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Search of human proteins with 8922940
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|8922940 gamma-taxilin [Homo sapiens]
(528 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|8922940 gamma-taxilin [Homo sapiens] 1032 0.0
gi|28460688 taxilin [Homo sapiens] 493 e-139
gi|222537714 taxilin beta [Homo sapiens] 415 e-116
gi|14211893 lipopolysaccaride-specific response 5-like protein [... 233 4e-61
gi|140970633 hypothetical protein LOC246126 [Homo sapiens] 197 2e-50
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 80 4e-15
gi|7705415 hook homolog 1 [Homo sapiens] 80 5e-15
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 79 8e-15
gi|4885583 Rho-associated, coiled-coil containing protein kinase... 78 2e-14
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 76 7e-14
gi|31982906 cingulin-like 1 [Homo sapiens] 76 9e-14
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 75 1e-13
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 75 2e-13
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 75 2e-13
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 74 3e-13
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 74 3e-13
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 74 4e-13
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 74 4e-13
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 74 4e-13
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 74 4e-13
gi|21735548 centrosomal protein 2 [Homo sapiens] 73 6e-13
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 73 6e-13
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 72 1e-12
gi|237858621 polyamine modulated factor 1 binding protein 1 isof... 72 1e-12
gi|237858619 polyamine modulated factor 1 binding protein 1 isof... 72 1e-12
gi|55770834 centromere protein F [Homo sapiens] 72 2e-12
gi|221219020 NYD-SP11 protein [Homo sapiens] 71 3e-12
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 71 3e-12
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 70 4e-12
gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens] 70 4e-12
>gi|8922940 gamma-taxilin [Homo sapiens]
Length = 528
Score = 1032 bits (2668), Expect = 0.0
Identities = 528/528 (100%), Positives = 528/528 (100%)
Query: 1 MATRVEEAARGRGGGAEEATEAGRGGRRRSPRQKFEIGTMEEAGICGLGVKADMLCNSQS 60
MATRVEEAARGRGGGAEEATEAGRGGRRRSPRQKFEIGTMEEAGICGLGVKADMLCNSQS
Sbjct: 1 MATRVEEAARGRGGGAEEATEAGRGGRRRSPRQKFEIGTMEEAGICGLGVKADMLCNSQS 60
Query: 61 NDILQHQGSNCGGTSNKHSLEEDEGSDFITENRNLVSPAYCTQESREEIPGGEARTDPPD 120
NDILQHQGSNCGGTSNKHSLEEDEGSDFITENRNLVSPAYCTQESREEIPGGEARTDPPD
Sbjct: 61 NDILQHQGSNCGGTSNKHSLEEDEGSDFITENRNLVSPAYCTQESREEIPGGEARTDPPD 120
Query: 121 GQQDSECNRNKEKTLGKEVLLLMQALNTLSTPEEKLAALCKKYADLLEESRSVQKQMKIL 180
GQQDSECNRNKEKTLGKEVLLLMQALNTLSTPEEKLAALCKKYADLLEESRSVQKQMKIL
Sbjct: 121 GQQDSECNRNKEKTLGKEVLLLMQALNTLSTPEEKLAALCKKYADLLEESRSVQKQMKIL 180
Query: 181 QKKQAQIVKEKVHLQSEHSKAILARSKLESLCRELQRHNKTLKEENMQQAREEEERRKEA 240
QKKQAQIVKEKVHLQSEHSKAILARSKLESLCRELQRHNKTLKEENMQQAREEEERRKEA
Sbjct: 181 QKKQAQIVKEKVHLQSEHSKAILARSKLESLCRELQRHNKTLKEENMQQAREEEERRKEA 240
Query: 241 TAHFQITLDEIQAQLEQHDIHNAKLRQENIELGEKLKKLIEQYALREEHIDKVFKRKELQ 300
TAHFQITLDEIQAQLEQHDIHNAKLRQENIELGEKLKKLIEQYALREEHIDKVFKRKELQ
Sbjct: 241 TAHFQITLDEIQAQLEQHDIHNAKLRQENIELGEKLKKLIEQYALREEHIDKVFKRKELQ 300
Query: 301 QQLVDAKLQQTTQLIKEADEKHQREREFLLKEATESRHKYEQMKQQEVQLKQQLSLYMDK 360
QQLVDAKLQQTTQLIKEADEKHQREREFLLKEATESRHKYEQMKQQEVQLKQQLSLYMDK
Sbjct: 301 QQLVDAKLQQTTQLIKEADEKHQREREFLLKEATESRHKYEQMKQQEVQLKQQLSLYMDK 360
Query: 361 FEEFQTTMAKSNELFTTFRQEMEKMTKKIKKLEKETIIWRTKWENNNKALLQMAEEKTVR 420
FEEFQTTMAKSNELFTTFRQEMEKMTKKIKKLEKETIIWRTKWENNNKALLQMAEEKTVR
Sbjct: 361 FEEFQTTMAKSNELFTTFRQEMEKMTKKIKKLEKETIIWRTKWENNNKALLQMAEEKTVR 420
Query: 421 DKEYKALQIKLERLEKLCRALQTERNELNEKVEVLKEQVSIKAAIKAANRDLATPVMQPC 480
DKEYKALQIKLERLEKLCRALQTERNELNEKVEVLKEQVSIKAAIKAANRDLATPVMQPC
Sbjct: 421 DKEYKALQIKLERLEKLCRALQTERNELNEKVEVLKEQVSIKAAIKAANRDLATPVMQPC 480
Query: 481 TALDSHKELNTSSKRALGAHLEAEPKSQRSAVQKPPSTGSAPAIESVD 528
TALDSHKELNTSSKRALGAHLEAEPKSQRSAVQKPPSTGSAPAIESVD
Sbjct: 481 TALDSHKELNTSSKRALGAHLEAEPKSQRSAVQKPPSTGSAPAIESVD 528
>gi|28460688 taxilin [Homo sapiens]
Length = 546
Score = 493 bits (1269), Expect = e-139
Identities = 269/463 (58%), Positives = 338/463 (73%), Gaps = 16/463 (3%)
Query: 7 EAARGRGGGAEEATEAGRGGRRRSPRQKFEIGTMEEAGICGLGVKADMLCNSQSNDILQH 66
E A+ R A A EA G ++PR+ G G + Q DIL
Sbjct: 28 EGAQERPSQAAPAVEAEGPGSSQAPRKPE--GAQARTAQSGALRDVSEELSRQLEDILST 85
Query: 67 Q--GSNCGGTSNKHSLEEDEGSDFITENRNLVS------PAYCTQESREEIPGG----EA 114
+N GG + E + ++R V+ P +E G E
Sbjct: 86 YCVDNNQGGPGEDGAQGEPAEPEDAEKSRTYVARNGEPEPTPVVNGEKEPSKGDPNTEEI 145
Query: 115 RTDPPDGQQDSECNRNKEKT--LGKEVLLLMQALNTLSTPEEKLAALCKKYADLLEESRS 172
R G +D + K+K LGKE+ LLMQ LNTLSTPEEKLAALCKKYA+LLEE R+
Sbjct: 146 RQSDEVGDRDHRRPQEKKKAKGLGKEITLLMQTLNTLSTPEEKLAALCKKYAELLEEHRN 205
Query: 173 VQKQMKILQKKQAQIVKEKVHLQSEHSKAILARSKLESLCRELQRHNKTLKEENMQQARE 232
QKQMK+LQKKQ+Q+V+EK HL+ EHSKA+LARSKLESLCRELQRHN++LKEE +Q+ARE
Sbjct: 206 SQKQMKLLQKKQSQLVQEKDHLRGEHSKAVLARSKLESLCRELQRHNRSLKEEGVQRARE 265
Query: 233 EEERRKEATAHFQITLDEIQAQLEQHDIHNAKLRQENIELGEKLKKLIEQYALREEHIDK 292
EEE+RKE T+HFQ+TL++IQ Q+EQH+ N+KLRQEN+EL E+LKKLIEQY LREEHIDK
Sbjct: 266 EEEKRKEVTSHFQVTLNDIQLQMEQHNERNSKLRQENMELAERLKKLIEQYELREEHIDK 325
Query: 293 VFKRKELQQQLVDAKLQQTTQLIKEADEKHQREREFLLKEATESRHKYEQMKQQEVQLKQ 352
VFK K+LQQQLVDAKLQQ +++KEA+E+HQRE++FLLKEA ES+ E MKQQE LKQ
Sbjct: 326 VFKHKDLQQQLVDAKLQQAQEMLKEAEERHQREKDFLLKEAVESQRMCELMKQQETHLKQ 385
Query: 353 QLSLYMDKFEEFQTTMAKSNELFTTFRQEMEKMTKKIKKLEKETIIWRTKWENNNKALLQ 412
QL+LY +KFEEFQ T++KS+E+FTTF+QEMEKMTKKIKKLEKET ++R++WE++NKALL+
Sbjct: 386 QLALYTEKFEEFQNTLSKSSEVFTTFKQEMEKMTKKIKKLEKETTMYRSRWESSNKALLE 445
Query: 413 MAEEKTVRDKEYKALQIKLERLEKLCRALQTERNELNEKVEVL 455
MAEEKTVRDKE + LQ+K++RLEKLCRALQTERN+LN++V+ L
Sbjct: 446 MAEEKTVRDKELEGLQVKIQRLEKLCRALQTERNDLNKRVQDL 488
>gi|222537714 taxilin beta [Homo sapiens]
Length = 684
Score = 415 bits (1066), Expect = e-116
Identities = 243/507 (47%), Positives = 322/507 (63%), Gaps = 41/507 (8%)
Query: 57 NSQSNDILQHQGS---NCGGTSNKHSLEEDEGSDFITENRNLVSPAYCTQESREEIPGGE 113
N Q DI+ GS G + + E+ E ++ +N + + RE + GE
Sbjct: 60 NRQLEDIINTYGSAASTAGKEGSARASEQPENAES-PDNEDGDCEETTEEAGREPVASGE 118
Query: 114 ART-DPPDGQQDSECNRNKEKTLGKEVLLLMQALNTLSTPEEKLAALCKKYADLLEESRS 172
T P ++ + + K LGKE LLMQ LN L TPEEK L KKYA+LL+E R+
Sbjct: 119 PPTVKEPVSNKEQKLEKKILKGLGKEANLLMQNLNKLQTPEEKFDFLFKKYAELLDEHRT 178
Query: 173 VQKQMKILQKKQAQIVKEKVHLQSEHSKAILARSKLESLCRELQRHNKTLKEENMQQARE 232
QK++K+LQKKQ QI KEK LQ EHS+AILARSKLESLCRELQRHNKTLKEE +Q+ARE
Sbjct: 179 EQKKLKLLQKKQVQIQKEKDQLQGEHSRAILARSKLESLCRELQRHNKTLKEEALQRARE 238
Query: 233 EEERRKEATAHFQITLDEIQAQLEQHDIHNAKLRQENIELGEKLKKLIEQYALREEHIDK 292
EEE+RKE T+HFQ TL +IQ Q+EQ N KL QEN EL EKLK +I+QY LREEH+DK
Sbjct: 239 EEEKRKEITSHFQSTLTDIQGQIEQQSERNMKLCQENTELAEKLKSIIDQYELREEHLDK 298
Query: 293 VFKRKELQQQLVDAKLQQTTQLIKEADEKHQREREFLLKEATESRHKYEQMKQQEVQLKQ 352
+FK +ELQQ+LVDAKL+Q +++KEA+E+H+RE+E+LL +A E + + + +K+QE L+
Sbjct: 299 IFKHRELQQKLVDAKLEQAQEMMKEAEERHKREKEYLLNQAAEWKLQAKVLKEQETVLQA 358
Query: 353 QLSLYMDKFEEFQTTMAKSNELFTTFRQEMEKMTKKIKKLEKETIIWRTKWENNNKALLQ 412
QL+LY +FEEFQ+T+ KSNE+F TF+QEM+K TKK+KKLEK+T W+ ++EN NKALL
Sbjct: 359 QLTLYSGRFEEFQSTLTKSNEVFATFKQEMDKTTKKMKKLEKDTATWKARFENCNKALLD 418
Query: 413 MAEEKTVRDKEYKALQIKLERLEKLCRALQTERNELNEKV-----------------EVL 455
M EEK +R KEY+ +K+ RLE LCRALQ ERNEL++K+ E
Sbjct: 419 MIEEKALRAKEYECFVMKIGRLENLCRALQEERNELHKKIRDAEISEKDDQSQHNSDEEP 478
Query: 456 KEQVSIKAAIKA--------ANRDLAT-------PVMQPCTALDSHKELNTSSKRALGAH 500
+ VS+ I A A ++LAT P P + ++ E+ +S + A A
Sbjct: 479 ESNVSVDQEIDAEEVNSVQTAVKNLATAFMIIHHPESTPHQSKETQPEIGSSQESADAAL 538
Query: 501 LEAEP----KSQRSAVQKPPSTGSAPA 523
E E S+ S PP T A A
Sbjct: 539 KEPEQPPLIPSRDSESPLPPLTPQAEA 565
>gi|14211893 lipopolysaccaride-specific response 5-like protein
[Homo sapiens]
Length = 181
Score = 233 bits (593), Expect = 4e-61
Identities = 124/185 (67%), Positives = 141/185 (76%), Gaps = 6/185 (3%)
Query: 343 MKQQEVQLKQQLSLYMDKFEEFQTTMAKSNELFTTFRQEMEKMTKKIKKLEKETIIWRTK 402
MKQ+E QLK+QL LYMDKFEEFQTTMAK+NELFT F+QE EK+TKKIKKLEKE +IW TK
Sbjct: 1 MKQEEAQLKEQLFLYMDKFEEFQTTMAKTNELFTAFKQETEKLTKKIKKLEKEMVIWYTK 60
Query: 403 WENNNKALLQMAEEKTVRDKEYKALQIKLERLEKLCRALQTERNELNEKVEVLKEQVSIK 462
WENNN LLQMAEEKT+RDK YK QIKLERLEKL +ALQ ERNEL+EK+ +LK QVS
Sbjct: 61 WENNNTTLLQMAEEKTIRDKNYKVFQIKLERLEKLYKALQIERNELSEKLGILKGQVS-- 118
Query: 463 AAIKAANRDLATPVMQPCTALDSHKELNTSSKRALGAHLEAEPK--SQRSAVQKPPSTGS 520
+K A+ DLA PV C LDS LNTSSKRA G HLEA+PK ++ K STGS
Sbjct: 119 --VKVADVDLAVPVTHSCADLDSSNMLNTSSKRAPGVHLEADPKGMNEVKCYSKALSTGS 176
Query: 521 APAIE 525
I+
Sbjct: 177 PLGID 181
>gi|140970633 hypothetical protein LOC246126 [Homo sapiens]
Length = 131
Score = 197 bits (501), Expect = 2e-50
Identities = 97/127 (76%), Positives = 107/127 (84%), Gaps = 2/127 (1%)
Query: 40 MEEAGICGLGVKADMLCNSQSNDILQHQGSNCGGTSNKHSLEEDEGSDFITENRNLVSPA 99
MEEAG+CGL KADMLCNS+S+DILQHQ SNC TSNKH LE++EG DFIT+NR+ VSP
Sbjct: 1 MEEAGLCGLREKADMLCNSESHDILQHQDSNCSATSNKHLLEDEEGRDFITKNRSWVSPV 60
Query: 100 YCTQESREEIPGGEARTDPPDGQQDSECNRNKEKTLGKEVLLLMQALNTLSTPEEKLAAL 159
+CTQESR E+P E PP GQQ +CNRNKEK LGKEVLLLMQALNTLSTPEEKLAAL
Sbjct: 61 HCTQESRRELP--EQEVAPPSGQQALQCNRNKEKVLGKEVLLLMQALNTLSTPEEKLAAL 118
Query: 160 CKKYADL 166
CKKYADL
Sbjct: 119 CKKYADL 125
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 80.5 bits (197), Expect = 4e-15
Identities = 86/357 (24%), Positives = 162/357 (45%), Gaps = 46/357 (12%)
Query: 143 MQALNTLSTPEEKLAALCKKYADLLEESRSVQKQMKILQKKQAQIVKEKVHLQSEHSKAI 202
++ L +S EE++ A ++ + E+ + + ++ ++ Q+Q++ EK+ LQ +
Sbjct: 834 VKPLLQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAET 893
Query: 203 LARSKLESLCRELQRHNKTLKE---ENMQQAREEEERRKEATAH---FQITLDEIQAQLE 256
++ E L L + L+E + + EEEER + A Q + E++ QLE
Sbjct: 894 ELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLE 953
Query: 257 QHDIHNAKLRQENIELGEKLKKLIEQYALREEHIDKVFKRKELQQQLVDAKLQQTTQLIK 316
+ + KL+ E + KLKKL E+ + E+ K+ K K+L L D + TT L +
Sbjct: 954 EEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKL---LEDRIAEFTTNLTE 1010
Query: 317 EADE---------KHQ----------REREFLLKEATESRHKYE-----------QMKQQ 346
E ++ KH+ R E +E ++R K E +++ Q
Sbjct: 1011 EEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQ 1070
Query: 347 EVQLKQQLSLYMDKFEEFQTTMAKSNELFTTFRQEMEKMTKKIKKLEKETIIWRTKWENN 406
+LK QL+ K EE Q +A+ E + KKI++LE + + E+
Sbjct: 1071 IAELKMQLA---KKEEELQAALARVEE----EAAQKNMALKKIRELESQISELQEDLESE 1123
Query: 407 NKALLQMAEEKTVRDKEYKALQIKLERLEKLCRALQTERNELNEKVEVLKEQVSIKA 463
+ + ++K +E +AL+ +LE A Q R++ ++V +LK+ + +A
Sbjct: 1124 RASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEA 1180
Score = 58.9 bits (141), Expect = 1e-08
Identities = 71/352 (20%), Positives = 148/352 (42%), Gaps = 33/352 (9%)
Query: 122 QQDSECNRNKEKTLGKEVLLLMQALNTLSTPEEKLAALCKKYADLLE-----ESRSVQKQ 176
+Q E + + K G L Q + E L KK +L E + QK
Sbjct: 1041 KQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKN 1100
Query: 177 M--KILQKKQAQIVKEKVHLQSEHSKAILARSKLESLCRELQRHNKTLKEENMQQAREEE 234
M K +++ ++QI + + L+SE + A + L EL+ KT E+ + ++
Sbjct: 1101 MALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEAL-KTELEDTLDSTAAQQ 1159
Query: 235 ERRKEATAHFQITLDEIQAQLEQHDIHNAKLRQENIELGEKLKKLIEQYALREEHIDKVF 294
E R + I ++ + + H+ ++RQ++ + E+L + +E
Sbjct: 1160 ELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLE------------- 1206
Query: 295 KRKELQQQLVDAKLQQTTQLIKEADEKHQREREFLLKEATESRHKYEQMKQ--QEVQLK- 351
Q + V A L++ Q ++ + E + LL+ +S HK ++++ QE+Q+K
Sbjct: 1207 -----QTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKF 1261
Query: 352 ----QQLSLYMDKFEEFQTTMAKSNELFTTFRQEMEKMTKKIKKLEKETIIWRTKWENNN 407
+ + DK + Q + L + + K+TK LE + + + N
Sbjct: 1262 NEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEEN 1321
Query: 408 KALLQMAEEKTVRDKEYKALQIKLERLEKLCRALQTERNELNEKVEVLKEQV 459
+ L ++ + + E + + +LE E+ L+ + L+ +V +K+++
Sbjct: 1322 RQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKM 1373
Score = 56.2 bits (134), Expect = 7e-08
Identities = 104/480 (21%), Positives = 191/480 (39%), Gaps = 99/480 (20%)
Query: 113 EARTDPPDGQQDSECNRNKEKTLGKEVLLLMQALNTLSTPE--EKLAALCKKYADLLEES 170
E D QQ+ R +E + K+ L + E +K + ++ A+ LE++
Sbjct: 1149 EDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQT 1208
Query: 171 RSV----QKQMKILQKKQAQIVKE-KVHLQ----SEHSKAILARSKLESLCRELQRHNKT 221
+ V +K + L+ ++ ++ E KV LQ SEH R K+E+ +ELQ
Sbjct: 1209 KRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHK-----RKKVEAQLQELQ----- 1258
Query: 222 LKEENMQQAREEEERRKEATAHFQITLDEIQAQLEQHDIHNAKLRQENIELGEKLKKLIE 281
+K ++ R E + Q+ LD + L Q D ++KL ++ L +L+
Sbjct: 1259 VKFNEGERVRTE---LADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDT-- 1313
Query: 282 QYALREEHIDKVFKRKELQQQLVDAKLQQTTQLIKEADEKHQREREF---------LLKE 332
Q L+EE+ K+ +L+Q + D K QL +E + KH E++ + K+
Sbjct: 1314 QELLQEENRQKLSLSTKLKQ-VEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKK 1372
Query: 333 ATESRHKYEQMKQQEVQLKQQLSLYMDKFEEFQTTMAKSNELFTTFRQEMEKMTKKIKKL 392
+S E ++ + +L++ L + EE K + T +QE++ + +
Sbjct: 1373 MEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQ 1432
Query: 393 EKETIIWRTKWENNNKALLQMAEEKTV---------------RDKEYKALQI-------- 429
+ K + ++ L AEEKT+ R+KE KAL +
Sbjct: 1433 RQSACNLEKKQKKFDQLL---AEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAM 1489
Query: 430 ----KLERL-------------------------EKLCRALQTERNELNEKVEVLKEQVS 460
+LERL EK RAL+ + E+ ++E L++++
Sbjct: 1490 EQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQ 1549
Query: 461 --------IKAAIKAANRDLATPVMQPCTALDSHKELNTSSKRALGAHLEAEPKSQRSAV 512
++ ++A + + K+ R + A LE E K + AV
Sbjct: 1550 ATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAV 1609
Score = 48.5 bits (114), Expect = 1e-05
Identities = 47/274 (17%), Positives = 117/274 (42%), Gaps = 21/274 (7%)
Query: 123 QDSECNRNKEKTLGKEVLLLMQALNTLSTPEEKLAALCKKYADLLEESRSVQKQMKILQK 182
Q +C R + T +L QA E+KL ++ + L EE + ++ + Q+
Sbjct: 1646 QMKDCMRELDDTRASREEILAQAKEN----EKKLKSMEAEMIQLQEELAAAERAKRQAQQ 1701
Query: 183 KQAQIVKEKVHLQSEHSKAILARSKLESLCRELQRHNKTLKEENMQQAREEEERRKEATA 242
++ ++ E + + + A+ + +LE+ +L EE +++ + E +
Sbjct: 1702 ERDELADEIANSSGKGALALEEKRRLEARIAQL--------EEELEEEQGNTELINDRLK 1753
Query: 243 HFQITLDEIQAQLEQHDIHNAKLRQENIELGEKLKKLIEQYALREEHIDKVFKRK-ELQQ 301
+ +D+I L H Q+N ++L++ ++ ++ + ++ K K +
Sbjct: 1754 KANLQIDQINTDLNLERSH----AQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASI 1809
Query: 302 QLVDAKLQQTTQLIKEADEKHQREREFLLKEATESRHKYEQMKQQEVQLKQQLSLYMDKF 361
++AK+ Q ++E + +ER+ K+ + K + + Q ++ Y D+
Sbjct: 1810 TALEAKIAQ----LEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQA 1865
Query: 362 EEFQTTMAKSNELFTTFRQEMEKMTKKIKKLEKE 395
++ T + + +E ++ +KL++E
Sbjct: 1866 DKASTRLKQLKRQLEEAEEEAQRANASRRKLQRE 1899
>gi|7705415 hook homolog 1 [Homo sapiens]
Length = 728
Score = 80.1 bits (196), Expect = 5e-15
Identities = 88/374 (23%), Positives = 162/374 (43%), Gaps = 58/374 (15%)
Query: 128 NRNKEKT-LGKEVLLLMQALNTL---STPEEKLAALCKKYADLLEESRSVQKQMKILQKK 183
+RN E T L +E L ++ L S KL + + Y L++ ++KQ+K LQ+
Sbjct: 287 HRNDELTSLAEETRALKDEIDVLRATSDKANKLESTVEIYRQKLQDLNDLRKQVKTLQET 346
Query: 184 QAQIVKEKVHLQSEHSKAILARSKLESLCRELQRHNKTLKEEN---------MQQAREEE 234
+ V L+ E KA AR++LE+ R++Q + L E+ M++ E+
Sbjct: 347 NMMYMHNTVSLEEELKKANAARTQLETYKRQVQDLHVKLSSESKRADTLAFEMKRLEEKH 406
Query: 235 E---RRKEATAHFQITLDEIQAQLEQHDIHNAKLRQENIELGEKLKKLIEQYA------- 284
E + KE + TL E +L + L Q + + + L +
Sbjct: 407 EALLKEKERLIEQRDTLKETNEELRCSQVQQDHLNQTDASATKSYENLAAEIMPVEYREV 466
Query: 285 -LREEHIDKVFKRK----------ELQQQLVDA-----KLQQTTQLIKEADEKHQREREF 328
+R +H +K+ + + ELQ+QL +L+ +L KE + Q++ E
Sbjct: 467 FIRLQHENKMLRLQQEGSENERIEELQEQLEQKHRKMNELETEQRLSKERIRELQQQIED 526
Query: 329 LLKEATESRHKYEQMKQQEVQLKQQLSLYMDKFEEFQTTMAKSNELFTTFRQEMEKMTKK 388
L K E K E + +LKQ+L +M+K E + K EL + ++ + +K
Sbjct: 527 LQKSLQEQGSKSEG--ESSSKLKQKLEAHMEKLTEVHEELQKKQELIEDLQPDINQNVQK 584
Query: 389 IKKLEKETIIWRTKWENNNKALLQMAEEKTVRDKEYKALQIKLERLEKLCRALQTERNEL 448
I +LE AL + E+ ++ YK + LE+ + + L + N
Sbjct: 585 INELE--------------AALQKKDEDMKAMEERYK---MYLEKARNVIKTLDPKLNPA 627
Query: 449 NEKVEVLKEQVSIK 462
+ ++ +L++Q++ K
Sbjct: 628 SAEIMLLRKQLAEK 641
Score = 58.9 bits (141), Expect = 1e-08
Identities = 74/362 (20%), Positives = 152/362 (41%), Gaps = 62/362 (17%)
Query: 119 PDGQQDSECNRNKEKTLGKEVLLLMQALNTLSTPEEKLAALCKKYADLLEESRSVQKQMK 178
PD Q +EC+ E LG+ + L++ A C+K + ++ ++++ ++
Sbjct: 103 PDLNQITECSDPVE--LGRLLQLILGC-----------AINCEKKQEHIQNIMTLEESVQ 149
Query: 179 ILQKKQAQIVKEKVHLQSEHSKAILARSKLESLCRELQRHNKTLKEENMQQAREEEERRK 238
+ Q + K L S + A+ EL++ K EE + E+EE R+
Sbjct: 150 HVVMTAIQELMSKEILSSPPNDAV----------GELEQQLKRALEELQEALAEKEELRQ 199
Query: 239 EATAHFQITLDEIQAQLEQHDIHNAKLRQENIELGEKLKKLIEQYALREEHIDKVFKRKE 298
+E+ Q+ L EN + EKL +L + + + V +K
Sbjct: 200 RC--------EELDMQVTTLQDEKNSLVSENEMMNEKLDQLDGSF----DDPNTVVAKKY 247
Query: 299 LQQQLVDAKLQQTTQLIKEADEKHQREREFLLKEATESRHKYEQMKQQEVQLKQQLSLYM 358
QL +LQ+ ++ A + ++ E L K+ E +H+ +++ L ++
Sbjct: 248 FHAQLQLEQLQEENFRLEAAKDDYRVHCEELEKQLIEFQHRNDEL----TSLAEETRALK 303
Query: 359 DKFEEFQTTMAKSNELFTTFR------QEMEKMTKKIKKLEKETIIW------------- 399
D+ + + T K+N+L +T Q++ + K++K L++ +++
Sbjct: 304 DEIDVLRATSDKANKLESTVEIYRQKLQDLNDLRKQVKTLQETNMMYMHNTVSLEEELKK 363
Query: 400 ----RTKWENNNKALLQMAEEKTVRDKEYKALQIKLERLEKLCRALQTERNELNEKVEVL 455
RT+ E + + + + + K L +++RLE+ AL E+ L E+ + L
Sbjct: 364 ANAARTQLETYKRQVQDLHVKLSSESKRADTLAFEMKRLEEKHEALLKEKERLIEQRDTL 423
Query: 456 KE 457
KE
Sbjct: 424 KE 425
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 79.3 bits (194), Expect = 8e-15
Identities = 84/380 (22%), Positives = 182/380 (47%), Gaps = 46/380 (12%)
Query: 139 VLLLMQALNTLSTPEEKLAALCKKYADLLEESRSVQKQMKILQKKQAQIVKEK------- 191
V ++ L ++ EE+L A ++ + E+ V+ +++ +++K Q+++EK
Sbjct: 837 VFTKVKPLLQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQL 896
Query: 192 -----VHLQSEHSKAILARSK--LESLCRELQRHNKTLKEENMQQAREEEERRKEATAHF 244
+ ++E +A LA K LE + +L+ ++ +EE Q + E+++ +A H
Sbjct: 897 QAETELFAEAEEMRARLAAKKQELEEILHDLE--SRVEEEEERNQILQNEKKKMQA--HI 952
Query: 245 QITLDEIQAQLEQHDIHNAKLRQENIELGEKLKKLIEQYALREEHIDKVFKRKELQQQLV 304
Q +++ QL++ + KL+ E + K+KK+ E+ L E+ K K K+L +
Sbjct: 953 Q----DLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLME--- 1005
Query: 305 DAKLQQTTQLIKEADE-----KHQREREFLLKEATESRHKYEQMKQQEVQLKQQL-SLYM 358
D + ++QL +E ++ K + ++E ++ + E K E+ +Q+ + K++L
Sbjct: 1006 DRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETT 1065
Query: 359 DKFEEFQTTMAKSNELFTTFRQEMEKMTKKIKKLEKETIIWRTKWENNNKALLQMAEEKT 418
D ++ A+ +EL ++ E++ + + + ET+ + N AL K
Sbjct: 1066 DLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETL-------HKNNAL------KV 1112
Query: 419 VRDKEYKALQIKLE-RLEKLCR-ALQTERNELNEKVEVLKEQVSIKAAIKAANRDLATPV 476
VR+ + + +++ + EK R + ++ +L+E++E LK ++ AA ++L T
Sbjct: 1113 VRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKR 1172
Query: 477 MQPCTALDSHKELNTSSKRA 496
Q L E T + A
Sbjct: 1173 EQEVAELKKALEEETKNHEA 1192
Score = 62.8 bits (151), Expect = 8e-10
Identities = 95/444 (21%), Positives = 187/444 (42%), Gaps = 66/444 (14%)
Query: 74 TSNKHSLEEDEGSDFITENRNLVSPAYCTQESREEIPGGE----ARTDPPDGQQDSECNR 129
T N+ E D+ + + R + S Q+ +++ E AR + ++E
Sbjct: 1421 TKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEARE 1480
Query: 130 NKEKTLGKEVLLLMQALNTLSTPEEKLAALCKKYADLLEESRSVQKQMKILQKKQ----- 184
+ K L L +AL E + L DL+ V K + L+K +
Sbjct: 1481 KETKALSL-ARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQ 1539
Query: 185 ------AQIVKEKVHLQSEHSKAILARSKLESLCRELQRHNKTLKEEN-------MQQAR 231
Q+ + + LQ+ + ++++ + +R +T E+N ++Q R
Sbjct: 1540 QVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVR 1599
Query: 232 E-----EEERRKEATA-----HFQITLDEIQAQLEQHDIHNAKLRQENIELGEKLKKLIE 281
E E+ER++ A A +I L +++AQ+E + K R E I+ KL+ ++
Sbjct: 1600 ELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAAN----KARDEVIKQLRKLQAQMK 1655
Query: 282 QYALREEHI----DKVF--------KRKELQQQLVDAKLQQTTQLIKEADEKHQREREFL 329
Y E D++F K K L+ +++ +LQ+ + A ++ER+ L
Sbjct: 1656 DYQRELEEARASRDEIFAQSKESEKKLKSLEAEIL--QLQEELASSERARRHAEQERDEL 1713
Query: 330 LKEATESRHKYEQMKQQEVQLKQQLSLYMDKFEEFQTTMAKSNELFTTFRQEMEKMTKKI 389
E T S + ++ +L+ +++ ++ EE Q+ M N+ F K T ++
Sbjct: 1714 ADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRF-------RKTTLQV 1766
Query: 390 KKLEKETIIWRTKWENNNKALLQMAEEKTVRDKEYKALQIKLERLEKLCRA-LQTERNEL 448
L E R+ + ++ A Q+ +++ K L+ KL+ LE ++ + + L
Sbjct: 1767 DTLNAELAAERSAAQKSDNARQQL-------ERQNKELKAKLQELEGAVKSKFKATISAL 1819
Query: 449 NEKVEVLKEQVSIKAAIKAANRDL 472
K+ L+EQ+ +A +AA L
Sbjct: 1820 EAKIGQLEEQLEQEAKERAAANKL 1843
Score = 58.5 bits (140), Expect = 1e-08
Identities = 86/384 (22%), Positives = 160/384 (41%), Gaps = 57/384 (14%)
