Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 87042275
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|87042275 erythrocyte protein band 4.1-like 4 [Homo sapiens]
(686 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|87042275 erythrocyte protein band 4.1-like 4 [Homo sapiens] 1400 0.0
gi|40254949 erythrocyte membrane protein band 4.1 like 5 [Homo s... 288 2e-77
gi|110624794 erythrocyte membrane protein band 4.1 like 4B isofo... 279 5e-75
gi|110624790 erythrocyte membrane protein band 4.1 like 4B isofo... 279 5e-75
gi|4506295 protein tyrosine phosphatase, non-receptor type 4 [Ho... 277 3e-74
gi|30061491 erythrocyte membrane protein band 4.1-like 1 isoform... 265 1e-70
gi|32490572 erythrocyte membrane protein band 4.1-like 3 [Homo s... 263 4e-70
gi|30061489 erythrocyte membrane protein band 4.1-like 1 isoform... 262 7e-70
gi|42716291 erythrocyte membrane protein band 4.1 (elliptocytosi... 253 3e-67
gi|4758274 erythrocyte membrane protein band 4.1 (elliptocytosis... 253 3e-67
gi|94721308 FERM domain containing 5 isoform 2 [Homo sapiens] 253 3e-67
gi|117500790 FERM domain containing 3 [Homo sapiens] 251 1e-66
gi|207113199 erythrocyte membrane protein band 4.1-like 2 isofor... 246 4e-65
gi|207113195 erythrocyte membrane protein band 4.1-like 2 isofor... 246 4e-65
gi|4503579 erythrocyte membrane protein band 4.1-like 2 isoform ... 246 4e-65
gi|42716289 erythrocyte membrane protein band 4.1 (elliptocytosi... 221 2e-57
gi|223941876 protein tyrosine phosphatase, non-receptor type 3 i... 196 5e-50
gi|223941879 protein tyrosine phosphatase, non-receptor type 3 i... 194 2e-49
gi|5031633 FERM, RhoGEF, and pleckstrin domain protein 1 isoform... 189 7e-48
gi|7662310 FERM, RhoGEF and pleckstrin domain protein 2 [Homo sa... 174 2e-43
gi|34916000 FERM domain containing 7 [Homo sapiens] 172 9e-43
gi|150418005 protein tyrosine phosphatase, non-receptor type 21 ... 138 2e-32
gi|223941882 protein tyrosine phosphatase, non-receptor type 3 i... 136 7e-32
gi|161702986 ezrin [Homo sapiens] 134 2e-31
gi|21614499 ezrin [Homo sapiens] 134 2e-31
gi|223941885 protein tyrosine phosphatase, non-receptor type 3 i... 134 3e-31
gi|4506467 radixin [Homo sapiens] 132 1e-30
gi|4505257 moesin [Homo sapiens] 129 9e-30
gi|34328899 protein tyrosine phosphatase, non-receptor type 14 [... 128 2e-29
gi|32967254 neurofibromin 2 isoform 2 [Homo sapiens] 122 8e-28
>gi|87042275 erythrocyte protein band 4.1-like 4 [Homo sapiens]
Length = 686
Score = 1400 bits (3625), Expect = 0.0
Identities = 686/686 (100%), Positives = 686/686 (100%)
Query: 1 MGCFCAVPEEFYCEVLLLDESKLTLTTQQQGIKKSTKGSVVLDHVFHHVNLVEIDYFGLR 60
MGCFCAVPEEFYCEVLLLDESKLTLTTQQQGIKKSTKGSVVLDHVFHHVNLVEIDYFGLR
Sbjct: 1 MGCFCAVPEEFYCEVLLLDESKLTLTTQQQGIKKSTKGSVVLDHVFHHVNLVEIDYFGLR 60
Query: 61 YCDRSHQTYWLDPAKTLAEHKELINTGPPYTLYFGIKFYAEDPCKLKEEITRYQFFLQVK 120
YCDRSHQTYWLDPAKTLAEHKELINTGPPYTLYFGIKFYAEDPCKLKEEITRYQFFLQVK
Sbjct: 61 YCDRSHQTYWLDPAKTLAEHKELINTGPPYTLYFGIKFYAEDPCKLKEEITRYQFFLQVK 120
Query: 121 QDVLQGRLPCPVNTAAQLGAYAIQSELGDYDPYKHTAGYVSEYRFVPDQKEELEEAIERI 180
QDVLQGRLPCPVNTAAQLGAYAIQSELGDYDPYKHTAGYVSEYRFVPDQKEELEEAIERI
Sbjct: 121 QDVLQGRLPCPVNTAAQLGAYAIQSELGDYDPYKHTAGYVSEYRFVPDQKEELEEAIERI 180
Query: 181 HKTLMGQIPSEAELNYLRTAKSLEMYGVDLHPVYGENKSEYFLGLTPVGVVVYKNKKQVG 240
HKTLMGQIPSEAELNYLRTAKSLEMYGVDLHPVYGENKSEYFLGLTPVGVVVYKNKKQVG
Sbjct: 181 HKTLMGQIPSEAELNYLRTAKSLEMYGVDLHPVYGENKSEYFLGLTPVGVVVYKNKKQVG 240
Query: 241 KYFWPRITKVHFKETQFELRVLGKDCNETSFFFEARSKTACKHLWKCSVEHHTFFRMPEN 300
KYFWPRITKVHFKETQFELRVLGKDCNETSFFFEARSKTACKHLWKCSVEHHTFFRMPEN
Sbjct: 241 KYFWPRITKVHFKETQFELRVLGKDCNETSFFFEARSKTACKHLWKCSVEHHTFFRMPEN 300
Query: 301 ESNSLSRKLSKFGSIRYKHRYSGRTALQMSRDLSIQLPRPDQNVTRSRSKTYPKRIAQTQ 360
ESNSLSRKLSKFGSIRYKHRYSGRTALQMSRDLSIQLPRPDQNVTRSRSKTYPKRIAQTQ
Sbjct: 301 ESNSLSRKLSKFGSIRYKHRYSGRTALQMSRDLSIQLPRPDQNVTRSRSKTYPKRIAQTQ 360
Query: 361 PAESNSISRITANMENGENEGTIKIIAPSPVKSFKKAKNENSPDTQRSKSHAPWEENGPQ 420
PAESNSISRITANMENGENEGTIKIIAPSPVKSFKKAKNENSPDTQRSKSHAPWEENGPQ
Sbjct: 361 PAESNSISRITANMENGENEGTIKIIAPSPVKSFKKAKNENSPDTQRSKSHAPWEENGPQ 420
Query: 421 SGLYNSPSDRTKSPKFPYTRRRNPSCGSDNDSVQPVRRRKAHNSGEDSDLKQRRRSRSRC 480
SGLYNSPSDRTKSPKFPYTRRRNPSCGSDNDSVQPVRRRKAHNSGEDSDLKQRRRSRSRC
Sbjct: 421 SGLYNSPSDRTKSPKFPYTRRRNPSCGSDNDSVQPVRRRKAHNSGEDSDLKQRRRSRSRC 480
Query: 481 NTSSGSESENSNREYRKKRNRIRQENDMVDSAPQWEAVLRRQKEKNQADPNNRRSRHRSR 540
NTSSGSESENSNREYRKKRNRIRQENDMVDSAPQWEAVLRRQKEKNQADPNNRRSRHRSR
Sbjct: 481 NTSSGSESENSNREYRKKRNRIRQENDMVDSAPQWEAVLRRQKEKNQADPNNRRSRHRSR 540
Query: 541 SRSPDIQAKEELWKHIQKELVDPSGLSEEQLKEIPYTKIETQGDPIRIRHSHSPRSYRQY 600
SRSPDIQAKEELWKHIQKELVDPSGLSEEQLKEIPYTKIETQGDPIRIRHSHSPRSYRQY
Sbjct: 541 SRSPDIQAKEELWKHIQKELVDPSGLSEEQLKEIPYTKIETQGDPIRIRHSHSPRSYRQY 600
Query: 601 RRSQCSDGERSVLSEVNSKTDLVPPLPVTHSSDAQGSGDATVHQRRNGSKDSLMEEKPQT 660
RRSQCSDGERSVLSEVNSKTDLVPPLPVTHSSDAQGSGDATVHQRRNGSKDSLMEEKPQT
Sbjct: 601 RRSQCSDGERSVLSEVNSKTDLVPPLPVTHSSDAQGSGDATVHQRRNGSKDSLMEEKPQT 660
Query: 661 STNNLAGKHTAKTIKTIQASRLKTET 686
STNNLAGKHTAKTIKTIQASRLKTET
Sbjct: 661 STNNLAGKHTAKTIKTIQASRLKTET 686
>gi|40254949 erythrocyte membrane protein band 4.1 like 5 [Homo
sapiens]
Length = 733
Score = 288 bits (736), Expect = 2e-77
Identities = 164/413 (39%), Positives = 238/413 (57%), Gaps = 29/413 (7%)
Query: 13 CEVLLLDESKLTLTTQQQGIKKSTKGSVVLDHVFHHVNLVEIDYFGLRYCDRSHQTYWLD 72
C V LLD + +++ + K KG + D + +H++L+E DYFGLR+ D + +WLD
Sbjct: 45 CRVSLLDGTDVSVD-----LPKKAKGQELFDQIMYHLDLIESDYFGLRFMDSAQVAHWLD 99
Query: 73 PAKTLAEHKELINTGPPYTLYFGIKFYAEDPCKLKEEITRYQFFLQVKQDVLQGRLPCPV 132
K++ K+ + G PY L+ +KFY+ +P L+EE+TRY F LQ+KQD+L G+L CP
Sbjct: 100 GTKSI---KKQVKIGSPYCLHLRVKFYSSEPNNLREELTRYLFVLQLKQDILSGKLDCPF 156
Query: 133 NTAAQLGAYAIQSELGDYDPYKHTAGYVSEYRFVPDQKEELEEAIERIHKTLMGQIPSEA 192
+TA QL AY +Q+ELGDYD +H+ VSE+RFVP Q EE+E AI K GQ P++A
Sbjct: 157 DTAVQLAAYNLQAELGDYDLAEHSPELVSEFRFVPIQTEEMELAIFEKWKEYRGQTPAQA 216
