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Search of human proteins with 88758565
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|88758565 potassium voltage-gated channel, shaker-related
subfamily, member 3 [Homo sapiens]
(575 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|88758565 potassium voltage-gated channel, shaker-related subf... 1165 0.0
gi|4826782 potassium voltage-gated channel, shaker-related subfa... 712 0.0
gi|119395748 potassium voltage-gated channel subfamily A member ... 706 0.0
gi|4504817 potassium voltage-gated channel, shaker-related subfa... 667 0.0
gi|25952087 potassium voltage-gated channel, shaker-related subf... 636 0.0
gi|4504821 potassium voltage-gated channel, shaker-related subfa... 634 0.0
gi|25952092 potassium voltage-gated channel, shaker-related subf... 582 e-166
gi|5031819 potassium voltage-gated channel, shaker-related subfa... 577 e-164
gi|27436981 potassium voltage-gated channel, Shal-related subfam... 278 1e-74
gi|27436974 potassium voltage-gated channel, Shab-related subfam... 269 6e-72
gi|4826784 potassium voltage-gated channel, Shab-related subfami... 268 8e-72
gi|4826786 Shaw-related voltage-gated potassium channel protein ... 265 7e-71
gi|163792201 Shaw-related voltage-gated potassium channel protei... 265 7e-71
gi|27436984 potassium voltage-gated channel, Shal-related subfam... 263 2e-70
gi|27436986 potassium voltage-gated channel, Shal-related subfam... 263 2e-70
gi|9789987 potassium voltage-gated channel, Shal-related subfami... 262 7e-70
gi|88758576 Shaw-related voltage-gated potassium channel protein... 255 9e-68
gi|24497462 Shaw-related voltage-gated potassium channel protein... 255 9e-68
gi|24497464 Shaw-related voltage-gated potassium channel protein... 255 9e-68
gi|21217561 Shaw-related voltage-gated potassium channel protein... 245 7e-65
gi|21217563 Shaw-related voltage-gated potassium channel protein... 245 7e-65
gi|24497458 Shaw-related voltage-gated potassium channel protein... 245 7e-65
gi|13492973 potassium voltage-gated channel delayed-rectifier pr... 236 6e-62
gi|20070166 potassium voltage-gated channel, subfamily F, member... 234 1e-61
gi|25952108 potassium voltage-gated channel delayed-rectifier pr... 231 2e-60
gi|24497460 Shaw-related voltage-gated potassium channel protein... 230 3e-60
gi|45383011 potassium voltage-gated channel, delayed-rectifier, ... 227 3e-59
gi|19071574 potassium voltage-gated channel, subfamily G, member... 214 1e-55
gi|27436993 potassium voltage-gated channel, subfamily G, member... 209 4e-54
gi|27436988 potassium voltage-gated channel, subfamily G, member... 209 6e-54
>gi|88758565 potassium voltage-gated channel, shaker-related
subfamily, member 3 [Homo sapiens]
Length = 575
Score = 1165 bits (3013), Expect = 0.0
Identities = 575/575 (100%), Positives = 575/575 (100%)
Query: 1 MDERLSLLRSPPPPSARHRAHPPQRPASSGGAHTLVNHGYAEPAAGRELPPDMTVVPGDH 60
MDERLSLLRSPPPPSARHRAHPPQRPASSGGAHTLVNHGYAEPAAGRELPPDMTVVPGDH
Sbjct: 1 MDERLSLLRSPPPPSARHRAHPPQRPASSGGAHTLVNHGYAEPAAGRELPPDMTVVPGDH 60
Query: 61 LLEPEVADGGGAPPQGGCGGGGCDRYEPLPPSLPAAGEQDCCGERVVINISGLRFETQLK 120
LLEPEVADGGGAPPQGGCGGGGCDRYEPLPPSLPAAGEQDCCGERVVINISGLRFETQLK
Sbjct: 61 LLEPEVADGGGAPPQGGCGGGGCDRYEPLPPSLPAAGEQDCCGERVVINISGLRFETQLK 120
Query: 121 TLCQFPETLLGDPKRRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRIRRPVNVPIDIF 180
TLCQFPETLLGDPKRRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRIRRPVNVPIDIF
Sbjct: 121 TLCQFPETLLGDPKRRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRIRRPVNVPIDIF 180
Query: 181 SEEIRFYQLGEEAMEKFREDEGFLREEERPLPRRDFQRQVWLLFEYPESSGPARGIAIVS 240
SEEIRFYQLGEEAMEKFREDEGFLREEERPLPRRDFQRQVWLLFEYPESSGPARGIAIVS
Sbjct: 181 SEEIRFYQLGEEAMEKFREDEGFLREEERPLPRRDFQRQVWLLFEYPESSGPARGIAIVS 240
Query: 241 VLVILISIVIFCLETLPEFRDEKDYPASTSQDSFEAAGNSTSGSRAGASSFSDPFFVVET 300
VLVILISIVIFCLETLPEFRDEKDYPASTSQDSFEAAGNSTSGSRAGASSFSDPFFVVET
Sbjct: 241 VLVILISIVIFCLETLPEFRDEKDYPASTSQDSFEAAGNSTSGSRAGASSFSDPFFVVET 300
Query: 301 LCIIWFSFELLVRFFACPSKATFSRNIMNLIDIVAIIPYFITLGTELAERQGNGQQAMSL 360
LCIIWFSFELLVRFFACPSKATFSRNIMNLIDIVAIIPYFITLGTELAERQGNGQQAMSL
Sbjct: 301 LCIIWFSFELLVRFFACPSKATFSRNIMNLIDIVAIIPYFITLGTELAERQGNGQQAMSL 360
Query: 361 AILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAE 420
AILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAE
Sbjct: 361 AILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAE 420
Query: 421 ADDPTSGFSSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIV 480
ADDPTSGFSSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIV
Sbjct: 421 ADDPTSGFSSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIV 480
Query: 481 SNFNYFYHRETEGEEQSQYMHVGSCQHLSSSAEELRKARSNSTLSKSEYMVIEEGGMNHS 540
SNFNYFYHRETEGEEQSQYMHVGSCQHLSSSAEELRKARSNSTLSKSEYMVIEEGGMNHS
Sbjct: 481 SNFNYFYHRETEGEEQSQYMHVGSCQHLSSSAEELRKARSNSTLSKSEYMVIEEGGMNHS 540
Query: 541 AFPQTPFKTGNSTATCTTNNNPNSCVNIKKIFTDV 575
AFPQTPFKTGNSTATCTTNNNPNSCVNIKKIFTDV
Sbjct: 541 AFPQTPFKTGNSTATCTTNNNPNSCVNIKKIFTDV 575
>gi|4826782 potassium voltage-gated channel, shaker-related
subfamily, member 2 [Homo sapiens]
Length = 499
Score = 712 bits (1837), Expect = 0.0
Identities = 384/514 (74%), Positives = 422/514 (82%), Gaps = 21/514 (4%)
Query: 66 VADGGGAPPQGGCGGGGCDRYEPLPPSLPAAGEQDCCGERVVINISGLRFETQLKTLCQF 125
VA G A G D Y+P + +CC ERVVINISGLRFETQLKTL QF
Sbjct: 3 VATGDPADEAAALPGHPQDTYDP-------EADHECC-ERVVINISGLRFETQLKTLAQF 54
Query: 126 PETLLGDPKRRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRIRRPVNVPIDIFSEEIR 185
PETLLGDPK+RMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGR+RRPVNVP+DIFSEEIR
Sbjct: 55 PETLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFSEEIR 114
Query: 186 FYQLGEEAMEKFREDEGFLREEERPLPRRDFQRQVWLLFEYPESSGPARGIAIVSVLVIL 245
FY+LGEEAME FREDEG+++EEERPLP +FQRQVWLLFEYPESSGPAR IAIVSV+VIL
Sbjct: 115 FYELGEEAMEMFREDEGYIKEEERPLPENEFQRQVWLLFEYPESSGPARIIAIVSVMVIL 174
Query: 246 ISIVIFCLETLPEFRDEKDYPASTSQDSFEAAGNSTSGSRAGASSFSDPFFVVETLCIIW 305
ISIV FCLETLP FRDE + S +F NST G + ++SF+DPFF+VETLCIIW
Sbjct: 175 ISIVSFCLETLPIFRDENE-DMHGSGVTFHTYSNSTIGYQQ-STSFTDPFFIVETLCIIW 232
Query: 306 FSFELLVRFFACPSKATFSRNIMNLIDIVAIIPYFITLGTELAERQGN---GQQAMSLAI 362
FSFE LVRFFACPSKA F NIMN+IDIVAIIPYFITLGTELAE+ + GQQAMSLAI
Sbjct: 233 FSFEFLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTELAEKPEDAQQGQQAMSLAI 292
Query: 363 LRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEAD 422
LRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEAD
Sbjct: 293 LRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEAD 352
Query: 423 DPTSGFSSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIVSN 482
+ S F SIPDAFWWAVV+MTTVGYGDM P TIGGKIVGSLCAIAGVLTIALPVPVIVSN
Sbjct: 353 ERESQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSN 412
Query: 483 FNYFYHRETEGEEQSQYMHVGSCQHLSSSAEELRKARSNSTLSKSEYMVIEEGGMNHSAF 542
FNYFYHRETEGEEQ+QY+ V SC + SS +L+K+RS ST+SKS+YM I+E G+N+S
Sbjct: 413 FNYFYHRETEGEEQAQYLQVTSCPKIPSS-PDLKKSRSASTISKSDYMEIQE-GVNNS-- 468
Query: 543 PQTPFKTGN-STATCTTNNNPNSCVNIKKIFTDV 575
F+ N TA CT N + VNI K+ TDV
Sbjct: 469 -NEDFREENLKTANCTLAN--TNYVNITKMLTDV 499
>gi|119395748 potassium voltage-gated channel subfamily A member 1
[Homo sapiens]
Length = 495
Score = 706 bits (1823), Expect = 0.0
