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Search of human proteins with 8400715
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|8400715 microtubule-associated protein tau isoform 4 [Homo
sapiens]
(352 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|8400715 microtubule-associated protein tau isoform 4 [Homo sa... 710 0.0
gi|8400711 microtubule-associated protein tau isoform 3 [Homo sa... 694 0.0
gi|178557736 microtubule-associated protein tau isoform 5 [Homo ... 679 0.0
gi|6754638 microtubule-associated protein tau isoform 2 [Homo sa... 660 0.0
gi|82534351 microtubule-associated protein tau isoform 1 [Homo s... 530 e-151
gi|178557734 microtubule-associated protein tau isoform 6 [Homo ... 519 e-147
gi|87578396 microtubule-associated protein 2 isoform 1 [Homo sap... 274 8e-74
gi|87578392 microtubule-associated protein 2 isoform 2 [Homo sap... 274 8e-74
gi|87578394 microtubule-associated protein 2 isoform 5 [Homo sap... 261 9e-70
gi|87578255 microtubule-associated protein 2 isoform 4 [Homo sap... 261 9e-70
gi|197276600 microtubule-associated protein 4 isoform 4 [Homo sa... 165 5e-41
gi|197276602 microtubule-associated protein 4 isoform 5 [Homo sa... 151 7e-37
gi|47519675 microtubule-associated protein 4 isoform 2 [Homo sap... 128 9e-30
gi|47519639 microtubule-associated protein 4 isoform 1 [Homo sap... 128 9e-30
gi|122937267 lemur tyrosine kinase 3 [Homo sapiens] 50 3e-06
gi|163965366 nascent polypeptide-associated complex alpha subuni... 50 4e-06
gi|150170670 piccolo isoform 2 [Homo sapiens] 49 9e-06
gi|150378539 piccolo isoform 1 [Homo sapiens] 49 9e-06
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 49 9e-06
gi|54860079 nadrin isoform 1 [Homo sapiens] 48 1e-05
gi|19913396 smoothelin isoform b [Homo sapiens] 47 2e-05
gi|19913394 smoothelin isoform c [Homo sapiens] 47 2e-05
gi|47132519 Ras association and pleckstrin homology domains 1 is... 47 3e-05
gi|186928844 Cdc42 GTPase-activating protein [Homo sapiens] 47 3e-05
gi|19913398 smoothelin isoform a [Homo sapiens] 47 3e-05
gi|54860105 nadrin isoform 2 [Homo sapiens] 47 3e-05
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 46 4e-05
gi|149773456 hypothetical protein LOC643314 [Homo sapiens] 46 6e-05
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 45 7e-05
gi|7662234 rab11-family interacting protein 3 isoform 1 [Homo sa... 44 2e-04
>gi|8400715 microtubule-associated protein tau isoform 4 [Homo
sapiens]
Length = 352
Score = 710 bits (1833), Expect = 0.0
Identities = 352/352 (100%), Positives = 352/352 (100%)
Query: 1 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKAEEAGIGDTPSLEDEA 60
MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKAEEAGIGDTPSLEDEA
Sbjct: 1 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKAEEAGIGDTPSLEDEA 60
Query: 61 AGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPA 120
AGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPA
Sbjct: 61 AGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPA 120
Query: 121 PKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSS 180
PKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSS
Sbjct: 121 PKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSS 180
Query: 181 AKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIVYKPVDLSKVTSKCGSLGNIH 240
AKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIVYKPVDLSKVTSKCGSLGNIH
Sbjct: 181 AKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIVYKPVDLSKVTSKCGSLGNIH 240
Query: 241 HKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHG 300
HKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHG
Sbjct: 241 HKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHG 300
Query: 301 AEIVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL 352
AEIVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL
Sbjct: 301 AEIVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL 352
>gi|8400711 microtubule-associated protein tau isoform 3 [Homo
sapiens]
Length = 383
Score = 694 bits (1791), Expect = 0.0
Identities = 352/383 (91%), Positives = 352/383 (91%), Gaps = 31/383 (8%)
Query: 1 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKAEEAGIGDTPSLEDEA 60
MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKAEEAGIGDTPSLEDEA
Sbjct: 1 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKAEEAGIGDTPSLEDEA 60
Query: 61 AGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPA 120
AGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPA
Sbjct: 61 AGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPA 120
Query: 121 PKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSS 180
PKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSS
Sbjct: 121 PKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSS 180
Query: 181 AKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQI--------------------- 219
AKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQI
Sbjct: 181 AKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSKCGSKDNIK 240
Query: 220 ----------VYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLD 269
VYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLD
Sbjct: 241 HVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLD 300
Query: 270 NITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSNVSSTGSID 329
NITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSNVSSTGSID
Sbjct: 301 NITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSNVSSTGSID 360
Query: 330 MVDSPQLATLADEVSASLAKQGL 352
MVDSPQLATLADEVSASLAKQGL
Sbjct: 361 MVDSPQLATLADEVSASLAKQGL 383
>gi|178557736 microtubule-associated protein tau isoform 5 [Homo
sapiens]
Length = 412
Score = 679 bits (1751), Expect = 0.0
Identities = 352/412 (85%), Positives = 352/412 (85%), Gaps = 60/412 (14%)
Query: 1 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLK---------------- 44
MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLK
Sbjct: 1 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG 60
Query: 45 -------------AEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKT 91
AEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKT
Sbjct: 61 SETSDAKSTPTAEAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKT 120
Query: 92 KIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSR 151
KIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSR
Sbjct: 121 KIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSR 180
Query: 152 SRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQ 211
SRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQ
Sbjct: 181 SRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQ 240
Query: 212 PGGGKVQI-------------------------------VYKPVDLSKVTSKCGSLGNIH 240
PGGGKVQI VYKPVDLSKVTSKCGSLGNIH
Sbjct: 241 PGGGKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIH 300
Query: 241 HKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHG 300
HKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHG
Sbjct: 301 HKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHG 360
Query: 301 AEIVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL 352
AEIVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL
Sbjct: 361 AEIVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL 412
>gi|6754638 microtubule-associated protein tau isoform 2 [Homo
sapiens]
Length = 441
Score = 660 bits (1703), Expect = 0.0
Identities = 350/441 (79%), Positives = 351/441 (79%), Gaps = 89/441 (20%)
Query: 1 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLK-----------AEEAG 49
MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLK +EE G
Sbjct: 1 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG 60
Query: 50 -----------------------------------------------IGDTPSLEDEAAG 62
IGDTPSLEDEAAG
Sbjct: 61 SETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAG 120
Query: 63 HVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPK 122
HVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPK
Sbjct: 121 HVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPK 180
Query: 123 TPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAK 182
TPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAK
Sbjct: 181 TPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAK 240
Query: 183 SRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGK-------------------------- 216
SRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGK
Sbjct: 241 SRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSKCGSKDNIKHV 300
Query: 217 -----VQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNI 271
VQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNI
Sbjct: 301 PGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNI 360
Query: 272 THVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSNVSSTGSIDMV 331
THVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSNVSSTGSIDMV
Sbjct: 361 THVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSNVSSTGSIDMV 420
Query: 332 DSPQLATLADEVSASLAKQGL 352
DSPQLATLADEVSASLAKQGL
Sbjct: 421 DSPQLATLADEVSASLAKQGL 441
>gi|82534351 microtubule-associated protein tau isoform 1 [Homo
sapiens]
Length = 758
Score = 530 bits (1366), Expect = e-151
Identities = 273/331 (82%), Positives = 280/331 (84%), Gaps = 31/331 (9%)
Query: 53 TPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATR 112
+P++ E V+ +G+ + K KGADGKTKIATPRGAAPPGQKGQANATR
Sbjct: 428 SPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANATR 487
Query: 113 IPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVR 172
IPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVR
Sbjct: 488 IPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVR 547
Query: 173 TPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQI------------- 219
TPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQI
Sbjct: 548 TPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSK 607
Query: 220 ------------------VYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRV 261
VYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRV
Sbjct: 608 CGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRV 667
Query: 262 QSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSN 321
QSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSN
Sbjct: 668 QSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSN 727
Query: 322 VSSTGSIDMVDSPQLATLADEVSASLAKQGL 352
VSSTGSIDMVDSPQLATLADEVSASLAKQGL
Sbjct: 728 VSSTGSIDMVDSPQLATLADEVSASLAKQGL 758
Score = 119 bits (297), Expect = 5e-27
Identities = 99/315 (31%), Positives = 120/315 (38%), Gaps = 141/315 (44%)
Query: 1 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLK-----------AEEAG 49
MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLK +EE G
Sbjct: 1 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG 60
Query: 50 -----------------------------------------------IGDTPSLEDEAAG 62
IGDTPSLEDEAAG
Sbjct: 61 SETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAG 120
Query: 63 HVTQ--------------------------------------ARMVSKSKDGTGSDDKKA 84
HVTQ R ++ GTG +D +
Sbjct: 121 HVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAPLLPEGPREATRQPSGTGPEDTEG 180
Query: 85 -----------------------KGADGKTKIATPRGAAPPGQKGQANATR-----IPAK 116
KGA GK + PG K + + R P
Sbjct: 181 GRHAPELLKHQLLGDLHQEGPPLKGAGGKER---------PGSKEEVDEDRDVDESSPQD 231
Query: 117 TPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPK-KVAVVRTPP 175
+PP+ +P G PP++ R S PG P ++P P K + + P
Sbjct: 232 SPPSKASPAQDGRPPQTAAREATSIPGFPA-------EGAIPLPVDFLSKVSTEIPASEP 284
Query: 176 KSPSSAKSRLQTAPV 190
PS +++ Q AP+
Sbjct: 285 DGPSVGRAKGQDAPL 299
>gi|178557734 microtubule-associated protein tau isoform 6 [Homo
sapiens]
Length = 776
Score = 519 bits (1337), Expect = e-147
Identities = 273/349 (78%), Positives = 280/349 (80%), Gaps = 49/349 (14%)
Query: 53 TPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATR 112
+P++ E V+ +G+ + K KGADGKTKIATPRGAAPPGQKGQANATR
Sbjct: 428 SPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANATR 487
