Guide to the Human Genome
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Search of human proteins with 84662781

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|84662781 DCP1 decapping enzyme homolog A [Homo sapiens]
         (582 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|84662781 DCP1 decapping enzyme homolog A [Homo sapiens]           1143   0.0  
gi|40548403 decapping enzyme Dcp1b [Homo sapiens]                     230   3e-60
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    68   2e-11
gi|163965366 nascent polypeptide-associated complex alpha subuni...    54   4e-07
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    49   1e-05
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    49   2e-05
gi|91982772 mucin 17 [Homo sapiens]                                    49   2e-05
gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]        48   2e-05
gi|146219843 Snf2-related CBP activator protein [Homo sapiens]         48   3e-05
gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [...    47   4e-05
gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]       47   6e-05
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    45   1e-04
gi|26051278 nuclear pore membrane protein 121 [Homo sapiens]           44   3e-04
gi|222418647 mucin 7, secreted precursor [Homo sapiens]                44   4e-04
gi|222418649 mucin 7, secreted precursor [Homo sapiens]                44   4e-04
gi|222418645 mucin 7, secreted precursor [Homo sapiens]                44   4e-04
gi|167736355 mucin 4 isoform a [Homo sapiens]                          44   5e-04
gi|194733742 Wolf-Hirschhorn syndrome candidate 2 protein [Homo ...    44   5e-04
gi|239751395 PREDICTED: hypothetical protein, partial [Homo sapi...    43   0.001
gi|239745904 PREDICTED: hypothetical protein, partial [Homo sapi...    43   0.001
gi|148612835 zinc finger protein 207 isoform c [Homo sapiens]          43   0.001
gi|4508017 zinc finger protein 207 isoform a [Homo sapiens]            43   0.001
gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]              42   0.001
gi|98986457 host cell factor 1 [Homo sapiens]                          42   0.001
gi|83367077 mucin 16 [Homo sapiens]                                    42   0.002
gi|116284392 mucin 2 precursor [Homo sapiens]                          42   0.002
gi|239743232 PREDICTED: hypothetical protein XP_002342775 [Homo ...    42   0.002
gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]       42   0.002
gi|222352122 hypothetical protein LOC284297 [Homo sapiens]             42   0.002
gi|150170670 piccolo isoform 2 [Homo sapiens]                          42   0.002

>gi|84662781 DCP1 decapping enzyme homolog A [Homo sapiens]
          Length = 582

 Score = 1143 bits (2956), Expect = 0.0
 Identities = 582/582 (100%), Positives = 582/582 (100%)

Query: 1   MEALSRAGQEMSLAALKQHDPYITSIADLTGQVALYTFCPKANQWEKTDIEGTLFVYRRS 60
           MEALSRAGQEMSLAALKQHDPYITSIADLTGQVALYTFCPKANQWEKTDIEGTLFVYRRS
Sbjct: 1   MEALSRAGQEMSLAALKQHDPYITSIADLTGQVALYTFCPKANQWEKTDIEGTLFVYRRS 60

Query: 61  ASPYHGFTIVNRLNMHNLVEPVNKDLEFQLHEPFLLYRNASLSIYSIWFYDKNDCHRIAK 120
           ASPYHGFTIVNRLNMHNLVEPVNKDLEFQLHEPFLLYRNASLSIYSIWFYDKNDCHRIAK
Sbjct: 61  ASPYHGFTIVNRLNMHNLVEPVNKDLEFQLHEPFLLYRNASLSIYSIWFYDKNDCHRIAK 120

Query: 121 LMADVVEEETRRSQQAARDKQSPSQANGCSDHRPIDILEMLSRAKDEYERNQMGDSNISS 180
           LMADVVEEETRRSQQAARDKQSPSQANGCSDHRPIDILEMLSRAKDEYERNQMGDSNISS
Sbjct: 121 LMADVVEEETRRSQQAARDKQSPSQANGCSDHRPIDILEMLSRAKDEYERNQMGDSNISS 180

Query: 181 PGLQPSTQLSNLGSTETLEEMPSGSQDKSAPSGHKHLTVEELFGTSLPKEQPAVVGLDSE 240
           PGLQPSTQLSNLGSTETLEEMPSGSQDKSAPSGHKHLTVEELFGTSLPKEQPAVVGLDSE
Sbjct: 181 PGLQPSTQLSNLGSTETLEEMPSGSQDKSAPSGHKHLTVEELFGTSLPKEQPAVVGLDSE 240

Query: 241 EMERLPGDASQKEPNSFLPFPFEQLGGAPQSETLGVPSAAHHSVQPEITTPVLITPASIT 300
           EMERLPGDASQKEPNSFLPFPFEQLGGAPQSETLGVPSAAHHSVQPEITTPVLITPASIT
Sbjct: 241 EMERLPGDASQKEPNSFLPFPFEQLGGAPQSETLGVPSAAHHSVQPEITTPVLITPASIT 300

Query: 301 QSNEKHAPTYTIPLSPVLSPTLPAEAPTAQVPPSLPRNSTMMQAVKTTPRQRSPLLNQPV 360
           QSNEKHAPTYTIPLSPVLSPTLPAEAPTAQVPPSLPRNSTMMQAVKTTPRQRSPLLNQPV
Sbjct: 301 QSNEKHAPTYTIPLSPVLSPTLPAEAPTAQVPPSLPRNSTMMQAVKTTPRQRSPLLNQPV 360

Query: 361 PELSHASLIANQSPFRAPLNVTNTAGTSLPSVDLLQKLRLTPQHDQIQTQPLGKGAMVAS 420
           PELSHASLIANQSPFRAPLNVTNTAGTSLPSVDLLQKLRLTPQHDQIQTQPLGKGAMVAS
Sbjct: 361 PELSHASLIANQSPFRAPLNVTNTAGTSLPSVDLLQKLRLTPQHDQIQTQPLGKGAMVAS 420

Query: 421 FSPAAGQLATPESFIEPPSKTAAARVAASASLSNMVLAPLQSMQQNQDPEVFVQPKVLSS 480
           FSPAAGQLATPESFIEPPSKTAAARVAASASLSNMVLAPLQSMQQNQDPEVFVQPKVLSS
Sbjct: 421 FSPAAGQLATPESFIEPPSKTAAARVAASASLSNMVLAPLQSMQQNQDPEVFVQPKVLSS 480

Query: 481 AIQVAGAPLVTATTTAVSSVLLAPSVFQQTVTRSSDLERKASSPSPLTIGTPESQRKPSI 540
           AIQVAGAPLVTATTTAVSSVLLAPSVFQQTVTRSSDLERKASSPSPLTIGTPESQRKPSI
Sbjct: 481 AIQVAGAPLVTATTTAVSSVLLAPSVFQQTVTRSSDLERKASSPSPLTIGTPESQRKPSI 540

Query: 541 ILSKSQLQDTLIHLIKNDSSFLSTLHEVYLQVLTKNKDNHNL 582
           ILSKSQLQDTLIHLIKNDSSFLSTLHEVYLQVLTKNKDNHNL
Sbjct: 541 ILSKSQLQDTLIHLIKNDSSFLSTLHEVYLQVLTKNKDNHNL 582


>gi|40548403 decapping enzyme Dcp1b [Homo sapiens]
          Length = 617

 Score =  230 bits (586), Expect = 3e-60
 Identities = 202/629 (32%), Positives = 288/629 (45%), Gaps = 92/629 (14%)

Query: 8   GQEMSLAALKQHDPYITSIADLTGQVALYTFCPKANQWEKTDIEGTLFVYRRSASPYHGF 67
           G+++SLAAL++HDPYI  I D+  QVALYTF  +AN+WEKTD+EGTLFVY RSASP HGF
Sbjct: 13  GRDISLAALQRHDPYINRIVDVASQVALYTFGHRANEWEKTDVEGTLFVYTRSASPKHGF 72

Query: 68  TIVNRLNMHNLVEPVNKDLEFQLHEPFLLYRNASLSIYSIWFYDKNDCHRIAKLMADVVE 127
           TI+NRL+M N  EP+ KDL+FQL +PFLLYRNA LSIY IWFYDK +C RIA+LM ++ +
Sbjct: 73  TIMNRLSMENRTEPITKDLDFQLQDPFLLYRNARLSIYGIWFYDKEECQRIAELMKNLTQ 132

Query: 128 EETRRSQQAARDKQSPSQANGCSDHRPIDILEMLSRAKDEYERNQMGDSNISSPG--LQP 185
            E  ++ Q      SP   N   + + +DIL ML +AKDEY + +      S P      
Sbjct: 133 YEQLKAHQGTGAGISPVILNS-GEGKEVDILRMLIKAKDEYTKCK----TCSEPKKITSS 187

Query: 186 STQLSNLGSTETLEEMPSGSQDKSAPSGH-------KHLTVEELFG----------TSLP 228
           S    N    + +   PS +Q +  P  +       +HL++  LFG             P
Sbjct: 188 SAIYDNPNLIKPIPVKPSENQQQRIPQPNQTLDPEPQHLSLTALFGKQDKATCQETVEPP 247

Query: 229 KEQPAVVGLDSEEMERLP------GDASQKEPNSFLPFPFEQLGGAPQSETLGVPSAAHH 282
           +          ++ E+LP         S +EP    P   +QL   P  + L V SA  H
Sbjct: 248 QTLHQQQQQQQQQQEKLPIRQGVVRSLSYEEPRRHSPPIEKQL--CPAIQKLMVRSADLH 305

Query: 283 SVQPEITTPVLITPASITQSNEKHAPTYTIPLSPVLSPTLPAEAPTAQVPPSLPRNSTMM 342
                   P+   P +    N            PV  P  P    T++   +  R   + 
Sbjct: 306 --------PLSELPENRPCENGSTHSAGEFFTGPV-QPGSPHNIGTSRGVQNASRTQNLF 356

Query: 343 QAVKTTPRQRSPLLNQPVPELSHASLIANQSPFRAPLNVTNTAGTSLPSVDLLQKLR--- 399
           + +++TP   +     P      +S   N+S  RAP +VT  A    P   L Q  +   
Sbjct: 357 EKLQSTPGAANKC--DPSTPAPASSAALNRS--RAPTSVTPVA----PGKGLAQPPQAYF 408

Query: 400 ---LTPQHDQIQTQPLGKGAMVASFSPAAG------------------QLATPESFIEPP 438
              L PQ    Q     +  +     P +G                  Q+   E  +   
Sbjct: 409 NGSLPPQTVGHQAHGREQSTLPRQTLPISGSQTGSSGVISPQELLKKLQIVQQEQQLHAS 468

Query: 439 SKTAAARVAASASLSNMVLAPLQSMQQNQDPEVFVQPKVLSSAIQVAGAPLVTATTTAVS 498
           ++ A A      + S+    PL+S   N+ P    Q    +   QV     + A  TA  
Sbjct: 469 NRPALAAKFPVLAQSSGTGKPLESW-INKTPNTEQQ----TPLFQVISPQRIPA--TAAP 521

Query: 499 SVLLAPSVFQQTVT-----RSSDLERKASSPSP-------LTIGTPESQRKPSIILSKSQ 546
           S+L++P VF Q  +     R S L        P       L I +PE     S  L+K Q
Sbjct: 522 SLLMSPMVFAQPTSVPPKERESGLLPVGGQEPPAAATSLLLPIQSPEPSVITSSPLTKLQ 581

Query: 547 LQDTLIHLIKNDSSFLSTLHEVYLQVLTK 575
           LQ+ L++LI+ND +FL+ ++E YL  +T+
Sbjct: 582 LQEALLYLIQNDDNFLNIIYEAYLFSMTQ 610


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 68.2 bits (165), Expect = 2e-11
 Identities = 93/390 (23%), Positives = 144/390 (36%), Gaps = 51/390 (13%)

Query: 185 PSTQLSNLGSTETLEEMPSGSQDKSAPSGHKHLTVEELFGTSLPKEQPAVVGLDSEEMER 244
           P   +S+     T E  P+  +  SA  G +      L  ++ P   PA  G  +    R
Sbjct: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPR 264

Query: 245 LPGDASQKEPNSFLPFPFEQLG----------GAPQSETLGVPSAAHHSVQP-----EIT 289
            P   SQ +P         Q+           G   S  L  PS +    +P        
Sbjct: 265 APAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAA 324

Query: 290 TPVLITPASITQSNEKHAPTYTIPLSPVLSPTL-----PAEAPTAQVPPSL-------PR 337
           TP+   PA++  S     P    P SP   P+L     P   P +Q PPS+       P 
Sbjct: 325 TPL---PATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPP 381

Query: 338 NSTMMQAVKTTPRQRSPLLNQPVPELSHASLIANQSPFRAPLNVTNTAGTSLP-----SV 392
           +   +  ++      SP L  P   L+ +SL A  S     L  T++  T  P     S+
Sbjct: 382 SLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASL 441

Query: 393 DLLQKLRLTPQHDQIQTQPLGKGA---MVASFSPAAGQLATPESFIEPPSKTAAARVAAS 449
               +   TP        PL   A   +  S SPA   L++P +     + ++ A  +  
Sbjct: 442 TSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQ 501

Query: 450 ASLSNMVLAPLQSMQQNQDPEVFVQPKVLS-----SAIQVAGAPLVTATTTAVSSVLLAP 504
           A LS++++ PL++      P +   P  L+     +   +A  PL TA     S+ L  P
Sbjct: 502 APLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTA-----SAPLTTP 556

Query: 505 SVFQQTVTRSSDLERKASSPSPLTIGTPES 534
            +          L+   + PSPLT   PE+
Sbjct: 557 HLETPPCPAPCPLQ---APPSPLTTPPPET 583



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 66/229 (28%), Positives = 81/229 (35%), Gaps = 41/229 (17%)

Query: 254 PNSFLPFPFEQLGGAPQSETLGVPSAAHHSVQPEITTPVLITPASITQSNEKHAPTYTIP 313
           P+  +  PF      P S +   PS A     P +  P L  P S         P  + P
Sbjct: 669 PSPPVQAPFSPPASPPVSPSATPPSQA----PPSLAAPPLQVPPS---------PPASPP 715

Query: 314 LSPVLSPTL----PAEAPTAQVPPSLPRNSTMMQAVKTTPRQRSPLLNQP---VPELSHA 366
           +SP  +P      P  AP  QVPPS P +  M  +  T P +  PLL  P   VP    A
Sbjct: 716 MSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSA-TPPPRVPPLLAAPPLQVPPSPPA 774

Query: 367 SLIANQSPFRAPLNVTNTAGTSLPSVDLLQKLRLTPQHDQIQTQPLGKGAMVASFSPAA- 425
           SL    SP   P      A  + P    LQ L   P     Q          A FSP+A 
Sbjct: 775 SL--PMSPLAKPPPQAPPALATPP----LQALPSPPASFPGQ----------APFSPSAS 818

Query: 426 ---GQLATPESFIEPPSKTAAARVAASASLSNMVLAPLQSMQQNQDPEV 471
                LATP     P       +V  S   S  + AP +      D  V
Sbjct: 819 LPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSV 867


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 70/277 (25%), Positives = 102/277 (36%), Gaps = 37/277 (13%)

Query: 185  PSTQLSNLGSTETLEEMPSGSQDKSAPSGHKHLTVEELFGTSLPKEQPAVVGLDSEEMER 244
            PS++   +  T TL      S+   A    K   +        PK+ PA+     +E   
Sbjct: 1520 PSSRRDPIAPTATLL-----SKKTPATLAPKEALIPPAMTVPSPKKTPAIP--TPKEAPA 1572

Query: 245  LPGDASQKEPNSFLPFPFEQLGGAPQSETLGVPSAAHHSVQPEITTPVLITPASITQSNE 304
             P       P +  P  ++   GAP  + L +P A       E  TP  +TP S  +   
Sbjct: 1573 TPSSKEASSPPAVTPSTYK---GAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPA 1629

Query: 305  KHAPTYTIPLSPVLSPTLPAEAPTAQVPPSLPRNSTMMQAVKTTPRQRSP-----LLNQP 359
              AP  T P SP ++P+   ++PT+    +    +T+ QA K  P ++ P     +L  P
Sbjct: 1630 TPAPKGT-PTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAP 1688

Query: 360  VPELSHASLIANQSPFRAPLNVTNTAGTSLP-------------SVDLLQKLRLTPQHDQ 406
             PE    S     +P R       ++ TS P              +  +    L P    
Sbjct: 1689 APE----STPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKD 1744

Query: 407  IQTQPLGKGAMVASFSPAAGQLATPESFIEPPSKTAA 443
                  GK    AS SP  G LA PES    P   AA
Sbjct: 1745 SSKTAKGKD---ASHSP-KGPLAPPESKASTPLTAAA 1777



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 78/326 (23%), Positives = 116/326 (35%), Gaps = 49/326 (15%)

Query: 254  PNSFLPFPFEQLGGAPQSETLGVPSAAHHSVQPEITTPVLITPASITQSN----EKHAPT 309
            PN  +  P    GG   S   G P            TP   TP S   S      K APT
Sbjct: 1287 PNPAVVTPPSPKGGPATSPPKGAP------------TPPAATPPSPKGSPGTPPPKGAPT 1334

Query: 310  --YTIPLSPVLSPTLPAEAPTAQVPPSLPRNSTMMQAVKTTPRQR-SPLLNQPVPELSHA 366
                 P SP  +PTLPA  P+++  P+ P +         TP  +  P +  P P+   A
Sbjct: 1335 PPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPA 1394

Query: 367  ----------SLIANQSPFRAPLNVTNTAGTSLPSVDLLQKLRLTP---QHDQIQTQPLG 413
                        +   SP +AP       G + PS   L    +TP   +     + P G
Sbjct: 1395 IPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKG 1454

Query: 414  KGAMVASFSPAAGQLATPESFIEPPS----KTAAARVAASASLSNMVLAPLQSMQQNQDP 469
              A  +S         TP S  EPP+     T+++   A A+ + M    L ++  +   
Sbjct: 1455 GPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPK 1514

Query: 470  EVFVQPKVLSSAIQVAGAPL--VTATTTAVSSVLLAPSVFQQTVTRSSDL---------- 517
            EV   P      I      L   T  T A    L+ P++   +  ++  +          
Sbjct: 1515 EVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATP 1574

Query: 518  -ERKASSPSPLTIGTPESQRKPSIIL 542
              ++ASSP  +T  T +    P  +L
Sbjct: 1575 SSKEASSPPAVTPSTYKGAPSPKELL 1600



 Score = 38.9 bits (89), Expect = 0.013
 Identities = 73/303 (24%), Positives = 120/303 (39%), Gaps = 39/303 (12%)

Query: 245 LPGDASQKEPNSFLPFPFEQLGGAPQSETLGVPSAAHHSVQPEITTPVLITPASITQSNE 304
           +PG+A++  P +    P       PQ+ET  +P ++  SV   +  P    P   + + +
Sbjct: 1   MPGEATETVPATEQELP------QPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQ 54

Query: 305 KHAPTYTIPLSPVLSPTLPAEAPTAQVPPSLPRNSTMMQAVKTTPRQRSPLLNQPVPELS 364
           +   +     SP  SP+  A  P  +VP     + T +  + T P   + L N   P +S
Sbjct: 55  QCPLSAANQASPFPSPSTIASTP-LEVPFPQSSSGTAL-PLGTAPEAPTFLPNLIGPPIS 112

Query: 365 HASLIANQSPFRAP-LNVTNTAGTSLPSVDL----LQKLRLTPQHDQIQTQP-------- 411
            A+L A  SP  AP L  T ++   L  V L    +QK    P +  + T P        
Sbjct: 113 PAAL-ALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPN--LLTSPPSVAVAES 169

Query: 412 ---LGKGAMVASFSPAAGQLATPESFIEPPSKTAAARVAASASLSNMVLAPLQSMQQNQD 468
              +   A +A   P       P   +  P  T +     S ++    + P+ S+Q    
Sbjct: 170 GSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVS-TVPYHCVTPMASIQSG-- 226

Query: 469 PEVFVQPKVLSSAIQVAGAPLVTATTTAVSSVLLAPSVFQQTVTRSSDLERKASSPSPLT 528
             V   P+   +      +P V  TT  +SSVL++P         S  L+   S P+ L+
Sbjct: 227 --VASLPQTTPTTTLAIASPQVKDTT--ISSVLISPQ-----NPGSLSLKGPVSPPAALS 277

Query: 529 IGT 531
           + T
Sbjct: 278 LST 280



 Score = 37.7 bits (86), Expect = 0.029
 Identities = 65/237 (27%), Positives = 95/237 (40%), Gaps = 43/237 (18%)

Query: 296 PASITQSNEKHAPTYTIPLSPVLSPTLPAEAPTAQVPPSLPRNSTMMQAVKTTPRQRSPL 355
           PA+  +  +  A T  +P+S  LS T     P   +PP  P +    Q   +   Q SP 
Sbjct: 10  PATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPP--PCSPAPQQCPLSAANQASPF 67

Query: 356 LNQPVPELSHASLIANQSPFRAPLNVTNTAGTSLPSVDLLQKLRLTPQHDQIQTQPLGKG 415
              P P     S IA+ +P   P    +++GT+LP       L   P+        +G  
Sbjct: 68  ---PSP-----STIAS-TPLEVPF-PQSSSGTALP-------LGTAPEAPTFLPNLIG-- 108

Query: 416 AMVASFSPAAGQLATPESFIEPPSKTAAARVAASASLSNMVLAPLQSMQQNQDPEVFVQP 475
                 SPAA  LA+P   I P   T     ++SA L+ + LAP    + +  P     P
Sbjct: 109 ---PPISPAALALASP--MIAP---TLKGTPSSSAPLALVALAPHSVQKSSAFP-----P 155

Query: 476 KVLSSAIQVAGAPLVTATTTAVSSVLLAPSVFQQTVTRSSDLERKASSPSPLTIGTP 532
            +L+S   VA A   +  T    S  +APS         ++L +  S   P   GTP
Sbjct: 156 NLLTSPPSVAVAESGSVITL---SAPIAPS------EPKTNLNKVPSEVVPNPKGTP 203



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 77/337 (22%), Positives = 126/337 (37%), Gaps = 72/337 (21%)

Query: 238 DSEEMERLPGDASQKEPNSFLPFPFEQLGGAPQSETLGVPSAAHHSVQPEITTPVLITPA 297
           D E+++ LP     K P        + L   P S    +  A     Q  +TT    T  
Sbjct: 511 DPEDLKNLPSSVLVKFPTQ------KDLQTVPAS----LEGAPFSPAQAGLTTKKDPTVL 560

Query: 298 SITQSNEKHAPTYT-------IPLSPV-------LSPTLPAEAPTAQVPPSLPRNSTMMQ 343
            + Q+  K++P++        IPLSP        L   LP   P + +   L  NS+   
Sbjct: 561 PLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSA-S 619

Query: 344 AVKTT----PRQRSPLLNQPV--PELSHASLIANQSPFRAPLNVTNTAG-TSLPSVDLLQ 396
            +KT     P    PLL   +  P ++   L +      AP     T+  T+  S  L  
Sbjct: 620 VIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEG 679

Query: 397 KLRLTPQHDQIQTQPLGKGAMVASFSPAAGQLATPESFIEPPSKTAAARVAASASLSNMV 456
            + L P++  ++   L    +V + S       +P++   P              L+ +V
Sbjct: 680 TVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAP--------------LATLV 725

Query: 457 LAPLQSMQQNQDPEVFVQPKVLSSAIQVAGAPLVT------ATTTAVSSVLLAP------ 504
           LAP             +   V S ++  AG P  T      + T+A++ V  +P      
Sbjct: 726 LAPE------------IPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTE 773

Query: 505 -SVFQQTVTRSSDLERKASSPSPLTIG-TPESQRKPS 539
            S    T +    L   A SPSPL +  +P+++R P+
Sbjct: 774 DSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPT 810


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
            sapiens]
          Length = 5537

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 77/335 (22%), Positives = 115/335 (34%), Gaps = 52/335 (15%)

Query: 228  PKEQPAVVGLDSEEMERLPGDASQKEPNSFL-PFPF-----------EQLG------GAP 269
            P  +P    LD+  +   PG    K     L P PF           E+LG      G P
Sbjct: 2243 PFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPP 2302

Query: 270  QSETLGVPSAAHHSVQPEITTPVLITPASITQSNEKHAPTYTIPLSPVLSPTLPAEAPTA 329
                +  PS+  H    E+ TP +       ++++    +  + L P   P   A AP+ 
Sbjct: 2303 NLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPS- 2361

Query: 330  QVPPSLPRNSTMMQAVKTTPRQRSPLLNQPVPELSHASLIANQSPFRAPLNVTNTAGTSL 389
              PPS P          T P  + PL  +P P                P +       SL
Sbjct: 2362 --PPSHP--DIFRPGSYTDPYAQPPLTPRPQPP--------------PPESCCALPPRSL 2403

Query: 390  PSVDLLQKLRLTPQHDQIQTQPLGKGAMVASF---SPAAGQLATPESFIEPPSKTAAARV 446
            PS D   ++  +PQ       PL    + A     SP   +  +P+ +  PPS+      
Sbjct: 2404 PS-DPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQ---- 2458

Query: 447  AASASLSNMVLAPLQSMQQNQDPEV-FVQPKVLSSAIQVAGAPLVTATTTAVSSVLLAPS 505
                  S    APL    + Q PEV F    +  +++   G P       A       PS
Sbjct: 2459 ------SRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPS 2512

Query: 506  VFQQTVTRSSDLERKASSPSPLTIGTPESQRKPSI 540
                   RS        +PSP+    P++  +PS+
Sbjct: 2513 GQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSL 2547



 Score = 35.4 bits (80), Expect = 0.15
 Identities = 41/168 (24%), Positives = 70/168 (41%), Gaps = 10/168 (5%)

Query: 305 KHAPTYTIPLSPVLSPTLPAEAPTAQVPPSLPRNSTMMQAVKTTPRQRSPLLNQPVPELS 364
           + +PT   P +  LSP  P E P + +P +L  +  + ++  + P + SPL   P PE S
Sbjct: 454 EESPTSPPPEASRLSPP-PEELPASPLPEALHLSRPLEESPLSPPPEESPL--SPPPESS 510

Query: 365 HASLIANQSPFRAPLNVTNTAGTSLPSVDLLQKLRLTPQHDQIQTQPLGKGAMVASFSPA 424
             S +  +SP   P     +     P     +   L+P  ++    P  +  +  S  P 
Sbjct: 511 PFSPL-EESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPE-ELPTSPPPE 568

Query: 425 AGQLATP--ESFIEPPSKTAAARVAASASLSNMVLAPLQSMQQNQDPE 470
           A +L+ P  ES + PP + +       AS    +  P +    +  PE
Sbjct: 569 ASRLSPPPEESPMSPPPEESPMSPPPEAS---RLFPPFEESPLSPPPE 613



 Score = 33.5 bits (75), Expect = 0.55
 Identities = 58/225 (25%), Positives = 87/225 (38%), Gaps = 35/225 (15%)

Query: 199 EEMPSGSQDKSAPSGHKHLTVEELFGTSLPKEQPAVVGLDSEEMERLPGDASQKEPNSFL 258
           EE P     +S+P      +  E    S P+E P    L++      P +AS   P    
Sbjct: 499 EESPLSPPPESSP-----FSPLEESPLSPPEESPPSPALETPLSP--PPEASPLSP---- 547

Query: 259 PFPFEQLGGAPQSETLGV---PSAAHHSVQPEITTPVLITPASITQSNEKHAPTYTIPL- 314
             PFE+   +P  E L     P A+  S  PE  +P+   P     S    A     P  
Sbjct: 548 --PFEESPLSPPPEELPTSPPPEASRLSPPPE-ESPMSPPPEESPMSPPPEASRLFPPFE 604

Query: 315 -SPVLSPTLPAEAPTAQVPPSL-----PRNSTMMQAVKTTPRQRSPLLNQ--PVPELSHA 366
            SP+  P  P E+P +  P +      P +S M    + +P    P +++  P+P +S  
Sbjct: 605 ESPLSPP--PEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRL 662

Query: 367 SLIANQSPFRAPLNVTNTAGTSLPSVDLLQKLRLTPQHDQIQTQP 411
           S    +SP   P      + TS P     +  RL+P  +   T P
Sbjct: 663 SPPPEESPLSPP---PEESPTSPPP----EASRLSPPPEDSPTSP 700



 Score = 32.3 bits (72), Expect = 1.2
 Identities = 34/136 (25%), Positives = 57/136 (41%), Gaps = 18/136 (13%)

Query: 228 PKEQPAVVGLDSEEMERLPGDASQKEPNSFLPFPFEQLGGAPQSETLG-VPSAAHHSVQP 286
           P+E P     ++  +   P D+    P    P     +   P+   L  +P  +  S  P
Sbjct: 612 PEESPLSPPPEASRLSPPPEDSPMSPPPEESP-----MSPPPEVSRLSPLPVVSRLSPPP 666

