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Search of human proteins with 8400718
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|8400718 RNA binding motif, single stranded interacting
protein 1 isoform a [Homo sapiens]
(406 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|8400718 RNA binding motif, single stranded interacting protei... 829 0.0
gi|4506447 RNA binding motif, single stranded interacting protei... 819 0.0
gi|51317351 RNA binding motif, single stranded interacting prote... 608 e-174
gi|51317355 RNA binding motif, single stranded interacting prote... 597 e-171
gi|51317353 RNA binding motif, single stranded interacting prote... 562 e-160
gi|4506449 RNA binding motif, single stranded interacting protei... 546 e-155
gi|115511032 ELAV (embryonic lethal, abnormal vision, Drosophila... 126 4e-29
gi|221316773 ELAV-like 4 isoform 5 [Homo sapiens] 117 2e-26
gi|221316771 ELAV-like 4 isoform 4 [Homo sapiens] 117 2e-26
gi|221316765 ELAV-like 4 isoform 1 [Homo sapiens] 116 4e-26
gi|221316769 ELAV-like 4 isoform 3 [Homo sapiens] 116 4e-26
gi|221316767 ELAV-like 4 isoform 2 [Homo sapiens] 116 4e-26
gi|49355761 ELAV-like protein 3 isoform 1 [Homo sapiens] 110 3e-24
gi|49355765 ELAV-like protein 3 isoform 2 [Homo sapiens] 110 3e-24
gi|38201714 ELAV-like 1 [Homo sapiens] 103 2e-22
gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens] 91 2e-18
gi|185135971 poly(A)-binding protein, cytoplasmic 1-like [Homo s... 86 5e-17
gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens] 81 2e-15
gi|24762232 bruno-like 5, RNA binding protein isoform 1 [Homo sa... 79 7e-15
gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Ho... 79 7e-15
gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo... 79 7e-15
gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Ho... 79 7e-15
gi|109948285 poly(A) binding protein, cytoplasmic 1-like 2B [Hom... 77 4e-14
gi|61175237 poly(A) binding protein, cytoplasmic 1-like 2A [Homo... 77 4e-14
gi|18201888 poly(A) binding protein, cytoplasmic 5 [Homo sapiens] 76 6e-14
gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo s... 75 1e-13
gi|71164894 trinucleotide repeat containing 4 [Homo sapiens] 73 4e-13
gi|187761303 bruno-like 4, RNA binding protein isoform 4 [Homo s... 67 4e-11
gi|68303647 CUG triplet repeat, RNA binding protein 2 isoform 3 ... 64 2e-10
gi|70780381 bruno-like 6, RNA binding protein [Homo sapiens] 64 2e-10
>gi|8400718 RNA binding motif, single stranded interacting protein 1
isoform a [Homo sapiens]
Length = 406
Score = 829 bits (2142), Expect = 0.0
Identities = 406/406 (100%), Positives = 406/406 (100%)
Query: 1 MGKVWKQQMYPQYATYYYPQYLQAKQSLVPAHPMAPPSPSTTSSNNNSSSSSNSGWDQLS 60
MGKVWKQQMYPQYATYYYPQYLQAKQSLVPAHPMAPPSPSTTSSNNNSSSSSNSGWDQLS
Sbjct: 1 MGKVWKQQMYPQYATYYYPQYLQAKQSLVPAHPMAPPSPSTTSSNNNSSSSSNSGWDQLS 60
Query: 61 KTNLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPAAAQKAV 120
KTNLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPAAAQKAV
Sbjct: 61 KTNLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPAAAQKAV 120
Query: 121 SALKASGVQAQMAKQQEQDPTNLYISNLPLSMDEQELENMLKPFGQVISTRILRDSSGTS 180
SALKASGVQAQMAKQQEQDPTNLYISNLPLSMDEQELENMLKPFGQVISTRILRDSSGTS
Sbjct: 121 SALKASGVQAQMAKQQEQDPTNLYISNLPLSMDEQELENMLKPFGQVISTRILRDSSGTS 180
Query: 181 RGVGFARMESTEKCEAVIGHFNGKFIKTPPGVSAPTEPLLCKFADGGQKKRQNPNKYIPN 240
RGVGFARMESTEKCEAVIGHFNGKFIKTPPGVSAPTEPLLCKFADGGQKKRQNPNKYIPN
Sbjct: 181 RGVGFARMESTEKCEAVIGHFNGKFIKTPPGVSAPTEPLLCKFADGGQKKRQNPNKYIPN 240
Query: 241 GRPWHREGEVRLAGMTLTYDPTTAAIQNGFYPSPYSIATNRMITQTSITPYIASPVSAYQ 300
GRPWHREGEVRLAGMTLTYDPTTAAIQNGFYPSPYSIATNRMITQTSITPYIASPVSAYQ
Sbjct: 241 GRPWHREGEVRLAGMTLTYDPTTAAIQNGFYPSPYSIATNRMITQTSITPYIASPVSAYQ 300
Query: 301 VQSPSWMQPQPYILQHPGAVLTPSMEHTMSLQPASMISPLAQQMSHLSLGSTGTYMPATS 360
VQSPSWMQPQPYILQHPGAVLTPSMEHTMSLQPASMISPLAQQMSHLSLGSTGTYMPATS
Sbjct: 301 VQSPSWMQPQPYILQHPGAVLTPSMEHTMSLQPASMISPLAQQMSHLSLGSTGTYMPATS 360
Query: 361 AMQGAYLPQYAHMQTTAVPVEEASGQQQVAVETSNDHSPYTFQPNK 406
AMQGAYLPQYAHMQTTAVPVEEASGQQQVAVETSNDHSPYTFQPNK
Sbjct: 361 AMQGAYLPQYAHMQTTAVPVEEASGQQQVAVETSNDHSPYTFQPNK 406
>gi|4506447 RNA binding motif, single stranded interacting protein 1
isoform c [Homo sapiens]
Length = 403
Score = 819 bits (2115), Expect = 0.0
Identities = 403/406 (99%), Positives = 403/406 (99%), Gaps = 3/406 (0%)
Query: 1 MGKVWKQQMYPQYATYYYPQYLQAKQSLVPAHPMAPPSPSTTSSNNNSSSSSNSGWDQLS 60
MGKVWKQQMYPQYATYYYPQYLQAKQSLVPAHPMAPPSPSTTSSNNNSSSSSNSGWDQLS
Sbjct: 1 MGKVWKQQMYPQYATYYYPQYLQAKQSLVPAHPMAPPSPSTTSSNNNSSSSSNSGWDQLS 60
Query: 61 KTNLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPAAAQKAV 120
KTNLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPAAAQKAV
Sbjct: 61 KTNLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPAAAQKAV 120
Query: 121 SALKASGVQAQMAKQQEQDPTNLYISNLPLSMDEQELENMLKPFGQVISTRILRDSSGTS 180
SALKASGVQAQMAKQQEQDPTNLYISNLPLSMDEQELENMLKPFGQVISTRILRDSSGTS
Sbjct: 121 SALKASGVQAQMAKQQEQDPTNLYISNLPLSMDEQELENMLKPFGQVISTRILRDSSGTS 180
Query: 181 RGVGFARMESTEKCEAVIGHFNGKFIKTPPGVSAPTEPLLCKFADGGQKKRQNPNKYIPN 240
RGVGFARMESTEKCEAVIGHFNGKFIKTPPGVSAPTEPLLCKFADGGQKKRQNPNKYIPN
Sbjct: 181 RGVGFARMESTEKCEAVIGHFNGKFIKTPPGVSAPTEPLLCKFADGGQKKRQNPNKYIPN 240
Query: 241 GRPWHREGEVRLAGMTLTYDPTTAAIQNGFYPSPYSIATNRMITQTSITPYIASPVSAYQ 300
GRPWHREGE AGMTLTYDPTTAAIQNGFYPSPYSIATNRMITQTSITPYIASPVSAYQ
Sbjct: 241 GRPWHREGE---AGMTLTYDPTTAAIQNGFYPSPYSIATNRMITQTSITPYIASPVSAYQ 297
Query: 301 VQSPSWMQPQPYILQHPGAVLTPSMEHTMSLQPASMISPLAQQMSHLSLGSTGTYMPATS 360
VQSPSWMQPQPYILQHPGAVLTPSMEHTMSLQPASMISPLAQQMSHLSLGSTGTYMPATS
Sbjct: 298 VQSPSWMQPQPYILQHPGAVLTPSMEHTMSLQPASMISPLAQQMSHLSLGSTGTYMPATS 357
Query: 361 AMQGAYLPQYAHMQTTAVPVEEASGQQQVAVETSNDHSPYTFQPNK 406
AMQGAYLPQYAHMQTTAVPVEEASGQQQVAVETSNDHSPYTFQPNK
Sbjct: 358 AMQGAYLPQYAHMQTTAVPVEEASGQQQVAVETSNDHSPYTFQPNK 403
>gi|51317351 RNA binding motif, single stranded interacting protein
3 isoform 2 [Homo sapiens]
Length = 420
Score = 608 bits (1567), Expect = e-174
Identities = 315/427 (73%), Positives = 354/427 (82%), Gaps = 28/427 (6%)
Query: 1 MGKVWKQ-QMYPQYATYYYPQYLQAKQSLVPA-HPMAPPSPSTTSSNNNSSSSSNSGWDQ 58
MGK Q QMYPQY TYYYP YLQ KQS PA HPMAPPSPST SS+NNSS+ NS +Q
Sbjct: 1 MGKRLDQPQMYPQY-TYYYPHYLQTKQSYAPAPHPMAPPSPSTNSSSNNSSN--NSSGEQ 57
Query: 59 LSKTNLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPAAAQK 118
LSKTNLYIRGLPP TTDQDL+KLCQPYGKIVSTKAILDK TN+CKGYGFVDFDSPAAAQK
Sbjct: 58 LSKTNLYIRGLPPGTTDQDLIKLCQPYGKIVSTKAILDKNTNQCKGYGFVDFDSPAAAQK 117
Query: 119 AVSALKASGVQAQMAKQQEQDPTNLYISNLPLSMDEQELENMLKPFGQVISTRILRDSSG 178
AV++LKA+GVQAQMAKQQEQDPTNLYISNLP+SMDEQELENMLKPFG VISTRILRD++G
Sbjct: 118 AVASLKANGVQAQMAKQQEQDPTNLYISNLPISMDEQELENMLKPFGHVISTRILRDANG 177
Query: 179 TSRGVGFARMESTEKCEAVIGHFNGKFIKTPPGVSAPTEPLLCKFADGGQKKRQNPNKYI 238
SRGVGFARMESTEKCE VI HFNGK++KTPPG+ AP+EPLLCKFADGGQKKRQN +KY
Sbjct: 178 VSRGVGFARMESTEKCEVVIQHFNGKYLKTPPGIPAPSEPLLCKFADGGQKKRQNQSKYT 237
Query: 239 PNGRPWHREGEVRLAGMTLTYDPTTAAIQNGFYPSPYSIATNRMITQTSITPYI-ASPVS 297
NGRPW REGE AGM LTYDP TAAIQNGFY SPYSIATNRMI QTSITP+I ASPVS
Sbjct: 238 QNGRPWPREGE---AGMALTYDP-TAAIQNGFYSSPYSIATNRMIPQTSITPFIAASPVS 293
Query: 298 AYQVQSPSWMQPQPYILQHPGAVLTPSMEHTMSLQPASMISPLAQQMSHLSLGSTGTYMP 357
YQVQS SWM PY++Q GAV+TP+M+H MS+QPA+M+ PL QQM+HLSLG+TGTYM
Sbjct: 294 TYQVQSTSWMPHPPYVMQPTGAVITPTMDHPMSMQPANMMGPLTQQMNHLSLGTTGTYMT 353
Query: 358 ATSAMQGAYLPQYAHMQTTAVPVE----------------EASG-QQQVAVETSNDHSP- 399
A + MQG Y+PQY + TAV +E + SG QQQ+AV+TSN+H+P
Sbjct: 354 AAAPMQGTYIPQYTPVPPTAVSIEGVVADTSPQTVAPSSQDTSGQQQQIAVDTSNEHAPA 413
Query: 400 YTFQPNK 406
Y++Q +K