Query: 113 IPAKTPPAPKTPPSS------------------GEPPKSGDRSGYSSPGSPGTPGSRSRT 154
IPAKTPPAPKTPPSS GEPPKSGDRSGYSSPGSPGTPGSRSRT
Sbjct: 488 IPAKTPPAPKTPPSSATKQVQRRPPPAGPRSERGEPPKSGDRSGYSSPGSPGTPGSRSRT 547
Query: 155 PSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGG 214
PSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGG
Sbjct: 548 PSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGG 607
Query: 215 GKVQI-------------------------------VYKPVDLSKVTSKCGSLGNIHHKP 243
GKVQI VYKPVDLSKVTSKCGSLGNIHHKP
Sbjct: 608 GKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKP 667
Query: 244 GGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEI 303
GGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEI
Sbjct: 668 GGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEI 727
Query: 304 VYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL 352
VYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL
Sbjct: 728 VYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL 776
Score = 119 bits (297), Expect = 5e-27
Identities = 99/315 (31%), Positives = 120/315 (38%), Gaps = 141/315 (44%)
Query: 1 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLK-----------AEEAG 49
MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLK +EE G
Sbjct: 1 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG 60
Query: 50 -----------------------------------------------IGDTPSLEDEAAG 62
IGDTPSLEDEAAG
Sbjct: 61 SETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAG 120
Query: 63 HVTQ--------------------------------------ARMVSKSKDGTGSDDKKA 84
HVTQ R ++ GTG +D +
Sbjct: 121 HVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAPLLPEGPREATRQPSGTGPEDTEG 180
Query: 85 -----------------------KGADGKTKIATPRGAAPPGQKGQANATR-----IPAK 116
KGA GK + PG K + + R P
Sbjct: 181 GRHAPELLKHQLLGDLHQEGPPLKGAGGKER---------PGSKEEVDEDRDVDESSPQD 231
Query: 117 TPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPK-KVAVVRTPP 175
+PP+ +P G PP++ R S PG P ++P P K + + P
Sbjct: 232 SPPSKASPAQDGRPPQTAAREATSIPGFPA-------EGAIPLPVDFLSKVSTEIPASEP 284
Query: 176 KSPSSAKSRLQTAPV 190
PS +++ Q AP+
Sbjct: 285 DGPSVGRAKGQDAPL 299
>gi|87578396 microtubule-associated protein 2 isoform 1 [Homo sapiens]
Length = 1827
Score = 274 bits (701), Expect = 8e-74
Identities = 149/257 (57%), Positives = 188/257 (73%), Gaps = 22/257 (8%)
Query: 103 GQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSS--PGSPGTPGSRSRTPSLPTP 160
G+ G + T P T P TPPS YSS PG+PGTP S RTP P
Sbjct: 1586 GKSGTSTPTT-PGSTAITPGTPPS------------YSSRTPGTPGTP-SYPRTPHTPGT 1631
Query: 161 PTR-----EPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGG 215
P KKVA++RTPPKSP++ K +L+ P+PDLKNVKSKIGST+N+K+QP GG
Sbjct: 1632 PKSAILVPSEKKVAIIRTPPKSPATPK-QLRLINQPLPDLKNVKSKIGSTDNIKYQPKGG 1690
Query: 216 KVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVP 275
+VQIV K +DLS VTSKCGSL NI H+PGGG+V+++S KLDFK++ Q+K+GSLDN HVP
Sbjct: 1691 QVQIVTKKIDLSHVTSKCGSLKNIRHRPGGGRVKIESVKLDFKEKAQAKVGSLDNAHHVP 1750
Query: 276 GGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQ 335
GGGN KI++ KL FRE+AKA+ DHGAEI+ +SP S SPR LSNVSS+GSI++++SPQ
Sbjct: 1751 GGGNVKIDSQKLNFREHAKARVDHGAEIITQSPGRSSVASPRRLSNVSSSGSINLLESPQ 1810
Query: 336 LATLADEVSASLAKQGL 352
LATLA++V+A+LAKQGL
Sbjct: 1811 LATLAEDVTAALAKQGL 1827
>gi|87578392 microtubule-associated protein 2 isoform 2 [Homo
sapiens]
Length = 471
Score = 274 bits (701), Expect = 8e-74
Identities = 149/257 (57%), Positives = 188/257 (73%), Gaps = 22/257 (8%)
Query: 103 GQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSS--PGSPGTPGSRSRTPSLPTP 160
G+ G + T P T P TPPS YSS PG+PGTP S RTP P
Sbjct: 230 GKSGTSTPTT-PGSTAITPGTPPS------------YSSRTPGTPGTP-SYPRTPHTPGT 275
Query: 161 PTR-----EPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGG 215
P KKVA++RTPPKSP++ K +L+ P+PDLKNVKSKIGST+N+K+QP GG
Sbjct: 276 PKSAILVPSEKKVAIIRTPPKSPATPK-QLRLINQPLPDLKNVKSKIGSTDNIKYQPKGG 334
Query: 216 KVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVP 275
+VQIV K +DLS VTSKCGSL NI H+PGGG+V+++S KLDFK++ Q+K+GSLDN HVP
Sbjct: 335 QVQIVTKKIDLSHVTSKCGSLKNIRHRPGGGRVKIESVKLDFKEKAQAKVGSLDNAHHVP 394
Query: 276 GGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQ 335
GGGN KI++ KL FRE+AKA+ DHGAEI+ +SP S SPR LSNVSS+GSI++++SPQ
Sbjct: 395 GGGNVKIDSQKLNFREHAKARVDHGAEIITQSPGRSSVASPRRLSNVSSSGSINLLESPQ 454
Query: 336 LATLADEVSASLAKQGL 352
LATLA++V+A+LAKQGL
Sbjct: 455 LATLAEDVTAALAKQGL 471
>gi|87578394 microtubule-associated protein 2 isoform 5 [Homo
sapiens]
Length = 559
Score = 261 bits (666), Expect = 9e-70
Identities = 150/288 (52%), Positives = 188/288 (65%), Gaps = 53/288 (18%)
Query: 103 GQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSS--PGSPGTPGSRSRTPSLPTP 160
G+ G + T P T P TPPS YSS PG+PGTP S RTP P
Sbjct: 287 GKSGTSTPTT-PGSTAITPGTPPS------------YSSRTPGTPGTP-SYPRTPHTPGT 332
Query: 161 PTR-----EPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQP--- 212
P KKVA++RTPPKSP++ K +L+ P+PDLKNVKSKIGST+N+K+QP
Sbjct: 333 PKSAILVPSEKKVAIIRTPPKSPATPK-QLRLINQPLPDLKNVKSKIGSTDNIKYQPKGG 391
Query: 213 ----------------------------GGGKVQIVYKPVDLSKVTSKCGSLGNIHHKPG 244
GGG VQIV K +DLS VTSKCGSL NI H+PG
Sbjct: 392 QVRILNKKIDFSKVQSRCGSKDNIKHSAGGGNVQIVTKKIDLSHVTSKCGSLKNIRHRPG 451
Query: 245 GGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIV 304
GG+V+++S KLDFK++ Q+K+GSLDN HVPGGGN KI++ KL FRE+AKA+ DHGAEI+
Sbjct: 452 GGRVKIESVKLDFKEKAQAKVGSLDNAHHVPGGGNVKIDSQKLNFREHAKARVDHGAEII 511
Query: 305 YKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL 352
+SP S SPR LSNVSS+GSI++++SPQLATLA++V+A+LAKQGL
Sbjct: 512 TQSPGRSSVASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL 559
>gi|87578255 microtubule-associated protein 2 isoform 4 [Homo
sapiens]
Length = 502
Score = 261 bits (666), Expect = 9e-70
Identities = 150/288 (52%), Positives = 188/288 (65%), Gaps = 53/288 (18%)
Query: 103 GQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSS--PGSPGTPGSRSRTPSLPTP 160
G+ G + T P T P TPPS YSS PG+PGTP S RTP P
Sbjct: 230 GKSGTSTPTT-PGSTAITPGTPPS------------YSSRTPGTPGTP-SYPRTPHTPGT 275
Query: 161 PTR-----EPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQP--- 212
P KKVA++RTPPKSP++ K +L+ P+PDLKNVKSKIGST+N+K+QP
Sbjct: 276 PKSAILVPSEKKVAIIRTPPKSPATPK-QLRLINQPLPDLKNVKSKIGSTDNIKYQPKGG 334
Query: 213 ----------------------------GGGKVQIVYKPVDLSKVTSKCGSLGNIHHKPG 244
GGG VQIV K +DLS VTSKCGSL NI H+PG
Sbjct: 335 QVRILNKKIDFSKVQSRCGSKDNIKHSAGGGNVQIVTKKIDLSHVTSKCGSLKNIRHRPG 394
Query: 245 GGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIV 304
GG+V+++S KLDFK++ Q+K+GSLDN HVPGGGN KI++ KL FRE+AKA+ DHGAEI+
Sbjct: 395 GGRVKIESVKLDFKEKAQAKVGSLDNAHHVPGGGNVKIDSQKLNFREHAKARVDHGAEII 454
Query: 305 YKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL 352
+SP S SPR LSNVSS+GSI++++SPQLATLA++V+A+LAKQGL
Sbjct: 455 TQSPGRSSVASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL 502
>gi|197276600 microtubule-associated protein 4 isoform 4 [Homo
sapiens]
Length = 1135
Score = 165 bits (418), Expect = 5e-41
Identities = 103/265 (38%), Positives = 142/265 (53%), Gaps = 26/265 (9%)
Query: 70 VSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTP----P 125
+S+ K + S KK G A G P K +R P+ TP K P P
Sbjct: 858 LSRPKSTSTSSMKKTTTLSGTAPAA---GVVPSRVKATPMPSR-PSTTPFIDKKPTSAKP 913
Query: 126 SSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPP----------------TREPKKVA 169
SS P S + S+P T ++ P TR+P+ A
Sbjct: 914 SSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNA 973
Query: 170 VVRTPPKSPSSAKSRLQTAPVPMPDLK--NVKSKIGSTENLKHQPGGGKVQIVYKPVDLS 227
V +T S+ K + + +++SK GS +N+KH PGGG VQI K VD+S
Sbjct: 974 VTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDIS 1033
Query: 228 KVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKL 287
KV+SKCGS NI HKPGGG V+++S+KL+FK++ Q+K+GSLDN+ H+P GG KIET++L
Sbjct: 1034 KVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKIETYRL 1093
Query: 288 TFRENAKAKTDHGAEIVYKSPVVSG 312
TFR NA+A+TDHGA+IV + P G
Sbjct: 1094 TFRANARARTDHGADIVSRPPHFPG 1118
Score = 45.4 bits (106), Expect = 7e-05
Identities = 74/318 (23%), Positives = 110/318 (34%), Gaps = 86/318 (27%)
Query: 76 GTGSD------DKKAKGADGKTK-IATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSG 128
GTG+D + + KTK +AT + A K + T +P + PAP T
Sbjct: 680 GTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQ--PAPTTIGGLN 737
Query: 129 EPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTP-------------- 174
+ P S SG P P S PS+ +PK +A + P
Sbjct: 738 KKPMSL-ASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPA 796
Query: 175 ----------------------------------PKSPSSAKSRLQTAPVPMPDLKNV-- 198
PK P++ K+ + A V K+V
Sbjct: 797 SRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPA 856
Query: 199 ---KSKIGSTENLKH-------QPGGGKVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQV 248
+ K ST ++K P G +V V + + S+ + I KP +
Sbjct: 857 DLSRPKSTSTSSMKKTTTLSGTAPAAG---VVPSRVKATPMPSRPSTTPFIDKKPTSAKP 913
Query: 249 EVKSEKL----------DFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTD 298
+ +L D K+ V+SK+GS +NI H PGGG K+E K T K +
Sbjct: 914 SSTTPRLSRLATNTSAPDLKN-VRSKVGSTENIKHQPGGGRAKVE--KKTEAAATTRKPE 970
Query: 299 HGAEIVYKSPVVSGDTSP 316
A P+ S P
Sbjct: 971 SNAVTKTAGPIASAQKQP 988
Score = 33.5 bits (75), Expect = 0.29
Identities = 35/151 (23%), Positives = 57/151 (37%), Gaps = 11/151 (7%)
Query: 52 DTPSLEDEAAGHVTQARM-VSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANA 110
D P L + A V M +++++ G D D A +P G
Sbjct: 575 DVPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFMISPETVTGTGKK 634
Query: 111 TRIPAKTPPA-----PKTPPSSGEPPKSGDRSGYSSP--GSP---GTPGSRSRTPSLPTP 160
+PA+ + P +S S + SG + P G P GT + P+ P
Sbjct: 635 CSLPAEEDSVLEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTGNDITTPPNKELP 694
Query: 161 PTREPKKVAVVRTPPKSPSSAKSRLQTAPVP 191
P+ E K + T P S++K++ Q +P
Sbjct: 695 PSPEKKTKPLATTQPAKTSTSKAKTQPTSLP 725
>gi|197276602 microtubule-associated protein 4 isoform 5 [Homo
sapiens]
Length = 817
Score = 151 bits (382), Expect = 7e-37
Identities = 95/222 (42%), Positives = 120/222 (54%), Gaps = 24/222 (10%)
Query: 84 AKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRS---GYS 140
+K K T A G ++ +T +P K P A KT E K +S S
Sbjct: 536 SKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKK-PTAIKTEGKPAEVKKMTAKSVPADLS 594
Query: 141 SPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTP-----------PKSPSSAK------- 182
P S T + T T P V TP K P+SAK
Sbjct: 595 RPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPR 654
Query: 183 -SRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIVYKPVDLSKVTSKCGSLGNIHH 241
SRL T PDLKNV+SK+GSTEN+KHQPGGG+VQI K VD+SKV+SKCGS NI H
Sbjct: 655 LSRLATN-TSAPDLKNVRSKVGSTENIKHQPGGGRVQIQNKKVDISKVSSKCGSKANIKH 713
Query: 242 KPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIE 283
KPGGG V+++S+KL+FK++ Q+K+GSLDN+ H+P GG K E
Sbjct: 714 KPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTE 755
Score = 46.6 bits (109), Expect = 3e-05
Identities = 72/306 (23%), Positives = 111/306 (36%), Gaps = 89/306 (29%)
Query: 76 GTGSD------DKKAKGADGKTK-IATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSG 128
GTG+D + + KTK +AT + A K + T +P + PAP T
Sbjct: 415 GTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQ--PAPTTIGGLN 472
Query: 129 EPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTP-------------- 174
+ P S SG P P S PS+ +PK +A + P
Sbjct: 473 KKPMSL-ASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPA 531
Query: 175 ----------------------------------PKSPSSAKSRLQTAPVPMPDLKNV-- 198
PK P++ K+ + A V K+V
Sbjct: 532 SRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPA 591
Query: 199 ---KSKIGSTENLKH-------QPGGGKVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQV 248
+ K ST ++K P G +V V + + S+ + I KP +
Sbjct: 592 DLSRPKSTSTSSMKKTTTLSGTAPAAG---VVPSRVKATPMPSRPSTTPFIDKKPTSAKP 648
Query: 249 EVKSEKL----------DFKDRVQSKIGSLDNITHVPGGG-----NKKIETHKLTFRENA 293
+ +L D K+ V+SK+GS +NI H PGGG NKK++ K++ + +
