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Search of human proteins with 14150064
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|14150064 polymerase (RNA) III (DNA directed) polypeptide G
(32kD) like [Homo sapiens]
(218 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|14150064 polymerase (RNA) III (DNA directed) polypeptide G (3... 447 e-126
gi|115529475 polymerase (RNA) III (DNA directed) polypeptide G (... 206 2e-53
gi|58761548 tau tubulin kinase 1 [Homo sapiens] 64 1e-10
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)... 60 2e-09
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] 59 2e-09
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] 59 2e-09
gi|17975763 myelin transcription factor 1 [Homo sapiens] 59 4e-09
gi|118600967 shroom family member 4 [Homo sapiens] 56 3e-08
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 56 3e-08
gi|239757046 PREDICTED: similar to hCG1790759 [Homo sapiens] 55 5e-08
gi|239751558 PREDICTED: similar to hCG1790759 [Homo sapiens] 55 5e-08
gi|169212818 PREDICTED: similar to hCG1790759 [Homo sapiens] 55 5e-08
gi|169210053 PREDICTED: hypothetical protein [Homo sapiens] 55 6e-08
gi|110349719 titin isoform N2-A [Homo sapiens] 53 2e-07
gi|239745093 PREDICTED: hypothetical protein XP_002343359 [Homo ... 53 2e-07
gi|4757900 calreticulin precursor [Homo sapiens] 53 2e-07
gi|221219020 NYD-SP11 protein [Homo sapiens] 52 3e-07
gi|4506411 Ran GTPase activating protein 1 [Homo sapiens] 52 4e-07
gi|157694494 MYB binding protein 1a isoform 1 [Homo sapiens] 52 5e-07
gi|157694492 MYB binding protein 1a isoform 2 [Homo sapiens] 52 5e-07
gi|46276863 parathymosin [Homo sapiens] 52 5e-07
gi|211904182 DDB1 and CUL4 associated factor 8-like 2 [Homo sapi... 51 7e-07
gi|154759293 cysteine-rich hydrophobic domain 1 [Homo sapiens] 51 7e-07
gi|169202818 PREDICTED: similar to hCG1991922 [Homo sapiens] 51 9e-07
gi|60498973 myelin transcription factor 1-like [Homo sapiens] 51 9e-07
gi|22749303 hypothetical protein LOC196477 [Homo sapiens] 51 9e-07
gi|21735569 claspin [Homo sapiens] 50 1e-06
gi|156142199 euchromatic histone-lysine N-methyltransferase 2 is... 50 1e-06
gi|156142197 euchromatic histone-lysine N-methyltransferase 2 is... 50 1e-06
gi|87298939 hypothetical protein LOC131831 [Homo sapiens] 50 1e-06
>gi|14150064 polymerase (RNA) III (DNA directed) polypeptide G
(32kD) like [Homo sapiens]
Length = 218
Score = 447 bits (1151), Expect = e-126
Identities = 218/218 (100%), Positives = 218/218 (100%)
Query: 1 MASRGGGRGRGRGQLTFNVEAVGIGKGDALPPPTLQPSPLFPPLEFRPVPLPSGEEGEYV 60
MASRGGGRGRGRGQLTFNVEAVGIGKGDALPPPTLQPSPLFPPLEFRPVPLPSGEEGEYV
Sbjct: 1 MASRGGGRGRGRGQLTFNVEAVGIGKGDALPPPTLQPSPLFPPLEFRPVPLPSGEEGEYV 60
Query: 61 LALKQELRGAMRQLPYFIRPAVPKRDVERYSDKYQMSGPIDNAIDWNPDWRRLPRELKIR 120
LALKQELRGAMRQLPYFIRPAVPKRDVERYSDKYQMSGPIDNAIDWNPDWRRLPRELKIR
Sbjct: 61 LALKQELRGAMRQLPYFIRPAVPKRDVERYSDKYQMSGPIDNAIDWNPDWRRLPRELKIR 120
Query: 121 VRKLQKERITILLPKRPPKTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEE 180
VRKLQKERITILLPKRPPKTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEE
Sbjct: 121 VRKLQKERITILLPKRPPKTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEE 180
Query: 181 EEYDEEEHEEETDYIMSYFDNGEDFGGDSDDNMDEAIY 218
EEYDEEEHEEETDYIMSYFDNGEDFGGDSDDNMDEAIY
Sbjct: 181 EEYDEEEHEEETDYIMSYFDNGEDFGGDSDDNMDEAIY 218
>gi|115529475 polymerase (RNA) III (DNA directed) polypeptide G
(32kD) [Homo sapiens]
Length = 223
Score = 206 bits (523), Expect = 2e-53
Identities = 112/226 (49%), Positives = 146/226 (64%), Gaps = 18/226 (7%)
Query: 6 GGRGRGRGQLTFNVEAVGIGKGDALPPPTLQPSPLFPPLEFRPVPLPSGEEGEYVLALKQ 65
G +GRGR TFN+EAVG KG+ LP L+P PLFP +++PVPL +GE EY+LALKQ
Sbjct: 3 GNKGRGRAAYTFNIEAVGFSKGEKLPDVVLKPPPLFPDTDYKPVPLKTGEGEEYMLALKQ 62
Query: 66 ELRGAMRQLPYFIRPAVPKRDVERYSDKYQMSGPIDNAIDWNPDWRRLPRELKIRVRKLQ 125
ELR M+++PYFI ++D+ERYS +Y +W PDWRRLPRE+ R K +
Sbjct: 63 ELRETMKRMPYFIETPEERQDIERYSKRYMKV----YKEEWIPDWRRLPREMMPR-NKCK 117
Query: 126 KERITILLPKRPPKTT--EDKEETIQKLETLEKK-EEEVTSEEDEEKEEEEEKEEE---- 178
K K K T + E+ ++K+E LEK+ + E + EE+EEKE +EK +E
Sbjct: 118 KAGPKPKKAKDAGKGTPLTNTEDVLKKMEELEKRGDGEKSDEENEEKEGSKEKSKEGDDD 177
Query: 179 ------EEEEYDEEEHEEETDYIMSYFDNGEDFGGDSDDNMDEAIY 218
E+EEYDEEE EEE DYI SYF++G+DFG DSDDNMDEA Y
Sbjct: 178 DDDDAAEQEEYDEEEQEEENDYINSYFEDGDDFGADSDDNMDEATY 223
>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
Length = 1321
Score = 63.5 bits (153), Expect = 1e-10
Identities = 53/177 (29%), Positives = 80/177 (45%), Gaps = 37/177 (20%)
Query: 23 GIGKGDALPPPTLQPSPLFPPLEFRPVPL-----PSGEEGE-YVLALKQELRGAMRQLPY 76
G G+ + PPT SP PL P P P+G + + + +A E+ G R +P
Sbjct: 623 GDGRSETSQPPT-PGSPSHSPLHSGPRPRRRESDPTGPQRQVFSVAPPFEVNGLPRAVPL 681
Query: 77 FIRPAVPKRDVERYSDKYQMSGPIDNAIDWNPDWRRLPRELKIRVRKLQKERITILLPKR 136
+ KRD+ Y ++ ++ RVR++ + + P+
Sbjct: 682 SLPYQDFKRDLSDYRERARLLN---------------------RVRRVGFSHMLLTTPQV 720
Query: 137 PPKTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEEETD 193
P + + KEEE EEDEE+EEE+E+EEEEEEE +EEE EEE +
Sbjct: 721 PLAPVQPQANG---------KEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEE 768
>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
[Homo sapiens]
Length = 2073
Score = 59.7 bits (143), Expect = 2e-09
Identities = 35/75 (46%), Positives = 46/75 (61%), Gaps = 4/75 (5%)
Query: 123 KLQKERITILLPKRPPKTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEE 182
K+Q + + P+ P T E Q LE ++ EE EEDEE+EEEEE+EEE+EEE
Sbjct: 1038 KVQSKNKYLHSPESRPVTGERG----QLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEE 1093
Query: 183 YDEEEHEEETDYIMS 197
+EEE EEE + I S
Sbjct: 1094 EEEEEEEEEEENIQS 1108
Score = 52.4 bits (124), Expect = 3e-07
Identities = 29/69 (42%), Positives = 40/69 (57%)
Query: 119 IRVRKLQKERITILLPKRPPKTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEE 178
IR+ + KE LLP+ + E EK E+++ E+EE+EEEEE+EEE
Sbjct: 1305 IRIEEEVKETGEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEE 1364
Query: 179 EEEEYDEEE 187
EEEE +EEE
Sbjct: 1365 EEEEGEEEE 1373
Score = 38.9 bits (89), Expect = 0.003
Identities = 27/86 (31%), Positives = 44/86 (51%), Gaps = 12/86 (13%)
Query: 136 RPPKTTEDKEETIQKLETLEKKEEE----VTSEEDEEKEEEEEK-----EEEEEEEYDEE 186
+P + E++EE ++ E E +EEE V + D K +E+E+ E+E+ D+
Sbjct: 1349 KPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDH 1408
Query: 187 EHEEETDYIMSYFDNGEDFGGDSDDN 212
E EEE D S+ ED D +D+
Sbjct: 1409 EEEEEEDEEPSH---NEDHDADDEDD 1431
Score = 38.5 bits (88), Expect = 0.004
Identities = 20/59 (33%), Positives = 32/59 (54%)
Query: 135 KRPPKTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEEETD 193
++ P + K + + E+ E E ++ EEE+EEE+EEE +EEE EEE +
Sbjct: 1033 RQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDE 1091
Score = 37.0 bits (84), Expect = 0.013
Identities = 20/53 (37%), Positives = 32/53 (60%)
Query: 122 RKLQKERITILLPKRPPKTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEE 174
R + ER +L + E++EE ++ E E++EE+ EE+EE+EEEEE
Sbjct: 1052 RPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEE 1104
Score = 36.2 bits (82), Expect = 0.022
Identities = 18/50 (36%), Positives = 31/50 (62%), Gaps = 1/50 (2%)
Query: 155 EKKEEEVTSE-EDEEKEEEEEKEEEEEEEYDEEEHEEETDYIMSYFDNGE 203
EK+E E+++E ED + ++ E+EEEE+EE E + D S+ ++ E
Sbjct: 1389 EKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAE 1438
Score = 32.0 bits (71), Expect = 0.42
Identities = 13/58 (22%), Positives = 31/58 (53%)
Query: 135 KRPPKTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEEET 192
++ P + +E+ ++ T ++ + E+EE+E+EE E+ + DE++ E+
Sbjct: 1379 EKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMES 1436
Score = 31.6 bits (70), Expect = 0.55
Identities = 19/72 (26%), Positives = 38/72 (52%), Gaps = 6/72 (8%)
Query: 135 KRPPKTTEDKEET--IQKLETLEKKEEEVTSEEDEEKEEEE----EKEEEEEEEYDEEEH 188
K P+ + +KE++ + E E+++EE + ED + ++E+ E E E+EE E
Sbjct: 1390 KEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVEKEELPRESF 1449
Query: 189 EEETDYIMSYFD 200
+E + ++ D
Sbjct: 1450 KEVLENQETFLD 1461
Score = 30.8 bits (68), Expect = 0.93
Identities = 24/90 (26%), Positives = 37/90 (41%)
Query: 125 QKERITILLPKRPPKTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYD 184
QKE P + E+ +ET + L E+ E T EK E++ + +
Sbjct: 1292 QKETSEGKTSPSPIRIEEEVKETGEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPE 1351
Query: 185 EEEHEEETDYIMSYFDNGEDFGGDSDDNMD 214
EEE EEE + + GE+ G + D
Sbjct: 1352 EEEEEEEEEEEEEEEEEGEEEEGGGNVEKD 1381
