BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|84043967 REV1-like isoform 2 [Homo sapiens] (1250 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|84043967 REV1-like isoform 2 [Homo sapiens] 2507 0.0 gi|7706681 REV1-like isoform 1 [Homo sapiens] 2503 0.0 gi|154350220 DNA polymerase iota [Homo sapiens] 99 3e-20 gi|7705344 DNA-directed DNA polymerase kappa [Homo sapiens] 96 2e-19 gi|5729982 DNA-directed DNA polymerase eta [Homo sapiens] 69 2e-11 gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens] 40 0.011 gi|195972857 Rho/Rac guanine nucleotide exchange factor 18 isofo... 38 0.053 gi|41327769 Rho/Rac guanine nucleotide exchange factor 18 isofor... 38 0.053 gi|236462242 potassium voltage-gated channel, KQT-like subfamily... 38 0.069 gi|236462079 potassium voltage-gated channel, KQT-like subfamily... 38 0.069 gi|236461942 potassium voltage-gated channel, KQT-like subfamily... 38 0.069 gi|236461719 potassium voltage-gated channel, KQT-like subfamily... 38 0.069 gi|28373065 potassium voltage-gated channel, KQT-like subfamily,... 38 0.069 gi|194440660 topoisomerase (DNA) II binding protein 1 [Homo sapi... 38 0.069 gi|150170670 piccolo isoform 2 [Homo sapiens] 35 0.34 gi|150378539 piccolo isoform 1 [Homo sapiens] 35 0.34 gi|110611228 utrophin [Homo sapiens] 35 0.45 gi|7657218 bromodomain-containing protein 4 isoform short [Homo ... 35 0.59 gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 35 0.59 gi|239757877 PREDICTED: FERM and PDZ domain containing 3 [Homo s... 34 0.76 gi|89060961 PREDICTED: FERM and PDZ domain containing 3 [Homo sa... 34 0.76 gi|89059963 PREDICTED: FERM and PDZ domain containing 3 [Homo sa... 34 0.76 gi|83367077 mucin 16 [Homo sapiens] 34 1.00 gi|239754668 PREDICTED: mucin 12 [Homo sapiens] 34 1.00 gi|239749217 PREDICTED: similar to Mucin-12, partial [Homo sapiens] 34 1.00 gi|239743293 PREDICTED: mucin 12 [Homo sapiens] 34 1.00 gi|239745855 PREDICTED: hypothetical protein XP_002343606 [Homo ... 33 1.3 gi|151301154 mucin 6, gastric [Homo sapiens] 33 1.7 gi|154091020 leucine-rich repeats and calponin homology (CH) dom... 33 2.2 gi|161016767 mucin 21 [Homo sapiens] 33 2.2 >gi|84043967 REV1-like isoform 2 [Homo sapiens] Length = 1250 Score = 2507 bits (6498), Expect = 0.0 Identities = 1250/1250 (100%), Positives = 1250/1250 (100%) Query: 1 MRRGGWRKRAENDGWETWGGYMAAKVQKLEEQFRSDAAMQKDGTSSTIFSGVAIYVNGYT 60 MRRGGWRKRAENDGWETWGGYMAAKVQKLEEQFRSDAAMQKDGTSSTIFSGVAIYVNGYT Sbjct: 1 MRRGGWRKRAENDGWETWGGYMAAKVQKLEEQFRSDAAMQKDGTSSTIFSGVAIYVNGYT 60 Query: 61 DPSAEELRKLMMLHGGQYHVYYSRSKTTHIIATNLPNAKIKELKGEKVIRPEWIVESIKA 120 DPSAEELRKLMMLHGGQYHVYYSRSKTTHIIATNLPNAKIKELKGEKVIRPEWIVESIKA Sbjct: 61 DPSAEELRKLMMLHGGQYHVYYSRSKTTHIIATNLPNAKIKELKGEKVIRPEWIVESIKA 120 Query: 121 GRLLSYIPYQLYTKQSSVQKGLSFNPVCRPEDPLPGPSNIAKQLNNRVNHIVKKIETENE 180 GRLLSYIPYQLYTKQSSVQKGLSFNPVCRPEDPLPGPSNIAKQLNNRVNHIVKKIETENE Sbjct: 121 GRLLSYIPYQLYTKQSSVQKGLSFNPVCRPEDPLPGPSNIAKQLNNRVNHIVKKIETENE 180 Query: 181 VKVNGMNSWNEEDENNDFSFVDLEQTSPGRKQNGIPHPRGSTAIFNGHTPSSNGALKTQD 240 VKVNGMNSWNEEDENNDFSFVDLEQTSPGRKQNGIPHPRGSTAIFNGHTPSSNGALKTQD Sbjct: 181 VKVNGMNSWNEEDENNDFSFVDLEQTSPGRKQNGIPHPRGSTAIFNGHTPSSNGALKTQD 240 Query: 241 CLVPMVNSVASRLSPAFSQEEDKAEKSSTDFRDCTLQQLQQSTRNTDALRNPHRTNSFSL 300 CLVPMVNSVASRLSPAFSQEEDKAEKSSTDFRDCTLQQLQQSTRNTDALRNPHRTNSFSL Sbjct: 241 CLVPMVNSVASRLSPAFSQEEDKAEKSSTDFRDCTLQQLQQSTRNTDALRNPHRTNSFSL 300 Query: 301 SPLHSNTKINGAHHSTVQGPSSTKSTSSVSTFSKAAPSVPSKPSDCNFISNFYSHSRLHH 360 SPLHSNTKINGAHHSTVQGPSSTKSTSSVSTFSKAAPSVPSKPSDCNFISNFYSHSRLHH Sbjct: 301 SPLHSNTKINGAHHSTVQGPSSTKSTSSVSTFSKAAPSVPSKPSDCNFISNFYSHSRLHH 360 Query: 361 ISMWKCELTEFVNTLQRQSNGIFPGREKLKKMKTGRSALVVTDTGDMSVLNSPRHQSCIM 420 ISMWKCELTEFVNTLQRQSNGIFPGREKLKKMKTGRSALVVTDTGDMSVLNSPRHQSCIM Sbjct: 361 ISMWKCELTEFVNTLQRQSNGIFPGREKLKKMKTGRSALVVTDTGDMSVLNSPRHQSCIM 420 Query: 421 HVDMDCFFVSVGIRNRPDLKGKPVAVTSNRGTGRAPLRPGANPQLEWQYYQNKILKGKAD 480 HVDMDCFFVSVGIRNRPDLKGKPVAVTSNRGTGRAPLRPGANPQLEWQYYQNKILKGKAD Sbjct: 421 HVDMDCFFVSVGIRNRPDLKGKPVAVTSNRGTGRAPLRPGANPQLEWQYYQNKILKGKAD 480 Query: 481 IPDSSLWENPDSAQANGIDSVLSRAEIASCSYEARQLGIKNGMFFGHAKQLCPNLQAVPY 540 IPDSSLWENPDSAQANGIDSVLSRAEIASCSYEARQLGIKNGMFFGHAKQLCPNLQAVPY Sbjct: 481 IPDSSLWENPDSAQANGIDSVLSRAEIASCSYEARQLGIKNGMFFGHAKQLCPNLQAVPY 540 Query: 541 DFHAYKEVAQTLYETLASYTHNIEAVSCDEALVDITEILAETKLTPDEFANAVRMEIKDQ 600 DFHAYKEVAQTLYETLASYTHNIEAVSCDEALVDITEILAETKLTPDEFANAVRMEIKDQ Sbjct: 541 DFHAYKEVAQTLYETLASYTHNIEAVSCDEALVDITEILAETKLTPDEFANAVRMEIKDQ 600 Query: 601 TKCAASVGIGSNILLARMATRKAKPDGQYHLKPEEVDDFIRGQLVTNLPGVGHSMESKLA 660 TKCAASVGIGSNILLARMATRKAKPDGQYHLKPEEVDDFIRGQLVTNLPGVGHSMESKLA Sbjct: 601 TKCAASVGIGSNILLARMATRKAKPDGQYHLKPEEVDDFIRGQLVTNLPGVGHSMESKLA 660 Query: 661 