Sbjct: 649 SSTTPRLSRLATNTSAPDLKN-VRSKVGSTENIKHQPGGGRVQIQNKKVDISKVSSKCGS 707
Query: 294 KAKTDH 299
KA H
Sbjct: 708 KANIKH 713
Score = 43.5 bits (101), Expect = 3e-04
Identities = 36/132 (27%), Positives = 56/132 (42%), Gaps = 16/132 (12%)
Query: 65 TQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTP 124
T +M KS+ T + KK + K+++A P KG T+ TP PK+
Sbjct: 340 TPQKMTEKSESKTPGEGKK----EDKSRMAEP-------MKGYMRPTKSRGLTPLLPKST 388
Query: 125 PSSGEPPKSGDRSGYSSP--GSP---GTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPS 179
E K +G + P G P GT + P+ PP+ E K + T P S
Sbjct: 389 IQEQERHKQLKSAGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTS 448
Query: 180 SAKSRLQTAPVP 191
++K++ Q +P
Sbjct: 449 TSKAKTQPTSLP 460
>gi|47519675 microtubule-associated protein 4 isoform 2 [Homo
sapiens]
Length = 887
Score = 128 bits (321), Expect = 9e-30
Identities = 85/236 (36%), Positives = 118/236 (50%), Gaps = 26/236 (11%)
Query: 70 VSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTP----P 125
+S+ K + S KK G A G P K +R P+ TP K P P
Sbjct: 593 LSRPKSTSTSSMKKTTTLSGTAPAA---GVVPSRVKATPMPSR-PSTTPFIDKKPTSAKP 648
Query: 126 SSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPP----------------TREPKKVA 169
SS P S + S+P T ++ P TR+P+ A
Sbjct: 649 SSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNA 708
Query: 170 VVRTPPKSPSSAKSRLQTAPVPMPDLK--NVKSKIGSTENLKHQPGGGKVQIVYKPVDLS 227
V +T S+ K + + +++SK GS +N+KH PGGG VQI K VD+S
Sbjct: 709 VTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDIS 768
Query: 228 KVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIE 283
KV+SKCGS NI HKPGGG V+++S+KL+FK++ Q+K+GSLDN+ H+P GG K E
Sbjct: 769 KVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTE 824
Score = 94.4 bits (233), Expect = 1e-19
Identities = 85/293 (29%), Positives = 113/293 (38%), Gaps = 112/293 (38%)
Query: 115 AKTPPAPKTP--PSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVR 172
AK P +P P+S +SG +S + + S PS +P T PKK ++
Sbjct: 514 AKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIK 573
Query: 173 TP--------------------PKSPSSAK------------------SRLQTAPV---- 190
T PKS S++ SR++ P+
Sbjct: 574 TEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRP 633
Query: 191 ---PMPDLKNVKSKIGST--------------------------ENLKHQPGGG------ 215
P D K +K ST EN+KHQPGGG
Sbjct: 634 STTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEK 693
Query: 216 --------------------------------KVQIVYKPVDLSKVTSKCGSLGNIHHKP 243
KVQIV K V S + SKCGS NI H P
Sbjct: 694 KTEAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVP 753
Query: 244 GGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAK 296
GGG V+++++K+D +V SK GS NI H PGGG+ KIE+ KL F+E A+AK
Sbjct: 754 GGGNVQIQNKKVDI-SKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAK 805
Score = 45.4 bits (106), Expect = 7e-05
Identities = 74/318 (23%), Positives = 110/318 (34%), Gaps = 86/318 (27%)
Query: 76 GTGSD------DKKAKGADGKTK-IATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSG 128
GTG+D + + KTK +AT + A K + T +P + PAP T
Sbjct: 415 GTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQ--PAPTTIGGLN 472
Query: 129 EPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTP-------------- 174
+ P S SG P P S PS+ +PK +A + P
Sbjct: 473 KKPMSL-ASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPA 531
Query: 175 ----------------------------------PKSPSSAKSRLQTAPVPMPDLKNV-- 198
PK P++ K+ + A V K+V
Sbjct: 532 SRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPA 591
Query: 199 ---KSKIGSTENLKH-------QPGGGKVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQV 248
+ K ST ++K P G +V V + + S+ + I KP +
Sbjct: 592 DLSRPKSTSTSSMKKTTTLSGTAPAAG---VVPSRVKATPMPSRPSTTPFIDKKPTSAKP 648
Query: 249 EVKSEKL----------DFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTD 298
+ +L D K+ V+SK+GS +NI H PGGG K+E K T K +
Sbjct: 649 SSTTPRLSRLATNTSAPDLKN-VRSKVGSTENIKHQPGGGRAKVE--KKTEAAATTRKPE 705
Query: 299 HGAEIVYKSPVVSGDTSP 316
A P+ S P
Sbjct: 706 SNAVTKTAGPIASAQKQP 723
Score = 43.5 bits (101), Expect = 3e-04
Identities = 36/132 (27%), Positives = 56/132 (42%), Gaps = 16/132 (12%)
Query: 65 TQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTP 124
T +M KS+ T + KK + K+++A P KG T+ TP PK+
Sbjct: 340 TPQKMTEKSESKTPGEGKK----EDKSRMAEP-------MKGYMRPTKSRGLTPLLPKST 388
Query: 125 PSSGEPPKSGDRSGYSSP--GSP---GTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPS 179
E K +G + P G P GT + P+ PP+ E K + T P S
Sbjct: 389 IQEQERHKQLKSAGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTS 448
Query: 180 SAKSRLQTAPVP 191
++K++ Q +P
Sbjct: 449 TSKAKTQPTSLP 460
>gi|47519639 microtubule-associated protein 4 isoform 1 [Homo sapiens]
Length = 1152
Score = 128 bits (321), Expect = 9e-30
Identities = 85/236 (36%), Positives = 118/236 (50%), Gaps = 26/236 (11%)
Query: 70 VSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTP----P 125
+S+ K + S KK G A G P K +R P+ TP K P P
Sbjct: 858 LSRPKSTSTSSMKKTTTLSGTAPAA---GVVPSRVKATPMPSR-PSTTPFIDKKPTSAKP 913
Query: 126 SSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPP----------------TREPKKVA 169
SS P S + S+P T ++ P TR+P+ A
Sbjct: 914 SSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNA 973
Query: 170 VVRTPPKSPSSAKSRLQTAPVPMPDLK--NVKSKIGSTENLKHQPGGGKVQIVYKPVDLS 227
V +T S+ K + + +++SK GS +N+KH PGGG VQI K VD+S
Sbjct: 974 VTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDIS 1033
Query: 228 KVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIE 283
KV+SKCGS NI HKPGGG V+++S+KL+FK++ Q+K+GSLDN+ H+P GG K E
Sbjct: 1034 KVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTE 1089
Score = 94.4 bits (233), Expect = 1e-19
Identities = 85/293 (29%), Positives = 113/293 (38%), Gaps = 112/293 (38%)
Query: 115 AKTPPAPKTP--PSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVR 172
AK P +P P+S +SG +S + + S PS +P T PKK ++
Sbjct: 779 AKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIK 838
Query: 173 TP--------------------PKSPSSAK------------------SRLQTAPV---- 190
T PKS S++ SR++ P+
Sbjct: 839 TEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRP 898
Query: 191 ---PMPDLKNVKSKIGST--------------------------ENLKHQPGGG------ 215
P D K +K ST EN+KHQPGGG
Sbjct: 899 STTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEK 958
Query: 216 --------------------------------KVQIVYKPVDLSKVTSKCGSLGNIHHKP 243
KVQIV K V S + SKCGS NI H P
Sbjct: 959 KTEAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVP 1018
Query: 244 GGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAK 296
GGG V+++++K+D +V SK GS NI H PGGG+ KIE+ KL F+E A+AK
Sbjct: 1019 GGGNVQIQNKKVDI-SKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAK 1070
Score = 45.4 bits (106), Expect = 7e-05
Identities = 74/318 (23%), Positives = 110/318 (34%), Gaps = 86/318 (27%)
Query: 76 GTGSD------DKKAKGADGKTK-IATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSG 128
GTG+D + + KTK +AT + A K + T +P + PAP T
Sbjct: 680 GTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQ--PAPTTIGGLN 737
Query: 129 EPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTP-------------- 174
+ P S SG P P S PS+ +PK +A + P
Sbjct: 738 KKPMSL-ASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPA 796
Query: 175 ----------------------------------PKSPSSAKSRLQTAPVPMPDLKNV-- 198
PK P++ K+ + A V K+V
Sbjct: 797 SRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPA 856
Query: 199 ---KSKIGSTENLKH-------QPGGGKVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQV 248
+ K ST ++K P G +V V + + S+ + I KP +
Sbjct: 857 DLSRPKSTSTSSMKKTTTLSGTAPAAG---VVPSRVKATPMPSRPSTTPFIDKKPTSAKP 913
Query: 249 EVKSEKL----------DFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTD 298
+ +L D K+ V+SK+GS +NI H PGGG K+E K T K +
Sbjct: 914 SSTTPRLSRLATNTSAPDLKN-VRSKVGSTENIKHQPGGGRAKVE--KKTEAAATTRKPE 970
Query: 299 HGAEIVYKSPVVSGDTSP 316
A P+ S P
Sbjct: 971 SNAVTKTAGPIASAQKQP 988
Score = 33.5 bits (75), Expect = 0.29
Identities = 35/151 (23%), Positives = 57/151 (37%), Gaps = 11/151 (7%)
Query: 52 DTPSLEDEAAGHVTQARM-VSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANA 110
D P L + A V M +++++ G D D A +P G
Sbjct: 575 DVPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFMISPETVTGTGKK 634
Query: 111 TRIPAKTPPA-----PKTPPSSGEPPKSGDRSGYSSP--GSP---GTPGSRSRTPSLPTP 160
+PA+ + P +S S + SG + P G P GT + P+ P
Sbjct: 635 CSLPAEEDSVLEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTGNDITTPPNKELP 694
Query: 161 PTREPKKVAVVRTPPKSPSSAKSRLQTAPVP 191
P+ E K + T P S++K++ Q +P
Sbjct: 695 PSPEKKTKPLATTQPAKTSTSKAKTQPTSLP 725
>gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]
Length = 1489
Score = 50.1 bits (118), Expect = 3e-06
Identities = 47/157 (29%), Positives = 64/157 (40%), Gaps = 14/157 (8%)
Query: 48 AGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATP-RGAAPPGQKG 106
AG G P+L H + +++ G+ +D A A + P GAA P G
Sbjct: 719 AGWGGHPAL---GCPHPPEDDSSLRAERGSLADLPMAPPASAPPEFLDPLMGAAAPQYPG 775
Query: 107 QANATRIPAKTPP--APKTPPSSGEPPK--SGDRSGYSSPG-SPGTPGSRSRTP-----S 156
+ P PP AP P +S +PP + SG SSPG PG G + TP +
Sbjct: 776 RGPPPAPPPPPPPPRAPADPAASPDPPSAVASPGSGLSSPGPKPGDSGYETETPFSPEGA 835
Query: 157 LPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMP 193
P E + V R PP+ P R P P+P
Sbjct: 836 FPGGGAAEEEGVPRPRAPPEPPDPGAPRPPPDPGPLP 872
Score = 35.8 bits (81), Expect = 0.059
Identities = 43/192 (22%), Positives = 65/192 (33%), Gaps = 34/192 (17%)
Query: 86 GADGKTKIATPRGAAPPGQKGQANATRI-----------PAKTPPAPKTPPSSGEPPKSG 134
G+ G+ + T G AP G G + P PP P+ P EP
Sbjct: 1139 GSGGRAPVGT--GTAPGGGPGSGVDAKAGWVDNTRPQPPPPPLPPPPEAQPRRLEPAPPR 1196
Query: 135 DRSGYSSPGSPGTPGSRSRTPSL------PTPPTRE----PKKVAVVRTPPKSPSSAKSR 184
R + G PG P SR+ + P P R+ P+ + P + K+R
Sbjct: 1197 ARPEVAPEGEPGAPDSRAGGDTALSGDGDPPKPERKGPEMPRLFLDLGPPQGNSEQIKAR 1256
Query: 185 LQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIVYKPVDLSKVTSKCGSLGNIHHKPG 244
L + +P L L PG G + ++ D + G G
Sbjct: 1257 LSRLSLALPPL-----------TLTPFPGPGPRRPPWEGADAGAAGGEAGGAGAPGPAEE 1305
Query: 245 GGQVEVKSEKLD 256
G+ E + E+ D
Sbjct: 1306 DGEDEDEDEEED 1317
Score = 31.2 bits (69), Expect = 1.5
Identities = 28/113 (24%), Positives = 44/113 (38%), Gaps = 23/113 (20%)
Query: 96 PRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSP-GTPGS---- 150
P G AP + R +T AP+ P + SG R+ + +P G PGS
Sbjct: 1103 PLGPAPKNGTLEPGTERRAPETGGAPRAPGAGRLDLGSGGRAPVGTGTAPGGGPGSGVDA 1162
Query: 151 ----------RSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMP 193
+ P LP PP +P+++ P+ ++R + AP P
Sbjct: 1163 KAGWVDNTRPQPPPPPLPPPPEAQPRRL--------EPAPPRARPEVAPEGEP 1207
Score = 29.3 bits (64), Expect = 5.6
Identities = 44/187 (23%), Positives = 63/187 (33%), Gaps = 37/187 (19%)
Query: 15 AGTYGLGDRKDQGGYTMHQDQEGDTDAGLKAEEAG--------IGDTPSLEDEAAGHVTQ 66
AG G ++ G +D+E D +A AG P + A +
Sbjct: 1294 AGGAGAPGPAEEDGEDEDEDEEEDEEAAAPGAAAGPRGPGRARAAPVPVVVSSADADAAR 1353
Query: 67 ARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPP---GQKGQANATRIPA-------- 115
+ K G+D+ + + K K+ + G Q+ N + A
Sbjct: 1354 P-LRGLLKSPRGADEPEDSELERKRKMVSFHGDVTVYLFDQETPTNELSVQAPPEGDTDP 1412
Query: 116 KTPPAPKTPPSSGEP----PKSGDRSGYS-----------SPGSPGTPGSRSRTPSL--P 158
TPPAP TPP P P + G S PG P S +P+L P
Sbjct: 1413 STPPAPPTPPHPATPGDGFPSNDSGFGGSFEWAEDFPLLPPPGPPLCFSRFSVSPALETP 1472
Query: 159 TPPTREP 165
PP R P
Sbjct: 1473 GPPARAP 1479
Score = 28.9 bits (63), Expect = 7.3
Identities = 26/81 (32%), Positives = 30/81 (37%), Gaps = 13/81 (16%)
Query: 76 GTGSDDKKAKGADGKTKIATP---RGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPK 132
G+G K D + TP GA P G G A +P P AP PP G P
Sbjct: 809 GSGLSSPGPKPGDSGYETETPFSPEGAFPGG--GAAEEEGVPR--PRAPPEPPDPGAPRP 864
Query: 133 SGDRSGYSSPGSPGTPGSRSR 153
D PG PG R +
Sbjct: 865 PPD------PGPLPLPGPREK 879
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 49.7 bits (117), Expect = 4e-06
Identities = 38/123 (30%), Positives = 50/123 (40%), Gaps = 22/123 (17%)
Query: 95 TPRGAAPPGQKGQAN------ATRIPAKTPPAPK--------TPPSSGEPPKSGDRSGYS 140
