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Search of human proteins with 8922652
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|8922652 ADP-ribosylation factor GTPase activating protein 1
isoform a [Homo sapiens]
(406 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|8922652 ADP-ribosylation factor GTPase activating protein 1 i... 845 0.0
gi|28416436 ADP-ribosylation factor GTPase activating protein 1 ... 828 0.0
gi|214829673 ADP-ribosylation factor GTPase activating protein 3... 120 3e-27
gi|31543983 ADP-ribosylation factor GTPase activating protein 2 ... 105 7e-23
gi|214829714 ADP-ribosylation factor GTPase activating protein 3... 94 2e-19
gi|206597522 ArfGAP with SH3 domain, ankyrin repeat and PH domai... 78 1e-14
gi|4502249 ArfGAP with SH3 domain, ankyrin repeat and PH domain ... 78 1e-14
gi|21264558 stromal membrane-associated GTPase-activating protei... 77 4e-14
gi|218563749 ArfGAP with coiled-coil, ankyrin repeat and PH doma... 76 5e-14
gi|23943872 small ArfGAP2 [Homo sapiens] 76 6e-14
gi|46094081 development and differentiation enhancing factor 1 [... 74 2e-13
gi|113204622 stromal membrane-associated GTPase-activating prote... 74 2e-13
gi|187608516 centaurin, beta 2 [Homo sapiens] 74 3e-13
gi|7661880 centaurin beta1 [Homo sapiens] 71 2e-12
gi|110227613 centaurin, gamma 3 isoform a [Homo sapiens] 71 2e-12
gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens] 70 3e-12
gi|7661962 centaurin, gamma 1 isoform PIKE-S [Homo sapiens] 70 3e-12
gi|221307473 ArfGAP with SH3 domain, ankyrin repeat and PH domai... 70 3e-12
gi|19923540 ArfGAP with SH3 domain, ankyrin repeat and PH domain... 70 3e-12
gi|6806913 centaurin, alpha 1 [Homo sapiens] 69 6e-12
gi|80978934 centaurin, gamma 2 isoform 2 [Homo sapiens] 67 4e-11
gi|80978930 centaurin, gamma 2 isoform 1 [Homo sapiens] 67 4e-11
gi|206597509 HIV-1 Rev binding protein isoform 4 [Homo sapiens] 66 5e-11
gi|166851846 centaurin, gamma-like family, member 3 [Homo sapiens] 65 1e-10
gi|148806877 ankyrin repeat and GTPase domain Arf GTPase activat... 64 2e-10
gi|206597507 HIV-1 Rev binding protein isoform 3 [Homo sapiens] 64 2e-10
gi|206597505 HIV-1 Rev binding protein isoform 1 [Homo sapiens] 64 2e-10
gi|38570132 HIV-1 Rev binding protein isoform 2 [Homo sapiens] 64 2e-10
gi|156104893 ArfGAP with GTPase domain, ankyrin repeat and PH do... 63 4e-10
gi|117956373 ArfGAP with GTPase domain, ankyrin repeat and PH do... 63 4e-10
>gi|8922652 ADP-ribosylation factor GTPase activating protein 1
isoform a [Homo sapiens]
Length = 406
Score = 845 bits (2183), Expect = 0.0
Identities = 406/406 (100%), Positives = 406/406 (100%)
Query: 1 MASPRTRKVLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVR 60
MASPRTRKVLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVR
Sbjct: 1 MASPRTRKVLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVR 60
Query: 61 SVTMDKWKDIELEKMKAGGNAKFREFLESQEDYDPCWSLQEKYNSRAAALFRDKVVALAE 120
SVTMDKWKDIELEKMKAGGNAKFREFLESQEDYDPCWSLQEKYNSRAAALFRDKVVALAE
Sbjct: 61 SVTMDKWKDIELEKMKAGGNAKFREFLESQEDYDPCWSLQEKYNSRAAALFRDKVVALAE 120
Query: 121 GREWSLESSPAQNWTPPQPRTLPSMVHRVSGQPQSVTASSDKAFEDWLNDDLGSYQGAQG 180
GREWSLESSPAQNWTPPQPRTLPSMVHRVSGQPQSVTASSDKAFEDWLNDDLGSYQGAQG
