDMTKNDPFKARVSS--GYVPPPVATPFSSKSSTKPAAGGTAPLPPWKSPSSSQPLPQVP 213

Query: 149 YGGPTPASYTTASTPAGPAFPVQVKV---AQPVRGCGPPRRGASQASGPLPGPHF----- 200
               +   +     P  P   VQ+ V    QPV       RG   AS P P P F     
Sbjct: 214 APAQSQTQFHVQPQPQ-PKPQVQLHVQSQTQPVSLANTQPRGPP-ASSPAPAPKFSPVTP 271

Query: 201 ---PLPGRGEVWGPG-----------------------------YRSQREPGPGAKEEAA 228
              P+  +     PG                             Y  QRE  P  +E+  
Sbjct: 272 KFTPVASKFSPGAPGGSGSQPNQKLGHPEALSAGTGSPQPPSFTYAQQREK-PRVQEKQH 330

Query: 229 GVSGPA-GRGRGGEHGPQVPLSQPPEDELDRLTKKLVHDMNHPPSGEYFGQ--CGGCGED 285
            V  PA  + +    G   PL+    +EL++LT++L+ DM HP          CG C + 
Sbjct: 331 PVPPPAQNQNQVRSPGAPGPLTLKEVEELEQLTQQLMQDMEHPQRQNVAVNELCGRCHQP 390

Query: 286 VVGDGAGVVALDRVFHVGCFVCSTCRAQLRGQHFYAVERRAYCEGCYVATLEKCATCSQP 345
           +      V AL ++FH+ CF C  C  QL+GQ FY++E   YCEGCY  TLEKC TC +P
Sbjct: 391 LARAQPAVRALGQLFHIACFTCHQCAQQLQGQQFYSLEGAPYCEGCYTDTLEKCNTCGEP 450

Query: 346 ILDRILRAMGKAYHPGCFTCVVCHRGLDGIPFTVDATSQIHCIEDFHRKFAPRCSVCGGA 405
           I DR+LRA GKAYHP CFTCVVC R L+G  F VD  ++ HC+ D+H+++APRCSVC   
Sbjct: 451 ITDRMLRATGKAYHPHCFTCVVCARPLEGTSFIVDQANRPHCVPDYHKQYAPRCSVCSEP 510

Query: 406 IMPEPGQEETVRIVALDRSFHIGCYKCEECGLLLSSEGECQGCYPLDGHILCKACSAWRI 465
           IMPEPG++ETVR+VALD++FH+ CYKCE+CG  LS E +  GC+PLDGH+LC+ C   R 
Sbjct: 511 IMPEPGRDETVRVVALDKNFHMKCYKCEDCGKPLSIEADDNGCFPLDGHVLCRKCHTARA 570

Query: 466 Q 466
           Q
Sbjct: 571 Q 571


>gi|4508047 zyxin [Homo sapiens]
          Length = 572

 Score =  293 bits (749), Expect = 3e-79
 Identities = 199/541 (36%), Positives = 257/541 (47%), Gaps = 97/541 (17%)

Query: 8   PPKQPEPARAPQGRA------IPRGTPGPPP-----------AHGAALQPHP---RVNFC 47
           PP  P   RA  GR        P   P PPP           A G A  P P     +F 
Sbjct: 46  PPPAPGAQRAQMGRVGEIPPPPPEDFPLPPPPLAGDGDDAEGALGGAFPPPPPPIEESFP 105

Query: 48  PLP-SEQCYQAPGGP--EDRGPAWVGSHGVLQHTQGLPADRGGLRPGSLDAEIDLLSSTL 104
           P P  E+ + +P  P  E+ GP               P  +   +  S+D EID LSS L
Sbjct: 106 PAPLEEEIFPSPPPPPEEEGGP----------EAPIPPPPQPREKVSSIDLEIDSLSSLL 155

Query: 105 AELNGGRGHASRRPDRQAYEPPP------------PPAYRTGSLKP--NPAS--PLPASP 148
            ++       +R      Y PPP            P A  T  L P  +P+S  PLP  P
Sbjct: 156 DDMTKNDPFKARVSS--GYVPPPVATPFSSKSSTKPAAGGTAPLPPWKSPSSSQPLPQVP 213

Query: 149 YGGPTPASYTTASTPAGPAFPVQVKV---AQPVRGCGPPRRGASQASGPLPGPHF----- 200
               +   +     P  P   VQ+ V    QPV       RG   AS P P P F     
Sbjct: 214 APAQSQTQFHVQPQPQ-PKPQVQLHVQSQTQPVSLANTQPRGPP-ASSPAPAPKFSPVTP 271

Query: 201 ---PLPGRGEVWGPG-----------------------------YRSQREPGPGAKEEAA 228
              P+  +     PG                             Y  QRE  P  +E+  
Sbjct: 272 KFTPVASKFSPGAPGGSGSQPNQKLGHPEALSAGTGSPQPPSFTYAQQREK-PRVQEKQH 330

Query: 229 GVSGPA-GRGRGGEHGPQVPLSQPPEDELDRLTKKLVHDMNHPPSGEYFGQ--CGGCGED 285
            V  PA  + +    G   PL+    +EL++LT++L+ DM HP          CG C + 
Sbjct: 331 PVPPPAQNQNQVRSPGAPGPLTLKEVEELEQLTQQLMQDMEHPQRQNVAVNELCGRCHQP 390

Query: 286 VVGDGAGVVALDRVFHVGCFVCSTCRAQLRGQHFYAVERRAYCEGCYVATLEKCATCSQP 345
           +      V AL ++FH+ CF C  C  QL+GQ FY++E   YCEGCY  TLEKC TC +P
Sbjct: 391 LARAQPAVRALGQLFHIACFTCHQCAQQLQGQQFYSLEGAPYCEGCYTDTLEKCNTCGEP 450

Query: 346 ILDRILRAMGKAYHPGCFTCVVCHRGLDGIPFTVDATSQIHCIEDFHRKFAPRCSVCGGA 405
           I DR+LRA GKAYHP CFTCVVC R L+G  F VD  ++ HC+ D+H+++APRCSVC   
Sbjct: 451 ITDRMLRATGKAYHPHCFTCVVCARPLEGTSFIVDQANRPHCVPDYHKQYAPRCSVCSEP 510

Query: 406 IMPEPGQEETVRIVALDRSFHIGCYKCEECGLLLSSEGECQGCYPLDGHILCKACSAWRI 465
           IMPEPG++ETVR+VALD++FH+ CYKCE+CG  LS E +  GC+PLDGH+LC+ C   R 
Sbjct: 511 IMPEPGRDETVRVVALDKNFHMKCYKCEDCGKPLSIEADDNGCFPLDGHVLCRKCHTARA 570

Query: 466 Q 466
           Q
Sbjct: 571 Q 571


>gi|14249622 ajuba isoform 1 [Homo sapiens]
          Length = 538

 Score =  224 bits (571), Expect = 1e-58
 Identities = 136/365 (37%), Positives = 189/365 (51%), Gaps = 52/365 (14%)

Query: 142 SPLPASP--YGGP---TPASYTTASTPAGPAFP-----VQVKVAQPVRGCG--------P 183
           SPLPA P  +G P    PA Y+    P+  A+P     +    AQ   G G        P
Sbjct: 175 SPLPAGPCLFGPPLAGAPAGYSPGGVPS--AYPELHAALDRLYAQRPAGFGCQESRHSYP 232

Query: 184 PRRGASQA-SGPLPGPHFPL------PGRGEVWGPGYRSQREPGPGAKEE---------A 227
           P  G+  A +G   G   PL      PGR  V G G     +   GA+ +          
Sbjct: 233 PALGSPGALAGAGVGAAGPLERRGAQPGRHSVTGYG-----DCAVGARYQDELTALLRLT 287

Query: 228 AGVSGPAGRGRGGEHGPQVP-LSQPPEDELDRLTKKLVHDMNHPPSGE-YFGQCGGCGED 285
            G  G     RG   G +   L +PP   +    +     M  P + E YFG C  C + 
Sbjct: 288 VGTGGREAGARGEPSGIEPSGLEEPPGPFVPEAARAR---MREPEAREDYFGTCIKCNKG 344

Query: 286 VVGDGAGVVALDRVFHVGCFVCSTCRAQLRGQHFYAVERRAYCEGCYVAT-----LEKCA 340
           + G      ALD ++H  CFVC +C   LR + FY+V    YCE  Y+ +      EKC 
Sbjct: 345 IYGQSNACQALDSLYHTQCFVCCSCGRTLRCKAFYSVNGSVYCEEDYLFSGFQEAAEKCC 404

Query: 341 TCSQPILDRILRAMGKAYHPGCFTCVVCHRGLDGIPFTVDATSQIHCIEDFHRKFAPRCS 400
            C   IL++IL+AMGK+YHPGCF C+VC++ LDGIPFTVD ++Q++C+ D+H+ +AP+C+
Sbjct: 405 VCGHLILEKILQAMGKSYHPGCFRCIVCNKCLDGIPFTVDFSNQVYCVTDYHKNYAPKCA 464

Query: 401 VCGGAIMPEPGQEETVRIVALDRSFHIGCYKCEECGLLLSSEGECQGCYPLDGHILCKAC 460
            CG  I+P  G E+ VR++++DR +H  CY CE+C + LS E  C  C+PLDGH+LC  C
Sbjct: 465 ACGQPILPSEGCEDIVRVISMDRDYHFECYHCEDCRMQLSDEEGC-CCFPLDGHLLCHGC 523

Query: 461 SAWRI 465
              R+
Sbjct: 524 HMQRL 528


>gi|7657307 LIM domains containing 1 [Homo sapiens]
          Length = 676

 Score =  223 bits (568), Expect = 3e-58
 Identities = 119/357 (33%), Positives = 182/357 (50%), Gaps = 46/357 (12%)

Query: 137 KPNPASPLPASPYGGPTPASYTTASTPAGPAFPVQVKVAQPVRGCGPPRRGASQASGPLP 196
           KPN    +   P+    P SY ++S P+     +       V G GP        +GP  
Sbjct: 328 KPN----VDPQPWFQDGPKSYLSSSAPSSSPAGLDGSQQGAVPGLGPKPGCTDLGTGPKL 383

Query: 197 GPHFPLPGRGEVWGPGYRSQREPGPGAKEEAAGVSGPAGRGRGGEHG---------PQVP 247
            P                S   P      E +   GP G    G  G         P+V 
Sbjct: 384 SP---------------TSLVHPVMSTLPELSCKEGPLGWSSDGSLGSVLLDSPSSPRVR 428

Query: 248 LSQPP------------EDELDRLTKKLVHDMNHPPSGEYFGQCGGCGEDVVGDGAGVVA 295
           L   P            E +L+ LT++L  +M+  P  +YFG C  C + V G G    A
Sbjct: 429 LPCQPLVPGPELRPSAAELKLEALTQRLEREMDAHPKADYFGACVKCSKGVFGAGQACQA 488

