Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 8923243
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|8923243 palmdelphin [Homo sapiens]
(551 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|8923243 palmdelphin [Homo sapiens] 1103 0.0
gi|82524851 paralemmin 2 isoform a [Homo sapiens] 177 2e-44
gi|82617626 paralemmin 2 isoform b [Homo sapiens] 158 1e-38
gi|93141031 paralemmin isoform 1 [Homo sapiens] 129 7e-30
gi|22325356 PALM2-AKAP2 protein isoform 2 [Homo sapiens] 120 4e-27
gi|6005709 PALM2-AKAP2 protein isoform 1 [Homo sapiens] 120 4e-27
gi|93141029 paralemmin isoform 2 [Homo sapiens] 90 6e-18
gi|222537747 hypothetical protein LOC342979 [Homo sapiens] 74 3e-13
gi|104526627 triadin [Homo sapiens] 57 6e-08
gi|239735580 TRAF2 and NCK interacting kinase isoform 2 [Homo sa... 53 8e-07
gi|55741807 TRAF2 and NCK interacting kinase isoform 1 [Homo sap... 53 8e-07
gi|148746195 trichohyalin [Homo sapiens] 51 2e-06
gi|94538359 golgi autoantigen, golgin subfamily a, 6B [Homo sapi... 50 7e-06
gi|148839339 nexilin (F actin binding protein) [Homo sapiens] 49 1e-05
gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo sap... 49 2e-05
gi|51472437 PREDICTED: golgi autoantigen, golgin subfamily a, 6C... 49 2e-05
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 49 2e-05
gi|146133848 golgi autoantigen, golgin subfamily a, 6 [Homo sapi... 49 2e-05
gi|19924131 RAD50 homolog isoform 2 [Homo sapiens] 48 2e-05
gi|19924129 RAD50 homolog isoform 1 [Homo sapiens] 48 2e-05
gi|22758136 MAP7 domain containing 2 [Homo sapiens] 48 2e-05
gi|239735588 TRAF2 and NCK interacting kinase isoform 6 [Homo sa... 48 3e-05
gi|239735586 TRAF2 and NCK interacting kinase isoform 5 [Homo sa... 48 3e-05
gi|42794779 myosin 18A isoform b [Homo sapiens] 47 3e-05
gi|28416946 myosin 18A isoform a [Homo sapiens] 47 3e-05
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 47 3e-05
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 47 3e-05
gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap... 47 5e-05
gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens] 47 5e-05
gi|156104874 envoplakin [Homo sapiens] 47 5e-05
>gi|8923243 palmdelphin [Homo sapiens]
Length = 551
Score = 1103 bits (2852), Expect = 0.0
Identities = 551/551 (100%), Positives = 551/551 (100%)
Query: 1 MEEAELVKGRLQAITDKRKIQEEISQKRLKIEEDKLKHQHLKKKALREKWLLDGISSGKE 60
MEEAELVKGRLQAITDKRKIQEEISQKRLKIEEDKLKHQHLKKKALREKWLLDGISSGKE
Sbjct: 1 MEEAELVKGRLQAITDKRKIQEEISQKRLKIEEDKLKHQHLKKKALREKWLLDGISSGKE 60
Query: 61 QEEMKKQNQQDQHQIQVLEQSILRLEKEIQDLEKAELQISTKEEAILKKLKSIERTTEDI 120
QEEMKKQNQQDQHQIQVLEQSILRLEKEIQDLEKAELQISTKEEAILKKLKSIERTTEDI
Sbjct: 61 QEEMKKQNQQDQHQIQVLEQSILRLEKEIQDLEKAELQISTKEEAILKKLKSIERTTEDI 120
Query: 121 IRSVKVEREERAEESIEDIYANIPDLPKSYIPSRLRKEINEEKEDDEQNRKALYAMEIKV 180
IRSVKVEREERAEESIEDIYANIPDLPKSYIPSRLRKEINEEKEDDEQNRKALYAMEIKV
Sbjct: 121 IRSVKVEREERAEESIEDIYANIPDLPKSYIPSRLRKEINEEKEDDEQNRKALYAMEIKV 180
Query: 181 EKDLKTGESTVLSSIPLPSDDFKGTGIKVYDDGQKSVYAVSSNHSAAYNGTDGLAPVEVE 240
EKDLKTGESTVLSSIPLPSDDFKGTGIKVYDDGQKSVYAVSSNHSAAYNGTDGLAPVEVE
Sbjct: 181 EKDLKTGESTVLSSIPLPSDDFKGTGIKVYDDGQKSVYAVSSNHSAAYNGTDGLAPVEVE 240
Query: 241 ELLRQASERNSKSPTEYHEPVYANPFYRPTTPQRETVTPGPNFQERIKIKTNGLGIGVNE 300
ELLRQASERNSKSPTEYHEPVYANPFYRPTTPQRETVTPGPNFQERIKIKTNGLGIGVNE
Sbjct: 241 ELLRQASERNSKSPTEYHEPVYANPFYRPTTPQRETVTPGPNFQERIKIKTNGLGIGVNE 300
Query: 301 SIHNMGNGLSEERGNNFNHISPIPPVPHPRSVIQQAEEKLHTPQKRLMTPWEESNVMQDK 360
SIHNMGNGLSEERGNNFNHISPIPPVPHPRSVIQQAEEKLHTPQKRLMTPWEESNVMQDK
Sbjct: 301 SIHNMGNGLSEERGNNFNHISPIPPVPHPRSVIQQAEEKLHTPQKRLMTPWEESNVMQDK 360
Query: 361 DAPSPKPRLSPRETIFGKSEHQNSSPTCQEDEEDVRYNIVHSLPPDINDTEPVTMIFMGY 420
DAPSPKPRLSPRETIFGKSEHQNSSPTCQEDEEDVRYNIVHSLPPDINDTEPVTMIFMGY
Sbjct: 361 DAPSPKPRLSPRETIFGKSEHQNSSPTCQEDEEDVRYNIVHSLPPDINDTEPVTMIFMGY 420
Query: 421 QQAEDSEEDKKFLTGYDGIIHAELVVIDDEEEEDEGEAEKPSYHPIAPHSQVYQPAKPTP 480
QQAEDSEEDKKFLTGYDGIIHAELVVIDDEEEEDEGEAEKPSYHPIAPHSQVYQPAKPTP
Sbjct: 421 QQAEDSEEDKKFLTGYDGIIHAELVVIDDEEEEDEGEAEKPSYHPIAPHSQVYQPAKPTP 480
Query: 481 LPRKRSEASPHENTNHKSPHKNSISLKEQEESLGSPVHHSPFDAQTTGDGTEDPSLTALR 540
LPRKRSEASPHENTNHKSPHKNSISLKEQEESLGSPVHHSPFDAQTTGDGTEDPSLTALR
Sbjct: 481 LPRKRSEASPHENTNHKSPHKNSISLKEQEESLGSPVHHSPFDAQTTGDGTEDPSLTALR 540
Query: 541 MRMAKLGKKVI 551
MRMAKLGKKVI
Sbjct: 541 MRMAKLGKKVI 551
>gi|82524851 paralemmin 2 isoform a [Homo sapiens]
Length = 413
Score = 177 bits (449), Expect = 2e-44
Identities = 106/250 (42%), Positives = 153/250 (61%), Gaps = 10/250 (4%)
Query: 1 MEEAELVKGRLQAITDKRKIQEEISQKRLKIEEDKLKHQHLKKKALREKWLLDGISSG-- 58
M EAEL K RLQAI +KRK Q EI KR +++E L QH K K LREKWLL GI +G
Sbjct: 3 MAEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTA 62
Query: 59 KEQEEMKKQNQQDQHQIQVLEQSILRLEKEIQDLEKAELQISTKEEAILKKLKSIERTTE 118
+E+E ++Q+++D+ +++ LE +I RLE+EIQ LE E QIS KE+ IL+KLK E++ +
Sbjct: 63 EEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKSFK 122
Query: 119 DIIRSVKVEREERAEESIEDIYANIPDLPKSYIPSRLRKEINEEKEDDEQNRKALYAMEI 178
D + +++ I + +PDLP + SR + +D A+YAMEI
Sbjct: 123 DFQKGF----SSTDGDAVNYISSQLPDLP--ILCSRTAEP--SPGQDGTSRAAAVYAMEI 174
Query: 179 KVEKDLKTGESTVLSSIPLPSDDFKGTGIKVYDDGQKSVYAVSSNHSAAYNGTDGLAPVE 238
VEKD +TGE+ +LS+ + + G+KVYDDG K VY V S + NG L+ +
Sbjct: 175 NVEKDKQTGETKILSTSTIGPEGVHQKGVKVYDDGTKVVYEVRSGGTVVENGVHKLSTKD 234
Query: 239 VEELLRQASE 248
VEEL+++A +
Sbjct: 235 VEELIQKAGQ 244
Score = 61.2 bits (147), Expect = 2e-09
Identities = 39/106 (36%), Positives = 54/106 (50%), Gaps = 13/106 (12%)
Query: 353 ESNVMQDKDAPSPKPRLSPRETIF-----GKSEHQNSSPTCQEDEEDVRYNIVHSLPPDI 407
E V+ D PK + +E + +H + +P Q + P+
Sbjct: 254 ERTVIADGSLSHPKEHMLCKEAKLEMVHKSRKDHSSGNPGQQAQAPS-------AAGPEA 306
Query: 408 NDTEPVTMIFMGYQQAEDSEEDKKFLTGYDGIIHAELVVIDDEEEE 453
N +PVTMIFMGYQ ED EE KK L GYD I AELV+ID+++E+
Sbjct: 307 NLDQPVTMIFMGYQNIEDEEETKKVL-GYDETIKAELVLIDEDDEK 351
>gi|82617626 paralemmin 2 isoform b [Homo sapiens]
Length = 379
Score = 158 bits (400), Expect = 1e-38
Identities = 98/250 (39%), Positives = 138/250 (55%), Gaps = 44/250 (17%)
Query: 1 MEEAELVKGRLQAITDKRKIQEEISQKRLKIEEDKLKHQHLKKKALREKWLLDGISSG-- 58
M EAEL K RLQAI +KRK Q EI KR +++E L QH K K LREKWLL GI +G
Sbjct: 3 MAEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTA 62
Query: 59 KEQEEMKKQNQQDQHQIQVLEQSILRLEKEIQDLEKAELQISTKEEAILKKLKSIERTTE 118
+E+E ++Q+++D+ +++ LE +I RLE+EIQ LE E QIS KE+ IL+KLK E++ +
Sbjct: 63 EEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKSFK 122
Query: 119 DIIRSVKVEREERAEESIEDIYANIPDLPKSYIPSRLRKEINEEKEDDEQNRKALYAMEI 178
D ++ A+YAMEI
Sbjct: 123 DF------------------------------------------QKGFSSTDGAVYAMEI 140
Query: 179 KVEKDLKTGESTVLSSIPLPSDDFKGTGIKVYDDGQKSVYAVSSNHSAAYNGTDGLAPVE 238
VEKD +TGE+ +LS+ + + G+KVYDDG K VY V S + NG L+ +
Sbjct: 141 NVEKDKQTGETKILSTSTIGPEGVHQKGVKVYDDGTKVVYEVRSGGTVVENGVHKLSTKD 200
Query: 239 VEELLRQASE 248
VEEL+++A +
Sbjct: 201 VEELIQKAGQ 210
Score = 61.2 bits (147), Expect = 2e-09
Identities = 39/106 (36%), Positives = 54/106 (50%), Gaps = 13/106 (12%)
Query: 353 ESNVMQDKDAPSPKPRLSPRETIF-----GKSEHQNSSPTCQEDEEDVRYNIVHSLPPDI 407
E V+ D PK + +E + +H + +P Q + P+
Sbjct: 220 ERTVIADGSLSHPKEHMLCKEAKLEMVHKSRKDHSSGNPGQQAQAPS-------AAGPEA 272
Query: 408 NDTEPVTMIFMGYQQAEDSEEDKKFLTGYDGIIHAELVVIDDEEEE 453
N +PVTMIFMGYQ ED EE KK L GYD I AELV+ID+++E+
Sbjct: 273 NLDQPVTMIFMGYQNIEDEEETKKVL-GYDETIKAELVLIDEDDEK 317
>gi|93141031 paralemmin isoform 1 [Homo sapiens]
Length = 387
Score = 129 bits (324), Expect = 7e-30
Identities = 88/241 (36%), Positives = 132/241 (54%), Gaps = 15/241 (6%)
Query: 10 RLQAITDKRKIQEEISQKRLKIEEDKLKHQHLKKKALREKWLLDGI--SSGKEQEEMKKQ 67
RLQAI +KRK Q EI KR ++E+++ + QHLK KALRE+WLL+G S+ + E++++Q
Sbjct: 14 RLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSASEGDEDLRRQ 73
Query: 68 NQQDQHQIQVLEQSILRLEKEIQDLEKAELQISTKEEAILKKLKSIERTTEDIIRSVKVE 127
Q D+ + ++LE S+ RLEKEI+ LE+ + +T +E + + +
Sbjct: 74 MQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKE-------NAAAPSPVRAPAPSPA 126
Query: 128 REERAEESIEDIYANIPDLPKSYIPSRLRKEINEEKEDDEQNRKALYAMEIKVEKDLKTG 187
+EER E + + PK R+ + + A+Y++EI VEKD TG
Sbjct: 127 KEERKTEVVMNSQQTPVGTPKD---KRVSNTPLRTVDGSPMMKAAMYSVEITVEKDKVTG 183
Query: 188 ESTVLSSIPLPSDDFKGTGIKVYDDGQKSVYAVSSNHSAAYNGTDGLAPVEVEELLRQAS 247
E+ VLSS L GIKVY+D K V+AV A NG L+ EV+EL+ +A
Sbjct: 184 ETRVLSSTTLLPRQPLPLGIKVYEDETKVVHAVD---GTAENGIHPLSSSEVDELIHKAD 240
Query: 248 E 248
E
Sbjct: 241 E 241
Score = 52.8 bits (125), Expect = 8e-07
Identities = 39/95 (41%), Positives = 47/95 (49%), Gaps = 15/95 (15%)
Query: 404 PPDINDTE--PVTMIFMGYQQAEDSEEDKKFLTGYDGIIHAELVVIDDEEEEDEGEAEKP 461
PP I + PVTMIFMGYQ ED E KK L G I AELVVI+D E E
Sbjct: 287 PPGIQPGQEPPVTMIFMGYQNVEDEAETKKVL-GLQDTITAELVVIEDAAEPKE------ 339
Query: 462 SYHPIAPHSQVYQPAKPT-PLPRKRSEASPHENTN 495
P P+ +P PT R+ ++A P T+
Sbjct: 340 ---PAPPNGSAAEP--PTEAASREENQAGPEATTS 369
>gi|22325356 PALM2-AKAP2 protein isoform 2 [Homo sapiens]
Length = 1090
Score = 120 bits (300), Expect = 4e-27
Identities = 68/149 (45%), Positives = 97/149 (65%), Gaps = 6/149 (4%)
Query: 1 MEEAELVKGRLQAITDKRKIQEEISQKRLKIEEDKLKHQHLKKKALREKWLLDGISSG-- 58
M EAEL K RLQAI +KRK Q EI KR +++E L QH K K LREKWLL GI +G
Sbjct: 1 MAEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTA 60
Query: 59 KEQEEMKKQNQQDQHQIQVLEQSILRLEKEIQDLEKAELQISTKEEAILKKLKSIERTTE 118
+E+E ++Q+++D+ +++ LE +I RLE+EIQ LE E QIS KE+ IL+KLK E++ +
Sbjct: 61 EEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKSFK 120
Query: 119 DIIRSVKVEREERAEESIEDIYANIPDLP 147
D + +++ I + +PDLP
Sbjct: 121 DFQKGF----SSTDGDAVNYISSQLPDLP 145
>gi|6005709 PALM2-AKAP2 protein isoform 1 [Homo sapiens]
Length = 1103
Score = 120 bits (300), Expect = 4e-27
Identities = 68/149 (45%), Positives = 97/149 (65%), Gaps = 6/149 (4%)
Query: 1 MEEAELVKGRLQAITDKRKIQEEISQKRLKIEEDKLKHQHLKKKALREKWLLDGISSG-- 58
M EAEL K RLQAI +KRK Q EI KR +++E L QH K K LREKWLL GI +G
Sbjct: 1 MAEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTA 60
