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Search of human proteins with 85815829
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|85815829 SH3-domain binding protein 1 [Homo sapiens]
(701 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|85815829 SH3-domain binding protein 1 [Homo sapiens] 1382 0.0
gi|54860105 nadrin isoform 2 [Homo sapiens] 503 e-142
gi|54860079 nadrin isoform 1 [Homo sapiens] 485 e-137
gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens] 464 e-130
gi|23510413 sorting nexin 26 [Homo sapiens] 121 2e-27
gi|156071465 Rho GTPase activating protein 4 [Homo sapiens] 112 2e-24
gi|4502813 chimerin (chimaerin) 1 isoform a [Homo sapiens] 109 8e-24
gi|209364623 chimerin (chimaerin) 1 isoform b [Homo sapiens] 109 8e-24
gi|229094128 active breakpoint cluster region-related protein i... 108 2e-23
gi|38679957 active breakpoint cluster region-related protein is... 108 2e-23
gi|38679954 active breakpoint cluster region-related protein is... 108 2e-23
gi|34013590 Rho GTPase activating protein 2 [Homo sapiens] 106 6e-23
gi|111154090 Rho GTPase activating protein 24 isoform 3 [Homo sa... 106 8e-23
gi|111154099 Rho GTPase activating protein 24 isoform 2 [Homo sa... 106 8e-23
gi|111154092 Rho GTPase activating protein 24 isoform 1 [Homo sa... 106 8e-23
gi|21314774 T-cell activation Rho GTPase-activating protein isof... 105 1e-22
gi|186928844 Cdc42 GTPase-activating protein [Homo sapiens] 105 1e-22
gi|218083800 Rho GTPase-activating protein isoform 1 [Homo sapiens] 103 4e-22
gi|29469071 Rho GTPase-activating protein isoform 2 [Homo sapiens] 103 4e-22
gi|82546845 breakpoint cluster region isoform 2 [Homo sapiens] 102 9e-22
gi|82546843 breakpoint cluster region isoform 1 [Homo sapiens] 102 9e-22
gi|4757980 beta chimerin isoform 2 [Homo sapiens] 102 2e-21
gi|91106928 beta chimerin isoform 1 [Homo sapiens] 102 2e-21
gi|4757766 Rho GTPase activating protein 1 [Homo sapiens] 101 2e-21
gi|71040096 Rho GTPase activating protein 30 isoform 2 [Homo sap... 101 2e-21
gi|71040098 Rho GTPase activating protein 30 isoform 1 [Homo sap... 101 2e-21
gi|26986534 Rho GTPase activating protein 12 [Homo sapiens] 100 8e-21
gi|194272142 myosin IXB isoform 2 [Homo sapiens] 99 2e-20
gi|33356170 myosin IXB isoform 1 [Homo sapiens] 99 2e-20
gi|50843948 Rho GTPase activating protein 10 [Homo sapiens] 98 2e-20
>gi|85815829 SH3-domain binding protein 1 [Homo sapiens]
Length = 701
Score = 1382 bits (3576), Expect = 0.0
Identities = 701/701 (100%), Positives = 701/701 (100%)
Query: 1 MMKRQLHRMRQLAQTGSLGRTPETAEFLGEDLLQVEQRLEPAKRAAHNIHKRLQACLQGQ 60
MMKRQLHRMRQLAQTGSLGRTPETAEFLGEDLLQVEQRLEPAKRAAHNIHKRLQACLQGQ
Sbjct: 1 MMKRQLHRMRQLAQTGSLGRTPETAEFLGEDLLQVEQRLEPAKRAAHNIHKRLQACLQGQ 60
Query: 61 SGADMDKRVKKLPLMALSTTMAESFKELDPDSSMGKALEMSCAIQNQLARILAEFEMTLE 120
SGADMDKRVKKLPLMALSTTMAESFKELDPDSSMGKALEMSCAIQNQLARILAEFEMTLE
Sbjct: 61 SGADMDKRVKKLPLMALSTTMAESFKELDPDSSMGKALEMSCAIQNQLARILAEFEMTLE 120
Query: 121 RDVLQPLSRLSEEELPAILKHKKSLQKLVSDWNTLKSRLSQATKNSGSSQGLGGSPGSHS 180
RDVLQPLSRLSEEELPAILKHKKSLQKLVSDWNTLKSRLSQATKNSGSSQGLGGSPGSHS
Sbjct: 121 RDVLQPLSRLSEEELPAILKHKKSLQKLVSDWNTLKSRLSQATKNSGSSQGLGGSPGSHS 180
Query: 181 HTTMANKVETLKEEEEELKRKVEQCRDEYLADLYHFVTKEDSYANYFIRLLEIQADYHRR 240
HTTMANKVETLKEEEEELKRKVEQCRDEYLADLYHFVTKEDSYANYFIRLLEIQADYHRR
Sbjct: 181 HTTMANKVETLKEEEEELKRKVEQCRDEYLADLYHFVTKEDSYANYFIRLLEIQADYHRR 240
Query: 241 SLSSLDTALAELRENHGQADHSPSMTATHFPRVYGVSLATHLQELGREIALPIEACVMML 300
SLSSLDTALAELRENHGQADHSPSMTATHFPRVYGVSLATHLQELGREIALPIEACVMML
Sbjct: 241 SLSSLDTALAELRENHGQADHSPSMTATHFPRVYGVSLATHLQELGREIALPIEACVMML 300
Query: 301 LSEGMKEEGLFRLAAGASVLKRLKQTMASDPHSLEEFCSDPHAVAGALKSYLRELPEPLM 360
LSEGMKEEGLFRLAAGASVLKRLKQTMASDPHSLEEFCSDPHAVAGALKSYLRELPEPLM
Sbjct: 301 LSEGMKEEGLFRLAAGASVLKRLKQTMASDPHSLEEFCSDPHAVAGALKSYLRELPEPLM 360
Query: 361 TFDLYDDWMRAASLKEPGARLQALQEVCSRLPPENLSNLRYLMKFLARLAEEQEVNKMTP 420
TFDLYDDWMRAASLKEPGARLQALQEVCSRLPPENLSNLRYLMKFLARLAEEQEVNKMTP
Sbjct: 361 TFDLYDDWMRAASLKEPGARLQALQEVCSRLPPENLSNLRYLMKFLARLAEEQEVNKMTP 420
Query: 421 SNIAIVLGPNLLWPPEKEGDQAQLDAASVSSIQVVGVVEALIQSADTLFPGDINFNVSGL 480
SNIAIVLGPNLLWPPEKEGDQAQLDAASVSSIQVVGVVEALIQSADTLFPGDINFNVSGL
Sbjct: 421 SNIAIVLGPNLLWPPEKEGDQAQLDAASVSSIQVVGVVEALIQSADTLFPGDINFNVSGL 480
Query: 481 FSAVTLQDTVSDRLASEELPSTAVPTPATTPAPAPAPAPAPAPALASAATKERTESEVPP 540
FSAVTLQDTVSDRLASEELPSTAVPTPATTPAPAPAPAPAPAPALASAATKERTESEVPP
Sbjct: 481 FSAVTLQDTVSDRLASEELPSTAVPTPATTPAPAPAPAPAPAPALASAATKERTESEVPP 540
Query: 541 RPASPKVTRSPPETAAPVEDMARRTKRPAPARPTMPPPQVSGSRSSPPAPPLPPGSGSPG 600
RPASPKVTRSPPETAAPVEDMARRTKRPAPARPTMPPPQVSGSRSSPPAPPLPPGSGSPG
Sbjct: 541 RPASPKVTRSPPETAAPVEDMARRTKRPAPARPTMPPPQVSGSRSSPPAPPLPPGSGSPG 600
Query: 601 TPQALPRRLVGSSLRAPTVPPPLPPTPPQPARRQSRRSPASPSPASPGPASPSPVSLSNP 660
TPQALPRRLVGSSLRAPTVPPPLPPTPPQPARRQSRRSPASPSPASPGPASPSPVSLSNP
Sbjct: 601 TPQALPRRLVGSSLRAPTVPPPLPPTPPQPARRQSRRSPASPSPASPGPASPSPVSLSNP 660
Query: 661 AQVDLGAATAEGGAPEAISGVPTPPAIPPQPRPRSLASETN 701
AQVDLGAATAEGGAPEAISGVPTPPAIPPQPRPRSLASETN
Sbjct: 661 AQVDLGAATAEGGAPEAISGVPTPPAIPPQPRPRSLASETN 701
>gi|54860105 nadrin isoform 2 [Homo sapiens]
Length = 803
Score = 503 bits (1294), Expect = e-142
Identities = 318/774 (41%), Positives = 435/774 (56%), Gaps = 109/774 (14%)
Query: 2 MKRQLHRMRQLAQTGSLGRTPETAEFLGEDLLQVEQRLEPAKRAAHNIHKRLQACLQGQS 61
MK+Q +RM+QLA ++GR +T E L EDLLQ+E+RL+ + H+ HKRL AC QGQ
Sbjct: 1 MKKQFNRMKQLANQ-TVGRAEKT-EVLSEDLLQIERRLDTVRSICHHSHKRLVACFQGQH 58
Query: 62 GADMDKRVKKLPLMALSTTMAESFKELDPDSSMGKALEMSCAIQNQLARILAEFEMTLER 121
G D ++R KKLPL AL+ M E+ +L+ DS +GK LE +NQLA L++ E+ +E+
Sbjct: 59 GTDAERRHKKLPLTALAQNMQEASTQLE-DSLLGKMLETCGDAENQLALELSQHEVFVEK 117
Query: 122 DVLQPLSRLSEEELPAILKHKKSLQKLVSDWNTLKSRLSQATKNSGSS-QGLGGSPGSHS 180
+++ PL ++E E+P I K +K L +LV DW+++++R +QA K+SG++ QGL
Sbjct: 118 EIVDPLYGIAEVEIPNIQKQRKQLARLVLDWDSVRARWNQAHKSSGTNFQGL-------- 169
Query: 181 HTTMANKVETLKEEEEELKRKVEQCRDEYLADLYHFVTKEDSYANYFIRLLEIQADYHRR 240
+K++TLKEE +E KVEQC+D+ AD+Y+F+ KE Y +F+ LLE QADYHR+
Sbjct: 170 ----PSKIDTLKEEMDEAGNKVEQCKDQLAADMYNFMAKEGEYGKFFVTLLEAQADYHRK 225
Query: 241 SLSSLDTALAELRENHGQADHSPSMTATHFPRVYGVSLATHLQELGREIALPIEACVMML 300
+L+ L+ L E+R + + P+ +G L HL+ GREIALPIEACVM+L
Sbjct: 226 ALAVLEKTLPEMRAHQDKWAEKPA---------FGTPLEEHLKRSGREIALPIEACVMLL 276
Query: 301 LSEGMKEEGLFRLAAGASVLKRLKQTMASDPHSLEEFCSDPHAVAGALKSYLRELPEPLM 360
L GMKEEGLFR+ AGAS LK+LK + L+EF SDPHAVAGALKSYLRELPEPLM
Sbjct: 277 LETGMKEEGLFRIGAGASKLKKLKAALDCSTSHLDEFYSDPHAVAGALKSYLRELPEPLM 336
Query: 361 TFDLYDDWMRAASLKEPGARLQALQEVCSRLPPENLSNLRYLMKFLARLAEEQEVNKMTP 420
TF+LY++W + AS+++ +LQ L C +LPP+N N RYL+KFLA+LA+ +VNKMTP
Sbjct: 337 TFNLYEEWTQVASVQDQDKKLQDLWRTCQKLPPQNFVNFRYLIKFLAKLAQTSDVNKMTP 396
Query: 421 SNIAIVLGPNLLWPPEKEGDQAQLDAASVSSIQVVGVVEALIQSADTLFPGDINFNVSGL 480