Identities = 380/528 (71%), Positives = 431/528 (81%), Gaps = 38/528 (7%)
Query: 53 MTVVPGDHLLEPEVADGGGAPPQGGCGGGGCDRYEPLPPSLPAAGEQDCCGERVVINISG 112
MTV+ G+++ E A G PQ G D + +CC ERVVINISG
Sbjct: 1 MTVMSGENVDEASAAPGH---PQDGSYPRQADH-----------DDHECC-ERVVINISG 45
Query: 113 LRFETQLKTLCQFPETLLGDPKRRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRIRRP 172
LRFETQLKTL QFP TLLG+PK+RMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGR+RRP
Sbjct: 46 LRFETQLKTLAQFPNTLLGNPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRP 105
Query: 173 VNVPIDIFSEEIRFYQLGEEAMEKFREDEGFLREEERPLPRRDFQRQVWLLFEYPESSGP 232
VNVP+D+FSEEI+FY+LGEEAMEKFREDEGF++EEERPLP +++QRQVWLLFEYPESSGP
Sbjct: 106 VNVPLDMFSEEIKFYELGEEAMEKFREDEGFIKEEERPLPEKEYQRQVWLLFEYPESSGP 165
Query: 233 ARGIAIVSVLVILISIVIFCLETLPEFRDEKDYPASTSQ-DSFEAAGNSTSGSRAGASSF 291
AR IAIVSV+VILISIVIFCLETLPE +D+KD+ + + D+ NS + F
Sbjct: 166 ARVIAIVSVMVILISIVIFCLETLPELKDDKDFTGTVHRIDNTTVIYNS--------NIF 217
Query: 292 SDPFFVVETLCIIWFSFELLVRFFACPSKATFSRNIMNLIDIVAIIPYFITLGTELAERQ 351
+DPFF+VETLCIIWFSFEL+VRFFACPSK F +NIMN IDIVAIIPYFITLGTE+AE++
Sbjct: 218 TDPFFIVETLCIIWFSFELVVRFFACPSKTDFFKNIMNFIDIVAIIPYFITLGTEIAEQE 277
Query: 352 GN--GQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGV 409
GN G+QA SLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGV
Sbjct: 278 GNQKGEQATSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGV 337
Query: 410 ILFSSAVYFAEADDPTSGFSSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGV 469
ILFSSAVYFAEA++ S FSSIPDAFWWAVV+MTTVGYGDM+PVTIGGKIVGSLCAIAGV
Sbjct: 338 ILFSSAVYFAEAEEAESHFSSIPDAFWWAVVSMTTVGYGDMYPVTIGGKIVGSLCAIAGV 397
Query: 470 LTIALPVPVIVSNFNYFYHRETEGEEQSQYMHVGSCQHLSSSAEELRKARSNSTLSKSEY 529
LTIALPVPVIVSNFNYFYHRETEGEEQ+Q +HV S +L+S ++ R RS+ST+SKSEY
Sbjct: 398 LTIALPVPVIVSNFNYFYHRETEGEEQAQLLHVSS-PNLASDSDLSR--RSSSTMSKSEY 454
Query: 530 MVIEEGGMNHSA--FPQTPFKTGNSTATCTTNNNPNSCVNIKKIFTDV 575
M IEE MN+S + Q +T N CTT N +CVN K+ TDV
Sbjct: 455 MEIEE-DMNNSIAHYRQVNIRTAN----CTTAN--QNCVNKSKLLTDV 495
>gi|4504817 potassium voltage-gated channel, shaker-related
subfamily, member 4 [Homo sapiens]
Length = 653
Score = 667 bits (1720), Expect = 0.0
Identities = 351/513 (68%), Positives = 405/513 (78%), Gaps = 27/513 (5%)
Query: 73 PPQGGCGGGGCDRYEPLPPSLPAAGEQDCCGERVVINISGLRFETQLKTLCQFPETLLGD 132
P G GG RY DCC ERVVIN+SGLRFETQ+KTL QFPETLLGD
Sbjct: 158 PQDEGGGGYSSVRYS------------DCC-ERVVINVSGLRFETQMKTLAQFPETLLGD 204
Query: 133 PKRRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRIRRPVNVPIDIFSEEIRFYQLGEE 192
P++R +YFDPLRNEYFFDRNRPSFDAILYYYQSGGR++RPVNVP DIF+EE++FYQLGEE
Sbjct: 205 PEKRTQYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLKRPVNVPFDIFTEEVKFYQLGEE 264
Query: 193 AMEKFREDEGFLREEE-RPLPRRDFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIF 251
A+ KFREDEGF+REEE R LP +F++Q+WLLFEYPESS PARGIAIVSVLVILISIVIF
Sbjct: 265 ALLKFREDEGFVREEEDRALPENEFKKQIWLLFEYPESSSPARGIAIVSVLVILISIVIF 324
Query: 252 CLETLPEFRDEKDYPASTSQDSFEAAGNSTSG---SRAGASSFSDPFFVVETLCIIWFSF 308
CLETLPEFRD++D + S N TS +G + F+DPFF+VET+CI+WFSF
Sbjct: 325 CLETLPEFRDDRDLVMALSAGGHGGLLNDTSAPHLENSGHTIFNDPFFIVETVCIVWFSF 384
Query: 309 ELLVRFFACPSKATFSRNIMNLIDIVAIIPYFITLGTELAERQGNG----QQAMSLAILR 364
E +VR FACPS+A F +NIMN+IDIV+I+PYFITLGT+LA++QG G QQAMS AILR
Sbjct: 385 EFVVRCFACPSQALFFKNIMNIIDIVSILPYFITLGTDLAQQQGGGNGQQQQAMSFAILR 444
Query: 365 VIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADDP 424
+IRLVRVFRIFKLSRHSKGLQILG TL+ASMRELGLLIFFLFIGVILFSSAVYFAEAD+P
Sbjct: 445 IIRLVRVFRIFKLSRHSKGLQILGHTLRASMRELGLLIFFLFIGVILFSSAVYFAEADEP 504
Query: 425 TSGFSSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFN 484
T+ F SIPDAFWWAVVTMTTVGYGDM P+T+GGKIVGSLCAIAGVLTIALPVPVIVSNFN
Sbjct: 505 TTHFQSIPDAFWWAVVTMTTVGYGDMKPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFN 564
Query: 485 YFYHRETEGEEQSQY-MHVGSCQHLSSS-AEELRKARSNSTLSKSEYMVIEEGGMNHSAF 542
YFYHRETE EEQ+Q + SC +L S+ ++ R + S+S KSEY+ +EE G+ S
Sbjct: 565 YFYHRETENEEQTQLTQNAVSCPYLPSNLLKKFRSSTSSSLGDKSEYLEMEE-GVKESLC 623
Query: 543 PQTPFKTGNSTATCTTNNNPNSCVNIKKIFTDV 575
+ G + T NN C N K + TDV
Sbjct: 624 AKEEKCQGKGDDSETDKNN---CSNAKAVETDV 653
>gi|25952087 potassium voltage-gated channel, shaker-related
subfamily, member 5 [Homo sapiens]
Length = 613
Score = 636 bits (1641), Expect = 0.0
Identities = 345/509 (67%), Positives = 387/509 (76%), Gaps = 40/509 (7%)
Query: 13 PPSARHRAHPPQRPASSG-GAHTLVNHGYAE----PAAG-RELPPDMTVVPGDHLLEPEV 66
PP+A + P+ PA G GA + G P G R LPP +P PE
Sbjct: 37 PPTAG-LSDGPKEPAPKGRGAQRDADSGVRPLPPLPDPGVRPLPPLPEELPRPRRPPPED 95
Query: 67 ADGGGAPPQGGCGGGGCDRYEPLPPSLPAAGEQDCCGERVVINISGLRFETQLKTLCQFP 126
+ G P G A G +RV INISGLRFETQL TL QFP
Sbjct: 96 EEEEGDPGLGTVED-------------QALGTASLHHQRVHINISGLRFETQLGTLAQFP 142
Query: 127 ETLLGDPKRRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRIRRPVNVPIDIFSEEIRF 186
TLLGDP +R+RYFDPLRNEYFFDRNRPSFD ILYYYQSGGR+RRPVNV +D+F++EIRF
Sbjct: 143 NTLLGDPAKRLRYFDPLRNEYFFDRNRPSFDGILYYYQSGGRLRRPVNVSLDVFADEIRF 202
Query: 187 YQLGEEAMEKFREDEGFLREEERPLPRRDFQRQVWLLFEYPESSGPARGIAIVSVLVILI 246
YQLG+EAME+FREDEGF++EEE+PLPR +FQRQVWL+FEYPESSG AR IAIVSVLVILI
Sbjct: 203 YQLGDEAMERFREDEGFIKEEEKPLPRNEFQRQVWLIFEYPESSGSARAIAIVSVLVILI 262
Query: 247 SIVIFCLETLPEFRDEKD---YPASTSQDSFEAAGNSTSGSRAGAS----------SFSD 293
SI+ FCLETLPEFRDE++ +P + Q A G + SG A S + +D
Sbjct: 263 SIITFCLETLPEFRDERELLRHPPAPHQPPAPAPGANGSGVMAPPSGPTVAPLLPRTLAD 322
Query: 294 PFFVVETLCIIWFSFELLVRFFACPSKATFSRNIMNLIDIVAIIPYFITLGTELAERQ-- 351
PFF+VET C+IWF+FELLVRFFACPSKA FSRNIMN+ID+VAI PYFITLGTELAE+Q
Sbjct: 323 PFFIVETTCVIWFTFELLVRFFACPSKAGFSRNIMNIIDVVAIFPYFITLGTELAEQQPG 382
Query: 352 -----GNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLF 406
NGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILG+TL+ASMRELGLLIFFLF
Sbjct: 383 GGGGGQNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGKTLQASMRELGLLIFFLF 442
Query: 407 IGVILFSSAVYFAEADDPTSGFSSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAI 466
IGVILFSSAVYFAEAD+ + FSSIPDAFWWAVVTMTTVGYGDM P+T+GGKIVGSLCAI
Sbjct: 443 IGVILFSSAVYFAEADNQGTHFSSIPDAFWWAVVTMTTVGYGDMRPITVGGKIVGSLCAI 502
Query: 467 AGVLTIALPVPVIVSNFNYFYHRETEGEE 495
AGVLTIALPVPVIVSNFNYFYHRET+ EE
Sbjct: 503 AGVLTIALPVPVIVSNFNYFYHRETDHEE 531
>gi|4504821 potassium voltage-gated channel, shaker-related
subfamily, member 6 [Homo sapiens]
Length = 529
Score = 634 bits (1635), Expect = 0.0
Identities = 340/481 (70%), Positives = 369/481 (76%), Gaps = 60/481 (12%)
Query: 63 EPEVADGGGAPPQGGCGGGGCDRYEPLPPSLPAAGEQDCCGERVVINISGLRFETQLKTL 122
E E D G P GG GGGC C ER+VINISGLRFETQL+TL
Sbjct: 19 EGEQQDAGDFPEAGG--GGGC-----------------CSSERLVINISGLRFETQLRTL 59
Query: 123 CQFPETLLGDPKRRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRIRRPVNVPIDIFSE 182
FP+TLLGDP RR+R+FDPLRNEYFFDRNRPSFDAILYYYQSGGR+RRPVNVP+DIF E
Sbjct: 60 SLFPDTLLGDPGRRVRFFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFLE 119
Query: 183 EIRFYQLGEEAMEKFREDEGFL---REEERPLPRRDFQRQVWLLFEYPESSGPARGIAIV 239
EIRFYQLG+EA+ FREDEG L E+E+PLP + FQRQVWLLFEYPESSGPARGIAIV
Sbjct: 120 EIRFYQLGDEALAAFREDEGCLPEGGEDEKPLPSQPFQRQVWLLFEYPESSGPARGIAIV 179
Query: 240 SVLVILISIVIFCLETLPEFRDE----------KDYPASTSQDSFE-------------- 275
SVLVILISIVIFCLETLP+FR + + P S E
Sbjct: 180 SVLVILISIVIFCLETLPQFRVDGRGGNNGGVSRVSPVSRGSQEEEEDEDDSYTFHHGIT 239