Query: 59 KEQEEMKKQNQQDQHQIQVLEQSILRLEKEIQDLEKAELQISTKEEAILKKLKSIERTTE 118
+E+E ++Q+++D+ +++ LE +I RLE+EIQ LE E QIS KE+ IL+KLK E++ +
Sbjct: 61 EEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKSFK 120
Query: 119 DIIRSVKVEREERAEESIEDIYANIPDLP 147
D + +++ I + +PDLP
Sbjct: 121 DFQKGF----SSTDGDAVNYISSQLPDLP 145
>gi|93141029 paralemmin isoform 2 [Homo sapiens]
Length = 343
Score = 89.7 bits (221), Expect = 6e-18
Identities = 45/97 (46%), Positives = 70/97 (72%), Gaps = 2/97 (2%)
Query: 10 RLQAITDKRKIQEEISQKRLKIEEDKLKHQHLKKKALREKWLLDGI--SSGKEQEEMKKQ 67
RLQAI +KRK Q EI KR ++E+++ + QHLK KALRE+WLL+G S+ + E++++Q
Sbjct: 14 RLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSASEGDEDLRRQ 73
Query: 68 NQQDQHQIQVLEQSILRLEKEIQDLEKAELQISTKEE 104
Q D+ + ++LE S+ RLEKEI+ LE+ + +T +E
Sbjct: 74 MQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKE 110
Score = 52.8 bits (125), Expect = 8e-07
Identities = 39/95 (41%), Positives = 47/95 (49%), Gaps = 15/95 (15%)
Query: 404 PPDINDTE--PVTMIFMGYQQAEDSEEDKKFLTGYDGIIHAELVVIDDEEEEDEGEAEKP 461
PP I + PVTMIFMGYQ ED E KK L G I AELVVI+D E E
Sbjct: 243 PPGIQPGQEPPVTMIFMGYQNVEDEAETKKVL-GLQDTITAELVVIEDAAEPKE------ 295
Query: 462 SYHPIAPHSQVYQPAKPT-PLPRKRSEASPHENTN 495
P P+ +P PT R+ ++A P T+
Sbjct: 296 ---PAPPNGSAAEP--PTEAASREENQAGPEATTS 325
>gi|222537747 hypothetical protein LOC342979 [Homo sapiens]
Length = 673
Score = 73.9 bits (180), Expect = 3e-13
Identities = 39/101 (38%), Positives = 64/101 (63%), Gaps = 6/101 (5%)
Query: 1 MEEAELVKGRLQAITDKRKIQEEISQKRLKIEEDKLKHQHLKKKALREKWLLDGISSGKE 60
M E+ L + RL+ I +KR++QEEI R ++EE+KL+ + LK+K+LRE+WL+DG ++ E
Sbjct: 1 MAESSLYRQRLEVIAEKRRLQEEIRAARREVEEEKLRVERLKRKSLRERWLMDGAAAVPE 60
Query: 61 QEE------MKKQNQQDQHQIQVLEQSILRLEKEIQDLEKA 95
E + Q Q +I+ LE S+ L+ ++Q L+ A
Sbjct: 61 PSEDPTSKDPQSPEGQAQARIRNLEDSLFTLQSQLQLLQSA 101
>gi|104526627 triadin [Homo sapiens]
Length = 729
Score = 56.6 bits (135), Expect = 6e-08
Identities = 109/517 (21%), Positives = 202/517 (39%), Gaps = 102/517 (19%)
Query: 15 TDKRKIQEEISQKRLKIEEDKLKHQHLKKKALREKWLLDGISSGKEQ-EEMKKQNQQDQH 73
TDK +I E +K+ +I +DK + Q ++ ++ K GKE+ E +K ++ H
Sbjct: 128 TDKGEIDEPPLRKK-EIHKDKTEKQEKPERKIQTKVTHKEKEKGKEKVREKEKPEKKATH 186
Query: 74 QIQVLEQSILRLEKEIQDLEKAELQISTKEEAILKKLKSIERTTEDIIRSVKVEREERAE 133
+++I+ EK E + KE+ KK K+ E++ E + VK ++E+ +
Sbjct: 187 ------------KEKIEKKEKPETKTLAKEQ---KKAKTAEKSEEKTKKEVKGGKQEKVK 231
Query: 134 ESIEDIYANIPDLPKSYIPSRLRKEINEEK------EDDEQNRKALYAMEIKVEKDLKTG 187
++ A + ++ K+ PS+ +++ ++EK E +Q Y ++I V DLK G
Sbjct: 232 QTA----AKVKEVQKT--PSKPKEKEDKEKAAVSKHEQKDQYAFCRYMIDIFVHGDLKPG 285
Query: 188 ESTVLSSIPLPSDDFKGTGIKVYDDGQKSVYAVSSNHSAAYNGTDGLAPVEVEELLRQAS 247
+S + PLP++ ++ A + +E +++ S
Sbjct: 286 QSPAIPP-PLPTEQASRP-----TPASPALEEKEGEKKKAEKKVTSETKKKEKEDIKKKS 339
Query: 248 ERNSKSPTEYHEPVYANPFYRPTTPQRETVTPGPNFQERIKIKTNGLGIGVNESIHNMGN 307
E+ + E EP A+ ET Q +KI
Sbjct: 340 EKETAIDVEKKEPGKAS----------ETK------QGTVKIAAQAA------------- 370
Query: 308 GLSEERGNNFNHISPIPPVPHPRSVIQQAEEKLHTPQKRLMTPWEESNVMQDKDAPSPKP 367
+E+ + V P+ Q+ +EK P K +P +E +V DK +
Sbjct: 371 AKKDEKKEDSKKTKKPAEVEQPKGKKQEKKEKHVEPAK---SPKKEHSVPSDKQVKAKTE 427
Query: 368 R-------LSPRETIFGKSEHQNSSPTCQEDEEDVRYNIVHSLPPDINDTEPVTMIFMGY 420
R +S ++ + GK E + T + E+++R + D EP+
Sbjct: 428 RAKEEIGAVSIKKAVPGKKEEK----TTKTVEQEIRKEKSGKTSSILKDKEPI------- 476
Query: 421 QQAEDSEEDKKFLTGYDGIIHAELVVIDDEEEEDEGEAEK-PSYHPIAPHSQVYQPAKPT 479
+E+K + A L + E ++DE ++ P P Q + KP
Sbjct: 477 ----KGKEEK---------VPASLKEKEPETKKDEKMSKAGKEVKPKPPQLQGKKEEKPE 523
Query: 480 PLPRKRSEASPHENTNHKSPHKNSISLKEQEESLGSP 516
P +K ++ + E HK I E+ S G P
Sbjct: 524 PQIKKEAKPAISEKV---QIHKQDIVKPEKTVSHGKP 557
>gi|239735580 TRAF2 and NCK interacting kinase isoform 2 [Homo
sapiens]
Length = 1352
Score = 52.8 bits (125), Expect = 8e-07
Identities = 44/216 (20%), Positives = 105/216 (48%), Gaps = 23/216 (10%)
Query: 2 EEAELVKGRLQAITDKRKIQEEISQKRLKIEEDKLKHQHLKKKALREKWLL--------- 52
++ E + + Q + +++K EE ++R ++EE + + + L+K+ RE+
Sbjct: 376 QQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREE 435
Query: 53 DGISSGKEQEEMKKQNQQDQHQIQVLEQSILRLEKEIQDLEKAELQISTKEEAILKKLKS 112
+ + EQE +++Q +++Q Q+++L+Q +L + + + ++ +L+ + E + ++LK
Sbjct: 436 ERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQLEEQRQAERLQRQLKQ 495
Query: 113 IERTTEDIIRSVKVEREERAEESIEDIYANIPDLPKSYIPSRLRKEINEEKEDDEQNRKA 172
D + S++ +R+E+ + +Y + PS E +E NR++
Sbjct: 496 ----ERDYLVSLQHQRQEQRPVEKKPLY----HYKEGMSPSEKPAWAKEVEERSRLNRQS 547
Query: 173 LYAMEIKVEKDLKTGESTVLSSIPLPSDDFKGTGIK 208
AM KV + ++P S+ F +G++
Sbjct: 548 SPAMPHKVANRISD------PNLPPRSESFSISGVQ 577
Score = 40.4 bits (93), Expect = 0.004
Identities = 95/449 (21%), Positives = 177/449 (39%), Gaps = 75/449 (16%)
Query: 20 IQEEISQKRLKIEEDKLK-HQHLKKKALREKWLLDGISSGKEQEEMKKQNQQDQHQIQVL 78
I+++ ++++++I+ LK H KK EK + SG E+EE + + + + +
Sbjct: 289 IRDQPNERQVRIQ---LKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLP 345
Query: 79 EQSILRLEKEIQDLEKAELQISTKEEAILK-KLKSIERTTEDIIRSVKVEREERAEES-- 135
+S LR +D + +L + EA+ + +L+ +R E+ R + ER++R EE
Sbjct: 346 GESTLR-----RDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKE 400
Query: 136 ----IEDIYANIPDLPKSYIPSRLRKEINEEKEDDEQNRKALYAME-IKVEKDLKTGEST 190
+E+ +L K R+ E+ +E+ R+A + E I+ + + + +
Sbjct: 401 QRRRLEEQQRREKELRKQQ-EREQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLE 459
Query: 191 VLSSIPLPSD----DFKGTGIKVYDDG--------QKSVYAVSSNH----------SAAY 228
+L L ++K ++ Q+ Y VS H Y
Sbjct: 460 ILQQQLLHEQALLLEYKRKQLEEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLY 519
Query: 229 NGTDGLAPVEVEELLRQASERN----SKSPTEYHEPVYANPFYRPTTPQRET------VT 278
+ +G++P E ++ ER+ SP H+ AN P P R V
Sbjct: 520 HYKEGMSPSEKPAWAKEVEERSRLNRQSSPAMPHK--VANRISDPNLPPRSESFSISGVQ 577
Query: 279 PG----------PNFQERIKIKTNGLGIGVNESIHNM-GNGLS--EERGNNFNHISPIPP 325
P P + +K+ G + ++S+H GLS +E N +H
Sbjct: 578 PARTPPMLRPVDPQIPHLVAVKSQGPALTASQSVHEQPTKGLSGFQEALNVTSH-----R 632
Query: 326 VPHPRSVIQQAEEKLHTPQKRLMTPWEESNVMQDKDAPSPKPRLSPRETIFGKSEHQNSS 385
V PR E P R+ S + Q++D P P++ R T + + +S
Sbjct: 633 VEMPRQNSDPTSENPPLP-TRIEKFDRSSWLRQEEDIP---PKVPQRTTSISPALARKNS 688
Query: 386 P-TCQEDEEDVRYNIVHSLPPDINDTEPV 413
P + + + PD+ TEP+
Sbjct: 689 PGNGSALGPRLGSQPIRASNPDLRRTEPI 717
>gi|55741807 TRAF2 and NCK interacting kinase isoform 1 [Homo
sapiens]
Length = 1360
Score = 52.8 bits (125), Expect = 8e-07
Identities = 44/216 (20%), Positives = 105/216 (48%), Gaps = 23/216 (10%)
Query: 2 EEAELVKGRLQAITDKRKIQEEISQKRLKIEEDKLKHQHLKKKALREKWLL--------- 52
++ E + + Q + +++K EE ++R ++EE + + + L+K+ RE+
Sbjct: 376 QQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREE 435
Query: 53 DGISSGKEQEEMKKQNQQDQHQIQVLEQSILRLEKEIQDLEKAELQISTKEEAILKKLKS 112
+ + EQE +++Q +++Q Q+++L+Q +L + + + ++ +L+ + E + ++LK
Sbjct: 436 ERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQLEEQRQAERLQRQLKQ 495
Query: 113 IERTTEDIIRSVKVEREERAEESIEDIYANIPDLPKSYIPSRLRKEINEEKEDDEQNRKA 172
D + S++ +R+E+ + +Y + PS E +E NR++
Sbjct: 496 ----ERDYLVSLQHQRQEQRPVEKKPLY----HYKEGMSPSEKPAWAKEVEERSRLNRQS 547
Query: 173 LYAMEIKVEKDLKTGESTVLSSIPLPSDDFKGTGIK 208
AM KV + ++P S+ F +G++
Sbjct: 548 SPAMPHKVANRISD------PNLPPRSESFSISGVQ 577
Score = 40.4 bits (93), Expect = 0.004
Identities = 95/449 (21%), Positives = 177/449 (39%), Gaps = 75/449 (16%)
Query: 20 IQEEISQKRLKIEEDKLK-HQHLKKKALREKWLLDGISSGKEQEEMKKQNQQDQHQIQVL 78
I+++ ++++++I+ LK H KK EK + SG E+EE + + + + +
Sbjct: 289 IRDQPNERQVRIQ---LKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLP 345
Query: 79 EQSILRLEKEIQDLEKAELQISTKEEAILK-KLKSIERTTEDIIRSVKVEREERAEES-- 135
+S LR +D + +L + EA+ + +L+ +R E+ R + ER++R EE
Sbjct: 346 GESTLR-----RDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKE 400
Query: 136 ----IEDIYANIPDLPKSYIPSRLRKEINEEKEDDEQNRKALYAME-IKVEKDLKTGEST 190
+E+ +L K R+ E+ +E+ R+A + E I+ + + + +
Sbjct: 401 QRRRLEEQQRREKELRKQQ-EREQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLE 459
Query: 191 VLSSIPLPSD----DFKGTGIKVYDDG--------QKSVYAVSSNH----------SAAY 228
+L L ++K ++ Q+ Y VS H Y
Sbjct: 460 ILQQQLLHEQALLLEYKRKQLEEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLY 519
Query: 229 NGTDGLAPVEVEELLRQASERN----SKSPTEYHEPVYANPFYRPTTPQRET------VT 278
+ +G++P E ++ ER+ SP H+ AN P P R V
Sbjct: 520 HYKEGMSPSEKPAWAKEVEERSRLNRQSSPAMPHK--VANRISDPNLPPRSESFSISGVQ 577
Query: 279 PG----------PNFQERIKIKTNGLGIGVNESIHNM-GNGLS--EERGNNFNHISPIPP 325
P P + +K+ G + ++S+H GLS +E N +H
Sbjct: 578 PARTPPMLRPVDPQIPHLVAVKSQGPALTASQSVHEQPTKGLSGFQEALNVTSH-----R 632
Query: 326 VPHPRSVIQQAEEKLHTPQKRLMTPWEESNVMQDKDAPSPKPRLSPRETIFGKSEHQNSS 385
V PR E P R+ S + Q++D P P++ R T + + +S
Sbjct: 633 VEMPRQNSDPTSENPPLP-TRIEKFDRSSWLRQEEDIP---PKVPQRTTSISPALARKNS 688
Query: 386 P-TCQEDEEDVRYNIVHSLPPDINDTEPV 413
P + + + PD+ TEP+
Sbjct: 689 PGNGSALGPRLGSQPIRASNPDLRRTEPI 717
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 51.2 bits (121), Expect = 2e-06
Identities = 45/173 (26%), Positives = 85/173 (49%), Gaps = 18/173 (10%)
Query: 2 EEAELVKGRLQAITDKRKIQEEISQKRLKIEEDKLKHQHLKKKALREKWLLDGISSGKEQ 61
EE E ++ RL++ R+ QEE ++ LK EE+K Q +++ L+ + K +
Sbjct: 523 EEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKRE 582
Query: 62 EEMKKQNQQDQHQIQVLEQSILRLEKE-IQDLEKAELQISTKE------EAILKKLKSIE 114
EE ++Q + + Q + LEQ + R E E ++ E+ E ++ +E + +LK + E
Sbjct: 583 EE-RRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEE 641
Query: 115 RTTEDIIRSVKVEREERAEESIEDIYANIPDLPKSYIPSRLRKEINEEKEDDE 167
R + + R + RE+R + E+ + RL++E EE+ + E
Sbjct: 642 RRQQQLRREQQERREQRLKREEEE----------ERLEQRLKREHEEERREQE 684
Score = 49.7 bits (117), Expect = 7e-06
Identities = 50/213 (23%), Positives = 101/213 (47%), Gaps = 37/213 (17%)
Query: 11 LQAITDKRKIQEEISQK--RLKIEEDKLKHQH-------LKKKALREKWLLDGISSGKEQ 61
LQ ++R+ QE+ + R ++EE++ + +H L+++ +E+ LL ++
Sbjct: 856 LQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQR 915
Query: 62 EEMKKQNQQDQ-------HQIQVLEQSILRLEKEIQDLEKAELQ------ISTKEEAIL- 107
EE +K+ +Q+Q Q+Q E+ +LR E+E + ++ E Q + KEE +L
