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Search of human proteins with 84043967
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|84043967 REV1-like isoform 2 [Homo sapiens]
(1250 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|84043967 REV1-like isoform 2 [Homo sapiens] 2507 0.0
gi|7706681 REV1-like isoform 1 [Homo sapiens] 2503 0.0
gi|154350220 DNA polymerase iota [Homo sapiens] 99 3e-20
gi|7705344 DNA-directed DNA polymerase kappa [Homo sapiens] 96 2e-19
gi|5729982 DNA-directed DNA polymerase eta [Homo sapiens] 69 2e-11
gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens] 40 0.011
gi|195972857 Rho/Rac guanine nucleotide exchange factor 18 isofo... 38 0.053
gi|41327769 Rho/Rac guanine nucleotide exchange factor 18 isofor... 38 0.053
gi|236462242 potassium voltage-gated channel, KQT-like subfamily... 38 0.069
gi|236462079 potassium voltage-gated channel, KQT-like subfamily... 38 0.069
gi|236461942 potassium voltage-gated channel, KQT-like subfamily... 38 0.069
gi|236461719 potassium voltage-gated channel, KQT-like subfamily... 38 0.069
gi|28373065 potassium voltage-gated channel, KQT-like subfamily,... 38 0.069
gi|194440660 topoisomerase (DNA) II binding protein 1 [Homo sapi... 38 0.069
gi|150170670 piccolo isoform 2 [Homo sapiens] 35 0.34
gi|150378539 piccolo isoform 1 [Homo sapiens] 35 0.34
gi|110611228 utrophin [Homo sapiens] 35 0.45
gi|7657218 bromodomain-containing protein 4 isoform short [Homo ... 35 0.59
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 35 0.59
gi|239757877 PREDICTED: FERM and PDZ domain containing 3 [Homo s... 34 0.76
gi|89060961 PREDICTED: FERM and PDZ domain containing 3 [Homo sa... 34 0.76
gi|89059963 PREDICTED: FERM and PDZ domain containing 3 [Homo sa... 34 0.76
gi|83367077 mucin 16 [Homo sapiens] 34 1.00
gi|239754668 PREDICTED: mucin 12 [Homo sapiens] 34 1.00
gi|239749217 PREDICTED: similar to Mucin-12, partial [Homo sapiens] 34 1.00
gi|239743293 PREDICTED: mucin 12 [Homo sapiens] 34 1.00
gi|239745855 PREDICTED: hypothetical protein XP_002343606 [Homo ... 33 1.3
gi|151301154 mucin 6, gastric [Homo sapiens] 33 1.7
gi|154091020 leucine-rich repeats and calponin homology (CH) dom... 33 2.2
gi|161016767 mucin 21 [Homo sapiens] 33 2.2
>gi|84043967 REV1-like isoform 2 [Homo sapiens]
Length = 1250
Score = 2507 bits (6498), Expect = 0.0
Identities = 1250/1250 (100%), Positives = 1250/1250 (100%)
Query: 1 MRRGGWRKRAENDGWETWGGYMAAKVQKLEEQFRSDAAMQKDGTSSTIFSGVAIYVNGYT 60
MRRGGWRKRAENDGWETWGGYMAAKVQKLEEQFRSDAAMQKDGTSSTIFSGVAIYVNGYT
Sbjct: 1 MRRGGWRKRAENDGWETWGGYMAAKVQKLEEQFRSDAAMQKDGTSSTIFSGVAIYVNGYT 60
Query: 61 DPSAEELRKLMMLHGGQYHVYYSRSKTTHIIATNLPNAKIKELKGEKVIRPEWIVESIKA 120
DPSAEELRKLMMLHGGQYHVYYSRSKTTHIIATNLPNAKIKELKGEKVIRPEWIVESIKA
Sbjct: 61 DPSAEELRKLMMLHGGQYHVYYSRSKTTHIIATNLPNAKIKELKGEKVIRPEWIVESIKA 120
Query: 121 GRLLSYIPYQLYTKQSSVQKGLSFNPVCRPEDPLPGPSNIAKQLNNRVNHIVKKIETENE 180
GRLLSYIPYQLYTKQSSVQKGLSFNPVCRPEDPLPGPSNIAKQLNNRVNHIVKKIETENE
Sbjct: 121 GRLLSYIPYQLYTKQSSVQKGLSFNPVCRPEDPLPGPSNIAKQLNNRVNHIVKKIETENE 180
Query: 181 VKVNGMNSWNEEDENNDFSFVDLEQTSPGRKQNGIPHPRGSTAIFNGHTPSSNGALKTQD 240
VKVNGMNSWNEEDENNDFSFVDLEQTSPGRKQNGIPHPRGSTAIFNGHTPSSNGALKTQD
Sbjct: 181 VKVNGMNSWNEEDENNDFSFVDLEQTSPGRKQNGIPHPRGSTAIFNGHTPSSNGALKTQD 240
Query: 241 CLVPMVNSVASRLSPAFSQEEDKAEKSSTDFRDCTLQQLQQSTRNTDALRNPHRTNSFSL 300
CLVPMVNSVASRLSPAFSQEEDKAEKSSTDFRDCTLQQLQQSTRNTDALRNPHRTNSFSL
Sbjct: 241 CLVPMVNSVASRLSPAFSQEEDKAEKSSTDFRDCTLQQLQQSTRNTDALRNPHRTNSFSL 300
Query: 301 SPLHSNTKINGAHHSTVQGPSSTKSTSSVSTFSKAAPSVPSKPSDCNFISNFYSHSRLHH 360
SPLHSNTKINGAHHSTVQGPSSTKSTSSVSTFSKAAPSVPSKPSDCNFISNFYSHSRLHH
Sbjct: 301 SPLHSNTKINGAHHSTVQGPSSTKSTSSVSTFSKAAPSVPSKPSDCNFISNFYSHSRLHH 360
Query: 361 ISMWKCELTEFVNTLQRQSNGIFPGREKLKKMKTGRSALVVTDTGDMSVLNSPRHQSCIM 420
ISMWKCELTEFVNTLQRQSNGIFPGREKLKKMKTGRSALVVTDTGDMSVLNSPRHQSCIM
Sbjct: 361 ISMWKCELTEFVNTLQRQSNGIFPGREKLKKMKTGRSALVVTDTGDMSVLNSPRHQSCIM 420
Query: 421 HVDMDCFFVSVGIRNRPDLKGKPVAVTSNRGTGRAPLRPGANPQLEWQYYQNKILKGKAD 480
HVDMDCFFVSVGIRNRPDLKGKPVAVTSNRGTGRAPLRPGANPQLEWQYYQNKILKGKAD
Sbjct: 421 HVDMDCFFVSVGIRNRPDLKGKPVAVTSNRGTGRAPLRPGANPQLEWQYYQNKILKGKAD 480
Query: 481 IPDSSLWENPDSAQANGIDSVLSRAEIASCSYEARQLGIKNGMFFGHAKQLCPNLQAVPY 540
IPDSSLWENPDSAQANGIDSVLSRAEIASCSYEARQLGIKNGMFFGHAKQLCPNLQAVPY
Sbjct: 481 IPDSSLWENPDSAQANGIDSVLSRAEIASCSYEARQLGIKNGMFFGHAKQLCPNLQAVPY 540
Query: 541 DFHAYKEVAQTLYETLASYTHNIEAVSCDEALVDITEILAETKLTPDEFANAVRMEIKDQ 600
DFHAYKEVAQTLYETLASYTHNIEAVSCDEALVDITEILAETKLTPDEFANAVRMEIKDQ
Sbjct: 541 DFHAYKEVAQTLYETLASYTHNIEAVSCDEALVDITEILAETKLTPDEFANAVRMEIKDQ 600
Query: 601 TKCAASVGIGSNILLARMATRKAKPDGQYHLKPEEVDDFIRGQLVTNLPGVGHSMESKLA 660
TKCAASVGIGSNILLARMATRKAKPDGQYHLKPEEVDDFIRGQLVTNLPGVGHSMESKLA