Sbjct: 121 GREWSLESSPAQNWTPPQPRTLPSMVHRVSGQPQSVTASSDKAFEDWLNDDLGSYQGAQG 180
Query: 181 NRYVGFGNTPPPQKKEDDFLNNAMSSLYSGWSSFTTGASRFASAAKEGATKFGSQASQKA 240
NRYVGFGNTPPPQKKEDDFLNNAMSSLYSGWSSFTTGASRFASAAKEGATKFGSQASQKA
Sbjct: 181 NRYVGFGNTPPPQKKEDDFLNNAMSSLYSGWSSFTTGASRFASAAKEGATKFGSQASQKA 240
Query: 241 SELGHSLNENVLKPAQEKVKEGKIFDDVSSGVSQLASKVQGVGSKGWRDVTTFFSGKAEG 300
SELGHSLNENVLKPAQEKVKEGKIFDDVSSGVSQLASKVQGVGSKGWRDVTTFFSGKAEG
Sbjct: 241 SELGHSLNENVLKPAQEKVKEGKIFDDVSSGVSQLASKVQGVGSKGWRDVTTFFSGKAEG 300
Query: 301 PLDSPSEGHSYQNSGLDHFQNSNIDQSFWETFGSAEPTKTRKSPSSDSWTCADTSTERRS 360
PLDSPSEGHSYQNSGLDHFQNSNIDQSFWETFGSAEPTKTRKSPSSDSWTCADTSTERRS
Sbjct: 301 PLDSPSEGHSYQNSGLDHFQNSNIDQSFWETFGSAEPTKTRKSPSSDSWTCADTSTERRS 360
Query: 361 SDSWEVWGSASTNRNSNSDGGEGGEGTKKAVPPAVPTDDGWDNQNW 406
SDSWEVWGSASTNRNSNSDGGEGGEGTKKAVPPAVPTDDGWDNQNW
Sbjct: 361 SDSWEVWGSASTNRNSNSDGGEGGEGTKKAVPPAVPTDDGWDNQNW 406
>gi|28416436 ADP-ribosylation factor GTPase activating protein 1
isoform b [Homo sapiens]
Length = 414
Score = 828 bits (2140), Expect = 0.0
Identities = 404/416 (97%), Positives = 404/416 (97%), Gaps = 12/416 (2%)
Query: 1 MASPRTRKVLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVR 60
MASPRTRKVLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVR
Sbjct: 1 MASPRTRKVLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVR 60
Query: 61 SVTMDKWKDIELEKMKAGGNAKFREFLESQEDYDPCWSLQEKYNSRAAALFRDKVVALAE 120
SVTMDKWKDIELEKMKAGGNAKFREFLESQEDYDPCWSLQEKYNSRAAALFRDKVVALAE
Sbjct: 61 SVTMDKWKDIELEKMKAGGNAKFREFLESQEDYDPCWSLQEKYNSRAAALFRDKVVALAE 120
Query: 121 GREWSLESSPAQNWTPPQPRTLPSMVHRVSGQPQSVTASSDKAFEDWLNDDLGSYQGAQG 180
GREWSLESSPAQNWTPPQPRTLPSMVHRVSGQPQSVTASSDKAFEDWLNDDLGSYQGAQG
Sbjct: 121 GREWSLESSPAQNWTPPQPRTLPSMVHRVSGQPQSVTASSDKAFEDWLNDDLGSYQGAQG 180
Query: 181 NRYVGFGNTPPPQKKEDDFLNNAMSSLYSGWSSFTTGASRFASAAKEGATKFGSQASQK- 239
NRYVGFGNTPPPQKKEDDFLNNAMSSLYSGWSSFTTGASRFASAAKEGATKFGSQASQK
Sbjct: 181 NRYVGFGNTPPPQKKEDDFLNNAMSSLYSGWSSFTTGASRFASAAKEGATKFGSQASQKF 240
Query: 240 ---------ASELGHSLNENVLKPAQEKVKEGKIFDDVSSGVSQLASKVQGVGSKGWRDV 290
ASELGHSLNENVLKPAQEKVKEGKIFDDVSSGVSQLASK GVGSKGWRDV
Sbjct: 241 WGHKQQPEPASELGHSLNENVLKPAQEKVKEGKIFDDVSSGVSQLASK--GVGSKGWRDV 298
Query: 291 TTFFSGKAEGPLDSPSEGHSYQNSGLDHFQNSNIDQSFWETFGSAEPTKTRKSPSSDSWT 350
TTFFSGKAEGPLDSPSEGHSYQNSGLDHFQNSNIDQSFWETFGSAEPTKTRKSPSSDSWT
Sbjct: 299 TTFFSGKAEGPLDSPSEGHSYQNSGLDHFQNSNIDQSFWETFGSAEPTKTRKSPSSDSWT 358
Query: 351 CADTSTERRSSDSWEVWGSASTNRNSNSDGGEGGEGTKKAVPPAVPTDDGWDNQNW 406
CADTSTERRSSDSWEVWGSASTNRNSNSDGGEGGEGTKKAVPPAVPTDDGWDNQNW
Sbjct: 359 CADTSTERRSSDSWEVWGSASTNRNSNSDGGEGGEGTKKAVPPAVPTDDGWDNQNW 414
>gi|214829673 ADP-ribosylation factor GTPase activating protein 3
isoform 1 [Homo sapiens]
Length = 516
Score = 120 bits (300), Expect = 3e-27
Identities = 116/393 (29%), Positives = 170/393 (43%), Gaps = 59/393 (15%)
Query: 9 VLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVRSVTMD-KW 67
+ K +R N VCF+CGA NP W S+TYG+++C++CSG HR LGVHLSF+RS +D W
Sbjct: 12 IFKRLRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFIRSTELDSNW 71
Query: 68 KDIELEKMKAGGNAKFREFLESQEDYDPCWSLQEKYNSRAAALFRDKVVALA------EG 121
+L M+ GGNA F KYNSRAA L+R+K+ +LA G
Sbjct: 72 SWFQLRCMQVGGNASASSFFHQHGCSTN--DTNAKYNSRAAQLYREKIKSLASQATRKHG 129