Query: 193 ELNYLRTAKSLEMYGVDLHPVYGENKSEYFLGLTPVGVVVYKNKKQVGKYFWPRITKVHF 252
E NYL AK LEMYGVD+H V + ++Y LGLTP GV+V++ ++G +FWP+IT++ F
Sbjct: 217 ETNYLNKAKWLEMYGVDMHVVKARDGNDYSLGLTPTGVLVFEGDTKIGLFFWPKITRLDF 276
Query: 253 KETQFELRVL-----GKDCNETSFFFEARSKTACKHLWKCSVEHHTFFRMPENESNSLSR 307
K+ + L V+ GK+ E +F F ACKHLWKC+VEHH FFR+ S R
Sbjct: 277 KKNKLTLVVVEDDDQGKE-QEHTFVFRLDHPKACKHLWKCAVEHHAFFRLRGPVQKSSHR 335
Query: 308 KLSKFGSIRYKHRYSGRTALQMSRDLSIQLPRPDQNVTRSRSKTYPKRIAQ-----TQPA 362
S F + + RYSG+T Q ++ R + R SK Y +R Q T+P
Sbjct: 336 --SGFIRLGSRFRYSGKTEYQTTK---TNKARRSTSFERRPSKRYSRRTLQMKACATKP- 389
Query: 363 ESNSISRITANMENGENEG----TIKIIAPSPVKSFKKAKNENSPDTQRSKSH 411
E S+ + NG + + ++PS + + EN P + + H
Sbjct: 390 EELSVHNNVSTQSNGSQQAWGMRSALPVSPSISSAPVPVEIENLPQSPGTDQH 442
>gi|110624794 erythrocyte membrane protein band 4.1 like 4B isoform
1 [Homo sapiens]
Length = 518
Score = 279 bits (714), Expect = 5e-75
Identities = 151/377 (40%), Positives = 222/377 (58%), Gaps = 17/377 (4%)
Query: 6 AVPEEFYCEVLLLDESKLTLTTQQQGIKKSTKGSVVLDHVFHHVNLVEIDYFGLRYCDRS 65
A YC V LLD +++++ + K KG + D + +H++LVE DYFGL++ D +
Sbjct: 80 AAKATLYCRVFLLDGTEVSVD-----LPKHAKGQDLFDQIVYHLDLVETDYFGLQFLDSA 134
Query: 66 HQTYWLDPAKTLAEHKELINTGPPYTLYFGIKFYAEDPCKLKEEITRYQFFLQVKQDVLQ 125
+WLD AK + K+ + GP Y L+F +K+Y+ +P L+EE TRY F LQ++ D+L
Sbjct: 135 QVAHWLDHAKPI---KKQMKIGPAYALHFRVKYYSSEPNNLREEFTRYLFVLQLRHDILS 191
Query: 126 GRLPCPVNTAAQLGAYAIQSELGDYDPYKHTAGYVSEYRFVPDQKEELEEAIERIHKTLM 185
G+L CP TA +L A +Q+ELG+ + +HT VSE+RF+P+Q E +E I + K
Sbjct: 192 GKLKCPYETAVELAALCLQAELGECELPEHTPELVSEFRFIPNQTEAMEFDIFQRWKECR 251
Query: 186 GQIPSEAELNYLRTAKSLEMYGVDLHPVYGENKSEYFLGLTPVGVVVYKNKKQVGKYFWP 245
G+ P++AEL+YL AK LEMYGVD+H V G + EY LGLTP G+++++ ++G +FWP
Sbjct: 252 GKSPAQAELSYLNKAKWLEMYGVDMHVVRGRDGCEYSLGLTPTGILIFEGANKIGLFFWP 311
Query: 246 RITKVHFKETQFELRVLGKDC----NETSFFFEARSKTACKHLWKCSVEHHTFFRMPENE 301
+ITK+ FK+++ L V+ D E +F F S CKHLWKC+VEHH FFR+
Sbjct: 312 KITKMDFKKSKLTLVVVEDDDQGREQEHTFVFRLDSARTCKHLWKCAVEHHAFFRL-RTP 370
Query: 302 SNSLSRKLSKFGSIRYKHRYSGRTALQMSRDLSIQLPRPDQNVTRSRSKTYPKRIAQTQP 361
NS S + S F + + R+SGRT Q + + R R SK YP R T
Sbjct: 371 GNSKSNR-SDFIRLGSRFRFSGRTEYQATHGSRL---RRTSTFERKPSKRYPSRRHSTFK 426
Query: 362 AESNSISRITANMENGE 378
A + I+ + N E
Sbjct: 427 ASNPVIAAQLCSKTNPE 443
>gi|110624790 erythrocyte membrane protein band 4.1 like 4B isoform
2 [Homo sapiens]
Length = 900
Score = 279 bits (714), Expect = 5e-75
Identities = 151/377 (40%), Positives = 222/377 (58%), Gaps = 17/377 (4%)
Query: 6 AVPEEFYCEVLLLDESKLTLTTQQQGIKKSTKGSVVLDHVFHHVNLVEIDYFGLRYCDRS 65
A YC V LLD +++++ + K KG + D + +H++LVE DYFGL++ D +
Sbjct: 80 AAKATLYCRVFLLDGTEVSVD-----LPKHAKGQDLFDQIVYHLDLVETDYFGLQFLDSA 134
Query: 66 HQTYWLDPAKTLAEHKELINTGPPYTLYFGIKFYAEDPCKLKEEITRYQFFLQVKQDVLQ 125
+WLD AK + K+ + GP Y L+F +K+Y+ +P L+EE TRY F LQ++ D+L
Sbjct: 135 QVAHWLDHAKPI---KKQMKIGPAYALHFRVKYYSSEPNNLREEFTRYLFVLQLRHDILS 191
Query: 126 GRLPCPVNTAAQLGAYAIQSELGDYDPYKHTAGYVSEYRFVPDQKEELEEAIERIHKTLM 185
G+L CP TA +L A +Q+ELG+ + +HT VSE+RF+P+Q E +E I + K
Sbjct: 192 GKLKCPYETAVELAALCLQAELGECELPEHTPELVSEFRFIPNQTEAMEFDIFQRWKECR 251
Query: 186 GQIPSEAELNYLRTAKSLEMYGVDLHPVYGENKSEYFLGLTPVGVVVYKNKKQVGKYFWP 245
G+ P++AEL+YL AK LEMYGVD+H V G + EY LGLTP G+++++ ++G +FWP
Sbjct: 252 GKSPAQAELSYLNKAKWLEMYGVDMHVVRGRDGCEYSLGLTPTGILIFEGANKIGLFFWP 311
Query: 246 RITKVHFKETQFELRVLGKDC----NETSFFFEARSKTACKHLWKCSVEHHTFFRMPENE 301
+ITK+ FK+++ L V+ D E +F F S CKHLWKC+VEHH FFR+
Sbjct: 312 KITKMDFKKSKLTLVVVEDDDQGREQEHTFVFRLDSARTCKHLWKCAVEHHAFFRL-RTP 370
Query: 302 SNSLSRKLSKFGSIRYKHRYSGRTALQMSRDLSIQLPRPDQNVTRSRSKTYPKRIAQTQP 361
NS S + S F + + R+SGRT Q + + R R SK YP R T
Sbjct: 371 GNSKSNR-SDFIRLGSRFRFSGRTEYQATHGSRL---RRTSTFERKPSKRYPSRRHSTFK 426
Query: 362 AESNSISRITANMENGE 378
A + I+ + N E
Sbjct: 427 ASNPVIAAQLCSKTNPE 443
>gi|4506295 protein tyrosine phosphatase, non-receptor type 4 [Homo
sapiens]
Length = 926
Score = 277 bits (708), Expect = 3e-74
Identities = 149/362 (41%), Positives = 220/362 (60%), Gaps = 13/362 (3%)
Query: 10 EFYCEVLLLDESKLTLTTQQQGIKKSTKGSVVLDHVFHHVNLVEIDYFGLRYCDRSHQT- 68
E C +LLLD T Q + K +G V+LD VF H++L E DYFGL+ D S
Sbjct: 28 EVVCNILLLDN-----TVQAFKVNKHDQGQVLLDVVFKHLDLTEQDYFGLQLADDSTDNP 82
Query: 69 YWLDPAKTLAEHKELINTGPPYTLYFGIKFYAEDPCKLKEEITRYQFFLQVKQDVLQGRL 128
WLDP K + ++ + G PY+L F +KF+ DP KL+EE TRYQ+FLQ+KQD+L GRL
Sbjct: 83 RWLDPNKPI---RKQLKRGSPYSLNFRVKFFVSDPNKLQEEYTRYQYFLQIKQDILTGRL 139
Query: 129 PCPVNTAAQLGAYAIQSELGDYDPYKHTAGYVSEYRFVPDQKEELEEAIERIHKTLMGQI 188
PCP NTAA L ++A+QSELGDYD ++ +GY+S+Y F+P+Q ++ E+ I ++H+ +G
Sbjct: 140 PCPSNTAALLASFAVQSELGDYDQSENLSGYLSDYSFIPNQPQDFEKEIAKLHQQHIGLS 199
Query: 189 PSEAELNYLRTAKSLEMYGVDLHPVYGENKSEYFLGLTPVGVVVYKNKKQVGKYFWPRIT 248
P+EAE NYL TA++LE+YGV+ H ++ +E +G+ G+++YKN+ ++ + W +I
Sbjct: 200 PAEAEFNYLNTARTLELYGVEFHYARDQSNNEIMIGVMSGGILIYKNRVRMNTFPWLKIV 259
Query: 249 KVHFKETQF--ELRVLGKDCNETSFFFEARSKTACKHLWKCSVEHHTFFRMPENESNSLS 306
K+ FK QF +LR + ET F + ACK+LWK VEHHTFFR+ +
Sbjct: 260 KISFKCKQFFIQLRKELHESRETLLGFNMVNYRACKNLWKACVEHHTFFRL-DRPLPPQK 318
Query: 307 RKLSKFGSIRYKHRYSGRTALQMSRDLSIQLPRPDQNVTRSRSKTYPKRIAQTQPAESNS 366
+ + ++ K RY GRT +Q S + D+ RS SK +++ + NS
Sbjct: 319 NFFAHYFTLGSKFRYCGRTEVQ-SVQYGKEKANKDRVFARSPSKPLARKLMDWEVVSRNS 377
Query: 367 IS 368
IS
Sbjct: 378 IS 379
>gi|30061491 erythrocyte membrane protein band 4.1-like 1 isoform b
[Homo sapiens]
Length = 779
Score = 265 bits (676), Expect = 1e-70
Identities = 169/504 (33%), Positives = 249/504 (49%), Gaps = 46/504 (9%)
Query: 13 CEVLLLDESKLTLTTQQQGIKKSTKGSVVLDHVFHHVNLVEIDYFGLRYCDRSHQTYWLD 72
C V LLD S+ ++ G +G V+ D V H+NL+E DYFGL +CD Q WLD
Sbjct: 37 CRVTLLDASEYECEVEKHG-----RGQVLFDLVCEHLNLLEKDYFGLTFCDADSQKNWLD 91
Query: 73 PAKTLAEHKELINTGPPYTLYFGIKFYAEDPCKLKEEITRYQFFLQVKQDVLQGRLPCPV 132
P+K E K+ I + P + F +KFY DP +L E+ITRY LQ++ D++ GRLPC
Sbjct: 92 PSK---EIKKQIRSSP-WNFAFTVKFYPPDPAQLTEDITRYYLCLQLRADIITGRLPCSF 147