Query: 296 LDRVFHVGCFVCSTCRAQLRGQHFYAVERRAYCEGCYV-----ATLEKCATCSQPILDRI 350
           +  ++H  CF C+ C  +LRG+ FY V  + +CE  ++      + ++C  C   I+D I
Sbjct: 489 MGNLYHDTCFTCAACSRKLRGKAFYFVNGKVFCEEDFLYSGFQQSADRCFLCGHLIMDMI 548

Query: 351 LRAMGKAYHPGCFTCVVCHRGLDGIPFTVDATSQIHCIEDFHRKFAPRCSVCGGAIMPEP 410
           L+A+GK+YHPGCF CV+C+  LDG+PFTVD+ ++I+C+ D+H+  AP+C+ CG  I+P  
Sbjct: 549 LQALGKSYHPGCFRCVICNECLDGVPFTVDSENKIYCVRDYHKVLAPKCAACGLPILPPE 608

Query: 411 GQEETVRIVALDRSFHIGCYKCEECGLLLSSEGECQGCYPLDGHILCKACSAWRIQE 467
           G +ET+R+V++DR +H+ CY CE+CGL L+ E +   CYPL+ H+ C +C   R+++
Sbjct: 609 GSDETIRVVSMDRDYHVECYHCEDCGLELNDE-DGHRCYPLEDHLFCHSCHVKRLEK 664


>gi|122937269 Wilms tumor 1 interacting protein [Homo sapiens]
          Length = 430

 Score =  223 bits (567), Expect = 4e-58
 Identities = 142/407 (34%), Positives = 194/407 (47%), Gaps = 49/407 (12%)

Query: 85  RGGLRPGSLDAEIDLLSSTLAELNGGRGHASRRPDRQAYEPPPPPAYRTGSLKPNPAS-- 142
           R G RPG  D     L        G RG  S  P+  A           G   P  A+  
Sbjct: 34  RRGPRPGPGDEAAPAL--------GRRGKGSGGPEAGA------DGLSRGERGPRRAAVP 79

Query: 143 PLPASPYGGPTPA-SYTTASTPAGPAFPVQVKVAQPVRGCGPPRRGASQASGPLPGPHFP 201
            L A P G P  + + +      G A    + +    R  G PR G S    P PGP  P
Sbjct: 80  ELSAQPAGSPRASLAGSDGGGGGGSARSSGISLGYDQRH-GSPRSGRSD---PRPGPGPP 135

Query: 202 LPGRGEVWGPGYRSQREPG-------PGAKEEAAGVSGPAGRGR----------GGEHGP 244
             G          S+   G       PGA    A    PAG             G E GP
Sbjct: 136 SVGSARSSVSSLGSRGSAGAYADFLPPGACPAPARSPEPAGPAPFPLPALPLPPGREGGP 195

Query: 245 QVPLSQPPEDELDRLTKKLVHDMNHPPSGEYFGQCGGCGEDVVGDGAGVVALDRVFHVGC 304
                   E  L+ LT++L   +    + +YFG C  CG  + G      A+  ++H  C
Sbjct: 196 SAA-----ERRLEALTRELERALEARTARDYFGICIKCGLGIYGAQQACQAMGSLYHTDC 250

Query: 305 FVCSTCRAQLRGQHFYAVERRAYCEGCYV-----ATLEKCATCSQPILDRILRAMGKAYH 359
           F C +C  +LRG+ FY V  + YC+  ++      T +KC+ C   I++ IL+A+GK+YH
Sbjct: 251 FTCDSCGRRLRGKAFYNVGEKVYCQEDFLYSGFQQTADKCSVCGHLIMEMILQALGKSYH 310

Query: 360 PGCFTCVVCHRGLDGIPFTVDATSQIHCIEDFHRKFAPRCSVCGGAIMPEPGQEETVRIV 419
           PGCF C VC+  LDG+PFTVD  + I+C+ D+H  FAP+C+ C   I+P  G E T+R+V
Sbjct: 311 PGCFRCSVCNECLDGVPFTVDVENNIYCVRDYHTVFAPKCASCARPILPAQGCETTIRVV 370

Query: 420 ALDRSFHIGCYKCEECGLLLSSEGECQGCYPLDGHILCKACSAWRIQ 466
           ++DR +H+ CY CE+CGL LS E E + CYPL GH+LC+ C   R+Q
Sbjct: 371 SMDRDYHVACYHCEDCGLQLSGE-EGRRCYPLAGHLLCRRCHLRRLQ 416



 Score = 31.2 bits (69), Expect = 2.2
 Identities = 26/81 (32%), Positives = 31/81 (38%), Gaps = 4/81 (4%)

Query: 203 PGRGEVWGPGYRSQREPGPGAKEEAAGVSGPAGRGRGGEHGPQVPLSQPPEDELDRLTKK 262
           PG G    PG R +R P PG  +EAA   G  G+G GG       LS+           +
Sbjct: 25  PGCGS---PG-RGRRGPRPGPGDEAAPALGRRGKGSGGPEAGADGLSRGERGPRRAAVPE 80

Query: 263 LVHDMNHPPSGEYFGQCGGCG 283
           L       P     G  GG G
Sbjct: 81  LSAQPAGSPRASLAGSDGGGG 101


>gi|66932982 filamin-binding LIM protein-1 isoform a [Homo sapiens]
          Length = 373

 Score =  197 bits (500), Expect = 2e-50
 Identities = 120/339 (35%), Positives = 163/339 (48%), Gaps = 29/339 (8%)

Query: 138 PNPASPLPASPYGGPTPASYTTASTPAGPAFPVQVKVAQPVRGCGPPRR---------GA 188
           P P     A   G P+P +    +    PA P+Q+       GC PP             
Sbjct: 46  PAPMKTPEAGLAGRPSPWTTPGRAAATVPAAPMQLFNG----GCPPPPPVLDGEDVLPDL 101

Query: 189 SQASGPLPGPHFPLPGRGEVWGPGYRSQREPGPGAKEEAAGVSGPAGRGRGGEHGPQV-- 246
                P P P   LP   E   P   S       A  E   +S P    +    GP V  
Sbjct: 102 DLLPPPPPPPPVLLPSEEEAPAPMGASLI-----ADLEQLHLSPPPPPPQAPAEGPSVQP 156

Query: 247 -PLSQPPEDELDRLTKKLVHDMNHPPSGEYFGQCGGCGEDVVGDGAGVVALDRVFHVGCF 305
            PL +P E+EL     + V        G     C  C + V      V A+ R +H  CF
Sbjct: 157 GPL-RPMEEELPPPPAEPVE------KGASTDICAFCHKTVSPRELAVEAMKRQYHAQCF 209

Query: 306 VCSTCRAQLRGQHFYAVERRAYCEGCYVATLEKCATCSQPILDRILRAMGKAYHPGCFTC 365
            C TCR QL GQ FY  + R  CE CY  TLE+C  C + + D I+RA+G+A+HP CFTC
Sbjct: 210 TCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLERCGKCGEVVRDHIIRALGQAFHPSCFTC 269

Query: 366 VVCHRGLDGIPFTVDATSQIHCIEDFHRKFAPRCSVCGGAIMPEPGQEETVRIVALDRSF 425
           V C R +    F + + ++++C++DF+RKFAP CS+C   I+P  G ++  +I  + R+F
Sbjct: 270 VTCARCIGDESFALGSQNEVYCLDDFYRKFAPVCSICENPIIPRDG-KDAFKIECMGRNF 328

Query: 426 HIGCYKCEECGLLLSSEGECQGCYPLDGHILCKACSAWR 464
           H  CY+CE+C +LLS E   QGCYPL+ H+ CK C   R
Sbjct: 329 HENCYRCEDCRILLSVEPTDQGCYPLNNHLFCKPCHVKR 367


>gi|66932988 filamin-binding LIM protein-1 isoform c [Homo sapiens]
          Length = 276

 Score =  192 bits (487), Expect = 7e-49
 Identities = 83/186 (44%), Positives = 116/186 (62%), Gaps = 1/186 (0%)

Query: 279 CGGCGEDVVGDGAGVVALDRVFHVGCFVCSTCRAQLRGQHFYAVERRAYCEGCYVATLEK 338
           C  C + V      V A+ R +H  CF C TCR QL GQ FY  + R  CE CY  TLE+
Sbjct: 86  CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLER 145

Query: 339 CATCSQPILDRILRAMGKAYHPGCFTCVVCHRGLDGIPFTVDATSQIHCIEDFHRKFAPR 398
           C  C + + D I+RA+G+A+HP CFTCV C R +    F + + ++++C++DF+RKFAP 
Sbjct: 146 CGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAPV 205

Query: 399 CSVCGGAIMPEPGQEETVRIVALDRSFHIGCYKCEECGLLLSSEGECQGCYPLDGHILCK 458
           CS+C   I+P  G ++  +I  + R+FH  CY+CE+C +LLS E   QGCYPL+ H+ CK
Sbjct: 206 CSICENPIIPRDG-KDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLFCK 264

Query: 459 ACSAWR 464
            C   R
Sbjct: 265 PCHVKR 270


>gi|37675280 ajuba isoform 2 [Homo sapiens]
          Length = 121

 Score =  150 bits (379), Expect = 2e-36
 Identities = 58/112 (51%), Positives = 84/112 (75%), Gaps = 1/112 (0%)

Query: 354 MGKAYHPGCFTCVVCHRGLDGIPFTVDATSQIHCIEDFHRKFAPRCSVCGGAIMPEPGQE 413
           MGK+YHPGCF C+VC++ LDGIPFTVD ++Q++C+ D+H+ +AP+C+ CG  I+P  G E
Sbjct: 1   MGKSYHPGCFRCIVCNKCLDGIPFTVDFSNQVYCVTDYHKNYAPKCAACGQPILPSEGCE 60

Query: 414 ETVRIVALDRSFHIGCYKCEECGLLLSSEGECQGCYPLDGHILCKACSAWRI 465
           + VR++++DR +H  CY CE+C + LS E  C  C+PLDGH+LC  C   R+
Sbjct: 61  DIVRVISMDRDYHFECYHCEDCRMQLSDEEGC-CCFPLDGHLLCHGCHMQRL 111



 Score = 42.7 bits (99), Expect = 7e-04
 Identities = 29/86 (33%), Positives = 38/86 (44%), Gaps = 9/86 (10%)

Query: 296 LDRVFHVGCFVCSTCRAQLRGQHFYA-VERRAYCEGCYVAT-LEKCATCSQPIL-----D 348
           + + +H GCF C  C   L G  F      + YC   Y      KCA C QPIL     +
Sbjct: 1   MGKSYHPGCFRCIVCNKCLDGIPFTVDFSNQVYCVTDYHKNYAPKCAACGQPILPSEGCE 60