Score = 30.0 bits (66), Expect = 1.6
Identities = 21/70 (30%), Positives = 30/70 (42%), Gaps = 2/70 (2%)
Query: 125 QKERITILLPKRPPKTTEDKEETIQKLETLEKKEEEVTSEEDEEKEE--EEEKEEEEEEE 182
+KE I K +D EE ++ E E+ +ED+ E E EKEE E
Sbjct: 1389 EKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVEKEELPRES 1448
Query: 183 YDEEEHEEET 192
+ E +ET
Sbjct: 1449 FKEVLENQET 1458
>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
Length = 709
Score = 59.3 bits (142), Expect = 2e-09
Identities = 34/76 (44%), Positives = 49/76 (64%), Gaps = 3/76 (3%)
Query: 141 TEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEEETDYIMSYFD 200
TE++EE +++ + E +E E +EEDEE +E+ E+EEEEEEE +EEE EEE +Y D
Sbjct: 198 TENEEEGVEE-DVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERD 256
Query: 201 NGEDFGGDSDDNMDEA 216
E+ G+ D EA
Sbjct: 257 QKEE--GNDYDTRSEA 270
Score = 44.3 bits (103), Expect = 8e-05
Identities = 23/74 (31%), Positives = 38/74 (51%)
Query: 142 EDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEEETDYIMSYFDN 201
E+ +E ++ E E++EEE EE+EE E++E ++EE +YD ++ F +
Sbjct: 223 EEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTD 282
Query: 202 GEDFGGDSDDNMDE 215
G G D DE
Sbjct: 283 GSVRSGSGTDGSDE 296
Score = 38.5 bits (88), Expect = 0.004
Identities = 23/71 (32%), Positives = 37/71 (52%), Gaps = 2/71 (2%)
Query: 145 EETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEEETDYIMSYFDNGED 204
+E E E+ EE E++E +E+ EE EE +E+ +EEE EEE + + E+
Sbjct: 192 DEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEE--EEEEEEEEE 249
Query: 205 FGGDSDDNMDE 215
+ D D +E
Sbjct: 250 YEQDERDQKEE 260
Score = 36.6 bits (83), Expect = 0.017
Identities = 22/90 (24%), Positives = 45/90 (50%), Gaps = 1/90 (1%)
Query: 127 ERITILLPKRPPKTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDE- 185
ERI + + +R ++++ +E + E E + DE+ E +EE EE+ +E
Sbjct: 153 ERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEED 212
Query: 186 EEHEEETDYIMSYFDNGEDFGGDSDDNMDE 215
EE EE+ + ++GE+ + ++ +E
Sbjct: 213 EEVEEDAEEDEEVDEDGEEEEEEEEEEEEE 242
>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
Length = 727
Score = 59.3 bits (142), Expect = 2e-09
Identities = 34/76 (44%), Positives = 49/76 (64%), Gaps = 3/76 (3%)
Query: 141 TEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEEETDYIMSYFD 200
TE++EE +++ + E +E E +EEDEE +E+ E+EEEEEEE +EEE EEE +Y D
Sbjct: 198 TENEEEGVEE-DVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERD 256
Query: 201 NGEDFGGDSDDNMDEA 216
E+ G+ D EA
Sbjct: 257 QKEE--GNDYDTRSEA 270
Score = 44.3 bits (103), Expect = 8e-05
Identities = 23/74 (31%), Positives = 38/74 (51%)
Query: 142 EDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEEETDYIMSYFDN 201
E+ +E ++ E E++EEE EE+EE E++E ++EE +YD ++ F +
Sbjct: 223 EEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTD 282
Query: 202 GEDFGGDSDDNMDE 215
G G D DE
Sbjct: 283 GSVRSGSGTDGSDE 296
Score = 38.5 bits (88), Expect = 0.004
Identities = 23/71 (32%), Positives = 37/71 (52%), Gaps = 2/71 (2%)
Query: 145 EETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEEETDYIMSYFDNGED 204
+E E E+ EE E++E +E+ EE EE +E+ +EEE EEE + + E+
Sbjct: 192 DEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEE--EEEEEEEEE 249
Query: 205 FGGDSDDNMDE 215
+ D D +E
Sbjct: 250 YEQDERDQKEE 260
Score = 36.6 bits (83), Expect = 0.017
Identities = 22/90 (24%), Positives = 45/90 (50%), Gaps = 1/90 (1%)
Query: 127 ERITILLPKRPPKTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDE- 185
ERI + + +R ++++ +E + E E + DE+ E +EE EE+ +E
Sbjct: 153 ERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEED 212
Query: 186 EEHEEETDYIMSYFDNGEDFGGDSDDNMDE 215
EE EE+ + ++GE+ + ++ +E
Sbjct: 213 EEVEEDAEEDEEVDEDGEEEEEEEEEEEEE 242
>gi|17975763 myelin transcription factor 1 [Homo sapiens]
Length = 1121
Score = 58.5 bits (140), Expect = 4e-09
Identities = 29/49 (59%), Positives = 38/49 (77%)
Query: 145 EETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEEETD 193
EE ++ E E++EEE EE+EE+EEEEE+EEEEEEE +EEE EEE +
Sbjct: 258 EEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 306
Score = 58.5 bits (140), Expect = 4e-09
Identities = 30/54 (55%), Positives = 38/54 (70%)
Query: 142 EDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEEETDYI 195
E+ EE ++ E E+ EEE EE+EE+EEEEE+EEEEEEE +EEE E D I
Sbjct: 259 EEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVI 312
Score = 57.8 bits (138), Expect = 7e-09
Identities = 28/48 (58%), Positives = 38/48 (79%)
Query: 144 KEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEEE 191
+EE ++ E E++EE+ EE+EE+EEEEE+EEEEEEE +EEE EEE
Sbjct: 258 EEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 305
Score = 57.4 bits (137), Expect = 9e-09
Identities = 27/49 (55%), Positives = 39/49 (79%)
Query: 142 EDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEE 190
E+++E ++ E E+++EE EE+EE+EEEEE+EEEEEEE +EEE EE
Sbjct: 258 EEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 306
Score = 56.6 bits (135), Expect = 2e-08
Identities = 30/63 (47%), Positives = 43/63 (68%), Gaps = 7/63 (11%)
Query: 138 PKTTED-------KEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEE 190
P++ ED K++ I E +++EEE EE+E++EEEEE+EEEEEEE +EEE EE
Sbjct: 237 PQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEE 296
Query: 191 ETD 193
E +
Sbjct: 297 EEE 299
Score = 55.8 bits (133), Expect = 3e-08
Identities = 29/73 (39%), Positives = 46/73 (63%)
Query: 121 VRKLQKERITILLPKRPPKTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEE 180
V ++ ER L P+ ++ + + + E+++EE EE+EE+E+EEE+EEEEE
Sbjct: 224 VVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEE 283
Query: 181 EEYDEEEHEEETD 193
EE +EEE EEE +
Sbjct: 284 EEEEEEEEEEEEE 296
Score = 51.6 bits (122), Expect = 5e-07
Identities = 28/69 (40%), Positives = 44/69 (63%)
Query: 114 PRELKIRVRKLQKERITILLPKRPPKTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEE 173
P+ L+ + ++ IL + + E++EE ++ E E++EEE EE+EE+EEEE
Sbjct: 237 PQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEE 296
Query: 174 EKEEEEEEE 182
E+EEEEEEE
Sbjct: 297 EEEEEEEEE 305
Score = 50.4 bits (119), Expect = 1e-06
Identities = 25/53 (47%), Positives = 37/53 (69%)
Query: 142 EDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEEETDY 194
E++EE + E E++EEE EE+EE+EEEEE+EEEEEE + +E+T +
Sbjct: 267 EEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSH 319
Score = 46.6 bits (109), Expect = 2e-05
Identities = 32/97 (32%), Positives = 52/97 (53%), Gaps = 7/97 (7%)
Query: 127 ERITILLPKRPPKTTEDKEETIQKL--ETLEKKEEEVTSEED-----EEKEEEEEKEEEE 179
E+ + P+ + E E Q L ++LE E +S++ EE++EEEE+EEEE
Sbjct: 211 EKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEE 270
Query: 180 EEEYDEEEHEEETDYIMSYFDNGEDFGGDSDDNMDEA 216
EEE +EEE EEE + + E+ + ++ +EA
Sbjct: 271 EEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEA 307
Score = 42.0 bits (97), Expect = 4e-04
Identities = 21/51 (41%), Positives = 33/51 (64%)
Query: 142 EDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEEET 192
E++E+ ++ E E++EEE EE+EE+EEEEE+EEE + +E T
Sbjct: 270 EEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHT 320
Score = 29.6 bits (65), Expect = 2.1
Identities = 15/50 (30%), Positives = 28/50 (56%)
Query: 142 EDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEEE 191
E++EE ++ E E++EEE EE+EE+E + +E+ + + E
Sbjct: 278 EEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPE 327
>gi|118600967 shroom family member 4 [Homo sapiens]
Length = 1493
Score = 55.8 bits (133), Expect = 3e-08
Identities = 25/58 (43%), Positives = 39/58 (67%)
Query: 134 PKRPPKTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEEE 191
P RPP +K + + ++++++ +E+EE+EEEEE+EEEEEEE + EE EEE
Sbjct: 1101 PPRPPPPNWEKYRLFRAAQQQKQQQQQQKQQEEEEEEEEEEEEEEEEEEEEAEEEEEE 1158
Score = 33.1 bits (74), Expect = 0.19
Identities = 16/49 (32%), Positives = 29/49 (59%)
Query: 127 ERITILLPKRPPKTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEK 175
E+ + + K + +++ ++ E E++EEE EE+EE EEEEE+
Sbjct: 1110 EKYRLFRAAQQQKQQQQQQKQQEEEEEEEEEEEEEEEEEEEEAEEEEEE 1158
Score = 30.4 bits (67), Expect = 1.2
Identities = 15/49 (30%), Positives = 29/49 (59%)
Query: 125 QKERITILLPKRPPKTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEE 173
+K R+ ++ + + K++ ++ E E++EEE EE+ E+EEEE
Sbjct: 1110 EKYRLFRAAQQQKQQQQQQKQQEEEEEEEEEEEEEEEEEEEEAEEEEEE 1158
>gi|155030232 proline, glutamic acid and leucine rich protein 1
[Homo sapiens]
Length = 1130
Score = 55.8 bits (133), Expect = 3e-08
