Guide to the Human Genome
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Search of human proteins with 84043967

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|84043967 REV1-like isoform 2 [Homo sapiens]
         (1250 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|84043967 REV1-like isoform 2 [Homo sapiens]                       2507   0.0  
gi|7706681 REV1-like isoform 1 [Homo sapiens]                        2503   0.0  
gi|154350220 DNA polymerase iota [Homo sapiens]                        99   3e-20
gi|7705344 DNA-directed DNA polymerase kappa [Homo sapiens]            96   2e-19
gi|5729982 DNA-directed DNA polymerase eta [Homo sapiens]              69   2e-11
gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens]       40   0.011
gi|195972857 Rho/Rac guanine nucleotide exchange factor 18 isofo...    38   0.053
gi|41327769 Rho/Rac guanine nucleotide exchange factor 18 isofor...    38   0.053
gi|236462242 potassium voltage-gated channel, KQT-like subfamily...    38   0.069
gi|236462079 potassium voltage-gated channel, KQT-like subfamily...    38   0.069
gi|236461942 potassium voltage-gated channel, KQT-like subfamily...    38   0.069
gi|236461719 potassium voltage-gated channel, KQT-like subfamily...    38   0.069
gi|28373065 potassium voltage-gated channel, KQT-like subfamily,...    38   0.069
gi|194440660 topoisomerase (DNA) II binding protein 1 [Homo sapi...    38   0.069
gi|150170670 piccolo isoform 2 [Homo sapiens]                          35   0.34 
gi|150378539 piccolo isoform 1 [Homo sapiens]                          35   0.34 
gi|110611228 utrophin [Homo sapiens]                                   35   0.45 
gi|7657218 bromodomain-containing protein 4 isoform short [Homo ...    35   0.59 
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ...    35   0.59 
gi|239757877 PREDICTED: FERM and PDZ domain containing 3 [Homo s...    34   0.76 
gi|89060961 PREDICTED: FERM and PDZ domain containing 3 [Homo sa...    34   0.76 
gi|89059963 PREDICTED: FERM and PDZ domain containing 3 [Homo sa...    34   0.76 
gi|83367077 mucin 16 [Homo sapiens]                                    34   1.00 
gi|239754668 PREDICTED: mucin 12 [Homo sapiens]                        34   1.00 
gi|239749217 PREDICTED: similar to Mucin-12, partial [Homo sapiens]    34   1.00 
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                        34   1.00 
gi|239745855 PREDICTED: hypothetical protein XP_002343606 [Homo ...    33   1.3  
gi|151301154 mucin 6, gastric [Homo sapiens]                           33   1.7  
gi|154091020 leucine-rich repeats and calponin homology (CH) dom...    33   2.2  
gi|161016767 mucin 21 [Homo sapiens]                                   33   2.2  

>gi|84043967 REV1-like isoform 2 [Homo sapiens]
          Length = 1250

 Score = 2507 bits (6498), Expect = 0.0
 Identities = 1250/1250 (100%), Positives = 1250/1250 (100%)

Query: 1    MRRGGWRKRAENDGWETWGGYMAAKVQKLEEQFRSDAAMQKDGTSSTIFSGVAIYVNGYT 60
            MRRGGWRKRAENDGWETWGGYMAAKVQKLEEQFRSDAAMQKDGTSSTIFSGVAIYVNGYT
Sbjct: 1    MRRGGWRKRAENDGWETWGGYMAAKVQKLEEQFRSDAAMQKDGTSSTIFSGVAIYVNGYT 60

Query: 61   DPSAEELRKLMMLHGGQYHVYYSRSKTTHIIATNLPNAKIKELKGEKVIRPEWIVESIKA 120
            DPSAEELRKLMMLHGGQYHVYYSRSKTTHIIATNLPNAKIKELKGEKVIRPEWIVESIKA
Sbjct: 61   DPSAEELRKLMMLHGGQYHVYYSRSKTTHIIATNLPNAKIKELKGEKVIRPEWIVESIKA 120

Query: 121  GRLLSYIPYQLYTKQSSVQKGLSFNPVCRPEDPLPGPSNIAKQLNNRVNHIVKKIETENE 180
            GRLLSYIPYQLYTKQSSVQKGLSFNPVCRPEDPLPGPSNIAKQLNNRVNHIVKKIETENE
Sbjct: 121  GRLLSYIPYQLYTKQSSVQKGLSFNPVCRPEDPLPGPSNIAKQLNNRVNHIVKKIETENE 180

Query: 181  VKVNGMNSWNEEDENNDFSFVDLEQTSPGRKQNGIPHPRGSTAIFNGHTPSSNGALKTQD 240
            VKVNGMNSWNEEDENNDFSFVDLEQTSPGRKQNGIPHPRGSTAIFNGHTPSSNGALKTQD
Sbjct: 181  VKVNGMNSWNEEDENNDFSFVDLEQTSPGRKQNGIPHPRGSTAIFNGHTPSSNGALKTQD 240

Query: 241  CLVPMVNSVASRLSPAFSQEEDKAEKSSTDFRDCTLQQLQQSTRNTDALRNPHRTNSFSL 300
            CLVPMVNSVASRLSPAFSQEEDKAEKSSTDFRDCTLQQLQQSTRNTDALRNPHRTNSFSL
Sbjct: 241  CLVPMVNSVASRLSPAFSQEEDKAEKSSTDFRDCTLQQLQQSTRNTDALRNPHRTNSFSL 300

Query: 301  SPLHSNTKINGAHHSTVQGPSSTKSTSSVSTFSKAAPSVPSKPSDCNFISNFYSHSRLHH 360
            SPLHSNTKINGAHHSTVQGPSSTKSTSSVSTFSKAAPSVPSKPSDCNFISNFYSHSRLHH
Sbjct: 301  SPLHSNTKINGAHHSTVQGPSSTKSTSSVSTFSKAAPSVPSKPSDCNFISNFYSHSRLHH 360

Query: 361  ISMWKCELTEFVNTLQRQSNGIFPGREKLKKMKTGRSALVVTDTGDMSVLNSPRHQSCIM 420
            ISMWKCELTEFVNTLQRQSNGIFPGREKLKKMKTGRSALVVTDTGDMSVLNSPRHQSCIM
Sbjct: 361  ISMWKCELTEFVNTLQRQSNGIFPGREKLKKMKTGRSALVVTDTGDMSVLNSPRHQSCIM 420

Query: 421  HVDMDCFFVSVGIRNRPDLKGKPVAVTSNRGTGRAPLRPGANPQLEWQYYQNKILKGKAD 480
            HVDMDCFFVSVGIRNRPDLKGKPVAVTSNRGTGRAPLRPGANPQLEWQYYQNKILKGKAD
Sbjct: 421  HVDMDCFFVSVGIRNRPDLKGKPVAVTSNRGTGRAPLRPGANPQLEWQYYQNKILKGKAD 480

Query: 481  IPDSSLWENPDSAQANGIDSVLSRAEIASCSYEARQLGIKNGMFFGHAKQLCPNLQAVPY 540
            IPDSSLWENPDSAQANGIDSVLSRAEIASCSYEARQLGIKNGMFFGHAKQLCPNLQAVPY
Sbjct: 481  IPDSSLWENPDSAQANGIDSVLSRAEIASCSYEARQLGIKNGMFFGHAKQLCPNLQAVPY 540

Query: 541  DFHAYKEVAQTLYETLASYTHNIEAVSCDEALVDITEILAETKLTPDEFANAVRMEIKDQ 600
            DFHAYKEVAQTLYETLASYTHNIEAVSCDEALVDITEILAETKLTPDEFANAVRMEIKDQ
Sbjct: 541  DFHAYKEVAQTLYETLASYTHNIEAVSCDEALVDITEILAETKLTPDEFANAVRMEIKDQ 600

Query: 601  TKCAASVGIGSNILLARMATRKAKPDGQYHLKPEEVDDFIRGQLVTNLPGVGHSMESKLA 660
            TKCAASVGIGSNILLARMATRKAKPDGQYHLKPEEVDDFIRGQLVTNLPGVGHSMESKLA
Sbjct: 601  TKCAASVGIGSNILLARMATRKAKPDGQYHLKPEEVDDFIRGQLVTNLPGVGHSMESKLA 660

Query: 661  SLGIKTCGDLQYMTMAKLQKEFGPKTGQMLYRFCRGLDDRPVRTEKERKSVSAEINYGIR 720
            SLGIKTCGDLQYMTMAKLQKEFGPKTGQMLYRFCRGLDDRPVRTEKERKSVSAEINYGIR
Sbjct: 661  SLGIKTCGDLQYMTMAKLQKEFGPKTGQMLYRFCRGLDDRPVRTEKERKSVSAEINYGIR 720