Query: 287 EITTPVLITPASITQSNEKHAPTYTIPLSPVLSPTLPAEAPTAQVPPSLPRNSTMMQAVK 346
           E  +P+   P        + +PT   P +  LSP  P ++PT+  P   P +     ++ 
Sbjct: 667 E-ESPLSPPP--------EESPTSPPPEASRLSPP-PEDSPTSPPPEDSPASPPPEDSLM 716

Query: 347 TTPRQRSPLLNQPVPE 362
           + P + SPLL  P+PE
Sbjct: 717 SLPLEESPLL--PLPE 730



 Score = 30.8 bits (68), Expect = 3.6
 Identities = 38/156 (24%), Positives = 56/156 (35%), Gaps = 20/156 (12%)

Query: 291  PVLITPASITQSNEKHAPTYTIPLSPV------LSPTLPAEAPTAQVPPSLPRNSTMMQA 344
            P    PAS    +   +P    PLS        ++P   +  P ++ PPS P++      
Sbjct: 2407 PFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSR-PPSRPQSRDPFAP 2465

Query: 345  VKTTPRQRSPLLNQPVPELSHASLIANQSPFRAPLNVTNTAGTSLPSVDLLQKLRLTPQH 404
            +   PR + P +      L+H SL A   P   P          +PS           Q 
Sbjct: 2466 LHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPS----------GQP 2515

Query: 405  DQIQTQPLGKGAMVASFSPAAGQLATPESFIEPPSK 440
                  P G GA V + SP   +   P++  EP  K
Sbjct: 2516 PNFVRSP-GTGAFVGTPSPM--RFTFPQAVGEPSLK 2548



 Score = 30.8 bits (68), Expect = 3.6
 Identities = 39/161 (24%), Positives = 56/161 (34%), Gaps = 31/161 (19%)

Query: 307  APTYTIPLSPVLSPTLPAEAPTAQVPP-----------SLPRNSTMMQAVKTTPRQRSPL 355
            AP   +   PVL P  P   P++   P            LP  + +      TP+ + P 
Sbjct: 4291 APPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPT 4350

Query: 356  LNQPVPELSHASLIANQSPFRAPLN----VTNTAGTSLPSVDLLQKLRLTPQH-DQIQTQ 410
            L  P   +S A+     + F   L       N A T  P     ++  L P H DQ+  Q
Sbjct: 4351 LEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKP-----EQSSLVPGHLDQVNGQ 4405

Query: 411  PLGKGAMVASFSPAAGQLATPESFIEPPSKTAAARVAASAS 451
             +          P A QL+  +   E P    A  V   A+
Sbjct: 4406 VV----------PEASQLSIKQEPREEPCALGAQSVKREAN 4436


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 77/301 (25%), Positives = 111/301 (36%), Gaps = 32/301 (10%)

Query: 185 PSTQLSNLGSTETLEEMPSGSQDKSAPSGHKHLTVEELFGTSLPKEQPAVVGLDSEEMER 244
           P   +S+     T E  P+  +  SA  G +      L  ++ P   PA  G  +    R
Sbjct: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPR 264

Query: 245 LPGDASQKEPNSFLPFPFEQLGGAPQSETLGVPSAAHHSVQPEITTPVLITPASITQSNE 304
            P   SQ +P         Q+   P+ +    P+    S  P + TP   +P++  QS  
Sbjct: 265 APAHPSQPKPKGLQALRPPQV-TPPRKD--AAPALGPLSSSP-LATP---SPSAALQS-- 315

Query: 305 KHAPTYTIPLSP-------VLSPTLPAEAPTAQVPPSLPRNSTMMQAVKTTPRQRSPLLN 357
             AP  T+P +P        L+  LP   P+   PPSL    T+     T P Q +  L 
Sbjct: 316 -QAPP-TLPATPHSSSLTCQLATPLPLAPPSPSAPPSL---QTLPSPPATPPSQATTSLG 370

Query: 358 QPVPELSHASLIANQSPFRAPLNVTNTAGTSLPSVDLLQKLRLTPQHD-QIQTQPLGKGA 416
            P  + +H+ L    SP   PL+   T     P    L  L+  P         PL   +
Sbjct: 371 SPTLQATHSFL---PSP---PLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPS 424

Query: 417 MVASFSPAAGQLATPESFIEPPSKTAAARVA--ASASLSNMVLAPLQSMQQNQDPEVFVQ 474
             A  + A   L  P  F  PPS    A  +  AS  +S     P Q+      P + V 
Sbjct: 425 PQAPNALAVHLLQAP--FSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVP 482

Query: 475 P 475
           P
Sbjct: 483 P 483



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 78/349 (22%), Positives = 124/349 (35%), Gaps = 36/349 (10%)

Query: 202 PSGSQDKSAPSGHKHLTVEELFGTSLPKEQPAVVGLDSEEMERLPGDASQKEPNSFLPFP 261
           P+    KS  S  +H T E    +   + +P+  G        L   AS+   +S  P  
Sbjct: 201 PTEGPRKSVSSASEHSTTEP---SPAARRRPSAGG-------GLQRPASRSLSSSATPLS 250

Query: 262 FEQLGGAPQSETLGVPSAAHHSVQPEITTPVLITPASITQSNEKHAPTY-TIPLSPVLSP 320
                G       G P A  H  QP+      + P  +T   +  AP    +  SP+ +P
Sbjct: 251 SPARSGP---SARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATP 307

Query: 321 TLPAEAPTAQVPPSLPR--NSTMMQAVKTTPRQRSPLLNQPVPELSHASLIANQSPFRAP 378
           + P+ A  +Q PP+LP   +S+ +     TP   +P    P P    +       P   P
Sbjct: 308 S-PSAALQSQAPPTLPATPHSSSLTCQLATPLPLAP----PSPSAPPSLQTLPSPPATPP 362

Query: 379 LNVTNTAGTSLPSVDLLQKLRLTPQHDQIQTQP------LGKGAMVASFSPAAGQLATPE 432
              T + G+  P++        +P    + T P      L    + A  SP A    +P 
Sbjct: 363 SQATTSLGS--PTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPL 420

Query: 433 SFIEPPSKTAAARVAASASLSNMVLAPLQS-MQQNQDPEVFVQPKVLSSAIQVAGAPLVT 491
           +   P +  A A     A  S     P+Q+       P V       S A     AP + 
Sbjct: 421 ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQ 480

Query: 492 ATTTAVSSVLLAPSVFQQTVTRSSDLERKASSPSPLTIGTPESQRKPSI 540
              +  +S  ++PS      T         ++P PL +  P  Q  P++
Sbjct: 481 VPPSPPASPPMSPS-----ATPPPQAPPPLAAP-PLQLAKPPPQAPPAL 523



 Score = 32.0 bits (71), Expect = 1.6
 Identities = 53/206 (25%), Positives = 67/206 (32%), Gaps = 40/206 (19%)

Query: 254 PNSFLPFPFEQLGGAPQSETLGVPSAAHHSVQPEITTPVLITPASITQSNEKHAPTYTIP 313
           P+  +  PF      P S +   PS A     P +  P L  P S         P  + P
Sbjct: 444 PSPPVQAPFSPPASPPVSPSATPPSQA----PPSLAAPPLQVPPS---------PPASPP 490

Query: 314 LSPVLSPTLPAEAPTAQVPPSLPRNSTMMQAVKTTPRQRSPLLNQPVPELSHASLIANQS 373
           +SP  +P   A  P A  P  L +          TP    PL   P P  S       Q+
Sbjct: 491 MSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATP----PLQALPSPPAS----FPGQA 542

Query: 374 PFRAPLNVTNTAGTSLPSVDLLQKLRLTPQHDQIQTQPLGKGAMVASFSPAAGQLATPES 433
           PF        +   SLP   L       PQ   +   PL     V    PA+  L  P  
Sbjct: 543 PF--------SPSASLPMSPLATP---PPQAPPVLAAPL---LQVPPSPPASPTLQAPR- 587

Query: 434 FIEPPSKTAAARVAASASLSNMVLAP 459
              PP  T     + S     + LAP
Sbjct: 588 --RPP--TPGPDTSVSGPRLTLALAP 609


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 71/319 (22%), Positives = 118/319 (36%), Gaps = 19/319 (5%)

Query: 225  TSLPKEQPAVVGLDSEEMERLPGDASQKEPNSFLPFPFEQLGGAPQSETLGVP-SAAHHS 283
            TS+      V   ++  + R P D S     S      E       +E  G+P S     
Sbjct: 2990 TSMSVSTMPVASSEASTLSRTPADTSTPVTTST-----EASSSPTTAEGTGIPISTPSEG 3044

Query: 284  VQPEITTPVLITPASITQSNEKHAPTYTIPLSPVLSPTLPAEAPTAQVPPSLPRNSTMMQ 343
              P  + PV  TP +I +++   + T     SPV++ T  + +PT     S+P ++    
Sbjct: 3045 STPLTSIPVSTTPVAIPEASTL-STTPVDSNSPVVTSTEVSSSPTPAEGTSMPIST---Y 3100

Query: 344  AVKTTPRQRSPLLNQPVPELSHASLIANQSPFRAPLNVTNTAGTSLPSVDLLQKLRLTPQ 403
            +  +TP    P+   PV   + ++L         P+  +  A +S  + +       TP 
Sbjct: 3101 SEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPS 3160

Query: 404  HDQIQTQPLGKGAMVASFSPAAGQLATP-------ESFIEPPSKTAAARVAASASLSNMV 456
                    +    M+   S  +   ATP        +  E  S T A   +   S  +  
Sbjct: 3161 EGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEG 3220

Query: 457  LAPLQSMQQNQDPEVFVQPKVLSSAIQVAGAPLVTATTTAVSSVLLAPSVFQQTVTRSSD 516
            + PL S+  +  P    +  +LS+    +  PL T+T  A SS   A      T T S  
Sbjct: 3221 MTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTST-EASSSPPTAEGTSMPTSTPSEG 3279

Query: 517  LERKASSP-SPLTIGTPES 534
                 S P S  T+ + E+
Sbjct: 3280 STPLTSMPVSTTTVASSET 3298



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 85/371 (22%), Positives = 131/371 (35%), Gaps = 29/371 (7%)

Query: 176  SNISSPGLQPSTQLSNLGSTETLEEMPSGSQDKSAPSGHKHLTVEELFGTSLPKEQPAVV 235
            S +S+  +  ST ++N  STE     P+ S+  S P+            TS+P     VV
Sbjct: 2179 STLSTTPVDTSTPVTN--STEA-RSSPTTSEGTSMPTSTPSEGSTPF--TSMPVSTMPVV 2233

Query: 236  GLDSEEMERLPGDASQKEPNSFLPFPFEQLGGAPQSETLGVPSAAHHSVQPEITTPVLIT 295
              ++  +   P D S     S      E       +E   +P+    S   E TTP+   
Sbjct: 2234 TSEASTLSATPVDTSTPVTTST-----EATSSPTTAEGTSIPT----STLSEGTTPLTSI 2284

Query: 296  PASITQSNEKHAPTYTIPLSPVLSPTLPAEAPTAQVPPSLPRNSTMMQAVKT---TPRQR 352
            P S T     ++   T+  +PV S T    +  A  PP     ++M  +  +   TP  R
Sbjct: 2285 PVSHTLV--ANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTR 2342

Query: 353  SPLLNQPVPELSHASLIANQSPFRAPLNVTNTAGTSLPSVDLLQKLRLTPQHDQIQTQPL 412
             P+    V     ++L    +    P+   + AG+S  + D       T          +
Sbjct: 2343 MPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSV 2402

Query: 413  GKGAMVASFSPAAGQLATPESFIEP--------PSKTAAARVAASASLSNMVLAPLQSMQ 464
                M    S A+    TP     P         S T A   +   S  +    PL SM 
Sbjct: 2403 PVSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMP 2462

Query: 465  QNQDPEVFVQPKVLSSAIQVAGAPLVTATTTAVSSVLLAPSVFQQTVTRSSDLERKASSP 524
             +  P V  +   LS+       P+ T +T A SS   A  +     T S       S P
Sbjct: 2463 VSTTPVVSSEAGTLSTTPVDTSTPM-TTSTEASSSPTTAEDIVVPISTASEGSTLLTSIP 2521

Query: 525  -SPLTIGTPES 534
             S   + +PE+
Sbjct: 2522 VSTTPVASPEA 2532



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 60/286 (20%), Positives = 106/286 (37%), Gaps = 24/286 (8%)

Query: 225  TSLPKEQPAVVGLDSEEMERLPGDASQKEPNSFLPFPFEQLGGAPQS-ETLGVPSAAHHS 283
            T +P     V   ++  +   P D S           + Q G +P + +   +P++ +  
Sbjct: 2341 TRMPVSTTMVASFETSTLSTTPADTSTPVTT------YSQAGSSPTTADDTSMPTSTYSE 2394

Query: 284  VQPEITTPVLITPASITQSNEKHAPTYTIPLSPVLSPTLPAEAPTAQVPPSLPRNSTMMQ 343
                +T+  + T   ++     H+ T     +PV + T  + +PT     S+P   T   
Sbjct: 2395 GSTPLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIP---TSPP 2451

Query: 344  AVKTTPRQRSPLLNQPVPELSHASLIANQSPFRAPLNVTNTAGTSLPSV--DLLQKLRLT 401
            +  TTP    P+   PV      +L         P+  T+T  +S P+   D++  +   
Sbjct: 2452 SEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTSTPM-TTSTEASSSPTTAEDIVVPISTA 2510

Query: 402  PQHDQIQTQPLGKGAMVASFSPAAGQLATPESFIEPP---------SKTAAARVAASASL 452
             +   + T        VA  SP A  L+T       P         S T+A   +   S 
Sbjct: 2511 SEGSTLLTSIPVSTTPVA--SPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTST 2568

Query: 453  SNMVLAPLQSMQQNQDPEVFVQPKVLSSAIQVAGAPLVTATTTAVS 498
             +    PL+SM  +  P    +   LS+       P+ T+T T+ S
Sbjct: 2569 YSEGSTPLRSMPVSTKPLASSEASTLSTTPVDTSIPVTTSTETSSS 2614



 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 80/389 (20%), Positives = 149/389 (38%), Gaps = 36/389 (9%)

Query: 186 STQLSNLGSTETLEEMP--SGSQDKSAPSGHKHLTVEELFGTSLPKEQ--PAVVGLDSEE 241
           S++ S L +T     +P  + ++  S+P+     T E   GTS+P          L S  
Sbjct: 289 SSEASTLSTTPAATNIPVITSTEASSSPT-----TAE---GTSIPTSTYTEGSTPLTSTP 340

Query: 242 MERLPGDASQKEPNSFLPFPFEQLGGAPQSETLGVPSAAHH-----SVQPEITTPVLITP 296
              +P   S+    S  P     L     +E   +P+ A       S   E +TP+   P
Sbjct: 341 ASTMPVATSEMSTLSITPVDTSTLV-TTSTEPSSLPTTAEATSMLTSTLSEGSTPLTNMP 399

Query: 297 AS-ITQSNEKHAPTYTIPLSPVLSPTLPAEAPTAQVPPSLPRNSTMMQAVKTTPRQRSPL 355
            S I  ++ + + T TIP+      T  +EA ++         +T   +  +TP    P+
Sbjct: 400 VSTILVASSEASTTSTIPVDSKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPV 459

Query: 356 LNQPVPELSHASLIANQSPFRAPLNVTNTAGTSLPSVDLLQKLRLTPQHDQIQTQPLGKG 415
              PV     ++L       +  +  +  A +S P+ ++      TP         +   
Sbjct: 460 STTPVASSEASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVS 519

Query: 416 AMVASFSPAAGQLATPESFIEPPSKTAAARVAASASLSNMVLAPLQSMQQNQDPEVFVQP 475
            M  + S A+    TP     P   T ++  ++S++       P  +  +   P   +  
Sbjct: 520 TMPVASSEASTLSTTPVDTSTP--VTTSSEASSSSTTPEGTSIPTSTPSEGSTP---LTN 574

Query: 476 KVLSSAIQVAGAPLVTATTTAVSSVLLAPSVFQQTVTRSSDLERKASSPSPLTIGTPESQ 535
             +S+ + V+     T+TT A S+           VT SS+    +++    ++ T    
Sbjct: 575 MPVSTRLVVSSEASTTSTTPADSNTF---------VTTSSEASSSSTTAEGTSMPTSTYS 625

Query: 536 RKPSIILSKSQLQDTLIHLIKNDSSFLST 564
            + + I S S +  TL+    +++S LST
Sbjct: 626 ERGTTITSMS-VSTTLV--ASSEASTLST 651



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 88/441 (19%), Positives = 160/441 (36%), Gaps = 62/441 (14%)

Query: 124 DVVEEETRRSQQAARDKQSPSQANGCSDHRPIDILEMLSRAKDEYERNQMGDSNISSPGL 183
           DV+  + ++  Q  R   + + A G +    ++    LS + +    +        +PG+
Sbjct: 46  DVLNRQCQQLSQHVRTGSAANTATGTTSTNVVEPRMYLSCSTNPEMTSIESSVTSDTPGV 105

Query: 184 QPSTQLSNLGSTETLEE-------MPSGSQDKSAPSGHKHLTVEELFGTSLPKEQPAVVG 236
             ST+++   S  T E         PS ++D S+P+  +        GT +P   P+   
Sbjct: 106 S-STRMTPTESRTTSESTSDSTTLFPSSTEDTSSPTTPE--------GTDVPMSTPSEES 156

Query: 237 LDSEEMERLPGDASQKEPNSFLPF------PFEQLGGAPQSETLGVPSAAHHSVQPEITT 290
           + S             E  + L +      P      A  S T    +    S   E +T
Sbjct: 157 ISSTMAFVSTAPLPSFEAYTSLTYKVDMSTPLTTSTQASSSPTTPESTTIPKSTNSEGST 216

Query: 291 PVLITPASITQSNEKHAPTY-TIPLSPVLSPTLPAEAPTAQVPPSLPRNSTMMQAVKTTP 349
           P+   PAS  +     A T  T P+      T+ A+A ++      P  S    +  +TP
Sbjct: 217 PLTSMPASTMKVASSEAITLLTTPVEISTPVTISAQASSSPTTAEGPSLSNSAPSGGSTP 276

Query: 350 RQRSPLLNQPVPELSHASLIANQSPFRAPLNVTNTAGTSLPSVDLLQKLRLTPQHDQIQT 409
             R PL    V     ++L    +    P+ +T+T  +S P+         T +   I T
Sbjct: 277 LTRMPLSVMLVVSSEASTLSTTPAATNIPV-ITSTEASSSPT---------TAEGTSIPT 326

Query: 410 QPLGKGAMVASFSPAAGQLATPESFIEPPSKTAAARVAASASLSNMVLAPLQ-------S 462
               +G+   + +P                  A+    A++ +S + + P+        S
Sbjct: 327 STYTEGSTPLTSTP------------------ASTMPVATSEMSTLSITPVDTSTLVTTS 368

Query: 463 MQQNQDPEVFVQPKVLSSAIQVAGAPLVTATTTAVSSVLLAPSVFQQTVTRSSDLERKAS 522
            + +  P       +L+S +     PL   T   VS++L+A S    T T   D +   +
Sbjct: 369 TEPSSLPTTAEATSMLTSTLSEGSTPL---TNMPVSTILVASSEASTTSTIPVDSKTFVT 425

Query: 523 SPSPLTIGTPESQRKPSIILS 543
           + S  +  +P +    SI  S
Sbjct: 426 TASEAS-SSPTTAEDTSIATS 445



 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 81/325 (24%), Positives = 115/325 (35%), Gaps = 41/325 (12%)

Query: 225 TSLPKEQPAVVGLDSEEMERLPGDASQKEPNSFLPFPFEQLGGAPQSETLGVPSAAHHSV 284
           TS+P     V   ++  +   P D S          P      A  S T    ++   S 
Sbjct: 691 TSMPVNTTLVASSEASTLSTTPVDTST---------PVTTSTEASSSPTTADGASMPTST 741

Query: 285 QPEITTPVLITPASITQSNEKHAPTY-TIPLSPVLSPTLPAEA---PTAQVPPSLPRNST 340
             E +TP+   P S T      A T  T PL      T   EA   PT     S+P +  
Sbjct: 742 PSEGSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPIS-- 799

Query: 341 MMQAVKTTPRQRSPLLNQ------PV--PELSHASL--IANQSPFRAPLNVTNTA----G 386
                  TP + SPLL        PV  PE S  S   + + SP      V+++     G
Sbjct: 800 -------TPSEGSPLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEG 852

Query: 387 TSLPSVDLLQKLRLTPQHDQIQTQPLGKGAMVASFSPAAGQLATP--ESFIEPPSKTAAA 444
           TS+P+    +    TP      +  L   + +++ S      +TP   S     S T + 
Sbjct: 853 TSMPTSTYSEGR--TPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSE 910

Query: 445 RVAASASLSNMVLAPLQSMQQNQDPEVFVQPKVLSSAIQVAGAPLVTATTTAVSSVLLAP 504
             +   S       PL SM  +  P V  + + LS+       P VT +T A SS   A 
Sbjct: 911 GTSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTP-VTTSTEATSSPTTAE 969

Query: 505 SVFQQTVTRSSDLERKASSPSPLTI 529
                T T S       S+P   T+
Sbjct: 970 GTSIPTSTPSEGTTPLTSTPVSHTL 994



 Score = 38.1 bits (87), Expect = 0.022
 Identities = 71/330 (21%), Positives = 121/330 (36%), Gaps = 31/330 (9%)

Query: 225 TSLPKEQPAVVGLDSEEMERLPGD----------ASQKEPNS---FLPFPFEQLGGAP-Q 270
           TS+P     V   ++  +   P D          AS   P +    +P      G  P  
Sbjct: 455 TSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLT 514

Query: 271 SETLGVPSAAHHSVQPEITTPVLITPASITQSNEKHAPTYTIPLSPVLSPTLPAEA--PT 328
           S ++     A        TTPV  T   +T S+E  + + T P    +  + P+E   P 
Sbjct: 515 SMSVSTMPVASSEASTLSTTPV-DTSTPVTTSSEASSSS-TTPEGTSIPTSTPSEGSTPL 572

Query: 329 AQVPPSLPRN-STMMQAVKTTPRQRSPLLNQPVPELSHASLIANQSPFRAPLNVTNTAGT 387
             +P S     S+      TTP   +  +     E S +S  A  +    P +  +  GT
Sbjct: 573 TNMPVSTRLVVSSEASTTSTTPADSNTFVTTS-SEASSSSTTAEGTSM--PTSTYSERGT 629

Query: 388 SLPSVDLLQKLRLTPQHDQIQTQPLGKGAMVASFSPAAGQLATPESFIEPPSK-TAAARV 446
           ++ S+ +   L  + +   + T P+     V + + A     T E    P S  T  +  
Sbjct: 630 TITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTP 689

Query: 447 AASASLSNMVLAPLQSMQQNQDP-----EVFVQPKVLSSAIQVAGAPLVTATTTAVSSVL 501
             S  ++  ++A  ++   +  P      V    +  SS     GA + T+T +  S+ L
Sbjct: 690 LTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPL 749

Query: 502 LAPSVFQQTVTRSSDLERKASSPSPLTIGT 531
            +  V +  +T S   E    S +PL   T
Sbjct: 750 TSMPVSKTLLTSS---EASTLSTTPLDTST 776



 Score = 38.1 bits (87), Expect = 0.022
 Identities = 74/336 (22%), Positives = 121/336 (36%), Gaps = 57/336 (16%)

Query: 186  STQLSNLGSTETLEEMPSGSQ-DKSAPSGHKHLTVEELFGTSLPKEQPAVVGLDSEEMER 244
            ST+ S+   T  +  MP+ +  ++S P             TS+P     V   ++  +  
Sbjct: 1194 STEASSPPPTAEVTSMPTSTPGERSTPL------------TSMPVRHTPVASSEASTLST 1241

Query: 245  LPGDASQKEPNSFLPFPFEQLGGAPQSETLGVPSAAHHSVQPEITTP---VLIT--PASI 299
             P D S     S              +ET   P+ A  +  P  TT     L+T  P S 
Sbjct: 1242 SPVDTSTPVTTS--------------AETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVST 1287

Query: 300  TQSNEKHAPTY-TIPLS---PVLSPTLPAEAPTAQVPPSLPRNSTMMQAVKTTPRQRSPL 355
            T      A T  T P+    PV++    + +PT     S+P +        T    R+PL
Sbjct: 1288 TLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTS--------TYSEGRTPL 1339

Query: 356  LNQPVPELSHASL---------IANQSPF----RAPLNVTNTAGTSLPSVDLLQKLRLTP 402
             + PV     AS          + N +P      A  + T + GTS+P+ +  +      
Sbjct: 1340 TSIPVNTTLVASSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLT 1399

Query: 403  QHDQIQTQPLGKGAMVASFSPAAGQLATPESFIEPPSKTAAARVAASASLSNMVLAPLQS 462
                  T  +   A   S +P         S     S T A  ++   S  +    PL+S
Sbjct: 1400 SIPVSTTPVVSSEASTLSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKS 1459

Query: 463  MQQNQDPEVFVQPKVLSSAIQVAGAPLVTATTTAVS 498
            +  +  P    +   LS+    + +P+VT+T  + S
Sbjct: 1460 IPVSNTPVANSEASTLSTTPVDSNSPVVTSTAVSSS 1495



 Score = 38.1 bits (87), Expect = 0.022
 Identities = 58/312 (18%), Positives = 108/312 (34%), Gaps = 21/312 (6%)

Query: 268  APQSETLGVPSAAHHSVQPEITTPVLITPAS----ITQSNEKHAPTYTIPLSPVLSPTLP 323
            A  S T    ++   S   E +TP+   P S    ++  +   + T     +PV + T  
Sbjct: 3142 AHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEA 3201

Query: 324  AEAPTAQ---VPPSLPRNSTMMQAVKTTPRQRSPLLNQPVPELSHASLIANQSPFRAPLN 380
              + TA+   +P S P           TP    P+ N PV     + L         PL 
Sbjct: 3202 TSSTTAEGTSIPTSTPSEGM-------TPLTSVPVSNTPVASSEASILSTTPVDSNTPLT 3254

Query: 381  VTNTAGTSLPSVDLLQKLRLTPQHDQIQTQPLGKGAMVASFSPAAGQLATPESFIEPPSK 440
             +  A +S P+ +       TP         +       + S  +    TP     P   
Sbjct: 3255 TSTEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTP--V 3312

Query: 441  TAAARVAASASLSNMVLAPLQSMQQNQDP----EVFVQPKVLSSAIQVAGAPLVTAT-TT 495
            T  ++ ++S  +++    P  +  +   P         P V S A  ++  P+ T+T  T
Sbjct: 3313 TTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVT 3372

Query: 496  AVSSVLLAPSVFQQTVTRSSDLERKASSPSPLTIGTPESQRKPSIILSKSQLQDTLIHLI 555
              +   L+P+  + T   +S      +  + + + T          LS + +    +   
Sbjct: 3373 TSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTTPVDSNTLVTT 3432

Query: 556  KNDSSFLSTLHE 567
              ++S   T+ E
Sbjct: 3433 STEASSSPTIAE 3444



 Score = 36.2 bits (82), Expect = 0.085
 Identities = 92/434 (21%), Positives = 149/434 (34%), Gaps = 47/434 (10%)

Query: 174  GDSNISSPGLQPSTQLSNLG---------STETLEEMPSGSQDKSAPSGHKHLTVEELFG 224
            G S  +S   + ST L+N+             TL   P  +      S    L+     G
Sbjct: 3327 GTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTSTEASLSPTTAEG 3386

Query: 225  TSLPKEQPA--VVGLDSEEMERLPGDASQK--------EPNSFLPFPFEQLGGAPQSETL 274
            TS+P   P+     L S  +   P  +S+         + N+ +    E       +E  
Sbjct: 3387 TSIPTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTTPVDSNTLVTTSTEASSSPTIAEGT 3446

Query: 275  GVPSAAHH------SVQPEITTPVLITPASITQSNEKHAPTYTIPLSPVLSPTLPAEAPT 328
             +P++         S+ P  TTPV  + AS   +      T     SP  S    AE  T
Sbjct: 3447 SLPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTTSSPTNSSPTTAEV-T 3505

Query: 329  AQVPPSLPRNSTMM--QAVKTTP---RQRSPLLNQPVPELSHASLIANQSPFRAPLNVTN 383
            +    +    ST +    V TTP    + S L   PV   +  +  +  S   A L VT 
Sbjct: 3506 SMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQASSSPATLQVTT 3565

Query: 384  ------TAGTSLPSVDLLQKLRLTPQHDQIQTQPLGKGAMVASFSPAAGQLATPESFIEP 437
                  + G+S  +  LL    +T       + P    +   + S  +    TP   I  
Sbjct: 3566 MRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDRSTPVTTSTQSNSTPTPPEVITL 3625

