Guide to the Human Genome
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Search of human proteins with 82830428

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|82830428 gon-4-like isoform b [Homo sapiens]
         (1529 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|82830428 gon-4-like isoform b [Homo sapiens]                      3069   0.0  
gi|82830424 gon-4-like isoform a [Homo sapiens]                      2989   0.0  
gi|20986490 YY1-associated protein isoform 3 [Homo sapiens]          1400   0.0  
gi|20986488 YY1-associated protein isoform 2 [Homo sapiens]          1362   0.0  
gi|146219843 Snf2-related CBP activator protein [Homo sapiens]         64   1e-09
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    55   5e-07
gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]        55   7e-07
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     52   6e-06
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    51   8e-06
gi|4759128 solute carrier family 24 (sodium/potassium/calcium ex...    51   8e-06
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    50   1e-05
gi|163965366 nascent polypeptide-associated complex alpha subuni...    50   2e-05
gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax ...    47   1e-04
gi|221139926 NHS-like 1 [Homo sapiens]                                 47   2e-04
gi|117938310 sine oculis binding protein homolog [Homo sapiens]        47   2e-04
gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens]                    46   3e-04
gi|38788333 remodeling and spacing factor 1 [Homo sapiens]             45   4e-04
gi|150378543 MYST histone acetyltransferase (monocytic leukemia)...    45   4e-04
gi|150378463 MYST histone acetyltransferase (monocytic leukemia)...    45   4e-04
gi|150378493 MYST histone acetyltransferase (monocytic leukemia)...    45   4e-04
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          45   5e-04
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]          45   5e-04
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]          45   5e-04
gi|21361639 DIPB protein [Homo sapiens]                                45   7e-04
gi|109637791 transcription factor-like nuclear regulator [Homo s...    45   7e-04
gi|18093112 ABT1-associated protein [Homo sapiens]                     45   7e-04
gi|157738619 smoothelin-like 1 [Homo sapiens]                          45   7e-04
gi|116284392 mucin 2 precursor [Homo sapiens]                          44   0.001
gi|114205399 cyclic nucleotide gated channel beta 1 isoform a [H...    44   0.001
gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]         44   0.001

>gi|82830428 gon-4-like isoform b [Homo sapiens]
          Length = 1529

 Score = 3069 bits (7956), Expect = 0.0
 Identities = 1529/1529 (100%), Positives = 1529/1529 (100%)

Query: 1    MLPCKKRRTTVTESLQHKGNQEENNVDLESAVKPESDQVKDLSSVSLSWDPSHGRVAGFE 60
            MLPCKKRRTTVTESLQHKGNQEENNVDLESAVKPESDQVKDLSSVSLSWDPSHGRVAGFE
Sbjct: 1    MLPCKKRRTTVTESLQHKGNQEENNVDLESAVKPESDQVKDLSSVSLSWDPSHGRVAGFE 60

Query: 61   VQSLQDAGNQLGMEDTSLSSGMLTQNTNVPILEGVDVAISQGITLPSLESFHPLNIHIGK 120
            VQSLQDAGNQLGMEDTSLSSGMLTQNTNVPILEGVDVAISQGITLPSLESFHPLNIHIGK
Sbjct: 61   VQSLQDAGNQLGMEDTSLSSGMLTQNTNVPILEGVDVAISQGITLPSLESFHPLNIHIGK 120

Query: 121  GKLHATGSKRGKKMTLRPGPVTQEDRCDHLTLKEPFSGEPSEEVKEEGGKPQMNSEGEIP 180
            GKLHATGSKRGKKMTLRPGPVTQEDRCDHLTLKEPFSGEPSEEVKEEGGKPQMNSEGEIP
Sbjct: 121  GKLHATGSKRGKKMTLRPGPVTQEDRCDHLTLKEPFSGEPSEEVKEEGGKPQMNSEGEIP 180

Query: 181  SLPSGSQSAKPVSQPRKSTQPDVCASPQEKPLRTLFHQPEEEIEDGGLFIPMEEQDNEES 240
            SLPSGSQSAKPVSQPRKSTQPDVCASPQEKPLRTLFHQPEEEIEDGGLFIPMEEQDNEES
Sbjct: 181  SLPSGSQSAKPVSQPRKSTQPDVCASPQEKPLRTLFHQPEEEIEDGGLFIPMEEQDNEES 240

Query: 241  EKRRKKKKGTKRKRDGRGQEGTLAYDLKLDDMLDRTLEDGAKQHNLTAVNVRNILHEVIT 300
            EKRRKKKKGTKRKRDGRGQEGTLAYDLKLDDMLDRTLEDGAKQHNLTAVNVRNILHEVIT
Sbjct: 241  EKRRKKKKGTKRKRDGRGQEGTLAYDLKLDDMLDRTLEDGAKQHNLTAVNVRNILHEVIT 300

Query: 301  NEHVVAMMKAAISETEDMPMFEPKMTRSKLKEVVEKGVVIPTWNISPIKKANEIKPPQFV 360
            NEHVVAMMKAAISETEDMPMFEPKMTRSKLKEVVEKGVVIPTWNISPIKKANEIKPPQFV
Sbjct: 301  NEHVVAMMKAAISETEDMPMFEPKMTRSKLKEVVEKGVVIPTWNISPIKKANEIKPPQFV 360

Query: 361  DIHLEEDDSSDEEYQPDDEEEDETAEESLLESDVESTASSPRGAKKSRLRQSSEMTETDE 420
            DIHLEEDDSSDEEYQPDDEEEDETAEESLLESDVESTASSPRGAKKSRLRQSSEMTETDE
Sbjct: 361  DIHLEEDDSSDEEYQPDDEEEDETAEESLLESDVESTASSPRGAKKSRLRQSSEMTETDE 420

Query: 421  ESGILSEAEKVTTPAIRHISAEVVPMGPPPPPKPKQTRDSTFMEKLHAVDEELASSPVCM 480
            ESGILSEAEKVTTPAIRHISAEVVPMGPPPPPKPKQTRDSTFMEKLHAVDEELASSPVCM
Sbjct: 421  ESGILSEAEKVTTPAIRHISAEVVPMGPPPPPKPKQTRDSTFMEKLHAVDEELASSPVCM 480

Query: 481  DSFQPMDDSLIAFRTRSKMPLKDVPLGQLEAELQAPDITPDMYDPNTADDEDWKMWLGGL 540
            DSFQPMDDSLIAFRTRSKMPLKDVPLGQLEAELQAPDITPDMYDPNTADDEDWKMWLGGL
Sbjct: 481  DSFQPMDDSLIAFRTRSKMPLKDVPLGQLEAELQAPDITPDMYDPNTADDEDWKMWLGGL 540

Query: 541  MNDDVGNEDEADDDDDPEYNFLEDLDEPDTEDFRTDRAVRITKKEVNELMEELFETFQDE 600
            MNDDVGNEDEADDDDDPEYNFLEDLDEPDTEDFRTDRAVRITKKEVNELMEELFETFQDE
Sbjct: 541  MNDDVGNEDEADDDDDPEYNFLEDLDEPDTEDFRTDRAVRITKKEVNELMEELFETFQDE 600

Query: 601  MGFSNMEDDGPEEEECVAEPRPNFNTPQALRFEEPLANLLNEQHRTVKELFEQLKMKKSS 660
            MGFSNMEDDGPEEEECVAEPRPNFNTPQALRFEEPLANLLNEQHRTVKELFEQLKMKKSS
Sbjct: 601  MGFSNMEDDGPEEEECVAEPRPNFNTPQALRFEEPLANLLNEQHRTVKELFEQLKMKKSS 660

Query: 661  AKQLQEVEKVKPQSEKVHQTLILDPAQRKRLQQQMQQHVQLLTQIHLLATCNPNLNPEAT 720
            AKQLQEVEKVKPQSEKVHQTLILDPAQRKRLQQQMQQHVQLLTQIHLLATCNPNLNPEAT
Sbjct: 661  AKQLQEVEKVKPQSEKVHQTLILDPAQRKRLQQQMQQHVQLLTQIHLLATCNPNLNPEAT 720

Query: 721  TTRIFLKELGTFAQSSIALHHQYNPKFQTLFQPCNLMGAMQLIEDFSTHVSIDCSPHKTV 780
            TTRIFLKELGTFAQSSIALHHQYNPKFQTLFQPCNLMGAMQLIEDFSTHVSIDCSPHKTV
Sbjct: 721  TTRIFLKELGTFAQSSIALHHQYNPKFQTLFQPCNLMGAMQLIEDFSTHVSIDCSPHKTV 780

Query: 781  KKTANEFPCLPKQVAWILATSKVFMYPELLPVCSLKAKNPQDKIVFTKAEDNLLALGLKH 840
            KKTANEFPCLPKQVAWILATSKVFMYPELLPVCSLKAKNPQDKIVFTKAEDNLLALGLKH
Sbjct: 781  KKTANEFPCLPKQVAWILATSKVFMYPELLPVCSLKAKNPQDKIVFTKAEDNLLALGLKH 840

Query: 841  FEGTEFPNPLISKYLLTCKTAHQLTVRIKNLNMNRAPDNIIKFYKKTKQLPVLGKCCEEI 900
            FEGTEFPNPLISKYLLTCKTAHQLTVRIKNLNMNRAPDNIIKFYKKTKQLPVLGKCCEEI
Sbjct: 841  FEGTEFPNPLISKYLLTCKTAHQLTVRIKNLNMNRAPDNIIKFYKKTKQLPVLGKCCEEI 900

Query: 901  QPHQWKPPIEREEHRLPFWLKASLPSIQEELRHMADGAREVGNMTGTTEINSDRSLEKDN 960
            QPHQWKPPIEREEHRLPFWLKASLPSIQEELRHMADGAREVGNMTGTTEINSDRSLEKDN
Sbjct: 901  QPHQWKPPIEREEHRLPFWLKASLPSIQEELRHMADGAREVGNMTGTTEINSDRSLEKDN 960

Query: 961  LELGSESRYPLLLPKGVVLKLKPVATRFPRKAWRQKRSSVLKPLLIQPSPSLQPSFNPGK 1020
            LELGSESRYPLLLPKGVVLKLKPVATRFPRKAWRQKRSSVLKPLLIQPSPSLQPSFNPGK
Sbjct: 961  LELGSESRYPLLLPKGVVLKLKPVATRFPRKAWRQKRSSVLKPLLIQPSPSLQPSFNPGK 1020

Query: 1021 TPARSTHSEAPPSKMVLRIPHPIQPATVLQTVPGVPPLGVSGGESFESPAALPAVPPEAR 1080
            TPARSTHSEAPPSKMVLRIPHPIQPATVLQTVPGVPPLGVSGGESFESPAALPAVPPEAR
Sbjct: 1021 TPARSTHSEAPPSKMVLRIPHPIQPATVLQTVPGVPPLGVSGGESFESPAALPAVPPEAR 1080

Query: 1081 TSFPLSESQTLLSSAPVPKVMLPSLAPSKFRKPYVRRRPSKRRGVKASPCMKPAPVIHHP 1140
            TSFPLSESQTLLSSAPVPKVMLPSLAPSKFRKPYVRRRPSKRRGVKASPCMKPAPVIHHP
Sbjct: 1081 TSFPLSESQTLLSSAPVPKVMLPSLAPSKFRKPYVRRRPSKRRGVKASPCMKPAPVIHHP 1140

Query: 1141 ASVIFTVPATTVKIVSLGGGCNMIQPVNAAVAQSPQTIPITTLLVNPTSFPCPLNQSLVA 1200
            ASVIFTVPATTVKIVSLGGGCNMIQPVNAAVAQSPQTIPITTLLVNPTSFPCPLNQSLVA
Sbjct: 1141 ASVIFTVPATTVKIVSLGGGCNMIQPVNAAVAQSPQTIPITTLLVNPTSFPCPLNQSLVA 1200

Query: 1201 SSVSPLIVSGNSVNLPIPSTPEDKAHVNVDIACAVADGENAFQGLEPKLEPQELSPLSAT 1260
            SSVSPLIVSGNSVNLPIPSTPEDKAHVNVDIACAVADGENAFQGLEPKLEPQELSPLSAT
Sbjct: 1201 SSVSPLIVSGNSVNLPIPSTPEDKAHVNVDIACAVADGENAFQGLEPKLEPQELSPLSAT 1260

Query: 1261 VFPKVEHSPGPPLADAECQEGLSENSACRWTVVKTEEGRQALEPLPQGIQESLNNPTPGD 1320
            VFPKVEHSPGPPLADAECQEGLSENSACRWTVVKTEEGRQALEPLPQGIQESLNNPTPGD
Sbjct: 1261 VFPKVEHSPGPPLADAECQEGLSENSACRWTVVKTEEGRQALEPLPQGIQESLNNPTPGD 1320