Query: 126 ECNRNKEKTLGKEVLLLMQALNTLSTPEEKLAALCKKYADLL-------EESRSVQKQMK 178
E + K K G+ L Q + +E L KK +L +E+ +K
Sbjct: 1052 ELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALK 1111
Query: 179 ILQKKQAQIVKEKVHLQSEHSKAILARSKLESLCREL----------------QRHNKTL 222
++++ QAQI + + +SE + A + L EL Q+ +T
Sbjct: 1112 VVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTK 1171
Query: 223 KEEN---MQQAREEEERRKEATAH-----FQITLDEIQAQLEQHDIHNAKLRQENIELGE 274
+E+ +++A EEE + EA L+E+ QLEQ A L + L
Sbjct: 1172 REQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLET 1231
Query: 275 KLKKL-IEQYALREEHIDKVFKRKEL--QQQLVDAKLQQTTQLIKEADEKHQRER----- 326
K+L E L++ + KRK+L Q Q + AK+ + +L E EK + +
Sbjct: 1232 DNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDN 1291
Query: 327 -EFLLKEATESRHKY--------------EQMKQQEVQLKQQLSLYMDKFEEFQTTMAKS 371
LL+EA + K+ +++ Q+E + K LS + + EE + ++ +
Sbjct: 1292 VSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQ 1351
Query: 372 NELFTTFRQEMEKMTKKIKKLEKETIIWRTKWENNNKALLQMAEEKTVRDKEYKALQIKL 431
E R+ +E K++ L+ + + K +++ + + E K K+ +AL +L
Sbjct: 1352 QEEEEEARKNLE---KQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRL 1408
Query: 432 ERLEKLCRALQTERNELNEKVEVL 455
E L+ +N L ++++ L
Sbjct: 1409 EEKALAYDKLEKTKNRLQQELDDL 1432
Score = 53.9 bits (128), Expect = 4e-07
Identities = 54/252 (21%), Positives = 107/252 (42%), Gaps = 19/252 (7%)
Query: 106 REEIPGGEARTDPPDGQQDSECNRNKEKTLGKEVLLLMQALNTLSTPEEKLAALCKKYAD 165
+EE+ E + ++D + GK LL ++ L + A
Sbjct: 1693 QEELASSERARRHAEQERDELADEITNSASGKSALL------------DEKRRLEARIAQ 1740
Query: 166 LLEESRSVQKQMKILQKKQAQIVKEKVHLQSEHSKAILARSKLESLCRELQRHNKTLKEE 225
L EE Q M++L + + + L +E + A K ++ ++L+R NK LK +
Sbjct: 1741 LEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAK 1800
Query: 226 NMQQAREEEERRKEATAHFQITLDEIQAQLEQHDIHNAKLRQENIELGEKLKKLIEQYAL 285
+ + + K + + + +++ QLEQ A + +KLK++ Q
Sbjct: 1801 LQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVED 1860
Query: 286 REEHIDKVFKRKELQQQLVDAKLQQTTQLIKEADEKHQR---EREFLLKEATESRHKYEQ 342
H D+ KE Q + +A+++Q + ++EA+E+ R R L +E ++ E
Sbjct: 1861 ERRHADQY---KE-QMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEG 1916
Query: 343 MKQQEVQLKQQL 354
+ ++ LK +L
Sbjct: 1917 LSREVSTLKNRL 1928
Score = 51.6 bits (122), Expect = 2e-06
Identities = 97/445 (21%), Positives = 182/445 (40%), Gaps = 94/445 (21%)
Query: 122 QQDSECNRNKEKTLGKEVLLLMQALNTLSTPEEKLAA-LCKKYADLLEESRSVQKQMKIL 180
QQ + +K K L +V Q L+ + ++L L +K + L E +V ++
Sbjct: 1244 QQVKAESEHKRKKLDAQV----QELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEA 1299
Query: 181 QKKQAQIVKEKVHLQSE--HSKAILARS-----KLESLCRELQRHNKTLKEENMQQAREE 233
+KK + K+ L+S+ ++ +L L S R+L+ +L+E Q EE
Sbjct: 1300 EKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQE----QQEEE 1355
Query: 234 EERRKEAT----------AHFQITLDEIQAQLEQHDIHNAKLRQENIELGEKLKKLIEQY 283
EE RK A + +D+ +E + KL ++ E L + +E+
Sbjct: 1356 EEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKD----AEALSQRLEEK 1411
Query: 284 ALREEHIDKVFKRKELQQQLVDA----------------KLQQTTQLIKE--------AD 319
AL + ++K R LQQ+L D K ++ QL+ E A+
Sbjct: 1412 ALAYDKLEKTKNR--LQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAE 1469
Query: 320 EKHQREREFLLKEAT---------ESRHKYEQMKQQEVQLKQQLSLYMDKFEEFQTTMAK 370
E+ + E E KE E+ E+ ++Q QL+ + M ++ + +
Sbjct: 1470 ERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHE 1529
Query: 371 SNELFTTFRQEMEKMTKKIKKLEKETIIWRTKWENNNKALLQMAEEKTVRDKEYKALQIK 430
+ Q++E+M ++++LE E LQ E+ +R L++
Sbjct: 1530 LEKSKRALEQQVEEMRTQLEELEDE---------------LQATEDAKLR------LEVN 1568
Query: 431 LERLE-KLCRALQTERNELNEKVEVLKEQVSIKAAIKAANRDLATPVMQPCTALDSHKEL 489
++ ++ + R LQT + EK +L +QV + +L Q A+ S K++
Sbjct: 1569 MQAMKAQFERDLQTRDEQNEEKKRLLIKQV------RELEAELEDERKQRALAVASKKKM 1622
Query: 490 NTSSKRALGAHLEAEPKSQRSAVQK 514
K L A +EA K++ +++
Sbjct: 1623 EIDLK-DLEAQIEAANKARDEVIKQ 1646
>gi|4885583 Rho-associated, coiled-coil containing protein kinase 1
[Homo sapiens]
Length = 1354
Score = 77.8 bits (190), Expect = 2e-14
Identities = 102/408 (25%), Positives = 171/408 (41%), Gaps = 62/408 (15%)
Query: 124 DSECN--RNKEKTLG---KEVLLLMQALNTLSTPEEK-------LAALCKKYADLLEESR 171
D E N RN E T+ KE +LL +N E+ + D LE+ +
Sbjct: 468 DEEGNQRRNLESTVSQIEKEKMLLQHRINEYQRKAEQENEKRRNVENEVSTLKDQLEDLK 527
Query: 172 SVQKQMKILQKKQAQIVKE--------------KVHLQSEHSKAILARSKLESLCRELQR 217
V + ++ +K +Q+ K+ V L+ H++ + S+LESL RELQ
Sbjct: 528 KVSQNSQLANEKLSQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSISQLESLNRELQE 587
Query: 218 HNKTLKEENMQ--------QAREEEERRKEATAHFQITLDEIQAQLE--QHDIHNAKLRQ 267
N+ L+ Q QA E ERR H + ++QA++ Q ++ + K
Sbjct: 588 RNRILENSKSQTDKDYYQLQAILEAERRDR--GHDSEMIGDLQARITSLQEEVKHLKHNL 645
Query: 268 ENIELGEKLKKLIEQYALREEH---IDKVFKRKELQQQL---------VDAKLQQTTQLI 315
E +E K + + ++ +E++ ID +K K LQQ+L A+L Q I
Sbjct: 646 EKVEGERKEAQDMLNHSEKEKNNLEIDLNYKLKSLQQRLEQEVNEHKVTKARLTDKHQSI 705
Query: 316 KEADEKHQREREFLLKEATESRHKYE----QMKQQEVQLKQQLSLYMDKFEEFQTTMAKS 371
+EA E E LKE E+R K E Q+++Q L L K E +
Sbjct: 706 EEAKSVAMCEMEKKLKEEREAREKAENRVVQIEKQCSMLDVDLKQSQQKLEHLTGNKERM 765
Query: 372 NELFTTFRQEMEKMTKKIKKLEKETIIWRTKWENNNKALLQMAEEKTVRDKEYKALQIKL 431
+ ++E+ + K L+ E + +N QM +E + + L+ +L
Sbjct: 766 EDEVKNLTLQLEQESNKRLLLQNELKTQAFEADNLKGLEKQMKQEINTLLEAKRLLEFEL 825
Query: 432 ERLEKLCRALQTERNELNEKVE-------VLKEQV-SIKAAIKAANRD 471
+L K R + + EL +++E + K QV +K I+ NR+
Sbjct: 826 AQLTKQYRGNEGQMRELQDQLEAEQYFSTLYKTQVKELKEEIEEKNRE 873
Score = 59.3 bits (142), Expect = 8e-09
Identities = 98/477 (20%), Positives = 194/477 (40%), Gaps = 69/477 (14%)
Query: 74 TSNKHSLEEDEGSD--------FITENRNLVSPAYCTQESREEIPGGEARTDPPDGQQDS 125
TSN LEED+G + F+ V Y + +R + + +P D + S
Sbjct: 365 TSNFDDLEEDKGEEETFPIPKAFVGNQLPFVGFTYYS--NRRYL----SSANPNDNRTSS 418
Query: 126 ECNRNKEKTLGKEVLLLMQALNTLSTPEEKLAALCK----KYADLLEESRSVQKQMKILQ 181
+++ +++L K + L + L+ ++++ C+ K +++E Q + L+
Sbjct: 419 NADKSLQESLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDKIMKELDEEGNQRRNLE 478
Query: 182 KKQAQIVKEKVHLQSEHSKAILARSKLESLCRELQRHNKTLKE--ENMQQAREEEERRKE 239
+QI KEK+ LQ ++ + R ++ TLK+ E++++ + + E
Sbjct: 479 STVSQIEKEKMLLQHRINEYQRKAEQENEKRRNVENEVSTLKDQLEDLKKVSQNSQLANE 538
Query: 240 ATAHFQITLDEIQAQLEQHDIHNAKLRQENIELGEKL-------KKLIEQYALREEHIDK 292
+ Q L+E L +LR+ + E+ + + ++L E+ + E +
Sbjct: 539 KLSQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSISQLESLNRELQERNRILENSKSQ 598
Query: 293 VFKRKELQQQLVDAK--------------------LQQTTQLIKEADEKHQREREFLLKE 332
K Q +++A+ LQ+ + +K EK + ER KE
Sbjct: 599 TDKDYYQLQAILEAERRDRGHDSEMIGDLQARITSLQEEVKHLKHNLEKVEGER----KE 654
Query: 333 ATES-RHKYEQMKQQEVQLKQQLSLYMDKFE----EFQTTMAKSNELFTTFRQEMEKMTK 387
A + H ++ E+ L +L + E E + T A+ + + +
Sbjct: 655 AQDMLNHSEKEKNNLEIDLNYKLKSLQQRLEQEVNEHKVTKARLTDKHQSIEEAKSVAMC 714
Query: 388 KIKKLEKETIIWRTKWENNNKALLQMAEEKTVRDKEYKALQIKLERLEKLCRALQTERNE 447
+++K KE R K EN ++Q+ ++ ++ D + K Q KLE L ++ E
Sbjct: 715 EMEKKLKEEREAREKAENR---VVQIEKQCSMLDVDLKQSQQKLEHLTGNKERMEDEVKN 771
Query: 448 LNEKVEVLKEQVSIKAAIKAANRDLATPVMQPCTALDSHKELNTSSKRALGAHLEAE 504
L ++ EQ S K + +L T + D+ K L K+ + LEA+
Sbjct: 772 LTLQL----EQESNKRLL--LQNELKTQAFE----ADNLKGLEKQMKQEINTLLEAK 818
Score = 55.8 bits (133), Expect = 9e-08
Identities = 71/303 (23%), Positives = 138/303 (45%), Gaps = 39/303 (12%)
Query: 132 EKTLGKEVLLLMQALNTLSTPEEKLAALCKKYADLLEESRSVQKQMKI------LQKKQA 185
EK + +E+ L++A L E +LA L K+Y + R +Q Q++ L K Q
Sbjct: 804 EKQMKQEINTLLEAKRLL---EFELAQLTKQYRGNEGQMRELQDQLEAEQYFSTLYKTQV 860
Query: 186 QIVKEKVHLQSEHS--KAILARSKLESLCRELQRHNKTLKEENMQQAREEE-------ER 236
+ +KE++ ++ + K +++ E+L +L + E + + EE E
Sbjct: 861 KELKEEIEEKNRENLKKIQELQNEKETLATQLDLAETKAESEQLARGLLEEQYFELTQES 920
Query: 237 RKEATAHFQITLDEIQ--AQLEQHDIHNAK----LRQENIELGEKLKKLIEQYAL-REEH 289
+K A+ + Q D+ ++LE+ + K LR+EN EL EK+KK E+Y L +EE
Sbjct: 921 KKAASRNRQEITDKDHTVSRLEEANSMLTKDIEILRRENEELTEKMKKAEEEYKLEKEEE 980
Query: 290 IDKV----FKRKELQQQLVDAKLQQTTQLIKEADEKHQRER---EFLLKEATESRHKYEQ 342
I + K ++ L + + +++ D K R++ + L K+ E+R +
Sbjct: 981 ISNLKAAFEKNINTERTLKTQAVNKLAEIMNRKDFKIDRKKANTQDLRKKEKENRKLQLE 1040
Query: 343 MKQQEVQLKQQLSLYMDKFEEFQTTM----AKSNEL---FTTFRQEMEKMTKKIKKLEKE 395
+ Q+ + Q + + + + Q + A NEL + ++E++ K+ L
Sbjct: 1041 LNQEREKFNQMVVKHQKELNDMQAQLVEECAHRNELQMQLASKESDIEQLRAKLLDLSDS 1100
Query: 396 TII 398
T +
Sbjct: 1101 TSV 1103
Score = 50.4 bits (119), Expect = 4e-06
Identities = 73/322 (22%), Positives = 133/322 (41%), Gaps = 42/322 (13%)
Query: 161 KKYADLLEESRSVQKQMKILQKKQAQIVKEKVHLQSEHSKAILARSKLESLCRELQRHNK 220
+K L ++ ++K L + Q +++ LQ+E L+ L +++++
Sbjct: 753 QKLEHLTGNKERMEDEVKNLTLQLEQESNKRLLLQNELKTQAFEADNLKGLEKQMKQEIN 812
Query: 221 TLKEENMQQAREEEERRKEATAHFQITLDEIQAQLEQHDIHNAKLRQENIELGEKLKKLI 280
TL E E + K+ + + + E+Q QLE + + + EL E+++
Sbjct: 813 TLLEAKRLLEFELAQLTKQYRGN-EGQMRELQDQLEAEQYFSTLYKTQVKELKEEIE--- 868
Query: 281 EQYALREEHIDKVFKRKELQQQLVDAKLQQTTQLIKEADEKHQREREFLLK---EATESR 337
E++ + + K +ELQ + L L + E Q R L + E T+
Sbjct: 869 ------EKNRENLKKIQELQNE--KETLATQLDLAETKAESEQLARGLLEEQYFELTQES 920
Query: 338 HKYEQMKQQEVQLKQQLSLYMDKFEEFQTTMAKSNELFTTFRQEMEKMTKKIKKLEKETI 397
K +QE+ K + + EE + + K E+ R+E E++T+K+KK E+E
Sbjct: 921 KKAASRNRQEITDKDHT---VSRLEEANSMLTKDIEIL---RRENEELTEKMKKAEEEYK 974
Query: 398 IWRTKWENNNKA-------------------LLQMAEEKTVRDKEYKALQIKLERLEKLC 438
+ + + +N KA L ++ K + KA L + EK
Sbjct: 975 LEKEEEISNLKAAFEKNINTERTLKTQAVNKLAEIMNRKDFKIDRKKANTQDLRKKEKEN 1034
Query: 439 RALQTERNELNEKVE--VLKEQ 458
R LQ E N+ EK V+K Q
Sbjct: 1035 RKLQLELNQEREKFNQMVVKHQ 1056
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 76.3 bits (186), Expect = 7e-14
Identities = 98/455 (21%), Positives = 192/455 (42%), Gaps = 60/455 (13%)
Query: 59 QSNDILQHQGSNCGGTSNKHSLEEDEGSDFITENRNLVSPAYCTQESREEIPGGEARTDP 118
+ N++LQ + +N T K E E S+ ENR L + ++ E
Sbjct: 639 KENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQ 698
Query: 119 PDGQQDSECNRNKE----------------KTLGKEVLLLMQALNTLSTPEEKLAALCKK 162
D +++ E RN E K L E L + L L +K L
Sbjct: 699 LD-EENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVS 757
Query: 163 YADLLEESRSVQKQMKILQKKQAQIVKEKVHLQSEHS--KAILARSKLES-LCRELQRHN 219
Y L E++ +QK ++ KK Q+ E L+ E+ + L K+ S +L++ N
Sbjct: 758 YQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKEN 817
Query: 220 KTLKEENMQQAREEEERRKEATAHFQITLDEIQAQLEQHDIHNAKLRQENIELGEKLKKL 279
K+L++E Q +++++ KE + + LE++++ L +EN L +++ +
Sbjct: 818 KSLEQETSQLEKDKKQLEKE-NKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEI-GI 875
Query: 280 IEQYALREEHIDKVFKR------------KELQQQLVDAKLQQTTQLIKEADE-KHQRER 326
++ +R + ++K K L++ LV KL +T Q+ + ++ H+ E+
Sbjct: 876 YKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKL-KTQQMNNDLEKLTHELEK 934
Query: 327 EFLLKE-------ATESRHKYEQMKQQEVQLKQQLSLYMDKFEEFQTTMAKSNELFTTFR 379
L KE +T+ R+K + K E LK+ L + +K + + +S R
Sbjct: 935 IGLNKERLLHDEQSTDDRYKLLESK-LESTLKKSLEIKEEKIAALEARLEESTNYNQQLR 993
Query: 380 QEMEKMTKKIKKLEK----------------ETIIWRTKWENNNKALLQMAEEKTVRDKE 423
QE++ + K + L++ E W + + + LL++ + ++
Sbjct: 994 QELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERN 1053
Query: 424 YKALQIKLERLEKLCRALQTERNELNEKVEVLKEQ 458
LQ + + L+ + L+T+ N L ++ L+ Q
Sbjct: 1054 NATLQAEKQALKTQLKQLETQNNNLQAQILALQRQ 1088
Score = 69.7 bits (169), Expect = 6e-12
Identities = 76/330 (23%), Positives = 152/330 (46%), Gaps = 25/330 (7%)
Query: 154 EKLAALCKKYADLLEESRSVQKQMKILQKK---QAQIVKEKVHLQSEHSKAILARSKLES 210
E + K + + E R ++K+++ ++K ++ E HL+ E+ + L+
Sbjct: 594 ESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKI 653
Query: 211 LCRELQRHNKTLKEENMQQAREEEERRKEATAHFQITLDEIQAQLEQHDIHNAKLRQENI 270
C +++ L++EN + RE + +K + +T QLE + N++L +EN+
Sbjct: 654 TCEKIE----ALEQENSELERENRKLKKTLDSFKNLTF-----QLESLEKENSQLDEENL 704
Query: 271 ELGEKLKKLIEQYALREEHIDKVFKRKELQQQLVDAKLQQTTQLIKEADEKHQREREFLL 330
EL ++ L + +++ + + KEL+ + +L++ +L+K + +K +R
Sbjct: 705 ELRRNVESL-KCASMKMAQLQ--LENKELESE--KEQLKKGLELLKASFKKTERLEVSYQ 759
Query: 331 KEATESRHKYEQMKQQEVQLKQQLSLYMDKFEEFQTTMAKSNELFTTFRQEMEKMTKKIK 390
E++ + ++ ++ QQL + E T+ K+ E + +E++ K+ K
Sbjct: 760 GLDIENQRLQKTLENSNKKI-QQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENK 818
Query: 391 KLEKETIIW---RTKWENNNKALLQMAEEKTVRDKEYKALQIKLERLEKLCRALQTERNE 447
LE+ET + + E NK L Q AE ++D + +K+ LEK + L E
Sbjct: 819 SLEQETSQLEKDKKQLEKENKRLRQQAE---IKDTTLEENNVKIGNLEKENKTLSKEIGI 875
Query: 448 LNEKVEVLKE-QVSIKAAIKAANRDLATPV 476
E LKE + K +K A D+ T V
Sbjct: 876 YKESCVRLKELEKENKELVKRATIDIKTLV 905
Score = 66.6 bits (161), Expect = 5e-11
Identities = 100/433 (23%), Positives = 182/433 (42%), Gaps = 59/433 (13%)
Query: 113 EARTDPPDGQQDSECNRNKEKTLGKEVLLLMQALNTLSTPEEKLAALCKKYADLLEESRS 172
E +T D + + +K L KE L L L+ + + KK +L+EE+ +
Sbjct: 358 ETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDR---KKIEELMEENMT 414
Query: 173 VQKQMKILQKKQAQIVKEKVHLQSE-------------------HSKAILARSKLESLCR 213
L+ Q Q + E +HL E H L S+L L
Sbjct: 415 -------LEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEM 467
Query: 214 ELQRHNKTLKE---------ENMQQAREEEERRKEATAHFQITLDEIQAQLEQHDIHNAK 264
E Q KT++E N + + E+ + + +I +EI E+ + N +
Sbjct: 468 ENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQ--EKQSLQNCQ 525
Query: 265 -LRQENIELGEKLKKLIEQYALREEHIDKVFKRKELQQQLVDAKLQQTTQLIKEADEKH- 322
L ++ ++ +L+K IE E K+ +++ + L+Q +Q+ EA K
Sbjct: 526 NLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDI 585
Query: 323 QREREFLLKEATESRHKYEQMKQQEVQLKQQLSLYMDKFEEFQTT------MAKSNELFT 376
++E + L + E+ K +++ ++ Q+K++L Y +K E + + K NEL
Sbjct: 586 EKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQ 645
Query: 377 TFRQEMEKMTKKIKKLEKETIIWRTKWENNNKALLQMAEEKTVRDKEYKALQIKLERLEK 436
++ +KI+ LE+E ++ E N+ L +KT+ +K L +LE LEK
Sbjct: 646 KKITNLKITCEKIEALEQEN----SELERENRKL-----KKTL--DSFKNLTFQLESLEK 694
Query: 437 LCRALQTERNELNEKVEVLKEQVSIKAAIKAANRDLATPVMQPCTALDSHKELNTSSKRA 496
L E EL VE LK A ++ N++L + Q L+ K ++R
Sbjct: 695 ENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERL 754
Query: 497 LGAHLEAEPKSQR 509
++ + ++QR
Sbjct: 755 EVSYQGLDIENQR 767
Score = 55.1 bits (131), Expect = 2e-07
Identities = 84/366 (22%), Positives = 154/366 (42%), Gaps = 56/366 (15%)
Query: 148 TLSTPEEKLAALCKKYAD-------LLEESRSVQKQMKILQKKQAQ---------IVKEK 191
+L EEK+AAL + + L +E ++V+K + L+++Q + I E
Sbjct: 967 SLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGED 1026
Query: 192 VHLQSEHSKAILARSKLESLCRELQRHNKTLKEEN------MQQAREEEERRKEATAHFQ 245
+ E + K++ E++R+N TL+ E ++Q + + Q
Sbjct: 1027 NKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQ 1086
Query: 246 ITLDEIQAQLEQHDIHNAKLRQENIELG--------EKLKKLIEQYALREEHIDKVFKRK 297
+Q Q NAKL+ EN L + + LI+Q +L E+ + V K +
Sbjct: 1087 RQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENEN-ESVIKER 1145
Query: 298 ELQQQLVDAKLQQTTQLIKEADEKHQREREFLLKE--ATESRHKYEQMKQQEVQ------ 349
E + L D+ ++ +L + E+ E E L+ + +S HK +++ ++++
Sbjct: 1146 EDLKSLYDSLIKDHEKL-ELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQL 1204
Query: 350 LKQ--QLSLYMDKFEEFQTTMAKSNELFTTFRQEMEKMTKKIKKLE-------KETIIWR 400
LKQ QL + Q M N+ T E +K+ + +L KET + +
Sbjct: 1205 LKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKETEVLQ 1264
Query: 401 TKWEN-----NNKALLQ--MAEEKTVRDKEYKALQIKLERLEKLCRALQTERNELNEKVE 453
T +N NN L Q + E + ++Y+ L I +L C L + L E+
Sbjct: 1265 TDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENR 1324
Query: 454 VLKEQV 459
L +Q+
Sbjct: 1325 HLLDQI 1330
Score = 45.4 bits (106), Expect = 1e-04
Identities = 80/376 (21%), Positives = 147/376 (39%), Gaps = 89/376 (23%)
Query: 167 LEESRSVQKQMKILQKKQAQIVKEKVHLQSEHSKAIL--------------ARSKLESLC 212
+E + Q+ ++ L K A +K + + EHS+ I+ A S +S C
Sbjct: 176 MEVTDMSQEDIEPLLKNMALHLKRLIDERDEHSETIIELSEERDGLHFLPHASSSAQSPC 235
Query: 213 -------RELQRHNKTLKEENMQQAREEEERRKEATAHFQITLDEIQAQLEQHDIHNAKL 265
E ++H + + R + +E T L + + +LEQ +I +L
Sbjct: 236 GSPGMKRTESRQHLSVELADAKAKIRRLRQELEEKTEQ----LLDCKQELEQMEIELKRL 291
Query: 266 RQENIEL-----------------------GEKLKKLIEQYALREEHID----KVFKRKE 298
+QEN+ L +KL+ + +Y R I+ +V + KE
Sbjct: 292 QQENMNLLSDARSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKE 351
Query: 299 LQQQLVDAKLQQTTQL---IKEADEKHQREREFL-LK--------EATESRHKYEQMKQQ 346
Q L++ K QL +D+ H+ E+E L LK E R K E++ ++
Sbjct: 352 DNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEE 411
Query: 347 EVQLKQQLSLYMD-------KFEEFQTTMAKS-----------NELFTTFRQEMEKMTKK 388
+ L+ MD + E+ T S NEL ++ ++E +
Sbjct: 412 NMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQS 471
Query: 389 IKKLEKETIIWRTKWENNNKALLQMAEEKTVRDKEYKALQIK-------LERLEKLCRAL 441
+ K +E E N +L+M +E K+ + L+ + L+ + L + L
Sbjct: 472 LTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDL 531
Query: 442 QTERNELNEKVEVLKE 457
E+ +L + +E L+E
Sbjct: 532 MKEKAQLEKTIETLRE 547
Score = 44.3 bits (103), Expect = 3e-04
Identities = 60/294 (20%), Positives = 123/294 (41%), Gaps = 41/294 (13%)
Query: 135 LGKEVLLLMQALNTLSTPEEKL----AALCKKYADLLEESRSVQKQMKILQKKQAQIVKE 190
L ++ + L + TL T KL + L + L+ ++ + Q L+ + ++KE
Sbjct: 1085 LQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKE 1144
Query: 191 KVHLQS-------EHSKAILARSKLESLCRELQRHNKTLK-------------EENMQQA 230
+ L+S +H K L + S L + TLK E+ Q
Sbjct: 1145 REDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQL 1204
Query: 231 REEEERRKEATAHFQITLDEIQAQLEQHDIHNA---KLRQENIELGEKLKKLI-EQYALR 286
+++ + ++ ++ +++ + + H+ A KL EN L +L+ E L+
Sbjct: 1205 LKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKETEVLQ 1264
Query: 287 EEH--IDKVFKRKELQQQLVDA---KLQQTTQLIKEADEKHQREREFL------LKEATE 335
+H + + +L+Q ++A KL++ Q + K + E L L+E E
Sbjct: 1265 TDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEE--E 1322
Query: 336 SRHKYEQMKQQEVQLKQQLSLYMDKFEEFQTTMAKSNELFTTFRQEMEKMTKKI 389
+RH +Q++ +Q + L M+ + F + + R++ EK+ +KI
Sbjct: 1323 NRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNELRRQKEKLEEKI 1376
Score = 37.4 bits (85), Expect = 0.034
Identities = 41/198 (20%), Positives = 86/198 (43%), Gaps = 24/198 (12%)
Query: 285 LREEHIDKVFKRKELQ-QQLVDAKLQQTTQLIKEADEKHQREREFLLKEATESRHKYEQM 343
+ +E I+ + K L ++L+D + + + +I+ ++E+ FL ++ ++
Sbjct: 181 MSQEDIEPLLKNMALHLKRLIDERDEHSETIIELSEERDGLH--FLPHASSSAQSPCGSP 238
Query: 344 KQQEVQLKQQLSLYMD----KFEEFQTTMAKSNELFTTFRQEMEKMTKKIKKLEKETIIW 399
+ + +Q LS+ + K + + + E +QE+E+M ++K+L++E
Sbjct: 239 GMKRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQE---- 294
Query: 400 RTKWENNNKALLQMAEEKTVRDKEYKALQIKLERLEKLCRALQTERNELNE------KVE 453
N LL A + E AL+ K R++KL + + L++ +VE
Sbjct: 295 -------NMNLLSDARSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVE 347
Query: 454 VLKEQVSIKAAIKAANRD 471
LKE + K D
Sbjct: 348 ELKEDNQVLLETKTMLED 365
>gi|31982906 cingulin-like 1 [Homo sapiens]
Length = 1302
Score = 75.9 bits (185), Expect = 9e-14
Identities = 88/417 (21%), Positives = 190/417 (45%), Gaps = 33/417 (7%)
Query: 106 REEIPGGEARTDPPDGQQDSECNRNKEKTLGKEVLLLMQALNTLSTPEEKLAALCKKYAD 165
+EE+ + D Q D+E +E +E ++ L + S E+ A +
Sbjct: 768 KEEVSSHDQEMDKLKEQYDAELQALRESV--EEATKNVEVLASRSNTSEQDQAGTEMRVK 825
Query: 166 LL-EESRSVQKQMKILQKKQAQIVKEKVHLQSEHSKAILARSKLESLCRELQRHNKTLKE 224
LL EE+ +Q + + L+++ AQ+ ++ L+ + +KA K E R+L E
Sbjct: 826 LLQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQL--------E 877
Query: 225 ENMQQAREEEERRKEATAHFQITLDEIQAQLEQHDIHNAKLRQ---ENIELGEKLKKLIE 281
E + AR+EE+ A + L+ Q L Q +L + E E E+L++L
Sbjct: 878 EALVHARKEEKEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKN 937
Query: 282 QYALREEHIDKVFKRKELQQ-QLVDAKLQQTTQLIKEADE---KHQREREFLLKEATESR 337
+ H+ K ++ + + +V+A T +L + DE K++RE + ++ E
Sbjct: 938 EMENERWHLGKTIEKLQKEMADIVEASRTSTLELQNQLDEYKEKNRRELAEMQRQLKEKT 997
Query: 338 HKYEQMKQQEVQLKQQLSLYMDKFEEFQTTMAKSNELFTTFRQEMEKMTKKIK-KLEKET 396
+ E+ + ++++ ++ L ++ ++Q ++ + T RQ +E+ K ++ +LE ++
Sbjct: 998 LEAEKSRLTAMKMQDEMRLMEEELRDYQ----RAQDEALTKRQLLEQTLKDLEYELEAKS 1053
Query: 397 IIWRTKWENNNKALLQMAEEKTVR-----DKEYKALQIKLERLEKLCRALQTERNELNEK 451
+ +++ L++ E+K + ++E + ER+ + ++ RNEL ++
Sbjct: 1054 HL-----KDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERISRSREQMEQLRNELLQE 1108
Query: 452 VEVLKEQVSIKAAIKAANRDLATPVMQPCTALDSHKELNTSSKRALGAHLEAEPKSQ 508
++ K +++ N+DL + ++ + S KE A A LE +S+
Sbjct: 1109 RAARQDLECDKISLERQNKDLKSRIIHLEGSYRSSKEGLVVQMEARIAELEDRLESE 1165
Score = 67.8 bits (164), Expect = 2e-11
Identities = 85/385 (22%), Positives = 169/385 (43%), Gaps = 72/385 (18%)
Query: 165 DLLEESRSVQKQMKILQKKQAQIVKEKVHLQSEHSKAILARSKLESLCRELQRHNKTLKE 224
DLLE+ + ++ LQ++ VK + +++ E + +L S E N TL++
Sbjct: 611 DLLEQKSKLTIEVAELQRQLQLEVKNQQNIKEERERMRANLEELRSQHNEKVEENSTLQQ 670
Query: 225 ENMQQAREEEERRKEATAHFQITLD---------EIQAQL-EQHDIHNAKLRQENIELGE 274
+ E E RK FQ+ ++ ++Q QL E HD ++ R E+ E G
Sbjct: 671 ---RLEESEGELRKNLEELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAKRSEDREKG- 726
Query: 275 KLKKLIEQYALREEHIDKVFKRKELQQQLVDAKLQQTTQL---IKEADEKHQREREFL-- 329
LIE+ ++ + + KE Q+ L+ + ++ T L +KE H +E + L