SLGIKTCGDLQYMTMAKLQKEFGPKTGQMLYRFCRGLDDRPVRTEKERKSVSAEINYGIR 720 SLGIKTCGDLQYMTMAKLQKEFGPKTGQMLYRFCRGLDDRPVRTEKERKSVSAEINYGIR Sbjct: 661 SLGIKTCGDLQYMTMAKLQKEFGPKTGQMLYRFCRGLDDRPVRTEKERKSVSAEINYGIR 720 Query: 721 FTQPKEAEAFLLSLSEEIQRRLEATGMKGKRLTLKIMVRKPGAPVETAKFGGHGICDNIA 780 FTQPKEAEAFLLSLSEEIQRRLEATGMKGKRLTLKIMVRKPGAPVETAKFGGHGICDNIA Sbjct: 721 FTQPKEAEAFLLSLSEEIQRRLEATGMKGKRLTLKIMVRKPGAPVETAKFGGHGICDNIA 780 Query: 781 RTVTLDQATDNAKIIGKAMLNMFHTMKLNISDMRGVGIHVNQLVPTNLNPSTCPSRPSVQ 840 RTVTLDQATDNAKIIGKAMLNMFHTMKLNISDMRGVGIHVNQLVPTNLNPSTCPSRPSVQ Sbjct: 781 RTVTLDQATDNAKIIGKAMLNMFHTMKLNISDMRGVGIHVNQLVPTNLNPSTCPSRPSVQ 840 Query: 841 SSHFPSGSYSVRDVFQVQKAKKSTEEEHKEVFRAAVDLEISSASRTCTFLPPFPAHLPTS 900 SSHFPSGSYSVRDVFQVQKAKKSTEEEHKEVFRAAVDLEISSASRTCTFLPPFPAHLPTS Sbjct: 841 SSHFPSGSYSVRDVFQVQKAKKSTEEEHKEVFRAAVDLEISSASRTCTFLPPFPAHLPTS 900 Query: 901 PDTNKAESSGKWNGLHTPVSVQSRLNLSIEVPSPSQLDQSVLEALPPDLREQVEQVCAVQ 960 PDTNKAESSGKWNGLHTPVSVQSRLNLSIEVPSPSQLDQSVLEALPPDLREQVEQVCAVQ Sbjct: 901 PDTNKAESSGKWNGLHTPVSVQSRLNLSIEVPSPSQLDQSVLEALPPDLREQVEQVCAVQ 960 Query: 961 QAESHGDKKKEPVNGCNTGILPQPVGTVLLQIPEPQESNSDAGINLIALPAFSQVDPEVF 1020 QAESHGDKKKEPVNGCNTGILPQPVGTVLLQIPEPQESNSDAGINLIALPAFSQVDPEVF Sbjct: 961 QAESHGDKKKEPVNGCNTGILPQPVGTVLLQIPEPQESNSDAGINLIALPAFSQVDPEVF 1020 Query: 1021 AALPAELQRELKAAYDQRQRQGENSTHQQSASASVPKNPLLHLKAAVKEKKRNKKKKTIG 1080 AALPAELQRELKAAYDQRQRQGENSTHQQSASASVPKNPLLHLKAAVKEKKRNKKKKTIG Sbjct: 1021 AALPAELQRELKAAYDQRQRQGENSTHQQSASASVPKNPLLHLKAAVKEKKRNKKKKTIG 1080 Query: 1081 SPKRIQSPLNNKLLNSPAKTLPGACGSPQKLIDGFLKHEGPPAEKPLEELSASTSGVPGL 1140 SPKRIQSPLNNKLLNSPAKTLPGACGSPQKLIDGFLKHEGPPAEKPLEELSASTSGVPGL Sbjct: 1081 SPKRIQSPLNNKLLNSPAKTLPGACGSPQKLIDGFLKHEGPPAEKPLEELSASTSGVPGL 1140 Query: 1141 SSLQSDPAGCVRPPAPNLAGAVEFNDVKTLLREWITTISDPMEEDILQVVKYCTDLIEEK 1200 SSLQSDPAGCVRPPAPNLAGAVEFNDVKTLLREWITTISDPMEEDILQVVKYCTDLIEEK Sbjct: 1141 SSLQSDPAGCVRPPAPNLAGAVEFNDVKTLLREWITTISDPMEEDILQVVKYCTDLIEEK 1200 Query: 1201 DLEKLDLVIKYMKRLMQQSVESVWNMAFDFILDNVQVVLQQTYGSTLKVT 1250 DLEKLDLVIKYMKRLMQQSVESVWNMAFDFILDNVQVVLQQTYGSTLKVT Sbjct: 1201 DLEKLDLVIKYMKRLMQQSVESVWNMAFDFILDNVQVVLQQTYGSTLKVT 1250 >gi|7706681 REV1-like isoform 1 [Homo sapiens] Length = 1251 Score = 2503 bits (6486), Expect = 0.0 Identities = 1250/1251 (99%), Positives = 1250/1251 (99%), Gaps = 1/1251 (0%) Query: 1 MRRGGWRKRAENDGWETWGGYMAAKVQKLEEQFRSDAAMQKDGTSSTIFSGVAIYVNGYT 60 MRRGGWRKRAENDGWETWGGYMAAKVQKLEEQFRSDAAMQKDGTSSTIFSGVAIYVNGYT Sbjct: 1 MRRGGWRKRAENDGWETWGGYMAAKVQKLEEQFRSDAAMQKDGTSSTIFSGVAIYVNGYT 60 Query: 61 DPSAEELRKLMMLHGGQYHVYYSRSKTTHIIATNLPNAKIKELKGEKVIRPEWIVESIKA 120 DPSAEELRKLMMLHGGQYHVYYSRSKTTHIIATNLPNAKIKELKGEKVIRPEWIVESIKA Sbjct: 61 DPSAEELRKLMMLHGGQYHVYYSRSKTTHIIATNLPNAKIKELKGEKVIRPEWIVESIKA 120 Query: 121 GRLLSYIPYQLYTKQSSVQKGLSFNPVCRPEDPLPGPSNIAKQLNNRVNHIVKKIETENE 180 GRLLSYIPYQLYTKQSSVQKGLSFNPVCRPEDPLPGPSNIAKQLNNRVNHIVKKIETENE Sbjct: 121 GRLLSYIPYQLYTKQSSVQKGLSFNPVCRPEDPLPGPSNIAKQLNNRVNHIVKKIETENE 180 Query: 181 VKVNGMNSWNEEDENNDFSFVDLEQTSPGRKQNGIPHPRGSTAIFNGHTPSSNGALKTQD 240 VKVNGMNSWNEEDENNDFSFVDLEQTSPGRKQNGIPHPRGSTAIFNGHTPSSNGALKTQD Sbjct: 181 VKVNGMNSWNEEDENNDFSFVDLEQTSPGRKQNGIPHPRGSTAIFNGHTPSSNGALKTQD 240 Query: 241 CLVPMVNSVASRLSPAFSQEEDKAEKSSTDFRDCTLQQLQQSTRNTDALRNPHRTNSFSL 300 CLVPMVNSVASRLSPAFSQEEDKAEKSSTDFRDCTLQQLQQSTRNTDALRNPHRTNSFSL Sbjct: 241 CLVPMVNSVASRLSPAFSQEEDKAEKSSTDFRDCTLQQLQQSTRNTDALRNPHRTNSFSL 300 Query: 301 SPLHSNTKINGAHHSTVQGPSSTKSTSSVSTFSKAAPSVPSKPSDCNFISNFYSHSRLHH 360 SPLHSNTKINGAHHSTVQGPSSTKSTSSVSTFSKAAPSVPSKPSDCNFISNFYSHSRLHH Sbjct: 301 SPLHSNTKINGAHHSTVQGPSSTKSTSSVSTFSKAAPSVPSKPSDCNFISNFYSHSRLHH 360 Query: 361 ISMWKCELTEFVNTLQRQSNGIFPGREKLKKMKTGRSALVVTDTGDMSVLNSPRHQSCIM 420 ISMWKCELTEFVNTLQRQSNGIFPGREKLKKMKTGRSALVVTDTGDMSVLNSPRHQSCIM Sbjct: 361 ISMWKCELTEFVNTLQRQSNGIFPGREKLKKMKTGRSALVVTDTGDMSVLNSPRHQSCIM 420 Query: 421 HVDMDCFFVSVGIRNRPDLKGKPVAVTSNRGTGRAPLRPGANPQLEWQYYQNKILKGKA- 479 HVDMDCFFVSVGIRNRPDLKGKPVAVTSNRGTGRAPLRPGANPQLEWQYYQNKILKGKA Sbjct: 421 HVDMDCFFVSVGIRNRPDLKGKPVAVTSNRGTGRAPLRPGANPQLEWQYYQNKILKGKAA 480 Query: 480 DIPDSSLWENPDSAQANGIDSVLSRAEIASCSYEARQLGIKNGMFFGHAKQLCPNLQAVP 539 DIPDSSLWENPDSAQANGIDSVLSRAEIASCSYEARQLGIKNGMFFGHAKQLCPNLQAVP Sbjct: 481 DIPDSSLWENPDSAQANGIDSVLSRAEIASCSYEARQLGIKNGMFFGHAKQLCPNLQAVP 540 Query: 540 YDFHAYKEVAQTLYETLASYTHNIEAVSCDEALVDITEILAETKLTPDEFANAVRMEIKD 599 YDFHAYKEVAQTLYETLASYTHNIEAVSCDEALVDITEILAETKLTPDEFANAVRMEIKD Sbjct: 541 YDFHAYKEVAQTLYETLASYTHNIEAVSCDEALVDITEILAETKLTPDEFANAVRMEIKD 600 Query: 600 QTKCAASVGIGSNILLARMATRKAKPDGQYHLKPEEVDDFIRGQLVTNLPGVGHSMESKL 659 QTKCAASVGIGSNILLARMATRKAKPDGQYHLKPEEVDDFIRGQLVTNLPGVGHSMESKL Sbjct: 601 QTKCAASVGIGSNILLARMATRKAKPDGQYHLKPEEVDDFIRGQLVTNLPGVGHSMESKL 660 Query: 660 ASLGIKTCGDLQYMTMAKLQKEFGPKTGQMLYRFCRGLDDRPVRTEKERKSVSAEINYGI 719 