Sbjct: 414 YSYQQSK 420
>gi|51317355 RNA binding motif, single stranded interacting protein
3 isoform 1 [Homo sapiens]
Length = 437
Score = 597 bits (1540), Expect = e-171
Identities = 315/443 (71%), Positives = 354/443 (79%), Gaps = 44/443 (9%)
Query: 1 MGKVWKQ-QMYPQYATYYYPQYLQAKQSLVPA-HPMAPPSPSTTSSNNNSSSSSNSGWDQ 58
MGK Q QMYPQY TYYYP YLQ KQS PA HPMAPPSPST SS+NNSS+ NS +Q
Sbjct: 1 MGKRLDQPQMYPQY-TYYYPHYLQTKQSYAPAPHPMAPPSPSTNSSSNNSSN--NSSGEQ 57
Query: 59 LSKTNLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPAAAQK 118
LSKTNLYIRGLPP TTDQDL+KLCQPYGKIVSTKAILDK TN+CKGYGFVDFDSPAAAQK
Sbjct: 58 LSKTNLYIRGLPPGTTDQDLIKLCQPYGKIVSTKAILDKNTNQCKGYGFVDFDSPAAAQK 117
Query: 119 AVSALKASGVQAQMAKQQEQDPTNLYISNLPLSMDEQELENMLKPFGQVISTRILRDSSG 178
AV++LKA+GVQAQMAKQQEQDPTNLYISNLP+SMDEQELENMLKPFG VISTRILRD++G
Sbjct: 118 AVASLKANGVQAQMAKQQEQDPTNLYISNLPISMDEQELENMLKPFGHVISTRILRDANG 177
Query: 179 TSRGVGFARMESTEKCEAVIGHFNGKFIKTPPGVSAPTEPLLCKFADGGQKKRQNPNKYI 238
SRGVGFARMESTEKCE VI HFNGK++KTPPG+ AP+EPLLCKFADGGQKKRQN +KY
Sbjct: 178 VSRGVGFARMESTEKCEVVIQHFNGKYLKTPPGIPAPSEPLLCKFADGGQKKRQNQSKYT 237
Query: 239 PNGRPWHREGEVRLAGMTLTYDPTTAAIQNGFYPSPYSIATNRMITQTSITPYI-ASPVS 297
NGRPW REGE AGM LTYDP TAAIQNGFY SPYSIATNRMI QTSITP+I ASPVS
Sbjct: 238 QNGRPWPREGE---AGMALTYDP-TAAIQNGFYSSPYSIATNRMIPQTSITPFIAASPVS 293
Query: 298 AYQVQSPSWMQPQPYILQHPGAVLTPSMEHTMSLQPASMISPLAQQMSHLSLGSTGT--- 354
YQVQS SWM PY++Q GAV+TP+M+H MS+QPA+M+ PL QQM+HLSLG+TGT
Sbjct: 294 TYQVQSTSWMPHPPYVMQPTGAVITPTMDHPMSMQPANMMGPLTQQMNHLSLGTTGTIQS 353
Query: 355 -------------YMPATSAMQGAYLPQYAHMQTTAVPVE----------------EASG 385
YM A + MQG Y+PQY + TAV +E + SG
Sbjct: 354 QDRIMILHQLLCQYMTAAAPMQGTYIPQYTPVPPTAVSIEGVVADTSPQTVAPSSQDTSG 413
Query: 386 -QQQVAVETSNDHSP-YTFQPNK 406
QQQ+AV+TSN+H+P Y++Q +K
Sbjct: 414 QQQQIAVDTSNEHAPAYSYQQSK 436
>gi|51317353 RNA binding motif, single stranded interacting protein
3 isoform 3 [Homo sapiens]
Length = 419
Score = 562 bits (1449), Expect = e-160
Identities = 302/442 (68%), Positives = 339/442 (76%), Gaps = 60/442 (13%)
Query: 1 MGKVWKQ-QMYPQYATYYYPQYLQAKQSLVPAHPMAPPSPSTTSSNNNSSSSSNSGWDQL 59
MGK Q QMYPQY TYYYP YLQ K HPMAPPSPST SS+NNSS+ NS +QL
Sbjct: 1 MGKRLDQPQMYPQY-TYYYPHYLQTKSYAPAPHPMAPPSPSTNSSSNNSSN--NSSGEQL 57
Query: 60 SKTNLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPAAAQKA 119
SKTNLYIRGLPP TTDQDL+KLCQPYGKIVSTKAILDK TN+CKGYGFVDFDSPAAAQKA
Sbjct: 58 SKTNLYIRGLPPGTTDQDLIKLCQPYGKIVSTKAILDKNTNQCKGYGFVDFDSPAAAQKA 117
Query: 120 VSALKASGVQAQMAKQQEQDPTNLYISNLPLSMDEQELENMLKPFGQVISTRILRDSSGT 179
V++LKA+GVQAQMAKQQEQDPTNLYISNLP+SMDEQELENMLKPFG VISTRILRD++G
Sbjct: 118 VASLKANGVQAQMAKQQEQDPTNLYISNLPISMDEQELENMLKPFGHVISTRILRDANGV 177
Query: 180 SRGVGFARMESTEKCEAVIGHFNGKFIKTPPGVSAPTEPLLCKFADGGQKKRQNPNKYIP 239
SRGVGFARMESTEKCE VI HFNGK++KTPPG+ AP+EPLLCKFADGGQKKRQN +KY
Sbjct: 178 SRGVGFARMESTEKCEVVIQHFNGKYLKTPPGIPAPSEPLLCKFADGGQKKRQNQSKYTQ 237
Query: 240 NGRPWHREGEVRLAGMTLTYDPTTAAIQNGFYPSPYSIATNRMITQTSITPYI-ASPVSA 298
NGRPW REGE AGM LTYDP TAAIQNGFY SPYSIATNRMI QTSITP+I ASPVS
Sbjct: 238 NGRPWPREGE---AGMALTYDP-TAAIQNGFYSSPYSIATNRMIPQTSITPFIAASPVST 293
Query: 299 YQVQSPSWMQPQPYILQHPGAVLTPSMEHTMSLQPASMISPLAQQMSHLSLGSTGT---- 354
YQ GAV+TP+M+H MS+QPA+M+ PL QQM+HLSLG+TGT
Sbjct: 294 YQ-----------------GAVITPTMDHPMSMQPANMMGPLTQQMNHLSLGTTGTIQSQ 336
Query: 355 ------------YMPATSAMQGAYLPQYAHMQTTAVPVE----------------EASG- 385
YM A + MQG Y+PQY + TAV +E + SG
Sbjct: 337 DRIMILHQLLCQYMTAAAPMQGTYIPQYTPVPPTAVSIEGVVADTSPQTVAPSSQDTSGQ 396
Query: 386 QQQVAVETSNDHSP-YTFQPNK 406
QQQ+AV+TSN+H+P Y++Q +K
Sbjct: 397 QQQIAVDTSNEHAPAYSYQQSK 418
>gi|4506449 RNA binding motif, single stranded interacting protein 2
[Homo sapiens]
Length = 407
Score = 546 bits (1408), Expect = e-155
Identities = 274/386 (70%), Positives = 321/386 (83%), Gaps = 16/386 (4%)
Query: 31 AHPMAPPSPSTTSSNNNSSSSSNSGWDQLSKTNLYIRGLPPHTTDQDLVKLCQPYGKIVS 90
A MAPPSPS ++ N++S S+ N DQLSKTNLYIRGL P TTDQDLVKLCQPYGKIVS
Sbjct: 28 AQQMAPPSPSNSTPNSSSGSNGN---DQLSKTNLYIRGLQPGTTDQDLVKLCQPYGKIVS 84
Query: 91 TKAILDKTTNKCKGYGFVDFDSPAAAQKAVSALKASGVQAQMAKQQEQDPTNLYISNLPL 150
TKAILDKTTNKCKGYGFVDFDSP+AAQKAV+ALKASGVQAQMAKQQEQDPTNLYISNLPL
Sbjct: 85 TKAILDKTTNKCKGYGFVDFDSPSAAQKAVTALKASGVQAQMAKQQEQDPTNLYISNLPL 144
Query: 151 SMDEQELENMLKPFGQVISTRILRDSSGTSRGVGFARMESTEKCEAVIGHFNGKFIKTPP 210
SMDEQELE MLKPFGQVISTRILRD+SGTSRGVGFARMESTEKCEA+I HFNGK+IKTPP
Sbjct: 145 SMDEQELEGMLKPFGQVISTRILRDTSGTSRGVGFARMESTEKCEAIITHFNGKYIKTPP 204
Query: 211 GVSAPTEPLLCKFADGGQKKRQNPNKYIPNGRPWHREGEVRLAGMTLTYDPTTAAIQNGF 270
GV AP++PLLCKFADGG KKRQN K++ NGR W R ++ + M LTYDPTT A+QNGF
Sbjct: 205 GVPAPSDPLLCKFADGGPKKRQNQGKFVQNGRAWPRNADMGV--MALTYDPTT-ALQNGF 261
Query: 271 YPSPYSIATNRMITQTSITPYIASPVSAY---------QVQSPSWMQPQPYILQHPGAVL 321
YP+PY+I NRM+ Q++++PY++SPVS+Y QV +PSWM Y++Q G+VL
Sbjct: 262 YPAPYNITPNRMLAQSALSPYLSSPVSSYQRVTQTSPLQVPNPSWMHHHSYLMQPSGSVL 321
Query: 322 TPSMEHTMSLQPASMISPLAQQMSHLSLGSTGTYMPATSAMQGAYLPQYAHMQTTAVPVE 381
TP M+H +SLQPASM+ PL QQ+ HLSL STGTYMP +AMQGAY+ QY + +++V VE
Sbjct: 322 TPGMDHPISLQPASMMGPLTQQLGHLSLSSTGTYMPTAAAMQGAYISQYTPVPSSSVSVE 381
Query: 382 EASGQQ-QVAVETSNDHSPYTFQPNK 406
E+SGQQ QVAV+ ++H Y+FQ NK
Sbjct: 382 ESSGQQNQVAVDAPSEHGVYSFQFNK 407
>gi|115511032 ELAV (embryonic lethal, abnormal vision,
Drosophila)-like 2 (Hu antigen B) [Homo sapiens]
Length = 359
Score = 126 bits (316), Expect = 4e-29
Identities = 80/215 (37%), Positives = 117/215 (54%), Gaps = 23/215 (10%)
Query: 42 TSSNNNSSSSSNSGWDQLSKTNLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNK 101
T+ NNN SS +SG + SKTNL + LP + T ++L L G+I S K + DK T +
Sbjct: 19 TTINNNCSSPVDSGNTEDSKTNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQ 78
Query: 102 CKGYGFVDFDSPAAAQKAVSALKASGVQAQMAKQQEQDPT-------NLYISNLPLSMDE 154
GYGFV++ P A+KA++ L +Q + K P+ NLY+S LP +M +
Sbjct: 79 SLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQ 138
Query: 155 QELENMLKPFGQVISTRILRDS-SGTSRGVGFARMESTEKCEAVIGHFNGKFIKTPPGVS 213
+ELE + +G++I++RIL D +G SRGVGF R + + E I NG + PPG
Sbjct: 139 KELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGLNG---QKPPGA- 194
Query: 214 APTEPLLCKFADGGQKKR---------QNPNKYIP 239
TEP+ KFA+ +K Q+PN+ P
Sbjct: 195 --TEPITVKFANNPSQKTNQAILSQLYQSPNRRYP 227
Score = 45.4 bits (106), Expect = 9e-05
Identities = 24/83 (28%), Positives = 41/83 (49%), Gaps = 6/83 (7%)
Query: 41 TTSSNNNSSSSSNSGWDQLSKTNLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTN 100
T+ + N +GW +++ L P + L ++ P+G + + K I D TN
Sbjct: 261 TSLAGINIPGHPGTGWC------IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTN 314
Query: 101 KCKGYGFVDFDSPAAAQKAVSAL 123
KCKG+GFV + A A+++L
Sbjct: 315 KCKGFGFVTMTNYDEAAMAIASL 337
Score = 38.5 bits (88), Expect = 0.011
Identities = 19/62 (30%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
Query: 143 LYISNLPLSMDEQELENMLKPFGQVISTRILRD-SSGTSRGVGFARMESTEKCEAVIGHF 201
+++ NL DE L M PFG V + +++RD ++ +G GF M + ++ I
Sbjct: 278 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 337
Query: 202 NG 203
NG
Sbjct: 338 NG 339
>gi|221316773 ELAV-like 4 isoform 5 [Homo sapiens]
Length = 369
Score = 117 bits (292), Expect = 2e-26
Identities = 81/248 (32%), Positives = 123/248 (49%), Gaps = 26/248 (10%)
Query: 20 QYLQAKQSLVPAHPMAPPSPSTTSSNNNSSSSSNSG-WDQLSKTNLYIRGLPPHTTDQDL 78
Q + + V P + S +S+N N S +G SKTNL + LP + T ++
Sbjct: 6 QIISTMEPQVSNGPTSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEF 65
Query: 79 VKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPAAAQKAVSALKASGVQAQMAKQQEQ 138
L G+I S K + DK T + GYGFV++ P A+KA++ L +Q + K
Sbjct: 66 RSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYA 125