Sbjct: 916 EEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLG 975
Query: 108 ------------KKLKSIERTTEDIIRSVKVEREERAEESIEDIYANIPDLPKSYIPSRL 155
KK + E ++ + ++ ERE+R + E Y +L + +L
Sbjct: 976 EEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQE--EEQL 1033
Query: 156 RKEINEEKEDDEQNRKALYAMEIKVEKDLKTGE 188
+E E++ E+ R+ E++ E++ GE
Sbjct: 1034 LREEREKRRLQERERQYREEEELQQEEEQLLGE 1066
Score = 48.1 bits (113), Expect = 2e-05
Identities = 46/211 (21%), Positives = 101/211 (47%), Gaps = 30/211 (14%)
Query: 3 EAELVKGRLQAITDKRKIQEEISQKRLKIEEDKLKHQHLKKKALREKWLLDGISSGKEQE 62
E E + +L +++++++E ++RLK E+++ + Q LK++ R + L + ++
Sbjct: 541 EQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQ 600
Query: 63 EMKKQNQQDQHQIQVLEQSILRLEKE---IQDLEKAELQISTKEEAI-----------LK 108
+K++ + Q + EQ + R E E Q L K+E Q +++ + LK
Sbjct: 601 RLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLK 660
Query: 109 KLKSIERTTEDIIRSVKVER------EERAEESIEDIYANIP----------DLPKSYIP 152
+ + ER + + R + ER EE E++ E I + IP D +S +
Sbjct: 661 REEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVY 720
Query: 153 SRLRKEINEEKEDDEQNRKALYAMEIKVEKD 183
SR RK+ + + +++ ++ E++ +++
Sbjct: 721 SRPRKQEGQRRRQEQEEKRRRRESELQWQEE 751
Score = 47.4 bits (111), Expect = 3e-05
Identities = 49/199 (24%), Positives = 90/199 (45%), Gaps = 23/199 (11%)
Query: 2 EEAELVKGRLQAITDK---RKIQEEISQKRLKIEEDKL--KHQHLKKKALREKWLLDGIS 56
EE L +G Q + + RK +EE Q R + E K + Q L+++ L K+
Sbjct: 1672 EEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKF------ 1725
Query: 57 SGKEQEEMKKQNQQDQHQIQ-----VLEQSILRLEKEIQDLEKAELQISTKEEAILKKLK 111
+E+E+++++ +Q+Q + Q +LE+ LR E+E Q L + E +EE L+
Sbjct: 1726 --REEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLR--- 1780
Query: 112 SIERTTEDIIRSVKVEREERAEESIEDIYANIPDLPKSYIPSRLRKEINEEKEDDEQNRK 171
+ E +RS + +R+ R EE + P+ +E + E+ EQ +
Sbjct: 1781 --QEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLR 1838
Query: 172 ALYAMEIKVEKDLKTGEST 190
+ + E+ T E +
Sbjct: 1839 QERDRQYRAEEQFATQEKS 1857
Score = 46.2 bits (108), Expect = 8e-05
Identities = 40/165 (24%), Positives = 84/165 (50%), Gaps = 12/165 (7%)
Query: 10 RLQAITDKRKIQEEISQKRLKIEEDKLKHQHLKKKALREKWLLDGISSGKEQEEMKKQNQ 69
R + + +RK +EE Q+R + ++ + + K+ RE L KE+E+++++
Sbjct: 212 RRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLR------KEEEKLQEEEP 265
Query: 70 QDQHQIQVLEQSILRLEKEIQDLEKAELQISTKEEAILKKLKSIERTTEDIIRSVKVER- 128
Q Q ++Q E+ + +LE+ Q+L + E Q +++ L++ + + R E+ R + ER
Sbjct: 266 QRQRELQEEEEQLRKLER--QELRR-ERQEEEQQQQRLRREQQLRRKQEEERREQQEERR 322
Query: 129 --EERAEESIEDIYANIPDLPKSYIPSRLRKEINEEKEDDEQNRK 171
+ER E+ E + + +LR+E EE+ + + R+
Sbjct: 323 EQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRRE 367
Score = 44.3 bits (103), Expect = 3e-04
Identities = 43/200 (21%), Positives = 100/200 (50%), Gaps = 22/200 (11%)
Query: 2 EEAELVKGRLQAITDKRKIQEEISQKRLKIEEDKLKHQHLKKKALREKW---LLDGISSG 58
+E E + L+ ++R+ Q+E +++L+ E+++ + Q LK++ E+ L
Sbjct: 480 QEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLR 539
Query: 59 KEQEEMK----KQNQQDQHQIQVLEQSILRLEKEIQDL------EKAELQISTKEEAILK 108
+EQEE + K+ ++ + + + EQ + R ++E +D E+ + ++ ++E L+
Sbjct: 540 REQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLE 599
Query: 109 ---KLKSIERTTEDIIRSVKVEREERAEESIEDIYANIPDLPKSYIPSRLRKEINEEKED 165
K + +ER ++ R +++REE EE + + L R ++++ E+++
Sbjct: 600 QRLKREEVERLEQEERREQRLKREEPEEERRQQL------LKSEEQEERRQQQLRREQQE 653
Query: 166 DEQNRKALYAMEIKVEKDLK 185
+ R E ++E+ LK
Sbjct: 654 RREQRLKREEEEERLEQRLK 673
Score = 43.1 bits (100), Expect = 7e-04
Identities = 37/159 (23%), Positives = 83/159 (52%), Gaps = 14/159 (8%)
Query: 16 DKRKIQEEISQKRLKIEEDKLKHQHLKKKALREKWLLDGISSGKEQEEMKKQNQQDQHQI 75
+KR++QE Q R EE++L+ + E+ LL + ++E+++Q ++++ ++
Sbjct: 1039 EKRRLQERERQYR---EEEELQQE--------EEQLLGEERETRRRQELERQYRKEE-EL 1086
Query: 76 QVLEQSILRLEKEIQDLEKAELQISTKEEAILKKLKSIERTTEDIIRSVKVEREERAEES 135
Q E+ +LR E E + ++ E Q +EE + ++ + + R + R ++ER+ R EE
Sbjct: 1087 QQEEEQLLREEPEKRRRQERERQCREEEE-LQQEEEQLLREEREKRRRQELERQYREEEE 1145
Query: 136 IEDIYANI-PDLPKSYIPSRLRKEINEEKEDDEQNRKAL 173
++ + + P+ L ++ EE+E ++ + L
Sbjct: 1146 VQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLL 1184
Score = 42.4 bits (98), Expect = 0.001
Identities = 45/216 (20%), Positives = 104/216 (48%), Gaps = 28/216 (12%)
Query: 1 MEEAELVKGRLQAITDKRKIQEEISQKR---LKIEEDKLKHQHLKKKALREKWLLDGISS 57
++ E K R Q + + +E++ Q+ L+ E +K + Q +++ ++K L
Sbjct: 913 LQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQ 972
Query: 58 --GKEQEEMKKQNQQ----DQHQIQVLEQSILRLEKEIQDLEKAELQISTKEEAILKKLK 111
G+E E+ ++Q ++ ++ ++Q E+ +LR E+E + ++ E Q K+E + ++ +
Sbjct: 973 LLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDE-LQQEEE 1031
Query: 112 SIERTTEDIIRSVKVEREERAEESIEDIYANI----------PDLPKSYIPSRLRKEINE 161
+ R + R + ER+ R EE ++ + +L + Y R +E+ +
Sbjct: 1032 QLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQY---RKEEELQQ 1088
Query: 162 E-----KEDDEQNRKALYAMEIKVEKDLKTGESTVL 192
E +E+ E+ R+ + + E++L+ E +L
Sbjct: 1089 EEEQLLREEPEKRRRQERERQCREEEELQQEEEQLL 1124
Score = 40.4 bits (93), Expect = 0.004
Identities = 40/187 (21%), Positives = 86/187 (45%), Gaps = 22/187 (11%)
Query: 2 EEAELVKGRLQAITDKRKIQEEISQKRLKIEEDKLKHQHLKKKAL--REKWLLDGISSGK 59
+E E + +L+ R+ Q+ +++L+ E+ + Q L+++ RE+ L +
Sbjct: 368 QEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRR 427
Query: 60 EQEEMKKQNQQDQHQIQVLEQSILRLEKEIQDLEKAELQISTKEEAILKKLKSIERTTED 119
EQEE + + +H+ + EQ + R ++E +D K E + E+ K+ ++ E
Sbjct: 428 EQEE---ERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEER 484
Query: 120 IIRSVKVEREERAEESIEDIYANIPDLPKSYIPSRLRKEINEEKEDDEQNRKALYAMEIK 179
R +K+E EER E+ R +++ E+E+ + R E +
Sbjct: 485 RERWLKLEEEERREQQ-----------------ERREQQLRREQEERREQRLKRQEEEER 527
Query: 180 VEKDLKT 186
+++ L++
Sbjct: 528 LQQRLRS 534
Score = 37.7 bits (86), Expect = 0.028
Identities = 33/131 (25%), Positives = 67/131 (51%), Gaps = 17/131 (12%)
Query: 2 EEAELVKGRLQAITDKRKIQE-EISQKRLKIEEDKLKHQHLKKKALREKWLLDGISSGKE 60
EE +L K Q + +R+ QE E Q+RL+ + Q L++K E+ ++
Sbjct: 274 EEEQLRKLERQEL--RRERQEEEQQQQRLR------REQQLRRKQEEER--------REQ 317
Query: 61 QEEMKKQNQQDQHQIQVLEQSILRLEKEIQDLEKAELQISTKEEAILKKLKSIERTTEDI 120
QEE ++Q ++ + Q + EQ + R ++E ++ + Q + E L++ + ER + +
Sbjct: 318 QEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQL 377
Query: 121 IRSVKVEREER 131
R ++ RE++
Sbjct: 378 RREQQLRREQQ 388
Score = 36.2 bits (82), Expect = 0.080
Identities = 42/184 (22%), Positives = 89/184 (48%), Gaps = 24/184 (13%)
Query: 17 KRKIQEEISQKRLKIEEDKLKHQHLKKKALREKWLLDGISSGKEQEEMKKQNQQDQHQIQ 76
++K ++E ++RLK E+++ + LK++ E+ EQE K+Q ++DQ + +
Sbjct: 435 EQKHEQERREQRLKREQEE-RRDWLKREEETER---------HEQERRKQQLKRDQEEER 484
Query: 77 VLEQSILRLEKEIQDLEKAELQI----STKEEAILKKLKSIERTTEDI--IRSVKVEREE 130
L E+ + E+ E Q+ + E LK+ + ER + + + ++ E+EE
Sbjct: 485 RERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEE 544
Query: 131 RAEESIEDIYANIPDLPKSYIPSRLRKEINE------EKEDDEQNRKALYAMEIKVEKDL 184
R E+ ++ L + RL++E E ++E++ + ++ E ++E+ L
Sbjct: 545 RREQLLK--REEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRL 602
Query: 185 KTGE 188
K E
Sbjct: 603 KREE 606
Score = 36.2 bits (82), Expect = 0.080
Identities = 31/137 (22%), Positives = 66/137 (48%), Gaps = 11/137 (8%)
Query: 10 RLQAITDKRKIQEEISQKR---LKIEEDKLKHQHLKKKALREKWLLDGISSGKEQEEMKK 66
R Q + + + +EE+ Q+ L+ E +K + Q +++ E+ L +E K+
Sbjct: 1072 RRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKR 1131
Query: 67 QNQQ------DQHQIQVLEQSILRLEKEIQDLEKAELQISTKEEAILKKLKSIERTTEDI 120
+ Q+ ++ ++Q E+ +LR E E + ++ E Q +EE ++ + + E
Sbjct: 1132 RRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEK- 1190
Query: 121 IRSVKVEREERAEESIE 137
R + ER+ R EE ++
Sbjct: 1191 -RRQERERQYREEEELQ 1206
Score = 35.4 bits (80), Expect = 0.14
Identities = 42/214 (19%), Positives = 89/214 (41%), Gaps = 39/214 (18%)
Query: 18 RKIQEEISQ-------KRLKIEEDKLKHQHLKKKALREKWLL--DGISSGKEQEEMKKQN 68
RK +EE Q ++ + EE +++ Q ++K L E+ L + +E+E++ ++
Sbjct: 1414 RKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQER 1473
Query: 69 QQDQHQIQVLEQSILRLEKEIQDLEK------AELQISTKEEAILKKLKSIER------- 115
++ Q Q ++ L E++++ E+ EL+ E L++ + + R
Sbjct: 1474 EEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKF 1533
Query: 116 ---------------TTEDIIRSVKVEREERAEESIEDIYANIPDLPKSYIPSRLRKEIN 160
+D R + E + R E + + D ++R++
Sbjct: 1534 LQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQ 1593
Query: 161 EEK--EDDEQNRKALYAMEIKVEKDLKTGESTVL 192
E K ED++Q R+ +++ E+D K E L
Sbjct: 1594 ERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQL 1627
Score = 34.3 bits (77), Expect = 0.30
Identities = 37/186 (19%), Positives = 84/186 (45%), Gaps = 22/186 (11%)
Query: 9 GRLQAITDKRKIQEEISQKRLKIEEDKLKHQHLKKKALREKWLLDGISSGKEQEEMKKQN 68
G+ + D+R +E Q+R + + +L+ + +++ + + ++ G+EQ E KQ
Sbjct: 105 GKESLLQDRR---QEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSE--KQE 159
Query: 69 QQDQHQIQVLEQSILRLEKEIQDLEKAELQISTKEEAILKKLKSIE------------RT 116
+ +Q Q ++ + R +E Q+ E+ EE L+ K E R
Sbjct: 160 RLEQRDRQRRDEELWRQRQEWQEREERR-----AEEEQLQSCKGHETEEFPDEEQLRRRE 214
Query: 117 TEDIIRSVKVEREERAEESIEDIYANIPDLPKSYIPSRLRKEINEEKEDDEQNRKALYAM 176
++ R + E++++ E + ++ + + LRKE + +E++ Q ++ L
Sbjct: 215 LLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEE 274
Query: 177 EIKVEK 182
E ++ K
Sbjct: 275 EEQLRK 280
Score = 33.9 bits (76), Expect = 0.40
Identities = 29/161 (18%), Positives = 81/161 (50%), Gaps = 10/161 (6%)
Query: 14 ITDKRKIQEEISQKRLKIEEDKLKHQHL--KKKALREKWLLDGISSGKEQEEMKKQNQQD 71
+ +++++ + Q++ EE +L+ Q +++ R++ + +E+EE + Q+
Sbjct: 1518 LEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQER 1577
Query: 72 QHQIQVLEQSILRLEKEIQDLE-KAELQISTKEEAILKKLKSIERTTEDIIR---SVKVE 127
+ ++ EQ + R E+E + +E + +L+ ++ + ++ R E +++ ++
Sbjct: 1578 DRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLH 1637
Query: 128 REERAEESIEDIYANIPDLPKSYIPSRLRKEINEEKEDDEQ 168