Query: 1321 LEEIVKMEPEEAREEISGSPERDICDDIKVEHAVELDTGAPSEELSSAGEVTKQTVLQKE 1380
            LEEIVKMEPEEAREEISGSPERDICDDIKVEHAVELDTGAPSEELSSAGEVTKQTVLQKE
Sbjct: 1321 LEEIVKMEPEEAREEISGSPERDICDDIKVEHAVELDTGAPSEELSSAGEVTKQTVLQKE 1380

Query: 1381 EERSQPTKTPSSSQEPPDEGTSGTDVNKGSSKNALSSMDPEVRLSSPPGKPEDSSSVDGQ 1440
            EERSQPTKTPSSSQEPPDEGTSGTDVNKGSSKNALSSMDPEVRLSSPPGKPEDSSSVDGQ
Sbjct: 1381 EERSQPTKTPSSSQEPPDEGTSGTDVNKGSSKNALSSMDPEVRLSSPPGKPEDSSSVDGQ 1440

Query: 1441 SVGTPVGPETGGEKNGPEEEEEEDFDDLTQDEEDEMSSASEESVLSVPELQVRAGEYSQV 1500
            SVGTPVGPETGGEKNGPEEEEEEDFDDLTQDEEDEMSSASEESVLSVPELQVRAGEYSQV
Sbjct: 1441 SVGTPVGPETGGEKNGPEEEEEEDFDDLTQDEEDEMSSASEESVLSVPELQVRAGEYSQV 1500

Query: 1501 FRGLSNMYHLLICHLLACCTMDSPKIICI 1529
            FRGLSNMYHLLICHLLACCTMDSPKIICI
Sbjct: 1501 FRGLSNMYHLLICHLLACCTMDSPKIICI 1529


>gi|82830424 gon-4-like isoform a [Homo sapiens]
          Length = 2240

 Score = 2989 bits (7749), Expect = 0.0
 Identities = 1491/1491 (100%), Positives = 1491/1491 (100%)

Query: 1    MLPCKKRRTTVTESLQHKGNQEENNVDLESAVKPESDQVKDLSSVSLSWDPSHGRVAGFE 60
            MLPCKKRRTTVTESLQHKGNQEENNVDLESAVKPESDQVKDLSSVSLSWDPSHGRVAGFE
Sbjct: 1    MLPCKKRRTTVTESLQHKGNQEENNVDLESAVKPESDQVKDLSSVSLSWDPSHGRVAGFE 60

Query: 61   VQSLQDAGNQLGMEDTSLSSGMLTQNTNVPILEGVDVAISQGITLPSLESFHPLNIHIGK 120
            VQSLQDAGNQLGMEDTSLSSGMLTQNTNVPILEGVDVAISQGITLPSLESFHPLNIHIGK
Sbjct: 61   VQSLQDAGNQLGMEDTSLSSGMLTQNTNVPILEGVDVAISQGITLPSLESFHPLNIHIGK 120

Query: 121  GKLHATGSKRGKKMTLRPGPVTQEDRCDHLTLKEPFSGEPSEEVKEEGGKPQMNSEGEIP 180
            GKLHATGSKRGKKMTLRPGPVTQEDRCDHLTLKEPFSGEPSEEVKEEGGKPQMNSEGEIP
Sbjct: 121  GKLHATGSKRGKKMTLRPGPVTQEDRCDHLTLKEPFSGEPSEEVKEEGGKPQMNSEGEIP 180

Query: 181  SLPSGSQSAKPVSQPRKSTQPDVCASPQEKPLRTLFHQPEEEIEDGGLFIPMEEQDNEES 240
            SLPSGSQSAKPVSQPRKSTQPDVCASPQEKPLRTLFHQPEEEIEDGGLFIPMEEQDNEES
Sbjct: 181  SLPSGSQSAKPVSQPRKSTQPDVCASPQEKPLRTLFHQPEEEIEDGGLFIPMEEQDNEES 240

Query: 241  EKRRKKKKGTKRKRDGRGQEGTLAYDLKLDDMLDRTLEDGAKQHNLTAVNVRNILHEVIT 300
            EKRRKKKKGTKRKRDGRGQEGTLAYDLKLDDMLDRTLEDGAKQHNLTAVNVRNILHEVIT
Sbjct: 241  EKRRKKKKGTKRKRDGRGQEGTLAYDLKLDDMLDRTLEDGAKQHNLTAVNVRNILHEVIT 300

Query: 301  NEHVVAMMKAAISETEDMPMFEPKMTRSKLKEVVEKGVVIPTWNISPIKKANEIKPPQFV 360
            NEHVVAMMKAAISETEDMPMFEPKMTRSKLKEVVEKGVVIPTWNISPIKKANEIKPPQFV
Sbjct: 301  NEHVVAMMKAAISETEDMPMFEPKMTRSKLKEVVEKGVVIPTWNISPIKKANEIKPPQFV 360

Query: 361  DIHLEEDDSSDEEYQPDDEEEDETAEESLLESDVESTASSPRGAKKSRLRQSSEMTETDE 420
            DIHLEEDDSSDEEYQPDDEEEDETAEESLLESDVESTASSPRGAKKSRLRQSSEMTETDE
Sbjct: 361  DIHLEEDDSSDEEYQPDDEEEDETAEESLLESDVESTASSPRGAKKSRLRQSSEMTETDE 420

Query: 421  ESGILSEAEKVTTPAIRHISAEVVPMGPPPPPKPKQTRDSTFMEKLHAVDEELASSPVCM 480
            ESGILSEAEKVTTPAIRHISAEVVPMGPPPPPKPKQTRDSTFMEKLHAVDEELASSPVCM
Sbjct: 421  ESGILSEAEKVTTPAIRHISAEVVPMGPPPPPKPKQTRDSTFMEKLHAVDEELASSPVCM 480

Query: 481  DSFQPMDDSLIAFRTRSKMPLKDVPLGQLEAELQAPDITPDMYDPNTADDEDWKMWLGGL 540
            DSFQPMDDSLIAFRTRSKMPLKDVPLGQLEAELQAPDITPDMYDPNTADDEDWKMWLGGL
Sbjct: 481  DSFQPMDDSLIAFRTRSKMPLKDVPLGQLEAELQAPDITPDMYDPNTADDEDWKMWLGGL 540

Query: 541  MNDDVGNEDEADDDDDPEYNFLEDLDEPDTEDFRTDRAVRITKKEVNELMEELFETFQDE 600
            MNDDVGNEDEADDDDDPEYNFLEDLDEPDTEDFRTDRAVRITKKEVNELMEELFETFQDE
Sbjct: 541  MNDDVGNEDEADDDDDPEYNFLEDLDEPDTEDFRTDRAVRITKKEVNELMEELFETFQDE 600

Query: 601  MGFSNMEDDGPEEEECVAEPRPNFNTPQALRFEEPLANLLNEQHRTVKELFEQLKMKKSS 660
            MGFSNMEDDGPEEEECVAEPRPNFNTPQALRFEEPLANLLNEQHRTVKELFEQLKMKKSS
Sbjct: 601  MGFSNMEDDGPEEEECVAEPRPNFNTPQALRFEEPLANLLNEQHRTVKELFEQLKMKKSS 660

Query: 661  AKQLQEVEKVKPQSEKVHQTLILDPAQRKRLQQQMQQHVQLLTQIHLLATCNPNLNPEAT 720
            AKQLQEVEKVKPQSEKVHQTLILDPAQRKRLQQQMQQHVQLLTQIHLLATCNPNLNPEAT
Sbjct: 661  AKQLQEVEKVKPQSEKVHQTLILDPAQRKRLQQQMQQHVQLLTQIHLLATCNPNLNPEAT 720

Query: 721  TTRIFLKELGTFAQSSIALHHQYNPKFQTLFQPCNLMGAMQLIEDFSTHVSIDCSPHKTV 780
            TTRIFLKELGTFAQSSIALHHQYNPKFQTLFQPCNLMGAMQLIEDFSTHVSIDCSPHKTV
Sbjct: 721  TTRIFLKELGTFAQSSIALHHQYNPKFQTLFQPCNLMGAMQLIEDFSTHVSIDCSPHKTV 780

Query: 781  KKTANEFPCLPKQVAWILATSKVFMYPELLPVCSLKAKNPQDKIVFTKAEDNLLALGLKH 840
            KKTANEFPCLPKQVAWILATSKVFMYPELLPVCSLKAKNPQDKIVFTKAEDNLLALGLKH
Sbjct: 781  KKTANEFPCLPKQVAWILATSKVFMYPELLPVCSLKAKNPQDKIVFTKAEDNLLALGLKH 840

Query: 841  FEGTEFPNPLISKYLLTCKTAHQLTVRIKNLNMNRAPDNIIKFYKKTKQLPVLGKCCEEI 900
            FEGTEFPNPLISKYLLTCKTAHQLTVRIKNLNMNRAPDNIIKFYKKTKQLPVLGKCCEEI
Sbjct: 841  FEGTEFPNPLISKYLLTCKTAHQLTVRIKNLNMNRAPDNIIKFYKKTKQLPVLGKCCEEI 900

Query: 901  QPHQWKPPIEREEHRLPFWLKASLPSIQEELRHMADGAREVGNMTGTTEINSDRSLEKDN 960
            QPHQWKPPIEREEHRLPFWLKASLPSIQEELRHMADGAREVGNMTGTTEINSDRSLEKDN
Sbjct: 901  QPHQWKPPIEREEHRLPFWLKASLPSIQEELRHMADGAREVGNMTGTTEINSDRSLEKDN 960

Query: 961  LELGSESRYPLLLPKGVVLKLKPVATRFPRKAWRQKRSSVLKPLLIQPSPSLQPSFNPGK 1020
            LELGSESRYPLLLPKGVVLKLKPVATRFPRKAWRQKRSSVLKPLLIQPSPSLQPSFNPGK
Sbjct: 961  LELGSESRYPLLLPKGVVLKLKPVATRFPRKAWRQKRSSVLKPLLIQPSPSLQPSFNPGK 1020

Query: 1021 TPARSTHSEAPPSKMVLRIPHPIQPATVLQTVPGVPPLGVSGGESFESPAALPAVPPEAR 1080
            TPARSTHSEAPPSKMVLRIPHPIQPATVLQTVPGVPPLGVSGGESFESPAALPAVPPEAR
Sbjct: 1021 TPARSTHSEAPPSKMVLRIPHPIQPATVLQTVPGVPPLGVSGGESFESPAALPAVPPEAR 1080

Query: 1081 TSFPLSESQTLLSSAPVPKVMLPSLAPSKFRKPYVRRRPSKRRGVKASPCMKPAPVIHHP 1140
            TSFPLSESQTLLSSAPVPKVMLPSLAPSKFRKPYVRRRPSKRRGVKASPCMKPAPVIHHP
Sbjct: 1081 TSFPLSESQTLLSSAPVPKVMLPSLAPSKFRKPYVRRRPSKRRGVKASPCMKPAPVIHHP 1140

Query: 1141 ASVIFTVPATTVKIVSLGGGCNMIQPVNAAVAQSPQTIPITTLLVNPTSFPCPLNQSLVA 1200
            ASVIFTVPATTVKIVSLGGGCNMIQPVNAAVAQSPQTIPITTLLVNPTSFPCPLNQSLVA
Sbjct: 1141 ASVIFTVPATTVKIVSLGGGCNMIQPVNAAVAQSPQTIPITTLLVNPTSFPCPLNQSLVA 1200

Query: 1201 SSVSPLIVSGNSVNLPIPSTPEDKAHVNVDIACAVADGENAFQGLEPKLEPQELSPLSAT 1260
            SSVSPLIVSGNSVNLPIPSTPEDKAHVNVDIACAVADGENAFQGLEPKLEPQELSPLSAT
Sbjct: 1201 SSVSPLIVSGNSVNLPIPSTPEDKAHVNVDIACAVADGENAFQGLEPKLEPQELSPLSAT 1260

Query: 1261 VFPKVEHSPGPPLADAECQEGLSENSACRWTVVKTEEGRQALEPLPQGIQESLNNPTPGD 1320
            VFPKVEHSPGPPLADAECQEGLSENSACRWTVVKTEEGRQALEPLPQGIQESLNNPTPGD
Sbjct: 1261 VFPKVEHSPGPPLADAECQEGLSENSACRWTVVKTEEGRQALEPLPQGIQESLNNPTPGD 1320

Query: 1321 LEEIVKMEPEEAREEISGSPERDICDDIKVEHAVELDTGAPSEELSSAGEVTKQTVLQKE 1380
            LEEIVKMEPEEAREEISGSPERDICDDIKVEHAVELDTGAPSEELSSAGEVTKQTVLQKE
Sbjct: 1321 LEEIVKMEPEEAREEISGSPERDICDDIKVEHAVELDTGAPSEELSSAGEVTKQTVLQKE 1380