TP A PP KG A PA TPP+PK TP S G P + G +
Sbjct: 1311 TPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPT 1370
Query: 141 SP-------GSPG-TPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPM 192
P G P TP S R P++P+P + +P K+P++ +R A
Sbjct: 1371 PPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSK 1430
Query: 193 PDL 195
DL
Sbjct: 1431 GDL 1433
Score = 48.9 bits (115), Expect = 7e-06
Identities = 34/107 (31%), Positives = 41/107 (38%), Gaps = 15/107 (14%)
Query: 96 PRGAAPPGQKG------QANATRIPAKTPPAPK----TPPSSGEPPKSG-----DRSGYS 140
P A PP KG A PA TPP+PK TPP G P + G +
Sbjct: 1105 PPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLA 1164
Query: 141 SPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQT 187
+P G P + + TP P P TP +P S K L T
Sbjct: 1165 TPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLAT 1211
Score = 47.8 bits (112), Expect = 2e-05
Identities = 36/112 (32%), Positives = 45/112 (40%), Gaps = 17/112 (15%)
Query: 95 TPRGAAPPGQKGQANATRIP-------AKTPPAPKTPPSSGEPPKSGDRSGY----SSPG 143
TP PP KG AT P A TPP+PK P++ PK + S G
Sbjct: 1010 TPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKG 1069
Query: 144 SPGTPGSR-SRTPSLPTPPTRE-----PKKVAVVRTPPKSPSSAKSRLQTAP 189
P TP + + TP TPP+ + P P +P S K L T P
Sbjct: 1070 GPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPP 1121
Score = 47.4 bits (111), Expect = 2e-05
Identities = 46/155 (29%), Positives = 59/155 (38%), Gaps = 25/155 (16%)
Query: 62 GHVTQARMVSKSKDGTGSDDKKAKGADGKTKIA---------TPRGAAPPGQKGQAN--- 109
G T A + + T S KKA+ I TP A PP KG
Sbjct: 899 GPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPS 958
Query: 110 ---ATRIPAKTPPAPKTPPSSGEP---PKSGDRSGYSSPGSPGTPGSR-SRTPSLPTPPT 162
A PA TPP+PK P++ P P + S G P TP + + TP TPP+
Sbjct: 959 PKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPS 1018
Query: 163 REPKKVAV-----VRTPP-KSPSSAKSRLQTAPVP 191
+ A TPP +P S K P+P
Sbjct: 1019 PKGSPAATPFPKGASTPPAATPPSPKGSPAATPLP 1053
Score = 46.6 bits (109), Expect = 3e-05
Identities = 37/109 (33%), Positives = 43/109 (39%), Gaps = 5/109 (4%)
Query: 85 KGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGS 144
KGA + P P A PA TPP+PK P + PPK +P S
Sbjct: 1284 KGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGT-PPPKGAPTPPAVTPPS 1342
Query: 145 P-GTPGSRSRTPSLPTPPTREPKKVAVVRTPP-KSPSSAKSRLQTAPVP 191
P GTP + TPS PT K TPP +PS T P P
Sbjct: 1343 PKGTPTLPATTPSSKGGPTTPSSKEG--PTPPAATPSHKGGPAMTPPSP 1389
Score = 46.2 bits (108), Expect = 4e-05
Identities = 36/146 (24%), Positives = 50/146 (34%), Gaps = 9/146 (6%)
Query: 53 TPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATR 112
+P+ G T S G+ + KGA P P A
Sbjct: 1022 SPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPT 1081
Query: 113 IPAKTPPAPKTPPSSGEPPKS---------GDRSGYSSPGSPGTPGSRSRTPSLPTPPTR 163
PA TPP+PK P++ P + + G ++P G P + + TP P
Sbjct: 1082 PPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLA 1141
Query: 164 EPKKVAVVRTPPKSPSSAKSRLQTAP 189
P TP +P S K L T P
Sbjct: 1142 TPPPKGAPTTPAATPPSPKGGLATPP 1167
Score = 45.4 bits (106), Expect = 7e-05
Identities = 44/143 (30%), Positives = 52/143 (36%), Gaps = 20/143 (13%)
Query: 85 KGADGKTKIATPR----GAAPPGQKGQANATRIPAKTPPAPK----TPPSSGEPPKSG-- 134
KGA T ATP G A P KG A PA TPP+PK TP G P
Sbjct: 1146 KGAP-TTPAATPPSPKGGLATPPPKG---APTTPAATPPSPKGGLATPSPKGAPTTPAAT 1201
Query: 135 ---DRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAP-- 189
+ G ++P G P + + TP P P TP +P S K T P
Sbjct: 1202 PPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPK 1261
Query: 190 -VPMPDLKNVKSKIGSTENLKHQ 211
P P S G H+
Sbjct: 1262 GAPTPPAATPPSLKGGLATPPHK 1284
Score = 45.4 bits (106), Expect = 7e-05
Identities = 39/133 (29%), Positives = 53/133 (39%), Gaps = 25/133 (18%)
Query: 85 KGADGKTKIATPRGAAPPGQKGQANATRI----PAKTPPAPKT-----PPSSGE------ 129
KG T + RG A P KG + + P K P P T PS G+
Sbjct: 1379 KGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAV 1438
Query: 130 --------PPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSS- 180
P S + G ++P S G P + TP P P PK+VA +P K+P++
Sbjct: 1439 TPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPP-APKQVATSSSPKKAPATP 1497
Query: 181 AKSRLQTAPVPMP 193
A T P +P
Sbjct: 1498 APMGAPTLPAVIP 1510
Score = 43.5 bits (101), Expect = 3e-04
Identities = 33/124 (26%), Positives = 51/124 (41%), Gaps = 14/124 (11%)
Query: 95 TPRGAAPPGQKG------QANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTP 148
TP A PP KG A PA TPP+PK P++ P + + P G+P
Sbjct: 964 TPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSP 1023
Query: 149 GSR-----SRTPSLPTPPTRE--PKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSK 201
+ + TP TPP+ + P + + P +P++ + P P LK +
Sbjct: 1024 AATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPA-TPSLKGAPTP 1082
Query: 202 IGST 205
+T
Sbjct: 1083 PAAT 1086
Score = 43.5 bits (101), Expect = 3e-04
Identities = 44/121 (36%), Positives = 49/121 (40%), Gaps = 23/121 (19%)
Query: 85 KGADGKTKIATPR----GAAPPGQKGQANATRIPAKTPPAPK----TPPSSGEPPKSGD- 135
KGA T ATP G A P KG A PA TPP+PK TPP G P
Sbjct: 1215 KGAP-TTPAATPPSPKGGLATPSPKG---APTTPAATPPSPKGGPATPPPKGAPTPPAAT 1270
Query: 136 ----RSGYSSPGSPGTPGSRSRTPSLPT--PPTREPKKVAVVRTPP-KSPSSAKSRLQTA 188
+ G ++P G P TP P P T PK TPP +P S K T
Sbjct: 1271 PPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAP---TPPAATPPSPKGSPGTP 1327
Query: 189 P 189
P
Sbjct: 1328 P 1328
Score = 41.6 bits (96), Expect = 0.001
Identities = 48/159 (30%), Positives = 59/159 (37%), Gaps = 43/159 (27%)
Query: 85 KGADGKTKIATPR----GAAPPGQKGQANATRIPAKTPPAPK------------TPPSSG 128
KGA T ATP G A P KG A PA TPP+PK T P++
Sbjct: 1169 KGAP-TTPAATPPSPKGGLATPSPKG---APTTPAATPPSPKGGLATPSPKGAPTTPAAT 1224
Query: 129 EPPKSGDRSGYSSPGSPGTPGSRSRTPS----------LPTPPTREPKKV-AVVRTPPK- 176
P G + S G+P TP + +P PTPP P + + TPP
Sbjct: 1225 PPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHK 1284
Query: 177 --------SPSSAKSRLQTAP---VPMPDLKNVKSKIGS 204
+P S K T+P P P S GS
Sbjct: 1285 GAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGS 1323
Score = 39.7 bits (91), Expect = 0.004
Identities = 30/95 (31%), Positives = 41/95 (43%), Gaps = 11/95 (11%)
Query: 98 GAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSP-GSPGTPGSRSRTPS 156
G A P KG +PA TPP+PK EPP + SSP +P TP P+
Sbjct: 1455 GPATPSSKGDPT---LPAVTPPSPK------EPPAPKQVATSSSPKKAPATPAPMG-APT 1504
Query: 157 LPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVP 191
LP PK+V + + P + + L + P
Sbjct: 1505 LPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTP 1539
Score = 39.3 bits (90), Expect = 0.005
Identities = 33/123 (26%), Positives = 46/123 (37%), Gaps = 13/123 (10%)
Query: 82 KKAKGADGKTKIATPRGAAPPGQKGQANATRI---PAKTPPAPKTPPSSGEPPKSGDRSG 138
K+A + ++P P KG + + PA T P+PK P+ G
Sbjct: 1568 KEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKG 1627
Query: 139 YSSPGSPGTPGSRSRTPS----LPTPPTREPKKV------AVVRTPPKSPSSAKSRLQTA 188
++P GTP S TPS PT P K+ A P K +A + A
Sbjct: 1628 PATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVA 1687
Query: 189 PVP 191
P P
Sbjct: 1688 PAP 1690
Score = 37.0 bits (84), Expect = 0.027
Identities = 41/147 (27%), Positives = 57/147 (38%), Gaps = 28/147 (19%)
Query: 95 TPRGAAPPGQKGQANATRIPAKTPPAPKTPPSS-----GEPPKSGDRSGYSSP-GSPGTP 148
TP PP + + AT P TP +P PSS P + G + P S G P
Sbjct: 1615 TPPAVTPPSPE-KGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLP 1673
Query: 149 GSRSRT-----------PSLP--TPPTR---EPKKVAVVRTP----PKSPSSAKSRLQT- 187
+ T S P T PTR + KK + P P + + +K L T
Sbjct: 1674 AKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTV 1733
Query: 188 APVPMPDLKNVKSKIGSTENLKHQPGG 214
AP P+ ++ SK ++ H P G
Sbjct: 1734 APAPLLPVQKDSSKTAKGKDASHSPKG 1760
Score = 36.6 bits (83), Expect = 0.035
Identities = 37/117 (31%), Positives = 48/117 (41%), Gaps = 20/117 (17%)
Query: 93 IATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGE---PPKSGDRSGYSSPGSPG-TP 148
I TP+ A P A+ PA TP K PS E PP S +P P TP
Sbjct: 1564 IPTPKEA--PATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTP 1621
Query: 149 GSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGST 205
S + P+ P P +PP +PSS K T+P +V K+G+T
Sbjct: 1622 PSPEKGPATPAPK-------GTPTSPPVTPSSLKDS-PTSPA------SVTCKMGAT 1664
Score = 32.0 bits (71), Expect = 0.86
Identities = 34/125 (27%), Positives = 47/125 (37%), Gaps = 14/125 (11%)
Query: 84 AKGADGKTKIATPRGA-APPGQKGQANATRIP-AKTPPAPKTPPSSGEPPKSGDRSGYSS 141
+K A GK +P+G APP K T K P P++ S P S
Sbjct: 1746 SKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPS 1805
Query: 142 PGS---------PGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPM 192
P P +PG +PS P P E + + ++ P P S Q+ V M
Sbjct: 1806 PVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLI---PPEPISGGVPFQSVLVNM 1862
Query: 193 PDLKN 197
P K+
Sbjct: 1863 PTPKS 1867
Score = 30.4 bits (67), Expect = 2.5
Identities = 22/88 (25%), Positives = 38/88 (43%), Gaps = 9/88 (10%)
Query: 106 GQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREP 165
G+A T +PA P+ + P S S ++ G PG P+LP P + P
Sbjct: 3 GEATET-VPATEQELPQPQAETAVLPMSSALSVTAALGQPG--------PTLPPPCSPAP 53
Query: 166 KKVAVVRTPPKSPSSAKSRLQTAPVPMP 193
++ + SP + S + + P+ +P
Sbjct: 54 QQCPLSAANQASPFPSPSTIASTPLEVP 81
Score = 29.3 bits (64), Expect = 5.6
Identities = 32/104 (30%), Positives = 41/104 (39%), Gaps = 10/104 (9%)
Query: 90 KTKIATPRGAAPPGQKGQANATRIPAKTPPAPK--TPPSSGEPPKSGDRSGYSSPGSPGT 147
K AT PP KG A A TP +PK T P P S + G P T
Sbjct: 847 KDSPATTHSPTPPSPKG---APTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEG-PAT 902
Query: 148 PGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVP 191
P + + P+L + + PKK P P+S + AP P
Sbjct: 903 PAPK-QAPAL-SMTSSSPKKARATPAPKGIPASPSPK--GAPTP 942
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 48.5 bits (114), Expect = 9e-06
Identities = 44/171 (25%), Positives = 60/171 (35%), Gaps = 11/171 (6%)
Query: 45 AEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPR---GAAP 101
A+ G+G TP+ + A TQ K AK A G TK + G P
Sbjct: 392 AQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAK-APGPTKTPVQQPGPGKIP 450
Query: 102 PGQKG-------QANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRT 154
Q G Q T+ P++ P K PP P K + S+ PGS
Sbjct: 451 AQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPP 510
Query: 155 PSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGST 205
P P P P++ + P + P SAK Q P + + T
Sbjct: 511 PQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQT 561
Score = 45.8 bits (107), Expect = 6e-05
Identities = 42/138 (30%), Positives = 52/138 (37%), Gaps = 27/138 (19%)
Query: 89 GKTKIATPRGAAPPGQK-------GQANATRIPAKTPPAPKTP---PSSGEPPKSGDRSG 138
GKT P A PP Q+ Q + PAK P KTP P G+ P G
Sbjct: 398 GKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPG 457
Query: 139 YSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNV 198
+S G S+ P PP ++P + PP+ P SAK P P
Sbjct: 458 KTSAQQTGPTKPPSQLPGPAKPPPQQP---GPAKPPPQQPGSAKP-----PSQQP----- 504
Query: 199 KSKIGSTENLKHQPGGGK 216
GST+ QPG K
Sbjct: 505 ----GSTKPPPQQPGPAK 518
Score = 40.4 bits (93), Expect = 0.002
Identities = 30/106 (28%), Positives = 47/106 (44%), Gaps = 18/106 (16%)
Query: 99 AAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLP 158
A PG Q+ P K PAP PP+S PPKS +G + P P+
Sbjct: 949 AGQPGPHSQSGPGA-PMKQAPAPSQPPTSQGPPKS---TGQAPP-----------APAKS 993
Query: 159 TPPTREPKKVAVVRTPPK---SPSSAKSRLQTAPVPMPDLKNVKSK 201
P +E K A + PK +P+ ++ + P P+ D K++ ++
Sbjct: 994 IPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAE 1039
Score = 37.7 bits (86), Expect = 0.016
Identities = 54/203 (26%), Positives = 83/203 (40%), Gaps = 29/203 (14%)
Query: 96 PRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPK-SGDRSGYSSPGS--PGT--PGS 150
P A PP Q Q + + P++ P + K PP P K S + G + P S PG+ P +
Sbjct: 484 PGPAKPPPQ--QPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSA 541
Query: 151 RSRTPSLP-----TPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGST 205
+ +P+ P T P + ++ P SPS+ + Q P K + +T