Identities = 31/84 (36%), Positives = 50/84 (59%), Gaps = 7/84 (8%)
Query: 137 PPKTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKE-----EEEEEEYDEEEHEEE 191
PP ED T+ + + +++EEE EE+EE+EEEEE+E EE+EEEY EEE EEE
Sbjct: 871 PPALEEDL--TVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEE 928
Query: 192 TDYIMSYFDNGEDFGGDSDDNMDE 215
++ + + + + ++ +E
Sbjct: 929 EEFEEEFEEEEGELEEEEEEEDEE 952
Score = 49.7 bits (117), Expect = 2e-06
Identities = 28/55 (50%), Positives = 37/55 (67%), Gaps = 3/55 (5%)
Query: 142 EDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEE---EEYDEEEHEEETD 193
E++EE + E E+ EEE EE+EE+EE EE+ EEEE EE +EEE EEE +
Sbjct: 901 EEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEE 955
Score = 49.3 bits (116), Expect = 3e-06
Identities = 27/71 (38%), Positives = 46/71 (64%), Gaps = 3/71 (4%)
Query: 126 KERITILLPKRPPKTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEE---EEE 182
+E +T++ + E++EE ++ E E++EE+ EE++E+E EE+EEEE EEE
Sbjct: 875 EEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEE 934
Query: 183 YDEEEHEEETD 193
++EEE E E +
Sbjct: 935 FEEEEGELEEE 945
Score = 48.1 bits (113), Expect = 6e-06
Identities = 26/52 (50%), Positives = 36/52 (69%)
Query: 142 EDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEEETD 193
E++EE ++ E++EEE EE EE+E E E+EEEEE+E +EEE EE D
Sbjct: 911 EEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVED 962
Score = 46.2 bits (108), Expect = 2e-05
Identities = 25/50 (50%), Positives = 34/50 (68%)
Query: 142 EDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEEE 191
ED+EE ++ E E++ EE EE+ E EEEEE+E+EEEEE EE + E
Sbjct: 915 EDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLE 964
Score = 37.0 bits (84), Expect = 0.013
Identities = 22/51 (43%), Positives = 32/51 (62%), Gaps = 1/51 (1%)
Query: 142 EDKEETIQKLETLEKKEEEVTSEEDEE-KEEEEEKEEEEEEEYDEEEHEEE 191
E++EE + E E++E E+ EE+EE +EEEEE EE E+ E+ E E
Sbjct: 923 EEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVE 973
Score = 32.0 bits (71), Expect = 0.42
Identities = 45/163 (27%), Positives = 68/163 (41%), Gaps = 40/163 (24%)
Query: 29 ALPPPTLQPSPLFPPLEFRPVPLPSGE-EGEYVLALKQ----ELRGAMRQLPYFIRPAVP 83
A PPPTL P+ PP E P P E E +L +++ E RGA P A+P
Sbjct: 976 APPPPTLPPA--LPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGA-DTAPTLAPEALP 1032
Query: 84 KR-DVERYSDKYQMSGPIDNAIDWNPDWRRLPRELKIRVRKLQKERITILLPKRPPKTTE 142
+ +VER + P P+EL +++E P PP E
Sbjct: 1033 SQGEVEREGESPAAGPP--------------PQEL------VEEE------PSAPPTLLE 1066
Query: 143 DKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDE 185
++ E + +K + + +EE E E E E +E+E D+
Sbjct: 1067 EETE-----DGSDKVQPPPETPAEEEMETETEAEALQEKEQDD 1104
>gi|239757046 PREDICTED: similar to hCG1790759 [Homo sapiens]
Length = 737
Score = 55.1 bits (131), Expect = 5e-08
Identities = 25/50 (50%), Positives = 38/50 (76%), Gaps = 1/50 (2%)
Query: 45 EFRPVPLPSGEEGEYVLALKQELRGAMRQLPYFIRPAVPKRDVERYSDKY 94
+++ VPL + +E EY+LALKQELR M+++PYFI ++D+ERYS +Y
Sbjct: 439 DYKSVPLKTEDE-EYMLALKQELRETMKRMPYFIETPEERQDIERYSKRY 487
>gi|239751558 PREDICTED: similar to hCG1790759 [Homo sapiens]
Length = 771
Score = 55.1 bits (131), Expect = 5e-08
Identities = 25/50 (50%), Positives = 38/50 (76%), Gaps = 1/50 (2%)
Query: 45 EFRPVPLPSGEEGEYVLALKQELRGAMRQLPYFIRPAVPKRDVERYSDKY 94
+++ VPL + +E EY+LALKQELR M+++PYFI ++D+ERYS +Y
Sbjct: 473 DYKSVPLKTEDE-EYMLALKQELRETMKRMPYFIETPEERQDIERYSKRY 521
>gi|169212818 PREDICTED: similar to hCG1790759 [Homo sapiens]
Length = 771
Score = 55.1 bits (131), Expect = 5e-08
Identities = 25/50 (50%), Positives = 38/50 (76%), Gaps = 1/50 (2%)
Query: 45 EFRPVPLPSGEEGEYVLALKQELRGAMRQLPYFIRPAVPKRDVERYSDKY 94
+++ VPL + +E EY+LALKQELR M+++PYFI ++D+ERYS +Y
Sbjct: 473 DYKSVPLKTEDE-EYMLALKQELRETMKRMPYFIETPEERQDIERYSKRY 521
>gi|169210053 PREDICTED: hypothetical protein [Homo sapiens]
Length = 185
Score = 54.7 bits (130), Expect = 6e-08
Identities = 26/61 (42%), Positives = 43/61 (70%)
Query: 133 LPKRPPKTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEEET 192
LP + E++EE ++ + EK+E+E E++EEKEE+EE+EE+E ++ +EE+ EEE
Sbjct: 116 LPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEI 175
Query: 193 D 193
D
Sbjct: 176 D 176
Score = 45.1 bits (105), Expect = 5e-05
Identities = 21/45 (46%), Positives = 33/45 (73%)
Query: 149 QKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEEETD 193
Q L E++ EE E +EE++EEE++E+EEEEE +EE+ E+E +
Sbjct: 114 QGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEE 158
Score = 43.5 bits (101), Expect = 1e-04
Identities = 26/55 (47%), Positives = 38/55 (69%), Gaps = 3/55 (5%)
Query: 142 EDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHE-EETDYI 195
E+KEE ++ E E+KEEE EEDEE+EE+E K+ EEE+ +E + E + T Y+
Sbjct: 133 EEKEEEKEEDEEEEEKEEE--KEEDEEEEEKEGKKMEEEKVEEEIDTEIQRTQYL 185
Score = 40.0 bits (92), Expect = 0.002
Identities = 23/70 (32%), Positives = 40/70 (57%), Gaps = 7/70 (10%)
Query: 117 LKIRVRKLQKERITILLPKRPPKTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKE 176
L + ++++E + ++ + ED+EE EK+EE+ EE+EEKE ++ +E
Sbjct: 116 LPVEEEEVEEEEEEVEEEEKEEEKEEDEEEE-------EKEEEKEEDEEEEEKEGKKMEE 168
Query: 177 EEEEEEYDEE 186
E+ EEE D E
Sbjct: 169 EKVEEEIDTE 178
Score = 36.2 bits (82), Expect = 0.022
Identities = 17/35 (48%), Positives = 25/35 (71%)
Query: 159 EEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEEETD 193
EE ++++ EEEE +EEEEE E +E+E E+E D
Sbjct: 108 EECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEED 142
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 52.8 bits (125), Expect = 2e-07
Identities = 49/182 (26%), Positives = 83/182 (45%), Gaps = 13/182 (7%)
Query: 24 IGKGDALPPPTLQPSPLFPPLEFRPVPLPSGEEGEYVLALKQELRGAMRQLPYFIRPAVP 83
+ K + +PPP + P P E + VP P + E L K R + AV
Sbjct: 9597 VPKKEKVPPPKVPEEPKKPVPE-KKVP-PKVIKMEEPLPAKVTERHMQITQEEKVLVAVT 9654
Query: 84 KRDVE---RYSDKYQMSGPIDNAIDWNPDWRRLP--RELKIRVRKLQKERITILLPKRPP 138
K++ R ++ + + P + + P P + + R R +++E+++I PKR P
Sbjct: 9655 KKEAPPKARVPEEPKRAVPEEKVLKLKPKREEEPPAKVTEFRKRVVKEEKVSIEAPKREP 9714
Query: 139 KTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEE------KEEEEEEEYDEEEHEEET 192
+ ++ +K +EE V+ + +EE EE EE +E E EEYD+ E EE
Sbjct: 9715 QPIKEVTIMEEKERAYTLEEEAVSVQREEEYEEYEEYDYKEFEEYEPTEEYDQYEEYEER 9774
Query: 193 DY 194
+Y
Sbjct: 9775 EY 9776
Score = 46.6 bits (109), Expect = 2e-05
Identities = 43/173 (24%), Positives = 76/173 (43%), Gaps = 18/173 (10%)
Query: 31 PPPTLQPSPLFPPLEFRPVPLPSGEEGEYVLALKQELRGAMRQLPYFIRPAVPKRDVERY 90
PPP P P+ VP+P + +++ ++P + VP++ V
Sbjct: 9999 PPPAKVPEVPKKPVPEEKVPVP----------VPKKVEAPPAKVPEVPKKPVPEKKVPVP 10048
Query: 91 SDKYQMSGPID------NAIDWNPDWRRLPRELKIRVRKLQKERITILLPKRPPKTTED- 143
+ K + P I +P++++ K+ K+R + +P P+ E
Sbjct: 10049 APKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVL 10108
Query: 144 -KEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEEETDYI 195
+EE + + E L ++EE + EE+ EEEE EEEE +EEE E +Y+
Sbjct: 10109 FEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYV 10161
Score = 37.0 bits (84), Expect = 0.013
Identities = 42/183 (22%), Positives = 77/183 (42%), Gaps = 25/183 (13%)
Query: 37 PSPLFPPLEFRPVPLPSGEEGEYVLALKQELRGAMRQLPYFIRPAVPKRDVERYSDKYQM 96
P P+ E P +P ++G + +E + Q PAVP+ ++ ++ +
Sbjct: 9358 PVPVAKKKEAPPAKVPEVQKG----VVTEEKITIVTQREESPPPAVPEIPKKKVPEERKP 9413
Query: 97 SGPIDNAIDWNPDWRRLPRELKIRVRKLQKERITILLP---KRPPKTTEDKEETI----- 148
+ + P LP+ + + +E++ + +P K PP E ++T+
Sbjct: 9414 VPRKEEEVPPPPKVPALPK------KPVPEEKVAVPVPVAKKAPPPRAEVSKKTVVEEKR 9467
Query: 149 ----QKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEE---YDEEEHEEETDYIMSYFDN 201
+KL + EVT E +EE EEEE Y EEE EEE + ++ ++
Sbjct: 9468 FVAEEKLSFAVPQRVEVTRHEVSAEEEWSYSEEEEGVSISVYREEEREEEEEAEVTEYEV 9527
Query: 202 GED 204
E+
Sbjct: 9528 MEE 9530
Score = 36.2 bits (82), Expect = 0.022
Identities = 26/73 (35%), Positives = 38/73 (52%), Gaps = 7/73 (9%)
Query: 126 KERIT---ILLPKR----PPKTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEE 178
K+++T +++PK+ P K E ++ +K L K+EE + E EE EEE EEE
Sbjct: 10191 KKKVTEKKVVIPKKEEAPPAKVPEVPKKVEEKRIILPKEEEVLPVEVTEEPEEEPISEEE 10250
Query: 179 EEEEYDEEEHEEE 191
EE E EE
Sbjct: 10251 IPEEPPSIEEVEE 10263
Score = 35.4 bits (80), Expect = 0.038
Identities = 38/164 (23%), Positives = 77/164 (46%), Gaps = 17/164 (10%)
Query: 37 PSPLFPPLEFRPVPLPSGEEGEYVLALKQELRGAMRQLPYFIRPAVPKRDVERYSDKYQM 96
P P P + + VP EE + V ++E+ + PA+PK+ V + ++
Sbjct: 9395 PPPAVPEIPKKKVP----EERKPVPRKEEEVPPPPKV------PALPKKPVP----EEKV 9440
