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Search of human proteins with 89993690
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|89993690 mouse double minute 2 homolog isoform MDM2a [Homo
sapiens]
(249 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|89993690 mouse double minute 2 homolog isoform MDM2a [Homo sa... 504 e-143
gi|89993689 mouse double minute 2 homolog isoform MDM2 [Homo sap... 351 4e-97
gi|223890201 mouse double minute 2 homolog isoform MDM2g [Homo s... 340 7e-94
gi|89993693 mouse double minute 2 homolog isoform MDM2d [Homo sa... 307 5e-84
gi|223890205 mouse double minute 2 homolog isoform MDM2h [Homo s... 247 8e-66
gi|223890197 mouse double minute 2 homolog isoform MDM2f [Homo s... 237 8e-63
gi|89993691 mouse double minute 2 homolog isoform MDM2e [Homo sa... 204 8e-53
gi|89993692 mouse double minute 2 homolog isoform MDM2b [Homo sa... 178 4e-45
gi|223890207 mouse double minute 2 homolog isoform MDM2i [Homo s... 168 5e-42
gi|88702791 mouse double minute 4 homolog [Homo sapiens] 103 1e-22
gi|223278368 neuralized-like [Homo sapiens] 42 5e-04
gi|217416388 neuralized homolog 1B [Homo sapiens] 39 0.006
gi|58743365 ring finger protein 157 [Homo sapiens] 38 0.007
gi|38788243 myosin regulatory light chain interacting protein [H... 37 0.016
gi|33946285 baculoviral IAP repeat-containing protein 3 [Homo sa... 36 0.027
gi|4502139 baculoviral IAP repeat-containing protein 3 [Homo sap... 36 0.027
gi|214010238 mahogunin, ring finger 1 isoform 4 [Homo sapiens] 36 0.027
gi|214010234 mahogunin, ring finger 1 isoform 2 [Homo sapiens] 36 0.027
gi|11545910 livin inhibitor of apoptosis isoform beta [Homo sapi... 36 0.027
gi|171542821 mitochondrial ubiquitin ligase activator of NFKB 1 ... 36 0.036
gi|37595539 ring finger protein 34 isoform 1 [Homo sapiens] 35 0.061
gi|37595537 ring finger protein 34 isoform 2 [Homo sapiens] 35 0.061
gi|214010236 mahogunin, ring finger 1 isoform 3 [Homo sapiens] 35 0.061
gi|44917608 mahogunin, ring finger 1 isoform 1 [Homo sapiens] 35 0.061
gi|53729363 leucine rich repeat and sterile alpha motif containi... 35 0.061
gi|53729361 leucine rich repeat and sterile alpha motif containi... 35 0.061
gi|53729359 leucine rich repeat and sterile alpha motif containi... 35 0.061
gi|4502141 baculoviral IAP repeat-containing protein 2 [Homo sap... 34 0.10
gi|32528299 baculoviral IAP repeat-containing protein 4 [Homo sa... 34 0.10
gi|30348954 mindbomb homolog 1 [Homo sapiens] 34 0.10
>gi|89993690 mouse double minute 2 homolog isoform MDM2a [Homo
sapiens]
Length = 249
Score = 504 bits (1297), Expect = e-143
Identities = 249/249 (100%), Positives = 249/249 (100%)
Query: 1 MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL 60
MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL
Sbjct: 1 MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL 60
Query: 61 FYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQE 120
FYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQE
Sbjct: 61 FYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQE 120
Query: 121 SSDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEETQDK 180
SSDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEETQDK
Sbjct: 121 SSDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEETQDK 180
Query: 181 EESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQPI 240
EESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQPI
Sbjct: 181 EESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQPI 240
Query: 241 QMIVLTYFP 249