Query: 438  PSKTAA-------ARVAASASLSNMVLAPLQSMQQNQDPEVFVQPKVLSSAIQVAGAPLV 490
            P  T +           ++ S++        ++  +    V    +V SS +   G  + 
Sbjct: 3626 PMSTPSEVSTPLTIMPVSTTSVTISEAGTASTLPVDTSTPVITSTQVSSSPVTPEGTTMP 3685

Query: 491  TATTTAVSSVLLAPSVFQQTVTRSSDLERKASSPSPLTIGTPESQRKPSIILSKSQLQDT 550
              T +  S+ L    V    VT S       S+PS +T  TP +    +I  S +    T
Sbjct: 3686 IWTPSEGSTPLTTMPVSTTRVTSSEG--STLSTPSVVT-STPVTTSTEAISSSATLDSTT 3742

Query: 551  LIHLIKNDSSFLST 564
            +   +  + S L T
Sbjct: 3743 MSVSMPMEISTLGT 3756



 Score = 34.3 bits (77), Expect = 0.32
 Identities = 76/351 (21%), Positives = 123/351 (35%), Gaps = 24/351 (6%)

Query: 197  TLEEMPSGSQDKSAPSGHKHLTVEELFGTSLPKEQPAVVGLDSEEMERLPGDASQKEPNS 256
            TL   P  S      S     +     GTS+P    +        M       +  E ++
Sbjct: 2534 TLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASSEAST 2593

Query: 257  FLPFPFE-QLGGAPQSETLGVPSAAHHSVQPEITTP----VLITPASITQSNEKHAPTYT 311
                P +  +     +ET   P+ A  +  P I+TP      +T   ++      +   T
Sbjct: 2594 LSTTPVDTSIPVTTSTETSSSPTTAKDTSMP-ISTPSEVSTSLTSILVSTMPVASSEAST 2652

Query: 312  IPLSPVLSPTLPAEAPTAQVPPSLPRNSTMMQAVKTTPRQRS-PLLNQPVPEL----SHA 366
            +  +PV + TL   +      P+    S+M  +   TP +RS PL N  V       S A
Sbjct: 2653 LSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTS---TPGERSTPLTNILVSTTLLANSEA 2709

Query: 367  SLIANQSPFRAPLNVTNTAGTSLPSVDLLQKLRLTPQHDQIQ--TQPLGKGAMVASFSPA 424
            S ++      +    T+   +S P+      +R++   D     T  L     VAS   +
Sbjct: 2710 STLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPVASSEAS 2769

Query: 425  AGQLATPESFIEPPSKTAAARVAASASLSNMVLA-------PLQSMQQNQDPEVFVQPKV 477
                   ++ I   + T A+    +A +++M  +       PL SM  N  P    +   
Sbjct: 2770 TVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGT 2829

Query: 478  LSSAIQVAGAPLVTATTTAVSSVLLAPSVFQQTVTRSSDLERKASSPSPLT 528
            LS+       P VT +T A SS   A  +     T S       S P   T
Sbjct: 2830 LSTTPVDTSTP-VTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTT 2879



 Score = 33.9 bits (76), Expect = 0.42
 Identities = 72/329 (21%), Positives = 118/329 (35%), Gaps = 66/329 (20%)

Query: 265  LGGAPQSETLGVPSAAHHSVQPEITTPVLITPASITQSNEKHAPTYTIPLSPVLSPTLP- 323
            L   P S  L V S A       + T + +T ++   S+   A   +IP SP    T P 
Sbjct: 1103 LTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPL 1162

Query: 324  ------------AEAPTAQVPP--------------SLPRNSTMMQAVKTTPRQRS-PLL 356
                        +EA T    P              S P  + +     +TP +RS PL 
Sbjct: 1163 ASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTPLT 1222

Query: 357  NQPV---PELSHASLIANQSPFRAPLNVTNTA----------GTSLP------------S 391
            + PV   P  S  +   + SP      VT +A          GTSLP            S
Sbjct: 1223 SMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTS 1282

Query: 392  VDLLQKLRLTPQHDQIQTQPLG-KGAMV------ASFSPAAGQLATPESFIEPPSKTAAA 444
            + +   L  +P+   + T P+  KG +V      +S +PA G      ++ E   +T   
Sbjct: 1283 IPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSE--GRTPLT 1340

Query: 445  RVAASASL-SNMVLAPLQSMQQNQDPEVFVQPKVLSSAIQVAGAPLVTATTTAVSSVLLA 503
             +  + +L ++  ++ L +   +    V    +  SS     G  +  +  +  ++ L +
Sbjct: 1341 SIPVNTTLVASSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTS 1400

Query: 504  PSVFQQTVTRSSDLERKASSPSPLTIGTP 532
              V    V  S   E    S +P+   TP
Sbjct: 1401 IPVSTTPVVSS---EASTLSATPVDTSTP 1426



 Score = 32.7 bits (73), Expect = 0.94
 Identities = 79/350 (22%), Positives = 122/350 (34%), Gaps = 37/350 (10%)

Query: 179  SSPGLQPSTQLSNL---------GSTETLEEMPSGSQDKSAPSGHKHLTVEELFGTSLPK 229
            S+PG + ST L+N+             TL   P  +      S     +     GTS+  
Sbjct: 2685 STPG-ERSTPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRI 2743

Query: 230  EQPA--VVGLDSEEMERLPGDASQKEPNSFLP----FPFEQLGGAPQSETLGVPSAAHHS 283
              P+     L S  +  LP  +S+    S        P      A  S T    ++   S
Sbjct: 2744 STPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTS 2803

Query: 284  VQPEITTPVLITPASITQSNEKHAPTY-TIPL---SPVLSPTLPAEAPTAQVPPSLP--- 336
               E +TP+   P + T      A T  T P+   +PV + T  + +PT      +P   
Sbjct: 2804 TPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPIST 2863

Query: 337  --RNSTMMQA--VKTTP---RQRSPLLNQPVPELSHASLIANQSPFRAPLNVTNTAGTSL 389
                ST++ +  V TTP    + S L   PV      + I   +      + T   GTS+
Sbjct: 2864 ASEGSTLLTSIPVSTTPVASSEASTLSTTPVD-----TSIPVTTSTEGSSSPTTAEGTSM 2918

Query: 390  PSVDLLQKLRLTPQHDQIQTQPL-GKGAMVASFSPAAGQLATPESFIEPPSKTAAARVAA 448
            P +    ++        + T P+ G  A   S +P   +     S     S T A   + 
Sbjct: 2919 P-ISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSM 2977

Query: 449  SASLSNMVLAPLQSMQQNQDPEVFVQPKVLSSAIQVAGAPLVTATTTAVS 498
              S       PL SM  +  P    +   LS        P+ T+T  + S
Sbjct: 2978 PISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEASSS 3027



 Score = 31.6 bits (70), Expect = 2.1
 Identities = 61/265 (23%), Positives = 95/265 (35%), Gaps = 31/265 (11%)

Query: 291  PVLITPASITQSNEKHAPTYTIPLSPVLSPTLPAEAPTAQVPPSLPRNSTMMQAVKTTPR 350
            P  +T   I+ ++E+  P  T+    ++S TLP   P A +  S P   T      +T  
Sbjct: 3858 PAEVTTIRISITSERSTPLTTL----LVSTTLPTSFPGASIA-STPPLDTSTTFTPSTDT 3912

Query: 351  QRSPLLNQPVPELSHASLIANQSPFRAPLNVTNTAGTSLPSVDLLQKLR---LTP--QHD 405
              +P +  PV      S+I   S     + + +T  TS  + D+         TP     
Sbjct: 3913 ASTPTI--PVATTISVSVITEGSTPGTTIFIPSTPVTS-STADVFPATTGAVSTPVITST 3969

Query: 406  QIQTQPLGKGAMVASFSPA------AGQLATPESFIE---PPS--KTAAARVAASASLSN 454
            ++ T      +   SFS        A   A P +++     PS  +T +     SAS  +
Sbjct: 3970 ELNTPSTSSSSTTTSFSTTKEFTTPAMTTAAPLTYVTMSTAPSTPRTTSRGCTTSASTLS 4029

Query: 455  MVLAPLQSMQQNQDP-----EVFVQPKVLSSAIQVAGAPLVTAT--TTAVSSVLLAPSVF 507
                P  S      P     E      + S  I     P  ++T  TT+ SS  + P   
Sbjct: 4030 ATSTPHTSTSVTTRPVTPSSESSRPSTITSHTIPPTFPPAHSSTPPTTSASSTTVNPEAV 4089

Query: 508  QQTVTRSSDLERKASSPSPLTIGTP 532
                TR+    R  S P+  T   P
Sbjct: 4090 TTMTTRTKPSTRTTSFPTVTTTAVP 4114


>gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]
          Length = 2089

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 73/352 (20%), Positives = 119/352 (33%), Gaps = 28/352 (7%)

Query: 197  TLEEMPSGSQDKSAPSGHKHLTVEELFGTSLPKEQPAVVGLDSEEMERLPGDASQKEPNS 256
            T+ E P+  Q        KHL    L    LP  +P V     +  +  P      E   
Sbjct: 1041 TVPEAPAPPQKPLNSQSQKHLAPPPLLSPLLPSIKPTVRKTRQDGSQEAPEAPLSSELEP 1100

Query: 257  FLPFP------FEQLGGAPQSETLGVPSAAHHSVQPEITTPVLITPASITQSNEKHAPTY 310
            F P P        ++   P +     P  +  + QP    P      S T  +    P  
Sbjct: 1101 FHPKPKIRTRKSSRMTPFPATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTPEP 1160

Query: 311  TIPLSPVLSPTLPAEAPTAQVPPS-LPRNSTMMQAVKT------TPRQRSPLLNQPVPEL 363
             +P +P L P+   + P    P S + R      +VKT      T  +  P  +   P  
Sbjct: 1161 VVPTAPELQPSTSTDQPVTSEPTSQVTRGRKSRSSVKTPETVVPTALELQPSTSTDRPVT 1220

Query: 364  SHASLIA-----NQSPFRAPLNVTNTAGTSLPSVDLLQKLRLTPQHDQIQTQPLGKGAMV 418
            S  +  A     N+S  + P  V  TA    PS    Q +   P +   + +        
Sbjct: 1221 SEPTSQATRGRKNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTYQATRGRKNRSSVKT 1280

Query: 419  AS-FSPAAGQLATPESFIEPPSKTAAARVAASASLSNMVLAPLQSMQQNQDPEVFVQPKV 477
                 P A +L    S   P +    +R   S +  + V  P        +  V   P++
Sbjct: 1281 PEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVKTP--------ETVVPTAPEL 1332

Query: 478  -LSSAIQVAGAPLVTATTTAVSSVLLAPSVFQQTVTRSSDLERKASSPSPLT 528
             +S++      P  T+ TT   + + +    + TV  + +L    S+  P+T
Sbjct: 1333 QISTSTDQPVTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTEQPVT 1384



 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 78/389 (20%), Positives = 130/389 (33%), Gaps = 50/389 (12%)

Query: 179  SSPGLQPSTQLSNLGSTETLEEMPSGSQDKSAPSGHKHL--TVEELFGTSLPKEQPAVVG 236
            ++P LQPST      ++E   +   G +++S+    + +  T  EL   S   ++P    
Sbjct: 1246 TAPELQPSTSTDQPVTSEPTYQATRGRKNRSSVKTPEPVVPTAPEL-RPSTSTDRPVTPK 1304

Query: 237  LDSEEMERLPGDASQKEPNSFLPFPFEQLGGAPQSETLGVPSAAHHSVQPEITTPVLITP 296
              S         +S K P + +P        AP+   L + ++    V P+   P   T 
Sbjct: 1305 PTSRTTRSRTNMSSVKTPETVVPT-------APE---LQISTSTDQPVTPK---PTSRTT 1351

Query: 297  ASITQSNEKHAPTYTIPLSPVLSPTLPAEAPTAQVPPSLPRNSTMMQAVKTTPRQRSPLL 356
             S T  +    P  T+P++P L P+   E P    P S        ++   TP    P  
Sbjct: 1352 RSRTNMSSVKNPESTVPIAPELPPSTSTEQPVTPEPTSRATRGRKNRSSGKTPETLVPTA 1411

Query: 357  NQPVPELSHASLIANQSPFRAPLNVTNTAGTSLPSVDLLQKLRLTPQHDQIQTQPLGKGA 416
             +  P  S    +  +   +A    TN +    P   +     L P     Q       +
Sbjct: 1412 PKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETVVPTAPELQPSTSTDQPVTPEPTS 1471

Query: 417  MVASFSPAAGQLATPESFI------------------EPPSKTAAARV-AASASLSNMVL 457
                       + TPE+ +                  EP S+T   R   +S      V+
Sbjct: 1472 QATRGRTDRSSVKTPETVVPTAPELQASASTDQPVTSEPTSRTTRGRKNRSSVKTPETVV 1531

Query: 458  APLQSMQQNQDPEVFVQPKVLSSAIQVAGAPLVTATTTAVSSVLLAPSVFQQT------- 510
                 +Q +   +  V P+  S A +  G    ++  T  S V +AP +   T       
Sbjct: 1532 PAAPELQPSTSTDQPVTPEPTSRATR--GRTNRSSVKTPESIVPIAPELQPSTSRNQLVT 1589

Query: 511  ------VTRSSDLERKASSPSPLTIGTPE 533
                   TR         +P P+    PE
Sbjct: 1590 PEPTSRATRCRTNRSSVKTPEPVVPTAPE 1618



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 80/383 (20%), Positives = 133/383 (34%), Gaps = 47/383 (12%)

Query: 179  SSPGLQPSTQLSNLGSTETLEEMPSGSQDKSAPSGHKHL--TVEELFGTSLPKEQPAVVG 236
            ++P LQPST      + E   +   G  D+S+    + +  T  EL   S   +QP    
Sbjct: 1451 TAPELQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPEL-QASASTDQPVTSE 1509

Query: 237  LDSEEMERLPGDASQKEPNSFLPFPFEQLGGAPQSETLGVPSAAHHSVQPEITTPVLITP 296
              S         +S K P + +P        AP+ +    PS +  + QP    P     
Sbjct: 1510 PTSRTTRGRKNRSSVKTPETVVP-------AAPELQ----PSTS--TDQPVTPEPTSRAT 1556

Query: 297  ASITQSNEKHAPTYTIPLSPVLSPTLPAEAPTAQVPPSLPRNSTMMQAVKTTPRQRSPLL 356
               T  +    P   +P++P L P+          P S        ++   TP    P  
Sbjct: 1557 RGRTNRSSVKTPESIVPIAPELQPSTSRNQLVTPEPTSRATRCRTNRSSVKTPEPVVPTA 1616

Query: 357  NQPVPELSHASLIANQSPFRAPLNVTNTAGTSLP------SVDLLQKLRLTPQHDQIQTQ 410
             +P P  S    +  +   RA    TN +    P      + DL      TP    +  +
Sbjct: 1617 PEPHPTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPVEPAASDLEP---FTPTDQSVTPE 1673

Query: 411  PLGKG------------AMVASFSPAAGQLATPESFIEPPSKTAAARVAASASLSN--MV 456
             + +G            AM    +P      T +  I P   T  + +    +  N   +
Sbjct: 1674 AIAQGGQSKTLRSSTVRAMPVPTTPEFQSPVTTDQPISPEPITQPSCIKRQRAAGNPGSL 1733

Query: 457  LAPLQSMQQNQDPEVFVQPKVLSSAIQVAGAPLVTATTTAVSSVLLAPSVFQQTVTRSSD 516
             AP+     ++     ++PK  +S  Q  GA     + TA+     A     +T   +S 
Sbjct: 1734 AAPI----DHKPCSAPLEPKSQASRNQRWGAVRAAESLTAIPEP--ASPQLLETPIHASQ 1787

Query: 517  LERKASSPSPLTIGTPESQRKPS 539
            +++    P+  +  TPE Q K S
Sbjct: 1788 IQK--VEPAGRSRFTPELQPKAS 1808



 Score = 36.6 bits (83), Expect = 0.065
 Identities = 91/438 (20%), Positives = 146/438 (33%), Gaps = 63/438 (14%)

Query: 127  EEETRRSQQAARDKQ---SPSQANGCSDHRPIDILEMLSRAKDEYERNQMGDSNISSPGL 183
            +++  + Q  ARD Q   S       S  R  + L++     +E +  Q+    + S   
Sbjct: 856  KQDREQKQLLARDTQRQESDKNGESASPERDRESLKVEIETSEEIQEKQVQKQTLPSKAF 915

Query: 184  QPSTQLS----NLGSTETLEEMPSGSQDKSAPSGHKHLTVEELFG-TSLPKEQPAVVGLD 238
            +   +           E  E++P    ++    G      ++  G  S P  +P V   D
Sbjct: 916  EREVERPVANRECDPAELEEKVPKVILERDTQRGEPEGGSQDQKGQASSPTPEPGVGAGD 975

Query: 239  SEEMERLPGDASQKEPNSFLPFPFEQLGG-----APQSETLGVPSAAHHSVQPEITTPVL 293
                  LPG  S   P+        Q GG     +P+    G+ +       P       
Sbjct: 976  ------LPGPTSAPVPSG------SQSGGRGSPVSPRRHQKGLLNCK----MPPAEKASR 1019

Query: 294  ITPASITQSNEKHAPTYTIPLSPVLSPTLPAEAPTAQVPPSLPRNSTMMQAVKTTPRQRS 353
            I  A      ++ +P   +P      PT+P EAP    PP  P NS   Q     P   S
Sbjct: 1020 IRAAEKVSRGDQESPDACLP------PTVP-EAPA---PPQKPLNS-QSQKHLAPPPLLS 1068

Query: 354  PLLNQPVPELSHASLIANQSPFRAPLNVTNTAGTSLPSVDLLQKLRLTPQHDQIQTQPLG 413
            PLL    P +       +Q    APL+         P +   +  R+TP        P  
Sbjct: 1069 PLLPSIKPTVRKTRQDGSQEAPEAPLSSELEPFHPKPKIRTRKSSRMTP-------FPAT 1121

Query: 414  KGAMVASFSPAAGQLATPESFIEPPSKTAAARVAASASLSNMVLAPLQSMQQ---NQDPE 470
              A     S +  Q  TP    +P S+   +R   S+  +   + P     Q   + D  
Sbjct: 1122 SAAPEPHPSTSTAQPVTP----KPTSQATRSRTNRSSVKTPEPVVPTAPELQPSTSTDQP 1177

Query: 471  VFVQPKVLSSAIQVAGAPLVTATTTAVSSVLLAPSVF---------QQTVTRSSDLERKA 521
            V  +P    +  + + + + T  T   +++ L PS               TR        
Sbjct: 1178 VTSEPTSQVTRGRKSRSSVKTPETVVPTALELQPSTSTDRPVTSEPTSQATRGRKNRSSV 1237

Query: 522  SSPSPLTIGTPESQRKPS 539
             +P P+    PE Q   S
Sbjct: 1238 KTPEPVVPTAPELQPSTS 1255


>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
          Length = 3230

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 80/328 (24%), Positives = 117/328 (35%), Gaps = 64/328 (19%)

Query: 268  APQSETLGVPSAAHHSVQPEITTPVLITPASITQSNEKHAPTYTIPLSPVLSPTLPAEAP 327
            AP    + VP++A  S  P    P     AS+       +     PL+P+ +P     AP
Sbjct: 1542 APACSPVLVPASALASPFPSAPNPAP-AQASLLAPASSASQALATPLAPMAAPQTAILAP 1600

Query: 328  TAQVPPSLPRNSTMMQAVKTTPRQRSPLLNQ--PVPELSHASL----IANQSPFRAPLNV 381
            +   PP  P     +  +  +P     L +   PVP ++ +S     +A+ SP  AP  V
Sbjct: 1601 SP-APPLAP-----LPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAPTPV 1654

Query: 382  TNTAGTS----------LPSVDLLQKLRLTPQ-------HDQIQTQPLGKG-------AM 417
               + T           LPS    Q L L P            QT  LG G         
Sbjct: 1655 LAPSSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQ 1714

Query: 418  VASFSPAAGQLATPESFIE----------------PPSKTAAARVAASASLSNMVLAPLQ 461
              S +PA+  + TP   +                 P    A A     A    + LAP  
Sbjct: 1715 TLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLSLAPAPPLAPASPVGPAPAHTLTLAPAS 1774

Query: 462  SMQQNQDPEVFVQPKVLSSAIQVAGAPLVTATTTAVSSVLLAPSVFQQTVTRSSDLERKA 521
            S      P   VQ   LS A      P+ T    A  ++ LAP+  Q   +++S L   A
Sbjct: 1775 SSASLLAP-ASVQTLTLSPA------PVPTLGPAAAQTLALAPASTQSPASQASSLVVSA 1827

Query: 522  SSPSPLTI----GTPESQRKPSIILSKS 545
            S  +PL +      P S+ +P  +  +S
Sbjct: 1828 SGAAPLPVTMVSRLPVSKDEPDTLTLRS 1855



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 72/307 (23%), Positives = 112/307 (36%), Gaps = 23/307 (7%)

Query: 244  RLP----GDASQKEPNSFLPFPFEQLGGAPQSE-TLGVPSAAHHSVQPEITTPVLI---- 294
            RLP    G A    P   L  P  +L  +P  E +   P AA  ++   +  P  +    
Sbjct: 1352 RLPTPTLGTARAPMPTPTLVRPLLKLVHSPSPEVSASAPGAAPLTISSPLHVPSSLPGPA 1411

Query: 295  -TPASITQSNEKHAPTYTIPLSPVLSPTLPAEAPTAQVPPSLPRNSTMMQAVKTTPRQRS 353
             +P  I  S+   +P  +    P LS +LP   PT    P+    +  + A  T      
Sbjct: 1412 SSPMPIPNSSPLASPVSSTVSVP-LSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGP 1470

Query: 354  PLLNQPVPELSHASLIANQSPFRAPLNVTNTAGT------SLPSVDLLQKLRLTPQHDQI 407
             LL    P L+     A   P  AP   + +A        + PS+   Q    TP H  +
Sbjct: 1471 ALLTSVTPPLAPVVPAAPGPPSLAPSGASPSASALTLGLATAPSLSSSQ----TPGHPLL 1526

Query: 408  QTQPLGK-GAMVASFSPAAGQLATPESFIEPPSKTAAARVAASASLSNMVLAPLQSMQQN 466
                      + ++ +PA   +  P S +  P  +A     A ASL     +  Q++   
Sbjct: 1527 LAPTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALATP 1586

Query: 467  QDPEVFVQPKVLSSAIQVAGAPL-VTATTTAVSSVLLAPSVFQQTVTRSSDLERKASSPS 525
              P    Q  +L+ +     APL V A +   + VL +       +  SS      +S S
Sbjct: 1587 LAPMAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASAS 1646

Query: 526  PLTIGTP 532
            P+   TP
Sbjct: 1647 PVPAPTP 1653



 Score = 39.3 bits (90), Expect = 0.010
 Identities = 61/253 (24%), Positives = 94/253 (37%), Gaps = 54/253 (21%)

Query: 290  TPVLITPASITQSNEKHAPTYTIPLSPVLSPTLPAEAPTAQVPPSLPRNSTMMQ-AVKTT 348
            TPV + P+S            T P    LS  L A     QVPP++  N+ +++  V+  
Sbjct: 1270 TPVSVLPSSTPS---------TTPAPTGLSLPLAAN----QVPPTMVNNTGVVKIVVRQA 1316

Query: 349  PRQR----SPLLNQPVPELSHASLIANQ----SPFRAPLNVTNTAGTSLPSVDLLQKLRL 400
            PR       PL   P P  S    + N     +P R P     TA   +P+  L++ L  
Sbjct: 1317 PRDGLTPVPPLAPAPRPPSSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLVRPL-- 1374

Query: 401  TPQHDQIQTQPLGKGAMVASFSPAAGQLATPESFIEPPSKTAAARVAASASLSNMVLAPL 460
                            +    SP+             P  +A+A  AA  ++S+ +  P 
Sbjct: 1375 ----------------LKLVHSPS-------------PEVSASAPGAAPLTISSPLHVPS 1405

Query: 461  QSMQQNQDPEVFVQPKVLSSAIQ-VAGAPLVTATTTAVSSVLLAPSVFQQTVTRSSDLER 519
                    P        L+S +      PL ++   +V + L AP+    T+  S+ L  
Sbjct: 1406 SLPGPASSPMPIPNSSPLASPVSSTVSVPLSSSLPISVPTTLPAPASAPLTIPISAPLTV 1465

Query: 520  KASSPSPLTIGTP 532
             AS P+ LT  TP
Sbjct: 1466 SASGPALLTSVTP 1478



 Score = 36.2 bits (82), Expect = 0.085
 Identities = 67/302 (22%), Positives = 108/302 (35%), Gaps = 35/302 (11%)

Query: 225  TSLPKEQPAVVGLDSEEMERLPGDASQKEPNSFLPFPFEQL--GGAPQSETLGVPSAAHH 282
            +S P   PA  GL       LP  A+Q  P         ++    AP+     VP  A  
Sbjct: 1277 SSTPSTTPAPTGLS------LPLAANQVPPTMVNNTGVVKIVVRQAPRDGLTPVPPLAPA 1330

Query: 283  SVQPEITTPVLITPASITQSNEKHAPTYTIPLSPVLSPTLP------AEAPTAQVPPSLP 336
               P    P ++ P           PT     +P+ +PTL         +P+ +V  S P
Sbjct: 1331 PRPPSSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLVRPLLKLVHSPSPEVSASAP 1390

Query: 337  RNSTM-MQAVKTTPRQRSPLLNQPVPELSHASLIANQSPFRAPLNVTNTAGTSLPSVDLL 395
              + + + +    P       + P+P       I N SP  +P++ T +   S  S+ + 
Sbjct: 1391 GAAPLTISSPLHVPSSLPGPASSPMP-------IPNSSPLASPVSSTVSVPLS-SSLPIS 1442

Query: 396  QKLRLTPQHDQIQTQPLGKGAMVASFSPAAGQLATP------ESFIEPPS-KTAAARVAA 448
                L        T P+     V++  PA     TP       +   PPS   + A  +A
Sbjct: 1443 VPTTLPAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPAAPGPPSLAPSGASPSA 1502

Query: 449  SASLSNMVLAPLQSMQQNQDPEVFVQPKV-----LSSAIQVAGAPLVTATTTAVSSVLLA 503
            SA    +  AP  S  Q     + + P       L+S +  A +P++   +   S    A
Sbjct: 1503 SALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAPACSPVLVPASALASPFPSA 1562

Query: 504  PS 505
            P+
Sbjct: 1563 PN 1564



 Score = 33.1 bits (74), Expect = 0.72
 Identities = 52/233 (22%), Positives = 81/233 (34%), Gaps = 27/233 (11%)

Query: 245  LPGDASQKEPNSFLPFPFEQLGGAPQSETLGVPSAAHHSVQPEITTPVLITPA------S 298
            L G  S+ E ++FLP    +L      E    P         ++    ++ P       +
Sbjct: 951  LEGRVSRYEADTFLPR--HRLSRRVLLEVATAPDPPPRPKPVKMKVNRMLQPVPKQEGRT 1008

Query: 299  ITQSNEKHAPTYTIPLSPVLSPTLPAEAPTAQVPPSLPRNSTMMQAVKTTP------RQR 352
            +   N   AP   +P+ P   P L A+     VP  LP  S M+ A    P      R  
Sbjct: 1009 VVVVNNPRAPLGPVPVRPPPGPELSAQPTPGPVPQVLPA-SLMVSASPAGPPLIPASRPP 1067

Query: 353  SPLLNQPVPELSHASLIANQSPFRAPLNVTNTAGTSLPSVDLLQKLRLTPQHDQIQTQPL 412
             P+L  P+   S         P   P  +   +GTS P    L  L+ TP    ++  P 
Sbjct: 1068 GPVLLPPLQPNS------GSLPQVLPSPLGVLSGTSRPPTPTL-SLKPTPP-APVRLSPA 1119

Query: 413  GKGAMVASFSPAAGQLATPESFIEPPSKTAAARVAASASLSNMVLAPLQSMQQ 465
                  +   P    L  P  +  PP+         + + +  V AP  + Q+
Sbjct: 1120 PPPGSSSLLKP----LTVPPGYTFPPAAATTTSTTTATATTTAVPAPTPAPQR 1168



 Score = 31.2 bits (69), Expect = 2.7
 Identities = 68/271 (25%), Positives = 97/271 (35%), Gaps = 28/271 (10%)

Query: 199  EEMPSGSQDKSAPSGHKHLTVEELFGTSLPKEQPAVVGLDSEEMERLPGDASQKEPNSFL 258
            EE+    +   A         EE+F   LP+E+    G   E      G   ++   +  
Sbjct: 2330 EELKQAEEQVEAARKDLDQAKEEVF--RLPQEEEEGPGAGDESSCGTGGGTHRRSKKAKA 2387