R+ER + +E+ P L + +LR + + + ++EQ
Sbjct: 1638 RQERDRKFLEE----EPQLRRQEREQQLRHDRDRKFREEEQ 1674
Score = 33.5 bits (75), Expect = 0.52
Identities = 40/203 (19%), Positives = 92/203 (45%), Gaps = 23/203 (11%)
Query: 2 EEAELVKGRLQAITDKRKIQEEISQKRLKIEEDK----------------LKHQHLKKKA 45
E+ E + ++ +K+ ++EE +KR + E D+ L+ Q +K
Sbjct: 1303 EQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRK- 1361
Query: 46 LREKWLLDGISSGKEQEEMKKQNQQDQHQIQVLEQSILRLEKEIQDLEKAELQISTKEEA 105
RE+ L K EE ++ +Q++ + + E+ LR ++ Q L + + +EE
Sbjct: 1362 FREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQ 1421
Query: 106 ILKKLKSIERTTEDIIRSVKVEREERAEESIEDIYANIPDLPKSYIPSRLRKEINEEKED 165
L + + + E+ +V R+ER + +E+ + + + R +++ +E+E+
Sbjct: 1422 QLSRQERDRKFREE---EQQVRRQERERKFLEEEQQLRQERHRKF---REEEQLLQEREE 1475
Query: 166 DEQNRKALYAMEIKVEKDLKTGE 188
+ +R+ ++ E+ L+ E
Sbjct: 1476 QQLHRQERDRKFLEEEQQLRRQE 1498
Score = 33.1 bits (74), Expect = 0.68
Identities = 46/177 (25%), Positives = 78/177 (44%), Gaps = 29/177 (16%)
Query: 5 ELVKGRLQAITDKRKIQEEISQKR---LKIEEDKLKHQHLKKKALREKWLLDGISSGKEQ 61
E K R Q + + + +EE+ Q+ L+ E +K + Q L+++ +E+
Sbjct: 1127 EREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQY-------------REE 1173
Query: 62 EEMKKQNQQDQHQIQVLEQSILRLEKEIQDLEKAELQIST-----KEEAILKKLK-SIER 115
EE+ QQ++ Q+ EQ R E+E Q E+ ELQ ++E LK E
Sbjct: 1174 EEL----QQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEP 1229
Query: 116 TTEDIIRSVKVEREERAEESIEDIYANIPDLPKSYIPSRLRKEINEEKE-DDEQNRK 171
E+ +R KV + R E + + L L+ + E++E D EQ R+
Sbjct: 1230 EKENAVRDNKVYCKGRENEQFRQLEDS--QLRDRQSQQDLQHLLGEQQERDREQERR 1284
Score = 32.7 bits (73), Expect = 0.89
Identities = 36/157 (22%), Positives = 76/157 (48%), Gaps = 12/157 (7%)
Query: 18 RKIQEEISQKRLKIEEDKLKHQHLKKKALREKWLLDGISSGKEQEEMKKQNQQDQHQIQV 77
RK +EE Q R + EE +L Q +K E+ + ++E +++ +D+ Q++
Sbjct: 1555 RKFREE-EQLRQEREEQQLSRQERDRKFRLEEQKV-------RRQEQERKFMEDEQQLRR 1606
Query: 78 LE-QSILRLEKEIQDLEKAELQISTKEEAILKKLKSIERTTEDIIRSVKVEREERAEESI 136
E Q LR E++ + E +L + +EE L + + + E+ + + ERE++
Sbjct: 1607 QEGQQQLRQERDRKFREDEQL-LQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDR 1665
Query: 137 EDIYANIPDLPKSYIPSRLRKEINEEK--EDDEQNRK 171
+ + L + +LR++ + K E+++Q R+
Sbjct: 1666 DRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRR 1702
Score = 32.3 bits (72), Expect = 1.2
Identities = 40/195 (20%), Positives = 89/195 (45%), Gaps = 27/195 (13%)
Query: 2 EEAELVKGRLQAITDKRKIQEEISQKRLKIEEDKLKHQHLKKKA--LREKWLLDGISSGK 59
+E E + RL+ R+ QEE +R + +E++ + Q +++ RE+ L +
Sbjct: 291 QEEEQQQQRLRREQQLRRKQEE---ERREQQEERREQQERREQQEERREQQLRREQEERR 347
Query: 60 EQEEMKKQNQQDQHQIQVLEQSILRLEKEIQDLEKAELQISTKEEAILKKLKSIERTTED 119
EQ+ ++Q ++ + Q EQ R E++++ ++ + + E L++ + + R +
Sbjct: 348 EQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRR-EQQ 406
Query: 120 IIRSVKVEREERAEESIEDIYANIPDLPKSYIPSRLRKEINEEKED---DEQNRKALYAM 176
+ R ++ RE++ +LR+E EE+ + +++ R+
Sbjct: 407 LRREQQLRREQQLRRE-----------------QQLRREQEEERHEQKHEQERREQRLKR 449
Query: 177 EIKVEKD-LKTGEST 190
E + +D LK E T
Sbjct: 450 EQEERRDWLKREEET 464
Score = 32.0 bits (71), Expect = 1.5
Identities = 46/207 (22%), Positives = 90/207 (43%), Gaps = 41/207 (19%)
Query: 18 RKIQEEISQKRLKIEEDKLK-HQHLKKKALREK-------------------------WL 51
R+ Q+E ++RLK EE++ + Q LK++ E+ W
Sbjct: 648 RREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQ 707
Query: 52 LDGISSGKEQEEMKK-QNQQDQHQIQVLEQSILRLEKEI--QDLEKAELQISTKE----- 103
L+ + ++ + + + Q+ Q + Q E+ R E E+ Q+ E+A Q +E
Sbjct: 708 LESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDF 767
Query: 104 ----EAILKKLKSIERTTEDIIRSVKVEREERAEESIEDIYANIPDLPKSYIPSRLRKEI 159
+A K + +R + + ER+ RAEE + +P+ + R R+E
Sbjct: 768 TWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRRER 827
Query: 160 NEE---KEDDEQNRKALYAMEIKVEKD 183
+E E++EQ ++ A +++ E+D
Sbjct: 828 EKELQFLEEEEQLQRRERAQQLQEEED 854
Score = 31.2 bits (69), Expect = 2.6
Identities = 37/167 (22%), Positives = 74/167 (44%), Gaps = 10/167 (5%)
Query: 17 KRKIQEEISQKRLKIEEDKLKHQHLKKKALREKWLLDGISSGKEQEEMKKQNQQDQHQIQ 76
++ ++EE +R + E LK + + RE+ L +EE + Q+ + +
Sbjct: 1374 RKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFR 1433
Query: 77 VLEQSILRLEKEIQDLEKAELQISTKEEAILKKLKSI--ERTTEDIIRSVK----VEREE 130
EQ + R E+E + LE+ E Q+ + ++ + + ER + + R + +E E+
Sbjct: 1434 EEEQQVRRQERERKFLEE-EQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQ 1492
Query: 131 RAEESIEDIYANIPDLPKSYIPSRLRKEINEEKEDDEQNRKALYAME 177
+ D +L +S P RK + EE++ Q R+ + E
Sbjct: 1493 QLRRQERDRKFREQEL-RSQEPE--RKFLEEEQQLHRQQRQRKFLQE 1536
Score = 31.2 bits (69), Expect = 2.6
Identities = 37/176 (21%), Positives = 77/176 (43%), Gaps = 21/176 (11%)
Query: 16 DKRKIQEEISQKRLKIEEDK-----------LKHQHLKKKALREKWLLDGISSGKEQEEM 64
D+++++ + Q++L+ E D+ + Q L ++ K+L + +++ E
Sbjct: 1600 DEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQ 1659
Query: 65 KKQNQQDQHQIQVLEQSILRLEKEIQDLEKAELQISTKEEAILKKLKSIER---TTEDII 121
+ ++ +D+ + E+ L E E Q L + E +EE + + ER E +
Sbjct: 1660 QLRHDRDR---KFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQL 1716
Query: 122 RSVKVEREERAEESIEDIYANIPDLPKSYIPSRLRKEINEEKEDDEQNRKALYAME 177
R ++ER+ R EE + + + R RK + EE+ E+ + L E
Sbjct: 1717 RRQELERKFREEEQLR----QETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQE 1768
>gi|94538359 golgi autoantigen, golgin subfamily a, 6B [Homo
sapiens]
Length = 693
Score = 49.7 bits (117), Expect = 7e-06
Identities = 45/203 (22%), Positives = 107/203 (52%), Gaps = 15/203 (7%)
Query: 2 EEAELVKGRLQAITDKRKIQEEISQK---RLKIEEDKLKHQHLKKKALREKWLLDGISSG 58
+E E ++G+LQ+ + + +S++ RL+ +E+ L+ Q +++ +E+
Sbjct: 309 QEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEVQRVREQERLCEQNERLR 368
Query: 59 KEQEEMKKQNQQDQHQIQVLEQSILRLEKEIQDLEKAELQISTKEEAILKKLKSIERTTE 118
++Q+ +++Q ++ + Q Q L + RL KE + L+K E ++ +EE + KK + +++ E
Sbjct: 369 EQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEE 428
Query: 119 DIIRSVKVEREERAEESIEDIYANIPDLPKSYIPSRLRKEINEEKED-DEQNRKALYAME 177
+ S + +++ E + + ++ + KS + +L +++ E +E DE++ +A
Sbjct: 429 RLALSQNHKLDKQLAEP-QCSFEDLNNEKKSAL--QLEQQVKELQEKLDEEHLEAASQQN 485
Query: 178 IKVEKDLKTGESTVLSSIPLPSD 200
++E T LS + LP +
Sbjct: 486 QQLE--------TQLSLVALPGE 500
>gi|148839339 nexilin (F actin binding protein) [Homo sapiens]
Length = 675
Score = 48.9 bits (115), Expect = 1e-05
Identities = 67/290 (23%), Positives = 114/290 (39%), Gaps = 51/290 (17%)
Query: 16 DKRKIQEEISQKRLKIEEDKLKHQHLKKKALREKWLLDGISSGKEQEEMKKQNQQDQHQI 75
D K +EE ++R+K EEDK ++ +L+E L + + + E KK++
Sbjct: 191 DLEKEREE--KERIKYEEDKRIRYEEQRPSLKEAKCLSLVMDDEIESEAKKES------- 241
Query: 76 QVLEQSILRLEKEIQDLEKAELQISTKEEAILKKLKSIERTTEDIIRSVKVEREERAEES 135
L L+L E + ++ E + EE K+L+ +R E+ R + E EE + +
Sbjct: 242 --LSPGKLKLTFEELERQRQENRKKQAEEEARKRLEEEKRAFEEARRQMVNEDEENQDTA 299
Query: 136 IEDIYANIPDLPKSYIPSRLR---KEINEEKEDDEQNRKALYAMEIKVEKDLKTGESTVL 192
+ K Y P +L+ +E+ ++ +DE+ RKA ++E++ K
Sbjct: 300 ---------KIFKGYRPGKLKLSFEEMERQRREDEK-RKAEEEARRRIEEEKKAFAEARR 349
Query: 193 SSIPLPSDDFKGTGIKVYDDGQKSVYAVSSNHSAAYNGTDGLAPVEVEELLRQ------- 245
+ V DD +Y S T G + EELL+Q
Sbjct: 350 N--------------MVVDDDSPEMYKTISQEFL----TPGKLEINFEELLKQKMEEEKR 391
Query: 246 --ASERNSKSPTEYHEPVYANPFYRPTTPQRETVTPGPNFQERIKIKTNG 293
ER K E E + ET ++E IK+K +G
Sbjct: 392 RTEEERKHKLEMEKQEFEQLRQEMGEEEEENETFGLSREYEELIKLKRSG 441
Score = 36.2 bits (82), Expect = 0.080
Identities = 45/203 (22%), Positives = 98/203 (48%), Gaps = 52/203 (25%)
Query: 7 VKGRLQAITDKRKIQEEISQKRLKIEEDKLKHQHLKKKA--LREKWLLDGISSGKEQE-- 62
VK + +A+ ++ +EE +Q+R + E+ + K Q+++++ R++ + + ++S E++
Sbjct: 31 VKDKFEAM---QRAREERNQRRSRDEKQRRKEQYIREREWNRRKQEIKEMLASDDEEDVS 87
Query: 63 --------------------EMKKQNQQDQHQIQVLEQSILRLEKEIQDLEKAELQISTK 102
EM+KQ Q++Q + + E+ R+E+++ + K + +++ +
Sbjct: 88 SKVEKAYVPKLTGTVKGRFAEMEKQRQEEQRK-RTEEERKRRIEQDMLEKRKIQRELAKR 146
Query: 103 EEAILKKLKSIERTTEDIIRSVKVEREERAEESIEDIYANIPDLPKSYIPS-RLRKEINE 161
E I EDI + E ++S+ + +P KSY S +++K +
Sbjct: 147 AEQI-----------EDINNTGTESASEEGDDSL--LITVVP--VKSYKTSGKMKKNFED 191
Query: 162 -EKEDDEQNRKALYAMEIKVEKD 183
EKE +E+ R IK E+D
Sbjct: 192 LEKEREEKER-------IKYEED 207
Score = 29.6 bits (65), Expect = 7.5
Identities = 26/129 (20%), Positives = 51/129 (39%), Gaps = 8/129 (6%)
Query: 307 NGLSEERGNNFNHISPIPPVPHPRSVIQQAEEKLHTPQKRLMTPWEESNVMQDKDAPSPK 366
N +S++ + P+P P+ ++K Q+ EE N + +D +
Sbjct: 2 NDISQKAEILLSSSKPVPKTYVPKLGKGDVKDKFEAMQRAR----EERNQRRSRDEKQRR 57
Query: 367 PRLSPRETIFGKSEHQNSSPTCQEDEEDVRYNIVHSLPPDINDTEPVTMIFMGYQQAED- 425
RE + + + + +DEEDV + + P + T M Q+ E+
Sbjct: 58 KEQYIREREWNRRKQEIKEMLASDDEEDVSSKVEKAYVPKLTGTVKGRFAEMEKQRQEEQ 117
Query: 426 ---SEEDKK 431
+EE++K
Sbjct: 118 RKRTEEERK 126
Score = 29.3 bits (64), Expect = 9.8
Identities = 26/105 (24%), Positives = 57/105 (54%), Gaps = 11/105 (10%)
Query: 9 GRLQAITDKRKIQEEISQKR---LKIEEDKLKHQH------LKKKALREKWLLDGISSGK 59
G+L ++KI+EE +++R L+I+E + ++ H ++ E ++
Sbjct: 456 GQLSEKEIQKKIEEERARRRAIDLEIKEREAENFHEEDDVDVRPARKSEAPFTHKVNMKA 515
Query: 60 EQEEMKKQNQQDQHQIQVLEQSILRLEKEIQDLEKAELQISTKEE 104
E+M K ++++ Q ++ EQ +LR++ E ++++ A LQ +EE
Sbjct: 516 RFEQMAKAREEEE-QRRIEEQKLLRMQFEQREID-AALQKKREEE 558
>gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo
sapiens]
Length = 693
Score = 48.5 bits (114), Expect = 2e-05
Identities = 45/203 (22%), Positives = 106/203 (52%), Gaps = 15/203 (7%)
Query: 2 EEAELVKGRLQAITDKRKIQEEISQK---RLKIEEDKLKHQHLKKKALREKWLLDGISSG 58
+E E ++G+LQ+ + + +S++ RL+ +E+ L+ Q ++ +E+
Sbjct: 309 QEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLR 368
Query: 59 KEQEEMKKQNQQDQHQIQVLEQSILRLEKEIQDLEKAELQISTKEEAILKKLKSIERTTE 118
++Q+ +++Q ++ + Q Q L + RL KE + L+K E ++ +EE + KK + +++ E
Sbjct: 369 EQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEE 428
Query: 119 DIIRSVKVEREERAEESIEDIYANIPDLPKSYIPSRLRKEINEEKED-DEQNRKALYAME 177
+ S + +++ E + + ++ + KS + +L +++ E +E DE++ +A
Sbjct: 429 RLALSQNHKLDKQLAEP-QCSFEDLNNEKKSAL--QLEQQVKELQEKLDEEHLEAASQRN 485
Query: 178 IKVEKDLKTGESTVLSSIPLPSD 200