QMIVLTYFP
Sbjct: 241 QMIVLTYFP 249
>gi|89993689 mouse double minute 2 homolog isoform MDM2 [Homo
sapiens]
Length = 497
Score = 351 bits (900), Expect = 4e-97
Identities = 177/180 (98%), Positives = 178/180 (98%)
Query: 1 MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL 60
MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL
Sbjct: 1 MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL 60
Query: 61 FYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQE 120
FYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQE
Sbjct: 61 FYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQE 120
Query: 121 SSDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEETQDK 180
SSDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEE D+
Sbjct: 121 SSDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEENSDE 180
Score = 168 bits (425), Expect = 5e-42
Identities = 85/108 (78%), Positives = 87/108 (80%), Gaps = 7/108 (6%)
Query: 149 QEEKPSSSHLVSRPSTSSRRRAIS-------ETEETQDKEESVESSLPLNAIEPCVICQG 201
Q + S S+PSTSS S E EETQDKEESVESSLPLNAIEPCVICQG
Sbjct: 390 QASQSQESEDYSQPSTSSSIIYSSQEDVKEFEREETQDKEESVESSLPLNAIEPCVICQG 449
Query: 202 RPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQPIQMIVLTYFP 249
RPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQPIQMIVLTYFP
Sbjct: 450 RPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQPIQMIVLTYFP 497
>gi|223890201 mouse double minute 2 homolog isoform MDM2g [Homo
sapiens]
Length = 444
Score = 340 bits (872), Expect = 7e-94
Identities = 171/174 (98%), Positives = 172/174 (98%)
Query: 7 MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQY 66
MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQY
Sbjct: 1 MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQY 60
Query: 67 IMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQESSDSGT 126
IMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQESSDSGT
Sbjct: 61 IMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQESSDSGT 120
Query: 127 SVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEETQDK 180
SVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEE D+
Sbjct: 121 SVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEENSDE 174
Score = 168 bits (425), Expect = 5e-42
Identities = 85/108 (78%), Positives = 87/108 (80%), Gaps = 7/108 (6%)
Query: 149 QEEKPSSSHLVSRPSTSSRRRAIS-------ETEETQDKEESVESSLPLNAIEPCVICQG 201
Q + S S+PSTSS S E EETQDKEESVESSLPLNAIEPCVICQG
Sbjct: 337 QASQSQESEDYSQPSTSSSIIYSSQEDVKEFEREETQDKEESVESSLPLNAIEPCVICQG 396
Query: 202 RPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQPIQMIVLTYFP 249
RPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQPIQMIVLTYFP
Sbjct: 397 RPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQPIQMIVLTYFP 444
>gi|89993693 mouse double minute 2 homolog isoform MDM2d [Homo
sapiens]
Length = 172
Score = 307 bits (787), Expect = 5e-84
Identities = 154/159 (96%), Positives = 155/159 (97%)
Query: 1 MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL 60
MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL
Sbjct: 1 MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL 60
Query: 61 FYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQE 120
FYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQE
Sbjct: 61 FYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQE 120
Query: 121 SSDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLV 159
SSDSGTSVSENRCHLEGGSDQKDLVQELQEEKP + V
Sbjct: 121 SSDSGTSVSENRCHLEGGSDQKDLVQELQEEKPKTKKRV 159