Query: 721  FTQPKEAEAFLLSLSEEIQRRLEATGMKGKRLTLKIMVRKPGAPVETAKFGGHGICDNIA 780
            FTQPKEAEAFLLSLSEEIQRRLEATGMKGKRLTLKIMVRKPGAPVETAKFGGHGICDNIA
Sbjct: 721  FTQPKEAEAFLLSLSEEIQRRLEATGMKGKRLTLKIMVRKPGAPVETAKFGGHGICDNIA 780

Query: 781  RTVTLDQATDNAKIIGKAMLNMFHTMKLNISDMRGVGIHVNQLVPTNLNPSTCPSRPSVQ 840
            RTVTLDQATDNAKIIGKAMLNMFHTMKLNISDMRGVGIHVNQLVPTNLNPSTCPSRPSVQ
Sbjct: 781  RTVTLDQATDNAKIIGKAMLNMFHTMKLNISDMRGVGIHVNQLVPTNLNPSTCPSRPSVQ 840

Query: 841  SSHFPSGSYSVRDVFQVQKAKKSTEEEHKEVFRAAVDLEISSASRTCTFLPPFPAHLPTS 900
            SSHFPSGSYSVRDVFQVQKAKKSTEEEHKEVFRAAVDLEISSASRTCTFLPPFPAHLPTS
Sbjct: 841  SSHFPSGSYSVRDVFQVQKAKKSTEEEHKEVFRAAVDLEISSASRTCTFLPPFPAHLPTS 900

Query: 901  PDTNKAESSGKWNGLHTPVSVQSRLNLSIEVPSPSQLDQSVLEALPPDLREQVEQVCAVQ 960
            PDTNKAESSGKWNGLHTPVSVQSRLNLSIEVPSPSQLDQSVLEALPPDLREQVEQVCAVQ
Sbjct: 901  PDTNKAESSGKWNGLHTPVSVQSRLNLSIEVPSPSQLDQSVLEALPPDLREQVEQVCAVQ 960

Query: 961  QAESHGDKKKEPVNGCNTGILPQPVGTVLLQIPEPQESNSDAGINLIALPAFSQVDPEVF 1020
            QAESHGDKKKEPVNGCNTGILPQPVGTVLLQIPEPQESNSDAGINLIALPAFSQVDPEVF
Sbjct: 961  QAESHGDKKKEPVNGCNTGILPQPVGTVLLQIPEPQESNSDAGINLIALPAFSQVDPEVF 1020

Query: 1021 AALPAELQRELKAAYDQRQRQGENSTHQQSASASVPKNPLLHLKAAVKEKKRNKKKKTIG 1080
            AALPAELQRELKAAYDQRQRQGENSTHQQSASASVPKNPLLHLKAAVKEKKRNKKKKTIG
Sbjct: 1021 AALPAELQRELKAAYDQRQRQGENSTHQQSASASVPKNPLLHLKAAVKEKKRNKKKKTIG 1080

Query: 1081 SPKRIQSPLNNKLLNSPAKTLPGACGSPQKLIDGFLKHEGPPAEKPLEELSASTSGVPGL 1140
            SPKRIQSPLNNKLLNSPAKTLPGACGSPQKLIDGFLKHEGPPAEKPLEELSASTSGVPGL
Sbjct: 1081 SPKRIQSPLNNKLLNSPAKTLPGACGSPQKLIDGFLKHEGPPAEKPLEELSASTSGVPGL 1140

Query: 1141 SSLQSDPAGCVRPPAPNLAGAVEFNDVKTLLREWITTISDPMEEDILQVVKYCTDLIEEK 1200
            SSLQSDPAGCVRPPAPNLAGAVEFNDVKTLLREWITTISDPMEEDILQVVKYCTDLIEEK
Sbjct: 1141 SSLQSDPAGCVRPPAPNLAGAVEFNDVKTLLREWITTISDPMEEDILQVVKYCTDLIEEK 1200

Query: 1201 DLEKLDLVIKYMKRLMQQSVESVWNMAFDFILDNVQVVLQQTYGSTLKVT 1250
            DLEKLDLVIKYMKRLMQQSVESVWNMAFDFILDNVQVVLQQTYGSTLKVT
Sbjct: 1201 DLEKLDLVIKYMKRLMQQSVESVWNMAFDFILDNVQVVLQQTYGSTLKVT 1250


>gi|7706681 REV1-like isoform 1 [Homo sapiens]
          Length = 1251

 Score = 2503 bits (6486), Expect = 0.0
 Identities = 1250/1251 (99%), Positives = 1250/1251 (99%), Gaps = 1/1251 (0%)

Query: 1    MRRGGWRKRAENDGWETWGGYMAAKVQKLEEQFRSDAAMQKDGTSSTIFSGVAIYVNGYT 60
            MRRGGWRKRAENDGWETWGGYMAAKVQKLEEQFRSDAAMQKDGTSSTIFSGVAIYVNGYT
Sbjct: 1    MRRGGWRKRAENDGWETWGGYMAAKVQKLEEQFRSDAAMQKDGTSSTIFSGVAIYVNGYT 60

Query: 61   DPSAEELRKLMMLHGGQYHVYYSRSKTTHIIATNLPNAKIKELKGEKVIRPEWIVESIKA 120
            DPSAEELRKLMMLHGGQYHVYYSRSKTTHIIATNLPNAKIKELKGEKVIRPEWIVESIKA
Sbjct: 61   DPSAEELRKLMMLHGGQYHVYYSRSKTTHIIATNLPNAKIKELKGEKVIRPEWIVESIKA 120

Query: 121  GRLLSYIPYQLYTKQSSVQKGLSFNPVCRPEDPLPGPSNIAKQLNNRVNHIVKKIETENE 180
            GRLLSYIPYQLYTKQSSVQKGLSFNPVCRPEDPLPGPSNIAKQLNNRVNHIVKKIETENE
Sbjct: 121  GRLLSYIPYQLYTKQSSVQKGLSFNPVCRPEDPLPGPSNIAKQLNNRVNHIVKKIETENE 180

Query: 181  VKVNGMNSWNEEDENNDFSFVDLEQTSPGRKQNGIPHPRGSTAIFNGHTPSSNGALKTQD 240
            VKVNGMNSWNEEDENNDFSFVDLEQTSPGRKQNGIPHPRGSTAIFNGHTPSSNGALKTQD
Sbjct: 181  VKVNGMNSWNEEDENNDFSFVDLEQTSPGRKQNGIPHPRGSTAIFNGHTPSSNGALKTQD 240

Query: 241  CLVPMVNSVASRLSPAFSQEEDKAEKSSTDFRDCTLQQLQQSTRNTDALRNPHRTNSFSL 300
            CLVPMVNSVASRLSPAFSQEEDKAEKSSTDFRDCTLQQLQQSTRNTDALRNPHRTNSFSL
Sbjct: 241  CLVPMVNSVASRLSPAFSQEEDKAEKSSTDFRDCTLQQLQQSTRNTDALRNPHRTNSFSL 300

Query: 301  SPLHSNTKINGAHHSTVQGPSSTKSTSSVSTFSKAAPSVPSKPSDCNFISNFYSHSRLHH 360
            SPLHSNTKINGAHHSTVQGPSSTKSTSSVSTFSKAAPSVPSKPSDCNFISNFYSHSRLHH
Sbjct: 301  SPLHSNTKINGAHHSTVQGPSSTKSTSSVSTFSKAAPSVPSKPSDCNFISNFYSHSRLHH 360

Query: 361  ISMWKCELTEFVNTLQRQSNGIFPGREKLKKMKTGRSALVVTDTGDMSVLNSPRHQSCIM 420
            ISMWKCELTEFVNTLQRQSNGIFPGREKLKKMKTGRSALVVTDTGDMSVLNSPRHQSCIM
Sbjct: 361  ISMWKCELTEFVNTLQRQSNGIFPGREKLKKMKTGRSALVVTDTGDMSVLNSPRHQSCIM 420

Query: 421  HVDMDCFFVSVGIRNRPDLKGKPVAVTSNRGTGRAPLRPGANPQLEWQYYQNKILKGKA- 479
            HVDMDCFFVSVGIRNRPDLKGKPVAVTSNRGTGRAPLRPGANPQLEWQYYQNKILKGKA 
Sbjct: 421  HVDMDCFFVSVGIRNRPDLKGKPVAVTSNRGTGRAPLRPGANPQLEWQYYQNKILKGKAA 480

Query: 480  DIPDSSLWENPDSAQANGIDSVLSRAEIASCSYEARQLGIKNGMFFGHAKQLCPNLQAVP 539
            DIPDSSLWENPDSAQANGIDSVLSRAEIASCSYEARQLGIKNGMFFGHAKQLCPNLQAVP
Sbjct: 481  DIPDSSLWENPDSAQANGIDSVLSRAEIASCSYEARQLGIKNGMFFGHAKQLCPNLQAVP 540