Query: 276 ----AAGNSTSGSRAGASSFSDPFFVVETLCIIWFSFELLVRFFACPSKATFSRNIMNLI 331
G S+S S G S F+DPFF+VETLCI+WF+FELLVRF ACPSK F RNIMN+I
Sbjct: 240 PGEMGTGGSSSLSTLGGSFFTDPFFLVETLCIVWFTFELLVRFSACPSKPAFFRNIMNII 299
Query: 332 DIVAIIPYFITLGTELAERQ----------GNGQQAMSLAILRVIRLVRVFRIFKLSRHS 381
D+VAI PYFITLGTEL ++Q NGQQAMSLAILRVIRLVRVFRIFKLSRHS
Sbjct: 300 DLVAIFPYFITLGTELVQQQEQQPASGGGGQNGQQAMSLAILRVIRLVRVFRIFKLSRHS 359
Query: 382 KGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADDPTSGFSSIPDAFWWAVVT 441
KGLQILG+TL+ASMRELGLLIFFLFIGVILFSSAVYFAEADD S F SIPDAFWWAVVT
Sbjct: 360 KGLQILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAEADDDDSLFPSIPDAFWWAVVT 419
Query: 442 MTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQSQYMH 501
MTTVGYGDM+P+T+GGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETE EEQ QY H
Sbjct: 420 MTTVGYGDMYPMTVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEQEEQGQYTH 479
Query: 502 V 502
V
Sbjct: 480 V 480
>gi|25952092 potassium voltage-gated channel, shaker-related
subfamily, member 7 [Homo sapiens]
Length = 456
Score = 582 bits (1500), Expect = e-166
Identities = 290/406 (71%), Positives = 337/406 (83%), Gaps = 5/406 (1%)
Query: 102 CGERVVINISGLRFETQLKTLCQFPETLLGDPKRRMRYFDPLRNEYFFDRNRPSFDAILY 161
C ER+V+N++GLRFET+ +TL +FP+TLLGDP RR R++D R EYFFDR+RPSFDA+LY
Sbjct: 11 CCERLVLNVAGLRFETRARTLGRFPDTLLGDPARRGRFYDDARREYFFDRHRPSFDAVLY 70
Query: 162 YYQSGGRIRRPVNVPIDIFSEEIRFYQLGEEAMEKFREDEGFLREEERPLPRRDFQRQVW 221
YYQSGGR+RRP +VP+D+F EE+ FY LG A+ + REDEG ERPLPRR F RQ+W
Sbjct: 71 YYQSGGRLRRPAHVPLDVFLEEVAFYGLGAAALARLREDEGCPVPPERPLPRRAFARQLW 130
Query: 222 LLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPEFRDEKD---YPASTSQDSFEAA- 277
LLFE+PESS AR +A+VSVLVIL+SIV+FCLETLP+FRD++D A+ + F A
Sbjct: 131 LLFEFPESSQAARVLAVVSVLVILVSIVVFCLETLPDFRDDRDGTGLAAAAAAGPFPAPL 190
Query: 278 -GNSTSGSRAGASSFSDPFFVVETLCIIWFSFELLVRFFACPSKATFSRNIMNLIDIVAI 336
G+S F+DPFFVVETLCI WFSFELLVR CPSKA F +N+MNLID VAI
Sbjct: 191 NGSSQMPGNPPRLPFNDPFFVVETLCICWFSFELLVRLLVCPSKAIFFKNVMNLIDFVAI 250
Query: 337 IPYFITLGTELAERQGNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMR 396
+PYF+ LGTELA ++G GQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTL+ASMR
Sbjct: 251 LPYFVALGTELARQRGVGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLRASMR 310
Query: 397 ELGLLIFFLFIGVILFSSAVYFAEADDPTSGFSSIPDAFWWAVVTMTTVGYGDMHPVTIG 456
ELGLLIFFLFIGV+LFSSAVYFAE D S F+SIP++FWWAVVTMTTVGYGDM PVT+G
Sbjct: 311 ELGLLIFFLFIGVVLFSSAVYFAEVDRVDSHFTSIPESFWWAVVTMTTVGYGDMAPVTVG 370
Query: 457 GKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQSQYMHV 502
GKIVGSLCAIAGVLTI+LPVPVIVSNF+YFYHRETEGEE + HV
Sbjct: 371 GKIVGSLCAIAGVLTISLPVPVIVSNFSYFYHRETEGEEAGMFSHV 416
>gi|5031819 potassium voltage-gated channel, shaker-related
subfamily, member 10 [Homo sapiens]
Length = 511
Score = 577 bits (1487), Expect = e-164
Identities = 286/394 (72%), Positives = 332/394 (84%), Gaps = 7/394 (1%)
Query: 104 ERVVINISGLRFETQLKTLCQFPETLLGDPKRRMRYFDPLRNEYFFDRNRPSFDAILYYY 163
+RV+INI+GLRFETQL+TL QFPETLLGD ++RM++FD +RNEYFFDRNRPSFD ILYYY
Sbjct: 86 QRVIINIAGLRFETQLRTLSQFPETLLGDREKRMQFFDSMRNEYFFDRNRPSFDGILYYY 145
Query: 164 QSGGRIRRPVNVPIDIFSEEIRFYQLGEEAMEKFREDEGFLREEERPLPRRDFQRQVWLL 223
QSGG+IRRP NVPIDIF++EI FY+LG EAM++FREDEGF+++ E LP D RQ WLL
Sbjct: 146 QSGGKIRRPANVPIDIFADEISFYELGSEAMDQFREDEGFIKDPETLLPTNDIHRQFWLL 205
Query: 224 FEYPESSGPARGIAIVSVLVILISIVIFCLETLPEFRDEKDYPASTSQDSFEAAGNSTSG 283
FEYPESS AR +A+VSVLV++ISI IFCLETLPEFR++++ + + S
Sbjct: 206 FEYPESSSAARAVAVVSVLVVVISITIFCLETLPEFREDRELKVVRDPNL------NMSK 259
Query: 284 SRAGASSFSDPFFVVETLCIIWFSFELLVRFFACPSKATFSRNIMNLIDIVAIIPYFITL 343
+ + F+DPFF+VE+ CI+WF+FEL++RF CPSK F RNIMN+IDI++IIPYF TL
Sbjct: 260 TVLSQTMFTDPFFMVESTCIVWFTFELVLRFVVCPSKTDFFRNIMNIIDIISIIPYFATL 319
Query: 344 GTELA-ERQGNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLI 402
TEL E + + QQ MSLAILR+IRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLI
Sbjct: 320 ITELVQETEPSAQQNMSLAILRIIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLI 379
Query: 403 FFLFIGVILFSSAVYFAEADDPTSGFSSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGS 462
FFLFIGVILFSSAVYFAE D+P S FSSIPD FWWAVVTMTTVGYGDM P T GGKIVG+
Sbjct: 380 FFLFIGVILFSSAVYFAEVDEPESHFSSIPDGFWWAVVTMTTVGYGDMCPTTPGGKIVGT 439
Query: 463 LCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQ 496
LCAIAGVLTIALPVPVIVSNFNYFYHRETE EE+
Sbjct: 440 LCAIAGVLTIALPVPVIVSNFNYFYHRETENEEK 473
>gi|27436981 potassium voltage-gated channel, Shal-related
subfamily, member 1 [Homo sapiens]
Length = 647
Score = 278 bits (711), Expect = 1e-74
Identities = 181/494 (36%), Positives = 269/494 (54%), Gaps = 65/494 (13%)
Query: 87 EPLPPSLPAAGEQDCCGERV-VINISGLRFETQLKTLCQFPETLLGDPKRRMRYFDPLRN 145
+PLPP A G + G+ V V+N+SG RFET TL ++P+TLLG ++ ++D
Sbjct: 25 QPLPP---APGVKASRGDEVLVVNVSGRRFETWKNTLDRYPDTLLGSSEKEF-FYDADSG 80
Query: 146 EYFFDRNRPSFDAILYYYQSGGRIRRPVNVPIDIFSEEIRFYQL-----GEEAMEKFR-- 198
EYFFDR+ F +L +Y++G R+ P I F EE+ FY L G+ +E++R
Sbjct: 81 EYFFDRDPDMFRHVLNFYRTG-RLHCPRQECIQAFDEELAFYGLVPELVGDCCLEEYRDR 139
Query: 199 ---------EDEGFLREEERP-LPRRDFQRQ-VWLLFEYPESSGPARGIAIVSVLVILIS 247
EDE + + P LP RQ +W FE P +S A V+ I +S
Sbjct: 140 KKENAERLAEDEEAEQAGDGPALPAGSSLRQRLWRAFENPHTSTAALVFYYVTGFFIAVS 199
Query: 248 IVIFCLETLPEFRDEKDYPASTSQDSFEAAGNSTSGSRAGASSFSDPFFVVETLCIIWFS 307
++ +ET+P + +S + F FF ++T C++ F+
Sbjct: 200 VIANVVETIP----------------CRGSARRSSREQPCGERFPQAFFCMDTACVLIFT 243
Query: 308 FELLVRFFACPSKATFSRNIMNLIDIVAIIPYFITLGTELAERQGNGQQAMSLAILRVIR 367
E L+R FA PS+ F R++M+LID+VAI+PY+I L L + + A +R
Sbjct: 244 GEYLLRLFAAPSRCRFLRSVMSLIDVVAILPYYIGL---LVPKNDDVSGAFV-----TLR 295
Query: 368 LVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADDPTSG 427
+ RVFRIFK SRHS+GL+ILG TLK+ ELG L+F L + +I+F++ +++AE +
Sbjct: 296 VFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGTNKTN 355
Query: 428 FSSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFY 487
F+SIP AFW+ +VTMTT+GYGDM P TI GKI GS+C+++GVL IALPVPVIVSNF+ Y
Sbjct: 356 FTSIPAAFWYTIVTMTTLGYGDMVPSTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIY 415
Query: 488 HRETEGEEQSQYMHVGSCQHLSSSAEELRKARSNSTLSKSEYMVIEEGGMNHSAFPQTPF 547
H+ +++ V +R A+S +T + +Y + GG+ S
Sbjct: 416 HQNQRADKRRAQQKV--------RLARIRLAKSGTTNAFLQYK--QNGGLEDSG------ 459
Query: 548 KTGNSTATCTTNNN 561
+G A C N +
Sbjct: 460 -SGEEQALCVRNRS 472
>gi|27436974 potassium voltage-gated channel, Shab-related
subfamily, member 2 [Homo sapiens]
Length = 911
Score = 269 bits (687), Expect = 6e-72
Identities = 162/437 (37%), Positives = 245/437 (56%), Gaps = 54/437 (12%)
Query: 89 LPPSLPAAGEQDCCGERVVINISGLRFETQLKTLCQFPETLLGDPKRRMRYFDPLR---- 144
LPP C RV IN+ GL E +TL + P T LG + + L
Sbjct: 20 LPPEPVDIIRSKTCSRRVKINVGGLNHEVLWRTLDRLPRTRLGKLRDCNTHESLLEVCDD 79
Query: 145 -----NEYFFDRNRPSFDAILYYYQSGGRIRRPVNVPIDIFSEEI--------------- 184
NEYFFDR+ +F +IL +Y++G ++ + F +E+
Sbjct: 80 YNLNENEYFFDRHPGAFTSILNFYRTG-KLHMMEEMCALSFGQELDYWGIDEIYLESCCQ 138
Query: 185 -RFYQLGEEAMEKFREDEGFLREEERPLPRR----DFQRQVWLLFEYPESSGPARGIAIV 239
R++Q E+ E+ R + +RE E D ++++W L E P SS A+ +AIV
Sbjct: 139 ARYHQKKEQMNEELRREAETMREREGEEFDNTCCPDKRKKLWDLLEKPNSSVAAKILAIV 198
Query: 240 SVLVILISIVIFCLETLPEFRDEKDYPASTSQDSFEAAGNSTSGSRAGASSFSDPFFVVE 299
S+L I++S + L TLPE ++ ++ G + + VE
Sbjct: 199 SILFIVLSTIALSLNTLPELQETDEF---------------------GQLNDNRQLAHVE 237