Query: 122 REWSLESSPAQNWTPP-----------QPRTLPSMVHRVSGQPQSVTASSDKAFEDWLND 170
+ L+S +PP P + +P S+T+ + E L +
Sbjct: 130 TDLWLDSCVVPPLSPPPKEEDFFASHVSPEVSDTAWASAIAEPSSLTS---RPVETTLEN 186
Query: 171 DLGSYQGAQGNRYVGFGNTPPPQKKEDDFLNNAMSSLYSGWSSFTTGASRFASAAKEG-A 229
+ G + QG G N P E +SS+ + + AK+G
Sbjct: 187 NEGGQE--QGPSVEGL-NVPTKATLE-------VSSI----------IKKKPNQAKKGLG 226
Query: 230 TKFGSQASQKASELGHSLNENVLKPAQ--EKVKE----GKIFDDVSSGVSQLASKVQGVG 283
K GS +QK L ++ + K AQ +K+KE K+ S VS L + +
Sbjct: 227 AKKGSLGAQK---LANTCFNEIEKQAQAADKMKEQEDLAKVVSKEESIVSSLRLAYKDLE 283
Query: 284 SKGWRDVTTFFSGKAEGPLDSPSEGHSYQNSGLDHFQNSNIDQSFWETFGSAEPTKTRKS 343
+ +D SGK D G S + H S++ E+ A+P K
Sbjct: 284 IQMKKDEKMNISGKKNVDSDRLGMGFGNCRSVISHSVTSDMQTIEQESPIMAKPRKKYND 343
Query: 344 PSSDSWTCADTS-----TERRSSDSWEVWGSAS 371
S DS+ + +S E RSS S+ W +S
Sbjct: 344 DSDDSYFTSSSSYFDEPVELRSS-SFSSWDDSS 375
>gi|31543983 ADP-ribosylation factor GTPase activating protein 2
[Homo sapiens]
Length = 521
Score = 105 bits (262), Expect = 7e-23
Identities = 76/259 (29%), Positives = 113/259 (43%), Gaps = 11/259 (4%)
Query: 9 VLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVRSVTMD-KW 67
+ K +R N CF+CGA NP W S+TYG+++C++CSG HR LGVHLSF+RS +D W
Sbjct: 13 LFKRLRAVPTNKACFDCGAKNPSWASITYGVFLCIDCSGVHRSLGVHLSFIRSTELDSNW 72
Query: 68 KDIELEKMKAGGNAKFREFLESQEDYDPCWSLQEKYNSRAAALFRDKVVALAEGREWSLE 127
+L M+ GGNA F ++ KYNSRAA ++R+K+ L +L
Sbjct: 73 NWFQLRCMQVGGNANATAFF--RQHGCTANDANTKYNSRAAQMYREKIRQLGSA---ALA 127
Query: 128 SSPAQNWTPPQPRTLPSMVHRVSGQPQSVTASSDKAFEDWLNDDLGSYQGAQGNRYVGFG 187
W +P+ + A++ + G+ Q A G
Sbjct: 128 RHGTDLWIDNMSSAVPNHSPEKKDSDFFTEHTQPPAWDAPATEPSGTQQPAPSTESSGLA 187
Query: 188 NTPPPQKKEDDFLNNAMSSLYSGWSSFTTGASRFASAAKEGATKFGSQASQKASELGHSL 247
P D L + + SS + +AAK+G +QK S S
Sbjct: 188 Q--PEHGPNTDLLGTSPKASLELKSSII--GKKKPAAAKKGLGAKKGLGAQKVSSQSFSE 243
Query: 248 NENVLKPAQEKVKEGKIFD 266
E + A EK++E + D
Sbjct: 244 IERQAQVA-EKLREQQAAD 261
>gi|214829714 ADP-ribosylation factor GTPase activating protein 3
isoform 2 [Homo sapiens]
Length = 472
Score = 94.4 bits (233), Expect = 2e-19
Identities = 105/376 (27%), Positives = 156/376 (41%), Gaps = 69/376 (18%)
Query: 9 VLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVRSVTMDK-W 67
+ K +R N VCF+CGA NP W S+TYG+++C++CSG HR LGVHLSF+RS +D W
Sbjct: 12 IFKRLRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFIRSTELDSNW 71
Query: 68 KDIELEKMKAGGNAKFREFLESQEDYDPCWSLQEKYNSRAAALFRDKVVALAEGREWSLE 127
+L M+ GGN A+AL+ D V E
Sbjct: 72 SWFQLRCMQVGGN--------------------------ASALWLDSCVVPPLSPPPKEE 105
Query: 128 SSPAQNWTPPQPRTLPSMVHRVSGQPQSVTASSDKAFEDWLNDDLGSYQGAQGNRYVGFG 187
A + +P T + +P S+T+ + E L ++ G + QG G
Sbjct: 106 DFFASHVSPEVSDTAWASA---IAEPSSLTS---RPVETTLENNEGGQE--QGPSVEGL- 156
Query: 188 NTPPPQKKEDDFLNNAMSSLYSGWSSFTTGASRFASAAKEG-ATKFGSQASQKASELGHS 246
N P E +SS+ + + AK+G K GS +QK L ++
Sbjct: 157 NVPTKATLE-------VSSIIK----------KKPNQAKKGLGAKKGSLGAQK---LANT 196
Query: 247 LNENVLKPAQ--EKVKE----GKIFDDVSSGVSQLASKVQGVGSKGWRDVTTFFSGKAEG 300
+ K AQ +K+KE K+ S VS L + + + +D SGK
Sbjct: 197 CFNEIEKQAQAADKMKEQEDLAKVVSKEESIVSSLRLAYKDLEIQMKKDEKMNISGKKNV 256
Query: 301 PLDSPSEGHSYQNSGLDHFQNSNIDQSFWETFGSAEPTKTRKSPSSDSWTCADTS----- 355