Query: 97 SGPIDNAIDWNPDWRRLPRELKIRVRK-LQKERITILLPKRPPKTTEDKEETIQKLETLE 155
+ P+ A P + ++ + ++ + +E+++ +P+R T + + + E
Sbjct: 9441 AVPVPVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEVSAEEEWSYSEE 9500
Query: 156 KKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEH--EEETDYIMS 197
++ ++ +EE+EEEEE E E E +E E EE +I+S
Sbjct: 9501 EEGVSISVYREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIIS 9544
Score = 35.4 bits (80), Expect = 0.038
Identities = 48/188 (25%), Positives = 77/188 (40%), Gaps = 31/188 (16%)
Query: 26 KGDALPPPTLQPSPLFPPLEFRPVPL--PSGEEGEYVLALKQELRGAMRQLPYFIRPAVP 83
K + + P + P P+ +P PS EE E V A ++P I+ AVP
Sbjct: 10228 KEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEV---------APPRVPEVIKKAVP 10278
Query: 84 KRDVERYSDKYQMSGPIDNAIDWNPDW--RRLPRELKIRVRKLQKERITILLPKRPPKTT 141
+ P+ ++ P +++P E K+ V +KE +P+ P K
Sbjct: 10279 EAPT-----------PVPKKVEAPPAKVSKKIPEE-KVPVPVQKKEAPPAKVPEVPKKVP 10326
Query: 142 EDK-----EETIQKLETLEKKEEEVTSEEDEEKEEEEEKE-EEEEEEYDEEEHEEETDYI 195
E K +E + + EE+V+ +E +E E E E E +E EEE +
Sbjct: 10327 EKKVLVPKKEAVPPAKGRTVLEEKVSVAFRQEVVVKERLELEVVEAEVEEIPEEEEFHEV 10386
Query: 196 MSYFDNGE 203
YF+ GE
Sbjct: 10387 EEYFEEGE 10394
Score = 35.0 bits (79), Expect = 0.049
Identities = 44/161 (27%), Positives = 67/161 (41%), Gaps = 12/161 (7%)
Query: 31 PPPTLQPSPLFPPLEFRPVPLPSGEEGEYVLALKQELRGAMRQLPYFIRPAVPKRDVERY 90
P P P PP +PVP ++ V+A K EL ++P + VP++ V
Sbjct: 10685 PEPAAPPQVTVPPK--KPVP---EKKAPAVVAKKPELPPV--KVPEVPKEVVPEKKVPLV 10737
Query: 91 SDKYQMSGPIDNAIDWNPDWRRLPRELKIRVRKLQKERITILLPKRPPKTTEDKEETIQK 150
K + P + P + + E K+ V K + E +P+ P K +++ +
Sbjct: 10738 VPKKPEAPPAK--VPEVP--KEVVPEKKVAVPK-KPEVPPAKVPEVPKKPVLEEKPAVPV 10792
Query: 151 LETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEEE 191
E E EV E +E EEE EEE+ EE E E
Sbjct: 10793 PERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPE 10833
Score = 34.7 bits (78), Expect = 0.065
Identities = 27/91 (29%), Positives = 44/91 (48%), Gaps = 14/91 (15%)
Query: 116 ELKIRVRKLQKERIT---ILLPKRPPKTTEDKEETIQKLETL----------EKKEEEVT 162
+++I + K +KE++T +P +P + +++ + + E E + EEV
Sbjct: 9850 KIRISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPKELEPEEVA 9909
Query: 163 SEEDEEKEEEEEKEEEEEEEYDEEEHEEETD 193
EE E EE EEEEEY EE E T+
Sbjct: 9910 FEE-EVVTHVEEYLVEEEEEYIHEEEEFITE 9939
Score = 33.9 bits (76), Expect = 0.11
Identities = 31/110 (28%), Positives = 49/110 (44%), Gaps = 7/110 (6%)
Query: 80 PAVPKRDVERYSDKYQMSGPIDNAIDWNPDWRRLPRELK--IRVRKLQKERITILLPKRP 137
P VP+ + + +K ++S ++P + K + K+ R + P R
Sbjct: 9837 PKVPEEPKKVFEEKIRISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRV 9896
Query: 138 PKTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEE 187
P+ ++ E E + +EE VT E+ EEEEE EEEE EEE
Sbjct: 9897 PEVPKELEP-----EEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEE 9941
Score = 32.3 bits (72), Expect = 0.32
Identities = 21/54 (38%), Positives = 31/54 (57%), Gaps = 4/54 (7%)
Query: 142 EDKEETIQKLETLEKKEEEVTSEED-EEKEEEEEKEE---EEEEEYDEEEHEEE 191
E+ +E ++++ KKE EED EE +E E+EE E EEE++E E E
Sbjct: 9095 EEPDEDYEEIKVEAKKEVHEEWEEDFEEGQEYYEREEGYDEGEEEWEEAYQERE 9148
Score = 31.6 bits (70), Expect = 0.55
Identities = 53/207 (25%), Positives = 83/207 (40%), Gaps = 42/207 (20%)
Query: 30 LPPPTLQPSPLFPPLEFRPV---PLPSGEEGEYVLALKQELRGAMRQLPYFIRPAVPKRD 86
+P PT+ P PP E PV P+P +L +E + +++ + K+D
Sbjct: 8942 VPIPTM-PIRAVPPEEIPPVVAPPIP------LLLPTPEEKKPPPKRIE--VTKKAVKKD 8992
Query: 87 VERYSDKYQMSGPIDNAIDWNP--------------DWRRLPRELKI----RVRKLQKER 128
++ K + P + + P D E+KI R +++QKE+
Sbjct: 8993 AKKVVAKPKEMTPREEIVKKPPPPTTLIPAKAPEIIDVSSKAEEVKIMTITRKKEVQKEK 9052
Query: 129 ITILLPKRPPKTT-----EDKEETIQKLET---LEKKEEEVTSEEDEEKEE---EEEKEE 177
+ K+ E EE +LE E E+ E DE+ EE E +KE
Sbjct: 9053 EAVYEKKQAVHKEKRVFIESFEEPYDELEVEPYTEPFEQPYYEEPDEDYEEIKVEAKKEV 9112
Query: 178 EEEEEYDEEEHEEETDYIMSYFDNGED 204
EE E D EE +E + Y D GE+
Sbjct: 9113 HEEWEEDFEEGQEYYEREEGY-DEGEE 9138
Score = 31.6 bits (70), Expect = 0.55
Identities = 34/162 (20%), Positives = 67/162 (41%), Gaps = 24/162 (14%)
Query: 32 PPTLQPSPLFPPLEFRPVPLPSGEEGEYVLALKQELRGAMRQLPYFIRPAVPKRDVERYS 91
P + P PP++ VP E + L + ++ ++P + VP++ V
Sbjct: 10707 PAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKV---- 10762
Query: 92 DKYQMSGPIDNAIDWNPDW--RRLPRELKIRVRKLQKERITILLPKR----PPKTTEDKE 145
A+ P+ ++P K + + +E+ + +P+R PP+ E+ E
Sbjct: 10763 -----------AVPKKPEVPPAKVPEVPK---KPVLEEKPAVPVPERAESPPPEVYEEPE 10808
Query: 146 ETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEE 187
E + E ++E+ V E+EE E EE ++ E+
Sbjct: 10809 EIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEK 10850
Score = 30.4 bits (67), Expect = 1.2
Identities = 26/71 (36%), Positives = 33/71 (46%), Gaps = 16/71 (22%)
Query: 137 PPKTTEDKEETIQKLETLEKKEE-------EVTSEEDEE-----KEEE----EEKEEEEE 180
P E K++ +K + KKEE EV + +E+ KEEE E EE EE
Sbjct: 10184 PAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKVEEKRIILPKEEEVLPVEVTEEPEE 10243
Query: 181 EEYDEEEHEEE 191
E EEE EE
Sbjct: 10244 EPISEEEIPEE 10254
Score = 29.3 bits (64), Expect = 2.7
Identities = 22/76 (28%), Positives = 38/76 (50%), Gaps = 5/76 (6%)
Query: 115 RELKIRVRKLQKERITILLPKRPPKTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEE 174
R+ K R R + + LL RP TT+ E +L+ + K+E+ S + ++ E
Sbjct: 32188 RQPKQRQRIMAEREDEELL--RPVTTTQHLSEYKSELDFMSKEEK---SRKKSRRQREVT 32242
Query: 175 KEEEEEEEYDEEEHEE 190
+ E EEEY+ +H +
Sbjct: 32243 EITEIEEEYEISKHAQ 32258
Score = 28.5 bits (62), Expect = 4.6
Identities = 15/44 (34%), Positives = 20/44 (45%)
Query: 160 EVTSEEDEEKEEEEEKEEEEEEEYDEEEHEEETDYIMSYFDNGE 203
E+ + EE+ E EE E E DE+E EE +I E
Sbjct: 8611 ELLKQSQEEETHRLEIEEIERSERDEKEFEELVSFIQQRLSQTE 8654
Score = 28.5 bits (62), Expect = 4.6
Identities = 38/172 (22%), Positives = 72/172 (41%), Gaps = 20/172 (11%)
Query: 32 PPTLQPSPLFPPLEFRPVPLPSGEEGEYVL-ALKQELRGAM--RQLPYFIRPAVP---KR 85
P + P P E +PVP+ EE E A+ +E + + +++P +P P +
Sbjct: 10807 PEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEP 10866
Query: 86 DVERYSDKYQMSGPIDNAIDWNPDWRRLPRELKIRVRKLQKERITILLPKRPPKTTEDKE 145
+ E+ +K ++ P P + ++ + Q + I P+ E E
Sbjct: 10867 EPEKVIEKPKLKPR-------PPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVE 10919
Query: 146 ETIQKLETLEKKEEEVTSEEDEEKEEE-------EEKEEEEEEEYDEEEHEE 190
T K+ EKK ++ E E +EE ++ EEEE + + ++ E+
Sbjct: 10920 LTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEK 10971
Score = 28.1 bits (61), Expect = 6.0
Identities = 13/35 (37%), Positives = 22/35 (62%)
Query: 148 IQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEE 182
+Q E L++ +EE T + E+ E E++E+E EE
Sbjct: 8607 LQAFELLKQSQEEETHRLEIEEIERSERDEKEFEE 8641
>gi|239745093 PREDICTED: hypothetical protein XP_002343359 [Homo
sapiens]
Length = 142
Score = 52.8 bits (125), Expect = 2e-07
Identities = 30/63 (47%), Positives = 41/63 (65%), Gaps = 3/63 (4%)
Query: 135 KRPPKTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEEETDY 194
+R K E+K ++ E EK+ E E++EEKEEEEE EEEEEEE +EEE EEE +
Sbjct: 67 RREEKRREEKRREEKRRE--EKRREGKRREKEEEKEEEEE-EEEEEEEEEEEEEEEEVSF 123
Query: 195 IMS 197
++
Sbjct: 124 SLA 126
Score = 50.1 bits (118), Expect = 1e-06
Identities = 24/55 (43%), Positives = 37/55 (67%)
Query: 139 KTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEEETD 193
+ ++ +EE ++ + E+K E E + +E+EEEKEEEEEEE +EEE EEE +
Sbjct: 63 RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEE 117
Score = 49.3 bits (116), Expect = 3e-06
Identities = 26/59 (44%), Positives = 35/59 (59%)
Query: 135 KRPPKTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEEETD 193
+R K E+K ++ E E+KEEE EE+EE+EEEEE+EEE E E ET+
Sbjct: 77 RREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETE 135
Score = 48.1 bits (113), Expect = 6e-06
Identities = 24/62 (38%), Positives = 38/62 (61%)
Query: 136 RPPKTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEEETDYI 195
R + E+K ++ E ++E+ + E++EE+EE+EEEEEEE +EEE EEE +
Sbjct: 63 RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVS 122
Query: 196 MS 197
S
Sbjct: 123 FS 124
Score = 47.4 bits (111), Expect = 1e-05
Identities = 24/60 (40%), Positives = 38/60 (63%)
Query: 139 KTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEEETDYIMSY 198
K+ +E+ ++ EK+ EE E ++EEE++EEEEEEE +EEE EEE + +S+
Sbjct: 64 KSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSF 123
Score = 43.9 bits (102), Expect = 1e-04
Identities = 22/54 (40%), Positives = 32/54 (59%)