Query: 259  PFP-----FEQLGGAPQSETLGV---PSAAHHSVQPEITTPVLITPASITQSNEKHAPTY 310
            P        E+L GA ++ET G    P  + H  +   TTP   +PA          P  
Sbjct: 2388 PERPGTRVSERLRGA-RAETQGANHTPVISAHQTR-STTTPPRCSPARERVPRPAPRPRP 2445

Query: 311  TIPLSPVLSPTLPAEAPTAQVPPSLPRNSTMMQAVKTTPRQRSPLLNQPVPELSHASLIA 370
            T   +P   P L     +A VP S P   T++  V   P   SP     +P  S  +   
Sbjct: 2446 TPASAPAAIPALVPVPVSAPVPISAPNPITIL-PVHILP---SPPPPSQIPPCSSPACTP 2501

Query: 371  NQSPFRAPLNVTNTAGTSL--PSVDLLQKLRLTPQHDQIQTQPLGKGAMVASFSPAAGQL 428
              +    P +    A T L  PS  LL      P    +   PLG   +       A  L
Sbjct: 2502 PPACTPPPAHTPPPAQTCLVTPSSPLLLGPPSVPISASVTNLPLG---LRPEAELCAQAL 2558

Query: 429  ATPESFIEPPSKTAAARVAASASLSNMVLAP 459
            A+PES          A VA+S + S  ++ P
Sbjct: 2559 ASPESL-------ELASVASSETSSLSLVPP 2582



 Score = 30.0 bits (66), Expect = 6.1
 Identities = 41/173 (23%), Positives = 67/173 (38%), Gaps = 25/173 (14%)

Query: 359  PVPELSHASLIANQSPFRAPLNVTNTAGTSLPSVDLLQKLRLTPQHDQI-QTQPLGKGAM 417
            PVP++  ASL+ + SP   PL       +  P   LL  L+  P    + Q  P   G +
Sbjct: 1040 PVPQVLPASLMVSASPAGPPL----IPASRPPGPVLLPPLQ--PNSGSLPQVLPSPLGVL 1093

Query: 418  VASFSPAAGQLATPESFIEPPSKTAAARVAASASLSNMVLAPLQSMQQNQDPEVFVQPKV 477
              +  P      TP   ++P          A    S+ +L PL        P  +  P  
Sbjct: 1094 SGTSRPP-----TPTLSLKPTPPAPVRLSPAPPPGSSSLLKPLTV------PPGYTFPPA 1142

Query: 478  LSSAIQVAGAPLVTATTTAVSSVLLAPSVFQQTVTRSSDLERKASSPSPLTIG 530
             ++          T T TA ++ + AP+   Q +  S D++ +  S   ++IG
Sbjct: 1143 AATTTS-------TTTATATTTAVPAPTPAPQRLILSPDMQARLPSGEVVSIG 1188


>gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein
           [Homo sapiens]
          Length = 3969

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 91/414 (21%), Positives = 148/414 (35%), Gaps = 59/414 (14%)

Query: 154 PIDILEMLSRAKDEYERNQMGDSNISSPGLQPSTQLSNLGSTETLEEMPSGSQDKSAPSG 213
           PI I  + S     +     G S  SS   Q S+Q+S+  S  +   + + S D  A   
Sbjct: 437 PIKIARLESTPNSRFSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDT-STDSQASEE 495

Query: 214 HKHLTVEELFGTSLPKEQPAVVGLDSEEMERLPG--DASQKEPNSFLPFPFEQLGGAPQS 271
            + L  E      +    P     ++E  +R       S++   S        L  APQ 
Sbjct: 496 IQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGSRTTKKLSTLQSAPQQ 555

Query: 272 ETLGVPSAAHHSVQPEITTPVLITPASITQSNEKHAPTYTIPLSPVLSPTLPAE-APTAQ 330
           +T   P        P +T P  + PAS   S   H P    P  P+ SP LPA  AP   
Sbjct: 556 QTSSSPPP------PLLTPPPPLQPAS---SISDHTPWLMPPTIPLASPFLPASTAPMQG 606

Query: 331 VPPSLPRNSTMM-----------QAVKTTPRQRSPLLNQPV-PELSHASLIANQSPFRAP 378
              S+ R  T             Q   +    +  L+ +P+        L      F + 
Sbjct: 607 KRKSILREPTFRWTSLKHSRSEPQYFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASG 666

Query: 379 LNVTNTAGTSLPSVDLLQKLRLTPQHDQIQTQPLGKGAMVASFSPAAGQLATPESFIEPP 438
            + + TA     S  L   L    + D  +  PL        F+P+       ES   P 
Sbjct: 667 FSASGTAA----SARLFSPLHSGTRFDMHKRSPL---LRAPRFTPSEAHSRIFESVTLPS 719

Query: 439 SKTAAARVAASASLSN-----MVLAPLQSMQQNQDPEV--------------FVQPKVLS 479
           ++T+A    +S+ +SN      V +P++S  ++    +                 P  +S
Sbjct: 720 NRTSAG--TSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVS 777

Query: 480 SAIQVAGAPLVTATTTAVSSVLLAPSVFQQTVTRSSDLERKASSPSPLTIGTPE 533
           S++ ++ +PL    T+A++     PS    ++T+S +   K   P   T    E
Sbjct: 778 SSLSISVSPL---ATSALNPTFTFPS---HSLTQSGESAEKNQRPRKQTSAPAE 825



 Score = 33.1 bits (74), Expect = 0.72
 Identities = 37/157 (23%), Positives = 56/157 (35%), Gaps = 20/157 (12%)

Query: 203  SGSQDKSAPSGHKHLTVEELFGTSLPKEQPAVVGLDSEEMERLPGDASQKEPNSFLPFPF 262
            S  +D    S  K++       T   +E PA     SE   R P +   +E N   P   
Sbjct: 1223 SEKKDSKESSVVKNVVDSSQKPTPSAREDPAPKKSSSEPPPRKPVEEKSEEGNVSAP--- 1279

Query: 263  EQLGGAPQSETLGVPSAAHHSVQPEITTPVLITPASITQSNEKHAPTYTIPLSPVLSPTL 322
                  P+S+    P++   S Q  ++ P L+ P           P  T P    +  T 
Sbjct: 1280 -----GPESKQATTPASRKSSKQ--VSQPALVIPPQ---------PPTTGPPRKEVPKTT 1323

Query: 323  PAEAPTAQVPPSLPRNSTMMQAVKTTPRQRSPLLNQP 359
            P+E P  + PP         +  K  PR   P+  +P
Sbjct: 1324 PSE-PKKKQPPPPESGPEQSKQKKVAPRPSIPVKQKP 1359


>gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]
          Length = 825

 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 77/368 (20%), Positives = 128/368 (34%), Gaps = 78/368 (21%)

Query: 202 PSGSQDKSAPSGHKHLTVEELFGTSLPKEQPAVVGLD------------SEEMERLPGDA 249
           P  S  KS     KH +  ++F +  P+ QPA    +            ++E ++ P   
Sbjct: 170 PDSSSTKSKEDALKHKSSGKIFASEHPEFQPATNSNEEIGQKNISRTSFTQETKKGPPVL 229

Query: 250 SQKEPNSFLPFPFEQLGGAPQSETLGVPSAAHHSVQPEITT--PVLITPASITQSNEKHA 307
            + E    +  P  Q G A       V   A   ++P  T   P  I P  + ++  K  
Sbjct: 230 LEDELREEVTVPVVQEGSA-------VKKVASAEIEPPSTEKFPAKIQPPLVEEATAKAE 282

Query: 308 PTYTIPLSPVLSPTLPAEAPTAQVPPSLPRNSTMMQAVKTTPRQRSPLLNQP-------V 360
           P         + P+   E P A+   ++  NS  +Q     P + +PL+  P        
Sbjct: 283 PRPAEETHVQVQPS-TEETPDAEAATAVAENSVKVQ---PPPAEEAPLVEFPAEIQPPSA 338

Query: 361 PELSHASLIANQSPFRA--------PLNVTNTAGTSLPSVDLLQKLRL-TPQHDQIQTQP 411
            E     L+A   P  A        P  +        PSV+LL ++R  + Q   I+ QP
Sbjct: 339 EESPSVELLAEILPPSAEESPSEEPPAEILPPPAEKSPSVELLGEIRSPSAQKAPIEVQP 398

Query: 412 LGKGAMVASFSPAAGQLATPESFIEPPSKTAAARVAASASLSNMVLAPLQSMQQNQDPEV 471
           L          PA G L    + +EPP+                 LA +Q +   + P  
Sbjct: 399 L----------PAEGALEEAPAKVEPPT-------------VEETLADVQPLLPEEAPRE 435

Query: 472 FVQPKVLSSAIQVAGAPLVTATTTAVSSVLLAPSVFQQTVTRSSDLERKASSPSPLTIGT 531
             +   LS+A++                   AP+ FQ  + + +  E  ++    L    
Sbjct: 436 EARELQLSTAMETPAEE--------------APTEFQSPLPKETTAEEASAEIQLLAATE 481

Query: 532 PESQRKPS 539
           P +   P+
Sbjct: 482 PPADETPA 489



 Score = 31.6 bits (70), Expect = 2.1
 Identities = 49/216 (22%), Positives = 72/216 (33%), Gaps = 24/216 (11%)

Query: 277 PSAAHHSVQPEITTPVLITPASITQSNEKHAPTYTIPL--SPVLSPTLPAEAPTAQVPPS 334
           P +   +   E +  + +  A+   + E  A     P   +P      PAE   A+V P 
Sbjct: 578 PPSGEETTAEEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQP- 636

Query: 335 LPRNSTMMQAVKTTPRQRSPLLNQPVPELSHASLIANQSPFRAPLNVTNTAGTSLPSVDL 394
            P        V+  P + +P   QP P     + +       AP  V +      P  + 
Sbjct: 637 -PPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQSLPAEETPIEET 695

Query: 395 LQKLRLTPQHDQIQTQPLGKGAMVASFSPAAGQLATPESFIEPPSKTAAARVAASASLSN 454
           L  +   P  D    +     A V   SP A  L T E     P   A+A V        
Sbjct: 696 LAAVHSPPADDVPAEE-----ASVDKHSPPADLLLTEEF----PIGEASAEV-------- 738

Query: 455 MVLAPLQSMQQNQDPEVFVQPKVLSSAIQVAGAPLV 490
              +P  S Q  +D  +         + QVAG P V
Sbjct: 739 ---SPPPSEQTPEDEALVENVSTEFQSPQVAGIPAV 771


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 86/353 (24%), Positives = 123/353 (34%), Gaps = 51/353 (14%)

Query: 185 PSTQLSNLGSTETLEEMPSGSQDKSAPSGHKHLTVEELFGTSLPKEQPAVVGLDSEEMER 244
           P   +S+     T E  P+  +  SA  G +      L  ++ P   PA  G  +    R
Sbjct: 196 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPR 255

Query: 245 LPGDASQKEPNSFLPFPFEQLG----------GAPQSETLGVPSAA---HHSVQPEITT- 290
            P   SQ +P         Q+           G   S  L  PS +     S  P + T 
Sbjct: 256 APAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTL 315

Query: 291 --PVLITPASITQS------NEKHAPTYTIPLSPVLSPTLPAEAPTA------QVPPSLP 336
             P    P+  T S         H+   + PLSP+ +P  P +AP A      Q PPS P
Sbjct: 316 PSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATP--PPQAPPALALPPLQAPPSPP 373

Query: 337 RNSTMMQAVKTTPRQRSPLLNQPVPELSHASLI-ANQSPFRAPLNVTNTAGTSLPSVDLL 395
            +  +           SPL   P P+  +A  +   Q+PF  P +    A  S P+   +
Sbjct: 374 ASPPL-----------SPLAT-PSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPV 421

Query: 396 QKLRLTPQH--DQIQTQPLGKGAMVASFSPAAGQLATPESFIEPPSKTAAARVAASASLS 453
                 P      +   PL       + SP     ATP     PP      ++A     +
Sbjct: 422 SPSATPPSQAPPSLAAPPLQVPPSPPA-SPPMSPSATPPPQAPPPLAAPPLQLAKPPPQA 480

Query: 454 NMVLA--PLQSMQQNQDPEVFVQPKVLSSAIQVAGAPLVTATTTAVSSVLLAP 504
              LA  PLQ++     P  F      S +  +  +PL T    A   VL AP
Sbjct: 481 PPALATPPLQALP--SPPASFPGQAPFSPSASLPMSPLATPPPQA-PPVLAAP 530



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 70/278 (25%), Positives = 101/278 (36%), Gaps = 29/278 (10%)

Query: 202 PSGSQDKSAPSGHKHLTVEELFGTSLPKEQPAVVGLDSEEMERLPGDASQKEPNSFLPFP 261
           P+    KS  S  +H T E    +   + +P+  G        L   AS+   +S  P  
Sbjct: 192 PTEGPRKSVSSASEHSTTEP---SPAARRRPSAGG-------GLQRPASRSLSSSATPLS 241

Query: 262 FEQLGGAPQSETLGVPSAAHHSVQPEITTPVLITPASITQSNEKHAPTY-TIPLSPVLSP 320
                G       G P A  H  QP+      + P  +T   +  AP    +  SP+ +P
Sbjct: 242 SPARSGP---SARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATP 298

Query: 321 TLPAEAPTAQVPPSLPRNSTMMQAVKTTPRQRSPLLNQPVPELSHASLIANQSPFRAPLN 380
           + P+  P+   PPSL    T+     T P Q +  L  P  + +H+ L    SP   PL+
Sbjct: 299 S-PSAPPSPSAPPSL---QTLPSPPATPPSQATTSLGSPTLQATHSFL---PSP---PLS 348

Query: 381 VTNTAGTSLPSVDLLQKLRLTPQHD-QIQTQPLGKGAMVASFSPAAGQLATPESFIEPPS 439
              T     P    L  L+  P         PL   +  A  + A   L  P  F  PPS
Sbjct: 349 PLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAP--FSPPPS 406

Query: 440 KTAAARVA--ASASLSNMVLAPLQSMQQNQDPEVFVQP 475
               A  +  AS  +S     P Q+      P + V P
Sbjct: 407 PPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPP 444


>gi|26051278 nuclear pore membrane protein 121 [Homo sapiens]
          Length = 984

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 93/406 (22%), Positives = 137/406 (33%), Gaps = 57/406 (14%)

Query: 135 QAARDKQSPSQANGCSDHRPIDILEMLSRAKDEYERNQMGDSNISSPGLQPSTQLSNLGS 194
           ++ +  Q+P     C +       E LS  K       +G S    PGL PS    +   
Sbjct: 334 ESLKKMQTPPSLPPCPESAGAATTEALSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPP 393

Query: 195 TETLEEMPSGSQ----DKSAPSGHKHLTVEELFGTSLPKEQPA---VVGLDSEEMERLPG 247
           T  L  +P+ S     D  AP   +  T  +   TS P   P    + G  +        
Sbjct: 394 TTLLGLIPAPSMVPATDTKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQNTSPSSPAA 453

Query: 248 DASQKEPNSFLPFPFEQLGGAPQSETLGVPSAAHHSVQPEITTPVLITPASITQSNEKHA 307
            A+   P  F P         P+SE  G P+    SV             + T  +    
Sbjct: 454 PAASSAPPMFKPI----FTAPPKSEKEG-PTPPGPSV-------------TATAPSSSSL 495

Query: 308 PTYTIPLSPVLSPTLPAEAPTAQVPPSLP--RNSTMMQAVKTTPRQRSPLLNQPVPELSH 365
           PT T   +P   P   +  P A VP   P  + +T      T P   +PL        S 
Sbjct: 496 PTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQTT---TPATAPTTTAPLFTGLASATSA 552

Query: 366 ASLIANQSPFRAPLNVTNTAGTSLPSVDLLQKLRLTPQHDQIQTQPLGKG---AMVASFS 422
            + I + SP     +     G  + SV     +  T       +QP   G   A  ASF+
Sbjct: 553 VAPITSASPSTDSAS-KPAFGFGINSVS-SSSVSTTTSTATAASQPFLFGAPQASAASFT 610

Query: 423 PAAGQLATPESFIEPPSKTAAARVAASASLSNMVLAPLQSMQQNQDPEVFVQPKVLSSAI 482
           PA G +     F +PP+      V                   +Q     V     SSA 
Sbjct: 611 PAMGSIF---QFGKPPALPTTTTVTTF----------------SQSLHTAVPTATSSSAA 651

Query: 483 QVAGAPLVTATTTAVSSVLLAPSV-FQQTVTRSSDLERKASSPSPL 527
             +G     AT+   +S    P++ F  T T + ++   +S+ SPL
Sbjct: 652 DFSGFGSTLATSAPATS--SQPTLTFSNTSTPTFNIPFGSSAKSPL 695


>gi|222418647 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 58/231 (25%), Positives = 87/231 (37%), Gaps = 25/231 (10%)

Query: 175 DSNISSPGLQPSTQLSNL----GSTE--TLEEMPSGSQDKSAPSGHKHLTVEELFGTSLP 228
           +S++ +P L  +TQ+ ++     ST+  TL  +    Q+ +  S  +++       T  P
Sbjct: 97  NSSVVNPTLVATTQIPSVTFPSASTKITTLPNVTFLPQNATTISSRENVNTSSSVATLAP 156

Query: 229 KEQPAVVGLDSEEMERLPGDASQKEPNSFLPFPFEQLGGAPQSETLGVPSAAHHSVQPEI 288
              PA    D+      P   +   P+S  P         P + T   PS+   S  PE 
Sbjct: 157 VNSPAPQ--DTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSS---SAPPET 211

Query: 289 TTPVLITPASITQSNEKHAPTYTIPLSPVLSPTLPA----EAP--TAQVPPSLPRN---- 338
           T      PA+        AP  T    P  S T PA     AP  T  VPP+        
Sbjct: 212 TAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTAVPPTPSATTLDP 271

Query: 339 STMMQAVKTTPRQRSPLLNQPVPELSHASLIANQSPFRAPLNVTNTAGTSL 389
           S+     +TT    +P    P P  S A     Q    AP+   N++ T+L
Sbjct: 272 SSASAPPETTAAPPTPSATTPAPPSSPAP----QETTAAPITTPNSSPTTL 318



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 56/230 (24%), Positives = 82/230 (35%), Gaps = 21/230 (9%)

Query: 303 NEKHAPTYTIPLSPVLSPTLPAEAPTAQVP----PSLPRNSTMMQAVKTTPRQRSPLLNQ 358
           N    P +    S V++PTL A   T Q+P    PS     T +  V   P+  + + ++
Sbjct: 86  NPHQPPKHPDKNSSVVNPTLVA---TTQIPSVTFPSASTKITTLPNVTFLPQNATTISSR 142

Query: 359 PVPELSHASLIANQSPFRAPLNVTNTAGTSLPSVDLLQKLRLTPQHDQIQTQPLGKGAMV 418
               ++ +S +A  +P  +P     TA    PS         TP        P       
Sbjct: 143 E--NVNTSSSVATLAPVNSPAPQDTTAAPPTPSAT-------TPAPPSSSAPP---ETTA 190

Query: 419 ASFSPAAGQLATPESFIEPPSKTAAARVAASASLSNMVLAPLQSMQQNQDPEVFVQPKVL 478
           A  +P+A   A P S   P +  A     A+        AP ++      P       + 
Sbjct: 191 APPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLS 250

Query: 479 SSAIQVAGA--PLVTATTTAVSSVLLAPSVFQQTVTRSSDLERKASSPSP 526
           SSA     A  P  +ATT   SS    P       T S+      SSP+P
Sbjct: 251 SSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPAP 300



 Score = 35.4 bits (80), Expect = 0.15
 Identities = 38/141 (26%), Positives = 47/141 (33%), Gaps = 27/141 (19%)

Query: 246 PGDASQKEPNSFLPFPFEQLGGAPQSETLGVPSAAHHSVQPEIT----TPVLITPASITQ 301
           P   +Q  P+S  P    +   AP +     P+    S  PE T    TP   TPA ++ 
Sbjct: 195 PSATTQAPPSSSAP---PETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSS 251

Query: 302 SNEKHAPTYTIPLSPVLSPTL----------------PAEAPTAQVPPSLPRNSTMMQAV 345
           S    AP  T  + P  S T                 P  + T   PPS P       A 
Sbjct: 252 S----APPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPAPQETTAAP 307

Query: 346 KTTPRQRSPLLNQPVPELSHA 366
            TTP      L     E S A
Sbjct: 308 ITTPNSSPTTLAPDTSETSAA 328


>gi|222418649 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 58/231 (25%), Positives = 87/231 (37%), Gaps = 25/231 (10%)

Query: 175 DSNISSPGLQPSTQLSNL----GSTE--TLEEMPSGSQDKSAPSGHKHLTVEELFGTSLP 228
           +S++ +P L  +TQ+ ++     ST+  TL  +    Q+ +  S  +++       T  P
Sbjct: 97  NSSVVNPTLVATTQIPSVTFPSASTKITTLPNVTFLPQNATTISSRENVNTSSSVATLAP 156

Query: 229 KEQPAVVGLDSEEMERLPGDASQKEPNSFLPFPFEQLGGAPQSETLGVPSAAHHSVQPEI 288
              PA    D+      P   +   P+S  P         P + T   PS+   S  PE 
Sbjct: 157 VNSPAPQ--DTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSS---SAPPET 211

Query: 289 TTPVLITPASITQSNEKHAPTYTIPLSPVLSPTLPA----EAP--TAQVPPSLPRN---- 338
           T      PA+        AP  T    P  S T PA     AP  T  VPP+        
Sbjct: 212 TAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTAVPPTPSATTLDP 271

Query: 339 STMMQAVKTTPRQRSPLLNQPVPELSHASLIANQSPFRAPLNVTNTAGTSL 389
           S+     +TT    +P    P P  S A     Q    AP+   N++ T+L
Sbjct: 272 SSASAPPETTAAPPTPSATTPAPPSSPAP----QETTAAPITTPNSSPTTL 318



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 56/230 (24%), Positives = 82/230 (35%), Gaps = 21/230 (9%)

Query: 303 NEKHAPTYTIPLSPVLSPTLPAEAPTAQVP----PSLPRNSTMMQAVKTTPRQRSPLLNQ 358
           N    P +    S V++PTL A   T Q+P    PS     T +  V   P+  + + ++
Sbjct: 86  NPHQPPKHPDKNSSVVNPTLVA---TTQIPSVTFPSASTKITTLPNVTFLPQNATTISSR 142

Query: 359 PVPELSHASLIANQSPFRAPLNVTNTAGTSLPSVDLLQKLRLTPQHDQIQTQPLGKGAMV 418
               ++ +S +A  +P  +P     TA    PS         TP        P       
Sbjct: 143 E--NVNTSSSVATLAPVNSPAPQDTTAAPPTPSAT-------TPAPPSSSAPP---ETTA 190

Query: 419 ASFSPAAGQLATPESFIEPPSKTAAARVAASASLSNMVLAPLQSMQQNQDPEVFVQPKVL 478
           A  +P+A   A P S   P +  A     A+        AP ++      P       + 
Sbjct: 191 APPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLS 250

Query: 479 SSAIQVAGA--PLVTATTTAVSSVLLAPSVFQQTVTRSSDLERKASSPSP 526
           SSA     A  P  +ATT   SS    P       T S+      SSP+P
Sbjct: 251 SSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPAP 300



 Score = 35.4 bits (80), Expect = 0.15
 Identities = 38/141 (26%), Positives = 47/141 (33%), Gaps = 27/141 (19%)

Query: 246 PGDASQKEPNSFLPFPFEQLGGAPQSETLGVPSAAHHSVQPEIT----TPVLITPASITQ 301
           P   +Q  P+S  P    +   AP +     P+    S  PE T    TP   TPA ++ 
Sbjct: 195 PSATTQAPPSSSAP---PETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSS 251

Query: 302 SNEKHAPTYTIPLSPVLSPTL----------------PAEAPTAQVPPSLPRNSTMMQAV 345
           S    AP  T  + P  S T                 P  + T   PPS P       A 
Sbjct: 252 S----APPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPAPQETTAAP 307

Query: 346 KTTPRQRSPLLNQPVPELSHA 366
            TTP      L     E S A
Sbjct: 308 ITTPNSSPTTLAPDTSETSAA 328


>gi|222418645 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 58/231 (25%), Positives = 87/231 (37%), Gaps = 25/231 (10%)

Query: 175 DSNISSPGLQPSTQLSNL----GSTE--TLEEMPSGSQDKSAPSGHKHLTVEELFGTSLP 228
           +S++ +P L  +TQ+ ++     ST+  TL  +    Q+ +  S  +++       T  P
Sbjct: 97  NSSVVNPTLVATTQIPSVTFPSASTKITTLPNVTFLPQNATTISSRENVNTSSSVATLAP 156

Query: 229 KEQPAVVGLDSEEMERLPGDASQKEPNSFLPFPFEQLGGAPQSETLGVPSAAHHSVQPEI 288
              PA    D+      P   +   P+S  P         P + T   PS+   S  PE 
Sbjct: 157 VNSPAPQ--DTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSS---SAPPET 211

Query: 289 TTPVLITPASITQSNEKHAPTYTIPLSPVLSPTLPA----EAP--TAQVPPSLPRN---- 338
           T      PA+        AP  T    P  S T PA     AP  T  VPP+        
Sbjct: 212 TAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTAVPPTPSATTLDP 271

Query: 339 STMMQAVKTTPRQRSPLLNQPVPELSHASLIANQSPFRAPLNVTNTAGTSL 389
           S+     +TT    +P    P P  S A     Q    AP+   N++ T+L
Sbjct: 272 SSASAPPETTAAPPTPSATTPAPPSSPAP----QETTAAPITTPNSSPTTL 318



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 56/230 (24%), Positives = 82/230 (35%), Gaps = 21/230 (9%)

Query: 303 NEKHAPTYTIPLSPVLSPTLPAEAPTAQVP----PSLPRNSTMMQAVKTTPRQRSPLLNQ 358
           N    P +    S V++PTL A   T Q+P    PS     T +  V   P+  + + ++
Sbjct: 86  NPHQPPKHPDKNSSVVNPTLVA---TTQIPSVTFPSASTKITTLPNVTFLPQNATTISSR 142

Query: 359 PVPELSHASLIANQSPFRAPLNVTNTAGTSLPSVDLLQKLRLTPQHDQIQTQPLGKGAMV 418
               ++ +S +A  +P  +P     TA    PS         TP        P       
Sbjct: 143 E--NVNTSSSVATLAPVNSPAPQDTTAAPPTPSAT-------TPAPPSSSAPP---ETTA 190

Query: 419 ASFSPAAGQLATPESFIEPPSKTAAARVAASASLSNMVLAPLQSMQQNQDPEVFVQPKVL 478
           A  +P+A   A P S   P +  A     A+        AP ++      P       + 
Sbjct: 191 APPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLS 250

Query: 479 SSAIQVAGA--PLVTATTTAVSSVLLAPSVFQQTVTRSSDLERKASSPSP 526
           SSA     A  P  +ATT   SS    P       T S+      SSP+P
Sbjct: 251 SSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPAP 300



 Score = 35.4 bits (80), Expect = 0.15
 Identities = 38/141 (26%), Positives = 47/141 (33%), Gaps = 27/141 (19%)

Query: 246 PGDASQKEPNSFLPFPFEQLGGAPQSETLGVPSAAHHSVQPEIT----TPVLITPASITQ 301
           P   +Q  P+S  P    +   AP +     P+    S  PE T    TP   TPA ++ 
Sbjct: 195 PSATTQAPPSSSAP---PETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSS 251

Query: 302 SNEKHAPTYTIPLSPVLSPTL----------------PAEAPTAQVPPSLPRNSTMMQAV 345
           S    AP  T  + P  S T                 P  + T   PPS P       A 
Sbjct: 252 S----APPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPAPQETTAAP 307

Query: 346 KTTPRQRSPLLNQPVPELSHA 366
            TTP      L     E S A
Sbjct: 308 ITTPNSSPTTLAPDTSETSAA 328


>gi|167736355 mucin 4 isoform a [Homo sapiens]
          Length = 5284

 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 63/266 (23%), Positives = 97/266 (36%), Gaps = 39/266 (14%)

Query: 142  SPSQANGCSDHRPIDILEMLSRAKDEYERNQMGDSNISSPGLQPSTQLSNLGSTETLEEM 201
            SPS A+      P+ + +  S +  +     +  S+ +S G      +++  S  T +  
Sbjct: 2341 SPSSAS-TGHATPLHVTDASSVSTGDTTPLPVTSSSSASSGHTTPLPVTDASSASTGDTT 2399

Query: 202  PSGSQD-KSAPSGHKHLTVEELFGTSLPKEQPAVVGLDSE---EMERLP-GDASQKEPNS 256
            P    D  SA +GH          T LP     V GL S    +  RLP  + S      
Sbjct: 2400 PLPVTDTSSASTGH---------ATHLP-----VTGLSSASTGDTTRLPVTNVSSASTGH 2445