Query: 1381 EERSQPTKTPSSSQEPPDEGTSGTDVNKGSSKNALSSMDPEVRLSSPPGKPEDSSSVDGQ 1440
            EERSQPTKTPSSSQEPPDEGTSGTDVNKGSSKNALSSMDPEVRLSSPPGKPEDSSSVDGQ
Sbjct: 1381 EERSQPTKTPSSSQEPPDEGTSGTDVNKGSSKNALSSMDPEVRLSSPPGKPEDSSSVDGQ 1440

Query: 1441 SVGTPVGPETGGEKNGPEEEEEEDFDDLTQDEEDEMSSASEESVLSVPELQ 1491
            SVGTPVGPETGGEKNGPEEEEEEDFDDLTQDEEDEMSSASEESVLSVPELQ
Sbjct: 1441 SVGTPVGPETGGEKNGPEEEEEEDFDDLTQDEEDEMSSASEESVLSVPELQ 1491


>gi|20986490 YY1-associated protein isoform 3 [Homo sapiens]
          Length = 750

 Score = 1400 bits (3625), Expect = 0.0
 Identities = 698/749 (93%), Positives = 720/749 (96%), Gaps = 1/749 (0%)

Query: 590  MEELFETFQDEMGFSNMEDDGPEEEECVAEPRPNFNTPQALRFEEPLANLLNEQHRTVKE 649
            ME+LFETFQDEMGFSNMEDDGPEEEE VAEP+ NFNTPQALRFEE LANLLNEQH+  KE
Sbjct: 1    MEDLFETFQDEMGFSNMEDDGPEEEERVAEPQANFNTPQALRFEELLANLLNEQHQIAKE 60

Query: 650  LFEQLKMKKSSAKQLQEVEKVKPQSEKVHQTLILDPAQRKRLQQQMQQHVQLLTQIHLLA 709
            LFEQLKMKK SAKQ +EVEKVKPQ ++VHQTLILDPAQRKRLQQQMQQHVQLLTQIHLLA
Sbjct: 61   LFEQLKMKKPSAKQQKEVEKVKPQCKEVHQTLILDPAQRKRLQQQMQQHVQLLTQIHLLA 120

Query: 710  TCNPNLNPEATTTRIFLKELGTFAQSSIALHHQYNPKFQTLFQPCNLMGAMQLIEDFSTH 769
            TCNPNLNPEA++TRI LKELGTFAQSSIALHHQYNPKFQTLFQPCNLMGAMQLIEDFSTH
Sbjct: 121  TCNPNLNPEASSTRICLKELGTFAQSSIALHHQYNPKFQTLFQPCNLMGAMQLIEDFSTH 180

Query: 770  VSIDCSPHKTVKKTANEFPCLPKQVAWILATSKVFMYPELLPVCSLKAKNPQDKIVFTKA 829
            VSIDCSPHKTVKKTANEFPCLPKQVAWILATSKVFMYPELLPVCSLKAKNPQDKI+FTKA
Sbjct: 181  VSIDCSPHKTVKKTANEFPCLPKQVAWILATSKVFMYPELLPVCSLKAKNPQDKILFTKA 240

Query: 830  EDNLLALGLKHFEGTEFPNPLISKYLLTCKTAHQLTVRIKNLNMNRAPDNIIKFYKKTKQ 889
            EDNLLALGLKHFEGTEF NPLISKYLLTCKTA QLTVRIKNLNMNRAPDNIIKFYKKTKQ
Sbjct: 241  EDNLLALGLKHFEGTEFLNPLISKYLLTCKTARQLTVRIKNLNMNRAPDNIIKFYKKTKQ 300

Query: 890  LPVLGKCCEEIQPHQWKPPIEREEHRLPFWLKASLPSIQEELRHMADGAREVGNMTGTTE 949
            LPVLGKCCEEIQPHQWKPPIEREEHRLPFWLKASLPSIQEELRHMADGAREVGNMTGTTE
Sbjct: 301  LPVLGKCCEEIQPHQWKPPIEREEHRLPFWLKASLPSIQEELRHMADGAREVGNMTGTTE 360

Query: 950  INSDRSLEKDNLELGSESRYPLLLPKGVVLKLKPVATRFPRKAWRQKRSSVLKPLLIQPS 1009
            INSD+ LEKDN ELGSE+RYPLLLPKGVVLKLKPVA RFP+KAWRQKRSSVLKPLLIQPS
Sbjct: 361  INSDQGLEKDNSELGSETRYPLLLPKGVVLKLKPVADRFPKKAWRQKRSSVLKPLLIQPS 420

Query: 1010 PSLQPSFNPGKTPARSTHSEAPPSKMVLRIPHPIQPATVLQTVPGVPPLGVSGGESFESP 1069
            PSLQPSFNPGKTPA+STHSEAPPSKMVLRIPHPIQPATVLQTVPGVPPLGVSGGESFESP
Sbjct: 421  PSLQPSFNPGKTPAQSTHSEAPPSKMVLRIPHPIQPATVLQTVPGVPPLGVSGGESFESP 480

Query: 1070 AALPAVPPEARTSFPLSESQTLLSSAPVPKVMLPSLAPSKFRKPYVRRRPSKRRGVKASP 1129
            AALPA+PPEARTSFPLSESQTLLSSAPVPKVM+PS A S FRKPYVRRRPSKRRG +A  
Sbjct: 481  AALPAMPPEARTSFPLSESQTLLSSAPVPKVMMPSPASSMFRKPYVRRRPSKRRGARAFR 540

Query: 1130 CMKPAPVIHHPASVIFTVPATTVKIVSLGGGCNMIQPVNAAVAQSPQTIPITTLLVNPTS 1189
            C+KPAPVI HPASVIFTVPATTVKIVSLGGGCNMIQPVNAAVAQSPQTIPI TLLVNPTS
Sbjct: 541  CIKPAPVI-HPASVIFTVPATTVKIVSLGGGCNMIQPVNAAVAQSPQTIPIATLLVNPTS 599

Query: 1190 FPCPLNQSLVASSVSPLIVSGNSVNLPIPSTPEDKAHVNVDIACAVADGENAFQGLEPKL 1249
            FPCPLNQ LVASSVSPLIVSGNSVNLPIPSTPEDKAH+NVDIACAVADGENAFQGLEPKL
Sbjct: 600  FPCPLNQPLVASSVSPLIVSGNSVNLPIPSTPEDKAHMNVDIACAVADGENAFQGLEPKL 659

Query: 1250 EPQELSPLSATVFPKVEHSPGPPLADAECQEGLSENSACRWTVVKTEEGRQALEPLPQGI 1309
            EPQELSPLSATVFPKVEHSPGPP  D +CQEGLSENSA RWTVVKTEEGRQALEPLPQGI
Sbjct: 660  EPQELSPLSATVFPKVEHSPGPPPVDKQCQEGLSENSAYRWTVVKTEEGRQALEPLPQGI 719

Query: 1310 QESLNNPTPGDLEEIVKMEPEEAREEISG 1338
            QESLNN +PGDLEE+VKMEPE+A EEISG
Sbjct: 720  QESLNNSSPGDLEEVVKMEPEDATEEISG 748


>gi|20986488 YY1-associated protein isoform 2 [Homo sapiens]
          Length = 796

 Score = 1362 bits (3526), Expect = 0.0
 Identities = 684/756 (90%), Positives = 707/756 (93%), Gaps = 21/756 (2%)

Query: 583  KKEVNELMEELFETFQDEMGFSNMEDDGPEEEECVAEPRPNFNTPQALRFEEPLANLLNE 642
            +KE NELME+LFETFQDEMGFSNMEDDGPEEEE VAEP+ NFNTPQALRFEE LANLLNE
Sbjct: 60   EKEANELMEDLFETFQDEMGFSNMEDDGPEEEERVAEPQANFNTPQALRFEELLANLLNE 119

Query: 643  QHRTVKELFEQLKMKKSSAKQLQEVEKVKPQSEKVHQTLILDPAQRKRLQQQMQQHVQLL 702
            QH+  KELFEQLKMKK SAKQ +EVEKVKPQ ++VHQTLILDPAQRKRLQQQMQQHVQLL
Sbjct: 120  QHQIAKELFEQLKMKKPSAKQQKEVEKVKPQCKEVHQTLILDPAQRKRLQQQMQQHVQLL 179

Query: 703  TQIHLLATCNPNLNPEATTTRIFLKELGTFAQSSIALHHQYNPKFQTLFQPCNLMGAMQL 762
            TQIHLLATCNPNLNPEA++TRI LKELGTFAQSSIALHHQYNPKFQTLFQPCNLMGAMQL
Sbjct: 180  TQIHLLATCNPNLNPEASSTRICLKELGTFAQSSIALHHQYNPKFQTLFQPCNLMGAMQL 239

Query: 763  IEDFSTHVSIDCSPHKTVKKTANEFPCLPKQVAWILATSKVFMYPELLPVCSLKAKNPQD 822
            IEDFSTHVSIDCSPHKTVKKTANEFPCLPKQVAWILATSKVFMYPELLPVCSLKAKNPQD
Sbjct: 240  IEDFSTHVSIDCSPHKTVKKTANEFPCLPKQVAWILATSKVFMYPELLPVCSLKAKNPQD 299

Query: 823  KIVFTKAEDNLLALGLKHFEGTEFPNPLISKYLLTCKTAHQLTVRIKNLNMNRAPDNIIK 882
            KI+FTKAEDN                    KYLLTCKTA QLTVRIKNLNMNRAPDNIIK
Sbjct: 300  KILFTKAEDN--------------------KYLLTCKTARQLTVRIKNLNMNRAPDNIIK 339

Query: 883  FYKKTKQLPVLGKCCEEIQPHQWKPPIEREEHRLPFWLKASLPSIQEELRHMADGAREVG 942
            FYKKTKQLPVLGKCCEEIQPHQWKPPIEREEHRLPFWLKASLPSIQEELRHMADGAREVG
Sbjct: 340  FYKKTKQLPVLGKCCEEIQPHQWKPPIEREEHRLPFWLKASLPSIQEELRHMADGAREVG 399

Query: 943  NMTGTTEINSDRSLEKDNLELGSESRYPLLLPKGVVLKLKPVATRFPRKAWRQKRSSVLK 1002
            NMTGTTEINSD+ LEKDN ELGSE+RYPLLLPKGVVLKLKPVA RFP+KAWRQKRSSVLK
Sbjct: 400  NMTGTTEINSDQGLEKDNSELGSETRYPLLLPKGVVLKLKPVADRFPKKAWRQKRSSVLK 459

Query: 1003 PLLIQPSPSLQPSFNPGKTPARSTHSEAPPSKMVLRIPHPIQPATVLQTVPGVPPLGVSG 1062
            PLLIQPSPSLQPSFNPGKTPA+STHSEAPPSKMVLRIPHPIQPATVLQTVPGVPPLGVSG
Sbjct: 460  PLLIQPSPSLQPSFNPGKTPAQSTHSEAPPSKMVLRIPHPIQPATVLQTVPGVPPLGVSG 519

Query: 1063 GESFESPAALPAVPPEARTSFPLSESQTLLSSAPVPKVMLPSLAPSKFRKPYVRRRPSKR 1122
            GESFESPAALPA+PPEARTSFPLSESQTLLSSAPVPKVM+PS A S FRKPYVRRRPSKR
Sbjct: 520  GESFESPAALPAMPPEARTSFPLSESQTLLSSAPVPKVMMPSPASSMFRKPYVRRRPSKR 579

Query: 1123 RGVKASPCMKPAPVIHHPASVIFTVPATTVKIVSLGGGCNMIQPVNAAVAQSPQTIPITT 1182
            RG +A  C+KPAPVI HPASVIFTVPATTVKIVSLGGGCNMIQPVNAAVAQSPQTIPI T
Sbjct: 580  RGARAFRCIKPAPVI-HPASVIFTVPATTVKIVSLGGGCNMIQPVNAAVAQSPQTIPIAT 638

Query: 1183 LLVNPTSFPCPLNQSLVASSVSPLIVSGNSVNLPIPSTPEDKAHVNVDIACAVADGENAF 1242
            LLVNPTSFPCPLNQ LVASSVSPLIVSGNSVNLPIPSTPEDKAH+NVDIACAVADGENAF
Sbjct: 639  LLVNPTSFPCPLNQPLVASSVSPLIVSGNSVNLPIPSTPEDKAHMNVDIACAVADGENAF 698

Query: 1243 QGLEPKLEPQELSPLSATVFPKVEHSPGPPLADAECQEGLSENSACRWTVVKTEEGRQAL 1302
            QGLEPKLEPQELSPLSATVFPKVEHSPGPP  D +CQEGLSENSA RWTVVKTEEGRQAL
Sbjct: 699  QGLEPKLEPQELSPLSATVFPKVEHSPGPPPVDKQCQEGLSENSAYRWTVVKTEEGRQAL 758