Query: 349 RILR--AMGKAYHPGCFTCVVCHRGL 372
            I+R  +M + YH  C+ C  C   L
Sbjct: 61  DIVRVISMDRDYHFECYHCEDCRMQL 86



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 20/70 (28%), Positives = 34/70 (48%), Gaps = 8/70 (11%)

Query: 275 YFGQCGGCGEDVVG-----DGAGVVALDRVFHVGCFVCSTCRAQL---RGQHFYAVERRA 326
           Y  +C  CG+ ++      D   V+++DR +H  C+ C  CR QL    G   + ++   
Sbjct: 42  YAPKCAACGQPILPSEGCEDIVRVISMDRDYHFECYHCEDCRMQLSDEEGCCCFPLDGHL 101

Query: 327 YCEGCYVATL 336
            C GC++  L
Sbjct: 102 LCHGCHMQRL 111


>gi|66932986 filamin-binding LIM protein-1 isoform b [Homo sapiens]
          Length = 374

 Score =  125 bits (315), Expect = 6e-29
 Identities = 95/317 (29%), Positives = 133/317 (41%), Gaps = 35/317 (11%)

Query: 138 PNPASPLPASPYGGPTPASYTTASTPAGPAFPVQVKVAQPVRGCGPPRR---------GA 188
           P P     A   G P+P +    +    PA P+Q+       GC PP             
Sbjct: 46  PAPMKTPEAGLAGRPSPWTTPGRAAATVPAAPMQLFNG----GCPPPPPVLDGEDVLPDL 101

Query: 189 SQASGPLPGPHFPLPGRGEVWGPGYRSQREPGPGAKEEAAGVSGPAGRGRGGEHGPQV-- 246
                P P P   LP   E   P   S       A  E   +S P    +    GP V  
Sbjct: 102 DLLPPPPPPPPVLLPSEEEAPAPMGASLI-----ADLEQLHLSPPPPPPQAPAEGPSVQP 156

Query: 247 -PLSQPPEDELDRLTKKLVHDMNHPPSGEYFGQCGGCGEDVVGDGAGVVALDRVFHVGCF 305
            PL +P E+EL     + V        G     C  C + V      V A+ R +H  CF
Sbjct: 157 GPL-RPMEEELPPPPAEPVE------KGASTDICAFCHKTVSPRELAVEAMKRQYHAQCF 209

Query: 306 VCSTCRAQLRGQHFYAVERRAYCEGCYVATLEKCATCSQPILDRILRAMGKAYHPGCFTC 365
            C TCR QL GQ FY  + R  CE CY  TLE+C  C + + D I+RA+G+A+HP CFTC
Sbjct: 210 TCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLERCGKCGEVVRDHIIRALGQAFHPSCFTC 269

Query: 366 VVCHRGLDGIPFTVDATSQIHCIEDFHRKFAPRCSVCGGAIMPEPGQEETVRIVALDRSF 425
           V C R +    F + + ++++C++DF+R     C+  G     +P + +       + S 
Sbjct: 270 VTCARCIGDESFALGSQNEVYCLDDFYRYEKGLCTGWGAGTGRDPSRVK-------ELSL 322

Query: 426 HIGCYKCEECGLLLSSE 442
             GC+    C L+   E
Sbjct: 323 SPGCWARVSCLLVYYKE 339



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 43/153 (28%), Positives = 63/153 (41%), Gaps = 26/153 (16%)

Query: 334 ATLEKCATCSQPILDRIL--RAMGKAYHPGCFTCVVCHRGLDGIPFTVDATSQIHCIEDF 391
           A+ + CA C + +  R L   AM + YH  CFTC  C R L G  F       +   E  
Sbjct: 178 ASTDICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPL--CEPC 235

Query: 392 HRKFAPRCSVCGGAIMPEPGQEETVRIVALDRSFHIGCYKCEECGLLLSSE----GECQG 447
           ++    RC  CG  +     ++  +R  AL ++FH  C+ C  C   +  E    G    
Sbjct: 236 YQDTLERCGKCGEVV-----RDHIIR--ALGQAFHPSCFTCVTCARCIGDESFALGSQNE 288

Query: 448 CYPLDGHILCK--ACSAW---------RIQELS 469
            Y LD     +   C+ W         R++ELS
Sbjct: 289 VYCLDDFYRYEKGLCTGWGAGTGRDPSRVKELS 321


>gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens]
          Length = 617

 Score =  101 bits (252), Expect = 1e-21
 Identities = 91/352 (25%), Positives = 133/352 (37%), Gaps = 44/352 (12%)

Query: 126 PPPPAYRTGSLKPNPASPLPASPYGGP-----TPASYTTASTPAGPAFPVQVKVAQPVRG 180
           P P    T S++P+   P+PAS Y        +P  YT +  PA    P       PV  
Sbjct: 283 PKPRVVTTASIRPSVYQPVPASTYSPSPGANYSPTPYTPSPAPAYTPSPAPAYTPSPVPT 342

Query: 181 CGPPRRGASQASGPLPGPHF-PLPGRGEVWGPGYRSQREP-----------GPGAKEEAA 228
             P     + A  P P P++ P P      GP   + R P            PG    + 
Sbjct: 343 YTP---SPAPAYTPSPAPNYNPAPSVAYSGGPAEPASRPPWVTDDSFSQKFAPGKSTTSI 399

Query: 229 GVSG-PAGRGRGGEHGPQVPLSQPPEDELDRLTKKLVHDMNHPPSGEYFGQCGGCGEDVV 287
                P G       GPQVP           L +  V      P+      CG C   + 
Sbjct: 400 SKQTLPRGGPAYTPAGPQVP----------PLARGTVQRAERFPASSRTPLCGHCNNVI- 448

Query: 288 GDGAGVVALDRVFHVGCFVCSTCRAQLRGQHFYAVERRAYCEGCYVATLEK-CATCSQPI 346
             G  +VA+ R +H   F C+ C+  L    F   +   YCE CY       CA C+  I
Sbjct: 449 -RGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKI 507

Query: 347 LDRILRAMGKAYHPGCFTCVVCHRGLDGIPFTVDATSQIHCIEDFHRKFAPRCSVCGGAI 406
           +  ++ A+ + +H  CF C  C +      F ++   + +C +D+   F+ +C  C   +
Sbjct: 508 MGEVMHALRQTWHTTCFVCAACKKPFGNSLFHME-DGEPYCEKDYINLFSTKCHGCDFPV 566

Query: 407 MPEPGQEETVRIVALDRSFHIGCYKCEECGLLLSSEGECQGCYPLDGHILCK 458
             E G +    I AL  ++H  C+ C  C + L    E Q  Y      LCK
Sbjct: 567 --EAGDK---FIEALGHTWHDTCFICAVCHVNL----EGQPFYSKKDRPLCK 609



 Score = 38.5 bits (88), Expect = 0.013
 Identities = 24/66 (36%), Positives = 28/66 (42%), Gaps = 5/66 (7%)

Query: 4   PTWLPPKQPEPARAPQGRAIPRGTPGPPPAHGAALQPHPRVNFCPLPSEQCYQAPGGPED 63
           P+  P   P PA A     +P  TP P PA+     P P  N+ P PS      P  P  
Sbjct: 321 PSPAPAYTPSPAPAYTPSPVPTYTPSPAPAY----TPSPAPNYNPAPSVAYSGGPAEPAS 376

Query: 64  RGPAWV 69
           R P WV
Sbjct: 377 R-PPWV 381


>gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]
          Length = 727

 Score =  101 bits (252), Expect = 1e-21
 Identities = 91/352 (25%), Positives = 133/352 (37%), Gaps = 44/352 (12%)

Query: 126 PPPPAYRTGSLKPNPASPLPASPYGGP-----TPASYTTASTPAGPAFPVQVKVAQPVRG 180
           P P    T S++P+   P+PAS Y        +P  YT +  PA    P       PV  
Sbjct: 393 PKPRVVTTASIRPSVYQPVPASTYSPSPGANYSPTPYTPSPAPAYTPSPAPAYTPSPVPT 452

Query: 181 CGPPRRGASQASGPLPGPHF-PLPGRGEVWGPGYRSQREP-----------GPGAKEEAA 228
             P     + A  P P P++ P P      GP   + R P            PG    + 
Sbjct: 453 YTP---SPAPAYTPSPAPNYNPAPSVAYSGGPAEPASRPPWVTDDSFSQKFAPGKSTTSI 509

Query: 229 GVSG-PAGRGRGGEHGPQVPLSQPPEDELDRLTKKLVHDMNHPPSGEYFGQCGGCGEDVV 287
                P G       GPQVP           L +  V      P+      CG C   + 
Sbjct: 510 SKQTLPRGGPAYTPAGPQVP----------PLARGTVQRAERFPASSRTPLCGHCNNVI- 558

Query: 288 GDGAGVVALDRVFHVGCFVCSTCRAQLRGQHFYAVERRAYCEGCYVATLEK-CATCSQPI 346
             G  +VA+ R +H   F C+ C+  L    F   +   YCE CY       CA C+  I
Sbjct: 559 -RGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKI 617

Query: 347 LDRILRAMGKAYHPGCFTCVVCHRGLDGIPFTVDATSQIHCIEDFHRKFAPRCSVCGGAI 406
           +  ++ A+ + +H  CF C  C +      F ++   + +C +D+   F+ +C  C   +
Sbjct: 618 MGEVMHALRQTWHTTCFVCAACKKPFGNSLFHME-DGEPYCEKDYINLFSTKCHGCDFPV 676

Query: 407 MPEPGQEETVRIVALDRSFHIGCYKCEECGLLLSSEGECQGCYPLDGHILCK 458
             E G +    I AL  ++H  C+ C  C + L    E Q  Y      LCK
Sbjct: 677 --EAGDK---FIEALGHTWHDTCFICAVCHVNL----EGQPFYSKKDRPLCK 719



 Score = 38.5 bits (88), Expect = 0.013
 Identities = 24/66 (36%), Positives = 28/66 (42%), Gaps = 5/66 (7%)

Query: 4   PTWLPPKQPEPARAPQGRAIPRGTPGPPPAHGAALQPHPRVNFCPLPSEQCYQAPGGPED 63
           P+  P   P PA A     +P  TP P PA+     P P  N+ P PS      P  P  
Sbjct: 431 PSPAPAYTPSPAPAYTPSPVPTYTPSPAPAY----TPSPAPNYNPAPSVAYSGGPAEPAS 486

Query: 64  RGPAWV 69
           R P WV
Sbjct: 487 R-PPWV 491


>gi|170932516 paxillin isoform 2 [Homo sapiens]
          Length = 557

 Score =  100 bits (249), Expect = 3e-21
 Identities = 120/501 (23%), Positives = 187/501 (37%), Gaps = 74/501 (14%)