Query: 139 DPT-------NLYISNLPLSMDEQELENMLKPFGQVISTRILRDS-SGTSRGVGFARMES 190
P+ NLY+S LP +M ++ELE + +G++I++RIL D +G SRGVGF R +
Sbjct: 126 RPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDK 185
Query: 191 TEKCEAVIGHFNGKFIKTPPGVSAPTEPLLCKFADGGQKKR---------QNPNKYIPNG 241
+ E I NG + P G TEP+ KFA+ +K Q+PN+ P
Sbjct: 186 RIEAEEAIKGLNG---QKPSGA---TEPITVKFANNPSQKSSQALLSQLYQSPNRRYPG- 238
Query: 242 RPWHREGE 249
P H + +
Sbjct: 239 -PLHHQAQ 245
Score = 45.4 bits (106), Expect = 9e-05
Identities = 24/77 (31%), Positives = 40/77 (51%), Gaps = 6/77 (7%)
Query: 47 NSSSSSNSGWDQLSKTNLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYG 106
N + +GW +++ L P + + L +L P+G + + K I D TNKCKG+G
Sbjct: 277 NIPGHTGTGWC------IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFG 330
Query: 107 FVDFDSPAAAQKAVSAL 123
FV + A A+++L
Sbjct: 331 FVTMTNYDEAAMAIASL 347
Score = 37.0 bits (84), Expect = 0.032
Identities = 18/62 (29%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
Query: 143 LYISNLPLSMDEQELENMLKPFGQVISTRILRD-SSGTSRGVGFARMESTEKCEAVIGHF 201
+++ NL DE L + PFG V + +++RD ++ +G GF M + ++ I
Sbjct: 288 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 347
Query: 202 NG 203
NG
Sbjct: 348 NG 349
>gi|221316771 ELAV-like 4 isoform 4 [Homo sapiens]
Length = 366
Score = 117 bits (292), Expect = 2e-26
Identities = 80/249 (32%), Positives = 123/249 (49%), Gaps = 32/249 (12%)
Query: 25 KQSLVPAHPMAPPSPSTTSSNNNSSSSSN-------SGWDQLSKTNLYIRGLPPHTTDQD 77
+Q + P P++ +SN SS++ N SKTNL + LP + T ++
Sbjct: 2 EQIISTMEPQVSNGPTSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEE 61
Query: 78 LVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPAAAQKAVSALKASGVQAQMAKQQE 137
L G+I S K + DK T + GYGFV++ P A+KA++ L +Q + K
Sbjct: 62 FRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSY 121
Query: 138 QDPT-------NLYISNLPLSMDEQELENMLKPFGQVISTRILRDS-SGTSRGVGFARME 189
P+ NLY+S LP +M ++ELE + +G++I++RIL D +G SRGVGF R +
Sbjct: 122 ARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFD 181
Query: 190 STEKCEAVIGHFNGKFIKTPPGVSAPTEPLLCKFADGGQKKR---------QNPNKYIPN 240
+ E I NG + P G TEP+ KFA+ +K Q+PN+ P
Sbjct: 182 KRIEAEEAIKGLNG---QKPSGA---TEPITVKFANNPSQKSSQALLSQLYQSPNRRYPG 235
Query: 241 GRPWHREGE 249
P H + +
Sbjct: 236 --PLHHQAQ 242
Score = 45.4 bits (106), Expect = 9e-05
Identities = 24/77 (31%), Positives = 40/77 (51%), Gaps = 6/77 (7%)
Query: 47 NSSSSSNSGWDQLSKTNLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYG 106
N + +GW +++ L P + + L +L P+G + + K I D TNKCKG+G
Sbjct: 274 NIPGHTGTGWC------IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFG 327
Query: 107 FVDFDSPAAAQKAVSAL 123
FV + A A+++L
Sbjct: 328 FVTMTNYDEAAMAIASL 344
Score = 37.0 bits (84), Expect = 0.032
Identities = 18/62 (29%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
Query: 143 LYISNLPLSMDEQELENMLKPFGQVISTRILRD-SSGTSRGVGFARMESTEKCEAVIGHF 201
+++ NL DE L + PFG V + +++RD ++ +G GF M + ++ I
Sbjct: 285 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 344
Query: 202 NG 203
NG
Sbjct: 345 NG 346
>gi|221316765 ELAV-like 4 isoform 1 [Homo sapiens]
Length = 380
Score = 116 bits (290), Expect = 4e-26
Identities = 79/241 (32%), Positives = 120/241 (49%), Gaps = 32/241 (13%)
Query: 33 PMAPPSPSTTSSNNNSSSSSN-------SGWDQLSKTNLYIRGLPPHTTDQDLVKLCQPY 85
P P++ +SN SS++ N SKTNL + LP + T ++ L
Sbjct: 10 PQVSNGPTSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLFGSI 69
Query: 86 GKIVSTKAILDKTTNKCKGYGFVDFDSPAAAQKAVSALKASGVQAQMAKQQEQDPT---- 141
G+I S K + DK T + GYGFV++ P A+KA++ L +Q + K P+
Sbjct: 70 GEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASI 129
Query: 142 ---NLYISNLPLSMDEQELENMLKPFGQVISTRILRDS-SGTSRGVGFARMESTEKCEAV 197
NLY+S LP +M ++ELE + +G++I++RIL D +G SRGVGF R + + E
Sbjct: 130 RDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEA 189
Query: 198 IGHFNGKFIKTPPGVSAPTEPLLCKFADGGQKKR---------QNPNKYIPNGRPWHREG 248
I NG + P G TEP+ KFA+ +K Q+PN+ P P H +
Sbjct: 190 IKGLNG---QKPSGA---TEPITVKFANNPSQKSSQALLSQLYQSPNRRYPG--PLHHQA 241
Query: 249 E 249
+
Sbjct: 242 Q 242
Score = 45.4 bits (106), Expect = 9e-05
Identities = 24/77 (31%), Positives = 40/77 (51%), Gaps = 6/77 (7%)
Query: 47 NSSSSSNSGWDQLSKTNLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYG 106
N + +GW +++ L P + + L +L P+G + + K I D TNKCKG+G
Sbjct: 288 NIPGHTGTGWC------IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFG 341
Query: 107 FVDFDSPAAAQKAVSAL 123
FV + A A+++L
Sbjct: 342 FVTMTNYDEAAMAIASL 358
Score = 37.0 bits (84), Expect = 0.032
Identities = 18/62 (29%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
Query: 143 LYISNLPLSMDEQELENMLKPFGQVISTRILRD-SSGTSRGVGFARMESTEKCEAVIGHF 201
+++ NL DE L + PFG V + +++RD ++ +G GF M + ++ I
Sbjct: 299 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 358
Query: 202 NG 203
NG
Sbjct: 359 NG 360
>gi|221316769 ELAV-like 4 isoform 3 [Homo sapiens]
Length = 383
Score = 116 bits (290), Expect = 4e-26
Identities = 79/241 (32%), Positives = 120/241 (49%), Gaps = 32/241 (13%)
Query: 33 PMAPPSPSTTSSNNNSSSSSN-------SGWDQLSKTNLYIRGLPPHTTDQDLVKLCQPY 85
P P++ +SN SS++ N SKTNL + LP + T ++ L
Sbjct: 27 PQVSNGPTSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLFGSI 86
Query: 86 GKIVSTKAILDKTTNKCKGYGFVDFDSPAAAQKAVSALKASGVQAQMAKQQEQDPT---- 141
G+I S K + DK T + GYGFV++ P A+KA++ L +Q + K P+
Sbjct: 87 GEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASI 146
Query: 142 ---NLYISNLPLSMDEQELENMLKPFGQVISTRILRDS-SGTSRGVGFARMESTEKCEAV 197
NLY+S LP +M ++ELE + +G++I++RIL D +G SRGVGF R + + E
Sbjct: 147 RDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEA 206
Query: 198 IGHFNGKFIKTPPGVSAPTEPLLCKFADGGQKKR---------QNPNKYIPNGRPWHREG 248
I NG + P G TEP+ KFA+ +K Q+PN+ P P H +
Sbjct: 207 IKGLNG---QKPSGA---TEPITVKFANNPSQKSSQALLSQLYQSPNRRYPG--PLHHQA 258
Query: 249 E 249
+
Sbjct: 259 Q 259
Score = 45.4 bits (106), Expect = 9e-05
Identities = 24/77 (31%), Positives = 40/77 (51%), Gaps = 6/77 (7%)
Query: 47 NSSSSSNSGWDQLSKTNLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYG 106
N + +GW +++ L P + + L +L P+G + + K I D TNKCKG+G
Sbjct: 291 NIPGHTGTGWC------IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFG 344
Query: 107 FVDFDSPAAAQKAVSAL 123
FV + A A+++L
Sbjct: 345 FVTMTNYDEAAMAIASL 361
Score = 37.0 bits (84), Expect = 0.032
Identities = 18/62 (29%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
Query: 143 LYISNLPLSMDEQELENMLKPFGQVISTRILRD-SSGTSRGVGFARMESTEKCEAVIGHF 201
+++ NL DE L + PFG V + +++RD ++ +G GF M + ++ I
Sbjct: 302 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 361
Query: 202 NG 203
NG
Sbjct: 362 NG 363
>gi|221316767 ELAV-like 4 isoform 2 [Homo sapiens]
Length = 366
Score = 116 bits (290), Expect = 4e-26
Identities = 79/241 (32%), Positives = 120/241 (49%), Gaps = 32/241 (13%)
Query: 33 PMAPPSPSTTSSNNNSSSSSN-------SGWDQLSKTNLYIRGLPPHTTDQDLVKLCQPY 85
P P++ +SN SS++ N SKTNL + LP + T ++ L
Sbjct: 10 PQVSNGPTSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLFGSI 69
Query: 86 GKIVSTKAILDKTTNKCKGYGFVDFDSPAAAQKAVSALKASGVQAQMAKQQEQDPT---- 141
G+I S K + DK T + GYGFV++ P A+KA++ L +Q + K P+
Sbjct: 70 GEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASI 129
Query: 142 ---NLYISNLPLSMDEQELENMLKPFGQVISTRILRDS-SGTSRGVGFARMESTEKCEAV 197
NLY+S LP +M ++ELE + +G++I++RIL D +G SRGVGF R + + E
Sbjct: 130 RDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEA 189
Query: 198 IGHFNGKFIKTPPGVSAPTEPLLCKFADGGQKKR---------QNPNKYIPNGRPWHREG 248
I NG + P G TEP+ KFA+ +K Q+PN+ P P H +
Sbjct: 190 IKGLNG---QKPSGA---TEPITVKFANNPSQKSSQALLSQLYQSPNRRYPG--PLHHQA 241