Query: 1303 EPLPQGIQESLNNPTPGDLEEIVKMEPEEAREEISG 1338
            EPLPQGIQESLNN +PGDLEE+VKMEPE+A EEISG
Sbjct: 759  EPLPQGIQESLNNSSPGDLEEVVKMEPEDATEEISG 794


>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
          Length = 3230

 Score = 63.9 bits (154), Expect = 1e-09
 Identities = 74/294 (25%), Positives = 120/294 (40%), Gaps = 47/294 (15%)

Query: 1003 PLLIQPSPSLQPSFNPGKTPARSTHSEAPPS----KMVLRIPHPIQPATVLQTVPGVPPL 1058
            P ++ P P+L P   P  TP   T     P+    + +L++ H   P  V  + PG  PL
Sbjct: 1339 PAVLNPRPTLTPGRLP--TPTLGTARAPMPTPTLVRPLLKLVHSPSPE-VSASAPGAAPL 1395

Query: 1059 GVSGG----ESFESPAALPA-VPPEARTSFPLSESQTLLSSAPVPKVMLPSLAPSKFRKP 1113
             +S       S   PA+ P  +P  +  + P+S + ++  S+ +P + +P+  P+    P
Sbjct: 1396 TISSPLHVPSSLPGPASSPMPIPNSSPLASPVSSTVSVPLSSSLP-ISVPTTLPAPASAP 1454

Query: 1114 YVRRRPSKRRGVKASPCMKPAPVIHHPASVIFTVPATTVKIVSLGGGCNMIQPVNAAVAQ 1173
                           P   P  V     +++ +V      +V    G   + P  A+ + 
Sbjct: 1455 LT------------IPISAPLTVSASGPALLTSVTPPLAPVVPAAPGPPSLAPSGASPSA 1502

Query: 1174 SPQTIPITT-------------LLVNPTSFPCPLNQSLVASSVSPLIVSGNSVNLPIPST 1220
            S  T+ + T             LL+ PTS   P   S VA + SP++V  +++  P PS 
Sbjct: 1503 SALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAPACSPVLVPASALASPFPSA 1562

Query: 1221 PEDKAHVNVDIACAVADGENAFQGLEPKLEPQELSPLSATVFPKVEHSPGPPLA 1274
            P          A  +A   +A Q L   L P   +P +A + P    SP PPLA
Sbjct: 1563 PNPAPAQ----ASLLAPASSASQALATPLAPM-AAPQTAILAP----SPAPPLA 1607



 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 97/392 (24%), Positives = 146/392 (37%), Gaps = 93/392 (23%)

Query: 1085 LSESQTLLSSAPVPKVMLPSLAPSKFR--KPYVRRRPSKRRGVKASPCMKPAPVIHHPAS 1142
            +S  QT  ++ P      P  +P++ R  +P  R RP+      A P + P PV   P  
Sbjct: 2415 ISAHQTRSTTTP------PRCSPARERVPRPAPRPRPTPASAPAAIPALVPVPV-SAPVP 2467

Query: 1143 VIFTVPATTVKIVSLGGGCNMIQPVNAAVAQSPQTIPITTLLVNPTSFPCPLNQSLVASS 1202
            +    P T + +  L    +   P       SP   P       P   P P    LV  S
Sbjct: 2468 ISAPNPITILPVHILP---SPPPPSQIPPCSSPACTPPPACTPPPAHTPPPAQTCLVTPS 2524

Query: 1203 VSPLI-------VSGNSVNLPIPSTPEDK-------AHVNVDIACAVADGENAFQGLEPK 1248
             SPL+       +S +  NLP+   PE +       +  ++++A +VA  E +   L P 
Sbjct: 2525 -SPLLLGPPSVPISASVTNLPLGLRPEAELCAQALASPESLELA-SVASSETSSLSLVP- 2581

Query: 1249 LEPQELSPLSATVFPKVEHS----PGPPLADAEC------QEGLSENSACRWTVVKTEEG 1298
              P++L P++  + P  E +    P  P    E       QE  + +SA   T+    EG
Sbjct: 2582 --PKDLLPVAVEILPVSEKNLSLTPSAPSLTLEAGSIPNGQEQEAPDSAEGTTLTVLPEG 2639

Query: 1299 RQALEPLPQGIQESLNNPTPGDLEEIVKMEPEEAREEISGSPERDICDDIKVEHAVELDT 1358
                E LP  + ES            +++ P  A +E    P               L+ 
Sbjct: 2640 ----EELPLCVSESNG----------LELPPSAASDEPLQEP---------------LEA 2670

Query: 1359 GAPSEELSSAGEVTKQTVLQKEEERSQPTKTPSSSQEPPDEGTSGTDVNKGSSKNALSSM 1418
               SEEL+ A                   KTP+SS E P E  +       +S +A SS 
Sbjct: 2671 DRTSEELTEA-------------------KTPTSSPEKPQELVTAEVAAPSTSSSATSS- 2710

Query: 1419 DPEVRLSSPPGKPEDSSSVD--GQSVGTPVGP 1448
             PE    + P +   S+ V+  GQ  G P  P
Sbjct: 2711 -PEGPSPARPPRRRTSADVEIRGQGTGRPGQP 2741



 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 58/232 (25%), Positives = 90/232 (38%), Gaps = 22/232 (9%)

Query: 1008 PSPSLQPSFNPGKTPARSTHSEAPPSKMVLRIPHPIQPATVLQTVPGVPPLGVSGGESFE 1067
            P P + PS  PG + A ++   AP   +         P++    +P   P  +    S +
Sbjct: 1628 PVPVMAPSSTPGTSLASASPVPAPTPVLA--------PSSTQTMLPAPVPSPLPSPASTQ 1679

Query: 1068 SPAALPAVPPEARTSFPLSESQTLLSSAPVPKVMLP----SLAPSKFRKPYVRRRPSKRR 1123
            + A  PA+ P    S P   SQTL      P+   P    SL P+    P   +  S   
Sbjct: 1680 TLALAPALAPTLGGSSP---SQTLSLGTGNPQGPFPTQTLSLTPASSLVPTPAQTLSLAP 1736

Query: 1124 GVKASP----CMKPAPVIHHPASVIFTVPATTVKIVSLGGGCNMIQPVNA-AVAQSPQTI 1178
            G    P     + PAP +  PAS +   PA T+ +       +++ P +   +  SP  +
Sbjct: 1737 GPPLGPTQTLSLAPAPPL-APASPVGPAPAHTLTLAPASSSASLLAPASVQTLTLSPAPV 1795

Query: 1179 PITTLLVNPTSFPCPLNQSLVASSVSPLIVSGNSVNLPIPSTPEDKAHVNVD 1230
            P        T    P +    AS  S L+VS +    P+P T   +  V+ D
Sbjct: 1796 PTLGPAAAQTLALAPASTQSPASQASSLVVSASGA-APLPVTMVSRLPVSKD 1846



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 68/251 (27%), Positives = 104/251 (41%), Gaps = 55/251 (21%)

Query: 1237 DGENAFQGLEPKLEPQELSPLSATVFPKVEHSPGPPLADAECQEGLSENSACRWTVVKTE 1296
            +GE   + L   L PQ L   S+        S  P   D++ ++G  E +         E
Sbjct: 327  EGELPLEELLRSLPPQLLEGPSSP-------SQTPSSHDSDTRDGPEEGAE--------E 371

Query: 1297 EGRQALE--PLPQGIQESLNNP--TPGDLEEIVKMEPEEAREEISGSPERDICDDIKVEH 1352
            E  Q LE  P P  + +    P     D EE    E E   EE + + E  +  + +V+H
Sbjct: 372  EPPQVLEIKPPPSAVTQRNKQPWHPDEDDEEFTANEEEAEDEEDTIAAEEQL--EGEVDH 429

Query: 1353 AVELDTGAPSEELSSAGEVTKQTVLQKEEERSQPTKTPSSSQEPPDEGTSGTDVNKGSSK 1412
            A+EL       EL+  GE++ + +LQ+      P  + SS  E  DE     D N     
Sbjct: 430  AMELS------ELAREGELSMEELLQQYAGAYAPG-SGSSEDEDEDE----VDANS---- 474

Query: 1413 NALSSMDPEVRLSSPPGKPEDSSSVDGQSVGTPVGPETGGEKNGPEEEEEEDFDDLTQDE 1472
               S  +PE  + +     EDSSS                + +  E+  E++ D+ +++E
Sbjct: 475  ---SDCEPEGPVEAEEPPQEDSSS----------------QSDSVEDRSEDEEDEHSEEE 515

Query: 1473 EDEMSSASEES 1483
            E   SSASEES
Sbjct: 516  ETSGSSASEES 526



 Score = 35.4 bits (80), Expect = 0.43
 Identities = 31/106 (29%), Positives = 44/106 (41%), Gaps = 6/106 (5%)

Query: 1004 LLIQPSPSLQPSFNPGKTPARSTHSEAPPSKMVLRIPHPIQPATVLQTVPGVPPLGVSGG 1063
            L + P+P L P+   G  PA +       S   L  P  +Q  T L   P VP LG +  
Sbjct: 1746 LSLAPAPPLAPASPVGPAPAHTLTLAPASSSASLLAPASVQTLT-LSPAP-VPTLGPAAA 1803

Query: 1064 ESFESPAALPAVPPEARTSFPLSESQTLLSSAPVPKVMLPSLAPSK 1109
            ++     A    P    +S  +S S     +AP+P  M+  L  SK
Sbjct: 1804 QTLALAPASTQSPASQASSLVVSAS----GAAPLPVTMVSRLPVSK 1845



 Score = 35.0 bits (79), Expect = 0.56
 Identities = 76/380 (20%), Positives = 140/380 (36%), Gaps = 72/380 (18%)

Query: 137 RPGPVTQEDRCDHLTLKEPFSGEPSEEVKEEGGKPQMNSEGEIP------SLPSGS-QSA 189
           +P    +ED  + + ++E   G  +E  + E     +  EGE+P      SLP    +  
Sbjct: 290 QPQEDEEEDDEETIEVEEQQEGNDAEAQRRE--IELLRREGELPLEELLRSLPPQLLEGP 347

Query: 190 KPVSQPRKSTQPDVCASPQEKPLRTLFHQPEEEIEDGGLFIPMEEQDNEESEKRRKKKKG 249
              SQ   S   D    P+E        +P + +E       + +++ +        ++ 
Sbjct: 348 SSPSQTPSSHDSDTRDGPEEGAEE----EPPQVLEIKPPPSAVTQRNKQPWHPDEDDEEF 403

Query: 250 TKRKRDGRGQEGTLAYDLKLDDMLDRTLE--DGAKQHNLTAVNVRNILHEVITNEHVVAM 307
           T  + +   +E T+A + +L+  +D  +E  + A++  L+       + E++        
Sbjct: 404 TANEEEAEDEEDTIAAEEQLEGEVDHAMELSELAREGELS-------MEELLQQYAGAYA 456

Query: 308 MKAAISETEDMPMFEPKMTRSKLKEVVEKGVVIPTWNISPIKKANEIKPPQFVDIHLEED 367
             +  SE ED                 E  V   + +  P       +PPQ        +
Sbjct: 457 PGSGSSEDED-----------------EDEVDANSSDCEPEGPVEAEEPPQ--------E 491

Query: 368 DSSDEEYQPDDEEEDETAEESLLESDVESTASSPRGAKKSRLRQSSEMTETDEESG---- 423
           DSS +    +D  EDE  E S  E    S+AS    +++S   QS    + +EE      
Sbjct: 492 DSSSQSDSVEDRSEDEEDEHSEEEETSGSSASEESESEESEDAQSQSQADEEEEDDDFGV 551

Query: 424 --ILSEAEKVTTPAIRHISAEVVPMGPPPPPKPKQTRDSTFMEKLHAVDEELASSPVCMD 481
             +L+  E+          +E      PP P P     +T   K     +E+       +
Sbjct: 552 EYLLARDEE---------QSEADAGSGPPTPGP-----TTLGPK-----KEITDIAAAAE 592

Query: 482 SFQPMDDSLIAFRTRSKMPL 501
           S QP   +L   + ++ +PL
Sbjct: 593 SLQPKGYTLATTQVKTPIPL 612



 Score = 31.6 bits (70), Expect = 6.2
 Identities = 27/108 (25%), Positives = 41/108 (37%), Gaps = 2/108 (1%)

Query: 1347 DIKVEHAVELDTGAPSEELSSAGEVTKQTVLQKEEERSQPTKTPSSSQEPPDEGTSGTDV 1406
            D + E  VE +   P E+ SS  +  +     +E+E S+  +T  SS     E     D 
Sbjct: 476  DCEPEGPVEAEE-PPQEDSSSQSDSVEDRSEDEEDEHSEEEETSGSSASEESESEESEDA 534

Query: 1407 NKGSSKNALSSMDPEVRLSSPPGKPEDSSSVDGQSVGTPVGPETGGEK 1454
               S  +     D +  +     + E+ S  D  S     GP T G K
Sbjct: 535  QSQSQADE-EEEDDDFGVEYLLARDEEQSEADAGSGPPTPGPTTLGPK 581