Query: 540  YDFHAYKEVAQTLYETLASYTHNIEAVSCDEALVDITEILAETKLTPDEFANAVRMEIKD 599
            YDFHAYKEVAQTLYETLASYTHNIEAVSCDEALVDITEILAETKLTPDEFANAVRMEIKD
Sbjct: 541  YDFHAYKEVAQTLYETLASYTHNIEAVSCDEALVDITEILAETKLTPDEFANAVRMEIKD 600

Query: 600  QTKCAASVGIGSNILLARMATRKAKPDGQYHLKPEEVDDFIRGQLVTNLPGVGHSMESKL 659
            QTKCAASVGIGSNILLARMATRKAKPDGQYHLKPEEVDDFIRGQLVTNLPGVGHSMESKL
Sbjct: 601  QTKCAASVGIGSNILLARMATRKAKPDGQYHLKPEEVDDFIRGQLVTNLPGVGHSMESKL 660

Query: 660  ASLGIKTCGDLQYMTMAKLQKEFGPKTGQMLYRFCRGLDDRPVRTEKERKSVSAEINYGI 719
            ASLGIKTCGDLQYMTMAKLQKEFGPKTGQMLYRFCRGLDDRPVRTEKERKSVSAEINYGI
Sbjct: 661  ASLGIKTCGDLQYMTMAKLQKEFGPKTGQMLYRFCRGLDDRPVRTEKERKSVSAEINYGI 720

Query: 720  RFTQPKEAEAFLLSLSEEIQRRLEATGMKGKRLTLKIMVRKPGAPVETAKFGGHGICDNI 779
            RFTQPKEAEAFLLSLSEEIQRRLEATGMKGKRLTLKIMVRKPGAPVETAKFGGHGICDNI
Sbjct: 721  RFTQPKEAEAFLLSLSEEIQRRLEATGMKGKRLTLKIMVRKPGAPVETAKFGGHGICDNI 780

Query: 780  ARTVTLDQATDNAKIIGKAMLNMFHTMKLNISDMRGVGIHVNQLVPTNLNPSTCPSRPSV 839
            ARTVTLDQATDNAKIIGKAMLNMFHTMKLNISDMRGVGIHVNQLVPTNLNPSTCPSRPSV
Sbjct: 781  ARTVTLDQATDNAKIIGKAMLNMFHTMKLNISDMRGVGIHVNQLVPTNLNPSTCPSRPSV 840

Query: 840  QSSHFPSGSYSVRDVFQVQKAKKSTEEEHKEVFRAAVDLEISSASRTCTFLPPFPAHLPT 899
            QSSHFPSGSYSVRDVFQVQKAKKSTEEEHKEVFRAAVDLEISSASRTCTFLPPFPAHLPT
Sbjct: 841  QSSHFPSGSYSVRDVFQVQKAKKSTEEEHKEVFRAAVDLEISSASRTCTFLPPFPAHLPT 900

Query: 900  SPDTNKAESSGKWNGLHTPVSVQSRLNLSIEVPSPSQLDQSVLEALPPDLREQVEQVCAV 959
            SPDTNKAESSGKWNGLHTPVSVQSRLNLSIEVPSPSQLDQSVLEALPPDLREQVEQVCAV
Sbjct: 901  SPDTNKAESSGKWNGLHTPVSVQSRLNLSIEVPSPSQLDQSVLEALPPDLREQVEQVCAV 960

Query: 960  QQAESHGDKKKEPVNGCNTGILPQPVGTVLLQIPEPQESNSDAGINLIALPAFSQVDPEV 1019
            QQAESHGDKKKEPVNGCNTGILPQPVGTVLLQIPEPQESNSDAGINLIALPAFSQVDPEV
Sbjct: 961  QQAESHGDKKKEPVNGCNTGILPQPVGTVLLQIPEPQESNSDAGINLIALPAFSQVDPEV 1020

Query: 1020 FAALPAELQRELKAAYDQRQRQGENSTHQQSASASVPKNPLLHLKAAVKEKKRNKKKKTI 1079
            FAALPAELQRELKAAYDQRQRQGENSTHQQSASASVPKNPLLHLKAAVKEKKRNKKKKTI
Sbjct: 1021 FAALPAELQRELKAAYDQRQRQGENSTHQQSASASVPKNPLLHLKAAVKEKKRNKKKKTI 1080

Query: 1080 GSPKRIQSPLNNKLLNSPAKTLPGACGSPQKLIDGFLKHEGPPAEKPLEELSASTSGVPG 1139
            GSPKRIQSPLNNKLLNSPAKTLPGACGSPQKLIDGFLKHEGPPAEKPLEELSASTSGVPG
Sbjct: 1081 GSPKRIQSPLNNKLLNSPAKTLPGACGSPQKLIDGFLKHEGPPAEKPLEELSASTSGVPG 1140

Query: 1140 LSSLQSDPAGCVRPPAPNLAGAVEFNDVKTLLREWITTISDPMEEDILQVVKYCTDLIEE 1199
            LSSLQSDPAGCVRPPAPNLAGAVEFNDVKTLLREWITTISDPMEEDILQVVKYCTDLIEE
Sbjct: 1141 LSSLQSDPAGCVRPPAPNLAGAVEFNDVKTLLREWITTISDPMEEDILQVVKYCTDLIEE 1200

Query: 1200 KDLEKLDLVIKYMKRLMQQSVESVWNMAFDFILDNVQVVLQQTYGSTLKVT 1250
            KDLEKLDLVIKYMKRLMQQSVESVWNMAFDFILDNVQVVLQQTYGSTLKVT
Sbjct: 1201 KDLEKLDLVIKYMKRLMQQSVESVWNMAFDFILDNVQVVLQQTYGSTLKVT 1251


>gi|154350220 DNA polymerase iota [Homo sapiens]
          Length = 740

 Score = 98.6 bits (244), Expect = 3e-20
 Identities = 97/388 (25%), Positives = 158/388 (40%), Gaps = 94/388 (24%)

Query: 409 VLNSPRHQS-CIMHVDMDCFFVSVGIRNRPDLKGKPVAVTSNRGTGRAPLRPGANPQLEW 467
           VL +P   S  I+HVD+DCF+  V + + P+LK KP+ V                     
Sbjct: 44  VLPTPNASSRVIVHVDLDCFYAQVEMISNPELKDKPLGV--------------------- 82

Query: 468 QYYQNKILKGKADIPDSSLWENPDSAQANGIDSVLSRAEIASCSYEARQLGIKNGMFFGH 527
              Q K L                               + +C+YEAR+LG+K  M    
Sbjct: 83  ---QQKYL-------------------------------VVTCNYEARKLGVKKLMNVRD 108

Query: 528 AKQLCPNLQAVP-YDFHAYKEVAQTLYETLASYTHNIEAVSCDEALVDITEILAET--KL 584
           AK+ CP L  V   D   Y+E++  + E L  ++  +E +  DE  VD+TE++ +   +L
Sbjct: 109 AKEKCPQLVLVNGEDLTRYREMSYKVTELLEEFSPVVERLGFDENFVDLTEMVEKRLQQL 168

Query: 585 TPDEF-------------------------------ANAVRMEIKDQTKCAASVGIGSNI 613
             DE                                A  +R  + +Q       G+ SN 
Sbjct: 169 QSDELSAVTVSGHVYNNQSINLLDVLHIRLLVGSQIAAEMREAMYNQLGLTGCAGVASNK 228

Query: 614 LLARMATRKAKPDGQYHLKPEEVDDFIRG-QLVTNLPGVGHSMESKLASLGIKTCGDLQY 672
           LLA++ +   KP+ Q  L PE     I     +  +PG+G+     L +LGI +  DLQ 
Sbjct: 229 LLAKLVSGVFKPNQQTVLLPESCQHLIHSLNHIKEIPGIGYKTAKCLEALGINSVRDLQT 288

Query: 673 MTMAKLQKEFGPKTGQMLYRFCRGLDDRPVRTEKERKSVSAEINYGIRFTQPKEAEAFLL 732
            +   L+KE G    Q + +   G D+ PV      +S S E ++  + +   EA+  + 
Sbjct: 289 FSPKILEKELGISVAQRIQKLSFGEDNSPVILSGPPQSFSEEDSFK-KCSSEVEAKNKIE 347

Query: 733 SLSEEIQRRLEATGMKGKRLTLKIMVRK 760
            L   +  R+   G K    T+++++R+
Sbjct: 348 ELLASLLNRVCQDGRKPH--TVRLIIRR 373


>gi|7705344 DNA-directed DNA polymerase kappa [Homo sapiens]
          Length = 870

 Score = 95.9 bits (237), Expect = 2e-19
 Identities = 101/394 (25%), Positives = 170/394 (43%), Gaps = 46/394 (11%)