D G S + H S++ E+ A+P K S DS+ + +S
Sbjct: 257 DSDRLGMGFGNCRSVISHSVTSDMQTIEQESPIMAKPRKKYNDDSDDSYFTSSSSYFDEP 316
Query: 356 TERRSSDSWEVWGSAS 371
E RSS S+ W +S
Sbjct: 317 VELRSS-SFSSWDDSS 331
>gi|206597522 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
isoform b [Homo sapiens]
Length = 961
Score = 78.2 bits (191), Expect = 1e-14
Identities = 38/83 (45%), Positives = 53/83 (63%)
Query: 6 TRKVLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVRSVTMD 65
T++++ EV+ N+VC +CGA +P W+S GI C+ECSG HR LGVH S ++S+T+D
Sbjct: 420 TKEIISEVQRMTGNDVCCDCGAPDPTWLSTNLGILTCIECSGIHRELGVHYSRMQSLTLD 479
Query: 66 KWKDIELEKMKAGGNAKFREFLE 88
EL K GNA F E +E
Sbjct: 480 VLGTSELLLAKNIGNAGFNEIME 502
>gi|4502249 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
isoform a [Homo sapiens]
Length = 1006
Score = 78.2 bits (191), Expect = 1e-14
Identities = 38/83 (45%), Positives = 53/83 (63%)
Query: 6 TRKVLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVRSVTMD 65
T++++ EV+ N+VC +CGA +P W+S GI C+ECSG HR LGVH S ++S+T+D
Sbjct: 420 TKEIISEVQRMTGNDVCCDCGAPDPTWLSTNLGILTCIECSGIHRELGVHYSRMQSLTLD 479
Query: 66 KWKDIELEKMKAGGNAKFREFLE 88
EL K GNA F E +E
Sbjct: 480 VLGTSELLLAKNIGNAGFNEIME 502
>gi|21264558 stromal membrane-associated GTPase-activating protein 1
isoform B [Homo sapiens]
Length = 440
Score = 76.6 bits (187), Expect = 4e-14
Identities = 53/211 (25%), Positives = 92/211 (43%), Gaps = 18/211 (8%)
Query: 9 VLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVRSVTMDKWK 68
+L ++ +++N C +C A P+W S G++IC+ C+G HR LGVH+S V+SV +D+W
Sbjct: 20 ILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQWT 79
Query: 69 DIELEKMKAGGNAKFR---------EFLESQEDYDPCWSLQEKYNSRAAALFRDKVVALA 119
+++ M+ GN K R F Q D + +++KY + + DK
Sbjct: 80 AEQIQCMQDMGNTKARLLYEANLPENFRRPQTDQAVEFFIRDKYEKKK---YYDKNAIAI 136
Query: 120 EGREWSLESSPAQNWTPPQPRTLPSMVHRVSGQPQSV----TASSDKAFEDWLNDDLGSY 175
+E + + P+ P ++ + Q + + S KA E + DL
Sbjct: 137 TNKEKEKKKEEKKREKEPEKPAKPLTAEKLQKKDQQLEPKKSTSPKKAAEPTV--DLLGL 194
Query: 176 QGAQGNRYVGFGNTPPPQKKEDDFLNNAMSS 206
G T PP + D +S+
Sbjct: 195 DGPAVAPVTNGNTTVPPLNDDLDIFGPMISN 225
>gi|218563749 ArfGAP with coiled-coil, ankyrin repeat and PH domains
3 [Homo sapiens]
Length = 834
Score = 76.3 bits (186), Expect = 5e-14
Identities = 35/82 (42%), Positives = 52/82 (63%)
Query: 9 VLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVRSVTMDKWK 68
VL+ V+ N+ C +CG +P+W S+ G+ +C+ECSG HR LGVH S VRS+T+D W+
Sbjct: 405 VLQRVQSVAGNSQCGDCGQPDPRWASINLGVLLCIECSGIHRSLGVHCSKVRSLTLDSWE 464
Query: 69 DIELEKMKAGGNAKFREFLESQ 90
L+ M GN+ + E+Q
Sbjct: 465 PELLKLMCELGNSAVNQIYEAQ 486
>gi|23943872 small ArfGAP2 [Homo sapiens]
Length = 429
Score = 75.9 bits (185), Expect = 6e-14
Identities = 31/85 (36%), Positives = 53/85 (62%)
Query: 5 RTRKVLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVRSVTM 64
R + VL + ++++N C +C + P+W S G++IC+ C+G HR LGVH+S V+SV +
Sbjct: 11 RYQAVLANLLLEEDNKFCADCQSKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNL 70
Query: 65 DKWKDIELEKMKAGGNAKFREFLES 89
D+W +++ M+ GN K E+
Sbjct: 71 DQWTQEQIQCMQEMGNGKANRLYEA 95
>gi|46094081 development and differentiation enhancing factor 1
[Homo sapiens]
Length = 1129
Score = 74.3 bits (181), Expect = 2e-13