Query: 249 E 249
+
Sbjct: 242 Q 242
Score = 45.4 bits (106), Expect = 9e-05
Identities = 24/77 (31%), Positives = 40/77 (51%), Gaps = 6/77 (7%)
Query: 47 NSSSSSNSGWDQLSKTNLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYG 106
N + +GW +++ L P + + L +L P+G + + K I D TNKCKG+G
Sbjct: 274 NIPGHTGTGWC------IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFG 327
Query: 107 FVDFDSPAAAQKAVSAL 123
FV + A A+++L
Sbjct: 328 FVTMTNYDEAAMAIASL 344
Score = 37.0 bits (84), Expect = 0.032
Identities = 18/62 (29%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
Query: 143 LYISNLPLSMDEQELENMLKPFGQVISTRILRD-SSGTSRGVGFARMESTEKCEAVIGHF 201
+++ NL DE L + PFG V + +++RD ++ +G GF M + ++ I
Sbjct: 285 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 344
Query: 202 NG 203
NG
Sbjct: 345 NG 346
>gi|49355761 ELAV-like protein 3 isoform 1 [Homo sapiens]
Length = 367
Score = 110 bits (274), Expect = 3e-24
Identities = 73/219 (33%), Positives = 108/219 (49%), Gaps = 21/219 (9%)
Query: 20 QYLQAKQSLVPAHPMAPPSPSTTSSNNNSSSSSNSGWDQLSKTNLYIRGLPPHTTDQDLV 79
Q L A +S V P P P+ N ++ SKTNL + LP + T +
Sbjct: 4 QILGAMESQVGGGPAGPALPNGPLLGTNGATDD-------SKTNLIVNYLPQNMTQDEFK 56
Query: 80 KLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPAAAQKAVSALKASGVQAQMAKQQEQD 139
L G I S K + DK T + GYGFV++ P A KA++ L +Q + K
Sbjct: 57 SLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINTLNGLKLQTKTIKVSYAR 116
Query: 140 PT-------NLYISNLPLSMDEQELENMLKPFGQVISTRILRDS-SGTSRGVGFARMEST 191
P+ NLY+S LP +M ++E+E + +G++I++RIL D +G SRGVGF R +
Sbjct: 117 PSSASIRDANLYVSGLPKTMSQKEMEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKR 176
Query: 192 EKCEAVIGHFNGKFIKTPPGVSAPTEPLLCKFADGGQKK 230
+ E I NG + P G + EP+ KFA+ +K
Sbjct: 177 IEAEEAIKGLNG---QKPLGAA---EPITVKFANNPSQK 209
Score = 50.4 bits (119), Expect = 3e-06
Identities = 28/91 (30%), Positives = 46/91 (50%), Gaps = 6/91 (6%)
Query: 33 PMAPPSPSTTSSNNNSSSSSNSGWDQLSKTNLYIRGLPPHTTDQDLVKLCQPYGKIVSTK 92
P+A S + S ++ +GW +++ L P + L +L P+G + + K
Sbjct: 261 PIAIDGMSGLAGVGLSGGAAGAGWC------IFVYNLSPEADESVLWQLFGPFGAVTNVK 314
Query: 93 AILDKTTNKCKGYGFVDFDSPAAAQKAVSAL 123
I D TTNKCKG+GFV + A A+++L
Sbjct: 315 VIRDFTTNKCKGFGFVTMTNYDEAAMAIASL 345
Score = 37.7 bits (86), Expect = 0.019
Identities = 18/62 (29%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
Query: 143 LYISNLPLSMDEQELENMLKPFGQVISTRILRD-SSGTSRGVGFARMESTEKCEAVIGHF 201
+++ NL DE L + PFG V + +++RD ++ +G GF M + ++ I
Sbjct: 286 IFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASL 345
Query: 202 NG 203
NG
Sbjct: 346 NG 347
>gi|49355765 ELAV-like protein 3 isoform 2 [Homo sapiens]
Length = 360
Score = 110 bits (274), Expect = 3e-24
Identities = 73/219 (33%), Positives = 108/219 (49%), Gaps = 21/219 (9%)
Query: 20 QYLQAKQSLVPAHPMAPPSPSTTSSNNNSSSSSNSGWDQLSKTNLYIRGLPPHTTDQDLV 79
Q L A +S V P P P+ N ++ SKTNL + LP + T +
Sbjct: 4 QILGAMESQVGGGPAGPALPNGPLLGTNGATDD-------SKTNLIVNYLPQNMTQDEFK 56
Query: 80 KLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPAAAQKAVSALKASGVQAQMAKQQEQD 139
L G I S K + DK T + GYGFV++ P A KA++ L +Q + K
Sbjct: 57 SLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINTLNGLKLQTKTIKVSYAR 116
Query: 140 PT-------NLYISNLPLSMDEQELENMLKPFGQVISTRILRDS-SGTSRGVGFARMEST 191
P+ NLY+S LP +M ++E+E + +G++I++RIL D +G SRGVGF R +
Sbjct: 117 PSSASIRDANLYVSGLPKTMSQKEMEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKR 176
Query: 192 EKCEAVIGHFNGKFIKTPPGVSAPTEPLLCKFADGGQKK 230
+ E I NG + P G + EP+ KFA+ +K
Sbjct: 177 IEAEEAIKGLNG---QKPLGAA---EPITVKFANNPSQK 209
Score = 50.4 bits (119), Expect = 3e-06
Identities = 28/91 (30%), Positives = 46/91 (50%), Gaps = 6/91 (6%)
Query: 33 PMAPPSPSTTSSNNNSSSSSNSGWDQLSKTNLYIRGLPPHTTDQDLVKLCQPYGKIVSTK 92
P+A S + S ++ +GW +++ L P + L +L P+G + + K
Sbjct: 254 PIAIDGMSGLAGVGLSGGAAGAGWC------IFVYNLSPEADESVLWQLFGPFGAVTNVK 307
Query: 93 AILDKTTNKCKGYGFVDFDSPAAAQKAVSAL 123
I D TTNKCKG+GFV + A A+++L
Sbjct: 308 VIRDFTTNKCKGFGFVTMTNYDEAAMAIASL 338
Score = 37.7 bits (86), Expect = 0.019
Identities = 18/62 (29%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
Query: 143 LYISNLPLSMDEQELENMLKPFGQVISTRILRD-SSGTSRGVGFARMESTEKCEAVIGHF 201
+++ NL DE L + PFG V + +++RD ++ +G GF M + ++ I
Sbjct: 279 IFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASL 338
Query: 202 NG 203
NG
Sbjct: 339 NG 340
>gi|38201714 ELAV-like 1 [Homo sapiens]
Length = 326
Score = 103 bits (258), Expect = 2e-22
Identities = 65/186 (34%), Positives = 100/186 (53%), Gaps = 21/186 (11%)
Query: 59 LSKTNLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPAAAQK 118
+ +TNL + LP + T +L L G++ S K I DK GYGFV++ + A++
Sbjct: 17 IGRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAER 76
Query: 119 AVSALKASGVQAQMAKQQEQDPT-------NLYISNLPLSMDEQELENMLKPFGQVISTR 171
A++ L +Q++ K P+ NLYIS LP +M ++++E+M FG++I++R
Sbjct: 77 AINTLNGLRLQSKTIKVSYARPSSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINSR 136
Query: 172 ILRD-SSGTSRGVGFARMESTEKCEAVIGHFNGKFIKTPPGVSAPTEPLLCKFADGGQKK 230
+L D ++G SRGV F R + + E I FNG PPG S EP+ KFA
Sbjct: 137 VLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNG---HKPPGSS---EPITVKFA------ 184
Query: 231 RQNPNK 236
NPN+
Sbjct: 185 -ANPNQ 189
Score = 44.7 bits (104), Expect = 2e-04
Identities = 25/80 (31%), Positives = 41/80 (51%), Gaps = 6/80 (7%)
Query: 44 SNNNSSSSSNSGWDQLSKTNLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCK 103
S N +++SGW ++I L + L ++ P+G + + K I D TNKCK
Sbjct: 232 SGVNVPGNASSGWC------IFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCK 285
Query: 104 GYGFVDFDSPAAAQKAVSAL 123
G+GFV + A A+++L
Sbjct: 286 GFGFVTMTNYEEAAMAIASL 305
Score = 39.3 bits (90), Expect = 0.006
Identities = 21/62 (33%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
Query: 143 LYISNLPLSMDEQELENMLKPFGQVISTRILRD-SSGTSRGVGFARMESTEKCEAVIGHF 201
++I NL DE L M PFG V + +++RD ++ +G GF M + E+ I
Sbjct: 246 IFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASL 305
Query: 202 NG 203
NG
Sbjct: 306 NG 307
>gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens]
Length = 636
Score = 90.5 bits (223), Expect = 2e-18
Identities = 91/374 (24%), Positives = 151/374 (40%), Gaps = 64/374 (17%)
Query: 62 TNLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPAAAQKAVS 121
TN+YI+ D+ L L +G +S K + D++ K KG+GFV F+ AQKAV
Sbjct: 191 TNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDES-GKSKGFGFVSFERHEDAQKAVD 249
Query: 122 ALKASGVQAQMA-------------------KQQEQDP------TNLYISNLPLSMDEQE 156
+ + + +Q +QD NLY+ NL +D++
Sbjct: 250 EMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKNLDDGIDDER 309
Query: 157 LENMLKPFGQVISTRILRDSSGTSRGVGFARMESTEKCEAVIGHFNGKFIKTPPGVSAPT 216
L PFG + S +++ + G S+G GF S E+ + NG+ + T
Sbjct: 310 LRKEFSPFGTITSAKVMME-GGRSKGFGFVCFSSPEEATKAVTEMNGRIV--------AT 360
Query: 217 EPLLCKFADGGQKKRQN-PNKYIPNGRPWHREGEVRLAGMTLTYDPTTAAIQNGFYPSPY 275
+PL A ++++ + N+Y+ R+A + +P + N + P+P
Sbjct: 361 KPLYVALAQRKEERQAHLTNQYMQ-----------RMASVRAVPNP----VINPYQPAPP 405
Query: 276 SIATNRMITQTSITPYIASPVSAYQVQ-SPSW----MQPQPYILQHPGAVLTPSMEHTMS 330
S I QT P Q++ SP W +P P+ PGA+ + S
Sbjct: 406 SGYFMAAIPQTQNRAAYYPPSQIAQLRPSPRWTAQGARPHPF-QNMPGAIRPAAPRPPFS 464
Query: 331 -LQPASMISPLAQQMSHLSLGSTGTYMPATSAMQGA------YLPQYAHMQTTAVPVEEA 383
++PAS P ++ ST T P +A A +PQY + P +
Sbjct: 465 TMRPASSQVPRVMSTQRVANTSTQTMGPRPAAAAAAATPAVRTVPQYKYAAGVRNPQQHL 524
Query: 384 SGQQQVAVETSNDH 397
+ Q QV ++ H
Sbjct: 525 NAQPQVTMQQPAVH 538
Score = 80.1 bits (196), Expect = 3e-15
Identities = 50/187 (26%), Positives = 90/187 (48%), Gaps = 10/187 (5%)