Query: 8   PPKQPEPARAPQGRAIPRGTPGPPPA---HGAALQPHPRVNFCPLPSEQCYQAP------ 58
           P   P      Q  A+P   P PP +   +G  L P  +  + P  S   +Q P      
Sbjct: 30  PYSYPTGNHTYQEIAVPPPVPPPPSSEALNGTILDPLDQ--WQPSSSRFIHQQPQSSSPV 87

Query: 59  ----------GGPEDRGPAWVGSHGVLQHTQGLPADRGGLRPG------SLDAEIDLLSS 102
                       P+D   +     G  +H    P  +    P       SL + +  L  
Sbjct: 88  YGSSAKTSSVSNPQDSVGSPCSRVGEEEHVYSFPNKQKSAEPSPTVMSTSLGSNLSELDR 147

Query: 103 TLAELNGGRGHASRRPDRQAYEPPPPPAYRTGSLKPNPASPLPASPYGGPT-PASYTTAS 161
            L ELN  + +    P  +A   PP P    G+L P    P   SP GG   P +     
Sbjct: 148 LLLELNAVQHNPPGFPADEANSSPPLP----GALSPLYGVPETNSPLGGKAGPLTKEKPK 203

Query: 162 TPAGPAFPVQVKVAQPVRGCGPPRRGASQASGPLPGPHFPLPGRGEVWGPG-----YRSQ 216
              G          + VR          ++S P P P   +  +GE+  P       +  
Sbjct: 204 RNGGRGL-------EDVRPSVESLLDELESSVPSPVPAITV-NQGEMSSPQRVTSTQQQT 255

Query: 217 REPGPGAKEEAAGVSGPAGRGR---GGEHGPQVPLSQPPE--DELDRLTKKLVHDMNHPP 271
           R     A  E   +       +    G+ G   P   PP+   +LD +   L  D+N   
Sbjct: 256 RISASSATRELDELMASLSDFKFMAQGKTGSSSPPGGPPKPGSQLDSMLGSLQSDLNKLG 315

Query: 272 SGEYF-GQCGGCGEDVVGDGAGVVALDRVFHVGCFVCSTCRAQLRGQHFYAVERRAYCEG 330
                 G CG C + + G    V A+ + +H   FVC+ C+ ++  ++F+  + + YCE 
Sbjct: 316 VATVAKGVCGACKKPIAGQV--VTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEK 373

Query: 331 CYVATLE-KCATCSQPILDRILRAMGKAYHPGCFTCVVCHR--GLDGIPFTVDATSQIHC 387
            Y      +C  C+ PILD+++ A+ + +HP  F C  C    G +G     +   + +C
Sbjct: 374 DYHNLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFH---EKDGKAYC 430

Query: 388 IEDFHRKFAPRCSVCGGAIMPEPGQEETVRIVALDRSFHIGCYKCEEC------GLLLSS 441
            +D+   FAP+C  C  AI+          I AL+  +H  C+ C EC      G     
Sbjct: 431 RKDYFDMFAPKCGGCARAILEN-------YISALNTLWHPECFVCRECFTPFVNGSFFEH 483

Query: 442 EGE--CQGCYPLDGHILCKAC 460
           +G+  C+  Y      LC  C
Sbjct: 484 DGQPYCEVHYHERRGSLCSGC 504



 Score = 60.5 bits (145), Expect = 3e-09
 Identities = 31/97 (31%), Positives = 48/97 (49%), Gaps = 3/97 (3%)

Query: 278 QCGGCGEDVVGDGAGVVALDRVFHVGCFVCSTCRAQLRGQHFYAVERRAYCEGCYVATLE 337
           +CGGC   ++ +   + AL+ ++H  CFVC  C        F+  + + YCE  Y     
Sbjct: 441 KCGGCARAILENY--ISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRG 498

Query: 338 K-CATCSQPILDRILRAMGKAYHPGCFTCVVCHRGLD 373
             C+ C +PI  R + AM K +HP  F C  C + L+
Sbjct: 499 SLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLN 535



 Score = 37.7 bits (86), Expect = 0.023
 Identities = 17/55 (30%), Positives = 27/55 (49%), Gaps = 2/55 (3%)

Query: 279 CGGCGEDVVGDGAGVVALDRVFHVGCFVCSTCRAQLRGQHFYAVERRAYCEGCYV 333
           C GC + + G    + A+ + FH   FVC+ C  QL    F     + YC+ C++
Sbjct: 501 CSGCQKPITG--RCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFL 553


>gi|170932514 paxillin isoform 1 [Homo sapiens]
          Length = 591

 Score =  100 bits (248), Expect = 4e-21
 Identities = 130/533 (24%), Positives = 201/533 (37%), Gaps = 104/533 (19%)

Query: 8   PPKQPEPARAPQGRAIPRGTPGPPPA---HGAALQPHPRVNFCPLPSEQCYQAP------ 58
           P   P      Q  A+P   P PP +   +G  L P  +  + P  S   +Q P      
Sbjct: 30  PYSYPTGNHTYQEIAVPPPVPPPPSSEALNGTILDPLDQ--WQPSSSRFIHQQPQSSSPV 87

Query: 59  ----------GGPEDRGPAWVGSHGVLQHTQGLPADRGGLRPG------SLDAEIDLLSS 102
                       P+D   +     G  +H    P  +    P       SL + +  L  
Sbjct: 88  YGSSAKTSSVSNPQDSVGSPCSRVGEEEHVYSFPNKQKSAEPSPTVMSTSLGSNLSELDR 147

Query: 103 TLAELNGGRGHASRRPDRQAYEPPPPPAYRTGSLKPNPASPLPASPYGG----------- 151
            L ELN  + +    P  +A   PP P    G+L P    P   SP GG           
Sbjct: 148 LLLELNAVQHNPPGFPADEANSSPPLP----GALSPLYGVPETNSPLGGKAGPLTKEKPK 203

Query: 152 -----------PTPASYTT---ASTPAG-PAFPV-QVKVAQPVRGCGPPRR---GASQAS 192
                      P+  S      +S P+  PA  V Q +++ P R     ++    AS A+
Sbjct: 204 RNGGRGLEDVRPSVESLLDELESSVPSPVPAITVNQGEMSSPQRVTSTQQQTRISASSAT 263

Query: 193 GPLPG-----PHFPLPGRGE------VWGPGY-RSQREPGPGAKEEAAGVSGPAGRGRGG 240
             L         F + G  +       W  G+ R      PG ++E     G   +G+ G
Sbjct: 264 RELDELMASLSDFKIQGLEQRADGERCWAAGWPRDGGRSSPGGQDEG----GFMAQGKTG 319

Query: 241 EHGPQVPLSQP-PEDELDRLTKKLVHDMNHPPSGEYF-GQCGGCGEDVVGDGAGVVALDR 298
              P  P   P P  +LD +   L  D+N         G CG C + + G    V A+ +
Sbjct: 320 SSSP--PGGPPKPGSQLDSMLGSLQSDLNKLGVATVAKGVCGACKKPIAGQV--VTAMGK 375

Query: 299 VFHVGCFVCSTCRAQLRGQHFYAVERRAYCEGCYVATLE-KCATCSQPILDRILRAMGKA 357
            +H   FVC+ C+ ++  ++F+  + + YCE  Y      +C  C+ PILD+++ A+ + 
Sbjct: 376 TWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTALDRT 435

Query: 358 YHPGCFTCVVCHR--GLDGIPFTVDATSQIHCIEDFHRKFAPRCSVCGGAIMPEPGQEET 415
           +HP  F C  C    G +G     +   + +C +D+   FAP+C  C  AI+        
Sbjct: 436 WHPEHFFCAQCGAFFGPEGFH---EKDGKAYCRKDYFDMFAPKCGGCARAILEN------ 486

Query: 416 VRIVALDRSFHIGCYKCEEC------GLLLSSEGE--CQGCYPLDGHILCKAC 460
             I AL+  +H  C+ C EC      G     +G+  C+  Y      LC  C
Sbjct: 487 -YISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGC 538



 Score = 60.5 bits (145), Expect = 3e-09
 Identities = 31/97 (31%), Positives = 48/97 (49%), Gaps = 3/97 (3%)

Query: 278 QCGGCGEDVVGDGAGVVALDRVFHVGCFVCSTCRAQLRGQHFYAVERRAYCEGCYVATLE 337
           +CGGC   ++ +   + AL+ ++H  CFVC  C        F+  + + YCE  Y     
Sbjct: 475 KCGGCARAILENY--ISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRG 532

Query: 338 K-CATCSQPILDRILRAMGKAYHPGCFTCVVCHRGLD 373
             C+ C +PI  R + AM K +HP  F C  C + L+
Sbjct: 533 SLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLN 569



 Score = 37.7 bits (86), Expect = 0.023
 Identities = 17/55 (30%), Positives = 27/55 (49%), Gaps = 2/55 (3%)

Query: 279 CGGCGEDVVGDGAGVVALDRVFHVGCFVCSTCRAQLRGQHFYAVERRAYCEGCYV 333
           C GC + + G    + A+ + FH   FVC+ C  QL    F     + YC+ C++
Sbjct: 535 CSGCQKPITG--RCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFL 587


>gi|170932518 paxillin isoform 3 [Homo sapiens]
          Length = 424

 Score = 97.1 bits (240), Expect = 3e-20
 Identities = 99/392 (25%), Positives = 156/392 (39%), Gaps = 47/392 (11%)

Query: 92  SLDAEIDLLSSTLAELNGGRGHASRRPDRQAYEPPPPPAYRTGSLKPNPASPLPASPYGG 151
           SL + +  L   L ELN  + +    P  +A   PP P    G+L P    P   SP GG
Sbjct: 4   SLGSNLSELDRLLLELNAVQHNPPGFPADEANSSPPLP----GALSPLYGVPETNSPLGG 59

Query: 152 PT-PASYTTASTPAGPAFPVQVKVAQPVRGCGPPRRGASQASGPLPGPHFPLPGRGEVWG 210
              P +        G          + VR          ++S P P P   +  +GE+  
Sbjct: 60  KAGPLTKEKPKRNGGRGL-------EDVRPSVESLLDELESSVPSPVPAITV-NQGEMSS 111

Query: 211 PG-----YRSQREPGPGAKEEAAGVSGPAGRGR---GGEHGPQVPLSQPPE--DELDRLT 260
           P       +  R     A  E   +       +    G+ G   P   PP+   +LD + 
Sbjct: 112 PQRVTSTQQQTRISASSATRELDELMASLSDFKFMAQGKTGSSSPPGGPPKPGSQLDSML 171