 Score = 31.6 bits (70), Expect = 6.2
 Identities = 26/104 (25%), Positives = 47/104 (45%), Gaps = 13/104 (12%)

Query: 358  QFVDIHLEEDDSSDEEYQPDDEEEDETA------EESLLESDVESTASSPRGAKKSRLRQ 411
            +  D+ LEE  SS     P++EEE   +      E++L  ++ E    +   AK  ++ +
Sbjct: 2208 ELFDMPLEEPSSSSVPSAPEEEEETVASKQTHILEQALCRAEDEEDIRAATQAKAEQVAE 2267

Query: 412  SSEMTETD-------EESGILSEAEKVTTPAIRHISAEVVPMGP 448
             +E  E D       EE+G     ++  + A + I+A V  + P
Sbjct: 2268 LAEFNENDGFPAGEGEEAGRPGAEDEEMSRAEQEIAALVEQLTP 2311


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
          Length = 1124

 Score = 55.1 bits (131), Expect = 5e-07
 Identities = 60/224 (26%), Positives = 91/224 (40%), Gaps = 15/224 (6%)

Query: 981  LKPVATRFPRKAWRQKRSSVLKPLLIQPSPSLQPSFNPGKTPARSTHSEAPPSKMVLRIP 1040
            L P+AT  P+         +  P    PSP +Q  F+P  +P  S  S  PPS+    + 
Sbjct: 642  LSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSP-SATPPSQAPPSLA 700

Query: 1041 HPIQPATVLQTVPGVPPLGVSGGESFESPAALPA----VPPEARTSFPLSESQTLLSSAP 1096
             P  P  V  + P  PP+  S     ++P  L A    VPP    S P+S S T     P
Sbjct: 701  AP--PLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVP 758

Query: 1097 ----VPKVMLPSLAPSKFRKPYVRRRPSKRRGVKASPCMK--PAPVIHHPASVIFTVPAT 1150
                 P + +P   P+      + + P +     A+P ++  P+P    P    F+ P+ 
Sbjct: 759  PLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFS-PSA 817

Query: 1151 TVKIVSLGGGCNMIQPVNAA-VAQSPQTIPITTLLVNPTSFPCP 1193
            ++ +  L        PV AA + Q P + P +  L  P   P P
Sbjct: 818  SLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTP 861



 Score = 42.0 bits (97), Expect = 0.005
 Identities = 85/357 (23%), Positives = 126/357 (35%), Gaps = 62/357 (17%)

Query: 963  LGSESRYPLLLPKGVVLKLKPVA----TRFPRKAWRQKRSSVLKPL-LIQPSPSLQPSFN 1017
            LG  S  PL  P     K +PV        P  A       +  PL L  PSPS  PS  
Sbjct: 296  LGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQ 355

Query: 1018 PGKTPARSTHSEAPPSKMVLRIPHPIQPATVLQTVPGV---------------PPLGVSG 1062
               +P  +  S+APPS        P+Q    LQT+P +                PL +S 
Sbjct: 356  TLPSPPATPPSQAPPSMTT----PPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALS- 410

Query: 1063 GESFESPAALPAVPPEARTSF---PLSESQTLLSSAPVPKVMLPSLAPSKFRKPYVRRRP 1119
              S ++  +L +   +A  SF      ++Q  L+S   P    P   P +         P
Sbjct: 411  --SLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPP 468

Query: 1120 SKRRGVKASPCMKP--APVIHHPASVIFTV-------PATTVKIVSLGGGCNMIQPVNAA 1170
             +      SP + P  +P+  HP   + ++       P +++ +  L    ++  P    
Sbjct: 469  LQ---TSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQT 525

Query: 1171 VAQSPQTIPITTLLVNPTSFPCPLN-----------QSLVASSVSPLIVSGNSVNLPIPS 1219
               S  T P+  L   P+  P PL            ++    +  PL    + +  P P 
Sbjct: 526  PPASLTTPPLENL---PSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPE 582

Query: 1220 TPEDKAHVNVDIACAVADGENAFQGL-EPKLEPQELSPLSA---TVFPKVEHSPGPP 1272
            TP   A        A+A      QGL  P L P    P  A      P ++  P PP
Sbjct: 583  TPSSIATPPPQAPPALA--SPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPP 637



 Score = 40.8 bits (94), Expect = 0.010
 Identities = 56/247 (22%), Positives = 88/247 (35%), Gaps = 37/247 (14%)

Query: 995  QKRSSVLKPLLIQPSPSLQ------------PSFNPGKTPARSTHSEAPPSKMVLRIPHP 1042
            + +SS+  P L  P  SL             P       P  + H E PP       P P
Sbjct: 513  ETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPA----PCP 568

Query: 1043 IQPATVLQTVPGVPPLGVSGGESFESPAALPAVPPEARTSFPLSESQTLLSSAPVPKVML 1102
            +Q      T P  PP         E+P+++   PP+A  +      Q L S    P    
Sbjct: 569  LQAPPSPLTTP--PP---------ETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATP 617

Query: 1103 PSLAPSKFRKPYVRRRPSKRRGVKASPCMKPAP------VIHHPASVIFTVPATTVKIVS 1156
            P  AP     P ++  PS       SP   P+P       +H   +     P+  V+   
Sbjct: 618  PPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPF 677

Query: 1157 LGGGCNMIQPVNAAVAQSPQTIPITTLLV--NPTSFPCPLNQSLVASSVSPLIVSGNSVN 1214
                   + P     +Q+P ++    L V  +P + P P++ S      +P  ++   + 
Sbjct: 678  SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASP-PMSPSATPPPQAPPPLAAPPLQ 736

Query: 1215 LPIPSTP 1221
            +P PS P
Sbjct: 737  VP-PSPP 742


>gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]
          Length = 2089

 Score = 54.7 bits (130), Expect = 7e-07
 Identities = 100/445 (22%), Positives = 158/445 (35%), Gaps = 81/445 (18%)

Query: 994  RQKRSSVLKPLLIQPS-PSLQPSFNPGKTPARSTHSEAP-----------PSKMVLRIPH 1041
            R  RSSV  P  + P+ P LQPS +  +       S+A            P  +V   P 
Sbjct: 1436 RTNRSSVKTPETVVPTAPELQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPE 1495

Query: 1042 PIQPATVLQTVPGVPPLGVSGGESFESPA--------ALPAVPPEARTSFPLS------- 1086
                A+  Q V   P    + G    S          A P + P   T  P++       
Sbjct: 1496 LQASASTDQPVTSEPTSRTTRGRKNRSSVKTPETVVPAAPELQPSTSTDQPVTPEPTSRA 1555

Query: 1087 -ESQTLLSSAPVPKVMLP---SLAPSKFRKPYVRRRPSKRRG---VKASPCMKPAPVIH- 1138
               +T  SS   P+ ++P    L PS  R   V   P+ R        S    P PV+  
Sbjct: 1556 TRGRTNRSSVKTPESIVPIAPELQPSTSRNQLVTPEPTSRATRCRTNRSSVKTPEPVVPT 1615

Query: 1139 --HPASVIFTVPATTVKIVSLGGGCNMIQPVNAAVAQSPQTIPITTLLVNPTSFPCPLNQ 1196
               P     T    T K+ S        +  N +  ++P+ +      + P +   P +Q
Sbjct: 1616 APEPHPTTSTDQPVTPKLTSRATR----RKTNRSSVKTPKPVEPAASDLEPFT---PTDQ 1668

Query: 1197 SLVASSV-----SPLIVSGNSVNLPIPSTPEDKAHVNVDIACAVADGENAFQGLEPKLEP 1251
            S+   ++     S  + S     +P+P+TPE ++ V  D                  + P
Sbjct: 1669 SVTPEAIAQGGQSKTLRSSTVRAMPVPTTPEFQSPVTTD----------------QPISP 1712

Query: 1252 QELSPLSATVFPKVEHSPGP---PLADAECQEGLSENSAC----RWTVVKTEEGRQAL-E 1303
            + ++  S     +   +PG    P+    C   L   S      RW  V+  E   A+ E
Sbjct: 1713 EPITQPSCIKRQRAAGNPGSLAAPIDHKPCSAPLEPKSQASRNQRWGAVRAAESLTAIPE 1772

Query: 1304 PLPQGIQESLNNPTPGDLEEIVKMEPEEAREEISGSPERDICDDIKVEHAVELDTGAPSE 1363
            P    + E     TP    +I K+EP   R   +  PE         + ++      P +
Sbjct: 1773 PASPQLLE-----TPIHASQIQKVEPA-GRSRFT--PELQPKASQSRKRSLATMDSPPHQ 1824

Query: 1364 ELSSAGEVTKQTVLQKEEERSQPTK 1388
            +    GEV+++TV+ KEEE     K
Sbjct: 1825 KQPQRGEVSQKTVIIKEEEEDTAEK 1849


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 51.6 bits (122), Expect = 6e-06
 Identities = 127/622 (20%), Positives = 229/622 (36%), Gaps = 59/622 (9%)

Query: 91  ILEGVDVAISQG---ITLPS-LESFHPLNIHIG-KGKLHATGSKRGKKMTLRPGPVTQED 145
           +LEG +  I  G    +LP  L     ++ HI  K +      ++ +K T+     T+E 
Sbjct: 405 LLEGEECRIGFGPIPFSLPEGLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEET 464

Query: 146 RC-DHLTLKEPFSGEPSEEVKEEGGKPQMNSEGEIPSLPSGSQSAKPVSQPRKSTQPDVC 204
           +  + +T +E    +  E  +EEGG+ +    GE  +    ++ A    +  KS   +  
Sbjct: 465 QVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEA 524

Query: 205 ASPQE--KPLRTLFHQPEEEIEDGGLFIPMEEQDNEESEKRRKKK---------KGTKRK 253
            SP E   P +     P E         P +E+     E +  +K         K  ++ 
Sbjct: 525 KSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKA 584

Query: 254 RDGRGQEGTLAYDLKLDDMLDRTLEDGAKQHNLTAVNVRNILH---EVITNEHVVAMMK- 309
           +    +E     + K  +     +++ AK        V+       EV + E   +  K 
Sbjct: 585 KSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKE 644

Query: 310 -AAISETEDMPMFEPKMTRSKLKEVVEKGVVIPTWNISPIKKANEIKPPQFVDIHLEEDD 368
            A   E    P  E   +  K K  V+     P    SP+K   E K P+     ++E+ 
Sbjct: 645 EAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKA--EAKSPEKAKSPVKEEA 702

Query: 369 SSDEEYQPDDEEEDETAEESLLESDVESTASSPRGAKKSRLRQSSEMTETDEESGILSEA 428
            S E+ +   +EE ++ E++  +S V+  A +P  AK       S + E  +        
Sbjct: 703 KSPEKAKSPVKEEAKSPEKA--KSPVKEEAKTPEKAK-------SPVKEEAKSPEKAKSP 753

Query: 429 EKVTTPAIRHISAEVVPMGPPPPPKPKQTRDSTFMEKLHAVDEELASSPVCMDSFQPMDD 488
           EK  T  ++   A+         P  K    +    K      E A SP+  D+  P  +
Sbjct: 754 EKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAP--E 811

Query: 489 SLIAFRTRSKMPLKDVPLGQLEAELQAPDITPDMYDPNTADDEDWKMWLGGLMNDDVGNE 548
             I  +   K P+K+    Q     + P    +   P T   E+ K             +
Sbjct: 812 KEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKK----------DSKK 861

Query: 549 DEADDDDDPEYNFLEDLDEPDTEDFRTDRAVRITKKEVNELMEELFETFQDEMGFSNMED 608
           +EA   + P+   +E+  EP  E            K     +E   E  +D+      E 
Sbjct: 862 EEAPKKEAPKPK-VEEKKEPAVE------------KPKESKVEAKKEEAEDKKKVPTPEK 908

Query: 609 DGPEEEECVAEPRPNFNTPQALRFEEPLANLLNEQHRTVKELFEQLK-MKKSSAKQLQEV 667
           + P + E   + +P   T  A +  +        +    KE   + K  K+  AK+ +E 
Sbjct: 909 EAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEK 968

Query: 668 EKVKPQSEKVHQTLILDPAQRK 689
            K + ++++  +TL  +P++ K
Sbjct: 969 PKTEAKAKEDDKTLSKEPSKPK 990



 Score = 40.4 bits (93), Expect = 0.013
 Identities = 43/176 (24%), Positives = 78/176 (44%), Gaps = 12/176 (6%)

Query: 1325 VKMEPEEAREEIS-GSPERDICDDIKVEHAVELDTGAPS--EELSSAGEVTKQTVLQ-KE 1380
            VK  P++A EE +  +P+ +   D K E A + +   P   E+   A E  K++ ++ K+
Sbjct: 835  VKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKK 894