Query: 133 NTAAQLGAYAIQSELGDYDPYKHTAGYVSEYRFVPDQKEELEEAIERIHKTLMGQIPSEA 192
T A LG+YA+Q+ELGDYD +H YVSE RF P+Q ELEE I +HKT G P EA
Sbjct: 148 VTHALLGSYAVQAELGDYDAEEHVGNYVSELRFAPNQTRELEERIMELHKTYRGMTPGEA 207
Query: 193 ELNYLRTAKSLEMYGVDLHPVYGENKSEYFLGLTPVGVVVYKNKKQVGKYFWPRITKVHF 252
E+++L AK L MYGVDLH + LG+ G+++Y+++ ++ ++ WP+I K+ +
Sbjct: 208 EIHFLENAKKLSMYGVDLHHAKDSEGIDIMLGVCANGLLIYRDRLRINRFAWPKILKISY 267
Query: 253 KETQFELRVLGKDCN--ETSFFFEARSKTACKHLWKCSVEHHTFFRM--PENESNSLSRK 308
K + F +++ + E++ F+ + + K LWK +EHHTFFR+ PE
Sbjct: 268 KRSNFYIKIRPGEYEQFESTIGFKLPNHRSAKRLWKVCIEHHTFFRLVSPEPPPKGFLVM 327
Query: 309 LSKFGSIRYKHRYSGRTALQMSRDLSIQLPRPDQNVTRSRSKTY-------------PKR 355
SKF RYSGRT Q +R S + RP RS SK Y P
Sbjct: 328 GSKF-------RYSGRTQAQ-TRQASALIDRPAPFFERSSSKRYTMSRSLDGAEFSRPAS 379
Query: 356 IAQTQPAESNSISRITANMENGENEGTIKIIAPSPVKSFKKAKNENSPDTQRSKSHAPWE 415
+++ A + R G+ + +P K K+ K + P+ K A
Sbjct: 380 VSENHDAGPDGDKRDEDGESGGQRSEAEEGEVRTPTK-IKELKFLDKPEDVLLKHQASIN 438
Query: 416 E-----NGPQSGLYNSPSDRTKSPKFPYTRRRNPSCGSDNDSVQPVRRRKAHNSGEDSDL 470
E P S L + D + + P +P+ S + + R G + +
Sbjct: 439 ELKRTLKEPNSKLIHRDRDWERERRLP----SSPASPSPKGTPEKANERAGLREGSEEKV 494
Query: 471 KQRRRSRSRCNTSSGSESENSNRE 494
K R +T G E ++ R+
Sbjct: 495 KPPRPRAPESDT--GDEDQDQERD 516
>gi|32490572 erythrocyte membrane protein band 4.1-like 3 [Homo
sapiens]
Length = 1087
Score = 263 bits (672), Expect = 4e-70
Identities = 140/347 (40%), Positives = 208/347 (59%), Gaps = 17/347 (4%)
Query: 8 PEEFYCEVLLLDESKLTLTTQQQGIKKSTKGSVVLDHVFHHVNLVEIDYFGLRYCDRSHQ 67
P+ C+V+LLD S+ T ++K ++G V+ D V H+NL+E DYFGL Y D +Q
Sbjct: 107 PKSMQCKVILLDGSEYTCD-----VEKRSRGQVLFDKVCEHLNLLEKDYFGLTYRDAENQ 161
Query: 68 TYWLDPAKTLAEHKELINTGPPYTLYFGIKFYAEDPCKLKEEITRYQFFLQVKQDVLQGR 127
WLDPAK E K+ + +G + F +KFY DP +L E+ITRY LQ++ D++ GR
Sbjct: 162 KNWLDPAK---EIKKQVRSGA-WHFSFNVKFYPPDPAQLSEDITRYYLCLQLRDDIVSGR 217
Query: 128 LPCPVNTAAQLGAYAIQSELGDYDPYKHTAGYVSEYRFVPDQKEELEEAIERIHKTLMGQ 187
LPC T A LG+Y +QSELGDYDP + + Y+SE+RF P+ +ELE+ + +HK+ G
Sbjct: 218 LPCSFVTLALLGSYTVQSELGDYDPDECGSDYISEFRFAPNHTKELEDKVIELHKSHRGM 277
Query: 188 IPSEAELNYLRTAKSLEMYGVDLHPVYGENKSEYFLGLTPVGVVVYKNKKQVGKYFWPRI 247
P+EAE+++L AK L MYGVDLH E LG+ G+++Y+++ ++ ++ WP++
Sbjct: 278 TPAEAEMHFLENAKKLSMYGVDLHHAKDSEGVEIMLGVCASGLLIYRDRLRINRFAWPKV 337
Query: 248 TKVHFKETQFELRVLGKDCN--ETSFFFEARSKTACKHLWKCSVEHHTFFRMPENESNSL 305
K+ +K F +++ + E++ F+ + A K LWK VEHHTFFR+ E+
Sbjct: 338 LKISYKRNNFYIKIRPGEFEQFESTIGFKLPNHRAAKRLWKVCVEHHTFFRLLLPEAPP- 396
Query: 306 SRKLSKFGSIRYKHRYSGRTALQMSRDLSIQLPRPDQNVTRSRSKTY 352
KF ++ K RYSGRT Q +R S + RP RS SK Y
Sbjct: 397 ----KKFLTLGSKFRYSGRTQAQ-TRRASALIDRPAPYFERSSSKRY 438
>gi|30061489 erythrocyte membrane protein band 4.1-like 1 isoform a
[Homo sapiens]
Length = 881
Score = 262 bits (670), Expect = 7e-70
Identities = 171/517 (33%), Positives = 253/517 (48%), Gaps = 60/517 (11%)
Query: 13 CEVLLLDESKLTLTTQQQGIKKSTKGSVVLDHVFHHVNLVEIDYFGLRYCDRSHQTYWLD 72
C V LLD S+ ++ G +G V+ D V H+NL+E DYFGL +CD Q WLD
Sbjct: 99 CRVTLLDASEYECEVEKHG-----RGQVLFDLVCEHLNLLEKDYFGLTFCDADSQKNWLD 153
Query: 73 PAKTLAEHKELINTGPPYTLYFGIKFYAEDPCKLKEEITRYQFFLQVKQDVLQGRLPCPV 132
P+K E K+ I + P + F +KFY DP +L E+ITRY LQ++ D++ GRLPC
Sbjct: 154 PSK---EIKKQIRSSP-WNFAFTVKFYPPDPAQLTEDITRYYLCLQLRADIITGRLPCSF 209
Query: 133 NTAAQLGAYAIQSELGDYDPYKHTAGYVSEYRFVPDQKEELEEAIERIHKTLMGQIPSEA 192
T A LG+YA+Q+ELGDYD +H YVSE RF P+Q ELEE I +HKT G P EA
Sbjct: 210 VTHALLGSYAVQAELGDYDAEEHVGNYVSELRFAPNQTRELEERIMELHKTYRGMTPGEA 269
Query: 193 ELNYLRTAKSLEMYGVDLHPVYGENKSEYFLGLTPVGVVVYKNKKQVGKYFWPRITKVHF 252
E+++L AK L MYGVDLH + LG+ G+++Y+++ ++ ++ WP+I K+ +
Sbjct: 270 EIHFLENAKKLSMYGVDLHHAKDSEGIDIMLGVCANGLLIYRDRLRINRFAWPKILKISY 329
Query: 253 KETQFELRVLGKDCN--ETSFFFEARSKTACKHLWKCSVEHHTFFRM--PENESNSLSRK 308
K + F +++ + E++ F+ + + K LWK +EHHTFFR+ PE
Sbjct: 330 KRSNFYIKIRPGEYEQFESTIGFKLPNHRSAKRLWKVCIEHHTFFRLVSPEPPPKGFLVM 389
Query: 309 LSKFGSIRYKHRYSGRTALQMSRDLSIQLPRPDQNVTRSRSKTY-------------PKR 355
SKF RYSGRT Q +R S + RP RS SK Y P
Sbjct: 390 GSKF-------RYSGRTQAQ-TRQASALIDRPAPFFERSSSKRYTMSRSLDGAEFSRPAS 441
Query: 356 IAQTQPAESNSISRITANMENGE----NEGTIKIIAPSPVKSFK---------KAKNENS 402
+++ A + R G+ EG ++ P+ +K K K + +
Sbjct: 442 VSENHDAGPDGDKRDEDGESGGQRSEAEEGEVR--TPTKIKELKPEQETTPRHKQEFLDK 499
Query: 403 PDTQRSKSHAPWEE-----NGPQSGLYNSPSDRTKSPKFPYTRRRNPSCGSDNDSVQPVR 457
P+ K A E P S L + D + + P +P+ S + +
Sbjct: 500 PEDVLLKHQASINELKRTLKEPNSKLIHRDRDWERERRLP----SSPASPSPKGTPEKAN 555
Query: 458 RRKAHNSGEDSDLKQRRRSRSRCNTSSGSESENSNRE 494
R G + +K R +T G E ++ R+
Sbjct: 556 ERAGLREGSEEKVKPPRPRAPESDT--GDEDQDQERD 590
>gi|42716291 erythrocyte membrane protein band 4.1 (elliptocytosis
1, RH-linked) isoform 2 [Homo sapiens]
Length = 641
Score = 253 bits (647), Expect = 3e-67
Identities = 152/409 (37%), Positives = 222/409 (54%), Gaps = 28/409 (6%)
Query: 12 YCEVLLLDESKLTLTTQQQGIKKSTKGSVVLDHVFHHVNLVEIDYFGLRYCDRSHQTYWL 71
+C+V LLD+ T + ++K KG +L V H+NL+E DYFGL D + WL
Sbjct: 2 HCKVSLLDD-----TVYECVVEKHAKGQDLLKRVCEHLNLLEEDYFGLAIWDNATSKTWL 56
Query: 72 DPAKTLAEHKELINTGPPYTLYFGIKFYAEDPCKLKEEITRYQFFLQVKQDVLQGRLPCP 131
D AK + + G P+ F +KFY DP +L E+ITRY LQ++QD++ GRLPC
Sbjct: 57 DSAKEIKKQVR----GVPWNFTFNVKFYPPDPAQLTEDITRYYLCLQLRQDIVAGRLPCS 112
Query: 132 VNTAAQLGAYAIQSELGDYDPYKHTAGYVSEYRFVPDQKEELEEAIERIHKTLMGQIPSE 191
T A LG+Y IQSELGDYDP H YVS+++ P+Q +ELEE + +HK+ P++
Sbjct: 113 FATLALLGSYTIQSELGDYDPELHGVDYVSDFKLAPNQTKELEEKVMELHKSYRSMTPAQ 172
Query: 192 AELNYLRTAKSLEMYGVDLHPVYGENKSEYFLGLTPVGVVVYKNKKQVGKYFWPRITKVH 251
A+L +L AK L MYGVDLH + LG+ G++VYK+K ++ ++ WP++ K+
Sbjct: 173 ADLEFLENAKKLSMYGVDLHKAKDLEGVDIILGVCSSGLLVYKDKLRINRFPWPKVLKIS 232
Query: 252 FKETQF--ELRVLGKDCNETSFFFEARSKTACKHLWKCSVEHHTFFRMPENESNSLSRKL 309
+K + F ++R ++ E++ F+ S A K LWK VEHHTFFR+ + +
Sbjct: 233 YKRSSFFIKIRPGEQEQYESTIGFKLPSYRAAKKLWKVCVEHHTFFRLTSTD----TIPK 288
Query: 310 SKFGSIRYKHRYSGRTALQMSRDLSIQLPRPDQNVTRSRSKTYPKRIAQTQPAES----- 364
SKF ++ K RYSGRT Q +R S + RP + R+ SK + + +S