Sbjct: 601 TKCAASVGIGSNILLARMATRKAKPDGQYHLKPEEVDDFIRGQLVTNLPGVGHSMESKLA 660
Query: 661 SLGIKTCGDLQYMTMAKLQKEFGPKTGQMLYRFCRGLDDRPVRTEKERKSVSAEINYGIR 720
SLGIKTCGDLQYMTMAKLQKEFGPKTGQMLYRFCRGLDDRPVRTEKERKSVSAEINYGIR
Sbjct: 661 SLGIKTCGDLQYMTMAKLQKEFGPKTGQMLYRFCRGLDDRPVRTEKERKSVSAEINYGIR 720
Query: 721 FTQPKEAEAFLLSLSEEIQRRLEATGMKGKRLTLKIMVRKPGAPVETAKFGGHGICDNIA 780
FTQPKEAEAFLLSLSEEIQRRLEATGMKGKRLTLKIMVRKPGAPVETAKFGGHGICDNIA
Sbjct: 721 FTQPKEAEAFLLSLSEEIQRRLEATGMKGKRLTLKIMVRKPGAPVETAKFGGHGICDNIA 780
Query: 781 RTVTLDQATDNAKIIGKAMLNMFHTMKLNISDMRGVGIHVNQLVPTNLNPSTCPSRPSVQ 840
RTVTLDQATDNAKIIGKAMLNMFHTMKLNISDMRGVGIHVNQLVPTNLNPSTCPSRPSVQ
Sbjct: 781 RTVTLDQATDNAKIIGKAMLNMFHTMKLNISDMRGVGIHVNQLVPTNLNPSTCPSRPSVQ 840
Query: 841 SSHFPSGSYSVRDVFQVQKAKKSTEEEHKEVFRAAVDLEISSASRTCTFLPPFPAHLPTS 900
SSHFPSGSYSVRDVFQVQKAKKSTEEEHKEVFRAAVDLEISSASRTCTFLPPFPAHLPTS
Sbjct: 841 SSHFPSGSYSVRDVFQVQKAKKSTEEEHKEVFRAAVDLEISSASRTCTFLPPFPAHLPTS 900
Query: 901 PDTNKAESSGKWNGLHTPVSVQSRLNLSIEVPSPSQLDQSVLEALPPDLREQVEQVCAVQ 960
PDTNKAESSGKWNGLHTPVSVQSRLNLSIEVPSPSQLDQSVLEALPPDLREQVEQVCAVQ
Sbjct: 901 PDTNKAESSGKWNGLHTPVSVQSRLNLSIEVPSPSQLDQSVLEALPPDLREQVEQVCAVQ 960
Query: 961 QAESHGDKKKEPVNGCNTGILPQPVGTVLLQIPEPQESNSDAGINLIALPAFSQVDPEVF 1020
QAESHGDKKKEPVNGCNTGILPQPVGTVLLQIPEPQESNSDAGINLIALPAFSQVDPEVF
Sbjct: 961 QAESHGDKKKEPVNGCNTGILPQPVGTVLLQIPEPQESNSDAGINLIALPAFSQVDPEVF 1020
Query: 1021 AALPAELQRELKAAYDQRQRQGENSTHQQSASASVPKNPLLHLKAAVKEKKRNKKKKTIG 1080
AALPAELQRELKAAYDQRQRQGENSTHQQSASASVPKNPLLHLKAAVKEKKRNKKKKTIG
Sbjct: 1021 AALPAELQRELKAAYDQRQRQGENSTHQQSASASVPKNPLLHLKAAVKEKKRNKKKKTIG 1080
Query: 1081 SPKRIQSPLNNKLLNSPAKTLPGACGSPQKLIDGFLKHEGPPAEKPLEELSASTSGVPGL 1140
SPKRIQSPLNNKLLNSPAKTLPGACGSPQKLIDGFLKHEGPPAEKPLEELSASTSGVPGL
Sbjct: 1081 SPKRIQSPLNNKLLNSPAKTLPGACGSPQKLIDGFLKHEGPPAEKPLEELSASTSGVPGL 1140
Query: 1141 SSLQSDPAGCVRPPAPNLAGAVEFNDVKTLLREWITTISDPMEEDILQVVKYCTDLIEEK 1200
SSLQSDPAGCVRPPAPNLAGAVEFNDVKTLLREWITTISDPMEEDILQVVKYCTDLIEEK
Sbjct: 1141 SSLQSDPAGCVRPPAPNLAGAVEFNDVKTLLREWITTISDPMEEDILQVVKYCTDLIEEK 1200
Query: 1201 DLEKLDLVIKYMKRLMQQSVESVWNMAFDFILDNVQVVLQQTYGSTLKVT 1250
DLEKLDLVIKYMKRLMQQSVESVWNMAFDFILDNVQVVLQQTYGSTLKVT
Sbjct: 1201 DLEKLDLVIKYMKRLMQQSVESVWNMAFDFILDNVQVVLQQTYGSTLKVT 1250
>gi|7706681 REV1-like isoform 1 [Homo sapiens]
Length = 1251
Score = 2503 bits (6486), Expect = 0.0
Identities = 1250/1251 (99%), Positives = 1250/1251 (99%), Gaps = 1/1251 (0%)
Query: 1 MRRGGWRKRAENDGWETWGGYMAAKVQKLEEQFRSDAAMQKDGTSSTIFSGVAIYVNGYT 60
MRRGGWRKRAENDGWETWGGYMAAKVQKLEEQFRSDAAMQKDGTSSTIFSGVAIYVNGYT
Sbjct: 1 MRRGGWRKRAENDGWETWGGYMAAKVQKLEEQFRSDAAMQKDGTSSTIFSGVAIYVNGYT 60
Query: 61 DPSAEELRKLMMLHGGQYHVYYSRSKTTHIIATNLPNAKIKELKGEKVIRPEWIVESIKA 120
DPSAEELRKLMMLHGGQYHVYYSRSKTTHIIATNLPNAKIKELKGEKVIRPEWIVESIKA
Sbjct: 61 DPSAEELRKLMMLHGGQYHVYYSRSKTTHIIATNLPNAKIKELKGEKVIRPEWIVESIKA 120
Query: 121 GRLLSYIPYQLYTKQSSVQKGLSFNPVCRPEDPLPGPSNIAKQLNNRVNHIVKKIETENE 180
GRLLSYIPYQLYTKQSSVQKGLSFNPVCRPEDPLPGPSNIAKQLNNRVNHIVKKIETENE
Sbjct: 121 GRLLSYIPYQLYTKQSSVQKGLSFNPVCRPEDPLPGPSNIAKQLNNRVNHIVKKIETENE 180
Query: 181 VKVNGMNSWNEEDENNDFSFVDLEQTSPGRKQNGIPHPRGSTAIFNGHTPSSNGALKTQD 240
VKVNGMNSWNEEDENNDFSFVDLEQTSPGRKQNGIPHPRGSTAIFNGHTPSSNGALKTQD
Sbjct: 181 VKVNGMNSWNEEDENNDFSFVDLEQTSPGRKQNGIPHPRGSTAIFNGHTPSSNGALKTQD 240
Query: 241 CLVPMVNSVASRLSPAFSQEEDKAEKSSTDFRDCTLQQLQQSTRNTDALRNPHRTNSFSL 300
CLVPMVNSVASRLSPAFSQEEDKAEKSSTDFRDCTLQQLQQSTRNTDALRNPHRTNSFSL
Sbjct: 241 CLVPMVNSVASRLSPAFSQEEDKAEKSSTDFRDCTLQQLQQSTRNTDALRNPHRTNSFSL 300
Query: 301 SPLHSNTKINGAHHSTVQGPSSTKSTSSVSTFSKAAPSVPSKPSDCNFISNFYSHSRLHH 360
SPLHSNTKINGAHHSTVQGPSSTKSTSSVSTFSKAAPSVPSKPSDCNFISNFYSHSRLHH
Sbjct: 301 SPLHSNTKINGAHHSTVQGPSSTKSTSSVSTFSKAAPSVPSKPSDCNFISNFYSHSRLHH 360
Query: 361 ISMWKCELTEFVNTLQRQSNGIFPGREKLKKMKTGRSALVVTDTGDMSVLNSPRHQSCIM 420
ISMWKCELTEFVNTLQRQSNGIFPGREKLKKMKTGRSALVVTDTGDMSVLNSPRHQSCIM
Sbjct: 361 ISMWKCELTEFVNTLQRQSNGIFPGREKLKKMKTGRSALVVTDTGDMSVLNSPRHQSCIM 420
Query: 421 HVDMDCFFVSVGIRNRPDLKGKPVAVTSNRGTGRAPLRPGANPQLEWQYYQNKILKGKA- 479
HVDMDCFFVSVGIRNRPDLKGKPVAVTSNRGTGRAPLRPGANPQLEWQYYQNKILKGKA
Sbjct: 421 HVDMDCFFVSVGIRNRPDLKGKPVAVTSNRGTGRAPLRPGANPQLEWQYYQNKILKGKAA 480
Query: 480 DIPDSSLWENPDSAQANGIDSVLSRAEIASCSYEARQLGIKNGMFFGHAKQLCPNLQAVP 539
DIPDSSLWENPDSAQANGIDSVLSRAEIASCSYEARQLGIKNGMFFGHAKQLCPNLQAVP
Sbjct: 481 DIPDSSLWENPDSAQANGIDSVLSRAEIASCSYEARQLGIKNGMFFGHAKQLCPNLQAVP 540
Query: 540 YDFHAYKEVAQTLYETLASYTHNIEAVSCDEALVDITEILAETKLTPDEFANAVRMEIKD 599
YDFHAYKEVAQTLYETLASYTHNIEAVSCDEALVDITEILAETKLTPDEFANAVRMEIKD
Sbjct: 541 YDFHAYKEVAQTLYETLASYTHNIEAVSCDEALVDITEILAETKLTPDEFANAVRMEIKD 600
Query: 600 QTKCAASVGIGSNILLARMATRKAKPDGQYHLKPEEVDDFIRGQLVTNLPGVGHSMESKL 659
QTKCAASVGIGSNILLARMATRKAKPDGQYHLKPEEVDDFIRGQLVTNLPGVGHSMESKL