Query: 396 RSALVVTDTGDMSVLNSPRHQSCIMHVDMDCFFVSVGIRNRPDLKGKPVAV-------TS 448
           R A +  D   M +  S    + I+H+DMD F+ +V +R+ P+LK KP+AV       TS
Sbjct: 80  RKAQLQVDRFAMELEQSRNLSNTIVHIDMDAFYAAVEMRDNPELKDKPIAVGSMSMLSTS 139

Query: 449 NRGTGRAPLR---PG-----ANPQL--------EWQYYQNKILKGKADIPDSSLWENPDS 492
           N    R  +R   PG       PQL        +++    ++ +  AD   + +  + D 
Sbjct: 140 NYHARRFGVRAAMPGFIAKRLCPQLIIVPPNFDKYRAVSKEVKEILADYDPNFMAMSLDE 199

Query: 493 AQANGIDSVLSRAEIASCSYEARQLGIKNGMFFGHAKQLCPNLQAVPYDFHAYKEVAQTL 552
           A  N    +  R        + R+  IK G    +     P  +      H  + ++  L
Sbjct: 200 AYLNITKHLEERQNWPE---DKRRYFIKMGSSVENDN---PGKEVNKLSEHE-RSISPLL 252

Query: 553 YETLAS--------YTHNIEAVSCDEALVDITEILAETKLTPDEFANAVRMEIKDQTKCA 604
           +E   S        +  N E  +  + L +   ++  T  +  E    +R  I+ +T   
Sbjct: 253 FEESPSDVQPPGDPFQVNFEEQNNPQILQN--SVVFGT--SAQEVVKEIRFRIEQKTTLT 308

Query: 605 ASVGIGSNILLARMATRKAKPDGQYHLKP--EEVDDFIRGQLVTNLPGVGHSMESKLASL 662
           AS GI  N +LA++ + K KP+GQY + P  + V DFI+   +  + G+G   E  L +L
Sbjct: 309 ASAGIAPNTMLAKVCSDKNKPNGQYQILPNRQAVMDFIKDLPIRKVSGIGKVTEKMLKAL 368

Query: 663 GIKTCGDLQYMTMAKLQKEFGPKTGQMLYRFCRGLDDRPVRTEKERKSVSAEINYGIRFT 722
           GI TC +L Y   A L   F   +         GL    +  + ERKS+S E  +     
Sbjct: 369 GIITCTEL-YQQRALLSLLFSETSWHYFLHISLGLGSTHLTRDGERKSMSVERTFS-EIN 426

Query: 723 QPKEAEAFLLSLSEEIQRRLEATGMKGKRLTLKI 756
           + +E  +    L  E+ + L+   +KG+ +T+K+
Sbjct: 427 KAEEQYSLCQELCSELAQDLQKERLKGRTVTIKL 460


>gi|5729982 DNA-directed DNA polymerase eta [Homo sapiens]
          Length = 713

 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 45/169 (26%), Positives = 81/169 (47%), Gaps = 3/169 (1%)

Query: 593 VRMEIKDQTKCAASVGIGSNILLARMATRKAKPDGQYHLKPEEVDDFIRGQLVTNLPGVG 652
           +R  I+ +T    S GI  N +LA++A    KP+ Q  +    V        +  +  +G
Sbjct: 200 MRAAIERETGFQCSAGISHNKVLAKLACGLNKPNRQTLVSHGSVPQLFSQMPIRKIRSLG 259

Query: 653 HSM-ESKLASLGIKTCGDLQYMTMAKLQKEFGPKTGQMLYRFCRGLDDRPVRTEKERKSV 711
             +  S +  LGI+  G+L   T ++LQ  FG K G  LY  CRG++  PV+  +  K++
Sbjct: 260 GKLGASVIEILGIEYMGELTQFTESQLQSHFGEKNGSWLYAMCRGIEHDPVKPRQLPKTI 319

Query: 712 SAEINY--GIRFTQPKEAEAFLLSLSEEIQRRLEATGMKGKRLTLKIMV 758
               N+         ++ + +LL L++E++ RL        R+  +++V
Sbjct: 320 GCSKNFPGKTALATREQVQWWLLQLAQELEERLTKDRNDNDRVATQLVV 368



 Score = 51.2 bits (121), Expect = 6e-06
 Identities = 47/167 (28%), Positives = 62/167 (37%), Gaps = 58/167 (34%)

Query: 422 VDMDCFFVSVGIRNRPDLKGKPVAVTSNRGTGRAPLRPGANPQLEWQYYQNKILKGKADI 481
           VDMDCFFV V  R  P L+ KP AV                        Q K  KG    
Sbjct: 12  VDMDCFFVQVEQRQNPHLRNKPCAVV-----------------------QYKSWKGGG-- 46

Query: 482 PDSSLWENPDSAQANGIDSVLSRAEIASCSYEARQLGIKNGMFFGHAKQLCPNLQAVPY- 540
                                    I + SYEAR  G+   M+   AK+LCP+L      
Sbjct: 47  -------------------------IIAVSYEARAFGVTRSMWADDAKKLCPDLLLAQVR 81

Query: 541 ------DFHAYKEVAQTLYETLASYTHNIEAVSCDEALVDITEILAE 581
                 +   Y+E +  + E ++ +   IE  S DEA VD+T  + E
Sbjct: 82  ESRGKANLTKYREASVEVMEIMSRFA-VIERASIDEAYVDLTSAVQE 127


>gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens]
          Length = 4374

 Score = 40.4 bits (93), Expect = 0.011
 Identities = 36/140 (25%), Positives = 59/140 (42%), Gaps = 32/140 (22%)

Query: 934  PSQLDQSVLEALPPDLREQVEQVCAVQQAESHGDKKKEPVNGCNTGILPQPVGTVLLQIP 993
            P  +D S L ALP D+R +V Q                       GI P P  T      
Sbjct: 2965 PEGVDPSFLAALPDDIRREVLQN--------------------QLGIRP-PTRTA----- 2998

Query: 994  EPQESNSDAGINLIALPAFSQVDPEVFAALPAELQRELKAAYDQRQRQGENSTHQQSASA 1053
                S + +   ++  P  ++V PE  AALP  +Q E+ A     Q++ E +   Q+AS+
Sbjct: 2999 ---PSTNSSAPAVVGNPGVTEVSPEFLAALPPAIQEEVLAQQRAEQQRRELA---QNASS 3052

Query: 1054 SVPKNPLLHLKAAVKEKKRN 1073
              P +P+  ++    + +R+
Sbjct: 3053 DTPMDPVTFIQTLPSDLRRS 3072



 Score = 31.6 bits (70), Expect = 5.0
 Identities = 41/177 (23%), Positives = 67/177 (37%), Gaps = 32/177 (18%)

Query: 894  PAHLPTSPDTNKAESSGKWNGLHTPVSVQSRLNLSIEV----PSPSQLDQSVLEALPPDL 949
            P+ L   PD  + E      G+  P       N S       P  +++    L ALPP +
Sbjct: 2970 PSFLAALPDDIRREVLQNQLGIRPPTRTAPSTNSSAPAVVGNPGVTEVSPEFLAALPPAI 3029

Query: 950  REQVEQVCAVQQAESHGDKKKEPVNGCNTGILPQPVGTVLLQIPEPQESNSDAGINLIAL 1009
            +   E+V A Q+AE    +++E     ++     PV T +  +P             +  
Sbjct: 3030 Q---EEVLAQQRAE---QQRRELAQNASSDTPMDPV-TFIQTLPSD-----------LRR 3071

Query: 1010 PAFSQVDPEVFAALPAELQRE---LKAAYDQRQRQ-------GENSTHQQSASASVP 1056
                 ++  V A +P ++  E   L+   + RQRQ       G +ST   SA    P
Sbjct: 3072 SVLEDMEDSVLAVMPPDIAAEAQALRREQEARQRQLMHERLFGHSSTSALSAILRSP 3128


>gi|195972857 Rho/Rac guanine nucleotide exchange factor 18 isoform b
            [Homo sapiens]
          Length = 1173

 Score = 38.1 bits (87), Expect = 0.053
 Identities = 55/224 (24%), Positives = 81/224 (36%), Gaps = 40/224 (17%)

Query: 944  ALPPDLREQVEQVCAVQQAESHGDK-KKEPVNGCNTGILPQPVGTVLLQIPE-------P 995
            ALPPD         A  Q  SH      E + G    +LP  VG    + PE       P
Sbjct: 964  ALPPD-------TLAEAQPPSHPPSFNGEGLEGPRVSMLPSGVGPEYAERPEVARRDSAP 1016

Query: 996  QESN---SDAGINLIALPAFSQVDPEVFAALPAELQRELKAAYDQRQRQGENSTHQQSAS 1052
             E+    SD  I L++     Q    V   +P +L    K   D+  +   +   + SAS
Sbjct: 1017 TENRLAKSDVPIQLLSATNQFQRQAAVQQQIPTKLAASTKGGKDKGGKSRGSQRWESSAS 1076