Sbjct: 727 ---ALIEELLQAKQDLQDLLIAKEEQEDLLRKRERELTALKGALKEEVSSHDQEMDKLKE 783
Query: 330 ------------LKEATES-------------------------RHKYEQMKQQEVQLKQ 352
++EAT++ + + E+++ + +L++
Sbjct: 784 QYDAELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEELER 843
Query: 353 QLSLYMDKFEEFQTTMAKSNELFTTFRQEMEKMTKKI---KKLEKETIIWRTKWENNNKA 409
+++ + E+ + AK+ E + E+ ++ + + +K EKE + R EN +A
Sbjct: 844 RVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALENELEA 903
Query: 410 ----LLQMAEEKTVRDKEYKALQIKLERLEKLCRALQTERNELNEKVEVLKEQVSIKAAI 465
L Q +E+ ++ K + E+L +L ++ ER L + +E L++++ A I
Sbjct: 904 AQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKNEMENERWHLGKTIEKLQKEM---ADI 960
Query: 466 KAANRDLATPVMQPCTALDSHKELN 490
A+R T ++ LD +KE N
Sbjct: 961 VEASR---TSTLELQNQLDEYKEKN 982
Score = 60.5 bits (145), Expect = 4e-09
Identities = 95/436 (21%), Positives = 190/436 (43%), Gaps = 62/436 (14%)
Query: 58 SQSNDILQHQGSNCGGTSNKHSLEEDEGSDFITENRNLVSPAYCTQESREEIPGGEARTD 117
S+SN Q Q GT + L ++E + L Q E++ G EA+
Sbjct: 808 SRSNTSEQDQA----GTEMRVKLLQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAK 863
Query: 118 PPDGQQDSECNRNKEKTLG-----KEVLLLMQAL-NTLSTPEEKLAALCKKYADLLEESR 171
+ + E + +E + KE + +AL N L + L+ ++ L E+ +
Sbjct: 864 ETLKKYEGEIRQLEEALVHARKEEKEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLK 923
Query: 172 SVQKQMKILQKKQAQIVKEKVHLQSEHSKAILARSKLESLCRELQRHNKTLKEENMQQAR 231
+Q + L++ + ++ E+ HL K I KL+ ++ ++T E Q
Sbjct: 924 EESEQKEQLRRLKNEMENERWHL----GKTI---EKLQKEMADIVEASRTSTLELQNQLD 976
Query: 232 EEEERRKEATAHFQITLDEIQAQLEQHDIHNAKLRQENIELGEKLKKLIEQYALREEHID 291
E +E+ + A E+Q QL++ + K R +++ ++++ + E+ + D
Sbjct: 977 EYKEKNRRELA-------EMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQD 1029
Query: 292 KVF-KRKELQQQLVDAKLQ---------QTTQLIKEADEK---------HQREREFLLKE 332
+ KR+ L+Q L D + + ++L+K+ ++K +R LL E
Sbjct: 1030 EALTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSE 1089
Query: 333 -ATESRHKYEQMKQQEVQLK-QQLSLYMDKFE-EFQTTMAKSN--ELFTTFRQEME---- 383
+ SR + EQ++ + +Q + + L DK E Q KS L ++R E
Sbjct: 1090 RISRSREQMEQLRNELLQERAARQDLECDKISLERQNKDLKSRIIHLEGSYRSSKEGLVV 1149
Query: 384 KMTKKIKKLEKETIIWRTKWENNNKALLQMAEEKTVRDKEYKALQIKLERLEKLCRALQT 443
+M +I +LE R + E ++A LQ++ + R + +Q+ E L +L
Sbjct: 1150 QMEARIAELED-----RLESEERDRANLQLSNRRLERKVKELVMQVDDEHL-----SLTD 1199
Query: 444 ERNELNEKVEVLKEQV 459
++++L+ +++ +K QV
Sbjct: 1200 QKDQLSLRLKAMKRQV 1215
Score = 50.1 bits (118), Expect = 5e-06
Identities = 52/229 (22%), Positives = 103/229 (44%), Gaps = 12/229 (5%)
Query: 132 EKTLGKEVLLLMQALNTLSTPEEKLAALCKKYADLLE-ESRSVQKQMKILQKKQAQIVKE 190
E+TL K++ ++A + L +L + LE E + +L ++ ++ ++
Sbjct: 1039 EQTL-KDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERISRSREQ 1097
Query: 191 KVHLQSEHSKAILARSKLESLCRELQRHNKTLKEENMQQAREEEERRKEATAHFQITLDE 250
L++E + AR LE L+R NK LK + ++ + + E
Sbjct: 1098 MEQLRNELLQERAARQDLECDKISLERQNKDLKSRIIHLEGSYRSSKEGLVVQMEARIAE 1157
Query: 251 IQAQLEQHDIHNAKLRQENIELGEKLKKLIEQYALREEHIDKVFKRKELQQQLVDAKLQQ 310
++ +LE + A L+ N L K+K+L+ Q + +EH+ ++ +L +L K Q
Sbjct: 1158 LEDRLESEERDRANLQLSNRRLERKVKELVMQ--VDDEHLSLTDQKDQLSLRLKAMKRQ- 1214
Query: 311 TTQLIKEADEKHQR---EREFLLKEATESRHKYEQMKQQEVQLKQQLSL 356
++EA+E+ R ++ L +E E E ++ Q +K+ L L
Sbjct: 1215 ----VEEAEEEIDRLESSKKKLQRELEEQMDMNEHLQGQLNSMKKDLRL 1259
Score = 29.3 bits (64), Expect = 9.3
Identities = 42/196 (21%), Positives = 77/196 (39%), Gaps = 8/196 (4%)
Query: 309 QQTTQLIKEADEKHQREREFLLKEATESRHKYEQMKQQEVQLKQQLSLYMDKFEEFQTTM 368
Q T L+K E Q+ E K+ + K E + K++++L +K + ++
Sbjct: 534 QATPDLLKGQQELTQQTNEETAKQILYNYLK-EGSTDNDDATKRKVNLVFEKIQTLKSRA 592
Query: 369 AKS---NELFTTFRQEMEKMTKKIKKLEKETIIWRTKWENNNKALLQMAEEKTVRDKEYK 425
A S N E++ + ++ KL E + + + K + EE+ +
Sbjct: 593 AGSAQGNNQACNSTSEVKDLLEQKSKLTIEVAELQRQLQLEVKNQQNIKEERERMRANLE 652
Query: 426 ALQI----KLERLEKLCRALQTERNELNEKVEVLKEQVSIKAAIKAANRDLATPVMQPCT 481
L+ K+E L + L+ EL + +E L + + + RDL + +
Sbjct: 653 ELRSQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMEREQHQTEIRDLQDQLSEMHD 712
Query: 482 ALDSHKELNTSSKRAL 497
LDS K K AL
Sbjct: 713 ELDSAKRSEDREKGAL 728
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 75.1 bits (183), Expect = 1e-13
Identities = 90/408 (22%), Positives = 191/408 (46%), Gaps = 46/408 (11%)
Query: 76 NKHSLEEDEGSDFITENRNLVSPAYCTQESREEIPGGEARTDPPDGQQDSECNRNKEKTL 135
++H++++ EG E R+L+S + + + E+ E Q+ +E T
Sbjct: 149 SQHAVKQLEG-----EARDLISRLHDSWKFAGEL---EQALSAVATQKKKADRYIEELTK 200
Query: 136 GKEVLLLMQALNTLSTPE--EKLAALCKKYADLLEESRSVQKQMKILQKK---------Q 184
++ L L NT++ E EK A L +K + E +Q +K L++K Q
Sbjct: 201 ERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQ 260
Query: 185 AQIVKEKVHLQSEHSKAILARSKLESLCRELQRHNKTLKEENMQQAREEEERRKEATAHF 244
Q+ E HL E +KL++ E + N+ L ++ ++ +EE+ +E
Sbjct: 261 QQLQAEADHLGKELQSV---SAKLQAQVEENELWNR-LNQQQEEKMWRQEEKIQEWEEKI 316
Query: 245 QITLDEIQAQLEQHDIHNAKLRQENIELGEKLKKLIEQYALREEHIDKVFKRKELQQQL- 303
Q ++I+ Q E+ K+R++ + EK +K+ Q + E +K+ + +E+ +
Sbjct: 317 QEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKE 376
Query: 304 -----VDAKLQQTTQLIKEADEKHQREREFLLKEATESRHKYEQMKQQEVQLKQQLSLYM 358
++ K+ + + I+E +EK Q E + ++E + + + +M +QE ++++Q
Sbjct: 377 EKIRELEEKMHEQEK-IREQEEKRQEEEK--IREQEKRQEQEAKMWRQEEKIREQ----E 429
Query: 359 DKFEEFQTTMAKSNELF--------TTFRQEMEKMTKKIKKLEKETIIWRTKWENNNKAL 410
+K E + M + E RQE E+M ++ +K+ ++ IWR K + + +
Sbjct: 430 EKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEK 489
Query: 411 LQMAEEKTVRDKEYKALQIKLERLEKLCRALQTERNELNEKVEVLKEQ 458
++ EEK R +E + + E++ + + + ++ E+ E ++EQ
Sbjct: 490 IRKQEEKVWRQEE--KMHDQEEKIREQEEKMWRQEEKIREQEEKIREQ 535
Score = 70.1 bits (170), Expect = 5e-12
Identities = 75/314 (23%), Positives = 155/314 (49%), Gaps = 22/314 (7%)
Query: 162 KYADLLEESRS-VQKQMKILQKKQAQIVKEKVHLQSEHSKAILARSKLESLCRELQRHNK 220
K+A LE++ S V Q K + ++ KE+ L E + + +L+ +LQ +
Sbjct: 172 KFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQ 231
Query: 221 TLKEENMQ-QAREEEERRKEATAHFQITLDEIQAQLE----QHDIHNAKLRQ--ENIELG 273
++ E + Q +E +RK A + ++QA+ + + +AKL+ E EL
Sbjct: 232 LVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELW 291
Query: 274 EKLKKLIEQYALREEHIDKVFKRKELQQQLVDAKLQQTTQLIKEADEKHQREREFLLKEA 333
+L + E+ R+E + ++ K +Q+Q + K+++ + I+E +EK +R+ E + ++
Sbjct: 292 NRLNQQQEEKMWRQEEKIQEWEEK-IQEQ--EEKIREQEEKIREQEEKMRRQEEMMWEKE 348
Query: 334 TESRHKYEQMKQQEVQLKQQLSLYMDKFEEFQTTMAKSNEL-----FTTFRQEMEKMTKK 388
+ R + E M ++E ++++ + +K E+ + K +E RQE EK+ ++
Sbjct: 349 EKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQ 408
Query: 389 IKKLEKETIIWRTKWE-NNNKALLQMAEEKTVRDKEYKALQIKLERLEKLCRALQTERNE 447
K+ E+E +WR + + + ++ E+K R +E Q K+ EK + E+ E
Sbjct: 409 EKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEK-----RQEQEE 463
Query: 448 LNEKVEVLKEQVSI 461
+ + E ++EQ I
Sbjct: 464 MWRQEEKIREQEEI 477
Score = 67.0 bits (162), Expect = 4e-11
Identities = 74/366 (20%), Positives = 175/366 (47%), Gaps = 17/366 (4%)
Query: 103 QESREEIPGGEARTDPPDGQQDSECNRNKEKTLGKEVLLLMQALNTLSTPEEKLAALCKK 162
QE E+I E + +Q+ + R +E KE + Q + EEK+ L +
Sbjct: 317 QEQEEKIREQEEKIR----EQEEKMRRQEEMMWEKEEKMRRQE-EMMWEKEEKMRRLEEM 371
Query: 163 YADLLEESRSVQKQMKILQKKQAQIVKEKVHLQSEHSKAILARSKLESLCRELQRHNKTL 222
+ E+ R ++++M +K ++E+ + E K + E + ++ K
Sbjct: 372 MWEKEEKIRELEEKMHEQEK-----IREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIR 426
Query: 223 KEENMQQAREEEERRKEATAHFQITLDEIQAQLEQHDI--HNAKLRQENIELGEKLKKLI 280
++E + +E++ R+E H Q + E + + EQ ++ K+R++ E+ + +K+
Sbjct: 427 EQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQE-EIWRQKEKMH 485
Query: 281 EQYALREEHIDKVFKRKELQQQLVDAKLQQTTQLIKEADEKHQREREFLLKEATESRHKY 340
EQ +R++ +KV++++E + +Q ++ ++ E+ RE+E ++E E +
Sbjct: 486 EQEKIRKQE-EKVWRQEEKMHDQEEKIREQEEKMWRQ--EEKIREQEEKIREQEEKIREQ 542
Query: 341 EQMKQQEVQLKQQLSLYMDKFEEFQTTMAKSNELFTTFRQEMEKMTKKIKKLEKETIIWR 400
E+M Q++ + + M + E+ + K E R++ EK+ ++ +K+ ++ R
Sbjct: 543 EEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIR 602
Query: 401 TKWENNNKALLQMAEEKTVRDKEYKALQIKLERLEKLCRALQTERNELNEKVEVLKE-QV 459
+ E + +M E++ ++ + +Q + E++ + + + L ++ E ++E Q
Sbjct: 603 EQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQE 662
Query: 460 SIKAAI 465
++AAI
Sbjct: 663 HLEAAI 668
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 74.7 bits (182), Expect = 2e-13
Identities = 96/454 (21%), Positives = 193/454 (42%), Gaps = 29/454 (6%)
Query: 60 SNDILQHQGSNCGGTSNKHSLEEDEGSDFIT--ENRNLVSPAYCTQESREEIPGGEARTD 117
S + ++ + C + E D + E N ++ A ++ + E +T
Sbjct: 1401 SEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTK 1460
Query: 118 PPDGQQDSECNRNKEKTLGKEVLLLM----QALNTLSTPEEKLAALCKKYADLLEESRSV 173
+ Q + E + + ++L E+ L +AL+ L T + + L ++ ADL E+
Sbjct: 1461 CEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAEN 1520
Query: 174 QKQMKILQKKQAQIVKEKVHLQSEHSKAILARSKLESLCRELQRHNKTLKEENMQQAREE 233
K + L+K + QI EK +Q +A A E+ +Q +K E ++ E+
Sbjct: 1521 GKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAEK 1580
Query: 234 EERRKEATAHFQITLDEIQAQLEQHDIHNAKLRQENIELGEKLKKLIEQYALREEHIDK- 292
+E ++ ++Q T++ +Q+ L+ + R E I L +K++ + + ++ H ++
Sbjct: 1581 DEEIEQLKRNYQRTVETMQSALDA----EVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQ 1636
Query: 293 ----VFKRKELQQQLVDAKLQQTTQLIKEADEKHQ-----REREFLLKEATESRHKYEQM 343
+ + +Q QL D +L L + D K Q R L E E R EQ
Sbjct: 1637 AAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQT 1696
Query: 344 KQQEVQLKQQLSLYMDKFEEFQTTMAKSNELFTTFRQEMEKMTKKIKKLEKETIIWRTKW 403
++ +Q+L +D E Q ++ L T ++ + + ++E + R
Sbjct: 1697 ERARKLAEQEL---LDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAE 1753
Query: 404 ENNNKALLQMAEEKTVRDKEYKALQIKLERLEKLCRALQTERNELNEKVEVLKEQVSIKA 463
E KA+ A + +E K Q LE++ + L+ +L +++ EQ+++K
Sbjct: 1754 EKAKKAITDAA----MMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDE-AEQLALKG 1808
Query: 464 AIKAANRDLATPVMQPCTALDSHKELNTSSKRAL 497
K + L T + + L+ ++ NT S + L
Sbjct: 1809 GKKQIQK-LETRIRELEFELEGEQKKNTESVKGL 1841
Score = 64.7 bits (156), Expect = 2e-10
Identities = 82/383 (21%), Positives = 167/383 (43%), Gaps = 51/383 (13%)
Query: 115 RTDPPDGQQDSECNRNKEKTLGKEVLLLMQALNTLSTPEEKL-AALCKKYAD----LLEE 169
R + G ++ NK++ E L L + L + E + AAL KK+AD L E+
Sbjct: 1150 RLEEAGGVTSTQIELNKKREA--EFLKLRRDLEEATLQHEAMVAALRKKHADSVAELGEQ 1207
Query: 170 SRSVQKQMKILQKKQAQIVKEKVHLQSEHSKAILARSKLESLCREL--QRHNKTLKEENM 227
++Q+ + L+K++++ E L S +++ LE +CR L Q K E +
Sbjct: 1208 IDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEI 1267
Query: 228 QQAREEEERRKEATAHFQITLDEIQAQLEQHDIHNAKL---RQENIELGEKLKKLIEQY- 283
Q++ E +K + Q E+ QLE+ + ++L +Q + E+LK+ +E+
Sbjct: 1268 QRSLSELTTQK---SRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEEN 1324
Query: 284 ------------------ALREEHIDKVFKRKELQQQLVDA-------KLQQTTQLIKEA 318
LRE++ ++ + ELQ+ L A + + T I+
Sbjct: 1325 KAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRT 1384
Query: 319 DEKHQREREFLLKEATESRHKYEQMKQQEVQLKQQLSLYMDKFEEFQTTMAKSNELFTTF 378
+E + +++ L + +S + E + + L++ + E+ + ++N L
Sbjct: 1385 EELEEAKKK-LAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAA- 1442
Query: 379 RQEMEKMTKKIKKLEKETIIWRTKWENNNKAL-LQMAEEKTVRDKEYKALQIKLERLEKL 437
+ KK + +K W+TK E + L + E +++ + +K E L++L
Sbjct: 1443 ------LDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQL 1496
Query: 438 CRALQTERNELNEKVEVLKEQVS 460
++ E L +++ L EQ++
Sbjct: 1497 -ETVKRENKNLEQEIADLTEQIA 1518
Score = 62.4 bits (150), Expect = 1e-09
Identities = 76/391 (19%), Positives = 169/391 (43%), Gaps = 21/391 (5%)
Query: 116 TDPPDGQQDSECNRNKEKTLGKEVLLLMQALNTLSTPEEKLAALCKKYADLLEESRSVQK 175
T+ G ++ +EK +E QAL+ L E+K+ +L K + L ++ ++
Sbjct: 980 TEELSGLDETIAKLTREKKALQEAH--QQALDDLQAEEDKVNSLNKTKSKLEQQVEDLES 1037
Query: 176 QMKILQKKQAQIVKEKVHLQSEHSKAILARSKLESLCRELQRHNKTLKEENMQ----QAR 231
++ +K + + + K L+ + LA+ + L + Q+ ++ LK+++ + Q++
Sbjct: 1038 SLEQEKKLRVDLERNKRKLEGDLK---LAQESILDLENDKQQLDERLKKKDFEYCQLQSK 1094
Query: 232 EEEERR-----KEATAHFQITLDEIQAQLEQHDIHNAKLRQENIELGEKLKKLIEQYALR 286
E+E+ ++ Q ++E++ ++E AK ++ + +L++L E+
Sbjct: 1095 VEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERL--- 1151
Query: 287 EEHIDKVFKRKELQQQLVDAKLQQTTQLIKEADEKHQREREFLLKEATESRHKYEQMKQQ 346
EE + EL ++ +A+ + + ++EA +H+ L K+ +S + +
Sbjct: 1152 EEAGGVTSTQIELNKKR-EAEFLKLRRDLEEATLQHEAMVAALRKKHADSVAELGEQIDN 1210
Query: 347 EVQLKQQLSLYMDKFEEFQTTMAKSNELFTTFRQEMEKMTKKIKKLEKETIIWRTKWENN 406
++KQ+L +F+ ++ S E + + +EK+ + ++ E R K E
Sbjct: 1211 LQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEA---RGKNEEI 1267
Query: 407 NKALLQMAEEKTVRDKEYKALQIKLERLEKLCRALQTERNELNEKVEVLKEQVSIKAAIK 466
++L ++ +K+ E L +LE E + L + ++ E LK Q+ + K
Sbjct: 1268 QRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAK 1327
Query: 467 AANRDLATPVMQPCTALDSHKELNTSSKRAL 497
A C L E K L
Sbjct: 1328 NALAHALQSSRHDCDLLREQYEEEQEGKAEL 1358
Score = 62.0 bits (149), Expect = 1e-09
Identities = 74/311 (23%), Positives = 143/311 (45%), Gaps = 47/311 (15%)
Query: 183 KQAQIVKEKVHLQSEHSKAILARSKLESLCRELQRHNKTL-------------KEENMQQ 229
K A+ KE ++ E K +K E+ +EL+ TL + EN+
Sbjct: 842 KSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLD 901
Query: 230 AREEEERRKEATAHFQITLDEIQAQLEQHDIHNAKLRQENIELGE---KLKKLIEQYALR 286
A E ++ +A + + E+ + E + NA+L + +L + +LKK I+ L
Sbjct: 902 AEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELT 961
Query: 287 EEHIDK-----VFKRKELQQQL--VDAKLQQTTQLIKEADEKHQREREFLLKEATESRHK 339
++K K K L ++L +D + + T+ K E HQ+ + L E K
Sbjct: 962 LAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAE----EDK 1017
Query: 340 YEQMKQQEVQLKQQLSLYMDKFEEFQTTMAKSNELFTTFRQEMEKMTKKIK---KLEKET 396
+ + + +L+QQ+ E+ ++++ + +L R ++E+ +K++ KL +E+
Sbjct: 1018 VNSLNKTKSKLEQQV-------EDLESSLEQEKKL----RVDLERNKRKLEGDLKLAQES 1066
Query: 397 IIWRTKWENNNKALLQMAEEKTVRDKEYKALQIKLERLEKLCRALQTERNELNEKVEVLK 456
I+ EN+ + Q+ E +D EY LQ K+E + L Q + EL ++E L+
Sbjct: 1067 IL---DLENDKQ---QLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELE 1120
Query: 457 EQVSIKAAIKA 467
E++ + A +A
Sbjct: 1121 EEIEAERATRA 1131
Score = 44.7 bits (104), Expect = 2e-04
Identities = 54/289 (18%), Positives = 130/289 (44%), Gaps = 41/289 (14%)
Query: 132 EKTLGKEVLLLMQALNTLSTPEEKLAALCKKYADLLEESRSVQKQMKILQKKQAQIVKEK 191
++ L +++ ++ + N L E+L A ++ E +R + +Q + ++ Q+
Sbjct: 1665 QEDLKEQLAIVERRANLLQAEVEELRATLEQ----TERARKLAEQELLDSNERVQL---- 1716
Query: 192 VHLQSEHSKAILARSKLESLCRELQRHNKTLKEENMQQAREEEERRKEATAHFQITLDEI 251
L ++++ I + KLE+ +LQ E+ + AR EE+ K+A + +E+
Sbjct: 1717 --LHTQNTSLIHTKKKLETDLMQLQSE----VEDASRDARNAEEKAKKAITDAAMMAEEL 1770
Query: 252 QAQLEQHDIHNAKLRQENIELGEKLKKL------IEQYALR--EEHIDKVFKR-KELQQQ 302
+ + + +A L + L + +K L EQ AL+ ++ I K+ R +EL+ +
Sbjct: 1771 KKEQDT----SAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFE 1826
Query: 303 LVDAKLQQTTQLIKEADEKHQREREFLLKEATESRH-------------KYEQMKQQEVQ 349
L + + ++ T+ +K + +R +E + + ++ K + K+Q +
Sbjct: 1827 L-EGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEE 1885
Query: 350 LKQQLSLYMDKFEEFQTTMAKSNELFTTFRQEMEKMTKKIKKLEKETII 398
+Q + ++ KF + Q + ++ E ++ K+ K + ++
Sbjct: 1886 ADEQANAHLTKFRKAQHELEEAEERADIAESQVNKLRAKTRDFTSSRMV 1934
Score = 40.4 bits (93), Expect = 0.004
Identities = 48/203 (23%), Positives = 90/203 (44%), Gaps = 14/203 (6%)
Query: 260 IHNAKLRQENIELGEKLKKLIEQYALREEHIDKVFKRKELQQQLVDAKLQQTTQLIKEAD 319
+ +A+ +E + E+ +K ++ A E KRKEL+++LV +Q+ L +
Sbjct: 841 LKSAETEKEMATMKEEFQKTKDELAKSEA------KRKELEEKLVTL-VQEKNDLQLQV- 892
Query: 320 EKHQREREFLLKEATESRHKYEQMKQQEVQLKQQLSLYMDKFEEFQTTMAKSNEL---FT 376
Q E E LL + Q E ++K+ D+ E AK +L +
Sbjct: 893 ---QAESENLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECS 949
Query: 377 TFRQEMEKMTKKIKKLEKETIIWRTKWENNNKALLQMAEEKTVRDKEYKALQIKLERLEK 436
+++++ + + K+EKE K +N + L + E +E KALQ ++
Sbjct: 950 ELKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALD 1009
Query: 437 LCRALQTERNELNEKVEVLKEQV 459
+A + + N LN+ L++QV
Sbjct: 1010 DLQAEEDKVNSLNKTKSKLEQQV 1032
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 74.7 bits (182), Expect = 2e-13
Identities = 98/456 (21%), Positives = 191/456 (41%), Gaps = 61/456 (13%)
Query: 59 QSNDILQHQGSNCGGTSNKHSLEEDEGSDFITENRNLVSPAYCTQESREEIPGGEARTDP 118
+ N++LQ + +N T K E E S+ ENR L + ++ E
Sbjct: 639 KENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQ 698
Query: 119 PDGQQDSECNRNKE----------------KTLGKEVLLLMQALNTLSTPEEKLAALCKK 162
D +++ E RN E K L E L + L L +K L
Sbjct: 699 LD-EENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVS 757
Query: 163 YADLLEESRSVQKQMKILQKKQAQIVKEKVHLQSEHS--KAILARSKLES-LCRELQRHN 219
Y L E++ +QK ++ KK Q+ E L+ E+ + L K+ S +L++ N
Sbjct: 758 YQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKEN 817
Query: 220 KTLKEENMQQAREEEERRKEATAHFQITLDEIQAQLEQHDIHNAKLRQENIELGEKLKKL 279
K+L++E Q +++++ KE + + LE++++ L +EN L +++ +
Sbjct: 818 KSLEQETSQLEKDKKQLEKE-NKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEI-GI 875
Query: 280 IEQYALREEHIDKVFKR------------KELQQQLVDAKLQQTTQLIKEADE-KHQRER 326
++ +R + ++K K L++ LV KL +T Q+ + ++ H+ E+
Sbjct: 876 YKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKL-KTQQMNNDLEKLTHELEK 934
Query: 327 EFLLKE--------ATESRHKYEQMKQQEVQLKQQLSLYMDKFEEFQTTMAKSNELFTTF 378
L KE +SR+K + K E LK+ L + +K + + +S
Sbjct: 935 IGLNKERLLHDEQSTDDSRYKLLESK-LESTLKKSLEIKEEKIAALEARLEESTNYNQQL 993
Query: 379 RQEMEKMTKKIKKLEK----------------ETIIWRTKWENNNKALLQMAEEKTVRDK 422
RQE++ + K + L++ E W + + + LL++ + ++
Sbjct: 994 RQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVER 1053
Query: 423 EYKALQIKLERLEKLCRALQTERNELNEKVEVLKEQ 458
LQ + + L+ + L+T+ N L ++ L+ Q
Sbjct: 1054 NNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQ 1089
Score = 69.7 bits (169), Expect = 6e-12
Identities = 76/330 (23%), Positives = 152/330 (46%), Gaps = 25/330 (7%)
Query: 154 EKLAALCKKYADLLEESRSVQKQMKILQKK---QAQIVKEKVHLQSEHSKAILARSKLES 210
E + K + + E R ++K+++ ++K ++ E HL+ E+ + L+
Sbjct: 594 ESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKI 653
Query: 211 LCRELQRHNKTLKEENMQQAREEEERRKEATAHFQITLDEIQAQLEQHDIHNAKLRQENI 270
C +++ L++EN + RE + +K + +T QLE + N++L +EN+
Sbjct: 654 TCEKIE----ALEQENSELERENRKLKKTLDSFKNLTF-----QLESLEKENSQLDEENL 704
Query: 271 ELGEKLKKLIEQYALREEHIDKVFKRKELQQQLVDAKLQQTTQLIKEADEKHQREREFLL 330
EL ++ L + +++ + + KEL+ + +L++ +L+K + +K +R
Sbjct: 705 ELRRNVESL-KCASMKMAQLQ--LENKELESE--KEQLKKGLELLKASFKKTERLEVSYQ 759
Query: 331 KEATESRHKYEQMKQQEVQLKQQLSLYMDKFEEFQTTMAKSNELFTTFRQEMEKMTKKIK 390
E++ + ++ ++ QQL + E T+ K+ E + +E++ K+ K
Sbjct: 760 GLDIENQRLQKTLENSNKKI-QQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENK 818
Query: 391 KLEKETIIW---RTKWENNNKALLQMAEEKTVRDKEYKALQIKLERLEKLCRALQTERNE 447
LE+ET + + E NK L Q AE ++D + +K+ LEK + L E
Sbjct: 819 SLEQETSQLEKDKKQLEKENKRLRQQAE---IKDTTLEENNVKIGNLEKENKTLSKEIGI 875
Query: 448 LNEKVEVLKE-QVSIKAAIKAANRDLATPV 476
E LKE + K +K A D+ T V
Sbjct: 876 YKESCVRLKELEKENKELVKRATIDIKTLV 905
Score = 66.6 bits (161), Expect = 5e-11
Identities = 100/433 (23%), Positives = 182/433 (42%), Gaps = 59/433 (13%)
Query: 113 EARTDPPDGQQDSECNRNKEKTLGKEVLLLMQALNTLSTPEEKLAALCKKYADLLEESRS 172
E +T D + + +K L KE L L L+ + + KK +L+EE+ +
Sbjct: 358 ETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDR---KKIEELMEENMT 414
Query: 173 VQKQMKILQKKQAQIVKEKVHLQSE-------------------HSKAILARSKLESLCR 213
L+ Q Q + E +HL E H L S+L L
Sbjct: 415 -------LEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEM 467
Query: 214 ELQRHNKTLKE---------ENMQQAREEEERRKEATAHFQITLDEIQAQLEQHDIHNAK 264
E Q KT++E N + + E+ + + +I +EI E+ + N +
Sbjct: 468 ENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQ--EKQSLQNCQ 525
Query: 265 -LRQENIELGEKLKKLIEQYALREEHIDKVFKRKELQQQLVDAKLQQTTQLIKEADEKH- 322
L ++ ++ +L+K IE E K+ +++ + L+Q +Q+ EA K
Sbjct: 526 NLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDI 585
Query: 323 QREREFLLKEATESRHKYEQMKQQEVQLKQQLSLYMDKFEEFQTT------MAKSNELFT 376
++E + L + E+ K +++ ++ Q+K++L Y +K E + + K NEL
Sbjct: 586 EKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQ 645
Query: 377 TFRQEMEKMTKKIKKLEKETIIWRTKWENNNKALLQMAEEKTVRDKEYKALQIKLERLEK 436
++ +KI+ LE+E ++ E N+ L +KT+ +K L +LE LEK
Sbjct: 646 KKITNLKITCEKIEALEQEN----SELERENRKL-----KKTL--DSFKNLTFQLESLEK 694
Query: 437 LCRALQTERNELNEKVEVLKEQVSIKAAIKAANRDLATPVMQPCTALDSHKELNTSSKRA 496
L E EL VE LK A ++ N++L + Q L+ K ++R
Sbjct: 695 ENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERL 754
Query: 497 LGAHLEAEPKSQR 509
++ + ++QR
Sbjct: 755 EVSYQGLDIENQR 767
Score = 55.1 bits (131), Expect = 2e-07
Identities = 84/366 (22%), Positives = 154/366 (42%), Gaps = 56/366 (15%)
Query: 148 TLSTPEEKLAALCKKYAD-------LLEESRSVQKQMKILQKKQAQ---------IVKEK 191
+L EEK+AAL + + L +E ++V+K + L+++Q + I E
Sbjct: 968 SLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGED 1027
Query: 192 VHLQSEHSKAILARSKLESLCRELQRHNKTLKEEN------MQQAREEEERRKEATAHFQ 245
+ E + K++ E++R+N TL+ E ++Q + + Q
Sbjct: 1028 NKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQ 1087