>gi|223890205 mouse double minute 2 homolog isoform MDM2h [Homo
sapiens]
Length = 442
Score = 247 bits (630), Expect = 8e-66
Identities = 132/181 (72%), Positives = 140/181 (77%), Gaps = 8/181 (4%)
Query: 1 MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL 60
MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL
Sbjct: 1 MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL 60
Query: 61 FYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQE 120
FYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQE
Sbjct: 61 FYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQE 120
Query: 121 SSDSGTSVSENRCHLEGGSDQKD--------LVQELQEEKPSSSHLVSRPSTSSRRRAIS 172
+ S R + S +++E+ E+ SSS PS +S
Sbjct: 121 ENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVS 180
Query: 173 E 173
E
Sbjct: 181 E 181
Score = 168 bits (425), Expect = 5e-42
Identities = 85/108 (78%), Positives = 87/108 (80%), Gaps = 7/108 (6%)
Query: 149 QEEKPSSSHLVSRPSTSSRRRAIS-------ETEETQDKEESVESSLPLNAIEPCVICQG 201
Q + S S+PSTSS S E EETQDKEESVESSLPLNAIEPCVICQG
Sbjct: 335 QASQSQESEDYSQPSTSSSIIYSSQEDVKEFEREETQDKEESVESSLPLNAIEPCVICQG 394
Query: 202 RPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQPIQMIVLTYFP 249
RPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQPIQMIVLTYFP
Sbjct: 395 RPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQPIQMIVLTYFP 442
>gi|223890197 mouse double minute 2 homolog isoform MDM2f [Homo
sapiens]
Length = 452
Score = 237 bits (604), Expect = 8e-63
Identities = 132/180 (73%), Positives = 133/180 (73%), Gaps = 45/180 (25%)
Query: 1 MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL 60
MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKE
Sbjct: 1 MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKE-- 58
Query: 61 FYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQE 120
KIYTMIYRNLVVVNQQE
Sbjct: 59 -------------------------------------------KIYTMIYRNLVVVNQQE 75
Query: 121 SSDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEETQDK 180
SSDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEE D+
Sbjct: 76 SSDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEENSDE 135
Score = 168 bits (425), Expect = 5e-42
Identities = 85/108 (78%), Positives = 87/108 (80%), Gaps = 7/108 (6%)
Query: 149 QEEKPSSSHLVSRPSTSSRRRAIS-------ETEETQDKEESVESSLPLNAIEPCVICQG 201
Q + S S+PSTSS S E EETQDKEESVESSLPLNAIEPCVICQG
Sbjct: 345 QASQSQESEDYSQPSTSSSIIYSSQEDVKEFEREETQDKEESVESSLPLNAIEPCVICQG 404
Query: 202 RPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQPIQMIVLTYFP 249
RPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQPIQMIVLTYFP
Sbjct: 405 RPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQPIQMIVLTYFP 452
>gi|89993691 mouse double minute 2 homolog isoform MDM2e [Homo
sapiens]
Length = 179
Score = 204 bits (518), Expect = 8e-53
Identities = 101/104 (97%), Positives = 102/104 (98%)
Query: 1 MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL 60
MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL
Sbjct: 1 MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL 60
Query: 61 FYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRK 104
FYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKE +
Sbjct: 61 FYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEFER 104
Score = 165 bits (418), Expect = 3e-41
Identities = 76/77 (98%), Positives = 76/77 (98%)
Query: 173 ETEETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKP 232
E EETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKP
Sbjct: 103 EREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKP 162
Query: 233 CPVCRQPIQMIVLTYFP 249
CPVCRQPIQMIVLTYFP
Sbjct: 163 CPVCRQPIQMIVLTYFP 179
>gi|89993692 mouse double minute 2 homolog isoform MDM2b [Homo
sapiens]
Length = 111
Score = 178 bits (451), Expect = 4e-45
Identities = 90/101 (89%), Positives = 94/101 (93%), Gaps = 1/101 (0%)
Query: 1 MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL 60
MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL
Sbjct: 1 MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL 60
Query: 61 FYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKE 101
FYLGQYIMTKRLYDEKQQHIVYCSND +LF + S++E
Sbjct: 61 FYLGQYIMTKRLYDEKQQHIVYCSND-CANLFPLVDLSIRE 100
>gi|223890207 mouse double minute 2 homolog isoform MDM2i [Homo
sapiens]
Length = 295
Score = 168 bits (425), Expect = 5e-42
Identities = 85/108 (78%), Positives = 87/108 (80%), Gaps = 7/108 (6%)
Query: 149 QEEKPSSSHLVSRPSTSSRRRAIS-------ETEETQDKEESVESSLPLNAIEPCVICQG 201
Q + S S+PSTSS S E EETQDKEESVESSLPLNAIEPCVICQG
Sbjct: 188 QASQSQESEDYSQPSTSSSIIYSSQEDVKEFEREETQDKEESVESSLPLNAIEPCVICQG 247
Query: 202 RPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQPIQMIVLTYFP 249
RPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQPIQMIVLTYFP
Sbjct: 248 RPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQPIQMIVLTYFP 295
Score = 105 bits (263), Expect = 3e-23
Identities = 53/54 (98%), Positives = 53/54 (98%)
Query: 7 MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL 60
MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKE L
Sbjct: 1 MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEDL 54
>gi|88702791 mouse double minute 4 homolog [Homo sapiens]
Length = 490
Score = 103 bits (258), Expect = 1e-22
Identities = 54/121 (44%), Positives = 79/121 (65%), Gaps = 1/121 (0%)
Query: 34 VRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFG 93
VRPK LLK+L + GAQ + +T+KEV+ YLGQYIM K+LYD+++QH+VYC DLLG+L G
Sbjct: 27 VRPKLPLLKILHAAGAQGEMFTVKEVMHYLGQYIMVKQLYDQQEQHMVYCGGDLLGELLG 86
Query: 94 VPSFSVKEHRKIYTMIYRNLVVVNQQESSDSGTSVSENRCHLEGGSDQKDLVQELQEEKP 153
SFSVK+ +Y M+ +NLV + ++D+ +++ + H Q L Q +E
Sbjct: 87 RQSFSVKDPSPLYDMLRKNLVTL-ATATTDAAQTLALAQDHSMDIPSQDQLKQSAEESST 145
Query: 154 S 154
S
Sbjct: 146 S 146
Score = 79.3 bits (194), Expect = 3e-15
Identities = 32/88 (36%), Positives = 56/88 (63%), Gaps = 2/88 (2%)
Query: 160 SRPSTSSRRRAISETEETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMAC 219
S+ + SS + E + E++E N ++PC +C+ RP++G I+HG+TGHL+ C
Sbjct: 403 SQETISSMGEQLDNLSEQRTDTENMEDCQ--NLLKPCSLCEKRPRDGNIIHGRTGHLVTC 460
Query: 220 FTCAKKLKKRNKPCPVCRQPIQMIVLTY 247
F CA++LKK CP+C++ IQ+++ +
Sbjct: 461 FHCARRLKKAGASCPICKKEIQLVIKVF 488
>gi|223278368 neuralized-like [Homo sapiens]
Length = 574
Score = 42.0 bits (97), Expect = 5e-04
Identities = 24/70 (34%), Positives = 35/70 (50%), Gaps = 11/70 (15%)
Query: 187 SLPLNAIEP--------CVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKR-NKPCPVCR 237
SLP + + P C IC + I GH+ C+ C +LKK + CP+CR
Sbjct: 504 SLPESPVTPGLGQWSDECTICYEHAVDTVIY--TCGHMCLCYACGLRLKKALHACCPICR 561
Query: 238 QPIQMIVLTY 247
+PI+ I+ TY
Sbjct: 562 RPIKDIIKTY 571
>gi|217416388 neuralized homolog 1B [Homo sapiens]
Length = 555
Score = 38.5 bits (88), Expect = 0.006
Identities = 14/37 (37%), Positives = 25/37 (67%), Gaps = 1/37 (2%)
Query: 214 GHLMACFTCAKKLKKRNKPC-PVCRQPIQMIVLTYFP 249
GH+ C +C +LK++ + C P+CR+PI+ ++ Y P
Sbjct: 519 GHMCLCHSCGLRLKRQARACCPICRRPIKDVIKIYRP 555
>gi|58743365 ring finger protein 157 [Homo sapiens]