Sbjct: 289 SKFLALGSKFRYSGRTQAQ-TRQASALIDRPAPHFERTASKRASRSLDGAAAVDSADRSP 347
Query: 365 --NSISRITANM--ENGENEGTI-KIIAPSPVKSFKKA--KNENSPDTQ 406
S IT E G + + K + P K KA K E+ P Q
Sbjct: 348 RPTSAPAITQGQVAEGGVLDASAKKTVVPKAQKETVKAEVKKEDEPPEQ 396
>gi|4758274 erythrocyte membrane protein band 4.1 (elliptocytosis 1,
RH-linked) isoform 3 [Homo sapiens]
Length = 588
Score = 253 bits (647), Expect = 3e-67
Identities = 152/409 (37%), Positives = 222/409 (54%), Gaps = 28/409 (6%)
Query: 12 YCEVLLLDESKLTLTTQQQGIKKSTKGSVVLDHVFHHVNLVEIDYFGLRYCDRSHQTYWL 71
+C+V LLD+ T + ++K KG +L V H+NL+E DYFGL D + WL
Sbjct: 2 HCKVSLLDD-----TVYECVVEKHAKGQDLLKRVCEHLNLLEEDYFGLAIWDNATSKTWL 56
Query: 72 DPAKTLAEHKELINTGPPYTLYFGIKFYAEDPCKLKEEITRYQFFLQVKQDVLQGRLPCP 131
D AK + + G P+ F +KFY DP +L E+ITRY LQ++QD++ GRLPC
Sbjct: 57 DSAKEIKKQVR----GVPWNFTFNVKFYPPDPAQLTEDITRYYLCLQLRQDIVAGRLPCS 112
Query: 132 VNTAAQLGAYAIQSELGDYDPYKHTAGYVSEYRFVPDQKEELEEAIERIHKTLMGQIPSE 191
T A LG+Y IQSELGDYDP H YVS+++ P+Q +ELEE + +HK+ P++
Sbjct: 113 FATLALLGSYTIQSELGDYDPELHGVDYVSDFKLAPNQTKELEEKVMELHKSYRSMTPAQ 172
Query: 192 AELNYLRTAKSLEMYGVDLHPVYGENKSEYFLGLTPVGVVVYKNKKQVGKYFWPRITKVH 251
A+L +L AK L MYGVDLH + LG+ G++VYK+K ++ ++ WP++ K+
Sbjct: 173 ADLEFLENAKKLSMYGVDLHKAKDLEGVDIILGVCSSGLLVYKDKLRINRFPWPKVLKIS 232
Query: 252 FKETQF--ELRVLGKDCNETSFFFEARSKTACKHLWKCSVEHHTFFRMPENESNSLSRKL 309
+K + F ++R ++ E++ F+ S A K LWK VEHHTFFR+ + +
Sbjct: 233 YKRSSFFIKIRPGEQEQYESTIGFKLPSYRAAKKLWKVCVEHHTFFRLTSTD----TIPK 288
Query: 310 SKFGSIRYKHRYSGRTALQMSRDLSIQLPRPDQNVTRSRSKTYPKRIAQTQPAES----- 364
SKF ++ K RYSGRT Q +R S + RP + R+ SK + + +S
Sbjct: 289 SKFLALGSKFRYSGRTQAQ-TRQASALIDRPAPHFERTASKRASRSLDGAAAVDSADRSP 347
Query: 365 --NSISRITANM--ENGENEGTI-KIIAPSPVKSFKKA--KNENSPDTQ 406
S IT E G + + K + P K KA K E+ P Q
Sbjct: 348 RPTSAPAITQGQVAEGGVLDASAKKTVVPKAQKETVKAEVKKEDEPPEQ 396
>gi|94721308 FERM domain containing 5 isoform 2 [Homo sapiens]
Length = 570
Score = 253 bits (647), Expect = 3e-67
Identities = 140/349 (40%), Positives = 207/349 (59%), Gaps = 23/349 (6%)
Query: 6 AVPEEFYCEVLLLDESKLTLTTQQQGIKKSTKGSVVLDHVFHHVNLVEIDYFGLRYCDRS 65
++ E+ C V LLD+S+ T T I++ KG + D + HH+NL+E DYFG+R+ D
Sbjct: 12 SLEREYSCTVRLLDDSEYTCT-----IQRDAKGQYLFDLLCHHLNLLEKDYFGIRFVDPD 66
Query: 66 HQTYWLDPAKTLAEHKELINTGPPYTLYFGIKFYAEDPCKLKEEITRYQFFLQVKQDVLQ 125
Q +WL+ K++ + + + PP+T+ F +KFY DP LKEEITRY FLQ+K+D+
Sbjct: 67 KQRHWLEFTKSVVKQ---LRSQPPFTMCFRVKFYPADPAALKEEITRYLVFLQIKRDLYH 123
Query: 126 GRLPCPVNTAAQLGAYAIQSELGDYDPYKHTAGYVSEYRFVPDQKEELEEAIERIHKT-L 184
GRL C + AA L AY +Q+E+GDYD KH GY S+++F P E+LE I IHKT L
Sbjct: 124 GRLLCKTSDAALLAAYILQAEIGDYDSGKHPEGYSSKFQFFPKHSEKLERKIAEIHKTEL 183
Query: 185 MGQIPSEAELNYLRTAKSLEMYGVDLHPVYGENKSEYFLGLTPVGVVVYKNKKQVGKYFW 244
GQ P+ +ELN+LR A++LE YGVD HP + + FL TP G VV + K+V W
Sbjct: 184 SGQTPATSELNFLRKAQTLETYGVDPHPCKDVSGNAAFLAFTPFGFVVLQGNKRVHFIKW 243
Query: 245 PRITKVHFKETQFELRVLGKDCNETSFFFEARSKTACKHLWKCSVEHHTFFRMPEN---- 300
+TK+ F+ F L V K+ + + A + ACKHLWKC +E+ F+++ ++
Sbjct: 244 NEVTKLKFEGKTFYLYVSQKEEKKIILTYFAPTPEACKHLWKCGIENQAFYKLEKSSQVR 303
Query: 301 --ESNSLSRKLSKFGSIRYKHRYSGRTALQMSRDLSIQLPRPDQNVTRS 347
S++L K S+F RYSGR A ++ + S ++ R + R+
Sbjct: 304 TVSSSNLFFKGSRF-------RYSGRVAKEV-MESSAKIKREPPEIHRA 344
>gi|117500790 FERM domain containing 3 [Homo sapiens]
Length = 597
Score = 251 bits (642), Expect = 1e-66
Identities = 164/494 (33%), Positives = 255/494 (51%), Gaps = 32/494 (6%)
Query: 6 AVPEEFYCEVLLLDESKLTLTTQQQGIKKSTKGSVVLDHVFHHVNLVEIDYFGLRYCDRS 65
++ +E C + LLD+S+++ Q++ TKG ++DH+ ++ +L+E DYFG+RY D
Sbjct: 27 SLSQEMRCTIRLLDDSEISCHIQRE-----TKGQFLIDHICNYYSLLEKDYFGIRYVDPE 81
Query: 66 HQTYWLDPAKTLAEHKELINTGPPYTLYFGIKFYAEDPCKLKEEITRYQFFLQVKQDVLQ 125
Q +WL+P K++ + + T PPYT+ F +KFY +P K+KEE+TRY +LQ+K+D+
Sbjct: 82 KQRHWLEPNKSIFKQ---MKTHPPYTMCFRVKFYPHEPLKIKEELTRYLLYLQIKRDIFH 138
Query: 126 GRLPCPVNTAAQLGAYAIQSELGDYDPYKHTAGYVSEYRFVPDQKEELEEAIERIHKT-L 184
GRL C + AA LGA +Q+ELGDYDP +H Y+SE+ P Q ++LE I IHK L
Sbjct: 139 GRLLCSFSDAAYLGACIVQAELGDYDPDEHPENYISEFEIFPKQSQKLERKIVEIHKNEL 198
Query: 185 MGQIPSEAELNYLRTAKSLEMYGVDLHPVYGENKSEYFLGLTPVGVVVYKNKKQVGKYFW 244
GQ P AE N L A +LE YGVD HP + FLG T G VV++ K++ W
Sbjct: 199 RGQSPPVAEFNLLLKAHTLETYGVDPHPCKDSTGTTTFLGFTAAGFVVFQGNKRIHLIKW 258
Query: 245 PRITKVHFKETQFELRVLGKDCNETSFFFEARSKTACKHLWKCSVEHHTFFRMPE-NESN 303
P + K+ F+ F + K+ + F + ACKHLWKC VE+ F++ + ++
Sbjct: 259 PDVCKLKFEGKTFYVIGTQKE-KKAMLAFHTSTPAACKHLWKCGVENQAFYKYAKSSQIK 317
Query: 304 SLSRKLSKFGSIRYKHRYSGRTALQMSRDLS-IQLPRPD---QNVTRSRS--KTYPKRIA 357
++S F R+ RYSG+ A ++ S IQ P+ N+T+SRS + I
Sbjct: 318 TVSSSKIFFKGSRF--RYSGKVAKEVVEASSKIQREPPEVHRANITQSRSSHSLNKQLII 375
Query: 358 QTQPAESNSISRITANMENGENEG---------TIKIIAPSPVKSFKKAKNENSPDTQRS 408
+P + S E EG + +I+ SPVK+ ++ ++ S + +
Sbjct: 376 NMEPLQPLLPSPSEQEEELPLGEGVPLPKEENISAPLISSSPVKAAREYEDPPSEEEDKI 435
Query: 409 KSHAPWEEN---GPQSGLYNSPSDRTKSPKFPYTRRRNPSCGSDNDSVQPVRR-RKAHNS 464
K P + L +P D + R D DS + + A
Sbjct: 436 KEEPLTISELVYNPSASLLPTPVDDDEIDMLFDCPSRLELEREDTDSFEDLEADENAFLI 495
Query: 465 GEDSDLKQRRRSRS 478
E+ +LK+ RR+ S
Sbjct: 496 AEEEELKEARRALS 509
>gi|207113199 erythrocyte membrane protein band 4.1-like 2 isoform b
[Homo sapiens]
Length = 673
Score = 246 bits (629), Expect = 4e-65
Identities = 135/340 (39%), Positives = 202/340 (59%), Gaps = 16/340 (4%)
Query: 13 CEVLLLDESKLTLTTQQQGIKKSTKGSVVLDHVFHHVNLVEIDYFGLRYCDRSHQTYWLD 72
C+V LLD ++ + ++K KG V+ D V H+NL+E DYFGL + + Q WLD
Sbjct: 220 CKVTLLDGTEYSCD-----LEKHAKGQVLFDKVCEHLNLLEKDYFGLLFQESPEQKNWLD 274
Query: 73 PAKTLAEHKELINTGPPYTLYFGIKFYAEDPCKLKEEITRYQFFLQVKQDVLQGRLPCPV 132
PAK + ++L N P+ F +KFY DP +L E+ITRY LQ++QD+ GRLPC
Sbjct: 275 PAKEIK--RQLRNL--PWLFTFNVKFYPPDPSQLTEDITRYFLCLQLRQDIASGRLPCSF 330
Query: 133 NTAAQLGAYAIQSELGDYDPYKHTAGYVSEYRFVPDQKEELEEAIERIHKTLMGQIPSEA 192
T A LG+Y +Q+ELGDYDP +H + +SE++F P Q +ELEE + +HKT G P++A
Sbjct: 331 VTHALLGSYTLQAELGDYDPEEHGSIDLSEFQFAPTQTKELEEKVAELHKTHRGLSPAQA 390