Query: 246 ITLDEIQAQLEQHDIHNAKLRQENIELG--------EKLKKLIEQYALREEHIDKVFKRK 297
+Q Q NAKL+ EN L + + LI+Q +L E+ + V K +
Sbjct: 1088 RQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENEN-ESVIKER 1146
Query: 298 ELQQQLVDAKLQQTTQLIKEADEKHQREREFLLKE--ATESRHKYEQMKQQEVQ------ 349
E + L D+ ++ +L + E+ E E L+ + +S HK +++ ++++
Sbjct: 1147 EDLKSLYDSLIKDHEKL-ELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQL 1205
Query: 350 LKQ--QLSLYMDKFEEFQTTMAKSNELFTTFRQEMEKMTKKIKKLE-------KETIIWR 400
LKQ QL + Q M N+ T E +K+ + +L KET + +
Sbjct: 1206 LKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKETEVLQ 1265
Query: 401 TKWEN-----NNKALLQ--MAEEKTVRDKEYKALQIKLERLEKLCRALQTERNELNEKVE 453
T +N NN L Q + E + ++Y+ L I +L C L + L E+
Sbjct: 1266 TDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENR 1325
Query: 454 VLKEQV 459
L +Q+
Sbjct: 1326 HLLDQI 1331
Score = 45.4 bits (106), Expect = 1e-04
Identities = 80/376 (21%), Positives = 147/376 (39%), Gaps = 89/376 (23%)
Query: 167 LEESRSVQKQMKILQKKQAQIVKEKVHLQSEHSKAIL--------------ARSKLESLC 212
+E + Q+ ++ L K A +K + + EHS+ I+ A S +S C
Sbjct: 176 MEVTDMSQEDIEPLLKNMALHLKRLIDERDEHSETIIELSEERDGLHFLPHASSSAQSPC 235
Query: 213 -------RELQRHNKTLKEENMQQAREEEERRKEATAHFQITLDEIQAQLEQHDIHNAKL 265
E ++H + + R + +E T L + + +LEQ +I +L
Sbjct: 236 GSPGMKRTESRQHLSVELADAKAKIRRLRQELEEKTEQ----LLDCKQELEQMEIELKRL 291
Query: 266 RQENIEL-----------------------GEKLKKLIEQYALREEHID----KVFKRKE 298
+QEN+ L +KL+ + +Y R I+ +V + KE
Sbjct: 292 QQENMNLLSDARSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKE 351
Query: 299 LQQQLVDAKLQQTTQL---IKEADEKHQREREFL-LK--------EATESRHKYEQMKQQ 346
Q L++ K QL +D+ H+ E+E L LK E R K E++ ++
Sbjct: 352 DNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEE 411
Query: 347 EVQLKQQLSLYMD-------KFEEFQTTMAKS-----------NELFTTFRQEMEKMTKK 388
+ L+ MD + E+ T S NEL ++ ++E +
Sbjct: 412 NMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQS 471
Query: 389 IKKLEKETIIWRTKWENNNKALLQMAEEKTVRDKEYKALQIK-------LERLEKLCRAL 441
+ K +E E N +L+M +E K+ + L+ + L+ + L + L
Sbjct: 472 LTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDL 531
Query: 442 QTERNELNEKVEVLKE 457
E+ +L + +E L+E
Sbjct: 532 MKEKAQLEKTIETLRE 547
Score = 44.3 bits (103), Expect = 3e-04
Identities = 60/294 (20%), Positives = 123/294 (41%), Gaps = 41/294 (13%)
Query: 135 LGKEVLLLMQALNTLSTPEEKL----AALCKKYADLLEESRSVQKQMKILQKKQAQIVKE 190
L ++ + L + TL T KL + L + L+ ++ + Q L+ + ++KE
Sbjct: 1086 LQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKE 1145
Query: 191 KVHLQS-------EHSKAILARSKLESLCRELQRHNKTLK-------------EENMQQA 230
+ L+S +H K L + S L + TLK E+ Q
Sbjct: 1146 REDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQL 1205
Query: 231 REEEERRKEATAHFQITLDEIQAQLEQHDIHNA---KLRQENIELGEKLKKLI-EQYALR 286
+++ + ++ ++ +++ + + H+ A KL EN L +L+ E L+
Sbjct: 1206 LKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKETEVLQ 1265
Query: 287 EEH--IDKVFKRKELQQQLVDA---KLQQTTQLIKEADEKHQREREFL------LKEATE 335
+H + + +L+Q ++A KL++ Q + K + E L L+E E
Sbjct: 1266 TDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEE--E 1323
Query: 336 SRHKYEQMKQQEVQLKQQLSLYMDKFEEFQTTMAKSNELFTTFRQEMEKMTKKI 389
+RH +Q++ +Q + L M+ + F + + R++ EK+ +KI
Sbjct: 1324 NRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNELRRQKEKLEEKI 1377
Score = 37.4 bits (85), Expect = 0.034
Identities = 41/198 (20%), Positives = 86/198 (43%), Gaps = 24/198 (12%)
Query: 285 LREEHIDKVFKRKELQ-QQLVDAKLQQTTQLIKEADEKHQREREFLLKEATESRHKYEQM 343
+ +E I+ + K L ++L+D + + + +I+ ++E+ FL ++ ++
Sbjct: 181 MSQEDIEPLLKNMALHLKRLIDERDEHSETIIELSEERDGLH--FLPHASSSAQSPCGSP 238
Query: 344 KQQEVQLKQQLSLYMD----KFEEFQTTMAKSNELFTTFRQEMEKMTKKIKKLEKETIIW 399
+ + +Q LS+ + K + + + E +QE+E+M ++K+L++E
Sbjct: 239 GMKRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQE---- 294
Query: 400 RTKWENNNKALLQMAEEKTVRDKEYKALQIKLERLEKLCRALQTERNELNE------KVE 453
N LL A + E AL+ K R++KL + + L++ +VE
Sbjct: 295 -------NMNLLSDARSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVE 347
Query: 454 VLKEQVSIKAAIKAANRD 471
LKE + K D
Sbjct: 348 ELKEDNQVLLETKTMLED 365
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 74.3 bits (181), Expect = 3e-13
Identities = 86/395 (21%), Positives = 176/395 (44%), Gaps = 51/395 (12%)
Query: 134 TLGKEVLLLMQALNTLSTPE--EKLAALCKKYADLLEESRSVQKQMKILQKK--QAQIVK 189
T ++ L L NT++ E EK A L +K + E +Q +K L++K +AQ++
Sbjct: 196 TKERDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLL 255
Query: 190 EKVHLQSEHSK-------------AILARSKLESLCRELQRHNKTLKEENMQQA------ 230
+ LQ E + A + ++L +L + Q +EE +Q+
Sbjct: 256 PQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCE 315
Query: 231 -----REEEER--RKEATAHFQITL-----DEIQAQLEQHDIHNAKLRQENIELGEKLKK 278
RE+EE+ R+E H Q D++ Q E+ K+R++ ++ + +K
Sbjct: 316 QELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEK 375
Query: 279 LIEQYALREEHIDKVFKRKEL---QQQLVDAKLQQTTQLIKEADEKHQREREFLLKEATE 335
+ EQ +E +++++++E Q++ K+ + + ++E DEK + + E + ++ +
Sbjct: 376 IREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEK 435
Query: 336 SRHKYEQMKQQEVQLKQQLSLYMDKFEEFQTTMAKSNELFTTFRQEMEKMTKKIKKLEKE 395
R E M+ QE +L++ ++ E+ Q K +++ EK ++ K L++E
Sbjct: 436 IRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQE 495
Query: 396 TIIWRTK----------WENNNKALLQMAEEKTVRDKE-YKALQIKLERLEKLCRALQTE 444
IW + WE K +Q EEK R +E + +++L + E+ + +
Sbjct: 496 EKIWEQEEKMWRQEEKMWEQEEK--MQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVR 553
Query: 445 RNELNEKVEVLKEQVSIKAAIKAANRDLATPVMQP 479
EL E++ L ++ + + P + P
Sbjct: 554 LQELEERLGKLGQKAELLGGAGRESGSQRLPTLTP 588
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 74.3 bits (181), Expect = 3e-13
Identities = 77/314 (24%), Positives = 156/314 (49%), Gaps = 22/314 (7%)
Query: 162 KYADLLEESRS-VQKQMKILQKKQAQIVKEKVHLQSEHSKAILARSKLESLCRELQRHNK 220
K+A LE++ S V Q K + ++ KE+ L E + + +L+ +LQ +
Sbjct: 233 KFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQ 292
Query: 221 TLKEENMQ-QAREEEERRKEATAHFQITLDEIQAQLE----QHDIHNAKLRQ--ENIELG 273
++ E + Q +E +RK A + ++QA+ + + +AKL+ E EL
Sbjct: 293 LVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELW 352
Query: 274 EKLKKLIEQYALREEHIDKVFKRKELQQQLVDAKLQQTTQLIKEADEKHQREREFLLKEA 333
+L + E+ R+E + ++ K +Q+Q + K+++ + I+E +EK +R+ E + ++
Sbjct: 353 NRLNQQQEEKMWRQEEKIQEWEEK-IQEQ--EEKIREQEEKIREQEEKMRRQEEMMWEKE 409
Query: 334 TESRHKYEQMKQQEVQLKQQLSLYMDKFEEFQTTMAKSNEL-----FTTFRQEMEKMTKK 388
+ R + E M ++E ++++Q + +K E+ + K +E RQE EK+ ++
Sbjct: 410 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQ 469
Query: 389 IKKLEKETIIWRTKWE-NNNKALLQMAEEKTVRDKEYKALQIKLERLEKLCRALQTERNE 447
K+ E+E +WR + + + ++ EEK R +E Q K+ EK + E+ E
Sbjct: 470 EKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEK-----RQEQEE 524
Query: 448 LNEKVEVLKEQVSI 461
+ + E ++EQ I
Sbjct: 525 MWRQEEKIREQEEI 538
Score = 70.9 bits (172), Expect = 3e-12
Identities = 72/359 (20%), Positives = 177/359 (49%), Gaps = 27/359 (7%)
Query: 122 QQDSECNRNKEKTLGKEVLLLMQALNTLSTPEEKLAALCKKYADLLEESRSVQKQMKILQ 181
Q+ E R +E+ + ++ + + + EEK+ ++ + E+ +++Q +++
Sbjct: 378 QEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMR---RQEEMMWEKEEKMRRQEEMMW 434
Query: 182 KKQAQI--VKEKVHLQSEHSKAILARSKLESLCRELQRHNKTLK--------EENMQQAR 231
+K+ +I ++EK+H Q + + R + E + + +R + K E ++ R
Sbjct: 435 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 494
Query: 232 EEEER--RKEATAHFQITLDEIQAQLEQHDI--HNAKLRQENIELGEKLKKLIEQYALRE 287
E+EE+ R+E H Q + E + + EQ ++ K+R++ E+ + +K+ EQ
Sbjct: 495 EQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQE-EIWRQKEKIHEQEEKIR 553
Query: 288 EHIDKVFKRKELQQQLVDAKLQQTTQLIKEADEKHQREREFLLKEATESRHKYEQMKQQE 347
+ +K+++++E K+ + I+E +EK R+ E + ++ + R + E++++QE
Sbjct: 554 KQEEKMWRQEE--------KMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQE 605
Query: 348 VQLKQQLSLYMDKFEEFQTTMAKSNELFTTFRQEMEKMTKKIKKLEKETIIWRTKWENNN 407
++Q ++ E+ K E R++ EK+ ++ KK+ ++ R + E
Sbjct: 606 EMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQ 665
Query: 408 KALLQMAEEKTVRDKEYKALQIKLERLEKLCRALQTERNELNEKVEVLKE-QVSIKAAI 465
+ +M E++ ++ + +Q + E++ + + + L ++ E ++E Q ++AAI
Sbjct: 666 EQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEAAI 724
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 73.6 bits (179), Expect = 4e-13
Identities = 84/375 (22%), Positives = 169/375 (45%), Gaps = 44/375 (11%)
Query: 143 MQALNTLSTPEEKLAALCKKYADLLEESRSVQKQMKILQKKQAQIVKEK----------- 191
++ L ++ EE++ A + E + + ++K L++K +Q+ +EK
Sbjct: 841 VKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAET 900
Query: 192 -VHLQSEHSKAILARSK--LESLCRELQRHNKTLKEENMQQAREEEERRKEATAHFQITL 248
++ ++E + LA K LE + E++ L+EE + + + ER+K A Q L
Sbjct: 901 ELYAEAEEMRVRLAAKKQELEEILHEMEAR---LEEEEDRGQQLQAERKKMA----QQML 953
Query: 249 DEIQAQLEQHDIHNAKLRQENIELGEKLKKLIEQYALREEHIDKVFKRKELQQQLVDAKL 308
D ++ QLE+ + KL+ E + K+KKL ++ + ++ +K+ K ++L ++ +
Sbjct: 954 D-LEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERIS--- 1009
Query: 309 QQTTQLIKEADE-----KHQREREFLLKEATESRHKYEQMKQQEVQLKQQLSLYMDKF-E 362
TT L +E ++ K + + E ++ E K E+ +Q+ +LK++L F E
Sbjct: 1010 DLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHE 1069
Query: 363 EFQTTMAKSNELFTTFRQEMEKMTKKIKKLEKETIIWRTKWENNNKALLQMAE-EKTVRD 421
+ A+ EL ++ E++ + +L+ E N AL ++ E E + D
Sbjct: 1070 QIADLQAQIAELKMQLAKKEEELQAALARLDDEI-------AQKNNALKKIRELEGHISD 1122
Query: 422 KEYKALQIKLERLEKLCRALQTERNELNEKVEVLKEQVSIKAAIKAANRDLATPVMQPCT 481
LQ L+ + ++ +L E++E LK ++ A ++L Q T
Sbjct: 1123 -----LQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVT 1177
Query: 482 ALDSHKELNTSSKRA 496
L + T S A
Sbjct: 1178 VLKKALDEETRSHEA 1192
Score = 58.5 bits (140), Expect = 1e-08
Identities = 50/227 (22%), Positives = 109/227 (48%), Gaps = 10/227 (4%)
Query: 131 KEKTLGKEVLLLMQALNTLSTPEEKLAALCKKYADLLEESRSVQKQMKILQKKQAQIVKE 190
+++ L +E+ + N L + +L A + A L EE Q M+ + + + ++
Sbjct: 1709 EKEELAEELASSLSGRNALQDEKRRLEA---RIAQLEEELEEEQGNMEAMSDRVRKATQQ 1765
Query: 191 KVHLQSEHSKAILARSKLESLCRELQRHNKTLKEENMQQAREEEERRKEATAHFQITLDE 250
L +E + K ES ++L+R NK L+ + + + + K A + + +
Sbjct: 1766 AEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQ 1825
Query: 251 IQAQLEQHDIHNAKLRQENIELGEKLKKLIEQYALREEHIDKVFKRKELQQQLVDAKLQQ 310
++ Q+EQ A+ +Q + ++ K +++ L+ E K+ ++ + Q + +A+++Q
Sbjct: 1826 LEEQVEQ----EAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQ 1881
Query: 311 TTQLIKEADEKHQR---EREFLLKEATESRHKYEQMKQQEVQLKQQL 354
+ ++EA+E+ QR R L +E E+ E M ++ LK +L
Sbjct: 1882 LKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKL 1928
Score = 56.2 bits (134), Expect = 7e-08
Identities = 74/408 (18%), Positives = 171/408 (41%), Gaps = 43/408 (10%)
Query: 149 LSTPEEKLAALCKKYADLLEESRSVQKQMKILQKKQAQIVKEKVHLQSEHSKAILARSKL 208
L+ EE+L A + D + + + K+++ L+ + + ++ L SE + AR+K
Sbjct: 1085 LAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQED---LDSERA----ARNKA 1137
Query: 209 ESLCRELQRHNKTLK---EENMQQAREEEERRKEATAHFQITLDEIQAQLEQHDIHNAKL 265
E R+L + LK E+ + ++E R + + + + H+ ++
Sbjct: 1138 EKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEM 1197
Query: 266 RQENIELGEKLKKLIEQYALREEHIDKVFKRKELQQQLVDAKLQQTTQLIKEADEKHQRE 325
RQ++ + E+L + +EQ+ + ++DK ++ L+++ +A L +++ +A ++ + +
Sbjct: 1198 RQKHAQAVEELTEQLEQFKRAKANLDK--NKQTLEKE--NADLAGELRVLGQAKQEVEHK 1253
Query: 326 REFLLKEATESRHKYEQMKQQEVQLKQQLSLYMDKFE---------------------EF 364
++ L + E + K ++ +L ++ ++ E
Sbjct: 1254 KKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASL 1313
Query: 365 QTTMAKSNELFTTFRQEMEKMTKKIKKLEKETIIWRTKWENNNKALLQMAEEKTVRDKEY 424
+ + + EL ++ ++ K+++LE+E + + + +A + + + +
Sbjct: 1314 SSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQL 1373
Query: 425 KALQIKLERLEKLCRALQTERNELNEKVEVLKEQVSIKAAI-----KAANRDLATPVMQP 479
+ KL+ AL+ + +++E L +Q KAA K NR L +
Sbjct: 1374 SDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNR-LQQELDDL 1432
Query: 480 CTALDSHKEL--NTSSKRALGAHLEAEPKSQRSAVQKPPSTGSAPAIE 525
LD+ ++L N K+ L AE K+ S A A E
Sbjct: 1433 VVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEARE 1480
Score = 54.3 bits (129), Expect = 3e-07
Identities = 89/453 (19%), Positives = 194/453 (42%), Gaps = 46/453 (10%)
Query: 89 ITENRNLVSPAYCTQESREEIPGGEARTDPPDGQQDSECNRNKEKTLGKEVLLLMQALNT 148
+ E +N +S Y + R E E T + E ++ L + +L +
Sbjct: 1457 LAEEKN-ISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMED 1515
Query: 149 LSTPEEKLAALCKKYADLLEESRSVQKQMKILQKKQAQIVKEKVHLQSEHSKAILARSKL 208
L + ++ + K +L + R+++ QM+ ++ + ++ E LQ+ + +
Sbjct: 1516 LVSSKDDVG---KNVHELEKSKRALETQMEEMKTQLEELEDE---LQATEDAKLRLEVNM 1569
Query: 209 ESLCRELQRHNKTLKEENMQQARE------------EEERRKEA-TAHFQITLDEIQAQL 255
++L + +R + E+N ++ R+ E+ER++ A A + L+ L
Sbjct: 1570 QALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDL 1629
Query: 256 EQHDIHNAKLRQENIELGEKLKKLIEQYALREEHI----DKVF---KRKELQQQLVDAKL 308
E K R+E I+ KL+ ++ + E D++F K E + + ++A L
Sbjct: 1630 ELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADL 1689
Query: 309 QQTTQLIKEADEKHQR---EREFLLKEATESRHKYEQMKQQEVQLKQQLSLYMDKFEEFQ 365
Q + + A+ ++ E+E L +E S ++ ++ +L+ +++ ++ EE Q
Sbjct: 1690 MQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQ 1749
Query: 366 TTMAKSNELFTTFRQEMEKMTKKIKKLEKETIIWRTKWENNNKALLQM-AEEKTVRDKEY 424
M ++ + K T++ ++L E R+ + N A Q+ + K +R K +
Sbjct: 1750 GNMEAMSD-------RVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLH 1802
Query: 425 KALQIKLERLEKLCRALQTERNELNEKVE-VLKEQVSIKAAIKAANRDLATPVMQ---PC 480
+ + + AL+ + +L E+VE +E+ + ++K ++ L ++Q
Sbjct: 1803 EMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDER 1862
Query: 481 TALDSHKEL----NTSSKRALGAHLEAEPKSQR 509
+ +KE N K+ EAE +SQR
Sbjct: 1863 KMAEQYKEQAEKGNARVKQLKRQLEEAEEESQR 1895
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 73.6 bits (179), Expect = 4e-13
Identities = 84/375 (22%), Positives = 169/375 (45%), Gaps = 44/375 (11%)
Query: 143 MQALNTLSTPEEKLAALCKKYADLLEESRSVQKQMKILQKKQAQIVKEK----------- 191
++ L ++ EE++ A + E + + ++K L++K +Q+ +EK
Sbjct: 848 VKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAET 907
Query: 192 -VHLQSEHSKAILARSK--LESLCRELQRHNKTLKEENMQQAREEEERRKEATAHFQITL 248
++ ++E + LA K LE + E++ L+EE + + + ER+K A Q L
Sbjct: 908 ELYAEAEEMRVRLAAKKQELEEILHEMEAR---LEEEEDRGQQLQAERKKMA----QQML 960
Query: 249 DEIQAQLEQHDIHNAKLRQENIELGEKLKKLIEQYALREEHIDKVFKRKELQQQLVDAKL 308
D ++ QLE+ + KL+ E + K+KKL ++ + ++ +K+ K ++L ++ +
Sbjct: 961 D-LEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERIS--- 1016
Query: 309 QQTTQLIKEADE-----KHQREREFLLKEATESRHKYEQMKQQEVQLKQQLSLYMDKF-E 362
TT L +E ++ K + + E ++ E K E+ +Q+ +LK++L F E
Sbjct: 1017 DLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHE 1076
Query: 363 EFQTTMAKSNELFTTFRQEMEKMTKKIKKLEKETIIWRTKWENNNKALLQMAE-EKTVRD 421
+ A+ EL ++ E++ + +L+ E N AL ++ E E + D
Sbjct: 1077 QIADLQAQIAELKMQLAKKEEELQAALARLDDEI-------AQKNNALKKIRELEGHISD 1129
Query: 422 KEYKALQIKLERLEKLCRALQTERNELNEKVEVLKEQVSIKAAIKAANRDLATPVMQPCT 481
LQ L+ + ++ +L E++E LK ++ A ++L Q T
Sbjct: 1130 -----LQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVT 1184
Query: 482 ALDSHKELNTSSKRA 496
L + T S A
Sbjct: 1185 VLKKALDEETRSHEA 1199
Score = 58.5 bits (140), Expect = 1e-08
Identities = 50/227 (22%), Positives = 109/227 (48%), Gaps = 10/227 (4%)
Query: 131 KEKTLGKEVLLLMQALNTLSTPEEKLAALCKKYADLLEESRSVQKQMKILQKKQAQIVKE 190
+++ L +E+ + N L + +L A + A L EE Q M+ + + + ++
Sbjct: 1716 EKEELAEELASSLSGRNALQDEKRRLEA---RIAQLEEELEEEQGNMEAMSDRVRKATQQ 1772
Query: 191 KVHLQSEHSKAILARSKLESLCRELQRHNKTLKEENMQQAREEEERRKEATAHFQITLDE 250
L +E + K ES ++L+R NK L+ + + + + K A + + +
Sbjct: 1773 AEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQ 1832
Query: 251 IQAQLEQHDIHNAKLRQENIELGEKLKKLIEQYALREEHIDKVFKRKELQQQLVDAKLQQ 310
++ Q+EQ A+ +Q + ++ K +++ L+ E K+ ++ + Q + +A+++Q
Sbjct: 1833 LEEQVEQ----EAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQ 1888
Query: 311 TTQLIKEADEKHQR---EREFLLKEATESRHKYEQMKQQEVQLKQQL 354
+ ++EA+E+ QR R L +E E+ E M ++ LK +L
Sbjct: 1889 LKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKL 1935
Score = 56.2 bits (134), Expect = 7e-08
Identities = 74/408 (18%), Positives = 171/408 (41%), Gaps = 43/408 (10%)
Query: 149 LSTPEEKLAALCKKYADLLEESRSVQKQMKILQKKQAQIVKEKVHLQSEHSKAILARSKL 208
L+ EE+L A + D + + + K+++ L+ + + ++ L SE + AR+K
Sbjct: 1092 LAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQED---LDSERA----ARNKA 1144
Query: 209 ESLCRELQRHNKTLK---EENMQQAREEEERRKEATAHFQITLDEIQAQLEQHDIHNAKL 265
E R+L + LK E+ + ++E R + + + + H+ ++
Sbjct: 1145 EKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEM 1204
Query: 266 RQENIELGEKLKKLIEQYALREEHIDKVFKRKELQQQLVDAKLQQTTQLIKEADEKHQRE 325
RQ++ + E+L + +EQ+ + ++DK ++ L+++ +A L +++ +A ++ + +
Sbjct: 1205 RQKHAQAVEELTEQLEQFKRAKANLDK--NKQTLEKE--NADLAGELRVLGQAKQEVEHK 1260
Query: 326 REFLLKEATESRHKYEQMKQQEVQLKQQLSLYMDKFE---------------------EF 364
++ L + E + K ++ +L ++ ++ E
Sbjct: 1261 KKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASL 1320
Query: 365 QTTMAKSNELFTTFRQEMEKMTKKIKKLEKETIIWRTKWENNNKALLQMAEEKTVRDKEY 424
+ + + EL ++ ++ K+++LE+E + + + +A + + + +
Sbjct: 1321 SSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQL 1380
Query: 425 KALQIKLERLEKLCRALQTERNELNEKVEVLKEQVSIKAAI-----KAANRDLATPVMQP 479
+ KL+ AL+ + +++E L +Q KAA K NR L +
Sbjct: 1381 SDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNR-LQQELDDL 1439
Query: 480 CTALDSHKEL--NTSSKRALGAHLEAEPKSQRSAVQKPPSTGSAPAIE 525
LD+ ++L N K+ L AE K+ S A A E
Sbjct: 1440 VVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEARE 1487
Score = 54.3 bits (129), Expect = 3e-07
Identities = 89/453 (19%), Positives = 194/453 (42%), Gaps = 46/453 (10%)
Query: 89 ITENRNLVSPAYCTQESREEIPGGEARTDPPDGQQDSECNRNKEKTLGKEVLLLMQALNT 148
+ E +N +S Y + R E E T + E ++ L + +L +
Sbjct: 1464 LAEEKN-ISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMED 1522
Query: 149 LSTPEEKLAALCKKYADLLEESRSVQKQMKILQKKQAQIVKEKVHLQSEHSKAILARSKL 208
L + ++ + K +L + R+++ QM+ ++ + ++ E LQ+ + +
Sbjct: 1523 LVSSKDDVG---KNVHELEKSKRALETQMEEMKTQLEELEDE---LQATEDAKLRLEVNM 1576
Query: 209 ESLCRELQRHNKTLKEENMQQARE------------EEERRKEA-TAHFQITLDEIQAQL 255
++L + +R + E+N ++ R+ E+ER++ A A + L+ L
Sbjct: 1577 QALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDL 1636
Query: 256 EQHDIHNAKLRQENIELGEKLKKLIEQYALREEHI----DKVF---KRKELQQQLVDAKL 308
E K R+E I+ KL+ ++ + E D++F K E + + ++A L
Sbjct: 1637 ELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADL 1696
Query: 309 QQTTQLIKEADEKHQR---EREFLLKEATESRHKYEQMKQQEVQLKQQLSLYMDKFEEFQ 365
Q + + A+ ++ E+E L +E S ++ ++ +L+ +++ ++ EE Q
Sbjct: 1697 MQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQ 1756
Query: 366 TTMAKSNELFTTFRQEMEKMTKKIKKLEKETIIWRTKWENNNKALLQM-AEEKTVRDKEY 424
M ++ + K T++ ++L E R+ + N A Q+ + K +R K +
Sbjct: 1757 GNMEAMSD-------RVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLH 1809
Query: 425 KALQIKLERLEKLCRALQTERNELNEKVE-VLKEQVSIKAAIKAANRDLATPVMQ---PC 480
+ + + AL+ + +L E+VE +E+ + ++K ++ L ++Q
Sbjct: 1810 EMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDER 1869
Query: 481 TALDSHKEL----NTSSKRALGAHLEAEPKSQR 509
+ +KE N K+ EAE +SQR
Sbjct: 1870 KMAEQYKEQAEKGNARVKQLKRQLEEAEEESQR 1902
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 73.6 bits (179), Expect = 4e-13
Identities = 84/375 (22%), Positives = 169/375 (45%), Gaps = 44/375 (11%)
Query: 143 MQALNTLSTPEEKLAALCKKYADLLEESRSVQKQMKILQKKQAQIVKEK----------- 191
++ L ++ EE++ A + E + + ++K L++K +Q+ +EK
Sbjct: 848 VKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAET 907
Query: 192 -VHLQSEHSKAILARSK--LESLCRELQRHNKTLKEENMQQAREEEERRKEATAHFQITL 248
++ ++E + LA K LE + E++ L+EE + + + ER+K A Q L
Sbjct: 908 ELYAEAEEMRVRLAAKKQELEEILHEMEAR---LEEEEDRGQQLQAERKKMA----QQML 960
Query: 249 DEIQAQLEQHDIHNAKLRQENIELGEKLKKLIEQYALREEHIDKVFKRKELQQQLVDAKL 308
D ++ QLE+ + KL+ E + K+KKL ++ + ++ +K+ K ++L ++ +
Sbjct: 961 D-LEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERIS--- 1016
Query: 309 QQTTQLIKEADE-----KHQREREFLLKEATESRHKYEQMKQQEVQLKQQLSLYMDKF-E 362
TT L +E ++ K + + E ++ E K E+ +Q+ +LK++L F E
Sbjct: 1017 DLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHE 1076
Query: 363 EFQTTMAKSNELFTTFRQEMEKMTKKIKKLEKETIIWRTKWENNNKALLQMAE-EKTVRD 421
+ A+ EL ++ E++ + +L+ E N AL ++ E E + D
Sbjct: 1077 QIADLQAQIAELKMQLAKKEEELQAALARLDDEI-------AQKNNALKKIRELEGHISD 1129
Query: 422 KEYKALQIKLERLEKLCRALQTERNELNEKVEVLKEQVSIKAAIKAANRDLATPVMQPCT 481
LQ L+ + ++ +L E++E LK ++ A ++L Q T
Sbjct: 1130 -----LQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVT 1184
Query: 482 ALDSHKELNTSSKRA 496
L + T S A
Sbjct: 1185 VLKKALDEETRSHEA 1199
Score = 58.5 bits (140), Expect = 1e-08
Identities = 50/227 (22%), Positives = 109/227 (48%), Gaps = 10/227 (4%)
Query: 131 KEKTLGKEVLLLMQALNTLSTPEEKLAALCKKYADLLEESRSVQKQMKILQKKQAQIVKE 190
+++ L +E+ + N L + +L A + A L EE Q M+ + + + ++
Sbjct: 1716 EKEELAEELASSLSGRNALQDEKRRLEA---RIAQLEEELEEEQGNMEAMSDRVRKATQQ 1772