Sbjct: 601 QTKCAASVGIGSNILLARMATRKAKPDGQYHLKPEEVDDFIRGQLVTNLPGVGHSMESKL 660
Query: 660 ASLGIKTCGDLQYMTMAKLQKEFGPKTGQMLYRFCRGLDDRPVRTEKERKSVSAEINYGI 719
ASLGIKTCGDLQYMTMAKLQKEFGPKTGQMLYRFCRGLDDRPVRTEKERKSVSAEINYGI
Sbjct: 661 ASLGIKTCGDLQYMTMAKLQKEFGPKTGQMLYRFCRGLDDRPVRTEKERKSVSAEINYGI 720
Query: 720 RFTQPKEAEAFLLSLSEEIQRRLEATGMKGKRLTLKIMVRKPGAPVETAKFGGHGICDNI 779
RFTQPKEAEAFLLSLSEEIQRRLEATGMKGKRLTLKIMVRKPGAPVETAKFGGHGICDNI
Sbjct: 721 RFTQPKEAEAFLLSLSEEIQRRLEATGMKGKRLTLKIMVRKPGAPVETAKFGGHGICDNI 780
Query: 780 ARTVTLDQATDNAKIIGKAMLNMFHTMKLNISDMRGVGIHVNQLVPTNLNPSTCPSRPSV 839
ARTVTLDQATDNAKIIGKAMLNMFHTMKLNISDMRGVGIHVNQLVPTNLNPSTCPSRPSV
Sbjct: 781 ARTVTLDQATDNAKIIGKAMLNMFHTMKLNISDMRGVGIHVNQLVPTNLNPSTCPSRPSV 840
Query: 840 QSSHFPSGSYSVRDVFQVQKAKKSTEEEHKEVFRAAVDLEISSASRTCTFLPPFPAHLPT 899
QSSHFPSGSYSVRDVFQVQKAKKSTEEEHKEVFRAAVDLEISSASRTCTFLPPFPAHLPT
Sbjct: 841 QSSHFPSGSYSVRDVFQVQKAKKSTEEEHKEVFRAAVDLEISSASRTCTFLPPFPAHLPT 900
Query: 900 SPDTNKAESSGKWNGLHTPVSVQSRLNLSIEVPSPSQLDQSVLEALPPDLREQVEQVCAV 959
SPDTNKAESSGKWNGLHTPVSVQSRLNLSIEVPSPSQLDQSVLEALPPDLREQVEQVCAV
Sbjct: 901 SPDTNKAESSGKWNGLHTPVSVQSRLNLSIEVPSPSQLDQSVLEALPPDLREQVEQVCAV 960
Query: 960 QQAESHGDKKKEPVNGCNTGILPQPVGTVLLQIPEPQESNSDAGINLIALPAFSQVDPEV 1019
QQAESHGDKKKEPVNGCNTGILPQPVGTVLLQIPEPQESNSDAGINLIALPAFSQVDPEV
Sbjct: 961 QQAESHGDKKKEPVNGCNTGILPQPVGTVLLQIPEPQESNSDAGINLIALPAFSQVDPEV 1020
Query: 1020 FAALPAELQRELKAAYDQRQRQGENSTHQQSASASVPKNPLLHLKAAVKEKKRNKKKKTI 1079
FAALPAELQRELKAAYDQRQRQGENSTHQQSASASVPKNPLLHLKAAVKEKKRNKKKKTI
Sbjct: 1021 FAALPAELQRELKAAYDQRQRQGENSTHQQSASASVPKNPLLHLKAAVKEKKRNKKKKTI 1080
Query: 1080 GSPKRIQSPLNNKLLNSPAKTLPGACGSPQKLIDGFLKHEGPPAEKPLEELSASTSGVPG 1139
GSPKRIQSPLNNKLLNSPAKTLPGACGSPQKLIDGFLKHEGPPAEKPLEELSASTSGVPG
Sbjct: 1081 GSPKRIQSPLNNKLLNSPAKTLPGACGSPQKLIDGFLKHEGPPAEKPLEELSASTSGVPG 1140
Query: 1140 LSSLQSDPAGCVRPPAPNLAGAVEFNDVKTLLREWITTISDPMEEDILQVVKYCTDLIEE 1199
LSSLQSDPAGCVRPPAPNLAGAVEFNDVKTLLREWITTISDPMEEDILQVVKYCTDLIEE
Sbjct: 1141 LSSLQSDPAGCVRPPAPNLAGAVEFNDVKTLLREWITTISDPMEEDILQVVKYCTDLIEE 1200
Query: 1200 KDLEKLDLVIKYMKRLMQQSVESVWNMAFDFILDNVQVVLQQTYGSTLKVT 1250
KDLEKLDLVIKYMKRLMQQSVESVWNMAFDFILDNVQVVLQQTYGSTLKVT
Sbjct: 1201 KDLEKLDLVIKYMKRLMQQSVESVWNMAFDFILDNVQVVLQQTYGSTLKVT 1251
>gi|154350220 DNA polymerase iota [Homo sapiens]
Length = 740
Score = 98.6 bits (244), Expect = 3e-20
Identities = 97/388 (25%), Positives = 158/388 (40%), Gaps = 94/388 (24%)
Query: 409 VLNSPRHQS-CIMHVDMDCFFVSVGIRNRPDLKGKPVAVTSNRGTGRAPLRPGANPQLEW 467
VL +P S I+HVD+DCF+ V + + P+LK KP+ V
Sbjct: 44 VLPTPNASSRVIVHVDLDCFYAQVEMISNPELKDKPLGV--------------------- 82
Query: 468 QYYQNKILKGKADIPDSSLWENPDSAQANGIDSVLSRAEIASCSYEARQLGIKNGMFFGH 527
Q K L + +C+YEAR+LG+K M
Sbjct: 83 ---QQKYL-------------------------------VVTCNYEARKLGVKKLMNVRD 108
Query: 528 AKQLCPNLQAVP-YDFHAYKEVAQTLYETLASYTHNIEAVSCDEALVDITEILAET--KL 584
AK+ CP L V D Y+E++ + E L ++ +E + DE VD+TE++ + +L
Sbjct: 109 AKEKCPQLVLVNGEDLTRYREMSYKVTELLEEFSPVVERLGFDENFVDLTEMVEKRLQQL 168
Query: 585 TPDEF-------------------------------ANAVRMEIKDQTKCAASVGIGSNI 613
DE A +R + +Q G+ SN
Sbjct: 169 QSDELSAVTVSGHVYNNQSINLLDVLHIRLLVGSQIAAEMREAMYNQLGLTGCAGVASNK 228
Query: 614 LLARMATRKAKPDGQYHLKPEEVDDFIRG-QLVTNLPGVGHSMESKLASLGIKTCGDLQY 672
LLA++ + KP+ Q L PE I + +PG+G+ L +LGI + DLQ
Sbjct: 229 LLAKLVSGVFKPNQQTVLLPESCQHLIHSLNHIKEIPGIGYKTAKCLEALGINSVRDLQT 288
Query: 673 MTMAKLQKEFGPKTGQMLYRFCRGLDDRPVRTEKERKSVSAEINYGIRFTQPKEAEAFLL 732
+ L+KE G Q + + G D+ PV +S S E ++ + + EA+ +
Sbjct: 289 FSPKILEKELGISVAQRIQKLSFGEDNSPVILSGPPQSFSEEDSFK-KCSSEVEAKNKIE 347
Query: 733 SLSEEIQRRLEATGMKGKRLTLKIMVRK 760
L + R+ G K T+++++R+
Sbjct: 348 ELLASLLNRVCQDGRKPH--TVRLIIRR 373
>gi|7705344 DNA-directed DNA polymerase kappa [Homo sapiens]
Length = 870
Score = 95.9 bits (237), Expect = 2e-19
Identities = 101/394 (25%), Positives = 170/394 (43%), Gaps = 46/394 (11%)
Query: 396 RSALVVTDTGDMSVLNSPRHQSCIMHVDMDCFFVSVGIRNRPDLKGKPVAV-------TS 448
R A + D M + S + I+H+DMD F+ +V +R+ P+LK KP+AV TS
Sbjct: 80 RKAQLQVDRFAMELEQSRNLSNTIVHIDMDAFYAAVEMRDNPELKDKPIAVGSMSMLSTS 139
Query: 449 NRGTGRAPLR---PG-----ANPQL--------EWQYYQNKILKGKADIPDSSLWENPDS 492
N R +R PG PQL +++ ++ + AD + + + D
Sbjct: 140 NYHARRFGVRAAMPGFIAKRLCPQLIIVPPNFDKYRAVSKEVKEILADYDPNFMAMSLDE 199
Query: 493 AQANGIDSVLSRAEIASCSYEARQLGIKNGMFFGHAKQLCPNLQAVPYDFHAYKEVAQTL 552
A N + R + R+ IK G + P + H + ++ L
Sbjct: 200 AYLNITKHLEERQNWPE---DKRRYFIKMGSSVENDN---PGKEVNKLSEHE-RSISPLL 252
Query: 553 YETLAS--------YTHNIEAVSCDEALVDITEILAETKLTPDEFANAVRMEIKDQTKCA 604
+E S + N E + + L + ++ T + E +R I+ +T
Sbjct: 253 FEESPSDVQPPGDPFQVNFEEQNNPQILQN--SVVFGT--SAQEVVKEIRFRIEQKTTLT 308
Query: 605 ASVGIGSNILLARMATRKAKPDGQYHLKP--EEVDDFIRGQLVTNLPGVGHSMESKLASL 662
AS GI N +LA++ + K KP+GQY + P + V DFI+ + + G+G E L +L