Identities = 32/84 (38%), Positives = 53/84 (63%)
Query: 6 TRKVLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVRSVTMD 65
T+ ++++V+ N++C +CG+ P W+S GI C+ECSG HR +GVH+S ++S+ +D
Sbjct: 438 TKAIIEDVQRLPGNDICCDCGSSEPTWLSTNLGILTCIECSGIHREMGVHISRIQSLELD 497
Query: 66 KWKDIELEKMKAGGNAKFREFLES 89
K EL K GN F + +E+
Sbjct: 498 KLGTSELLLAKNVGNNSFNDIMEA 521
>gi|113204622 stromal membrane-associated GTPase-activating protein
1 isoform A [Homo sapiens]
Length = 467
Score = 74.3 bits (181), Expect = 2e-13
Identities = 31/81 (38%), Positives = 52/81 (64%)
Query: 9 VLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVRSVTMDKWK 68
+L ++ +++N C +C A P+W S G++IC+ C+G HR LGVH+S V+SV +D+W
Sbjct: 20 ILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQWT 79
Query: 69 DIELEKMKAGGNAKFREFLES 89
+++ M+ GN K R E+
Sbjct: 80 AEQIQCMQDMGNTKARLLYEA 100
>gi|187608516 centaurin, beta 2 [Homo sapiens]
Length = 778
Score = 73.6 bits (179), Expect = 3e-13
Identities = 42/123 (34%), Positives = 60/123 (48%)
Query: 10 LKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVRSVTMDKWKD 69
L+ V+ N C +CG +P+W S+ GI +C+ECSG HR LGVH S VRS+T+D W+
Sbjct: 402 LQRVQCIPGNASCCDCGLADPRWASINLGITLCIECSGIHRSLGVHFSKVRSLTLDTWEP 461
Query: 70 IELEKMKAGGNAKFREFLESQEDYDPCWSLQEKYNSRAAALFRDKVVALAEGREWSLESS 129
L+ M GN E+ + Q A R K V ++S+ S
Sbjct: 462 ELLKLMCELGNDVINRVYEANVEKMGIKKPQPGQRQEKEAYIRAKYVERKFVDKYSISLS 521
Query: 130 PAQ 132
P +
Sbjct: 522 PPE 524
>gi|7661880 centaurin beta1 [Homo sapiens]
Length = 740
Score = 71.2 bits (173), Expect = 2e-12
Identities = 54/196 (27%), Positives = 82/196 (41%), Gaps = 35/196 (17%)
Query: 9 VLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVRSVTMDKWK 68
V+ +V+ D N C +C P+W S+ G+ +C++CSG HR LGVH S VRS+T+D W+
Sbjct: 407 VVAQVQSVDGNAQCCDCREPAPEWASINLGVTLCIQCSGIHRSLGVHFSKVRSLTLDSWE 466
Query: 69 DIELEKMKAGGNAKFREFLESQEDY------DPCWSLQEKYNSRAAALFRDKVVAL---A 119
++ M GN + E++ + P S QEK A K +
Sbjct: 467 PELVKLMCELGNVIINQIYEARVEAMAVKKPGPSCSRQEKEAWIHAKYVEKKFLTKLPEI 526
Query: 120 EGREWSLESSPAQNWTPPQPRTLP----------------------SMVHRVSGQPQSVT 157
GR Q PP+P P +++ R SG P S+
Sbjct: 527 RGRRGGRGRPRGQPPVPPKPSIRPRPGSLRSKPEPPSEDLGSLHPGALLFRASGHPPSLP 586
Query: 158 ASSDK----AFEDWLN 169
+D A +W+N
Sbjct: 587 TMADALAHGADVNWVN 602
>gi|110227613 centaurin, gamma 3 isoform a [Homo sapiens]
Length = 911
Score = 70.9 bits (172), Expect = 2e-12
Identities = 34/72 (47%), Positives = 43/72 (59%)
Query: 10 LKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVRSVTMDKWKD 69
++ VR N+ C +C A NP W S+ G +C+ECSG HR LG HLS VRS+ +D W
Sbjct: 665 VQAVRTVRGNSFCIDCDAPNPDWASLNLGALMCIECSGIHRHLGAHLSRVRSLDLDDWPP 724
Query: 70 IELEKMKAGGNA 81
L M A GNA
Sbjct: 725 ELLAVMTAMGNA 736
>gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens]
Length = 1192
Score = 70.5 bits (171), Expect = 3e-12
Identities = 29/58 (50%), Positives = 39/58 (67%)
Query: 10 LKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVRSVTMDKW 67
++ +R N++C +CGA NP W S+ G IC+ECSG HR LG HLS VRS+ +D W
Sbjct: 934 IQAIRNAKGNSICVDCGAPNPTWASLNLGALICIECSGIHRNLGTHLSRVRSLDLDDW 991
>gi|7661962 centaurin, gamma 1 isoform PIKE-S [Homo sapiens]
Length = 836
Score = 70.5 bits (171), Expect = 3e-12