Query: 300 TLCIIWFSFELLVRFFACPSKATFSRNIMNLIDIVAIIPYFITLGTELAERQGNGQQAMS 359
+CI WF+ E L+RF + P+K F + +N+ID++AI+PY++T+ L E + Q +
Sbjct: 238 AVCIAWFTMEYLLRFLSSPNKWKFFKGPLNVIDLLAILPYYVTIF--LTESNKSVLQFQN 295
Query: 360 LA-ILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYF 418
+ ++++ R++R+ RI KL+RHS GLQ LG TL+ S ELGLLI FL +G+++FSS V+F
Sbjct: 296 VRRVVQIFRIMRILRILKLARHSTGLQSLGFTLRRSYNELGLLILFLAMGIMIFSSLVFF 355
Query: 419 AEADDPTSGFSSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPV 478
AE D+ + F+SIP +FWWA +TMTTVGYGD++P T+ GKIVG LC IAGVL IALP+P+
Sbjct: 356 AEKDEDATKFTSIPASFWWATITMTTVGYGDIYPKTLLGKIVGGLCCIAGVLVIALPIPI 415
Query: 479 IVSNFNYFYHRETEGEE 495
IV+NF+ FY + E+
Sbjct: 416 IVNNFSEFYKEQKRQEK 432
>gi|4826784 potassium voltage-gated channel, Shab-related subfamily,
member 1 [Homo sapiens]
Length = 858
Score = 268 bits (686), Expect = 8e-72
Identities = 163/437 (37%), Positives = 243/437 (55%), Gaps = 54/437 (12%)
Query: 89 LPPSLPAAGEQDCCGERVVINISGLRFETQLKTLCQFPETLLGDPKRRMRYFDPLR---- 144
LPP C RV +N+ GL E +TL + P T LG + + L
Sbjct: 16 LPPEPMEIVRSKACSRRVRLNVGGLAHEVLWRTLDRLPRTRLGKLRDCNTHDSLLEVCDD 75
Query: 145 -----NEYFFDRNRPSFDAILYYYQSGGRIRRPVNVPIDIFSEEI--------------- 184
NEYFFDR+ +F +IL +Y++G R+ + FS+E+
Sbjct: 76 YSLDDNEYFFDRHPGAFTSILNFYRTG-RLHMMEEMCALSFSQELDYWGIDEIYLESCCQ 134
Query: 185 -RFYQLGEEAMEKFREDEGFLREEERP----LPRRDFQRQVWLLFEYPESSGPARGIAIV 239
R++Q E+ E+ + + LRE E + ++++W L E P SS A+ +AI+
Sbjct: 135 ARYHQKKEQMNEELKREAETLREREGEEFDNTCCAEKRKKLWDLLEKPNSSVAAKILAII 194
Query: 240 SVLVILISIVIFCLETLPEFRDEKDYPASTSQDSFEAAGNSTSGSRAGASSFSDPFFVVE 299
S++ I++S + L TLPE + S + G ST + VE
Sbjct: 195 SIMFIVLSTIALSLNTLPELQ------------SLDEFGQSTDNPQLAH---------VE 233
Query: 300 TLCIIWFSFELLVRFFACPSKATFSRNIMNLIDIVAIIPYFITLGTELAERQGNGQQAMS 359
+CI WF+ E L+RF + P K F + +N ID++AI+PY++T+ L E + Q +
Sbjct: 234 AVCIAWFTMEYLLRFLSSPKKWKFFKGPLNAIDLLAILPYYVTIF--LTESNKSVLQFQN 291
Query: 360 LA-ILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYF 418
+ ++++ R++R+ RI KL+RHS GLQ LG TL+ S ELGLLI FL +G+++FSS V+F
Sbjct: 292 VRRVVQIFRIMRILRILKLARHSTGLQSLGFTLRRSYNELGLLILFLAMGIMIFSSLVFF 351
Query: 419 AEADDPTSGFSSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPV 478
AE D+ + F SIP +FWWA +TMTTVGYGD++P T+ GKIVG LC IAGVL IALP+P+
Sbjct: 352 AEKDEDDTKFKSIPASFWWATITMTTVGYGDIYPKTLLGKIVGGLCCIAGVLVIALPIPI 411
Query: 479 IVSNFNYFYHRETEGEE 495
IV+NF+ FY + E+
Sbjct: 412 IVNNFSEFYKEQKRQEK 428
>gi|4826786 Shaw-related voltage-gated potassium channel protein 1
isoform B [Homo sapiens]
Length = 511
Score = 265 bits (678), Expect = 7e-71
Identities = 167/448 (37%), Positives = 239/448 (53%), Gaps = 76/448 (16%)
Query: 104 ERVVINISGLRFETQLKTLCQFPETLLG---DPKRRMRY-FDPLRNEYFFDRNRPSFDAI 159
ER+VIN+ G R +T TL P T L +P + +DP +E+FFDR+ F I
Sbjct: 8 ERIVINVGGTRHQTYRSTLRTLPGTRLAWLAEPDAHSHFDYDPRADEFFFDRHPGVFAHI 67
Query: 160 LYYYQSGGRIRRPVNVPIDIFSEEIRFYQL------------------GEEAMEKFRE-- 199
L YY++G ++ P +V ++ EE+ F+ + EEA++ F
Sbjct: 68 LNYYRTG-KLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDSFGGAP 126
Query: 200 --------------DEGFLREEERPLPR---------------RDFQRQVWLLFEYPESS 230
D G +E R R +Q ++W LFE P SS
Sbjct: 127 LDNSADDADADGPGDSGDGEDELEMTKRLALSDSPDGRPGGFWRRWQPRIWALFEDPYSS 186
Query: 231 GPARGIAIVSVLVILISIVIFCLETLPEFRDEKDYPASTSQDSFEAAGNSTSGSRAGASS 290
AR +A S+ IL+SI FCLET F ++ E N T +
Sbjct: 187 RYARYVAFASLFFILVSITTFCLETHERFNP------IVNKTEIENVRNGTQVRYYREAE 240
Query: 291 FSDPFFVVETLCIIWFSFELLVRFFACPSKATFSRNIMNLIDIVAIIPYFITLGTELAER 350
+E +C++WF+FE L+R CP+K F +N +N+ID VAI+P+++ +G
Sbjct: 241 TEAFLTYIEGVCVVWFTFEFLMRVIFCPNKVEFIKNSLNIIDFVAILPFYLEVGLS---- 296
Query: 351 QGNGQQAMS--LAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIG 408
G +A L LRV+R VR+ RIFKL+RH GL++LG TL+AS E LLI FL +G
Sbjct: 297 -GLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALG 355
Query: 409 VILFSSAVYFAEA-----DDPTSG----FSSIPDAFWWAVVTMTTVGYGDMHPVTIGGKI 459
V++F++ +Y+AE +DP++ F +IP FWWAVVTMTT+GYGDM+P T G +
Sbjct: 356 VLIFATMIYYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGML 415
Query: 460 VGSLCAIAGVLTIALPVPVIVSNFNYFY 487
VG+LCA+AGVLTIA+PVPVIV+NF +Y
Sbjct: 416 VGALCALAGVLTIAMPVPVIVNNFGMYY 443
>gi|163792201 Shaw-related voltage-gated potassium channel protein 1
isoform A [Homo sapiens]
Length = 585
Score = 265 bits (678), Expect = 7e-71
Identities = 167/448 (37%), Positives = 239/448 (53%), Gaps = 76/448 (16%)
Query: 104 ERVVINISGLRFETQLKTLCQFPETLLG---DPKRRMRY-FDPLRNEYFFDRNRPSFDAI 159
ER+VIN+ G R +T TL P T L +P + +DP +E+FFDR+ F I
Sbjct: 8 ERIVINVGGTRHQTYRSTLRTLPGTRLAWLAEPDAHSHFDYDPRADEFFFDRHPGVFAHI 67
Query: 160 LYYYQSGGRIRRPVNVPIDIFSEEIRFYQL------------------GEEAMEKFRE-- 199
L YY++G ++ P +V ++ EE+ F+ + EEA++ F
Sbjct: 68 LNYYRTG-KLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDSFGGAP 126
Query: 200 --------------DEGFLREEERPLPR---------------RDFQRQVWLLFEYPESS 230
D G +E R R +Q ++W LFE P SS
Sbjct: 127 LDNSADDADADGPGDSGDGEDELEMTKRLALSDSPDGRPGGFWRRWQPRIWALFEDPYSS 186
Query: 231 GPARGIAIVSVLVILISIVIFCLETLPEFRDEKDYPASTSQDSFEAAGNSTSGSRAGASS 290
AR +A S+ IL+SI FCLET F ++ E N T +
Sbjct: 187 RYARYVAFASLFFILVSITTFCLETHERFNP------IVNKTEIENVRNGTQVRYYREAE 240
Query: 291 FSDPFFVVETLCIIWFSFELLVRFFACPSKATFSRNIMNLIDIVAIIPYFITLGTELAER 350
+E +C++WF+FE L+R CP+K F +N +N+ID VAI+P+++ +G
Sbjct: 241 TEAFLTYIEGVCVVWFTFEFLMRVIFCPNKVEFIKNSLNIIDFVAILPFYLEVGLS---- 296
Query: 351 QGNGQQAMS--LAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIG 408
G +A L LRV+R VR+ RIFKL+RH GL++LG TL+AS E LLI FL +G
Sbjct: 297 -GLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALG 355
Query: 409 VILFSSAVYFAEA-----DDPTSG----FSSIPDAFWWAVVTMTTVGYGDMHPVTIGGKI 459
V++F++ +Y+AE +DP++ F +IP FWWAVVTMTT+GYGDM+P T G +
Sbjct: 356 VLIFATMIYYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGML 415
Query: 460 VGSLCAIAGVLTIALPVPVIVSNFNYFY 487
VG+LCA+AGVLTIA+PVPVIV+NF +Y
Sbjct: 416 VGALCALAGVLTIAMPVPVIVNNFGMYY 443
>gi|27436984 potassium voltage-gated channel, Shal-related
subfamily, member 3 isoform 1 [Homo sapiens]
Length = 655
Score = 263 bits (673), Expect = 2e-70
Identities = 163/471 (34%), Positives = 256/471 (54%), Gaps = 54/471 (11%)
Query: 90 PPSLPAAGEQDCCGERVVINISGLRFETQLKTLCQFPETLLGDPKRRMRYFDPLRNEYFF 149
P L A + E +V+N+SG RF+T TL ++P+TLLG ++ +F+ EYFF
Sbjct: 26 PMPLAPADKNKRQDELIVLNVSGRRFQTWRTTLERYPDTLLGSTEKEF-FFNEDTKEYFF 84
Query: 150 DRNRPSFDAILYYYQSGGRIRRPVNVPIDIFSEEIRFYQL-----GEEAMEKFRE----- 199
DR+ F +L +Y++G ++ P I + +E+ FY + G+ E++++
Sbjct: 85 DRDPEVFRCVLNFYRTG-KLHYPRYECISAYDDELAFYGILPEIIGDCCYEEYKDRKREN 143
Query: 200 -----DEGFLREEERPLPRRDFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLE 254
D+ + +P F++ +W FE P +S A V+ I +S++ +E
Sbjct: 144 AERLMDDNDSENNQESMPSLSFRQTMWRAFENPHTSTLALVFYYVTGFFIAVSVITNVVE 203
Query: 255 TLPEFRDEKDYPASTSQDSFEAAGNSTSGSRAGASSFSDPFFVVETLCIIWFSFELLVRF 314
T+P T S E G R +S FF ++T C++ F+ E L+R
Sbjct: 204 TVP---------CGTVPGSKELP----CGER-----YSVAFFCLDTACVMIFTVEYLLRL 245
Query: 315 FACPSKATFSRNIMNLIDIVAIIPYFITLGTELAERQGNGQQAMSLAILRVIRLVRVFRI 374
FA PS+ F R++M++ID+VAI+PY+I L N + + +R+ RVFRI
Sbjct: 246 FAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMT------NNEDVSGAFV--TLRVFRVFRI 297
Query: 375 FKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADDPTSGFSSIPDA 434
FK SRHS+GL+ILG TLK+ ELG L+F L + +I+F++ +++AE S F+SIP +
Sbjct: 298 FKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPAS 357
Query: 435 FWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGE 494
FW+ +VTMTT+GYGDM P TI GKI GS+C+++GVL IALPVPVIVSNF+ YH+ +
Sbjct: 358 FWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRAD 417
Query: 495 EQSQYMHVGSCQHLSSSAEELRKARSNSTLSKSEYMVIEEGGMNHSAFPQT 545
++ + L + R T S + Y+ + G+ + A T
Sbjct: 418 KRR-----------AQKKARLARIRVAKTGSSNAYLHSKRNGLLNEALELT 457
>gi|27436986 potassium voltage-gated channel, Shal-related
subfamily, member 3 isoform 2 [Homo sapiens]
Length = 636
Score = 263 bits (673), Expect = 2e-70
Identities = 163/471 (34%), Positives = 256/471 (54%), Gaps = 54/471 (11%)
Query: 90 PPSLPAAGEQDCCGERVVINISGLRFETQLKTLCQFPETLLGDPKRRMRYFDPLRNEYFF 149
P L A + E +V+N+SG RF+T TL ++P+TLLG ++ +F+ EYFF
Sbjct: 26 PMPLAPADKNKRQDELIVLNVSGRRFQTWRTTLERYPDTLLGSTEKEF-FFNEDTKEYFF 84
Query: 150 DRNRPSFDAILYYYQSGGRIRRPVNVPIDIFSEEIRFYQL-----GEEAMEKFRE----- 199
DR+ F +L +Y++G ++ P I + +E+ FY + G+ E++++
Sbjct: 85 DRDPEVFRCVLNFYRTG-KLHYPRYECISAYDDELAFYGILPEIIGDCCYEEYKDRKREN 143
Query: 200 -----DEGFLREEERPLPRRDFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLE 254
D+ + +P F++ +W FE P +S A V+ I +S++ +E
Sbjct: 144 AERLMDDNDSENNQESMPSLSFRQTMWRAFENPHTSTLALVFYYVTGFFIAVSVITNVVE 203
Query: 255 TLPEFRDEKDYPASTSQDSFEAAGNSTSGSRAGASSFSDPFFVVETLCIIWFSFELLVRF 314
T+P T S E G R +S FF ++T C++ F+ E L+R
Sbjct: 204 TVP---------CGTVPGSKELP----CGER-----YSVAFFCLDTACVMIFTVEYLLRL 245
Query: 315 FACPSKATFSRNIMNLIDIVAIIPYFITLGTELAERQGNGQQAMSLAILRVIRLVRVFRI 374
FA PS+ F R++M++ID+VAI+PY+I L N + + +R+ RVFRI
Sbjct: 246 FAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMT------NNEDVSGAFV--TLRVFRVFRI 297
Query: 375 FKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADDPTSGFSSIPDA 434
FK SRHS+GL+ILG TLK+ ELG L+F L + +I+F++ +++AE S F+SIP +
Sbjct: 298 FKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPAS 357
Query: 435 FWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGE 494
FW+ +VTMTT+GYGDM P TI GKI GS+C+++GVL IALPVPVIVSNF+ YH+ +
Sbjct: 358 FWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRAD 417
Query: 495 EQSQYMHVGSCQHLSSSAEELRKARSNSTLSKSEYMVIEEGGMNHSAFPQT 545
++ + L + R T S + Y+ + G+ + A T
Sbjct: 418 KRR-----------AQKKARLARIRVAKTGSSNAYLHSKRNGLLNEALELT 457
>gi|9789987 potassium voltage-gated channel, Shal-related subfamily,
member 2 [Homo sapiens]
Length = 630
Score = 262 bits (669), Expect = 7e-70
Identities = 164/468 (35%), Positives = 257/468 (54%), Gaps = 61/468 (13%)
Query: 88 PLPPSLPAAGEQDCCGERVVINISGLRFETQLKTLCQFPETLLGDPKRRMRYFDPLRNEY 147
P PP QD +V+N+SG RF+T TL ++P+TLLG +R ++ P +Y
Sbjct: 28 PAPPRQERKRTQDAL---IVLNVSGTRFQTWQDTLERYPDTLLGSSERDF-FYHPETQQY 83
Query: 148 FFDRNRPSFDAILYYYQSGGRIRRPVNVPIDIFSEEIRFYQL---------GEEAMEKFR 198
FFDR+ F IL +Y++G ++ P + I + EE+ F+ L EE ++ R
Sbjct: 84 FFDRDPDIFRHILNFYRTG-KLHYPRHECISAYDEELAFFGLIPEIIGDCCYEEYKDRRR 142
Query: 199 EDEGFLREE-------ERPLPRRDFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIF 251
E+ L+++ E LP +++VW FE P +S A V+ I +S++
Sbjct: 143 ENAERLQDDADTDTAGESALPTMTARQRVWRAFENPHTSTMALVFYYVTGFFIAVSVIAN 202
Query: 252 CLETLPEFRDEKDYPASTSQDSFEAAGNSTSGSRA--GASSFSDPFFVVETLCIIWFSFE 309
+ET+P G+S + ++ FF ++T C++ F+ E
Sbjct: 203 VVETVP-------------------CGSSPGHIKELPCGERYAVAFFCLDTACVMIFTVE 243
Query: 310 LLVRFFACPSKATFSRNIMNLIDIVAIIPYFITLGTELAERQGNGQQAMSLAILRVIRLV 369
L+R A PS+ F R++M++ID+VAI+PY+I G + + + ++L R+
Sbjct: 244 YLLRLAAAPSRYRFVRSVMSIIDVVAILPYYI--GLVMTDNEDVSGAFVTL------RVF 295
Query: 370 RVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADDPTSGFS 429
RVFRIFK SRHS+GL+ILG TLK+ ELG L+F L + +I+F++ +++AE S F+
Sbjct: 296 RVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFT 355
Query: 430 SIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHR 489
SIP AFW+ +VTMTT+GYGDM P TI GKI GS+C+++GVL IALPVPVIVSNF+ YH+
Sbjct: 356 SIPAAFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQ 415
Query: 490 ETEGEEQSQYMHVGSCQHLSSSAEELRKARSNSTLSKSEYMVIEEGGM 537
+++ + L + R+ + S + YM + G+
Sbjct: 416 NQRADKRR-----------AQKKARLARIRAAKSGSANAYMQSKRNGL 452
>gi|88758576 Shaw-related voltage-gated potassium channel protein 4
isoform c [Homo sapiens]
Length = 626
Score = 255 bits (651), Expect = 9e-68
Identities = 174/476 (36%), Positives = 240/476 (50%), Gaps = 93/476 (19%)
Query: 90 PPSLPAAGEQDCCGE---RVVINISGLRFETQLKTLCQFPETLLG---DPKRRMRYFDPL 143
PPS E+ GE +++IN+ G R ET TL P T L DP R P
Sbjct: 19 PPSKTCLKEEMAKGEASEKIIINVGGTRHETYRSTLRTLPGTRLAWLADPDGGGR---PE 75
Query: 144 RN---------------EYFFDRNRPSFDAILYYYQSGGRIRRPVNVPIDIFSEEIRFYQ 188
+ E+FFDR+ F +L YY++G ++ P +V +F EE+ F+
Sbjct: 76 TDGGGVGSSGSSGGGGCEFFFDRHPGVFAYVLNYYRTG-KLHCPADVCGPLFEEELTFWG 134
Query: 189 L------------------GEEAMEKFRE-----------DEGFLREEERPLPR------ 213
+ EEA++ F DE E E L R
Sbjct: 135 IDETDVEPCCWMTYRQHRDAEEALDIFESPDGGGSGAGPSDEAGDDERELALQRLGPHEG 194
Query: 214 -----------RDFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPEFRDE 262
R +Q ++W LFE P SS AR +A S+ IL+SI FCLET F +
Sbjct: 195 GAGHGAGSGGCRGWQPRMWALFEDPYSSRAARVVAFASLFFILVSITTFCLETHEAFNID 254
Query: 263 KDYPASTSQDSFEAAGNSTSGSRAGASSFSDPFFVVETLCIIWFSFELLVRFFACPSKAT 322
++ GN TS +E +C++WF+ E LVR CP
Sbjct: 255 RNVT------EILRVGNITSVHFRREVETEPILTYIEGVCVLWFTLEFLVRIVCCPDTLD 308
Query: 323 FSRNIMNLIDIVAIIPYFITLGTELAERQGNGQQAMS--LAILRVIRLVRVFRIFKLSRH 380
F +N++N+ID VAI+P+++ +G G +A L LRV+R VR+ RIFKL+RH
Sbjct: 309 FVKNLLNIIDFVAILPFYLEVGLS-----GLSSKAARDVLGFLRVVRFVRILRIFKLTRH 363
Query: 381 SKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEA-----DDPTSG----FSSI 431
GL++LG TL+AS E LLI FL +GV++F++ +Y+AE DP F +I
Sbjct: 364 FVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGARPSDPRGNDHTDFKNI 423
Query: 432 PDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFY 487
P FWWAVVTMTT+GYGDM+P T G +VG+LCA+AGVLTIA+PVPVIV+NF +Y
Sbjct: 424 PIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYY 479
>gi|24497462 Shaw-related voltage-gated potassium channel protein 4
isoform a [Homo sapiens]
Length = 635
Score = 255 bits (651), Expect = 9e-68
Identities = 174/476 (36%), Positives = 240/476 (50%), Gaps = 93/476 (19%)
Query: 90 PPSLPAAGEQDCCGE---RVVINISGLRFETQLKTLCQFPETLLG---DPKRRMRYFDPL 143
PPS E+ GE +++IN+ G R ET TL P T L DP R P
Sbjct: 19 PPSKTCLKEEMAKGEASEKIIINVGGTRHETYRSTLRTLPGTRLAWLADPDGGGR---PE 75
Query: 144 RN---------------EYFFDRNRPSFDAILYYYQSGGRIRRPVNVPIDIFSEEIRFYQ 188
+ E+FFDR+ F +L YY++G ++ P +V +F EE+ F+
Sbjct: 76 TDGGGVGSSGSSGGGGCEFFFDRHPGVFAYVLNYYRTG-KLHCPADVCGPLFEEELTFWG 134
Query: 189 L------------------GEEAMEKFRE-----------DEGFLREEERPLPR------ 213
+ EEA++ F DE E E L R
Sbjct: 135 IDETDVEPCCWMTYRQHRDAEEALDIFESPDGGGSGAGPSDEAGDDERELALQRLGPHEG 194
Query: 214 -----------RDFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPEFRDE 262
R +Q ++W LFE P SS AR +A S+ IL+SI FCLET F +
Sbjct: 195 GAGHGAGSGGCRGWQPRMWALFEDPYSSRAARVVAFASLFFILVSITTFCLETHEAFNID 254
Query: 263 KDYPASTSQDSFEAAGNSTSGSRAGASSFSDPFFVVETLCIIWFSFELLVRFFACPSKAT 322
++ GN TS +E +C++WF+ E LVR CP
Sbjct: 255 RNVT------EILRVGNITSVHFRREVETEPILTYIEGVCVLWFTLEFLVRIVCCPDTLD 308
Query: 323 FSRNIMNLIDIVAIIPYFITLGTELAERQGNGQQAMS--LAILRVIRLVRVFRIFKLSRH 380
F +N++N+ID VAI+P+++ +G G +A L LRV+R VR+ RIFKL+RH