Query: 193 ELNYLRTAKSLEMYGVDLHPVYGENKSEYFLGLTPVGVVVYKNKKQVGKYFWPRITKVHF 252
+ +L AK L MYGVDLH + LG+ G+++YK++ ++ ++ WP+I K+ +
Sbjct: 391 DSQFLENAKRLSMYGVDLHHAKDSEGVDIKLGVCANGLLIYKDRLRINRFAWPKILKISY 450
Query: 253 KETQFELRVLGKDCN--ETSFFFEARSKTACKHLWKCSVEHHTFFRMPENESNSLSRKLS 310
K + F ++V + E++ F+ + A K LWK VEHHTF+R+ E +
Sbjct: 451 KRSNFYIKVRPAELEQFESTIGFKLPNHRAAKRLWKVCVEHHTFYRLVSPE----QPPKA 506
Query: 311 KFGSIRYKHRYSGRTALQMSRDLSIQLPRPDQNVTRSRSK 350
KF ++ K RYSGRT Q +R S + RP + R+ SK
Sbjct: 507 KFLTLGSKFRYSGRTQAQ-TRQASTLIDRPAPHFERTSSK 545
>gi|207113195 erythrocyte membrane protein band 4.1-like 2 isoform b
[Homo sapiens]
Length = 673
Score = 246 bits (629), Expect = 4e-65
Identities = 135/340 (39%), Positives = 202/340 (59%), Gaps = 16/340 (4%)
Query: 13 CEVLLLDESKLTLTTQQQGIKKSTKGSVVLDHVFHHVNLVEIDYFGLRYCDRSHQTYWLD 72
C+V LLD ++ + ++K KG V+ D V H+NL+E DYFGL + + Q WLD
Sbjct: 220 CKVTLLDGTEYSCD-----LEKHAKGQVLFDKVCEHLNLLEKDYFGLLFQESPEQKNWLD 274
Query: 73 PAKTLAEHKELINTGPPYTLYFGIKFYAEDPCKLKEEITRYQFFLQVKQDVLQGRLPCPV 132
PAK + ++L N P+ F +KFY DP +L E+ITRY LQ++QD+ GRLPC
Sbjct: 275 PAKEIK--RQLRNL--PWLFTFNVKFYPPDPSQLTEDITRYFLCLQLRQDIASGRLPCSF 330
Query: 133 NTAAQLGAYAIQSELGDYDPYKHTAGYVSEYRFVPDQKEELEEAIERIHKTLMGQIPSEA 192
T A LG+Y +Q+ELGDYDP +H + +SE++F P Q +ELEE + +HKT G P++A
Sbjct: 331 VTHALLGSYTLQAELGDYDPEEHGSIDLSEFQFAPTQTKELEEKVAELHKTHRGLSPAQA 390
Query: 193 ELNYLRTAKSLEMYGVDLHPVYGENKSEYFLGLTPVGVVVYKNKKQVGKYFWPRITKVHF 252
+ +L AK L MYGVDLH + LG+ G+++YK++ ++ ++ WP+I K+ +
Sbjct: 391 DSQFLENAKRLSMYGVDLHHAKDSEGVDIKLGVCANGLLIYKDRLRINRFAWPKILKISY 450
Query: 253 KETQFELRVLGKDCN--ETSFFFEARSKTACKHLWKCSVEHHTFFRMPENESNSLSRKLS 310
K + F ++V + E++ F+ + A K LWK VEHHTF+R+ E +
Sbjct: 451 KRSNFYIKVRPAELEQFESTIGFKLPNHRAAKRLWKVCVEHHTFYRLVSPE----QPPKA 506
Query: 311 KFGSIRYKHRYSGRTALQMSRDLSIQLPRPDQNVTRSRSK 350
KF ++ K RYSGRT Q +R S + RP + R+ SK
Sbjct: 507 KFLTLGSKFRYSGRTQAQ-TRQASTLIDRPAPHFERTSSK 545
>gi|4503579 erythrocyte membrane protein band 4.1-like 2 isoform a
[Homo sapiens]
Length = 1005
Score = 246 bits (629), Expect = 4e-65
Identities = 135/340 (39%), Positives = 202/340 (59%), Gaps = 16/340 (4%)
Query: 13 CEVLLLDESKLTLTTQQQGIKKSTKGSVVLDHVFHHVNLVEIDYFGLRYCDRSHQTYWLD 72
C+V LLD ++ + ++K KG V+ D V H+NL+E DYFGL + + Q WLD
Sbjct: 220 CKVTLLDGTEYSCD-----LEKHAKGQVLFDKVCEHLNLLEKDYFGLLFQESPEQKNWLD 274
Query: 73 PAKTLAEHKELINTGPPYTLYFGIKFYAEDPCKLKEEITRYQFFLQVKQDVLQGRLPCPV 132
PAK + ++L N P+ F +KFY DP +L E+ITRY LQ++QD+ GRLPC
Sbjct: 275 PAKEIK--RQLRNL--PWLFTFNVKFYPPDPSQLTEDITRYFLCLQLRQDIASGRLPCSF 330
Query: 133 NTAAQLGAYAIQSELGDYDPYKHTAGYVSEYRFVPDQKEELEEAIERIHKTLMGQIPSEA 192
T A LG+Y +Q+ELGDYDP +H + +SE++F P Q +ELEE + +HKT G P++A
Sbjct: 331 VTHALLGSYTLQAELGDYDPEEHGSIDLSEFQFAPTQTKELEEKVAELHKTHRGLSPAQA 390
Query: 193 ELNYLRTAKSLEMYGVDLHPVYGENKSEYFLGLTPVGVVVYKNKKQVGKYFWPRITKVHF 252
+ +L AK L MYGVDLH + LG+ G+++YK++ ++ ++ WP+I K+ +
Sbjct: 391 DSQFLENAKRLSMYGVDLHHAKDSEGVDIKLGVCANGLLIYKDRLRINRFAWPKILKISY 450
Query: 253 KETQFELRVLGKDCN--ETSFFFEARSKTACKHLWKCSVEHHTFFRMPENESNSLSRKLS 310
K + F ++V + E++ F+ + A K LWK VEHHTF+R+ E +
Sbjct: 451 KRSNFYIKVRPAELEQFESTIGFKLPNHRAAKRLWKVCVEHHTFYRLVSPE----QPPKA 506
Query: 311 KFGSIRYKHRYSGRTALQMSRDLSIQLPRPDQNVTRSRSK 350
KF ++ K RYSGRT Q +R S + RP + R+ SK
Sbjct: 507 KFLTLGSKFRYSGRTQAQ-TRQASTLIDRPAPHFERTSSK 545
>gi|42716289 erythrocyte membrane protein band 4.1 (elliptocytosis
1, RH-linked) isoform 1 [Homo sapiens]
Length = 775
Score = 221 bits (562), Expect = 2e-57
Identities = 131/351 (37%), Positives = 191/351 (54%), Gaps = 23/351 (6%)
Query: 70 WLDPAKTLAEHKELINTGPPYTLYFGIKFYAEDPCKLKEEITRYQFFLQVKQDVLQGRLP 129
WLD AK + + G P+ F +KFY DP +L E+ITRY LQ++QD++ GRLP
Sbjct: 229 WLDSAKEIKKQVR----GVPWNFTFNVKFYPPDPAQLTEDITRYYLCLQLRQDIVAGRLP 284
Query: 130 CPVNTAAQLGAYAIQSELGDYDPYKHTAGYVSEYRFVPDQKEELEEAIERIHKTLMGQIP 189
C T A LG+Y IQSELGDYDP H YVS+++ P+Q +ELEE + +HK+ P
Sbjct: 285 CSFATLALLGSYTIQSELGDYDPELHGVDYVSDFKLAPNQTKELEEKVMELHKSYRSMTP 344
Query: 190 SEAELNYLRTAKSLEMYGVDLHPVYGENKSEYFLGLTPVGVVVYKNKKQVGKYFWPRITK 249
++A+L +L AK L MYGVDLH + LG+ G++VYK+K ++ ++ WP++ K
Sbjct: 345 AQADLEFLENAKKLSMYGVDLHKAKDLEGVDIILGVCSSGLLVYKDKLRINRFPWPKVLK 404
Query: 250 VHFKETQF--ELRVLGKDCNETSFFFEARSKTACKHLWKCSVEHHTFFRMPENESNSLSR 307
+ +K + F ++R ++ E++ F+ S A K LWK VEHHTFFR+ + +
Sbjct: 405 ISYKRSSFFIKIRPGEQEQYESTIGFKLPSYRAAKKLWKVCVEHHTFFRLTSTD----TI 460
Query: 308 KLSKFGSIRYKHRYSGRTALQMSRDLSIQLPRPDQNVTRSRSKTYPKRIAQTQPAES--- 364
SKF ++ K RYSGRT Q +R S + RP + R+ SK + + +S
Sbjct: 461 PKSKFLALGSKFRYSGRTQAQ-TRQASALIDRPAPHFERTASKRASRSLDGAAAVDSADR 519
Query: 365 ----NSISRITANM--ENGENEGTI-KIIAPSPVKSFKKA--KNENSPDTQ 406
S IT E G + + K + P K KA K E+ P Q
Sbjct: 520 SPRPTSAPAITQGQVAEGGVLDASAKKTVVPKAQKETVKAEVKKEDEPPEQ 570
>gi|223941876 protein tyrosine phosphatase, non-receptor type 3
isoform 1 [Homo sapiens]
Length = 913
Score = 196 bits (499), Expect = 5e-50
Identities = 143/484 (29%), Positives = 225/484 (46%), Gaps = 43/484 (8%)
Query: 10 EFYCEVLLLDESKLTLTTQQQGIKKSTKGSVVLDHVFHHVNLVEIDYFGLRYCDRSHQT- 68
E C + LD Q + K G V+LD V +H+ + E +YFGL++ D S +
Sbjct: 28 EVICSIHFLDG-----VVQTFKVTKQDTGQVLLDMVHNHLGVTEKEYFGLQHDDDSVDSP 82
Query: 69 YWLDPAKTLAEHKELINTGPPYTLYFGIKFYAEDPCKLKEEITRYQFFLQVKQDVLQGRL 128
WL+ +K + ++ + G P TL+F ++F+ DP L++E TR+ +FLQ+K D+ +GRL
Sbjct: 83 RWLEASKAI---RKQLKGGFPCTLHFRVRFFIPDPNTLQQEQTRHLYFLQLKMDICEGRL 139
Query: 129 PCPVNTAAQLGAYAIQSELGDYDPYKHTAGYVSEYRFVPDQKEELEEAIERIHKTLMGQI 188
CP+N+A L +YA+QS GDY+ H GY+S+ F+PDQ E+ +E +H+ G
Sbjct: 140 TCPLNSAVVLASYAVQSHFGDYNSSIHHPGYLSDSHFIPDQNEDFLTKVESLHEQHSGLK 199
Query: 189 PSEAELNYLRTAKSLEMYGVDLHPVYGENKSEYFLGLTPVGVVVYKNKKQVGKYFWPRIT 248
SEAE Y+ A++L+ YGV+LH + + +G+ GV VY+ Y W I
Sbjct: 200 QSEAESCYINIARTLDFYGVELHSGRDLHNLDLMIGIASAGVAVYRKYICTSFYPWVNIL 259
Query: 249 KVHFKETQFELRVLGK--DCNETSFFFEARSKTACKHLWKCSVEHHTFF---RMPENESN 303
K+ FK +F + K + E F + +CK+LWK VEHHTFF ++ E N