++E T LS + LP +
Sbjct: 486 QQLE--------TQLSLVALPGE 500
>gi|51472437 PREDICTED: golgi autoantigen, golgin subfamily a, 6C
isoform 1 [Homo sapiens]
Length = 693
Score = 48.5 bits (114), Expect = 2e-05
Identities = 45/203 (22%), Positives = 106/203 (52%), Gaps = 15/203 (7%)
Query: 2 EEAELVKGRLQAITDKRKIQEEISQK---RLKIEEDKLKHQHLKKKALREKWLLDGISSG 58
+E E ++G+LQ+ + + +S++ RL+ +E+ L+ Q ++ +E+
Sbjct: 309 QEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLR 368
Query: 59 KEQEEMKKQNQQDQHQIQVLEQSILRLEKEIQDLEKAELQISTKEEAILKKLKSIERTTE 118
++Q+ +++Q ++ + Q Q L + RL KE + L+K E ++ +EE + KK + +++ E
Sbjct: 369 EQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEE 428
Query: 119 DIIRSVKVEREERAEESIEDIYANIPDLPKSYIPSRLRKEINEEKED-DEQNRKALYAME 177
+ S + +++ E + + ++ + KS + +L +++ E +E DE++ +A
Sbjct: 429 RLALSQNHKLDKQLAEP-QCSFEDLNNEKKSAL--QLEQQVKELQEKLDEEHLEAASQRN 485
Query: 178 IKVEKDLKTGESTVLSSIPLPSD 200
++E T LS + LP +
Sbjct: 486 QQLE--------TQLSLVALPGE 500
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 48.5 bits (114), Expect = 2e-05
Identities = 47/222 (21%), Positives = 100/222 (45%), Gaps = 38/222 (17%)
Query: 3 EAELVKGRLQAITDKRKIQEEISQKRLKIEEDKLKHQHLKKKALREKWLLDGISSGKEQE 62
EAE + +A++ R ++E + K ++ + Q+ + +A E + GK
Sbjct: 1475 EAEAREKETKALSLARALEEALEAK------EEFERQNKQLRADMEDLMSSKDDVGKNVH 1528
Query: 63 EMKKQNQQDQHQIQVLEQSILRLEKEIQDLEKAELQIST--------------------- 101
E++K + + Q++ + + LE E+Q E A+L++
Sbjct: 1529 ELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNE 1588
Query: 102 -KEEAILKKLKSIERTTED--IIRSVKVEREERAEESIEDIYANIPDLPKS--YIPSRLR 156
K+ ++K+++ +E ED R++ V +++ E ++D+ A I K+ + +LR
Sbjct: 1589 EKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLR 1648
Query: 157 ------KEINEEKEDDEQNRKALYAMEIKVEKDLKTGESTVL 192
K+ E E+ +R ++A + EK LK+ E+ +L
Sbjct: 1649 KLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEIL 1690
Score = 40.0 bits (92), Expect = 0.006
Identities = 41/199 (20%), Positives = 93/199 (46%), Gaps = 37/199 (18%)
Query: 9 GRLQAITDKRKIQEEISQKRLKIEEDKLKHQHLKKKALREKWLLDGIS------------ 56
G+ + +KR+++ I+Q ++EE++ + L + + +D ++
Sbjct: 1723 GKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQK 1782
Query: 57 SGKEQEEMKKQNQQDQHQIQVLE--------QSILRLEKEIQDLEKAELQISTKEEAILK 108
S ++++++QN++ + ++Q LE +I LE +I LE+ +L+ KE A
Sbjct: 1783 SDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEE-QLEQEAKERAAAN 1841
Query: 109 KL-KSIERTTEDIIRSVKVERE--ERAEESIEDIYANIPDLPKSYIPSRLRKEINEEKED 165
KL + E+ ++I V+ ER ++ +E +E A + K++ + E+
Sbjct: 1842 KLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARM-------------KQLKRQLEE 1888
Query: 166 DEQNRKALYAMEIKVEKDL 184
E+ A K++++L
Sbjct: 1889 AEEEATRANASRRKLQREL 1907
Score = 39.7 bits (91), Expect = 0.007
Identities = 42/205 (20%), Positives = 95/205 (46%), Gaps = 25/205 (12%)
Query: 2 EEAELVKGRLQAITDKRKIQEEISQKRLKIEEDKLKHQHLKKKALREKWLLDGISSGKEQ 61
EE K +L+ +T + KI++ + ++ L +E+ K +K+K L E + + S E+
Sbjct: 962 EEGARQKLQLEKVTAEAKIKK-MEEEILLLEDQNSKF--IKEKKLMEDRIAECSSQLAEE 1018
Query: 62 EEMKKQ----NQQDQHQIQVLEQSILRLEKEIQDLEKAELQISTKEEAILKKLKSIERTT 117
EE K + + I LE+ + + EK Q+LEKA+ ++ + + ++ ++
Sbjct: 1019 EEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQI 1078
Query: 118 EDIIRSVKVEREE----------------RAEESIEDIYANIPDLPKSYIPSRLRKEINE 161
+++ + + EE A + + ++ A I +L + + + + E
Sbjct: 1079 DELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAE 1138
Query: 162 EKEDDEQNRKALYAMEIKVEKDLKT 186
+++ D + L A++ ++E L T
Sbjct: 1139 KQKRDLS--EELEALKTELEDTLDT 1161
Score = 38.9 bits (89), Expect = 0.012
Identities = 39/169 (23%), Positives = 83/169 (49%), Gaps = 14/169 (8%)
Query: 3 EAELVKGRLQAITDKRKIQEEISQKRLKIEEDKLKHQHLKKKALREKWLLDGISSGKEQE 62
EAE ++ RL A K++++E + ++EE++ ++Q L+ + + + + + ++E
Sbjct: 905 EAEEMRARLAA--KKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEE 962
Query: 63 EMKKQNQQDQHQIQVLEQSILRLEKEIQDLEKAELQISTKEEAILKKLKSIERTTEDIIR 122
E +Q Q LE+ + E +I+ +E+ L + + +K+ K +E +
Sbjct: 963 EGARQKLQ-------LEK--VTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAE-CS 1012
Query: 123 SVKVEREERAEESIEDIYANIPDLPKSYIPSRLRKEINEEKEDDEQNRK 171
S E EE+A+ + N ++ S + RL+KE +E ++ RK
Sbjct: 1013 SQLAEEEEKAKNLAK--IRNKQEVMISDLEERLKKEEKTRQELEKAKRK 1059
Score = 38.9 bits (89), Expect = 0.012
Identities = 55/260 (21%), Positives = 110/260 (42%), Gaps = 28/260 (10%)
Query: 9 GRLQAITD-KRKIQEEISQKRLKIEEDKLKHQHLKKKALREKWLLDGISSGKEQEEMKKQ 67
G ++++ + K+K+ ++ ++EE L + L+K R + LD ++ + +
Sbjct: 1385 GTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVAS 1444
Query: 68 N----QQDQHQIQVLEQSILRLEKEIQDLEKAELQISTKEEAILKKLKSIERTTEDIIRS 123
N Q+ Q+ E+SI E +D +AE + KE L +++E E
Sbjct: 1445 NLEKKQKKFDQLLAEEKSISARYAEERD--RAEAEAREKETKALSLARALEEALEAKEEF 1502
Query: 124 VKVEREERAE-----ESIEDIYANIPDLPKSYIPSRLRKEIN------EEKEDDEQNRK- 171
+ ++ RA+ S +D+ N+ +L KS L +++ EE ED+ Q +
Sbjct: 1503 ERQNKQLRADMEDLMSSKDDVGKNVHELEKS--KRALEQQVEEMRTQLEELEDELQATED 1560
Query: 172 -------ALYAMEIKVEKDLKTGESTVLSSIPLPSDDFKGTGIKVYDDGQKSVYAVSSNH 224
+ AM+ + E+DL+T + L + ++ D+ ++ AV+S
Sbjct: 1561 AKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKK 1620
Query: 225 SAAYNGTDGLAPVEVEELLR 244
+ D A +E R
Sbjct: 1621 KMEIDLKDLEAQIEAANKAR 1640
Score = 34.3 bits (77), Expect = 0.30
Identities = 28/133 (21%), Positives = 64/133 (48%), Gaps = 18/133 (13%)
Query: 60 EQEEMKKQNQQDQHQIQVLEQSILRLEKEIQDLEKAELQISTKEEAILKKLKSIERTTED 119
E EEM++++QQ + +L + + +AE ++ + E + +L + ++ E+
Sbjct: 874 ELEEMERKHQQLLEEKNILAEQL-----------QAETELFAEAEEMRARLAAKKQELEE 922
Query: 120 IIRSVKVEREERAEESIEDIYANIPDLPKSYIPSRLRKEINEEKEDDEQNRKALYAMEIK 179
I+ ++ EE EE I N +++I +++ E+ +++E R+ L ++
Sbjct: 923 ILHDLESRVEE--EEERNQILQNEKKKMQAHI-----QDLEEQLDEEEGARQKLQLEKVT 975
Query: 180 VEKDLKTGESTVL 192
E +K E +L
Sbjct: 976 AEAKIKKMEEEIL 988
Score = 33.9 bits (76), Expect = 0.40
Identities = 44/199 (22%), Positives = 89/199 (44%), Gaps = 21/199 (10%)
Query: 5 ELVKGRLQAITDKRKIQEEISQKRLKIEEDKLKHQHLKKKALREKWLLDGISSGKEQEEM 64
EL K + + + +Q++I++ + +I+E LK Q KK+ + L G +
Sbjct: 1052 ELEKAKRKLDGETTDLQDQIAELQAQIDE--LKLQLAKKEEELQGALARGDDETLHKNNA 1109
Query: 65 KKQNQQDQHQIQVLEQSILRLEKEIQDLEKAELQISTKEEAILKKLKSIERTT--EDIIR 122
K ++ Q QI L++ + EK + +S + EA+ +L+ TT + +R
Sbjct: 1110 LKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELR 1169
Query: 123 SVK----VEREERAEESIEDIYANIPDLPKSYIPS------------RLRKEINEEKEDD 166
+ + E ++ EE ++ A I D+ + + + R + + + K+
Sbjct: 1170 TKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGL 1229
Query: 167 EQNRKALYAMEIKVEKDLK 185
E + K L A E+KV + +K
Sbjct: 1230 ETDNKEL-ACEVKVLQQVK 1247
Score = 32.3 bits (72), Expect = 1.2
Identities = 33/175 (18%), Positives = 78/175 (44%), Gaps = 14/175 (8%)
Query: 20 IQEEISQK--------RLKIEEDKLKHQHLKKKALREKWLLDGISSGKEQEEMKKQNQQD 71
+QEE QK +L+ E++ L+ Q +++ R+ ++ + + KK+ D
Sbjct: 1324 LQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDD 1383
Query: 72 QHQIQVLEQSILRLEKEIQDLEKAELQISTKEEAILKKLKSIERTTEDIIRSVKVERE-- 129
I+ LE++ +L K+ + L + + + + + K +++ +D+ + +R+
Sbjct: 1384 LGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVA 1443
Query: 130 ---ERAEESIEDIYANIPDLPKSYIPSRLRKEINEEKEDDEQNRKALYAMEIKVE 181
E+ ++ + + A + Y R R E E +E + + A+E +E
Sbjct: 1444 SNLEKKQKKFDQLLAEEKSISARYAEERDRAEA-EAREKETKALSLARALEEALE 1497
>gi|146133848 golgi autoantigen, golgin subfamily a, 6 [Homo
sapiens]
Length = 693
Score = 48.5 bits (114), Expect = 2e-05
Identities = 45/203 (22%), Positives = 106/203 (52%), Gaps = 15/203 (7%)
Query: 2 EEAELVKGRLQAITDKRKIQEEISQK---RLKIEEDKLKHQHLKKKALREKWLLDGISSG 58
+E E ++G+LQ+ + + +S++ RL+ +E+ L+ Q ++ +E+
Sbjct: 309 QEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLR 368
Query: 59 KEQEEMKKQNQQDQHQIQVLEQSILRLEKEIQDLEKAELQISTKEEAILKKLKSIERTTE 118
++Q+ +++Q ++ + Q Q L + RL KE + L+K E ++ +EE + KK + +++ E
Sbjct: 369 EQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEE 428
Query: 119 DIIRSVKVEREERAEESIEDIYANIPDLPKSYIPSRLRKEINEEKED-DEQNRKALYAME 177
+ S + +++ E + + ++ + KS + +L +++ E +E DE++ +A
Sbjct: 429 RLALSQNHKLDKQLAEP-QCSFEDLNNEKKSAL--QLEQQVKELQEKLDEEHLEAASHQN 485
Query: 178 IKVEKDLKTGESTVLSSIPLPSD 200
++E T LS + LP +
Sbjct: 486 QQLE--------TQLSLVALPGE 500
>gi|19924131 RAD50 homolog isoform 2 [Homo sapiens]
Length = 1173
Score = 48.1 bits (113), Expect = 2e-05
Identities = 36/131 (27%), Positives = 68/131 (51%), Gaps = 8/131 (6%)
Query: 12 QAITDKRKIQEEISQ---KRLKIEED-KLKHQHLKKKALREKWLLDGISSGKEQEEMKK- 66
Q T+ K+ ++S+ + KI ED +L Q + + ++E+WL D ++ K EE+K+
Sbjct: 836 QKETELNKVIAQLSECEKHKEKINEDMRLMRQDIDTQKIQERWLQDNLTLRKRNEELKEV 895
Query: 67 QNQQDQHQIQVLEQSILRLEKEIQDLEKAELQISTKEEAILKKLKSIERTTEDIIRSVKV 126
+ ++ QH ++ + +L+++ E Q LE+ I L + K E E+II K
Sbjct: 896 EEERKQHLKEMGQMQVLQMKSEHQKLEENIDNIKRNHNLALGRQKGYE---EEIIHFKKE 952
Query: 127 EREERAEESIE 137
RE + ++ E
Sbjct: 953 LREPQFRDAEE 963
Score = 38.5 bits (88), Expect = 0.016
Identities = 38/180 (21%), Positives = 73/180 (40%), Gaps = 34/180 (18%)
Query: 1 MEEAELVKGRLQAITDKRKIQEEISQKRLKIEEDKLKHQHLKKKALREKWLLDGISSGKE 60
M E E K L +T + Q E+ KI + K L GI +
Sbjct: 640 MPEEESAKVCLTDVTIMERFQMELKDVERKIAQQAAK--------------LQGIDLDRT 685
Query: 61 QEEMKKQNQQDQHQIQVLEQSILRLEKEIQDLEKAELQISTKEEAILKKLKSI--ERTTE 118
+++ ++ Q+ QH++ + I K IQD ++ ++ LKS E +E
Sbjct: 686 VQQVNQEKQEKQHKLDTVSSKIELNRKLIQD-----------QQEQIQHLKSTTNELKSE 734
Query: 119 DIIRSVKVEREERAEE-------SIEDIYANIPDLPKSYIPSRLRKEINEEKEDDEQNRK 171
+ S ++R ++ EE ++ +Y I D + P E ++++++ N+K
Sbjct: 735 KLQISTNLQRRQQLEEQTVELSTEVQSLYREIKDAKEQVSPLETTLEKFQQEKEELINKK 794
Score = 31.2 bits (69), Expect = 2.6
Identities = 40/167 (23%), Positives = 81/167 (48%), Gaps = 26/167 (15%)
Query: 18 RKIQEEISQKRLKIEEDKLKHQHLKKKALRE----KWLLDGISSGKEQEEMKKQNQQD-- 71
R+ QE ++ ++ D + + LK+K + E K L I K + KKQN+
Sbjct: 262 RERQEGEAKTANQLMNDFAEKETLKQKQIDEIRDKKTGLGRIIELKSEILSKKQNELKNV 321
Query: 72 QHQIQVLEQSILRLEKEIQDLEKAELQISTKE-----EAILKKLKSIERTTEDIIRSVKV 126
++++Q LE S R+ + Q+L KAE ++S E E + ++ S++ D+ R+++