Length = 679
Score = 38.1 bits (87), Expect = 0.007
Identities = 23/74 (31%), Positives = 38/74 (51%), Gaps = 4/74 (5%)
Query: 171 ISETEETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRN 230
I TQD + + E + N+ E CV+C ++ I+ + HL C TCA L+ +
Sbjct: 254 IENKYNTQDSKVA-EDEVSDNSAE-CVVCLSDVRDTLILPCR--HLCLCNTCADTLRYQA 309
Query: 231 KPCPVCRQPIQMIV 244
CP+CR P + ++
Sbjct: 310 NNCPICRLPFRALL 323
>gi|38788243 myosin regulatory light chain interacting protein [Homo
sapiens]
Length = 445
Score = 37.0 bits (84), Expect = 0.016
Identities = 27/106 (25%), Positives = 40/106 (37%), Gaps = 6/106 (5%)
Query: 144 LVQELQEEKPSSSHLVSRPSTSSRRRAISETEETQDKEESVESSLPLNAIEPCVICQGRP 203
+V + S SH + S SS + E Q E L C++C
Sbjct: 335 VVDLVSRNNQSPSHSPLKSSESSMNCSSCEGLSCQQTRVLQEKLRKLKEAMLCMVCCEEE 394
Query: 204 KNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQPIQMIVLTYFP 249
N GH + C +CA +L+ CPVCR ++ + Y P
Sbjct: 395 INSTFC--PCGHTVCCESCAAQLQS----CPVCRSRVEHVQHVYLP 434
>gi|33946285 baculoviral IAP repeat-containing protein 3 [Homo
sapiens]
Length = 604
Score = 36.2 bits (82), Expect = 0.027
Identities = 20/52 (38%), Positives = 26/52 (50%), Gaps = 6/52 (11%)
Query: 196 CVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQPIQMIVLTY 247
C +C K IV GHL+ C CA L+K CP+CR I+ V T+
Sbjct: 557 CKVCMD--KEVSIVFIPCGHLVVCKDCAPSLRK----CPICRSTIKGTVRTF 602
>gi|4502139 baculoviral IAP repeat-containing protein 3 [Homo
sapiens]
Length = 604
Score = 36.2 bits (82), Expect = 0.027
Identities = 20/52 (38%), Positives = 26/52 (50%), Gaps = 6/52 (11%)
Query: 196 CVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQPIQMIVLTY 247
C +C K IV GHL+ C CA L+K CP+CR I+ V T+
Sbjct: 557 CKVCMD--KEVSIVFIPCGHLVVCKDCAPSLRK----CPICRSTIKGTVRTF 602
>gi|214010238 mahogunin, ring finger 1 isoform 4 [Homo sapiens]
Length = 531
Score = 36.2 bits (82), Expect = 0.027
Identities = 36/159 (22%), Positives = 69/159 (43%), Gaps = 10/159 (6%)
Query: 92 FGVPSFSVK----EHRKIYTMIYRNLVVVNQQESSDSGTSVSE--NRCHLEGGSDQKDLV 145
F +PSF + + ++ + R + V Q D G +V E H+ + +K +
Sbjct: 171 FSLPSFKIDFSEWKDDELNFDLDRGVFPVVIQAVVDEGDAVVEVTGHAHVLLAAFEKHMD 230
Query: 146 QELQEEKPSSSHLVSRPSTSSRRRAISETEETQDKEESVESSLPLNAIEPCVICQGRPKN 205
+ +V R S + E + Q+ + S + + N+ E CV+C ++
Sbjct: 231 GSFSVKPLKQKQIVDRVSYLLQEIYGIENKNNQETKPSDDENSD-NSNE-CVVCLSDLRD 288
Query: 206 GCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQPIQMIV 244
I+ + HL C +CA L+ + CP+CR P + ++
Sbjct: 289 TLILPCR--HLCLCTSCADTLRYQANNCPICRLPFRALL 325
>gi|214010234 mahogunin, ring finger 1 isoform 2 [Homo sapiens]
Length = 555
Score = 36.2 bits (82), Expect = 0.027
Identities = 36/159 (22%), Positives = 69/159 (43%), Gaps = 10/159 (6%)
Query: 92 FGVPSFSVK----EHRKIYTMIYRNLVVVNQQESSDSGTSVSE--NRCHLEGGSDQKDLV 145
F +PSF + + ++ + R + V Q D G +V E H+ + +K +
Sbjct: 171 FSLPSFKIDFSEWKDDELNFDLDRGVFPVVIQAVVDEGDAVVEVTGHAHVLLAAFEKHMD 230
Query: 146 QELQEEKPSSSHLVSRPSTSSRRRAISETEETQDKEESVESSLPLNAIEPCVICQGRPKN 205
+ +V R S + E + Q+ + S + + N+ E CV+C ++
Sbjct: 231 GSFSVKPLKQKQIVDRVSYLLQEIYGIENKNNQETKPSDDENSD-NSNE-CVVCLSDLRD 288
Query: 206 GCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQPIQMIV 244
I+ + HL C +CA L+ + CP+CR P + ++
Sbjct: 289 TLILPCR--HLCLCTSCADTLRYQANNCPICRLPFRALL 325
>gi|11545910 livin inhibitor of apoptosis isoform beta [Homo
sapiens]
Length = 280
Score = 36.2 bits (82), Expect = 0.027
Identities = 34/122 (27%), Positives = 49/122 (40%), Gaps = 9/122 (7%)
Query: 127 SVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEETQDKEESVES 186