Sbjct: 309 ASAGIAPNTMLAKVCSDKNKPNGQYQILPNRQAVMDFIKDLPIRKVSGIGKVTEKMLKAL 368
Query: 663 GIKTCGDLQYMTMAKLQKEFGPKTGQMLYRFCRGLDDRPVRTEKERKSVSAEINYGIRFT 722
GI TC +L Y A L F + GL + + ERKS+S E +
Sbjct: 369 GIITCTEL-YQQRALLSLLFSETSWHYFLHISLGLGSTHLTRDGERKSMSVERTFS-EIN 426
Query: 723 QPKEAEAFLLSLSEEIQRRLEATGMKGKRLTLKI 756
+ +E + L E+ + L+ +KG+ +T+K+
Sbjct: 427 KAEEQYSLCQELCSELAQDLQKERLKGRTVTIKL 460
>gi|5729982 DNA-directed DNA polymerase eta [Homo sapiens]
Length = 713
Score = 69.3 bits (168), Expect = 2e-11
Identities = 45/169 (26%), Positives = 81/169 (47%), Gaps = 3/169 (1%)
Query: 593 VRMEIKDQTKCAASVGIGSNILLARMATRKAKPDGQYHLKPEEVDDFIRGQLVTNLPGVG 652
+R I+ +T S GI N +LA++A KP+ Q + V + + +G
Sbjct: 200 MRAAIERETGFQCSAGISHNKVLAKLACGLNKPNRQTLVSHGSVPQLFSQMPIRKIRSLG 259
Query: 653 HSM-ESKLASLGIKTCGDLQYMTMAKLQKEFGPKTGQMLYRFCRGLDDRPVRTEKERKSV 711
+ S + LGI+ G+L T ++LQ FG K G LY CRG++ PV+ + K++
Sbjct: 260 GKLGASVIEILGIEYMGELTQFTESQLQSHFGEKNGSWLYAMCRGIEHDPVKPRQLPKTI 319
Query: 712 SAEINY--GIRFTQPKEAEAFLLSLSEEIQRRLEATGMKGKRLTLKIMV 758
N+ ++ + +LL L++E++ RL R+ +++V
Sbjct: 320 GCSKNFPGKTALATREQVQWWLLQLAQELEERLTKDRNDNDRVATQLVV 368
Score = 51.2 bits (121), Expect = 6e-06
Identities = 47/167 (28%), Positives = 62/167 (37%), Gaps = 58/167 (34%)
Query: 422 VDMDCFFVSVGIRNRPDLKGKPVAVTSNRGTGRAPLRPGANPQLEWQYYQNKILKGKADI 481
VDMDCFFV V R P L+ KP AV Q K KG
Sbjct: 12 VDMDCFFVQVEQRQNPHLRNKPCAVV-----------------------QYKSWKGGG-- 46
Query: 482 PDSSLWENPDSAQANGIDSVLSRAEIASCSYEARQLGIKNGMFFGHAKQLCPNLQAVPY- 540
I + SYEAR G+ M+ AK+LCP+L
Sbjct: 47 -------------------------IIAVSYEARAFGVTRSMWADDAKKLCPDLLLAQVR 81
Query: 541 ------DFHAYKEVAQTLYETLASYTHNIEAVSCDEALVDITEILAE 581
+ Y+E + + E ++ + IE S DEA VD+T + E
Sbjct: 82 ESRGKANLTKYREASVEVMEIMSRFA-VIERASIDEAYVDLTSAVQE 127
>gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens]
Length = 4374
Score = 40.4 bits (93), Expect = 0.011
Identities = 36/140 (25%), Positives = 59/140 (42%), Gaps = 32/140 (22%)
Query: 934 PSQLDQSVLEALPPDLREQVEQVCAVQQAESHGDKKKEPVNGCNTGILPQPVGTVLLQIP 993
P +D S L ALP D+R +V Q GI P P T
Sbjct: 2965 PEGVDPSFLAALPDDIRREVLQN--------------------QLGIRP-PTRTA----- 2998
Query: 994 EPQESNSDAGINLIALPAFSQVDPEVFAALPAELQRELKAAYDQRQRQGENSTHQQSASA 1053
S + + ++ P ++V PE AALP +Q E+ A Q++ E + Q+AS+
Sbjct: 2999 ---PSTNSSAPAVVGNPGVTEVSPEFLAALPPAIQEEVLAQQRAEQQRRELA---QNASS 3052
Query: 1054 SVPKNPLLHLKAAVKEKKRN 1073
P +P+ ++ + +R+
Sbjct: 3053 DTPMDPVTFIQTLPSDLRRS 3072
Score = 31.6 bits (70), Expect = 5.0
Identities = 41/177 (23%), Positives = 67/177 (37%), Gaps = 32/177 (18%)
Query: 894 PAHLPTSPDTNKAESSGKWNGLHTPVSVQSRLNLSIEV----PSPSQLDQSVLEALPPDL 949
P+ L PD + E G+ P N S P +++ L ALPP +
Sbjct: 2970 PSFLAALPDDIRREVLQNQLGIRPPTRTAPSTNSSAPAVVGNPGVTEVSPEFLAALPPAI 3029
Query: 950 REQVEQVCAVQQAESHGDKKKEPVNGCNTGILPQPVGTVLLQIPEPQESNSDAGINLIAL 1009
+ E+V A Q+AE +++E ++ PV T + +P +
Sbjct: 3030 Q---EEVLAQQRAE---QQRRELAQNASSDTPMDPV-TFIQTLPSD-----------LRR 3071
Query: 1010 PAFSQVDPEVFAALPAELQRE---LKAAYDQRQRQ-------GENSTHQQSASASVP 1056
++ V A +P ++ E L+ + RQRQ G +ST SA P
Sbjct: 3072 SVLEDMEDSVLAVMPPDIAAEAQALRREQEARQRQLMHERLFGHSSTSALSAILRSP 3128
>gi|195972857 Rho/Rac guanine nucleotide exchange factor 18 isoform b
[Homo sapiens]
Length = 1173
Score = 38.1 bits (87), Expect = 0.053
Identities = 55/224 (24%), Positives = 81/224 (36%), Gaps = 40/224 (17%)
Query: 944 ALPPDLREQVEQVCAVQQAESHGDK-KKEPVNGCNTGILPQPVGTVLLQIPE-------P 995
ALPPD A Q SH E + G +LP VG + PE P
Sbjct: 964 ALPPD-------TLAEAQPPSHPPSFNGEGLEGPRVSMLPSGVGPEYAERPEVARRDSAP 1016
Query: 996 QESN---SDAGINLIALPAFSQVDPEVFAALPAELQRELKAAYDQRQRQGENSTHQQSAS 1052
E+ SD I L++ Q V +P +L K D+ + + + SAS
Sbjct: 1017 TENRLAKSDVPIQLLSATNQFQRQAAVQQQIPTKLAASTKGGKDKGGKSRGSQRWESSAS 1076
Query: 1053 ASVPKNPLLHLKAAVKEKKRNKKKKTIGSPKRIQSPLNNKLLNSPAKTLPGACGSPQKLI 1112
+ + LL+ K K++ ++ ++++ SP+ LPG
Sbjct: 1077 FDLKQQLLLN-KLMGKDESTSRNRRSL-------SPI-----------LPGRHSPAPPPD 1117
Query: 1113 DGFLKHEGPPAEKPLEELSASTSGVPGLSSLQSDPAGCVRPPAP 1156
GF PPA+ P E S G + L PA P P
Sbjct: 1118 PGFPAPSPPPADSPSEGFSLKAGGT---ALLPGPPAPSPLPATP 1158
>gi|41327769 Rho/Rac guanine nucleotide exchange factor 18 isoform a
[Homo sapiens]
Length = 1015
Score = 38.1 bits (87), Expect = 0.053
Identities = 55/224 (24%), Positives = 81/224 (36%), Gaps = 40/224 (17%)
Query: 944 ALPPDLREQVEQVCAVQQAESHGDK-KKEPVNGCNTGILPQPVGTVLLQIPE-------P 995
ALPPD A Q SH E + G +LP VG + PE P
Sbjct: 806 ALPPD-------TLAEAQPPSHPPSFNGEGLEGPRVSMLPSGVGPEYAERPEVARRDSAP 858
Query: 996 QESN---SDAGINLIALPAFSQVDPEVFAALPAELQRELKAAYDQRQRQGENSTHQQSAS 1052
E+ SD I L++ Q V +P +L K D+ + + + SAS
Sbjct: 859 TENRLAKSDVPIQLLSATNQFQRQAAVQQQIPTKLAASTKGGKDKGGKSRGSQRWESSAS 918
Query: 1053 ASVPKNPLLHLKAAVKEKKRNKKKKTIGSPKRIQSPLNNKLLNSPAKTLPGACGSPQKLI 1112