SNIAIVLGPNLLW EG A++ AA +S+ VV V+E +IQ AD FP ++ FNVS
Sbjct: 397 SNIAIVLGPNLLW-ARNEGTLAEMAAA--TSVHVVAVIEPIIQHADWFFPEEVEFNVSEA 453
Query: 481 FSAVTL----------QDTVSDRLASEELPSTAV--------PTPATTPAPAPAPAPAPA 522
F +T D+ S L + S AV +P P A PAP
Sbjct: 454 FVPLTTPSSNHSFHTGNDSDSGTLERKRPASMAVMEGDLVKKESPPKPKDPVSAAVPAPG 513
Query: 523 PALASAATKERTESEVPPRPASPKVTRSPPETAA--PVEDMARRTKRPAPA--RPTMPPP 578
+ A+ +++ S +++ P AA + R K+PAPA +P PPP
Sbjct: 514 RNNSQIAS---GQNQPQAAAGSHQLSMGQPHNAAGPSPHTLRRAVKKPAPAPPKPGNPPP 570
Query: 579 QVSGSRSS-----------------PPAPPL-----PPGSGSPGTPQALPRRLVG--SSL 614
G +SS P+PP PPG S + + PRR S +
Sbjct: 571 GHPGGQSSSGTSQHPPSLSPKPPTRSPSPPTQHTGQPPGQPSAPSQLSAPRRYSSSLSPI 630
Query: 615 RAPTVPPPLPPT--------------PPQPARRQSRRSPASPS---PASPGPASPSPVSL 657
+AP PPP PPT PP P S PS P +P P S P+
Sbjct: 631 QAPNHPPPQPPTQATPLMHTKPNSQGPPNPMALPSEHGLEQPSHTPPQTPTPPSTPPLGK 690
Query: 658 SNPAQVDLGAATAEGGAPEAIS----------GVPTP---PAIPPQPRPRSLAS 698
NP+ T GG PE VP P P++PP P+P + S
Sbjct: 691 QNPSLP--APQTLAGGNPETAQPHAGTLPRPRPVPKPRNRPSVPPPPQPPGVHS 742
Score = 50.4 bits (119), Expect = 5e-06
Identities = 55/224 (24%), Positives = 71/224 (31%), Gaps = 56/224 (25%)
Query: 491 SDRLASEELPSTAVPTPATT------PAPAPAPAPAPAPALASAATKERTESEVPP-RPA 543
S +L+ + + A P+P T PAPAP P P + T P P
Sbjct: 532 SHQLSMGQPHNAAGPSPHTLRRAVKKPAPAPPKPGNPPPGHPGGQSSSGTSQHPPSLSPK 591
Query: 544 SPKVTRSPP--ETAAPVEDMARRTKRPAPARPTMPPPQVSGSRSSPPAPPLP-------- 593
P + SPP T P + ++ AP R + + PP PP
Sbjct: 592 PPTRSPSPPTQHTGQPPGQPSAPSQLSAPRRYSSSLSPIQAPNHPPPQPPTQATPLMHTK 651
Query: 594 PGSGSPGTPQALPRRLVGSSLRAPTVPPPLPPTPP------------------------- 628
P S P P ALP L P+ PP PTPP
Sbjct: 652 PNSQGPPNPMALPSE---HGLEQPSHTPPQTPTPPSTPPLGKQNPSLPAPQTLAGGNPET 708
Query: 629 -----------QPARRQSRRSPASPSPASPGPASPSPVSLSNPA 661
+P + R P P PG S SL+N A
Sbjct: 709 AQPHAGTLPRPRPVPKPRNRPSVPPPPQPPGVHSAGDSSLTNTA 752
Score = 35.8 bits (81), Expect = 0.14
Identities = 28/117 (23%), Positives = 39/117 (33%), Gaps = 14/117 (11%)
Query: 500 PSTAVPTPATTPAPAPAPAPAPAPALASAATKERTESEVPPRPASPKVTRSPPETAAP-- 557
P+ A P T P P P P+ T + P P++P + + P AP
Sbjct: 641 PTQATPLMHTKPNSQGPPNPMALPSEHGLEQPSHTPPQTPTPPSTPPLGKQNPSLPAPQT 700
Query: 558 --------VEDMARRTKRPAPARPTMPPPQVSGSRSSPPAPPLPPGSGSPGTPQALP 606
+ A RP P +P P+ S PP PP +G P
Sbjct: 701 LAGGNPETAQPHAGTLPRPRP----VPKPRNRPSVPPPPQPPGVHSAGDSSLTNTAP 753
Score = 31.6 bits (70), Expect = 2.6
Identities = 23/77 (29%), Positives = 26/77 (33%), Gaps = 21/77 (27%)
Query: 500 PSTAVPTPATTPAPAPAPAPAPAPALASAATKERTESEVPPRPASPKV--------TRSP 551
P TA P T P P P P P P+ VPP P P V T +
Sbjct: 706 PETAQPHAGTLPRPRPVPKPRNRPS-------------VPPPPQPPGVHSAGDSSLTNTA 752
Query: 552 PETAAPVEDMARRTKRP 568
P + V D R P
Sbjct: 753 PTASKIVTDSNSRVSEP 769
>gi|54860079 nadrin isoform 1 [Homo sapiens]
Length = 881
Score = 485 bits (1249), Expect = e-137
Identities = 328/849 (38%), Positives = 443/849 (52%), Gaps = 181/849 (21%)
Query: 2 MKRQLHRMRQLAQTGSLGRTPETAEFLGEDLLQVEQRLEPAKRAAHNIHKRLQACLQGQS 61
MK+Q +RM+QLA ++GR +T E L EDLLQ+E+RL+ + H+ HKRL AC QGQ
Sbjct: 1 MKKQFNRMKQLANQ-TVGRAEKT-EVLSEDLLQIERRLDTVRSICHHSHKRLVACFQGQH 58
Query: 62 GADMDKRVKKLPLMALSTTMAESFKELDPDSSMGKALEMSCAIQNQLARILAEFEMTLER 121
G D ++R KKLPL AL+ M E+ +L+ DS +GK LE +NQLA L++ E+ +E+
Sbjct: 59 GTDAERRHKKLPLTALAQNMQEASTQLE-DSLLGKMLETCGDAENQLALELSQHEVFVEK 117
Query: 122 DVLQPLSRLSEEELPAILKHKKSLQKLVSDWNTLKSRLSQATKNSGSS-QGLGGSPGSHS 180
+++ PL ++E E+P I K +K L +LV DW+++++R +QA K+SG++ QGL
Sbjct: 118 EIVDPLYGIAEVEIPNIQKQRKQLARLVLDWDSVRARWNQAHKSSGTNFQGL-------- 169
Query: 181 HTTMANKVETLKEEEEELKRKVEQCRDEYLADLYHFVTKEDSYANYFIRLLEIQADYHRR 240
+K++TLKEE +E KVEQC+D+ AD+Y+F+ KE Y +F+ LLE QADYHR+
Sbjct: 170 ----PSKIDTLKEEMDEAGNKVEQCKDQLAADMYNFMAKEGEYGKFFVTLLEAQADYHRK 225
Query: 241 SLSSLDTALAELRENHGQADHSPSMTATHFPRVYGVSLATHLQELGREIALPIEACVMML 300
+L+ L+ L E+R + + P+ +G L HL+ GREIALPIEACVM+L
Sbjct: 226 ALAVLEKTLPEMRAHQDKWAEKPA---------FGTPLEEHLKRSGREIALPIEACVMLL 276
Query: 301 LSEGMKEEGLFRLAAGASVLKRLKQTMASDPHSLEEFCSDPHAVAGALKSYLRELPEPLM 360
L GMKEEGLFR+ AGAS LK+LK + L+EF SDPHAVAGALKSYLRELPEPLM
Sbjct: 277 LETGMKEEGLFRIGAGASKLKKLKAALDCSTSHLDEFYSDPHAVAGALKSYLRELPEPLM 336
Query: 361 TFDLYDDWMRAASLKEPGARLQALQEVCSRLPPENLSNLRYLMKFLARLAEEQEVNKMTP 420
TF+LY++W + AS+++ +LQ L C +LPP+N N RYL+KFLA+LA+ +VNKMTP
Sbjct: 337 TFNLYEEWTQVASVQDQDKKLQDLWRTCQKLPPQNFVNFRYLIKFLAKLAQTSDVNKMTP 396
Query: 421 SNIAIVLGPNLLWPPEKEGDQAQLDAASVSSIQVVGVVEALIQSADTLFPGDINFNVSGL 480
SNIAIVLGPNLLW EG A++ AA +S+ VV V+E +IQ AD FP ++ FNVS
Sbjct: 397 SNIAIVLGPNLLW-ARNEGTLAEMAAA--TSVHVVAVIEPIIQHADWFFPEEVEFNVSEA 453
Query: 481 FSAVTL----------QDTVSDRLASEELPSTAV-------------------------- 504
F +T D+ S L + S AV
Sbjct: 454 FVPLTTPSSNHSFHTGNDSDSGTLERKRPASMAVMEGDLVKKESFGVKLMDFQAHRRGGT 513
Query: 505 ---------------PTPATTPAPA-PAPAPAPAPA---------LASAATKERTESE-- 537
PT +T PA P P P + A +SA E+ S
Sbjct: 514 LNRKHISPAFQPPLPPTDGSTVVPAGPEPPPQSSRAESSSGGGTVPSSAGILEQGPSPGD 573
Query: 538 -VPPRPASPKVTRSP---------------PETAAPVEDMA----------------RRT 565
PP+P P P P+ AA ++ R
Sbjct: 574 GSPPKPKDPVSAAVPAPGRNNSQIASGQNQPQAAAGSHQLSMGQPHNAAGPSPHTLRRAV 633
Query: 566 KRPAPA--RPTMPPPQVSGSRSS-----------------PPAPPL-----PPGSGSPGT 601
K+PAPA +P PPP G +SS P+PP PPG S +
Sbjct: 634 KKPAPAPPKPGNPPPGHPGGQSSSGTSQHPPSLSPKPPTRSPSPPTQHTGQPPGQPSAPS 693
Query: 602 PQALPRRLVG--SSLRAPTVPPPLPPT--------------PPQPARRQSRRSPASPS-- 643
+ PRR S ++AP PPP PPT PP P S PS
Sbjct: 694 QLSAPRRYSSSLSPIQAPNHPPPQPPTQATPLMHTKPNSQGPPNPMALPSEHGLEQPSHT 753
Query: 644 -PASPGPASPSPVSLSNPAQVDLGAATAEGGAPEAIS----------GVPTP---PAIPP 689
P +P P S P+ NP+ T GG PE VP P P++PP
Sbjct: 754 PPQTPTPPSTPPLGKQNPSLP--APQTLAGGNPETAQPHAGTLPRPRPVPKPRNRPSVPP 811
Query: 690 QPRPRSLAS 698
P+P + S
Sbjct: 812 PPQPPGVHS 820
Score = 50.4 bits (119), Expect = 5e-06
Identities = 55/224 (24%), Positives = 71/224 (31%), Gaps = 56/224 (25%)
Query: 491 SDRLASEELPSTAVPTPATT------PAPAPAPAPAPAPALASAATKERTESEVPP-RPA 543
S +L+ + + A P+P T PAPAP P P + T P P
Sbjct: 610 SHQLSMGQPHNAAGPSPHTLRRAVKKPAPAPPKPGNPPPGHPGGQSSSGTSQHPPSLSPK 669
Query: 544 SPKVTRSPP--ETAAPVEDMARRTKRPAPARPTMPPPQVSGSRSSPPAPPLP-------- 593
P + SPP T P + ++ AP R + + PP PP
Sbjct: 670 PPTRSPSPPTQHTGQPPGQPSAPSQLSAPRRYSSSLSPIQAPNHPPPQPPTQATPLMHTK 729
Query: 594 PGSGSPGTPQALPRRLVGSSLRAPTVPPPLPPTPP------------------------- 628
P S P P ALP L P+ PP PTPP
Sbjct: 730 PNSQGPPNPMALPSE---HGLEQPSHTPPQTPTPPSTPPLGKQNPSLPAPQTLAGGNPET 786
Query: 629 -----------QPARRQSRRSPASPSPASPGPASPSPVSLSNPA 661
+P + R P P PG S SL+N A
Sbjct: 787 AQPHAGTLPRPRPVPKPRNRPSVPPPPQPPGVHSAGDSSLTNTA 830
Score = 31.6 bits (70), Expect = 2.6
Identities = 23/77 (29%), Positives = 26/77 (33%), Gaps = 21/77 (27%)
Query: 500 PSTAVPTPATTPAPAPAPAPAPAPALASAATKERTESEVPPRPASPKV--------TRSP 551
P TA P T P P P P P P+ VPP P P V T +