SV E L G D + ++ PS P + RR + + VE+
Sbjct: 165 SVQETHSQLLGSWDPWEEPEDAAPVAPSVP-ASGYPELPTPRREVQSESAQEPGARDVEA 223
Query: 187 SLP-LNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQPIQMIVL 245
L L C +C R + IV GHL+ C CA L+ CP+CR P++ V
Sbjct: 224 QLRRLQEERTCKVCLDRAVS--IVFVPCGHLV-CAECAPGLQL----CPICRAPVRSRVR 276
Query: 246 TY 247
T+
Sbjct: 277 TF 278
>gi|171542821 mitochondrial ubiquitin ligase activator of NFKB 1
[Homo sapiens]
Length = 352
Score = 35.8 bits (81), Expect = 0.036
Identities = 18/52 (34%), Positives = 28/52 (53%), Gaps = 3/52 (5%)
Query: 196 CVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQPIQMIVLTY 247
CV+C K+ V + GH+ +C C + L + K CP+CRQ I ++ Y
Sbjct: 302 CVVCLSSFKS--CVFLECGHVCSCTECYRALPEPKK-CPICRQAITRVIPLY 350
>gi|37595539 ring finger protein 34 isoform 1 [Homo sapiens]
Length = 373
Score = 35.0 bits (79), Expect = 0.061
Identities = 17/71 (23%), Positives = 35/71 (49%), Gaps = 16/71 (22%)
Query: 168 RRAISETEETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLK 227
+++ E + QD+E+ + ++A+ CV+ + GH++ C C K++
Sbjct: 308 QKSYGERLQLQDEEDDSLCRICMDAVIDCVLLE------------CGHMVTCTKCGKRMS 355
Query: 228 KRNKPCPVCRQ 238
+ CP+CRQ
Sbjct: 356 E----CPICRQ 362
>gi|37595537 ring finger protein 34 isoform 2 [Homo sapiens]
Length = 372
Score = 35.0 bits (79), Expect = 0.061
Identities = 17/71 (23%), Positives = 35/71 (49%), Gaps = 16/71 (22%)
Query: 168 RRAISETEETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLK 227
+++ E + QD+E+ + ++A+ CV+ + GH++ C C K++
Sbjct: 307 QKSYGERLQLQDEEDDSLCRICMDAVIDCVLLE------------CGHMVTCTKCGKRMS 354
Query: 228 KRNKPCPVCRQ 238
+ CP+CRQ
Sbjct: 355 E----CPICRQ 361
>gi|214010236 mahogunin, ring finger 1 isoform 3 [Homo sapiens]
Length = 552
Score = 35.0 bits (79), Expect = 0.061
Identities = 28/111 (25%), Positives = 51/111 (45%), Gaps = 13/111 (11%)
Query: 134 HLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEETQDKEESVESSLPLNAI 193
H++G K L Q+ +V R S + E + Q+ + S + + N+
Sbjct: 227 HMDGSFSVKPLKQK---------QIVDRVSYLLQEIYGIENKNNQETKPSDDENSD-NSN 276
Query: 194 EPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQPIQMIV 244
E CV+C ++ I+ + HL C +CA L+ + CP+CR P + ++
Sbjct: 277 E-CVVCLSDLRDTLILPCR--HLCLCTSCADTLRYQANNCPICRLPFRALL 324
>gi|44917608 mahogunin, ring finger 1 isoform 1 [Homo sapiens]
Length = 576
Score = 35.0 bits (79), Expect = 0.061
Identities = 28/111 (25%), Positives = 51/111 (45%), Gaps = 13/111 (11%)
Query: 134 HLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEETQDKEESVESSLPLNAI 193
H++G K L Q+ +V R S + E + Q+ + S + + N+
Sbjct: 227 HMDGSFSVKPLKQK---------QIVDRVSYLLQEIYGIENKNNQETKPSDDENSD-NSN 276
Query: 194 EPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQPIQMIV 244
E CV+C ++ I+ + HL C +CA L+ + CP+CR P + ++
Sbjct: 277 E-CVVCLSDLRDTLILPCR--HLCLCTSCADTLRYQANNCPICRLPFRALL 324
>gi|53729363 leucine rich repeat and sterile alpha motif containing
1 [Homo sapiens]
Length = 723
Score = 35.0 bits (79), Expect = 0.061
Identities = 23/74 (31%), Positives = 33/74 (44%), Gaps = 10/74 (13%)
Query: 178 QDKEESVESSLPLNAIE----PCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKPC 233
Q+ ESV S P +E CV+C R ++ GH+ C C + L+ C
Sbjct: 653 QEPPESVRPSAPPAELEVQASECVVCLEREAQ--MIFLNCGHVCCCQQCCQPLRT----C 706
Query: 234 PVCRQPIQMIVLTY 247
P+CRQ I + Y
Sbjct: 707 PLCRQDIAQRLRIY 720
>gi|53729361 leucine rich repeat and sterile alpha motif containing
1 [Homo sapiens]
Length = 723
Score = 35.0 bits (79), Expect = 0.061
Identities = 23/74 (31%), Positives = 33/74 (44%), Gaps = 10/74 (13%)