ASLGIKTCGDLQYMTMAKLQKEFGPKTGQMLYRFCRGLDDRPVRTEKERKSVSAEINYGI Sbjct: 661 ASLGIKTCGDLQYMTMAKLQKEFGPKTGQMLYRFCRGLDDRPVRTEKERKSVSAEINYGI 720 Query: 720 RFTQPKEAEAFLLSLSEEIQRRLEATGMKGKRLTLKIMVRKPGAPVETAKFGGHGICDNI 779 RFTQPKEAEAFLLSLSEEIQRRLEATGMKGKRLTLKIMVRKPGAPVETAKFGGHGICDNI Sbjct: 721 RFTQPKEAEAFLLSLSEEIQRRLEATGMKGKRLTLKIMVRKPGAPVETAKFGGHGICDNI 780 Query: 780 ARTVTLDQATDNAKIIGKAMLNMFHTMKLNISDMRGVGIHVNQLVPTNLNPSTCPSRPSV 839 ARTVTLDQATDNAKIIGKAMLNMFHTMKLNISDMRGVGIHVNQLVPTNLNPSTCPSRPSV Sbjct: 781 ARTVTLDQATDNAKIIGKAMLNMFHTMKLNISDMRGVGIHVNQLVPTNLNPSTCPSRPSV 840 Query: 840 QSSHFPSGSYSVRDVFQVQKAKKSTEEEHKEVFRAAVDLEISSASRTCTFLPPFPAHLPT 899 QSSHFPSGSYSVRDVFQVQKAKKSTEEEHKEVFRAAVDLEISSASRTCTFLPPFPAHLPT Sbjct: 841 QSSHFPSGSYSVRDVFQVQKAKKSTEEEHKEVFRAAVDLEISSASRTCTFLPPFPAHLPT 900 Query: 900 SPDTNKAESSGKWNGLHTPVSVQSRLNLSIEVPSPSQLDQSVLEALPPDLREQVEQVCAV 959 SPDTNKAESSGKWNGLHTPVSVQSRLNLSIEVPSPSQLDQSVLEALPPDLREQVEQVCAV Sbjct: 901 SPDTNKAESSGKWNGLHTPVSVQSRLNLSIEVPSPSQLDQSVLEALPPDLREQVEQVCAV 960 Query: 960 QQAESHGDKKKEPVNGCNTGILPQPVGTVLLQIPEPQESNSDAGINLIALPAFSQVDPEV 1019 QQAESHGDKKKEPVNGCNTGILPQPVGTVLLQIPEPQESNSDAGINLIALPAFSQVDPEV Sbjct: 961 QQAESHGDKKKEPVNGCNTGILPQPVGTVLLQIPEPQESNSDAGINLIALPAFSQVDPEV 1020 Query: 1020 FAALPAELQRELKAAYDQRQRQGENSTHQQSASASVPKNPLLHLKAAVKEKKRNKKKKTI 1079 FAALPAELQRELKAAYDQRQRQGENSTHQQSASASVPKNPLLHLKAAVKEKKRNKKKKTI Sbjct: 1021 FAALPAELQRELKAAYDQRQRQGENSTHQQSASASVPKNPLLHLKAAVKEKKRNKKKKTI 1080 Query: 1080 GSPKRIQSPLNNKLLNSPAKTLPGACGSPQKLIDGFLKHEGPPAEKPLEELSASTSGVPG 1139 GSPKRIQSPLNNKLLNSPAKTLPGACGSPQKLIDGFLKHEGPPAEKPLEELSASTSGVPG Sbjct: 1081 GSPKRIQSPLNNKLLNSPAKTLPGACGSPQKLIDGFLKHEGPPAEKPLEELSASTSGVPG 1140 Query: 1140 LSSLQSDPAGCVRPPAPNLAGAVEFNDVKTLLREWITTISDPMEEDILQVVKYCTDLIEE 1199 LSSLQSDPAGCVRPPAPNLAGAVEFNDVKTLLREWITTISDPMEEDILQVVKYCTDLIEE Sbjct: 1141 LSSLQSDPAGCVRPPAPNLAGAVEFNDVKTLLREWITTISDPMEEDILQVVKYCTDLIEE 1200 Query: 1200 KDLEKLDLVIKYMKRLMQQSVESVWNMAFDFILDNVQVVLQQTYGSTLKVT 1250 KDLEKLDLVIKYMKRLMQQSVESVWNMAFDFILDNVQVVLQQTYGSTLKVT Sbjct: 1201 KDLEKLDLVIKYMKRLMQQSVESVWNMAFDFILDNVQVVLQQTYGSTLKVT 1251 >gi|154350220 DNA polymerase iota [Homo sapiens] Length = 740 Score = 98.6 bits (244), Expect = 3e-20 Identities = 97/388 (25%), Positives = 158/388 (40%), Gaps = 94/388 (24%) Query: 409 VLNSPRHQS-CIMHVDMDCFFVSVGIRNRPDLKGKPVAVTSNRGTGRAPLRPGANPQLEW 467 VL +P S I+HVD+DCF+ V + + P+LK KP+ V Sbjct: 44 VLPTPNASSRVIVHVDLDCFYAQVEMISNPELKDKPLGV--------------------- 82 Query: 468 QYYQNKILKGKADIPDSSLWENPDSAQANGIDSVLSRAEIASCSYEARQLGIKNGMFFGH 527 Q K L + +C+YEAR+LG+K M Sbjct: 83 ---QQKYL-------------------------------VVTCNYEARKLGVKKLMNVRD 108 Query: 528 AKQLCPNLQAVP-YDFHAYKEVAQTLYETLASYTHNIEAVSCDEALVDITEILAET--KL 584 AK+ CP L V D Y+E++ + E L ++ +E + DE VD+TE++ + +L Sbjct: 109 AKEKCPQLVLVNGEDLTRYREMSYKVTELLEEFSPVVERLGFDENFVDLTEMVEKRLQQL 168 Query: 585 TPDEF-------------------------------ANAVRMEIKDQTKCAASVGIGSNI 613 DE A +R + +Q G+ SN Sbjct: 169 QSDELSAVTVSGHVYNNQSINLLDVLHIRLLVGSQIAAEMREAMYNQLGLTGCAGVASNK 228 Query: 614 LLARMATRKAKPDGQYHLKPEEVDDFIRG-QLVTNLPGVGHSMESKLASLGIKTCGDLQY 672 LLA++ + KP+ Q L PE I + +PG+G+ L +LGI + DLQ Sbjct: 229 LLAKLVSGVFKPNQQTVLLPESCQHLIHSLNHIKEIPGIGYKTAKCLEALGINSVRDLQT 288 Query: 673 MTMAKLQKEFGPKTGQMLYRFCRGLDDRPVRTEKERKSVSAEINYGIRFTQPKEAEAFLL 732 + L+KE G Q + + G D+ PV +S S E ++ + + EA+ + Sbjct: 289 FSPKILEKELGISVAQRIQKLSFGEDNSPVILSGPPQSFSEEDSFK-KCSSEVEAKNKIE 347 Query: 733 SLSEEIQRRLEATGMKGKRLTLKIMVRK 760 L + R+ G K T+++++R+ Sbjct: 348 ELLASLLNRVCQDGRKPH--TVRLIIRR 373 >gi|7705344 DNA-directed DNA polymerase kappa [Homo sapiens] Length = 870 Score = 95.9 bits (237), Expect = 2e-19 Identities = 101/394 (25%), Positives = 170/394 (43%), Gaps = 46/394 (11%) Query: 396 RSALVVTDTGDMSVLNSPRHQSCIMHVDMDCFFVSVGIRNRPDLKGKPVAV-------TS 448 R A + D M + S + I+H+DMD F+ +V +R+ P+LK KP+AV TS Sbjct: 80 RKAQLQVDRFAMELEQSRNLSNTIVHIDMDAFYAAVEMRDNPELKDKPIAVGSMSMLSTS 139 Query: 449 NRGTGRAPLR---PG-----ANPQL--------EWQYYQNKILKGKADIPDSSLWENPDS 492 N R +R PG PQL +++ ++ + AD + + + D Sbjct: 140 NYHARRFGVRAAMPGFIAKRLCPQLIIVPPNFDKYRAVSKEVKEILADYDPNFMAMSLDE 199 Query: 493 AQANGIDSVLSRAEIASCSYEARQLGIKNGMFFGHAKQLCPNLQAVPYDFHAYKEVAQTL 552 A N + R + R+ IK G + P + H + ++ L Sbjct: 200 AYLNITKHLEERQNWPE---DKRRYFIKMGSSVENDN---PGKEVNKLSEHE-RSISPLL 252 Query: 553 YETLAS--------YTHNIEAVSCDEALVDITEILAETKLTPDEFANAVRMEIKDQTKCA 604 +E S + N E + + L + ++ T + E +R I+ +T Sbjct: 253 FEESPSDVQPPGDPFQVNFEEQNNPQILQN--SVVFGT--SAQEVVKEIRFRIEQKTTLT 308 Query: 605 ASVGIGSNILLARMATRKAKPDGQYHLKP--EEVDDFIRGQLVTNLPGVGHSMESKLASL 662 AS GI N +LA++ + K KP+GQY + P + V DFI+ + + G+G E L +L Sbjct: 309 ASAGIAPNTMLAKVCSDKNKPNGQYQILPNRQAVMDFIKDLPIRKVSGIGKVTEKMLKAL 368 Query: 663 GIKTCGDLQYMTMAKLQKEFGPKTGQMLYRFCRGLDDRPVRTEKERKSVSAEINYGIRFT 