Sbjct: 260 KISFKRKKFFIHQRQKQAESREHIVAFNMLNYRSCKNLWKSCVEHHTFFQAKKLLPQEKN 319
Query: 304 SL-------SRKLSKFGSIRYKHRYSGRTALQ--MSRDLSIQLPRPDQNVTRSRSKTYPK 354
L SR K + +Y + G M R LS++ +K+ P
Sbjct: 320 VLSQYWTMGSRNTKKSVNNQYCKKVIGGMVWNPAMRRSLSVE---------HLETKSLPS 370
Query: 355 RIAQTQPAESNSISRIT------ANMENGENEGTIKIIAPSPVKSFKKAKNENSPDTQRS 408
R P + R ++ +N NE T ++K + D++ S
Sbjct: 371 RSPPITPNWRSPRLRHEIRKPRHSSADNLANEMTYITETEDVFYTYKGSLAPQDSDSEVS 430
Query: 409 KSHAPWE----ENGPQSGLYNSPSDRTKSPKFPYTRRRNPSCGSDNDSVQPVRRRKAHNS 464
++ +P + EN P S + SP +P G D + R S
Sbjct: 431 QNRSPHQESLSENNPAQSYLTQKSSSSVSPSSNAPGSCSPD-GVDQQLLDDFHRVTKGGS 489
Query: 465 GEDS 468
ED+
Sbjct: 490 TEDA 493
>gi|223941879 protein tyrosine phosphatase, non-receptor type 3
isoform 2 [Homo sapiens]
Length = 868
Score = 194 bits (494), Expect = 2e-49
Identities = 109/304 (35%), Positives = 168/304 (55%), Gaps = 14/304 (4%)
Query: 10 EFYCEVLLLDESKLTLTTQQQGIKKSTKGSVVLDHVFHHVNLVEIDYFGLRYCDRSHQT- 68
E C + LD Q + K G V+LD V +H+ + E +YFGL++ D S +
Sbjct: 28 EVICSIHFLDG-----VVQTFKVTKQDTGQVLLDMVHNHLGVTEKEYFGLQHDDDSVDSP 82
Query: 69 YWLDPAKTLAEHKELINTGPPYTLYFGIKFYAEDPCKLKEEITRYQFFLQVKQDVLQGRL 128
WL+ +K + ++ + G P TL+F ++F+ DP L++E TR+ +FLQ+K D+ +GRL
Sbjct: 83 RWLEASKAI---RKQLKGGFPCTLHFRVRFFIPDPNTLQQEQTRHLYFLQLKMDICEGRL 139
Query: 129 PCPVNTAAQLGAYAIQSELGDYDPYKHTAGYVSEYRFVPDQKEELEEAIERIHKTLMGQI 188
CP+N+A L +YA+QS GDY+ H GY+S+ F+PDQ E+ +E +H+ G
Sbjct: 140 TCPLNSAVVLASYAVQSHFGDYNSSIHHPGYLSDSHFIPDQNEDFLTKVESLHEQHSGLK 199
Query: 189 PSEAELNYLRTAKSLEMYGVDLHPVYGENKSEYFLGLTPVGVVVYKNKKQVGKYFWPRIT 248
SEAE Y+ A++L+ YGV+LH + + +G+ GV VY+ Y W I
Sbjct: 200 QSEAESCYINIARTLDFYGVELHSGRDLHNLDLMIGIASAGVAVYRKYICTSFYPWVNIL 259
Query: 249 KVHFKETQFELRVLGK--DCNETSFFFEARSKTACKHLWKCSVEHHTFF---RMPENESN 303
K+ FK +F + K + E F + +CK+LWK VEHHTFF ++ E N
Sbjct: 260 KISFKRKKFFIHQRQKQAESREHIVAFNMLNYRSCKNLWKSCVEHHTFFQAKKLLPQEKN 319
Query: 304 SLSR 307
LS+
Sbjct: 320 VLSQ 323
>gi|5031633 FERM, RhoGEF, and pleckstrin domain protein 1 isoform 1
[Homo sapiens]
Length = 1045
Score = 189 bits (480), Expect = 7e-48
Identities = 119/355 (33%), Positives = 185/355 (52%), Gaps = 16/355 (4%)
Query: 14 EVLLLDESKLTLTTQQQGIKKSTKGSVVLDHVFHHVNLVEIDYFGLRYCDRSHQTYWLDP 73
++ +LD+++ Q+ G V+LD V +H+NLVE DYFGL + D T WLD
Sbjct: 43 KIQMLDDTQEAFEVPQRA-----PGKVLLDAVCNHLNLVEGDYFGLEFPDHKKITVWLDL 97
Query: 74 AKTLAEHKELINTGPPYTLYFGIKFYAEDPCKLKEEITRYQFFLQVKQDVLQGRLPCPVN 133
K + + I + F +KF+ D +L+EE+TRY F LQVKQD+ QGRL C
Sbjct: 98 LKPIVKQ---IRRPKHVVVKFVVKFFPPDHTQLQEELTRYLFALQVKQDLAQGRLTCNDT 154
Query: 134 TAAQLGAYAIQSELGDYDPYKHTAGYVSEYRFVPDQKEELEEAIERIHKTLMGQIPSEAE 193
+AA L ++ +QSE+GD+D ++++ +++P Q++ LE+ I H +GQ P+E++
Sbjct: 155 SAALLISHIVQSEIGDFDEALDRE-HLAKNKYIP-QQDALEDKIVEFHHNHIGQTPAESD 212
Query: 194 LNYLRTAKSLEMYGVDLHPVYGENKSEYFLGLTPVGVVVYKNKKQVGKYFWPRITKVHFK 253
L A+ LEMYG+ LHP ++ L + G++V++ ++ + W ++ K+ FK
Sbjct: 213 FQLLEIARRLEMYGIRLHPAKDREGTKINLAVANTGILVFQGFTKINAFNWAKVRKLSFK 272
Query: 254 ETQF--ELRVLGKDCNETSFFFEARSKTACKHLWKCSVEHHTFFRMPENESNSLSRKLSK 311
+F +LR + + F S+ CK WK VEHH FFR+ E L
Sbjct: 273 RKRFLIKLRPDANSAYQDTLEFLMASRDFCKSFWKICVEHHAFFRLFEEPKPKPKPVLFS 332
Query: 312 FGSIRYKHRYSGRTALQMSRDLSIQLPRPDQNVTRSRSKTYPKRIAQTQPAESNS 366
GS R+SGRT Q+ D + R SK + R +QP E NS
Sbjct: 333 RGS---SFRFSGRTQKQV-LDYVKEGGHKKVQFERKHSKIHSIRSLASQPTELNS 383
>gi|7662310 FERM, RhoGEF and pleckstrin domain protein 2 [Homo
sapiens]
Length = 1054
Score = 174 bits (441), Expect = 2e-43
Identities = 134/459 (29%), Positives = 210/459 (45%), Gaps = 33/459 (7%)
Query: 9 EEFYCEVLLLDESKLTLTTQQQGIKKSTKGSVVLDHVFHHVNLVEIDYFGLRYCDRSHQT 68
+ + V LLD T + I+ G V+L V+ +NLVE DYFG+ + +
Sbjct: 42 KHLHLRVKLLDN-----TMEIFDIEPKCDGQVLLTQVWKRLNLVECDYFGMEFQNTQSYW 96
Query: 69 YWLDPAKTLAEHKELINTGPPYTLYFGIKFYAEDPCKLKEEITRYQFFLQVKQDVLQGRL 128
WL+P K + I L +KF+ DP +L+EE TRY F LQ+K+D+L+ RL
Sbjct: 97 IWLEPMKPIIRQ---IRRPKNVVLRLAVKFFPPDPGQLQEEYTRYLFALQLKRDLLEERL 153
Query: 129 PCPVNTAAQLGAYAIQSELGDYDPYKHTAGYVSEYRFVPDQKEELEEAIERIHKTLMGQI 188
C TAA L ++ +QSE+GDYD ++ ++P Q+ LE+ +E H+ +GQ
Sbjct: 154 TCADTTAALLTSHLLQSEIGDYDETLDRE-HLKVNEYLPGQQHCLEKILE-FHQKHVGQT 211
Query: 189 PSEAELNYLRTAKSLEMYGVDLHPVYGENKSEYFLGLTPVGVVVYKNKKQVGKYFWPRIT 248
P+E++ L A+ LEMYG+ H ++ L ++ +GV+V++ ++ + W ++
Sbjct: 212 PAESDFQVLEIARKLEMYGIRFHMASDREGTKIQLAVSHMGVLVFQGTTKINTFNWSKVR 271
Query: 249 KVHFKETQFELR----VLGKDCNETSFFFEARSKTACKHLWKCSVEHHTFFRMPENESNS 304
K+ FK +F ++ V G + F +R + CK+ WK VE+HTFFR+ +
Sbjct: 272 KLSFKRKRFLIKLHPEVHGPYQDTLEFLLGSRDE--CKNFWKICVEYHTFFRLLDQPKPK 329
Query: 305 LSRKLSKFGSIRYKHRYSGRTALQMSRDLSIQLPRPDQNVTRSRSKTYPKRIAQTQPAES 364
GS RYSGRT Q+ D R SKT+ A T
Sbjct: 330 AKAVFFSRGS---SFRYSGRTQKQLV-DYFKDSGMKRIPYERRHSKTHTSVRALTADLPK 385
Query: 365 NSIS-------RITANMENGENEGTIKIIAPSPVKSFKKAKNE-NSPDTQRSKSHAPWEE 416
SIS + + N + + PS + FK + + P KS A
Sbjct: 386 QSISFPEGLRTPASPSSANAFYSLSPSTLVPSGLPEFKDSSSSLTDPQVSYVKSPAAERR 445
Query: 417 NGPQSGLYNSPSDRTKSPKFPYTRRRNPSCGSDNDSVQP 455
+G +G ++PS + P P G S QP
Sbjct: 446 SGAVAGGPDTPSAQPLGPP-----ALQPGPGLSTKSPQP 479
>gi|34916000 FERM domain containing 7 [Homo sapiens]
Length = 714
Score = 172 bits (436), Expect = 9e-43
Identities = 105/324 (32%), Positives = 168/324 (51%), Gaps = 23/324 (7%)
Query: 12 YCEVLLLDESKLTLTTQQQGIKKSTKGSVVLDHVFHHVNLVEIDYFGLRYCDRSHQTYWL 71
+ +V LD+S+ Q+ + G + + H+NL E +YFGL +C S WL
Sbjct: 3 HLKVQFLDDSQKIFVVDQK-----SSGKALFNLSCSHLNLAEKEYFGLEFCSHSGNNVWL 57
Query: 72 DPAKTLAEHKELINTGPPYTLYFGIKFYAEDPCKLKEEITRYQFFLQVKQDVLQGRLPCP 131
+ K + + + F +KF+ DP L+EE+TRY F LQ+K+D+ GRLPC
Sbjct: 58 ELLKPITKQ---VKNPKEIVFKFMVKFFPVDPGHLREELTRYLFTLQIKKDLALGRLPCS 114
Query: 132 VNTAAQLGAYAIQSELGDYDPYKHTAGYVSEYRFVPDQKEELEEAIERIHKTLMGQIPSE 191
N A + ++ +QSELGD+ + ++++ R++P+Q + LE I H+ +G+ P+E
Sbjct: 115 DNCTALMVSHILQSELGDFHE-ETDRKHLAQTRYLPNQ-DCLEGKIMHFHQKHIGRSPAE 172
Query: 192 AELNYLRTAKSLEMYGVDLHPVYGENKSEYFLGLTPVGVVVYKNKKQVGKYFWPRITKVH 251
+++ L A+ L+MYG+ HP + L + +GV+V + ++ + W +I K+