Query: 1053 ASVPKNPLLHLKAAVKEKKRNKKKKTIGSPKRIQSPLNNKLLNSPAKTLPGACGSPQKLI 1112
              + +  LL+ K   K++  ++ ++++       SP+           LPG         
Sbjct: 1077 FDLKQQLLLN-KLMGKDESTSRNRRSL-------SPI-----------LPGRHSPAPPPD 1117

Query: 1113 DGFLKHEGPPAEKPLEELSASTSGVPGLSSLQSDPAGCVRPPAP 1156
             GF     PPA+ P E  S    G    + L   PA    P  P
Sbjct: 1118 PGFPAPSPPPADSPSEGFSLKAGGT---ALLPGPPAPSPLPATP 1158


>gi|41327769 Rho/Rac guanine nucleotide exchange factor 18 isoform a
            [Homo sapiens]
          Length = 1015

 Score = 38.1 bits (87), Expect = 0.053
 Identities = 55/224 (24%), Positives = 81/224 (36%), Gaps = 40/224 (17%)

Query: 944  ALPPDLREQVEQVCAVQQAESHGDK-KKEPVNGCNTGILPQPVGTVLLQIPE-------P 995
            ALPPD         A  Q  SH      E + G    +LP  VG    + PE       P
Sbjct: 806  ALPPD-------TLAEAQPPSHPPSFNGEGLEGPRVSMLPSGVGPEYAERPEVARRDSAP 858

Query: 996  QESN---SDAGINLIALPAFSQVDPEVFAALPAELQRELKAAYDQRQRQGENSTHQQSAS 1052
             E+    SD  I L++     Q    V   +P +L    K   D+  +   +   + SAS
Sbjct: 859  TENRLAKSDVPIQLLSATNQFQRQAAVQQQIPTKLAASTKGGKDKGGKSRGSQRWESSAS 918

Query: 1053 ASVPKNPLLHLKAAVKEKKRNKKKKTIGSPKRIQSPLNNKLLNSPAKTLPGACGSPQKLI 1112
              + +  LL+ K   K++  ++ ++++       SP+           LPG         
Sbjct: 919  FDLKQQLLLN-KLMGKDESTSRNRRSL-------SPI-----------LPGRHSPAPPPD 959

Query: 1113 DGFLKHEGPPAEKPLEELSASTSGVPGLSSLQSDPAGCVRPPAP 1156
             GF     PPA+ P E  S    G    + L   PA    P  P
Sbjct: 960  PGFPAPSPPPADSPSEGFSLKAGGT---ALLPGPPAPSPLPATP 1000


>gi|236462242 potassium voltage-gated channel, KQT-like subfamily,
            member 5 isoform 5 [Homo sapiens]
          Length = 822

 Score = 37.7 bits (86), Expect = 0.069
 Identities = 52/229 (22%), Positives = 89/229 (38%), Gaps = 25/229 (10%)

Query: 813  MRGVGIHVNQLVPTNLNPSTCPSRPSVQSSHFPSGSYSVRD-VFQVQKAKKSTEEEHK-- 869
            ++ +   V+Q++      S   SR  + + H  +   S+   V +V+K  +S E +    
Sbjct: 454  IKSLQTRVDQILGKGQITSDKKSREKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCL 513

Query: 870  -EVFRAAVDLEISSASRTCTF-LPPFPAHLPT---SPDTNKAESSGKWNGLHTPVSVQSR 924
             ++++  +    +SA    +F +PPF     +   SP  +K  S    N      S  + 
Sbjct: 514  LDIYQQVLRKGSASALALASFQIPPFECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSAN 573

Query: 925  LNLSIE-VPSPSQLDQSVLEALPPDLREQVEQVCAVQQAESHGDKKKEPVNGCNTGILPQ 983
            ++  ++ + +P++       AL P +  Q  QV   Q   S         N  NT   P+
Sbjct: 574  ISRGLQFILTPNEFSAQTFYALSPTMHSQATQVPISQSDGSAVAATNTIANQINTA--PK 631

Query: 984  PVGTVLLQIPEPQESNSDAGINLIALPAFSQVD-PEVFAALPAELQREL 1031
            P     LQIP P             LPA   +  PE     PA LQ  +
Sbjct: 632  PAAPTTLQIPPP-------------LPAIKHLPRPETLHPNPAGLQESI 667


>gi|236462079 potassium voltage-gated channel, KQT-like subfamily,
            member 5 isoform 4 [Homo sapiens]
          Length = 951

 Score = 37.7 bits (86), Expect = 0.069
 Identities = 52/229 (22%), Positives = 89/229 (38%), Gaps = 25/229 (10%)

Query: 813  MRGVGIHVNQLVPTNLNPSTCPSRPSVQSSHFPSGSYSVRD-VFQVQKAKKSTEEEHK-- 869
            ++ +   V+Q++      S   SR  + + H  +   S+   V +V+K  +S E +    
Sbjct: 583  IKSLQTRVDQILGKGQITSDKKSREKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCL 642

Query: 870  -EVFRAAVDLEISSASRTCTF-LPPFPAHLPT---SPDTNKAESSGKWNGLHTPVSVQSR 924
             ++++  +    +SA    +F +PPF     +   SP  +K  S    N      S  + 
Sbjct: 643  LDIYQQVLRKGSASALALASFQIPPFECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSAN 702

Query: 925  LNLSIE-VPSPSQLDQSVLEALPPDLREQVEQVCAVQQAESHGDKKKEPVNGCNTGILPQ 983
            ++  ++ + +P++       AL P +  Q  QV   Q   S         N  NT   P+
Sbjct: 703  ISRGLQFILTPNEFSAQTFYALSPTMHSQATQVPISQSDGSAVAATNTIANQINTA--PK 760

Query: 984  PVGTVLLQIPEPQESNSDAGINLIALPAFSQVD-PEVFAALPAELQREL 1031
            P     LQIP P             LPA   +  PE     PA LQ  +
Sbjct: 761  PAAPTTLQIPPP-------------LPAIKHLPRPETLHPNPAGLQESI 796


>gi|236461942 potassium voltage-gated channel, KQT-like subfamily,
            member 5 isoform 3 [Homo sapiens]
          Length = 942

 Score = 37.7 bits (86), Expect = 0.069
 Identities = 52/229 (22%), Positives = 89/229 (38%), Gaps = 25/229 (10%)

Query: 813  MRGVGIHVNQLVPTNLNPSTCPSRPSVQSSHFPSGSYSVRD-VFQVQKAKKSTEEEHK-- 869
            ++ +   V+Q++      S   SR  + + H  +   S+   V +V+K  +S E +    
Sbjct: 574  IKSLQTRVDQILGKGQITSDKKSREKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCL 633

Query: 870  -EVFRAAVDLEISSASRTCTF-LPPFPAHLPT---SPDTNKAESSGKWNGLHTPVSVQSR 924
             ++++  +    +SA    +F +PPF     +   SP  +K  S    N      S  + 
Sbjct: 634  LDIYQQVLRKGSASALALASFQIPPFECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSAN 693

Query: 925  LNLSIE-VPSPSQLDQSVLEALPPDLREQVEQVCAVQQAESHGDKKKEPVNGCNTGILPQ 983
            ++  ++ + +P++       AL P +  Q  QV   Q   S         N  NT   P+
Sbjct: 694  ISRGLQFILTPNEFSAQTFYALSPTMHSQATQVPISQSDGSAVAATNTIANQINTA--PK 751

Query: 984  PVGTVLLQIPEPQESNSDAGINLIALPAFSQVD-PEVFAALPAELQREL 1031
            P     LQIP P             LPA   +  PE     PA LQ  +
Sbjct: 752  PAAPTTLQIPPP-------------LPAIKHLPRPETLHPNPAGLQESI 787


>gi|236461719 potassium voltage-gated channel, KQT-like subfamily,
            member 5 isoform 2 [Homo sapiens]
          Length = 923

 Score = 37.7 bits (86), Expect = 0.069
 Identities = 52/229 (22%), Positives = 89/229 (38%), Gaps = 25/229 (10%)

Query: 813  MRGVGIHVNQLVPTNLNPSTCPSRPSVQSSHFPSGSYSVRD-VFQVQKAKKSTEEEHK-- 869
            ++ +   V+Q++      S   SR  + + H  +   S+   V +V+K  +S E +    
Sbjct: 555  IKSLQTRVDQILGKGQITSDKKSREKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCL 614

Query: 870  -EVFRAAVDLEISSASRTCTF-LPPFPAHLPT---SPDTNKAESSGKWNGLHTPVSVQSR 924
             ++++  +    +SA    +F +PPF     +   SP  +K  S    N      S  + 
Sbjct: 615  LDIYQQVLRKGSASALALASFQIPPFECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSAN 674