Sbjct: 322 KYELQQLEGSSDRILELDQELIKAERELSKAEKNSNVETLKMEVISLQNEKADLDRTLR- 380
Query: 127 EREERAEESIEDIYANIPDLPKSYIPSRLRKEI--NEEKEDDEQNRK 171
+ ++ +E + + +R + E+ ++ + DEQ RK
Sbjct: 381 ----KLDQEMEQL--------NHHTTTRTQMEMLTKDKADKDEQIRK 415
>gi|19924129 RAD50 homolog isoform 1 [Homo sapiens]
Length = 1312
Score = 48.1 bits (113), Expect = 2e-05
Identities = 36/131 (27%), Positives = 68/131 (51%), Gaps = 8/131 (6%)
Query: 12 QAITDKRKIQEEISQ---KRLKIEED-KLKHQHLKKKALREKWLLDGISSGKEQEEMKK- 66
Q T+ K+ ++S+ + KI ED +L Q + + ++E+WL D ++ K EE+K+
Sbjct: 975 QKETELNKVIAQLSECEKHKEKINEDMRLMRQDIDTQKIQERWLQDNLTLRKRNEELKEV 1034
Query: 67 QNQQDQHQIQVLEQSILRLEKEIQDLEKAELQISTKEEAILKKLKSIERTTEDIIRSVKV 126
+ ++ QH ++ + +L+++ E Q LE+ I L + K E E+II K
Sbjct: 1035 EEERKQHLKEMGQMQVLQMKSEHQKLEENIDNIKRNHNLALGRQKGYE---EEIIHFKKE 1091
Query: 127 EREERAEESIE 137
RE + ++ E
Sbjct: 1092 LREPQFRDAEE 1102
Score = 38.5 bits (88), Expect = 0.016
Identities = 38/180 (21%), Positives = 73/180 (40%), Gaps = 34/180 (18%)
Query: 1 MEEAELVKGRLQAITDKRKIQEEISQKRLKIEEDKLKHQHLKKKALREKWLLDGISSGKE 60
M E E K L +T + Q E+ KI + K L GI +
Sbjct: 779 MPEEESAKVCLTDVTIMERFQMELKDVERKIAQQAAK--------------LQGIDLDRT 824
Query: 61 QEEMKKQNQQDQHQIQVLEQSILRLEKEIQDLEKAELQISTKEEAILKKLKSI--ERTTE 118
+++ ++ Q+ QH++ + I K IQD ++ ++ LKS E +E
Sbjct: 825 VQQVNQEKQEKQHKLDTVSSKIELNRKLIQD-----------QQEQIQHLKSTTNELKSE 873
Query: 119 DIIRSVKVEREERAEE-------SIEDIYANIPDLPKSYIPSRLRKEINEEKEDDEQNRK 171
+ S ++R ++ EE ++ +Y I D + P E ++++++ N+K
Sbjct: 874 KLQISTNLQRRQQLEEQTVELSTEVQSLYREIKDAKEQVSPLETTLEKFQQEKEELINKK 933
Score = 31.2 bits (69), Expect = 2.6
Identities = 40/167 (23%), Positives = 81/167 (48%), Gaps = 26/167 (15%)
Query: 18 RKIQEEISQKRLKIEEDKLKHQHLKKKALRE----KWLLDGISSGKEQEEMKKQNQQD-- 71
R+ QE ++ ++ D + + LK+K + E K L I K + KKQN+
Sbjct: 401 RERQEGEAKTANQLMNDFAEKETLKQKQIDEIRDKKTGLGRIIELKSEILSKKQNELKNV 460
Query: 72 QHQIQVLEQSILRLEKEIQDLEKAELQISTKE-----EAILKKLKSIERTTEDIIRSVKV 126
++++Q LE S R+ + Q+L KAE ++S E E + ++ S++ D+ R+++
Sbjct: 461 KYELQQLEGSSDRILELDQELIKAERELSKAEKNSNVETLKMEVISLQNEKADLDRTLR- 519
Query: 127 EREERAEESIEDIYANIPDLPKSYIPSRLRKEI--NEEKEDDEQNRK 171
+ ++ +E + + +R + E+ ++ + DEQ RK
Sbjct: 520 ----KLDQEMEQL--------NHHTTTRTQMEMLTKDKADKDEQIRK 554
>gi|22758136 MAP7 domain containing 2 [Homo sapiens]
Length = 732
Score = 48.1 bits (113), Expect = 2e-05
Identities = 39/157 (24%), Positives = 86/157 (54%), Gaps = 11/157 (7%)
Query: 2 EEAELVKGRLQAITDKRKIQEEISQKRLKIEEDKLKHQHLKKKALREKWLLDGISSGKEQ 61
EE E V+ Q ++ +++ + ++RL++EE+ K + +K+ EK +G K
Sbjct: 418 EEQERVEKEEQDRLEREELKRKAEEERLRLEEEARKQEEERKRQEEEKKKQEGEEKRKAG 477
Query: 62 EEMKKQNQQDQHQIQVLEQSILRLEKEIQDLEKAELQISTKEEAILKKLKSIERTTEDII 121
EE K++ +++ +L++ + ++E +EK + TK + ++++ +ER E I+
Sbjct: 478 EEAKRKAEEE----LLLKEKQEQEKQEKAMIEKQKEAAETKAREVAEQMR-LER--EQIM 530
Query: 122 RSVKVEREERAEESIEDIYANIPDLPKSYIPSRLRKE 158
++ ER ER ++ I++I + KS +P +++KE
Sbjct: 531 LQIEQERLER-KKRIDEI---MKRTRKSDVPPQVKKE 563
Score = 30.8 bits (68), Expect = 3.4
Identities = 26/101 (25%), Positives = 48/101 (47%), Gaps = 24/101 (23%)
Query: 84 RLEKEIQDLEKAELQISTKEEAILKKLKSIERTTEDIIRSVKVEREERAEESIEDIYANI 143
RL+KE ++ E+ E KEE + + ++R E+ +++E E R +E
Sbjct: 412 RLQKEQEEQERVE-----KEEQDRLEREELKRKAEE--ERLRLEEEARKQEE-------- 456
Query: 144 PDLPKSYIPSRLRKEINEEKEDDEQNRKALYAMEIKVEKDL 184
R R+E ++K++ E+ RKA + K E++L
Sbjct: 457 ---------ERKRQEEEKKKQEGEEKRKAGEEAKRKAEEEL 488
>gi|239735588 TRAF2 and NCK interacting kinase isoform 6 [Homo
sapiens]
Length = 1297
Score = 47.8 bits (112), Expect = 3e-05
Identities = 30/148 (20%), Positives = 80/148 (54%), Gaps = 13/148 (8%)
Query: 2 EEAELVKGRLQAITDKRKIQEEISQKRLKIEEDKLKHQHLKKKALREKWLL--------- 52
++ E + + Q + +++K EE ++R ++EE + + + L+K+ RE+
Sbjct: 376 QQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREE 435
Query: 53 DGISSGKEQEEMKKQNQQDQHQIQVLEQSILRLEKEIQDLEKAELQISTKEEAILKKLKS 112
+ + EQE +++Q +++Q Q+++L+Q +L + + + ++ +L+ + E + ++LK
Sbjct: 436 ERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQLEEQRQAERLQRQLKQ 495
Query: 113 IERTTEDIIRSVKVEREERAEESIEDIY 140
D + S++ +R+E+ + +Y
Sbjct: 496 ----ERDYLVSLQHQRQEQRPVEKKPLY 519
Score = 35.8 bits (81), Expect = 0.10
Identities = 38/171 (22%), Positives = 84/171 (49%), Gaps = 20/171 (11%)
Query: 20 IQEEISQKRLKIEEDKLK-HQHLKKKALREKWLLDGISSGKEQEEMKKQNQQDQHQIQVL 78
I+++ ++++++I+ LK H KK EK + SG E+EE + + + + +
Sbjct: 289 IRDQPNERQVRIQ---LKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLP 345
Query: 79 EQSILRLEKEIQDLEKAELQISTKEEAILK-KLKSIERTTEDIIRSVKVEREERAEESIE 137
+S LR +D + +L + EA+ + +L+ +R E+ R + ER++R EE E
Sbjct: 346 GESTLR-----RDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKE 400
Query: 138 DIYANIPDLPKSYIPSRLRKEINEEKEDDEQNRKALYAMEIKVEKDLKTGE 188
+ + + R+E E ++ E+ ++ Y +++ E++ + E
Sbjct: 401 Q---------RRRLEEQQRRE-KELRKQQEREQRRHYEEQMRREEERRRAE 441
Score = 29.6 bits (65), Expect = 7.5
Identities = 23/130 (17%), Positives = 60/130 (46%), Gaps = 5/130 (3%)
Query: 59 KEQEEMKKQNQQDQHQIQVLEQSILRLEKEIQDLEKAELQISTKEEAILKKLKSIERTTE 118
+ Q+ ++Q + ++H+ Q+L + R+E++ + + E Q ++E ++ + R E
Sbjct: 369 RRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYE 428
Query: 119 DIIRSVKVER-----EERAEESIEDIYANIPDLPKSYIPSRLRKEINEEKEDDEQNRKAL 173
+ +R + R +E +E+ + L + + + + K+ +EQ +
Sbjct: 429 EQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQLEEQRQAER 488
Query: 174 YAMEIKVEKD 183
++K E+D
Sbjct: 489 LQRQLKQERD 498
>gi|239735586 TRAF2 and NCK interacting kinase isoform 5 [Homo
sapiens]
Length = 1305
Score = 47.8 bits (112), Expect = 3e-05
Identities = 30/148 (20%), Positives = 80/148 (54%), Gaps = 13/148 (8%)
Query: 2 EEAELVKGRLQAITDKRKIQEEISQKRLKIEEDKLKHQHLKKKALREKWLL--------- 52
++ E + + Q + +++K EE ++R ++EE + + + L+K+ RE+
Sbjct: 376 QQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREE 435
Query: 53 DGISSGKEQEEMKKQNQQDQHQIQVLEQSILRLEKEIQDLEKAELQISTKEEAILKKLKS 112
+ + EQE +++Q +++Q Q+++L+Q +L + + + ++ +L+ + E + ++LK
Sbjct: 436 ERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQLEEQRQAERLQRQLKQ 495
Query: 113 IERTTEDIIRSVKVEREERAEESIEDIY 140
D + S++ +R+E+ + +Y
Sbjct: 496 ----ERDYLVSLQHQRQEQRPVEKKPLY 519
Score = 35.8 bits (81), Expect = 0.10
Identities = 38/171 (22%), Positives = 84/171 (49%), Gaps = 20/171 (11%)
Query: 20 IQEEISQKRLKIEEDKLK-HQHLKKKALREKWLLDGISSGKEQEEMKKQNQQDQHQIQVL 78
I+++ ++++++I+ LK H KK EK + SG E+EE + + + + +
Sbjct: 289 IRDQPNERQVRIQ---LKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLP 345
Query: 79 EQSILRLEKEIQDLEKAELQISTKEEAILK-KLKSIERTTEDIIRSVKVEREERAEESIE 137
+S LR +D + +L + EA+ + +L+ +R E+ R + ER++R EE E
Sbjct: 346 GESTLR-----RDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKE 400
Query: 138 DIYANIPDLPKSYIPSRLRKEINEEKEDDEQNRKALYAMEIKVEKDLKTGE 188
+ + + R+E E ++ E+ ++ Y +++ E++ + E
Sbjct: 401 Q---------RRRLEEQQRRE-KELRKQQEREQRRHYEEQMRREEERRRAE 441
Score = 29.6 bits (65), Expect = 7.5
Identities = 23/130 (17%), Positives = 60/130 (46%), Gaps = 5/130 (3%)
Query: 59 KEQEEMKKQNQQDQHQIQVLEQSILRLEKEIQDLEKAELQISTKEEAILKKLKSIERTTE 118
+ Q+ ++Q + ++H+ Q+L + R+E++ + + E Q ++E ++ + R E
Sbjct: 369 RRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYE 428
Query: 119 DIIRSVKVER-----EERAEESIEDIYANIPDLPKSYIPSRLRKEINEEKEDDEQNRKAL 173
+ +R + R +E +E+ + L + + + + K+ +EQ +
Sbjct: 429 EQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQLEEQRQAER 488
Query: 174 YAMEIKVEKD 183
++K E+D
Sbjct: 489 LQRQLKQERD 498
>gi|42794779 myosin 18A isoform b [Homo sapiens]
Length = 2039
Score = 47.4 bits (111), Expect = 3e-05
Identities = 44/173 (25%), Positives = 84/173 (48%), Gaps = 20/173 (11%)
Query: 17 KRKIQEEISQKRLKIEEDKLKHQHLKKKALREKWLLDGISSGKEQEEMKKQNQQDQHQIQ 76
+R+ E+SQ + + +KL+ + L+ REK +L E +K+Q ++ I
Sbjct: 1460 QRRFDSELSQAHEEAQREKLQREKLQ----REKDMLLA-----EAFSLKQQLEEKDMDIA 1510
Query: 77 VLEQSILRLEKEIQDLEKAELQISTKEEAILKKLKSIERTTEDIIRSVKVEREERAE--E 134
Q ++ LE E+QD+ E +K+EA L K+K R E ++ + E +E+A +
Sbjct: 1511 GFTQKVVSLEAELQDISSQE----SKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQ 1566
Query: 135 SIEDIYANIPDLPKSYIPSRLRKEINEEKEDDEQNR----KALYAMEIKVEKD 183
+E + ++ + KE+ E+ E+ R K L ME+++E++
Sbjct: 1567 MLEQAKLRL-EMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEE 1618
Score = 47.4 bits (111), Expect = 3e-05
Identities = 42/186 (22%), Positives = 91/186 (48%), Gaps = 18/186 (9%)
Query: 16 DKRKIQEEISQKRLKIEEDKLKHQHLKKKALREKWLLDGISS-----GKEQEEMKKQNQQ 70
+K +IQ + + + + E KH+ +A R+ ++ + + KE++E++++ Q
Sbjct: 1740 EKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQA 1799
Query: 71 DQHQIQVLEQSIL------RLEKEIQDLEK----AELQISTKEEAILKKLKSIERTTEDI 120
Q Q++ LEQS++ R E +I++LE Q+ E + +++E+ TE+
Sbjct: 1800 LQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEE- 1858
Query: 121 IRSVKVEREERAEESIEDIYANIPDLPKSYIP-SRLRKEINEEKEDDEQNRKALYAMEIK 179
R ++ E R +E + + + D + +R E + +K + E + ++L A
Sbjct: 1859 -RDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQS 1917
Query: 180 VEKDLK 185
++ DLK
Sbjct: 1918 LQADLK 1923
Score = 29.6 bits (65), Expect = 7.5
Identities = 34/158 (21%), Positives = 70/158 (44%), Gaps = 17/158 (10%)
Query: 27 KRLKIEEDKLK--HQHLKKKALREKW----LLDGISSGKEQEEMKKQNQQDQHQIQVLEQ 80
K+ KI++ ++ +++KK + W L + E + ++Q + +IQ L
Sbjct: 1209 KKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDEEIQQLRS 1268
Query: 81 SILRLEKEIQDLEKAELQISTKEEAILKKLKSIERTTEDIIRSVKVEREE--RAEESIED 138
+ + EKE +L ++ ++ + +L T E + + E E RAE+ +++
Sbjct: 1269 KLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERLRAEKEMKE 1328
Query: 139 IYANIPDLPK-------SYIPSRLRK--EINEEKEDDE 167
+ L K + +RL + EIN E +DD+
Sbjct: 1329 LQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDD 1366
>gi|28416946 myosin 18A isoform a [Homo sapiens]
Length = 2054
Score = 47.4 bits (111), Expect = 3e-05
Identities = 44/173 (25%), Positives = 84/173 (48%), Gaps = 20/173 (11%)
Query: 17 KRKIQEEISQKRLKIEEDKLKHQHLKKKALREKWLLDGISSGKEQEEMKKQNQQDQHQIQ 76
+R+ E+SQ + + +KL+ + L+ REK +L E +K+Q ++ I