Query: 261 KKLVHDMNHPPSGEYF-GQCGGCGEDVVGDGAGVVALDRVFHVGCFVCSTCRAQLRGQHF 319
             L  D+N         G CG C + + G    V A+ + +H   FVC+ C+ ++  ++F
Sbjct: 172 GSLQSDLNKLGVATVAKGVCGACKKPIAGQV--VTAMGKTWHPEHFVCTHCQEEIGSRNF 229

Query: 320 YAVERRAYCEGCYVATLE-KCATCSQPILDRILRAMGKAYHPGCFTCVVCHR--GLDGIP 376
           +  + + YCE  Y      +C  C+ PILD+++ A+ + +HP  F C  C    G +G  
Sbjct: 230 FERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFH 289

Query: 377 FTVDATSQIHCIEDFHRKFAPRCSVCGGAIMPEPGQEETVRIVALDRSFHIGCYKCEEC- 435
              +   + +C +D+   FAP+C  C  AI+          I AL+  +H  C+ C EC 
Sbjct: 290 ---EKDGKAYCRKDYFDMFAPKCGGCARAILEN-------YISALNTLWHPECFVCRECF 339

Query: 436 -----GLLLSSEGE--CQGCYPLDGHILCKAC 460
                G     +G+  C+  Y      LC  C
Sbjct: 340 TPFVNGSFFEHDGQPYCEVHYHERRGSLCSGC 371



 Score = 60.5 bits (145), Expect = 3e-09
 Identities = 31/97 (31%), Positives = 48/97 (49%), Gaps = 3/97 (3%)

Query: 278 QCGGCGEDVVGDGAGVVALDRVFHVGCFVCSTCRAQLRGQHFYAVERRAYCEGCYVATLE 337
           +CGGC   ++ +   + AL+ ++H  CFVC  C        F+  + + YCE  Y     
Sbjct: 308 KCGGCARAILENY--ISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRG 365

Query: 338 K-CATCSQPILDRILRAMGKAYHPGCFTCVVCHRGLD 373
             C+ C +PI  R + AM K +HP  F C  C + L+
Sbjct: 366 SLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLN 402



 Score = 37.7 bits (86), Expect = 0.023
 Identities = 17/55 (30%), Positives = 27/55 (49%), Gaps = 2/55 (3%)

Query: 279 CGGCGEDVVGDGAGVVALDRVFHVGCFVCSTCRAQLRGQHFYAVERRAYCEGCYV 333
           C GC + + G    + A+ + FH   FVC+ C  QL    F     + YC+ C++
Sbjct: 368 CSGCQKPITG--RCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFL 420


>gi|109638745 transforming growth factor beta 1 induced transcript 1
           isoform 1 [Homo sapiens]
          Length = 461

 Score = 95.1 bits (235), Expect = 1e-19
 Identities = 60/193 (31%), Positives = 82/193 (42%), Gaps = 19/193 (9%)

Query: 277 GQCGGCGEDVVGDGAGVVALDRVFHVGCFVCSTCRAQLRGQHFYAVERRAYCEGCYVATL 336
           G CG C + + G    V AL R +H   FVC  C   L G  F+  +   +C  CY    
Sbjct: 226 GLCGSCNKPIAGQV--VTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERF 283

Query: 337 E-KCATCSQPILDRILRAMGKAYHPGCFTCVVCHRGLDGIPFTVDATSQIHCIEDFHRKF 395
             +C  C+QPI  +++ A+G  +HP  F CV C        F  +   + +C  DF + F
Sbjct: 284 SPRCGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFH-EREGRPYCRRDFLQLF 342

Query: 396 APRCSVCGGAIMPEPGQEETVRIVALDRSFHIGCYKCEEC------GLLLSSEGE--CQG 447
           APRC  C G I+          I AL   +H  C+ C EC      G     EG   C+ 
Sbjct: 343 APRCQGCQGPILDN-------YISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCEN 395

Query: 448 CYPLDGHILCKAC 460
            +      LC  C
Sbjct: 396 HFHARRGSLCATC 408



 Score = 67.8 bits (164), Expect = 2e-11
 Identities = 50/181 (27%), Positives = 73/181 (40%), Gaps = 19/181 (10%)

Query: 278 QCGGCGEDVVGDGAGVVALDRVFHVGCFVCSTCRAQLRGQHFYAVERRAYCEGCYVATLE 337
           +CG C + +      V AL   +H   F C +C      + F+  E R YC   ++    
Sbjct: 286 RCGFCNQPI--RHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFA 343

Query: 338 -KCATCSQPILDRILRAMGKAYHPGCFTCVVCHRGLDGIPFTVDATSQIHCIEDFHRKFA 396
            +C  C  PILD  + A+   +HP CF C  C     G  F  +   +  C   FH +  
Sbjct: 344 PRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSF-FEHEGRPLCENHFHARRG 402

Query: 397 PRCSVCGGAIMPEPGQEETVRIVALDRSFHIGCYKCEEC------GLLLSSEGE--CQGC 448
             C+ CG   +P  G+     + AL R FH   + C  C      G      G+  CQ C
Sbjct: 403 SLCATCG---LPVTGR----CVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPC 455

Query: 449 Y 449
           +
Sbjct: 456 F 456



 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 45/158 (28%), Positives = 62/158 (39%), Gaps = 36/158 (22%)

Query: 339 CATCSQPILDRILRAMGKAYHPGCFTCVVCHRGLDGIPFTVDATSQIHCIEDFHRKFAPR 398
           C +C++PI  +++ A+G+A+HP  F C  C   L G  F  +      C E +  +F+PR
Sbjct: 228 CGSCNKPIAGQVVTALGRAWHPEHFVCGGCSTALGGSSF-FEKDGAPFCPECYFERFSPR 286

Query: 399 CSVCGGAIMPEPGQEETVRIVALDRSFHIGCYKCEECGLLLSSEG--------------- 443
           C  C   I  +        + AL   +H   + C  CG     EG               
Sbjct: 287 CGFCNQPIRHK-------MVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFL 339

Query: 444 -----ECQGCYPLDGHILCKACSAWRIQELSATVTTDC 476
                 CQGC    G IL    SA     LSA    DC
Sbjct: 340 QLFAPRCQGC---QGPILDNYISA-----LSALWHPDC 369



 Score = 33.5 bits (75), Expect = 0.43
 Identities = 19/55 (34%), Positives = 24/55 (43%), Gaps = 2/55 (3%)

Query: 279 CGGCGEDVVGDGAGVVALDRVFHVGCFVCSTCRAQLRGQHFYAVERRAYCEGCYV 333
           C  CG  V G    V AL R FH   F C+ C   L    F     + YC+ C++
Sbjct: 405 CATCGLPVTG--RCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPCFL 457


>gi|21361591 transforming growth factor beta 1 induced transcript 1
           isoform 2 [Homo sapiens]
          Length = 444

 Score = 95.1 bits (235), Expect = 1e-19
 Identities = 60/193 (31%), Positives = 82/193 (42%), Gaps = 19/193 (9%)

Query: 277 GQCGGCGEDVVGDGAGVVALDRVFHVGCFVCSTCRAQLRGQHFYAVERRAYCEGCYVATL 336
           G CG C + + G    V AL R +H   FVC  C   L G  F+  +   +C  CY    
Sbjct: 209 GLCGSCNKPIAGQV--VTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERF 266

Query: 337 E-KCATCSQPILDRILRAMGKAYHPGCFTCVVCHRGLDGIPFTVDATSQIHCIEDFHRKF 395
             +C  C+QPI  +++ A+G  +HP  F CV C        F  +   + +C  DF + F
Sbjct: 267 SPRCGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFH-EREGRPYCRRDFLQLF 325

Query: 396 APRCSVCGGAIMPEPGQEETVRIVALDRSFHIGCYKCEEC------GLLLSSEGE--CQG 447
           APRC  C G I+          I AL   +H  C+ C EC      G     EG   C+ 
Sbjct: 326 APRCQGCQGPILDN-------YISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCEN 378

Query: 448 CYPLDGHILCKAC 460
            +      LC  C
Sbjct: 379 HFHARRGSLCATC 391



 Score = 67.8 bits (164), Expect = 2e-11
 Identities = 50/181 (27%), Positives = 73/181 (40%), Gaps = 19/181 (10%)

Query: 278 QCGGCGEDVVGDGAGVVALDRVFHVGCFVCSTCRAQLRGQHFYAVERRAYCEGCYVATLE 337
           +CG C + +      V AL   +H   F C +C      + F+  E R YC   ++    
Sbjct: 269 RCGFCNQPI--RHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFA 326

Query: 338 -KCATCSQPILDRILRAMGKAYHPGCFTCVVCHRGLDGIPFTVDATSQIHCIEDFHRKFA 396
            +C  C  PILD  + A+   +HP CF C  C     G  F  +   +  C   FH +  
Sbjct: 327 PRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSF-FEHEGRPLCENHFHARRG 385

Query: 397 PRCSVCGGAIMPEPGQEETVRIVALDRSFHIGCYKCEEC------GLLLSSEGE--CQGC 448
             C+ CG   +P  G+     + AL R FH   + C  C      G      G+  CQ C
Sbjct: 386 SLCATCG---LPVTGR----CVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPC 438

Query: 449 Y 449
           +
Sbjct: 439 F 439



 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 45/158 (28%), Positives = 62/158 (39%), Gaps = 36/158 (22%)

Query: 339 CATCSQPILDRILRAMGKAYHPGCFTCVVCHRGLDGIPFTVDATSQIHCIEDFHRKFAPR 398
           C +C++PI  +++ A+G+A+HP  F C  C   L G  F  +      C E +  +F+PR
Sbjct: 211 CGSCNKPIAGQVVTALGRAWHPEHFVCGGCSTALGGSSF-FEKDGAPFCPECYFERFSPR 269

Query: 399 CSVCGGAIMPEPGQEETVRIVALDRSFHIGCYKCEECGLLLSSEG--------------- 443
           C  C   I  +        + AL   +H   + C  CG     EG               
Sbjct: 270 CGFCNQPIRHK-------MVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFL 322

Query: 444 -----ECQGCYPLDGHILCKACSAWRIQELSATVTTDC 476
                 CQGC    G IL    SA     LSA    DC
Sbjct: 323 QLFAPRCQGC---QGPILDNYISA-----LSALWHPDC 352



 Score = 33.5 bits (75), Expect = 0.43
 Identities = 19/55 (34%), Positives = 24/55 (43%), Gaps = 2/55 (3%)

Query: 279 CGGCGEDVVGDGAGVVALDRVFHVGCFVCSTCRAQLRGQHFYAVERRAYCEGCYV 333
           C  CG  V G    V AL R FH   F C+ C   L    F     + YC+ C++
Sbjct: 388 CATCGLPVTG--RCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPCFL 440


>gi|194272207 actin binding LIM protein family, member 2 isoform 7
           [Homo sapiens]
          Length = 470