Query: 63 NLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPAAAQKAVSA 122
+LY+ L P T+ L + P G I+S + D T + GY +V+F PA A++A+
Sbjct: 12 SLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
Query: 123 LKASGVQAQMAK--QQEQDPT-------NLYISNLPLSMDEQELENMLKPFGQVISTRIL 173
+ ++ + + ++DP+ N++I NL S+D + L + FG ++S +++
Sbjct: 72 MNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
Query: 174 RDSSGTSRGVGFARMESTEKCEAVIGHFNGKFIKTPPGVSAPTEPLLCKFADGGQKKRQN 233
D +G S+G GF E+ E E I NG + + + A+ G + ++
Sbjct: 132 CDENG-SKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKEREAELGARAKEF 190
Query: 234 PNKYIPN 240
N YI N
Sbjct: 191 TNVYIKN 197
Score = 79.7 bits (195), Expect = 4e-15
Identities = 46/157 (29%), Positives = 80/157 (50%), Gaps = 17/157 (10%)
Query: 63 NLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPAAAQKAVSA 122
N++I+ L ++ L +G I+S K + D+ N KGYGFV F++ AA++A+
Sbjct: 100 NIFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYGFVHFETQEAAERAIEK 157
Query: 123 L--------KASGVQAQMAKQQE-------QDPTNLYISNLPLSMDEQELENMLKPFGQV 167
+ K + + K++E ++ TN+YI N MD++ L+++ FG
Sbjct: 158 MNGMLLNDRKVFVGRFKSRKEREAELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPA 217
Query: 168 ISTRILRDSSGTSRGVGFARMESTEKCEAVIGHFNGK 204
+S +++ D SG S+G GF E E + + NGK
Sbjct: 218 LSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMNGK 254
>gi|185135971 poly(A)-binding protein, cytoplasmic 1-like [Homo
sapiens]
Length = 614
Score = 86.3 bits (212), Expect = 5e-17
Identities = 46/157 (29%), Positives = 85/157 (54%), Gaps = 17/157 (10%)
Query: 63 NLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPAAAQKAVSA 122
N++I+ L ++ L +G I+S K D+ + +G+GFV F++ AAQ+A++
Sbjct: 100 NIFIKNLEDSIDNKALYDTFSTFGNILSCKVACDE--HGSRGFGFVHFETHEAAQQAINT 157
Query: 123 LKASGVQ------AQMAKQQEQDP---------TNLYISNLPLSMDEQELENMLKPFGQV 167
+ + ++E++ TN+Y+ NLP+ +DEQ L+++ FG++
Sbjct: 158 MNGMLLNDRKVFVGHFKSRREREAELGARALEFTNIYVKNLPVDVDEQGLQDLFSQFGKM 217
Query: 168 ISTRILRDSSGTSRGVGFARMESTEKCEAVIGHFNGK 204
+S +++RD+SG SR GF E E+ + + H NGK
Sbjct: 218 LSVKVMRDNSGHSRCFGFVNFEKHEEAQKAVVHMNGK 254
Score = 77.8 bits (190), Expect = 2e-14
Identities = 49/177 (27%), Positives = 83/177 (46%), Gaps = 27/177 (15%)
Query: 59 LSKTNLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPAAAQK 118
L TN+Y++ LP +Q L L +GK++S K + D + + + +GFV+F+ AQK
Sbjct: 188 LEFTNIYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRDNSGHS-RCFGFVNFEKHEEAQK 246
Query: 119 AVSALKASGVQAQMA-------------------KQQEQD------PTNLYISNLPLSMD 153
AV + V ++ +Q +QD NLY+ NL S+D
Sbjct: 247 AVVHMNGKEVSGRLLYAGRAQKRVERQNELKRRFEQMKQDRLRRYQGVNLYVKNLDDSID 306
Query: 154 EQELENMLKPFGQVISTRILRDSSGTSRGVGFARMESTEKCEAVIGHFNGKFIKTPP 210
+ +L P+G + S +++ + G S+G GF S E+ + NG+ + T P
Sbjct: 307 DDKLRKEFSPYGVITSAKVMTE-GGHSKGFGFVCFSSPEEATKAVTEMNGRIVGTKP 362
Score = 75.9 bits (185), Expect = 6e-14
Identities = 48/166 (28%), Positives = 81/166 (48%), Gaps = 13/166 (7%)
Query: 50 SSSNSGWDQLSKTNLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVD 109
++S SG+ S LY+ L P T+ L + P G I+S + D T + GY +++
Sbjct: 2 NASGSGYPLAS---LYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYIN 58
Query: 110 FDSPAAAQKAVSALKASGVQAQMAK--QQEQDP-------TNLYISNLPLSMDEQELENM 160
F PA A++A+ + ++ Q + ++DP N++I NL S+D + L +
Sbjct: 59 FQQPADAERALDTMNFEMLKGQPIRIMWSQRDPGLRKSGVGNIFIKNLEDSIDNKALYDT 118
Query: 161 LKPFGQVISTRILRDSSGTSRGVGFARMESTEKCEAVIGHFNGKFI 206
FG ++S ++ D G SRG GF E+ E + I NG +
Sbjct: 119 FSTFGNILSCKVACDEHG-SRGFGFVHFETHEAAQQAINTMNGMLL 163
>gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens]
Length = 631
Score = 80.9 bits (198), Expect = 2e-15
Identities = 84/366 (22%), Positives = 145/366 (39%), Gaps = 65/366 (17%)
Query: 63 NLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPAAAQKAVSA 122
N+YI+ D+ L L +G +S K + D++ K KG+GFV F+ AQKAV
Sbjct: 192 NVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDES-GKSKGFGFVSFERHEDAQKAVDE 250
Query: 123 LKASGVQAQMA-------------------KQQEQDP------TNLYISNLPLSMDEQEL 157
+ + + +Q +QD NLY+ NL +D++ L
Sbjct: 251 MNGKELNGKQIYVGRAQKKVERQTELKRTFEQMKQDRITRYQVVNLYVKNLDDGIDDERL 310
Query: 158 ENMLKPFGQVISTRILRDSSGTSRGVGFARMESTEKCEAVIGHFNGKFIKTPPGVSAPTE 217
PFG + S +++ + G S+G GF S E+ + NG+ + T+
Sbjct: 311 RKAFSPFGTITSAKVMME-GGRSKGFGFVCFSSPEEATKAVTEMNGRIV--------ATK 361
Query: 218 PLLCKFADGGQKKRQNPNKYIPNGRPWHREGEVRLAGMTLTYDPTTAAIQNGFYPSPYSI 277
PL A ++++ Y+ N E R+A + P A +G++
Sbjct: 362 PLYVALA----QRKEERQAYLTN------EYMQRMASVRAV--PNQRAPPSGYF------ 403
Query: 278 ATNRMITQTSITPYIASPVSAYQVQSPSW--MQPQPYILQHPGAVLTPSMEHT--MSLQP 333
T TQ Y S ++ + SP W +P+ Q+ + + P +++P
Sbjct: 404 MTAVPQTQNHAAYYPPSQIARLR-PSPRWTAQGARPHPFQNKPSAIRPGAPRVPFSTMRP 462
Query: 334 ASMISPLAQQMSHLSLGSTGTYMPATSAMQGA-------YLPQYAHMQTTAVPVEEASGQ 386
AS P ++ ST T P +A A +P+Y + P + + Q
Sbjct: 463 ASSQVPRVMSTQRVANTSTQTVGPRPAAAAAAAATPAVRTVPRYKYAAGVRNPQQHRNAQ 522
Query: 387 QQVAVE 392
QV ++
Sbjct: 523 PQVTMQ 528
Score = 77.0 bits (188), Expect = 3e-14
Identities = 42/158 (26%), Positives = 78/158 (49%), Gaps = 19/158 (12%)
Query: 63 NLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPAAAQKAVSA 122
N++++ L ++ L +G I+S + D+ N KGYGFV F++ AA++A+
Sbjct: 100 NIFVKNLDKSINNKALYDTVSAFGNILSCNVVCDE--NGSKGYGFVHFETHEAAERAIKK 157
Query: 123 LKASGV----------------QAQMAKQQEQDPTNLYISNLPLSMDEQELENMLKPFGQ 166
+ + +A++ + ++ P N+YI N MD++ L+++ FG
Sbjct: 158 MNGMLLNGRKVFVGQFKSRKEREAELGARAKEFP-NVYIKNFGEDMDDERLKDLFGKFGP 216
Query: 167 VISTRILRDSSGTSRGVGFARMESTEKCEAVIGHFNGK 204
+S +++ D SG S+G GF E E + + NGK
Sbjct: 217 ALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMNGK 254
Score = 70.1 bits (170), Expect = 3e-12
Identities = 46/187 (24%), Positives = 87/187 (46%), Gaps = 10/187 (5%)
Query: 63 NLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPAAAQKAVSA 122
+LY+ L P T+ L + P G I+S + D T+ Y +V+F A+ A+
Sbjct: 12 SLYVGDLHPDVTEAMLYEKFSPAGPILSIRICRDLITSGSSNYAYVNFQHTKDAEHALDT 71
Query: 123 LKASGVQAQMAK--QQEQDPT-------NLYISNLPLSMDEQELENMLKPFGQVISTRIL 173
+ ++ + + ++DP+ N+++ NL S++ + L + + FG ++S ++
Sbjct: 72 MNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFVKNLDKSINNKALYDTVSAFGNILSCNVV 131
Query: 174 RDSSGTSRGVGFARMESTEKCEAVIGHFNGKFIKTPPGVSAPTEPLLCKFADGGQKKRQN 233
D +G S+G GF E+ E E I NG + + + A+ G + ++
Sbjct: 132 CDENG-SKGYGFVHFETHEAAERAIKKMNGMLLNGRKVFVGQFKSRKEREAELGARAKEF 190
Query: 234 PNKYIPN 240
PN YI N
Sbjct: 191 PNVYIKN 197
>gi|24762232 bruno-like 5, RNA binding protein isoform 1 [Homo
sapiens]
Length = 485
Score = 79.0 bits (193), Expect = 7e-15
Identities = 84/354 (23%), Positives = 139/354 (39%), Gaps = 74/354 (20%)
Query: 37 PSPSTTSSNNNSSSSSNSGWDQLSKTNLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILD 96
PSP SS G L L++ +P H ++DL L + +G+I + D
Sbjct: 21 PSP-VGSSGPEPPGGQPDGMKDLDAIKLFVGQIPRHLDEKDLKPLFEQFGRIYELTVLKD 79
Query: 97 KTTNKCKGYGFVDFDSPAAAQKAVSALKASGVQAQMAKQQEQDPTN----------LYIS 146
T KG F+ + + +A KA +AL MA+ + P + L++
Sbjct: 80 PYTGMHKGCAFLTYCARDSAIKAQTALHEQKTLPGMARPIQVKPADSESRGGRDRKLFVG 139
Query: 147 NLPLSMDEQELENMLKPFGQVISTRILRDSSGTSRGVGFARMESTEKCEAVIGHFNGKFI 206
L E+++ + +PFG + +LR G+S+G F + S + +A I +G
Sbjct: 140 MLNKQQSEEDVLRLFQPFGVIDECTVLRGPDGSSKGCAFVKFSSHTEAQAAIHALHGS-- 197
Query: 207 KTPPGVSAPTEPLLCKFADGGQKKRQNPNKYIPNGRPWHREGEVRLAGMTLTYDPTTAAI 266
+T PG S+ L+ KFAD +++ T +
Sbjct: 198 QTMPGASS---SLVVKFADTDKER-------------------------------TLRRM 223
Query: 267 QNGFYPSPYSIATNRMITQTSI-TPYIASPVSAYQVQSPSWMQPQPYILQHPGAVLTPSM 325
Q +M+ Q I TP + P S Y + + MQ Q +L G+ L+P
Sbjct: 224 Q-------------QMVGQLGILTPSLTLPFSPYSAYAQALMQQQTTVLSTSGSYLSPG- 269