Sbjct: 784 PETAQPHAGTLPRPRPVPKPRNRPS-------------VPPPPQPPGVHSAGDSSLTNTA 830
Query: 552 PETAAPVEDMARRTKRP 568
P + V D R P
Sbjct: 831 PTASKIVTDSNSRVSEP 847
>gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens]
Length = 818
Score = 464 bits (1193), Expect = e-130
Identities = 295/737 (40%), Positives = 413/737 (56%), Gaps = 75/737 (10%)
Query: 2 MKRQLHRMRQLAQTGSLGRTPETAEFLGEDLLQVEQRLEPAKRAAHNIHKRLQACLQGQS 61
MK+Q +RMRQLA ++GR +T E L EDLLQVE+RLE K+ +H+ HK+L ACLQGQ
Sbjct: 1 MKKQFNRMRQLANQ-TVGRAEKT-EVLSEDLLQVEKRLELVKQVSHSTHKKLTACLQGQQ 58
Query: 62 GADMDKRVKKLPLMALSTTMAESFKELDPDSSMGKALEMSCAIQNQLARILAEFEMTLER 121
GA+ DKR KKLPL L+ + E L D+ +GK L++ +++LA+ L FE+ +ER
Sbjct: 59 GAEADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEDKLAQELIHFELQVER 118
Query: 122 DVLQPLSRLSEEELPAILKHKKSLQKLVSDWNTLKSRLSQATKNSGSSQGLGGSPGSHSH 181
DV++PL L+E E+P I K +K L KLV D ++ ++R Q +K+SG S L +
Sbjct: 119 DVIEPLFLLAEVEIPNIQKQRKHLAKLVLDMDSSRTRWQQTSKSSGLSSSLQPAGA---- 174
Query: 182 TTMANKVETLKEEEEELKRKVEQCRDEYLADLYHFVTKEDSYANYFIRLLEIQADYHRRS 241
K + L+EE EE +VE CRD+ AD+Y FV KE YANYF L+E+QA+YHR+S
Sbjct: 175 -----KADALREEMEEAANRVEICRDQLSADMYSFVAKEIDYANYFQTLIEVQAEYHRKS 229
Query: 242 LSSLDTALAELRENHGQADHSPSMTATHFPRVYGVSLATHLQELGREIALPIEACVMMLL 301
L+ L L +++ PS +G L HL GREIA PIEACV MLL
Sbjct: 230 LTLLQAVLPQIKAQQEAWVEKPS---------FGKPLEEHLTISGREIAFPIEACVTMLL 280
Query: 302 SEGMKEEGLFRLAAGASVLKRLKQTMASDPHSLEEFCSDPHAVAGALKSYLRELPEPLMT 361
GM+EEGLFR+A AS LK+LK + ++E+ +DPHA+AGALKSYLRELPEPLMT
Sbjct: 281 ECGMQEEGLFRVAPSASKLKKLKAALDCCVVDVQEYSADPHAIAGALKSYLRELPEPLMT 340
Query: 362 FDLYDDWMRAASLKEPGARLQALQEVCSRLPPENLSNLRYLMKFLARLAEEQEVNKMTPS 421
F+LYD+W++A++++E +LQAL C +LP N +N+RYL+KFL++L+E Q+VNKMTPS
Sbjct: 341 FELYDEWIQASNVQEQDKKLQALWNACEKLPKANHNNIRYLIKFLSKLSEYQDVNKMTPS 400
Query: 422 NIAIVLGPNLLWPPEKEGDQAQLDAASVSSIQVVGVVEALIQSADTLFPGDINFNVSGLF 481
N+AIVLGPNLLW P+ EG+ ++ + S+Q+VG++E +IQ AD FPG+I FN++G +
Sbjct: 401 NMAIVLGPNLLW-PQAEGNITEM--MTTVSLQIVGIIEPIIQHADWFFPGEIEFNITGNY 457
Query: 482 SAVTLQDTVSDRLASEELPSTAVPTPATTPAPAPAPAPAPAP------------------ 523
S + +++P+P PA P A P
Sbjct: 458 G--------SPVHVNHNANYSSMPSPDMDPADRRQPEQARRPLSVATDNMMLEFYKKDGL 509
Query: 524 -ALASAATKERTESEVPPRPASP--KVTRSPP--ETAAPVEDMARRTKRPAPARPTMPPP 578
+ S + + V R +S KV+ +PP + AP ++A P P +P P
Sbjct: 510 RKIQSMGVRVMDTNWVARRGSSAGRKVSCAPPSMQPPAPPAELAAPLPSPLPEQPLDSP- 568
Query: 579 QVSGSRSSPPAPPLPPGSGSPGTPQALPRRLVGSSLRAPTVPPPLPPTPPQPARRQSRRS 638
+ SP L PG T ++ + +P QP + +
Sbjct: 569 --AAPALSPSGLGLQPGPERTSTTKSKELSPGSAQKGSPGSSQGTACAGTQPGAQPGAQP 626
Query: 639 PASPSPASPGPASPSPVSLSN--------PAQVDLG----AATAEGGAPEAISGVPTPPA 686
ASPSP+ P PA SP +L P +V G A G P +S PTPP+
Sbjct: 627 GASPSPSQP-PADQSPHTLRKVSKKLAPIPPKVPFGQPGAMADQSAGQPSPVSLSPTPPS 685
Query: 687 IP-----PQPRPRSLAS 698
P P+ SLAS
Sbjct: 686 TPSPYGLSYPQGYSLAS 702
Score = 43.9 bits (102), Expect = 5e-04
Identities = 47/181 (25%), Positives = 65/181 (35%), Gaps = 22/181 (12%)
Query: 464 SADTLFPGDINFNVSGLFSAVTLQDTVSDRLASEELPSTAVPT------PATTPAPAPAP 517
+A L P + ++ T +S A + P ++ T P P P
Sbjct: 569 AAPALSPSGLGLQPGPERTSTTKSKELSPGSAQKGSPGSSQGTACAGTQPGAQPGAQPGA 628
Query: 518 APAPA--PALASAATKERTESEVPPRPASPKVTRSPPETAAPVEDMARRTKRPAPARPTM 575
+P+P+ PA S T + ++ P P PKV P A +P P+
Sbjct: 629 SPSPSQPPADQSPHTLRKVSKKLAPIP--PKVPFGQPGAMADQSAGQPSPVSLSPTPPST 686
Query: 576 PPPQ----------VSGSRSSPPAPPLPPGSGSPGTPQALPRRLVGSSLRAPTVPPPLPP 625
P P SG S APPL S S T R + PT+PPP PP
Sbjct: 687 PSPYGLSYPQGYSLASGQLSPAAAPPL--ASPSVFTSTLSKSRPTPKPRQRPTLPPPQPP 744
Query: 626 T 626
T
Sbjct: 745 T 745
Score = 42.7 bits (99), Expect = 0.001
Identities = 39/115 (33%), Positives = 55/115 (47%), Gaps = 17/115 (14%)
Query: 490 VSDRLASEELPSTAVPTPATTPAPAPAPAPAPAPALASAATKERTESEVPPRPASPKVTR 549
++D+ A + P + PTP +TP+P P S A+ + + + PP ASP V
Sbjct: 666 MADQSAGQPSPVSLSPTPPSTPSPYGLSYPQGY----SLASGQLSPAAAPPL-ASPSVFT 720
Query: 550 SPPETAAPVEDMARRTKRPAPARPTMPPPQ---VSGSRSSPPAPPLPPGSG-SPG 600
S + P T +P RPT+PPPQ V+ S SSP + P G SPG
Sbjct: 721 STLSKSRP-------TPKPRQ-RPTLPPPQPPTVNLSASSPQSTEAPMLDGMSPG 767
>gi|23510413 sorting nexin 26 [Homo sapiens]
Length = 1126
Score = 121 bits (304), Expect = 2e-27
Identities = 127/477 (26%), Positives = 178/477 (37%), Gaps = 94/477 (19%)
Query: 272 RVYGVSLATHLQELGREIALPIEACVMMLLSEGMKEEGLFRLAAGASVLKRLKQTMASD- 330
RV+G L HL G+++ + C + + G+ + G++RL+ +S ++RL+ S+
Sbjct: 311 RVFGCDLGEHLSNSGQDVPQVLRCCSEFIEAHGVVD-GIYRLSGVSSNIQRLRHEFDSER 369
Query: 331 --PHSLEEFCSDPHAVAGALKSYLRELPEPLMTFDLYDDWMRAASLKEPGARLQALQEVC 388
S F D H+V+ K Y RELP PL+T+ LY + A S+ RL + +V
Sbjct: 370 IPELSGPAFLQDIHSVSSLCKLYFRELPNPLLTYQLYGKFSEAMSVPGEEERLVRVHDVI 429
Query: 389 SRLPPENLSNLRYLMKFLARLAEEQEVNKMTPSNIAIVLGPNLLWPPEKE----GDQAQL 444
+LPP + L YL++ LAR+A M N+AIV PNLL E E G A
Sbjct: 430 QQLPPPHYRTLEYLLRHLARMARHSANTSMHARNLAIVWAPNLLRSMELESVGMGGAAAF 489
Query: 445 DAASVSSIQVVGVVEALIQSADTLFPGDINFNVSGLFSAVTLQDTVSDRLASEELPSTAV 504
V S+ VVE L+ D LF F +GL + +
Sbjct: 490 REVRVQSV----VVEFLLTHVDVLFSD--TFTSAGL----------------DPAGRCLL 527
Query: 505 PTPATTPAPAPAPAPAPAPALASAATKERTESEVPPRPASPKVTRSPPETAAPVEDMARR 564
P P + P+ L A + + P P +PK SP E +R
Sbjct: 528 PRPKSLAGSCPS---TRLLTLEEAQARTQGRLGTPTEPTTPKAPASPAERRKGERGEKQR 584
Query: 565 --------------------TKRPAP-ARPTMPPPQVSGSR----------------SSP 587
K+P P T PPQ SGSR S
Sbjct: 585 KPGGSSWKTFFALGRGPSVPRKKPLPWLGGTRAPPQPSGSRPDTVTLRSAKSEESLSSQA 644
Query: 588 PAPPLPPGSGSPGTPQALPRRLVGSSLRAPTVP-------PPLPPTPPQPARRQSRRSPA 640
L G+P + P G SLR +P PL Q + R +
Sbjct: 645 SGAELLGAGGAPASATPTPALSPGRSLRPHLIPLLLRGAEAPLTDACQQEMCSKLRGAQG 704
Query: 641 SPSPASPGPASPSPVSLSNPAQVDLGAATAEGGAPEAISGVPTPPAIPPQPRPRSLA 697
P P P P+SL P GGAP P PP P + +LA
Sbjct: 705 PLGPDMESPLPPPPLSLLRP-----------GGAP------PPPPKNPARLMALALA 744
Score = 44.7 bits (104), Expect = 3e-04
Identities = 58/193 (30%), Positives = 78/193 (40%), Gaps = 34/193 (17%)
Query: 498 ELPSTAVPTPATTPAPAPAP---APAPAPALAS--AATKERTESEVPP--RPASPK-VTR 549
+ P A +P + P+ P P +PAP L K PP +P+SP V R
Sbjct: 850 DAPEAAAQSPCSVPSQVPTPGFFSPAPRECLPPFLGVPKPGLYPLGPPSFQPSSPAPVWR 909
Query: 550 SPPETAAPVE---------------DMARRTKRPAPARPTMPPPQVSGSRS----SPPAP 590
S AP++ + T+ +P R +MPP +++ S SPP
Sbjct: 910 SSLGPPAPLDRGENLYYEIGASEGSPYSGPTRSWSPFR-SMPPDRLNASYGMLGQSPPLH 968
Query: 591 PLPPGSGS-PGTPQALPRRLVGSSLRAPTVPPPLPPTPPQPARRQSRRSPASPSPASPGP 649
P S P P P +G S AP P PTPP+P P PSPAS
Sbjct: 969 RSPDFLLSYPPAPSCFPPDHLGYS--APQ-HPARRPTPPEPLYVNLALGPRGPSPASSSS 1025
Query: 650 ASP--SPVSLSNP 660
+SP P S S+P
Sbjct: 1026 SSPPAHPRSRSDP 1038
Score = 44.3 bits (103), Expect = 4e-04
Identities = 56/212 (26%), Positives = 74/212 (34%), Gaps = 29/212 (13%)
Query: 498 ELPSTAVPTPATTPAPAPAPAPAPAPALASAATKERTESEVPPRPASPKVTRSPPETAAP 557
E P P P AP P P L + A ER + +V + + + +PP + +P
Sbjct: 711 ESPLPPPPLSLLRPGGAPPPPPKNPARLMALALAERAQ-QVAEQQSQQECGGTPPASQSP 769