Query: 257  FLPFPFEQLGGAPQSETLGVPSAAHHSVQPEITTPVLITPASITQSNEKHAPTYTIPLSP 316
              P P      A   +T  +P     SV    TTP+L+T AS   + +      T P S 
Sbjct: 2446 ATPLPVTSTSSASTGDTTPLPGTDTSSVSTGHTTPLLVTDASSVSTGDTTRLPVTSPSSA 2505

Query: 317  VLSPTLP---AEAPTAQVPPSLP-----------RNSTMMQAVKTTPRQRSPLLNQPVPE 362
                T P    + P+A    + P           R++T +     +        + PV +
Sbjct: 2506 STGHTTPLPVTDTPSASTGDTTPLPVTNASSLSTRHATSLHVTSPSSASTGHATSLPVTD 2565

Query: 363  LSHASLIANQSPFRAPLNVTNTAGTS 388
             S AS     +    PL VT+T+  S
Sbjct: 2566 TSAAS-----TGHATPLPVTSTSSAS 2586



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 86/399 (21%), Positives = 137/399 (34%), Gaps = 38/399 (9%)

Query: 154  PIDILEMLSRAKDEYERNQMGDSNISSPGLQPSTQLSNLGSTETLEEMPSGSQD-KSAPS 212
            P+ +  + S +  +     + D++ +S G   S  +++  S  T    P    D  SA +
Sbjct: 1072 PLPVTSLSSASTGDTTPLPVTDTSSASTGHATSLPVTDTSSVSTGHTTPLPVTDTSSAST 1131

Query: 213  GHKHLTVEELFGTSLPKEQPAVVGLDSEEMERLPGDASQKEPNSFLPFPFEQLGGAPQSE 272
            GH          TSLP    + V         +  DAS        P P   L      +
Sbjct: 1132 GH---------ATSLPVTDTSSVSTGHTTPLHVT-DASSASTGQATPLPVTSLSSVSTGD 1181

Query: 273  TLGVPSAAHHSVQPEITTPVLITPASITQSNE------KHAPTYTIPLSPVLSPTLPAEA 326
            T  +P  +  S      TP+L+T  S   +          A + +   +  L  T+P+ A
Sbjct: 1182 TTPLPVTSPSSASTGHATPLLVTDTSSASTGHATPLPVTDASSVSTDHATSLPVTIPSAA 1241

Query: 327  PTAQVPPSLPRNSTMM----QAVKTTPRQRSPLLNQPVPELSHASLIANQSPFRAPLNVT 382
             T    P LP   T      QA        S +       L   S  +  +    PL+VT
Sbjct: 1242 STGHTTP-LPVTDTSSASTGQATSLLVTDTSSVSTGDTTPLPVTSTSSASTGHVTPLHVT 1300

Query: 383  NTAGTSLPSVDLLQKLRLTPQHDQIQTQPLGKGAMVASFSPAAGQLATPESFIEPPSKTA 442
            + +  S      L    L+       T PL     V S S A+    TP    +  S + 
Sbjct: 1301 SPSSASTGHATPLPVTSLSSASTG-DTMPL----PVTSPSSASTGDTTPLPVTDASSVST 1355

Query: 443  AARV------AASASLSNMVLAPLQSMQQNQDPEVFVQPKVLSSAIQVAGA-PLVTATTT 495
                      A+SAS       P+ S+      +    P    S+     A PL+   T+
Sbjct: 1356 GHTTPLHVTDASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDTS 1415

Query: 496  AVSSVLLAPSVFQQTVTRSSDLERKASSPSPLTIGTPES 534
            + S+    P      VT +S +    ++  P+TI +  S
Sbjct: 1416 SASTGHATP----LPVTDASSVSTDHATSLPVTIPSAAS 1450



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 74/323 (22%), Positives = 115/323 (35%), Gaps = 40/323 (12%)

Query: 259  PFPFEQLGGAPQSETLGVPSAAHHSVQPEITTPVLITPASITQSNEKHAPTYTIPLSPVL 318
            P P   L  A   +T+ +P  +  S     TTP+ +T AS   +       +T PL PV 
Sbjct: 1520 PLPVTSLSSASTGDTMPLPVTSPSSASTGDTTPLPVTDASSVSTG------HTTPL-PVT 1572

Query: 319  SPTLPAEAPTAQVP----PSLPRNSTMMQAVKTTPRQRSPLLNQPVPELSHASLIANQSP 374
            SP+  +   T  +P     S  +  T    V T+P   S     P+P    +S     + 
Sbjct: 1573 SPSSASTGHTTPLPVTDTSSASKGDTTPLPV-TSPSSASTGHTTPLPVTDTSSASTGDT- 1630

Query: 375  FRAPLNVTNTAGTSLPSVDLLQKLRLTPQHDQIQTQPLGKGAMVASFSPAAGQLATPESF 434
               PL VTN +  S            TP H    T P       A+  P     +     
Sbjct: 1631 --TPLPVTNASSLSTG--------HATPLH---VTSPSSASTGHATPLPVTSTSSASTGH 1677

Query: 435  IEPPSKTAAARVAASASLSNMVLAPLQSMQQNQDPEVFVQPKVLSSAIQVAG-APLVTAT 493
              P   T      +SA+  +    P+  +      +    P    S++      PL   +
Sbjct: 1678 ATPLPVTG----LSSATTDDTTRLPVTDVSSASTGQATPLPVTSLSSVSTGDTTPLPVTS 1733

Query: 494  TTAVSSVLLAPSVFQQTVTRSSDLERKASSPSPLT----IGTPESQRKPSIILSKSQLQD 549
             ++ S+   +P +    VT +S      ++P P+T    + T  +   P   LS +   D
Sbjct: 1734 PSSASTGHASPLL----VTDASSASTGQATPLPVTDTSSVSTAHATPLPVTGLSSASTDD 1789

Query: 550  TLIHLIKNDSSFLSTLHEVYLQV 572
            T   L   D S  ST   + L V
Sbjct: 1790 T-TRLPVTDVSSASTGQAIPLPV 1811



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 90/411 (21%), Positives = 144/411 (35%), Gaps = 41/411 (9%)

Query: 175  DSNISSPGLQPSTQLSNLGSTETLEEMPSGSQDKSAPSGHKH--LTVEELFGTSLPKEQP 232
            D++  S G      +++L S  T +  P    D S+ S  +   L V  L   S     P
Sbjct: 3397 DTSSVSTGHATPLPVTSLSSVSTGDTTPLPVTDASSASTGQATPLPVTSLSSVSTGDTTP 3456

Query: 233  AVV----GLDSEEMERLP-GDASQKEPNSFLPFPFEQLGGAPQSETLGVPSAAHHSVQPE 287
             +V     + +     LP  D S          P      A   +   +P  +  SV   
Sbjct: 3457 LLVTDASSVSTGHATPLPVTDTSSASTGDTTRLPVTDTSSASTGQATPLPVTSLSSVSTG 3516

Query: 288  ITTPVLITPASITQSNEKHAPTYTIPLSPVLSPTLPAEAPTAQVPPSLPRNSTMMQAVK- 346
             TTP+L+T AS   +       +  PL PV   +  +   T ++P +   +++  QA   
Sbjct: 3517 DTTPLLVTDASSVSTG------HATPL-PVTDTSSASTGDTTRLPVTDTSSASTGQATPL 3569

Query: 347  --TTPRQRSPLLNQPVPELSHASLIANQSPFRAPLNVTNTAGTSLPSVDLLQKLRLTPQH 404
              T P   S     P+P  S +S+         PL+VT+ +  S   V  L  +  T   
Sbjct: 3570 PVTIPSSSSSGHTTPLPVTSTSSVSTGHV---TPLHVTSPSSASTGHVTPL-PVTSTSSA 3625

Query: 405  DQIQTQPLGKGAMVASFSPAAGQLATPESFIEPPSKTAAARVAASASLSNMVLAPLQSMQ 464
                  PL    +V   S  +   ATP    +          A+SAS  +    P+    
Sbjct: 3626 STGHATPL----LVTDASSVSTGHATPLPVTD----------ASSASTGDTTPLPVTDTS 3671

Query: 465  QNQDPEVFVQPKVLSSAIQVAGA---PLVTATTTAVSSVLLAPSVFQQTVTRSSDLERKA 521
                 +    P    S++        P+  A++ +       P     +V+    +    
Sbjct: 3672 SASTGQATPLPVTSLSSVSTGDTTPLPVTDASSASTGHATPLPVTIPSSVSTGDTMPLPV 3731

Query: 522  SSPSPLTIGTPESQRKPSIILSKSQLQDTLIHLIKNDSSFLSTLHEVYLQV 572
            +SPS  + G   +   P   LS +   DT   L   D+S  ST H   L V
Sbjct: 3732 TSPSSASTG--HATPLPVTGLSSASTGDT-TPLPVTDTSSASTRHATPLPV 3779



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 74/325 (22%), Positives = 108/325 (33%), Gaps = 38/325 (11%)

Query: 248  DASQKEPNSFLPFPFEQLGGAPQSETLGVPSAAHHSVQPEITTPVLITPASITQSNEKHA 307
            DAS        P P      A   +   +P  +  SV    TTP+ +T AS   +     
Sbjct: 3653 DASSASTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTDASSASTGHATP 3712

Query: 308  PTYTIPLSPVLSPTLPAEAPTAQVPPSLPRNSTMMQAVKTTPRQRSPLLNQPVPELSHAS 367
               TIP S     T+P   P      +   ++T +     +          PV + S AS
Sbjct: 3713 LPVTIPSSVSTGDTMPL--PVTSPSSASTGHATPLPVTGLSSASTGDTTPLPVTDTSSAS 3770

Query: 368  LIANQSPFRAPLNVTNTAGTSLPSVDLLQKLRLTPQHDQIQTQPLGKGAMVASFSPAAGQ 427
                 +    PL VT+T+  S      L                      V   S A+  
Sbjct: 3771 -----TRHATPLPVTDTSSASTDDTTRLP---------------------VTDVSSASTG 3804

Query: 428  LATPESFIEPPSKTAAARVAASASLSNMVLAPLQSMQQNQDPEVFVQPKVLSSAIQVAGA 487
             ATP     P + T++A    +  L    +    S+       + V  +  SSA      
Sbjct: 3805 HATPL----PVTSTSSASTGDTTPLP---VTDTSSVSTGHATSLPVTSR--SSASTGHAT 3855

Query: 488  PLVTATTTAVSSVLLAPSVFQQTVTRSSDLERKASSPSPLTIGTPESQRKPSIILSKSQL 547
            PL    T++VS+    P     T + S+         SP +  T  +   P    S +  
Sbjct: 3856 PLPVTDTSSVSTGHATPLPVTSTSSVSTGHATPLPVTSPSSASTGHATPVPVTSTSSAST 3915

Query: 548  QDTLIHLIKNDSSFLSTLHEVYLQV 572
             DT    + N SS LST H   L V
Sbjct: 3916 GDTTPLPVTNASS-LSTGHATPLHV 3939



 Score = 37.7 bits (86), Expect = 0.029
 Identities = 59/266 (22%), Positives = 98/266 (36%), Gaps = 24/266 (9%)

Query: 151  DHRPIDILEMLSRAKDEYERNQMGDSNISSPGLQPSTQLSNLGSTETLEEMPSG-SQDKS 209
            D  P+ +    S +        + D++ +S G      ++N  S  T    P   +   S
Sbjct: 1597 DTTPLPVTSPSSASTGHTTPLPVTDTSSASTGDTTPLPVTNASSLSTGHATPLHVTSPSS 1656

Query: 210  APSGHKH-LTVEELFGTSLPKEQPA-VVGLDS---EEMERLP-GDASQKEPNSFLPFPFE 263
            A +GH   L V      S     P  V GL S   ++  RLP  D S        P P  
Sbjct: 1657 ASTGHATPLPVTSTSSASTGHATPLPVTGLSSATTDDTTRLPVTDVSSASTGQATPLPVT 1716

Query: 264  QLGGAPQSETLGVPSAAHHSVQPEITTPVLITPASITQSNE----------KHAPTYTIP 313
             L      +T  +P  +  S      +P+L+T AS   + +            +  +  P
Sbjct: 1717 SLSSVSTGDTTPLPVTSPSSASTGHASPLLVTDASSASTGQATPLPVTDTSSVSTAHATP 1776

Query: 314  LSPVLSPTLPAEAPTAQVPPSLPRNSTMMQAVK---TTPRQRSPLLNQPVPELSHASLIA 370
            L PV   +  +   T ++P +   +++  QA+    T+P   S     P+P    +S   
Sbjct: 1777 L-PVTGLSSASTDDTTRLPVTDVSSASTGQAIPLPVTSPSSASTGDTTPLPVTDASSAST 1835

Query: 371  NQS---PFRAPLNVTNTAGTSLPSVD 393
              +   P   P + ++   TSLP  D
Sbjct: 1836 GDTTSLPVTIPSSASSGHTTSLPVTD 1861



 Score = 36.6 bits (83), Expect = 0.065
 Identities = 84/376 (22%), Positives = 133/376 (35%), Gaps = 46/376 (12%)

Query: 175  DSNISSPGLQPSTQLSNLGSTETLEEMPSG-SQDKSAPSGHKH-LTVEELFGTSLPKEQP 232
            D++ +S G      +++L S  T +  P   +   SA +GH   L V +    S  +   
Sbjct: 2949 DTSSASTGHATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHTTPLPVTDTSSASTGQATA 3008

Query: 233  AVVGLDSE----EMERLP-GDASQKEPNSFLPFPFEQLGGAPQSETLGVPSAAHHSVQPE 287
              V   S     +   LP  D S        P P   L      +T  +P  +  S    
Sbjct: 3009 LPVTSTSSASTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTG 3068

Query: 288  ITTPVLITPASITQSNEKHAPTYTIPLSPVLSPTLPAEAPTAQVPPSLPR-----NSTMM 342
              TP+L+T AS   + +        PL PV S +  +   T  +P + P      ++T +
Sbjct: 3069 HATPLLVTDASSASTGQ------ATPL-PVTSLSSVSTGDTTPLPVTSPSSASTGHATSL 3121

Query: 343  QAVKTTPRQRSPLLNQPVPELSHASLIANQSPFRAPLNVTNTAGTSLPSVDLLQKLRLTP 402
                T+        + PV + S A      S     L VT+T+ +S      L    L  
Sbjct: 3122 PVTDTSSASTGDTTSLPVTDTSSAYTGDTTS-----LPVTDTSSSSTGDTTPL----LVT 3172

Query: 403  QHDQIQT---QPLGKGAMVASFSPAAGQLATPESFIEPPSKTAAARV------AASASLS 453
            +   + T    PL    +V   S A+   ATP     P S +            +S S  
Sbjct: 3173 ETSSVSTGHATPL----LVTDASSASTGHATPLHVTSPSSASTGDTTPVPVTDTSSVSTG 3228

Query: 454  NMVLAPLQSMQQNQDPEVFVQPKV-LSSAIQVAGAPLVTATTTAVSSVLLAPSVFQQTVT 512
            +    P+  +      +    P   +SSA      PL    T++VS+    P      VT
Sbjct: 3229 HATPLPVTGLSSASTGDTTRLPVTDISSASTGQATPLPVTNTSSVSTGDTMP----LPVT 3284

Query: 513  RSSDLERKASSPSPLT 528
              S      ++P P+T
Sbjct: 3285 SPSSASTGHATPLPVT 3300



 Score = 36.2 bits (82), Expect = 0.085
 Identities = 59/237 (24%), Positives = 86/237 (36%), Gaps = 30/237 (12%)

Query: 175  DSNISSPGLQPSTQLSNLGSTETLEEMPSGSQDKSAPS-GHK-HLTVEELFGTSLPKEQP 232
            D++ +S G      +++L S  T +  P    D S+ S GH   L V  L   S     P
Sbjct: 2229 DTSSASTGQATPLPVTSLSSASTGDTTPLPVTDASSVSTGHATSLPVTSLSSVSTGDTTP 2288

Query: 233  AVVGLDSEEM--ERLP---GDASQKEPNSFLPFPFEQLGGAPQSETLGVPSAAHHSVQPE 287
              V   S        P    DAS        P P   L  A   +T  +P  +  S    
Sbjct: 2289 LPVTSPSSASTGHATPLHVTDASSASTGHATPLPVTSLSSASTGDTTPLPVTSPSSASTG 2348

Query: 288  ITTPVLITPASITQSNEKHAPTYTIPLSPVLSPTLPAEAPTAQVP-----PSLPRNSTMM 342
              TP+ +T AS   + +      T PL PV S +  +   T  +P      +   ++T +
Sbjct: 2349 HATPLHVTDASSVSTGD------TTPL-PVTSSSSASSGHTTPLPVTDASSASTGDTTPL 2401

Query: 343  QAVKTTPRQRSPLLNQPVPELSHASL-------IANQSP----FRAPLNVTNTAGTS 388
                T+        + PV  LS AS        + N S        PL VT+T+  S
Sbjct: 2402 PVTDTSSASTGHATHLPVTGLSSASTGDTTRLPVTNVSSASTGHATPLPVTSTSSAS 2458



 Score = 34.7 bits (78), Expect = 0.25
 Identities = 82/346 (23%), Positives = 123/346 (35%), Gaps = 46/346 (13%)

Query: 175  DSNISSPGLQPSTQLSNLGSTETLEEMPSG-SQDKSAPSGHK---HLTVEELFGTSLPKE 230
            D++ +S G   S  +++  S  T +  P   +   SA +GH    H+T      T     
Sbjct: 1461 DTSSASTGQATSLLVTDTSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSASTGHATP 1520

Query: 231  QPAVVGLDSEEMERLPGDASQKEPNSFLPFPFEQLGGAPQSETLGVPSAAHHSVQPEITT 290
             P V  L S       GD         +P P      A   +T  +P     SV    TT
Sbjct: 1521 LP-VTSLSSAST----GDT--------MPLPVTSPSSASTGDTTPLPVTDASSVSTGHTT 1567

Query: 291  PVLIT-PASITQSNEKHAP-TYTIPLS----PVLSPTLPAEAPTAQVPPSLPRNSTMMQA 344
            P+ +T P+S +  +    P T T   S      L  T P+ A T    P    +++    
Sbjct: 1568 PLPVTSPSSASTGHTTPLPVTDTSSASKGDTTPLPVTSPSSASTGHTTPLPVTDTSSAST 1627

Query: 345  VKTTPRQRSPLLNQPVPELSHASLIANQSPFRA------PLNVTNTAGTSLPSVDLLQKL 398
              TTP    P+ N       HA+ +   SP  A      PL VT+T+  S      L   
Sbjct: 1628 GDTTP---LPVTNASSLSTGHATPLHVTSPSSASTGHATPLPVTSTSSASTGHATPLPVT 1684

Query: 399  RLTPQHDQIQTQPLGKGAMVASFSPAAGQLATPESFIEPPSKTAAARVAASASLSNMVLA 458
             L+       T+       V   S A+   ATP         T+ + V+   +    V +
Sbjct: 1685 GLSSATTDDTTR-----LPVTDVSSASTGQATPLPV------TSLSSVSTGDTTPLPVTS 1733

Query: 459  PLQSMQQNQDPEVFVQPKVLSSAIQVAGAPLVTATTTAVSSVLLAP 504
            P  +   +  P +       SSA      PL    T++VS+    P
Sbjct: 1734 PSSASTGHASPLLVTD---ASSASTGQATPLPVTDTSSVSTAHATP 1776



 Score = 34.3 bits (77), Expect = 0.32
 Identities = 100/443 (22%), Positives = 154/443 (34%), Gaps = 41/443 (9%)

Query: 151  DHRPIDILEMLSRAKDEYERNQMGDSNISSPGLQPSTQLSNLGSTETLEEMPSGSQDKSA 210
            D  P+ +    S +        + D++    G   S  +++  S  T    P    D S+
Sbjct: 1933 DTTPLPVTSPSSASSGHTTPLPVTDASSVPTGHATSLPVTDASSVSTGHATPLPVTDASS 1992

Query: 211  PS-GHKH-LTVEELFGTSLPKEQPAVV----GLDSEEMERLP-GDASQKEPNSFLPFPFE 263
             S GH   L V +    S  +  P  V       + +   LP  D S        P P  
Sbjct: 1993 VSTGHATPLPVTDTSSVSTGQATPLPVTSLSSASTGDTTPLPVTDTSSASTGQDTPLPVT 2052

Query: 264  QLGGAPQSETLGVPSAAHHSVQPEITTPVLITPASITQSNEKHAPTYTIPLSPVLSPTLP 323
             L      +T  +P  +  S      TP+L+T AS   +   HA +  +  +  +S T  
Sbjct: 2053 SLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDASSVSTG--HATSLLVTDASSVS-TGH 2109

Query: 324  AEAPTAQVPPSLPRNSTMMQAVKTTPRQRSPLLNQPVPELSHASLIANQSPFRAPLNVTN 383
            A A       SL    T    V T+P   S     P+P ++  S ++       P+  T+
Sbjct: 2110 ATALHVTDASSLSTGDTTPLPV-TSPSSASTGDTTPLP-VTDTSSVSTGHATSLPVTDTS 2167

Query: 384  TA----GTSLPSVDLLQKLRLTPQHDQIQTQPLGKGAMVASFSPAAGQLATPESFIEPPS 439
            +A     TSLP  D       T         PL     V   S A+   ATP     P S
Sbjct: 2168 SASTGHATSLPVTD-------TSSASTGHATPL----PVTDTSSASTGQATPLPVTSPSS 2216

Query: 440  KTAAARV------AASASLSNMVLAPLQSMQQNQDPEVFVQPKVLSSAIQVAGAPLVTAT 493
             +    +       +SAS       P+ S+      +    P  ++ A  V+     +  
Sbjct: 2217 ASTGHAIPLLVTDTSSASTGQATPLPVTSLSSASTGD--TTPLPVTDASSVSTGHATSLP 2274

Query: 494  TTAVSSVLLAPSVFQQTVTRSSDLERKASSPSPLT----IGTPESQRKPSIILSKSQLQD 549
             T++SSV    +     VT  S      ++P  +T      T  +   P   LS +   D
Sbjct: 2275 VTSLSSVSTGDTT-PLPVTSPSSASTGHATPLHVTDASSASTGHATPLPVTSLSSASTGD 2333

Query: 550  TLIHLIKNDSSFLSTLHEVYLQV 572
            T    + + SS  ST H   L V
Sbjct: 2334 TTPLPVTSPSS-ASTGHATPLHV 2355



 Score = 32.7 bits (73), Expect = 0.94
 Identities = 76/383 (19%), Positives = 130/383 (33%), Gaps = 34/383 (8%)

Query: 154  PIDILEMLSRAKDEYERNQMGDSNISSPGLQPSTQLSNLGSTETLEEMPSGSQDKSAPSG 213
            P+ +  + S + D+  R  + D + +S G      +++  S  T +  P    D S+ S 
Sbjct: 1776 PLPVTGLSSASTDDTTRLPVTDVSSASTGQAIPLPVTSPSSASTGDTTPLPVTDASSAST 1835

Query: 214  HKHLTVEELFG--------TSLPKEQPAVVGLDSEEMERLPGDASQKEPNSFLPFPFEQL 265
                ++             TSLP    + V         L  DAS        P P    
Sbjct: 1836 GDTTSLPVTIPSSASSGHTTSLPVTDASSVST-GHATSLLVTDASSVSTGDTTPLPVTDT 1894

Query: 266  GGAPQSETLGVPSAAHHSVQPEITTPVLITPASITQSNEKHAPTYTIPLSPVLSPTLPAE 325
              A   +T  +      SV     T + +T  S   + +      T PL PV SP+  + 
Sbjct: 1895 NSASTGDTTPLHVTDASSVSTGHATSLPVTSLSSASTGD------TTPL-PVTSPSSASS 1947

Query: 326  APTAQVPPSLPRNSTMMQAVKTTPRQRSPLLNQPVPELSHASLIANQSPFRAPLNVTNTA 385
              T  +P       T   +V T      P+ +       HA+ +    P     +V+   
Sbjct: 1948 GHTTPLP------VTDASSVPTGHATSLPVTDASSVSTGHATPL----PVTDASSVSTGH 1997

Query: 386  GTSLPSVDLLQKLRLTPQHDQIQTQPLGKGAMVASFSPAAGQLATPESFIEPPSKTAAAR 445
             T LP  D       T      Q  PL   ++ ++ +     L   ++      +     
Sbjct: 1998 ATPLPVTD-------TSSVSTGQATPLPVTSLSSASTGDTTPLPVTDTSSASTGQDTPLP 2050

Query: 446  VAASASLSNMVLAPLQSMQQNQDPEVFVQPKVLSSAIQVAGAPLVTATTTAVSSVLLAPS 505
            V + +S+S     PL     +        P +++ A  V+     +   T  SSV    +
Sbjct: 2051 VTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDASSVSTGHATSLLVTDASSVSTGHA 2110

Query: 506  VFQQTVTRSSDLERKASSPSPLT 528
                 VT +S L    ++P P+T
Sbjct: 2111 TALH-VTDASSLSTGDTTPLPVT 2132



 Score = 32.0 bits (71), Expect = 1.6
 Identities = 86/406 (21%), Positives = 139/406 (34%), Gaps = 44/406 (10%)

Query: 144  SQANGCSDHRPIDILEMLSRAKDEYERNQMGDSNISSPGLQPSTQLSNLGSTETLEEMPS 203
            + ++   D  P+ + E  S +        + D++ +S G      +++  S  T +  P 
Sbjct: 3158 TSSSSTGDTTPLLVTETSSVSTGHATPLLVTDASSASTGHATPLHVTSPSSASTGDTTPV 3217

Query: 204  GSQDKSAPS-GHKHLTVEELFGTSLPKEQPAVVGLDSE---EMERLP-GDASQKEPNSFL 258
               D S+ S GH          T LP     V GL S    +  RLP  D S        
Sbjct: 3218 PVTDTSSVSTGH---------ATPLP-----VTGLSSASTGDTTRLPVTDISSASTGQAT 3263

Query: 259  PFPFEQLGGAPQSETLGVPSAAHHSVQPEITTPVLI-----------TPASITQSNEKHA 307
            P P          +T+ +P  +  S      TP+ +           TP  +T S    +
Sbjct: 3264 PLPVTNTSSVSTGDTMPLPVTSPSSASTGHATPLPVTSTSSASTGHATPVPVT-STSSAS 3322

Query: 308  PTYTIPLSPVLSPTLPAEAPTAQVPPSLPRNSTMMQAVK---TTPRQRSPLLNQPVPELS 364
              +T PL PV   +  +   T  +P + P +++         T P   S      +P   
Sbjct: 3323 TGHTTPL-PVTDTSSASTGDTTPLPVTSPSSASTGHTTPLHVTIPSSASTGDTSTLPVTG 3381

Query: 365  HASLIANQSPFRAPLNVTNTAGTSLPSVDLLQKLRLTPQHDQIQTQPLGKGAMVASFSPA 424
             +S     +    PL VT+T+  S      L    L+       T      A  AS   A
Sbjct: 3382 ASSASTGHA---TPLPVTDTSSVSTGHATPLPVTSLSSVSTGDTTPLPVTDASSASTGQA 3438

Query: 425  AGQLATPESFIEPPSKT-AAARVAASASLSNMVLAPLQSMQQNQDPEVFVQPKV-LSSAI 482
                 T  S +     T      A+S S  +    P+         +    P    SSA 
Sbjct: 3439 TPLPVTSLSSVSTGDTTPLLVTDASSVSTGHATPLPVTDTSSASTGDTTRLPVTDTSSAS 3498

Query: 483  QVAGAPLVTATTTAVSSVLLAPSVFQQTVTRSSDLERKASSPSPLT 528
                 PL   + ++VS+    P +    VT +S +    ++P P+T
Sbjct: 3499 TGQATPLPVTSLSSVSTGDTTPLL----VTDASSVSTGHATPLPVT 3540



 Score = 32.0 bits (71), Expect = 1.6
 Identities = 32/141 (22%), Positives = 45/141 (31%), Gaps = 7/141 (4%)

Query: 248  DASQKEPNSFLPFPFEQLGGAPQSETLGVPSAAHHSVQPEITTPVLITPASITQSNEKHA 307
            DAS        P P   L      +T  +P     S      TP+ +T  S   + +   
Sbjct: 3957 DASSASTGHATPLPLTSLSSVSTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTP 4016

Query: 308  PTYTIPLSPVLSPTLPAEAPTAQVPPSLPRNSTMMQAVKTTPRQRSPLLNQPVPELSHAS 367
               TIP S     T     P          + T +    T+          PV + S AS
Sbjct: 4017 LPVTIPSSASSGHT--TSLPVTDASSVSTGHGTPLPVTSTSSASTGDTTPLPVTDTSSAS 4074

Query: 368  LIANQSPFRAPLNVTNTAGTS 388
                 +    PL VT+T+  S
Sbjct: 4075 -----TGHATPLPVTDTSSAS 4090



 Score = 29.6 bits (65), Expect = 8.0
 Identities = 54/281 (19%), Positives = 97/281 (34%), Gaps = 31/281 (11%)