Query: 326 EHTMSLQPASMISPLAQQMSHLSLGSTGTYMPATSAMQGAYLPQYAHMQTTAVP 379
++ P + QQ+ +SL +PAT + L + TTAVP
Sbjct: 270 ---VAFSPCHI-----QQIGAVSLNG----LPATPIAPASGLHSPPLLGTTAVP 311
Score = 64.7 bits (156), Expect = 1e-10
Identities = 30/78 (38%), Positives = 48/78 (61%)
Query: 63 NLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPAAAQKAVSA 122
NL+I LP D +L ++ P+G I+S+K +D+ TN+ K +GFV FD+PA+AQ A+ A
Sbjct: 401 NLFIYHLPQEFGDTELTQMFLPFGNIISSKVFMDRATNQSKCFGFVSFDNPASAQAAIQA 460
Query: 123 LKASGVQAQMAKQQEQDP 140
+ + + K Q + P
Sbjct: 461 MNGFQIGMKRLKVQLKRP 478
Score = 44.7 bits (104), Expect = 2e-04
Identities = 24/75 (32%), Positives = 40/75 (53%), Gaps = 3/75 (4%)
Query: 132 MAKQQEQDPT--NLYISNLPLSMDEQELENMLKPFGQVISTRILRD-SSGTSRGVGFARM 188
+ +QQ + P NL+I +LP + EL M PFG +IS+++ D ++ S+ GF
Sbjct: 389 LQQQQREGPEGCNLFIYHLPQEFGDTELTQMFLPFGNIISSKVFMDRATNQSKCFGFVSF 448
Query: 189 ESTEKCEAVIGHFNG 203
++ +A I NG
Sbjct: 449 DNPASAQAAIQAMNG 463
>gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Homo
sapiens]
Length = 631
Score = 79.0 bits (193), Expect = 7e-15
Identities = 67/273 (24%), Positives = 111/273 (40%), Gaps = 50/273 (18%)
Query: 62 TNLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPAAAQKAVS 121
TN+YI+ D+ L +L +GK +S K + D K KG+GFV ++ A KAV
Sbjct: 191 TNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPN-GKSKGFGFVSYEKHEDANKAVE 249
Query: 122 ALKASGV----------------QAQMAKQQEQ---------DPTNLYISNLPLSMDEQE 156
+ + QA++ ++ EQ NLYI NL ++D+++
Sbjct: 250 EMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEK 309
Query: 157 LENMLKPFGQVISTRILRDSSGTSRGVGFARMESTEKCEAVIGHFNGKFIKTPPGVSAPT 216
L PFG + S +++ + G S+G GF S E+ + NG+ + +
Sbjct: 310 LRKEFSPFGSITSAKVMLE-DGRSKGFGFVCFSSPEEATKAVTEMNGRIV--------GS 360
Query: 217 EPLLCKFADGGQKKRQN-PNKYIPNGRPWHREGEVRLAGMTLTYDPTTAAIQNGFYPSPY 275
+PL A ++++ + N+Y+ R+AGM AI N F P+
Sbjct: 361 KPLYVALAQRKEERKAHLTNQYMQ-----------RVAGMRAL---PANAILNQFQPAAG 406
Query: 276 SIATNRMITQTSITPYIASPVSAYQVQSPSWMQ 308
+ PY A +P W Q
Sbjct: 407 GYFVPAVPQAQGRPPYYTPNQLAQMRPNPRWQQ 439
Score = 77.0 bits (188), Expect = 3e-14
Identities = 46/159 (28%), Positives = 79/159 (49%), Gaps = 17/159 (10%)
Query: 63 NLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPAAAQKAVSA 122
N++I+ L ++ L +G I+S K + D+ N KGY FV F++ AA KA+
Sbjct: 100 NVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYAFVHFETQEAADKAIEK 157
Query: 123 L--------KASGVQAQMAKQQE-------QDPTNLYISNLPLSMDEQELENMLKPFGQV 167
+ K + + K++E ++ TN+YI N +D++ L+ + FG+
Sbjct: 158 MNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKT 217
Query: 168 ISTRILRDSSGTSRGVGFARMESTEKCEAVIGHFNGKFI 206
+S +++RD +G S+G GF E E + NGK I
Sbjct: 218 LSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMNGKEI 256
Score = 73.9 bits (180), Expect = 2e-13
Identities = 48/197 (24%), Positives = 90/197 (45%), Gaps = 10/197 (5%)
Query: 53 NSGWDQLSKTNLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDS 112
N+ +LY+ L T+ L + P G ++S + D T + GY +V+F
Sbjct: 2 NAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQ 61
Query: 113 PAAAQKAVSALKASGVQAQMAK--QQEQDPT-------NLYISNLPLSMDEQELENMLKP 163
PA A++A+ + ++ + + ++DP+ N++I NL S+D + L +
Sbjct: 62 PADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSA 121
Query: 164 FGQVISTRILRDSSGTSRGVGFARMESTEKCEAVIGHFNGKFIKTPPGVSAPTEPLLCKF 223
FG ++S +++ D +G S+G F E+ E + I NG + + +
Sbjct: 122 FGNILSCKVVCDENG-SKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKERE 180
Query: 224 ADGGQKKRQNPNKYIPN 240
A+ G K ++ N YI N
Sbjct: 181 AELGAKAKEFTNVYIKN 197
>gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo
sapiens]
Length = 644
Score = 79.0 bits (193), Expect = 7e-15
Identities = 67/273 (24%), Positives = 111/273 (40%), Gaps = 50/273 (18%)
Query: 62 TNLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPAAAQKAVS 121
TN+YI+ D+ L +L +GK +S K + D K KG+GFV ++ A KAV
Sbjct: 191 TNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPN-GKSKGFGFVSYEKHEDANKAVE 249
Query: 122 ALKASGV----------------QAQMAKQQEQ---------DPTNLYISNLPLSMDEQE 156
+ + QA++ ++ EQ NLYI NL ++D+++
Sbjct: 250 EMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEK 309
Query: 157 LENMLKPFGQVISTRILRDSSGTSRGVGFARMESTEKCEAVIGHFNGKFIKTPPGVSAPT 216
L PFG + S +++ + G S+G GF S E+ + NG+ + +
Sbjct: 310 LRKEFSPFGSITSAKVMLE-DGRSKGFGFVCFSSPEEATKAVTEMNGRIV--------GS 360
Query: 217 EPLLCKFADGGQKKRQN-PNKYIPNGRPWHREGEVRLAGMTLTYDPTTAAIQNGFYPSPY 275
+PL A ++++ + N+Y+ R+AGM AI N F P+
Sbjct: 361 KPLYVALAQRKEERKAHLTNQYMQ-----------RVAGMRAL---PANAILNQFQPAAG 406
Query: 276 SIATNRMITQTSITPYIASPVSAYQVQSPSWMQ 308
+ PY A +P W Q
Sbjct: 407 GYFVPAVPQAQGRPPYYTPNQLAQMRPNPRWQQ 439
Score = 77.0 bits (188), Expect = 3e-14
Identities = 46/159 (28%), Positives = 79/159 (49%), Gaps = 17/159 (10%)
Query: 63 NLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPAAAQKAVSA 122
N++I+ L ++ L +G I+S K + D+ N KGY FV F++ AA KA+
Sbjct: 100 NVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYAFVHFETQEAADKAIEK 157
Query: 123 L--------KASGVQAQMAKQQE-------QDPTNLYISNLPLSMDEQELENMLKPFGQV 167
+ K + + K++E ++ TN+YI N +D++ L+ + FG+
Sbjct: 158 MNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKT 217
Query: 168 ISTRILRDSSGTSRGVGFARMESTEKCEAVIGHFNGKFI 206
+S +++RD +G S+G GF E E + NGK I
Sbjct: 218 LSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMNGKEI 256
Score = 73.9 bits (180), Expect = 2e-13
Identities = 48/197 (24%), Positives = 90/197 (45%), Gaps = 10/197 (5%)
Query: 53 NSGWDQLSKTNLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDS 112
N+ +LY+ L T+ L + P G ++S + D T + GY +V+F
Sbjct: 2 NAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQ 61
Query: 113 PAAAQKAVSALKASGVQAQMAK--QQEQDPT-------NLYISNLPLSMDEQELENMLKP 163
PA A++A+ + ++ + + ++DP+ N++I NL S+D + L +
Sbjct: 62 PADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSA 121
Query: 164 FGQVISTRILRDSSGTSRGVGFARMESTEKCEAVIGHFNGKFIKTPPGVSAPTEPLLCKF 223
FG ++S +++ D +G S+G F E+ E + I NG + + +
Sbjct: 122 FGNILSCKVVCDENG-SKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKERE 180
Query: 224 ADGGQKKRQNPNKYIPN 240
A+ G K ++ N YI N
Sbjct: 181 AELGAKAKEFTNVYIKN 197
>gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Homo
sapiens]
Length = 660
Score = 79.0 bits (193), Expect = 7e-15
Identities = 67/273 (24%), Positives = 111/273 (40%), Gaps = 50/273 (18%)
Query: 62 TNLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPAAAQKAVS 121
TN+YI+ D+ L +L +GK +S K + D K KG+GFV ++ A KAV
Sbjct: 191 TNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPN-GKSKGFGFVSYEKHEDANKAVE 249
Query: 122 ALKASGV----------------QAQMAKQQEQ---------DPTNLYISNLPLSMDEQE 156
+ + QA++ ++ EQ NLYI NL ++D+++
Sbjct: 250 EMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEK 309
Query: 157 LENMLKPFGQVISTRILRDSSGTSRGVGFARMESTEKCEAVIGHFNGKFIKTPPGVSAPT 216
L PFG + S +++ + G S+G GF S E+ + NG+ + +
Sbjct: 310 LRKEFSPFGSITSAKVMLE-DGRSKGFGFVCFSSPEEATKAVTEMNGRIV--------GS 360
Query: 217 EPLLCKFADGGQKKRQN-PNKYIPNGRPWHREGEVRLAGMTLTYDPTTAAIQNGFYPSPY 275
+PL A ++++ + N+Y+ R+AGM AI N F P+
Sbjct: 361 KPLYVALAQRKEERKAHLTNQYMQ-----------RVAGMRAL---PANAILNQFQPAAG 406
Query: 276 SIATNRMITQTSITPYIASPVSAYQVQSPSWMQ 308
+ PY A +P W Q
Sbjct: 407 GYFVPAVPQAQGRPPYYTPNQLAQMRPNPRWQQ 439
Score = 77.0 bits (188), Expect = 3e-14
Identities = 46/159 (28%), Positives = 79/159 (49%), Gaps = 17/159 (10%)
Query: 63 NLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPAAAQKAVSA 122
N++I+ L ++ L +G I+S K + D+ N KGY FV F++ AA KA+
Sbjct: 100 NVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYAFVHFETQEAADKAIEK 157
Query: 123 L--------KASGVQAQMAKQQE-------QDPTNLYISNLPLSMDEQELENMLKPFGQV 167
+ K + + K++E ++ TN+YI N +D++ L+ + FG+
Sbjct: 158 MNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKT 217
Query: 168 ISTRILRDSSGTSRGVGFARMESTEKCEAVIGHFNGKFI 206
+S +++RD +G S+G GF E E + NGK I
Sbjct: 218 LSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMNGKEI 256
Score = 73.9 bits (180), Expect = 2e-13
Identities = 48/197 (24%), Positives = 90/197 (45%), Gaps = 10/197 (5%)
Query: 53 NSGWDQLSKTNLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDS 112
N+ +LY+ L T+ L + P G ++S + D T + GY +V+F
Sbjct: 2 NAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQ 61
Query: 113 PAAAQKAVSALKASGVQAQMAK--QQEQDPT-------NLYISNLPLSMDEQELENMLKP 163
PA A++A+ + ++ + + ++DP+ N++I NL S+D + L +
Sbjct: 62 PADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSA 121
Query: 164 FGQVISTRILRDSSGTSRGVGFARMESTEKCEAVIGHFNGKFIKTPPGVSAPTEPLLCKF 223
FG ++S +++ D +G S+G F E+ E + I NG + + +
Sbjct: 122 FGNILSCKVVCDENG-SKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKERE 180
Query: 224 ADGGQKKRQNPNKYIPN 240
A+ G K ++ N YI N
Sbjct: 181 AELGAKAKEFTNVYIKN 197
>gi|109948285 poly(A) binding protein, cytoplasmic 1-like 2B [Homo
sapiens]
Length = 200
Score = 76.6 bits (187), Expect = 4e-14
Identities = 43/153 (28%), Positives = 76/153 (49%), Gaps = 10/153 (6%)
Query: 63 NLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPAAAQKAVSA 122
+LY+ L P T+ L + P G I+S + DK T + GY +V++ P A++A+
Sbjct: 3 SLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRALET 62
Query: 123 LKASGVQAQMAK--QQEQDPT-------NLYISNLPLSMDEQELENMLKPFGQVISTRIL 173
L ++ + + ++DP+ N++I NL ++D + L N+ FG ++S ++
Sbjct: 63 LNFDVIKGRPVRIMWSQRDPSLRKSGVGNVFIKNLGKTIDNKALYNIFSAFGNILSCKVA 122
Query: 174 RDSSGTSRGVGFARMESTEKCEAVIGHFNGKFI 206
D G +G GF + E E I NG F+
Sbjct: 123 CDEKG-PKGYGFVHFQKQESAERAIDVMNGMFL 154
>gi|61175237 poly(A) binding protein, cytoplasmic 1-like 2A [Homo
sapiens]
Length = 200
Score = 76.6 bits (187), Expect = 4e-14
Identities = 43/153 (28%), Positives = 76/153 (49%), Gaps = 10/153 (6%)
Query: 63 NLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPAAAQKAVSA 122
+LY+ L P T+ L + P G I+S + DK T + GY +V++ P A++A+
Sbjct: 3 SLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRALET 62
Query: 123 LKASGVQAQMAK--QQEQDPT-------NLYISNLPLSMDEQELENMLKPFGQVISTRIL 173
L ++ + + ++DP+ N++I NL ++D + L N+ FG ++S ++
Sbjct: 63 LNFDVIKGRPVRIMWSQRDPSLRKSGVGNVFIKNLGKTIDNKALYNIFSAFGNILSCKVA 122
Query: 174 RDSSGTSRGVGFARMESTEKCEAVIGHFNGKFI 206
D G +G GF + E E I NG F+
Sbjct: 123 CDEKG-PKGYGFVHFQKQESAERAIDVMNGMFL 154
>gi|18201888 poly(A) binding protein, cytoplasmic 5 [Homo sapiens]
Length = 382
Score = 75.9 bits (185), Expect = 6e-14
Identities = 48/169 (28%), Positives = 88/169 (52%), Gaps = 21/169 (12%)
Query: 57 DQLSKT---NLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSP 113
D+L K+ N++I+ L ++ L L +G I+S K + D N KGY +V FDS
Sbjct: 98 DRLRKSGVGNIFIKNLDKSIDNRALFYLFSAFGNILSCKVVCDD--NGSKGYAYVHFDSL 155
Query: 114 AAAQKAV---SALKASGVQ-------------AQMAKQQEQDPTNLYISNLPLSMDEQEL 157
AAA +A+ + ++ + Q A++ + TN+++ N+ +D+++L
Sbjct: 156 AAANRAIWHMNGVRLNNRQVYVGRFKFPEERAAEVRTRDRATFTNVFVKNIGDDIDDEKL 215
Query: 158 ENMLKPFGQVISTRILRDSSGTSRGVGFARMESTEKCEAVIGHFNGKFI 206
+ + +G S +++RD+SG S+G GF R E+ E + + +GK I
Sbjct: 216 KELFCEYGPTESVKVIRDASGKSKGFGFVRYETHEAAQKAVLDLHGKSI 264
Score = 69.3 bits (168), Expect = 6e-12
Identities = 42/152 (27%), Positives = 70/152 (46%), Gaps = 10/152 (6%)
Query: 61 KTNLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPAAAQKAV 120
K LY+ L P T+ L K +P G + T+ D T GYG+V+F PA A+ A+
Sbjct: 17 KAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWAL 76
Query: 121 SALKASGVQAQMAKQQEQDPT---------NLYISNLPLSMDEQELENMLKPFGQVISTR 171
+ + + + + P N++I NL S+D + L + FG ++S +
Sbjct: 77 NTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNLDKSIDNRALFYLFSAFGNILSCK 136
Query: 172 ILRDSSGTSRGVGFARMESTEKCEAVIGHFNG 203
++ D +G S+G + +S I H NG
Sbjct: 137 VVCDDNG-SKGYAYVHFDSLAAANRAIWHMNG 167
Score = 63.2 bits (152), Expect = 4e-10
Identities = 42/179 (23%), Positives = 81/179 (45%), Gaps = 27/179 (15%)
Query: 57 DQLSKTNLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPAAA 116
D+ + TN++++ + D+ L +L YG S K I D + K KG+GFV +++ AA
Sbjct: 194 DRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRD-ASGKSKGFGFVRYETHEAA 252
Query: 117 QKAVSALKASGVQAQM------------------------AKQQEQDP-TNLYISNLPLS 151
QKAV L + ++ K++ + P +YI NL +
Sbjct: 253 QKAVLDLHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPPGVPIYIKNLDET 312
Query: 152 MDEQELENMLKPFGQVISTRILRDSSGTSRGVGFARMESTEKCEAVIGHFNGKFIKTPP 210
+++++L+ FG + +++ + G +G G S E+ + NG+ + + P
Sbjct: 313 INDEKLKEEFSSFGSISRAKVMME-VGQGKGFGVVCFSSFEEATKAVDEMNGRIVGSKP 370
>gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo
sapiens]
Length = 370
Score = 75.1 bits (183), Expect = 1e-13
Identities = 42/159 (26%), Positives = 80/159 (50%), Gaps = 17/159 (10%)
Query: 63 NLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPAAAQKAVSA 122
N++I+ L ++ L + +GKI+S+K + D +K GY FV F + +AA +A+
Sbjct: 99 NVFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSDDQGSK--GYAFVHFQNQSAADRAIEE 156
Query: 123 LKASGVQAQMA---------------KQQEQDPTNLYISNLPLSMDEQELENMLKPFGQV 167
+ ++ + + + TN+YI N MD++ L+++ +G+
Sbjct: 157 MNGKLLKGCKVFVGRFKNRKDREAELRSKASEFTNVYIKNFGGDMDDERLKDVFSKYGKT 216
Query: 168 ISTRILRDSSGTSRGVGFARMESTEKCEAVIGHFNGKFI 206
+S +++ DSSG S+G GF +S E + + NG+ I
Sbjct: 217 LSVKVMTDSSGKSKGFGFVSFDSHEAAKKAVEEMNGRDI 255
Score = 74.3 bits (181), Expect = 2e-13
Identities = 49/174 (28%), Positives = 80/174 (45%), Gaps = 27/174 (15%)
Query: 62 TNLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPAAAQKAVS 121
TN+YI+ D+ L + YGK +S K + D ++ K KG+GFV FDS AA+KAV
Sbjct: 190 TNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTD-SSGKSKGFGFVSFDSHEAAKKAVE 248
Query: 122 ALKASGV----------------QAQMAKQQEQ---------DPTNLYISNLPLSMDEQE 156
+ + QA++ + EQ LYI NL ++D+++
Sbjct: 249 EMNGRDINGQLIFVGRAQKKVERQAELKQMFEQLKRERIRGCQGVKLYIKNLDDTIDDEK 308
Query: 157 LENMLKPFGQVISTRILRDSSGTSRGVGFARMESTEKCEAVIGHFNGKFIKTPP 210
L N FG + +++++ G S+G G S E + NG+ + + P
Sbjct: 309 LRNEFSSFGSISRVKVMQE-EGQSKGFGLICFSSPEDATKAMTEMNGRILGSKP 361
Score = 65.1 bits (157), Expect = 1e-10
Identities = 39/154 (25%), Positives = 74/154 (48%), Gaps = 10/154 (6%)
Query: 63 NLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPAAAQKAVSA 122
+LY+ L T+ L + G ++S + D+ T + GY +V+F A AQKA+
Sbjct: 11 SLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKALDT 70
Query: 123 -----LKASGVQAQMAKQ----QEQDPTNLYISNLPLSMDEQELENMLKPFGQVISTRIL 173
+K ++ +++ + N++I NL S+D + L FG+++S++++
Sbjct: 71 MNFDIIKGKSIRLMWSQRDAYLRRSGIGNVFIKNLDKSIDNKTLYEHFSAFGKILSSKVM 130
Query: 174 RDSSGTSRGVGFARMESTEKCEAVIGHFNGKFIK 207
D G S+G F ++ + I NGK +K
Sbjct: 131 SDDQG-SKGYAFVHFQNQSAADRAIEEMNGKLLK 163
>gi|71164894 trinucleotide repeat containing 4 [Homo sapiens]
Length = 465
Score = 73.2 bits (178), Expect = 4e-13
Identities = 89/370 (24%), Positives = 149/370 (40%), Gaps = 56/370 (15%)
Query: 64 LYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPAAAQKAVSAL 123
L++ +P H ++DL + + +G+I I DK T KG F+ + + +A KA SAL
Sbjct: 9 LFVGQIPRHLEEKDLKPIFEQFGRIFELTVIKDKYTGLHKGCAFLTYCARDSALKAQSAL 68
Query: 124 KASGVQAQMAKQQEQDPTN---------LYISNLPLSMDEQELENMLKPFGQVISTRILR 174
M + + P + L++ L ++++ M +PFG + +LR
Sbjct: 69 HEQKTLPGMNRPIQVKPADSESRGEDRKLFVGMLGKQQTDEDVRKMFEPFGTIDECTVLR 128
Query: 175 DSSGTSRGVGFARMESTEKCEAVIGHFNGKFIKTPPGVSAPTEPLLCKFAD----GGQKK 230