Query: 1381 EERSQPTKTPSSSQEPPDEGTSGTDVNKGSSKNALSSMDPEVRLSSPPGKPEDSSSVDGQ 1440
            EE     K P+  +E P +     D  K   K  ++  +P+   +  P KP +      +
Sbjct: 895  EEAEDKKKVPTPEKEAPAKVEVKEDA-KPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPE 953

Query: 1441 SVGT-PVGPETGGEKNGPEEEEEEDFDDLTQD------EEDEMSSASEESVLSVPE 1489
               T     +   EK   E + +ED   L+++      E+ E SS++++     PE
Sbjct: 954  KKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPE 1009



 Score = 39.3 bits (90), Expect = 0.030
 Identities = 94/458 (20%), Positives = 156/458 (34%), Gaps = 67/458 (14%)

Query: 1062 GGESFESPAALPAVPPEARTSFPLSESQTLLSSAPVPKVMLPSLAPSKFRKPYVRRRPSK 1121
            G E  +SP A  A  PE     P+ E     + A  P+    + +P++ + P   + P+K
Sbjct: 497  GEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPE-KEEAKSPAEVKSPEKAKSPAK 555

Query: 1122 RRGVKASPCMKPAPVIHHPASVIFTVPATTVKIVSLGGGCNMIQPVNAAVAQSPQTI--P 1179
                      K  P    P       PA  VK           +  + A A+SP+    P
Sbjct: 556  EEA-------KSPPEAKSPEKEEAKSPA-EVKSPEKAKSPAKEEAKSPAEAKSPEKAKSP 607

Query: 1180 ITTLLVNPTSFPCPLNQSLVASSVSPLIVSGNSVNLPIPSTPEDKAHVNVDIACAVADGE 1239
            +     +P     P+ +   + +         S       +PE       + A +    +
Sbjct: 608  VKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAK 667

Query: 1240 NAFQGLEPKLEPQELSPLSATV-------FPKVEHSPGPPLADAECQEGLSENSACRWTV 1292
            +  +  E K   +  SP+ A          P  E +  P  A +  +E        +  V
Sbjct: 668  SPVKA-EAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPV 726

Query: 1293 VKTEEGRQALEPLPQGIQESLNNPTPGDLEEIVKM-----------EPEEAREEISGSPE 1341
               +E  +  E     ++E   +P      E  K              EEAR      PE
Sbjct: 727  ---KEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPE 783

Query: 1342 R-------DICDDIKVEHAVELDTGAPSEELSSAGEVTKQTVLQKEEERSQPTKT---PS 1391
            +       ++    K +  ++ D  AP +E+    EV       KEEE+ Q  K    P 
Sbjct: 784  KAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPV---KEEEKPQEVKVKEPPK 840

Query: 1392 SSQEPPDEGTSGTDVNKGSSKNALSSMD---PEVRLSSPPG--KPEDS-------SSVDG 1439
             ++E     T  T+  K S K      +   P+V     P   KP++S        + D 
Sbjct: 841  KAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDK 900

Query: 1440 QSVGTPVGPETGGEKNGPEEEEEEDFDDLTQDEEDEMS 1477
            + V TP       EK  P + E +  +D    E+ E++
Sbjct: 901  KKVPTP-------EKEAPAKVEVK--EDAKPKEKTEVA 929



 Score = 37.4 bits (85), Expect = 0.11
 Identities = 37/169 (21%), Positives = 67/169 (39%), Gaps = 14/169 (8%)

Query: 1322 EEIVKMEPEEAREEISGSPERDICDDIKVEHAVELDTGAPSEELSSAGEVTKQTVLQKEE 1381
            EE+ + E +EA+EE     E +  ++ + E   E     P+EE +S  +  K  V   +E
Sbjct: 468  EEVTEEEEKEAKEE--EGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPV---KE 522

Query: 1382 ERSQPTKTPSSSQEP---------PDEGTSGTDVNKGSSKNALSSMDPEVRLSSPPGKPE 1432
            E   P +  S  +E          P++  S       S   A S    E +  +    PE
Sbjct: 523  EAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPE 582

Query: 1433 DSSSVDGQSVGTPVGPETGGEKNGPEEEEEEDFDDLTQDEEDEMSSASE 1481
             + S   +   +P   ++  +   P +EE +   +     ++E  S +E
Sbjct: 583  KAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAE 631



 Score = 32.0 bits (71), Expect = 4.7
 Identities = 29/128 (22%), Positives = 51/128 (39%), Gaps = 7/128 (5%)

Query: 1363 EELSSAGEVTKQTVLQKEE-ERSQPTKTPSSSQEPPDEGTSGTDVNKGSSKNALSSMDPE 1421
            E++    +  K+TV+ +E+ E +Q T+  +  +E   +   G +   G  + A      E
Sbjct: 442  EKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGG---E 498

Query: 1422 VRLSSPPGKPEDSSSVDGQSVGTPVGPETGGEKNGPEEEEEEDFDDLTQDEEDEMSSASE 1481
                SPP +   S   + +S   PV  E          E+EE          ++  S ++
Sbjct: 499  EETKSPPAEEAASPEKEAKS---PVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAK 555

Query: 1482 ESVLSVPE 1489
            E   S PE
Sbjct: 556  EEAKSPPE 563


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens]
          Length = 816

 Score = 51.2 bits (121), Expect = 8e-06
 Identities = 61/226 (26%), Positives = 90/226 (39%), Gaps = 32/226 (14%)

Query: 981  LKPVATRFPRKAWRQKRSSVLKPLLIQPSPSLQPSFNPGKTPARSTHSEAPPSKMVLRI- 1039
            L P+AT  P+       +  L PL   PSP   P  +P  TP     S   P+ + + + 
Sbjct: 347  LSPLATPPPQAP----PALALPPLQAPPSPPASPPLSPLATP-----SPQAPNALAVHLL 397

Query: 1040 -----PHPIQPATVLQTVPGVPPLGVSGGESFESPAALPA----VPPEARTSFPLSESQT 1090
                 P P  P     + P  PP+  S     ++P +L A    VPP    S P+S S T
Sbjct: 398  QAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSAT 457

Query: 1091 LLSSAPVPKVMLPSLAPSKFRKPYVRRRPSKRRGVKASPCMK--PAPVIHHPASVIFTVP 1148
                AP P     +  P +  KP     P +     A+P ++  P+P    P    F+ P
Sbjct: 458  PPPQAPPPL----AAPPLQLAKP-----PPQAPPALATPPLQALPSPPASFPGQAPFS-P 507

Query: 1149 ATTVKIVSLGGGCNMIQPVNAA-VAQSPQTIPITTLLVNPTSFPCP 1193
            + ++ +  L        PV AA + Q P + P +  L  P   P P
Sbjct: 508  SASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTP 553


>gi|4759128 solute carrier family 24 (sodium/potassium/calcium
            exchanger), member 1 [Homo sapiens]
          Length = 1099

 Score = 51.2 bits (121), Expect = 8e-06
 Identities = 46/190 (24%), Positives = 85/190 (44%), Gaps = 17/190 (8%)

Query: 1310 QESLNNPTPGDLEEIVKMEPEEAREE------ISGSPERDICDDIKVEHAVELDTGA--- 1360
            +ESLN       +   + +PEE          ++ +P  DI  D K     + D      
Sbjct: 693  EESLNQGARAQPQAKAESKPEEEEPAKLPAVTVTPAPVPDIKGDQKENPGGQEDVAEAES 752

Query: 1361 ----PSEELSSAGE--VTKQTVLQKEEERSQPTKTPSSSQEPPDEGTS-GTDVNKGSSKN 1413
                P EE  +AGE    +++  + + E    T+T    +E  DE  + G   N+G  + 
Sbjct: 753  TGEMPGEEGETAGEGETEEKSGGETQPEGEGETETQGKGEECEDENEAEGKGDNEGEDEG 812

Query: 1414 ALSSMDPEVRLSSPPGKPEDSSSVD-GQSVGTPVGPETGGEKNGPEEEEEEDFDDLTQDE 1472
             + + D E++ +    + ++ S+ + G++     G E GG  +G + EEEE+ ++  ++E
Sbjct: 813  EIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEE 872

Query: 1473 EDEMSSASEE 1482
            E+E     EE
Sbjct: 873  EEEEEQEEEE 882


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
            sapiens]
          Length = 5537

 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 169/768 (22%), Positives = 269/768 (35%), Gaps = 134/768 (17%)

Query: 820  PQDKIVFTKAEDNLLALGLKHFEGTEFPNPLISKYLLTCKTAHQLTVRIKNLNMNRAPDN 879
            P+D       ED+L++L            PL    LL      QL  R +  +++  P+ 
Sbjct: 702  PEDSPASPPPEDSLMSL------------PLEESPLLPLPEEPQLCPRSEGPHLSPRPEE 749

Query: 880  IIKFYKKTKQLPVLGKCCEEIQPHQWKPPIEREEHRLPFWLKASLPSIQEELRHMADGAR 939
                       P L    EE  PH    P   E H  P   +  L ++ EE  H++  A 
Sbjct: 750  -----------PHLSPRPEE--PHL--SPQAEEPHLSPQPEEPCLCAVPEE-PHLSPQAE 793

Query: 940  EVGNMTGTTEINSDRSLEKDNLELGSESRYPLLLPKGVVLKLKPVATR---FPRKAWRQK 996
                     E++     E+ +L    E   P L P+     L P +      PR      
Sbjct: 794  GPHLSPQPEELHLSPQTEEPHLSPVPEE--PCLSPQPEESHLSPQSEEPCLSPRPEESHL 851

Query: 997  RSSVLKPLLIQPSPSLQPSFNPGKTPARSTHSEAPPSKMVLRIPHPIQPATVLQTVPGVP 1056
               + KP L  P P   P   PG+ PA       PP       P   +PA    + PG P
Sbjct: 852  SPELEKPPL-SPRPEKPPE-EPGQCPAPEELPLFPPPGEPSLSPLLGEPAL---SEPGEP 906

Query: 1057 PLGVSGGESFESPAALPAVPPEARTSFPLSESQTLLSSAPVPKVMLPSLAP-SKFRKPYV 1115
            PL     E   SP+  P++ P+     PL    + + +A  P    P+L+P  +   P+ 
Sbjct: 907  PLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAP----PALSPLGELEYPFG 962

Query: 1116 RRRPSKRRGVKASP-------------CMKPAPV---IHHPASVIFTVPATTVKIVSLGG 1159
             +  S      A+P             C  P PV   I  P+      PA+ + +  L  
Sbjct: 963  AKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPP 1022

Query: 1160 GCN-----MIQPVNAAVAQ-SPQTIPITT---------------------LLVNPTSFP- 1191
             C+      + P N+  +Q SP  +P++                      +     S P 
Sbjct: 1023 QCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPE 1082

Query: 1192 CPLNQSLVASSVSPLIVSGNSVNLPIPSTP---EDKAHVNVDIACAV---ADGENAFQGL 1245
            CP   +L  S+ SPL      ++ P PS     +D + +  D A      A G     G 
Sbjct: 1083 CP---ALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQ 1139

Query: 1246 EPKLEPQELSPLSATVFPKVEHSPGPPL-ADAECQEGLSENSACRWTVVKTEEGRQALEP 1304
             P     EL      + P+ E +P  P+    EC++   + S C     + EE R  + P
Sbjct: 1140 TPGSLASELKGSPVLLDPE-ELAPVTPMEVYPECKQTAGQGSPCE----EQEEPRAPVAP 1194

Query: 1305 LPQGIQES-----LNNPTPGDLEEIVKMEPEEAREEISGSPERDICDDIKVEHAVELDTG 1359
             P  + +S     ++N + GD             E + GSP+ +    + +E  V  D  
Sbjct: 1195 TPPTLIKSDIVNEISNLSQGDASASFP-----GSEPLLGSPDPEGGGSLSMELGVSTDVS 1249

Query: 1360 APSEELSSAGEVTKQTVLQKEEERSQPTKTPSSSQEPPDEGTSG--------TDVNKGSS 1411
               +E    G +   T    E + S      ++      EG  G        + + +G S
Sbjct: 1250 PARDE----GSLRLCTDSLPETDDSLLCDAGTAISGGKAEGEKGRRRSSPARSRIKQGRS 1305

Query: 1412 KNALSSMDPEVRLSSPPGKPEDSSSVDGQSVGTPVGPETGGEKNGPEEEEEEDFDDLTQD 1471
             +      P        G+          S+ T V  +     + P +EEEE+ DD  Q+
Sbjct: 1306 SSFPGRRRPRGGAHGGRGRGRARLKSTASSIETLVVADID---SSPSKEEEEEDDDTMQN 1362