Query: 191 KVHLQSEHSKAILARSKLESLCRELQRHNKTLKEENMQQAREEEERRKEATAHFQITLDE 250
L +E + K ES ++L+R NK L+ + + + + K A + + +
Sbjct: 1773 AEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQ 1832
Query: 251 IQAQLEQHDIHNAKLRQENIELGEKLKKLIEQYALREEHIDKVFKRKELQQQLVDAKLQQ 310
++ Q+EQ A+ +Q + ++ K +++ L+ E K+ ++ + Q + +A+++Q
Sbjct: 1833 LEEQVEQ----EAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQ 1888
Query: 311 TTQLIKEADEKHQR---EREFLLKEATESRHKYEQMKQQEVQLKQQL 354
+ ++EA+E+ QR R L +E E+ E M ++ LK +L
Sbjct: 1889 LKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKL 1935
Score = 56.2 bits (134), Expect = 7e-08
Identities = 74/408 (18%), Positives = 171/408 (41%), Gaps = 43/408 (10%)
Query: 149 LSTPEEKLAALCKKYADLLEESRSVQKQMKILQKKQAQIVKEKVHLQSEHSKAILARSKL 208
L+ EE+L A + D + + + K+++ L+ + + ++ L SE + AR+K
Sbjct: 1092 LAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQED---LDSERA----ARNKA 1144
Query: 209 ESLCRELQRHNKTLK---EENMQQAREEEERRKEATAHFQITLDEIQAQLEQHDIHNAKL 265
E R+L + LK E+ + ++E R + + + + H+ ++
Sbjct: 1145 EKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEM 1204
Query: 266 RQENIELGEKLKKLIEQYALREEHIDKVFKRKELQQQLVDAKLQQTTQLIKEADEKHQRE 325
RQ++ + E+L + +EQ+ + ++DK ++ L+++ +A L +++ +A ++ + +
Sbjct: 1205 RQKHAQAVEELTEQLEQFKRAKANLDK--NKQTLEKE--NADLAGELRVLGQAKQEVEHK 1260
Query: 326 REFLLKEATESRHKYEQMKQQEVQLKQQLSLYMDKFE---------------------EF 364
++ L + E + K ++ +L ++ ++ E
Sbjct: 1261 KKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASL 1320
Query: 365 QTTMAKSNELFTTFRQEMEKMTKKIKKLEKETIIWRTKWENNNKALLQMAEEKTVRDKEY 424
+ + + EL ++ ++ K+++LE+E + + + +A + + + +
Sbjct: 1321 SSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQL 1380
Query: 425 KALQIKLERLEKLCRALQTERNELNEKVEVLKEQVSIKAAI-----KAANRDLATPVMQP 479
+ KL+ AL+ + +++E L +Q KAA K NR L +
Sbjct: 1381 SDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNR-LQQELDDL 1439
Query: 480 CTALDSHKEL--NTSSKRALGAHLEAEPKSQRSAVQKPPSTGSAPAIE 525
LD+ ++L N K+ L AE K+ S A A E
Sbjct: 1440 VVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEARE 1487
Score = 54.3 bits (129), Expect = 3e-07
Identities = 89/453 (19%), Positives = 194/453 (42%), Gaps = 46/453 (10%)
Query: 89 ITENRNLVSPAYCTQESREEIPGGEARTDPPDGQQDSECNRNKEKTLGKEVLLLMQALNT 148
+ E +N +S Y + R E E T + E ++ L + +L +
Sbjct: 1464 LAEEKN-ISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMED 1522
Query: 149 LSTPEEKLAALCKKYADLLEESRSVQKQMKILQKKQAQIVKEKVHLQSEHSKAILARSKL 208
L + ++ + K +L + R+++ QM+ ++ + ++ E LQ+ + +
Sbjct: 1523 LVSSKDDVG---KNVHELEKSKRALETQMEEMKTQLEELEDE---LQATEDAKLRLEVNM 1576
Query: 209 ESLCRELQRHNKTLKEENMQQARE------------EEERRKEA-TAHFQITLDEIQAQL 255
++L + +R + E+N ++ R+ E+ER++ A A + L+ L
Sbjct: 1577 QALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDL 1636
Query: 256 EQHDIHNAKLRQENIELGEKLKKLIEQYALREEHI----DKVF---KRKELQQQLVDAKL 308
E K R+E I+ KL+ ++ + E D++F K E + + ++A L
Sbjct: 1637 ELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADL 1696
Query: 309 QQTTQLIKEADEKHQR---EREFLLKEATESRHKYEQMKQQEVQLKQQLSLYMDKFEEFQ 365
Q + + A+ ++ E+E L +E S ++ ++ +L+ +++ ++ EE Q
Sbjct: 1697 MQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQ 1756
Query: 366 TTMAKSNELFTTFRQEMEKMTKKIKKLEKETIIWRTKWENNNKALLQM-AEEKTVRDKEY 424
M ++ + K T++ ++L E R+ + N A Q+ + K +R K +
Sbjct: 1757 GNMEAMSD-------RVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLH 1809
Query: 425 KALQIKLERLEKLCRALQTERNELNEKVE-VLKEQVSIKAAIKAANRDLATPVMQ---PC 480
+ + + AL+ + +L E+VE +E+ + ++K ++ L ++Q
Sbjct: 1810 EMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDER 1869
Query: 481 TALDSHKEL----NTSSKRALGAHLEAEPKSQR 509
+ +KE N K+ EAE +SQR
Sbjct: 1870 KMAEQYKEQAEKGNARVKQLKRQLEEAEEESQR 1902
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 73.6 bits (179), Expect = 4e-13
Identities = 84/375 (22%), Positives = 169/375 (45%), Gaps = 44/375 (11%)
Query: 143 MQALNTLSTPEEKLAALCKKYADLLEESRSVQKQMKILQKKQAQIVKEK----------- 191
++ L ++ EE++ A + E + + ++K L++K +Q+ +EK
Sbjct: 841 VKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAET 900
Query: 192 -VHLQSEHSKAILARSK--LESLCRELQRHNKTLKEENMQQAREEEERRKEATAHFQITL 248
++ ++E + LA K LE + E++ L+EE + + + ER+K A Q L
Sbjct: 901 ELYAEAEEMRVRLAAKKQELEEILHEMEAR---LEEEEDRGQQLQAERKKMA----QQML 953
Query: 249 DEIQAQLEQHDIHNAKLRQENIELGEKLKKLIEQYALREEHIDKVFKRKELQQQLVDAKL 308
D ++ QLE+ + KL+ E + K+KKL ++ + ++ +K+ K ++L ++ +
Sbjct: 954 D-LEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERIS--- 1009
Query: 309 QQTTQLIKEADE-----KHQREREFLLKEATESRHKYEQMKQQEVQLKQQLSLYMDKF-E 362
TT L +E ++ K + + E ++ E K E+ +Q+ +LK++L F E
Sbjct: 1010 DLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHE 1069
Query: 363 EFQTTMAKSNELFTTFRQEMEKMTKKIKKLEKETIIWRTKWENNNKALLQMAE-EKTVRD 421
+ A+ EL ++ E++ + +L+ E N AL ++ E E + D
Sbjct: 1070 QIADLQAQIAELKMQLAKKEEELQAALARLDDEI-------AQKNNALKKIRELEGHISD 1122
Query: 422 KEYKALQIKLERLEKLCRALQTERNELNEKVEVLKEQVSIKAAIKAANRDLATPVMQPCT 481
LQ L+ + ++ +L E++E LK ++ A ++L Q T
Sbjct: 1123 -----LQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVT 1177
Query: 482 ALDSHKELNTSSKRA 496
L + T S A
Sbjct: 1178 VLKKALDEETRSHEA 1192
Score = 58.5 bits (140), Expect = 1e-08
Identities = 50/227 (22%), Positives = 109/227 (48%), Gaps = 10/227 (4%)
Query: 131 KEKTLGKEVLLLMQALNTLSTPEEKLAALCKKYADLLEESRSVQKQMKILQKKQAQIVKE 190
+++ L +E+ + N L + +L A + A L EE Q M+ + + + ++
Sbjct: 1709 EKEELAEELASSLSGRNALQDEKRRLEA---RIAQLEEELEEEQGNMEAMSDRVRKATQQ 1765
Query: 191 KVHLQSEHSKAILARSKLESLCRELQRHNKTLKEENMQQAREEEERRKEATAHFQITLDE 250
L +E + K ES ++L+R NK L+ + + + + K A + + +
Sbjct: 1766 AEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQ 1825
Query: 251 IQAQLEQHDIHNAKLRQENIELGEKLKKLIEQYALREEHIDKVFKRKELQQQLVDAKLQQ 310
++ Q+EQ A+ +Q + ++ K +++ L+ E K+ ++ + Q + +A+++Q
Sbjct: 1826 LEEQVEQ----EAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQ 1881
Query: 311 TTQLIKEADEKHQR---EREFLLKEATESRHKYEQMKQQEVQLKQQL 354
+ ++EA+E+ QR R L +E E+ E M ++ LK +L
Sbjct: 1882 LKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKL 1928
Score = 56.2 bits (134), Expect = 7e-08
Identities = 74/408 (18%), Positives = 171/408 (41%), Gaps = 43/408 (10%)
Query: 149 LSTPEEKLAALCKKYADLLEESRSVQKQMKILQKKQAQIVKEKVHLQSEHSKAILARSKL 208
L+ EE+L A + D + + + K+++ L+ + + ++ L SE + AR+K
Sbjct: 1085 LAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQED---LDSERA----ARNKA 1137
Query: 209 ESLCRELQRHNKTLK---EENMQQAREEEERRKEATAHFQITLDEIQAQLEQHDIHNAKL 265
E R+L + LK E+ + ++E R + + + + H+ ++
Sbjct: 1138 EKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEM 1197
Query: 266 RQENIELGEKLKKLIEQYALREEHIDKVFKRKELQQQLVDAKLQQTTQLIKEADEKHQRE 325
RQ++ + E+L + +EQ+ + ++DK ++ L+++ +A L +++ +A ++ + +
Sbjct: 1198 RQKHAQAVEELTEQLEQFKRAKANLDK--NKQTLEKE--NADLAGELRVLGQAKQEVEHK 1253
Query: 326 REFLLKEATESRHKYEQMKQQEVQLKQQLSLYMDKFE---------------------EF 364
++ L + E + K ++ +L ++ ++ E
Sbjct: 1254 KKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASL 1313
Query: 365 QTTMAKSNELFTTFRQEMEKMTKKIKKLEKETIIWRTKWENNNKALLQMAEEKTVRDKEY 424
+ + + EL ++ ++ K+++LE+E + + + +A + + + +
Sbjct: 1314 SSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQL 1373
Query: 425 KALQIKLERLEKLCRALQTERNELNEKVEVLKEQVSIKAAI-----KAANRDLATPVMQP 479
+ KL+ AL+ + +++E L +Q KAA K NR L +
Sbjct: 1374 SDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNR-LQQELDDL 1432
Query: 480 CTALDSHKEL--NTSSKRALGAHLEAEPKSQRSAVQKPPSTGSAPAIE 525
LD+ ++L N K+ L AE K+ S A A E
Sbjct: 1433 VVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEARE 1480
Score = 54.3 bits (129), Expect = 3e-07
Identities = 89/453 (19%), Positives = 194/453 (42%), Gaps = 46/453 (10%)
Query: 89 ITENRNLVSPAYCTQESREEIPGGEARTDPPDGQQDSECNRNKEKTLGKEVLLLMQALNT 148
+ E +N +S Y + R E E T + E ++ L + +L +
Sbjct: 1457 LAEEKN-ISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMED 1515
Query: 149 LSTPEEKLAALCKKYADLLEESRSVQKQMKILQKKQAQIVKEKVHLQSEHSKAILARSKL 208
L + ++ + K +L + R+++ QM+ ++ + ++ E LQ+ + +
Sbjct: 1516 LVSSKDDVG---KNVHELEKSKRALETQMEEMKTQLEELEDE---LQATEDAKLRLEVNM 1569
Query: 209 ESLCRELQRHNKTLKEENMQQARE------------EEERRKEA-TAHFQITLDEIQAQL 255
++L + +R + E+N ++ R+ E+ER++ A A + L+ L
Sbjct: 1570 QALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDL 1629
Query: 256 EQHDIHNAKLRQENIELGEKLKKLIEQYALREEHI----DKVF---KRKELQQQLVDAKL 308
E K R+E I+ KL+ ++ + E D++F K E + + ++A L
Sbjct: 1630 ELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADL 1689
Query: 309 QQTTQLIKEADEKHQR---EREFLLKEATESRHKYEQMKQQEVQLKQQLSLYMDKFEEFQ 365
Q + + A+ ++ E+E L +E S ++ ++ +L+ +++ ++ EE Q
Sbjct: 1690 MQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQ 1749
Query: 366 TTMAKSNELFTTFRQEMEKMTKKIKKLEKETIIWRTKWENNNKALLQM-AEEKTVRDKEY 424
M ++ + K T++ ++L E R+ + N A Q+ + K +R K +
Sbjct: 1750 GNMEAMSD-------RVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLH 1802
Query: 425 KALQIKLERLEKLCRALQTERNELNEKVE-VLKEQVSIKAAIKAANRDLATPVMQ---PC 480
+ + + AL+ + +L E+VE +E+ + ++K ++ L ++Q
Sbjct: 1803 EMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDER 1862
Query: 481 TALDSHKEL----NTSSKRALGAHLEAEPKSQR 509
+ +KE N K+ EAE +SQR
Sbjct: 1863 KMAEQYKEQAEKGNARVKQLKRQLEEAEEESQR 1895
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 73.2 bits (178), Expect = 6e-13
Identities = 86/410 (20%), Positives = 178/410 (43%), Gaps = 47/410 (11%)
Query: 131 KEKTLGKEVLLLMQALNTLSTPEEKLAALCKKYADLLEESRSVQKQMKILQKKQAQIVKE 190
KE G+ L ++ S E++ A ++ A +E ++ +Q K +K+ ++E
Sbjct: 801 KEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLRE 860
Query: 191 KVHLQSEHSKAILARSKLESLCRELQRHNKTLKEENMQ----QAREEEERRKEATAHFQI 246
K + + LA++ LESL RE LKE+ + QA+ EEER + +A Q+
Sbjct: 861 KWEKERSWHQQELAKA-LESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQM 919
Query: 247 TLDEIQAQLEQHDIHNAKLRQENIELGEKLKKLIEQYALREEHIDKVFKRKELQQQLVDA 306
L+ +E + L E L + ++ A + ++++ + ++Q+
Sbjct: 920 QLET---------------EKERVSLLETLLQTQKELADASQQLERLRQDMKVQK----L 960
Query: 307 KLQQTTQLIKEADEKHQREREFLLKEATESRHKYEQMKQQEVQLKQQLSLYMDKFEEFQT 366
K Q+TT +++ ++ QRE L + A + R ++++ L Q + E+ ++
Sbjct: 961 KEQETTGILQTQLQEAQRE---LKEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKS 1017
Query: 367 TMAKSNELFTTFRQEMEKMTKKI-------KKLEKETIIWRTKWENNNKALLQMAEEKTV 419
+ ++ QE+++ ++ K+LE+E + LL + E ++
Sbjct: 1018 QLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSI 1077
Query: 420 RDKEYKALQIKLERLEKLCRALQTERNELNEKVEVLKEQVSIKAAIKAANRDLATPVMQP 479
R +E AL+ ++ Q E+ EL+ ++E+L+++V K A A ++
Sbjct: 1078 RQQELSALRQDMQE-------AQGEQKELSAQMELLRQEVKEKEADFLAQEAQLLEELEA 1130
Query: 480 CTALDSHKELNTSSKRALGAHLEAEPKSQRS------AVQKPPSTGSAPA 523
+ + ++ A A L+ +S S A Q+P + A A
Sbjct: 1131 SHITEQQLRASLWAQEAKAAQLQLRLRSTESQLEALAAEQQPGNQAQAQA 1180
Score = 65.9 bits (159), Expect = 9e-11
Identities = 84/356 (23%), Positives = 159/356 (44%), Gaps = 37/356 (10%)
Query: 149 LSTPEEKLAALCKKYADLLEESRSVQKQMKILQKKQAQIVKE-KVHLQSEHSKAILARSK 207
L+ ++ AL + DL ESR +K + LQ++ A+ +E +V ++ + A++
Sbjct: 1875 LAVEGRRVQALEEVLGDLRAESREQEKALLALQQQCAEQAQEHEVETRALQDSWLQAQAV 1934
Query: 208 LESLCRELQRHNKTLKEENMQQAREEEERRKEATAHFQITLDEIQAQL---EQHDIHNAK 264
L+ +EL+ L+ E+ +EE R A A Q L + A L EQH + A+
Sbjct: 1935 LKERDQELE----ALRAESQSSRHQEEAARARAEA-LQEALGKAHAALQGKEQHLLEQAE 1989
Query: 265 LRQENIELGEKLKKLIEQYALREEHIDKVFKRKELQQQLVDAKLQQTTQLIKEA----DE 320
L + L+ ++ +++ + +E + Q D + Q+ Q +++A DE
Sbjct: 1990 LSRSLEASTATLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQEDVQQLQQALAQRDE 2049
Query: 321 --KHQREREFLLKEATESRHKYEQMKQQEVQLKQQLSLYMDKFEEFQTTMAKSNELFTTF 378
+HQ+ERE LL+++ R +++ +Q KQ L ++ EE + EL T
Sbjct: 2050 ELRHQQEREQLLEKSLAQR-----VQENMIQEKQNLGQEREE-EEIRGLHQSVRELQLTL 2103
Query: 379 RQEMEKMTKKIKKLEKETIIWRTKWENNNKAL------LQMAEEKTVRDKEYKALQIKLE 432
Q+ +++ + + T+ NN +AL M E+ D LQ +LE
Sbjct: 2104 AQKEQEILE----------LRETQQRNNLEALPHSHKTSPMEEQSLKLDSLEPRLQRELE 2153
Query: 433 RLEKLCRALQTERNELNEKVEVLKEQVSIKAAIKAANRDLATPVMQPCTALDSHKE 488
RL+ R + E EK + L ++ A ++ +++A + DS ++
Sbjct: 2154 RLQAALRQTEAREIEWREKAQDLALSLAQTKASVSSLQEVAMFLQASVLERDSEQQ 2209
Score = 59.3 bits (142), Expect = 8e-09
Identities = 93/423 (21%), Positives = 181/423 (42%), Gaps = 64/423 (15%)
Query: 130 NKEKTLGKEVLLLMQALNTLSTPEEKLA----ALCKKYADLLEESRSVQKQMKILQ---- 181
+ E TL EV L A LS E LA L ++ L EE++SV +M+ +
Sbjct: 582 SSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARN 641
Query: 182 ----------KKQAQIVKEKVHLQSEHSKAILARSKLESLCRELQ-------------RH 218
K++ + ++ HL+++ KA A ++L++ R++Q RH
Sbjct: 642 ALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRH 701
Query: 219 NKTLKEENMQQAREEEERRKEATAHFQITLDEIQAQLEQHDIHNAKLRQENIELGEKLKK 278
+ ++Q +E +R++E A + + + ++ + ++ +L E+L+
Sbjct: 702 QQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQG 761
Query: 279 LIEQYALREEHIDKVFKRKELQQQLVDAKLQQTTQLIKEADEKHQREREFLLKEATESRH 338
L L E + + ++ + ++ +L+ Q + +A E Q E L E R
Sbjct: 762 LSSAKELLESSLFEAQQQNSV-IEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERS 820
Query: 339 KYEQ-------------------MKQQEVQLKQQLSLYMDKFEE----FQTTMAKSNELF 375
+ EQ ++QQ+ +++++ +K+E+ Q +AK+ E
Sbjct: 821 QAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESL 880
Query: 376 TTFRQEMEKMTKKIKKLEKETIIWRTKWENN--NKALLQMAEEKTVRDKEYKALQIKLER 433
+ E+E M K ++ E E I + + E AL QM E + L+ L+
Sbjct: 881 EREKMELE-MRLKEQQTEMEAIQAQREEERTQAESALCQMQLE--TEKERVSLLETLLQT 937
Query: 434 LEKLCRA-LQTERNELNEKVEVLKEQVS---IKAAIKAANRDLATPVMQPCTALDSHKEL 489
++L A Q ER + KV+ LKEQ + ++ ++ A R+L Q L + +E
Sbjct: 938 QKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLAALQEE 997
Query: 490 NTS 492
++S
Sbjct: 998 SSS 1000
Score = 58.5 bits (140), Expect = 1e-08
Identities = 100/436 (22%), Positives = 188/436 (43%), Gaps = 70/436 (16%)
Query: 104 ESREEIPGGEARTDPPDGQQDSECNRNKEKTLGKEVLLLMQALNTLSTPEEKLAALCKKY 163
ESR E+ GG D E ++N ++L K LL T + E +AL K +
Sbjct: 1198 ESRPELSGGG---DSAPSVWGLEPDQNGARSLFKRGPLL-----TALSAEAVASALHKLH 1249
Query: 164 ADLLEESRSVQKQMKILQKKQAQIVKEKVHLQSEHSKAILARSKLESLCREL-QRHNKTL 222
DL + +Q + + + Q Q ++E+ L ++ ++L+ L R+L Q +
Sbjct: 1250 QDLWKT-----QQTRDVLRDQVQKLEER--LTDTEAEKSQVHTELQDLQRQLSQNQEEKS 1302
Query: 223 KEENMQQAREEEERRKEATAHFQITLDEIQAQLEQHDIHNAKLRQENIELGEKLKKLIEQ 282
K E Q + E E T+ +Q++L + ++ + + E E L+ E
Sbjct: 1303 KWEGKQNSLESE------LMELHETMASLQSRLRRAELQRMEAQGER----ELLQAAKEN 1352
Query: 283 YALREEHIDKVFKRKELQQQLVDAKLQQTTQLIKEADEKHQREREFLLKEATESRHKYEQ 342
+ EH LQ +V+A+ Q + I E D + R L E ES + Q
Sbjct: 1353 LTAQVEH---------LQAAVVEARAQASAAGILEEDLRTARSALKLKNEEVESERERAQ 1403
Query: 343 MKQQEVQLKQQLSLYMDKFEEFQTTMAKSNELFTTFRQEMEKMTKKIKKLEKETIIWRTK 402
Q++ +LK + + + Q +A + +E+E + +I++LEK+ + +
Sbjct: 1404 ALQEQGELK------VAQGKALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAA 1457
Query: 403 WE--------NNNKALLQMAE----EK----------TVRDKEYKALQIKLERLEKLCRA 440
E N + LQ + EK V+++E K L ++ E++ +L +
Sbjct: 1458 LELLSLDLKKRNQEVDLQQEQIQELEKCRSVLEHLPMAVQEREQK-LTVQREQIRELEKD 1516
Query: 441 LQTERNELNEKVEVLKEQVSIKAAIKAANRDLATP-VMQPCTAL---DSHKELNTSSKRA 496
+T+RN L ++ L+++ + + + +DL V C AL ++H ++ K
Sbjct: 1517 RETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALELEENHHKMECQQK-- 1574
Query: 497 LGAHLEAEPKSQRSAV 512
L LE + ++QR A+
Sbjct: 1575 LIKELEGQRETQRVAL 1590
Score = 56.6 bits (135), Expect = 5e-08
Identities = 80/364 (21%), Positives = 165/364 (45%), Gaps = 53/364 (14%)
Query: 153 EEKLAALCKKYADLLEESRSVQK-----QMKILQKKQAQIVKEKVHLQSEHSKAILARSK 207
E+KL ++ +L E+ R Q+ Q+ L+KK I ++ +Q + +
Sbjct: 1500 EQKLTVQREQIREL-EKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVT---- 1554
Query: 208 LESLCRELQR--HNKTLKEENMQQAREEEERRKEATAHFQITLDE----IQAQLEQ-HDI 260
LE L EL+ H +++ +++ + E ++ A H + L+E +QAQ Q HD+
Sbjct: 1555 LECLALELEENHHKMECQQKLIKELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDL 1614
Query: 261 --HNAKLRQENIELGEKLK---KLIEQYALREEHIDKVFKR--------KELQQQLVDAK 307
H+ L +E E +++K + IE+ ++EH+ + +R KE Q L D +
Sbjct: 1615 ESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLERRDQELMLQKERIQVLEDQR 1674
Query: 308 LQQTTQL----------IKEADEKHQREREFLLKEATESRHKYEQMKQQEVQLKQQLSLY 357
+QT L ++E + +R+ + + A E + K Q L+ +
Sbjct: 1675 TRQTKILEEDLEQIKLSLRERGRELTTQRQLMQERAEEGK---GPSKAQRGSLEHMKLIL 1731
Query: 358 MDKFEEFQTTMAKSNELFTTFRQEMEKMTKKIKKLEKETIIWRTKWENNNKALLQMAEE- 416
DK +E + +EL + ++E+ + + + ET + ++ E L Q +E
Sbjct: 1732 RDKEKEVECQQEHIHEL-QELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEA 1790
Query: 417 KTVRDKEYKALQIKLERLEKL-------CRALQTERNELNEKVEVLKEQV-SIKAAIKAA 468
+ + + ++LQ +L+ ++ ALQ E+ + + E +KE+ +++ A++ A
Sbjct: 1791 REQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQA 1850
Query: 469 NRDL 472
+ L
Sbjct: 1851 HMTL 1854
Score = 51.6 bits (122), Expect = 2e-06
Identities = 66/346 (19%), Positives = 156/346 (45%), Gaps = 38/346 (10%)
Query: 153 EEKLAALCKKYADLLEESRSVQKQMKILQKKQAQIVKEKVHLQSEHSKAILARSKLESLC 212
E L ++ + +E +S ++Q++ LQ+++ + ++ L+ + +L + +++ L
Sbjct: 1615 ESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQD---LERRDQELMLQKERIQVLE 1671
Query: 213 RELQRHNKTLKEENMQQAREEEERRKEATAHFQITLDEIQAQLEQHDIHNAKLRQENIEL 272
+ R K L+E+ Q ER +E T Q+ + + L + L
Sbjct: 1672 DQRTRQTKILEEDLEQIKLSLRERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLIL 1731
Query: 273 GEKLKKLIEQYALREEHIDKVFKRKE-LQQQL--VDAKLQQTTQLIKEADEK-------- 321
+K K++ ++EHI ++ + K+ L+QQL + K+ +T+ L+ + +++
Sbjct: 1732 RDKEKEV----ECQQEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQL 1787
Query: 322 -HQREREFLLKEATESR------------HKYEQMKQQEVQLKQQLSLYMDKFEEFQTTM 368
RE+ L +++ +S+ + E ++Q++ Q + Q +K + Q +
Sbjct: 1788 QEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGAL 1847
Query: 369 AKSNELFTTFRQEMEKMTKKIKKLEKETIIWRTKWENNNKALLQMAEEKTVRDKEYKALQ 428
+++ E++ ++ ++LE+E + + + + L + E ++K ALQ
Sbjct: 1848 EQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKALLALQ 1907
Query: 429 ----IKLERLEKLCRALQTERNELNEKVEVLKEQVSIKAAIKAANR 470
+ + E RALQ + + VLKE+ A++A ++
Sbjct: 1908 QQCAEQAQEHEVETRALQ---DSWLQAQAVLKERDQELEALRAESQ 1950
Score = 47.4 bits (111), Expect = 3e-05
Identities = 73/385 (18%), Positives = 157/385 (40%), Gaps = 25/385 (6%)
Query: 154 EKLAALCKKYADLLEESRSVQKQMKILQKKQAQIVKEKVHLQSEHSKAILARSKLESLCR 213
E + L + +L+E S+ + + + Q++K+ + E I S E+
Sbjct: 311 ETVEILETNHTELMEHEASLSRNAQEEKLSLQQVIKDITQVMVEEGDNIAQGSGHENSLE 370
Query: 214 ---------ELQRHNK--TLKEENMQQAREEEERRKEATAHFQITLDEIQAQLEQHDIHN 262
+ Q +K TL + + R+ + ++ A Q ++ +Q Q +Q +
Sbjct: 371 LDSSIFSQFDYQDADKALTLVRSVLTRRRQAVQDLRQQLAGCQEAVNLLQQQHDQWEEEG 430
Query: 263 AKLRQENIELGEKLKKLIEQYALREEHIDKVFKRKELQQQLVDAKLQQTTQLIKEADEKH 322
LRQ +L + L Q + +D + K +EL Q+ + QQ L +EA
Sbjct: 431 KALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQLEVLEQEAWRLR 490
Query: 323 QREREFLLKEATESRHKYEQMKQQEVQLKQQLSLYMDKFEEFQTTMAKSNELFTTFRQEM 382
+ E L+ + K EQ ++ + ++++ L + + ++S T R+ +
Sbjct: 491 RVNVELQLQGDSAQGQKEEQQEELHLAVRERERL-QEMLMGLEAKQSESLSELITLREAL 549
Query: 383 EKMTKKIKKLEKETIIWRTKWENNNKALLQMAEEKTVRDKEYKALQIKLERLEKLCRALQ 442
E + + L +E +++ +++ + E L+ +L L AL
Sbjct: 550 ESSHLEGELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALA 609
Query: 443 TERNELNEKVEVLKEQ-VSIKAAIKAANR-------DLATPV--MQPCTALDSHKELNTS 492
++ LN+++ L+E+ S+ + ++AA + DLA + ++H E
Sbjct: 610 LDKVGLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQ 669
Query: 493 SKRALGAHLEAEPK---SQRSAVQK 514
GA L+A+ + ++ +QK
Sbjct: 670 KAEEAGAELQADLRDIQEEKEEIQK 694
Score = 46.2 bits (108), Expect = 7e-05
Identities = 85/396 (21%), Positives = 158/396 (39%), Gaps = 53/396 (13%)
Query: 129 RNKEKTLGKEVLLLMQALNTLSTP----EEKLAALCKKYADLLEESRSVQKQMKILQKKQ 184
R + L +++ +A+N L EE+ AL ++ L E ++ Q LQ +
Sbjct: 399 RQAVQDLRQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEV 458
Query: 185 AQIVKEKVHLQSEHSKAILARSKLESLCRELQRHNKTLKEENMQQAREEEERRKEATAHF 244
+ KE+ LQ + LE L+R N L+ + ++EE+++E H
Sbjct: 459 DSLSKERELLQKAREELRQQLEVLEQEAWRLRRVNVELQLQGDSAQGQKEEQQEE--LHL 516
Query: 245 QI-TLDEIQAQLEQHDIHNAKLRQENIELGEKLKKL-IEQYALREEHIDKVFKRKELQQQ 302
+ + +Q L + ++ E I L E L+ +E LR+E + +Q
Sbjct: 517 AVRERERLQEMLMGLEAKQSESLSELITLREALESSHLEGELLRQEQTEVTAALARAEQS 576
Query: 303 LVDAKLQQTTQLIKEADEKHQREREFLLKEATESRHKYEQMKQQEVQLKQQLSLYMDKFE 362
+ + + T + AD + + L EA + +V L QQL ++ +
Sbjct: 577 IAELSSSENTLKTEVADLRAAAVKLSALNEA---------LALDKVGLNQQLLQLEEENQ 627
Query: 363 EFQTTMAKSNELFTTFRQEMEKMTKKIKKLEKETIIWRTKWENNN--KALLQMAEE---- 416
+ M + + + ++ + K+ + L WE N +A LQ AEE
Sbjct: 628 SVCSRMEAAEQARNALQVDLAEAEKRREAL----------WEKNTHLEAQLQKAEEAGAE 677
Query: 417 --KTVRD--KEYKALQIKLERLEKLCRALQTERNELN---------------EKVEVLKE 457
+RD +E + +Q KL A T+ +L+ EK +++E
Sbjct: 678 LQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVRE 737
Query: 458 QVSIKAAIKAANRDLATPVMQPCTALDSHKELNTSS 493
+ +++ ++A RD + + L S KEL SS
Sbjct: 738 KAALEVRLQAVERD-RQDLAEQLQGLSSAKELLESS 772
Score = 45.8 bits (107), Expect = 1e-04