 Score = 89.7 bits (221), Expect = 5e-18
 Identities = 64/214 (29%), Positives = 90/214 (42%), Gaps = 48/214 (22%)

Query: 279 CGGCGEDVVGDGAGVVALDRVFHVGCFVCSTCRAQLRGQHFYAVERRAYCEGCYVATLE- 337
           C  CG    G+   V   D+ FH+ CFVC  C   L    F+  +      G Y+ TL+ 
Sbjct: 24  CNTCGNVCKGEVLRVQ--DKYFHIKCFVCKACGCDLAEGGFFVRQ------GEYICTLDY 75

Query: 338 ------KCATCSQPILDRILRAMGKAYHPGCFTCVVCHRGL---DGIPFT---------- 378
                 +C +C Q I   ++ A+GK YHP CF C VC       D + F           
Sbjct: 76  QRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCS 135

Query: 379 --VDATSQIHCIEDFHRKFAPRCSVCGGAIMPEPGQEETVRIVALDRSFHIGCYKCEECG 436
             V   S  H  +         C  CG  I  + GQ     +VALD+ +H+GC+KC+ CG
Sbjct: 136 LPVSVGSSAHLSQGLR-----SCGGCGTEI--KNGQ----ALVALDKHWHLGCFKCKSCG 184

Query: 437 LLLSSE-------GECQGCYPLDGHILCKACSAW 463
            LL++E         C+  Y     I C +C  +
Sbjct: 185 KLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKY 218



 Score = 72.8 bits (177), Expect = 6e-13
 Identities = 36/91 (39%), Positives = 52/91 (57%), Gaps = 3/91 (3%)

Query: 279 CGGCGEDVVGDGAGVVALDRVFHVGCFVCSTCRAQLRGQHFYAVERRAYCEGCYVATLE- 337
           CGGCG ++  +G  +VALD+ +H+GCF C +C  +L    + + +   YCE  Y A    
Sbjct: 153 CGGCGTEIK-NGQALVALDKHWHLGCFKCKSC-GKLLNAEYISKDGLPYCEADYHAKFGI 210

Query: 338 KCATCSQPILDRILRAMGKAYHPGCFTCVVC 368
           +C +C + I  R+L A  K YHP C  CV C
Sbjct: 211 RCDSCEKYITGRVLEAGEKHYHPSCALCVRC 241


>gi|153792514 actin binding LIM protein family, member 2 isoform 6
           [Homo sapiens]
          Length = 521

 Score = 89.7 bits (221), Expect = 5e-18
 Identities = 64/214 (29%), Positives = 90/214 (42%), Gaps = 48/214 (22%)

Query: 279 CGGCGEDVVGDGAGVVALDRVFHVGCFVCSTCRAQLRGQHFYAVERRAYCEGCYVATLE- 337
           C  CG    G+   V   D+ FH+ CFVC  C   L    F+  +      G Y+ TL+ 
Sbjct: 24  CNTCGNVCKGEVLRVQ--DKYFHIKCFVCKACGCDLAEGGFFVRQ------GEYICTLDY 75

Query: 338 ------KCATCSQPILDRILRAMGKAYHPGCFTCVVCHRGL---DGIPFT---------- 378
                 +C +C Q I   ++ A+GK YHP CF C VC       D + F           
Sbjct: 76  QRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCS 135

Query: 379 --VDATSQIHCIEDFHRKFAPRCSVCGGAIMPEPGQEETVRIVALDRSFHIGCYKCEECG 436
             V   S  H  +         C  CG  I  + GQ     +VALD+ +H+GC+KC+ CG
Sbjct: 136 LPVSVGSSAHLSQGLR-----SCGGCGTEI--KNGQ----ALVALDKHWHLGCFKCKSCG 184

Query: 437 LLLSSE-------GECQGCYPLDGHILCKACSAW 463
            LL++E         C+  Y     I C +C  +
Sbjct: 185 KLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKY 218



 Score = 72.8 bits (177), Expect = 6e-13
 Identities = 36/91 (39%), Positives = 52/91 (57%), Gaps = 3/91 (3%)

Query: 279 CGGCGEDVVGDGAGVVALDRVFHVGCFVCSTCRAQLRGQHFYAVERRAYCEGCYVATLE- 337
           CGGCG ++  +G  +VALD+ +H+GCF C +C  +L    + + +   YCE  Y A    
Sbjct: 153 CGGCGTEIK-NGQALVALDKHWHLGCFKCKSC-GKLLNAEYISKDGLPYCEADYHAKFGI 210

Query: 338 KCATCSQPILDRILRAMGKAYHPGCFTCVVC 368
           +C +C + I  R+L A  K YHP C  CV C
Sbjct: 211 RCDSCEKYITGRVLEAGEKHYHPSCALCVRC 241


>gi|194272204 actin binding LIM protein family, member 2 isoform 5
           [Homo sapiens]
          Length = 531

 Score = 89.7 bits (221), Expect = 5e-18
 Identities = 64/214 (29%), Positives = 90/214 (42%), Gaps = 48/214 (22%)

Query: 279 CGGCGEDVVGDGAGVVALDRVFHVGCFVCSTCRAQLRGQHFYAVERRAYCEGCYVATLE- 337
           C  CG    G+   V   D+ FH+ CFVC  C   L    F+  +      G Y+ TL+ 
Sbjct: 24  CNTCGNVCKGEVLRVQ--DKYFHIKCFVCKACGCDLAEGGFFVRQ------GEYICTLDY 75

Query: 338 ------KCATCSQPILDRILRAMGKAYHPGCFTCVVCHRGL---DGIPFT---------- 378
                 +C +C Q I   ++ A+GK YHP CF C VC       D + F           
Sbjct: 76  QRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCS 135

Query: 379 --VDATSQIHCIEDFHRKFAPRCSVCGGAIMPEPGQEETVRIVALDRSFHIGCYKCEECG 436
             V   S  H  +         C  CG  I  + GQ     +VALD+ +H+GC+KC+ CG
Sbjct: 136 LPVSVGSSAHLSQGLR-----SCGGCGTEI--KNGQ----ALVALDKHWHLGCFKCKSCG 184

Query: 437 LLLSSE-------GECQGCYPLDGHILCKACSAW 463
            LL++E         C+  Y     I C +C  +
Sbjct: 185 KLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKY 218



 Score = 72.8 bits (177), Expect = 6e-13
 Identities = 36/91 (39%), Positives = 52/91 (57%), Gaps = 3/91 (3%)

Query: 279 CGGCGEDVVGDGAGVVALDRVFHVGCFVCSTCRAQLRGQHFYAVERRAYCEGCYVATLE- 337
           CGGCG ++  +G  +VALD+ +H+GCF C +C  +L    + + +   YCE  Y A    
Sbjct: 153 CGGCGTEIK-NGQALVALDKHWHLGCFKCKSC-GKLLNAEYISKDGLPYCEADYHAKFGI 210

Query: 338 KCATCSQPILDRILRAMGKAYHPGCFTCVVC 368
           +C +C + I  R+L A  K YHP C  CV C
Sbjct: 211 RCDSCEKYITGRVLEAGEKHYHPSCALCVRC 241


>gi|194272202 actin binding LIM protein family, member 2 isoform 4
           [Homo sapiens]
          Length = 559

 Score = 89.7 bits (221), Expect = 5e-18
 Identities = 64/214 (29%), Positives = 90/214 (42%), Gaps = 48/214 (22%)

Query: 279 CGGCGEDVVGDGAGVVALDRVFHVGCFVCSTCRAQLRGQHFYAVERRAYCEGCYVATLE- 337
           C  CG    G+   V   D+ FH+ CFVC  C   L    F+  +      G Y+ TL+ 
Sbjct: 24  CNTCGNVCKGEVLRVQ--DKYFHIKCFVCKACGCDLAEGGFFVRQ------GEYICTLDY 75

Query: 338 ------KCATCSQPILDRILRAMGKAYHPGCFTCVVCHRGL---DGIPFT---------- 378
                 +C +C Q I   ++ A+GK YHP CF C VC       D + F           
Sbjct: 76  QRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCS 135

Query: 379 --VDATSQIHCIEDFHRKFAPRCSVCGGAIMPEPGQEETVRIVALDRSFHIGCYKCEECG 436
             V   S  H  +         C  CG  I  + GQ     +VALD+ +H+GC+KC+ CG
Sbjct: 136 LPVSVGSSAHLSQGLR-----SCGGCGTEI--KNGQ----ALVALDKHWHLGCFKCKSCG 184

Query: 437 LLLSSE-------GECQGCYPLDGHILCKACSAW 463
            LL++E         C+  Y     I C +C  +
Sbjct: 185 KLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKY 218



 Score = 72.8 bits (177), Expect = 6e-13
 Identities = 36/91 (39%), Positives = 52/91 (57%), Gaps = 3/91 (3%)

Query: 279 CGGCGEDVVGDGAGVVALDRVFHVGCFVCSTCRAQLRGQHFYAVERRAYCEGCYVATLE- 337
           CGGCG ++  +G  +VALD+ +H+GCF C +C  +L    + + +   YCE  Y A    
Sbjct: 153 CGGCGTEIK-NGQALVALDKHWHLGCFKCKSC-GKLLNAEYISKDGLPYCEADYHAKFGI 210

Query: 338 KCATCSQPILDRILRAMGKAYHPGCFTCVVC 368
           +C +C + I  R+L A  K YHP C  CV C
Sbjct: 211 RCDSCEKYITGRVLEAGEKHYHPSCALCVRC 241


>gi|194272200 actin binding LIM protein family, member 2 isoform 3
           [Homo sapiens]
          Length = 572

 Score = 89.7 bits (221), Expect = 5e-18
 Identities = 64/214 (29%), Positives = 90/214 (42%), Gaps = 48/214 (22%)

Query: 279 CGGCGEDVVGDGAGVVALDRVFHVGCFVCSTCRAQLRGQHFYAVERRAYCEGCYVATLE- 337
           C  CG    G+   V   D+ FH+ CFVC  C   L    F+  +      G Y+ TL+ 
Sbjct: 24  CNTCGNVCKGEVLRVQ--DKYFHIKCFVCKACGCDLAEGGFFVRQ------GEYICTLDY 75

Query: 338 ------KCATCSQPILDRILRAMGKAYHPGCFTCVVCHRGL---DGIPFT---------- 378
                 +C +C Q I   ++ A+GK YHP CF C VC       D + F           
Sbjct: 76  QRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCS 135

Query: 379 --VDATSQIHCIEDFHRKFAPRCSVCGGAIMPEPGQEETVRIVALDRSFHIGCYKCEECG 436
             V   S  H  +         C  CG  I  + GQ     +VALD+ +H+GC+KC+ CG
Sbjct: 136 LPVSVGSSAHLSQGLR-----SCGGCGTEI--KNGQ----ALVALDKHWHLGCFKCKSCG 184