GTS+G F + ++ + +A I + +T PG S+ L+ KFAD G ++
Sbjct: 129 GPDGTSKGCAFVKFQTHAEAQAAINTLHSS--RTLPGASS---SLVVKFADTEKERGLRR 183
Query: 231 RQNP--------------NKYIPNGRPWHREGEVRLAGMTLTYDP--TTAAIQ------- 267
Q Y + ++ +A + P T AA+Q
Sbjct: 184 MQQVATQLGMFSPIALQFGAYSAYTQALMQQQAALVAAHSAYLSPMATMAAVQMQHMAAI 243
Query: 268 --NGFYPSPYSIATNRMITQTSITPYI-ASPVSAYQ----VQSPSWMQPQPYILQHPGAV 320
NG +P + ++ TS P I A+PVSA V S + QP P A+
Sbjct: 244 NANGLIATPITPSSG-----TSTPPAIAATPVSAIPAALGVNGYSPVPTQPTGQPAPDAL 298
Query: 321 LTPSMEHTMSLQPASMISPLAQQMSHLSLGSTGTYMPATSAMQGAY--LPQYAHMQTTAV 378
+ + PA+ + PL Q + + T Y A S + A+ P Q
Sbjct: 299 YPNGVHPYPAQSPAAPVDPLQQAYAGMQ-HYTAAYPAAYSLVAPAFPQPPALVAQQPPPP 357
Query: 379 PVEEASGQQQ 388
P ++ QQQ
Sbjct: 358 PQQQQQQQQQ 367
Score = 71.2 bits (173), Expect = 2e-12
Identities = 39/131 (29%), Positives = 63/131 (48%), Gaps = 4/131 (3%)
Query: 10 YPQYATYYYPQYLQAKQSLVPAHPMAPPSPSTTSSNNNSSSSSNSGWDQLSKTNLYIRGL 69
YP + P + Q +LV P PP G D N++I L
Sbjct: 332 YPAAYSLVAPAFPQPP-ALVAQQPPPPPQQQQQQQQQQQQQQQREGPDGC---NIFIYHL 387
Query: 70 PPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPAAAQKAVSALKASGVQ 129
P TD +++++ P+G ++S K +D+ TN+ K +GFV FD+PA+AQ A+ A+ +
Sbjct: 388 PQEFTDSEILQMFVPFGHVISAKVFVDRATNQSKCFGFVSFDNPASAQAAIQAMNGFQIG 447
Query: 130 AQMAKQQEQDP 140
+ K Q + P
Sbjct: 448 MKRLKVQLKRP 458
Score = 45.1 bits (105), Expect = 1e-04
Identities = 26/80 (32%), Positives = 41/80 (51%), Gaps = 5/80 (6%)
Query: 129 QAQMAKQQEQ----DPTNLYISNLPLSMDEQELENMLKPFGQVISTRILRD-SSGTSRGV 183
Q Q +QQ+Q D N++I +LP + E+ M PFG VIS ++ D ++ S+
Sbjct: 364 QQQQQQQQQQREGPDGCNIFIYHLPQEFTDSEILQMFVPFGHVISAKVFVDRATNQSKCF 423
Query: 184 GFARMESTEKCEAVIGHFNG 203
GF ++ +A I NG
Sbjct: 424 GFVSFDNPASAQAAIQAMNG 443
>gi|187761303 bruno-like 4, RNA binding protein isoform 4 [Homo
sapiens]
Length = 448
Score = 66.6 bits (161), Expect = 4e-11
Identities = 47/176 (26%), Positives = 80/176 (45%), Gaps = 14/176 (7%)
Query: 64 LYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPAAAQKAVSAL 123
L+I +P + ++DL L + +GKI + D+ T KG F+ + +A KA SAL
Sbjct: 56 LFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSAL 115
Query: 124 KASGVQAQMAKQQEQDPTN---------LYISNLPLSMDEQELENMLKPFGQVISTRILR 174
M + + P + L++ L E ++ + + FG + ILR
Sbjct: 116 HEQKTLPGMNRPIQVKPADSESRGEDRKLFVGMLNKQQSEDDVRRLFEAFGNIEECTILR 175
Query: 175 DSSGTSRGVGFARMESTEKCEAVIGHFNGKFIKTPPGVSAPTEPLLCKFADGGQKK 230
G S+G F + S + +A I +G +T PG S+ L+ KFAD +++
Sbjct: 176 GPDGNSKGCAFVKYSSHAEAQAAINALHGS--QTMPGASS---SLVVKFADTDKER 226
Score = 38.9 bits (89), Expect = 0.008
Identities = 22/86 (25%), Positives = 45/86 (52%), Gaps = 9/86 (10%)
Query: 136 QEQDPTNLYISNLPLSMDEQELENMLKPFGQVISTRILRDS-SGTSRGVGF---ARMEST 191
++ D L+I +P ++DE++L+ + + FG++ +L+D +G +G F ES
Sbjct: 49 KDHDAIKLFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESA 108
Query: 192 EKCEAVIGHFNGKFIKTPPGVSAPTE 217
K ++ + KT PG++ P +
Sbjct: 109 LKAQSALHE-----QKTLPGMNRPIQ 129
Score = 30.8 bits (68), Expect = 2.3
Identities = 14/35 (40%), Positives = 21/35 (60%)
Query: 106 GFVDFDSPAAAQKAVSALKASGVQAQMAKQQEQDP 140
GFV FD+PA+AQ A+ A+ + + K Q + P
Sbjct: 407 GFVSFDNPASAQTAIQAMNGFQIGMKRLKVQLKRP 441
>gi|68303647 CUG triplet repeat, RNA binding protein 2 isoform 3
[Homo sapiens]
Length = 508
Score = 64.3 bits (155), Expect = 2e-10
Identities = 50/206 (24%), Positives = 89/206 (43%), Gaps = 18/206 (8%)
Query: 40 STTSSNNNSSSSSNSGWDQLSKTNLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTT 99
S ++N + + +S +++ +P ++++L +L +PYG + + D++
Sbjct: 18 SNGTANKMNGALDHSDQPDPDAIKMFVGQIPRSWSEKELKELFEPYGAVYQINVLRDRSQ 77
Query: 100 N--KCKGYGFVDFDSPAAAQKAVSALK----ASGVQ-------AQMAKQQEQDPTNLYIS 146
N + KG FV F + AA +A +AL G+ A K + L+I
Sbjct: 78 NPPQSKGCCFVTFYTRKAALEAQNALHNIKTLPGMHHPIQMKPADSEKSNAVEDRKLFIG 137
Query: 147 NLPLSMDEQELENMLKPFGQVISTRILRDSSGTSRGVGFARMESTEKCEAVIGHFNGKFI 206
+ +E ++ M PFGQ+ RILR G SRG F + + I K +
Sbjct: 138 MVSKKCNENDIRVMFSPFGQIEECRILRGPDGLSRGCAFVTFSTRAMAQNAI-----KAM 192
Query: 207 KTPPGVSAPTEPLLCKFADGGQKKRQ 232
+ + P++ KFAD + K Q
Sbjct: 193 HQSQTMEGCSSPIVVKFADTQKDKEQ 218
Score = 63.9 bits (154), Expect = 2e-10
Identities = 28/74 (37%), Positives = 45/74 (60%)
Query: 63 NLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPAAAQKAVSA 122
NL+I LP DQD++++ P+G ++S K +DK TN K +GFV +D+P +AQ A+ A
Sbjct: 424 NLFIYHLPQEFGDQDILQMFMPFGNVISAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQA 483
Query: 123 LKASGVQAQMAKQQ 136
+ + + K Q
Sbjct: 484 MNGFQIGMKRLKVQ 497
Score = 42.7 bits (99), Expect = 6e-04
Identities = 25/78 (32%), Positives = 39/78 (50%), Gaps = 3/78 (3%)
Query: 129 QAQMAKQQEQDP--TNLYISNLPLSMDEQELENMLKPFGQVISTRILRD-SSGTSRGVGF 185
Q A Q++ P NL+I +LP +Q++ M PFG VIS ++ D + S+ GF
Sbjct: 409 QQSAAGSQKEGPEGANLFIYHLPQEFGDQDILQMFMPFGNVISAKVFIDKQTNLSKCFGF 468
Query: 186 ARMESTEKCEAVIGHFNG 203
++ +A I NG
Sbjct: 469 VSYDNPVSAQAAIQAMNG 486
>gi|70780381 bruno-like 6, RNA binding protein [Homo sapiens]
Length = 481
Score = 64.3 bits (155), Expect = 2e-10
Identities = 45/176 (25%), Positives = 80/176 (45%), Gaps = 14/176 (7%)
Query: 64 LYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPAAAQKAVSAL 123
L++ +P +QDL L + +G+I + D+ T KG F+ + + +A KA SAL
Sbjct: 48 LFVGQIPRGLDEQDLKPLFEEFGRIYELTVLKDRLTGLHKGCAFLTYCARDSALKAQSAL 107
Query: 124 KASGVQAQMAKQQEQDPT---------NLYISNLPLSMDEQELENMLKPFGQVISTRILR 174
M + + P L++ L E+++ + +PFG + +LR
Sbjct: 108 HEQKTLPGMNRPIQVKPAASEGRGEDRKLFVGMLGKQQGEEDVRRLFQPFGHIEECTVLR 167
Query: 175 DSSGTSRGVGFARMESTEKCEAVIGHFNGKFIKTPPGVSAPTEPLLCKFADGGQKK 230
GTS+G F + S + +A I +G +T G S+ L+ K AD +++
Sbjct: 168 SPDGTSKGCAFVKFGSQGEAQAAIRGLHGS--RTMAGASS---SLVVKLADTDRER 218
Score = 62.0 bits (149), Expect = 9e-10
Identities = 29/78 (37%), Positives = 46/78 (58%)
Query: 63 NLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPAAAQKAVSA 122
NL+I LP D +L++ P+G +VS K +D+ TN+ K +GFV FD+P +AQ A+ A
Sbjct: 397 NLFIYHLPQEFGDAELIQTFLPFGAVVSAKVFVDRATNQSKCFGFVSFDNPTSAQTAIQA 456
Query: 123 LKASGVQAQMAKQQEQDP 140
+ + + K Q + P
Sbjct: 457 MNGFQIGMKRLKVQLKRP 474
Score = 38.5 bits (88), Expect = 0.011
Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
Query: 132 MAKQQEQDPT--NLYISNLPLSMDEQELENMLKPFGQVISTRILRD-SSGTSRGVGFARM 188
+ +QQ + P NL+I +LP + EL PFG V+S ++ D ++ S+ GF
Sbjct: 385 LPQQQREGPEGCNLFIYHLPQEFGDAELIQTFLPFGAVVSAKVFVDRATNQSKCFGFVSF 444
Query: 189 ESTEKCEAVIGHFNG 203
++ + I NG
Sbjct: 445 DNPTSAQTAIQAMNG 459
Score = 38.1 bits (87), Expect = 0.014
Identities = 21/86 (24%), Positives = 44/86 (51%), Gaps = 9/86 (10%)
Query: 136 QEQDPTNLYISNLPLSMDEQELENMLKPFGQVISTRILRDS-SGTSRGVGF---ARMEST 191
++ D L++ +P +DEQ+L+ + + FG++ +L+D +G +G F +S
Sbjct: 41 KDHDAIKLFVGQIPRGLDEQDLKPLFEEFGRIYELTVLKDRLTGLHKGCAFLTYCARDSA 100
Query: 192 EKCEAVIGHFNGKFIKTPPGVSAPTE 217
K ++ + KT PG++ P +
Sbjct: 101 LKAQSALHE-----QKTLPGMNRPIQ 121
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.126 0.374
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,807,224
Number of Sequences: 37866
Number of extensions: 810484
Number of successful extensions: 3636
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 215
Number of HSP's successfully gapped in prelim test: 84
Number of HSP's that attempted gapping in prelim test: 2780
Number of HSP's gapped (non-prelim): 675
length of query: 406
length of database: 18,247,518
effective HSP length: 105
effective length of query: 301
effective length of database: 14,271,588
effective search space: 4295747988
effective search space used: 4295747988
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.