Identities = 48/230 (20%), Positives = 107/230 (46%), Gaps = 22/230 (9%)
Query: 126 ECNRNKEKTLGKEVLLLMQALNTLSTPEEKLAALCKKYADLLEESRSVQKQMKILQKKQA 185
+ R +E+T + L MQ L T +E+++ LLE QK++ ++
Sbjct: 902 QAQREEERTQAESALCQMQ----LETEKERVS--------LLETLLQTQKELADASQQLE 949
Query: 186 QIVKE-KVHLQSEHSKAILARSKLESLCRELQRHNKTLKEENMQQAREEEERRKEATAHF 244
++ ++ KV E + +++L+ REL+ + +++ + +EE +
Sbjct: 950 RLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRDD-LAALQEESSSLLQDKMDL 1008
Query: 245 QITLDEIQAQLEQHDIHNAKLRQENIELGEKLKKLIEQYALREEHIDKVFKRKELQQQLV 304
Q ++++++QL D + QE + EKL++ E I K +R++ L
Sbjct: 1009 QKQVEDLKSQLVAQDDSQRLVEQE---VQEKLRETQEY-----NRIQKELEREKASLTLS 1060
Query: 305 DAKLQQTTQLIKEADEKHQREREFLLKEATESRHKYEQMKQQEVQLKQQL 354
+ +Q +++EAD Q+E L ++ E++ + +++ Q L+Q++
Sbjct: 1061 LMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQMELLRQEV 1110
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 73.2 bits (178), Expect = 6e-13
Identities = 83/382 (21%), Positives = 171/382 (44%), Gaps = 51/382 (13%)
Query: 147 NTLSTPE--EKLAALCKKYADLLEESRSVQKQMKILQKK--QAQIVKEKVHLQSEHSK-- 200
NT++ E EK A L +K + E +Q +K L++K +AQ++ + LQ E +
Sbjct: 209 NTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLG 268
Query: 201 -----------AILARSKLESLCRELQRHNKTLKEENMQQA-----------REEEER-- 236
A + ++L +L + Q +EE +Q+ RE+EE+
Sbjct: 269 KELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMW 328
Query: 237 RKEATAHFQITL-----DEIQAQLEQHDIHNAKLRQENIELGEKLKKLIEQYALREEHID 291
R+E H Q D++ Q E+ K+R++ ++ + +K+ EQ +E +
Sbjct: 329 RQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEE 388
Query: 292 KVFKRKEL---QQQLVDAKLQQTTQLIKEADEKHQREREFLLKEATESRHKYEQMKQQEV 348
++++++E Q++ K+ + + ++E DEK + + E + ++ + R E M+ QE
Sbjct: 389 EMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEE 448
Query: 349 QLKQQLSLYMDKFEEFQTTMAKSNELFTTFRQEMEKMTKKIKKLEKETIIWRTK------ 402
+L++ ++ E+ Q K +++ EK ++ K L++E IW +
Sbjct: 449 KLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQ 508
Query: 403 ----WENNNKALLQMAEEKTVRDKE-YKALQIKLERLEKLCRALQTERNELNEKVEVLKE 457
WE K +Q EEK R +E + +++L + E+ + + EL E++ L +
Sbjct: 509 EEKMWEQEEK--MQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQ 566
Query: 458 QVSIKAAIKAANRDLATPVMQP 479
+ + + P + P
Sbjct: 567 KAELLGGAGRESGSQRLPTLTP 588
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 72.4 bits (176), Expect = 1e-12
Identities = 75/359 (20%), Positives = 173/359 (48%), Gaps = 47/359 (13%)
Query: 103 QESREEIPGGEARTDPPDGQQDSECNRNKEKTLGKEVLLLMQALNTLSTPEEKLAALCKK 162
QE E+I E + +Q+ + R +E KE + Q + EEK+ ++
Sbjct: 317 QEQEEKIREQEEKIR----EQEEKMRRQEEMMWEKEEKMRRQE-EMMWEKEEKMR---RQ 368
Query: 163 YADLLEESRSVQKQMKILQKKQAQI--VKEKVHLQSEHSKAILARSKLESLCRELQRHNK 220
+ E+ +++Q +++ +K+ +I ++EK+H Q + + R + E + + +R +
Sbjct: 369 EEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQ 428
Query: 221 TLKEENMQQA-REEEERRKEATAHFQITLDEIQAQLEQHDIHNAKLRQENIELGEKLKKL 279
K ++ RE+EE+ +E ++I EQ I + RQE E+ + +K+
Sbjct: 429 EAKMWRQEEKIREQEEKIREQEKKMWRQEEKIH---EQEKIREEEKRQEQEEMWRQEEKI 485
Query: 280 IEQYALREEHIDKVFKRKELQQQLVDAKLQQTTQLIKEADEKHQREREFLLKEATESRHK 339
EQ ++++++KE K+ + + I++ +EK R+ E + ++ + R +
Sbjct: 486 HEQ--------EEIWRQKE--------KMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQ 529
Query: 340 YEQMKQQEVQLKQQLSLYMDKFEEFQTTMAKSNELFTTFRQEMEKMTKKIKKLEKETIIW 399
E+M +QE ++++Q ++ ++ + E EK+ ++ K+ E+E +W
Sbjct: 530 EEKMWRQEEKIREQEEMWREEEK----------------MHEQEKIWEEEKRQEQEDKMW 573
Query: 400 RTKWENNNKALLQMAEEKTVRDKEYKALQIKLERLEKLCRALQTERNELNEKVEVLKEQ 458
R + + + +E+ +R++E K Q + E++ K ++ + ++ E+ E ++EQ
Sbjct: 574 RQEEKIREQEEKVWRQEEKIREQEEKR-QEQEEKMWKQEEKIREQEEKIQEQEEKIREQ 631
Score = 69.7 bits (169), Expect = 6e-12
Identities = 73/375 (19%), Positives = 169/375 (45%), Gaps = 44/375 (11%)
Query: 103 QESREEIPGGEARTDPPDGQQDSECNRNKEKTLGKEVLLLMQALNTLSTPEEKLAALCKK 162
+E E++ E + + +Q+ E R +EK +E + Q + EEK+ KK
Sbjct: 394 RELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE-EKIREQEEKIREQEKK 452
Query: 163 Y---ADLLEESRSVQKQMKILQKKQAQIVKEKVHLQSE--------HSKAILARSKLESL 211
+ + E ++++ K ++++ +EK+H Q E H + R + E +
Sbjct: 453 MWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKV 512
Query: 212 CRE---LQRHNKTLKEENMQQAREEEERRK-------EATAHFQITLDEIQAQLEQHDI- 260
R+ ++ + ++E+ + R+EE+ R+ E H Q + E + + EQ D
Sbjct: 513 WRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKM 572
Query: 261 --HNAKLRQENIELGEKLKKLIEQYALREEHIDKVFKRKELQQQLVDAKLQQTTQLIKEA 318
K+R++ ++ + +K+ EQ R+E +K++K++E I+E
Sbjct: 573 WRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEK---------------IREQ 617
Query: 319 DEKHQREREFLLKEATESRHKYEQMKQQEVQLKQQLSLYMDKFEEFQTTMAKSNELFTTF 378
+EK Q + E + ++ + R + E ++QE ++ +Q +K E + M + E
Sbjct: 618 EEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQ----EEKMCEQEEKMQEQEETMWRQ 673
Query: 379 RQEMEKMTKKIKKLEKETIIWRTKWENNNKALLQMAEEKTVRDKEYKALQIKLERLEKLC 438
+++ + KKI++ E++ + + + + E+ ++++ + + K+ R E+
Sbjct: 674 EEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKM 733
Query: 439 RALQTERNELNEKVE 453
+ + EK++
Sbjct: 734 WEQEVRLRQQEEKMQ 748
Score = 68.6 bits (166), Expect = 1e-11
Identities = 60/344 (17%), Positives = 173/344 (50%), Gaps = 15/344 (4%)
Query: 122 QQDSECNRNKEKTLGKEVLLLMQALNTLSTPEEKL--AALCKKYADLLEESRSVQKQMKI 179
++ E KE+ + ++ ++ + + EEK+ ++ + +E +++Q K
Sbjct: 366 RRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEK- 424
Query: 180 LQKKQAQIVKEKVHLQSEHSKAILARSKLESLCRELQRHNKTLKEENMQQAREEEERRKE 239
Q+++A++ +++ ++ + K K+ ++ K +EE Q+ +EE R+E
Sbjct: 425 RQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQE--QEEMWRQE 482
Query: 240 ATAHFQITLDEIQAQLEQHDIHNAKLRQENIELGEKLKKLIEQYALREEHIDKVFKRKEL 299
H Q +EI Q E+ K+R++ ++ + +K+ EQ E +K+++++E
Sbjct: 483 EKIHEQ---EEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEK 539
Query: 300 ---QQQL--VDAKLQQTTQLIKEADEKHQREREFLLKEATESRHKYEQMKQQEVQLKQQL 354
Q+++ + K+ + ++ +E EK Q + + + ++ + R + E++ +QE ++++Q
Sbjct: 540 IREQEEMWREEEKMHEQEKIWEE--EKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQE 597
Query: 355 SLYMDKFEEFQTTMAKSNELFTTFRQEMEKMTKKIKKLEKETIIWRTKWENNNKALLQMA 414
++ E+ K E +++ EK+ ++ +K+ ++ + + + E + +M
Sbjct: 598 EKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMC 657
Query: 415 EEKTVRDKEYKALQIKLERLEKLCRALQTERNELNEKVEVLKEQ 458
E++ ++ + + + E++ + + ++ + ++ E+ E+++EQ
Sbjct: 658 EQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQ 701
Score = 65.5 bits (158), Expect = 1e-10
Identities = 66/342 (19%), Positives = 163/342 (47%), Gaps = 32/342 (9%)
Query: 128 NRNKEKTLGKEVLLLMQALNTLSTPEEKLAALCKKYADLLEESRSVQKQMKILQKKQAQI 187
N+ +E+ + ++ + + + EEK+ +K + E+ +++Q +++ +K+ ++
Sbjct: 295 NQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEK---IREQEEKMRRQEEMMWEKEEKM 351
Query: 188 VKEKVHLQSEHSKAILARSKLESLCRELQRHNKTLKEENMQQAREEEERRKEATAHFQIT 247
+++ + + K R + E + ++ K ++E M +EE+ R E H Q
Sbjct: 352 RRQEEMMWEKEEKM---RRQEEMMW---EKEEKMRRQEEMMWEKEEKIRELEEKMHEQEK 405
Query: 248 LDEIQAQLEQHDIHNAKLRQENIELGEKLKKLIEQYALREEHIDKVFKRKELQQQLVDAK 307
+ E + + ++ + K+R++ ++ K ++ +RE+ ++ + +E + + K
Sbjct: 406 IREQEEKRQEEE----KIREQEKRQEQEAKMWRQEEKIREQ--EEKIREQEKKMWRQEEK 459
Query: 308 LQQTTQLIKEADEKHQREREFLLKEATESRHKYEQMKQQEVQLKQQLSLYMDKFEEFQTT 367
+ + ++ +E EK Q + E +E E H+ E++ +Q+ ++ +Q + E+
Sbjct: 460 IHEQEKIREE--EKRQEQEEMWRQE--EKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQ 515
Query: 368 MAKSNELFTTFRQEMEKMTKKIKKLEKETIIWRTK---------WENNNKALLQMAEEKT 418
K E R++ EKM ++ +K+ ++ +WR + WE + Q E+K
Sbjct: 516 EEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKR---QEQEDKM 572
Query: 419 VRDKE-YKALQIKLERLEKLCRALQTERNELNEKVEVLKEQV 459
R +E + + K+ R E+ R + +R E EK+ +E++
Sbjct: 573 WRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKI 614
Score = 60.5 bits (145), Expect = 4e-09
Identities = 84/405 (20%), Positives = 177/405 (43%), Gaps = 67/405 (16%)
Query: 104 ESREEIPGGEARTDPPDGQQDSECNRNKEKTLGKEVLLLMQALNTLSTPEEKLAALCKKY 163
E++E++ +T+P G S+ + K +N + PE + C
Sbjct: 62 EAKEQLTDHHPQTNPSVGTAASDTKKKK--------------INNGTNPETTTSGGCHSP 107
Query: 164 ADLLEESRSVQKQMKILQKKQAQI------VKEKVHLQSEHSKAILARSKLESLCREL-- 215
D E+ S Q Q + ++ +AQ+ +K LQ + A +LE R+L
Sbjct: 108 ED--EQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLIS 165
Query: 216 QRHNKTLKEENMQQAREEEERRKEATAHFQITL----DEIQAQLEQHDIHNAKLRQENIE 271
+ H+ ++QA +K+ + L D + +L ++ I + +L+++N +
Sbjct: 166 RLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAK 225
Query: 272 LGEKLKKLIE----QYALREEHIDKVFKRKEL---QQQL-------------VDAKLQ-- 309
L EKL+ L+E + L + + + +R +L QQQL V AKLQ
Sbjct: 226 LQEKLQ-LVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQ 284
Query: 310 ------------QTTQLIKEADEKHQREREFLLKEATESRHKYEQMKQQEVQLKQQLSLY 357
Q + + +EK Q E + ++ + R + E++++QE ++++Q +
Sbjct: 285 VEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMM 344
Query: 358 MDKFEEFQTTMAKSNELFTTFRQEMEKMTKKIKKLEKETIIWRTKWENNNKALLQMAEEK 417
+K E+ + E R++ E M +K +K+ ++ + K E + +M E++
Sbjct: 345 WEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQE 404
Query: 418 TVRDKEYKALQ----IKLERLEKLCRALQTERNELNEKVEVLKEQ 458
+R++E K + + E+ ++ + + ++ E+ E ++EQ
Sbjct: 405 KIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQ 449
Score = 48.9 bits (115), Expect = 1e-05
Identities = 33/183 (18%), Positives = 91/183 (49%), Gaps = 14/183 (7%)
Query: 169 ESRSVQKQMKILQKKQAQIVKEKVHLQSEHSKAILARSKLESLCRELQRHNKTLKE---- 224
+ +++Q + + +++ +I +++ Q + K K+ ++Q + ++E
Sbjct: 575 QEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEK 634
Query: 225 --ENMQQAREEEERRKEATAHFQITLDEIQAQLEQHDIHNAKLRQENIELGEKLKKLIEQ 282
E + +E+EE+ E +++Q Q E K+R++ ++ E+ +K+ EQ
Sbjct: 635 IREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQ 694
Query: 283 YALREEHIDKVFKRKELQQQLVDAKLQQTTQLIKEADEKHQREREFLLKEATESRHKYEQ 342
+ +E +K+++++E K+ + + ++E +EK +R+ E + ++ R + E+
Sbjct: 695 EEMMQEQEEKMWEQEE--------KMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEK 746
Query: 343 MKQ 345
M++
Sbjct: 747 MQE 749
Score = 34.3 bits (77), Expect = 0.29
Identities = 41/193 (21%), Positives = 86/193 (44%), Gaps = 10/193 (5%)
Query: 103 QESREEIPGGEARTDPPDGQQDSECNRNKEKTLGKEVLLLMQALNTLSTPEEKLAALCKK 162
+E R+E R + +Q+ + R +EK +E Q + EEK+ +K
Sbjct: 562 EEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQE-EKMWKQEEKIREQEEK 620
Query: 163 YADLLEESRSVQKQMKILQKKQAQIVKEKVHLQSEHSKAILARSKLESLCRELQRHNKTL 222
+ E+ R +++++ Q++ Q +EK+ Q E K K++ + R + +
Sbjct: 621 IQEQEEKIREQEEKIRE-QEEMTQEQEEKMGEQEE--KMCEQEEKMQEQEETMWRQEEKI 677
Query: 223 KE------ENMQQAREEEERRKEATAHFQITLDEIQAQLEQHDIHNAKLRQENIELGEKL 276
+E E ++ RE+EE +E +++ Q E+ K+R++ ++ E+
Sbjct: 678 REQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQE 737
Query: 277 KKLIEQYALREEH 289
+L +Q +EH
Sbjct: 738 VRLRQQEEKMQEH 750
>gi|237858621 polyamine modulated factor 1 binding protein 1 isoform
b [Homo sapiens]
Length = 882
Score = 72.0 bits (175), Expect = 1e-12
Identities = 62/310 (20%), Positives = 148/310 (47%), Gaps = 24/310 (7%)
Query: 129 RNKEKTLGKEVLLLMQALNTLSTPEEKLAAL-CKKYADLLEESRSVQKQMKILQKKQAQI 187
R +KT+ ++ + + L+ + + ++ CK DL Q+ K+L+ K+ Q+
Sbjct: 426 RQLQKTVAEQDMKMNDMLDRIKHQHREQGSIKCKLEEDL-------QEATKLLEDKREQL 478
Query: 188 VKEKVHLQSEHSKAILARSKLESLCRELQRHNKTLKEENMQQAREEEERRKEATAHFQIT 247
K K EH K L +LE+L +E ++ +KTLKE + R+ EE + A Q
Sbjct: 479 KKSK-----EHEK--LMEGELEALRQEFKKKDKTLKENS----RKLEEENENLRAELQCC 527
Query: 248 LDEIQAQLEQHDIHNAKLRQENIELGEKLKKLIEQYALREEHI--DKVFKRKELQQQLVD 305
++++ L +++ ++ N E+ + + L+ A ++ + +K + + + ++ D
Sbjct: 528 STQLESSLNKYNTSQQVIQDLNKEIALQKESLMSLQAQLDKALQKEKHYLQTTITKEAYD 587
Query: 306 AKLQQTTQLIKEADEKHQREREFLLKEATESRHKYEQMKQQEVQLKQQLSLYMDKFEEFQ 365
A L + + ++ + + + E + Q ++++ QL++++ Y ++ ++
Sbjct: 588 A-LSRKSAACQDDLTQALEKLNHVTSETKSLQQSLTQTQEKKAQLEEEIIAYEERMKKLN 646
Query: 366 TTMAKSNELFTTFRQEMEKMTKKIKKLEKETIIWRTKWENNNKALLQMAEEKTVRDKEYK 425
T + K E+ KK++++ + + W+ + +N+ K L A+E+ +R+ + +
Sbjct: 647 TELRKLRGFHQESELEVHAFDKKLEEMSCQVLQWQKQHQNDLKML--AAKEEQLREFQEE 704
Query: 426 ALQIKLERLE 435
+K LE
Sbjct: 705 MAALKENLLE 714
Score = 58.9 bits (141), Expect = 1e-08
Identities = 91/411 (22%), Positives = 179/411 (43%), Gaps = 41/411 (9%)
Query: 129 RNKEKTLGKEVLLLMQALNTLSTPEEKLAALCKKYADLLEESRSVQKQMKILQKKQAQIV 188
RNK VL +AL L A + EE ++K +K LQ+++
Sbjct: 115 RNKLACSNALVLEREKALIKLQADFASCTATHRYPPSSSEECEDIKKILKHLQEQKDS-- 172
Query: 189 KEKVHLQSEHSKAILARSKLESLCRELQRHNKTLK--EENMQQAREEE----ERRKEATA 242
+ +H++ + R +LE++ + + K + E ++ REE ER+ +
Sbjct: 173 -QCLHVEEYQNLVKDLRVELEAVSEQKRNIMKDMMKLELDLHGLREETSAHIERKDKDIT 231
Query: 243 HFQITLDEIQAQLEQHD---IHNAKLRQENIELGEKLKKLIEQYALREEHIDKVFKRKEL 299
Q L E+Q + + + K QE E+ ++L+K + Q + K KEL
Sbjct: 232 ILQCRLQELQLEFTETQKLTLKKDKFLQEKDEMLQELEKKLTQV-----QNSLLKKEKEL 286
Query: 300 Q-QQLVDAKLQQTTQLIKEADEKHQREREFLLKEATESRHKYEQMKQQE-------VQLK 351
+ QQ + +L+ T + K+ D+ + E + L E + ++ E+ KQQE Q K
Sbjct: 287 EKQQCMATELEMTVKEAKQ-DKSKEAECKALQAEVQKLKNSLEEAKQQERLAAQQAAQCK 345
Query: 352 QQLSLYMDKFEEFQTTMAKSNELFTTFRQEMEKMTKKIKKLEKETIIWRTKWENNNKALL 411
++ +L E+ Q + K L ++++ ++++ L+KE+ + + +N K +
Sbjct: 346 EEAALAGCHLEDTQRKLQKGLLLDKQKADTIQELQRELQMLQKESSMAEKEQTSNRKRVE 405
Query: 412 QMAEEKTVRDKEYKALQIKLERLEKLCRALQ----TERNELNEKVEVLKEQVSIKAAIKA 467
+++ E + +AL+ KLE +K R LQ + ++N+ ++ +K Q + +IK
Sbjct: 406 ELSLELS------EALR-KLENSDKEKRQLQKTVAEQDMKMNDMLDRIKHQHREQGSIKC 458
Query: 468 ANRDLATPVMQPCTALDSHKELNTSSKRALGAHLEAEPKSQRSAVQKPPST 518
+ +Q T L K + +E E ++ R +K T
Sbjct: 459 KLEE----DLQEATKLLEDKREQLKKSKEHEKLMEGELEALRQEFKKKDKT 505
Score = 54.7 bits (130), Expect = 2e-07
Identities = 91/385 (23%), Positives = 165/385 (42%), Gaps = 52/385 (13%)
Query: 128 NRNKEKTLGKEVLLLMQALNTLSTPEEKLAALCKKYADLLEESRSVQKQMKILQKKQAQI 187
N ++ L +E L L A + +++ E L KY L ++ Q+K+LQ + I
Sbjct: 7 NTGEKLHLAQEQLAL--AGDKIASLERSLNLYRDKYQSSLSNIELLECQVKMLQGELGGI 64
Query: 188 VKEKVHLQSEHSKAILARSKLESLCRELQRHNKTLKEENMQQAREE---EERRKEATAHF 244
+ ++ + +HSK + S + +E Q K L E + ++++ +E R +
Sbjct: 65 MGQEPENKGDHSKVRIYTS--PCMIQEHQETQKRLSEVWQKVSQQDDLIQELRNKLACSN 122
Query: 245 QITLDEIQAQLE-QHDIHNA----KLRQENIELGEKLKKLIEQYALREEHIDKVFKRKEL 299
+ L+ +A ++ Q D + + + E E +KK+++ L+E+ + +E
Sbjct: 123 ALVLEREKALIKLQADFASCTATHRYPPSSSEECEDIKKILKH--LQEQKDSQCLHVEEY 180
Query: 300 QQQLVDAKL------QQTTQLIK-----EADEKHQREREFLLKEATESRHKYEQMKQQEV 348
Q + D ++ +Q ++K E D RE E + Q + QE+
Sbjct: 181 QNLVKDLRVELEAVSEQKRNIMKDMMKLELDLHGLREETSAHIERKDKDITILQCRLQEL 240
Query: 349 QLK----QQLSLYMDKFEEFQTTMAKSNELFTTFRQEMEKMTKKIKKLEKETIIWRTKWE 404
QL+ Q+L+L DKF + + M + EL Q + KK K+LEK+
Sbjct: 241 QLEFTETQKLTLKKDKFLQEKDEMLQ--ELEKKLTQVQNSLLKKEKELEKQQC------- 291
Query: 405 NNNKALLQMAEEKTVRDKEYKALQIKLERLEKLCRALQTERNELNEKVEVLKEQVSIKAA 464
MA E + KE K + K E C+ALQ E +L +E K+Q + A
Sbjct: 292 --------MATELEMTVKEAKQDKSK----EAECKALQAEVQKLKNSLEEAKQQERLAAQ 339
Query: 465 IKAANRDLATPVMQPCTALDSHKEL 489
A ++ A + C D+ ++L
Sbjct: 340 QAAQCKEEA--ALAGCHLEDTQRKL 362
>gi|237858619 polyamine modulated factor 1 binding protein 1 isoform
a [Homo sapiens]
Length = 1007
Score = 72.0 bits (175), Expect = 1e-12
Identities = 62/310 (20%), Positives = 148/310 (47%), Gaps = 24/310 (7%)
Query: 129 RNKEKTLGKEVLLLMQALNTLSTPEEKLAAL-CKKYADLLEESRSVQKQMKILQKKQAQI 187
R +KT+ ++ + + L+ + + ++ CK DL Q+ K+L+ K+ Q+
Sbjct: 571 RQLQKTVAEQDMKMNDMLDRIKHQHREQGSIKCKLEEDL-------QEATKLLEDKREQL 623
Query: 188 VKEKVHLQSEHSKAILARSKLESLCRELQRHNKTLKEENMQQAREEEERRKEATAHFQIT 247
K K EH K L +LE+L +E ++ +KTLKE + R+ EE + A Q
Sbjct: 624 KKSK-----EHEK--LMEGELEALRQEFKKKDKTLKENS----RKLEEENENLRAELQCC 672
Query: 248 LDEIQAQLEQHDIHNAKLRQENIELGEKLKKLIEQYALREEHI--DKVFKRKELQQQLVD 305
++++ L +++ ++ N E+ + + L+ A ++ + +K + + + ++ D
Sbjct: 673 STQLESSLNKYNTSQQVIQDLNKEIALQKESLMSLQAQLDKALQKEKHYLQTTITKEAYD 732
Query: 306 AKLQQTTQLIKEADEKHQREREFLLKEATESRHKYEQMKQQEVQLKQQLSLYMDKFEEFQ 365
A L + + ++ + + + E + Q ++++ QL++++ Y ++ ++
Sbjct: 733 A-LSRKSAACQDDLTQALEKLNHVTSETKSLQQSLTQTQEKKAQLEEEIIAYEERMKKLN 791
Query: 366 TTMAKSNELFTTFRQEMEKMTKKIKKLEKETIIWRTKWENNNKALLQMAEEKTVRDKEYK 425
T + K E+ KK++++ + + W+ + +N+ K L A+E+ +R+ + +
Sbjct: 792 TELRKLRGFHQESELEVHAFDKKLEEMSCQVLQWQKQHQNDLKML--AAKEEQLREFQEE 849
Query: 426 ALQIKLERLE 435
+K LE
Sbjct: 850 MAALKENLLE 859
Score = 58.9 bits (141), Expect = 1e-08
Identities = 91/411 (22%), Positives = 179/411 (43%), Gaps = 41/411 (9%)
Query: 129 RNKEKTLGKEVLLLMQALNTLSTPEEKLAALCKKYADLLEESRSVQKQMKILQKKQAQIV 188
RNK VL +AL L A + EE ++K +K LQ+++
Sbjct: 260 RNKLACSNALVLEREKALIKLQADFASCTATHRYPPSSSEECEDIKKILKHLQEQKDS-- 317
Query: 189 KEKVHLQSEHSKAILARSKLESLCRELQRHNKTLK--EENMQQAREEE----ERRKEATA 242
+ +H++ + R +LE++ + + K + E ++ REE ER+ +
Sbjct: 318 -QCLHVEEYQNLVKDLRVELEAVSEQKRNIMKDMMKLELDLHGLREETSAHIERKDKDIT 376
Query: 243 HFQITLDEIQAQLEQHD---IHNAKLRQENIELGEKLKKLIEQYALREEHIDKVFKRKEL 299
Q L E+Q + + + K QE E+ ++L+K + Q + K KEL
Sbjct: 377 ILQCRLQELQLEFTETQKLTLKKDKFLQEKDEMLQELEKKLTQV-----QNSLLKKEKEL 431
Query: 300 Q-QQLVDAKLQQTTQLIKEADEKHQREREFLLKEATESRHKYEQMKQQE-------VQLK 351
+ QQ + +L+ T + K+ D+ + E + L E + ++ E+ KQQE Q K
Sbjct: 432 EKQQCMATELEMTVKEAKQ-DKSKEAECKALQAEVQKLKNSLEEAKQQERLAAQQAAQCK 490
Query: 352 QQLSLYMDKFEEFQTTMAKSNELFTTFRQEMEKMTKKIKKLEKETIIWRTKWENNNKALL 411
++ +L E+ Q + K L ++++ ++++ L+KE+ + + +N K +
Sbjct: 491 EEAALAGCHLEDTQRKLQKGLLLDKQKADTIQELQRELQMLQKESSMAEKEQTSNRKRVE 550
Query: 412 QMAEEKTVRDKEYKALQIKLERLEKLCRALQ----TERNELNEKVEVLKEQVSIKAAIKA 467
+++ E + +AL+ KLE +K R LQ + ++N+ ++ +K Q + +IK
Sbjct: 551 ELSLELS------EALR-KLENSDKEKRQLQKTVAEQDMKMNDMLDRIKHQHREQGSIKC 603
Query: 468 ANRDLATPVMQPCTALDSHKELNTSSKRALGAHLEAEPKSQRSAVQKPPST 518
+ +Q T L K + +E E ++ R +K T
Sbjct: 604 KLEE----DLQEATKLLEDKREQLKKSKEHEKLMEGELEALRQEFKKKDKT 650
Score = 54.7 bits (130), Expect = 2e-07
Identities = 91/385 (23%), Positives = 165/385 (42%), Gaps = 52/385 (13%)
Query: 128 NRNKEKTLGKEVLLLMQALNTLSTPEEKLAALCKKYADLLEESRSVQKQMKILQKKQAQI 187
N ++ L +E L L A + +++ E L KY L ++ Q+K+LQ + I
Sbjct: 152 NTGEKLHLAQEQLAL--AGDKIASLERSLNLYRDKYQSSLSNIELLECQVKMLQGELGGI 209
Query: 188 VKEKVHLQSEHSKAILARSKLESLCRELQRHNKTLKEENMQQAREE---EERRKEATAHF 244
+ ++ + +HSK + S + +E Q K L E + ++++ +E R +
Sbjct: 210 MGQEPENKGDHSKVRIYTS--PCMIQEHQETQKRLSEVWQKVSQQDDLIQELRNKLACSN 267
Query: 245 QITLDEIQAQLE-QHDIHNA----KLRQENIELGEKLKKLIEQYALREEHIDKVFKRKEL 299
+ L+ +A ++ Q D + + + E E +KK+++ L+E+ + +E
Sbjct: 268 ALVLEREKALIKLQADFASCTATHRYPPSSSEECEDIKKILKH--LQEQKDSQCLHVEEY 325
Query: 300 QQQLVDAKL------QQTTQLIK-----EADEKHQREREFLLKEATESRHKYEQMKQQEV 348
Q + D ++ +Q ++K E D RE E + Q + QE+
Sbjct: 326 QNLVKDLRVELEAVSEQKRNIMKDMMKLELDLHGLREETSAHIERKDKDITILQCRLQEL 385
Query: 349 QLK----QQLSLYMDKFEEFQTTMAKSNELFTTFRQEMEKMTKKIKKLEKETIIWRTKWE 404
QL+ Q+L+L DKF + + M + EL Q + KK K+LEK+
Sbjct: 386 QLEFTETQKLTLKKDKFLQEKDEMLQ--ELEKKLTQVQNSLLKKEKELEKQQC------- 436
Query: 405 NNNKALLQMAEEKTVRDKEYKALQIKLERLEKLCRALQTERNELNEKVEVLKEQVSIKAA 464
MA E + KE K + K E C+ALQ E +L +E K+Q + A
Sbjct: 437 --------MATELEMTVKEAKQDKSK----EAECKALQAEVQKLKNSLEEAKQQERLAAQ 484
Query: 465 IKAANRDLATPVMQPCTALDSHKEL 489
A ++ A + C D+ ++L
Sbjct: 485 QAAQCKEEA--ALAGCHLEDTQRKL 507
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 71.6 bits (174), Expect = 2e-12
Identities = 85/360 (23%), Positives = 167/360 (46%), Gaps = 44/360 (12%)
Query: 149 LSTPEEKLAALCKKYADLLEESRSVQKQMKILQKK--QAQIVKEKVHLQSEHSKAILARS 206
+ E+K + +K + E+ S++ +++ L+++ ++ +E V L +E+SKA
Sbjct: 2128 IEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKA----- 2182
Query: 207 KLESLCRELQRHNKTLK--EENMQQAREEEERRKEATAHFQITLDEIQAQLEQHDIHNAK 264
++E+L +++ ++LK E ++ R E+E + Q L E+ L +
Sbjct: 2183 EVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEE 2242
Query: 265 LRQENIELGEKLKKLIE--QYALRE--EHIDKVFKRKELQ---QQLVDAKLQQTTQLIK- 316
Q I++ E+ K +E Q L+E E + + +E+ +Q +D +++ QL
Sbjct: 2243 KEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNS 2302
Query: 317 --------EADEKHQREREFLLKEATESRHKYEQMKQQEVQLKQQLSLYMDKFEEFQTTM 368
EADEK Q +L++ ES H + +K + L+++L + E
Sbjct: 2303 IEKLRARLEADEKKQL---CVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEA 2359
Query: 369 AKSNELFTTFRQEMEKMTKKIKKLEKETIIWRTKWENNNKALLQMAE------------E 416
S T + ++E MT+ ++ LE + + R++ EN L + E E
Sbjct: 2360 ENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISELEIINSSFE 2419
Query: 417 KTVRDKEYKALQIKLERLEKLCRALQTERNELNEKVEVLKEQVSIKAAIKAANRDLATPV 476
+++KE + +Q+K E+ LQT+ ELNE+V L + A KA ++L++ V
Sbjct: 2420 NILQEKEQEKVQMK-EKSSTAMEMLQTQLKELNERVAALHND---QEACKAKEQNLSSQV 2475
Score = 71.2 bits (173), Expect = 2e-12
Identities = 92/420 (21%), Positives = 192/420 (45%), Gaps = 36/420 (8%)
Query: 120 DGQQDSECNRNKEKTLGKEVLLLMQALNTLSTPEEKLAALCKKYADLLEESRSVQKQMKI 179
DG+Q E + L ++ Q ++ LS E + ++ +L + +++++++
Sbjct: 2512 DGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQV 2571
Query: 180 LQKKQAQIVKEKVHLQSEHSKAI--LARSKLESLCRELQRHNKTLKEENMQQ-----ARE 232
LQ K A + LQS + L +K++ + + + T KE +Q+ A++
Sbjct: 2572 LQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQK 2631