Query: 259  PFPFEQLGGAPQSETLGVPSAAHHSVQPEITTPVLITPASITQSNEKHAPTYTIPLSPVL 318
            P P      A   +   +P  +  SV    TTP+ +T  S   ++  HA +  +  +   
Sbjct: 2784 PLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTDTS--SASTGHATSLPVTDTSSA 2841

Query: 319  SPTLPAEAPTAQVPPSLPRNSTMMQAVKTTPRQRSPLLNQPVPELS-----HASLIANQS 373
            S       P      +   ++T++    T+        + PV + S     HA+ +   S
Sbjct: 2842 STGHATPLPDTDTSSASTGHATLLPVTDTSSASIGHATSLPVTDTSSISTGHATPLHVTS 2901

Query: 374  PFRA------PLNVTNTAGTSLPSVDLLQKLRLTPQHDQIQTQPLGKGAMVASFSPAAGQ 427
            P  A      PL VT+T+  S    +        P H    T P       A+  P    
Sbjct: 2902 PSSASTGHATPLPVTDTSSASTGHAN--------PLH---VTSPSSASTGHATPLPVTDT 2950

Query: 428  LATPESFIEPPSKTAAARVAASASLSNMVLAPLQSMQQNQDPEVFVQPKVLSSAIQVAGA 487
             +       P   T+ + V+   +    V +P  +   +  P + V     +S  Q    
Sbjct: 2951 SSASTGHATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHTTP-LPVTDTSSASTGQATAL 3009

Query: 488  PLVTATTTAVSSVLLAPSVFQQTVTRSSDLERKASSPSPLT 528
            P+ + ++ +       P      VT +S      ++P P+T
Sbjct: 3010 PVTSTSSASTGDTTPLP------VTDTSSASTGQATPLPVT 3044


>gi|194733742 Wolf-Hirschhorn syndrome candidate 2 protein [Homo
           sapiens]
          Length = 539

 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 75/294 (25%), Positives = 105/294 (35%), Gaps = 43/294 (14%)

Query: 119 AKLMADVVEEETRRSQQAARDKQSPSQANGCSDHRPIDILEMLSRA-KDEYERNQMGDSN 177
           A L A+++++ T  +QQ  R    P  A G    R +D    L    K    R+    S 
Sbjct: 183 ATLRAELLQKSTETAQQLKRSAGVPFHAKGRGLLRKMDTTTPLKGIPKQAPFRSPTAPSV 242

Query: 178 ISSPG----LQPS-TQLSNLGSTETLE--EMPSGSQDKSAPSGHKHLTVEELFGTSLPKE 230
            S  G    + PS T L      + L+  E+      + A    K L  E +     P +
Sbjct: 243 FSPTGNRTPIPPSRTLLRKERGVKLLDISELDMVGAGREAKRRRKTLDAEVV---EKPAK 299

Query: 231 QPAVV---------GLDSEEMERLPGDASQKEPNSFLPFPFEQLGGA---PQSETLGVPS 278
           +  VV         GL S +      +       S+LP     +  +   P SET   PS
Sbjct: 300 EETVVENATPDYAAGLVSTQKLGSLNNEPALPSTSYLPSTPSVVPASSYIPSSETPPAPS 359

Query: 279 AAHHSVQPEI-TTPVLITPASITQSNEKH-------APTYTIPLSPVLSPTLPAEAPTAQ 330
           +   S  PE  + P    PA   Q    +        PT   P SP+   T PA APT Q
Sbjct: 360 SREASRPPEEPSAPSPTLPAQFKQRAPMYNSGLSPATPTPAAPTSPLTPTTPPAVAPTTQ 419

Query: 331 VPPSLPRNSTMMQAVKTTPRQRSPLLNQPVPELS--HASLIANQSPFRAPLNVT 382
            PP               P+ ++P   QP   LS     + A Q  F+    VT
Sbjct: 420 TPP----------VAMVAPQTQAPAQQQPKKNLSLTREQMFAAQEMFKTANKVT 463


>gi|239751395 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 306

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 54/252 (21%), Positives = 89/252 (35%), Gaps = 18/252 (7%)

Query: 289 TTPVLITPASITQSNEKHAPTYTIPLSPVLSPTLPAEAPTAQVPPSLPRNSTMMQAVKT- 347
           ++P  +TP+S         P  T   +P L+P+ P     +  P   P N+  +    T 
Sbjct: 13  SSPPTLTPSSTPTLTPSSQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLTPSSTP 72

Query: 348 --TPRQRSPLLNQPV-PELSHASLIANQSPFRAPLNVTNTAGTSLPSVDLLQKLRLTPQH 404
             TP     L  QP+    S  +L  +  P   P N      ++ P++       LTP  
Sbjct: 73  TLTPSSTPTLTPQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLTPSNTPTLTPSS 132

Query: 405 DQIQTQPLGKGAMVASFSPAAGQLATPESFIEPPSKTAAARVAASASLSNMVLAPLQSMQ 464
               T P     +  S  P   + +TP   + P S+    R       S   L P  +  
Sbjct: 133 TPTLT-PSSTPTLTPSSRPILTRSSTPT--LTPSSRPILTR------SSTPTLTPSSTPT 183

Query: 465 QNQDPEVFVQPKVLSSAIQVAGAPLV----TATTTAVSSVLLAPSVFQQTVTRSSDLERK 520
                   + P   +  +  +  P++    T T T  S  +L PS        S  +  +
Sbjct: 184 LTPSSTPTLTPS-STPTLTPSSRPILTRSSTPTLTPSSRPILTPSSTPTLTPSSRPILTR 242

Query: 521 ASSPSPLTIGTP 532
           +S+P+     TP
Sbjct: 243 SSTPTLTPSSTP 254



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 54/234 (23%), Positives = 89/234 (38%), Gaps = 22/234 (9%)

Query: 283 SVQPEITTPVLITPASITQSNEKHAPTYTIPLSPVLSPT-----LPAEAPTAQVPPSLPR 337
           S  P +T   ++T +S         PT T   +P L+P+      P+  PT  + PS   
Sbjct: 77  SSTPTLTPQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLTPSNTPT--LTPSSTP 134

Query: 338 NSTMMQAVKTTPRQRSPLLNQPVPELSHAS---LIANQSPFRAPLNVTNTAGTSLPSVDL 394
             T       TP  R  L     P L+ +S   L  + +P   P +      +S P++  
Sbjct: 135 TLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSSTPTLTP 194

Query: 395 LQKLRLTPQHDQIQTQPLGKGAMVASFSPAAGQLATPESFIEPPSKTAAARVAASASLSN 454
                LTP      ++P+   +   + +P++  + TP S    P+ T ++R   + S S 
Sbjct: 195 SSTPTLTP-----SSRPILTRSSTPTLTPSSRPILTPSS---TPTLTPSSRPILTRS-ST 245

Query: 455 MVLAPLQSMQQNQDPEVFVQPK---VLSSAIQVAGAPLVTATTTAVSSVLLAPS 505
             L P  +          + P     L+ +      P  T T T  S+  L PS
Sbjct: 246 PTLTPSSTPTLTPSNTPTLTPSNTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPS 299



 Score = 36.2 bits (82), Expect = 0.085
 Identities = 50/227 (22%), Positives = 85/227 (37%), Gaps = 28/227 (12%)

Query: 314 LSPVLSPTLPAEAPTAQVPPSLPRNSTMMQAVKTTPRQRSPLLNQPVPELSHASLIANQS 373
           L+P  +PTL   +P    P S P  +   Q + T  R  +P L    P     +L  + +
Sbjct: 2   LTPSNTPTLTPSSPPTLTPSSTPTLTPSSQPILT--RSSTPTLTPSSP----PTLTPSNT 55

Query: 374 PFRAPLNVTNTAGTSLPSVDLLQKLRLTPQHDQIQTQPLGKGAMVASFSPAAGQLATPES 433
           P   P N      +S P++       LTP       QP+   +   + +P++    TP +
Sbjct: 56  PTLTPSNTPTLTPSSTPTLTPSSTPTLTP-------QPILTRSSTPTLTPSSPPTLTPSN 108

Query: 434 --FIEP-------PSKTAAARVAASASL---SNMVLAPLQSMQQNQDPEVFVQPK---VL 478
              + P       PS T     +++ +L   S   L P       +     + P    +L
Sbjct: 109 TPTLTPSNTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPIL 168

Query: 479 SSAIQVAGAPLVTATTTAVSSVLLAPSVFQQTVTRSSDLERKASSPS 525
           + +      P  T T T  S+  L PS        S  +  ++S+P+
Sbjct: 169 TRSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPT 215


>gi|239745904 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 306

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 54/252 (21%), Positives = 89/252 (35%), Gaps = 18/252 (7%)

Query: 289 TTPVLITPASITQSNEKHAPTYTIPLSPVLSPTLPAEAPTAQVPPSLPRNSTMMQAVKT- 347
           ++P  +TP+S         P  T   +P L+P+ P     +  P   P N+  +    T 
Sbjct: 13  SSPPTLTPSSTPTLTPSSQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLTPSSTP 72

Query: 348 --TPRQRSPLLNQPV-PELSHASLIANQSPFRAPLNVTNTAGTSLPSVDLLQKLRLTPQH 404
             TP     L  QP+    S  +L  +  P   P N      ++ P++       LTP  
Sbjct: 73  TLTPSSTPTLTPQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLTPSNTPTLTPSS 132

Query: 405 DQIQTQPLGKGAMVASFSPAAGQLATPESFIEPPSKTAAARVAASASLSNMVLAPLQSMQ 464
               T P     +  S  P   + +TP   + P S+    R       S   L P  +  
Sbjct: 133 TPTLT-PSSTPTLTPSSRPILTRSSTPT--LTPSSRPILTR------SSTPTLTPSSTPT 183

Query: 465 QNQDPEVFVQPKVLSSAIQVAGAPLV----TATTTAVSSVLLAPSVFQQTVTRSSDLERK 520
                   + P   +  +  +  P++    T T T  S  +L PS        S  +  +
Sbjct: 184 LTPSSTPTLTPS-STPTLTPSSRPILTRSSTPTLTPSSRPILTPSSTPTLTPSSRPILTR 242

Query: 521 ASSPSPLTIGTP 532
           +S+P+     TP
Sbjct: 243 SSTPTLTPSSTP 254



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 54/234 (23%), Positives = 89/234 (38%), Gaps = 22/234 (9%)

Query: 283 SVQPEITTPVLITPASITQSNEKHAPTYTIPLSPVLSPT-----LPAEAPTAQVPPSLPR 337
           S  P +T   ++T +S         PT T   +P L+P+      P+  PT  + PS   
Sbjct: 77  SSTPTLTPQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLTPSNTPT--LTPSSTP 134

Query: 338 NSTMMQAVKTTPRQRSPLLNQPVPELSHAS---LIANQSPFRAPLNVTNTAGTSLPSVDL 394
             T       TP  R  L     P L+ +S   L  + +P   P +      +S P++  
Sbjct: 135 TLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSSTPTLTP 194

Query: 395 LQKLRLTPQHDQIQTQPLGKGAMVASFSPAAGQLATPESFIEPPSKTAAARVAASASLSN 454
                LTP      ++P+   +   + +P++  + TP S    P+ T ++R   + S S 
Sbjct: 195 SSTPTLTP-----SSRPILTRSSTPTLTPSSRPILTPSS---TPTLTPSSRPILTRS-ST 245

Query: 455 MVLAPLQSMQQNQDPEVFVQPK---VLSSAIQVAGAPLVTATTTAVSSVLLAPS 505
             L P  +          + P     L+ +      P  T T T  S+  L PS
Sbjct: 246 PTLTPSSTPTLTPSNTPTLTPSNTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPS 299



 Score = 36.2 bits (82), Expect = 0.085
 Identities = 50/227 (22%), Positives = 85/227 (37%), Gaps = 28/227 (12%)

Query: 314 LSPVLSPTLPAEAPTAQVPPSLPRNSTMMQAVKTTPRQRSPLLNQPVPELSHASLIANQS 373
           L+P  +PTL   +P    P S P  +   Q + T  R  +P L    P     +L  + +
Sbjct: 2   LTPSNTPTLTPSSPPTLTPSSTPTLTPSSQPILT--RSSTPTLTPSSP----PTLTPSNT 55

Query: 374 PFRAPLNVTNTAGTSLPSVDLLQKLRLTPQHDQIQTQPLGKGAMVASFSPAAGQLATPES 433
           P   P N      +S P++       LTP       QP+   +   + +P++    TP +
Sbjct: 56  PTLTPSNTPTLTPSSTPTLTPSSTPTLTP-------QPILTRSSTPTLTPSSPPTLTPSN 108

Query: 434 --FIEP-------PSKTAAARVAASASL---SNMVLAPLQSMQQNQDPEVFVQPK---VL 478
              + P       PS T     +++ +L   S   L P       +     + P    +L
Sbjct: 109 TPTLTPSNTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPIL 168

Query: 479 SSAIQVAGAPLVTATTTAVSSVLLAPSVFQQTVTRSSDLERKASSPS 525
           + +      P  T T T  S+  L PS        S  +  ++S+P+
Sbjct: 169 TRSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPT 215


>gi|148612835 zinc finger protein 207 isoform c [Homo sapiens]
          Length = 494

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 49/223 (21%), Positives = 79/223 (35%), Gaps = 28/223 (12%)

Query: 313 PLSPVLSPTLPAEAPTAQVPPSLPRNSTMMQAVKTTPRQRSPLLNQPVPELSHASLIANQ 372
           PL P + P +P   P   +PP     +     +   P   +  +  P P ++   L  + 
Sbjct: 216 PLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQPPVT-KPLFPSA 274

Query: 373 SPFRAPLNVTNTAGTSLPSVDLLQKLRLTPQHDQIQTQPLGKGAMVASFSPAAGQLATPE 432
                P+  ++TA ++  S+    K  L P     Q Q   +G +   F P     +TP 
Sbjct: 275 GQMGTPVTSSSTASSNSESLSASSK-ALFP--STAQAQAAVQGPVGTDFKPLN---STPA 328

Query: 433 SFIEPPSKTAAARVAASASLSNMVLAPLQSMQQNQDPEVFVQPKVLSSAIQVAGAPLVTA 492
           +  EPP  T  A   ++AS ++                          A  +   P  T 
Sbjct: 329 TTTEPPKPTFPAYTQSTASTTST-----------------TNSTAAKPAASITSKP-ATL 370

Query: 493 TTTAVSSVLLAPSVFQQTVTRSSDL---ERKASSPSPLTIGTP 532
           TTT+ +S L+ P        R + L   +R    P    IG P
Sbjct: 371 TTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNP 413


>gi|4508017 zinc finger protein 207 isoform a [Homo sapiens]
          Length = 478

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 49/223 (21%), Positives = 79/223 (35%), Gaps = 28/223 (12%)

Query: 313 PLSPVLSPTLPAEAPTAQVPPSLPRNSTMMQAVKTTPRQRSPLLNQPVPELSHASLIANQ 372
           PL P + P +P   P   +PP     +     +   P   +  +  P P ++   L  + 
Sbjct: 200 PLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQPPVT-KPLFPSA 258

Query: 373 SPFRAPLNVTNTAGTSLPSVDLLQKLRLTPQHDQIQTQPLGKGAMVASFSPAAGQLATPE 432
                P+  ++TA ++  S+    K  L P     Q Q   +G +   F P     +TP 
Sbjct: 259 GQMGTPVTSSSTASSNSESLSASSK-ALFP--STAQAQAAVQGPVGTDFKPLN---STPA 312

Query: 433 SFIEPPSKTAAARVAASASLSNMVLAPLQSMQQNQDPEVFVQPKVLSSAIQVAGAPLVTA 492
           +  EPP  T  A   ++AS ++                          A  +   P  T 
Sbjct: 313 TTTEPPKPTFPAYTQSTASTTST-----------------TNSTAAKPAASITSKP-ATL 354

Query: 493 TTTAVSSVLLAPSVFQQTVTRSSDL---ERKASSPSPLTIGTP 532
           TTT+ +S L+ P        R + L   +R    P    IG P
Sbjct: 355 TTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNP 397


>gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]
          Length = 2639

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 71/348 (20%), Positives = 118/348 (33%), Gaps = 24/348 (6%)

Query: 190  SNLGSTETLEEMPSGSQDKSAPS-GHKHLTVEELFGTSLPKEQPAVVGLDSEEMERLPGD 248
            S+ G  ET + +    +D    S    HL++E+L G  +       VGL  +  ++ PG 
Sbjct: 1219 SDDGDRETFDGVCGAPEDIECRSVKDPHLSLEQL-GQKVQLVCDVSVGLICKNEDQKPGG 1277

Query: 249  ASQKEPNSFLPFPFEQLGGAPQSETLGVPSAAHHSVQPEITTPVLITPASITQSNEKHAP 308
                          +      Q  T+   +  + +  P ITT   +TP     S +   P
Sbjct: 1278 VIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPTP-ITTTTTVTPTPTPTSTQSTTP 1336

Query: 309  TYTIPLSPVLSPTLPAEAPT-AQVPPSLPRNSTMMQAVKTTPRQRSPLLNQPVPELSHA- 366
            T   P++   + T P   PT  Q P + P  +T       TP         P+   +   
Sbjct: 1337 T---PITTTTTVT-PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 1392

Query: 367  ---SLIANQSPFRAPLNVTNTAGTSLPSVDLLQKLRLTPQHDQIQTQPLGKGAMVASFSP 423
               +    Q+P   P+  T T  T  P+    Q    TP        P        + +P
Sbjct: 1393 PTPTPTGTQTPTSTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTP 1451

Query: 424  AAGQLATPESFIEPPSKTAAARVAASASLSNMVLAPLQSMQQNQDPEVFVQPKVLSSAIQ 483
             A  + T  +    P+ T       +   +   + P  +    Q P     P  +++   
Sbjct: 1452 TA--ITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP----TPTAITTTTT 1505

Query: 484  VAGAPLVTATTTAVSSVLLAPSVFQQTVTRSSDLERKASSPSPLTIGT 531
            V   P  T T T  S+ +   +    T T +        +P+P  I T
Sbjct: 1506 VTPTPTPTGTQTPTSTPITTTTTVTPTPTPTG-----TQTPTPTPIST 1548



 Score = 31.6 bits (70), Expect = 2.1
 Identities = 55/284 (19%), Positives = 89/284 (31%), Gaps = 24/284 (8%)

Query: 277  PSAAHHSVQPEITTPVLITPASITQSNEKHAPTYTIPLSPVLSPTLPAEAPT-AQVPPSL 335
            P+         ITT   +TP       +   PT     S V     P   PT  Q P + 
Sbjct: 1420 PTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTV----TPTPTPTGTQTPTTT 1475

Query: 336  PRNSTMMQAVKTTPRQRSPLLNQPVPELSHASL------IANQSPFRAPLNVTNTAGTSL 389
            P  +T    V  TP         P    +  ++         Q+P   P+  T T  T  
Sbjct: 1476 PITTT--TTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTV-TPT 1532

Query: 390  PSVDLLQKLRLTP--QHDQIQTQPLGKGAMVASFSPAAGQLATPESFIEPPSKTAAARVA 447
            P+    Q    TP      +   P   G    + +P      T  +    P+ T      
Sbjct: 1533 PTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPIT--TTTTVTPTPTPTGTQTPTTV 1590

Query: 448  ASASLSNMVLAPLQSMQQNQDPEVFVQPKVLSSAIQVAGA------PLVTATTTAVSSVL 501
               + + M   P  +  ++           +++     G       P+ T TT   +   
Sbjct: 1591 LITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTP 1650

Query: 502  LAPSVFQQTVTRSSDLERKASSPSPLTIGTPESQRKPSIILSKS 545
               S    T T ++ +    +S  P    TP++ R  S  L++S
Sbjct: 1651 TTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTES 1694


>gi|98986457 host cell factor 1 [Homo sapiens]
          Length = 2035

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 77/358 (21%), Positives = 126/358 (35%), Gaps = 33/358 (9%)

Query: 167  EYERNQMGDSNISSPGLQPSTQLSNLGSTETLEEMPSGSQDKSAPSGHKHLTVEELFGTS 226
            E E  Q    NI+S     +T  S L    T     +     S P        EEL  + 
Sbjct: 1455 EVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPP------EELQVSP 1508

Query: 227  LPKEQPAVVGLDSEEMERLPGDASQKEPNSFLPFPFEQLGGAPQSETLGVPSAAHHSVQP 286
             P++Q     L       L G++++    S  P    +L  A    + G PS+   S   
Sbjct: 1509 GPRQQLPPRQLLQSASTALMGESAEVLSASQTP----ELPAAVDLSSTGEPSSGQESAGS 1564

Query: 287  EITTPVLITPASITQSN------------EKHAPTYTIPLSPV----LSPTLPAEAPTAQ 330
             +   V++ P   TQS             E  A T T+ ++ +    L+ T  AEA  AQ
Sbjct: 1565 AVVATVVVQPPPPTQSEVDQLSLPQELMAEAQAGTTTLMVTGLTPEELAVTAAAEA-AAQ 1623

Query: 331  VPPSLPRNSTMMQAVKTTPRQRSPLLNQPVPELSHASLIANQSPFRAPLNVTNTAGTSLP 390
               +    +  +QAV    +Q      +P+     A+ +                 T++P
Sbjct: 1624 AAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQATTIP 1683

Query: 391  SVDLLQKLRLTPQHDQIQTQPLGKGAMVASFSPAAGQLATPESFIEPPSKTAAARVAASA 450
             V   Q+L    Q  Q+Q       A           LA  +S  +P  ++      A  
Sbjct: 1684 IVLTQQELAALVQQQQLQEAQ----AQQQHHHLPTEALAPADSLNDPAIESNCLNELAGT 1739

Query: 451  SLSNMVLAPLQSMQQNQDPEVFV--QPKVLSSAIQVAGAPLVTATTTAVSSVLLAPSV 506
              S + L P  + +       FV  QP V++S  ++  A  +T     + S+ + P +
Sbjct: 1740 VPSTVALLPSTATESLAPSNTFVAPQPVVVASPAKLQAAATLTEVANGIESLGVKPDL 1797



 Score = 30.0 bits (66), Expect = 6.1
 Identities = 52/253 (20%), Positives = 90/253 (35%), Gaps = 17/253 (6%)

Query: 294 ITPASITQSNEKHAPTYTIPLSPVLSPTLPAEAPTAQVPPSLPRNSTMMQAVKTTPRQRS 353
           I   + T ++    P  ++P +P  SP   A AP  Q P +    + + QA    P   +
Sbjct: 402 IPATAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQ-PLTQVGITLLPQAAPAPPTTTT 460

Query: 354 PLLNQPVPELS-HASLIANQSPFRAPLNVTNTAGTSLPSVDLLQKLRLTPQHDQIQTQPL 412
             +   VP  S      A      A L VT    T+            TP          
Sbjct: 461 IQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATT-----------GTPLVTMRPASQA 509

Query: 413 GKGAMVASFSPAAGQLATPESFIEPPSKTAAARVAASASLSNMVLAPLQSMQQNQDPEVF 472
           GK  +  +  PA  ++  P    +     ++ +++  A+L+    A  Q +  +  P V 
Sbjct: 510 GKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALA-AAAAATQKIPPSSAPTVL 568

Query: 473 VQPKVLSSAIQVAGAPLVTATTTAVSSVLLAPSVFQQTVTRSSDLERKASSPSPLTIGTP 532
             P   +    +A  P    TTT  ++V +A S    +   +  L+  A+          
Sbjct: 569 SVPAGTTIVKTMAVTP---GTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSAT 625

Query: 533 ESQRKPSIILSKS 545
            +  +P I + KS
Sbjct: 626 NTSTRPIITVHKS 638


>gi|83367077 mucin 16 [Homo sapiens]
          Length = 14507

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 93/432 (21%), Positives = 167/432 (38%), Gaps = 57/432 (13%)

Query: 129  ETRRSQQAARDKQSPS---QANGCSDHRPIDILEMLSR----AKDEYERNQMGDSNISS- 180
            ET R Q+ +    SP      +       I+   +LS     A  E  R ++  S+ +S 
Sbjct: 7232 ETSRIQKESISSLSPKLRETGSSVETSSAIETSAVLSEVSIGATTEISRTEVTSSSRTSI 7291

Query: 181  PGLQPSTQLSNLGSTETLEEMPSGS----------QDKSAPSGHKHLTVEELFGTSLPKE 230
             G   ST L  + +T  + + P+            + +++P G    T E  F T     
Sbjct: 7292 SGSAESTMLPEISTTRKIIKFPTSPILAESSEMTIKTQTSPPGS---TSESTF-TLDTST 7347

Query: 231  QPAVVGLDSEEMERLPGDASQKEPNSFLPFPFEQLGGAPQSETLGVPSAAHHSVQPEITT 290
             P++V   S   +RLP        +          G  P+  +L V   +  S Q  ++ 
Sbjct: 7348 TPSLVITHSTMTQRLPH-------SEITTLVSRGAGDVPRPSSLPVEETSPPSSQLSLSA 7400

Query: 291  PVLITPASITQSNEKHAPTYTIPLSPVLSP-------TLPAEA-PTAQVPPSLPRNSTMM 342
             +  +P S T     H+ + ++  + +L+P        L A A P    PPSL   S  +
Sbjct: 7401 MISPSPVSSTLPASSHSSSASV--TSLLTPGQVKTTEVLDASAEPETSSPPSLSSTSVEI 7458

Query: 343  QA---VKTTPRQRSPLLNQPVPELSHASLIANQSPFRA-PLNVTNTAGTSLPSVDLLQKL 398
             A   V T   +  P  N  V ++  +S   ++SP    P + T  A +++ ++ ++   
Sbjct: 7459 LATSEVTTDTEKIHPFSNTAVTKVGTSSS-GHESPSSVLPDSETTKATSAMGTISIMGDT 7517

Query: 399  R---LTPQHD---QIQTQPLG------KGAMVASFSPAAGQLATPESFIEPPSKTAAARV 446
                LTP      +IQ++P        +    +  +  A +  T  S +   + T  +R 
Sbjct: 7518 SVSTLTPALSNTRKIQSEPASSLTTRLRETSTSEETSLATEANTVLSKVSTGATTEVSRT 7577

Query: 447  AASASLSNMVLAPLQSMQQNQDPEVFVQPKVLSSAIQVAGAPLVTATTTAVSSVLLAPSV 506
             A +     +  P QS   +QD  +   P++ +S++    A +   T T  S   L  ++
Sbjct: 7578 EAISFSRTSMSGPEQSTM-SQDISIGTIPRISASSVLTESAKMTITTQTGPSESTLESTL 7636

Query: 507  FQQTVTRSSDLE 518
               T T  S +E
Sbjct: 7637 NLNTATTPSWVE 7648



 Score = 34.7 bits (78), Expect = 0.25
 Identities = 65/293 (22%), Positives = 115/293 (39%), Gaps = 41/293 (13%)

Query: 289   TTPVLITPASITQSNEKHAPTYTIPLSPVLSPTLPAEAPTAQVPPSLPRNSTMMQAVKTT 348
             TTP + T      S+    PT +  +  V++P + +    A +  ++P  +      +TT
Sbjct: 10849 TTPSMTTSHGAESSSAVPTPTVSTEVPGVVTPLVTSSR--AVISTTIPILTLSPGEPETT 10906

Query: 349   PRQRSPLLNQPVPELSHASLIANQSPFRAPLNVTNTAGTSLPSV--DLLQKLR-LTPQHD 405
             P   +          SH    ++  P       T T    +P V   L+   R +T    
Sbjct: 10907 PSMAT----------SHGEEASSAIP-------TPTVSPGVPGVVTSLVTSSRAVTSTTI 10949

Query: 406   QIQTQPLGKG----AMVASFSPAAGQLATPESFIEPP----SKTAAARVAASASLSNMVL 457
              I T  LG+     +M  S    AG  A P    E P    S  A++R   S +L  + L
Sbjct: 10950 PILTFSLGEPETTPSMATSHGTEAGS-AVPTVLPEVPGMVTSLVASSRAVTSTTLPTLTL 11008

Query: 458   APLQ-----SMQQNQDPEVFVQPKVLSSAIQVAGAPLVTATT----TAVSSVLLAPSVFQ 508
             +P +     SM  +   E       +S  +      LVT+++    T++ +++L+P   +
Sbjct: 11009 SPGEPETTPSMATSHGAEASSTVPTVSPEVPGVVTSLVTSSSGVNSTSIPTLILSPGELE 11068

Query: 509   QTVTRSSDLERKASSPSPL-TIGTPESQRKPSIILSKSQLQDTLIHLIKNDSS 560
              T + ++    +ASS  P  T+    S     ++ S   +  T I ++   SS
Sbjct: 11069 TTPSMATSHGAEASSAVPTPTVSPGVSGVVTPLVTSSRAVTSTTIPILTLSSS 11121