Identities = 29/58 (50%), Positives = 39/58 (67%)
Query: 10 LKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVRSVTMDKW 67
++ +R N++C +CGA NP W S+ G IC+ECSG HR LG HLS VRS+ +D W
Sbjct: 578 IQAIRNAKGNSICVDCGAPNPTWASLNLGALICIECSGIHRNLGTHLSRVRSLDLDDW 635
>gi|221307473 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
isoform b [Homo sapiens]
Length = 894
Score = 70.1 bits (170), Expect = 3e-12
Identities = 33/85 (38%), Positives = 51/85 (60%)
Query: 6 TRKVLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVRSVTMD 65
T+ ++ EV+ + N+ C +CGA +P W+S G+ C++CSG HR LGV S ++S+T+D
Sbjct: 416 TKLLIAEVKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHRELGVRFSRMQSLTLD 475
Query: 66 KWKDIELEKMKAGGNAKFREFLESQ 90
EL GN F E +E+Q
Sbjct: 476 LLGPSELLLALNMGNTSFNEVMEAQ 500
>gi|19923540 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
isoform a [Homo sapiens]
Length = 903
Score = 70.1 bits (170), Expect = 3e-12
Identities = 33/85 (38%), Positives = 51/85 (60%)
Query: 6 TRKVLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVRSVTMD 65
T+ ++ EV+ + N+ C +CGA +P W+S G+ C++CSG HR LGV S ++S+T+D
Sbjct: 425 TKLLIAEVKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHRELGVRFSRMQSLTLD 484
Query: 66 KWKDIELEKMKAGGNAKFREFLESQ 90
EL GN F E +E+Q
Sbjct: 485 LLGPSELLLALNMGNTSFNEVMEAQ 509
>gi|6806913 centaurin, alpha 1 [Homo sapiens]
Length = 374
Score = 69.3 bits (168), Expect = 6e-12
Identities = 38/90 (42%), Positives = 54/90 (60%), Gaps = 2/90 (2%)
Query: 1 MASPRTRKVLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVR 60
MA R R VL E+ + N C +CGA +P W S T G++ICL CSG HR + +S V+
Sbjct: 1 MAKERRRAVL-ELLQRPGNARCADCGAPDPDWASYTLGVFICLSCSGIHRNI-PQVSKVK 58
Query: 61 SVTMDKWKDIELEKMKAGGNAKFREFLESQ 90
SV +D W++ ++E M + GN R ES+
Sbjct: 59 SVRLDAWEEAQVEFMASHGNDAARARFESK 88
>gi|80978934 centaurin, gamma 2 isoform 2 [Homo sapiens]
Length = 804
Score = 66.6 bits (161), Expect = 4e-11
Identities = 31/80 (38%), Positives = 44/80 (55%)
Query: 1 MASPRTRKVLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVR 60
+ S L+ +R N+ C +C NP W S+ G +C+ECSG HR LG HLS VR
Sbjct: 550 LTSQSEAMALQSIRNMRGNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLGTHLSRVR 609
Query: 61 SVTMDKWKDIELEKMKAGGN 80
S+ +D W ++ M + GN
Sbjct: 610 SLDLDDWPVELIKVMSSIGN 629
>gi|80978930 centaurin, gamma 2 isoform 1 [Homo sapiens]
Length = 857
Score = 66.6 bits (161), Expect = 4e-11
Identities = 31/80 (38%), Positives = 44/80 (55%)
Query: 1 MASPRTRKVLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVR 60
+ S L+ +R N+ C +C NP W S+ G +C+ECSG HR LG HLS VR
Sbjct: 603 LTSQSEAMALQSIRNMRGNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLGTHLSRVR 662
Query: 61 SVTMDKWKDIELEKMKAGGN 80
S+ +D W ++ M + GN
Sbjct: 663 SLDLDDWPVELIKVMSSIGN 682
>gi|206597509 HIV-1 Rev binding protein isoform 4 [Homo sapiens]
Length = 522
Score = 66.2 bits (160), Expect = 5e-11
Identities = 62/242 (25%), Positives = 108/242 (44%), Gaps = 23/242 (9%)
Query: 8 KVLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVRSVTMDKW 67
K+L+++ N CF+C P +V++T G ++C CSG RGL V+S++M +
Sbjct: 15 KMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLNPP-HRVKSISMTTF 73
Query: 68 KDIELEKMKAGGNAKFREFLESQEDYDPCWSLQEKYNSRAAALFRDKVVALAEGREWSLE 127