Sbjct: 309 FVKNLLNIIDFVAILPFYLEVGLS-----GLSSKAARDVLGFLRVVRFVRILRIFKLTRH 363
Query: 381 SKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEA-----DDPTSG----FSSI 431
GL++LG TL+AS E LLI FL +GV++F++ +Y+AE DP F +I
Sbjct: 364 FVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGARPSDPRGNDHTDFKNI 423
Query: 432 PDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFY 487
P FWWAVVTMTT+GYGDM+P T G +VG+LCA+AGVLTIA+PVPVIV+NF +Y
Sbjct: 424 PIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYY 479
>gi|24497464 Shaw-related voltage-gated potassium channel protein 4
isoform b [Homo sapiens]
Length = 582
Score = 255 bits (651), Expect = 9e-68
Identities = 174/476 (36%), Positives = 240/476 (50%), Gaps = 93/476 (19%)
Query: 90 PPSLPAAGEQDCCGE---RVVINISGLRFETQLKTLCQFPETLLG---DPKRRMRYFDPL 143
PPS E+ GE +++IN+ G R ET TL P T L DP R P
Sbjct: 19 PPSKTCLKEEMAKGEASEKIIINVGGTRHETYRSTLRTLPGTRLAWLADPDGGGR---PE 75
Query: 144 RN---------------EYFFDRNRPSFDAILYYYQSGGRIRRPVNVPIDIFSEEIRFYQ 188
+ E+FFDR+ F +L YY++G ++ P +V +F EE+ F+
Sbjct: 76 TDGGGVGSSGSSGGGGCEFFFDRHPGVFAYVLNYYRTG-KLHCPADVCGPLFEEELTFWG 134
Query: 189 L------------------GEEAMEKFRE-----------DEGFLREEERPLPR------ 213
+ EEA++ F DE E E L R
Sbjct: 135 IDETDVEPCCWMTYRQHRDAEEALDIFESPDGGGSGAGPSDEAGDDERELALQRLGPHEG 194
Query: 214 -----------RDFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPEFRDE 262
R +Q ++W LFE P SS AR +A S+ IL+SI FCLET F +
Sbjct: 195 GAGHGAGSGGCRGWQPRMWALFEDPYSSRAARVVAFASLFFILVSITTFCLETHEAFNID 254
Query: 263 KDYPASTSQDSFEAAGNSTSGSRAGASSFSDPFFVVETLCIIWFSFELLVRFFACPSKAT 322
++ GN TS +E +C++WF+ E LVR CP
Sbjct: 255 RNVT------EILRVGNITSVHFRREVETEPILTYIEGVCVLWFTLEFLVRIVCCPDTLD 308
Query: 323 FSRNIMNLIDIVAIIPYFITLGTELAERQGNGQQAMS--LAILRVIRLVRVFRIFKLSRH 380
F +N++N+ID VAI+P+++ +G G +A L LRV+R VR+ RIFKL+RH
Sbjct: 309 FVKNLLNIIDFVAILPFYLEVGLS-----GLSSKAARDVLGFLRVVRFVRILRIFKLTRH 363
Query: 381 SKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEA-----DDPTSG----FSSI 431
GL++LG TL+AS E LLI FL +GV++F++ +Y+AE DP F +I
Sbjct: 364 FVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGARPSDPRGNDHTDFKNI 423
Query: 432 PDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFY 487
P FWWAVVTMTT+GYGDM+P T G +VG+LCA+AGVLTIA+PVPVIV+NF +Y
Sbjct: 424 PIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYY 479
>gi|21217561 Shaw-related voltage-gated potassium channel protein 2
isoform KV3.2a [Homo sapiens]
Length = 613
Score = 245 bits (626), Expect = 7e-65
Identities = 155/394 (39%), Positives = 215/394 (54%), Gaps = 66/394 (16%)
Query: 146 EYFFDRNRPSFDAILYYYQSGGRIRRPVNVPIDIFSEEIRFYQL---------------- 189
E+FFDR+ F +L YY++G ++ P +V +F EE+ F+ +
Sbjct: 101 EFFFDRHPGVFAYVLNYYRTG-KLHCPADVCGPLFEEELAFWGIDETDVEPCCWMTYRQH 159
Query: 190 --GEEAMEKFR----------------------EDEGFLREEERPLPR-RDFQRQVWLLF 224
EEA++ F ED L + R R Q ++W LF
Sbjct: 160 RDAEEALDIFETPDLIGGDPGDDEDLAAKRLGIEDAAGLGGPDGKSGRWRRLQPRMWALF 219
Query: 225 EYPESSGPARGIAIVSVLVILISIVIFCLETLPEFRDEKDYPASTSQDSFEAAGNSTSGS 284
E P SS AR IA S+ IL+SI FCLET F K+ E N TS
Sbjct: 220 EDPYSSRAARFIAFASLFFILVSITTFCLETHEAFNIVKN--------KTEPVINGTSVV 271
Query: 285 RAGASSFSDPFFVVETLCIIWFSFELLVRFFACPSKATFSRNIMNLIDIVAIIPYFITLG 344
VE +C++WF+FE LVR P+K F +N++N+ID VAI+P+++ +G
Sbjct: 272 LQYEIETDPALTYVEGVCVVWFTFEFLVRIVFSPNKLEFIKNLLNIIDFVAILPFYLEVG 331
Query: 345 TELAERQGNGQQAMS--LAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLI 402
G +A L LRV+R VR+ RIFKL+RH GL++LG TL+AS E LLI
Sbjct: 332 LS-----GLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLI 386
Query: 403 FFLFIGVILFSSAVYFAEA-----DDPTSG----FSSIPDAFWWAVVTMTTVGYGDMHPV 453
FL +GV++F++ +Y+AE +DP++ F +IP FWWAVVTMTT+GYGDM+P
Sbjct: 387 IFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPIGFWWAVVTMTTLGYGDMYPQ 446
Query: 454 TIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFY 487
T G +VG+LCA+AGVLTIA+PVPVIV+NF +Y
Sbjct: 447 TWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYY 480
>gi|21217563 Shaw-related voltage-gated potassium channel protein 2
isoform KV3.2b [Homo sapiens]
Length = 638
Score = 245 bits (626), Expect = 7e-65
Identities = 155/394 (39%), Positives = 215/394 (54%), Gaps = 66/394 (16%)
Query: 146 EYFFDRNRPSFDAILYYYQSGGRIRRPVNVPIDIFSEEIRFYQL---------------- 189
E+FFDR+ F +L YY++G ++ P +V +F EE+ F+ +
Sbjct: 101 EFFFDRHPGVFAYVLNYYRTG-KLHCPADVCGPLFEEELAFWGIDETDVEPCCWMTYRQH 159
Query: 190 --GEEAMEKFR----------------------EDEGFLREEERPLPR-RDFQRQVWLLF 224
EEA++ F ED L + R R Q ++W LF
Sbjct: 160 RDAEEALDIFETPDLIGGDPGDDEDLAAKRLGIEDAAGLGGPDGKSGRWRRLQPRMWALF 219
Query: 225 EYPESSGPARGIAIVSVLVILISIVIFCLETLPEFRDEKDYPASTSQDSFEAAGNSTSGS 284
E P SS AR IA S+ IL+SI FCLET F K+ E N TS
Sbjct: 220 EDPYSSRAARFIAFASLFFILVSITTFCLETHEAFNIVKN--------KTEPVINGTSVV 271
Query: 285 RAGASSFSDPFFVVETLCIIWFSFELLVRFFACPSKATFSRNIMNLIDIVAIIPYFITLG 344
VE +C++WF+FE LVR P+K F +N++N+ID VAI+P+++ +G
Sbjct: 272 LQYEIETDPALTYVEGVCVVWFTFEFLVRIVFSPNKLEFIKNLLNIIDFVAILPFYLEVG 331
Query: 345 TELAERQGNGQQAMS--LAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLI 402
G +A L LRV+R VR+ RIFKL+RH GL++LG TL+AS E LLI
Sbjct: 332 LS-----GLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLI 386
Query: 403 FFLFIGVILFSSAVYFAEA-----DDPTSG----FSSIPDAFWWAVVTMTTVGYGDMHPV 453
FL +GV++F++ +Y+AE +DP++ F +IP FWWAVVTMTT+GYGDM+P
Sbjct: 387 IFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPIGFWWAVVTMTTLGYGDMYPQ 446
Query: 454 TIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFY 487
T G +VG+LCA+AGVLTIA+PVPVIV+NF +Y
Sbjct: 447 TWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYY 480
>gi|24497458 Shaw-related voltage-gated potassium channel protein 2
isoform KV3.2c [Homo sapiens]
Length = 558
Score = 245 bits (626), Expect = 7e-65
Identities = 155/394 (39%), Positives = 215/394 (54%), Gaps = 66/394 (16%)
Query: 146 EYFFDRNRPSFDAILYYYQSGGRIRRPVNVPIDIFSEEIRFYQL---------------- 189
E+FFDR+ F +L YY++G ++ P +V +F EE+ F+ +
Sbjct: 101 EFFFDRHPGVFAYVLNYYRTG-KLHCPADVCGPLFEEELAFWGIDETDVEPCCWMTYRQH 159
Query: 190 --GEEAMEKFR----------------------EDEGFLREEERPLPR-RDFQRQVWLLF 224
EEA++ F ED L + R R Q ++W LF
Sbjct: 160 RDAEEALDIFETPDLIGGDPGDDEDLAAKRLGIEDAAGLGGPDGKSGRWRRLQPRMWALF 219
Query: 225 EYPESSGPARGIAIVSVLVILISIVIFCLETLPEFRDEKDYPASTSQDSFEAAGNSTSGS 284
E P SS AR IA S+ IL+SI FCLET F K+ E N TS
Sbjct: 220 EDPYSSRAARFIAFASLFFILVSITTFCLETHEAFNIVKN--------KTEPVINGTSVV 271
Query: 285 RAGASSFSDPFFVVETLCIIWFSFELLVRFFACPSKATFSRNIMNLIDIVAIIPYFITLG 344
VE +C++WF+FE LVR P+K F +N++N+ID VAI+P+++ +G
Sbjct: 272 LQYEIETDPALTYVEGVCVVWFTFEFLVRIVFSPNKLEFIKNLLNIIDFVAILPFYLEVG 331
Query: 345 TELAERQGNGQQAMS--LAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLI 402
G +A L LRV+R VR+ RIFKL+RH GL++LG TL+AS E LLI
Sbjct: 332 LS-----GLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLI 386
Query: 403 FFLFIGVILFSSAVYFAEA-----DDPTSG----FSSIPDAFWWAVVTMTTVGYGDMHPV 453
FL +GV++F++ +Y+AE +DP++ F +IP FWWAVVTMTT+GYGDM+P
Sbjct: 387 IFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPIGFWWAVVTMTTLGYGDMYPQ 446
Query: 454 TIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFY 487
T G +VG+LCA+AGVLTIA+PVPVIV+NF +Y
Sbjct: 447 TWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYY 480
>gi|13492973 potassium voltage-gated channel delayed-rectifier
protein S1 [Homo sapiens]
Length = 526