Query: 558 VEDMARRTKRPAPARPTMPPPQVSGSRSSPPAPPLPPGSGSPGTPQALPRRLVGSSLRAP 617
R P SGS PP PG+ PG P LPR+ SL
Sbjct: 770 FH-------RSLSLEVGGEPLGTSGS-GPPPNSLAHPGAWVPGPPPYLPRQQSDGSL--- 818
Query: 618 TVPPPLPPTPPQPARRQSRRSPASPSPA---------SPGPASPSPVSLSNPAQVDLGAA 668
L P R+ R PA S +P A+ SP S+ + +
Sbjct: 819 -----LRSQRPMGTSRRGLRGPAQVSAQLRAGGGGRDAPEAAAQSPCSVPSQVPTPGFFS 873
Query: 669 TAEGGAPEAISGVPTP---PAIPPQPRPRSLA 697
A GVP P P PP +P S A
Sbjct: 874 PAPRECLPPFLGVPKPGLYPLGPPSFQPSSPA 905
Score = 42.4 bits (98), Expect = 0.001
Identities = 46/172 (26%), Positives = 63/172 (36%), Gaps = 28/172 (16%)
Query: 539 PPRPASPKVTRS--PPETAAPVEDMARRTKRPAPARPTMPPPQVSGSRSSPPAPPLPPGS 596
PP SP S P + P + + + RPT P P P P P S
Sbjct: 965 PPLHRSPDFLLSYPPAPSCFPPDHLGYSAPQHPARRPTPPEPLYVNLALGPRGPS--PAS 1022
Query: 597 GSPGTPQALPRRLVGSSLRAPTVPPPLPPTPPQPARRQSRRSPASPS--PASPGPASP-- 652
S +P A PR + P PP P P ++++ P +P P GP P
Sbjct: 1023 SSSSSPPAHPR----------SRSDPGPPVPRLPQKQRAPWGPRTPHRVPGPWGPPEPLL 1072
Query: 653 ----SPVSLSNPAQVDLGAATAEGGAPEAISGVPTPPAIPPQPRPR-SLASE 699
+P + ++ G+ GG +G P PP P P SL SE
Sbjct: 1073 LYRAAPPAYGRGGELHRGSLYRNGGQRGEGAGPP-----PPYPTPSWSLHSE 1119
Score = 30.4 bits (67), Expect = 5.8
Identities = 31/129 (24%), Positives = 42/129 (32%), Gaps = 30/129 (23%)
Query: 515 PAPAPAPAPALASAATKERTESEVPPRPASPKVTRSPPETAAPVEDMARRTKRPAPARPT 574
PAP+ P L +A + PP P + P + P+PA +
Sbjct: 979 PAPSCFPPDHLGYSAPQHPARRPTPPEPLYVNLALGP--------------RGPSPASSS 1024
Query: 575 MPPPQVSGSRSSPPAPP---LPPGSGSPGTPQALPRRLVGSSLRAPTVPPPLPPTPPQPA 631
P S P PP LP +P P+ P R+ G P PP+P
Sbjct: 1025 SSSPPAHPRSRSDPGPPVPRLPQKQRAPWGPRT-PHRVPG------------PWGPPEPL 1071
Query: 632 RRQSRRSPA 640
PA
Sbjct: 1072 LLYRAAPPA 1080
>gi|156071465 Rho GTPase activating protein 4 [Homo sapiens]
Length = 946
Score = 112 bits (279), Expect = 2e-24
Identities = 102/447 (22%), Positives = 182/447 (40%), Gaps = 28/447 (6%)
Query: 80 TMAESFKELDPDSSMGKALEMSCAI-------------QNQLARILAEFEMTLERDVLQP 126
++ E+ + LDP K LE+ + +++A I E E+ RD + P
Sbjct: 304 SLEEAVEALDPPGDKAKVLEVHATVFCPPLRFDYHPHDGDEVAEICVEMEL---RDEILP 360
Query: 127 LSRLSEEELPAILKHKKSLQKLVSDWNTLKSRLSQATKNSGSSQGLGGSPGSHSHTTMAN 186
++ + L + + K TLK+ L + S G S +T +
Sbjct: 361 RAQNIQSRLDRQTIETEEVNK------TLKATLQALLEVVASDDGDVLDSFQTSPSTESL 414
Query: 187 KVETLKEEEEELKRKVEQCRDE---YLADLYHFVTKEDSYANYFIRLLEIQADYHRRSLS 243
K + + R+ Q ++ YL L +++ A + ++Q R
Sbjct: 415 KSTSSDPGSRQAGRRRGQQQETETFYLTKLQEYLSGRSILAKLQAKHEKLQEALQRGDKE 474
Query: 244 SLDTALAELRENHGQADHSPSMTATHFPRVYGVSLATHLQELGREIALPIEACVMMLLSE 303
+ + + + Q P ++ + R++G + +Q G+ + L +E+C+ +
Sbjct: 475 EQEVSWTQYTQRKFQKSRQPRPSSQYNQRLFGGDMEKFIQSSGQPVPLVVESCIRFINLN 534
Query: 304 GMKEEGLFRLAAGASVLKRLKQTMASDPHSLEEFCS--DPHAVAGALKSYLRELPEPLMT 361
G++ EG+FR++ + ++ L E C+ D +VAG LK Y R L PL
Sbjct: 535 GLQHEGIFRVSGAQLRVSEIRDAFERGEDPLVEGCTAHDLDSVAGVLKLYFRSLEPPLFP 594
Query: 362 FDLYDDWMRAASLKEPGARLQALQEVCSRLPPENLSNLRYLMKFLARLAEEQEVNKMTPS 421
DL+ + + ++ L+ R++ + + RLP L LRYL FL LA+ + N M P
Sbjct: 595 PDLFGELLASSELEATAERVEHVSRLLWRLPAPVLVVLRYLFTFLNHLAQYSDENMMDPY 654
Query: 422 NIAIVLGPNLLWPPEKEGDQAQLDAASVSSIQVVGVVEALIQSADTLFPGDINFNVSGLF 481
N+A+ GP LL P + D L +Q + V + T PG +
Sbjct: 655 NLAVCFGPTLLPVPAGQ-DPVALQGRVNQLVQTLIVQPDRVFPPLTSLPGPVYEKCMAPP 713
Query: 482 SAVTLQDTVSDRLASEELPSTAVPTPA 508
SA L D + L ++ P PA
Sbjct: 714 SASCLGDAQLESLGADNEPELEAEMPA 740
>gi|4502813 chimerin (chimaerin) 1 isoform a [Homo sapiens]
Length = 459
Score = 109 bits (273), Expect = 8e-24
Identities = 66/206 (32%), Positives = 109/206 (52%), Gaps = 12/206 (5%)
Query: 269 HFPRVYGVSLATHLQELGREIALPIEACVMMLLSEGMKEEGLFRLAAGASVLKRLKQTMA 328
H +VY L T ++ + + ++ C+ + S G+ EGL+R++ + +++ +K
Sbjct: 261 HVKKVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFD 320
Query: 329 SDPHSLE---EFCSDPHAVAGALKSYLRELPEPLMTFDLYDDWMRAASLKEPGARLQALQ 385
D + D + + GALK Y R+LP PL+T+D Y ++ +A + +P +L+ L
Sbjct: 321 RDGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLH 380
Query: 386 EVCSRLPPENLSNLRYLMKFLARLAEEQEVNKMTPSNIAIVLGPNLLWPPEKEGDQAQLD 445
E LPP + LRYLM L R+ ++ N M N+ IV GP L+ PE LD
Sbjct: 381 EALKLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPE-------LD 433
Query: 446 A-ASVSSIQVVG-VVEALIQSADTLF 469
A A+++ I+ VVE LI++ D LF
Sbjct: 434 AMAALNDIRYQRLVVELLIKNEDILF 459
>gi|209364623 chimerin (chimaerin) 1 isoform b [Homo sapiens]
Length = 433
Score = 109 bits (273), Expect = 8e-24
Identities = 66/206 (32%), Positives = 109/206 (52%), Gaps = 12/206 (5%)
Query: 269 HFPRVYGVSLATHLQELGREIALPIEACVMMLLSEGMKEEGLFRLAAGASVLKRLKQTMA 328
H +VY L T ++ + + ++ C+ + S G+ EGL+R++ + +++ +K
Sbjct: 235 HVKKVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFD 294
Query: 329 SDPHSLE---EFCSDPHAVAGALKSYLRELPEPLMTFDLYDDWMRAASLKEPGARLQALQ 385
D + D + + GALK Y R+LP PL+T+D Y ++ +A + +P +L+ L
Sbjct: 295 RDGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLH 354
Query: 386 EVCSRLPPENLSNLRYLMKFLARLAEEQEVNKMTPSNIAIVLGPNLLWPPEKEGDQAQLD 445
E LPP + LRYLM L R+ ++ N M N+ IV GP L+ PE LD
Sbjct: 355 EALKLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPE-------LD 407
Query: 446 A-ASVSSIQVVG-VVEALIQSADTLF 469
A A+++ I+ VVE LI++ D LF
Sbjct: 408 AMAALNDIRYQRLVVELLIKNEDILF 433
>gi|229094128 active breakpoint cluster region-related protein
isoform c [Homo sapiens]
Length = 813
Score = 108 bits (270), Expect = 2e-23
Identities = 62/192 (32%), Positives = 104/192 (54%), Gaps = 2/192 (1%)
Query: 273 VYGVSLATHLQELGREIALPIEACVMMLLSEGMKEEGLFRLAAGASVLKRLKQTMASDPH 332
V+GV ++ + ++ + CV + G++E G++R++ A+ ++ LK ++
Sbjct: 598 VFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNK 657
Query: 333 SLEEFCSDP--HAVAGALKSYLRELPEPLMTFDLYDDWMRAASLKEPGARLQALQEVCSR 390
+ SD +A+AG LK Y RELPEPL+T LY +M +L +P A+ + +
Sbjct: 658 DILLMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLLRS 717
Query: 391 LPPENLSNLRYLMKFLARLAEEQEVNKMTPSNIAIVLGPNLLWPPEKEGDQAQLDAASVS 450
LP NL +L++ L R+AE++ +NKM+ N+A V GP LL P E E AA +
Sbjct: 718 LPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSEVESKAHLTSAADIW 777
Query: 451 SIQVVGVVEALI 462
S V+ V+ L+
Sbjct: 778 SHDVMAQVQVLL 789
>gi|38679957 active breakpoint cluster region-related protein
isoform a [Homo sapiens]
Length = 859
Score = 108 bits (270), Expect = 2e-23
Identities = 62/192 (32%), Positives = 104/192 (54%), Gaps = 2/192 (1%)
Query: 273 VYGVSLATHLQELGREIALPIEACVMMLLSEGMKEEGLFRLAAGASVLKRLKQTMASDPH 332
V+GV ++ + ++ + CV + G++E G++R++ A+ ++ LK ++
Sbjct: 644 VFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNK 703
Query: 333 SLEEFCSDP--HAVAGALKSYLRELPEPLMTFDLYDDWMRAASLKEPGARLQALQEVCSR 390
+ SD +A+AG LK Y RELPEPL+T LY +M +L +P A+ + +
Sbjct: 704 DILLMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLLRS 763
Query: 391 LPPENLSNLRYLMKFLARLAEEQEVNKMTPSNIAIVLGPNLLWPPEKEGDQAQLDAASVS 450