Sbjct: 542 QQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLP------KTICPLCNTT 595
Query: 206 ENLKHQPGGGKVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKI 265
E L H P K + V S CG N H EVK E L +++ +
Sbjct: 596 ELLLHVP--EKANFNTCTECQTTVCSLCGFNPNPH------LTEVK-EWLCLNCQMKRAL 646
Query: 266 GSLDNITHVPGGGNKKIETHKLT 288
G ++ VP K++T +T
Sbjct: 647 GG--DLAPVPSSPQPKLKTAPVT 667
Score = 35.4 bits (80), Expect = 0.077
Identities = 44/178 (24%), Positives = 65/178 (36%), Gaps = 21/178 (11%)
Query: 46 EEAGIGDTPSLEDEAAGHVT--QARMVSKSKDGTGS--DDKKAKGADGKTKIATPRGAAP 101
++ G G P +D ++ Q + GTG K+ R A+
Sbjct: 221 KQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASR 280
Query: 102 PGQKGQANATRIPAKTP--PAPKTPP----SSGEPPKSGDRSGYSSPGSPGTPGSRSRTP 155
P K QA+ R + P P+P PP + G+PP S PG P S
Sbjct: 281 PQTK-QADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPS--- 336
Query: 156 SLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPG 213
L P ++P V+ P + P + K Q P+ K + GS + QPG
Sbjct: 337 GLTKPLAQQP---GTVKPPVQPPGTTKPPAQ----PLGPAKPPAQQTGSEKPSSEQPG 387
Score = 35.0 bits (79), Expect = 0.10
Identities = 58/235 (24%), Positives = 84/235 (35%), Gaps = 47/235 (20%)
Query: 64 VTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKT 123
VT VSKS K + AAP K + P K PP K
Sbjct: 666 VTTTSAVSKSSPQPQQTSPK-------------KDAAP---KQDLSKAPEPKKPPPLVKQ 709
Query: 124 PPSSG-------EPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKV-------- 168
P G +PP++ S + P P P + + P P ++PK V
Sbjct: 710 PTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKP-KQPKMVKPTTDLVS 768
Query: 169 -AVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKV-----QIVYK 222
+ T P PSS K + Q P LK +K + P G KV + + +
Sbjct: 769 SSSATTKPDIPSS-KVQSQAEEKTTPPLKTDSAK----PSQSFPPTGEKVSPFDSKAIPR 823
Query: 223 PVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGG 277
P SK+ S G G QV+ +K + K + Q+K+ + +P G
Sbjct: 824 PASDSKIISHPGPSS---ESKGQKQVDPVQKKEEPK-KAQTKMSPKPDAKPMPKG 874
Score = 34.3 bits (77), Expect = 0.17
Identities = 39/152 (25%), Positives = 57/152 (37%), Gaps = 10/152 (6%)
Query: 100 APPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPT 159
A P ++++ I A+ PP P PP PP P SP + ++ +
Sbjct: 2388 AKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVAS 2447
Query: 160 PPTREPKKVAVVRTPPKSPSSAKSRL------QTAPVPMPDLKNVKSKIGSTENLKHQPG 213
P T V T + + L TAP P+P S I S H+P
Sbjct: 2448 PVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPP---KPSSIPSGLVFTHRPE 2504
Query: 214 GGKVQIVYKPVDLSKVTSKCGSLGNIHHKPGG 245
K I KPV + ++ + +IH KP G
Sbjct: 2505 PSKPPIAPKPV-IPQLPTTTQKPTDIHPKPTG 2535
Score = 33.5 bits (75), Expect = 0.29
Identities = 25/89 (28%), Positives = 37/89 (41%), Gaps = 4/89 (4%)
Query: 101 PPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTP 160
PPG PAK PPA +T + G ++ PG TP + PT
Sbjct: 355 PPGTTKPPAQPLGPAK-PPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQ 413
Query: 161 PTREPKKVAV---VRTPPKSPSSAKSRLQ 186
PK +A +++P K+P K+ +Q
Sbjct: 414 QVGTPKPLAQQPGLQSPAKAPGPTKTPVQ 442
Score = 32.7 bits (73), Expect = 0.50
Identities = 25/105 (23%), Positives = 41/105 (39%), Gaps = 5/105 (4%)
Query: 113 IPAKTPPAPKTPP--SSGEPPKSGDRSGYSSPGSPGTPG---SRSRTPSLPTPPTREPKK 167
+P+ P KT P ++ KS + +SP P S++ P P P ++P
Sbjct: 653 VPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTL 712
Query: 168 VAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQP 212
K P A S + AP P + + + K ++ QP
Sbjct: 713 HGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQP 757
Score = 31.2 bits (69), Expect = 1.5
Identities = 44/163 (26%), Positives = 63/163 (38%), Gaps = 10/163 (6%)
Query: 40 DAGLKAEEAGIGDTPSLEDEAAGHVTQARMVSK-SKDGTGSDDKKAKGADGKTKIATPRG 98
+ ++ E G TPS+ V + +S K G AD T+
Sbjct: 3523 EISVQTEPVGTIRTPSIRARVDAKVEIIKHISAPEKTYKGGSLGCQTEADSDTQSPQYLS 3582
Query: 99 A-APPGQKGQANATRIPAKTP-PAPKTPPSSGEPPKSGDRSGYS--SPGSPGTPGSRSRT 154
A +PP K + I + A T + PPKS + YS SP SPG +
Sbjct: 3583 ATSPPKDKKRPTPLEIGYSSHLRADSTVQLAPSPPKS-PKVLYSPISPLSPGKALESAFV 3641
Query: 155 P-SLPTPPTREPKKVA---VVRTPPKSPSSAKSRLQTAPVPMP 193
P P P P+KV + + PP SP +AK ++ P P
Sbjct: 3642 PYEKPLPDDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDPKP 3684
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 48.5 bits (114), Expect = 9e-06
Identities = 44/171 (25%), Positives = 60/171 (35%), Gaps = 11/171 (6%)
Query: 45 AEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPR---GAAP 101
A+ G+G TP+ + A TQ K AK A G TK + G P
Sbjct: 392 AQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAK-APGPTKTPVQQPGPGKIP 450
Query: 102 PGQKG-------QANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRT 154
Q G Q T+ P++ P K PP P K + S+ PGS
Sbjct: 451 AQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPP 510
Query: 155 PSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGST 205
P P P P++ + P + P SAK Q P + + T
Sbjct: 511 PQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQT 561
Score = 45.8 bits (107), Expect = 6e-05
Identities = 42/138 (30%), Positives = 52/138 (37%), Gaps = 27/138 (19%)
Query: 89 GKTKIATPRGAAPPGQK-------GQANATRIPAKTPPAPKTP---PSSGEPPKSGDRSG 138
GKT P A PP Q+ Q + PAK P KTP P G+ P G
Sbjct: 398 GKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPG 457
Query: 139 YSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNV 198
+S G S+ P PP ++P + PP+ P SAK P P
Sbjct: 458 KTSAQQTGPTKPPSQLPGPAKPPPQQP---GPAKPPPQQPGSAKP-----PSQQP----- 504
Query: 199 KSKIGSTENLKHQPGGGK 216
GST+ QPG K
Sbjct: 505 ----GSTKPPPQQPGPAK 518
Score = 40.4 bits (93), Expect = 0.002
Identities = 30/106 (28%), Positives = 47/106 (44%), Gaps = 18/106 (16%)
Query: 99 AAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLP 158
A PG Q+ P K PAP PP+S PPKS +G + P P+
Sbjct: 949 AGQPGPHSQSGPGA-PMKQAPAPSQPPTSQGPPKS---TGQAPP-----------APAKS 993
Query: 159 TPPTREPKKVAVVRTPPK---SPSSAKSRLQTAPVPMPDLKNVKSK 201
P +E K A + PK +P+ ++ + P P+ D K++ ++
Sbjct: 994 IPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAE 1039
Score = 37.7 bits (86), Expect = 0.016
Identities = 54/203 (26%), Positives = 83/203 (40%), Gaps = 29/203 (14%)
Query: 96 PRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPK-SGDRSGYSSPGS--PGT--PGS 150
P A PP Q Q + + P++ P + K PP P K S + G + P S PG+ P +
Sbjct: 484 PGPAKPPPQ--QPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSA 541
Query: 151 RSRTPSLP-----TPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGST 205
+ +P+ P T P + ++ P SPS+ + Q P K + +T
Sbjct: 542 QQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLP------KTICPLCNTT 595
Query: 206 ENLKHQPGGGKVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKI 265
E L H P K + V S CG N H EVK E L +++ +
Sbjct: 596 ELLLHVP--EKANFNTCTECQTTVCSLCGFNPNPH------LTEVK-EWLCLNCQMKRAL 646
Query: 266 GSLDNITHVPGGGNKKIETHKLT 288
G ++ VP K++T +T
Sbjct: 647 GG--DLAPVPSSPQPKLKTAPVT 667
Score = 35.4 bits (80), Expect = 0.077
Identities = 44/178 (24%), Positives = 65/178 (36%), Gaps = 21/178 (11%)
Query: 46 EEAGIGDTPSLEDEAAGHVT--QARMVSKSKDGTGS--DDKKAKGADGKTKIATPRGAAP 101
++ G G P +D ++ Q + GTG K+ R A+
Sbjct: 221 KQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASR 280
Query: 102 PGQKGQANATRIPAKTP--PAPKTPP----SSGEPPKSGDRSGYSSPGSPGTPGSRSRTP 155
P K QA+ R + P P+P PP + G+PP S PG P S
Sbjct: 281 PQTK-QADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPS--- 336
Query: 156 SLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPG 213
L P ++P V+ P + P + K Q P+ K + GS + QPG
Sbjct: 337 GLTKPLAQQP---GTVKPPVQPPGTTKPPAQ----PLGPAKPPAQQTGSEKPSSEQPG 387
Score = 35.0 bits (79), Expect = 0.10
Identities = 58/235 (24%), Positives = 84/235 (35%), Gaps = 47/235 (20%)
Query: 64 VTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKT 123
VT VSKS K + AAP K + P K PP K
Sbjct: 666 VTTTSAVSKSSPQPQQTSPK-------------KDAAP---KQDLSKAPEPKKPPPLVKQ 709
Query: 124 PPSSG-------EPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKV-------- 168
P G +PP++ S + P P P + + P P ++PK V
Sbjct: 710 PTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKP-KQPKMVKPTTDLVS 768
Query: 169 -AVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKV-----QIVYK 222
+ T P PSS K + Q P LK +K + P G KV + + +
Sbjct: 769 SSSATTKPDIPSS-KVQSQAEEKTTPPLKTDSAK----PSQSFPPTGEKVSPFDSKAIPR 823
Query: 223 PVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGG 277
P SK+ S G G QV+ +K + K + Q+K+ + +P G
Sbjct: 824 PASDSKIISHPGPSS---ESKGQKQVDPVQKKEEPK-KAQTKMSPKPDAKPMPKG 874
Score = 34.3 bits (77), Expect = 0.17
Identities = 39/152 (25%), Positives = 57/152 (37%), Gaps = 10/152 (6%)
Query: 100 APPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPT 159
A P ++++ I A+ PP P PP PP P SP + ++ +
Sbjct: 2388 AKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVAS 2447
Query: 160 PPTREPKKVAVVRTPPKSPSSAKSRL------QTAPVPMPDLKNVKSKIGSTENLKHQPG 213
P T V T + + L TAP P+P S I S H+P
Sbjct: 2448 PVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPP---KPSSIPSGLVFTHRPE 2504
Query: 214 GGKVQIVYKPVDLSKVTSKCGSLGNIHHKPGG 245
K I KPV + ++ + +IH KP G
Sbjct: 2505 PSKPPIAPKPV-IPQLPTTTQKPTDIHPKPTG 2535
Score = 33.5 bits (75), Expect = 0.29
Identities = 25/89 (28%), Positives = 37/89 (41%), Gaps = 4/89 (4%)
Query: 101 PPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTP 160
PPG PAK PPA +T + G ++ PG TP + PT
Sbjct: 355 PPGTTKPPAQPLGPAK-PPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQ 413
Query: 161 PTREPKKVAV---VRTPPKSPSSAKSRLQ 186
PK +A +++P K+P K+ +Q
Sbjct: 414 QVGTPKPLAQQPGLQSPAKAPGPTKTPVQ 442
Score = 32.7 bits (73), Expect = 0.50
Identities = 25/105 (23%), Positives = 41/105 (39%), Gaps = 5/105 (4%)
Query: 113 IPAKTPPAPKTPP--SSGEPPKSGDRSGYSSPGSPGTPG---SRSRTPSLPTPPTREPKK 167
+P+ P KT P ++ KS + +SP P S++ P P P ++P
Sbjct: 653 VPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTL 712
Query: 168 VAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQP 212
K P A S + AP P + + + K ++ QP
Sbjct: 713 HGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQP 757
Score = 31.2 bits (69), Expect = 1.5
Identities = 44/163 (26%), Positives = 63/163 (38%), Gaps = 10/163 (6%)
Query: 40 DAGLKAEEAGIGDTPSLEDEAAGHVTQARMVSK-SKDGTGSDDKKAKGADGKTKIATPRG 98
+ ++ E G TPS+ V + +S K G AD T+
Sbjct: 3523 EISVQTEPVGTIRTPSIRARVDAKVEIIKHISAPEKTYKGGSLGCQTEADSDTQSPQYLS 3582
Query: 99 A-APPGQKGQANATRIPAKTP-PAPKTPPSSGEPPKSGDRSGYS--SPGSPGTPGSRSRT 154
A +PP K + I + A T + PPKS + YS SP SPG +
Sbjct: 3583 ATSPPKDKKRPTPLEIGYSSHLRADSTVQLAPSPPKS-PKVLYSPISPLSPGKALESAFV 3641
Query: 155 P-SLPTPPTREPKKVA---VVRTPPKSPSSAKSRLQTAPVPMP 193
P P P P+KV + + PP SP +AK ++ P P
Sbjct: 3642 PYEKPLPDDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDPKP 3684
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 48.5 bits (114), Expect = 9e-06
Identities = 54/220 (24%), Positives = 81/220 (36%), Gaps = 21/220 (9%)
Query: 9 EVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKAEEAGIGDTPSLEDEAAGHVTQAR 68
E ED G D Q Q+Q+ +D+G + + + P G V + R
Sbjct: 464 ESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSG--SSSSSEDERPKRSHVKNGEVGRRR 521
Query: 69 MVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIP------AKTPPAPK 122
S S+ + S K+ K + + R +PP + + + + P TPP +
Sbjct: 522 RHSPSRSASPSPRKRQKETSPRGR--RRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRR 579
Query: 123 TPPSSGEPPKSGDRSGYSSP----GSPGTPGSRSRTPSLPTPPTRE------PKKVAVVR 172
PS +S YS P SP P R RT S P PP R PK+
Sbjct: 580 RTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKR-RTASPPPPPKRRASPSPPPKRRVSHS 638
Query: 173 TPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQP 212
PPK SS ++ ++ + K + E QP
Sbjct: 639 PPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQP 678
Score = 38.5 bits (88), Expect = 0.009
Identities = 28/149 (18%), Positives = 64/149 (42%), Gaps = 11/149 (7%)
Query: 65 TQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTP 124
++++ S+++ + S + + +++ +PR P ++ P + PP P+
Sbjct: 280 SRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHR 339