Score = 236 bits (601), Expect = 6e-62
Identities = 150/468 (32%), Positives = 247/468 (52%), Gaps = 55/468 (11%)
Query: 104 ERVVINISGLRFETQLKTLCQFPETLLG---------DPKRRMRYFDPLRNEYFFDRNRP 154
E + +N+ G+R + + L +FP T LG +R +D E++FDR+
Sbjct: 50 EALRVNVGGVRRQLSARALARFPGTRLGRLQAAASEEQARRLCDDYDEAAREFYFDRHPG 109
Query: 155 SFDAILYYYQSGGRIRRPVNVPIDIFSEEIRFYQLGEEAM----------------EKFR 198
F ++L++Y++G + + + F +E ++ LGE A+ +
Sbjct: 110 FFLSLLHFYRTG-HLHVLDELCVFAFGQEADYWGLGENALAACCRARYLERRLTQPHAWD 168
Query: 199 EDEGF----------LREEERPLPRRD------FQRQVWLLFEYPESSGPARGIAIVSVL 242
ED + + +R L R +R++WL E P S P++ + VS+
Sbjct: 169 EDSDTPSSVDPCPDEISDVQRELARYGAARCGRLRRRLWLTMENPGYSLPSKLFSCVSIS 228
Query: 243 VILISIVIFCLETLPEFRDEKDYPASTSQDSFEAAGNSTSGSRAGASSFSDPFFV-VETL 301
V+L SI C+ +LPE++ + A + AAG S G R DP +E
Sbjct: 229 VVLASIAAMCIHSLPEYQAREAAAAVAAV----AAGRSPEGVR------DDPVLRRLEYF 278
Query: 302 CIIWFSFELLVRFFACPSKATFSRNIMNLIDIVAIIPYFITLGTELAERQGNGQQAMSLA 361
CI WFSFE+ R PS F + +NLIDIV+++P+++TL +A G++ L
Sbjct: 279 CIAWFSFEVSSRLLLAPSTRNFFCHPLNLIDIVSVLPFYLTLLAGVALGDQGGKEFGHLG 338
Query: 362 -ILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAE 420
+++V RL+R+FR+ KL+RHS GL+ LG TLK S RE+G+L+ +L +GV +FS Y AE
Sbjct: 339 KVVQVFRLMRIFRVLKLARHSTGLRSLGATLKHSYREVGILLLYLAVGVSVFSGVAYTAE 398
Query: 421 ADDPTSGFSSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIV 480
++ GF++IP +WW V+MTTVGYGD+ PVT+ GK+ S C + G+L +ALP+ +I
Sbjct: 399 KEEDV-GFNTIPACWWWGTVSMTTVGYGDVVPVTVAGKLAASGCILGGILVVALPITIIF 457
Query: 481 SNFNYFYHRETEGEEQSQYMHVGSCQHLSSSAEELRKARSNSTLSKSE 528
+ F++FY R+ E + + + L SS + + +A ++ S+
Sbjct: 458 NKFSHFYRRQKALEAAVRNSNHQEFEDLLSSIDGVSEASLETSRETSQ 505
>gi|20070166 potassium voltage-gated channel, subfamily F, member 1
[Homo sapiens]
Length = 494
Score = 234 bits (598), Expect = 1e-61
Identities = 162/482 (33%), Positives = 251/482 (52%), Gaps = 73/482 (15%)
Query: 81 GGCDRYEPLPPSLPAAGEQDCCGERVVINISGLRFETQLKTLCQFPETLLGDPKRRMRY- 139
G +R P P S +A D +V+N+ G+R L Q+PET L + +
Sbjct: 3 GSGERSLPEPGSQSSAASDDI---EIVVNVGGVRQVLYGDLLSQYPETRLAELINCLAGG 59
Query: 140 ----------FDPLRNEYFFDRNRPSFDAILYYYQSGGRIRRPVNVPIDIFSEEIRFYQL 189
+DP + E++FDR+ +F ++ Y G + PI F E+ F+++
Sbjct: 60 YDTIFSLCDDYDPGKREFYFDRDPDAFKCVIEVYYFGEVHMKKGICPI-CFKNEMDFWKV 118
Query: 190 GEEAM---------EKFREDEGFLREEERPLPR----------RDFQRQVWLLFEYPESS 230
+ + EK E E R + L R Q+ VW E PESS
Sbjct: 119 DLKFLDDCCKSHLSEKREELEEIARRVQLILDDLGVDAAEGRWRRCQKCVWKFLEKPESS 178
Query: 231 GPARGIAIVSVLVILISIVIFCLETLPEFRDEKDYPASTSQDSFEAAGNSTSGSRAGASS 290
PAR +A++S L+IL+S V+ C+ T+PE + +A GN R +
Sbjct: 179 CPARVVAVLSFLLILVSSVVMCMGTIPELQ------------VLDAEGN-----RVEHPT 221
Query: 291 FSDPFFVVETLCIIWFSFELLVRFFACPSKATFSRNIMNLIDIVAIIPYFITLG-TELAE 349
+ VET CI WF+ E L+R F+ P+K F+ + MN++D++AI+P++++L T L
Sbjct: 222 LEN----VETACIGWFTLEYLLRLFSSPNKLHFALSFMNIVDVLAILPFYVSLTLTHLGA 277
Query: 350 RQ---GNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLF 406
R N QQA+ + +R++R+ RIFKL+RHS GLQ L LK S +ELGLL+ +L
Sbjct: 278 RMMELTNVQQAV-----QALRIMRIARIFKLARHSSGLQTLTYALKRSFKELGLLLMYLA 332
Query: 407 IGVILFSSAVYFAEADDPTSGFSSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAI 466
+G+ +FS+ Y E P + F SIP +FWWA++TMTTVGYGD++P T GK+ ++ +
Sbjct: 333 VGIFVFSALGYTMEQSHPETLFKSIPQSFWWAIITMTTVGYGDIYPKTTLGKLNAAISFL 392
Query: 467 AGVLTIALPVPVIVSNFNYFYHR----ETEGEEQSQYMHVGSCQHLSSSAEELRKARSNS 522
GV+ IALP+ I++NF +Y++ ET + + + M + SSS E + S S
Sbjct: 393 CGVIAIALPIHPIINNFVRYYNKQRVLETAAKHELELMELN-----SSSGGEGKTGGSRS 447
Query: 523 TL 524
L
Sbjct: 448 DL 449
>gi|25952108 potassium voltage-gated channel delayed-rectifier
protein S3 [Homo sapiens]
Length = 491
Score = 231 bits (588), Expect = 2e-60
Identities = 143/431 (33%), Positives = 220/431 (51%), Gaps = 69/431 (16%)
Query: 104 ERVVINISGLRFETQLKTLCQFPETLLG------DPKRRMRYFDPLR---NEYFFDRNRP 154
E V +N+ G + TL +FP T LG + + D EY+FDRN
Sbjct: 15 ELVNLNVGGFKQSVDQSTLLRFPHTRLGKLLTCHSEEAILELCDDYSVADKEYYFDRNPS 74
Query: 155 SFDAILYYYQSGGRIRRPVNVPIDIFSEEIRFYQLGE----------------EAMEK-- 196
F +L +Y +G ++ + + F +EI ++ + E E EK
Sbjct: 75 LFRYVLNFYYTG-KLHVMEELCVFSFCQEIEYWGINELFIDSCCSNRYQERKEENHEKDW 133
Query: 197 ------------FREDEGFLREEER--PLPRRDFQRQVWLLFEYPESSGPARGIAIVSVL 242
F E F +E E+ L ++++W+ E P A+ IAI S+
Sbjct: 134 DQKSHDVSTDSSFEESSLFEKELEKFDTLRFGQLRKKIWIRMENPAYCLSAKLIAISSLS 193
Query: 243 VILISIVIFCLETLPEFRDEKDYPASTSQDSFEAAGNSTSGSRAGASSFSDPFFV-VETL 301
V+L SIV C+ ++ EF++E DP VE
Sbjct: 194 VVLASIVAMCVHSMSEFQNED-------------------------GEVDDPVLEGVEIA 228
Query: 302 CIIWFSFELLVRFFACPSKATFSRNIMNLIDIVAIIPYFITLGTELAERQGNGQQAMSLA 361
CI WF+ EL VR A P + F +N +N+ID V+IIP++ TL + E + + M
Sbjct: 229 CIAWFTGELAVRLAAAPCQKKFWKNPLNIIDFVSIIPFYATLAVDTKEEESEDIENMG-K 287
Query: 362 ILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEA 421
+++++RL+R+FRI KL+RHS GL+ LG TL+ S E+GLL+ FL +G+ +FS +Y E
Sbjct: 288 VVQILRLMRIFRILKLARHSVGLRSLGATLRHSYHEVGLLLLFLSVGISIFSVLIYSVEK 347
Query: 422 DDPTSGFSSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIVS 481
DD TS +SIP +WWA ++MTTVGYGD HPVT+ GK++ S C I G+L +ALP+ +I +
Sbjct: 348 DDHTSSLTSIPICWWWATISMTTVGYGDTHPVTLAGKLIASTCIICGILVVALPITIIFN 407
Query: 482 NFNYFYHRETE 492
F+ +Y ++ +
Sbjct: 408 KFSKYYQKQKD 418
>gi|24497460 Shaw-related voltage-gated potassium channel protein 3
[Homo sapiens]
Length = 757
Score = 230 bits (586), Expect = 3e-60
Identities = 129/286 (45%), Positives = 178/286 (62%), Gaps = 21/286 (7%)
Query: 214 RDFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPEFRDEKDYPASTSQDS 273
R +Q +VW LFE P SS AR +A S+ ILISI FCLET F + + +
Sbjct: 270 RRWQPRVWALFEDPYSSRAARYVAFASLFFILISITTFCLETHEGFIHISNKTVTQASPI 329
Query: 274 FEAAGNSTSGSRAGASSFSDPFFV-VETLCIIWFSFELLVRFFACPSKATFSRNIMNLID 332
A + + ++PF VE +C++WF+FE L+R CP K F ++ +N+ID
Sbjct: 330 PGAPPENITNVEVE----TEPFLTYVEGVCVVWFTFEFLMRITFCPDKVEFLKSSLNIID 385
Query: 333 IVAIIPYFITLGTELAERQGNGQQAMS--LAILRVIRLVRVFRIFKLSRHSKGLQILGQT 390
VAI+P+++ +G G +A L LRV+R VR+ RIFKL+RH GL++LG T
Sbjct: 386 CVAILPFYLEVGLS-----GLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHT 440
Query: 391 LKASMRELGLLIFFLFIGVILFSSAVYFAE--ADDPT-------SGFSSIPDAFWWAVVT 441
L+AS E LLI FL +GV++F++ +Y+AE DP + F +IP FWWAVVT
Sbjct: 441 LRASTNEFLLLIIFLALGVLIFATMIYYAERIGADPDDILGSNHTYFKNIPIGFWWAVVT 500
Query: 442 MTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFY 487
MTT+GYGDM+P T G +VG+LCA+AGVLTIA+PVPVIV+NF +Y
Sbjct: 501 MTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYY 546
Score = 69.7 bits (169), Expect = 7e-12
Identities = 63/192 (32%), Positives = 86/192 (44%), Gaps = 45/192 (23%)
Query: 10 SPPPPSARHRAHPPQR--PASSGGAHTLVNHGYAEPAAGRELPPDMTVVPGDHLLEPEVA 67
SPPPP PPQ+ PA G A A PA P PGD EP
Sbjct: 30 SPPPPPL-----PPQQQQPAQPGPA--------ASPAG-----PPAPRGPGDRRAEP--C 69
Query: 68 DGGGAPPQGGCGGGGCDRYEPLPPSLPAAGEQDCCGERVVINISGLRFETQLKTLCQFPE 127
G A G GGGG D ++VIN+ G+R ET TL P
Sbjct: 70 PGLPAAAMGRHGGGGGD------------------SGKIVINVGGVRHETYRSTLRTLPG 111
Query: 128 TLLG---DPKRRMRY-FDPLRNEYFFDRNRPSFDAILYYYQSGGRIRRPVNVPIDIFSEE 183
T L +P+ R+ +DP +E+FFDR+ F +L YY++ G++ P +V +F EE
Sbjct: 112 TRLAGLTEPEAAARFDYDPGADEFFFDRHPGVFAYVLNYYRT-GKLHCPADVCGPLFEEE 170
Query: 184 IRFYQLGEEAME 195
+ F+ + E +E
Sbjct: 171 LGFWGIDETDVE 182
>gi|45383011 potassium voltage-gated channel, delayed-rectifier,