722 GI TC +L Y A L F + GL + + ERKS+S E + Sbjct: 369 GIITCTEL-YQQRALLSLLFSETSWHYFLHISLGLGSTHLTRDGERKSMSVERTFS-EIN 426 Query: 723 QPKEAEAFLLSLSEEIQRRLEATGMKGKRLTLKI 756 + +E + L E+ + L+ +KG+ +T+K+ Sbjct: 427 KAEEQYSLCQELCSELAQDLQKERLKGRTVTIKL 460 >gi|5729982 DNA-directed DNA polymerase eta [Homo sapiens] Length = 713 Score = 69.3 bits (168), Expect = 2e-11 Identities = 45/169 (26%), Positives = 81/169 (47%), Gaps = 3/169 (1%) Query: 593 VRMEIKDQTKCAASVGIGSNILLARMATRKAKPDGQYHLKPEEVDDFIRGQLVTNLPGVG 652 +R I+ +T S GI N +LA++A KP+ Q + V + + +G Sbjct: 200 MRAAIERETGFQCSAGISHNKVLAKLACGLNKPNRQTLVSHGSVPQLFSQMPIRKIRSLG 259 Query: 653 HSM-ESKLASLGIKTCGDLQYMTMAKLQKEFGPKTGQMLYRFCRGLDDRPVRTEKERKSV 711 + S + LGI+ G+L T ++LQ FG K G LY CRG++ PV+ + K++ Sbjct: 260 GKLGASVIEILGIEYMGELTQFTESQLQSHFGEKNGSWLYAMCRGIEHDPVKPRQLPKTI 319 Query: 712 SAEINY--GIRFTQPKEAEAFLLSLSEEIQRRLEATGMKGKRLTLKIMV 758 N+ ++ + +LL L++E++ RL R+ +++V Sbjct: 320 GCSKNFPGKTALATREQVQWWLLQLAQELEERLTKDRNDNDRVATQLVV 368 Score = 51.2 bits (121), Expect = 6e-06 Identities = 47/167 (28%), Positives = 62/167 (37%), Gaps = 58/167 (34%) Query: 422 VDMDCFFVSVGIRNRPDLKGKPVAVTSNRGTGRAPLRPGANPQLEWQYYQNKILKGKADI 481 VDMDCFFV V R P L+ KP AV Q K KG Sbjct: 12 VDMDCFFVQVEQRQNPHLRNKPCAVV-----------------------QYKSWKGGG-- 46 Query: 482 PDSSLWENPDSAQANGIDSVLSRAEIASCSYEARQLGIKNGMFFGHAKQLCPNLQAVPY- 540 I + SYEAR G+ M+ AK+LCP+L Sbjct: 47 -------------------------IIAVSYEARAFGVTRSMWADDAKKLCPDLLLAQVR 81 Query: 541 ------DFHAYKEVAQTLYETLASYTHNIEAVSCDEALVDITEILAE 581 + Y+E + + E ++ + IE S DEA VD+T + E Sbjct: 82 ESRGKANLTKYREASVEVMEIMSRFA-VIERASIDEAYVDLTSAVQE 127 >gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens] Length = 4374 Score = 40.4 bits (93), Expect = 0.011 Identities = 36/140 (25%), Positives = 59/140 (42%), Gaps = 32/140 (22%) Query: 934 PSQLDQSVLEALPPDLREQVEQVCAVQQAESHGDKKKEPVNGCNTGILPQPVGTVLLQIP 993 P +D S L ALP D+R +V Q GI P P T Sbjct: 2965 PEGVDPSFLAALPDDIRREVLQN--------------------QLGIRP-PTRTA----- 2998 Query: 994 EPQESNSDAGINLIALPAFSQVDPEVFAALPAELQRELKAAYDQRQRQGENSTHQQSASA 1053 S + + ++ P ++V PE AALP +Q E+ A Q++ E + Q+AS+ Sbjct: 2999 ---PSTNSSAPAVVGNPGVTEVSPEFLAALPPAIQEEVLAQQRAEQQRRELA---QNASS 3052 Query: 1054 SVPKNPLLHLKAAVKEKKRN 1073 P +P+ ++ + +R+ Sbjct: 3053 DTPMDPVTFIQTLPSDLRRS 3072 Score = 31.6 bits (70), Expect = 5.0 Identities = 41/177 (23%), Positives = 67/177 (37%), Gaps = 32/177 (18%) Query: 894 PAHLPTSPDTNKAESSGKWNGLHTPVSVQSRLNLSIEV----PSPSQLDQSVLEALPPDL 949 P+ L PD + E G+ P N S P +++ L ALPP + Sbjct: 2970 PSFLAALPDDIRREVLQNQLGIRPPTRTAPSTNSSAPAVVGNPGVTEVSPEFLAALPPAI 3029 Query: 950 REQVEQVCAVQQAESHGDKKKEPVNGCNTGILPQPVGTVLLQIPEPQESNSDAGINLIAL 1009 + E+V A Q+AE +++E ++ PV T + +P + Sbjct: 3030 Q---EEVLAQQRAE---QQRRELAQNASSDTPMDPV-TFIQTLPSD-----------LRR 3071 Query: 1010 PAFSQVDPEVFAALPAELQRE---LKAAYDQRQRQ-------GENSTHQQSASASVP 1056 ++ V A +P ++ E L+ + RQRQ G +ST SA P Sbjct: 3072 SVLEDMEDSVLAVMPPDIAAEAQALRREQEARQRQLMHERLFGHSSTSALSAILRSP 3128 >gi|195972857 Rho/Rac guanine nucleotide exchange factor 18 isoform b [Homo sapiens] Length = 1173 Score = 38.1 bits (87), Expect = 0.053 Identities = 55/224 (24%), Positives = 81/224 (36%), Gaps = 40/224 (17%) Query: 944 ALPPDLREQVEQVCAVQQAESHGDK-KKEPVNGCNTGILPQPVGTVLLQIPE-------P 995 ALPPD A Q SH E + G +LP VG + PE P Sbjct: 964 ALPPD-------TLAEAQPPSHPPSFNGEGLEGPRVSMLPSGVGPEYAERPEVARRDSAP 1016 Query: 996 QESN---SDAGINLIALPAFSQVDPEVFAALPAELQRELKAAYDQRQRQGENSTHQQSAS 1052 E+ SD I L++ Q V +P +L K D+ + + + SAS Sbjct: 1017 TENRLAKSDVPIQLLSATNQFQRQAAVQQQIPTKLAASTKGGKDKGGKSRGSQRWESSAS 1076 Query: 1053 ASVPKNPLLHLKAAVKEKKRNKKKKTIGSPKRIQSPLNNKLLNSPAKTLPGACGSPQKLI 1112 + + LL+ K K++ ++ ++++ SP+ LPG Sbjct: 1077 FDLKQQLLLN-KLMGKDESTSRNRRSL-------SPI-----------LPGRHSPAPPPD 1117 Query: 1113 DGFLKHEGPPAEKPLEELSASTSGVPGLSSLQSDPAGCVRPPAP 1156 GF PPA+ P E S G + L PA P P Sbjct: 1118 PGFPAPSPPPADSPSEGFSLKAGGT---ALLPGPPAPSPLPATP 1158 >gi|41327769 Rho/Rac guanine nucleotide exchange factor 18 isoform a [Homo sapiens] Length = 1015 Score = 38.1 bits (87), Expect = 0.053 Identities = 55/224 (24%), Positives = 81/224 (36%), Gaps = 40/224 (17%) Query: 944 ALPPDLREQVEQVCAVQQAESHGDK-KKEPVNGCNTGILPQPVGTVLLQIPE-------P 995 ALPPD A Q SH E + G +LP VG + PE P Sbjct: 806 ALPPD-------TLAEAQPPSHPPSFNGEGLEGPRVSMLPSGVGPEYAERPEVARRDSAP 858 Query: 996 QESN---SDAGINLIALPAFSQVDPEVFAALPAELQRELKAAYDQRQRQGENSTHQQSAS 1052 E+ SD I L++ Q V +P +L K D+ + + + SAS Sbjct: 859 TENRLAKSDVPIQLLSATNQFQRQAAVQQQIPTKLAASTKGGKDKGGKSRGSQRWESSAS 918 Query: 1053 ASVPKNPLLHLKAAVKEKKRNKKKKTIGSPKRIQSPLNNKLLNSPAKTLPGACGSPQKLI 1112 + + LL+ K K++ ++ ++++ SP+ LPG Sbjct: 919 FDLKQQLLLN-KLMGKDESTSRNRRSL-------SPI-----------LPGRHSPAPPPD 959 Query: 1113 