Sbjct: 1460 QRRFDSELSQAHEEAQREKLQREKLQ----REKDMLLA-----EAFSLKQQLEEKDMDIA 1510
Query: 77 VLEQSILRLEKEIQDLEKAELQISTKEEAILKKLKSIERTTEDIIRSVKVEREERAE--E 134
Q ++ LE E+QD+ E +K+EA L K+K R E ++ + E +E+A +
Sbjct: 1511 GFTQKVVSLEAELQDISSQE----SKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQ 1566
Query: 135 SIEDIYANIPDLPKSYIPSRLRKEINEEKEDDEQNR----KALYAMEIKVEKD 183
+E + ++ + KE+ E+ E+ R K L ME+++E++
Sbjct: 1567 MLEQAKLRL-EMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEE 1618
Score = 47.4 bits (111), Expect = 3e-05
Identities = 42/186 (22%), Positives = 91/186 (48%), Gaps = 18/186 (9%)
Query: 16 DKRKIQEEISQKRLKIEEDKLKHQHLKKKALREKWLLDGISS-----GKEQEEMKKQNQQ 70
+K +IQ + + + + E KH+ +A R+ ++ + + KE++E++++ Q
Sbjct: 1740 EKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQA 1799
Query: 71 DQHQIQVLEQSIL------RLEKEIQDLEK----AELQISTKEEAILKKLKSIERTTEDI 120
Q Q++ LEQS++ R E +I++LE Q+ E + +++E+ TE+
Sbjct: 1800 LQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEE- 1858
Query: 121 IRSVKVEREERAEESIEDIYANIPDLPKSYIP-SRLRKEINEEKEDDEQNRKALYAMEIK 179
R ++ E R +E + + + D + +R E + +K + E + ++L A
Sbjct: 1859 -RDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQS 1917
Query: 180 VEKDLK 185
++ DLK
Sbjct: 1918 LQADLK 1923
Score = 29.6 bits (65), Expect = 7.5
Identities = 34/158 (21%), Positives = 70/158 (44%), Gaps = 17/158 (10%)
Query: 27 KRLKIEEDKLK--HQHLKKKALREKW----LLDGISSGKEQEEMKKQNQQDQHQIQVLEQ 80
K+ KI++ ++ +++KK + W L + E + ++Q + +IQ L
Sbjct: 1209 KKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDEEIQQLRS 1268
Query: 81 SILRLEKEIQDLEKAELQISTKEEAILKKLKSIERTTEDIIRSVKVEREE--RAEESIED 138
+ + EKE +L ++ ++ + +L T E + + E E RAE+ +++
Sbjct: 1269 KLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERLRAEKEMKE 1328
Query: 139 IYANIPDLPK-------SYIPSRLRK--EINEEKEDDE 167
+ L K + +RL + EIN E +DD+
Sbjct: 1329 LQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDD 1366
Score = 29.6 bits (65), Expect = 7.5
Identities = 30/161 (18%), Positives = 72/161 (44%), Gaps = 27/161 (16%)
Query: 22 EEISQKRLKIEEDKLKHQHLKKKALREKWLLDGISSGKEQEEMKKQNQQDQHQIQVLEQS 81
E KRL+ +LK K R++ + + +E+E+ K+ L++
Sbjct: 1834 ERTQVKRLESLASRLKENMEKLTEERDQRI---AAENREKEQNKR-----------LQRQ 1879
Query: 82 ILRLEKEIQDLEKAELQISTKEEAILKKLKSIERTTEDIIRSVK------------VERE 129
+ ++E+ +L + E + S K+ + L+S+E + + +K +E E
Sbjct: 1880 LRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIEDE 1939
Query: 130 ERAEESIEDIYANIPDLPKSYIPSRLRKEINEEKEDDEQNR 170
++E+ ED+ ++ D+ Y + + E + + + + ++R
Sbjct: 1940 MESDEN-EDLINSLQDMVTKYQKRKNKLEGDSDVDSELEDR 1979
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 47.4 bits (111), Expect = 3e-05
Identities = 40/178 (22%), Positives = 87/178 (48%), Gaps = 29/178 (16%)
Query: 10 RLQAITDKRKIQEEISQKR-LKIEEDKLKHQHL-KKKALREKWLLDGISSGKEQEEMKKQ 67
+++ + +RK +EE + R L+ EE++ +HQ L +KK E+ L + K E ++Q
Sbjct: 631 KMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQ 690
Query: 68 NQQDQHQIQVLEQSILRLEKEIQDLEKAELQISTKEEAILKKLKSIERTTEDIIRSVKVE 127
+++Q + EQ E+ Q+ + E Q++ +E ++ ER ++ ++++++
Sbjct: 691 ERREQER---REQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQ 747
Query: 128 REERAEESIEDIYANIPDLPKSYIPSRLRKEINEEKEDDEQNRKALYAMEIKVEKDLK 185
+E+ L++E+ E+K+ +EQ R A ++ + EK K
Sbjct: 748 KEQ------------------------LQRELEEKKKKEEQQRLAERQLQEEQEKKAK 781
Score = 43.5 bits (101), Expect = 5e-04
Identities = 36/177 (20%), Positives = 87/177 (49%), Gaps = 15/177 (8%)
Query: 3 EAELVKGRLQAITDKRKIQEEISQKRLKIEEDKLKHQHLKKKALREKWLLDGISSGKEQE 62
+ V+ Q + + R+ +E +R K+EED K + L++ L+ + L + +E+
Sbjct: 531 KCSFVEKERQRLENLRRKEEAEQLRRQKVEED--KRRRLEEVKLKREERLRKVLQARERV 588
Query: 63 EMKKQNQQDQHQIQVLEQSILRLEKEIQDLEKAEL-QISTKEEAILKKLKSIE--RTTED 119
E K+ ++ Q +EQ +++++ + ++ L + K++A KK++ +E R E+
Sbjct: 589 EQMKEEKKKQ-----IEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEE 643
Query: 120 IIRSVKVEREERAEESIEDIYANIPD-----LPKSYIPSRLRKEINEEKEDDEQNRK 171
R ++ ++E E +++ + L K+ RL ++ +E+ + E+ +
Sbjct: 644 EARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQ 700
Score = 42.4 bits (98), Expect = 0.001
Identities = 32/126 (25%), Positives = 65/126 (51%), Gaps = 1/126 (0%)
Query: 10 RLQAITDKRKIQEEISQKRLKIEEDKLKHQHLKKKALREKWLLDGISSGKEQEEMKKQNQ 69
R Q + K+K +EE + R E +L Q +++ +E+ + + ++E ++Q +
Sbjct: 659 RHQELLQKKK-EEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQER 717
Query: 70 QDQHQIQVLEQSILRLEKEIQDLEKAELQISTKEEAILKKLKSIERTTEDIIRSVKVERE 129
Q Q + EQ L+ E+E+Q+ EKA + + L++ K E R ++ E+E
Sbjct: 718 QLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQE 777
Query: 130 ERAEES 135
++A+E+
Sbjct: 778 KKAKEA 783
Score = 41.6 bits (96), Expect = 0.002
Identities = 37/177 (20%), Positives = 88/177 (49%), Gaps = 23/177 (12%)
Query: 2 EEAELVKGRLQAITDKRKIQEEISQKRLKIEEDKLKHQHLKKKALREKWLLDGISSGKEQ 61
EEAE ++ ++K++E+ KR ++EE KLK + +K L+ + ++ + K++
Sbjct: 549 EEAEQLR--------RQKVEED---KRRRLEEVKLKREERLRKVLQARERVEQMKEEKKK 597
Query: 62 EEMKKQNQQDQHQIQVLEQSIL--RLEKEIQDLEKAELQISTKEEAILKKLKSI-----E 114
+ +K Q D+ + E+ + + +K+ + E++ K+E ++L+ + E
Sbjct: 598 QIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEE 657
Query: 115 RTTEDIIRSVKVEREERAEESIEDIYANIPDLPKSYIPSRLRKEINEEKEDDEQNRK 171
R +++++ K E +ER ++ A L + R +E E++ +++ R+
Sbjct: 658 RRHQELLQKKKEEEQERLRKA-----AEAKRLAEQREQERREQERREQERREQERRE 709
Score = 31.6 bits (70), Expect = 2.0
Identities = 28/128 (21%), Positives = 57/128 (44%), Gaps = 21/128 (16%)
Query: 59 KEQEEMKKQNQQDQHQIQVLEQSIL----RLEKEIQDLEKAELQISTKEEAILKKLKSIE 114
KE+ E ++ + ++ + + LE+ L RL K +Q E+ E K++ I +K I+
Sbjct: 548 KEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQID 607
Query: 115 RTTEDIIRSVKVEREERAEESIEDIYANIPDLPKSYIPSRLRKEINEEKEDDEQNRKALY 174
TE K + E AEE K ++ +E+ ++ +E+ R+ +
Sbjct: 608 EKTE------KAKEERLAEEK-----------AKKKAAAKKMEEVEARRKQEEEARRLRW 650
Query: 175 AMEIKVEK 182
+ + E+
Sbjct: 651 LQQEEEER 658
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 47.4 bits (111), Expect = 3e-05
Identities = 40/178 (22%), Positives = 87/178 (48%), Gaps = 29/178 (16%)
Query: 10 RLQAITDKRKIQEEISQKR-LKIEEDKLKHQHL-KKKALREKWLLDGISSGKEQEEMKKQ 67
+++ + +RK +EE + R L+ EE++ +HQ L +KK E+ L + K E ++Q
Sbjct: 627 KMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQ 686
Query: 68 NQQDQHQIQVLEQSILRLEKEIQDLEKAELQISTKEEAILKKLKSIERTTEDIIRSVKVE 127
+++Q + EQ E+ Q+ + E Q++ +E ++ ER ++ ++++++
Sbjct: 687 ERREQER---REQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQ 743
Query: 128 REERAEESIEDIYANIPDLPKSYIPSRLRKEINEEKEDDEQNRKALYAMEIKVEKDLK 185
+E+ L++E+ E+K+ +EQ R A ++ + EK K
Sbjct: 744 KEQ------------------------LQRELEEKKKKEEQQRLAERQLQEEQEKKAK 777
Score = 42.4 bits (98), Expect = 0.001
Identities = 32/126 (25%), Positives = 65/126 (51%), Gaps = 1/126 (0%)
Query: 10 RLQAITDKRKIQEEISQKRLKIEEDKLKHQHLKKKALREKWLLDGISSGKEQEEMKKQNQ 69
R Q + K+K +EE + R E +L Q +++ +E+ + + ++E ++Q +
Sbjct: 655 RHQELLQKKK-EEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQER 713
Query: 70 QDQHQIQVLEQSILRLEKEIQDLEKAELQISTKEEAILKKLKSIERTTEDIIRSVKVERE 129
Q Q + EQ L+ E+E+Q+ EKA + + L++ K E R ++ E+E
Sbjct: 714 QLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQE 773
Query: 130 ERAEES 135
++A+E+
Sbjct: 774 KKAKEA 779
Score = 41.6 bits (96), Expect = 0.002
Identities = 35/168 (20%), Positives = 84/168 (50%), Gaps = 15/168 (8%)
Query: 12 QAITDKRKIQEEISQKRLKIEEDKLKHQHLKKKALREKWLLDGISSGKEQEEMKKQNQQD 71
Q + + R+ +E +R K+EEDK + + K RE+ L + + + E+MK++ ++
Sbjct: 536 QRLENLRRKEEAEQLRRQKVEEDKRRRLE-EVKLKREERLRKVLQARERVEQMKEEKKKQ 594
Query: 72 QHQIQVLEQSILRLEKEIQDLEKAEL-QISTKEEAILKKLKSIE--RTTEDIIRSVKVER 128
+EQ +++++ + ++ L + K++A KK++ +E R E+ R ++ +
Sbjct: 595 ------IEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQ 648
Query: 129 EERAEESIEDIYANIPD-----LPKSYIPSRLRKEINEEKEDDEQNRK 171
+E E +++ + L K+ RL ++ +E+ + E+ +
Sbjct: 649 QEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQ 696
Score = 41.6 bits (96), Expect = 0.002
Identities = 37/177 (20%), Positives = 88/177 (49%), Gaps = 23/177 (12%)
Query: 2 EEAELVKGRLQAITDKRKIQEEISQKRLKIEEDKLKHQHLKKKALREKWLLDGISSGKEQ 61
EEAE ++ ++K++E+ KR ++EE KLK + +K L+ + ++ + K++
Sbjct: 545 EEAEQLR--------RQKVEED---KRRRLEEVKLKREERLRKVLQARERVEQMKEEKKK 593
Query: 62 EEMKKQNQQDQHQIQVLEQSIL--RLEKEIQDLEKAELQISTKEEAILKKLKSI-----E 114
+ +K Q D+ + E+ + + +K+ + E++ K+E ++L+ + E
Sbjct: 594 QIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEE 653
Query: 115 RTTEDIIRSVKVEREERAEESIEDIYANIPDLPKSYIPSRLRKEINEEKEDDEQNRK 171
R +++++ K E +ER ++ A L + R +E E++ +++ R+
Sbjct: 654 RRHQELLQKKKEEEQERLRKA-----AEAKRLAEQREQERREQERREQERREQERRE 705
Score = 31.6 bits (70), Expect = 2.0
Identities = 28/128 (21%), Positives = 57/128 (44%), Gaps = 21/128 (16%)
Query: 59 KEQEEMKKQNQQDQHQIQVLEQSIL----RLEKEIQDLEKAELQISTKEEAILKKLKSIE 114
KE+ E ++ + ++ + + LE+ L RL K +Q E+ E K++ I +K I+
Sbjct: 544 KEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQID 603
Query: 115 RTTEDIIRSVKVEREERAEESIEDIYANIPDLPKSYIPSRLRKEINEEKEDDEQNRKALY 174
TE K + E AEE K ++ +E+ ++ +E+ R+ +
Sbjct: 604 EKTE------KAKEERLAEEK-----------AKKKAAAKKMEEVEARRKQEEEARRLRW 646
Query: 175 AMEIKVEK 182
+ + E+
Sbjct: 647 LQQEEEER 654
>gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo
sapiens]
Length = 1116
Score = 47.0 bits (110), Expect = 5e-05
Identities = 52/209 (24%), Positives = 103/209 (49%), Gaps = 31/209 (14%)
Query: 2 EEAELVKGRLQAITDKRKI-QEEISQKRLKIEEDKLKHQHLKKKALREKWLLDGISSGKE 60
+ E++K L A + I Q E+ RL++EE K + K K +++ G +G E
Sbjct: 501 QHIEVLKESLTAKEQRAAILQTEVDALRLRLEE-KETMLNKKTKQIQDMAEEKGTQAG-E 558
Query: 61 QEEMKKQNQQDQHQIQVLEQSILRLEKEIQDLEK------------------AELQISTK 102
++K + ++ VL++ I L+++++D EK + ++T
Sbjct: 559 IHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTL 618
Query: 103 EEAILKKLKSIERTTEDIIRSVKVEREERAEESIEDIYANIPDLPKSYIPSRLRKEINEE 162
EEA+ +K ++IER E R ERE+ +E I++ ++ DL + S L+ +++E+
Sbjct: 619 EEALAEKERTIERLKEQRDRD---EREK--QEEIDNYKKDLKDLKEKV--SLLQGDLSEK 671