 Score = 34.3 bits (77), Expect = 0.32
 Identities = 65/313 (20%), Positives = 120/313 (38%), Gaps = 37/313 (11%)

Query: 247  GDASQKEPNSFLPFPFEQLGGAPQSETLGVPSAAHHSVQPE-----------ITTPVLIT 295
            G +S   P      P     G+ +S  LG+ S++  S  P+           +TT +++ 
Sbjct: 1124 GTSSALTPQMTATHPPSPDPGSARSTWLGILSSSPSSPTPKVTMSSTFSTQRVTTSMIMD 1183

Query: 296  PASITQSNEKHAPTYTIPLSPVLSPTLPAEAPTAQVPPSLPRNSTMMQAVK-TTPRQRSP 354
                ++ N  + P+ T  L+P   PT  A   +  VP   P  +T ++A +   P   + 
Sbjct: 1184 TVETSRWNMPNLPS-TTSLTPSNIPTSGAIGKSTLVPLDTPSPATSLEASEGGLPTLSTY 1242

Query: 355  LLNQPVPELSHASLIANQSPFRAPLNVTNT------AGTSLPSVDLLQKLRLTPQHDQIQ 408
              +   P +   +  +++SP    L + +          + PS++       T  H    
Sbjct: 1243 PESTNTPSIHLGAHASSESPSTIKLTMASVVKPGSYTPLTFPSIE-------THIHVSTA 1295

Query: 409  TQPLGKGA---MVASFSPAAGQLATPESFI--EPPSKTAAARVAASASLSNMVLAPLQSM 463
                  G+   M A      G    P ++I    P  T++A+V+   S+  +        
Sbjct: 1296 RMAYSSGSSPEMTAPGETNTGSTWDPTTYITTTDPKDTSSAQVSTPHSVRTLRTTENHPK 1355

Query: 464  QQNQDPEVFV-QPKVLSSAIQVAGAPLV-TATTTAVSSVLLAPSVFQQTVTRSSDLERKA 521
             ++  P  +   PK+ SS    + A    T T T   S  L    + +   +SS  E + 
Sbjct: 1356 TESATPAAYSGSPKISSSPNLTSPATKAWTITDTTEHSTQLH---YTKLAEKSSGFETQ- 1411

Query: 522  SSPSPLTIGTPES 534
            S+P P+++  P S
Sbjct: 1412 SAPGPVSVVIPTS 1424



 Score = 34.3 bits (77), Expect = 0.32
 Identities = 60/311 (19%), Positives = 110/311 (35%), Gaps = 33/311 (10%)

Query: 239  SEEMERLPGDASQKEPNSFLPFPFEQLGGAPQSETLGVPSAAHHSVQPEITTPVLITPAS 298
            S+  E+ P         +     F+  G     E    PS A H  +P + T     P  
Sbjct: 2930 SKSPEKNPRARMMTSTKAISASSFQSTGFTETPEGSASPSMAGH--EPRVPTSGTGDPRY 2987

Query: 299  ITQSNEKHAPTYTIPLSPVLSPTLPAEAPTAQVPPSLPRNSTMMQAVKTTPRQRSPLLNQ 358
             ++S     P+     S + S +L ++  T        R+ +    +  +  + +  L+ 
Sbjct: 2988 ASESMSYPDPSKAS--SAMTSTSLASKLTTLFSTGQAARSGSSSSPISLSTEKETSFLSP 3045

Query: 359  PVPELSHASLIANQSPFRAP---LNVTNTAGTSLPSVDLLQKLRLTPQHDQIQTQPLGKG 415
                    SL    S  R P   +++  +A T  P+  L       P+    QT      
Sbjct: 3046 TASTSRKTSLFLGPSMARQPNILVHLQTSALTLSPTSTLNMSQEEPPELTSSQT------ 3099

Query: 416  AMVASFSPAAGQLATPESFIEPPSKTAAARVAASASLSNMVLAPLQSMQQNQDPEVFVQP 475
                  +   G  A  ++    PS+T  + +  S+        P +   + +       P
Sbjct: 3100 -----IAEEEGTTAETQTLTFTPSETPTSLLPVSS--------PTEPTARRKS-----SP 3141

Query: 476  KVLSSAIQVAGAPLVTATT--TAVSSVLLAPSVFQQTVTRSSDLERKASSPSPLTIGTPE 533
            +  +S+I V     +  TT  T V+++ ++    Q   T  +  E   SSP+  + G+PE
Sbjct: 3142 ETWASSISVPAKTSLVETTDGTLVTTIKMSSQAAQGNSTWPAPAEETGSSPAGTSPGSPE 3201

Query: 534  SQRKPSIILSK 544
                  I+ SK
Sbjct: 3202 MSTTLKIMSSK 3212



 Score = 32.3 bits (72), Expect = 1.2
 Identities = 89/399 (22%), Positives = 143/399 (35%), Gaps = 61/399 (15%)

Query: 194  STETLEEMPSGSQDKSAPSGHKHLTVEELFGTSLPKEQ--------PAVVGLDSEEMERL 245
            ST   EEM S   D S+PS     T       S P  +         A+   DS  +++ 
Sbjct: 1462 STSLTEEMASTDLDISSPSSPMS-TFAIFPPMSTPSHELSKSEADTSAIRNTDSTTLDQH 1520

Query: 246  PGDASQKEPNSFLPFPFEQLGGAPQSETLGVPSAAHHSVQPEITTPVLITPASITQS--N 303
             G  S          P   L       T    S   HS Q + T    ++P  +TQS  +
Sbjct: 1521 LGIRSLGRTGDLTTVPITPL-------TTTWTSVIEHSTQAQDTLSATMSPTHVTQSLKD 1573

Query: 304  EKHAPTYTIP--LSPVLSPTLPAEAPTAQVPPSL--PRNSTMMQAVKTTPR--QRSPLLN 357
            +   P    P  L+ V  P L  +  ++    +   P   T+ + ++T P   Q +P ++
Sbjct: 1574 QTSIPASASPSHLTEVY-PELGTQGRSSSEATTFWKPSTDTLSREIETGPTNIQSTPPMD 1632

Query: 358  QPVPELSHASL--------IANQSPFRAPLNVTNTAGTSLPSVDL--LQKLRLTPQHDQI 407
                  S + +        I   SP     N+     +S  +V +     L +T    + 
Sbjct: 1633 NTTTGSSSSGVTLGIAHLPIGTSSPAETSTNMALERRSSTATVSMAGTMGLLVTSAPGRS 1692

Query: 408  QTQPLGKGAMVASFSPAAGQLATPESFIEPPSKTAAARVAASASL-------SNMVLA-P 459
             +Q LG+ + V S S   G   T  S    P        A S+SL       S M  + P
Sbjct: 1693 ISQSLGRVSSVLSESTTEG--VTDSSKGSSPRLNTQGNTALSSSLEPSYAEGSQMSTSIP 1750

Query: 460  LQSMQQNQDPEVF--------VQPKVLSSAIQVAGAPLVTATTTAVSSVLLAPSVFQQTV 511
            L S     D E              V++S I  + A   +++ T +S+ L +        
Sbjct: 1751 LTSSPTTPDVEFIGGSTFWTKEVTTVMTSDISKSSARTESSSATLMSTALGS-------- 1802

Query: 512  TRSSDLERKASSPSPLTIGTPESQRKPSIILSKSQLQDT 550
            T ++  E+  ++   L   TP  +  P I L+ S   +T
Sbjct: 1803 TENTGKEKLRTASMDLPSPTPSMEVTPWISLTLSNAPNT 1841



 Score = 32.3 bits (72), Expect = 1.2
 Identities = 56/262 (21%), Positives = 97/262 (37%), Gaps = 33/262 (12%)

Query: 286  PEITTPVLITPASITQSNEKHAPTYTIPLSP------VLSPTLPAEAPTAQVPPSLPRNS 339
            P I T      A+    +E H+P      +P      V++ T+   AP+  +P      +
Sbjct: 5119 PSINTEETNVKAN-NSGHESHSPALADSETPKATTQMVITTTVGDPAPSTSMPVHGSSET 5177

Query: 340  TMMQAVKT---TPRQRSPLLNQPVPELSHASLIANQSPFRAPLNVTNTAGTSLPSVDLLQ 396
            T ++   T   TPR R    +Q     +  S + ++ P      V++T   S   +    
Sbjct: 5178 TNIKREPTYFLTPRLRETSTSQESSFPTDTSFLLSKVPTGTITEVSSTGVNSSSKIS--- 5234

Query: 397  KLRLTPQHDQIQTQPLGKGAMVASFSPAAGQLATPESFIEPPSKTAAARVAASASLSNMV 456
                TP HD+    P      +     ++ +  + E  I     T  A    SAS S + 
Sbjct: 5235 ----TPDHDKSTVPPDTFTGEIPRVFTSSIKTKSAEMTI-----TTQASPPESASHSTLP 5285

Query: 457  LAPLQSMQQNQDPEVFVQPKVLSSAIQVAG----------APLVTATTTAVSSVLLAPSV 506
            L    ++ Q        Q    S    + G           P V  T++ VSS++ +P++
Sbjct: 5286 LDTSTTLSQGGTHSTVTQGFPYSEVTTLMGMGPGNVSWMTTPPVEETSS-VSSLMSSPAM 5344

Query: 507  FQQTVTRSSDLERKASSPSPLT 528
               +   S+  +   SSP P+T
Sbjct: 5345 TSPSPVSSTSPQSIPSSPLPVT 5366



 Score = 32.3 bits (72), Expect = 1.2
 Identities = 86/403 (21%), Positives = 162/403 (40%), Gaps = 57/403 (14%)

Query: 176  SNISSPGLQPSTQLSNLGSTETLEEMPSGSQDKSAPSGHK------HLTVEELFGTSLPK 229
            +N  +     +T  +N+G+T ++ ++ S     S PSGH        +  + +  TS P 
Sbjct: 6000 TNTETIHFSENTAETNMGTTNSMHKLHSSVSIHSQPSGHTPPKVTGSMMEDAIVSTSTP- 6058

Query: 230  EQPAVVGLDSEEMERLPGDASQKEPNSFLPFPFEQLGGAPQSETLGVPSAAHHSVQPEIT 289
              P    +D +    L  +   KE ++ L      +    +S T+        SV  +  
Sbjct: 6059 GSPETKNVDRDSTSPLTPEL--KEDSTAL-----VMNSTTESNTV------FSSVSLDAA 6105

Query: 290  TPVLITPASITQSNEKHAP-TYTIPLSPVLSPTLPAEAPTAQVPPSLPRNSTMMQAVKTT 348
            T V  + A +T  +    P +     SP +SP   A +  +  PP        +   KT 
Sbjct: 6106 TEV--SRAEVTYYDPTFMPASAQSTKSPDISP--EASSSHSNSPP------LTISTHKTI 6155

Query: 349  PRQRSPLLNQPVPELS-HASLIANQ--SPFRAPLNVTNTAGTSLPSVDLLQKLRLTPQHD 405
              Q  P     + +L+   S IA    +P     +  ++  TS+ + DL   L+ +P   
Sbjct: 6156 ATQTGPSGVTSLGQLTLDTSTIATSAGTPSARTQDFVDSETTSVMNNDLNDVLKTSPFSA 6215

Query: 406  QIQTQPLGKGAMVASFSPAAGQLATPESFIEPPSKTAAARVAASASLSNMVLAPLQSMQQ 465
            +       +  ++ + SP+       E         + + + +  S+    LA +  M  
Sbjct: 6216 EEANSLSSQAPLLVTTSPSPVTSTLQEH--------STSSLVSVTSVPTPTLAKITDMDT 6267

Query: 466  NQDPEVFVQPKVLSSAIQVAGAPLVTAT-----TTAVSSV--LLAPSVFQQTVTRSSDLE 518
            N +P V   P+ L + +  + A   T T      TAV++V    +P+ F  TV+  SD  
Sbjct: 6268 NLEP-VTRSPQNLRNTLATSEATTDTHTMHPSINTAVANVGTTSSPNEFYFTVSPDSD-P 6325

Query: 519  RKASSPSPLTIGTPESQRKPSIILSKSQLQDTLIHLIKNDSSF 561
             KA+S   +T  + +S      I+S S  + + +  I+++++F
Sbjct: 6326 YKATSAVVITSTSGDS------IVSTSMPRSSAMKKIESETTF 6362



 Score = 32.0 bits (71), Expect = 1.6
 Identities = 80/344 (23%), Positives = 116/344 (33%), Gaps = 64/344 (18%)

Query: 161  LSRAKDEYERNQMGDSNISSPGLQPSTQL--SNLGSTETLEEMPSGSQDKSAPSGHKHLT 218
            LS   DE  R   G    ++  + PST    SN+    +  E PS +   S  S      
Sbjct: 7155 LSHTSDE--RLTTGKDTTNTEAVHPSTNTAASNVEIPSSGHESPSSALADSETSK----A 7208

Query: 219  VEELFGTSLPKEQPAVVGLDSEEMERLPGDASQKEPNSFLPFPFEQLGGAPQSETLGVPS 278
               +F TS  ++    +         L     QKE  S L     + G + ++ +    S
Sbjct: 7209 TSPMFITSTQEDTTVAISTP----HFLETSRIQKESISSLSPKLRETGSSVETSSAIETS 7264

Query: 279  AAHHSVQPEITTPVL---ITPASITQSNEKHAPTYT-----------IPLSPVLSPTLPA 324
            A    V    TT +    +T +S T  +     T              P SP+L+ +   
Sbjct: 7265 AVLSEVSIGATTEISRTEVTSSSRTSISGSAESTMLPEISTTRKIIKFPTSPILAESSEM 7324

Query: 325  EAPTAQVPPSLPRNSTMMQAVKTTP---------RQRSP------LLNQ----------- 358
               T   PP     ST      TTP          QR P      L+++           
Sbjct: 7325 TIKTQTSPPGSTSESTFTLDTSTTPSLVITHSTMTQRLPHSEITTLVSRGAGDVPRPSSL 7384

Query: 359  PVPELSHASLIANQSPFRAPLNVTNTAGTSLPSVDLLQKLRLTPQHDQIQTQPLGKGAMV 418
            PV E S  S   + S   +P  V++T   S  S        LTP   +  T+ L   A  
Sbjct: 7385 PVEETSPPSSQLSLSAMISPSPVSSTLPASSHSSSASVTSLLTPGQVK-TTEVLDASAEP 7443

Query: 419  ASFSP-----------AAGQLATPESFIEPPSKTAAARVAASAS 451
             + SP           A  ++ T    I P S TA  +V  S+S
Sbjct: 7444 ETSSPPSLSSTSVEILATSEVTTDTEKIHPFSNTAVTKVGTSSS 7487



 Score = 31.6 bits (70), Expect = 2.1
 Identities = 25/104 (24%), Positives = 41/104 (39%), Gaps = 17/104 (16%)

Query: 226  SLPKEQPAVVGLDSEEMERLPGDASQKEPNSFLPFPFEQLGGAP---------QSETLGV 276
            S+P +   V   D   +  +   +   + NS  P P E+ G +P          S TL +
Sbjct: 3149 SVPAKTSLVETTDGTLVTTIKMSSQAAQGNSTWPAPAEETGSSPAGTSPGSPEMSTTLKI 3208

Query: 277  PSAAHHSVQPEITTPVLITPASITQSNEKHAPTYTIPLSPVLSP 320
             S+   S+ PEI + V  +P           P  T+P+   + P
Sbjct: 3209 MSSKEPSISPEIRSTVRNSPWK--------TPETTVPMETTVEP 3244



 Score = 30.0 bits (66), Expect = 6.1
 Identities = 30/140 (21%), Positives = 54/140 (38%), Gaps = 2/140 (1%)

Query: 384  TAGTSLPSVDLLQKLRLTPQHDQIQTQPLGKGAMVASFSPAAGQLATPESFIEPPSKTAA 443
            T G S P V     +  T Q   + + P G   + +  +P+ G+ ++  S   P      
Sbjct: 3439 TLGAS-PDVTNTLYITSTAQTTSLVSLPSGDQGITSLTNPSGGKTSSASSVTSPSIGLET 3497

Query: 444  ARVAASASLSNMVLAPLQSMQQNQDPEVFVQPKVLSSAIQVAGAPLVTATTTAVSSVLLA 503
             R   SA  S++        Q +   EV +   V ++        + T  T ++S+    
Sbjct: 3498 LRANVSAVKSDIAPTAGHLSQTSSPAEVSIL-DVTTAPTPGISTTITTMGTNSISTTTPN 3556

Query: 504  PSVFQQTVTRSSDLERKASS 523
            P V   T+  +   ER+ +S
Sbjct: 3557 PEVGMSTMDSTPATERRTTS 3576



 Score = 29.6 bits (65), Expect = 8.0
 Identities = 70/357 (19%), Positives = 121/357 (33%), Gaps = 42/357 (11%)

Query: 194  STETLEEMPSGSQDKSAPSGHKHLTVEELFGTSLPKEQPAVVGLDSEEMERLPGDASQKE 253
            +T  +EE  S S   S+P+      V      S+P     V  L +  +           
Sbjct: 5325 TTPPVEETSSVSSLMSSPAMTSPSPVSSTSPQSIPSSPLPVTALPTSVLVTTTDVLGTTS 5384

Query: 254  PNSFLPFP-----FEQLGGAPQSETLGVPSAAHHSVQPEITTPVLITPASITQSNEKHAP 308
            P S    P           A   +T    +A HHS    +T        ++  S   H  
Sbjct: 5385 PESVTSSPPNLSSITHERPATYKDTAHTEAAMHHSTNTAVT--------NVGTSGSGHKS 5436

Query: 309  TYTIPLSPVLSPTLPAEAPTAQVPPSLPRNSTM--MQAVKTTPR--QRSPLLNQPVPELS 364
                  S VL     A++ T++  P +   ST+       +TP   Q + +  +P   LS
Sbjct: 5437 Q-----SSVL-----ADSETSKATPLMSTTSTLGDTSVSTSTPNISQTNQIQTEPTASLS 5486

Query: 365  HASLIANQSPFRAPLNVTNTAGTSLPSVDLLQKLRLTPQHDQIQTQPLGKGAMVASFSPA 424
                 ++ S   +    TNTA + +P+  + Q  R      +     L +  +    S  
Sbjct: 5487 PRLRESSTSEKTSSTTETNTAFSYVPTGAITQASRTEISSSRTSISDLDRPTIAPDISTG 5546

Query: 425  A-GQLATPESFIEPPSKTAAARVAASASLSNMVL------APLQSMQQNQDPEVFVQPKV 477
               +L T     +    T   +     + S  +L         Q    +   + F   ++
Sbjct: 5547 MITRLFTSPIMTKSAEMTVTTQTTTPGATSQGILPWDTSTTLFQGGTHSTVSQGFPHSEI 5606

Query: 478  LSSAIQVAG------APLVTATTTAVSSVLLAPSVFQQTVTRSSDLERKASSPSPLT 528
             +   +  G       P V  T++  S  L++PS+   +   S+  E   SSP P+T
Sbjct: 5607 TTLRSRTPGDVSWMTTPPVEETSSGFS--LMSPSMTSPSPVSSTSPESIPSSPLPVT 5661


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 71/297 (23%), Positives = 87/297 (29%), Gaps = 25/297 (8%)

Query: 246  PGDASQKEPNSFLPFPFEQLGGAPQSETLGVPSAAHHSVQPEITTPVLITPASITQSNEK 305
            P   +   P +  P P       P + T   P     S  P  TTP+   PAS T     
Sbjct: 1464 PPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPS--PPTTTPIT-PPASTTT---- 1516

Query: 306  HAPTYTIPLSPVLSPTLPAEAPTAQVP---PSLPRNSTMMQAVKTTPRQRSPLLNQPVPE 362
              P  T P  P  + T P    T   P   P  P  ST      TTP    P      P 
Sbjct: 1517 -LPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTP-SPPPTTTTTPPP 1574

Query: 363  LSHASLIANQSPFRAPLNVTNTAGTSLPSVDLLQKLRLTPQHDQIQTQPLGKGAMVASFS 422
             +  S     +P    +  T    T+ PS         TP      + P           
Sbjct: 1575 TTTPSPPTTTTPSPPTITTTTPPPTTTPSPP--TTTTTTPPPTTTPSPP----TTTPITP 1628

Query: 423  PAAGQLATPESFIEPPSKTAAARVAASASLSNMVLAPLQSMQQNQDPEVFVQPKVLSSAI 482
            P +     P +   PP  T       +         P   +     P     P   SS I
Sbjct: 1629 PTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTP---SSPI 1685

Query: 483  QVAGAPLVTATTTAVSSVLLAPSVFQQTVTRSSDLERKASSPSPLTIGTPESQRKPS 539
                +P  T T T  S      S    T T SS       SP P T+ TP     PS
Sbjct: 1686 TTTPSP-PTTTMTTPSPTTTPSSPITTTTTPSS---TTTPSPPPTTMTTPSPTTTPS 1738



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 53/270 (19%), Positives = 77/270 (28%), Gaps = 20/270 (7%)

Query: 269  PQSETLGVPSAAHHSVQPEITTPVLITPASITQSNEKHAPTYTIPLSPVLSPTLPAEAPT 328
            P S T   P+          TTP   T  S   +     P  T P  P+ + T P    T
Sbjct: 1410 PTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTT 1469

Query: 329  AQVPPSLPRNSTMMQAVKTTPRQRSPLLNQPVPELSHASLIANQSPFRAPLNVTNTAGTS 388
               P + P   T   +  TT     P    P P  +        +P   P + T    T+
Sbjct: 1470 PSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTT--------TPITPPASTTTLPPTT 1521

Query: 389  LPSVDLLQKLRLTP--QHDQIQTQPLGKGAMVASFSPAAGQLATPESFIEPPSKTAAARV 446
             PS          P        T P+       +  P       P +   PP  T  +  
Sbjct: 1522 TPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPP 1581

Query: 447  AASASLSNMVLAPLQSMQQNQDPEVFVQPKVLSSA----IQVAGAPLVTATTTAVSSVLL 502
              +        +P         P     P   ++           P  T  T   S+  L
Sbjct: 1582 TTTTP------SPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTL 1635

Query: 503  APSVFQQTVTRSSDLERKASSPSPLTIGTP 532
             P+        ++      ++PSP T  TP
Sbjct: 1636 PPTTTPSPPPTTTTTPPPTTTPSPPTTTTP 1665



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 45/200 (22%), Positives = 66/200 (33%), Gaps = 22/200 (11%)

Query: 246  PGDASQKEPNSFLPFPFEQLGGAPQSETLGVPSAAHHSVQPEITTPVLITPASIT-QSNE 304
            P   +   P +  P P       P   T   P     +  P  TTP   T   IT  ++ 
Sbjct: 1573 PPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTST 1632

Query: 305  KHAPTYTIPLSPVLSPTLPAEAPTAQVPPSL------------PRNSTMMQAVKTTPRQR 352
               P  T P  P  + T P    T   P +             P  +T    + TTP   
Sbjct: 1633 TTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPP 1692

Query: 353  SPLLNQPVPELSHASLI-------ANQSPFRAPLNVTNTAGTSLPS--VDLLQKLRLTPQ 403
            +  +  P P  + +S I       +  +P   P  +T  + T+ PS     +  L  T  
Sbjct: 1693 TTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTT 1752

Query: 404  HDQIQTQPLGKGAMVASFSP 423
               + T PL       +FSP
Sbjct: 1753 SSPLTTTPLPPSITPPTFSP 1772



 Score = 33.1 bits (74), Expect = 0.72
 Identities = 52/263 (19%), Positives = 81/263 (30%), Gaps = 23/263 (8%)

Query: 288  ITTPVLITPASITQSNEKHAPTYTIPLSPVLSPTLPAEAPTA-QVPPSLPRNSTMMQAVK 346
            +T P  +T    T + E   P  T P++   + T P   PT  Q P + P  +T      
Sbjct: 1879 VTQPTTMT----TTTTENPTPPTTTPITTTTTVT-PTPTPTGTQTPTTTPITTTTTVTPT 1933

Query: 347  TTPRQRSPLLNQPVPELSHA----SLIANQSPFRAPLNVTNTAGTSLPSVDLLQKLRLTP 402
             TP         P+   +      +    Q+P   P+  T T  T  P+    Q    TP
Sbjct: 1934 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTP 1992

Query: 403  QHDQIQTQPLGKGAMVASFSPAAGQLATPESFIEPPSKTAAARVAASASLSNMVLAPLQS 462
                    P        + +P    + T  +    P+ T       +   +   + P  +
Sbjct: 1993 ITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2050

Query: 463  MQQNQDP-------EVFVQPKVLSSAIQVAGAPLVTATTTAVSSVLLAPSVFQQTVTRSS 515
                Q P          V P    +  Q      +T TTT   +         QT T + 
Sbjct: 2051 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTP 2107

Query: 516  DLERKASSPSPLTIGTPESQRKP 538
                   +P+P   GT      P
Sbjct: 2108 ITTTTTVTPTPTPTGTQTPTTTP 2130



 Score = 31.2 bits (69), Expect = 2.7
 Identities = 52/252 (20%), Positives = 80/252 (31%), Gaps = 21/252 (8%)

Query: 288  ITTPVLITPASITQSNEKHAPTYTIPLSPVLSPTLPAEAPTAQVPPSLPRNSTMMQAVKT 347
            ITTP   +P + T S    + T   P +    PT     P     PS P  +T      T
Sbjct: 1396 ITTP---SPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTT 1452

Query: 348  TPRQRSPLLNQPVPELSHASLIANQSPFRAPLNVTNTAGTSLPSVDLLQKLRLTPQHDQI 407
            TP         P P  + +      SP     +   T  T+ P          TP     
Sbjct: 1453 TPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTP----- 1507

Query: 408  QTQPLGKGAMVASFSPAAGQLAT----PESFIEPPSKTAAARVAASASL-SNMVLAPLQS 462
             T P     +  + +P+     T    P +   PP+ T      ++ +L      +P  +
Sbjct: 1508 ITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPT 1567

Query: 463  MQQNQDPEVFVQPKVLSSAIQVAGAPLVTATTTAVSSVLLAPSVFQQTVTRSSDLERKAS 522
                  P     P   ++       P +T TT   ++    P+    T T +       S
Sbjct: 1568 TTTTPPPTTTPSPPTTTT----PSPPTITTTTPPPTTTPSPPT----TTTTTPPPTTTPS 1619

Query: 523  SPSPLTIGTPES 534
             P+   I  P S
Sbjct: 1620 PPTTTPITPPTS 1631



 Score = 29.6 bits (65), Expect = 8.0
 Identities = 30/140 (21%), Positives = 47/140 (33%), Gaps = 26/140 (18%)

Query: 277  PSAAHHSVQPEITTPVLITPASITQSNEKHAPTY--TIPLSPVLSPTLPAEAPTAQ---- 330
            P+         ITT   +TP       +   PT+  T P++ + +   P E+ T Q    
Sbjct: 4167 PTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRS 4226

Query: 331  --------------VPPSLPRNSTMMQAVKTTPRQRSPLLNQPVPELSHASLIANQSPFR 376
                          +PP++   ST   +  T P   S       P  +        SP  
Sbjct: 4227 TSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPST------TTSPPG 4280

Query: 377  APLNVTNTAGTSLPSVDLLQ 396
             P   T T  +S P+   +Q
Sbjct: 4281 TPTRGTTTGSSSAPTPSTVQ 4300


>gi|239743232 PREDICTED: hypothetical protein XP_002342775 [Homo
           sapiens]
          Length = 834

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 95/403 (23%), Positives = 135/403 (33%), Gaps = 51/403 (12%)

Query: 135 QAARDKQSPSQANGCSDHRPIDILEMLSRAKDEYERNQMGDSNISSPGLQPSTQLSNLGS 194
           ++ +  Q+P     C +       E LS  K       +G S    PGL PS    +   
Sbjct: 183 ESLKKMQTPPSLPPCPESAGAATTEALSPPKTPNLLPPLGLSQSGPPGLLPSPSFDSNPP 242

Query: 195 TETLEEMPSGSQ----DKSAPSGHKHLTVEELFGTSLPKEQPAVVGLDSEEMERLPGDAS 250
           T  L  +P+ S     D  AP   +  T  +   TS P   P    L   +    P   +
Sbjct: 243 TTLLGLIPAPSMVPATDTKAPPTLQAETTTKPQATSAPSPAPKQSFLFGTQ-NTSPSSPA 301

Query: 251 QKEPNSFLPFPFEQLGGAPQSETLGVPSAAHHSVQPEITTPVLITPASITQSNEKHAPTY 310
               +S  P         P+SE  G P+    SV             S T  +    PT 
Sbjct: 302 APAASSASPMFKPIFTAPPKSEKEG-PTPPGPSV-------------SATAPSSSSLPTT 347