DGFLKHEGPPAEKPLEELSASTSGVPGLSSLQSDPAGCVRPPAP 1156 GF PPA+ P E S G + L PA P P Sbjct: 960 PGFPAPSPPPADSPSEGFSLKAGGT---ALLPGPPAPSPLPATP 1000 >gi|236462242 potassium voltage-gated channel, KQT-like subfamily, member 5 isoform 5 [Homo sapiens] Length = 822 Score = 37.7 bits (86), Expect = 0.069 Identities = 52/229 (22%), Positives = 89/229 (38%), Gaps = 25/229 (10%) Query: 813 MRGVGIHVNQLVPTNLNPSTCPSRPSVQSSHFPSGSYSVRD-VFQVQKAKKSTEEEHK-- 869 ++ + V+Q++ S SR + + H + S+ V +V+K +S E + Sbjct: 454 IKSLQTRVDQILGKGQITSDKKSREKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCL 513 Query: 870 -EVFRAAVDLEISSASRTCTF-LPPFPAHLPT---SPDTNKAESSGKWNGLHTPVSVQSR 924 ++++ + +SA +F +PPF + SP +K S N S + Sbjct: 514 LDIYQQVLRKGSASALALASFQIPPFECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSAN 573 Query: 925 LNLSIE-VPSPSQLDQSVLEALPPDLREQVEQVCAVQQAESHGDKKKEPVNGCNTGILPQ 983 ++ ++ + +P++ AL P + Q QV Q S N NT P+ Sbjct: 574 ISRGLQFILTPNEFSAQTFYALSPTMHSQATQVPISQSDGSAVAATNTIANQINTA--PK 631 Query: 984 PVGTVLLQIPEPQESNSDAGINLIALPAFSQVD-PEVFAALPAELQREL 1031 P LQIP P LPA + PE PA LQ + Sbjct: 632 PAAPTTLQIPPP-------------LPAIKHLPRPETLHPNPAGLQESI 667 >gi|236462079 potassium voltage-gated channel, KQT-like subfamily, member 5 isoform 4 [Homo sapiens] Length = 951 Score = 37.7 bits (86), Expect = 0.069 Identities = 52/229 (22%), Positives = 89/229 (38%), Gaps = 25/229 (10%) Query: 813 MRGVGIHVNQLVPTNLNPSTCPSRPSVQSSHFPSGSYSVRD-VFQVQKAKKSTEEEHK-- 869 ++ + V+Q++ S SR + + H + S+ V +V+K +S E + Sbjct: 583 IKSLQTRVDQILGKGQITSDKKSREKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCL 642 Query: 870 -EVFRAAVDLEISSASRTCTF-LPPFPAHLPT---SPDTNKAESSGKWNGLHTPVSVQSR 924 ++++ + +SA +F +PPF + SP +K S N S + Sbjct: 643 LDIYQQVLRKGSASALALASFQIPPFECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSAN 702 Query: 925 LNLSIE-VPSPSQLDQSVLEALPPDLREQVEQVCAVQQAESHGDKKKEPVNGCNTGILPQ 983 ++ ++ + +P++ AL P + Q QV Q S N NT P+ Sbjct: 703 ISRGLQFILTPNEFSAQTFYALSPTMHSQATQVPISQSDGSAVAATNTIANQINTA--PK 760 Query: 984 PVGTVLLQIPEPQESNSDAGINLIALPAFSQVD-PEVFAALPAELQREL 1031 P LQIP P LPA + PE PA LQ + Sbjct: 761 PAAPTTLQIPPP-------------LPAIKHLPRPETLHPNPAGLQESI 796 >gi|236461942 potassium voltage-gated channel, KQT-like subfamily, member 5 isoform 3 [Homo sapiens] Length = 942 Score = 37.7 bits (86), Expect = 0.069 Identities = 52/229 (22%), Positives = 89/229 (38%), Gaps = 25/229 (10%) Query: 813 MRGVGIHVNQLVPTNLNPSTCPSRPSVQSSHFPSGSYSVRD-VFQVQKAKKSTEEEHK-- 869 ++ + V+Q++ S SR + + H + S+ V +V+K +S E + Sbjct: 574 IKSLQTRVDQILGKGQITSDKKSREKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCL 633 Query: 870 -EVFRAAVDLEISSASRTCTF-LPPFPAHLPT---SPDTNKAESSGKWNGLHTPVSVQSR 924 ++++ + +SA +F +PPF + SP +K S N S + Sbjct: 634 LDIYQQVLRKGSASALALASFQIPPFECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSAN 693 Query: 925 LNLSIE-VPSPSQLDQSVLEALPPDLREQVEQVCAVQQAESHGDKKKEPVNGCNTGILPQ 983 ++ ++ + +P++ AL P + Q QV Q S N NT P+ Sbjct: 694 ISRGLQFILTPNEFSAQTFYALSPTMHSQATQVPISQSDGSAVAATNTIANQINTA--PK 751 Query: 984 PVGTVLLQIPEPQESNSDAGINLIALPAFSQVD-PEVFAALPAELQREL 1031 P LQIP P LPA + PE PA LQ + Sbjct: 752 PAAPTTLQIPPP-------------LPAIKHLPRPETLHPNPAGLQESI 787 >gi|236461719 potassium voltage-gated channel, KQT-like subfamily, member 5 isoform 2 [Homo sapiens] Length = 923 Score = 37.7 bits (86), Expect = 0.069 Identities = 52/229 (22%), Positives = 89/229 (38%), Gaps = 25/229 (10%) Query: 813 MRGVGIHVNQLVPTNLNPSTCPSRPSVQSSHFPSGSYSVRD-VFQVQKAKKSTEEEHK-- 869 ++ + V+Q++ S SR + + H + S+ V +V+K +S E + Sbjct: 555 IKSLQTRVDQILGKGQITSDKKSREKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCL 614 Query: 870 -EVFRAAVDLEISSASRTCTF-LPPFPAHLPT---SPDTNKAESSGKWNGLHTPVSVQSR 924 ++++ + +SA +F +PPF + SP +K S N S + Sbjct: 615 LDIYQQVLRKGSASALALASFQIPPFECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSAN 674 Query: 925 LNLSIE-VPSPSQLDQSVLEALPPDLREQVEQVCAVQQAESHGDKKKEPVNGCNTGILPQ 983 ++ ++ + +P++ AL P + Q QV Q S N NT P+ Sbjct: 675 ISRGLQFILTPNEFSAQTFYALSPTMHSQATQVPISQSDGSAVAATNTIANQINTA--PK 732 Query: 984 PVGTVLLQIPEPQESNSDAGINLIALPAFSQVD-PEVFAALPAELQREL 1031 P LQIP P LPA + PE PA LQ + Sbjct: 733 PAAPTTLQIPPP-------------LPAIKHLPRPETLHPNPAGLQESI 768 >gi|28373065 potassium voltage-gated channel, KQT-like subfamily, member 5 isoform 1 [Homo sapiens] Length = 932 Score = 37.7 bits (86), Expect = 0.069 Identities = 52/229 (22%), Positives = 89/229 (38%), Gaps = 25/229 (10%) Query: 813 MRGVGIHVNQLVPTNLNPSTCPSRPSVQSSHFPSGSYSVRD-VFQVQKAKKSTEEEHK-- 869 ++ + V+Q++ S SR + + H + S+ V +V+K +S E + Sbjct: 564 IKSLQTRVDQILGKGQITSDKKSREKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCL 623 Query: 870 -EVFRAAVDLEISSASRTCTF-LPPFPAHLPT---SPDTNKAESSGKWNGLHTPVSVQSR 924 ++++ + +SA +F +PPF + SP +K S N S + Sbjct: 624 