LP NL +L++ L R+AE++ +NKM+ N+A V GP LL P E E AA +
Sbjct: 764 LPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSEVESKAHLTSAADIW 823
Query: 451 SIQVVGVVEALI 462
S V+ V+ L+
Sbjct: 824 SHDVMAQVQVLL 835
>gi|38679954 active breakpoint cluster region-related protein
isoform b [Homo sapiens]
Length = 822
Score = 108 bits (270), Expect = 2e-23
Identities = 62/192 (32%), Positives = 104/192 (54%), Gaps = 2/192 (1%)
Query: 273 VYGVSLATHLQELGREIALPIEACVMMLLSEGMKEEGLFRLAAGASVLKRLKQTMASDPH 332
V+GV ++ + ++ + CV + G++E G++R++ A+ ++ LK ++
Sbjct: 607 VFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNK 666
Query: 333 SLEEFCSDP--HAVAGALKSYLRELPEPLMTFDLYDDWMRAASLKEPGARLQALQEVCSR 390
+ SD +A+AG LK Y RELPEPL+T LY +M +L +P A+ + +
Sbjct: 667 DILLMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLLRS 726
Query: 391 LPPENLSNLRYLMKFLARLAEEQEVNKMTPSNIAIVLGPNLLWPPEKEGDQAQLDAASVS 450
LP NL +L++ L R+AE++ +NKM+ N+A V GP LL P E E AA +
Sbjct: 727 LPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSEVESKAHLTSAADIW 786
Query: 451 SIQVVGVVEALI 462
S V+ V+ L+
Sbjct: 787 SHDVMAQVQVLL 798
>gi|34013590 Rho GTPase activating protein 2 [Homo sapiens]
Length = 698
Score = 106 bits (265), Expect = 6e-23
Identities = 126/463 (27%), Positives = 180/463 (38%), Gaps = 67/463 (14%)
Query: 269 HFPRVYGVSLATHLQELGREIALPIEACVMMLLSEGMKEEGLFRLAAGASVLKRLKQTMA 328
H R YG LA L +E CV + G+ EEGLFR+ A++++ L+ +
Sbjct: 162 HHERKYGPRLAPLL----------VEQCVDFIRERGLTEEGLFRMPGQANLVRDLQDSFD 211
Query: 329 SDPHSLEEFCSDPHAVAGALKSYLRELPEPLMTFDLYDDWMRAASL--KEPGARLQALQE 386
L + +D H VA LK YLRELPEP++ F Y+D++ A L K+ G L +
Sbjct: 212 CGEKPLFDSTTDVHTVASLLKLYLRELPEPVVPFARYEDFLSCAQLLTKDEGEGTLELAK 271
Query: 387 VCSRLPPENLSNLRYLMKFLARLAEEQEVNKMTPSNIAIVLGPNLLWPPEKEGDQAQLDA 446
S LP N + LRY+ KFL + VNKM+ N+A V GPN+L P+ E ++
Sbjct: 272 QVSNLPQANYNLLRYICKFLDEVQAYSNVNKMSVQNLATVFGPNIL-RPQVEDPVTIMEG 330
Query: 447 ASVSSIQVVGVVEALIQSADTLFPGDINFNVS----GLFSAVTLQDTVSDRLASEELPST 502
S+ V ++ LI+ LF + + GL AV SEE+
Sbjct: 331 TSL----VQHLMTVLIRKHSQLFTAPVPEGPTSPRGGLQCAV--------GWGSEEVTRD 378
Query: 503 AVPTPATTPAPAPAPAPAPAPALASAATKERTESEVPPRPASP-KVTRSPPETAAPVEDM 561
+ P PA + A+ A RT P SP K ++ P +
Sbjct: 379 SQGEPGGPGLPAHRTSSLDG---AAVAVLSRTAPTGPGSRCSPGKKVQTLPSWKSSFRQP 435
Query: 562 ARRTKRPAPARPTMPPPQVS--------------GSRSSPPAPPLPPGSGS--------- 598
+ P ++ P +S G R + L SGS
Sbjct: 436 RSLSGSPKGGGSSLEVPIISSGGNWLMNGLSSLRGHRRASSGDRL-KDSGSVQRLSTYDN 494
Query: 599 -------PGTPQALPRRLVGSSLRAPTVPPPLPPTPPQPARRQSRRSPASPSPASPGPAS 651
PG P G+S +V L A S RS A S
Sbjct: 495 VPAPGLVPGIPSVASMAWSGASSSESSVGGSLSSCTACRASDSSARSSLHTDWAL--EPS 552
Query: 652 PSPVSLSNPAQVDLGAATAEGGAPEAISGVPTPPAIPPQPRPR 694
P P S +P +DL + E GA A + P+ P P + R
Sbjct: 553 PLPSSSEDPKSLDLDHSMDEAGA-GASNSEPSEPDSPTREHAR 594
>gi|111154090 Rho GTPase activating protein 24 isoform 3 [Homo
sapiens]
Length = 653
Score = 106 bits (264), Expect = 8e-23
Identities = 67/182 (36%), Positives = 98/182 (53%), Gaps = 7/182 (3%)
Query: 293 IEACVMMLLSEGMKEEGLFRLAAGASVLKRLKQTMASDPHSLEEFCSDPHAVAGALKSYL 352
+E CV + G+KEEGLFRL A+++K L+ + +D H VA LK YL
Sbjct: 61 VEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFDSNTDVHTVASLLKLYL 120
Query: 353 RELPEPLMTFDLYDDWMRAASL--KEPGARLQALQEVCSRLPPENLSNLRYLMKFLARLA 410
RELPEP++ + Y+D++ A L KE A ++ L + LP N + L+Y+ +FL +
Sbjct: 121 RELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNLLKYICRFLDEVQ 180
Query: 411 EEQEVNKMTPSNIAIVLGPNLLWPPEKEGDQAQLDAASVSSIQVVGVVEALIQSADTLFP 470
VNKM+ N+A V GPN+L P K D + +V Q++ V +I D LFP
Sbjct: 181 SYSGVNKMSVQNLATVFGPNILRP--KVEDPLTIMEGTVVVQQLMSV---MISKHDCLFP 235
Query: 471 GD 472
D
Sbjct: 236 KD 237
>gi|111154099 Rho GTPase activating protein 24 isoform 2 [Homo
sapiens]
Length = 655
Score = 106 bits (264), Expect = 8e-23
Identities = 67/182 (36%), Positives = 98/182 (53%), Gaps = 7/182 (3%)
Query: 293 IEACVMMLLSEGMKEEGLFRLAAGASVLKRLKQTMASDPHSLEEFCSDPHAVAGALKSYL 352
+E CV + G+KEEGLFRL A+++K L+ + +D H VA LK YL
Sbjct: 63 VEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFDSNTDVHTVASLLKLYL 122
Query: 353 RELPEPLMTFDLYDDWMRAASL--KEPGARLQALQEVCSRLPPENLSNLRYLMKFLARLA 410
RELPEP++ + Y+D++ A L KE A ++ L + LP N + L+Y+ +FL +
Sbjct: 123 RELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNLLKYICRFLDEVQ 182
Query: 411 EEQEVNKMTPSNIAIVLGPNLLWPPEKEGDQAQLDAASVSSIQVVGVVEALIQSADTLFP 470
VNKM+ N+A V GPN+L P K D + +V Q++ V +I D LFP
Sbjct: 183 SYSGVNKMSVQNLATVFGPNILRP--KVEDPLTIMEGTVVVQQLMSV---MISKHDCLFP 237
Query: 471 GD 472
D
Sbjct: 238 KD 239
>gi|111154092 Rho GTPase activating protein 24 isoform 1 [Homo
sapiens]
Length = 748
Score = 106 bits (264), Expect = 8e-23
Identities = 67/182 (36%), Positives = 98/182 (53%), Gaps = 7/182 (3%)
Query: 293 IEACVMMLLSEGMKEEGLFRLAAGASVLKRLKQTMASDPHSLEEFCSDPHAVAGALKSYL 352
+E CV + G+KEEGLFRL A+++K L+ + +D H VA LK YL
Sbjct: 156 VEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFDSNTDVHTVASLLKLYL 215
Query: 353 RELPEPLMTFDLYDDWMRAASL--KEPGARLQALQEVCSRLPPENLSNLRYLMKFLARLA 410
RELPEP++ + Y+D++ A L KE A ++ L + LP N + L+Y+ +FL +
Sbjct: 216 RELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNLLKYICRFLDEVQ 275
Query: 411 EEQEVNKMTPSNIAIVLGPNLLWPPEKEGDQAQLDAASVSSIQVVGVVEALIQSADTLFP 470
VNKM+ N+A V GPN+L P K D + +V Q++ V +I D LFP
Sbjct: 276 SYSGVNKMSVQNLATVFGPNILRP--KVEDPLTIMEGTVVVQQLMSV---MISKHDCLFP 330
Query: 471 GD 472
D
Sbjct: 331 KD 332
>gi|21314774 T-cell activation Rho GTPase-activating protein isoform
b [Homo sapiens]
Length = 731
Score = 105 bits (263), Expect = 1e-22
Identities = 105/376 (27%), Positives = 170/376 (45%), Gaps = 33/376 (8%)
Query: 292 PIEACVMMLLSEGMKEEGLFRLAAGASVLKRLKQTMAS-DPHSLEEFCSDPHAVAGALKS 350
PI+ + +L +G EG+FR AA K LK+ + S D LE H +A K
Sbjct: 103 PIQDILTILCLKGPSTEGIFRRAANEKARKELKEELNSGDAVDLERL--PVHLLAVVFKD 160
Query: 351 YLRELPEPLMTFDLYDDWMRAASLKEPGARLQALQEVCSRLPPENLSNLRYLMKFLARLA 410
+LR +P L++ DL+++WM A +++ R++AL++V +LP NL L++L+ L ++
Sbjct: 161 FLRSIPRKLLSSDLFEEWMGALEMQDEEDRIEALKQVADKLPRPNLLLLKHLVYVLHLIS 220
Query: 411 EEQEVNKMTPSNIAIVLGPNLLWPPEKEGDQA-QLDAASVSSIQVVGVVEALIQSADTLF 469
+ EVN+M SN+AI +GPN+L E DQ+ +A + +V +VE LI + +F
Sbjct: 221 KNSEVNRMDSSNLAICIGPNML---TLENDQSLSFEAQKDLNNKVKTLVEFLIDNCFEIF 277
Query: 470 PGDINFNVSGLFSAVTLQDTVSDRLAS----EELPSTAVPTPATTPAPAPAPAPAPAPAL 525
+I + S + S +L+ T S +++ S + + + +P+ P +
Sbjct: 278 GENIPVH-SSITSDDSLEHTDSSDVSTLQNDSAYDSNDPDVESNSSSGISSPSRQPQVPM 336
Query: 526 ASAATKE----RTESEVPPRPASPKVTRSPPETAAPVEDMARRTKRPAPARPTMPPPQVS 581
A+AA + + EV P P V R A P RR + P+MP Q
Sbjct: 337 ATAAGLDSAGPQDAREVSPEPIVSTVARLKSSLAQP----DRRY-----SEPSMPSSQ-E 386
Query: 582 GSRSSPPAPPLPPGSGSPGTPQALPRRLVGSSLRAPTVPPPLPPTPPQPARRQSRRSPAS 641
S L G P+ VGS L + P P PA + + P
Sbjct: 387 CLESRVTNQTLTKSEGDFPVPR------VGSRLESEEAEDPF-PEEVFPAVQGKTKRPVD 439