Query: 178 QDKEESVESSLPLNAIE----PCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKPC 233
Q+ ESV S P +E CV+C R ++ GH+ C C + L+ C
Sbjct: 653 QEPPESVRPSAPPAELEVQASECVVCLEREAQ--MIFLNCGHVCCCQQCCQPLRT----C 706
Query: 234 PVCRQPIQMIVLTY 247
P+CRQ I + Y
Sbjct: 707 PLCRQDIAQRLRIY 720
>gi|53729359 leucine rich repeat and sterile alpha motif containing
1 [Homo sapiens]
Length = 723
Score = 35.0 bits (79), Expect = 0.061
Identities = 23/74 (31%), Positives = 33/74 (44%), Gaps = 10/74 (13%)
Query: 178 QDKEESVESSLPLNAIE----PCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKPC 233
Q+ ESV S P +E CV+C R ++ GH+ C C + L+ C
Sbjct: 653 QEPPESVRPSAPPAELEVQASECVVCLEREAQ--MIFLNCGHVCCCQQCCQPLRT----C 706
Query: 234 PVCRQPIQMIVLTY 247
P+CRQ I + Y
Sbjct: 707 PLCRQDIAQRLRIY 720
>gi|4502141 baculoviral IAP repeat-containing protein 2 [Homo
sapiens]
Length = 618
Score = 34.3 bits (77), Expect = 0.10
Identities = 19/52 (36%), Positives = 26/52 (50%), Gaps = 6/52 (11%)
Query: 196 CVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQPIQMIVLTY 247
C +C K +V GHL+ C CA L+K CP+CR I+ V T+
Sbjct: 571 CKVCMD--KEVSVVFIPCGHLVVCQECAPSLRK----CPICRGIIKGTVRTF 616
>gi|32528299 baculoviral IAP repeat-containing protein 4 [Homo
sapiens]
Length = 497
Score = 34.3 bits (77), Expect = 0.10
Identities = 40/142 (28%), Positives = 63/142 (44%), Gaps = 29/142 (20%)
Query: 103 RKIYTMIYRNLVVVNQQESSDSGTSVSENRCHLE-----GGSDQKDL---VQELQEEKPS 154
R+I I++N +V QE+ G S + + +E GS+ K L V +L +
Sbjct: 364 RRIDDTIFQNPMV---QEAIRMGFSFKDIKKIMEEKIQISGSNYKSLEVLVADLVNAQKD 420
Query: 155 SSHLVSRPSTSSRRRAISETEETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTG 214
S + S +S ++ IS E+ + +E + C IC R N IV G
Sbjct: 421 S--MQDESSQTSLQKEISTEEQLRRLQEE----------KLCKICMDR--NIAIVFVPCG 466
Query: 215 HLMACFTCAKKLKKRNKPCPVC 236
HL+ C CA+ + K CP+C
Sbjct: 467 HLVTCKQCAEAVDK----CPMC 484
>gi|30348954 mindbomb homolog 1 [Homo sapiens]
Length = 1006
Score = 34.3 bits (77), Expect = 0.10
Identities = 17/49 (34%), Positives = 24/49 (48%), Gaps = 6/49 (12%)
Query: 193 IEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQPIQ 241
IE CV+C K ++ GH+ AC CA +KK C CR ++
Sbjct: 863 IEECVVCSD--KKAAVLFQPCGHMCACENCANLMKK----CVQCRAVVE 905
Score = 33.5 bits (75), Expect = 0.18
Identities = 13/49 (26%), Positives = 27/49 (55%), Gaps = 6/49 (12%)
Query: 193 IEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQPIQ 241
+E C++C ++ + G GH+ C C+ ++KK C +C++ +Q
Sbjct: 816 LEECMVCSDMKRD--TLFGPCGHIATCSLCSPRVKK----CLICKEQVQ 858
Score = 28.5 bits (62), Expect = 5.7
Identities = 15/52 (28%), Positives = 24/52 (46%), Gaps = 8/52 (15%)
Query: 196 CVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQPIQMIVLTY 247
C +C R KN + G C C ++ + CP+CR+ I+ +L Y
Sbjct: 963 CPVCLDRLKNMIFLCGHG----TCQLCGDRMSE----CPICRKAIERRILLY 1006
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.131 0.378
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,662,761
Number of Sequences: 37866
Number of extensions: 438510
Number of successful extensions: 2176
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 39
Number of HSP's successfully gapped in prelim test: 101
Number of HSP's that attempted gapping in prelim test: 2044
Number of HSP's gapped (non-prelim): 217
length of query: 249
length of database: 18,247,518
effective HSP length: 100
effective length of query: 149
effective length of database: 14,460,918
effective search space: 2154676782
effective search space used: 2154676782
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.