E+E ++ GN ++ W S A FRD + +E+ E
Sbjct: 74 TQQEIEFLQKHGNEVCKQI----------WLGLFDDRSSAIPDFRDP----QKVKEFLQE 119
Query: 128 SSPAQNW-TPPQPRTLPSMVH-RVSGQPQSVTASSD--KAFEDWLNDDLGSYQGAQG--- 180
+ W PP+ + + VH +SG S T+S+ K + L D + +G
Sbjct: 120 KYEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPS 179
Query: 181 -NRYVGFGNTPPPQKKEDDFLNNAMSSLYSGWSSFTTGASRFASAAKEGATKFGSQASQK 239
+ VG +KK+ D L++ S +++ + +T + FA+ A + GS AS
Sbjct: 180 QSPVVGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAGGSAASVN 239
Query: 240 AS 241
A+
Sbjct: 240 AN 241
>gi|166851846 centaurin, gamma-like family, member 3 [Homo sapiens]
Length = 686
Score = 65.1 bits (157), Expect = 1e-10
Identities = 30/75 (40%), Positives = 44/75 (58%), Gaps = 1/75 (1%)
Query: 1 MASPRTRKVLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVR 60
+ S L+ ++ N C +C NP+W S+ G+ +C+ECSG HR LG HLS VR
Sbjct: 458 LTSQSEAMALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSLGPHLSRVR 517
Query: 61 SVTMDKWKDIELEKM 75
S+ +D W +EL K+
Sbjct: 518 SLELDDW-PVELRKV 531
>gi|148806877 ankyrin repeat and GTPase domain Arf GTPase activating
protein 11 [Homo sapiens]
Length = 550
Score = 64.3 bits (155), Expect = 2e-10
Identities = 32/81 (39%), Positives = 47/81 (58%), Gaps = 2/81 (2%)
Query: 1 MASPRTRKVLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVR 60
+ S L+ ++ N+ C +C NP+W S+ G+ +C+ECSG HR LG LS VR
Sbjct: 322 LTSQSEAMALQSIQNMRGNSHCVDCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVR 381
Query: 61 SVTMDKWKDIELEK-MKAGGN 80
S+ +D W +EL K M + GN
Sbjct: 382 SLELDDW-PVELRKVMSSIGN 401
>gi|206597507 HIV-1 Rev binding protein isoform 3 [Homo sapiens]
Length = 560
Score = 63.9 bits (154), Expect = 2e-10
Identities = 61/242 (25%), Positives = 108/242 (44%), Gaps = 28/242 (11%)
Query: 8 KVLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVRSVTMDKW 67
K+L+++ N CF+C P +V++T G ++C CSG RGL V+S++M +
Sbjct: 15 KMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLNPP-HRVKSISMTTF 73
Query: 68 KDIELEKMKAGGNAKFREFLESQEDYDPCWSLQEKYNSRAAALFRDKVVALAEGREWSLE 127
E+E ++ GN ++ W S A FRD + +E+ E
Sbjct: 74 TQQEIEFLQKHGNEVCKQI----------WLGLFDDRSSAIPDFRDP----QKVKEFLQE 119
Query: 128 SSPAQNW-TPPQPRTLPSMVH-RVSGQPQSVTASSD--KAFEDWLNDDLGSYQGAQG--- 180
+ W PP+ + + VH +SG S T+S+ K + L D + +G
Sbjct: 120 KYEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPS 179
Query: 181 -NRYVGFGNTPPPQKKEDDFLNNAMSSLYSGWSSFTTGASRFASAAKEGATKFGSQASQK 239
+ VG +KK+ D L++ S +++ + +T + FA+ A F S A+Q
Sbjct: 180 QSPVVGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFA-----HFNSHAAQN 234
Query: 240 AS 241
++
Sbjct: 235 SA 236
>gi|206597505 HIV-1 Rev binding protein isoform 1 [Homo sapiens]
Length = 584
Score = 63.9 bits (154), Expect = 2e-10
Identities = 61/242 (25%), Positives = 108/242 (44%), Gaps = 28/242 (11%)
Query: 8 KVLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVRSVTMDKW 67
K+L+++ N CF+C P +V++T G ++C CSG RGL V+S++M +
Sbjct: 15 KMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLNPP-HRVKSISMTTF 73
Query: 68 KDIELEKMKAGGNAKFREFLESQEDYDPCWSLQEKYNSRAAALFRDKVVALAEGREWSLE 127
E+E ++ GN ++ W S A FRD + +E+ E
Sbjct: 74 TQQEIEFLQKHGNEVCKQI----------WLGLFDDRSSAIPDFRDP----QKVKEFLQE 119