Query: 233 EEERRKEATAHFQITLDEIQAQLEQHDIHNAKLRQENIELGEKLKKLIEQYALREEHIDK 292
E ++E + E+Q LE+ +L++ +E E LKK ++ H D+
Sbjct: 2632 TAELQEELSGEKNRLAGELQLLLEEIKSSKDQLKELTLENSE-LKKSLDCM-----HKDQ 2685
Query: 293 VFKRKELQQQLVDAKLQQTTQLIKEADEKHQR-----EREFLLKEATESRHKYEQMKQQE 347
V K ++++++ + +L+ + EA++KHQ +++ ++ T R K ++
Sbjct: 2686 VEKEGKVREEIAEYQLR-----LHEAEKKHQALLLDTNKQYEVEIQTY-REKLTSKEECL 2739
Query: 348 VQLKQQLSLYMDKFEEFQTTMAKSNELFTTFRQEMEKMTKKIKKLEKETIIWRTKWENNN 407
K ++ L EE ++ + ++ ++ K + +L+KE + K +
Sbjct: 2740 SSQKLEIDLLKSSKEELNNSLKATTQILEELKKTKMDNLKYVNQLKKENERAQGKMKLLI 2799
Query: 408 KALLQMAEEKTVRDKEYKALQIKLERLEKLCRALQTERNELNEKVEVLKEQVSIKAAIKA 467
K+ Q+ EEK + KE LQ E+ +K + T+ +EL +++ LKE + K K
Sbjct: 2800 KSCKQLEEEKEILQKELSQLQAAQEK-QKTGTVMDTKVDELTTEIKELKETLEEKT--KE 2856
Query: 468 ANRDLATPVMQPCTALDSHKELNTSSK--RALGAHL---EAEPKSQRSAVQKPPSTGSAP 522
A+ L + C+ L SH++L + + AHL +++ S+ S + P G +P
Sbjct: 2857 ADEYLD----KYCSLLISHEKLEKAKEMLETQVAHLCSQQSKQDSRGSPLLGPVVPGPSP 2912
Score = 59.7 bits (143), Expect = 6e-09
Identities = 84/405 (20%), Positives = 170/405 (41%), Gaps = 59/405 (14%)
Query: 103 QESREEIPGGEARTDPPDGQQDSECNRNKEKTLG--KEVLLLMQALNTLSTPEEKLAALC 160
QE R +I E R + + + N+ +E L K + L++ L+ ++L
Sbjct: 288 QELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELIEKEKVLNKCRDELVRTT 347
Query: 161 KKYADLLEESRSVQKQMKILQKKQAQIVKEKVHLQSEHSKAILARSKLESLCRELQRHNK 220
+Y + ++++++K L + L + A AR LE +E + K
Sbjct: 348 AQYDQASTKYTALEQKLKKLTED----------LSCQRQNAESARCSLEQKIKEKE---K 394
Query: 221 TLKEENMQQAREEEERRKEATAHFQITLDEIQAQLEQHDIHNAKLRQENIELGEKLKKLI 280
+EE +Q R + +E E+Q H++ A+L + + ++L+ +
Sbjct: 395 EFQEELSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAEL-DKLTSVKQQLENNL 453
Query: 281 EQYALREEHIDKVFKRKELQQQLVDAKLQQTTQ---LIKEADEKHQREREFLLKEA---- 333
E++ + ++ F+ ++++ + +++ + L+K E+ RE L E
Sbjct: 454 EEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIK 513
Query: 334 ---TESRHKYEQMK----QQEVQLK--------QQLSLYMDKFEEFQTTMAK----SNEL 374
+S++ E+MK QE L+ Q+ SL ++K + + K S +L
Sbjct: 514 QCLNQSQNFAEEMKAKNTSQETMLRDLQEKINQQENSLTLEKLKLAVADLEKQRDCSQDL 573
Query: 375 FTTFRQEMEKMTKKIKKLEKETIIWRTKWENNNKALLQMAEEKTV--------------R 420
+E++ K+ K EKE+ + E K ++ EEKT+
Sbjct: 574 LKKREHHIEQLNDKLSKTEKESKALLSALELKKKEYEELKEEKTLFSCWKSENEKLLTQM 633
Query: 421 DKEYKALQIKLERLEKLCRALQTERNELNEKVEVL---KEQVSIK 462
+ E + LQ K+ LE + Q + +E NE+V L +E +S++
Sbjct: 634 ESEKENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRENLSVE 678
Score = 58.9 bits (141), Expect = 1e-08
Identities = 95/383 (24%), Positives = 165/383 (43%), Gaps = 77/383 (20%)
Query: 133 KTLGKEVLLLMQALNTLSTPEEKLAALCKKYADLLEESRSVQKQMKILQKKQAQIVKEKV 192
+TL +V L++ L +EKL +L K L ++ Q+ L K++ +VKE
Sbjct: 2017 QTLSSDVSELLKDKTHL---QEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKE-- 2071
Query: 193 HLQSEHSKAILARSKLESLCRELQRHNKTLKEENMQQAREEEERRKEATAHFQITLDEIQ 252
SE +A L+ S E L N+ +A E K F + L Q
Sbjct: 2072 ---SESLQARLSESDYEKL--------------NVSKALEAALVEK---GEFALRLSSTQ 2111
Query: 253 AQLEQHDIHNAKLRQENIELGEKLKKLIEQYALREEHIDKVFKRKELQQQLVDAKLQQTT 312
++ Q LR+ EKL+ IE ++ HI + K +E + + K++
Sbjct: 2112 EEVHQ-------LRRGI----EKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLE 2160
Query: 313 QLIKEADEKHQREREFLLKEATESRHKYEQMKQQEVQLKQQLSLYMDKFEEFQTTMAKSN 372
+ ++ ++E +E ++ +A S+ + E +K Q ++ + L ++
Sbjct: 2161 RELQMSEE----NQELVILDAENSKAEVETLKTQIEEMARSLKVF--------------- 2201
Query: 373 EL-FTTFRQEMEKMTKKIKKLEKETIIWRTKWENNNKALLQMAEEKTVRDKEYKALQIKL 431
EL T R E E +TK+I++ + + + K ++ K+LL+ +KE +QIK
Sbjct: 2202 ELDLVTLRSEKENLTKQIQEKQGQ-LSELDKLLSSFKSLLE--------EKEQAEIQIK- 2251
Query: 432 ERLEKLCRALQTERNELNEKVEVLKEQVSIKAAIKAANRDLATPVMQPCTALDSHKELNT 491
E + LQ + ELNE V L I +KA + L P+ + H+ N+
Sbjct: 2252 EESKTAVEMLQNQLKELNEAVAALCGDQEI---MKATEQSLDPPIE------EEHQLRNS 2302
Query: 492 SSKRALGAHLEAEPKSQRSAVQK 514
K L A LEA+ K Q +Q+
Sbjct: 2303 IEK--LRARLEADEKKQLCVLQQ 2323
Score = 56.6 bits (135), Expect = 5e-08
Identities = 74/334 (22%), Positives = 151/334 (45%), Gaps = 48/334 (14%)
Query: 168 EESRSVQKQMKILQKKQAQIVKEKVHLQSEHSKAILARSKLESLCRELQRHNKT-----L 222
E V+ ++ ++ ++A I E ++L+++ L + E LC E NK L
Sbjct: 1895 ERFLDVENELSRIRSEKASIEHEALYLEAD-----LEVVQTEKLCLEKDNENKQKVIVCL 1949
Query: 223 KEENMQQAREEEERR-------KEATAHFQIT--LDEIQAQLEQHD---IHNAKLRQENI 270
+EE E + R K+ TA Q++ + E +LE H +H ++ + +
Sbjct: 1950 EEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEV 2009
Query: 271 ELGEKLKKLIEQYALREEHIDKVFKRKELQQQLVDAKLQQTTQL-IKEADEKHQREREFL 329
+ +L + + + E DK +++LQ D++ T+ ++ + +E+E L
Sbjct: 2010 KEKTELLQTLSS-DVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELL 2068
Query: 330 LKEATESRHKYEQMKQQEVQLKQQLSLYMDKFEEFQTTMAKSNELFTTFRQEMEKMTKKI 389
+KE+ + + + +++ + + L + + EF ++ + E E+ ++ + I
Sbjct: 2069 VKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQE-------EVHQLRRGI 2121
Query: 390 KKLEKETIIWRTKWENNNKALLQMAEEKTVRDKEYKALQIKLERLEKLCRALQTERNEL- 448
+KL R + E + K L +AE+ R++E +L+ K+E LE+ + + E EL
Sbjct: 2122 EKL-------RVRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQ-MSEENQELV 2173
Query: 449 -------NEKVEVLKEQVSIKA-AIKAANRDLAT 474
+VE LK Q+ A ++K DL T
Sbjct: 2174 ILDAENSKAEVETLKTQIEEMARSLKVFELDLVT 2207
Score = 52.0 bits (123), Expect = 1e-06
Identities = 92/446 (20%), Positives = 192/446 (43%), Gaps = 84/446 (18%)
Query: 81 EEDEGSDFITENRNLVSPAYCTQESRE----EIPGGEARTDPPDGQQDS----------- 125
E+ EG++ EN+ L+ +++++ E+ E++ + +GQ +S
Sbjct: 58 EKTEGTNLKRENQRLMEICESLEKTKQKISHELQVKESQVNFQEGQLNSGKKQIEKLEQE 117
Query: 126 ------ECNRNKEKTLGKEVLLLMQALNTLSTPEE---------------KLAALCKKYA 164
E R+++ +V +LN +TP++ K L +KY
Sbjct: 118 LKRCKSELERSQQAAQSADV-----SLNPCNTPQKIFTTPLTPSQYYSGSKYEDLKEKYN 172
Query: 165 DLLEESRSVQKQMKILQKKQAQIVKEKVHLQSEHSKAILARSKLESLCRELQRHNKTLKE 224
+EE + ++ ++K LQ K+A + Q+ + +AR + S Q+ KT
Sbjct: 173 KEVEERKRLEAEVKALQAKKA----SQTLPQATMNHRDIARHQASSSVFSWQQ-EKTPSH 227
Query: 225 ENMQQAREEEERRKEATAHF----QITLDEIQAQLEQHDIHNA------------KLRQE 268
+ R RR + ++F ++T Q+ + D +++ +L+ +
Sbjct: 228 LSSNSQR-TPIRRDFSASYFSGEQEVTPSRSTLQIGKRDANSSFFDNSSSPHLLDQLKAQ 286
Query: 269 NIELGEKLKKL-IEQYALREEHIDKVFKRKELQQQLVDAKLQQTTQLIKEADEKHQRERE 327
N EL K+ +L + +E +V K +ELQ QL AK++ + E ++ + R+
Sbjct: 287 NQELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVE-----LIEKEKVLNKCRD 341
Query: 328 FLLK---EATESRHKYEQMKQQEVQLKQQLSLYMDKFEEFQTTM-AKSNELFTTFRQEME 383
L++ + ++ KY ++Q+ +L + LS E + ++ K E F++E+
Sbjct: 342 ELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEELS 401
Query: 384 KMTKKIKKLEKETIIWRTK------WENNNKALLQMAEEKTVRDKE-----YKALQIKLE 432
+ + + L++E I + + N +LQ +K K+ + + KL
Sbjct: 402 RQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLC 461
Query: 433 RLEKLCRALQTERNELNEKVEVLKEQ 458
R E+ +A Q + NEL +E +K++
Sbjct: 462 RAEQAFQASQIKENELRRSMEEMKKE 487
Score = 47.0 bits (110), Expect = 4e-05
Identities = 55/286 (19%), Positives = 121/286 (42%), Gaps = 31/286 (10%)
Query: 205 RSKLESLCRELQRHNKTLKEENMQQAREEEERRKEATAHFQITLDEIQAQLEQHDIHNAK 264
R+K+ L LQ H K +K Q + +E Q+ L++ + +L + + K
Sbjct: 291 RNKINELELRLQGHEKEMKG----QVNKFQE--------LQLQLEKAKVELIEKEKVLNK 338
Query: 265 LRQENIELGEKLKKLIEQYALREEHIDKVFKRKELQQQLVDAKLQQTTQLIKEADEKHQR 324
R E + + + +Y E+ + K+ + Q+Q ++ Q IKE +++ Q
Sbjct: 339 CRDELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQE 398
Query: 325 E-----REF--LLKEATESRHKYEQMKQQEVQLKQQLSLYMDK-----------FEEFQT 366
E R F L +E + + + Q QQ + L +DK EEF+
Sbjct: 399 ELSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQ 458
Query: 367 TMAKSNELFTTFRQEMEKMTKKIKKLEKETIIWRTKWENNNKALLQMAEEKTVRDKEYKA 426
+ ++ + F + + ++ + +++++KE + ++ E + + + E +
Sbjct: 459 KLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQ 518
Query: 427 LQIKLERLEKLCRALQTERNELNEKVEVLKEQVSIKAAIKAANRDL 472
Q E ++ + +T +L EK+ + ++++ +K A DL
Sbjct: 519 SQNFAEEMKAKNTSQETMLRDLQEKINQQENSLTLE-KLKLAVADL 563
Score = 47.0 bits (110), Expect = 4e-05
Identities = 74/370 (20%), Positives = 157/370 (42%), Gaps = 58/370 (15%)
Query: 155 KLAALCKKYADLLEESRSVQKQMKI-LQKKQAQIVKEKVHLQSEHSKAILARSKLESLCR 213
K +A+ + D LE S QKQM LQK+ ++V+ K ++ E+L +
Sbjct: 823 KNSAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIE-------------ENLMK 869
Query: 214 ELQRHNKTLKEENMQQAREEEERRKEATAHFQI---TLDEIQAQLEQHDIHNAKLRQENI 270
Q H + E + + ++ +E + +AH + TL ++ + ++ + N K+ E
Sbjct: 870 AEQMHQSFVAETSQRISKLQE----DTSAHQNVVAETLSALENKEKELQLLNDKVETEQA 925
Query: 271 ELGEKLKKLIEQYALREEHIDKVFKRKELQQQLVDAKLQQTTQLIKEADEKHQREREFLL 330
E+ ++LKK L++ L++ QL+ E ++E ++
Sbjct: 926 EI-QELKK---------------------SNHLLEDSLKE-LQLLSETLSLEKKEMSSII 962
Query: 331 KEATESRHKYEQMKQQEVQLKQ-QLSLYMDKFEEFQTTMAKSNELFTTFRQEMEKMTKKI 389
+ ++ + E++ Q+ LK+ SL +K + + +E F + E EK ++
Sbjct: 963 ---SLNKREIEELTQENGTLKEINASLNQEKM-----NLIQKSESFANYIDEREKSISEL 1014
Query: 390 K-KLEKETIIWRTKWENNNKALLQMAEEKTVRDKEYKALQIKLERLEKLCRALQTERNEL 448
+ ++E +I + E A ++++ ++ L+ L LC + E +L
Sbjct: 1015 SDQYKQEKLILLQRCEETGNAYEDLSQKYKAAQEKNSKLECLLNECTSLCENRKNELEQL 1074
Query: 449 NEKVEVLKEQVSIKAAI-KAANRDLATPVMQPCTALDSHKELNTSSKRALGAHLEAE--- 504
E ++ K A + N++L + AL S N ++ ++ L+ E
Sbjct: 1075 KEAFAKEHQEFLTKLAFAEERNQNLMLELETVQQALRSEMTDNQNNSKSEAGGLKQEIMT 1134
Query: 505 PKSQRSAVQK 514
K +++ +QK
Sbjct: 1135 LKEEQNKMQK 1144
Score = 46.2 bits (108), Expect = 7e-05
Identities = 100/453 (22%), Positives = 182/453 (40%), Gaps = 79/453 (17%)
Query: 66 HQGSNCGGTSNKHSLEEDEGSDFITENRNLVSPAYCTQESRE---EIPGGEARTDPPDGQ 122
HQ + L+ED + ++N+V+ E++E ++ + T+ + Q
Sbjct: 874 HQSFVAETSQRISKLQEDTSA-----HQNVVAETLSALENKEKELQLLNDKVETEQAEIQ 928
Query: 123 QDSECNRNKEKTLGKEVLLLMQALNT--------LSTPEEKLAALCKKYADLLEESRSV- 173
+ + N E +L KE+ LL + L+ +S + ++ L ++ L E + S+
Sbjct: 929 ELKKSNHLLEDSL-KELQLLSETLSLEKKEMSSIISLNKREIEELTQENGTLKEINASLN 987
Query: 174 QKQMKILQKKQ--AQIVKEKVHLQSEHSKAILARSKLESLCRELQRHNKTLKEENMQQAR 231
Q++M ++QK + A + E+ SE S + KL L R + N +A
Sbjct: 988 QEKMNLIQKSESFANYIDEREKSISELSDQY-KQEKLILLQRCEETGNAYEDLSQKYKAA 1046
Query: 232 EEEERRKEATAHFQITLDEIQA-QLEQHDIHNAKLRQENI-------ELGEKLKKLIE-- 281
+E+ + E + +L E + +LEQ AK QE + E + L +E
Sbjct: 1047 QEKNSKLECLLNECTSLCENRKNELEQLKEAFAKEHQEFLTKLAFAEERNQNLMLELETV 1106
Query: 282 QYALREEHIDKVFKRKE----LQQQLVDAK-------------LQQTTQLIKEADEKHQR 324
Q ALR E D K L+Q+++ K LQ+ QL+K KH+
Sbjct: 1107 QQALRSEMTDNQNNSKSEAGGLKQEIMTLKEEQNKMQKEVNDLLQENEQLMKVMKTKHEC 1166
Query: 325 EREFLLKEATESRHKYEQMKQQEVQLKQQLSLYMDKF--EEFQTTMAKSNELFTTFRQEM 382
+ L E + K + ++ + K Q+ L + + + + + + + ++
Sbjct: 1167 QN--LESEPIRNSVKERESERNQCNFKPQMDLEVKEISLDSYNAQLVQLEAMLRNKELKL 1224
Query: 383 EKMTKKIKKLEKETIIWRTKWENNNKALLQMAEEKTVRDKEYKA---------------- 426
++ K+ + L+ E R E +N +Q E ++D E A
Sbjct: 1225 QESEKEKECLQHELQTIRGDLETSNLQDMQSQEISGLKDCEIDAEEKYISGPHELSTSQN 1284
Query: 427 --------LQI---KLERLEKLCRALQTERNEL 448
LQ KL LEK+C LQ E+ EL
Sbjct: 1285 DNAHLQCSLQTTMNKLNELEKICEILQAEKYEL 1317
Score = 44.3 bits (103), Expect = 3e-04
Identities = 57/266 (21%), Positives = 112/266 (42%), Gaps = 33/266 (12%)
Query: 122 QQDSECNRNKEKTLGKEVLL------LMQALNTLSTPEEKLAALCKKYADLLEESRSVQK 175
Q + K K +E +L + Q N+L+ + KLA ADL E+ R +
Sbjct: 518 QSQNFAEEMKAKNTSQETMLRDLQEKINQQENSLTLEKLKLAV-----ADL-EKQRDCSQ 571
Query: 176 QMKILQKKQAQIVKEKVHLQSEHSKAILARSKLESLCRELQRHNKTL----KEEN---MQ 228
+ ++ + + +K+ + SKA+L+ +L+ E + KTL K EN +
Sbjct: 572 DLLKKREHHIEQLNDKLSKTEKESKALLSALELKKKEYEELKEEKTLFSCWKSENEKLLT 631
Query: 229 QAREEEERRKEATAHFQITLDEIQAQLEQHDIHNAKLRQENIELGEKLKKLIEQYALREE 288
Q E+E + H + L Q + +++ L + L +++ L +
Sbjct: 632 QMESEKENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRENLSVEIRNLHNVLDSKSV 691
Query: 289 HIDKVFKRKELQQQLVDAKLQQTTQLIKEADEKHQREREFLLKEATESRHKYEQMKQQEV 348
++ Q+L +LQQ + +D+KHQ+E E + + ++ + E ++ +
Sbjct: 692 EVET--------QKLAYMELQQKAEF---SDQKHQKEIENMCLKTSQLTGQVEDLEHKLQ 740
Query: 349 QLKQQLSLYMDKFEEFQTTMAKSNEL 374
L ++ MDK +Q A+ L
Sbjct: 741 LLSNEI---MDKDRCYQDLHAEYESL 763
Score = 34.7 bits (78), Expect = 0.22
Identities = 32/142 (22%), Positives = 67/142 (47%), Gaps = 7/142 (4%)
Query: 380 QEMEKMTKKIKKLEKETIIWRTKWENNNKALLQMAEEKTVRDK-EYKALQIKLERLEKLC 438
QE+E K+KK +++ R ++ +A LQ ++K +K E L+ + +RL ++C
Sbjct: 21 QELEGQLDKLKKEKQQ----RQFQLDSLEAALQKQKQKVENEKTEGTNLKRENQRLMEIC 76
Query: 439 RALQTERNELNEKVEVLKEQVSIKAAIKAANRDLATPVMQPCTALDSHKELNTSSKRALG 498
+L+ + +++ +++V + QV+ + + + + Q S EL S + A
Sbjct: 77 ESLEKTKQKISHELQVKESQVNFQEGQLNSGKKQIEKLEQELKRCKS--ELERSQQAAQS 134
Query: 499 AHLEAEPKSQRSAVQKPPSTGS 520
A + P + + P T S
Sbjct: 135 ADVSLNPCNTPQKIFTTPLTPS 156
Score = 33.5 bits (75), Expect = 0.49
Identities = 76/386 (19%), Positives = 141/386 (36%), Gaps = 65/386 (16%)
Query: 167 LEESRSVQKQM---KILQKKQAQIVKEKVHLQSEHSKAILARSKLESLCRELQRHNKTLK 223
L+ES S + K +Q A++ ++ + LQSEH ++ S ELQ + +LK
Sbjct: 1384 LDESNSYEHLTLSDKEVQMHFAELQEKFLSLQSEHKILHDQHCQMSSKMSELQTYVDSLK 1443
Query: 224 EENMQQAREEEERRKEATAHFQITLDE---------------IQAQLEQHDIHNAKLRQE 268
EN+ + + + Q+ L+E + L + A L Q
Sbjct: 1444 AENLVLSTNLRNFQGDLVKEMQLGLEEGLVPSLSSSCVPDSSSLSSLGDSSFYRALLEQT 1503
Query: 269 NIELGEKLKKLIEQYALREEHIDKVFKRKELQQQLVDAKLQQTTQLIKEADEKHQREREF 328
L L + + +D+VF ++ L T + A K E E
Sbjct: 1504 GDM--SLLSNLEGAVSANQCSVDEVFCSSLQEENL-------TRKETPSAPAKGVEELES 1554
Query: 329 LLKEATESRHKYEQMKQQEVQLKQQLSLYMDKFEEFQTTMAKSNELFTTFRQEMEKMTKK 388
L + +S K E+ + + +K + + +E + +L ++ RQE++ + K+
Sbjct: 1555 LCEVYRQSLEKLEEKMESQGIMKNK------EIQELE-------QLLSSERQELDCLRKQ 1601
Query: 389 IKKLEKETIIWRTKWENNNKALLQMAEEKTVRDKEYKALQIKLERLEKLCRALQTERNEL 448
++ W+ K L+M + K+ + L ++LE + L L
Sbjct: 1602 YLSENEQ---WQQKL---TSVTLEMESKLAAEKKQTEQLSLELEVARLQLQGLDLSSRSL 1655
Query: 449 ------------NEKVEVLKEQVSIKAAIKAANRDLATPVMQPCTALDSHKELNTSSKRA 496
NE ++ KE S + R V Q C D+ ++LN ++
Sbjct: 1656 LGIDTEDAIQGRNESCDISKEHTS-----ETTERTPKHDVHQICDK-DAQQDLNLDIEKI 1709
Query: 497 LGAHLEAEPKSQRSAVQKPPSTGSAP 522
+P + S Q P + P
Sbjct: 1710 TETG-AVKPTGECSGEQSPDTNYEPP 1734
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 70.9 bits (172), Expect = 3e-12
Identities = 92/427 (21%), Positives = 184/427 (43%), Gaps = 60/427 (14%)
Query: 123 QDSECNRNKEKTLGKEVLLLMQALNTLSTPEEKLAALCKKYAD-----------LLEESR 171
Q+ E +E+ L +E L QA ++ + ++A K+A L +E+
Sbjct: 1597 QEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAE 1656
Query: 172 SVQKQMKILQKKQAQIVKEKVHLQSEHSKAILARSKLESLCRELQRHNKTLKEENMQQAR 231
+ ++ K L KK ++ +E+ L + K ++ L EL + + L + + A+
Sbjct: 1657 KLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQ 1716
Query: 232 EEEERRKEATAHFQITLDEIQAQLEQHDIHNAKLRQENIELGEKLKKLIEQYALREEHID 291
E L+E++ +E+ +L QE +L E+ KKL E+ EE +
Sbjct: 1717 E---------------LEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEE----EEAL- 1756
Query: 292 KVFKRKELQQQLVDAKLQQTTQLIKEADEKHQREREFLLKEATESRHKYEQMKQQEVQLK 351
++R++L ++ + KL Q +L+ + EK + +E + +E K EQ+ +++++L
Sbjct: 1757 -AWQREKLSEE--ETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLA 1813
Query: 352 QQLSLYMDKFEEF----------------QTTMAKSNELFTTFRQEMEKMTKKIKKLEKE 395
Q+ +++ EE + +A+ E ++ + +++ +K+
Sbjct: 1814 QKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQ 1873
Query: 396 TIIWRTKWENNNKALLQMAEEKTVRDKEYKALQIKLERLEKLCRALQTERNELNEKVEVL 455
+ + K NK L Q+ EEK ++KE + K E+L + + L + L +K E L
Sbjct: 1874 LVQVKNKLGMFNKILAQV-EEKLTQEKE--TVIKKKEKLAETEKKLVQVEDSLAKKQEKL 1930
Query: 456 KEQVSIKAAIKAANRDLATPVMQPCTALDSHKELNTSSKRALGAHLEAEPKSQRSAVQKP 515
++ +K A++ A + K LN KR AE K + ++
Sbjct: 1931 AQE-KMKLALEKAMVQGKKRLRGELDIAKEEKALNLEMKRL------AEEKMRLVEGKET 1983
Query: 516 PSTGSAP 522
S G P
Sbjct: 1984 LSKGETP 1990
Score = 70.1 bits (170), Expect = 5e-12
Identities = 72/277 (25%), Positives = 129/277 (46%), Gaps = 29/277 (10%)
Query: 181 QKKQAQIVKEKVHLQSEHSKAILARSKLESLCRELQRHNKTLKEENMQQAREE----EER 236
++K+ Q+ +E+ H+Q EH A + R + + + Q K +EE + A+EE +E
Sbjct: 1555 EEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEE-KLAQEERQLAQEE 1613
Query: 237 RKEATAHFQITLDEIQAQLEQHDIHNAKLRQENIELGEKLKKLIEQYALREEHIDKVFKR 296
RK A A+ +IT D+ ++ Q + A+ + + GEKL + E+ A KR
Sbjct: 1614 RKLAQAYVKITQDD--REMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQ---------KR 1662
Query: 297 KELQQQLVDAKLQQTTQLIKEADEKHQREREFLLKEATESRHKYEQMKQQEVQLKQQLSL 356
K KL + + + +EK ++ L + K E++ Q+E L Q
Sbjct: 1663 K---------KLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKE 1713
Query: 357 YMDKFEEFQTTMAKSNELFTTFRQEMEKMTKKIKKL--EKETIIWRTKWENNNKALLQMA 414
+ EE + M + + QE K+ ++ KKL E+E + W+ + + + L
Sbjct: 1714 LAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQE 1773
Query: 415 EEKTVRDKEYKALQIKLERLEKLCRALQTERNELNEK 451
EE +++KE K Q K E++ + L +R +L EK
Sbjct: 1774 EELLIQEKE-KLAQHK-EKMPEEEERLGRKREQLIEK 1808
Score = 56.6 bits (135), Expect = 5e-08
Identities = 84/380 (22%), Positives = 167/380 (43%), Gaps = 65/380 (17%)
Query: 132 EKTLGKEVLLLMQALNTLSTPEEKLAALCKKYADLLEESRSV-QKQMKILQKKQAQIVKE 190
++ L K L++ +LS KL + K L + R + Q+++K+ + K+A VKE
Sbjct: 2049 QRKLAKASRKLIKKRESLSKEPAKLNKILKALQKLTRDERKLTQEEIKMTKMKRALFVKE 2108
Query: 191 KVHLQSEHSKAILA-------RSKLESLCRELQRHNKTLKEENMQQAREEE----ERRKE 239
+ L E SK + RS+L ++L R + L + + +EE E K
Sbjct: 2109 R-RLSIEQSKLDIKEWDFSEKRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEESKL 2167
Query: 240 ATAHFQITLD-EIQAQLEQHDI----HNAKLRQENIELGEKLKKLIEQYALREEHIDKVF 294
A H ++ LD E + +E+ ++ +++ + G+K K E+++ + + ++
Sbjct: 2168 ARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPK---EKFSSQVDEVESEE 2224
Query: 295 KRKELQQQLVDAKLQQTTQLIKEADEKH-QRERE--------------------FLLKEA 333
E + L+D +Q + +E +E+ + ERE + KE
Sbjct: 2225 HFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEE 2284
Query: 334 TESRHKYEQMKQQEVQLKQQLSLYMDKFEEFQTTMAKSNELFTTFRQEMEKMTKKIKKLE 393
E + K ++ K++EVQ K+++ FEE + M++ + +E E+ ++++
Sbjct: 2285 EEKKKKKKEKKKEEVQEKEEV------FEEKEEIMSEEETESLSDEEEEEESCSLEEEVD 2338
Query: 394 KETIIWRTKWENNNKALLQMAEEKTVRDKEY-----------KALQIKLERLEKLCRALQ 442
+E I + + LQ K++R +E K I+L L+ + L
Sbjct: 2339 REKEILK----KEKQFKLQEQRRKSLRGRERVLSILRGVPHGKGRAIRLGVLKSPLKKLM 2394
Query: 443 TERNELNEK--VEVLKEQVS 460
+ E+ EK V V ++Q+S
Sbjct: 2395 STALEMKEKTPVPVPEKQIS 2414
Score = 54.7 bits (130), Expect = 2e-07
Identities = 72/359 (20%), Positives = 157/359 (43%), Gaps = 23/359 (6%)
Query: 122 QQDSECNRNKEKTLGKEVLLLMQALNTLSTPEEKLAA----LCKKYADLLEESRSVQKQM 177
Q++ + K+K +E L Q LS E KLA L ++ L + + ++
Sbjct: 1737 QEEGKLVEEKKKLAEEEEALAWQR-EKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEE 1795
Query: 178 KILQKKQAQIVKEKVHLQSEHSKAILARSKLESLCREL-QRHNKTLKEENMQQAREEEER 236
+ L +K+ Q++++K+ L + + I + +L L Q+ N +++N+ Q +E+ +
Sbjct: 1796 ERLGRKREQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQ 1855
Query: 237 RKEATAHFQITLDEIQAQLEQHDIHNAKLRQENIELGEKLKKLIEQYALREEHIDKVFKR 296
RKE + + L + QL Q + N KL N L + +KL ++ + V K+
Sbjct: 1856 RKENLLYNKERLTHSKKQLVQ--VKN-KLGMFNKILAQVEEKLTQEK-------ETVIKK 1905
Query: 297 KELQQQLVDAKLQQTTQLIKEADEKHQREREFLLKEATESRHKYEQMKQQEVQLKQQLSL 356
KE + +Q L K+ ++ Q + + L++A K + + + ++ L+L
Sbjct: 1906 KEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKEEKALNL 1965
Query: 357 YMDKFEEFQTTMAKSNELFTTFRQEMEKMTKKIKKLEKETIIWRTKWENNNKALLQMAEE 416
M + E + + + E T + E + +++ K + E ++ K K LL
Sbjct: 1966 EMKRLAEEKMRLVEGKE--TLSKGETPETSRQRKMTQVEQELFERKLSLEEKILLHEDRI 2023
Query: 417 KTVRDKEYKALQIKLERLEKLC-----RALQTERNELNEKVEVLKEQVSIKAAIKAANR 470
+ + E +++ R +++ + + R + ++ + KE + +KA +
Sbjct: 2024 LAMEESEIAKGKLEFTRGQRIFVQGQRKLAKASRKLIKKRESLSKEPAKLNKILKALQK 2082
Score = 51.6 bits (122), Expect = 2e-06
Identities = 94/430 (21%), Positives = 176/430 (40%), Gaps = 59/430 (13%)
Query: 134 TLGKEVLLLMQALNTLSTPEEKLAALCKKYA------DLLEESRSVQKQMKILQKKQAQI 187
T+GKE+ + +P++ A+ K+ ++ +E R + ++++ + + ++
Sbjct: 1382 TMGKEISKKEEKKTFQKSPKQGRKAVQKERKVGKIKREMTKEERDMSEEVEEMATLEEKV 1441
Query: 188 VKEKVHL-QSEHSKAIL----ARSKLESLCRELQRHNKTLKEENMQQAREEEERRKEATA 242
VK++ L E + + A + + + E ++ K KEE ++ +EEE+ +A
Sbjct: 1442 VKQEGKLVMIERTPSWQDWKKAWDEWKQVHGETRKSWKAWKEEWEKRLLQEEEKLHQAGE 1501
Query: 243 HFQITLDEIQAQLEQHDIHNAKLRQ--ENIELGEKLKKLI---EQYALREEHIDKVFKRK 297
+ +Q E + + +Q EN+ L K K+ E+ EE + + + K
Sbjct: 1502 KLSPEEEMLQ---EDKKLKWEEWKQVWENM-LSSKSKEQQYKDEEEVTLEEEVSREGEEK 1557
Query: 298 ELQQQLVDAKLQQTTQLIK------EADEKHQREREFLLKEATESRHKYEQMKQQEVQLK 351
E Q +Q+ + + A++K +E L +E + + Q+ Q+E +L
Sbjct: 1558 EQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLA 1617
Query: 352 Q----------QLSLYMDKFEEFQTTMAKSNELFTTFRQEMEKMTKKIKKLEKETIIWRT 401
Q +++ KF + + T+A+ E + QE EK+ +K KKL K+ W
Sbjct: 1618 QAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLS---QEAEKLAQKRKKLAKK---WEK 1671
Query: 402 KWENNNK-------------ALLQMAEEKTVR----DKEYKALQIKLERLEKLCRALQTE 444
K L Q EE R D + K L +LE LE L +
Sbjct: 1672 VAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELEELEWDMEELSWK 1731
Query: 445 RNELNEKVEVLKEQVSIKAAIKAANRDLATPVMQPCTALDSHKELNTSSKRALGAHLEAE 504
ELN++ L E+ A + A + + T L +EL K L H E
Sbjct: 1732 EEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKM 1791