Query: 925  LNLSIE-VPSPSQLDQSVLEALPPDLREQVEQVCAVQQAESHGDKKKEPVNGCNTGILPQ 983
            ++  ++ + +P++       AL P +  Q  QV   Q   S         N  NT   P+
Sbjct: 675  ISRGLQFILTPNEFSAQTFYALSPTMHSQATQVPISQSDGSAVAATNTIANQINTA--PK 732

Query: 984  PVGTVLLQIPEPQESNSDAGINLIALPAFSQVD-PEVFAALPAELQREL 1031
            P     LQIP P             LPA   +  PE     PA LQ  +
Sbjct: 733  PAAPTTLQIPPP-------------LPAIKHLPRPETLHPNPAGLQESI 768


>gi|28373065 potassium voltage-gated channel, KQT-like subfamily,
            member 5 isoform 1 [Homo sapiens]
          Length = 932

 Score = 37.7 bits (86), Expect = 0.069
 Identities = 52/229 (22%), Positives = 89/229 (38%), Gaps = 25/229 (10%)

Query: 813  MRGVGIHVNQLVPTNLNPSTCPSRPSVQSSHFPSGSYSVRD-VFQVQKAKKSTEEEHK-- 869
            ++ +   V+Q++      S   SR  + + H  +   S+   V +V+K  +S E +    
Sbjct: 564  IKSLQTRVDQILGKGQITSDKKSREKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCL 623

Query: 870  -EVFRAAVDLEISSASRTCTF-LPPFPAHLPT---SPDTNKAESSGKWNGLHTPVSVQSR 924
             ++++  +    +SA    +F +PPF     +   SP  +K  S    N      S  + 
Sbjct: 624  LDIYQQVLRKGSASALALASFQIPPFECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSAN 683

Query: 925  LNLSIE-VPSPSQLDQSVLEALPPDLREQVEQVCAVQQAESHGDKKKEPVNGCNTGILPQ 983
            ++  ++ + +P++       AL P +  Q  QV   Q   S         N  NT   P+
Sbjct: 684  ISRGLQFILTPNEFSAQTFYALSPTMHSQATQVPISQSDGSAVAATNTIANQINTA--PK 741

Query: 984  PVGTVLLQIPEPQESNSDAGINLIALPAFSQVD-PEVFAALPAELQREL 1031
            P     LQIP P             LPA   +  PE     PA LQ  +
Sbjct: 742  PAAPTTLQIPPP-------------LPAIKHLPRPETLHPNPAGLQESI 777


>gi|194440660 topoisomerase (DNA) II binding protein 1 [Homo
           sapiens]
          Length = 1522

 Score = 37.7 bits (86), Expect = 0.069
 Identities = 23/76 (30%), Positives = 36/76 (47%), Gaps = 2/76 (2%)

Query: 48  IFSGVAIYVNGYTDPSAEELRKLMMLHGGQYHVYYSRSKTTHIIATNLPNAKIKELKGEK 107
           IF G  I V G      +E+++L + HGGQY      ++ TH+I       K +  K   
Sbjct: 199 IFLGCIICVTGLCGLDRKEVQQLTVKHGGQYMGQLKMNECTHLIVQEPKGQKYECAKRWN 258

Query: 108 V--IRPEWIVESIKAG 121
           V  +  +W  +SI+ G
Sbjct: 259 VHCVTTQWFFDSIEKG 274



 Score = 34.3 bits (77), Expect = 0.76
 Identities = 25/104 (24%), Positives = 48/104 (46%), Gaps = 8/104 (7%)

Query: 48  IFSGVAIYVNGYTDPSAEELRKLMMLHGGQYHVYYSRSKTTHIIATNLPNAKIKELKGEK 107
           +  G  IY+ G++    ++LR+L+   GG           TH+I  +  + ++K+   + 
Sbjct: 358 LLDGCRIYLCGFSGRKLDKLRRLIN-SGGGVRFNQLNEDVTHVIVGDYDD-ELKQFWNKS 415

Query: 108 VIRP-----EWIVESIKAGRLLSYIPYQLYTKQSSVQKGLSFNP 146
             RP     +W++E    G +LS  PY ++     V+  +S  P
Sbjct: 416 AHRPHVVGAKWLLECFSKGYMLSEEPY-IHANYQPVEIPVSHKP 458


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 35.4 bits (80), Expect = 0.34
 Identities = 49/185 (26%), Positives = 76/185 (41%), Gaps = 29/185 (15%)

Query: 957  CAVQQAESH--GDKKKEPVNGCNTGILPQPVGTVLLQIPEPQESNSDAGINLIALPAFSQ 1014
            C  Q+A S   GD +K P         P P G     +P P ES+S        +    +
Sbjct: 1109 CQTQRAISGQLGDIRKMP---------PAPSGPKASPMPVPTESSSQKTAVPPQVKLVKK 1159

Query: 1015 VDPEVFAALPAELQRELKAAYDQR---------QRQGENSTHQQSASASVPKNPLLHLKA 1065
             + EV       +  ++K               Q+Q E+   +  ASA   K PL   K 
Sbjct: 1160 QEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKK 1219

Query: 1066 AV--KEKKRNKKKKTIGSPKRIQSPLNNKLLNSPAKTLPGACGSPQKLIDGFLKHEGPPA 1123
             +  +EK R+++KK +   K+  +P + KLL   AKT      +P++     LK +   A
Sbjct: 1220 LIPEEEKIRSEEKKPLLEEKK-PTPEDKKLL-PEAKT-----SAPEEQKHDLLKSQVQIA 1272

Query: 1124 EKPLE 1128
            E+ LE
Sbjct: 1273 EEKLE 1277


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 35.4 bits (80), Expect = 0.34
 Identities = 49/185 (26%), Positives = 76/185 (41%), Gaps = 29/185 (15%)

Query: 957  CAVQQAESH--GDKKKEPVNGCNTGILPQPVGTVLLQIPEPQESNSDAGINLIALPAFSQ 1014
            C  Q+A S   GD +K P         P P G     +P P ES+S        +    +
Sbjct: 1109 CQTQRAISGQLGDIRKMP---------PAPSGPKASPMPVPTESSSQKTAVPPQVKLVKK 1159

Query: 1015 VDPEVFAALPAELQRELKAAYDQR---------QRQGENSTHQQSASASVPKNPLLHLKA 1065
             + EV       +  ++K               Q+Q E+   +  ASA   K PL   K 
Sbjct: 1160 QEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKK 1219

Query: 1066 AV--KEKKRNKKKKTIGSPKRIQSPLNNKLLNSPAKTLPGACGSPQKLIDGFLKHEGPPA 1123
             +  +EK R+++KK +   K+  +P + KLL   AKT      +P++     LK +   A
Sbjct: 1220 LIPEEEKIRSEEKKPLLEEKK-PTPEDKKLL-PEAKT-----SAPEEQKHDLLKSQVQIA 1272

Query: 1124 EKPLE 1128
            E+ LE
Sbjct: 1273 EEKLE 1277


>gi|110611228 utrophin [Homo sapiens]
          Length = 3433

 Score = 35.0 bits (79), Expect = 0.45
 Identities = 45/207 (21%), Positives = 78/207 (37%), Gaps = 29/207 (14%)

Query: 151  EDPLPGPSNIAKQLNNRVNHIVKKIETENEVKVNGMNSWNEEDENNDFSFVDLEQTSPGR 210
            E P+  P + A+        I+K +E E   ++  + +  EE++ N    V+ EQ     
Sbjct: 3239 ESPVSQPQSPAQ--------ILKSVEREERGELERIIADLEEEQRN--LQVEYEQLKDQH 3288

Query: 211  KQNGIPHPRGSTAIFNGHTPSSNGALKTQDCLVPMVNSVASRLSPAFSQEEDKAEKSSTD 270
             + G+P      +I + H  S +  L  +     ++     RL       ED  ++  + 
Sbjct: 3289 LRRGLPVGSPPESIISPHHTSEDSELIAE---AKLLRQHKGRLEARMQILEDHNKQLESQ 3345

Query: 271  FRDCTLQQLQQSTRNTDALRN-------PHRTNSFSLSPLHSNTKINGAHHSTVQGPSST 323
                 L+QL +   +   +          H   S+SL P  S  + + A    +  P   
Sbjct: 3346 LH--RLRQLLEQPESDSRINGVSPWASPQHSALSYSLDPDASGPQFHQAAGEDLLAPPHD 3403

Query: 324  KSTSSV-------STFSKAAPSVPSKP 343
             ST          STF    P+VPS+P
Sbjct: 3404 TSTDLTEVMEQIHSTFPSCCPNVPSRP 3430