Query: 437 LLLSSE-------GECQGCYPLDGHILCKACSAW 463
            LL++E         C+  Y     I C +C  +
Sbjct: 185 KLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKY 218



 Score = 72.8 bits (177), Expect = 6e-13
 Identities = 36/91 (39%), Positives = 52/91 (57%), Gaps = 3/91 (3%)

Query: 279 CGGCGEDVVGDGAGVVALDRVFHVGCFVCSTCRAQLRGQHFYAVERRAYCEGCYVATLE- 337
           CGGCG ++  +G  +VALD+ +H+GCF C +C  +L    + + +   YCE  Y A    
Sbjct: 153 CGGCGTEIK-NGQALVALDKHWHLGCFKCKSC-GKLLNAEYISKDGLPYCEADYHAKFGI 210

Query: 338 KCATCSQPILDRILRAMGKAYHPGCFTCVVC 368
           +C +C + I  R+L A  K YHP C  CV C
Sbjct: 211 RCDSCEKYITGRVLEAGEKHYHPSCALCVRC 241


>gi|194272198 actin binding LIM protein family, member 2 isoform 2
           [Homo sapiens]
          Length = 611

 Score = 89.7 bits (221), Expect = 5e-18
 Identities = 64/214 (29%), Positives = 90/214 (42%), Gaps = 48/214 (22%)

Query: 279 CGGCGEDVVGDGAGVVALDRVFHVGCFVCSTCRAQLRGQHFYAVERRAYCEGCYVATLE- 337
           C  CG    G+   V   D+ FH+ CFVC  C   L    F+  +      G Y+ TL+ 
Sbjct: 24  CNTCGNVCKGEVLRVQ--DKYFHIKCFVCKACGCDLAEGGFFVRQ------GEYICTLDY 75

Query: 338 ------KCATCSQPILDRILRAMGKAYHPGCFTCVVCHRGL---DGIPFT---------- 378
                 +C +C Q I   ++ A+GK YHP CF C VC       D + F           
Sbjct: 76  QRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCS 135

Query: 379 --VDATSQIHCIEDFHRKFAPRCSVCGGAIMPEPGQEETVRIVALDRSFHIGCYKCEECG 436
             V   S  H  +         C  CG  I  + GQ     +VALD+ +H+GC+KC+ CG
Sbjct: 136 LPVSVGSSAHLSQGLR-----SCGGCGTEI--KNGQ----ALVALDKHWHLGCFKCKSCG 184

Query: 437 LLLSSE-------GECQGCYPLDGHILCKACSAW 463
            LL++E         C+  Y     I C +C  +
Sbjct: 185 KLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKY 218



 Score = 72.8 bits (177), Expect = 6e-13
 Identities = 36/91 (39%), Positives = 52/91 (57%), Gaps = 3/91 (3%)

Query: 279 CGGCGEDVVGDGAGVVALDRVFHVGCFVCSTCRAQLRGQHFYAVERRAYCEGCYVATLE- 337
           CGGCG ++  +G  +VALD+ +H+GCF C +C  +L    + + +   YCE  Y A    
Sbjct: 153 CGGCGTEIK-NGQALVALDKHWHLGCFKCKSC-GKLLNAEYISKDGLPYCEADYHAKFGI 210

Query: 338 KCATCSQPILDRILRAMGKAYHPGCFTCVVC 368
           +C +C + I  R+L A  K YHP C  CV C
Sbjct: 211 RCDSCEKYITGRVLEAGEKHYHPSCALCVRC 241


>gi|194272196 actin binding LIM protein family, member 2 isoform 1
           [Homo sapiens]
          Length = 645

 Score = 89.7 bits (221), Expect = 5e-18
 Identities = 64/214 (29%), Positives = 90/214 (42%), Gaps = 48/214 (22%)

Query: 279 CGGCGEDVVGDGAGVVALDRVFHVGCFVCSTCRAQLRGQHFYAVERRAYCEGCYVATLE- 337
           C  CG    G+   V   D+ FH+ CFVC  C   L    F+  +      G Y+ TL+ 
Sbjct: 24  CNTCGNVCKGEVLRVQ--DKYFHIKCFVCKACGCDLAEGGFFVRQ------GEYICTLDY 75

Query: 338 ------KCATCSQPILDRILRAMGKAYHPGCFTCVVCHRGL---DGIPFT---------- 378
                 +C +C Q I   ++ A+GK YHP CF C VC       D + F           
Sbjct: 76  QRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCS 135

Query: 379 --VDATSQIHCIEDFHRKFAPRCSVCGGAIMPEPGQEETVRIVALDRSFHIGCYKCEECG 436
             V   S  H  +         C  CG  I  + GQ     +VALD+ +H+GC+KC+ CG
Sbjct: 136 LPVSVGSSAHLSQGLR-----SCGGCGTEI--KNGQ----ALVALDKHWHLGCFKCKSCG 184

Query: 437 LLLSSE-------GECQGCYPLDGHILCKACSAW 463
            LL++E         C+  Y     I C +C  +
Sbjct: 185 KLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKY 218



 Score = 72.8 bits (177), Expect = 6e-13
 Identities = 36/91 (39%), Positives = 52/91 (57%), Gaps = 3/91 (3%)

Query: 279 CGGCGEDVVGDGAGVVALDRVFHVGCFVCSTCRAQLRGQHFYAVERRAYCEGCYVATLE- 337
           CGGCG ++  +G  +VALD+ +H+GCF C +C  +L    + + +   YCE  Y A    
Sbjct: 153 CGGCGTEIK-NGQALVALDKHWHLGCFKCKSC-GKLLNAEYISKDGLPYCEADYHAKFGI 210

Query: 338 KCATCSQPILDRILRAMGKAYHPGCFTCVVC 368
           +C +C + I  R+L A  K YHP C  CV C
Sbjct: 211 RCDSCEKYITGRVLEAGEKHYHPSCALCVRC 241


>gi|51173715 actin-binding LIM protein 1 isoform c [Homo sapiens]
          Length = 746

 Score = 89.0 bits (219), Expect = 9e-18
 Identities = 65/223 (29%), Positives = 99/223 (44%), Gaps = 39/223 (17%)

Query: 262 KLVHDMN-HPPSGEYFGQCGGCGEDVVGDGAGVVALDRVFHVGCFVCSTCRAQLRGQHFY 320
           K+ H  + H PS +    C  CGE   G+   V    + FH+ CF C  C   L    F+
Sbjct: 21  KVAHPQDPHHPSEKPVIHCHKCGEPCKGEVLRVQT--KHFHIKCFTCKVCGCDLAQGGFF 78

Query: 321 AVERRAYCEGCYVATLE-------KCATCSQPILDRILRAMGKAYHPGCFTCVVCHRGL- 372
                    G Y+ TL+       +C  C + +   ++ A+GK YHP CF C +C R   
Sbjct: 79  IKN------GEYLCTLDYQRMYGTRCHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFP 132

Query: 373 --DGIPFT-VDATSQIHCIEDF-----HRKFAPRCSVCGGAIMPEPGQEETVRIVALDRS 424
             D + F   D   Q+ C +          F+  C+ CG  I  + GQ     ++ALD+ 
Sbjct: 133 PGDRVTFNGRDCLCQL-CAQPMSSSPKETTFSSNCAGCGRDI--KNGQ----ALLALDKQ 185

Query: 425 FHIGCYKCEECGLLLSSE-------GECQGCYPLDGHILCKAC 460
           +H+GC+KC+ CG +L+ E         C+  Y     + C+AC
Sbjct: 186 WHLGCFKCKSCGKVLTGEYISKDGAPYCEKDYQGLFGVKCEAC 228



 Score = 73.6 bits (179), Expect = 4e-13
 Identities = 43/127 (33%), Positives = 62/127 (48%), Gaps = 9/127 (7%)

Query: 251 PPEDEL-----DRLTKKLVHDMNHPPSGEYFGQ-CGGCGEDVVGDGAGVVALDRVFHVGC 304
           PP D +     D L +     M+  P    F   C GCG D+  +G  ++ALD+ +H+GC
Sbjct: 132 PPGDRVTFNGRDCLCQLCAQPMSSSPKETTFSSNCAGCGRDIK-NGQALLALDKQWHLGC 190

Query: 305 FVCSTCRAQLRGQHFYAVERRAYCEGCYVATLE-KCATCSQPILDRILRAMGKAYHPGCF 363
           F C +C   L G++  + +   YCE  Y      KC  C Q I  ++L A  K YHP C 
Sbjct: 191 FKCKSCGKVLTGEYI-SKDGAPYCEKDYQGLFGVKCEACHQFITGKVLEAGDKHYHPSCA 249

Query: 364 TCVVCHR 370
            C  C++
Sbjct: 250 RCSRCNQ 256


>gi|51173713 actin-binding LIM protein 1 isoform b [Homo sapiens]
          Length = 718

 Score = 89.0 bits (219), Expect = 9e-18
 Identities = 65/223 (29%), Positives = 99/223 (44%), Gaps = 39/223 (17%)

Query: 262 KLVHDMN-HPPSGEYFGQCGGCGEDVVGDGAGVVALDRVFHVGCFVCSTCRAQLRGQHFY 320
           K+ H  + H PS +    C  CGE   G+   V    + FH+ CF C  C   L    F+
Sbjct: 21  KVAHPQDPHHPSEKPVIHCHKCGEPCKGEVLRVQT--KHFHIKCFTCKVCGCDLAQGGFF 78

Query: 321 AVERRAYCEGCYVATLE-------KCATCSQPILDRILRAMGKAYHPGCFTCVVCHRGL- 372
                    G Y+ TL+       +C  C + +   ++ A+GK YHP CF C +C R   
Sbjct: 79  IKN------GEYLCTLDYQRMYGTRCHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFP 132

Query: 373 --DGIPFT-VDATSQIHCIEDF-----HRKFAPRCSVCGGAIMPEPGQEETVRIVALDRS 424
             D + F   D   Q+ C +          F+  C+ CG  I  + GQ     ++ALD+ 
Sbjct: 133 PGDRVTFNGRDCLCQL-CAQPMSSSPKETTFSSNCAGCGRDI--KNGQ----ALLALDKQ 185

Query: 425 FHIGCYKCEECGLLLSSE-------GECQGCYPLDGHILCKAC 460
           +H+GC+KC+ CG +L+ E         C+  Y     + C+AC
Sbjct: 186 WHLGCFKCKSCGKVLTGEYISKDGAPYCEKDYQGLFGVKCEAC 228



 Score = 73.6 bits (179), Expect = 4e-13
 Identities = 43/127 (33%), Positives = 62/127 (48%), Gaps = 9/127 (7%)