Query: 505 PKSQRSAVQK 514
P+ + +K
Sbjct: 1792 PEEEERLGRK 1801
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 70.9 bits (172), Expect = 3e-12
Identities = 75/336 (22%), Positives = 154/336 (45%), Gaps = 34/336 (10%)
Query: 153 EEKLAALCKKYADLLEESRSVQKQMKILQKKQAQIVKEKVHLQSEHSKAILARSKLESLC 212
E+++A + +++ +E + + K L++K ++KEK LQ + + + E C
Sbjct: 849 EKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERC 908
Query: 213 RELQRHNKTLK---EENMQQAREEEERRKEATA---HFQITLDEIQAQLEQHDIHNAKLR 266
+L ++ L+ +E ++A EEEE E TA + E++ ++ ++ AK+
Sbjct: 909 EQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 968
Query: 267 QENIELGEKLKKLIEQYALREEHIDKVFKRKELQQQLVDAKLQQTTQLIKEADEKHQRER 326
+E K+K L E+ A +E I K+ K K+ LQ+T Q + + + +
Sbjct: 969 KEKHATENKVKNLTEEMAGLDETIAKLSKEKK--------ALQETHQQTLDDLQAEEDKV 1020
Query: 327 EFLLKEATESRHKYEQMKQQEVQLKQQLSLYMD---KFEEFQTTMAKSNELFTTFRQEME 383
L K T+ +Q+ E L+Q+ L MD + + + + E + +
Sbjct: 1021 NILTKAKTKLE---QQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQ 1077
Query: 384 KMTKKIKKLEKETIIWRTKWENNNKALLQMAEEKTVRDKEYKALQIKLERL------EKL 437
++ +K++K E E +K E+ +Q+ K+ K LQ ++E L E+
Sbjct: 1078 QLDEKLEKKEFEISNLISKIEDEQAVEIQL-------QKKIKELQARIEELGEEIEAERA 1130
Query: 438 CRA-LQTERNELNEKVEVLKEQVSIKAAIKAANRDL 472
RA + +R++L+ ++E + E++ +A +L
Sbjct: 1131 SRAKAEKQRSDLSRELEEISERLEEAGGATSAQVEL 1166
Score = 67.8 bits (164), Expect = 2e-11
Identities = 84/414 (20%), Positives = 171/414 (41%), Gaps = 47/414 (11%)
Query: 82 EDEGSDFITENRNLVSPAYCTQESREEIPGGEARTDPPDGQQDSECNRNKEKTLGKEVLL 141
E+ G + E + + E+ R + G ++ NK++ E
Sbjct: 1119 EELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKREA--EFQK 1176
Query: 142 LMQALNTLSTPEEKL-AALCKKYADLL----EESRSVQKQMKILQKKQAQIVKEKVHLQS 196
L + L + E + AAL KK+AD + E+ ++Q+ + L+K+++++ E L S
Sbjct: 1177 LRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSS 1236
Query: 197 EHSKAILARSKLESLCRELQRHNKTLKEENMQQAREEEERRKEATAHFQITLDEIQAQLE 256
A+ LE +CR L+ LK + +Q R + + A Q E QL+
Sbjct: 1237 NAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQ-RARLQTEAGEYSRQLD 1295
Query: 257 QHDIHNAKL---RQENIELGEKLKKLIEQYA-------------------LREEHIDKVF 294
+ D ++L +Q + + E+LK +E+ LRE++ ++
Sbjct: 1296 EKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQE 1355
Query: 295 KRKELQQQLVDA-------KLQQTTQLIKEADEKHQREREFLLKEATESRHKYEQMKQQE 347
+ ELQ+ L A + + T I+ +E + +++ L + E+ E + +
Sbjct: 1356 GKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKK-LAQRLQEAEEHVEAVNAKC 1414
Query: 348 VQLKQQLSLYMDKFEEFQTTMAKSNELFTTFRQEMEKMTKKIKKLEKETIIWRTKWENNN 407
L++ ++ E+ + +SN + KK + +K W+ K+E
Sbjct: 1415 ASLEKTKQRLQNEVEDLMLDVERSNAACAA-------LDKKQRNFDKVLSEWKQKYEETQ 1467
Query: 408 KAL-LQMAEEKTVRDKEYKALQIKLERLEKLCRALQTERNELNEKVEVLKEQVS 460
L E +++ + +K + E L++L L+ E L +++ L EQ++
Sbjct: 1468 AELEASQKESRSLSTELFKVKNVYEESLDQL-ETLRRENKNLQQEISDLTEQIA 1520
Score = 63.2 bits (152), Expect = 6e-10
Identities = 114/542 (21%), Positives = 222/542 (40%), Gaps = 94/542 (17%)
Query: 18 EATEAGRGGRRRSPRQKFEIGTMEEAGICGLGVKADMLCNSQSNDILQHQGSNCGGTSNK 77
E EA R R ++ +Q+ ++ E + ++ L+ G G TS +
Sbjct: 1123 EEIEAERASRAKAEKQRSDLSRELE----------------EISERLEEAG---GATSAQ 1163
Query: 78 HSLEEDEGSDFITENRNLVSPAYCTQESREEIPGGEARTDPPDGQQDSECNRNKEKTLGK 137
L + ++F R+L + + A + G+Q R K+K L K
Sbjct: 1164 VELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQK-LEK 1222
Query: 138 EVLLLMQALNTLSTPEEKLAALCKKYADLLEESRSVQKQMKILQKKQAQ-------IVKE 190
E L + LS+ E A+ K +L + RS++ Q+ L+ K+ + + +
Sbjct: 1223 EKSELKMETDDLSSNAE---AISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQ 1279
Query: 191 KVHLQSEHSKAILARSKLESLCRELQRHNK--TLKEENMQQAREEEERRKEATAHF---- 244
+ LQ+E + + ++L +L R + T + E ++ EEE + K A AH
Sbjct: 1280 RARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSS 1339
Query: 245 QITLDEIQAQLEQHDIHNAKLR----------------------QENIELGEKLKKLIEQ 282
+ D ++ Q E+ A+L+ Q EL E KKL ++
Sbjct: 1340 RHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQR 1399
Query: 283 YALREEHIDKVFKR--------KELQQQLVDAKLQ-QTTQLIKEADEKHQREREFLLKEA 333
EEH++ V + + LQ ++ D L + + A +K QR + +L
Sbjct: 1400 LQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVL--- 1456
Query: 334 TESRHKYEQMKQQ-EVQLKQQLSLYMDKFEEFQTTMAKSNELFTTFRQEMEKMTKKIKKL 392
+E + KYE+ + + E K+ SL + F + + +S + T R+E + + ++I L
Sbjct: 1457 SEWKQKYEETQAELEASQKESRSLSTELF-KVKNVYEESLDQLETLRRENKNLQQEISDL 1515
Query: 393 EKETIIWRTKWENNNKALLQMAE-EKTVRDKEYKALQIKLERLEKLCRALQTERNELNEK 451
+ Q+AE K + + E Q++ E+ E + E + +E+
Sbjct: 1516 TE-----------------QIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEE 1558
Query: 452 VEVLKEQVSIKAAIKAANRDLATPVMQPCTALDSHKELNTSSKRALGAHLEAEPKSQRSA 511
++L+ Q+ + +R +A + +D K +T + + L+AE +S+ A
Sbjct: 1559 GKILRIQLELNQVKSEVDRKIA----EKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDA 1614
Query: 512 VQ 513
++
Sbjct: 1615 LR 1616
Score = 53.5 bits (127), Expect = 5e-07
Identities = 77/408 (18%), Positives = 174/408 (42%), Gaps = 57/408 (13%)
Query: 122 QQDSECNRNKEKTLGKEVLLLM----QALNTLSTPEEKLAALCKKYADLLEESRSVQKQM 177
Q + E ++ + ++L E+ + ++L+ L T + L ++ +DL E+ KQ+
Sbjct: 1467 QAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQI 1526
Query: 178 KILQKKQAQIVKEKVHLQSEHSKAILARSKLESLCRELQRHNKTLKEENMQQAREEEERR 237
L+K + Q+ +EK +Q+ +A + E +Q +K E ++ E++E
Sbjct: 1527 HELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEI 1586
Query: 238 KEATAHFQITLDEIQAQLEQHDIHNAKLRQENIELGEKLKKLIEQYALREEHIDKVFKRK 297
+ + ++ +Q+ L+ A++R N L +V K+
Sbjct: 1587 DQLKRNHTRVVETMQSTLD------AEIRSRNDAL-------------------RVKKKM 1621
Query: 298 ELQQQLVDAKLQQTTQLIKEADEKHQREREFLLKEA----TESRHKYEQMKQQEVQLKQQ 353
E ++ +L +L E+ ++ R + +LKE ++ E +K+Q ++++
Sbjct: 1622 EGDLNEMEIQLNHANRLAAES-LRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERR 1680
Query: 354 LSLYMDKFEEFQTTMAKSNELFTTFRQEMEKMTKKIKKLEKET---IIWRTKWENNNKAL 410
+L + EE T+ ++ QE+ +++++ L + I + K EN+ L
Sbjct: 1681 ANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQL 1740
Query: 411 LQMAEE-------------KTVRDKEYKALQIKLER-----LEKLCRALQTERNELNEKV 452
EE K + D A ++K E+ LE++ + L+ +L ++
Sbjct: 1741 QSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRL 1800
Query: 453 EVLKEQVSIKAAIKAANRDLATPVMQPCTALDSHKELNTSSKRALGAH 500
+ EQ+++K K + L V + +++ ++ N + + L H
Sbjct: 1801 DE-AEQLALKGGKKQIQK-LEARVRELEGEVENEQKRNAEAVKGLRKH 1846
Score = 47.4 bits (111), Expect = 3e-05
Identities = 57/283 (20%), Positives = 127/283 (44%), Gaps = 41/283 (14%)
Query: 132 EKTLGKEVLLLMQALNTLSTPEEKLAALCKKYADLLEESRSVQKQMKILQKKQAQIVKEK 191
++ L +++ ++ + N L E+L A ++ E SR + +Q + ++ Q+
Sbjct: 1667 QEDLKEQLAIVERRANLLQAEIEELWATLEQ----TERSRKIAEQELLDASERVQL---- 1718
Query: 192 VHLQSEHSKAILARSKLESLCRELQRHNKTLKEENMQQAREEEERRKEATAHFQITLDEI 251
L ++++ I + KLE+ +LQ EE +Q++R EE+ K+A + +E+
Sbjct: 1719 --LHTQNTSLINTKKKLENDVSQLQSE----VEEVIQESRNAEEKAKKAITDAAMMAEEL 1772
Query: 252 QAQLEQHDIHNAKLRQENIELGEKLKKL------IEQYALR--EEHIDKVFKRKELQQQL 303
+ + + +A L + L + +K L EQ AL+ ++ I K+ R +
Sbjct: 1773 KKEQDT----SAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGE 1828
Query: 304 VDAKLQQTTQLIKEADEKHQREREFLLKEATESRH--------------KYEQMKQQEVQ 349
V+ + ++ + +K KH+R + L + E R K + K+Q +
Sbjct: 1829 VENEQKRNAEAVKGL-RKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEE 1887
Query: 350 LKQQLSLYMDKFEEFQTTMAKSNELFTTFRQEMEKMTKKIKKL 392
++Q + + KF + Q + ++ E ++ K+ K +++
Sbjct: 1888 AEEQSNANLSKFRKLQHELEEAEERADIAESQVNKLRVKSREV 1930
Score = 47.0 bits (110), Expect = 4e-05
Identities = 64/306 (20%), Positives = 127/306 (41%), Gaps = 44/306 (14%)
Query: 169 ESRSVQKQMKILQKKQAQIVKEKVHLQSEHSKAILARS-----KLESLCRELQRH--NKT 221
E RS +++ +K + + ++ +Q H+ + A S + + +E Q H +
Sbjct: 1607 EIRSRNDALRVKKKMEGDL--NEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDAL 1664
Query: 222 LKEENMQQAREEEERRKEATAHFQITLDEIQAQLEQHDIHNAKLRQENIELGEKLKKLIE 281
+E++++ ERR Q ++E+ A LEQ + QE ++ E+++
Sbjct: 1665 RGQEDLKEQLAIVERRANL---LQAEIEELWATLEQTERSRKIAEQELLDASERVQ---- 1717
Query: 282 QYALREEHIDKVFKRKELQQQL--VDAKLQQTTQLIKEADEKHQRE-------REFLLKE 332
L ++ + +K+L+ + + +++++ Q + A+EK ++ E L KE
Sbjct: 1718 --LLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKE 1775
Query: 333 ATESRHKYEQMKQQEVQLKQQLSLYMDKFEEFQTTMAKSNELFTTFRQEMEKMTKKIKKL 392
S H E+MK+ Q + L +D+ E+ K K+I+KL
Sbjct: 1776 QDTSAH-LERMKKNLEQTVKDLQHRLDEAEQLALKGGK----------------KQIQKL 1818
Query: 393 EKETIIWRTKWENNNKALLQMAEEKTVRDKEYKALQIKLERLEKLCRALQTERNELNEKV 452
E + EN K + + ++ K L + E K LQ ++L KV
Sbjct: 1819 EARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKV 1878
Query: 453 EVLKEQ 458
+ K Q
Sbjct: 1879 KSYKRQ 1884
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 70.5 bits (171), Expect = 4e-12
Identities = 80/328 (24%), Positives = 153/328 (46%), Gaps = 44/328 (13%)
Query: 131 KEKTLGKEVLLLMQALNTLSTPEEKLAALCKKYADLLEESRSVQKQMKILQKKQAQIVKE 190
+E T ++ L L NT++ E K KK A+L E+ R + + K + Q+ +
Sbjct: 162 EELTKERDALSLELYRNTITNEELK-----KKNAELQEKLRLAESE-----KSEIQLNVK 211
Query: 191 KVHLQSEHSKAILARSKLESLCRELQRHNKTLKEENMQQAREEEERRKEATAHFQITLDE 250
++ + E +K +L + + +L E+ R + L+E+ ++ R++EE+ + +
Sbjct: 212 ELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQE-KKIRKQEEKMWRQEERLREQEGK 270
Query: 251 IQAQLEQHDIHNAKLRQENIELGEKLKKLIEQYALREEHIDKVFKRKELQQQLVDAKLQQ 310
++ Q E+ +LR++ EL E+ K+L EQ LRE+ E Q Q + K+ +
Sbjct: 271 MREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQ---------EEQMQEQEEKMWE 321
Query: 311 TTQLIKEADEKHQREREFLLKEATESRHKYEQMKQQEVQLKQQLSLYMDKFEEFQTTMAK 370
+ ++E +EK R+ E ++ +QE Q+++Q D+ E +
Sbjct: 322 QEEKMREQEEKMWRQEE--------------RLWEQEKQMREQEQKMRDQEERMWEQDER 367
Query: 371 SNELFTTFRQEMEKMTKKIKKLEKETIIWRTKWENNNKALLQMAEEKTVRDKEYKALQIK 430
E R E EKM ++ +K+++E I + EE+T+R++E K + +
Sbjct: 368 LREKEERMR-EQEKMWEQEEKMQEEERI-------REREKKMREEEETMREQEEKMQKQE 419
Query: 431 LERLEKLCRALQTERNELNEKVEVLKEQ 458
E+ + Q +R L E+ E L EQ
Sbjct: 420 ENMWEQEEKEWQQQR--LPEQKEKLWEQ 445
Score = 66.2 bits (160), Expect = 7e-11
Identities = 74/359 (20%), Positives = 159/359 (44%), Gaps = 27/359 (7%)
Query: 122 QQDSECNRNKEKTLGKEVLLLMQALNTLSTPEEKLAALCKKYADLLEESRSVQKQM---K 178
+Q+ + + +EK +E L Q + EEK+ K+ + +E R +K++ K
Sbjct: 245 EQEKKIRKQEEKMWRQEERLREQE-GKMREQEEKMRRQEKRLREQEKELREQEKELREQK 303
Query: 179 ILQKKQAQIVKEKVHLQSEHSKAILARSKLESLCRELQRHNKTLKEENMQQAREEEERRK 238
L++++ Q+ +++ + + K K+ L K ++E+ Q+ R++EER
Sbjct: 304 KLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQE-QKMRDQEERMW 362
Query: 239 EATAHFQITLDEIQAQLEQHDIHNAKLRQENIELGEKLKKLIEQYALREEHIDKVFKR-- 296
E + + ++ Q + + +E I E+ KK+ E+ E +K+ K+
Sbjct: 363 EQDERLREKEERMREQEKMWEQEEKMQEEERIR--EREKKMREEEETMREQEEKMQKQEE 420
Query: 297 -------KELQQQLV---------DAKLQQTTQLIKEADEKHQREREFLLKEATESRHKY 340
KE QQQ + K+Q+ + I E +EK + + E +E + +
Sbjct: 421 NMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQE--KKMWRQ 478
Query: 341 EQMKQQEVQLKQQLSLYMDKFEEFQTTMAKSNELFTTFRQEMEKMTKKIKKLEKETIIWR 400
E+M++QE Q+ +Q D+ ++ + E R++ E+M ++ K ++E +
Sbjct: 479 EKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMRE 538
Query: 401 TKWENNNKALLQMAEEKTVRDKEYKALQIKLERLEKLCRALQTERNELNEKVEVLKEQV 459
K + EEK ++ + + K+ E++ R + + E EK+ +E++
Sbjct: 539 EKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKM 597
Score = 64.3 bits (155), Expect = 3e-10
Identities = 78/373 (20%), Positives = 169/373 (45%), Gaps = 58/373 (15%)
Query: 103 QESREEIPGGEARTDPPDGQQDSECNRNKEKTLGKEVLLLMQALNTLSTPEEKLAALCKK 162
+E E + E + + Q+ E R +EK + +E T+ EEK+ K+
Sbjct: 369 REKEERMREQEKMWEQEEKMQEEERIREREKKMREEE-------ETMREQEEKMQ---KQ 418
Query: 163 YADLLEESRSVQKQMKILQKKQAQIVKEKVHLQSE----HSKAILARSKLESLCRELQRH 218
++ E+ +Q ++ ++K+ +EK+ Q E + I + ++ +++ R
Sbjct: 419 EENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQ 478
Query: 219 NKTLKEENMQQAREEEERRKEATAHFQITLDEIQAQLEQHDIHNAKLRQENIELGEKLKK 278
K ++E+ +EE+ R +E Q D+ + EQ + +LR++ + E+ K
Sbjct: 479 EKMREQEDQMWEQEEKMRDQE-----QKMWDQEERMWEQDE----RLREKEERMREQKKM 529
Query: 279 LIEQYALREEHIDKVFKRKELQQQLVDAKLQQTTQLIKEADEKHQREREFLLKEATESRH 338
++ +REE K +E +++ D Q K +E+ RERE ++E
Sbjct: 530 WQQEEKMREEK-----KTQEQEKKTWD-------QEEKMREEERMREREKKMRE------ 571
Query: 339 KYEQMKQQEVQLKQQ---LSLYMDKFEEFQTTMAKSNELFTTFRQEMEKMTKKIKKLEKE 395
+ E M++QE ++++Q + +K E + M + E ++M + ++ K E+E
Sbjct: 572 EEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQE 631
Query: 396 TIIWRTK----------WENNNKALLQMAEEKTVRDKEYKALQIKLERLEKLCRALQTER 445
++W + WE K +E+ +R++E K +Q + E++ + +Q +
Sbjct: 632 EMMWEQEEKMQEQEEKMWEQEEK---MREQEEKMREQEEK-MQGQEEKMREQEEKMQGQE 687
Query: 446 NELNEKVEVLKEQ 458
++ E+ E ++ Q
Sbjct: 688 EKMREQEEKMRGQ 700
Score = 60.1 bits (144), Expect = 5e-09
Identities = 59/300 (19%), Positives = 144/300 (48%), Gaps = 16/300 (5%)
Query: 153 EEKLAALCKKYADLLE---ESRSVQKQMKILQKKQAQIVKEKVHLQSEHSKAILARSKLE 209
EEK+ +K D E + + + +Q K +++++ Q+ +++ ++ + K ++
Sbjct: 452 EEKIWEQEEKIRDQEEMWGQEKKMWRQEK-MREQEDQMWEQEEKMRDQEQKMWDQEERMW 510
Query: 210 SLCRELQRHNKTLKEEN---MQQAREEEERRKEATAHFQITLDEIQAQLEQHDIHNAKLR 266
L+ + ++E+ Q+ + EE++ + +E + E+ K+R
Sbjct: 511 EQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMR 570
Query: 267 QENIELGEKLKKLIEQYALREEHIDKVFKRKELQQQLVDAKLQQTTQL-IKEADEKHQRE 325
+E + E+ +K+ EQ E +K+++++E Q+ + +Q ++ +E ++K Q +
Sbjct: 571 EEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQ 630
Query: 326 REFLLKEATESRHKYEQMKQQEVQLKQQLSLYMDKFEEFQTTMAKSNELFTTFRQEMEKM 385
E + ++ + + + E+M +QE ++++Q ++ E+ Q K E + + EKM
Sbjct: 631 EEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKM 690
Query: 386 TKKIKKLE-KETIIW---RTKWENNNKALLQ---MAEEKTVRDKEYKALQIKLERLEKLC 438
++ +K+ +E +W W K Q +E+ +RD++ K +Q +L E+ C
Sbjct: 691 REQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEK-MQERLPEHEERC 749
>gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]
Length = 1417
Score = 70.5 bits (171), Expect = 4e-12
Identities = 78/362 (21%), Positives = 166/362 (45%), Gaps = 25/362 (6%)
Query: 167 LEESRSVQKQMKILQKKQAQIVKEKVHLQ-SEHSKAILARSKLESLCRELQRHNKTLKE- 224
L + + Q K +K+ VKE LQ S ++ A K E L ELQ + LK
Sbjct: 1020 LSQLDMILDQTKTELEKKTNAVKELEKLQHSTETELTEALQKREVLETELQNAHGELKST 1079
Query: 225 -ENMQQAREEEERRKEATAHFQITLDEIQAQLEQHDIHNAKLRQENIELGEKLKKL---I 280
+Q+ R+ ++ + + T+ ++ A+L + + +QE +E+ + LK+ +
Sbjct: 1080 LRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWEL 1139
Query: 281 EQYALREEHIDKVFK--RKELQQQLV--DAKLQQTTQLIKEADEKHQREREFLLKEATES 336
+Q A + H+D + R E++Q+++ + L+++ +KE +++ + + L +
Sbjct: 1140 KQRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQL 1199
Query: 337 RHKYEQMKQQE---VQLKQQLSLYMDKFEEFQTTMAKSNELFTTFRQEMEKMTKKIKKLE 393
R K M Q E QLK+++ + +E ++ M + + T K+ L
Sbjct: 1200 REKEFIMLQNEQEISQLKKEIERTQQRMKEMESVMKEQEQYIAT-------QYKEAIDLG 1252
Query: 394 KETIIWRTKWENNNKALLQMAEEKTVRDKEYKALQIKLERLEKLCRALQTERNELNEKVE 453
+E + R + +N++ L + ++ +E + L +LE +++L + N L E++
Sbjct: 1253 QELRLTREQVQNSHTELAEARHQQVQAQREIERLSSELEDMKQLSKEKDAHGNHLAEELG 1312
Query: 454 VLK-EQVSIKAAIKAANRDLATPVMQPCTALDSHKELNTSSKRALGAHLEAEPKSQRSAV 512
K + ++A ++A + L+ V +L + S + A + SQ+S+V
Sbjct: 1313 ASKVREAHLEARMQAEIKKLSAEV----ESLKEAYHMEMISHQENHAKWKISADSQKSSV 1368
Query: 513 QK 514
Q+
Sbjct: 1369 QQ 1370
Score = 64.3 bits (155), Expect = 3e-10
Identities = 94/428 (21%), Positives = 188/428 (43%), Gaps = 68/428 (15%)
Query: 149 LSTPEEKLAALCKKYADL-LEESRSVQKQMKILQ----KKQAQIVKEKVHLQSEHSKAIL 203
++T EK+ +K + LE+ + ++KQ++ L+ KK Q +++ + I
Sbjct: 741 INTEHEKICLAFEKAKKIHLEQHKEMEKQIERLEAQLEKKDQQFKEQEKTMSMLQQDIIC 800
Query: 204 ARSKLESLCRELQRHNKTLKEENMQ----------QAREEEERRKEATAHFQITLDEIQA 253
+ LESL R L +K+ENM+ Q EE + ++ + +I +E+
Sbjct: 801 KQHHLESLDRLLTESKGEMKKENMKKDEALKALQNQVSEETIKVRQLDSALEICKEELVL 860
Query: 254 QLEQHDIHNAKLRQENIELGEKLKKL-----IEQYALREEHIDKVFKRKELQQQ------ 302
L Q + + K ++ + E++ L I+ ++L+E V + LQQQ
Sbjct: 861 HLNQLEGNKEKFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQ 920
Query: 303 --LVDAKLQQT-TQLIKEA---DEKHQREREFL------LKEATESR-HKYEQMKQQEVQ 349
+ + +L+ T T+L K+ +++ Q++RE ++E ES H+ + +Q+ ++
Sbjct: 921 ETIRNGELEDTQTKLEKQVSKLEQELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIE 980
Query: 350 LK---QQLSLYMDKFEEFQTTMAKS------------------NELFTTFRQEMEKMTKK 388
L +Q+ + MD+++E + M K + + + E+EK T
Sbjct: 981 LTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNA 1040
Query: 389 IKKLEKETIIWRTKWENNNKALLQMAEEKTVRDKEYKALQIKLERLEKLCRALQTERNEL 448
+K+LEK + + +AL + +T + L+ L +L++L LQ + L
Sbjct: 1041 VKELEK---LQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSL 1097
Query: 449 NEKVEVLKEQVSIKAAIKAANRDLATPVMQPCTALDSHKELNTSSKR--ALGAHLEAEPK 506
EK +K+ + K D +++ AL KE N K+ A HL+ +
Sbjct: 1098 EEKYTTIKDLTAELRECKMEIEDKKQELLEMDQAL---KERNWELKQRAAQVTHLDMTIR 1154
Query: 507 SQRSAVQK 514
R +++
Sbjct: 1155 EHRGEMEQ 1162
Score = 52.4 bits (124), Expect = 1e-06
Identities = 84/382 (21%), Positives = 167/382 (43%), Gaps = 47/382 (12%)
Query: 131 KEKTLGKEVLLLMQALNTLSTPEEKLAALCKKYADLLEESRSVQKQMKI-LQKKQAQIVK 189
K + G + L +++ S E++ C E ++ V +++I L K+A+I K
Sbjct: 523 KRELFGFKSYLSKYQMSSFSNKEDRCIGCC-------EANKLVISELRIKLAIKEAEIQK 575
Query: 190 EKVHLQSEH-SKAILA------RSKLESLCRE---LQRHN--KTLKEENMQQARE--EEE 235
+L + S++++ SKL SL E L H +++K++N + E+E
Sbjct: 576 LHANLTANQLSQSLITCNDSQESSKLSSLETEPVKLGGHQVAESVKDQNQHTMNKQYEKE 635
Query: 236 RRKEATAHFQITLDEIQAQLEQHDIH-NAKLRQENIEL--GEKLKKLIEQYALREEHIDK 292
R++ T ++ IQ + E D+ N R +L E L+K L E K
Sbjct: 636 RQRLVTGIEELRTKLIQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSKLESEMTKK 695
Query: 293 VFKRKELQQQL---------VDAKLQQTTQLIKEADEK---------HQREREFLLKEAT 334
+ L++QL + AK + Q + E +EK + E+ L E
Sbjct: 696 CSQLLTLEKQLEEKIVAYSSIAAKNAELEQELMEKNEKIRSLETNINTEHEKICLAFEKA 755
Query: 335 ESRH--KYEQMKQQEVQLKQQLSLYMDKFEEFQTTMAKSNELFTTFRQEMEKMTKKIKKL 392
+ H ++++M++Q +L+ QL +F+E + TM+ + + +E + + + +
Sbjct: 756 KKIHLEQHKEMEKQIERLEAQLEKKDQQFKEQEKTMSMLQQDIICKQHHLESLDRLLTES 815
Query: 393 EKETIIWRTKWENNNKALLQMAEEKTVRDKEY-KALQIKLERLEKLCRALQTERNELNEK 451
+ E K + KAL E+T++ ++ AL+I E L L+ + + ++
Sbjct: 816 KGEMKKENMKKDEALKALQNQVSEETIKVRQLDSALEICKEELVLHLNQLEGNKEKFEKQ 875
Query: 452 VEVLKEQV-SIKAAIKAANRDL 472
++ E+V ++ +K N L
Sbjct: 876 LKKKSEEVYCLQKELKIKNHSL 897
Score = 43.9 bits (102), Expect = 4e-04
Identities = 86/405 (21%), Positives = 182/405 (44%), Gaps = 51/405 (12%)
Query: 133 KTLGKEVLLLMQALNTLSTPEEKLAALCKKYADLLEESRSVQKQMKILQKKQAQIV---K 189
K+L +++ L Q L T L + L +SR+ ++ Q++ A + +
Sbjct: 232 KSLREKLNKLRQQNACLVTQNHSLMTKFESIHFELTQSRAKVSMLESAQQQAASVPILEE 291
Query: 190 EKVHLQSEHSKAILARSKLESLCRELQRHNKTL--KEENMQQAREEEERRKEATAHFQIT 247
+ ++L++E S + E+ +L++ K + KE+++Q+++EE + K + T
Sbjct: 292 QIINLEAEVSAQDKVLREAEN---KLEQSQKMVIEKEQSLQESKEECIKLKVDL--LEQT 346
Query: 248 LDEIQAQLEQHD-IHNAK-----LRQENIELGEKLKKLIEQYALREEHIDKVFKR-KELQ 300
+A+ ++++ ++NA+ +Q ++ EKL+K+ + + E ++ K K LQ
Sbjct: 347 KQGKRAERQRNEALYNAEELSKAFQQYKKKVAEKLEKVQAEEEILERNLTNCEKENKRLQ 406
Query: 301 QQ--LVDAKLQQTTQLIKEADEKHQREREFL----------LKEATESRHKY----EQMK 344
++ L ++L+ + +++ E++ +E L + + TESR +++
Sbjct: 407 ERCGLYKSELEILKEKLRQLKEENNNGKEKLRIMAVKNSEVMAQLTESRQSILKLESELE 466
Query: 345 QQEVQLKQQLSLYMDKFEEFQTTMAKSNELFTTFRQEMEKMTKKIKKLEKETIIWRTKWE 404
++ L+ + SL M++ E + +A NE +QE+E +++ LEK K E
Sbjct: 467 NKDEILRDKFSL-MNENRELKVRVAAQNERLDLCQQEIESSRVELRSLEKIISQLPLKRE 525
Query: 405 -NNNKALLQMAEEKTVRDKEYKALQIKLERLEKLCRALQTERNELNEKVEVLKEQVSIKA 463
K+ L + + +KE +R C A + +EL K+ + + ++
Sbjct: 526 LFGFKSYLSKYQMSSFSNKE--------DRCIGCCEANKLVISELRIKLAIKEAEIQKLH 577
Query: 464 AIKAANRDLATPVMQPCTALDSHKELNTSSKRA----LGAHLEAE 504
A AN+ + + T DS + SS LG H AE
Sbjct: 578 ANLTANQLSQSLI----TCNDSQESSKLSSLETEPVKLGGHQVAE 618
Score = 32.0 bits (71), Expect = 1.4
Identities = 29/142 (20%), Positives = 61/142 (42%), Gaps = 21/142 (14%)
Query: 331 KEATESRHKYEQMKQQEVQLKQQLSLYMDKFE--EFQTTMAKSNELFTTFRQEMEKMTKK 388
+E R K +++QQ L Q M KFE F+ T +++ + + ++
Sbjct: 229 QEIKSLREKLNKLRQQNACLVTQNHSLMTKFESIHFELTQSRAK---VSMLESAQQQAAS 285
Query: 389 IKKLEKETIIWRTKWENNNKALLQMAEEKTVRDKEYKALQIKLERLEKLCRALQTERNEL 448
+ LE++ ++ + E + +DK + + KLE+ +K+ ++ E++
Sbjct: 286 VPILEEQ--------------IINLEAEVSAQDKVLREAENKLEQSQKM--VIEKEQSLQ 329
Query: 449 NEKVEVLKEQVSIKAAIKAANR 470
K E +K +V + K R
Sbjct: 330 ESKEECIKLKVDLLEQTKQGKR 351
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.125 0.334
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,055,409
Number of Sequences: 37866
Number of extensions: 893860
Number of successful extensions: 13237
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 371
Number of HSP's successfully gapped in prelim test: 1109
Number of HSP's that attempted gapping in prelim test: 5647
Number of HSP's gapped (non-prelim): 4427
length of query: 528
length of database: 18,247,518
effective HSP length: 107
effective length of query: 421
effective length of database: 14,195,856
effective search space: 5976455376
effective search space used: 5976455376
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.