subfamily S, member 2 [Homo sapiens]
Length = 477
Score = 227 bits (578), Expect = 3e-59
Identities = 139/428 (32%), Positives = 222/428 (51%), Gaps = 65/428 (15%)
Query: 108 INISGLRFETQLKTLCQFPETLLGDPK---------RRMRYFDPLRNEYFFDRNRPSFDA 158
IN+ G + + TL +FPET LG +D ++ E++FDRN F
Sbjct: 21 INVGGFKRRLRSHTLLRFPETRLGRLLLCHSREAILELCDDYDDVQREFYFDRNPELFPY 80
Query: 159 ILYYYQSGGRIRRPVNVPIDIFSEEIRFYQLGE--------------------------- 191
+L++Y +G ++ + + FS+EI ++ + E
Sbjct: 81 VLHFYHTG-KLHVMAELCVFSFSQEIEYWGINEFFIDSCCSYSYHGRKVEPEQEKWDEQS 139
Query: 192 ---EAMEKFREDEGFLREEER--PLPRRDFQRQVWLLFEYPESSGPARGIAIVSVLVILI 246
F E F + + P +F+RQ+WL + P S +R +I+S+LV++
Sbjct: 140 DQESTTSSFDEILAFYNDASKFDGQPLGNFRRQLWLALDNPGYSVLSRVFSILSILVVMG 199
Query: 247 SIVIFCLETLPEFRDEKDYPASTSQDSFEAAGNSTSGSRAGASSFSDPFFVVETLCIIWF 306
SI+ CL +LP+F+ ++ GN R F +VE I WF
Sbjct: 200 SIITMCLNSLPDFQIP------------DSQGNPGEDPR---------FEIVEHFGIAWF 238
Query: 307 SFELLVRFFACPSKATFSRNIMNLIDIVAIIPYFITLGTELAERQGNGQQAMSLAILRVI 366
+FEL+ RF P F +N +NLID+++I+P++ITL L + A + +V+
Sbjct: 239 TFELVARFAVAPDFLKFFKNALNLIDLMSIVPFYITLVVNLVV-ESTPTLANLGRVAQVL 297
Query: 367 RLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADDPTS 426
RL+R+FRI KL+RHS GL+ LG TLK S +E+GLL+ +L +G+ +FS Y E ++
Sbjct: 298 RLMRIFRILKLARHSTGLRSLGATLKYSYKEVGLLLLYLSVGISIFSVVAYTIEKEE-NE 356
Query: 427 GFSSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYF 486
G ++IP +WWA V+MTTVGYGD+ P T GK+ S C +AG+L + LP+ +I + F++F
Sbjct: 357 GLATIPACWWWATVSMTTVGYGDVVPGTTAGKLTASACILAGILVVVLPITLIFNKFSHF 416
Query: 487 YHRETEGE 494
Y R+ + E
Sbjct: 417 YRRQKQLE 424
>gi|19071574 potassium voltage-gated channel, subfamily G, member 3
isoform 1 [Homo sapiens]
Length = 436
Score = 214 bits (546), Expect = 1e-55
Identities = 137/419 (32%), Positives = 224/419 (53%), Gaps = 48/419 (11%)
Query: 106 VVINISGLRFETQLKTLCQFP----ETLLGDPKRR-----MRYFDPLRNEYFFDRNRPSF 156
VV+N+ G R+ + L FP L G R +D RNEYFFDR+ +F
Sbjct: 11 VVLNVGGARYSLSRELLKDFPLRRVSRLHGCRSERDVLEVCDDYDRERNEYFFDRHSEAF 70
Query: 157 DAILYYYQSGGRIR-RPVNVPIDIFSEEIRF------------YQLGEEAMEKFR----E 199
IL Y + G++R P + ++E I + +L + + + +
Sbjct: 71 GFILLYVRGHGKLRFAPRMCELSFYNEMIYWGLEGAHLEYCCQRRLDDRMSDTYTFYSAD 130
Query: 200 DEGFL-REEERP-----LPRRDFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCL 253
+ G L R+E RP P R + ++ FE P SS A+ +A VSV+ +++S+V+ C
Sbjct: 131 EPGVLGRDEARPGGAEAAPSRRWLERMRRTFEEPTSSLAAQILASVSVVFVIVSMVVLCA 190
Query: 254 ETLPEFRDEKDYPASTSQDSFEAAGNSTSGSRAGASSFSDPFFVVETLCIIWFSFELLVR 313
TLP++R+ A+ S + SR A +P ++E +CI WF+ E +VR
Sbjct: 191 STLPDWRN-----AAADNRSLD------DRSRYSAGPGREPSGIIEAICIGWFTAECIVR 239
Query: 314 FFACPSKATFSRNIMNLIDIVAIIPYFITLGTELAERQGNGQQAMSLAILRVIRLVRVFR 373
F +K F + +N+ID++AI PY+I++ + + N Q + LRV+R++R+F
Sbjct: 240 FIVSKNKCEFVKRPLNIIDLLAITPYYISVLMTVFTGE-NSQLQRAGVTLRVLRMMRIFW 298
Query: 374 IFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAE----ADDPTSGFS 429
+ KL+RH GLQ LG TLK RE+ +L+ F+ + + +FS+ E + F+
Sbjct: 299 VIKLARHFIGLQTLGLTLKRCYREMVMLLVFICVAMAIFSALSQLLEHGLDLETSNKDFT 358
Query: 430 SIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYH 488
SIP A WW +++MTTVGYGDM+P+T+ G+I+G +C ++G++ +ALP+ I +F YH
Sbjct: 359 SIPAACWWVIISMTTVGYGDMYPITVPGRILGGVCVVSGIVLLALPITFIYHSFVQCYH 417
>gi|27436993 potassium voltage-gated channel, subfamily G, member 3
isoform 2 [Homo sapiens]
Length = 425
Score = 209 bits (533), Expect = 4e-54
Identities = 135/419 (32%), Positives = 221/419 (52%), Gaps = 59/419 (14%)
Query: 106 VVINISGLRFETQLKTLCQFP----ETLLGDPKRR-----MRYFDPLRNEYFFDRNRPSF 156
VV+N+ G R+ + L FP L G R +D RNEYFFDR+ +F
Sbjct: 11 VVLNVGGARYSLSRELLKDFPLRRVSRLHGCRSERDVLEVCDDYDRERNEYFFDRHSEAF 70
Query: 157 DAILYYYQSGGRIR-RPVNVPIDIFSEEIRF------------YQLGEEAMEKFR----E 199
IL Y + G++R P + ++E I + +L + + + +
Sbjct: 71 GFILLYVRGHGKLRFAPRMCELSFYNEMIYWGLEGAHLEYCCQRRLDDRMSDTYTFYSAD 130
Query: 200 DEGFL-REEERP-----LPRRDFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCL 253
+ G L R+E RP P R + ++ FE P SS A+ +A VSV+ +++S+V+ C
Sbjct: 131 EPGVLGRDEARPGGAEAAPSRRWLERMRRTFEEPTSSLAAQILASVSVVFVIVSMVVLCA 190
Query: 254 ETLPEFRDEKDYPASTSQDSFEAAGNSTSGSRAGASSFSDPFFVVETLCIIWFSFELLVR 313
TLP++R N+ + +R S D ++E +CI WF+ E +VR
Sbjct: 191 STLPDWR------------------NAAADNR----SLDDRSRIIEAICIGWFTAECIVR 228
Query: 314 FFACPSKATFSRNIMNLIDIVAIIPYFITLGTELAERQGNGQQAMSLAILRVIRLVRVFR 373
F +K F + +N+ID++AI PY+I++ + + N Q + LRV+R++R+F
Sbjct: 229 FIVSKNKCEFVKRPLNIIDLLAITPYYISVLMTVFTGE-NSQLQRAGVTLRVLRMMRIFW 287
Query: 374 IFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAE----ADDPTSGFS 429
+ KL+RH GLQ LG TLK RE+ +L+ F+ + + +FS+ E + F+
Sbjct: 288 VIKLARHFIGLQTLGLTLKRCYREMVMLLVFICVAMAIFSALSQLLEHGLDLETSNKDFT 347
Query: 430 SIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYH 488
SIP A WW +++MTTVGYGDM+P+T+ G+I+G +C ++G++ +ALP+ I +F YH
Sbjct: 348 SIPAACWWVIISMTTVGYGDMYPITVPGRILGGVCVVSGIVLLALPITFIYHSFVQCYH 406
>gi|27436988 potassium voltage-gated channel, subfamily G, member 1
[Homo sapiens]
Length = 513
Score = 209 bits (532), Expect = 6e-54
Identities = 142/439 (32%), Positives = 218/439 (49%), Gaps = 67/439 (15%)
Query: 105 RVVINISGLRFETQLKTLCQFPETLLGDPKRRMRYFDPLR---------NEYFFDRNRPS 155
R++IN+ G+++ TL +FP T LG K + D L NE+FFDRN +
Sbjct: 64 RIIINVGGIKYSLPWTTLDEFPLTRLGQLKACTNFDDILNVCDDYDVTCNEFFFDRNPGA 123
Query: 156 FDAILYYYQSGGRIRRPVNVPIDIFSEEIRFYQLGE-------------------EAMEK 196
F IL + ++G ++R + F EE+ ++ + E E +E+
Sbjct: 124 FGTILTFLRAG-KLRLLREMCALSFQEELLYWGIAEDHLDGCCKRRYLQKIEEFAEMVER 182
Query: 197 FREDEGFL---REEERPLPRRD----FQRQVWLLFEYPESSGPARGIAIVSVLVILISIV 249
ED+ R+ E P R++ + E P S P + A +SVL + ++ V
Sbjct: 183 EEEDDALDSEGRDSEGPAEGEGRLGRCMRRLRDMVERPHSGLPGKVFACLSVLFVTVTAV 242
Query: 250 IFCLETLPEFRDEKDYPASTSQDSFEAAGNSTSGSRAGASSFSDPFFVVETLCIIWFSFE 309
+ TLP R+E++ + S F+VE++C+ WFS E
Sbjct: 243 NLSVSTLPSLREEEE--------------------QGHCSQMCHNVFIVESVCVGWFSLE 282
Query: 310 LLVRFFACPSKATFSRNIMNLIDIVAIIPYFITL---GTELAERQ---GNGQQAMSLAIL 363
L+R PSK F R+ + LID+VAI+PY+ITL G R+ GN +L
Sbjct: 283 FLLRLIQAPSKFAFLRSPLTLIDLVAILPYYITLLVDGAAAGRRKPGAGNSYLDKVGLVL 342
Query: 364 RVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAE--- 420
RV+R +R+ + +L+RHS GLQ LG T + RE GLL+ FL + + LF+ +Y E
Sbjct: 343 RVLRALRILYVMRLARHSLGLQTLGLTARRCTREFGLLLLFLCVAIALFAPLLYVIENEM 402
Query: 421 ADDPTSGFSSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIV 480
AD P F+SIP +WWAV+TMTTVGYGDM P + G++V ++G+L +A PV I
Sbjct: 403 ADSPE--FTSIPACYWWAVITMTTVGYGDMVPRSTPGQVVALSSILSGILLMAFPVTSIF 460
Query: 481 SNFNYFYHRETEGEEQSQY 499
F+ Y + +E+ +
Sbjct: 461 HTFSRSYLELKQEQERVMF 479
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.138 0.420
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,304,290
Number of Sequences: 37866
Number of extensions: 1258238
Number of successful extensions: 6225
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 159
Number of HSP's successfully gapped in prelim test: 117
Number of HSP's that attempted gapping in prelim test: 5468
Number of HSP's gapped (non-prelim): 635
length of query: 575
length of database: 18,247,518
effective HSP length: 108
effective length of query: 467
effective length of database: 14,157,990
effective search space: 6611781330
effective search space used: 6611781330
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.