+ + LL+ K K++ ++ ++++ SP+ LPG
Sbjct: 919 FDLKQQLLLN-KLMGKDESTSRNRRSL-------SPI-----------LPGRHSPAPPPD 959
Query: 1113 DGFLKHEGPPAEKPLEELSASTSGVPGLSSLQSDPAGCVRPPAP 1156
GF PPA+ P E S G + L PA P P
Sbjct: 960 PGFPAPSPPPADSPSEGFSLKAGGT---ALLPGPPAPSPLPATP 1000
>gi|236462242 potassium voltage-gated channel, KQT-like subfamily,
member 5 isoform 5 [Homo sapiens]
Length = 822
Score = 37.7 bits (86), Expect = 0.069
Identities = 52/229 (22%), Positives = 89/229 (38%), Gaps = 25/229 (10%)
Query: 813 MRGVGIHVNQLVPTNLNPSTCPSRPSVQSSHFPSGSYSVRD-VFQVQKAKKSTEEEHK-- 869
++ + V+Q++ S SR + + H + S+ V +V+K +S E +
Sbjct: 454 IKSLQTRVDQILGKGQITSDKKSREKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCL 513
Query: 870 -EVFRAAVDLEISSASRTCTF-LPPFPAHLPT---SPDTNKAESSGKWNGLHTPVSVQSR 924
++++ + +SA +F +PPF + SP +K S N S +
Sbjct: 514 LDIYQQVLRKGSASALALASFQIPPFECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSAN 573
Query: 925 LNLSIE-VPSPSQLDQSVLEALPPDLREQVEQVCAVQQAESHGDKKKEPVNGCNTGILPQ 983
++ ++ + +P++ AL P + Q QV Q S N NT P+
Sbjct: 574 ISRGLQFILTPNEFSAQTFYALSPTMHSQATQVPISQSDGSAVAATNTIANQINTA--PK 631
Query: 984 PVGTVLLQIPEPQESNSDAGINLIALPAFSQVD-PEVFAALPAELQREL 1031
P LQIP P LPA + PE PA LQ +
Sbjct: 632 PAAPTTLQIPPP-------------LPAIKHLPRPETLHPNPAGLQESI 667
>gi|236462079 potassium voltage-gated channel, KQT-like subfamily,
member 5 isoform 4 [Homo sapiens]
Length = 951
Score = 37.7 bits (86), Expect = 0.069
Identities = 52/229 (22%), Positives = 89/229 (38%), Gaps = 25/229 (10%)
Query: 813 MRGVGIHVNQLVPTNLNPSTCPSRPSVQSSHFPSGSYSVRD-VFQVQKAKKSTEEEHK-- 869
++ + V+Q++ S SR + + H + S+ V +V+K +S E +
Sbjct: 583 IKSLQTRVDQILGKGQITSDKKSREKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCL 642
Query: 870 -EVFRAAVDLEISSASRTCTF-LPPFPAHLPT---SPDTNKAESSGKWNGLHTPVSVQSR 924
++++ + +SA +F +PPF + SP +K S N S +
Sbjct: 643 LDIYQQVLRKGSASALALASFQIPPFECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSAN 702
Query: 925 LNLSIE-VPSPSQLDQSVLEALPPDLREQVEQVCAVQQAESHGDKKKEPVNGCNTGILPQ 983
++ ++ + +P++ AL P + Q QV Q S N NT P+
Sbjct: 703 ISRGLQFILTPNEFSAQTFYALSPTMHSQATQVPISQSDGSAVAATNTIANQINTA--PK 760
Query: 984 PVGTVLLQIPEPQESNSDAGINLIALPAFSQVD-PEVFAALPAELQREL 1031
P LQIP P LPA + PE PA LQ +
Sbjct: 761 PAAPTTLQIPPP-------------LPAIKHLPRPETLHPNPAGLQESI 796
>gi|236461942 potassium voltage-gated channel, KQT-like subfamily,
member 5 isoform 3 [Homo sapiens]
Length = 942
Score = 37.7 bits (86), Expect = 0.069
Identities = 52/229 (22%), Positives = 89/229 (38%), Gaps = 25/229 (10%)
Query: 813 MRGVGIHVNQLVPTNLNPSTCPSRPSVQSSHFPSGSYSVRD-VFQVQKAKKSTEEEHK-- 869
++ + V+Q++ S SR + + H + S+ V +V+K +S E +
Sbjct: 574 IKSLQTRVDQILGKGQITSDKKSREKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCL 633
Query: 870 -EVFRAAVDLEISSASRTCTF-LPPFPAHLPT---SPDTNKAESSGKWNGLHTPVSVQSR 924
++++ + +SA +F +PPF + SP +K S N S +
Sbjct: 634 LDIYQQVLRKGSASALALASFQIPPFECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSAN 693
Query: 925 LNLSIE-VPSPSQLDQSVLEALPPDLREQVEQVCAVQQAESHGDKKKEPVNGCNTGILPQ 983
++ ++ + +P++ AL P + Q QV Q S N NT P+
Sbjct: 694 ISRGLQFILTPNEFSAQTFYALSPTMHSQATQVPISQSDGSAVAATNTIANQINTA--PK 751
Query: 984 PVGTVLLQIPEPQESNSDAGINLIALPAFSQVD-PEVFAALPAELQREL 1031
P LQIP P LPA + PE PA LQ +
Sbjct: 752 PAAPTTLQIPPP-------------LPAIKHLPRPETLHPNPAGLQESI 787
>gi|236461719 potassium voltage-gated channel, KQT-like subfamily,
member 5 isoform 2 [Homo sapiens]
Length = 923
Score = 37.7 bits (86), Expect = 0.069
Identities = 52/229 (22%), Positives = 89/229 (38%), Gaps = 25/229 (10%)
Query: 813 MRGVGIHVNQLVPTNLNPSTCPSRPSVQSSHFPSGSYSVRD-VFQVQKAKKSTEEEHK-- 869
++ + V+Q++ S SR + + H + S+ V +V+K +S E +
Sbjct: 555 IKSLQTRVDQILGKGQITSDKKSREKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCL 614
Query: 870 -EVFRAAVDLEISSASRTCTF-LPPFPAHLPT---SPDTNKAESSGKWNGLHTPVSVQSR 924
++++ + +SA +F +PPF + SP +K S N S +
Sbjct: 615 LDIYQQVLRKGSASALALASFQIPPFECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSAN 674
Query: 925 LNLSIE-VPSPSQLDQSVLEALPPDLREQVEQVCAVQQAESHGDKKKEPVNGCNTGILPQ 983
++ ++ + +P++ AL P + Q QV Q S N NT P+
Sbjct: 675 ISRGLQFILTPNEFSAQTFYALSPTMHSQATQVPISQSDGSAVAATNTIANQINTA--PK 732
Query: 984 PVGTVLLQIPEPQESNSDAGINLIALPAFSQVD-PEVFAALPAELQREL 1031
P LQIP P LPA + PE PA LQ +
Sbjct: 733 PAAPTTLQIPPP-------------LPAIKHLPRPETLHPNPAGLQESI 768
>gi|28373065 potassium voltage-gated channel, KQT-like subfamily,
member 5 isoform 1 [Homo sapiens]
Length = 932
Score = 37.7 bits (86), Expect = 0.069
Identities = 52/229 (22%), Positives = 89/229 (38%), Gaps = 25/229 (10%)
Query: 813 MRGVGIHVNQLVPTNLNPSTCPSRPSVQSSHFPSGSYSVRD-VFQVQKAKKSTEEEHK-- 869
++ + V+Q++ S SR + + H + S+ V +V+K +S E +