Query: 1472 EEDEMSSASEESVLSVPELQVRAGEYSQVFRGLSNMYHLLICHLLACC 1519
                 S+   +  + + ++ V  G + +   G     HLL C   + C
Sbjct: 1363 TVVLFSNT--DKFVLMQDMCVVCGSFGRGAEG-----HLLACSQCSQC 1403



 Score = 34.3 bits (77), Expect = 0.95
 Identities = 93/452 (20%), Positives = 154/452 (34%), Gaps = 66/452 (14%)

Query: 1057 PLGVSGGE---SFESPA--ALPAVPPEARTSFPLSESQTLLSSAPVPKVMLPSLAPSKFR 1111
            PLG +G +     E+P    +P +PP   +  PLS       ++P P+    S  P +  
Sbjct: 418  PLGKAGVQLEPQLEAPLNEEMPLLPPPEES--PLSPPPEESPTSPPPEASRLSPPPEELP 475

Query: 1112 KPYVRRRPSKRRGVKASPCMKP---APVIHHPASVIFTVPATTVKIVSLGGGCNMIQPVN 1168
               +       R ++ SP   P   +P+   P S  F+                   P+ 
Sbjct: 476  ASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFS-------------------PLE 516

Query: 1169 AAVAQSPQTIPITTLLVNPTSFP---CPLNQSLVASSVSPLIVSGNSVNLPIPSTPEDKA 1225
             +    P+  P +  L  P S P    PL+     S +SP           +P++P  +A
Sbjct: 517  ESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEE-------LPTSPPPEA 569

Query: 1226 HVNVDIACAVADGENAFQGLEPKLEPQELSPLSATVFPKVEHSPGPPLADAECQEGLSEN 1285
                  +      E +     P+  P    P ++ +FP  E SP  P  +   +  LS  
Sbjct: 570  ------SRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPE---ESPLSPP 620

Query: 1286 SACRWTVVKTEEGRQALEPLPQGIQESLNNPTP-----GDLEEIVKMEPEEAREEISGSP 1340
                      E+      P+    +ES  +P P       L  + ++ P      +S  P
Sbjct: 621  PEASRLSPPPED-----SPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPP 675

Query: 1341 ERDIC----DDIKVEHAVELDTGAPSEELSSAGEVTKQTVLQKEEERSQPTKTPSSSQEP 1396
            E        +  ++    E    +P  E S A    + +++    E S     P   Q  
Sbjct: 676  EESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLC 735

Query: 1397 PDEGTSGTDVNKGSSKNALSSMDPEVRLSSPPGKPEDSSSVDGQSV-GTPVGPETGGEKN 1455
            P   + G  ++    +  LS    E  LS    +P  S   +   +   P  P    +  
Sbjct: 736  P--RSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAE 793

Query: 1456 GPE-EEEEEDFDDLTQDEEDEMSSASEESVLS 1486
            GP    + E+     Q EE  +S   EE  LS
Sbjct: 794  GPHLSPQPEELHLSPQTEEPHLSPVPEEPCLS 825



 Score = 31.2 bits (69), Expect = 8.0
 Identities = 21/91 (23%), Positives = 46/91 (50%)

Query: 628  QALRFEEPLANLLNEQHRTVKELFEQLKMKKSSAKQLQEVEKVKPQSEKVHQTLILDPAQ 687
            Q L+ ++ L      Q +  ++L +Q ++++   +Q Q+ ++++ Q ++  Q       Q
Sbjct: 3898 QQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQ 3957

Query: 688  RKRLQQQMQQHVQLLTQIHLLATCNPNLNPE 718
            +++ QQQ  Q  Q   Q+ LL      L+P+
Sbjct: 3958 QQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQ 3988


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 140/604 (23%), Positives = 212/604 (35%), Gaps = 141/604 (23%)

Query: 967  SRYPLLLPKGVVLKLKPVATRFPRKAWRQKRSSVLKPLLIQPSPSLQPSFNPGKTPARST 1026
            SR   + P   +L  K  AT  P++A       ++ P +  PSP         KTPA  T
Sbjct: 1522 SRRDPIAPTATLLSKKTPATLAPKEA-------LIPPAMTVPSPK--------KTPAIPT 1566

Query: 1027 HSEAPPSKMVLRIPHPIQPATVLQTVPGVPPLGVSGGESFESPAALPAVPPEARTSFPLS 1086
              EAP +        P  PA    T  G P           SP  L  +PP   +  P  
Sbjct: 1567 PKEAPATPSSKEASSP--PAVTPSTYKGAP-----------SPKEL-LIPPAVTSPSP-- 1610

Query: 1087 ESQTLLSSAPVPKVMLPSLAPSKFRKPYVRRRPSKRRGVKASPCMKPAPVIHHPASVIF- 1145
                    AP P  + P   PS  + P         +G   SP + P+ +   P S    
Sbjct: 1611 ------KEAPTPPAVTP---PSPEKGPAT----PAPKGTPTSPPVTPSSLKDSPTSPASV 1657

Query: 1146 ------TVPATTVKIVSLGGGCNMIQPVNAAVAQSPQTIPITTLLV---------NPTSF 1190
                  TVP  +  + +  G   + + +   VA +P++ PI T            + TS 
Sbjct: 1658 TCKMGATVPQASKGLPAKKGPTALKEVL---VAPAPESTPIITAPTRKGPQTKKSSATSP 1714

Query: 1191 PCPLNQSLVASSVSPLIVSGNSVNLPIPSTPEDKAHVNVDIACAVADGENAFQGLEPKLE 1250
            P   + S    S  PL     S   P P  P  K       +   A G++A    +  L 
Sbjct: 1715 PICPDPSAKNGSKGPL-----STVAPAPLLPVQKD------SSKTAKGKDASHSPKGPLA 1763

Query: 1251 PQEL---SPLSATVFPKVEHSPGPPLADAECQEGLSENSACRWTVVKTEEGRQALEPLPQ 1307
            P E    +PL+A  F KV   P P  A          +     + V T   +Q   P   
Sbjct: 1764 PPESKASTPLTAAAFEKV--LPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSP 1821

Query: 1308 G-IQESLNNP-TPGDLEEIVKMEPEE-----------------------------AREEI 1336
            G + ES + P  P D +E++ + P E                             A++ +
Sbjct: 1822 GLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPV 1881

Query: 1337 S----GSPERDICDDIKVEHAVELDTGAPSEE--LSSAGEVTKQTVLQKEEERSQPTKTP 1390
            +    GS      D+   E   +  T A +++  L++A E+ ++ V + ++ RS+     
Sbjct: 1882 TKNNKGSGTESDSDESVPELEEQDSTQATTQQAQLAAAAEIDEEPVSKAKQSRSEKKARK 1941

Query: 1391 SSSQEPPDEGTSGTDVNKGSSKNALSSMDPEVRLSSP---------PGKPEDSS------ 1435
            + S+    + T  T V    SKN L  +       SP           K ED S      
Sbjct: 1942 AMSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPASDTYIVFGEAKIEDLSQQAQLA 2001

Query: 1436 -----SVDGQSVGTPVGPETGGEKNGPEEEEEEDFDDL---TQDEEDEMSSASEESVLSV 1487
                  V G++V      E        EE EEE+ D+     +D E  MS A+     +V
Sbjct: 2002 AAEKFKVQGEAVSNI--QENTQTPTVQEESEEEEVDETGVEVKDIELVMSQANVSRAKAV 2059

Query: 1488 PELQ 1491
              L+
Sbjct: 2060 RALK 2063



 Score = 40.0 bits (92), Expect = 0.017
 Identities = 110/493 (22%), Positives = 163/493 (33%), Gaps = 86/493 (17%)

Query: 1008 PSPSLQPSFNPGKTPARSTHSEAPPSKMVLRIPHP----IQPATVLQTVPGVPPLGVSGG 1063
            PS    P+         ST +  P  + V+  P P    + PATV    P V P    G 
Sbjct: 328  PSALSDPTVKTISVDHSSTGASYPSQRSVIP-PLPSRNEVVPATVA-AFPVVAPSVDKGP 385

Query: 1064 ESFESPAALPAVPPEARTSFPLSESQTLLSSAPVPKVMLPSLAPSKFRKPYVRRRPSKRR 1123
             +  S    P+      TSF LS         P   ++L S   + +  P V + P    
Sbjct: 386  STISSITCSPSGSLNVATSFSLS---------PTTSLILKSSPNATYHYPLVAQMPVSSV 436

Query: 1124 GVKASPCMKPAPVIHHPASVIFTVPATTVKIVSLGGGCNMIQP------VNAAVAQSPQT 1177
            G        P  +   P +  F V AT V      G  + I+P      V A VA    +
Sbjct: 437  GTTPLVVTNPCTIAAAPTTT-FEV-ATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPS 494

Query: 1178 IPITTLLVNPTSFPCPLNQSLVASSVSPLIVSGNSVNLPIPSTPEDKAHVNVDIACAVAD 1237
              + T L  P S P P  + L     S L+             P  K    V  +   A 
Sbjct: 495  TQVATTLRIPVSPPLPDPEDLKNLPSSVLV-----------KFPTQKDLQTVPASLEGAP 543

Query: 1238 GENAFQGLEPKLEPQEL-----SPLSATVFPKVEHSPGPPLAD----------------- 1275
               A  GL  K +P  L     +P ++  F     SP  PL+                  
Sbjct: 544  FSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGK 603

Query: 1276 --AECQEGLSENSACRWTVVKTEE--GRQALEPLPQGIQESLNNPT----PGDLEEIVKM 1327
              +     L  NS+   +V+KT+   G  +  PL   ++ SL  PT    P +  +   +
Sbjct: 604  PASSMTSPLGVNSSA--SVIKTDSYAGPDSAGPL---LKSSLITPTVAAFPLESADPAGV 658

Query: 1328 EPEEAREEISGSPERDICDDIKVEHAVELDTGAPSEELSSAGEVTKQTVLQKEEERSQPT 1387
             P  A+    G+          +E  V L   AP       G +T   ++    E     
Sbjct: 659  APTTAK----GTSTYTTTASPFLEGTVSL---APKNHPVKEGTLTTLPLVPTASENCPVA 711

Query: 1388 KTPSSSQEPPDEGTSGTDVNKGSSKNALSSMDPEVRLSSPPGKPEDSSSVDGQSVGTPVG 1447
             +P ++  P        ++ K     +L           P G P  +  VDG S  + + 
Sbjct: 712  PSPQNTCAPLATLVLAPEIPKSVPSPSLP----------PAGTPPGTKKVDGISHTSALA 761

Query: 1448 PETGGEKNGPEEE 1460
            P     K  P E+
Sbjct: 762  PVASSPKECPTED 774



 Score = 39.3 bits (90), Expect = 0.030
 Identities = 98/470 (20%), Positives = 142/470 (30%), Gaps = 37/470 (7%)

Query: 998  SSVLKPLLIQPSPSLQPSFNPGKTPARSTHSEAPPSKMVLRIPH---PIQPATVLQTVPG 1054
            SS + P+     P    SF   K    +THS  PPS      P    P+ P  V      
Sbjct: 825  SSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKE 884

Query: 1055 VPPLGVSGGESFESPAALPAVPPEARTSFPLSESQTLLSSAPVPKVMLPSLAPSKFRKPY 1114
             P   V      +   A PA P +A      S S     + P PK +  S +P     P 
Sbjct: 885  TPTPSVVNLPFPKEGPATPA-PKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPP 943

Query: 1115 VRRRPSKRRG-VKASPCMKPAPVIHHPASVIFTVPATTVKIVSLGGGCNMIQPVNAAVAQ 1173
                PS + G    SP   P P    P S        + K            P       
Sbjct: 944  AATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATP 1003

Query: 1174 SPQTIPITTLLVNPTSFPCPLNQSLVASSVSPLIVSGNSVNLPIPSTPEDKAHVNVDIAC 1233
            SP+  P    +  P+    P        + +P   +  S      +TP  K       A 
Sbjct: 1004 SPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAAT 1063

Query: 1234 AVA-DGENAFQGLEPKLEPQEL---SPLSATVFPKVEHSPGPPLADAECQEGLSENSACR 1289
              +  G  A   L+    P      SP      P  + +P PP A     +G       +
Sbjct: 1064 LPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHK 1123

Query: 1290 WTVVKTEEGRQALEPLPQGIQESLNNPTPGDLEEIVKMEPEEAREEISGSPERDICDDIK 1349
                       A  P P+G    L  P P          P   +  ++  P +       
Sbjct: 1124 GAPTTP----AATPPSPKG---GLATPPPKGAPTTPAATPPSPKGGLATPPPK------- 1169

Query: 1350 VEHAVELDTGAPSEELSSAGEVTKQTVLQKEEERSQPTKTPSSSQEPPDEGTSGTDVNKG 1409
                     GAP+    +A   + +  L     +  PT TP+++   P  G +       
Sbjct: 1170 ---------GAPT--TPAATPPSPKGGLATPSPKGAPT-TPAATPPSPKGGLATPSPKGA 1217