Query: 642 PSPASPGPASPSPVSL 657
+ P S P +L
Sbjct: 440 LKIKNLAPGSVLPRAL 455
>gi|186928844 Cdc42 GTPase-activating protein [Homo sapiens]
Length = 1444
Score = 105 bits (262), Expect = 1e-22
Identities = 77/273 (28%), Positives = 126/273 (46%), Gaps = 24/273 (8%)
Query: 274 YGVSLATHLQELGREIALPIEACVMMLLSEGMKEEGLFRLAAGASVLKRLKQTMASDPH- 332
+G L +L+ G+++ +++C + + G+ + G++RL+ S ++RL+Q SD
Sbjct: 19 FGCDLTEYLESSGQDVPYVLKSCAEFIETHGIVD-GIYRLSGVTSNIQRLRQEFGSDQCP 77
Query: 333 --SLEEFCSDPHAVAGALKSYLRELPEPLMTFDLYDDWMRAASLKEPGARLQALQEVCSR 390
+ E + D H V K Y RELP PL+T++LY+ + A S +L +Q V
Sbjct: 78 DLTREVYLQDIHCVGSLCKLYFRELPNPLLTYELYEKFTEAVSHCPEEGQLARIQNVIQE 137
Query: 391 LPPENLSNLRYLMKFLARLAEEQEVNKMTPSNIAIVLGPNLLWPPEKEGDQAQLDAASVS 450
LPP + L YL++ LA +A M N+A+V PNLL E E DAA ++
Sbjct: 138 LPPSHYRTLEYLIRHLAHIASFSSKTNMHARNLALVWAPNLLRSKEIEATGCNGDAAFLA 197
Query: 451 SIQVVGVVEALIQSADTLF----PGDINFNVSGLFSAVTLQDTVSDRLASEELPSTAVPT 506
V+E ++ D +F PG + D + S LP+ ++P
Sbjct: 198 VRVQQVVIEFILNHVDQIFNNGAPGSLE------------NDENRPIMKSLTLPALSLPM 245
Query: 507 PATTPAPAPAPAPAPAPALASAATKERTESEVP 539
+ A A + A A KER E+ +P
Sbjct: 246 KLV----SLEEAQARSLATNHPARKERRENSLP 274
Score = 38.9 bits (89), Expect = 0.016
Identities = 43/144 (29%), Positives = 56/144 (38%), Gaps = 24/144 (16%)
Query: 558 VEDMARRTKRPAPARPTMPPPQVSGSRSSPPAPPLPPGSGSPGTPQALPRRLVGSSLRAP 617
+E + P PA T P + S P P PPGS L S AP
Sbjct: 663 IESEEELSSLPPPALKTSPIQPILESSLGPFIPSEPPGS------------LPCGSFPAP 710
Query: 618 TVPPPLPPTPPQPARRQSRRSPASPSPASPGP--------ASPSPVSLSNPAQVDLGAAT 669
V PL PA + ++ + + S P P AS +P+ + P + AT
Sbjct: 711 -VSTPLEVWTRDPANQSTQGASTAASREKPEPEQGLHPDLASLAPLEIV-PFEKASPQAT 768
Query: 670 AEGGAPEAISGVPTPPAIPPQPRP 693
E G P +S P PPA PP P P
Sbjct: 769 VEVGGPGNLS-PPLPPA-PPPPTP 790
Score = 31.2 bits (69), Expect = 3.4
Identities = 31/121 (25%), Positives = 42/121 (34%), Gaps = 16/121 (13%)
Query: 521 PAPALASAATKERTESEVPP-----RPASPKVTRSPPETAAPVEDMARRTKRPAPARPTM 575
P PAL ++ + ES + P P S P + P+E R PA +
Sbjct: 673 PPPALKTSPIQPILESSLGPFIPSEPPGSLPCGSFPAPVSTPLEVWTRD-----PANQST 727
Query: 576 PPPQVSGSRSSP-PAPPLPPGSGSPGTPQALPRRLVGSSLRAPT-----VPPPLPPTPPQ 629
+ SR P P L P S + +P + PPLPP PP
Sbjct: 728 QGASTAASREKPEPEQGLHPDLASLAPLEIVPFEKASPQATVEVGGPGNLSPPLPPAPPP 787
Query: 630 P 630
P
Sbjct: 788 P 788
>gi|218083800 Rho GTPase-activating protein isoform 1 [Homo sapiens]
Length = 2087
Score = 103 bits (258), Expect = 4e-22
Identities = 70/207 (33%), Positives = 107/207 (51%), Gaps = 6/207 (2%)
Query: 272 RVYGVSLATHLQELGREIALPIEACVMMLLSEGMKEEGLFRLAAGASVLKRLKQTMASD- 330
RV+G L HL G E+ +++C + G+ + G++RL+ AS ++RL+ S+
Sbjct: 368 RVFGCDLGEHLLNSGFEVPQVLQSCTAFIERYGIVD-GIYRLSGVASNIQRLRHEFDSEH 426
Query: 331 --PHSLEEFCSDPHAVAGALKSYLRELPEPLMTFDLYDDWMRAASLKEPGARLQALQEVC 388
+ E + D H+V K Y RELP PL+T+ LY+ + A S RL + +V
Sbjct: 427 VPDLTKEPYVQDIHSVGSLCKLYFRELPNPLLTYQLYEKFSDAVSAATDEERLIKIHDVI 486
Query: 389 SRLPPENLSNLRYLMKFLARLAEEQEVNKMTPSNIAIVLGPNLLWPPEKEGDQAQLDAAS 448
+LPP + L +LM+ L+ LA+ + M N+AIV PNLL + E AA
Sbjct: 487 QQLPPPHYRTLEFLMRHLSLLADYCSITNMHAKNLAIVWAPNLLRSKQIESACFSGTAAF 546
Query: 449 VS-SIQVVGVVEALIQSADTLFPGDIN 474
+ IQ V VVE ++ D LF G I+
Sbjct: 547 MEVRIQSV-VVEFILNHVDVLFSGRIS 572
Score = 36.6 bits (83), Expect = 0.081
Identities = 49/207 (23%), Positives = 76/207 (36%), Gaps = 31/207 (14%)
Query: 505 PTPATTPA-----PAPAPAPAPAPALASAATKERTESEVPPRPASPKVTRSPP--ETAAP 557
PTP P+ P+ +P + A + T +++ + AS V P + AA
Sbjct: 1235 PTPPNLPSDKIYPPSGSPEENTSTATMTYMTTTPATAQMSTKEASWDVAEQPTTADFAAA 1294
Query: 558 VEDMARRTKRPAPARPTMPPPQVSGSRSSPPAPPLPPGSGSPGTPQALPRRLVGSSLRAP 617
RT RP +PPP S PP G QA + +S +
Sbjct: 1295 TLQRTHRTNRP------LPPPPSQRSAEQPPV---------VGQVQAATNIGLNNSHKVQ 1339
Query: 618 TVPPPLPPTPPQPARRQSRRSPASPSPASPGPASPSPVSLSNPAQVDLGAATAEGGAPEA 677
V P+P PP+P ++ PAS + G A+ + ++ Q L +G
Sbjct: 1340 GV-VPVPERPPEP---RAMDDPASAFISDSG-AAAAQCPMATAVQPGLPEKVRDGARVPL 1394
Query: 678 I----SGVPTPPAIPPQPRPRSLASET 700
+ VP P P P P + E+
Sbjct: 1395 LHLRAESVPAHPCGFPAPLPPTRMMES 1421
Score = 35.0 bits (79), Expect = 0.24
Identities = 45/173 (26%), Positives = 61/173 (35%), Gaps = 25/173 (14%)
Query: 486 LQDTVSDRLASEELPSTAVPTPATTPAPAPAPAPAPAPALASAATKERTESEVPPRPASP 545
+ + +D +S S + + P P P P P AS T V A P
Sbjct: 1427 IHSSSADATSSSNYHSFVTASSTSVDDALPLPLPVPQPKHASQKT-------VYSSFARP 1479
Query: 546 KVTRSP--PETAAPVEDMARRTKRPAPARP---TMPPPQVSGSRSSPPAPP-------LP 593
VT P P+ RP P + QV G+RS PPA +
Sbjct: 1480 DVTTEPFGPDNCLHFNMTPNCQYRPQSVPPHHNKLEQHQVYGARSEPPASMGLRYNTYVA 1539
Query: 594 PGSGSPGTPQALPRRL-----VGSSLRAPTVPPPLPPTPPQPARRQSRRSPAS 641
PG + G R+ + SS+R P +PP P R QS +P S
Sbjct: 1540 PGRNASGHHSKPCSRVEYVSSLSSSVRNTCYPEDIPPY-PTIRRVQSLHAPPS 1591
>gi|29469071 Rho GTPase-activating protein isoform 2 [Homo sapiens]
Length = 1738
Score = 103 bits (258), Expect = 4e-22
Identities = 70/207 (33%), Positives = 107/207 (51%), Gaps = 6/207 (2%)
Query: 272 RVYGVSLATHLQELGREIALPIEACVMMLLSEGMKEEGLFRLAAGASVLKRLKQTMASD- 330
RV+G L HL G E+ +++C + G+ + G++RL+ AS ++RL+ S+
Sbjct: 19 RVFGCDLGEHLLNSGFEVPQVLQSCTAFIERYGIVD-GIYRLSGVASNIQRLRHEFDSEH 77
Query: 331 --PHSLEEFCSDPHAVAGALKSYLRELPEPLMTFDLYDDWMRAASLKEPGARLQALQEVC 388
+ E + D H+V K Y RELP PL+T+ LY+ + A S RL + +V
Sbjct: 78 VPDLTKEPYVQDIHSVGSLCKLYFRELPNPLLTYQLYEKFSDAVSAATDEERLIKIHDVI 137
Query: 389 SRLPPENLSNLRYLMKFLARLAEEQEVNKMTPSNIAIVLGPNLLWPPEKEGDQAQLDAAS 448
+LPP + L +LM+ L+ LA+ + M N+AIV PNLL + E AA
Sbjct: 138 QQLPPPHYRTLEFLMRHLSLLADYCSITNMHAKNLAIVWAPNLLRSKQIESACFSGTAAF 197
Query: 449 VS-SIQVVGVVEALIQSADTLFPGDIN 474
+ IQ V VVE ++ D LF G I+
Sbjct: 198 MEVRIQSV-VVEFILNHVDVLFSGRIS 223
Score = 36.6 bits (83), Expect = 0.081
Identities = 49/207 (23%), Positives = 76/207 (36%), Gaps = 31/207 (14%)
Query: 505 PTPATTPA-----PAPAPAPAPAPALASAATKERTESEVPPRPASPKVTRSPP--ETAAP 557
PTP P+ P+ +P + A + T +++ + AS V P + AA
Sbjct: 886 PTPPNLPSDKIYPPSGSPEENTSTATMTYMTTTPATAQMSTKEASWDVAEQPTTADFAAA 945
Query: 558 VEDMARRTKRPAPARPTMPPPQVSGSRSSPPAPPLPPGSGSPGTPQALPRRLVGSSLRAP 617
RT RP +PPP S PP G QA + +S +
Sbjct: 946 TLQRTHRTNRP------LPPPPSQRSAEQPPV---------VGQVQAATNIGLNNSHKVQ 990
Query: 618 TVPPPLPPTPPQPARRQSRRSPASPSPASPGPASPSPVSLSNPAQVDLGAATAEGGAPEA 677
V P+P PP+P ++ PAS + G A+ + ++ Q L +G
Sbjct: 991 GV-VPVPERPPEP---RAMDDPASAFISDSG-AAAAQCPMATAVQPGLPEKVRDGARVPL 1045
Query: 678 I----SGVPTPPAIPPQPRPRSLASET 700
+ VP P P P P + E+
Sbjct: 1046 LHLRAESVPAHPCGFPAPLPPTRMMES 1072
Score = 35.0 bits (79), Expect = 0.24
Identities = 45/173 (26%), Positives = 61/173 (35%), Gaps = 25/173 (14%)
Query: 486 LQDTVSDRLASEELPSTAVPTPATTPAPAPAPAPAPAPALASAATKERTESEVPPRPASP 545
+ + +D +S S + + P P P P P AS T V A P
Sbjct: 1078 IHSSSADATSSSNYHSFVTASSTSVDDALPLPLPVPQPKHASQKT-------VYSSFARP 1130
Query: 546 KVTRSP--PETAAPVEDMARRTKRPAPARP---TMPPPQVSGSRSSPPAPP-------LP 593