Query: 251 PPEDEL-----DRLTKKLVHDMNHPPSGEYFGQ-CGGCGEDVVGDGAGVVALDRVFHVGC 304
           PP D +     D L +     M+  P    F   C GCG D+  +G  ++ALD+ +H+GC
Sbjct: 132 PPGDRVTFNGRDCLCQLCAQPMSSSPKETTFSSNCAGCGRDIK-NGQALLALDKQWHLGC 190

Query: 305 FVCSTCRAQLRGQHFYAVERRAYCEGCYVATLE-KCATCSQPILDRILRAMGKAYHPGCF 363
           F C +C   L G++  + +   YCE  Y      KC  C Q I  ++L A  K YHP C 
Sbjct: 191 FKCKSCGKVLTGEYI-SKDGAPYCEKDYQGLFGVKCEACHQFITGKVLEAGDKHYHPSCA 249

Query: 364 TCVVCHR 370
            C  C++
Sbjct: 250 RCSRCNQ 256


>gi|51173711 actin-binding LIM protein 1 isoform a [Homo sapiens]
          Length = 778

 Score = 88.2 bits (217), Expect = 1e-17
 Identities = 63/215 (29%), Positives = 95/215 (44%), Gaps = 38/215 (17%)

Query: 269 HPPSGEYFGQCGGCGEDVVGDGAGVVALDRVFHVGCFVCSTCRAQLRGQHFYAVERRAYC 328
           H PS +    C  CGE   G+   V    + FH+ CF C  C   L    F+        
Sbjct: 89  HHPSEKPVIHCHKCGEPCKGEVLRVQT--KHFHIKCFTCKVCGCDLAQGGFFIKN----- 141

Query: 329 EGCYVATLE-------KCATCSQPILDRILRAMGKAYHPGCFTCVVCHRGL---DGIPFT 378
            G Y+ TL+       +C  C + +   ++ A+GK YHP CF C +C R     D + F 
Sbjct: 142 -GEYLCTLDYQRMYGTRCHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFN 200

Query: 379 -VDATSQIHCIEDF-----HRKFAPRCSVCGGAIMPEPGQEETVRIVALDRSFHIGCYKC 432
             D   Q+ C +          F+  C+ CG  I  + GQ     ++ALD+ +H+GC+KC
Sbjct: 201 GRDCLCQL-CAQPMSSSPKETTFSSNCAGCGRDI--KNGQ----ALLALDKQWHLGCFKC 253

Query: 433 EECGLLLSSE-------GECQGCYPLDGHILCKAC 460
           + CG +L+ E         C+  Y     + C+AC
Sbjct: 254 KSCGKVLTGEYISKDGAPYCEKDYQGLFGVKCEAC 288



 Score = 73.6 bits (179), Expect = 4e-13
 Identities = 43/127 (33%), Positives = 62/127 (48%), Gaps = 9/127 (7%)

Query: 251 PPEDEL-----DRLTKKLVHDMNHPPSGEYFGQ-CGGCGEDVVGDGAGVVALDRVFHVGC 304
           PP D +     D L +     M+  P    F   C GCG D+  +G  ++ALD+ +H+GC
Sbjct: 192 PPGDRVTFNGRDCLCQLCAQPMSSSPKETTFSSNCAGCGRDIK-NGQALLALDKQWHLGC 250

Query: 305 FVCSTCRAQLRGQHFYAVERRAYCEGCYVATLE-KCATCSQPILDRILRAMGKAYHPGCF 363
           F C +C   L G++  + +   YCE  Y      KC  C Q I  ++L A  K YHP C 
Sbjct: 251 FKCKSCGKVLTGEYI-SKDGAPYCEKDYQGLFGVKCEACHQFITGKVLEAGDKHYHPSCA 309

Query: 364 TCVVCHR 370
            C  C++
Sbjct: 310 RCSRCNQ 316


>gi|54112385 four and a half LIM domains 3 [Homo sapiens]
          Length = 280

 Score = 87.0 bits (214), Expect = 3e-17
 Identities = 54/188 (28%), Positives = 78/188 (41%), Gaps = 9/188 (4%)

Query: 275 YFGQCGGCGEDVVGDGAGVVALDRVFHVGCFVCSTCRAQLRGQHFYAVERRAYCEGCYVA 334
           +  QC  CGE V+     +    + +H  CF+CS C   L  + F   +   YC  CY  
Sbjct: 97  FSSQCSACGETVMPGSRKLEYGGQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYEN 156

Query: 335 TL-EKCATCSQPILDRILRAMGKAYHPGCFTCVVCHRGLDGIPFTVDATSQIHCIEDFHR 393
               +CA CS+ +    +    + +H  C  C  C   L G  FT       +C+  F  
Sbjct: 157 KFAPRCARCSKTLTQGGVTYRDQPWHRECLVCTGCQTPLAGQQFT-SRDEDPYCVACFGE 215

Query: 394 KFAPRCSVCGGAIMPEPGQEETVRIVALDRSFHIGCYKCEECGLLLSSEGECQGCYPLDG 453
            FAP+CS C   I+   G +    +   DR +H  C+ C  C   L      QG  P   
Sbjct: 216 LFAPKCSSCKRPIVGLGGGK---YVSFEDRHWHHNCFSCARCSTSLVG----QGFVPDGD 268

Query: 454 HILCKACS 461
            +LC+ CS
Sbjct: 269 QVLCQGCS 276



 Score = 70.5 bits (171), Expect = 3e-12
 Identities = 50/168 (29%), Positives = 68/168 (40%), Gaps = 17/168 (10%)

Query: 305 FVCSTCRAQLRGQHFYAVERRAYCEGCYVATL-EKCATCSQPI--LDRILRAMGKAYHPG 361
           F C+ C   L G+ +   +   YC  CY  T    CA C Q I    R L    + +H G
Sbjct: 5   FDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRHFHEG 64

Query: 362 CFTCVVCHRGLDGIPFTVDATSQIHCIEDFHRKFAPRCSVCGGAIMPEPGQEETVRIVAL 421
           CF C  C R L   PFT    S++ C + +   F+ +CS CG  +MP   + E       
Sbjct: 65  CFRCCRCQRSLADEPFTCQ-DSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYG----- 118

Query: 422 DRSFHIGCYKCEECGLLLSSEG--------ECQGCYPLDGHILCKACS 461
            +++H  C+ C  C   L S           C  CY       C  CS
Sbjct: 119 GQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCS 166


>gi|221316659 leupaxin isoform 1 [Homo sapiens]
          Length = 391

 Score = 82.0 bits (201), Expect = 1e-15
 Identities = 51/185 (27%), Positives = 84/185 (45%), Gaps = 19/185 (10%)

Query: 277 GQCGGCGEDVVGDGAGVVALDRVFHVGCFVCSTCRAQLRGQHFYAVERRAYCEGCYVATL 336
           G C  C + + G    + AL + +H   FVC+ C+ ++    F+     AYC   Y    
Sbjct: 155 GHCASCQKPIAGKV--IHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLF 212

Query: 337 E-KCATCSQPILDRILRAMGKAYHPGCFTCVVCHR--GLDGIPFTVDATSQIHCIEDFHR 393
             +CA C+ PILD++L AM + +HP  F C  C    G +G     +   + +C +DF  
Sbjct: 213 SPRCAYCAAPILDKVLTAMNQTWHPEHFFCSHCGEVFGAEGFH---EKDKKPYCRKDFLA 269

Query: 394 KFAPRCSVCGGAIMPEPGQEETVRIVALDRSFHIGCYKCEECGLLLSSEGECQGCYPLDG 453
            F+P+C  C   ++          + A+D  +H  C+ C +C    S+       + LDG
Sbjct: 270 MFSPKCGGCNRPVLEN-------YLSAMDTVWHPECFVCGDCFTSFST----GSFFELDG 318

Query: 454 HILCK 458
              C+
Sbjct: 319 RPFCE 323



 Score = 73.2 bits (178), Expect = 5e-13
 Identities = 33/113 (29%), Positives = 63/113 (55%), Gaps = 10/113 (8%)

Query: 333 VATLEK--CATCSQPILDRILRAMGKAYHPGCFTCVVCHRGLDGIPFTVDATSQIHCIED 390
           +AT+ K  CA+C +PI  +++ A+G+++HP  F C  C   +   PF  + +   +C  D
Sbjct: 149 IATVPKGHCASCQKPIAGKVIHALGQSWHPEHFVCTHCKEEIGSSPF-FERSGLAYCPND 207

Query: 391 FHRKFAPRCSVCGGAIMPEPGQEETVRIVALDRSFHIGCYKCEECGLLLSSEG 443
           +H+ F+PRC+ C   I+ +        + A+++++H   + C  CG +  +EG
Sbjct: 208 YHQLFSPRCAYCAAPILDKV-------LTAMNQTWHPEHFFCSHCGEVFGAEG 253



 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 47/174 (27%), Positives = 71/174 (40%), Gaps = 33/174 (18%)

Query: 293 VVALDRVFHVGCFVCSTCRAQLRGQHFYAVERRAYCEGCYVATLE-KCATCSQPILDRIL 351
           + A+++ +H   F CS C      + F+  +++ YC   ++A    KC  C++P+L+  L
Sbjct: 228 LTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCGGCNRPVLENYL 287

Query: 352 RAMGKAYHPGCFTCVVCHRG--------LDGIPFTVDATSQIHCIEDFHRKFAPRCSVCG 403
            AM   +HP CF C  C           LDG PF         C   +H +    C  CG
Sbjct: 288 SAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPF---------CELHYHHRRGTLCHGCG 338

Query: 404 GAIMPEPGQEETVRIVALDRSFHIGCYKCEECGLLLS--------SEGECQGCY 449
               P  G+     I A+   FH   + C  C   LS         +  CQ C+
Sbjct: 339 ---QPITGR----CISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPCF 385



 Score = 37.4 bits (85), Expect = 0.030
 Identities = 18/54 (33%), Positives = 26/54 (48%), Gaps = 2/54 (3%)

Query: 279 CGGCGEDVVGDGAGVVALDRVFHVGCFVCSTCRAQLRGQHFYAVERRAYCEGCY 332
           C GCG+ + G    + A+   FH   FVC+ C  QL    F     + YC+ C+
Sbjct: 334 CHGCGQPITG--RCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPCF 385


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.140    0.466 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,692,576
Number of Sequences: 37866
Number of extensions: 2101965
Number of successful extensions: 23548
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 308
Number of HSP's successfully gapped in prelim test: 1402
Number of HSP's that attempted gapping in prelim test: 13705
Number of HSP's gapped (non-prelim): 7487
length of query: 476
length of database: 18,247,518
effective HSP length: 106
effective length of query: 370
effective length of database: 14,233,722
effective search space: 5266477140
effective search space used: 5266477140
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.