Query: 128 SSPAQNW-TPPQPRTLPSMVH-RVSGQPQSVTASSD--KAFEDWLNDDLGSYQGAQG--- 180
+ W PP+ + + VH +SG S T+S+ K + L D + +G
Sbjct: 120 KYEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPS 179
Query: 181 -NRYVGFGNTPPPQKKEDDFLNNAMSSLYSGWSSFTTGASRFASAAKEGATKFGSQASQK 239
+ VG +KK+ D L++ S +++ + +T + FA+ A F S A+Q
Sbjct: 180 QSPVVGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFA-----HFNSHAAQN 234
Query: 240 AS 241
++
Sbjct: 235 SA 236
>gi|38570132 HIV-1 Rev binding protein isoform 2 [Homo sapiens]
Length = 562
Score = 63.9 bits (154), Expect = 2e-10
Identities = 61/242 (25%), Positives = 108/242 (44%), Gaps = 28/242 (11%)
Query: 8 KVLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVRSVTMDKW 67
K+L+++ N CF+C P +V++T G ++C CSG RGL V+S++M +
Sbjct: 15 KMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLNPP-HRVKSISMTTF 73
Query: 68 KDIELEKMKAGGNAKFREFLESQEDYDPCWSLQEKYNSRAAALFRDKVVALAEGREWSLE 127
E+E ++ GN ++ W S A FRD + +E+ E
Sbjct: 74 TQQEIEFLQKHGNEVCKQI----------WLGLFDDRSSAIPDFRDP----QKVKEFLQE 119
Query: 128 SSPAQNW-TPPQPRTLPSMVH-RVSGQPQSVTASSD--KAFEDWLNDDLGSYQGAQG--- 180
+ W PP+ + + VH +SG S T+S+ K + L D + +G
Sbjct: 120 KYEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPS 179
Query: 181 -NRYVGFGNTPPPQKKEDDFLNNAMSSLYSGWSSFTTGASRFASAAKEGATKFGSQASQK 239
+ VG +KK+ D L++ S +++ + +T + FA+ A F S A+Q
Sbjct: 180 QSPVVGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFA-----HFNSHAAQN 234
Query: 240 AS 241
++
Sbjct: 235 SA 236
>gi|156104893 ArfGAP with GTPase domain, ankyrin repeat and PH
domain 4 [Homo sapiens]
Length = 663
Score = 63.2 bits (152), Expect = 4e-10
Identities = 32/81 (39%), Positives = 46/81 (56%), Gaps = 2/81 (2%)
Query: 1 MASPRTRKVLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVR 60
+ S L+ ++ N C +C NP+W S+ G+ +C+ECSG HR LG LS VR
Sbjct: 435 LTSQSKAMALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVR 494
Query: 61 SVTMDKWKDIELEK-MKAGGN 80
S+ +D W +EL K M + GN
Sbjct: 495 SLELDDW-PVELRKVMSSIGN 514
>gi|117956373 ArfGAP with GTPase domain, ankyrin repeat and PH
domain 7 [Homo sapiens]
Length = 663
Score = 63.2 bits (152), Expect = 4e-10
Identities = 32/81 (39%), Positives = 46/81 (56%), Gaps = 2/81 (2%)
Query: 1 MASPRTRKVLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVR 60
+ S L+ ++ N C +C NP+W S+ G+ +C+ECSG HR LG LS VR
Sbjct: 435 LTSQSEAMALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVR 494
Query: 61 SVTMDKWKDIELEK-MKAGGN 80
S+ +D W +EL K M + GN
Sbjct: 495 SLELDDW-PVELRKVMSSIGN 514
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.127 0.390
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,569,733
Number of Sequences: 37866
Number of extensions: 818286
Number of successful extensions: 2617
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 67
Number of HSP's successfully gapped in prelim test: 44
Number of HSP's that attempted gapping in prelim test: 2267
Number of HSP's gapped (non-prelim): 171
length of query: 406
length of database: 18,247,518
effective HSP length: 105
effective length of query: 301
effective length of database: 14,271,588
effective search space: 4295747988
effective search space used: 4295747988
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.