Query: 140 TTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEEETD 193
T+ K + ++ EK+ EE EE + + EKEEE+EEE +EEE EEE +
Sbjct: 60 TSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEE 113
Score = 28.5 bits (62), Expect = 4.6
Identities = 19/68 (27%), Positives = 34/68 (50%)
Query: 115 RELKIRVRKLQKERITILLPKRPPKTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEE 174
RE K R K ++E+ + + +++E+ ++ E E++EEE EE+E
Sbjct: 68 REEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLAT 127
Query: 175 KEEEEEEE 182
+E E E E
Sbjct: 128 RERETETE 135
Score = 27.7 bits (60), Expect = 7.9
Identities = 18/57 (31%), Positives = 31/57 (54%), Gaps = 3/57 (5%)
Query: 122 RKLQKERITILLPKRPPKTTEDKEETIQKLETLEKKEEEVT---SEEDEEKEEEEEK 175
R+ +K R K K E++EE ++ E E++EEEV+ + + E E EE++
Sbjct: 82 RREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKR 138
>gi|4757900 calreticulin precursor [Homo sapiens]
Length = 417
Score = 52.8 bits (125), Expect = 2e-07
Identities = 24/57 (42%), Positives = 40/57 (70%)
Query: 135 KRPPKTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEEE 191
K K +DK++ Q+L+ E+ ++ EE E+KE++E+K+E+EE+E D+EE EEE
Sbjct: 351 KAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEE 407
Score = 44.3 bits (103), Expect = 8e-05
Identities = 21/59 (35%), Positives = 37/59 (62%)
Query: 155 EKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEEETDYIMSYFDNGEDFGGDSDDNM 213
+K++EE +E+EE ++ +E+EE E++E DE++ E+E D D ED G + D +
Sbjct: 359 DKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEEDVPGQAKDEL 417
Score = 43.5 bits (101), Expect = 1e-04
Identities = 17/51 (33%), Positives = 38/51 (74%)
Query: 139 KTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHE 189
K +D+E+ +++ E +K++EE +E+ E+ E+++E EE+EE++ ++EE +
Sbjct: 358 KDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEED 408
Score = 32.3 bits (72), Expect = 0.32
Identities = 17/51 (33%), Positives = 29/51 (56%), Gaps = 7/51 (13%)
Query: 165 EDEEKEEEEEKEEEEEEEYDEEEHEEETDYIMSYFDNGEDFGGDSDDNMDE 215
+D++ EE+ KEEEE+++ EEE E+ ++ ED D +D D+
Sbjct: 358 KDKQDEEQRLKEEEEDKKRKEEEEAEDK-------EDDEDKDEDEEDEEDK 401
Score = 30.8 bits (68), Expect = 0.93
Identities = 19/58 (32%), Positives = 33/58 (56%), Gaps = 6/58 (10%)
Query: 158 EEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEEETDYIMSYFDNGEDFGGDSDDNMDE 215
E+++ ++DEE+ +EE EE+++ +EEE E++ D D ED + D DE
Sbjct: 354 EKQMKDKQDEEQRLKEE--EEDKKRKEEEEAEDKED----DEDKDEDEEDEEDKEEDE 405
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 52.4 bits (124), Expect = 3e-07
Identities = 26/51 (50%), Positives = 37/51 (72%), Gaps = 4/51 (7%)
Query: 141 TEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEEE 191
+E+ E + +LE K+E ++SEE+EE+EEEEE+EEEE E +EE EEE
Sbjct: 2227 SEEMESLLDELE----KQESLSSEEEEEREEEEEREEEEVREEEEERKEEE 2273
Score = 49.7 bits (117), Expect = 2e-06
Identities = 30/90 (33%), Positives = 49/90 (54%), Gaps = 6/90 (6%)
Query: 127 ERITILLPKRPPKTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEE------EKEEEEE 180
E + LL + + + EE ++ E E++EEEV EE+E KEEEE EKEEEE+
Sbjct: 2228 EEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEK 2287
Query: 181 EEYDEEEHEEETDYIMSYFDNGEDFGGDSD 210
++ +E+ +EE F+ E+ + +
Sbjct: 2288 KKKKKEKKKEEVQEKEEVFEEKEEIMSEEE 2317
Score = 46.2 bits (108), Expect = 2e-05
Identities = 30/86 (34%), Positives = 50/86 (58%), Gaps = 4/86 (4%)
Query: 116 ELKIRVRKLQKERITILLPKRPPKTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEE-- 173
E++ + +L+K+ + + E++EE + E E+KEEE E+ EKEEEE
Sbjct: 2229 EMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKK 2288
Query: 174 --EKEEEEEEEYDEEEHEEETDYIMS 197
+KE+++EE ++EE EE + IMS
Sbjct: 2289 KKKKEKKKEEVQEKEEVFEEKEEIMS 2314
Score = 45.8 bits (107), Expect = 3e-05
Identities = 26/83 (31%), Positives = 49/83 (59%), Gaps = 4/83 (4%)
Query: 133 LPKRPPKTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEEET 192
L K+ ++E++EE E E++EEE EE+EE++EEEE EE++ E+ +EE+ +++
Sbjct: 2237 LEKQESLSSEEEEER----EEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKK 2292
Query: 193 DYIMSYFDNGEDFGGDSDDNMDE 215
+ E+ + ++ M E
Sbjct: 2293 EKKKEEVQEKEEVFEEKEEIMSE 2315
Score = 45.4 bits (106), Expect = 4e-05
Identities = 23/50 (46%), Positives = 33/50 (66%)
Query: 143 DKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEEET 192
+KEE +K + EKK+EEV +E+ +E+EE EEE E +EE EEE+
Sbjct: 2281 EKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEES 2330
Score = 43.5 bits (101), Expect = 1e-04
Identities = 22/52 (42%), Positives = 33/52 (63%)
Query: 142 EDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEEETD 193
E +E +++E+L + E+ S EE+EE EE+EE EEEE EEE E + +
Sbjct: 2221 ESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEE 2272
Score = 42.7 bits (99), Expect = 2e-04
Identities = 22/56 (39%), Positives = 36/56 (64%), Gaps = 3/56 (5%)
Query: 135 KRPPKTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEE---EEEYDEEE 187
++ K E K+E +Q+ E + +++EE+ SEE+ E +EE+EEE EEE D E+
Sbjct: 2286 EKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREK 2341
Score = 41.6 bits (96), Expect = 5e-04
Identities = 23/57 (40%), Positives = 32/57 (56%)
Query: 135 KRPPKTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEEE 191
KR K E + ++E+ E EE+ S DE +++E EEEEE +EEE EEE
Sbjct: 2204 KRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEE 2260
Score = 41.2 bits (95), Expect = 7e-04
Identities = 22/52 (42%), Positives = 35/52 (67%)
Query: 142 EDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEEETD 193
E KEE + + +EK+EEE ++ E+K+EE +++EE EE +E EEET+
Sbjct: 2268 ERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETE 2319
Score = 36.6 bits (83), Expect = 0.017
Identities = 20/55 (36%), Positives = 34/55 (61%)
Query: 133 LPKRPPKTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEE 187
LP+R ++E Q+LE LE EE++ +E+E +EE + EE+++ +EEE
Sbjct: 1700 LPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEE 1754
Score = 35.0 bits (79), Expect = 0.049
Identities = 17/35 (48%), Positives = 26/35 (74%), Gaps = 1/35 (2%)
Query: 156 KKEEEVTSEEDEEKE-EEEEKEEEEEEEYDEEEHE 189
K EEEVT EE+ +E EE+E++ EE+ + +EEH+
Sbjct: 1539 KDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHK 1573
Score = 35.0 bits (79), Expect = 0.049
Identities = 25/61 (40%), Positives = 33/61 (54%), Gaps = 6/61 (9%)
Query: 139 KTTEDKEETIQKLETLEKKEE-----EVTSEEDE-EKEEEEEKEEEEEEEYDEEEHEEET 192
K E +EE +K + +KKEE EV E++E EEE E +EEEE + EEE
Sbjct: 2278 KQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEV 2337
Query: 193 D 193
D
Sbjct: 2338 D 2338
Score = 33.9 bits (76), Expect = 0.11
Identities = 22/60 (36%), Positives = 33/60 (55%), Gaps = 1/60 (1%)
Query: 133 LPKRPPKTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKE-EEEEEEYDEEEHEEE 191
L K+ K E K QK+E L ++E+ + +E E +E EE E + EE + EEE +E
Sbjct: 1679 LAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQE 1738
Score = 32.0 bits (71), Expect = 0.42
Identities = 22/90 (24%), Positives = 43/90 (47%), Gaps = 4/90 (4%)
Query: 106 WNPDW--RRLPRELKIRVRKLQKERITILLPKRPPKTTEDKEETIQKLETLEKKEEEVTS 163
W +W R L E K+ + +L + E+ ++ + + + + KE++
Sbjct: 1481 WKEEWEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKD 1540
Query: 164 EEDEEKEEEEEKEEEEEEEY--DEEEHEEE 191
EE+ EEE +E EE+E+ +E+ H +E
Sbjct: 1541 EEEVTLEEEVSREGEEKEQQVTEEQRHIQE 1570
Score = 30.4 bits (67), Expect = 1.2
Identities = 24/92 (26%), Positives = 49/92 (53%), Gaps = 9/92 (9%)
Query: 107 NPDWRRLPRELKIRVRKLQKERITIL-----LPKRPPKTTEDKEETIQKLETLEKKEEEV 161
N DW+ +EL + +L+ + + L + K E+K++ ++ E L + E++
Sbjct: 1706 NLDWQE--KELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKL 1763
Query: 162 TSEEDEEKEEEE--EKEEEEEEEYDEEEHEEE 191
+ EE + +EEE +E+E+ ++ E+ EEE
Sbjct: 1764 SEEETKLAQEEELLIQEKEKLAQHKEKMPEEE 1795
Score = 30.4 bits (67), Expect = 1.2
Identities = 22/80 (27%), Positives = 40/80 (50%), Gaps = 8/80 (10%)
Query: 116 ELKIRVRKLQKERITILLPKRPPKTTEDKE------ETIQKLETLEKKEEEVTSEEDEEK 169
EL + +L +E ++ K+ K E++E E + + ET +EEE+ +E E+
Sbjct: 1727 ELSWKEEELNQEEGKLVEEKK--KLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKL 1784
Query: 170 EEEEEKEEEEEEEYDEEEHE 189
+ +EK EEEE + +
Sbjct: 1785 AQHKEKMPEEEERLGRKREQ 1804
Score = 30.0 bits (66), Expect = 1.6
Identities = 27/123 (21%), Positives = 55/123 (44%), Gaps = 25/123 (20%)
Query: 107 NPDWRRLPRELKIRVRKLQKERITILLPKRPPKTTEDKEETIQKLETL---EKKEEEVTS 163
+P+ L + K++ + ++ +L K + +D+EE + E E+KE++VT
Sbjct: 1504 SPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTE 1563