>gi|7657218 bromodomain-containing protein 4 isoform short [Homo
            sapiens]
          Length = 722

 Score = 34.7 bits (78), Expect = 0.59
 Identities = 41/166 (24%), Positives = 73/166 (43%), Gaps = 23/166 (13%)

Query: 967  DKKKEPVNGCNTGILPQPVGTVLLQIPEPQESNSDAGINLIALPAFSQVDPEVFAALPAE 1026
            D+ +EPV   ++  +P P  T ++  P   +S+SD+  +  +    S+   E  A   AE
Sbjct: 459  DEPEEPVVAVSSPAVPPP--TKVVAPPSSSDSSSDSSSDSDSSTDDSE---EERAQRLAE 513

Query: 1027 LQRELKAAYDQ---RQRQGENSTHQQSASASVPKNPLLHLKAAVKEKKRNKKKKTIGSPK 1083
            LQ +LKA ++Q     +  +N   ++       K      K  V+E K++K K+    PK
Sbjct: 514  LQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEP--PPK 571

Query: 1084 RIQSPLNNKLLNSPAKTLPGACGSPQKLIDGFLKHEGPPAEKPLEE 1129
            + +   NN   ++ +K  P             +K + PP  +  EE
Sbjct: 572  KTKK--NNSSNSNVSKKEPAP-----------MKSKPPPTYESEEE 604


>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
            sapiens]
          Length = 1362

 Score = 34.7 bits (78), Expect = 0.59
 Identities = 41/166 (24%), Positives = 73/166 (43%), Gaps = 23/166 (13%)

Query: 967  DKKKEPVNGCNTGILPQPVGTVLLQIPEPQESNSDAGINLIALPAFSQVDPEVFAALPAE 1026
            D+ +EPV   ++  +P P  T ++  P   +S+SD+  +  +    S+   E  A   AE
Sbjct: 459  DEPEEPVVAVSSPAVPPP--TKVVAPPSSSDSSSDSSSDSDSSTDDSE---EERAQRLAE 513

Query: 1027 LQRELKAAYDQ---RQRQGENSTHQQSASASVPKNPLLHLKAAVKEKKRNKKKKTIGSPK 1083
            LQ +LKA ++Q     +  +N   ++       K      K  V+E K++K K+    PK
Sbjct: 514  LQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEP--PPK 571

Query: 1084 RIQSPLNNKLLNSPAKTLPGACGSPQKLIDGFLKHEGPPAEKPLEE 1129
            + +   NN   ++ +K  P             +K + PP  +  EE
Sbjct: 572  KTKK--NNSSNSNVSKKEPAP-----------MKSKPPPTYESEEE 604


>gi|239757877 PREDICTED: FERM and PDZ domain containing 3 [Homo
            sapiens]
          Length = 1662

 Score = 34.3 bits (77), Expect = 0.76
 Identities = 33/118 (27%), Positives = 49/118 (41%), Gaps = 15/118 (12%)

Query: 284  RNTDALRNPHRTNSFSLSPLHS-NTKINGAHHSTVQGPSSTKSTSSV----STFSKAAPS 338
            R    LR+   +   S  P     T +NGAH ST +GP+  KS+       + FS   P+
Sbjct: 1053 RGQSPLRSQAASRQVSTMPSRKLETTLNGAH-STSEGPAKPKSSRGPFRLRNLFSATFPT 1111

Query: 339  VPSKPSDCNFISNFYSHSRLHHISMWKCELTEFVNTLQRQSNGIFPGREKLKKMKTGR 396
               K +D          ++L  +  ++ E  E    L+  S G  PG E L+    GR
Sbjct: 1112 RQKKETD-------ERQAQLQKVKQYELEFLE--ELLKPPSQGELPGTEYLQPPAPGR 1160


>gi|89060961 PREDICTED: FERM and PDZ domain containing 3 [Homo
            sapiens]
          Length = 1810

 Score = 34.3 bits (77), Expect = 0.76
 Identities = 33/118 (27%), Positives = 49/118 (41%), Gaps = 15/118 (12%)

Query: 284  RNTDALRNPHRTNSFSLSPLHS-NTKINGAHHSTVQGPSSTKSTSSV----STFSKAAPS 338
            R    LR+   +   S  P     T +NGAH ST +GP+  KS+       + FS   P+
Sbjct: 1201 RGQSPLRSQAASRQVSTMPSRKLETTLNGAH-STSEGPAKPKSSRGPFRLRNLFSATFPT 1259

Query: 339  VPSKPSDCNFISNFYSHSRLHHISMWKCELTEFVNTLQRQSNGIFPGREKLKKMKTGR 396
               K +D          ++L  +  ++ E  E    L+  S G  PG E L+    GR
Sbjct: 1260 RQKKETD-------ERQAQLQKVKQYELEFLE--ELLKPPSQGELPGTEYLQPPAPGR 1308


>gi|89059963 PREDICTED: FERM and PDZ domain containing 3 [Homo
            sapiens]
          Length = 1810

 Score = 34.3 bits (77), Expect = 0.76
 Identities = 33/118 (27%), Positives = 49/118 (41%), Gaps = 15/118 (12%)

Query: 284  RNTDALRNPHRTNSFSLSPLHS-NTKINGAHHSTVQGPSSTKSTSSV----STFSKAAPS 338
            R    LR+   +   S  P     T +NGAH ST +GP+  KS+       + FS   P+
Sbjct: 1201 RGQSPLRSQAASRQVSTMPSRKLETTLNGAH-STSEGPAKPKSSRGPFRLRNLFSATFPT 1259

Query: 339  VPSKPSDCNFISNFYSHSRLHHISMWKCELTEFVNTLQRQSNGIFPGREKLKKMKTGR 396
               K +D          ++L  +  ++ E  E    L+  S G  PG E L+    GR
Sbjct: 1260 RQKKETD-------ERQAQLQKVKQYELEFLE--ELLKPPSQGELPGTEYLQPPAPGR 1308


>gi|83367077 mucin 16 [Homo sapiens]
          Length = 14507

 Score = 33.9 bits (76), Expect = 1.00
 Identities = 30/111 (27%), Positives = 47/111 (42%), Gaps = 6/111 (5%)

Query: 232  SNGALKTQDCLVPMVNSVASRLSPAFSQEEDKAEKSSTDFRDCTLQQLQQSTRNTDALRN 291
            S+  +  Q    P VNSVA   SP           +S+ +   +L+ L  +    +A+ +
Sbjct: 1991 SSEKVSVQTQSTPYVNSVAVSASPTHENSVSSGSSTSSPYSSASLESLDSTISRRNAITS 2050

Query: 292  PHRTNSFSLS----PLHSNTKINGAHHSTVQGPSSTKSTSSVSTFSKAAPS 338
                 + SL     P  S ++   + HS V  PSST  T+    FS A+ S
Sbjct: 2051 WLWDLTTSLPTTTWPSTSLSEALSSGHSGVSNPSST--TTEFPLFSAASTS 2099


>gi|239754668 PREDICTED: mucin 12 [Homo sapiens]
          Length = 1952

 Score = 33.9 bits (76), Expect = 1.00
 Identities = 33/128 (25%), Positives = 48/128 (37%), Gaps = 16/128 (12%)

Query: 248 SVASRLSPAFSQEEDKAEKSSTDFRDCTLQQLQQSTRNTDALRNPHRTNSFSL----SPL 303
           S  + LSP  +       +S+T            S   T   R P  T +  L    +P+
Sbjct: 266 STDTTLSPGTTTPSSLGPESTT---------FHSSPGYTKTTRLPDNTTTSGLLEASTPV 316

Query: 304 HSNTKINGAHHSTVQGPSSTKSTSSVSTFSKAAPSVPSKPSDCNFISNFYSHSRLHHISM 363
           HS+T   G+ H+T+   SST      +TF     S  + P+     S F   S  +H S 
Sbjct: 317 HSST---GSPHTTLSPASSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSP 373

Query: 364 WKCELTEF 371
                T F
Sbjct: 374 SSTPTTHF 381


>gi|239749217 PREDICTED: similar to Mucin-12, partial [Homo sapiens]
          Length = 861

 Score = 33.9 bits (76), Expect = 1.00
 Identities = 33/128 (25%), Positives = 48/128 (37%), Gaps = 16/128 (12%)

Query: 248 SVASRLSPAFSQEEDKAEKSSTDFRDCTLQQLQQSTRNTDALRNPHRTNSFSL----SPL 303
           S  + LSP  +       +S+T            S   T   R P  T +  L    +P+
Sbjct: 201 STDTTLSPGTTTPSSLGPESTT---------FHSSPGYTKTTRLPDNTTTSGLLEASTPV 251

Query: 304 HSNTKINGAHHSTVQGPSSTKSTSSVSTFSKAAPSVPSKPSDCNFISNFYSHSRLHHISM 363
           HS+T   G+ H+T+   SST      +TF     S  + P+     S F   S  +H S 
Sbjct: 252 HSST---GSPHTTLSPSSSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSP 308