VT P P+ RP P + QV G+RS PPA +
Sbjct: 1131 DVTTEPFGPDNCLHFNMTPNCQYRPQSVPPHHNKLEQHQVYGARSEPPASMGLRYNTYVA 1190
Query: 594 PGSGSPGTPQALPRRL-----VGSSLRAPTVPPPLPPTPPQPARRQSRRSPAS 641
PG + G R+ + SS+R P +PP P R QS +P S
Sbjct: 1191 PGRNASGHHSKPCSRVEYVSSLSSSVRNTCYPEDIPPY-PTIRRVQSLHAPPS 1242
>gi|82546845 breakpoint cluster region isoform 2 [Homo sapiens]
Length = 1227
Score = 102 bits (255), Expect = 9e-22
Identities = 62/197 (31%), Positives = 104/197 (52%), Gaps = 7/197 (3%)
Query: 273 VYGVSLATHLQELGREIALPIEACVMMLLSEGMKEEGLFRLAAGASVLKRLKQTMASDPH 332
V+GV +A + ++ + CV + GM+E G++R++ A+ ++ LK +
Sbjct: 1007 VFGVKIAVVTKRERSKVPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQALKAAFDVNNK 1066
Query: 333 SLEEFCS--DPHAVAGALKSYLRELPEPLMTFDLYDDWMRAASLKEPGARLQALQEVCSR 390
+ S D +A+AG LK Y RELPEPL T + Y ++ +L +P A+ + +
Sbjct: 1067 DVSVMMSEMDVNAIAGTLKLYFRELPEPLFTDEFYPNFAEGIALSDPVAKESCMLNLLLS 1126
Query: 391 LPPENLSNLRYLMKFLARLAEEQEVNKMTPSNIAIVLGPNLLWPPEKEGDQAQLDAASVS 450
LP NL +L+ L R+AE++ VNKM+ N+A V GP LL P EKE + ++
Sbjct: 1127 LPEANLLTFLFLLDHLKRVAEKEAVNKMSLHNLATVFGPTLLRPSEKESKLPANPSQPIT 1186
Query: 451 -----SIQVVGVVEALI 462
S++V+ V+ L+
Sbjct: 1187 MTDSWSLEVMSQVQVLL 1203
Score = 30.8 bits (68), Expect = 4.5
Identities = 29/99 (29%), Positives = 35/99 (35%), Gaps = 17/99 (17%)
Query: 508 ATTPAPAPAPAPAPAPALASAATKERTESEVPPRPASPKVTRSPPETAAPVEDMARRTKR 567
A+ P PAPA P PA A R + E P A P R P A+ D
Sbjct: 94 ASRPQPAPADGADPPPAEEPEA---RPDGEGSPGKARPGTARRPGAAASGERD------- 143
Query: 568 PAPARPTMPPPQVSGSRSSPPAPPLPPGSGSPGTPQALP 606
PP V+ RS+ + G G PG P
Sbjct: 144 -----DRGPPASVAALRSN--FERIRKGHGQPGADAEKP 175
>gi|82546843 breakpoint cluster region isoform 1 [Homo sapiens]
Length = 1271
Score = 102 bits (255), Expect = 9e-22
Identities = 62/197 (31%), Positives = 104/197 (52%), Gaps = 7/197 (3%)
Query: 273 VYGVSLATHLQELGREIALPIEACVMMLLSEGMKEEGLFRLAAGASVLKRLKQTMASDPH 332
V+GV +A + ++ + CV + GM+E G++R++ A+ ++ LK +
Sbjct: 1051 VFGVKIAVVTKRERSKVPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQALKAAFDVNNK 1110
Query: 333 SLEEFCS--DPHAVAGALKSYLRELPEPLMTFDLYDDWMRAASLKEPGARLQALQEVCSR 390
+ S D +A+AG LK Y RELPEPL T + Y ++ +L +P A+ + +
Sbjct: 1111 DVSVMMSEMDVNAIAGTLKLYFRELPEPLFTDEFYPNFAEGIALSDPVAKESCMLNLLLS 1170
Query: 391 LPPENLSNLRYLMKFLARLAEEQEVNKMTPSNIAIVLGPNLLWPPEKEGDQAQLDAASVS 450
LP NL +L+ L R+AE++ VNKM+ N+A V GP LL P EKE + ++
Sbjct: 1171 LPEANLLTFLFLLDHLKRVAEKEAVNKMSLHNLATVFGPTLLRPSEKESKLPANPSQPIT 1230
Query: 451 -----SIQVVGVVEALI 462
S++V+ V+ L+
Sbjct: 1231 MTDSWSLEVMSQVQVLL 1247
Score = 30.8 bits (68), Expect = 4.5
Identities = 29/99 (29%), Positives = 35/99 (35%), Gaps = 17/99 (17%)
Query: 508 ATTPAPAPAPAPAPAPALASAATKERTESEVPPRPASPKVTRSPPETAAPVEDMARRTKR 567
A+ P PAPA P PA A R + E P A P R P A+ D
Sbjct: 94 ASRPQPAPADGADPPPAEEPEA---RPDGEGSPGKARPGTARRPGAAASGERD------- 143
Query: 568 PAPARPTMPPPQVSGSRSSPPAPPLPPGSGSPGTPQALP 606
PP V+ RS+ + G G PG P
Sbjct: 144 -----DRGPPASVAALRSN--FERIRKGHGQPGADAEKP 175
>gi|4757980 beta chimerin isoform 2 [Homo sapiens]
Length = 468
Score = 102 bits (253), Expect = 2e-21
Identities = 61/201 (30%), Positives = 104/201 (51%), Gaps = 8/201 (3%)
Query: 272 RVYGVSLATHLQELGREIALPIEACVMMLLSEGMKEEGLFRLAAGASVLKRLKQTMASDP 331
+VY L T ++ + + ++ C+ + + G+K EGL+R++ ++ +K D
Sbjct: 273 KVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDG 332
Query: 332 HSLEEFCS---DPHAVAGALKSYLRELPEPLMTFDLYDDWMRAASLKEPGARLQALQEVC 388
+ + D + + GALK Y R+LP P++T+D Y ++ AA + RL+A+ EV
Sbjct: 333 EKADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVL 392
Query: 389 SRLPPENLSNLRYLMKFLARLAEEQEVNKMTPSNIAIVLGPNLLWPPEKEGDQAQLDAAS 448
LPP + LRYLM L ++ ++ N M N+ IV GP L+ PPE + L
Sbjct: 393 MLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPE----DSTLTTLH 448
Query: 449 VSSIQVVGVVEALIQSADTLF 469
Q + +V+ LI++ D LF
Sbjct: 449 DMRYQKL-IVQILIENEDVLF 468
>gi|91106928 beta chimerin isoform 1 [Homo sapiens]
Length = 332
Score = 102 bits (253), Expect = 2e-21
Identities = 61/201 (30%), Positives = 104/201 (51%), Gaps = 8/201 (3%)
Query: 272 RVYGVSLATHLQELGREIALPIEACVMMLLSEGMKEEGLFRLAAGASVLKRLKQTMASDP 331
+VY L T ++ + + ++ C+ + + G+K EGL+R++ ++ +K D
Sbjct: 137 KVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDG 196
Query: 332 HSLEEFCS---DPHAVAGALKSYLRELPEPLMTFDLYDDWMRAASLKEPGARLQALQEVC 388
+ + D + + GALK Y R+LP P++T+D Y ++ AA + RL+A+ EV
Sbjct: 197 EKADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVL 256
Query: 389 SRLPPENLSNLRYLMKFLARLAEEQEVNKMTPSNIAIVLGPNLLWPPEKEGDQAQLDAAS 448
LPP + LRYLM L ++ ++ N M N+ IV GP L+ PPE + L
Sbjct: 257 MLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPE----DSTLTTLH 312
Query: 449 VSSIQVVGVVEALIQSADTLF 469
Q + +V+ LI++ D LF
Sbjct: 313 DMRYQKL-IVQILIENEDVLF 332
>gi|4757766 Rho GTPase activating protein 1 [Homo sapiens]
Length = 439
Score = 101 bits (252), Expect = 2e-21
Identities = 63/164 (38%), Positives = 95/164 (57%), Gaps = 7/164 (4%)
Query: 274 YGVSLATHLQELGRE---IALPIEACVMMLLSEGMKEEGLFRLAAGASVLKRLKQTMASD 330
+GVSL HLQE E I + + V L + + EG+FR +A V++ ++Q
Sbjct: 242 FGVSLQ-HLQEKNPEQEPIPIVLRETVAYLQAHALTTEGIFRRSANTQVVREVQQKYNMG 300
Query: 331 -PHSLEEFCSDPHAVAGALKSYLRELPEPLMTFDLYDDWMRAASLKEPGARLQALQEVCS 389
P +++ ++ H A LK++LRELPEPL+TFDLY + ++ E R+ A +V
Sbjct: 301 LPVDFDQY-NELHLPAVILKTFLRELPEPLLTFDLYPHVVGFLNIDE-SQRVPATLQVLQ 358
Query: 390 RLPPENLSNLRYLMKFLARLAEEQEVNKMTPSNIAIVLGPNLLW 433
LP EN LR+L FL +++ + NKMT +N+A+V GPNLLW
Sbjct: 359 TLPEENYQVLRFLTAFLVQISAHSDQNKMTNTNLAVVFGPNLLW 402
>gi|71040096 Rho GTPase activating protein 30 isoform 2 [Homo
sapiens]
Length = 890
Score = 101 bits (252), Expect = 2e-21
Identities = 65/203 (32%), Positives = 102/203 (50%), Gaps = 4/203 (1%)
Query: 272 RVYGVSLATHLQELGREIALPIEACVMMLLSEGMKEEGLFRLAAGASVLKRLKQTMASDP 331
RV+G L HLQ G+E+ +++C + G+ + G++RL+ +S +++L+Q S+
Sbjct: 16 RVFGCDLQEHLQHSGQEVPQVLKSCAEFVEEYGVVD-GIYRLSGVSSNIQKLRQEFESER 74
Query: 332 HS---LEEFCSDPHAVAGALKSYLRELPEPLMTFDLYDDWMRAASLKEPGARLQALQEVC 388
+ + D H V+ K+Y RELP+PL+T+ LYD + A ++ RL + EV
Sbjct: 75 KPDLRRDVYLQDIHCVSSLCKAYFRELPDPLLTYRLYDKFAEAVGVQLEPERLVKILEVL 134
Query: 389 SRLPPENLSNLRYLMKFLARLAEEQEVNKMTPSNIAIVLGPNLLWPPEKEGDQAQLDAAS 448
LP N L +LM+ L +A M N+AIV PNLL + E AA
Sbjct: 135 RELPVPNYRTLEFLMRHLVHMASFSAQTNMHARNLAIVWAPNLLRSKDIEASGFNGTAAF 194
Query: 449 VSSIQVVGVVEALIQSADTLFPG 471
+ VVE ++ D LF G
Sbjct: 195 MEVRVQSIVVEFILTHVDQLFGG 217
Score = 35.0 bits (79), Expect = 0.24
Identities = 37/153 (24%), Positives = 53/153 (34%), Gaps = 14/153 (9%)
Query: 507 PATTPAPAPAPAPAPAPALASAATKERTESEVPPRPASPKVTRSPPETAAP--------- 557
PA P+PA P P P L E+ E+ PAS + S P+ AP
Sbjct: 450 PALQHRPSPASGPGPGPGLGPGPPDEKLEAS----PASSPLADSGPDDLAPALEDSLSQE 505
Query: 558 VEDMARRTKRPAPARPT-MPPPQVSGSRSSPPAPPLPPGSGSPGTPQALPRRLVGSSLRA 616
V+D + + + P + +++ PG PG VG +