Query: 164 EE-------------------DEEKEEEEEKEEEEEEEYDEEEH---EEETDYIMSYFDN 201
E+ ++++ +EE K +EEE+ +EE +EE +Y
Sbjct: 1564 EQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKI 1623
Query: 202 GED 204
+D
Sbjct: 1624 TQD 1626
Score = 30.0 bits (66), Expect = 1.6
Identities = 23/118 (19%), Positives = 51/118 (43%), Gaps = 16/118 (13%)
Query: 101 DNAIDWNPDWRRLPRELKIRVRKLQ--KERITILLPKRPPKTTEDKEETIQ--------- 149
D + W +W+++ + K Q K+ + L + + E+KE+ +
Sbjct: 1513 DKKLKWE-EWKQVWENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEE 1571
Query: 150 ----KLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEEETDYIMSYFDNGE 203
++ + E+ ++E+ + +EEEK +EE + +EE + Y+ D+ E
Sbjct: 1572 HKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDRE 1629
Score = 30.0 bits (66), Expect = 1.6
Identities = 14/48 (29%), Positives = 29/48 (60%)
Query: 132 LLPKRPPKTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEE 179
+L + K T++KE I+K E L + E+++ ED +++E+ +E+
Sbjct: 1887 ILAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEK 1934
Score = 30.0 bits (66), Expect = 1.6
Identities = 18/57 (31%), Positives = 28/57 (49%), Gaps = 2/57 (3%)
Query: 133 LPKRPPKTTEDKEETIQKLETLEKKEEEVTSEEDE--EKEEEEEKEEEEEEEYDEEE 187
L K K + + K+ + KEE++T EE + K E ++EEE +EEE
Sbjct: 2132 LTKDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGGIEEEE 2188
Score = 29.3 bits (64), Expect = 2.7
Identities = 26/130 (20%), Positives = 54/130 (41%), Gaps = 19/130 (14%)
Query: 105 DWNPDWRRLPRELKIRVRKLQK--ERITILLPKRPPKTTEDKEETIQKLETLEKKEEEVT 162
D++ L ++ K RK +K ++ ++ K T E+ + + E + EEE
Sbjct: 2124 DFSEKRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGG 2183
Query: 163 SEEDE----------------EKEEEEEKEEEEEEEYDEEEH-EEETDYIMSYFDNGEDF 205
EE+E ++ +EK + +E + EEH EE + ++ + E
Sbjct: 2184 IEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESL 2243
Query: 206 GGDSDDNMDE 215
+ ++ +E
Sbjct: 2244 SSEEEEEREE 2253
Score = 28.9 bits (63), Expect = 3.5
Identities = 22/81 (27%), Positives = 36/81 (44%), Gaps = 20/81 (24%)
Query: 133 LPKRPPKTTEDKEETIQKLETLEKKEEEVTSEED--------------------EEKEEE 172
L +R K +++ E+ QK + L KK E+V EE+ EE +
Sbjct: 1644 LAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQR 1703
Query: 173 EEKEEEEEEEYDEEEHEEETD 193
E+ + +E+E +E E E D
Sbjct: 1704 EQNLDWQEKELAQELEELEWD 1724
Score = 28.1 bits (61), Expect = 6.0
Identities = 19/60 (31%), Positives = 31/60 (51%), Gaps = 1/60 (1%)
Query: 121 VRKLQKERITILLPKRPPKTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEE 180
+ K ++++ PK+ K + KE + K++ KEE SEE EE EEK ++E
Sbjct: 1387 ISKKEEKKTFQKSPKQGRKAVQ-KERKVGKIKREMTKEERDMSEEVEEMATLEEKVVKQE 1445
Score = 28.1 bits (61), Expect = 6.0
Identities = 15/48 (31%), Positives = 25/48 (52%)
Query: 139 KTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEE 186
K+ + + +QK + K + E+T EE + EE EE EE+ +E
Sbjct: 1398 KSPKQGRKAVQKERKVGKIKREMTKEERDMSEEVEEMATLEEKVVKQE 1445
Score = 28.1 bits (61), Expect = 6.0
Identities = 20/94 (21%), Positives = 47/94 (50%), Gaps = 7/94 (7%)
Query: 112 RLPRELKIRVRKLQKERITILLPK-----RPPKTTEDKEETIQKLETLEKKEEEVTSEED 166
++ R L ++ R+L E+ + + + + + T+D+++ +K L K + ++E+
Sbjct: 2099 KMKRALFVKERRLSIEQSKLDIKEWDFSEKRSELTKDEKKLARKQRKLANKMRRMINKEE 2158
Query: 167 EEKEEEEEKEEEEEEEY--DEEEHEEETDYIMSY 198
+ EEE + + E DEEE E + ++ +
Sbjct: 2159 KMTEEESKLARKHSEVILDDEEEGGIEEEEVIPF 2192
Score = 28.1 bits (61), Expect = 6.0
Identities = 20/79 (25%), Positives = 43/79 (54%), Gaps = 7/79 (8%)
Query: 116 ELKIRVRKLQKERITILLPKRPPKTTEDKEETIQKLET--LEKKEEEVTSEEDEEKEEEE 173
E K + ++ +KE + + + E+KEE + + ET L +EEE S EE+ + E
Sbjct: 2286 EKKKKKKEKKKEEV-----QEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDRE 2340
Query: 174 EKEEEEEEEYDEEEHEEET 192
++ ++E+++ +E ++
Sbjct: 2341 KEILKKEKQFKLQEQRRKS 2359
>gi|4506411 Ran GTPase activating protein 1 [Homo sapiens]
Length = 587
Score = 52.0 bits (123), Expect = 4e-07
Identities = 25/46 (54%), Positives = 33/46 (71%)
Query: 146 ETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEEE 191
+ + L E +EEE EE+EE+ EEEE+E+EEEEE +EEE EEE
Sbjct: 352 KVLASLSDDEDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEE 397
Score = 50.1 bits (118), Expect = 1e-06
Identities = 24/43 (55%), Positives = 31/43 (72%)
Query: 151 LETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEEETD 193
L +L E+E EE EE+EEE E+EEEE+EE +EEE EEE +
Sbjct: 354 LASLSDDEDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEE 396
Score = 48.9 bits (115), Expect = 3e-06
Identities = 23/37 (62%), Positives = 29/37 (78%)
Query: 155 EKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEEE 191
E++EEE EE+E +EEEEE EEEEEEE +EEE E +
Sbjct: 363 EEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQ 399
Score = 47.0 bits (110), Expect = 1e-05
Identities = 25/51 (49%), Positives = 35/51 (68%), Gaps = 4/51 (7%)
Query: 142 EDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEEET 192
ED+EE E E++EEE EE+E++EEEEE+EEEEEEE + E++
Sbjct: 361 EDEEEE----EEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQRGQGEKS 407
Score = 43.1 bits (100), Expect = 2e-04
Identities = 22/52 (42%), Positives = 32/52 (61%)
Query: 142 EDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEEETD 193
E E+ + LE + + +DE++EEEEE EEEEEE +EEE +EE +
Sbjct: 336 EGCEQLQEVLEGFNMAKVLASLSDDEDEEEEEEGEEEEEEAEEEEEEDEEEE 387
>gi|157694494 MYB binding protein 1a isoform 1 [Homo sapiens]
Length = 1332
Score = 51.6 bits (122), Expect = 5e-07
Identities = 29/100 (29%), Positives = 49/100 (49%), Gaps = 8/100 (8%)
Query: 124 LQKERITILLPKRPPKTTEDKEETI--------QKLETLEKKEEEVTSEEDEEKEEEEEK 175
L + ++L P+T+ED+ + + ++L+ E K EE E EEE E
Sbjct: 681 LTPRALQLILDVLNPETSEDENDRVVVTDDSDERRLKGAEDKSEEGEDNRSSESEEESEG 740
Query: 176 EEEEEEEYDEEEHEEETDYIMSYFDNGEDFGGDSDDNMDE 215
EE EEEE D + + + +M+ G+ GG+ +N +E
Sbjct: 741 EESEEEERDGDVDQGFREQLMTVLQAGKALGGEDSENEEE 780
>gi|157694492 MYB binding protein 1a isoform 2 [Homo sapiens]
Length = 1328
Score = 51.6 bits (122), Expect = 5e-07
Identities = 29/100 (29%), Positives = 49/100 (49%), Gaps = 8/100 (8%)
Query: 124 LQKERITILLPKRPPKTTEDKEETI--------QKLETLEKKEEEVTSEEDEEKEEEEEK 175
L + ++L P+T+ED+ + + ++L+ E K EE E EEE E
Sbjct: 681 LTPRALQLILDVLNPETSEDENDRVVVTDDSDERRLKGAEDKSEEGEDNRSSESEEESEG 740
Query: 176 EEEEEEEYDEEEHEEETDYIMSYFDNGEDFGGDSDDNMDE 215
EE EEEE D + + + +M+ G+ GG+ +N +E
Sbjct: 741 EESEEEERDGDVDQGFREQLMTVLQAGKALGGEDSENEEE 780
>gi|46276863 parathymosin [Homo sapiens]
Length = 102
Score = 51.6 bits (122), Expect = 5e-07
Identities = 33/94 (35%), Positives = 52/94 (55%), Gaps = 12/94 (12%)
Query: 116 ELKIRVRKLQKERITILLPKRPPKTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEK 175
EL + K +KE++ + E K+E +++ E ++EEE T+E+ EE++E EE+
Sbjct: 11 ELSAKDLKEKKEKV-----EEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEE 65
Query: 176 EEEEEEEYDE-------EEHEEETDYIMSYFDNG 202
+EEEEEE DE E E+E D +NG
Sbjct: 66 DEEEEEEDDEGPALKRAAEEEDEADPKRQKTENG 99
Score = 38.9 bits (89), Expect = 0.003
Identities = 25/73 (34%), Positives = 38/73 (52%), Gaps = 2/73 (2%)
Query: 145 EETIQKLETLEKKEEEVTSEEDEEK--EEEEEKEEEEEEEYDEEEHEEETDYIMSYFDNG 202
E++++ L K+ + E+ EEK +E +KE EEEE EE EEET D G
Sbjct: 3 EKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEG 62
Query: 203 EDFGGDSDDNMDE 215
E+ + ++ DE
Sbjct: 63 EEEDEEEEEEDDE 75
Score = 36.2 bits (82), Expect = 0.022
Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 6/75 (8%)
Query: 141 TEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEEETDYIMSYFD 200
+E E +L + KE++ EE ++E +++ EEEE EEE EE + D
Sbjct: 2 SEKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAE------D 55
Query: 201 NGEDFGGDSDDNMDE 215
E+ G+ +D +E
Sbjct: 56 GEEEDEGEEEDEEEE 70
>gi|211904182 DDB1 and CUL4 associated factor 8-like 2 [Homo
sapiens]
Length = 631
Score = 51.2 bits (121), Expect = 7e-07
Identities = 27/64 (42%), Positives = 38/64 (59%)
Query: 152 ETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEEETDYIMSYFDNGEDFGGDSDD 211
ET ++E+E EE E+EEEEE+EEEEEEE +EEE E+ N E + + D
Sbjct: 110 ETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQYSLEEDQ 169
Query: 212 NMDE 215
++E
Sbjct: 170 ALEE 173
Score = 47.8 bits (112), Expect = 7e-06
Identities = 22/40 (55%), Positives = 31/40 (77%)
Query: 152 ETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEEE 191
E E++EE+ +E+ +EEEEE+EEEEEEE +EEE EE+
Sbjct: 109 EETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQ 148
Score = 45.4 bits (106), Expect = 4e-05
Identities = 27/63 (42%), Positives = 37/63 (58%), Gaps = 8/63 (12%)