Sbjct: 173 SDILLLDIARKLDMYGIRPHPASDGEGMQIHLAVAHMGVLVLRGNTKINTFNWAKIRKLS 232
Query: 252 FKETQFELR------VLGKDCNETSFFFEARSKTACKHLWKCSVEHHTFFRMPENESNSL 305
FK F ++ VL KD E F S+ ACK WK VE+H FFR+ E +
Sbjct: 233 FKRKHFLIKLHANILVLCKDTLE----FTMASRDACKAFWKTCVEYHAFFRLSEEPKSKP 288
Query: 306 SRKLSKFGSIRYKHRYSGRTALQM 329
L GS RYSGRT Q+
Sbjct: 289 KTLLCSKGS---SFRYSGRTQRQL 309
>gi|150418005 protein tyrosine phosphatase, non-receptor type 21
[Homo sapiens]
Length = 1174
Score = 138 bits (347), Expect = 2e-32
Identities = 77/268 (28%), Positives = 140/268 (52%), Gaps = 14/268 (5%)
Query: 38 GSVVLDHVFHHVNLVEIDYFGLRYCDRSHQTYWLDPAKTLAEHKELINTGPPYTLYFGIK 97
G L+ V + L E+ YF L Y ++ +Q W+D K L + + P T+YFG+
Sbjct: 45 GQESLEAVAQRLELREVTYFSLWYYNKQNQRRWVDLEKPLKKQLDKYALEP--TVYFGVV 102
Query: 98 FYAEDPCKLKEEITRYQFFLQVKQDVLQGRLPCPVNTAAQLGAYAIQSELGDYDPYKHTA 157
FY +L++EITRYQ++LQ+K+D+L+G +PC + A QL A+Q++ GD+D Y+ +
Sbjct: 103 FYVPSVSQLQQEITRYQYYLQLKKDILEGSIPCTLEQAIQLAGLAVQADFGDFDQYE-SQ 161
Query: 158 GYVSEYRFVP-----DQK--EELEEAIERIHKTLMGQIPSEAELNYLRTAKSLEMYGVDL 210
++ ++ P D+K EE + + +H+ G +AE+ Y++ + ++ YG +
Sbjct: 162 DFLQKFALFPVGWLQDEKVLEEATQKVALLHQKYRGLTAPDAEMLYMQEVERMDGYGEES 221
Query: 211 HPVYGENKSEYFLGLTPVGVVV-YKNKKQVGKYFWPRITKVHFKETQFELRVLGKDCNET 269
+P S+ +G G+ V +KN + + W I + ++ F L + K E
Sbjct: 222 YPAKDSQGSDISIGACLEGIFVKHKNGRHPVVFRWHDIANMSHNKSFFALELANK---EE 278
Query: 270 SFFFEARSKTACKHLWKCSVEHHTFFRM 297
+ F+ K++W+ V H F+R+
Sbjct: 279 TIQFQTEDMETAKYIWRLCVARHKFYRL 306
>gi|223941882 protein tyrosine phosphatase, non-receptor type 3
isoform 3 [Homo sapiens]
Length = 782
Score = 136 bits (342), Expect = 7e-32
Identities = 105/371 (28%), Positives = 162/371 (43%), Gaps = 34/371 (9%)
Query: 122 DVLQGRLPCPVNTAAQLGAYAIQSELGDYDPYKHTAGYVSEYRFVPDQKEELEEAIERIH 181
D+ +GRL CP+N+A L +YA+QS GDY+ H GY+S+ F+PDQ E+ +E +H
Sbjct: 2 DICEGRLTCPLNSAVVLASYAVQSHFGDYNSSIHHPGYLSDSHFIPDQNEDFLTKVESLH 61
Query: 182 KTLMGQIPSEAELNYLRTAKSLEMYGVDLHPVYGENKSEYFLGLTPVGVVVYKNKKQVGK 241
+ G SEAE Y+ A++L+ YGV+LH + + +G+ GV VY+
Sbjct: 62 EQHSGLKQSEAESCYINIARTLDFYGVELHSGRDLHNLDLMIGIASAGVAVYRKYICTSF 121
Query: 242 YFWPRITKVHFKETQFELRVLGK--DCNETSFFFEARSKTACKHLWKCSVEHHTFF---R 296
Y W I K+ FK +F + K + E F + +CK+LWK VEHHTFF +
Sbjct: 122 YPWVNILKISFKRKKFFIHQRQKQAESREHIVAFNMLNYRSCKNLWKSCVEHHTFFQAKK 181
Query: 297 MPENESNSL-------SRKLSKFGSIRYKHRYSGRTALQ--MSRDLSIQLPRPDQNVTRS 347
+ E N L SR K + +Y + G M R LS++
Sbjct: 182 LLPQEKNVLSQYWTMGSRNTKKSVNNQYCKKVIGGMVWNPAMRRSLSVE---------HL 232
Query: 348 RSKTYPKRIAQTQPAESNSISRIT------ANMENGENEGTIKIIAPSPVKSFKKAKNEN 401
+K+ P R P + R ++ +N NE T ++K +
Sbjct: 233 ETKSLPSRSPPITPNWRSPRLRHEIRKPRHSSADNLANEMTYITETEDVFYTYKGSLAPQ 292
Query: 402 SPDTQRSKSHAPWE----ENGPQSGLYNSPSDRTKSPKFPYTRRRNPSCGSDNDSVQPVR 457
D++ S++ +P + EN P S + SP +P G D +
Sbjct: 293 DSDSEVSQNRSPHQESLSENNPAQSYLTQKSSSSVSPSSNAPGSCSPD-GVDQQLLDDFH 351
Query: 458 RRKAHNSGEDS 468
R S ED+
Sbjct: 352 RVTKGGSTEDA 362
>gi|161702986 ezrin [Homo sapiens]
Length = 586
Score = 134 bits (338), Expect = 2e-31
Identities = 83/277 (29%), Positives = 140/277 (50%), Gaps = 15/277 (5%)
Query: 32 IKKSTKGSVVLDHVFHHVNLVEIDYFGLRYCDRSHQTYWLDPAKTLAEHKELINTGPPYT 91
I+ +T G + D V + L E+ YFGL Y D WL K ++ + + P
Sbjct: 20 IQPNTTGKQLFDQVVKTIGLREVWYFGLHYVDNKGFPTWLKLDKKVSAQE--VRKENPLQ 77
Query: 92 LYFGIKFYAEDPCK-LKEEITRYQFFLQVKQDVLQGRLPCPVNTAAQLGAYAIQSELGDY 150
F KFY ED + L ++IT+ FFLQVK+ +L + CP TA LG+YA+Q++ GDY
Sbjct: 78 FKFRAKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYCPPETAVLLGSYAVQAKFGDY 137
Query: 151 DPYKHTAGYVSEYRFVPDQ--------KEELEEAIERIHKTLMGQIPSEAELNYLRTAKS 202
+ H +GY+S R +P + +++ E+ I+ H G + A L YL+ A+
Sbjct: 138 NKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRIQVWHAEHRGMLKDNAMLEYLKIAQD 197
Query: 203 LEMYGVDLHPVYGENKSEYFLGLTPVGVVVY-KNKKQVGK--YFWPRITKVHFKETQFEL 259
LEMYG++ + + ++ +LG+ +G+ +Y K+ K K + W I + F + +F +
Sbjct: 198 LEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDDKLTPKIGFPWSEIRNISFNDKKFVI 257
Query: 260 RVLGKDCNETSFFFEARSKTACKHLWKCSVEHHTFFR 296
+ + K + F+ R + + L C H + R
Sbjct: 258 KPIDKKAPD-FVFYAPRLRINKRILQLCMGNHELYMR 293
>gi|21614499 ezrin [Homo sapiens]
Length = 586
Score = 134 bits (338), Expect = 2e-31
Identities = 83/277 (29%), Positives = 140/277 (50%), Gaps = 15/277 (5%)
Query: 32 IKKSTKGSVVLDHVFHHVNLVEIDYFGLRYCDRSHQTYWLDPAKTLAEHKELINTGPPYT 91
I+ +T G + D V + L E+ YFGL Y D WL K ++ + + P
Sbjct: 20 IQPNTTGKQLFDQVVKTIGLREVWYFGLHYVDNKGFPTWLKLDKKVSAQE--VRKENPLQ 77
Query: 92 LYFGIKFYAEDPCK-LKEEITRYQFFLQVKQDVLQGRLPCPVNTAAQLGAYAIQSELGDY 150
F KFY ED + L ++IT+ FFLQVK+ +L + CP TA LG+YA+Q++ GDY
Sbjct: 78 FKFRAKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYCPPETAVLLGSYAVQAKFGDY 137
Query: 151 DPYKHTAGYVSEYRFVPDQ--------KEELEEAIERIHKTLMGQIPSEAELNYLRTAKS 202
+ H +GY+S R +P + +++ E+ I+ H G + A L YL+ A+
Sbjct: 138 NKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRIQVWHAEHRGMLKDNAMLEYLKIAQD 197
Query: 203 LEMYGVDLHPVYGENKSEYFLGLTPVGVVVY-KNKKQVGK--YFWPRITKVHFKETQFEL 259
LEMYG++ + + ++ +LG+ +G+ +Y K+ K K + W I + F + +F +
Sbjct: 198 LEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDDKLTPKIGFPWSEIRNISFNDKKFVI 257
Query: 260 RVLGKDCNETSFFFEARSKTACKHLWKCSVEHHTFFR 296
+ + K + F+ R + + L C H + R
Sbjct: 258 KPIDKKAPD-FVFYAPRLRINKRILQLCMGNHELYMR 293
>gi|223941885 protein tyrosine phosphatase, non-receptor type 3
isoform 4 [Homo sapiens]
Length = 737
Score = 134 bits (337), Expect = 3e-31
Identities = 71/191 (37%), Positives = 105/191 (54%), Gaps = 5/191 (2%)
Query: 122 DVLQGRLPCPVNTAAQLGAYAIQSELGDYDPYKHTAGYVSEYRFVPDQKEELEEAIERIH 181
D+ +GRL CP+N+A L +YA+QS GDY+ H GY+S+ F+PDQ E+ +E +H
Sbjct: 2 DICEGRLTCPLNSAVVLASYAVQSHFGDYNSSIHHPGYLSDSHFIPDQNEDFLTKVESLH 61
Query: 182 KTLMGQIPSEAELNYLRTAKSLEMYGVDLHPVYGENKSEYFLGLTPVGVVVYKNKKQVGK 241
+ G SEAE Y+ A++L+ YGV+LH + + +G+ GV VY+
Sbjct: 62 EQHSGLKQSEAESCYINIARTLDFYGVELHSGRDLHNLDLMIGIASAGVAVYRKYICTSF 121