Query: 125 PSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTP-----PTREPKKVAVVRTPPK--- 176
S + S S S + SRSR+P P P R+ ++++ +PP+
Sbjct: 340 RSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRH 399
Query: 177 ---SPSSAKSRLQTAPVPMPDLKNVKSKI 202
P++ + + +P P + KS++
Sbjct: 400 RPSPPATPPPKTRHSPTPQQSNRTRKSRV 428
Score = 34.7 bits (78), Expect = 0.13
Identities = 25/84 (29%), Positives = 36/84 (42%), Gaps = 8/84 (9%)
Query: 106 GQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREP 165
G ++++ P K P + PP+ R S SP P R R P+PP P
Sbjct: 357 GSSSSSSSSRSRSPPKKPPKRTSSPPRKTRR--LSPSASP--PRRRHR----PSPPATPP 408
Query: 166 KKVAVVRTPPKSPSSAKSRLQTAP 189
K TP +S + KSR+ +P
Sbjct: 409 PKTRHSPTPQQSNRTRKSRVSVSP 432
Score = 33.5 bits (75), Expect = 0.29
Identities = 35/133 (26%), Positives = 51/133 (38%), Gaps = 30/133 (22%)
Query: 95 TPRGAAPPGQKGQANAT---RIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSP-GTPGS 150
+PR +PP Q+ + + R A PP PK S PPK R +S P +P +
Sbjct: 592 SPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKR--RVSHSPPPKQRSSPVT 649
Query: 151 RSRTPSL---------PTPPTRE---------------PKKVAVVRTPPKSPSSAKSRLQ 186
+ R+PSL P+ TRE P+ +PP A S Q
Sbjct: 650 KRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQ 709
Query: 187 TAPVPMPDLKNVK 199
P P + ++
Sbjct: 710 RRQSPSPSTRPIR 722
Score = 31.2 bits (69), Expect = 1.5
Identities = 21/70 (30%), Positives = 32/70 (45%), Gaps = 2/70 (2%)
Query: 92 KIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSR 151
KI +P + +++ + PA K PP+ P +S S SP P ++
Sbjct: 732 KIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVP-VKKAK 790
Query: 152 SRTPSLPTPP 161
S TPS P+PP
Sbjct: 791 SPTPS-PSPP 799
Score = 30.8 bits (68), Expect = 1.9
Identities = 34/148 (22%), Positives = 57/148 (38%), Gaps = 8/148 (5%)
Query: 53 TPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATR 112
+P + H R +KS+ + + +KK K + + + ++ +
Sbjct: 187 SPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILK 246
Query: 113 IPAKTP-PAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLP---TPPTREPKKV 168
+P P P PK P K ++ + P S SRSRT S T P R +
Sbjct: 247 VPKPEPIPEPKEPSPEKNSKKEKEKEK-TRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSR 305
Query: 169 AVVRTPPKSPSSAK---SRLQTAPVPMP 193
+ +P + PS + R +T P MP
Sbjct: 306 SRSYSPRRRPSPRRRPSPRRRTPPRRMP 333
Score = 29.6 bits (65), Expect = 4.3
Identities = 26/103 (25%), Positives = 39/103 (37%), Gaps = 16/103 (15%)
Query: 108 ANATRIPAKTPPAPKTPPS--------SGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPT 159
++ +R P K PP + P S PP+ R P P TP ++R P
Sbjct: 364 SSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHR-----PSPPATPPPKTRHSPTPQ 418
Query: 160 PPTREPKK---VAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVK 199
R K V+ RT K + + +P P P + V+
Sbjct: 419 QSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVE 461
Score = 28.9 bits (63), Expect = 7.3
Identities = 20/71 (28%), Positives = 28/71 (39%), Gaps = 9/71 (12%)
Query: 68 RMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSS 127
R VS S+ +GS + AK P P Q + PA K+P S
Sbjct: 745 RRVSSSRSVSGSPEPAAK---------KPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPS 795
Query: 128 GEPPKSGDRSG 138
PP++ D+ G
Sbjct: 796 PSPPRNSDQEG 806
>gi|54860079 nadrin isoform 1 [Homo sapiens]
Length = 881
Score = 48.1 bits (113), Expect = 1e-05
Identities = 38/138 (27%), Positives = 51/138 (36%), Gaps = 15/138 (10%)
Query: 49 GIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQA 108
G G P +D + V A + S+ +G + +A + + P AA P
Sbjct: 572 GDGSPPKPKDPVSAAVP-APGRNNSQIASGQNQPQAAAGSHQLSMGQPHNAAGPSPHTLR 630
Query: 109 NATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSL-PTPPTREPKK 167
A + PA PP P PP PG + G+ PSL P PPTR P
Sbjct: 631 RAVKKPAPAPPKPGNPPP-------------GHPGGQSSSGTSQHPPSLSPKPPTRSPSP 677
Query: 168 VAVVRTPPKSPSSAKSRL 185
P SA S+L
Sbjct: 678 PTQHTGQPPGQPSAPSQL 695
Score = 36.2 bits (82), Expect = 0.045
Identities = 30/112 (26%), Positives = 47/112 (41%), Gaps = 8/112 (7%)
Query: 96 PRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTP 155
P A P + G + P +TP P TPP + P S + G+P T ++
Sbjct: 736 PNPMALPSEHGLEQPSHTPPQTPTPPSTPPLGKQNP-SLPAPQTLAGGNPET--AQPHAG 792
Query: 156 SLPTP-PTREPKKVAVVRTPPKSP----SSAKSRLQTAPVPMPDLKNVKSKI 202
+LP P P +P+ V PP+ P + S TAP + + S++
Sbjct: 793 TLPRPRPVPKPRNRPSVPPPPQPPGVHSAGDSSLTNTAPTASKIVTDSNSRV 844
Score = 33.1 bits (74), Expect = 0.38
Identities = 23/86 (26%), Positives = 32/86 (37%), Gaps = 6/86 (6%)
Query: 114 PAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREP--KKVAVV 171
P PP TP +P G + + P G P PTPP+ P K+ +
Sbjct: 714 PPPQPPTQATPLMHTKPNSQGPPNPMALPSEHGLEQPSHTPPQTPTPPSTPPLGKQNPSL 773
Query: 172 RTPPK----SPSSAKSRLQTAPVPMP 193
P +P +A+ T P P P
Sbjct: 774 PAPQTLAGGNPETAQPHAGTLPRPRP 799
Score = 30.4 bits (67), Expect = 2.5
Identities = 31/121 (25%), Positives = 42/121 (34%), Gaps = 16/121 (13%)
Query: 75 DGTGSDDKKAKGADGKTKIATPR-GAAPPGQKG---QANATRIPAKTPPAPKTPPSSGEP 130
+ G + A K A P+ G PPG G + ++ P P P T S
Sbjct: 620 NAAGPSPHTLRRAVKKPAPAPPKPGNPPPGHPGGQSSSGTSQHPPSLSPKPPTRSPSPPT 679
Query: 131 PKSGDRSGYSSPGSPGTPG--SRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTA 188
+G PG P P S R S P + P PP+ P+ A + T
Sbjct: 680 QHTG-----QPPGQPSAPSQLSAPRRYSSSLSPIQAPN-----HPPPQPPTQATPLMHTK 729
Query: 189 P 189
P
Sbjct: 730 P 730
>gi|19913396 smoothelin isoform b [Homo sapiens]
Length = 915
Score = 47.4 bits (111), Expect = 2e-05
Identities = 44/200 (22%), Positives = 76/200 (38%), Gaps = 17/200 (8%)
Query: 14 HAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKAEEAGIGDTPSLEDEAAGH-VTQARMVSK 72
++G G R+D G H+ ++ + + E+ P+ E VT ++ +
Sbjct: 133 YSGRPNSGSREDSKGLAAHRLEQCEVPEREEQEQQAEVSKPTPTPEGTSQDVTTVTLLLR 192
Query: 73 SKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPK 132
+ G+ S + + TP PP + +A + A+ P +P+ PPS PPK
Sbjct: 193 APPGSTSSSPASPSSS-----PTPASPEPPLEPAEAQC--LTAEVPGSPEPPPS---PPK 242
Query: 133 SGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPM 192
+ SP P T G + PK+ ++P + PS K P P
Sbjct: 243 TTSPEPQESPTLPSTEG------QVVNKLLSGPKETPAAQSPTRGPSDTKRADVAGPRPC 296
Query: 193 PDLKNVKSKIGSTENLKHQP 212
+V S +N + P
Sbjct: 297 QRSLSVLSPRQPAQNRESTP 316
>gi|19913394 smoothelin isoform c [Homo sapiens]
Length = 917
Score = 47.4 bits (111), Expect = 2e-05
Identities = 44/200 (22%), Positives = 76/200 (38%), Gaps = 17/200 (8%)
Query: 14 HAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKAEEAGIGDTPSLEDEAAGH-VTQARMVSK 72
++G G R+D G H+ ++ + + E+ P+ E VT ++ +
Sbjct: 133 YSGRPNSGSREDSKGLAAHRLEQCEVPEREEQEQQAEVSKPTPTPEGTSQDVTTVTLLLR 192
Query: 73 SKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPK 132
+ G+ S + + TP PP + +A + A+ P +P+ PPS PPK
Sbjct: 193 APPGSTSSSPASPSSS-----PTPASPEPPLEPAEAQC--LTAEVPGSPEPPPS---PPK 242
Query: 133 SGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPM 192
+ SP P T G + PK+ ++P + PS K P P
Sbjct: 243 TTSPEPQESPTLPSTEG------QVVNKLLSGPKETPAAQSPTRGPSDTKRADVAGPRPC 296
Query: 193 PDLKNVKSKIGSTENLKHQP 212
+V S +N + P
Sbjct: 297 QRSLSVLSPRQPAQNRESTP 316
>gi|47132519 Ras association and pleckstrin homology domains 1
isoform 1 [Homo sapiens]
Length = 1250
Score = 47.0 bits (110), Expect = 3e-05
Identities = 38/115 (33%), Positives = 51/115 (44%), Gaps = 19/115 (16%)
Query: 95 TPRGAAPPGQKGQANATRIPAK-TPPAPKTPPSSGEPPKSGDRSGYSS--PGSPGTP--- 148
TP PP +K A PA PP+P TPP PP + + + P SP +P
Sbjct: 805 TPTPPVPPAKKQPA----FPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPS 860
Query: 149 ---GSRSRTPSLPTPPTRE--PKKVAVVRTPPKSPSSAKSRLQ----TAPVPMPD 194
S+ P PTPP E P K P+SP + K++ + + PVP PD
Sbjct: 861 VVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPD 915
Score = 37.4 bits (85), Expect = 0.020
Identities = 25/81 (30%), Positives = 31/81 (38%), Gaps = 11/81 (13%)
Query: 100 APPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPT 159
AP K A A P P PP+ +P + Y P P TP +P
Sbjct: 787 APTSTKTVAPVVTQAAPPTPTPPVPPAKKQP---AFPASYIPPSPP--------TPPVPV 835
Query: 160 PPTREPKKVAVVRTPPKSPSS 180
PP PK+ + PP SP S
Sbjct: 836 PPPTLPKQQSFCAKPPPSPLS 856
Score = 37.0 bits (84), Expect = 0.027
Identities = 32/111 (28%), Positives = 44/111 (39%), Gaps = 5/111 (4%)
Query: 93 IATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSG-DRSGYSSPGSPGTPGSR 151
+ P PP G A A PA P AP P S PP + + + +P TP
Sbjct: 709 VPPPPPPPPPPTPGSAMAQLKPA--PCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPP 766
Query: 152 SRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTA-PVPMPDLKNVKSK 201
P+ P PP PK + + P + + A Q A P P P + K +
Sbjct: 767 PPIPA-PLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQ 816
Score = 32.0 bits (71), Expect = 0.86
Identities = 25/103 (24%), Positives = 39/103 (37%), Gaps = 13/103 (12%)
Query: 83 KAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSP 142
K K + +P PP + P+ P P PP + P + D+SG
Sbjct: 901 KPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASP--TPDKSG---- 954
Query: 143 GSPGTPGSRSRTPSLPTPPTREPKKVAVVRT------PPKSPS 179
SPG S++ +P PP + ++ + PK PS
Sbjct: 955 -SPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPS 996
Score = 31.6 bits (70), Expect = 1.1
Identities = 41/185 (22%), Positives = 66/185 (35%), Gaps = 49/185 (26%)
Query: 47 EAGIGDTPSLEDEAAGHVTQARMVSKS-----KDGTGSDDKKAKGADG------------ 89
++G+ DT + AGHV +VS K GT ++ +
Sbjct: 555 DSGVSDT-----QPAGHVRSQSIVSSVFSEAWKRGTQLEESSKARMESMNRPYTSLVPPL 609
Query: 90 --KTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSP----- 142
+ KI TP A+ P P PP P PP P +S +G ++P
Sbjct: 610 SPQPKIVTPYTASQPSPPLPPPPP--PPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKY 667
Query: 143 -------GSPGTPGSRSRTPSLPTPPTREPKKVAVV-----------RTPPKSPSSAKSR 184
+ G+ + P+ P ++ K +V PP +P SA ++
Sbjct: 668 STITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQ 727
Query: 185 LQTAP 189
L+ AP
Sbjct: 728 LKPAP 732
Score = 31.2 bits (69), Expect = 1.5
Identities = 27/110 (24%), Positives = 41/110 (37%), Gaps = 8/110 (7%)
Query: 112 RIPAKTPPAPKTPPSSGEP--PKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVA 169
+I ++ PP P P +P P + + S P P + + +P+P P +
Sbjct: 864 QIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPES 923
Query: 170 VVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGS---TENLKHQPGGGK 216
+ PP PS + P P P K GS + PGG K
Sbjct: 924 SLVFPPPPPSPVPA---PPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKK 970
>gi|186928844 Cdc42 GTPase-activating protein [Homo sapiens]
Length = 1444
Score = 47.0 bits (110), Expect = 3e-05
Identities = 49/155 (31%), Positives = 69/155 (44%), Gaps = 23/155 (14%)
Query: 77 TGSDDKKAKGADGKTKIATPRGA-APPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGD 135
TG D+K + + + +GA APP QKG + PA+T +P S E + G
Sbjct: 997 TGWDEKALRSF---REFSGLKGAEAPPNQKGPSGVQPNPAET-----SPISLAEGKELGT 1048
Query: 136 RSGYSSP-----GSPGTPGSRSRTPSL--PTPPTREPKKVAVVRT---PPKSPSSAKSRL 185
G+SSP G PG S+ +PS+ T P P K+ + T PPK + S
Sbjct: 1049 HLGHSSPQIRQGGVPGPESSKESSPSVQDSTSPGEHPAKLQLKSTECGPPKGKNRPSSLN 1108
Query: 186 QTAPVPMPDL---KNVKSKIGSTENLKHQPGGGKV 217
+P+ DL +NV S S +PG KV
Sbjct: 1109 LDPAIPIADLFWFENVAS-FSSPGMQVSEPGDPKV 1142
>gi|19913398 smoothelin isoform a [Homo sapiens]
Length = 940
Score = 47.0 bits (110), Expect = 3e-05
Identities = 44/200 (22%), Positives = 76/200 (38%), Gaps = 17/200 (8%)
Query: 14 HAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKAEEAGIGDTPSLEDEAAGH-VTQARMVSK 72
++G G R+D G H+ ++ + + E+ P+ E VT ++ +
Sbjct: 133 YSGRPNSGSREDSKGLAAHRLEQCEVPEREEQEQQAEVSKPTPTPEGTSQDVTTVTLLLR 192
Query: 73 SKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPK 132
+ G+ S + + TP PP + +A + A+ P +P+ PPS PPK
Sbjct: 193 APPGSTSSSPASPSSS-----PTPASPEPPLEPAEAQC--LTAEVPGSPEPPPS---PPK 242
Query: 133 SGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPM 192
+ SP P T G + PK+ ++P + PS K P P
Sbjct: 243 TTSPEPQESPTLPSTEG------QVVNKLLSGPKETPAAQSPHRGPSDTKRADVAGPRPC 296
Query: 193 PDLKNVKSKIGSTENLKHQP 212
+V S +N + P
Sbjct: 297 QRSLSVLSPRQPAQNRESTP 316
>gi|54860105 nadrin isoform 2 [Homo sapiens]
Length = 803