Query: 139 KTTEDKEETIQKLETL--------EKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEE 190
++ ED E + E+L E+ E E EE +E+ EEE+EEEEEEE +EEE EE
Sbjct: 85 ESLEDFEHFLMSGESLFHYPLVGEEETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEEEE 144
Query: 191 ETD 193
E +
Sbjct: 145 EEE 147
Score = 45.1 bits (105), Expect = 5e-05
Identities = 22/41 (53%), Positives = 31/41 (75%)
Query: 145 EETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDE 185
EE ++ E E+ +EE EE+EE+EEEEE+EEEEEEE ++
Sbjct: 108 EEETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQ 148
Score = 42.7 bits (99), Expect = 2e-04
Identities = 20/45 (44%), Positives = 32/45 (71%)
Query: 138 PKTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEE 182
P E++ E ++ E ++++ E EE+EE+EEEEE+EEEEEE+
Sbjct: 104 PLVGEEETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQ 148
Score = 39.7 bits (91), Expect = 0.002
Identities = 22/64 (34%), Positives = 37/64 (57%), Gaps = 8/64 (12%)
Query: 142 EDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEE--------EEEEYDEEEHEEETD 193
E+++E IQ+ E++EEE EE+EE+EEEEE++ E+Y EE + +
Sbjct: 114 EEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQYSLEEDQALEE 173
Query: 194 YIMS 197
++ S
Sbjct: 174 WVSS 177
>gi|154759293 cysteine-rich hydrophobic domain 1 [Homo sapiens]
Length = 224
Score = 51.2 bits (121), Expect = 7e-07
Identities = 28/68 (41%), Positives = 40/68 (58%), Gaps = 5/68 (7%)
Query: 129 ITILLPKRPPKTT-----EDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEY 183
++ILLP T E++EE + V+ +D+E++EEEE+EEEEEEE
Sbjct: 1 MSILLPNMAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEE 60
Query: 184 DEEEHEEE 191
+EEE EEE
Sbjct: 61 EEEEEEEE 68
Score = 43.5 bits (101), Expect = 1e-04
Identities = 25/66 (37%), Positives = 38/66 (57%), Gaps = 14/66 (21%)
Query: 146 ETIQKLETLEKKEEEVTS--------------EEDEEKEEEEEKEEEEEEEYDEEEHEEE 191
+TI +LE E++E +S +E++E+EEEEE+EEEEEEE +EEE
Sbjct: 12 DTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPP 71
Query: 192 TDYIMS 197
++S
Sbjct: 72 PPRVVS 77
Score = 35.0 bits (79), Expect = 0.049
Identities = 16/34 (47%), Positives = 22/34 (64%)
Query: 155 EKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEH 188
+++EEE EE+EE+EEEEE+E EEH
Sbjct: 47 DEEEEEEEEEEEEEEEEEEEEEAPPPPRVVSEEH 80
Score = 28.1 bits (61), Expect = 6.0
Identities = 17/47 (36%), Positives = 23/47 (48%), Gaps = 7/47 (14%)
Query: 137 PPKTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEY 183
P ED+EE E++EEE EE+EE+EE EE+
Sbjct: 41 PDDDEEDEEEE-------EEEEEEEEEEEEEEEEEAPPPPRVVSEEH 80
>gi|169202818 PREDICTED: similar to hCG1991922 [Homo sapiens]
Length = 488
Score = 50.8 bits (120), Expect = 9e-07
Identities = 24/46 (52%), Positives = 33/46 (71%)
Query: 148 IQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEEETD 193
+ K +KK+EE +EEDEE EEEE+ EE+E+EE DE+E E+ D
Sbjct: 311 VVKAAKSKKKKEEEENEEDEEDEEEEKDEEDEDEEDDEDEEEDGDD 356
Score = 42.4 bits (98), Expect = 3e-04
Identities = 22/50 (44%), Positives = 32/50 (64%), Gaps = 5/50 (10%)
Query: 139 KTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEH 188
K+ + KEE E E+ EE+ E+DEE E+EE+ E+EEE+ DE+ H
Sbjct: 316 KSKKKKEE-----EENEEDEEDEEEEKDEEDEDEEDDEDEEEDGDDEQSH 360
Score = 37.0 bits (84), Expect = 0.013
Identities = 29/84 (34%), Positives = 39/84 (46%), Gaps = 16/84 (19%)
Query: 135 KRPPKTTEDKEETIQKLETLEKKEEE-----VTSEEDEEKEEEEEK--EEEEEEEYDEEE 187
KR K E E+ I K + ++ ++KEEEE + EE+EEEE DEE+
Sbjct: 282 KRSAKLKEKYEKDIAAYRAKGKHDAANNGVVKAAKSKKKKEEEENEEDEEDEEEEKDEED 341
Query: 188 HEEETDYIMSYFDNGEDFGGDSDD 211
+EE D ED D DD
Sbjct: 342 EDEEDD---------EDEEEDGDD 356
Score = 32.0 bits (71), Expect = 0.42
Identities = 15/43 (34%), Positives = 26/43 (60%)
Query: 135 KRPPKTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEE 177
K K E++ E ++ E EK EE+ E+DE++EE+ + E+
Sbjct: 316 KSKKKKEEEENEEDEEDEEEEKDEEDEDEEDDEDEEEDGDDEQ 358
>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
Length = 1184
Score = 50.8 bits (120), Expect = 9e-07
Identities = 32/87 (36%), Positives = 47/87 (54%), Gaps = 9/87 (10%)
Query: 138 PKTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEEETDYIMS 197
P ++++E + E E +EE+ +ED E E+EE+EEEEEEE EEE EE D+ M+
Sbjct: 117 PGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEE--EEEEEENEDHQMN 174
Query: 198 YFD-------NGEDFGGDSDDNMDEAI 217
+ +D D DN DE +
Sbjct: 175 CHNTRIMQDTEKDDNNNDEYDNYDELV 201
Score = 44.7 bits (104), Expect = 6e-05
Identities = 27/95 (28%), Positives = 48/95 (50%), Gaps = 1/95 (1%)
Query: 122 RKLQKERITILLPKRPPKTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEE-EE 180
RK Q ++ PKR P + ++ + + + E+ EEDE +E E+ +E +E
Sbjct: 61 RKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDE 120
Query: 181 EEYDEEEHEEETDYIMSYFDNGEDFGGDSDDNMDE 215
+E DEE EE + I ++ ++ G D +D +E
Sbjct: 121 DEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEE 155
>gi|22749303 hypothetical protein LOC196477 [Homo sapiens]
Length = 406
Score = 50.8 bits (120), Expect = 9e-07
Identities = 29/63 (46%), Positives = 39/63 (61%), Gaps = 1/63 (1%)
Query: 143 DKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEEETDYIMSYFDNG 202
D +E ++ E +E +EEEV EE+EE EE E EE EEE +EEE EEE + + G
Sbjct: 296 DAKEASEEEEEVEDEEEEVEDEEEEE-VEEAEYVEEGEEELEEEELEEEEEVLEENEQRG 354
Query: 203 EDF 205
E+F
Sbjct: 355 EEF 357
Score = 40.0 bits (92), Expect = 0.002
Identities = 25/60 (41%), Positives = 38/60 (63%), Gaps = 6/60 (10%)
Query: 138 PKTTEDKEETIQKLETLEKKEEEV--TSEEDEEKEEEEEKEEEEEEEYDEEEHEEETDYI 195
P E++EE +K + E+ ++EV E EE+EE E++EEE E+E EEE EE +Y+
Sbjct: 273 PLLVEEEEE--KKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDE--EEEEVEEAEYV 328
Score = 38.5 bits (88), Expect = 0.004
Identities = 28/79 (35%), Positives = 36/79 (45%), Gaps = 9/79 (11%)
Query: 135 KRPPKTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEE-----EKEEEEEEEYDEEE-- 187
+ P E Q L L +EEE +DEE+ ++E E EEEEE DEEE
Sbjct: 255 QNPSLAFSPNPEENQSLAPLLVEEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEV 314
Query: 188 --HEEETDYIMSYFDNGED 204
EEE Y + GE+
Sbjct: 315 EDEEEEEVEEAEYVEEGEE 333
Score = 36.6 bits (83), Expect = 0.017
Identities = 22/63 (34%), Positives = 36/63 (57%), Gaps = 5/63 (7%)
Query: 142 EDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEEETDYIMSYFDN 201
+++EE +++ E +E+ EEE+ EE+E EEE+E EE E EE + +S F
Sbjct: 316 DEEEEEVEEAEYVEEGEEEL-----EEEELEEEEEVLEENEQRGEEFHLPLEMPLSIFVE 370
Query: 202 GED 204
E+
Sbjct: 371 AEE 373
Score = 29.3 bits (64), Expect = 2.7
Identities = 19/59 (32%), Positives = 32/59 (54%), Gaps = 16/59 (27%)
Query: 168 EKEEEEEKEEEEEEEYDEE--------EHEEETDYIMSYFDNGEDFGGDSDDNMDEAIY 218
E+EEE++ ++EEEYD+E E EEE + D E+ + ++ ++EA Y
Sbjct: 277 EEEEEKKN--DDEEEYDQEVCDAKEASEEEEEVE------DEEEEVEDEEEEEVEEAEY 327
>gi|21735569 claspin [Homo sapiens]
Length = 1339
Score = 50.4 bits (119), Expect = 1e-06
Identities = 38/105 (36%), Positives = 55/105 (52%), Gaps = 5/105 (4%)
Query: 116 ELKIRVRKLQKERITILLPKRPPKTTEDKEETIQKLETLEKKEEEVT--SEED-EEKEEE 172
+L++ KLQ+ +R + K + E E++EEE+T SEED EEK E+
Sbjct: 593 KLQVLKAKLQEAMKLRRFEERQKRQALFKLDNEDGFEEEEEEEEEMTDESEEDGEEKVEK 652
Query: 173 EEKEE--EEEEEYDEEEHEEETDYIMSYFDNGEDFGGDSDDNMDE 215
EEKEE EEEEE +EEE EE + + E+ + MD+
Sbjct: 653 EEKEEELEEEEEKEEEEEEEGNQETAEFLLSSEEIETKDEKEMDK 697
Score = 45.8 bits (107), Expect = 3e-05
Identities = 26/86 (30%), Positives = 51/86 (59%), Gaps = 2/86 (2%)
Query: 112 RLPRELKIRVRKLQKERITILLPKRPPKTTEDKEETIQKLETLEKKEEEVTSEEDEEKEE 171
+L +K+R + +++R + E++EE + + E+ EE +E++E+E
Sbjct: 600 KLQEAMKLRRFEERQKRQALFKLDNEDGFEEEEEEEEEMTDESEEDGEEKVEKEEKEEEL 659
Query: 172 EEEKEEEEEEEYDEEEHEEETDYIMS 197
EEE+E+EEEEE EE ++E ++++S
Sbjct: 660 EEEEEKEEEEE--EEGNQETAEFLLS 683
Score = 41.2 bits (95), Expect = 7e-04
Identities = 25/62 (40%), Positives = 36/62 (58%), Gaps = 8/62 (12%)
Query: 140 TTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEE--------EEEEEYDEEEHEEE 191
T E +E+ +K+E EK+EE EE EE+EEEE +E EE E DE+E ++E
Sbjct: 639 TDESEEDGEEKVEKEEKEEELEEEEEKEEEEEEEGNQETAEFLLSSEEIETKDEKEMDKE 698
Query: 192 TD 193
+
Sbjct: 699 NN 700
Score = 40.0 bits (92), Expect = 0.002
Identities = 23/69 (33%), Positives = 40/69 (57%), Gaps = 18/69 (26%)
Query: 139 KTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEE--------------EEEEYD 184
++ ED EE ++K E+KEEE+ EE++E+EEEEE +E +E+E D
Sbjct: 641 ESEEDGEEKVEK----EEKEEELEEEEEKEEEEEEEGNQETAEFLLSSEEIETKDEKEMD 696
Query: 185 EEEHEEETD 193
+E ++ ++
Sbjct: 697 KENNDGSSE 705