Sbjct: 564 IKSLQTRVDQILGKGQITSDKKSREKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCL 623
Query: 870 -EVFRAAVDLEISSASRTCTF-LPPFPAHLPT---SPDTNKAESSGKWNGLHTPVSVQSR 924
++++ + +SA +F +PPF + SP +K S N S +
Sbjct: 624 LDIYQQVLRKGSASALALASFQIPPFECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSAN 683
Query: 925 LNLSIE-VPSPSQLDQSVLEALPPDLREQVEQVCAVQQAESHGDKKKEPVNGCNTGILPQ 983
++ ++ + +P++ AL P + Q QV Q S N NT P+
Sbjct: 684 ISRGLQFILTPNEFSAQTFYALSPTMHSQATQVPISQSDGSAVAATNTIANQINTA--PK 741
Query: 984 PVGTVLLQIPEPQESNSDAGINLIALPAFSQVD-PEVFAALPAELQREL 1031
P LQIP P LPA + PE PA LQ +
Sbjct: 742 PAAPTTLQIPPP-------------LPAIKHLPRPETLHPNPAGLQESI 777
>gi|194440660 topoisomerase (DNA) II binding protein 1 [Homo
sapiens]
Length = 1522
Score = 37.7 bits (86), Expect = 0.069
Identities = 23/76 (30%), Positives = 36/76 (47%), Gaps = 2/76 (2%)
Query: 48 IFSGVAIYVNGYTDPSAEELRKLMMLHGGQYHVYYSRSKTTHIIATNLPNAKIKELKGEK 107
IF G I V G +E+++L + HGGQY ++ TH+I K + K
Sbjct: 199 IFLGCIICVTGLCGLDRKEVQQLTVKHGGQYMGQLKMNECTHLIVQEPKGQKYECAKRWN 258
Query: 108 V--IRPEWIVESIKAG 121
V + +W +SI+ G
Sbjct: 259 VHCVTTQWFFDSIEKG 274
Score = 34.3 bits (77), Expect = 0.76
Identities = 25/104 (24%), Positives = 48/104 (46%), Gaps = 8/104 (7%)
Query: 48 IFSGVAIYVNGYTDPSAEELRKLMMLHGGQYHVYYSRSKTTHIIATNLPNAKIKELKGEK 107
+ G IY+ G++ ++LR+L+ GG TH+I + + ++K+ +
Sbjct: 358 LLDGCRIYLCGFSGRKLDKLRRLIN-SGGGVRFNQLNEDVTHVIVGDYDD-ELKQFWNKS 415
Query: 108 VIRP-----EWIVESIKAGRLLSYIPYQLYTKQSSVQKGLSFNP 146
RP +W++E G +LS PY ++ V+ +S P
Sbjct: 416 AHRPHVVGAKWLLECFSKGYMLSEEPY-IHANYQPVEIPVSHKP 458
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 35.4 bits (80), Expect = 0.34
Identities = 49/185 (26%), Positives = 76/185 (41%), Gaps = 29/185 (15%)
Query: 957 CAVQQAESH--GDKKKEPVNGCNTGILPQPVGTVLLQIPEPQESNSDAGINLIALPAFSQ 1014
C Q+A S GD +K P P P G +P P ES+S + +
Sbjct: 1109 CQTQRAISGQLGDIRKMP---------PAPSGPKASPMPVPTESSSQKTAVPPQVKLVKK 1159
Query: 1015 VDPEVFAALPAELQRELKAAYDQR---------QRQGENSTHQQSASASVPKNPLLHLKA 1065
+ EV + ++K Q+Q E+ + ASA K PL K
Sbjct: 1160 QEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKK 1219
Query: 1066 AV--KEKKRNKKKKTIGSPKRIQSPLNNKLLNSPAKTLPGACGSPQKLIDGFLKHEGPPA 1123
+ +EK R+++KK + K+ +P + KLL AKT +P++ LK + A
Sbjct: 1220 LIPEEEKIRSEEKKPLLEEKK-PTPEDKKLL-PEAKT-----SAPEEQKHDLLKSQVQIA 1272
Query: 1124 EKPLE 1128
E+ LE
Sbjct: 1273 EEKLE 1277
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 35.4 bits (80), Expect = 0.34
Identities = 49/185 (26%), Positives = 76/185 (41%), Gaps = 29/185 (15%)
Query: 957 CAVQQAESH--GDKKKEPVNGCNTGILPQPVGTVLLQIPEPQESNSDAGINLIALPAFSQ 1014
C Q+A S GD +K P P P G +P P ES+S + +
Sbjct: 1109 CQTQRAISGQLGDIRKMP---------PAPSGPKASPMPVPTESSSQKTAVPPQVKLVKK 1159
Query: 1015 VDPEVFAALPAELQRELKAAYDQR---------QRQGENSTHQQSASASVPKNPLLHLKA 1065
+ EV + ++K Q+Q E+ + ASA K PL K
Sbjct: 1160 QEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKK 1219
Query: 1066 AV--KEKKRNKKKKTIGSPKRIQSPLNNKLLNSPAKTLPGACGSPQKLIDGFLKHEGPPA 1123
+ +EK R+++KK + K+ +P + KLL AKT +P++ LK + A
Sbjct: 1220 LIPEEEKIRSEEKKPLLEEKK-PTPEDKKLL-PEAKT-----SAPEEQKHDLLKSQVQIA 1272
Query: 1124 EKPLE 1128
E+ LE
Sbjct: 1273 EEKLE 1277
>gi|110611228 utrophin [Homo sapiens]
Length = 3433
Score = 35.0 bits (79), Expect = 0.45
Identities = 45/207 (21%), Positives = 78/207 (37%), Gaps = 29/207 (14%)
Query: 151 EDPLPGPSNIAKQLNNRVNHIVKKIETENEVKVNGMNSWNEEDENNDFSFVDLEQTSPGR 210
E P+ P + A+ I+K +E E ++ + + EE++ N V+ EQ
Sbjct: 3239 ESPVSQPQSPAQ--------ILKSVEREERGELERIIADLEEEQRN--LQVEYEQLKDQH 3288
Query: 211 KQNGIPHPRGSTAIFNGHTPSSNGALKTQDCLVPMVNSVASRLSPAFSQEEDKAEKSSTD 270
+ G+P +I + H S + L + ++ RL ED ++ +
Sbjct: 3289 LRRGLPVGSPPESIISPHHTSEDSELIAE---AKLLRQHKGRLEARMQILEDHNKQLESQ 3345
Query: 271 FRDCTLQQLQQSTRNTDALRN-------PHRTNSFSLSPLHSNTKINGAHHSTVQGPSST 323
L+QL + + + H S+SL P S + + A + P
Sbjct: 3346 LH--RLRQLLEQPESDSRINGVSPWASPQHSALSYSLDPDASGPQFHQAAGEDLLAPPHD 3403
Query: 324 KSTSSV-------STFSKAAPSVPSKP 343
ST STF P+VPS+P
Sbjct: 3404 TSTDLTEVMEQIHSTFPSCCPNVPSRP 3430
>gi|7657218 bromodomain-containing protein 4 isoform short [Homo
sapiens]
Length = 722
Score = 34.7 bits (78), Expect = 0.59
Identities = 41/166 (24%), Positives = 73/166 (43%), Gaps = 23/166 (13%)
Query: 967 DKKKEPVNGCNTGILPQPVGTVLLQIPEPQESNSDAGINLIALPAFSQVDPEVFAALPAE 1026
D+ +EPV ++ +P P T ++ P +S+SD+ + + S+ E A AE
Sbjct: 459 DEPEEPVVAVSSPAVPPP--TKVVAPPSSSDSSSDSSSDSDSSTDDSE---EERAQRLAE 513
Query: 1027 LQRELKAAYDQ---RQRQGENSTHQQSASASVPKNPLLHLKAAVKEKKRNKKKKTIGSPK 1083
LQ +LKA ++Q + +N ++ K K V+E K++K K+ PK
Sbjct: 514 LQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEP--PPK 571
Query: 1084 RIQSPLNNKLLNSPAKTLPGACGSPQKLIDGFLKHEGPPAEKPLEE 1129
+ + NN ++ +K P +K + PP + EE
Sbjct: 572 KTKK--NNSSNSNVSKKEPAP-----------MKSKPPPTYESEEE 604