Query: 163 KE---DDEQNRKALYAMEIKVEKDLKTGE 188
+ D +++ +L + +K + LKT E
Sbjct: 672 EASLLDLKEHASSLASSGLKKDSRLKTLE 700
Score = 35.4 bits (80), Expect = 0.14
Identities = 46/225 (20%), Positives = 103/225 (45%), Gaps = 34/225 (15%)
Query: 1 MEEAELVKGRLQAITDKRKIQEEISQKRLKIEE-DKLKHQHLKKKALREKWLLDGISSGK 59
+EEA + L +++Q+ + +K +IEE ++ + ++ A RE L
Sbjct: 811 LEEARRREDNLN--DSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLA------- 861
Query: 60 EQEEMKKQNQQDQHQIQVLEQSILRLEKEIQDLEKAELQISTKEEAILKKLKSIERTTED 119
QEE + N + Q +E+ ++ +EK Q+LE + ++S+ ++++ +K E
Sbjct: 862 -QEESARTNAEKQ-----VEELLMAMEKVKQELESMKAKLSSTQQSLAEK--------ET 907
Query: 120 IIRSVKVEREERAEESIEDIYANIPDLPKSYIPSRLRKEINEEKEDDEQNRKALYAMEIK 179
+ +++ ER + EE +E + + E++ K+ ++ AL + +
Sbjct: 908 HLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLELSSSKKKTQEEVAALKREKDR 967
Query: 180 VEKDLKTGESTVLSSIPLPSDDFKGTGIKVYDDGQKSVYAVSSNH 224
+ + LK + + L +D+++ DD KS ++ +NH
Sbjct: 968 LVQQLK---QQTQNRMKLMADNYE-------DDHFKSSHSNQTNH 1002
Score = 33.9 bits (76), Expect = 0.40
Identities = 41/185 (22%), Positives = 80/185 (43%), Gaps = 36/185 (19%)
Query: 21 QEEISQKRLKIEEDKLKHQ----------HLKKKALREKWLLDGISSGKEQEEM-KKQNQ 69
+ ++ +K ++++E KL LKK+ K I+ KEQ + +++NQ
Sbjct: 164 ENDLLRKDVEVKESKLSSSMNSIKTFWSPELKKERALRKDEASKITIWKEQYRVVQEENQ 223
Query: 70 QDQHQIQVLEQSILRLEKEIQDLEKAELQISTKEEAILKKLKSIERTTEDIIRSVKVERE 129
Q IQ L+ LR+++++ L + + T E + + TE+ + + E E
Sbjct: 224 HMQMTIQALQDE-LRIQRDLNQLFQQDSSSRTGEPCVAE-------LTEENFQRLHAEHE 275
Query: 130 ERAEESIEDIYANIPDLPKSYIPSRLRKEINEEKEDDEQNRKALYAMEIKVEKDLKTGES 189
+A+E LRK + E + E ++ L A + ++K L+ +S
Sbjct: 276 RQAKELF-----------------LLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQS 318
Query: 190 TVLSS 194
LS+
Sbjct: 319 KGLSA 323
Score = 29.6 bits (65), Expect = 7.5
Identities = 42/180 (23%), Positives = 71/180 (39%), Gaps = 17/180 (9%)
Query: 18 RKIQEEISQKRLKIE--EDKLKHQH-LKKKALREKWLLDGISSGKEQEEMKKQNQQDQHQ 74
R +QEE ++ I+ +D+L+ Q L + ++ G E E Q +H+
Sbjct: 216 RVVQEENQHMQMTIQALQDELRIQRDLNQLFQQDSSSRTGEPCVAELTEENFQRLHAEHE 275
Query: 75 IQV---------LEQSILRLEKEIQDLEKAELQISTKEEAILKKLKSIERTTEDIIRSVK 125
Q LE+ LR+E + Q L + I E + K S + T ED R+ +
Sbjct: 276 RQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRR 335
Query: 126 VEREERAEESIEDIYANIPDLPKSYIPSRLRKEINEEKEDDEQNRKALYAMEIKVEKDLK 185
+ E +E + K S LR+E++ E+ + K + KD K
Sbjct: 336 LAEAEMHVHHLESLLEQ-----KEKENSMLREEMHRRFENAPDSAKTKALQTVIEMKDSK 390
>gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]
Length = 1088
Score = 47.0 bits (110), Expect = 5e-05
Identities = 52/209 (24%), Positives = 103/209 (49%), Gaps = 31/209 (14%)
Query: 2 EEAELVKGRLQAITDKRKI-QEEISQKRLKIEEDKLKHQHLKKKALREKWLLDGISSGKE 60
+ E++K L A + I Q E+ RL++EE K + K K +++ G +G E
Sbjct: 473 QHIEVLKESLTAKEQRAAILQTEVDALRLRLEE-KETMLNKKTKQIQDMAEEKGTQAG-E 530
Query: 61 QEEMKKQNQQDQHQIQVLEQSILRLEKEIQDLEK------------------AELQISTK 102
++K + ++ VL++ I L+++++D EK + ++T
Sbjct: 531 IHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTL 590
Query: 103 EEAILKKLKSIERTTEDIIRSVKVEREERAEESIEDIYANIPDLPKSYIPSRLRKEINEE 162
EEA+ +K ++IER E R ERE+ +E I++ ++ DL + S L+ +++E+
Sbjct: 591 EEALAEKERTIERLKEQRDRD---EREK--QEEIDNYKKDLKDLKEKV--SLLQGDLSEK 643
Query: 163 KE---DDEQNRKALYAMEIKVEKDLKTGE 188
+ D +++ +L + +K + LKT E
Sbjct: 644 EASLLDLKEHASSLASSGLKKDSRLKTLE 672
Score = 35.4 bits (80), Expect = 0.14
Identities = 46/225 (20%), Positives = 103/225 (45%), Gaps = 34/225 (15%)
Query: 1 MEEAELVKGRLQAITDKRKIQEEISQKRLKIEE-DKLKHQHLKKKALREKWLLDGISSGK 59
+EEA + L +++Q+ + +K +IEE ++ + ++ A RE L
Sbjct: 783 LEEARRREDNLN--DSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLA------- 833
Query: 60 EQEEMKKQNQQDQHQIQVLEQSILRLEKEIQDLEKAELQISTKEEAILKKLKSIERTTED 119
QEE + N + Q +E+ ++ +EK Q+LE + ++S+ ++++ +K E
Sbjct: 834 -QEESARTNAEKQ-----VEELLMAMEKVKQELESMKAKLSSTQQSLAEK--------ET 879
Query: 120 IIRSVKVEREERAEESIEDIYANIPDLPKSYIPSRLRKEINEEKEDDEQNRKALYAMEIK 179
+ +++ ER + EE +E + + E++ K+ ++ AL + +
Sbjct: 880 HLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLELSSSKKKTQEEVAALKREKDR 939
Query: 180 VEKDLKTGESTVLSSIPLPSDDFKGTGIKVYDDGQKSVYAVSSNH 224
+ + LK + + L +D+++ DD KS ++ +NH
Sbjct: 940 LVQQLK---QQTQNRMKLMADNYE-------DDHFKSSHSNQTNH 974
Score = 33.9 bits (76), Expect = 0.40
Identities = 41/185 (22%), Positives = 80/185 (43%), Gaps = 36/185 (19%)
Query: 21 QEEISQKRLKIEEDKLKHQ----------HLKKKALREKWLLDGISSGKEQEEM-KKQNQ 69
+ ++ +K ++++E KL LKK+ K I+ KEQ + +++NQ
Sbjct: 164 ENDLLRKDVEVKESKLSSSMNSIKTFWSPELKKERALRKDEASKITIWKEQYRVVQEENQ 223
Query: 70 QDQHQIQVLEQSILRLEKEIQDLEKAELQISTKEEAILKKLKSIERTTEDIIRSVKVERE 129
Q IQ L+ LR+++++ L + + T E + + TE+ + + E E
Sbjct: 224 HMQMTIQALQDE-LRIQRDLNQLFQQDSSSRTGEPCVAE-------LTEENFQRLHAEHE 275
Query: 130 ERAEESIEDIYANIPDLPKSYIPSRLRKEINEEKEDDEQNRKALYAMEIKVEKDLKTGES 189
+A+E LRK + E + E ++ L A + ++K L+ +S
Sbjct: 276 RQAKELF-----------------LLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQS 318
Query: 190 TVLSS 194
LS+
Sbjct: 319 KGLSA 323
Score = 29.6 bits (65), Expect = 7.5
Identities = 42/180 (23%), Positives = 71/180 (39%), Gaps = 17/180 (9%)
Query: 18 RKIQEEISQKRLKIE--EDKLKHQH-LKKKALREKWLLDGISSGKEQEEMKKQNQQDQHQ 74
R +QEE ++ I+ +D+L+ Q L + ++ G E E Q +H+
Sbjct: 216 RVVQEENQHMQMTIQALQDELRIQRDLNQLFQQDSSSRTGEPCVAELTEENFQRLHAEHE 275
Query: 75 IQV---------LEQSILRLEKEIQDLEKAELQISTKEEAILKKLKSIERTTEDIIRSVK 125
Q LE+ LR+E + Q L + I E + K S + T ED R+ +
Sbjct: 276 RQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRR 335
Query: 126 VEREERAEESIEDIYANIPDLPKSYIPSRLRKEINEEKEDDEQNRKALYAMEIKVEKDLK 185
+ E +E + K S LR+E++ E+ + K + KD K
Sbjct: 336 LAEAEMHVHHLESLLEQ-----KEKENSMLREEMHRRFENAPDSAKTKALQTVIEMKDSK 390
>gi|156104874 envoplakin [Homo sapiens]
Length = 2033
Score = 47.0 bits (110), Expect = 5e-05
Identities = 47/194 (24%), Positives = 94/194 (48%), Gaps = 31/194 (15%)
Query: 1 MEEAELVK----GRLQAITDKRKIQEEISQKR-------LKIEEDKLKHQHLKKKALREK 49
+EE E+V+ +L+ + K Q E KR L++ K+ K+K ++
Sbjct: 954 LEEKEVVEFYRDPQLEGSLSRVKAQVEEEGKRRAGLQADLEVAAQKVVQLESKRKTMQPH 1013
Query: 50 WLLDGISSGKEQEEMKKQNQQDQHQIQ-------VLEQSILRLEKEIQDLEKAELQISTK 102
L ++ + + Q Q + QIQ V+ + L+KE+ LEK E+ + K
Sbjct: 1014 LLTKEVTQVERDPGLDSQAAQLRIQIQQLRGEDAVISARLEGLKKELLALEKREVDV--K 1071
Query: 103 EEAILKKLKSIERTTEDI--IRSVKVEREE------RAEESIEDIYANIPDLPK---SYI 151
E+ ++K++ +E+ E + ++++++ EE +AEE++ + A I DL + S
Sbjct: 1072 EKVVVKEVVKVEKNLEMVKAAQALRLQMEEDAARRKQAEEAVAKLQARIEDLERAISSVE 1131
Query: 152 PSRLRKEINEEKED 165
P + KE+ + ++D
Sbjct: 1132 PKVIVKEVKKVEQD 1145
Score = 37.4 bits (85), Expect = 0.036
Identities = 25/132 (18%), Positives = 69/132 (52%), Gaps = 10/132 (7%)
Query: 59 KEQEEMKKQNQQDQHQIQVLEQSILRLEKEIQDLEKAELQISTKEEAILKKLKSIER--- 115
K + ++ Q ++D + + E+++ +L+ I+DLE+A + K I+K++K +E+
Sbjct: 1090 KAAQALRLQMEEDAARRKQAEEAVAKLQARIEDLERAISSVEPK--VIVKEVKKVEQDPG 1147
Query: 116 TTEDIIRSVKVEREERAEES-----IEDIYANIPDLPKSYIPSRLRKEINEEKEDDEQNR 170
++ R + EER + + + D+++ + K +L++ ++E + D +
Sbjct: 1148 LLQESSRLRSLLEEERTKNATLARELSDLHSKYSVVEKQRPKVQLQERVHEIFQVDPETE 1207
Query: 171 KALYAMEIKVEK 182
+ + ++ K+++
Sbjct: 1208 QEITRLKAKLQE 1219
Score = 37.0 bits (84), Expect = 0.047
Identities = 40/190 (21%), Positives = 98/190 (51%), Gaps = 24/190 (12%)
Query: 5 ELVKGRLQAITDKRKIQEEISQKRLKI--EEDKLKHQH------LKKKALREKWL---LD 53
EL RL + ++RK +E++ + + + ++ KL+ +H L ++ R + L +
Sbjct: 1353 ELQSKRL--LLERRKPEEKVVVQEVVVTQKDPKLREEHSRLSGSLDEEVGRRRQLELEVQ 1410
Query: 54 GISSGKEQEEMKKQNQQDQHQIQVLEQSILRLEKEIQDLEKAELQISTKEEAILKKLKSI 113
+ +G E++E Q+D+ + +E+ + +L IQ+LEK + +E+ I++++ +
Sbjct: 1411 QLRAGVEEQEGLLSFQEDRSKKLAVERELRQLTLRIQELEKRPPTV--QEKIIMEEVVKL 1468
Query: 114 ERTTEDIIRSVKVEREERAEESIEDIYANIPDLPKSYIPSRLRKEINEEKEDDEQNRKAL 173
E+ D+ +S + R + +E + + +L + +++ ++ ++ + E K +
Sbjct: 1469 EK-DPDLEKSTEALRWDLDQEKTQ-----VTELNRECKNLQVQIDVLQKAKSQE---KTI 1519
Query: 174 YAMEIKVEKD 183
Y I+V+KD
Sbjct: 1520 YKEVIRVQKD 1529
Score = 32.7 bits (73), Expect = 0.89
Identities = 35/183 (19%), Positives = 87/183 (47%), Gaps = 24/183 (13%)
Query: 16 DKRKIQEEISQKRLKIEEDKLKHQHLKKKALREKWLLDGISSGKEQEEMKKQNQQDQHQI 75
++ ++ E ++++R + + + + L+++ R + L G + +E+ E+++ Q +
Sbjct: 1535 ERARVWEMLNRERTARQAREEEARRLRERIDRAETL--GRTWSREESELQRARDQADQEC 1592
Query: 76 QVLEQSILRLEKEIQ----DLEKAELQISTKEEAILKKLKSIERTTEDIIRSVKVEREE- 130
L+Q + LE++ Q L++ +S K E+ ++ K+ +R E + RE+
Sbjct: 1593 GRLQQELRALERQKQQQTLQLQEESKLLSQKTES--ERQKAAQRGQELSRLEAAILREKD 1650
Query: 131 ---RAEESIEDIYANIPDLPKSYIPSRLRKEINEEKEDDEQNRKA-LYAMEIKVEKDLKT 186
E ++ D++A + R+E+++E + E N + +E + KD+
Sbjct: 1651 QIYEKERTLRDLHAKVS-----------REELSQETQTRETNLSTKISILEPETGKDMSP 1699
Query: 187 GES 189
E+
Sbjct: 1700 YEA 1702
Score = 32.0 bits (71), Expect = 1.5
Identities = 31/125 (24%), Positives = 59/125 (47%), Gaps = 15/125 (12%)
Query: 2 EEAELVKGRLQAITDKRKIQEEISQKRLKIEEDKLKHQHLKKKALREKWLLDGISSGKEQ 61
EE+EL + R QA + ++Q+E+ + ++ L+ Q K + S K +
Sbjct: 1577 EESELQRARDQADQECGRLQQELRALERQKQQQTLQLQEESK-----------LLSQKTE 1625
Query: 62 EEMKKQNQQDQHQIQVLEQSILRLEKEIQDLEKAELQISTKEEAILKKLKSIERTTEDII 121
E +K Q+ Q ++ LE +ILR + +I + E+ + K + ++ S E T +
Sbjct: 1626 SERQKAAQRGQ-ELSRLEAAILREKDQIYEKERTLRDLHAK---VSREELSQETQTRETN 1681
Query: 122 RSVKV 126
S K+
Sbjct: 1682 LSTKI 1686
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.307 0.128 0.353
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,932,508
Number of Sequences: 37866
Number of extensions: 1347278
Number of successful extensions: 10538
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 203
Number of HSP's successfully gapped in prelim test: 850
Number of HSP's that attempted gapping in prelim test: 7106
Number of HSP's gapped (non-prelim): 3326
length of query: 551
length of database: 18,247,518
effective HSP length: 107
effective length of query: 444
effective length of database: 14,195,856
effective search space: 6302960064
effective search space used: 6302960064
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.