Query: 311 TIPLSPVLSPTLPAEAPTAQVPPSLP--RNSTMMQAVKTTPRQRSPLLNQPVPELSHASL 368
           T   +P   P   +  P A VP   P  + +T      T P   +PL        S  + 
Sbjct: 348 TSTTAPTFQPVFSSMGPPASVPLPAPFFKQTT---TPATAPTTTAPLFTGLASATSAVAP 404

Query: 369 IANQSPFRAPLNVTNTAGTSLPSVDLLQKLRLTPQHDQIQTQPLGKG---AMVASFSPAA 425
           I + SP     +     G  + SV     +  T       +QP   G   A  ASF+PA 
Sbjct: 405 ITSASPSTDSAS-KPAFGFGINSVS-SSSVSTTTSTATAASQPFLFGAPQASAASFTPAM 462

Query: 426 GQLATPESFIEPPSKTAAARVAA-SASLSNMVLAPLQSMQQNQDPEVFVQPKVLSSAIQV 484
           G +     F +PP+      V   S SL   V  P  +     D   F            
Sbjct: 463 GSIF---QFGKPPALPTTTTVTTFSQSLPTAV--PTATSSSAADFSGF------------ 505

Query: 485 AGAPLVTATTTAVSSVLLAPSVFQQTVTRSSDLERKASSPSPL 527
            G+ L T+     S   L    F  T T + ++   +S+ SPL
Sbjct: 506 -GSTLATSAPATSSQPTL---TFSNTSTPTFNIPFGSSAKSPL 544


>gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]
          Length = 5765

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 59/280 (21%), Positives = 108/280 (38%), Gaps = 40/280 (14%)

Query: 273  TLGVPSAAHHS--VQPEITTPVLITPASITQSNEKHAPTYTIPLSPVLSPTL--PAEAPT 328
            ++  PS++  +    P +TT      A+ + +N    P  T P++PVL+ T   PA   +
Sbjct: 4666 SMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPG-TTPITPVLTSTATTPAATSS 4724

Query: 329  AQVPPSLPRNSTMMQAVKTTPRQRSPLLNQPVPELSHASLIANQSPFRAPLNVTNTAGTS 388
                 S PR +T +  + +T  + +     P+P  +  +     +    P++  +T  TS
Sbjct: 4725 KATSSSSPRTATTLPVLTSTATKSTATSFTPIPSSTLWTTWTVPAQTTTPMSTMSTIHTS 4784

Query: 389  LPSVDLLQKLRLTPQHDQIQTQPLGKGAMVASFSPAAGQLATPESF-----IEPPSKTAA 443
                        TP+     T         A+ + A    ATP S      I     T A
Sbjct: 4785 -----------STPETTHTSTVL----TTTATMTRATNSTATPSSTLGTTRILTELTTTA 4829

Query: 444  ARVAASASLSNMVLAPLQSMQQNQDPEVFVQPKVLSSAIQVAGAPLVTATTTAVSSVLLA 503
               AA+ S + +   P  +        +  +P  +++ +   G+   TAT ++       
Sbjct: 4830 TTTAATGSTATLSSTPGTTW-------ILTEPSTIATVMVPTGS---TATASSTLGTAHT 4879

Query: 504  PSVFQQTVTRSSDLERKASSPSPLTIGTPESQRKPSIILS 543
            P V   T   +      ++ PS  T+GT    R P+++ S
Sbjct: 4880 PKVV--TTMATMPTATASTVPSSSTVGT---TRTPAVLPS 4914



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 68/319 (21%), Positives = 111/319 (34%), Gaps = 42/319 (13%)

Query: 269  PQSETLGVPSAAHHSVQPEITTPVLITPASITQSNEKHAPTYTIPLSP-----VLSPTLP 323
            P + +   PS+   +    I T    T  +   +     PT T+  +P       + T P
Sbjct: 1892 PATSSTATPSSTPGTTW--ILTKPTTTATTTASTGSTATPTSTLRTAPPPKVLTTTATTP 1949

Query: 324  AEAPTAQVPPSLPRNSTMMQAVKTTPRQRSPLLNQPVPELSHASLIANQSPFRAPLNVTN 383
                +   P S P  +T + A+++T    +     P+P  S  +     S    P   T 
Sbjct: 1950 TVTSSKATPSSSPGTATALPALRSTATTPTATSVTPIPSSSLGTTWTRLSQTTTP---TA 2006

Query: 384  TAGTSLPSVDLLQKLRLTPQHDQIQTQPLGKGAMVASFSPAAGQLATPES------FIEP 437
            T  T+ PS         TP+     T         A+ + A G +ATP S        + 
Sbjct: 2007 TMSTATPS--------STPETAHTSTVL----TATATTTGATGSVATPSSTPGTAHTTKV 2054

Query: 438  PSKTAAARVAASASLSNMVLAPLQSMQQNQDPEV---FVQPKVLSSAIQVAGAPLVTATT 494
            P+ T     A  +S     L P   +     P      V P  +      A   L T TT
Sbjct: 2055 PTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTA-TVLTTTTT 2113

Query: 495  TAVSSVLLAPSVFQQT-------VTRSSDLERKASSPSPLTIGTPESQRKPSIILSKSQL 547
            T  +  +  PS   QT        T ++ +    S+ +P +  TP +   P ++ + +  
Sbjct: 2114 TVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSS--TPGTTPIPPVLTTTATT 2171

Query: 548  QDTLIHLIKNDSSFLSTLH 566
                 + +   SS L T H
Sbjct: 2172 PAATSNTV-TPSSALGTTH 2189



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 70/284 (24%), Positives = 98/284 (34%), Gaps = 58/284 (20%)

Query: 263  EQLGGAPQSETLG---VPSAAHHSVQP-EITTPVLITPASITQSNEKHAPTYTIPLSPVL 318
            EQ   A  + T G   +PS+   +  P ++ T    TP + +      +   T    PVL
Sbjct: 2998 EQTTAATTTATTGSTAIPSSTPGTAPPPKVLTSTATTPTATSSKATSSSSPRTATTLPVL 3057

Query: 319  SPTLPAEAPTAQVP-PS--LPRNSTMMQAVKTTPRQRSPLLNQPVPELSHASLIANQSPF 375
            + T      T+  P PS  L    T+ +   T     S +     PE +H S +      
Sbjct: 3058 TSTATKSTATSFTPIPSFTLGTTGTLPEQTTTPMATMSTIHPSSTPETTHTSTVLTTK-- 3115

Query: 376  RAPLNVTNTAGTSLPSVDLLQKLRLTPQHDQIQTQPLGKGAMVASFSPAAGQLATPES-- 433
                  T T  TS  S         TP      T  L +    A+ + A G  ATP S  
Sbjct: 3116 -----ATTTRATSSMS---------TPSSTPGTTWILTELTTAATTTAATGPTATPSSTP 3161

Query: 434  ----FIEPPSKTAAARV----AASASLSNMVLAPLQSMQQNQDPEVFVQPKVLSSAIQVA 485
                 +  PS TA   V     A+AS +      L               KVL+S     
Sbjct: 3162 GTTWILTEPSTTATVTVPTGSTATASSTRATAGTL---------------KVLTS----- 3201

Query: 486  GAPLVTATTTAVSSVLLAPSVFQQTVTRSSDLERKASSPSPLTI 529
                 TATT  V S    PS    T T    L   A++P+  ++
Sbjct: 3202 -----TATTPTVISSRATPSSSPGTATALPALRSTATTPTATSV 3240



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 66/271 (24%), Positives = 95/271 (35%), Gaps = 30/271 (11%)

Query: 273  TLGVPSAAHHSVQPEITTP--VLITPASITQSNEKHAPTYTIPLSPVLSPTLPAEAPTAQ 330
            T    S A  S  P    P  VL +PA+   +    A + + P +    P L + A  + 
Sbjct: 4263 TASTGSTATPSSTPGTAPPPKVLTSPATTPTATSSKATSSSSPRTATTLPVLTSTATKST 4322

Query: 331  VPPSLPRNSTMMQAVKTTPRQ-------RSPLLNQPVPELSHASLIANQSPFRAPLNVTN 383
                 P  S+ +    T P Q        S +     PE +H S +              
Sbjct: 4323 ATSVTPIPSSTLGTTGTLPEQTTTPVATMSTIHPSSTPETTHTSTVLTTK----ATTTRA 4378

Query: 384  TAGTSLPSVDLLQKLRLTPQHDQIQTQPLGKGAMVASFSPAAGQLATP-ESFIEPPSKTA 442
            T+ TS PS         TP    I T+        A+  P A   +TP  ++I     T 
Sbjct: 4379 TSSTSTPS--------STPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTELTTT 4430

Query: 443  AARVAASASLSNMVLAPLQS---MQQNQDPEVFV---QPKVLSSAIQVAGAPLV--TATT 494
            A   A++ S +     P  +    + +    V V        SS    AG P V  TATT
Sbjct: 4431 ATTTASTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATT 4490

Query: 495  TAVSSVLLAPSVFQQTVTRSSDLERKASSPS 525
              V+S    PS    T T    L   A++P+
Sbjct: 4491 PTVTSSKATPSSSPGTATALPALRSTATTPT 4521



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 59/281 (20%), Positives = 89/281 (31%), Gaps = 22/281 (7%)

Query: 273  TLGVPS---AAHHSVQPEITTPVLITPASITQSNEKHAPTYTIPLSPVLSPTLPAEA--P 327
            T+ VP+   A   S Q    TP + T A+        A  ++ P +    P L + A  P
Sbjct: 3733 TVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTP 3792

Query: 328  TAQVPPSLPRNS-----TMMQAVKTTPRQRSPLLNQPVPELSHASLIANQSP-------- 374
            TA    ++P +S     T +    T     S       PE +H S +   +         
Sbjct: 3793 TATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTTATTTRATGS 3852

Query: 375  FRAPLNVTNTAGTSLPSVDLLQKLRLTPQHDQIQTQPLGKGAMVASFSPAAGQLATPESF 434
               P +   TA T+           +TP       +         +    +G   TP S 
Sbjct: 3853 VATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGSTVTPSSV 3912

Query: 435  IEPPSKTAAARVAASASLSNMVLAPLQSMQQNQDPEVFVQPKVLSSAIQVAGAPLVTATT 494
                          +   +  +  P  S Q +  P   +      +A      P  T  T
Sbjct: 3913 PGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPSLITTATTITATGSTTNPSSTPGT 3972

Query: 495  TAVSSVLLA----PSVFQQTVTRSSDLERKASSPSPLTIGT 531
            T +  VL      P+    TVT SS L    + P P T  T
Sbjct: 3973 TPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTAT 4013



 Score = 38.9 bits (89), Expect = 0.013
 Identities = 58/258 (22%), Positives = 84/258 (32%), Gaps = 35/258 (13%)

Query: 289  TTPVLITPASITQSNEKHAPTYTIPLSPVLSPTLPAEAPTAQVPPSLPRNSTMMQAVKTT 348
            TTP   T  S+T        T    LS   +PT      T    P     ST++ A  TT
Sbjct: 1976 TTP---TATSVTPIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTATATT 2032

Query: 349  PRQRSPLLN-QPVPELSHASLIANQSPFRAPLNVTNTAGTSLPSVDLLQKLRLTPQHDQI 407
                  +      P  +H + +   +        +++ GT+L            P     
Sbjct: 2033 TGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTP----------PVWIST 2082

Query: 408  QTQPLGKGAMVASFSPAAGQLATPESFIEPPSKTAAARVAASASLS---NMVLAPLQSMQ 464
             T P  +G+ V           TP S    P  T  A V  + + +     +  P  S Q
Sbjct: 2083 TTTPTTRGSTV-----------TPSSI---PGTTHTATVLTTTTTTVATGSMATPSSSTQ 2128

Query: 465  QNQDPEVFVQPKVLSSAIQVAGAPLVTATTTAVSSVLLA----PSVFQQTVTRSSDLERK 520
             +  P          +A      P  T  TT +  VL      P+    TVT SS L   
Sbjct: 2129 TSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSNTVTPSSALGTT 2188

Query: 521  ASSPSPLTIGTPESQRKP 538
             + P P T+ T   +  P
Sbjct: 2189 HTPPVPNTMATTHGRSLP 2206



 Score = 38.9 bits (89), Expect = 0.013
 Identities = 60/281 (21%), Positives = 86/281 (30%), Gaps = 22/281 (7%)

Query: 273  TLGVPS---AAHHSVQPEITTPVLITPASITQSNEKHAPTYTIPLSPVLSPTLPAEA--P 327
            T+ VP+   A   S Q    TP + T A+        A  ++ P +    P L + A  P
Sbjct: 2476 TVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTP 2535

Query: 328  TAQVPPSLPRNS-----TMMQAVKTTPRQRSPLLNQPVPELSHASLIANQSP-------- 374
            TA    ++P +S     T +    T     S       PE  H S +   +         
Sbjct: 2536 TATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTATTTGATGS 2595

Query: 375  FRAPLNVTNTAGTSLPSVDLLQKLRLTPQHDQIQTQPLGKGAMVASFSPAAGQLATPESF 434
               P +   TA T+            TP       + L       +     G   TP S 
Sbjct: 2596 VATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGTARTLPVWISTTTTPTTRGSTVTPSSI 2655

Query: 435  IEPPSKTAAARVAASASLSNMVLAPLQSMQQNQDPEVFVQPKVLSSAIQVAGAPLVTATT 494
                          +   +  +  P  S Q +  P          +A      P  T  T
Sbjct: 2656 PGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGT 2715

Query: 495  TAVSSVLLA----PSVFQQTVTRSSDLERKASSPSPLTIGT 531
            T +  VL      P+    TVT SS L    + P P T  T
Sbjct: 2716 TPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTAT 2756



 Score = 38.9 bits (89), Expect = 0.013
 Identities = 58/258 (22%), Positives = 83/258 (32%), Gaps = 35/258 (13%)

Query: 289  TTPVLITPASITQSNEKHAPTYTIPLSPVLSPTLPAEAPTAQVPPSLPRNSTMMQAVKTT 348
            TTP   T  S+T        T    LS   +PT      T    P     ST++    TT
Sbjct: 3233 TTP---TATSVTAIPSSSLGTAWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTTTT 3289

Query: 349  PRQRSPLLN-QPVPELSHASLIANQSPFRAPLNVTNTAGTSLPSVDLLQKLRLTPQHDQI 407
             R    +      P  +H + +   +        +++ GT+L            P     
Sbjct: 3290 TRATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTP----------PVWIST 3339

Query: 408  QTQPLGKGAMVASFSPAAGQLATPESFIEPPSKTAAARVAASASLS---NMVLAPLQSMQ 464
             T P  +G+ V           TP S    P  T  A V  + + +     +  P  S Q
Sbjct: 3340 TTTPTTRGSTV-----------TPSSI---PGTTHTATVLTTTTTTVATGSMATPSSSTQ 3385

Query: 465  QNQDPEVFVQPKVLSSAIQVAGAPLVTATTTAVSSVLLA----PSVFQQTVTRSSDLERK 520
             +  P          +A      P  T  TT +  VL      P+    TVT SS L   
Sbjct: 3386 TSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTT 3445

Query: 521  ASSPSPLTIGTPESQRKP 538
             + P P T  T   +  P
Sbjct: 3446 HTPPVPNTTATTHGRSLP 3463



 Score = 38.1 bits (87), Expect = 0.022
 Identities = 58/266 (21%), Positives = 96/266 (36%), Gaps = 32/266 (12%)

Query: 285  QPEITTPVLITPASITQSNEKHAPTYTIPLSPVLSPTLPAEAPTAQVPPSLPRNSTMMQA 344
            +P  T  V +   S   ++   A   T  +S   + T P    +   P S P  +T + A
Sbjct: 3727 EPSTTATVTVPTGSTATASSTQATAGTPHVST--TATTPTVTSSKATPFSSPGTATALPA 3784

Query: 345  VKTTPRQRSPLLNQPVPELSHASLIANQSPFRAPLNVTNTAGTSLPSVDLLQKLRLTPQH 404
            +++T    +      +P  S  +     S    P   T T  T+ PS         TP+ 
Sbjct: 3785 LRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTP---TATMSTATPSS--------TPET 3833

Query: 405  DQIQTQPLGKGAMVASFSPAAGQLATPESFIEPPSKTAAARVAASASLSNMVLAPLQSMQ 464
                T         A+ + A G +ATP S       TA      + + +   + P  S  
Sbjct: 3834 AHTSTVL----TTTATTTRATGSVATPSS----TPGTAHTTKVPTTTTTGFTVTPSSSPG 3885

Query: 465  QNQDPEVFVQPKVLSSAIQVAGAPLVTATTTAVSSVLLAPSVFQQTVTRSSDLERKASSP 524
              + P V++      +    +G+   T T ++V      P+V   T T  +       S 
Sbjct: 3886 TARTPPVWISTTTTPTT---SGS---TVTPSSVPGTTHTPTVLTTTTTTVATGSMATPSS 3939

Query: 525  SPLTIGTPESQRKPSIILSKSQLQDT 550
            S  T GTP     PS+I + + +  T
Sbjct: 3940 STQTSGTP-----PSLITTATTITAT 3960



 Score = 35.0 bits (79), Expect = 0.19
 Identities = 23/71 (32%), Positives = 31/71 (43%), Gaps = 6/71 (8%)

Query: 295  TPASITQSNEKHAPTYTI------PLSPVLSPTLPAEAPTAQVPPSLPRNSTMMQAVKTT 348
            T A  T +  +  PT T       PL+  L+PTL +E  T+Q   S PR  T M  +  T
Sbjct: 1719 TLAPTTMATSRARPTGTASTASKEPLTTSLAPTLTSELSTSQAETSTPRTETTMSPLTNT 1778

Query: 349  PRQRSPLLNQP 359
               +     QP
Sbjct: 1779 TTSQGTTRCQP 1789



 Score = 33.1 bits (74), Expect = 0.72
 Identities = 51/241 (21%), Positives = 80/241 (33%), Gaps = 12/241 (4%)

Query: 277  PSAAHHSVQPEITTPVLITPASITQSNEKHAPTYTIPLSPVLSPTLPAEAPTAQVPPSLP 336
            P  AH +  P  TT       S +       P + I  +   + T P  + +   P S+P
Sbjct: 4588 PGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVW-ISTTTTPTTTTPTTSGSTVTPSSIP 4646

Query: 337  RNSTMMQAVKTTPRQRSPLLNQPVPELSHASLIANQSPFRAPLNVTNTAGTSLPSVDLLQ 396
              +T    V TT        +   P  S  +     S       +T T  T+ PS     
Sbjct: 4647 -GTTHTARVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPS----- 4700

Query: 397  KLRLTPQHDQIQTQPLGKGAMVASFSPAAGQLATPESFIEPPSKTAAARVAASASLSNMV 456
                TP    I           A+ S  A   ++P +    P  T+ A  + + S + + 
Sbjct: 4701 ---STPGTTPITPVLTSTATTPAATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIP 4757

Query: 457  LAPLQSMQQNQDPEVFVQPKVLSSAIQVAGAPLVTATTTAVSSVLLAPSVFQQTVTRSSD 516
             + L +      P     P    S I  +  P  T T+T +++          T T SS 
Sbjct: 4758 SSTLWTTW--TVPAQTTTPMSTMSTIHTSSTPETTHTSTVLTTTATMTRATNSTATPSST 4815

Query: 517  L 517
            L
Sbjct: 4816 L 4816



 Score = 31.6 bits (70), Expect = 2.1
 Identities = 53/250 (21%), Positives = 86/250 (34%), Gaps = 27/250 (10%)

Query: 285  QPEITTPVLITPASITQSNEKHAPTYTIPLSPVLSPTLPAEAPTAQVPPSLPRNSTMMQA 344
            +P  T  V +   S   ++   A   T  +S   + T P    +   P S P  +T + A
Sbjct: 2470 EPSTTATVTVPTGSTATASSTQATAGTPHVST--TATTPTVTSSKATPFSSPGTATALPA 2527

Query: 345  VKTTPRQRSPLLNQPVPELSHASLIANQSPFRAPLNVTNTAGTSLPSVDLLQKLRLTPQH 404
            +++T    +      +P  S  +     S    P   T T  T+ PS         TP+ 
Sbjct: 2528 LRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTP---TATMSTATPSS--------TPET 2576

Query: 405  DQIQTQPLGKGAMVASFSPAAGQLATPESFIEPPSKTAAARVAASASLSNMVLAPLQSMQ 464
                T         A+ + A G +ATP S       TA      + + +     P  S  
Sbjct: 2577 VHTSTVL----TTTATTTGATGSVATPSS----TPGTAHTTKVLTTTTTGFTATPSSSPG 2628

Query: 465  QNQDPEVFVQPKVLSSAIQVAGAPLVTATTTAVSSVLLAPSVFQQTVTRSSDLERKASSP 524
              +   V++      +     G+   T T +++      P+V   T T  +       S 
Sbjct: 2629 TARTLPVWISTTTTPTT---RGS---TVTPSSIPGTTHTPTVLTTTTTTVATGSMATPSS 2682

Query: 525  SPLTIGTPES 534
            S  T GTP S
Sbjct: 2683 STQTSGTPPS 2692


>gi|222352122 hypothetical protein LOC284297 [Homo sapiens]
          Length = 1573

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 72/286 (25%), Positives = 96/286 (33%), Gaps = 50/286 (17%)

Query: 269  PQSETLGVPSAAHHSVQPEITTPVLITPASITQSNEKHAPTYTIPLSPVLSPTLPA-EAP 327
            P   T   P+    S  P ITT  L T      S+   APT    L P L+ T PA    
Sbjct: 1317 PDPTTTPHPTTPDPSSTPVITTVSLPTSLGTELSSPTLAPTVKPSLHPQLTFTAPAPHTS 1376

Query: 328  TAQVP-----------PSLPRNSTMMQAVKT----TPRQRSPLLNQPVPELSHASLIANQ 372
            T+Q+P           PS    +T M  + T     PR +SP L  P     H++     
Sbjct: 1377 TSQIPTLEPSPALESSPSRSSTATSMDPLSTEDFKPPRSQSPNLTPPPTHTPHSASDLTV 1436

Query: 373  SPFRAPLNVTNTAGTSLPSVDLLQKLRLTPQHDQIQTQPLGKGAMVASFSPAAGQLATPE 432
            SP   PL          P +D    L L P   Q    P   G  VA   P       P 
Sbjct: 1437 SP--DPLLSPTAHPLDHPPLD---PLTLGPTPGQ---SPGPHGPCVAPTPPVRVMACEPP 1488

Query: 433  SFIEPPSKTAAARVAASASLSNMVLAPLQSMQQNQDPEVFVQPKVLSSAIQVAGAPLVTA 492
            + +E      AA       L  +     Q  Q+ Q             A+ +    LV A
Sbjct: 1489 ALVE----LVAAVRDVGGQLQRLTQVVEQERQERQ-------------ALLLGLTQLVEA 1531

Query: 493  TTTAVSSVLLAPSVFQQTVTRSSDLERKASSPSPLTIGTPESQRKP 538
                            + V R +++    S P+P T  TPE + +P
Sbjct: 1532 AR--------GLGQLGEAVKRLAEMAWTTSMPAPTTT-TPEEEERP 1568



 Score = 32.7 bits (73), Expect = 0.94
 Identities = 67/307 (21%), Positives = 101/307 (32%), Gaps = 35/307 (11%)

Query: 185  PSTQLSNLGSTETLEEMPSGSQDKSAPSGHKHLTVEELFGTSLPKEQPAVVGLDSEEMER 244
            PST       + T E++P         +     TV E   +  P   P         M  
Sbjct: 1102 PSTPSEVTSLSPTSEQVPESDTTPDLDTTPYSSTVSEYSRSPDPSPSPHPTTTPDPTMA- 1160

Query: 245  LPGDASQKEPNSFLPFPFEQLGGAPQSETLGVPSAAHHS--VQPEITTPVLITPASITQS 302
             P   +   P     FP       P   T   P+   HS  +    TTP   T  +IT S
Sbjct: 1161 -PDPITTLNPTVTPHFPT-----TPHPTTTPHPTTITHSTMIPDPTTTPQPFT--TITHS 1212

Query: 303  NEKHAPTYT----IPLSPVLSPTLPAEAPTAQVPPSLPRNSTMMQAVKTTPRQRSPLLNQ 358
                 PT T      + P  +P      PT    P+   +STM+    TTP+  + +   
Sbjct: 1213 TMIPDPTTTPQPFTTMQPTTTPHSTTPHPTTTPHPTTITHSTMIPDPTTTPQPFTTMQPT 1272

Query: 359  PVPELSHASLIANQSPFRAPLNVTNTAGTSLPSVDLLQKLRLTPQHDQIQTQPLGKGAMV 418
             +P            P   P   T    T+ P         +TP      T P       
Sbjct: 1273 TMPH-----------PTTTPHPTTTPHPTTTPHPTTTPHPTMTPDP---TTTPYPTTTPD 1318

Query: 419  ASFSPAAGQLATPESFIEPPSKTAAARVAASASLSNMVLAPLQSMQQNQDPEV-FVQPKV 477
             + +P      TP+    P   T +   +    LS+  LAP  +++ +  P++ F  P  
Sbjct: 1319 PTTTP---HPTTPDPSSTPVITTVSLPTSLGTELSSPTLAP--TVKPSLHPQLTFTAPAP 1373

Query: 478  LSSAIQV 484
             +S  Q+
Sbjct: 1374 HTSTSQI 1380


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 65/303 (21%), Positives = 122/303 (40%), Gaps = 38/303 (12%)

Query: 127  EEETRRSQQAARDKQSPSQANGC-SDHRPIDILEMLSRAKDEYERNQMGDSNISSPGLQP 185
            E+ T RS  + R +   S      +D    D  +M +R++ +    + GDS   +   +P
Sbjct: 3450 EDATDRSYVSRRRRTKKSVDTSVQTDDEDQDEWDMPTRSRRKARVGKYGDSMTEADKTKP 3509

Query: 186  STQLSNLGSTETLEEM-----PSGSQDKSAPSGHKHLTVEELFGTSLPKEQPAVVGL--- 237
             +++S++ + +T+ E+     P G+    +        VE +   S P++      L   
Sbjct: 3510 LSKVSSI-AVQTVAEISVQTEPVGTIRTPSIRARVDAKVEIIKHISAPEKTYKGGSLGCQ 3568

Query: 238  -----DSEEMERLPGDASQKEPNSFLPFPFEQLGGAPQSETLGVPSAAHHSVQPEITTPV 292
                 D++  + L   +  K+     P P E       S  L   S    +  P  +  V
Sbjct: 3569 TEADSDTQSPQYLSATSPPKDKKR--PTPLE----IGYSSHLRADSTVQLAPSPPKSPKV 3622

Query: 293  L---ITPASITQSNEKHAPTYTIPLSPVLSPTLPAEAPTAQVPPSLPRNSTMMQAVKTTP 349
            L   I+P S  ++ E     Y  PL   +SP        A+VPP+ P+ + MMQ   + P
Sbjct: 3623 LYSPISPLSPGKALESAFVPYEKPLPDDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDP 3682

Query: 350  RQRSPLLNQPVPELSHASLIANQSPFRAPLNVTNTAGTSLPSVDLLQKLRLT---PQHDQ 406
            +  SP  ++           ++++PF+     T     ++ S    +K++ T   P  ++
Sbjct: 3683 KPLSPTADE-----------SSRAPFQYTEGYTTKGSQTMTSSGAQKKVKRTLPNPPPEE 3731

Query: 407  IQT 409
            I T
Sbjct: 3732 IST 3734



 Score = 30.0 bits (66), Expect = 6.1
 Identities = 31/133 (23%), Positives = 55/133 (41%), Gaps = 23/133 (17%)

Query: 401  TPQHDQI---QTQPLGKGAMVASFSPAAGQLATPESFIEPPSKTAAARVAASASLSNMVL 457
            T  H Q+   QTQP  +     SF+P      TP+   + PS+              MV+
Sbjct: 3913 TLYHQQVSPYQTQPTFQAVATMSFTPQVQPTPTPQPSYQLPSQM-------------MVI 3959

Query: 458  APLQSMQQNQDPEVFVQPKVLSSAIQVAGAPLVTA--TTTAVSSVLLAPSVFQQTVTRSS 515
                  Q+ +   ++++PK+ S+   +   PL+ A  +T    +V    S +     R  
Sbjct: 3960 -----QQKPRQTTLYLEPKITSNYEVIRNQPLMIAPVSTDNTFAVSHLGSKYNSLDLRIG 4014

Query: 516  DLERKASSPSPLT 528
              ER + + SP++
Sbjct: 4015 LEERSSMASSPIS 4027


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.126    0.353 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,168,681
Number of Sequences: 37866
Number of extensions: 1198332
Number of successful extensions: 5129
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 44
Number of HSP's successfully gapped in prelim test: 338
Number of HSP's that attempted gapping in prelim test: 4216
Number of HSP's gapped (non-prelim): 940
length of query: 582
length of database: 18,247,518
effective HSP length: 108
effective length of query: 474
effective length of database: 14,157,990
effective search space: 6710887260
effective search space used: 6710887260
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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