LDIYQQVLRKGSASALALASFQIPPFECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSAN 683 Query: 925 LNLSIE-VPSPSQLDQSVLEALPPDLREQVEQVCAVQQAESHGDKKKEPVNGCNTGILPQ 983 ++ ++ + +P++ AL P + Q QV Q S N NT P+ Sbjct: 684 ISRGLQFILTPNEFSAQTFYALSPTMHSQATQVPISQSDGSAVAATNTIANQINTA--PK 741 Query: 984 PVGTVLLQIPEPQESNSDAGINLIALPAFSQVD-PEVFAALPAELQREL 1031 P LQIP P LPA + PE PA LQ + Sbjct: 742 PAAPTTLQIPPP-------------LPAIKHLPRPETLHPNPAGLQESI 777 >gi|194440660 topoisomerase (DNA) II binding protein 1 [Homo sapiens] Length = 1522 Score = 37.7 bits (86), Expect = 0.069 Identities = 23/76 (30%), Positives = 36/76 (47%), Gaps = 2/76 (2%) Query: 48 IFSGVAIYVNGYTDPSAEELRKLMMLHGGQYHVYYSRSKTTHIIATNLPNAKIKELKGEK 107 IF G I V G +E+++L + HGGQY ++ TH+I K + K Sbjct: 199 IFLGCIICVTGLCGLDRKEVQQLTVKHGGQYMGQLKMNECTHLIVQEPKGQKYECAKRWN 258 Query: 108 V--IRPEWIVESIKAG 121 V + +W +SI+ G Sbjct: 259 VHCVTTQWFFDSIEKG 274 Score = 34.3 bits (77), Expect = 0.76 Identities = 25/104 (24%), Positives = 48/104 (46%), Gaps = 8/104 (7%) Query: 48 IFSGVAIYVNGYTDPSAEELRKLMMLHGGQYHVYYSRSKTTHIIATNLPNAKIKELKGEK 107 + G IY+ G++ ++LR+L+ GG TH+I + + ++K+ + Sbjct: 358 LLDGCRIYLCGFSGRKLDKLRRLIN-SGGGVRFNQLNEDVTHVIVGDYDD-ELKQFWNKS 415 Query: 108 VIRP-----EWIVESIKAGRLLSYIPYQLYTKQSSVQKGLSFNP 146 RP +W++E G +LS PY ++ V+ +S P Sbjct: 416 AHRPHVVGAKWLLECFSKGYMLSEEPY-IHANYQPVEIPVSHKP 458 >gi|150170670 piccolo isoform 2 [Homo sapiens] Length = 4935 Score = 35.4 bits (80), Expect = 0.34 Identities = 49/185 (26%), Positives = 76/185 (41%), Gaps = 29/185 (15%) Query: 957 CAVQQAESH--GDKKKEPVNGCNTGILPQPVGTVLLQIPEPQESNSDAGINLIALPAFSQ 1014 C Q+A S GD +K P P P G +P P ES+S + + Sbjct: 1109 CQTQRAISGQLGDIRKMP---------PAPSGPKASPMPVPTESSSQKTAVPPQVKLVKK 1159 Query: 1015 VDPEVFAALPAELQRELKAAYDQR---------QRQGENSTHQQSASASVPKNPLLHLKA 1065 + EV + ++K Q+Q E+ + ASA K PL K Sbjct: 1160 QEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKK 1219 Query: 1066 AV--KEKKRNKKKKTIGSPKRIQSPLNNKLLNSPAKTLPGACGSPQKLIDGFLKHEGPPA 1123 + +EK R+++KK + K+ +P + KLL AKT +P++ LK + A Sbjct: 1220 LIPEEEKIRSEEKKPLLEEKK-PTPEDKKLL-PEAKT-----SAPEEQKHDLLKSQVQIA 1272 Query: 1124 EKPLE 1128 E+ LE Sbjct: 1273 EEKLE 1277 >gi|150378539 piccolo isoform 1 [Homo sapiens] Length = 5142 Score = 35.4 bits (80), Expect = 0.34 Identities = 49/185 (26%), Positives = 76/185 (41%), Gaps = 29/185 (15%) Query: 957 CAVQQAESH--GDKKKEPVNGCNTGILPQPVGTVLLQIPEPQESNSDAGINLIALPAFSQ 1014 C Q+A S GD +K P P P G +P P ES+S + + Sbjct: 1109 CQTQRAISGQLGDIRKMP---------PAPSGPKASPMPVPTESSSQKTAVPPQVKLVKK 1159 Query: 1015 VDPEVFAALPAELQRELKAAYDQR---------QRQGENSTHQQSASASVPKNPLLHLKA 1065 + EV + ++K Q+Q E+ + ASA K PL K Sbjct: 1160 QEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKK 1219 Query: 1066 AV--KEKKRNKKKKTIGSPKRIQSPLNNKLLNSPAKTLPGACGSPQKLIDGFLKHEGPPA 1123 + +EK R+++KK + K+ +P + KLL AKT +P++ LK + A Sbjct: 1220 LIPEEEKIRSEEKKPLLEEKK-PTPEDKKLL-PEAKT-----SAPEEQKHDLLKSQVQIA 1272 Query: 1124 EKPLE 1128 E+ LE Sbjct: 1273 EEKLE 1277 >gi|110611228 utrophin [Homo sapiens] Length = 3433 Score = 35.0 bits (79), Expect = 0.45 Identities = 45/207 (21%), Positives = 78/207 (37%), Gaps = 29/207 (14%) Query: 151 EDPLPGPSNIAKQLNNRVNHIVKKIETENEVKVNGMNSWNEEDENNDFSFVDLEQTSPGR 210 E P+ P + A+ I+K +E E ++ + + EE++ N V+ EQ Sbjct: 3239 ESPVSQPQSPAQ--------ILKSVEREERGELERIIADLEEEQRN--LQVEYEQLKDQH 3288 Query: 211 KQNGIPHPRGSTAIFNGHTPSSNGALKTQDCLVPMVNSVASRLSPAFSQEEDKAEKSSTD 270 + G+P +I + H S + L + ++ RL ED ++ + Sbjct: 3289 LRRGLPVGSPPESIISPHHTSEDSELIAE---AKLLRQHKGRLEARMQILEDHNKQLESQ 3345 Query: 271 FRDCTLQQLQQSTRNTDALRN-------PHRTNSFSLSPLHSNTKINGAHHSTVQGPSST 323 L+QL + + + H S+SL P S + + A + P Sbjct: 3346 LH--RLRQLLEQPESDSRINGVSPWASPQHSALSYSLDPDASGPQFHQAAGEDLLAPPHD 3403 Query: 324 KSTSSV-------STFSKAAPSVPSKP 343 ST STF P+VPS+P Sbjct: 3404 TSTDLTEVMEQIHSTFPSCCPNVPSRP 3430 >gi|7657218 bromodomain-containing protein 4 isoform short [Homo sapiens] Length = 722 Score = 34.7 bits (78), Expect = 0.59 Identities = 41/166 (24%), Positives = 73/166 (43%), Gaps = 23/166 (13%) Query: 967 DKKKEPVNGCNTGILPQPVGTVLLQIPEPQESNSDAGINLIALPAFSQVDPEVFAALPAE 1026 D+ +EPV ++ +P P T ++ P +S+SD+ + + S+ E A AE Sbjct: 459 DEPEEPVVAVSSPAVPPP--TKVVAPPSSSDSSSDSSSDSDSSTDDSE---EERAQRLAE 513 Query: 1027 LQRELKAAYDQ---RQRQGENSTHQQSASASVPKNPLLHLKAAVKEKKRNKKKKTIGSPK 1083 LQ +LKA ++Q + +N ++ K K V+E K++K K+ PK Sbjct: 514 LQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEP--PPK 571 Query: 1084 RIQSPLNNKLLNSPAKTLPGACGSPQKLIDGFLKHEGPPAEKPLEE 1129 + + NN ++ +K P +K + PP + EE Sbjct: 572 KTKK--NNSSNSNVSKKEPAP-----------MKSKPPPTYESEEE 604 >gi|19718731 bromodomain-containing protein 4 isoform long [Homo sapiens] Length = 1362 Score = 34.7 bits (78), Expect = 0.59 Identities = 41/166 (24%), Positives = 73/166 (43%), Gaps = 23/166 (13%) Query: 967 DKKKEPVNGCNTGILPQPVGTVLLQIPEPQESNSDAGINLIALPAFSQVDPEVFAALPAE 1026 D+ +EPV ++ +P P T ++ P +S+SD+ + + S+ E A AE Sbjct: 459 DEPEEPVVAVSSPAVPPP--TKVVAPPSSSDSSSDSSSDSDSSTDDSE---EERAQRLAE 513 Query: 1027 LQRELKAAYDQ---RQRQGENSTHQQSASASVPKNPLLHLKAAVKEKKRNKKKKTIGSPK 1083 LQ +LKA ++Q + +N ++ K K V+E K++K K+ PK Sbjct: 514 LQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEP--PPK 571 Query: 1084 RIQSPLNNKLLNSPAKTLPGACGSPQKLIDGFLKHEGPPAEKPLEE 1129 + + NN ++ +K P +K + PP + EE Sbjct: 572 KTKK--NNSSNSNVSKKEPAP-----------MKSKPPPTYESEEE 604 >gi|239757877 PREDICTED: FERM and PDZ domain containing 3 [Homo sapiens] Length = 1662 Score = 34.3 bits (77), Expect = 0.76 Identities = 33/118 (27%), Positives = 49/118 (41%), Gaps = 15/118 (12%) Query: 284 RNTDALRNPHRTNSFSLSPLHS-NTKINGAHHSTVQGPSSTKSTSSV----STFSKAAPS 338 R LR+ + S P T +NGAH ST +GP+ KS+ + FS P+ Sbjct: 1053 RGQSPLRSQAASRQVSTMPSRKLETTLNGAH-STSEGPAKPKSSRGPFRLRNLFSATFPT 1111 Query: 339 VPSKPSDCNFISNFYSHSRLHHISMWKCELTEFVNTLQRQSNGIFPGREKLKKMKTGR 396 K +D ++L + ++ E E L+ S G PG E L+ GR Sbjct: 1112 RQKKETD-------ERQAQLQKVKQYELEFLE--ELLKPPSQGELPGTEYLQPPAPGR 1160 >gi|89060961 PREDICTED: FERM and PDZ domain containing 3 [Homo sapiens] Length = 1810 Score = 34.3 bits (77), Expect = 0.76 Identities = 33/118 (27%), Positives = 49/118 (41%), Gaps = 15/118 (12%) Query: 284 RNTDALRNPHRTNSFSLSPLHS-NTKINGAHHSTVQGPSSTKSTSSV----STFSKAAPS 338 R LR+ + S P T +NGAH ST +GP+ KS+ + FS P+ Sbjct: 1201 RGQSPLRSQAASRQVSTMPSRKLETTLNGAH-STSEGPAKPKSSRGPFRLRNLFSATFPT 1259 Query: 339 VPSKPSDCNFISNFYSHSRLHHISMWKCELTEFVNTLQRQSNGIFPGREKLKKMKTGR 396 K +D ++L + ++ E E L+ S G PG E L+ GR Sbjct: 1260 RQKKETD-------ERQAQLQKVKQYELEFLE--ELLKPPSQGELPGTEYLQPPAPGR 1308 >gi|89059963 PREDICTED: FERM and PDZ domain containing 3 [Homo sapiens] Length = 1810 Score = 34.3 bits (77), Expect = 0.76 Identities = 33/118 (27%), Positives = 49/118 (41%), Gaps = 15/118 (12%) Query: 284 RNTDALRNPHRTNSFSLSPLHS-NTKINGAHHSTVQGPSSTKSTSSV----STFSKAAPS 338 R LR+ + S P T +NGAH ST +GP+ KS+ + FS P+ Sbjct: 1201 RGQSPLRSQAASRQVSTMPSRKLETTLNGAH-STSEGPAKPKSSRGPFRLRNLFSATFPT 1259 Query: 339 VPSKPSDCNFISNFYSHSRLHHISMWKCELTEFVNTLQRQSNGIFPGREKLKKMKTGR 396 K +D ++L + ++ E E L+ S G PG E L+ GR Sbjct: 1260 RQKKETD-------ERQAQLQKVKQYELEFLE--ELLKPPSQGELPGTEYLQPPAPGR 1308 >gi|83367077 mucin 16 [Homo sapiens] Length = 14507 Score = 33.9 bits (76), Expect = 1.00 Identities = 30/111 (27%), Positives = 47/111 (42%), Gaps = 6/111 (5%) Query: 232 SNGALKTQDCLVPMVNSVASRLSPAFSQEEDKAEKSSTDFRDCTLQQLQQSTRNTDALRN 291 S+ + Q P VNSVA SP +S+ + +L+ L + +A+ + Sbjct: 1991 SSEKVSVQTQSTPYVNSVAVSASPTHENSVSSGSSTSSPYSSASLESLDSTISRRNAITS 2050 Query: 292 PHRTNSFSLS----PLHSNTKINGAHHSTVQGPSSTKSTSSVSTFSKAAPS 338 + SL P S ++ + HS V PSST T+ FS A+ S Sbjct: 2051 WLWDLTTSLPTTTWPSTSLSEALSSGHSGVSNPSST--TTEFPLFSAASTS 2099 >gi|239754668 PREDICTED: mucin 12 [Homo sapiens] Length = 1952 Score = 33.9 bits (76), Expect = 1.00 Identities = 33/128 (25%), Positives = 48/128 (37%), Gaps = 16/128 (12%) Query: 248 SVASRLSPAFSQEEDKAEKSSTDFRDCTLQQLQQSTRNTDALRNPHRTNSFSL----SPL 303 S + LSP + +S+T S T R P T + L +P+ Sbjct: 266 STDTTLSPGTTTPSSLGPESTT---------FHSSPGYTKTTRLPDNTTTSGLLEASTPV 316 Query: 304 HSNTKINGAHHSTVQGPSSTKSTSSVSTFSKAAPSVPSKPSDCNFISNFYSHSRLHHISM 363 HS+T G+ H+T+ SST +TF S + P+ S F S +H S Sbjct: 317 HSST---GSPHTTLSPASSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSP 373 Query: 364 WKCELTEF 371 T F Sbjct: 374 SSTPTTHF 381 >gi|239749217 PREDICTED: similar to Mucin-12, partial [Homo sapiens] Length = 861 Score = 33.9 bits (76), Expect = 1.00 Identities = 33/128 (25%), Positives = 48/128 (37%), Gaps = 16/128 (12%) Query: 248 SVASRLSPAFSQEEDKAEKSSTDFRDCTLQQLQQSTRNTDALRNPHRTNSFSL----SPL 303 S + LSP + +S+T S T R P T + L +P+ Sbjct: 201 STDTTLSPGTTTPSSLGPESTT---------FHSSPGYTKTTRLPDNTTTSGLLEASTPV 251 Query: 304 HSNTKINGAHHSTVQGPSSTKSTSSVSTFSKAAPSVPSKPSDCNFISNFYSHSRLHHISM 363 HS+T G+ H+T+ SST +TF S + P+ S F S +H S Sbjct: 252 HSST---GSPHTTLSPSSSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSP 308 Query: 364 WKCELTEF 371 T F Sbjct: 309 SSTPTTHF 316 >gi|239743293 PREDICTED: mucin 12 [Homo sapiens] Length = 5478 Score = 33.9 bits (76), Expect = 1.00 Identities = 33/128 (25%), Positives = 48/128 (37%), Gaps = 16/128 (12%) Query: 248 SVASRLSPAFSQEEDKAEKSSTDFRDCTLQQLQQSTRNTDALRNPHRTNSFSL----SPL 303 S + LSP + +S+T S T R P T + L +P+ Sbjct: 345 STDTTLSPGTTTPSSLGPESTT---------FHSSPGYTKTTRLPDNTTTSGLLEASTPV 395 Query: 304 HSNTKINGAHHSTVQGPSSTKSTSSVSTFSKAAPSVPSKPSDCNFISNFYSHSRLHHISM 363 HS+T G+ H+T+ SST +TF S + P+ S F S +H S Sbjct: 396 HSST---GSPHTTLSPSSSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSP 452 Query: 364 