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 34.7 bits (78), Expect = 0.59
Identities = 41/166 (24%), Positives = 73/166 (43%), Gaps = 23/166 (13%)
Query: 967 DKKKEPVNGCNTGILPQPVGTVLLQIPEPQESNSDAGINLIALPAFSQVDPEVFAALPAE 1026
D+ +EPV ++ +P P T ++ P +S+SD+ + + S+ E A AE
Sbjct: 459 DEPEEPVVAVSSPAVPPP--TKVVAPPSSSDSSSDSSSDSDSSTDDSE---EERAQRLAE 513
Query: 1027 LQRELKAAYDQ---RQRQGENSTHQQSASASVPKNPLLHLKAAVKEKKRNKKKKTIGSPK 1083
LQ +LKA ++Q + +N ++ K K V+E K++K K+ PK
Sbjct: 514 LQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEP--PPK 571
Query: 1084 RIQSPLNNKLLNSPAKTLPGACGSPQKLIDGFLKHEGPPAEKPLEE 1129
+ + NN ++ +K P +K + PP + EE
Sbjct: 572 KTKK--NNSSNSNVSKKEPAP-----------MKSKPPPTYESEEE 604
>gi|239757877 PREDICTED: FERM and PDZ domain containing 3 [Homo
sapiens]
Length = 1662
Score = 34.3 bits (77), Expect = 0.76
Identities = 33/118 (27%), Positives = 49/118 (41%), Gaps = 15/118 (12%)
Query: 284 RNTDALRNPHRTNSFSLSPLHS-NTKINGAHHSTVQGPSSTKSTSSV----STFSKAAPS 338
R LR+ + S P T +NGAH ST +GP+ KS+ + FS P+
Sbjct: 1053 RGQSPLRSQAASRQVSTMPSRKLETTLNGAH-STSEGPAKPKSSRGPFRLRNLFSATFPT 1111
Query: 339 VPSKPSDCNFISNFYSHSRLHHISMWKCELTEFVNTLQRQSNGIFPGREKLKKMKTGR 396
K +D ++L + ++ E E L+ S G PG E L+ GR
Sbjct: 1112 RQKKETD-------ERQAQLQKVKQYELEFLE--ELLKPPSQGELPGTEYLQPPAPGR 1160
>gi|89060961 PREDICTED: FERM and PDZ domain containing 3 [Homo
sapiens]
Length = 1810
Score = 34.3 bits (77), Expect = 0.76
Identities = 33/118 (27%), Positives = 49/118 (41%), Gaps = 15/118 (12%)
Query: 284 RNTDALRNPHRTNSFSLSPLHS-NTKINGAHHSTVQGPSSTKSTSSV----STFSKAAPS 338
R LR+ + S P T +NGAH ST +GP+ KS+ + FS P+
Sbjct: 1201 RGQSPLRSQAASRQVSTMPSRKLETTLNGAH-STSEGPAKPKSSRGPFRLRNLFSATFPT 1259
Query: 339 VPSKPSDCNFISNFYSHSRLHHISMWKCELTEFVNTLQRQSNGIFPGREKLKKMKTGR 396
K +D ++L + ++ E E L+ S G PG E L+ GR
Sbjct: 1260 RQKKETD-------ERQAQLQKVKQYELEFLE--ELLKPPSQGELPGTEYLQPPAPGR 1308
>gi|89059963 PREDICTED: FERM and PDZ domain containing 3 [Homo
sapiens]
Length = 1810
Score = 34.3 bits (77), Expect = 0.76
Identities = 33/118 (27%), Positives = 49/118 (41%), Gaps = 15/118 (12%)
Query: 284 RNTDALRNPHRTNSFSLSPLHS-NTKINGAHHSTVQGPSSTKSTSSV----STFSKAAPS 338
R LR+ + S P T +NGAH ST +GP+ KS+ + FS P+
Sbjct: 1201 RGQSPLRSQAASRQVSTMPSRKLETTLNGAH-STSEGPAKPKSSRGPFRLRNLFSATFPT 1259
Query: 339 VPSKPSDCNFISNFYSHSRLHHISMWKCELTEFVNTLQRQSNGIFPGREKLKKMKTGR 396
K +D ++L + ++ E E L+ S G PG E L+ GR
Sbjct: 1260 RQKKETD-------ERQAQLQKVKQYELEFLE--ELLKPPSQGELPGTEYLQPPAPGR 1308
>gi|83367077 mucin 16 [Homo sapiens]
Length = 14507
Score = 33.9 bits (76), Expect = 1.00
Identities = 30/111 (27%), Positives = 47/111 (42%), Gaps = 6/111 (5%)
Query: 232 SNGALKTQDCLVPMVNSVASRLSPAFSQEEDKAEKSSTDFRDCTLQQLQQSTRNTDALRN 291
S+ + Q P VNSVA SP +S+ + +L+ L + +A+ +
Sbjct: 1991 SSEKVSVQTQSTPYVNSVAVSASPTHENSVSSGSSTSSPYSSASLESLDSTISRRNAITS 2050
Query: 292 PHRTNSFSLS----PLHSNTKINGAHHSTVQGPSSTKSTSSVSTFSKAAPS 338
+ SL P S ++ + HS V PSST T+ FS A+ S
Sbjct: 2051 WLWDLTTSLPTTTWPSTSLSEALSSGHSGVSNPSST--TTEFPLFSAASTS 2099
>gi|239754668 PREDICTED: mucin 12 [Homo sapiens]
Length = 1952
Score = 33.9 bits (76), Expect = 1.00
Identities = 33/128 (25%), Positives = 48/128 (37%), Gaps = 16/128 (12%)
Query: 248 SVASRLSPAFSQEEDKAEKSSTDFRDCTLQQLQQSTRNTDALRNPHRTNSFSL----SPL 303
S + LSP + +S+T S T R P T + L +P+
Sbjct: 266 STDTTLSPGTTTPSSLGPESTT---------FHSSPGYTKTTRLPDNTTTSGLLEASTPV 316
Query: 304 HSNTKINGAHHSTVQGPSSTKSTSSVSTFSKAAPSVPSKPSDCNFISNFYSHSRLHHISM 363
HS+T G+ H+T+ SST +TF S + P+ S F S +H S
Sbjct: 317 HSST---GSPHTTLSPASSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSP 373
Query: 364 WKCELTEF 371
T F
Sbjct: 374 SSTPTTHF 381
>gi|239749217 PREDICTED: similar to Mucin-12, partial [Homo sapiens]
Length = 861
Score = 33.9 bits (76), Expect = 1.00
Identities = 33/128 (25%), Positives = 48/128 (37%), Gaps = 16/128 (12%)
Query: 248 SVASRLSPAFSQEEDKAEKSSTDFRDCTLQQLQQSTRNTDALRNPHRTNSFSL----SPL 303
S + LSP + +S+T S T R P T + L +P+
Sbjct: 201 STDTTLSPGTTTPSSLGPESTT---------FHSSPGYTKTTRLPDNTTTSGLLEASTPV 251
Query: 304 HSNTKINGAHHSTVQGPSSTKSTSSVSTFSKAAPSVPSKPSDCNFISNFYSHSRLHHISM 363
HS+T G+ H+T+ SST +TF S + P+ S F S +H S
Sbjct: 252 HSST---GSPHTTLSPSSSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSP 308
Query: 364 WKCELTEF 371
T F
Sbjct: 309 SSTPTTHF 316
>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
Length = 5478
Score = 33.9 bits (76), Expect = 1.00
Identities = 33/128 (25%), Positives = 48/128 (37%), Gaps = 16/128 (12%)
Query: 248 SVASRLSPAFSQEEDKAEKSSTDFRDCTLQQLQQSTRNTDALRNPHRTNSFSL----SPL 303
S + LSP + +S+T S T R P T + L +P+
Sbjct: 345 STDTTLSPGTTTPSSLGPESTT---------FHSSPGYTKTTRLPDNTTTSGLLEASTPV 395
Query: 304 HSNTKINGAHHSTVQGPSSTKSTSSVSTFSKAAPSVPSKPSDCNFISNFYSHSRLHHISM 363