Query: 242 YFWPRITKVHFKETQFELRVLGK--DCNETSFFFEARSKTACKHLWKCSVEHHTFF---R 296
Y W I K+ FK +F + K + E F + +CK+LWK VEHHTFF +
Sbjct: 122 YPWVNILKISFKRKKFFIHQRQKQAESREHIVAFNMLNYRSCKNLWKSCVEHHTFFQAKK 181
Query: 297 MPENESNSLSR 307
+ E N LS+
Sbjct: 182 LLPQEKNVLSQ 192
>gi|4506467 radixin [Homo sapiens]
Length = 583
Score = 132 bits (332), Expect = 1e-30
Identities = 81/277 (29%), Positives = 141/277 (50%), Gaps = 15/277 (5%)
Query: 32 IKKSTKGSVVLDHVFHHVNLVEIDYFGLRYCDRSHQTYWLDPAKTLAEHKELINTGPPYT 91
I+ +T G + D V V L E+ +FGL+Y D + WL K + + + P
Sbjct: 20 IQPNTTGKQLFDQVVKTVGLREVWFFGLQYVDSKGYSTWLKLNKKVTQQD--VKKENPLQ 77
Query: 92 LYFGIKFYAEDPCK-LKEEITRYQFFLQVKQDVLQGRLPCPVNTAAQLGAYAIQSELGDY 150
F KF+ ED + L +EIT+ FFLQVK+ +L + CP TA L +YA+Q++ GDY
Sbjct: 78 FKFRAKFFPEDVSEELIQEITQRLFFLQVKEAILNDEIYCPPETAVLLASYAVQAKYGDY 137
Query: 151 DPYKHTAGYVSEYRFVPDQ--------KEELEEAIERIHKTLMGQIPSEAELNYLRTAKS 202
+ H GY++ R +P + KE+ EE I+ H+ G + ++ + YL+ A+
Sbjct: 138 NKEIHKPGYLANDRLLPQRVLEQHKLTKEQWEERIQNWHEEHRGMLREDSMMEYLKIAQD 197
Query: 203 LEMYGVDLHPVYGENKSEYFLGLTPVGVVVYKNKKQVGK---YFWPRITKVHFKETQFEL 259
LEMYGV+ + + +E +LG+ +G+ +Y++ ++ + W I + F + +F +
Sbjct: 198 LEMYGVNYFEIKNKKGTELWLGVDALGLNIYEHDDKLTPKIGFPWSEIRNISFNDKKFVI 257
Query: 260 RVLGKDCNETSFFFEARSKTACKHLWKCSVEHHTFFR 296
+ + K + F+ R + + L C H + R
Sbjct: 258 KPIDKKAPD-FVFYAPRLRINKRILALCMGNHELYMR 293
>gi|4505257 moesin [Homo sapiens]
Length = 577
Score = 129 bits (324), Expect = 9e-30
Identities = 81/277 (29%), Positives = 140/277 (50%), Gaps = 15/277 (5%)
Query: 32 IKKSTKGSVVLDHVFHHVNLVEIDYFGLRYCDRSHQTYWLDPAKTLAEHKELINTGPPYT 91
I+ +T G + D V + L E+ +FGL+Y D + WL K + + P
Sbjct: 20 IQPNTTGKQLFDQVVKTIGLREVWFFGLQYQDTKGFSTWLKLNKKVTAQD--VRKESPLL 77
Query: 92 LYFGIKFYAEDPCK-LKEEITRYQFFLQVKQDVLQGRLPCPVNTAAQLGAYAIQSELGDY 150
F KFY ED + L ++IT+ FFLQVK+ +L + CP TA L +YA+QS+ GD+
Sbjct: 78 FKFRAKFYPEDVSEELIQDITQRLFFLQVKEGILNDDIYCPPETAVLLASYAVQSKYGDF 137
Query: 151 DPYKHTAGYVSEYRFVPDQ--------KEELEEAIERIHKTLMGQIPSEAELNYLRTAKS 202
+ H +GY++ + +P + K++ EE I+ H+ G + +A L YL+ A+
Sbjct: 138 NKEVHKSGYLAGDKLLPQRVLEQHKLNKDQWEERIQVWHEEHRGMLREDAVLEYLKIAQD 197
Query: 203 LEMYGVDLHPVYGENKSEYFLGLTPVGVVVYKNKKQVGK---YFWPRITKVHFKETQFEL 259
LEMYGV+ + + SE +LG+ +G+ +Y+ ++ + W I + F + +F +
Sbjct: 198 LEMYGVNYFSIKNKKGSELWLGVDALGLNIYEQNDRLTPKIGFPWSEIRNISFNDKKFVI 257
Query: 260 RVLGKDCNETSFFFEARSKTACKHLWKCSVEHHTFFR 296
+ + K + F+ R + + L C H + R
Sbjct: 258 KPIDKKAPD-FVFYAPRLRINKRILALCMGNHELYMR 293
>gi|34328899 protein tyrosine phosphatase, non-receptor type 14
[Homo sapiens]
Length = 1187
Score = 128 bits (321), Expect = 2e-29
Identities = 87/306 (28%), Positives = 156/306 (50%), Gaps = 24/306 (7%)
Query: 11 FYCEVLLLDESKLTLTTQQQGIKKSTKGSVVLDHVFHHVNLVEIDYFGLRYCDRSHQTYW 70
F + LLD + + T + + G L+ V + L E YFGL + +S Q W
Sbjct: 21 FVTRIRLLDSNVIECT-----LSVESTGQECLEAVAQRLELRETHYFGLWFLSKSQQARW 75
Query: 71 LDPAKTLAEHKELINTGPPYTLYFGIKFYAEDPCKLKEEITRYQFFLQVKQDVLQGRLPC 130
++ K L +H + P L+FG+ FY + L++E TRYQ++LQVK+DVL+GRL C
Sbjct: 76 VELEKPLKKHLDKFANEP--LLFFGVMFYVPNVSWLQQEATRYQYYLQVKKDVLEGRLRC 133
Query: 131 PVNTAAQLGAYAIQSELGDYDPYKHTAGYVSEYRFVPDQ-------KEELEEAIERIHKT 183
++ +L A+Q++ GDY+ + + ++ EY P EEL + + + HK
Sbjct: 134 TLDQVIRLAGLAVQADFGDYNQF-DSQDFLREYVLFPMDLALEEAVLEELTQKVAQEHKA 192
Query: 184 LMGQIPSEAELNYLRTAKSLEMYGVDLHPVYGENKSEYFLGLTPVGVVVYKNK--KQVGK 241
G +P+EAEL Y+ + L+ +G ++ PV + + LG+ +G+ V +N+ +Q
Sbjct: 193 HSGILPAEAELMYINEVERLDGFGQEIFPVKDNHGNCVHLGIFFMGIFV-RNRIGRQAVI 251
Query: 242 YFWPRITKVHFKETQFELRVLGKDCNETSFFFEARSKTACKHLWKCSVEHHTFFRMPE-- 299
Y W + + ++ + ++ K+ ET+ F + A K++ + H F++ +
Sbjct: 252 YRWNDMGNITHNKSTILVELINKE--ETALFHTDDIENA-KYISRLFATRHKFYKQNKIC 308
Query: 300 -NESNS 304
+SNS
Sbjct: 309 TEQSNS 314
>gi|32967254 neurofibromin 2 isoform 2 [Homo sapiens]
Length = 590
Score = 122 bits (307), Expect = 8e-28
Identities = 99/388 (25%), Positives = 179/388 (46%), Gaps = 25/388 (6%)
Query: 37 KGSVVLDHVFHHVNLVEIDYFGLRYCDRSHQTYWLDPAKTLAEHKELINTGPPYTLYFGI 96
KG + D V + L E +FGL+Y + WL K + +H ++ P T +F
Sbjct: 42 KGKDLFDLVCRTLGLRETWFFGLQYTIKD-TVAWLKMDKKVLDHD--VSKEEPVTFHFLA 98
Query: 97 KFYAEDPCK-LKEEITRYQFFLQVKQDVLQGRLPCPVNTAAQLGAYAIQSELGDYDPYKH 155
KFY E+ + L +EIT++ FFLQVK+ +L ++ CP + L +YA+Q++ GDYDP H
Sbjct: 99 KFYPENAEEELVQEITQHLFFLQVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVH 158
Query: 156 TAGYVSEYRFVPDQ--------KEELEEAIERIHKTLMGQIPSEAELNYLRTAKSLEMYG 207
G++++ +P + E EE I + G+ EAE+ YL+ A+ LEMYG
Sbjct: 159 KRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYG 218
Query: 208 VDLHPVYGENKSEYFLGLTPVGVVVYKNKKQVG---KYFWPRITKVHFKETQFELRVLGK 264
V+ + + +E LG+ +G+ +Y + ++ + W I + + + +F ++ L K
Sbjct: 219 VNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDK 278
Query: 265 DCNETSFFFEARSKTACKHLWKCSVEHHTFFRMPENESNSLSRKLSKFGSIRYKHRYSGR 324
+ F F + K + + + +H F M +++SL + K + K R
Sbjct: 279 KID--VFKFNSSKLRVNKLILQLCIGNHDLF-MRRRKADSLEVQQMKAQAREEKAR---- 331
Query: 325 TALQMSRDLSIQLPRPDQNVTRSRSKTYPKRIAQTQPAESNSISRITANMENGENEGTIK 384
QM R + + + R+R + +R+ Q + + + + + E +
Sbjct: 332 --KQMERQRLAREKQMREEAERTRDE-LERRLLQMKEEATMANEALMRSEETADLLAEKA 388
Query: 385 IIAPSPVKSFKKAKNENSPDTQRSKSHA 412
I K + E + QR K+ A
Sbjct: 389 QITEEEAKLLAQKAAEAEQEMQRIKATA 416
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.129 0.378
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,473,856
Number of Sequences: 37866
Number of extensions: 1312014
Number of successful extensions: 5947
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 135
Number of HSP's successfully gapped in prelim test: 302
Number of HSP's that attempted gapping in prelim test: 4253
Number of HSP's gapped (non-prelim): 1106
length of query: 686
length of database: 18,247,518
effective HSP length: 109
effective length of query: 577
effective length of database: 14,120,124
effective search space: 8147311548
effective search space used: 8147311548
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.