Score = 30.0 bits (66), Expect = 1.6
Identities = 17/49 (34%), Positives = 24/49 (48%), Gaps = 1/49 (2%)
Query: 139 KTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEE 187
K ED+EE L + E S+EDE + + E+ E+ DEEE
Sbjct: 989 KEEEDEEEEFGDFR-LVSNDNEFDSDEDEHSDSGNDLALEDHEDDDEEE 1036
Score = 28.9 bits (63), Expect = 3.5
Identities = 38/192 (19%), Positives = 71/192 (36%), Gaps = 47/192 (24%)
Query: 57 GEYVLALKQELRGAMRQLPYFIRPAVPKRDVERYSDKYQMSGPIDNAIDWNPDW------ 110
G++ L+ + + + F+ + + + ++ +NA+D N D
Sbjct: 857 GDFQFCLEDDTQSQLLDADGFLNVRNHRNQYQALKPRLPLASMDENAMDANMDELLDLCT 916
Query: 111 --------RRLPRELKIRVRKLQKERITILLPKRPPKTTEDKEETIQKLETLEKKEEEVT 162
+ LPR+ +KE + LL K T T E ++++E
Sbjct: 917 GKFTSQAEKHLPRKSD------KKENMEELLNLCSGKFTSQDASTPASSELNKQEKESSM 970
Query: 163 SEEDEE------------KEEEEEKEE-------EEEEEYDEEEHEEETDYIMSYFDNGE 203
+ EE KEEE+E+EE + E+D +E E + D+G
Sbjct: 971 GDPMEEALALCSGSFPTDKEEEDEEEEFGDFRLVSNDNEFDSDEDE--------HSDSGN 1022
Query: 204 DFGGDSDDNMDE 215
D + ++ DE
Sbjct: 1023 DLALEDHEDDDE 1034
Score = 27.7 bits (60), Expect = 7.9
Identities = 20/64 (31%), Positives = 33/64 (51%), Gaps = 3/64 (4%)
Query: 142 EDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEE-ETDYIMSYFD 200
+D+EE +++ E L+++ EDE E + E+EYD EE +E E D I
Sbjct: 1032 DDEEELLKRSEKLKRQMRLRKYLEDE--AEVSGSDVGSEDEYDGEEIDEYEEDVIDEVLP 1089
Query: 201 NGED 204
+ E+
Sbjct: 1090 SDEE 1093
>gi|156142199 euchromatic histone-lysine N-methyltransferase 2
isoform b [Homo sapiens]
Length = 1176
Score = 50.4 bits (119), Expect = 1e-06
Identities = 24/51 (47%), Positives = 35/51 (68%)
Query: 143 DKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEEETD 193
D +++++ K E E +E+ E+EEEEE+EEEEEEE +EEE EEE +
Sbjct: 275 DSYSVDERVDSDSKSEVEALTEQLSEEEEEEEEEEEEEEEEEEEEEEEEDE 325
Score = 48.5 bits (114), Expect = 4e-06
Identities = 23/31 (74%), Positives = 27/31 (87%)
Query: 160 EVTSEEDEEKEEEEEKEEEEEEEYDEEEHEE 190
E SEE+EE+EEEEE+EEEEEEE +EEE EE
Sbjct: 296 EQLSEEEEEEEEEEEEEEEEEEEEEEEEDEE 326
Score = 48.1 bits (113), Expect = 6e-06
Identities = 23/50 (46%), Positives = 38/50 (76%), Gaps = 1/50 (2%)
Query: 140 TTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHE 189
+ +++ ++ K E +E E+++ EE+EE+EEEEE+EEEEEEE +EE+ E
Sbjct: 278 SVDERVDSDSKSE-VEALTEQLSEEEEEEEEEEEEEEEEEEEEEEEEDEE 326
Score = 46.2 bits (108), Expect = 2e-05
Identities = 25/55 (45%), Positives = 37/55 (67%), Gaps = 4/55 (7%)
Query: 139 KTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEEETD 193
+ D + ++ L T + EEE EE+EE+EEEEE+EEEEEEE ++EE ++D
Sbjct: 282 RVDSDSKSEVEAL-TEQLSEEE---EEEEEEEEEEEEEEEEEEEEEDEESGNQSD 332
Score = 40.4 bits (93), Expect = 0.001
Identities = 19/46 (41%), Positives = 32/46 (69%)
Query: 135 KRPPKTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEE 180
+R ++ + E + + + E++EEE EE+EE+EEEEE+EE+EE
Sbjct: 281 ERVDSDSKSEVEALTEQLSEEEEEEEEEEEEEEEEEEEEEEEEDEE 326
Score = 30.0 bits (66), Expect = 1.6
Identities = 13/55 (23%), Positives = 31/55 (56%)
Query: 141 TEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEEETDYI 195
+E++EE ++ E E++EEE EEDEE + ++ +++ +++ ++
Sbjct: 299 SEEEEEEEEEEEEEEEEEEEEEEEEDEESGNQSDRSGSSGRRKAKKKWRKDSPWV 353
Score = 29.6 bits (65), Expect = 2.1
Identities = 21/86 (24%), Positives = 36/86 (41%)
Query: 131 ILLPKRPPKTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEE 190
+ L K P + E+ E + +L V D + + E E E+ E +EEE EE
Sbjct: 249 VTLTKGDPGSLEEWETVVGDDFSLYYDSYSVDERVDSDSKSEVEALTEQLSEEEEEEEEE 308
Query: 191 ETDYIMSYFDNGEDFGGDSDDNMDEA 216
E + + E+ +S + D +
Sbjct: 309 EEEEEEEEEEEEEEEDEESGNQSDRS 334
>gi|156142197 euchromatic histone-lysine N-methyltransferase 2
isoform a [Homo sapiens]
Length = 1210
Score = 50.4 bits (119), Expect = 1e-06
Identities = 24/51 (47%), Positives = 35/51 (68%)
Query: 143 DKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEEETD 193
D +++++ K E E +E+ E+EEEEE+EEEEEEE +EEE EEE +
Sbjct: 275 DSYSVDERVDSDSKSEVEALTEQLSEEEEEEEEEEEEEEEEEEEEEEEEDE 325
Score = 48.5 bits (114), Expect = 4e-06
Identities = 23/31 (74%), Positives = 27/31 (87%)
Query: 160 EVTSEEDEEKEEEEEKEEEEEEEYDEEEHEE 190
E SEE+EE+EEEEE+EEEEEEE +EEE EE
Sbjct: 296 EQLSEEEEEEEEEEEEEEEEEEEEEEEEDEE 326
Score = 48.1 bits (113), Expect = 6e-06
Identities = 23/50 (46%), Positives = 38/50 (76%), Gaps = 1/50 (2%)
Query: 140 TTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHE 189
+ +++ ++ K E +E E+++ EE+EE+EEEEE+EEEEEEE +EE+ E
Sbjct: 278 SVDERVDSDSKSE-VEALTEQLSEEEEEEEEEEEEEEEEEEEEEEEEDEE 326
Score = 46.2 bits (108), Expect = 2e-05
Identities = 25/55 (45%), Positives = 37/55 (67%), Gaps = 4/55 (7%)
Query: 139 KTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEEETD 193
+ D + ++ L T + EEE EE+EE+EEEEE+EEEEEEE ++EE ++D
Sbjct: 282 RVDSDSKSEVEAL-TEQLSEEE---EEEEEEEEEEEEEEEEEEEEEDEESGNQSD 332
Score = 40.4 bits (93), Expect = 0.001
Identities = 19/46 (41%), Positives = 32/46 (69%)
Query: 135 KRPPKTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEE 180
+R ++ + E + + + E++EEE EE+EE+EEEEE+EE+EE
Sbjct: 281 ERVDSDSKSEVEALTEQLSEEEEEEEEEEEEEEEEEEEEEEEEDEE 326
Score = 30.0 bits (66), Expect = 1.6
Identities = 13/55 (23%), Positives = 31/55 (56%)
Query: 141 TEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEEETDYI 195
+E++EE ++ E E++EEE EEDEE + ++ +++ +++ ++
Sbjct: 299 SEEEEEEEEEEEEEEEEEEEEEEEEDEESGNQSDRSGSSGRRKAKKKWRKDSPWV 353
Score = 29.6 bits (65), Expect = 2.1
Identities = 21/86 (24%), Positives = 36/86 (41%)
Query: 131 ILLPKRPPKTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEE 190
+ L K P + E+ E + +L V D + + E E E+ E +EEE EE
Sbjct: 249 VTLTKGDPGSLEEWETVVGDDFSLYYDSYSVDERVDSDSKSEVEALTEQLSEEEEEEEEE 308
Query: 191 ETDYIMSYFDNGEDFGGDSDDNMDEA 216
E + + E+ +S + D +
Sbjct: 309 EEEEEEEEEEEEEEEDEESGNQSDRS 334
>gi|87298939 hypothetical protein LOC131831 [Homo sapiens]
Length = 663
Score = 50.4 bits (119), Expect = 1e-06
Identities = 34/80 (42%), Positives = 47/80 (58%), Gaps = 9/80 (11%)
Query: 142 EDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEE---HEEETD----Y 194
+D++E+ ++LE E++EEE EE+EE EEEEE+ EEEEEE EEE E+E + +
Sbjct: 16 KDQKESEEELE--EEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAPETF 73
Query: 195 IMSYFDNGEDFGGDSDDNMD 214
Y D G DD D
Sbjct: 74 SEEYLWKVTDIGDYDDDFPD 93
Score = 46.2 bits (108), Expect = 2e-05
Identities = 26/50 (52%), Positives = 36/50 (72%), Gaps = 1/50 (2%)
Query: 156 KKEEEVTSEEDEEKEEEEEKEEEEEE-EYDEEEHEEETDYIMSYFDNGED 204
KK+++ + EE EE+EEEEE EEEEEE E +EEE EEE + ++ GE+
Sbjct: 15 KKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEE 64
Score = 45.8 bits (107), Expect = 3e-05
Identities = 23/40 (57%), Positives = 28/40 (70%)
Query: 150 KLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHE 189
K + E +EE EE+EE EEEEE+ EEEEEE +EEE E
Sbjct: 15 KKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEE 54
Score = 42.4 bits (98), Expect = 3e-04
Identities = 25/55 (45%), Positives = 31/55 (56%)
Query: 136 RPPKTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEE 190
R P D + QK E +EEE E +EE+EE EE+EEE EEE +E EE
Sbjct: 5 RSPSGFGDPGKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEE 59
Score = 38.5 bits (88), Expect = 0.004
Identities = 32/86 (37%), Positives = 45/86 (52%), Gaps = 10/86 (11%)
Query: 122 RKLQKERITILLPKRPPKTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEE---EEKEEE 178
+K QKE L + + E++EE + E++EEEV EE+E EEE EE+E E
Sbjct: 15 KKDQKESEEELEEEEEEEEVEEEEEEV------EEEEEEVEEEEEEVVEEELVGEEQELE 68
Query: 179 EEEEYDEEEHEEETDYIMSYFDNGED 204
E + EE + TD I Y D+ D
Sbjct: 69 APETFSEEYLWKVTD-IGDYDDDFPD 93
Score = 33.5 bits (75), Expect = 0.14
Identities = 15/30 (50%), Positives = 22/30 (73%)
Query: 166 DEEKEEEEEKEEEEEEEYDEEEHEEETDYI 195
D K++++E EEE EEE +EEE EEE + +
Sbjct: 12 DPGKKDQKESEEELEEEEEEEEVEEEEEEV 41
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.135 0.385
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,212,705
Number of Sequences: 37866
Number of extensions: 770842
Number of successful extensions: 56737
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1366
Number of HSP's successfully gapped in prelim test: 526
Number of HSP's that attempted gapping in prelim test: 11479
Number of HSP's gapped (non-prelim): 18932
length of query: 218
length of database: 18,247,518
effective HSP length: 98
effective length of query: 120
effective length of database: 14,536,650
effective search space: 1744398000
effective search space used: 1744398000
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.