Sbjct: 506 VQDSFSFLEDSSSSEPEWVGAEDGEVAQAEAAGAAFSPGEDDPGMGYLEELLGVGPQVEE 565
Query: 617 PTVPPPLPPTPPQPARRQSRRSPASPSPASPGP 649
+V PPL A+ S S A P P
Sbjct: 566 FSVEPPLDDLSLDEAQFVLAPSCCSLDSAGPRP 598
>gi|71040098 Rho GTPase activating protein 30 isoform 1 [Homo
sapiens]
Length = 1101
Score = 101 bits (252), Expect = 2e-21
Identities = 65/203 (32%), Positives = 102/203 (50%), Gaps = 4/203 (1%)
Query: 272 RVYGVSLATHLQELGREIALPIEACVMMLLSEGMKEEGLFRLAAGASVLKRLKQTMASDP 331
RV+G L HLQ G+E+ +++C + G+ + G++RL+ +S +++L+Q S+
Sbjct: 16 RVFGCDLQEHLQHSGQEVPQVLKSCAEFVEEYGVVD-GIYRLSGVSSNIQKLRQEFESER 74
Query: 332 HS---LEEFCSDPHAVAGALKSYLRELPEPLMTFDLYDDWMRAASLKEPGARLQALQEVC 388
+ + D H V+ K+Y RELP+PL+T+ LYD + A ++ RL + EV
Sbjct: 75 KPDLRRDVYLQDIHCVSSLCKAYFRELPDPLLTYRLYDKFAEAVGVQLEPERLVKILEVL 134
Query: 389 SRLPPENLSNLRYLMKFLARLAEEQEVNKMTPSNIAIVLGPNLLWPPEKEGDQAQLDAAS 448
LP N L +LM+ L +A M N+AIV PNLL + E AA
Sbjct: 135 RELPVPNYRTLEFLMRHLVHMASFSAQTNMHARNLAIVWAPNLLRSKDIEASGFNGTAAF 194
Query: 449 VSSIQVVGVVEALIQSADTLFPG 471
+ VVE ++ D LF G
Sbjct: 195 MEVRVQSIVVEFILTHVDQLFGG 217
Score = 35.0 bits (79), Expect = 0.24
Identities = 37/153 (24%), Positives = 53/153 (34%), Gaps = 14/153 (9%)
Query: 507 PATTPAPAPAPAPAPAPALASAATKERTESEVPPRPASPKVTRSPPETAAP--------- 557
PA P+PA P P P L E+ E+ PAS + S P+ AP
Sbjct: 450 PALQHRPSPASGPGPGPGLGPGPPDEKLEAS----PASSPLADSGPDDLAPALEDSLSQE 505
Query: 558 VEDMARRTKRPAPARPT-MPPPQVSGSRSSPPAPPLPPGSGSPGTPQALPRRLVGSSLRA 616
V+D + + + P + +++ PG PG VG +
Sbjct: 506 VQDSFSFLEDSSSSEPEWVGAEDGEVAQAEAAGAAFSPGEDDPGMGYLEELLGVGPQVEE 565
Query: 617 PTVPPPLPPTPPQPARRQSRRSPASPSPASPGP 649
+V PPL A+ S S A P P
Sbjct: 566 FSVEPPLDDLSLDEAQFVLAPSCCSLDSAGPRP 598
>gi|26986534 Rho GTPase activating protein 12 [Homo sapiens]
Length = 846
Score = 99.8 bits (247), Expect = 8e-21
Identities = 59/200 (29%), Positives = 110/200 (55%), Gaps = 9/200 (4%)
Query: 272 RVYGVSLATHLQELGREIALPIEACVMMLLSEGMKEEGLFRLAAGASVLKRLKQTMASDP 331
+V+G +LA Q + ++ C+ + G+ +G++R++ +V+++L+ + D
Sbjct: 652 QVFGSNLANLCQRENGTVPKFVKLCIEHVEEHGLDIDGIYRVSGNLAVIQKLRFAVNHDE 711
Query: 332 HS--LEEFCSDPHAVAGALKSYLRELPEPLMTFDLYDDWMRAASLKEPGARLQALQEVCS 389
+ D H + GALK + RELPEPL TF+ ++D++ A +EP R+ A++++
Sbjct: 712 KLDLNDSKWEDIHVITGALKMFFRELPEPLFTFNHFNDFVNAIK-QEPRQRVAAVKDLIR 770
Query: 390 RLPPENLSNLRYLMKFLARLAEEQEVNKMTPSNIAIVLGPNLLWPPEKEGDQAQLDAASV 449
+LP N ++ L + L R+ E E N+MT +IAIV GP LL P ++ G+ A V
Sbjct: 771 QLPKPNQDTMQILFRHLRRVIENGEKNRMTYQSIAIVFGPTLLKPEKETGNIA------V 824
Query: 450 SSIQVVGVVEALIQSADTLF 469
++ +VE ++ ++F
Sbjct: 825 HTVYQNQIVELILLELSSIF 844
>gi|194272142 myosin IXB isoform 2 [Homo sapiens]
Length = 2022
Score = 98.6 bits (244), Expect = 2e-20
Identities = 53/148 (35%), Positives = 87/148 (58%)
Query: 289 IALPIEACVMMLLSEGMKEEGLFRLAAGASVLKRLKQTMASDPHSLEEFCSDPHAVAGAL 348
+ + +E + + G+ EGL+R + A+ + L+Q + +DP +++ HA+ G L
Sbjct: 1712 VPIVLEKLLEHVEMHGLYTEGLYRKSGAANRTRELRQALQTDPAAVKLENFPIHAITGVL 1771
Query: 349 KSYLRELPEPLMTFDLYDDWMRAASLKEPGARLQALQEVCSRLPPENLSNLRYLMKFLAR 408
K +LRELPEPLMTF Y D++RA L E +L A+ V LP N ++L L+ L +
Sbjct: 1772 KQWLRELPEPLMTFAQYGDFLRAVELPEKQEQLAAIYAVLEHLPEANHNSLERLIFHLVK 1831
Query: 409 LAEEQEVNKMTPSNIAIVLGPNLLWPPE 436
+A ++VN+M+P +AI+ P LL P+
Sbjct: 1832 VALLEDVNRMSPGALAIIFAPCLLRCPD 1859
>gi|33356170 myosin IXB isoform 1 [Homo sapiens]
Length = 2157
Score = 98.6 bits (244), Expect = 2e-20
Identities = 53/148 (35%), Positives = 87/148 (58%)
Query: 289 IALPIEACVMMLLSEGMKEEGLFRLAAGASVLKRLKQTMASDPHSLEEFCSDPHAVAGAL 348
+ + +E + + G+ EGL+R + A+ + L+Q + +DP +++ HA+ G L
Sbjct: 1712 VPIVLEKLLEHVEMHGLYTEGLYRKSGAANRTRELRQALQTDPAAVKLENFPIHAITGVL 1771
Query: 349 KSYLRELPEPLMTFDLYDDWMRAASLKEPGARLQALQEVCSRLPPENLSNLRYLMKFLAR 408
K +LRELPEPLMTF Y D++RA L E +L A+ V LP N ++L L+ L +
Sbjct: 1772 KQWLRELPEPLMTFAQYGDFLRAVELPEKQEQLAAIYAVLEHLPEANHNSLERLIFHLVK 1831
Query: 409 LAEEQEVNKMTPSNIAIVLGPNLLWPPE 436
+A ++VN+M+P +AI+ P LL P+
Sbjct: 1832 VALLEDVNRMSPGALAIIFAPCLLRCPD 1859
Score = 38.9 bits (89), Expect = 0.016
Identities = 41/150 (27%), Positives = 53/150 (35%), Gaps = 34/150 (22%)
Query: 482 SAVTLQDTVSDRLASEELPSTAVPTP-ATTPAPAPAPAPAPAPALASAAT-KERTESEVP 539
S +L + + R ASE P+ A+P P A TP+P P A P +S T + +T P
Sbjct: 2004 STESLLEERAGRGASEGPPAPALPCPGAPTPSPLPTVAAPPRRRPSSFVTVRVKTPRRTP 2063
Query: 540 PRPAS------------PKVTRSPPETAAPVEDMARRTKRP------------------- 568
P + P+ E AAPV +RP
Sbjct: 2064 IMPTANIKLPPGLPSHLPRWAPGAREAAAPVRRREPPARRPDQIHSVYITPGADLPVQGA 2123
Query: 569 -APARPTMPPPQVSGSRSSPPAPPLPPGSG 597
P PP S PP LPP SG
Sbjct: 2124 LEPLEEDGQPPGAKRRYSDPPTYCLPPASG 2153
>gi|50843948 Rho GTPase activating protein 10 [Homo sapiens]
Length = 786
Score = 98.2 bits (243), Expect = 2e-20
Identities = 101/392 (25%), Positives = 166/392 (42%), Gaps = 69/392 (17%)
Query: 257 GQADHSPSMTATHFPRVYGVSLATHLQELGREIALPIEACVMMLLSEGMKEEGLFRLAAG 316
G+ S S PR G + L ++G I I C+ + + G+ ++GL+R+
Sbjct: 369 GKEALSHSFNTAIIPRPEGNA---QLDKMGFTI---IRKCISAVETRGINDQGLYRVVGV 422
Query: 317 ASVLKRLKQTMASDPHSLEEFCSDPHA------VAGALKSYLRELPEPLMTFDLYDDWMR 370
+S ++RL +M D + E + A + ALK YLR LPEPLMT++L+ D++
Sbjct: 423 SSKVQRLL-SMLMDVKTCNEVDLENSADWEVKTITSALKQYLRSLPEPLMTYELHGDFIV 481
Query: 371 AASLKEPGARLQALQEVCSRLPPENLSNLRYLMKFLARLAEEQEVNKMTPSNIAIVLGPN 430
A P +R+ A+ + +LP +N L L+K L ++ + N MT +N+ +V GP
Sbjct: 482 PAKSGSPESRVNAIHFLVHKLPEKNKEMLDILVKHLTNVSNHSKQNLMTVANLGVVFGPT 541
Query: 431 LLWPPEKEGDQAQLDAASVSSIQVVGVVEALIQSADTLF--PGDINFNVSGLFSA----- 483
L+ P E+ A L +I VVE LI++ + +F P D F SA
Sbjct: 542 LMRPQEE--TVAALMDLKFQNI----VVEILIENHEKIFRTPPDTTFPEPTCLSASPPNA 595
Query: 484 ----------------------VTLQDTVSDRLASEELPSTAV-----PTPATTPAPAPA 516
+ L+D + + E+ P++++ P+P TT P P
Sbjct: 596 PPRQSKRQGQRTKRPVAVYNLCLELEDGDNPYPSKEDTPTSSLDSLSSPSPVTTAVPGP- 654
Query: 517 PAPAPAPALASAATKERTESEVPPRPASPKVTRSPPETAAPVEDMARRTKRPAPARPTMP 576
P P LA + S +P + S V P++ T + P P
Sbjct: 655 PGPDKNHLLADGGSFGDWASTIPGQTRSSMVQWLNPQSPT-------TTSSNSAVTPLSP 707
Query: 577 PPQVSGSRSSPPAPPLPPGSGSPGTPQALPRR 608
S P P PP + + P+++ R
Sbjct: 708 --------GSSPFPFSPPATVADKPPESIRSR 731
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.128 0.364
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,266,618
Number of Sequences: 37866
Number of extensions: 2241507
Number of successful extensions: 65224
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1133
Number of HSP's successfully gapped in prelim test: 2683
Number of HSP's that attempted gapping in prelim test: 17495
Number of HSP's gapped (non-prelim): 21588
length of query: 701
length of database: 18,247,518
effective HSP length: 109
effective length of query: 592
effective length of database: 14,120,124
effective search space: 8359113408
effective search space used: 8359113408
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.