HS+T G+ H+T+ SST +TF S + P+ S F S +H S
Sbjct: 396 HSST---GSPHTTLSPSSSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSP 452
Query: 364 WKCELTEF 371
T F
Sbjct: 453 SSTPTTHF 460
>gi|239745855 PREDICTED: hypothetical protein XP_002343606 [Homo
sapiens]
Length = 870
Score = 33.5 bits (75), Expect = 1.3
Identities = 38/170 (22%), Positives = 62/170 (36%), Gaps = 14/170 (8%)
Query: 898 PTSPDTNKAESSGKWNGLHTPVSVQSRLNLSIEVPSPSQ---LDQSVLEALPPDLREQV- 953
P P + E TP +++ P Q LD + PPD++ +
Sbjct: 363 PVQPSESSREVESSLTQQETPGQPPEHHEVTVSPPGHHQTHHLDSPSVSVKPPDVQLTIA 422
Query: 954 -EQVCAVQQAESHGDKKKEPVNGCNTGILPQPV---GTVLLQIPEPQESNSDAGINLIAL 1009
E V + H + ++G + P + G LL ES+ +AG +
Sbjct: 423 AEPSAEVGTSLVHQEATAR-LSGSGNDVEPPAIQHGGPPLLP-----ESSEEAGPLAVQQ 476
Query: 1010 PAFSQVDPEVFAALPAELQRELKAAYDQRQRQGENSTHQQSASASVPKNP 1059
Q + P+ Q+E A + Q +GE+S Q A A P+ P
Sbjct: 477 ETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFP 526
>gi|151301154 mucin 6, gastric [Homo sapiens]
Length = 2439
Score = 33.1 bits (74), Expect = 1.7
Identities = 29/127 (22%), Positives = 52/127 (40%), Gaps = 14/127 (11%)
Query: 218 PRGSTAIFNGHTPSSNGALKTQDCLVPMVNSVASRLSPAFSQEEDKAEKSSTDFRDCTLQ 277
PR +TA+ TP + L P ++ P +Q +A S+ T
Sbjct: 1272 PRPTTAV----TPQATSGLP------PTATLRSTATKPTVTQATTRATASTAS--PATTS 1319
Query: 278 QLQQSTRNTDALRNPHRTNSFSLSPLHSNTKINGAHHSTVQGPSSTKSTSSVSTFSKAAP 337
Q +TR T L P + + P +N ++ G + GP T ++++ T + P
Sbjct: 1320 TAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTGPTTPQ--P 1377
Query: 338 SVPSKPS 344
P++P+
Sbjct: 1378 GQPTRPT 1384
Score = 32.3 bits (72), Expect = 2.9
Identities = 28/129 (21%), Positives = 57/129 (44%), Gaps = 10/129 (7%)
Query: 230 PSSNGALKTQDCLVPMVNSVASRLSPAFSQEEDKAEKSSTDFRDCTLQQLQQSTRNTDAL 289
P ++ + + + ++S +P + + + S + T+ S+ ++
Sbjct: 2095 PQNSSSRPPSSPITTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQT 2154
Query: 290 RNPH--RTNSFSLSPLHSNTKINGAHHSTVQGPSSTKSTSSVSTFSKAAPSVPSKPSDCN 347
+P ++SF +P+HS T +G+H S S+ +T+SVS A+P PS P+
Sbjct: 2155 SSPSVGTSSSFVSAPVHSTTLSSGSHSSL----STHPTTASVS----ASPLFPSSPAAST 2206
Query: 348 FISNFYSHS 356
I H+
Sbjct: 2207 TIRATLPHT 2215
>gi|154091020 leucine-rich repeats and calponin homology (CH) domain
containing 2 [Homo sapiens]
Length = 765
Score = 32.7 bits (73), Expect = 2.2
Identities = 29/134 (21%), Positives = 55/134 (41%), Gaps = 11/134 (8%)
Query: 164 LNNRVNHIVKKIETENEVKVNGMNSWNEEDENNDFSFVDLEQTSPGRKQNGIPHPRGSTA 223
L+++V+ ++ + N+ + G + +++D+ + FVD + G H +
Sbjct: 371 LHSQVSESNREQTSRNDSHIIGSKTDSQKDQEV-YDFVDPNTEDVAVPEQGNAHIGSFVS 429
Query: 224 IFNGHTPSSNGALKTQDCLVPMVNSVASRLSPAFSQEEDKAEKSSTDFRDCTLQQLQQST 283
F G S + K ++ + + ++EED K TD R Q LQQ
Sbjct: 430 FFKGKEKCSEKSRKNEE----LGDEKRLEKEQLLAEEEDDDLKEVTDLRKIAAQLLQQEQ 485
Query: 284 RN------TDALRN 291
+N T +RN
Sbjct: 486 KNRILNHSTSVMRN 499
>gi|161016767 mucin 21 [Homo sapiens]
Length = 566
Score = 32.7 bits (73), Expect = 2.2
Identities = 32/147 (21%), Positives = 63/147 (42%), Gaps = 4/147 (2%)
Query: 195 NNDFSFVDLEQTSPGRKQNGIPHPRGSTAIFNGHTPSSNGALKTQDCLVPMVNSVASRLS 254
N++ S ++ ++ P STA + + +S+GA + +S AS +
Sbjct: 107 NSESSTTSSGASTATNSESSTPSSGASTATNSDSSTTSSGASTATNSDSSTTSSEASTAT 166
Query: 255 PAFSQEEDKAEKSSTDFRDCTLQQLQQSTRNTDALRNPHRTNSFSLSPLHSNTKINGAHH 314
+ S ++T+ T+ + N+++ ++ + S S T NGA
Sbjct: 167 NSESSTTSSGASTATNSESSTVSSRASTATNSESSTTSSGASTATNS--ESRTTSNGAGT 224
Query: 315 STVQGPSSTKSTSSVSTFSKAAPSVPS 341
+T S+T S +S +T S++ S PS
Sbjct: 225 ATNSESSTTSSGASTATNSES--STPS 249
Score = 32.0 bits (71), Expect = 3.8
Identities = 37/150 (24%), Positives = 62/150 (41%), Gaps = 11/150 (7%)
Query: 195 NNDFSFVDLEQTSPGRKQNGIPHPRGSTAIFNGHTPSSNGALKTQDCLVPMVNSVASRLS 254
N++ S V ++ ++ P +TA + + +S+GA NS +S S
Sbjct: 272 NSESSTVSSGISTVTNSESSTPSSGANTATNSESSTTSSGANTA-------TNSDSSTTS 324
Query: 255 PAFSQEEDKAEKSSTDFRDCTLQQLQQSTRNTDALRNPHRTNSFSLSPLHSNTKINGAHH 314
S + +E S+T T + ST ++ A TNS S + + +
Sbjct: 325 SGASTATN-SESSTTSSGASTATNSESSTTSSGAST---ATNSGSSTTSSGTSTATNSES 380
Query: 315 STVQGPSSTKSTSSVSTFSKAAPSVPSKPS 344
STV +ST +TS ST S A + + S
Sbjct: 381 STVSSGASTATTSESSTTSSGASTATNSES 410
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.130 0.377
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 49,877,088
Number of Sequences: 37866
Number of extensions: 2401448
Number of successful extensions: 6400
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 53
Number of HSP's that attempted gapping in prelim test: 6277
Number of HSP's gapped (non-prelim): 180
length of query: 1250
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1136
effective length of database: 13,930,794
effective search space: 15825381984
effective search space used: 15825381984
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.