Score = 46.6 bits (109), Expect = 3e-05
Identities = 32/116 (27%), Positives = 43/116 (37%), Gaps = 14/116 (12%)
Query: 71 SKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEP 130
+ S+ +G + +A + + P AA P A + PA PP P PP
Sbjct: 515 NNSQIASGQNQPQAAAGSHQLSMGQPHNAAGPSPHTLRRAVKKPAPAPPKPGNPPP---- 570
Query: 131 PKSGDRSGYSSPGSPGTPGSRSRTPSL-PTPPTREPKKVAVVRTPPKSPSSAKSRL 185
PG + G+ PSL P PPTR P P SA S+L
Sbjct: 571 ---------GHPGGQSSSGTSQHPPSLSPKPPTRSPSPPTQHTGQPPGQPSAPSQL 617
Score = 36.2 bits (82), Expect = 0.045
Identities = 30/112 (26%), Positives = 47/112 (41%), Gaps = 8/112 (7%)
Query: 96 PRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTP 155
P A P + G + P +TP P TPP + P S + G+P T ++
Sbjct: 658 PNPMALPSEHGLEQPSHTPPQTPTPPSTPPLGKQNP-SLPAPQTLAGGNPET--AQPHAG 714
Query: 156 SLPTP-PTREPKKVAVVRTPPKSP----SSAKSRLQTAPVPMPDLKNVKSKI 202
+LP P P +P+ V PP+ P + S TAP + + S++
Sbjct: 715 TLPRPRPVPKPRNRPSVPPPPQPPGVHSAGDSSLTNTAPTASKIVTDSNSRV 766
Score = 33.1 bits (74), Expect = 0.38
Identities = 23/86 (26%), Positives = 32/86 (37%), Gaps = 6/86 (6%)
Query: 114 PAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREP--KKVAVV 171
P PP TP +P G + + P G P PTPP+ P K+ +
Sbjct: 636 PPPQPPTQATPLMHTKPNSQGPPNPMALPSEHGLEQPSHTPPQTPTPPSTPPLGKQNPSL 695
Query: 172 RTPPK----SPSSAKSRLQTAPVPMP 193
P +P +A+ T P P P
Sbjct: 696 PAPQTLAGGNPETAQPHAGTLPRPRP 721
Score = 30.4 bits (67), Expect = 2.5
Identities = 31/121 (25%), Positives = 42/121 (34%), Gaps = 16/121 (13%)
Query: 75 DGTGSDDKKAKGADGKTKIATPR-GAAPPGQKG---QANATRIPAKTPPAPKTPPSSGEP 130
+ G + A K A P+ G PPG G + ++ P P P T S
Sbjct: 542 NAAGPSPHTLRRAVKKPAPAPPKPGNPPPGHPGGQSSSGTSQHPPSLSPKPPTRSPSPPT 601
Query: 131 PKSGDRSGYSSPGSPGTPG--SRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTA 188
+G PG P P S R S P + P PP+ P+ A + T
Sbjct: 602 QHTG-----QPPGQPSAPSQLSAPRRYSSSLSPIQAPN-----HPPPQPPTQATPLMHTK 651
Query: 189 P 189
P
Sbjct: 652 P 652
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 46.2 bits (108), Expect = 4e-05
Identities = 40/122 (32%), Positives = 55/122 (45%), Gaps = 14/122 (11%)
Query: 80 DDKKAKGADGKTKIATPRGAAPPGQKGQA------NATRIPAKTPPAPK--TPPSSGEPP 131
D A G + +ATP +P G K + AT +PA PP+P TP P
Sbjct: 291 DAAPALGPLSSSPLATP---SPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPS 347
Query: 132 KSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKS-RLQTAPV 190
S S + P P TP S++ PS+ TPP + P + + P + P S S LQ P
Sbjct: 348 PSAPPSLQTLPSPPATPPSQA-PPSMTTPPMQAPPSLQTI-PPIQVPHSLTSPSLQAPPS 405
Query: 191 PM 192
P+
Sbjct: 406 PL 407
Score = 40.0 bits (92), Expect = 0.003
Identities = 30/97 (30%), Positives = 38/97 (39%), Gaps = 5/97 (5%)
Query: 100 APPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGT--PGSRSRTPSL 157
+PP + + P + PPA TPP P G +P SP P S TP
Sbjct: 771 SPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPG-QAPFSPSASLPMSPLATPPP 829
Query: 158 PTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPD 194
PP + V +PP SP+ R P P PD
Sbjct: 830 QAPPVLAAPLLQVPPSPPASPTLQAPR--RPPTPGPD 864
Score = 39.7 bits (91), Expect = 0.004
Identities = 36/103 (34%), Positives = 44/103 (42%), Gaps = 16/103 (15%)
Query: 94 ATPRGAAPPGQ---KGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGS 150
A P AAPP Q A+ P+ TPP P+ PP PP P SP P S
Sbjct: 695 APPSLAAPPLQVPPSPPASPPMSPSATPP-PQAPPPLAAPP-------LQVPPSP--PAS 744
Query: 151 RSRTPSLPTPPTREPKKVAV--VRTPPKSPSSAKSRLQTAPVP 191
+PS TPP R P +A ++ PP P+S P P
Sbjct: 745 PPMSPS-ATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPP 786
Score = 38.9 bits (89), Expect = 0.007
Identities = 31/108 (28%), Positives = 42/108 (38%), Gaps = 10/108 (9%)
Query: 93 IATPRGAAPPGQKGQANATRIPAKTPPAPKT-------PPSSGEPPKSGDRSGYSSPGSP 145
+A P APP + + +P AP P S PP ++ +S P SP
Sbjct: 625 LALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFS-PPPSPPVQAPFSPPASP 683
Query: 146 GTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMP 193
P S S TP PP+ + V +PP SP + S P P
Sbjct: 684 --PVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPP 729
Score = 37.7 bits (86), Expect = 0.016
Identities = 25/83 (30%), Positives = 37/83 (44%), Gaps = 4/83 (4%)
Query: 119 PAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSP 178
PA ++ SS P S RSG S+ G+P P PS P P + + V P K
Sbjct: 237 PASRSLSSSATPLSSPARSGPSARGTPRAPAH----PSQPKPKGLQALRPPQVTPPRKDA 292
Query: 179 SSAKSRLQTAPVPMPDLKNVKSK 201
+ A L ++P+ P K++
Sbjct: 293 APALGPLSSSPLATPSPSGTKAR 315
Score = 37.7 bits (86), Expect = 0.016
Identities = 27/78 (34%), Positives = 34/78 (43%), Gaps = 6/78 (7%)
Query: 114 PAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRT 173
P+ TPP+ + PPS PP S +SP P S S TP PP + V +
Sbjct: 687 PSATPPS-QAPPSLAAPPLQVPPSPPASP-----PMSPSATPPPQAPPPLAAPPLQVPPS 740
Query: 174 PPKSPSSAKSRLQTAPVP 191
PP SP + S VP
Sbjct: 741 PPASPPMSPSATPPPRVP 758
Score = 37.4 bits (85), Expect = 0.020
Identities = 44/148 (29%), Positives = 55/148 (37%), Gaps = 27/148 (18%)
Query: 67 ARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQ---KGQANATRIPAKTPP---- 119
+R +S S S + A G TPR A P Q KG A R P TPP
Sbjct: 239 SRSLSSSATPLSSPARSGPSARG-----TPRAPAHPSQPKPKG-LQALRPPQVTPPRKDA 292
Query: 120 APKTPPSSGEPPKSGDRSGYSS-----PGSPGTPGSRSRTPSLP--TP-------PTREP 165
AP P S P + SG + P + TP + PS P TP P+ P
Sbjct: 293 APALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPP 352
Query: 166 KKVAVVRTPPKSPSSAKSRLQTAPVPMP 193
+ P PS A + T P+ P
Sbjct: 353 SLQTLPSPPATPPSQAPPSMTTPPMQAP 380
Score = 37.4 bits (85), Expect = 0.020
Identities = 34/113 (30%), Positives = 46/113 (40%), Gaps = 24/113 (21%)
Query: 93 IATPRGAAP-PGQKGQANATRIPAKTP-----PAPKTPPSSGEPPKSGDRSGYSSPGSPG 146
+ TP AP P Q + T P +TP P P+ PP+ PP G P P
Sbjct: 558 LETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQG------LPSPPL 611
Query: 147 TPGSRSRTPSLPTPPTREPKKVAV--VRTPPKSPSSAKSRLQTAPVPMPDLKN 197
+P L TPP + P +A+ ++ PP P+S L P P N
Sbjct: 612 SP--------LATPPPQAPPXLALPPLQAPPSPPASPP--LSPLATPSPQAPN 654
Score = 36.6 bits (83), Expect = 0.035
Identities = 35/105 (33%), Positives = 46/105 (43%), Gaps = 8/105 (7%)
Query: 94 ATPRGAAPPGQ---KGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSS-PGSPGTPG 149
A P AAPP Q A+ P+ TPP P+ PP PP S +S P SP
Sbjct: 726 APPPLAAPPLQVPPSPPASPPMSPSATPP-PRVPPLLAAPPLQVPPSPPASLPMSPLAKP 784
Query: 150 SRSRTPSLPTPPTRE-PKKVAVVRTPPKSPSSAKSRLQTAPVPMP 193
P+L TPP + P A P ++P S + L +P+ P
Sbjct: 785 PPQAPPALATPPLQALPSPPA--SFPGQAPFSPSASLPMSPLATP 827
Score = 35.0 bits (79), Expect = 0.10
Identities = 28/102 (27%), Positives = 37/102 (36%), Gaps = 14/102 (13%)
Query: 94 ATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSR 153
ATP APP A ++P P +P PS+ PP++ P +
Sbjct: 689 ATPPSQAPPSLA--APPLQVPPSPPASPPMSPSATPPPQA----------PPPLAAPPLQ 736
Query: 154 TPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDL 195
P P+PP P + P P A LQ P P L
Sbjct: 737 VP--PSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASL 776
Score = 32.0 bits (71), Expect = 0.86
Identities = 26/105 (24%), Positives = 41/105 (39%), Gaps = 8/105 (7%)
Query: 91 TKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGS 150
+ IATP APP P + P+P P + PP++ +P +P +
Sbjct: 585 SSIATPPPQAPPALASP------PLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPA 638
Query: 151 RSRTPSLPTPPTREPKKVAV--VRTPPKSPSSAKSRLQTAPVPMP 193
L TP + P +AV ++ P P S + +P P
Sbjct: 639 SPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP 683
Score = 29.3 bits (64), Expect = 5.6
Identities = 34/123 (27%), Positives = 53/123 (43%), Gaps = 17/123 (13%)
Query: 84 AKGADGKTKIATPRG----AAPPGQKGQANATRIPAKTPPAPKT-PPSSGEPPKSGDRSG 138
A GA G+ +A G A P +A TR + P + PP+SG ++
Sbjct: 49 AAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKN 108
Query: 139 YSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRT---------PPKSPSSAKSRLQTA- 188
+SPG +PG S T + P P ++ +++ T P +S SA +R T+
Sbjct: 109 -TSPGPVSSPGRASGT-TRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSG 166
Query: 189 PVP 191
P P
Sbjct: 167 PTP 169
Score = 28.9 bits (63), Expect = 7.3
Identities = 29/107 (27%), Positives = 40/107 (37%), Gaps = 11/107 (10%)
Query: 94 ATPRGAAPPGQ-----KGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTP 148
ATP APP + + IP P T PS PP S + S G+P
Sbjct: 362 ATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSP 421
Query: 149 GSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSA--KSRLQTAPVPMP 193
++ L T P++ T P P+S S AP+ +P
Sbjct: 422 TLQATHSFL----TMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLP 464
Score = 28.9 bits (63), Expect = 7.3
Identities = 26/103 (25%), Positives = 34/103 (33%), Gaps = 6/103 (5%)
Query: 93 IATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRS 152
+ PR PG + R+ P P PP PP S S P G S +
Sbjct: 852 LQAPRRPPTPGPDTSVSGPRLTLALAPGP--PP----PPSRSPSSTLSGPDLAGHSSSAT 905
Query: 153 RTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDL 195
TP P+ A PP + +A + P P L
Sbjct: 906 STPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPL 948
Score = 28.5 bits (62), Expect = 9.5
Identities = 22/74 (29%), Positives = 31/74 (41%), Gaps = 6/74 (8%)
Query: 120 APKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPS 179
+P+ P SS P +S + P S TP + TP L P+ P + P +P
Sbjct: 499 SPQAPLSSLIMPPLETQSSLAPP-SLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTP- 556
Query: 180 SAKSRLQTAPVPMP 193
L+T P P P
Sbjct: 557 ----HLETPPCPAP 566
>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
Length = 1427
Score = 45.8 bits (107), Expect = 6e-05
Identities = 44/169 (26%), Positives = 68/169 (40%), Gaps = 18/169 (10%)
Query: 35 QEG-DTDAGLKAEEAGIGDTPSLEDEAA---GHVTQARMVSKSKDGTGSDDKKAKGADGK 90
QEG AG E A + T + +E G VT A V ++ D A
Sbjct: 942 QEGMSAVAGFSPEWAALAITVPITEEDGTPEGPVTPATTVHAPEE----PDTAAVRVSTP 997
Query: 91 TKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPK--SGDRSGYSSPGSPGTP 148
+ A+P A P ++ + A +P TP P +P ++ PP+ + + +P P +P
Sbjct: 998 EEPASPAAAVPTPEEPTSPAAAVP--TPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSP 1055
Query: 149 GSRSRTPSLPTPPT------REPKKVAVVRTPPKSPSSAKSRLQTAPVP 191
+ TP PT P EP A P+ P+S + + T P
Sbjct: 1056 AAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEP 1104
Score = 40.8 bits (94), Expect = 0.002
Identities = 27/105 (25%), Positives = 45/105 (42%), Gaps = 10/105 (9%)
Query: 95 TPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPK--SGDRSGYSSPGSPGTPGSRS 152
+P A PP ++ + A +P TP P +P ++ P+ + + +P P +P +
Sbjct: 1028 SPAAAVPPPEEPTSPAAAVP--TPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAV 1085
Query: 153 RTPSLPTPPT------REPKKVAVVRTPPKSPSSAKSRLQTAPVP 191
TP PT P EP A P+ P+S + + T P
Sbjct: 1086 PTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEP 1130
Score = 35.0 bits (79), Expect = 0.10
Identities = 23/102 (22%), Positives = 42/102 (41%), Gaps = 7/102 (6%)
Query: 95 TPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPK--SGDRSGYSSPGSPGTPGSRS 152
+P A P ++ + A +P TP P +P ++ P+ + + +P P +P +
Sbjct: 1080 SPAAAVPTPEEPTSPAAAVP--TPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAV 1137
Query: 153 RTP---SLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVP 191
TP + P P P++ A +P + S P P
Sbjct: 1138 PTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTP 1179
Score = 32.7 bits (73), Expect = 0.50
Identities = 24/95 (25%), Positives = 37/95 (38%), Gaps = 9/95 (9%)
Query: 95 TPRGAAPPGQKGQANATRIP--------AKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPG 146
+P A P ++ + A +P A P P+ P S + + + +P P
Sbjct: 1093 SPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPT 1152
Query: 147 TPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSA 181
S S ++PT P A V TP +S S A
Sbjct: 1153 PEESASAAVAVPT-PEESASPAAAVPTPAESASFA 1186
Score = 30.0 bits (66), Expect = 3.3
Identities = 26/111 (23%), Positives = 43/111 (38%), Gaps = 7/111 (6%)
Query: 94 ATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSR 153
A+P A P ++ + A +P TP P P + P+ + + P TP S
Sbjct: 1118 ASPAAAVPTPEEPASPAAAVP--TPEEPAFPAPAVPTPEESASAAVAVP----TP-EESA 1170