WKCELTEF 371 T F Sbjct: 453 SSTPTTHF 460 >gi|239745855 PREDICTED: hypothetical protein XP_002343606 [Homo sapiens] Length = 870 Score = 33.5 bits (75), Expect = 1.3 Identities = 38/170 (22%), Positives = 62/170 (36%), Gaps = 14/170 (8%) Query: 898 PTSPDTNKAESSGKWNGLHTPVSVQSRLNLSIEVPSPSQ---LDQSVLEALPPDLREQV- 953 P P + E TP +++ P Q LD + PPD++ + Sbjct: 363 PVQPSESSREVESSLTQQETPGQPPEHHEVTVSPPGHHQTHHLDSPSVSVKPPDVQLTIA 422 Query: 954 -EQVCAVQQAESHGDKKKEPVNGCNTGILPQPV---GTVLLQIPEPQESNSDAGINLIAL 1009 E V + H + ++G + P + G LL ES+ +AG + Sbjct: 423 AEPSAEVGTSLVHQEATAR-LSGSGNDVEPPAIQHGGPPLLP-----ESSEEAGPLAVQQ 476 Query: 1010 PAFSQVDPEVFAALPAELQRELKAAYDQRQRQGENSTHQQSASASVPKNP 1059 Q + P+ Q+E A + Q +GE+S Q A A P+ P Sbjct: 477 ETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFP 526 >gi|151301154 mucin 6, gastric [Homo sapiens] Length = 2439 Score = 33.1 bits (74), Expect = 1.7 Identities = 29/127 (22%), Positives = 52/127 (40%), Gaps = 14/127 (11%) Query: 218 PRGSTAIFNGHTPSSNGALKTQDCLVPMVNSVASRLSPAFSQEEDKAEKSSTDFRDCTLQ 277 PR +TA+ TP + L P ++ P +Q +A S+ T Sbjct: 1272 PRPTTAV----TPQATSGLP------PTATLRSTATKPTVTQATTRATASTAS--PATTS 1319 Query: 278 QLQQSTRNTDALRNPHRTNSFSLSPLHSNTKINGAHHSTVQGPSSTKSTSSVSTFSKAAP 337 Q +TR T L P + + P +N ++ G + GP T ++++ T + P Sbjct: 1320 TAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTGPTTPQ--P 1377 Query: 338 SVPSKPS 344 P++P+ Sbjct: 1378 GQPTRPT 1384 Score = 32.3 bits (72), Expect = 2.9 Identities = 28/129 (21%), Positives = 57/129 (44%), Gaps = 10/129 (7%) Query: 230 PSSNGALKTQDCLVPMVNSVASRLSPAFSQEEDKAEKSSTDFRDCTLQQLQQSTRNTDAL 289 P ++ + + + ++S +P + + + S + T+ S+ ++ Sbjct: 2095 PQNSSSRPPSSPITTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQT 2154 Query: 290 RNPH--RTNSFSLSPLHSNTKINGAHHSTVQGPSSTKSTSSVSTFSKAAPSVPSKPSDCN 347 +P ++SF +P+HS T +G+H S S+ +T+SVS A+P PS P+ Sbjct: 2155 SSPSVGTSSSFVSAPVHSTTLSSGSHSSL----STHPTTASVS----ASPLFPSSPAAST 2206 Query: 348 FISNFYSHS 356 I H+ Sbjct: 2207 TIRATLPHT 2215 >gi|154091020 leucine-rich repeats and calponin homology (CH) domain containing 2 [Homo sapiens] Length = 765 Score = 32.7 bits (73), Expect = 2.2 Identities = 29/134 (21%), Positives = 55/134 (41%), Gaps = 11/134 (8%) Query: 164 LNNRVNHIVKKIETENEVKVNGMNSWNEEDENNDFSFVDLEQTSPGRKQNGIPHPRGSTA 223 L+++V+ ++ + N+ + G + +++D+ + FVD + G H + Sbjct: 371 LHSQVSESNREQTSRNDSHIIGSKTDSQKDQEV-YDFVDPNTEDVAVPEQGNAHIGSFVS 429 Query: 224 IFNGHTPSSNGALKTQDCLVPMVNSVASRLSPAFSQEEDKAEKSSTDFRDCTLQQLQQST 283 F G S + K ++ + + ++EED K TD R Q LQQ Sbjct: 430 FFKGKEKCSEKSRKNEE----LGDEKRLEKEQLLAEEEDDDLKEVTDLRKIAAQLLQQEQ 485 Query: 284 RN------TDALRN 291 +N T +RN Sbjct: 486 KNRILNHSTSVMRN 499 >gi|161016767 mucin 21 [Homo sapiens] Length = 566 Score = 32.7 bits (73), Expect = 2.2 Identities = 32/147 (21%), Positives = 63/147 (42%), Gaps = 4/147 (2%) Query: 195 NNDFSFVDLEQTSPGRKQNGIPHPRGSTAIFNGHTPSSNGALKTQDCLVPMVNSVASRLS 254 N++ S ++ ++ P STA + + +S+GA + +S AS + Sbjct: 107 NSESSTTSSGASTATNSESSTPSSGASTATNSDSSTTSSGASTATNSDSSTTSSEASTAT 166 Query: 255 PAFSQEEDKAEKSSTDFRDCTLQQLQQSTRNTDALRNPHRTNSFSLSPLHSNTKINGAHH 314 + S ++T+ T+ + N+++ ++ + S S T NGA Sbjct: 167 NSESSTTSSGASTATNSESSTVSSRASTATNSESSTTSSGASTATNS--ESRTTSNGAGT 224 Query: 315 STVQGPSSTKSTSSVSTFSKAAPSVPS 341 +T S+T S +S +T S++ S PS Sbjct: 225 ATNSESSTTSSGASTATNSES--STPS 249 Score = 32.0 bits (71), Expect = 3.8 Identities = 37/150 (24%), Positives = 62/150 (41%), Gaps = 11/150 (7%) Query: 195 NNDFSFVDLEQTSPGRKQNGIPHPRGSTAIFNGHTPSSNGALKTQDCLVPMVNSVASRLS 254 N++ S V ++ ++ P +TA + + +S+GA NS +S S Sbjct: 272 NSESSTVSSGISTVTNSESSTPSSGANTATNSESSTTSSGANTA-------TNSDSSTTS 324 Query: 255 PAFSQEEDKAEKSSTDFRDCTLQQLQQSTRNTDALRNPHRTNSFSLSPLHSNTKINGAHH 314 S + +E S+T T + ST ++ A TNS S + + + Sbjct: 325 SGASTATN-SESSTTSSGASTATNSESSTTSSGAST---ATNSGSSTTSSGTSTATNSES 380 Query: 315 STVQGPSSTKSTSSVSTFSKAAPSVPSKPS 344 STV +ST +TS ST S A + + S Sbjct: 381 STVSSGASTATTSESSTTSSGASTATNSES 410 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.314 0.130 0.377 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 49,877,088 Number of Sequences: 37866 Number of extensions: 2401448 Number of successful extensions: 6400 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 10 Number of HSP's successfully gapped in prelim test: 53 Number of HSP's that attempted gapping in prelim test: 6277 Number of HSP's gapped (non-prelim): 180 length of query: 1250 length of database: 18,247,518 effective HSP length: 114 effective length of query: 1136 effective length of database: 13,930,794 effective search space: 15825381984 effective search space used: 15825381984 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (22.0 bits) S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.