Query: 364 WKCELTEF 371
                T F
Sbjct: 309 SSTPTTHF 316


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score = 33.9 bits (76), Expect = 1.00
 Identities = 33/128 (25%), Positives = 48/128 (37%), Gaps = 16/128 (12%)

Query: 248 SVASRLSPAFSQEEDKAEKSSTDFRDCTLQQLQQSTRNTDALRNPHRTNSFSL----SPL 303
           S  + LSP  +       +S+T            S   T   R P  T +  L    +P+
Sbjct: 345 STDTTLSPGTTTPSSLGPESTT---------FHSSPGYTKTTRLPDNTTTSGLLEASTPV 395

Query: 304 HSNTKINGAHHSTVQGPSSTKSTSSVSTFSKAAPSVPSKPSDCNFISNFYSHSRLHHISM 363
           HS+T   G+ H+T+   SST      +TF     S  + P+     S F   S  +H S 
Sbjct: 396 HSST---GSPHTTLSPSSSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSP 452

Query: 364 WKCELTEF 371
                T F
Sbjct: 453 SSTPTTHF 460


>gi|239745855 PREDICTED: hypothetical protein XP_002343606 [Homo
            sapiens]
          Length = 870

 Score = 33.5 bits (75), Expect = 1.3
 Identities = 38/170 (22%), Positives = 62/170 (36%), Gaps = 14/170 (8%)

Query: 898  PTSPDTNKAESSGKWNGLHTPVSVQSRLNLSIEVPSPSQ---LDQSVLEALPPDLREQV- 953
            P  P  +  E         TP        +++  P   Q   LD   +   PPD++  + 
Sbjct: 363  PVQPSESSREVESSLTQQETPGQPPEHHEVTVSPPGHHQTHHLDSPSVSVKPPDVQLTIA 422

Query: 954  -EQVCAVQQAESHGDKKKEPVNGCNTGILPQPV---GTVLLQIPEPQESNSDAGINLIAL 1009
             E    V  +  H +     ++G    + P  +   G  LL      ES+ +AG   +  
Sbjct: 423  AEPSAEVGTSLVHQEATAR-LSGSGNDVEPPAIQHGGPPLLP-----ESSEEAGPLAVQQ 476

Query: 1010 PAFSQVDPEVFAALPAELQRELKAAYDQRQRQGENSTHQQSASASVPKNP 1059
                Q    +    P+  Q+E  A + Q   +GE+S   Q A A  P+ P
Sbjct: 477  ETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFP 526


>gi|151301154 mucin 6, gastric [Homo sapiens]
          Length = 2439

 Score = 33.1 bits (74), Expect = 1.7
 Identities = 29/127 (22%), Positives = 52/127 (40%), Gaps = 14/127 (11%)

Query: 218  PRGSTAIFNGHTPSSNGALKTQDCLVPMVNSVASRLSPAFSQEEDKAEKSSTDFRDCTLQ 277
            PR +TA+    TP +   L       P     ++   P  +Q   +A  S+      T  
Sbjct: 1272 PRPTTAV----TPQATSGLP------PTATLRSTATKPTVTQATTRATASTAS--PATTS 1319

Query: 278  QLQQSTRNTDALRNPHRTNSFSLSPLHSNTKINGAHHSTVQGPSSTKSTSSVSTFSKAAP 337
              Q +TR T  L  P  + +    P  +N ++ G   +   GP  T ++++  T  +  P
Sbjct: 1320 TAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTGPTTPQ--P 1377

Query: 338  SVPSKPS 344
              P++P+
Sbjct: 1378 GQPTRPT 1384



 Score = 32.3 bits (72), Expect = 2.9
 Identities = 28/129 (21%), Positives = 57/129 (44%), Gaps = 10/129 (7%)

Query: 230  PSSNGALKTQDCLVPMVNSVASRLSPAFSQEEDKAEKSSTDFRDCTLQQLQQSTRNTDAL 289
            P ++ +      +   +  ++S  +P  +  +  +  S +     T+     S+ ++   
Sbjct: 2095 PQNSSSRPPSSPITTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQT 2154

Query: 290  RNPH--RTNSFSLSPLHSNTKINGAHHSTVQGPSSTKSTSSVSTFSKAAPSVPSKPSDCN 347
             +P    ++SF  +P+HS T  +G+H S     S+  +T+SVS    A+P  PS P+   
Sbjct: 2155 SSPSVGTSSSFVSAPVHSTTLSSGSHSSL----STHPTTASVS----ASPLFPSSPAAST 2206

Query: 348  FISNFYSHS 356
             I     H+
Sbjct: 2207 TIRATLPHT 2215


>gi|154091020 leucine-rich repeats and calponin homology (CH) domain
           containing 2 [Homo sapiens]
          Length = 765

 Score = 32.7 bits (73), Expect = 2.2
 Identities = 29/134 (21%), Positives = 55/134 (41%), Gaps = 11/134 (8%)

Query: 164 LNNRVNHIVKKIETENEVKVNGMNSWNEEDENNDFSFVDLEQTSPGRKQNGIPHPRGSTA 223
           L+++V+   ++  + N+  + G  + +++D+   + FVD         + G  H     +
Sbjct: 371 LHSQVSESNREQTSRNDSHIIGSKTDSQKDQEV-YDFVDPNTEDVAVPEQGNAHIGSFVS 429

Query: 224 IFNGHTPSSNGALKTQDCLVPMVNSVASRLSPAFSQEEDKAEKSSTDFRDCTLQQLQQST 283
            F G    S  + K ++    + +          ++EED   K  TD R    Q LQQ  
Sbjct: 430 FFKGKEKCSEKSRKNEE----LGDEKRLEKEQLLAEEEDDDLKEVTDLRKIAAQLLQQEQ 485

Query: 284 RN------TDALRN 291
           +N      T  +RN
Sbjct: 486 KNRILNHSTSVMRN 499


>gi|161016767 mucin 21 [Homo sapiens]
          Length = 566

 Score = 32.7 bits (73), Expect = 2.2
 Identities = 32/147 (21%), Positives = 63/147 (42%), Gaps = 4/147 (2%)

Query: 195 NNDFSFVDLEQTSPGRKQNGIPHPRGSTAIFNGHTPSSNGALKTQDCLVPMVNSVASRLS 254
           N++ S      ++    ++  P    STA  +  + +S+GA    +      +S AS  +
Sbjct: 107 NSESSTTSSGASTATNSESSTPSSGASTATNSDSSTTSSGASTATNSDSSTTSSEASTAT 166

Query: 255 PAFSQEEDKAEKSSTDFRDCTLQQLQQSTRNTDALRNPHRTNSFSLSPLHSNTKINGAHH 314
            + S        ++T+    T+     +  N+++       ++ + S   S T  NGA  
Sbjct: 167 NSESSTTSSGASTATNSESSTVSSRASTATNSESSTTSSGASTATNS--ESRTTSNGAGT 224

Query: 315 STVQGPSSTKSTSSVSTFSKAAPSVPS 341
           +T    S+T S +S +T S++  S PS
Sbjct: 225 ATNSESSTTSSGASTATNSES--STPS 249



 Score = 32.0 bits (71), Expect = 3.8
 Identities = 37/150 (24%), Positives = 62/150 (41%), Gaps = 11/150 (7%)

Query: 195 NNDFSFVDLEQTSPGRKQNGIPHPRGSTAIFNGHTPSSNGALKTQDCLVPMVNSVASRLS 254
           N++ S V    ++    ++  P    +TA  +  + +S+GA           NS +S  S
Sbjct: 272 NSESSTVSSGISTVTNSESSTPSSGANTATNSESSTTSSGANTA-------TNSDSSTTS 324

Query: 255 PAFSQEEDKAEKSSTDFRDCTLQQLQQSTRNTDALRNPHRTNSFSLSPLHSNTKINGAHH 314
              S   + +E S+T     T    + ST ++ A      TNS S +     +    +  
Sbjct: 325 SGASTATN-SESSTTSSGASTATNSESSTTSSGAST---ATNSGSSTTSSGTSTATNSES 380

Query: 315 STVQGPSSTKSTSSVSTFSKAAPSVPSKPS 344
           STV   +ST +TS  ST S  A +  +  S
Sbjct: 381 STVSSGASTATTSESSTTSSGASTATNSES 410


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.130    0.377 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 49,877,088
Number of Sequences: 37866
Number of extensions: 2401448
Number of successful extensions: 6400
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 53
Number of HSP's that attempted gapping in prelim test: 6277
Number of HSP's gapped (non-prelim): 180
length of query: 1250
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1136
effective length of database: 13,930,794
effective search space: 15825381984
effective search space used: 15825381984
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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