Query: 154 TPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGS 204
+P+ P E A V + P+S + + T + L+ S S
Sbjct: 1171 SPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAAS 1221
Score = 28.9 bits (63), Expect = 7.3
Identities = 25/111 (22%), Positives = 41/111 (36%), Gaps = 13/111 (11%)
Query: 94 ATPRGAAPPGQKGQANATRIPA---KTPPAPKTPPSSGEPPKSGDRSGYSSPGSPG---- 146
A P A P ++ + A +P PA P + + + P SP
Sbjct: 1144 AFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVP 1203
Query: 147 TPGSRSRT------PSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVP 191
TP + T P+ P + EP +A + P+ P+S + + T P
Sbjct: 1204 TPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEP 1254
>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
Length = 1466
Score = 45.4 bits (106), Expect = 7e-05
Identities = 42/143 (29%), Positives = 54/143 (37%), Gaps = 12/143 (8%)
Query: 15 AGTYGLGDRKDQGGYTMHQDQEGDTDA-GLKAEEA--GIGDTPSLEDEAAGHVTQARMVS 71
AG G K G+ ++G+T A GLK E G P + R
Sbjct: 254 AGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGL 313
Query: 72 KSKDGTGSDDKKAKGADGKTKIATPRGAA----PPGQKGQANATRIPAKTPPAPKTPPSS 127
G +D A+G+DG+ P G A PG KG+ PA +P + P
Sbjct: 314 PGAAGARGNDG-ARGSDGQPGPPGPPGTAGFPGSPGAKGEVG----PAGSPGSNGAPGQR 368
Query: 128 GEPPKSGDRSGYSSPGSPGTPGS 150
GEP G PG PG GS
Sbjct: 369 GEPGPQGHAGAQGPPGPPGINGS 391
Score = 43.1 bits (100), Expect = 4e-04
Identities = 33/92 (35%), Positives = 40/92 (43%), Gaps = 11/92 (11%)
Query: 73 SKDGTGSDDKKAK-GADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPP 131
S G GSD K G+ G++ P G P G +GQ P PK + G P
Sbjct: 541 SPGGPGSDGKPGPPGSQGESGRPGPPG--PSGPRGQPGVMGFPG-----PKG--NDGAPG 591
Query: 132 KSGDRSGYSSPGSPGTPGSRSRT-PSLPTPPT 162
K+G+R G PG G PG T P P PT
Sbjct: 592 KNGERGGPGGPGPQGPPGKNGETGPQGPPGPT 623
Score = 40.8 bits (94), Expect = 0.002
Identities = 31/101 (30%), Positives = 39/101 (38%), Gaps = 6/101 (5%)
Query: 81 DKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYS 140
DK GA G IA PRG+ PG++G+ P P P +GEP G+R
Sbjct: 778 DKGEGGAPGLPGIAGPRGS--PGERGETG----PPGPAGFPGAPGQNGEPGGKGERGAPG 831
Query: 141 SPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSA 181
G G PG P+ V R P P +A
Sbjct: 832 EKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAA 872
Score = 40.0 bits (92), Expect = 0.003
Identities = 33/115 (28%), Positives = 41/115 (35%), Gaps = 7/115 (6%)
Query: 82 KKAKGADGKTKIATPRGA-APPGQKGQANATRIPAK--TPPAPKTPPSSGEPPKSGDRSG 138
K G G ++ RG P G G A P + P + P G P GDR
Sbjct: 977 KGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGE 1036
Query: 139 YSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMP 193
SPG+PG PG P P P K + P P+ A + P P
Sbjct: 1037 NGSPGAPGAPGH----PGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGP 1087
Score = 38.5 bits (88), Expect = 0.009
Identities = 43/163 (26%), Positives = 57/163 (34%), Gaps = 18/163 (11%)
Query: 15 AGTYGLGDRKDQGGYTMHQDQEGDTDAGLKAEEAGIGDTPSLEDEAAGHVTQARMVSKSK 74
AG G + G +G+ + EAGI P + E + +
Sbjct: 419 AGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGL 478
Query: 75 DGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPP--APKTPPSSGEPPK 132
G + +GA G A P G PG+KG A P P A P G P
Sbjct: 479 PGAAGE----RGAPGFRGPAGPNGI--PGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGG 532
Query: 133 SGDRS------GYSSPGSPGTPGSRSRT----PSLPTPPTREP 165
G R G S G PG PGS+ + P P+ P +P
Sbjct: 533 PGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQP 575
Score = 36.6 bits (83), Expect = 0.035
Identities = 35/102 (34%), Positives = 39/102 (38%), Gaps = 18/102 (17%)
Query: 78 GSDDKKAKGADGKTKIATPRG----AAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKS 133
G D A G G +A G A PPG +G A P P A TP G P
Sbjct: 673 GKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGP-PGAAGTPGLQGMP--- 728
Query: 134 GDRSGYSSP------GSPGTPGS----RSRTPSLPTPPTREP 165
G+R G SP G PG PG+ P PT P P
Sbjct: 729 GERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPP 770
Score = 35.4 bits (80), Expect = 0.077
Identities = 22/53 (41%), Positives = 26/53 (49%), Gaps = 2/53 (3%)
Query: 111 TRIP-AKTPPAPKTPPSS-GEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPP 161
TR P + P PK P G P ++GD PGSPG+PG S PT P
Sbjct: 96 TRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGP 148
Score = 34.7 bits (78), Expect = 0.13
Identities = 29/94 (30%), Positives = 34/94 (36%), Gaps = 15/94 (15%)
Query: 85 KGADGKTKIATPRG----AAPPGQKGQANATRIPAKTPPA--------PKTPPSSGEPPK 132
KG G +A P G A PPG +G P A P P S+G P
Sbjct: 833 KGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGP 892
Query: 133 SGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPK 166
G SPG G PG T + +P PK
Sbjct: 893 PGPSG---SPGKDGPPGPAGNTGAPGSPGVSGPK 923
Score = 34.7 bits (78), Expect = 0.13
Identities = 52/231 (22%), Positives = 80/231 (34%), Gaps = 46/231 (19%)
Query: 74 KDGT--GSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPA-----PKTPPS 126
+DG+ G D+ G+ G P PPG G A + ++ PA P S
Sbjct: 1024 RDGSPGGKGDRGENGSPGAP--GAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGS 1081
Query: 127 SGEPPKSGDRS-----------------GY-SSPGSPGTPGSRSRTPSLPTPPTREPKKV 168
G P G R G+ +PG+PG+PG + ++ +P P+
Sbjct: 1082 RGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGP 1141
Query: 169 AVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKH--QPGGGKVQIVYKPVDL 226
PP ++ P+ P + + + GS + H QPG P
Sbjct: 1142 VGPSGPPGKDGTSG---HPGPIGPPGPRGNRGERGSEGSPGHPGQPG--------PPGPP 1190
Query: 227 SKVTSKCGSLGNI------HHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNI 271
CG +G K GG E +DFK + SL ++
Sbjct: 1191 GAPGPCCGGVGAAAIAGIGGEKAGGFAPYYGDEPMDFKINTDEIMTSLKSV 1241
Score = 32.3 bits (72), Expect = 0.66
Identities = 19/55 (34%), Positives = 23/55 (41%), Gaps = 4/55 (7%)
Query: 95 TPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPG 149
+P PPG+ GQA P+ P P SG K G+ PG G PG
Sbjct: 196 SPGYQGPPGEPGQAG----PSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPG 246
Score = 32.3 bits (72), Expect = 0.66
Identities = 26/83 (31%), Positives = 33/83 (39%), Gaps = 13/83 (15%)
Query: 84 AKGADGKTKIATPRGA----APPGQKGQANATRIPAKT-PPAPK-TPPSSGEPPKSGDRS 137
A G G + P G+ PPG G P K PP P + G P SG +
Sbjct: 871 AAGFPGARGLPGPPGSNGNPGPPGPSGS------PGKDGPPGPAGNTGAPGSPGVSGPKG 924
Query: 138 GYSSPGSPGTPGSRSRTPSLPTP 160
PG G+PG++ P P P
Sbjct: 925 DAGQPGEKGSPGAQG-PPGAPGP 946
Score = 32.0 bits (71), Expect = 0.86
Identities = 25/74 (33%), Positives = 28/74 (37%), Gaps = 15/74 (20%)
Query: 88 DGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGT 147
D K+ +A A PG G PP P PP + P S GY P PG
Sbjct: 159 DVKSGVAVGGLAGYPGPAG-----------PPGPPGPPGTSGHPGSPGSPGYQGP--PGE 205
Query: 148 PGSRSRTPSLPTPP 161
PG PS P P
Sbjct: 206 PGQAG--PSGPPGP 217
Score = 31.2 bits (69), Expect = 1.5
Identities = 19/51 (37%), Positives = 21/51 (41%), Gaps = 11/51 (21%)
Query: 118 PPAPKTPPSS-------GEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPP 161
P AP PP+ G+P G PG PG PGS P P PP
Sbjct: 92 PTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGS----PGSPGPP 138
Score = 31.2 bits (69), Expect = 1.5
Identities = 27/112 (24%), Positives = 37/112 (33%), Gaps = 20/112 (17%)
Query: 72 KSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKT----------PPAP 121
K DG + + G G P PPG+ G+ P T PP P
Sbjct: 584 KGNDGAPGKNGERGGPGG------PGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGP 637
Query: 122 K----TPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVA 169
+ P + G P ++G G G PG+ P R P +A
Sbjct: 638 QGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLA 689
Score = 31.2 bits (69), Expect = 1.5
Identities = 31/102 (30%), Positives = 37/102 (36%), Gaps = 11/102 (10%)
Query: 81 DKKAKGADGKTKI-ATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGY 139
DK G G + P PPG+ G+ P AP P G+ G+R
Sbjct: 628 DKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPG-PKGDAGAPGAPGGKGDAGAPGER--- 683
Query: 140 SSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSA 181
PG G PG R PP E K A PP P +A
Sbjct: 684 GPPGLAGAPGLRGGA----GPPGPEGGKGAA--GPPGPPGAA 719
Score = 30.8 bits (68), Expect = 1.9
Identities = 32/135 (23%), Positives = 47/135 (34%), Gaps = 17/135 (12%)
Query: 86 GADGKTKIATPRGA----APPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSS 141
G++G P G+ PPG G A P + P +G+P + G
Sbjct: 885 GSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKG----DAGQPGEKGSPGAQGP 940
Query: 142 PGSPGTPGSRSRT--------PSLPTP-PTREPKKVAVVRTPPKSPSSAKSRLQTAPVPM 192
PG+PG G T P +P P + P+ V P + + R P +
Sbjct: 941 PGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGL 1000
Query: 193 PDLKNVKSKIGSTEN 207
P L + G N
Sbjct: 1001 PGLAGTAGEPGRDGN 1015
Score = 30.4 bits (67), Expect = 2.5
Identities = 40/154 (25%), Positives = 52/154 (33%), Gaps = 12/154 (7%)
Query: 16 GTYGLGDRKDQGGYTMHQDQEGDT----DAGLKAEEAGIGDTPSLEDEAAGHVTQARMVS 71
G GL GG + G+ DAG G GD + + + A +
Sbjct: 636 GPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLR 695
Query: 72 KSKDGTGSDDKK-AKGADGKTKIA-TPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGE 129
G + K A G G A TP PG++G + P P P + G
Sbjct: 696 GGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPG-PKGDKGEPGGPGADGV 754
Query: 130 PPKSGDR---SGYSSPGSPGTPGSRSR--TPSLP 158
P K G R PG G PG + P LP
Sbjct: 755 PGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLP 788
Score = 30.4 bits (67), Expect = 2.5
Identities = 22/87 (25%), Positives = 31/87 (35%), Gaps = 10/87 (11%)
Query: 81 DKKAKGADGKTKIATPRGA-APPGQKGQANATRIPAKTPPAPK-TPPSSGEPPKSGDRSG 138
++ + G G RG PPG G PP P +P G P +G+
Sbjct: 862 ERGSPGGPGAAGFPGARGLPGPPGSNGNPG--------PPGPSGSPGKDGPPGPAGNTGA 913
Query: 139 YSSPGSPGTPGSRSRTPSLPTPPTREP 165
SPG G G + +P + P
Sbjct: 914 PGSPGVSGPKGDAGQPGEKGSPGAQGP 940
Score = 29.6 bits (65), Expect = 4.3
Identities = 17/51 (33%), Positives = 19/51 (37%), Gaps = 10/51 (19%)
Query: 96 PRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPG 146
P G P G KG P P P +G+P G SPG PG
Sbjct: 99 PNGQGPQGPKGD----------PGPPGIPGRNGDPGIPGQPGSPGSPGPPG 139
Score = 29.6 bits (65), Expect = 4.3
Identities = 17/54 (31%), Positives = 21/54 (38%), Gaps = 4/54 (7%)
Query: 96 PRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPG 149
P A PPG G + P +P +P G P + G PG PG G
Sbjct: 173 PGPAGPPGPPGPPGTSGHPG----SPGSPGYQGPPGEPGQAGPSGPPGPPGAIG 222
Score = 28.5 bits (62), Expect = 9.5
Identities = 23/83 (27%), Positives = 29/83 (34%), Gaps = 3/83 (3%)
Query: 78 GSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRS 137
G + G G + RG PPG G A + K + GEP G+R
Sbjct: 394 GKGEMGPAGIPGAPGLMGARG--PPGPAGANGAPGLRGGAGEPGKNG-AKGEPGPRGERG 450
Query: 138 GYSSPGSPGTPGSRSRTPSLPTP 160
PG PG G + S P
Sbjct: 451 EAGIPGVPGAKGEDGKDGSPGEP 473
>gi|7662234 rab11-family interacting protein 3 isoform 1 [Homo
sapiens]
Length = 756
Score = 44.3 bits (103), Expect = 2e-04
Identities = 39/114 (34%), Positives = 48/114 (42%), Gaps = 18/114 (15%)
Query: 78 GSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAK-TPPAPKTPPSSGEPPKSGDR 136
G D ++ G D P AA G + A PA P+ P S PP+SG R
Sbjct: 46 GGPDPQSPGLDEPA----PGAAADGGARWSAG----PAPGLEGGPRDPGPSAPPPRSGPR 97
Query: 137 SGYSSPGSPGTPGSRSRTPSLPTPP----TREPKKVAVVRTPPKSPSSAKSRLQ 186
+SP +PG PG RS P P T EP++ P P SA RLQ
Sbjct: 98 GQLASPDAPG-PGPRSEAPLPELDPLFSWTEEPEECG----PASCPESAPFRLQ 146
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.305 0.127 0.359
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,382,097
Number of Sequences: 37866
Number of extensions: 1100031
Number of successful extensions: 15355
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 361
Number of HSP's successfully gapped in prelim test: 1394
Number of HSP's that attempted gapping in prelim test: 6525
Number of HSP's gapped (non-prelim): 6532
length of query: 352
length of database: 18,247,518
effective HSP length: 103
effective length of query: 249
effective length of database: 14,347,320
effective search space: 3572482680
effective search space used: 3572482680
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.