Query: 1410 SSKNALSSMDPEVRLS--SPPGKPEDSSSVDGQSVGTPVGPETGGEKNGP 1457
             +  A +   P+  L+  SP G P   ++      G P  P   G    P
Sbjct: 1218 PTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPP 1267



 Score = 37.7 bits (86), Expect = 0.086
 Identities = 113/536 (21%), Positives = 184/536 (34%), Gaps = 63/536 (11%)

Query: 982  KPVATRFPRKAWRQKRSSVLKPLLIQP-SPSLQPSFNPGKTPARSTHSEAPPSKMVLRIP 1040
            K  AT   R+         L P  + P S    P+ +  K    +  S+  P+   +  P
Sbjct: 1414 KAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPP 1473

Query: 1041 HPIQPATVLQTVPGVPPLGVSGGESFESPAALPAVPPEARTSFPLSESQTLLSSAP---- 1096
             P +P    Q      P       +      LPAV P +    P + S      AP    
Sbjct: 1474 SPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATL 1533

Query: 1097 VPKVMLPSLAPSKFRKPYVRRRPSKRRGVKASPCMKPAPVIHHPASVIFTVPATTVKIVS 1156
            + K    +LAP +   P     PS ++   A P  K AP    P+S   + P        
Sbjct: 1534 LSKKTPATLAPKEALIPPAMTVPSPKK-TPAIPTPKEAPAT--PSSKEASSPPAVTPSTY 1590

Query: 1157 LGGGCN---MIQPVNAAVAQSPQTIPITTLLVNPTSFPCPLNQSLVASSVSPLIVSGNSV 1213
             G       +I P  A  + SP+  P    +  P+    P   +   +  SP +      
Sbjct: 1591 KGAPSPKELLIPP--AVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVT----- 1643

Query: 1214 NLPIPSTPEDKAHVNVDIACAV-ADGENAFQGLEPKLEPQELSPLSATVFPKVEHSPGPP 1272
                PS+ +D       + C + A    A +GL  K  P  L  +     P+       P
Sbjct: 1644 ----PSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPE-----STP 1694

Query: 1273 LADAECQEG--LSENSACRWTVVKTEEGRQALEPLPQGIQESLNNPTPGDLEEIVKMEPE 1330
            +  A  ++G    ++SA    +      +        G +  L+   P  L  + K   +
Sbjct: 1695 IITAPTRKGPQTKKSSATSPPICPDPSAK-------NGSKGPLSTVAPAPLLPVQKDSSK 1747

Query: 1331 EAR-EEISGSPERDIC-DDIKVE---HAVELDTGAPSEELSSAGEVTKQTVLQKEEERSQ 1385
             A+ ++ S SP+  +   + K      A   +   P  E +S        V         
Sbjct: 1748 TAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPV 1807

Query: 1386 PTKTPSSSQEPPDEGTSGTDVNKGSSKNALSSMDPEVRLSSPP-----GKPEDSSSVD-- 1438
            PT  P     P   G     V +  SK    + + E+    PP     G P  S  V+  
Sbjct: 1808 PTLPPKQQFLPSSPGL----VLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMP 1863

Query: 1439 -GQSVGTPV------GPETGGEK-NGPEEEEEEDFDDLTQDEEDEMSSASEESVLS 1486
              +S G PV       P T   K +G E + +E   +L  +E+D   + ++++ L+
Sbjct: 1864 TPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPEL--EEQDSTQATTQQAQLA 1917



 Score = 36.6 bits (83), Expect = 0.19
 Identities = 58/219 (26%), Positives = 89/219 (40%), Gaps = 40/219 (18%)

Query: 1014 PSFNPGKTPARSTHSEAPPSKMVLRIPHPIQPATVLQTVPGVPPLGVSGGESFESPAALP 1073
            P  + G      T  EAP     L  P PI PA +    P + P  + G  S  +P AL 
Sbjct: 83   PQSSSGTALPLGTAPEAPTFLPNLIGP-PISPAALALASPMIAPT-LKGTPSSSAPLALV 140

Query: 1074 AVPPEA---RTSFPLSESQTLLSSAPVPKV--------MLPSLAPSKFRKPYVRRRPSKR 1122
            A+ P +    ++FP      LL+S P   V        +   +APS+  K  + + PS+ 
Sbjct: 141  ALAPHSVQKSSAFP----PNLLTSPPSVAVAESGSVITLSAPIAPSE-PKTNLNKVPSE- 194

Query: 1123 RGVKASPCMKPAPVIHHPASVIFTVPATTVKIVSLGGGCNMIQPVNAAVAQSPQTIPITT 1182
              V  +P   P+P       ++ TVP   V  ++          + + VA  PQT P TT
Sbjct: 195  --VVPNPKGTPSP-----PCIVSTVPYHCVTPMA---------SIQSGVASLPQTTPTTT 238

Query: 1183 LLVNPTSFPCPLNQSLVASSVSPLIVSGNSVNLPIPSTP 1221
            L +           S++ S  +P      S++L  P +P
Sbjct: 239  LAIASPQVKDTTISSVLISPQNP-----GSLSLKGPVSP 272



 Score = 35.8 bits (81), Expect = 0.33
 Identities = 92/404 (22%), Positives = 138/404 (34%), Gaps = 65/404 (16%)

Query: 939  REVGNMTGTTEINSDRSLEKDNLELGSESRYPLLLPKGVV-------LKLKPVATRFPRK 991
            +   +MT    +NS  S+ K +   G +S  PLL    +        L+    A   P  
Sbjct: 603  KPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTT 662

Query: 992  AWRQKRSSVLKPLLIQPSPSLQPSFNPGKTPARSTHSEAPPSKMVLRI-PHPIQPATVLQ 1050
            A      +      ++ + SL P  +P K    +T    P +     + P P      L 
Sbjct: 663  AKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLA 722

Query: 1051 TVPGVPPLGVSGGESFESPAALPA-VPPEARTSFPLSESQTLLSSAPVPKVM------LP 1103
            T+   P +     +S  SP+  PA  PP  +    +S +  L   A  PK          
Sbjct: 723  TLVLAPEI----PKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGAS 778

Query: 1104 SLAPSKFRKPYVRRRPSKRRGVKASPCMKPAPVIHHPASVIFTVPATTVKIVSLGGGCNM 1163
            + A SK    Y+   PS   GV  SP  K  P     A      P T   I +L    + 
Sbjct: 779  ATASSKGTLTYLADSPSP-LGVSVSPQTKRPPTKKGSAG-----PDT--PIGNLSSPVSP 830

Query: 1164 IQ----PVNAAVAQSPQTIPITTLLVNPTSFPCPLNQSLVASSVSPLIVSG--------- 1210
            ++    P N+   Q  +  P TT    P   P P   +   S+V+PL   G         
Sbjct: 831  VEASFLPENSLSFQGSKDSPATTHSPTP---PSP-KGAPTPSAVTPLSPKGVTLPPKETP 886

Query: 1211 --NSVNLPI----PSTPEDKAHVNVDIACAVADGENAFQGLEPKLEPQELSPLSATVFPK 1264
              + VNLP     P+TP  K    + +  +            PK      +P      P 
Sbjct: 887  TPSVVNLPFPKEGPATPAPKQAPALSMTSS-----------SPKKARATPAPKGIPASPS 935

Query: 1265 VEHSPGPPLADAECQEGLSENSACRWTVVKTEEGRQALEPLPQG 1308
             + +P PP A     +G     + +W          A  P P+G
Sbjct: 936  PKGAPTPPAATPPSPKGGPATPSPKWAPTPP----AATPPSPKG 975



 Score = 33.5 bits (75), Expect = 1.6
 Identities = 39/144 (27%), Positives = 56/144 (38%), Gaps = 7/144 (4%)

Query: 997  RSSVLKPLLIQPSPSLQPSFNPGKTPARSTHSEAPPS-KMVLRIPHPIQPATVLQTVPGV 1055
            + + + P    PSP    +  P K  A +T +  PPS K  L  P P    T     P  
Sbjct: 1100 KGAPMPPAATPPSPKGGLATPPHK-GAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPS 1158

Query: 1056 PPLGVSGGESFESPAALPAVPPEAR----TSFPLSESQTLLSSAPVPKVMLPSLAPSKFR 1111
            P  G++      +P    A PP  +    T  P     T  ++ P PK  L + +P    
Sbjct: 1159 PKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAP 1218

Query: 1112 KPYVRRRPSKRRGVKASPCMKPAP 1135
                   PS + G+ A+P  K AP
Sbjct: 1219 TTPAATPPSPKGGL-ATPSPKGAP 1241



 Score = 32.3 bits (72), Expect = 3.6
 Identities = 49/201 (24%), Positives = 76/201 (37%), Gaps = 23/201 (11%)

Query: 1008 PSPSLQPSFNPGKTPARSTHSEAPPSKMVLRIPHPIQPATVLQTVPGVPPLGVSGGES-F 1066
            P P  + +  P  +    T +   P      +P P  PA      P   PL  +   S F
Sbjct: 17   PQPQAETAVLPMSSALSVTAALGQPGPT---LPPPCSPA------PQQCPLSAANQASPF 67

Query: 1067 ESPAALPAVPPEARTSFPLSESQTL--LSSAPVPKVMLPSLAPSKFRKPYVRRRPSKRRG 1124
             SP+ + + P E    FP S S T   L +AP     LP+L       P +         
Sbjct: 68   PSPSTIASTPLE--VPFPQSSSGTALPLGTAPEAPTFLPNLI-----GPPISPAALALAS 120

Query: 1125 VKASPCMKPAPVIHHPASVIFTVPATTVKIVSLGGGCNMIQPVNAAVAQSPQTIPITTLL 1184
               +P +K  P    P +++   P +  K  +      +  P + AVA+S   I ++  +
Sbjct: 121  PMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNL-LTSPPSVAVAESGSVITLSAPI 179

Query: 1185 VNPTSFPCPLNQSLVASSVSP 1205
              P+     LN+  V S V P
Sbjct: 180  A-PSEPKTNLNK--VPSEVVP 197


>gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax
            homolog 2 [Homo sapiens]
          Length = 1210

 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 158/718 (22%), Positives = 245/718 (34%), Gaps = 158/718 (22%)

Query: 896  CCEEI---QPHQWKPPIER-------EEHRLPFWLKAS--LPSIQEELRHMADGAREVGN 943
            C EEI     H W PP+         E  + PF  K S  + S+ +  +     ++   N
Sbjct: 355  CVEEILKEMTHSWPPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSN 414

Query: 944  MTGTTEINSDRSLEKDNLELG-SESRYPLLLPKGVVLKLKPVATRFPRKAWRQKRSSVLK 1002
                T      S+ +D+L+L  SE       P+      KP ++  P  A      S+ +
Sbjct: 415  SQQGTS-----SMLEDDLQLSDSEDSDSEQTPE------KPPSSSAPPSA----PQSLPE 459

Query: 1003 PLLIQPSPSLQPSFNPGKTPARSTHSEAPPSK------MVLRIPHPIQPAT--------- 1047
            P+    S S +         +  + SE+  S       +    P P  P T         
Sbjct: 460  PVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWL 519

Query: 1048 VLQTVPGVPPLGVSGGESFESPAALPAVPPEARTSFPLSESQTLLSSAPVPKVMLPSLAP 1107
               + P  PP G    E        P   PE++ S   + SQ    S   P    P  + 
Sbjct: 520  TKVSQPAAPPEGPRSTEP-------PRRHPESKGSSDSATSQEHSESKDPP----PKSSS 568

Query: 1108 SKFRKPYVRRRPSKRRGVKASPCMKPAPVIHHPASVIFTVPATTVKIVSLGGGCNMIQPV 1167
               R P     P KR   K SP  +  P      +V    P   VK  +  G    +Q  
Sbjct: 569  KAPRAPPEAPHPGKRSCQK-SPAQQEPP---QRQTVGTKQPKKPVKASARAGSRTSLQG- 623

Query: 1168 NAAVAQSPQTIPITTLLVNPTSFPCPLNQSLVASSVSPLIVSGNSVNLPIPSTPEDKAHV 1227
                 + P  +P  +   + TS   P     V +   P   + N     +P + E K H 
Sbjct: 624  ----EREPGLLPYGSR--DQTSKDKPK----VKTKGRPRAAASNEPKPAVPPSSEKKKHK 673

Query: 1228 NVDIACAVADGENAFQGLEP-KLEPQELSPLSATVFPKVEHSPGPPLADAECQEGLSENS 1286
            +     ++     A  G EP K   ++ +P    + P  E S GPP + +      S  S
Sbjct: 674  S-----SLPAPSKALSGPEPAKDNVEDRTPEHFALVPLTE-SQGPPHSGSG-----SRTS 722

Query: 1287 ACRWTVVKTEEGRQALEPLPQGIQESLN--NPTPGDLEEIVKM----------------- 1327
             CR  VV  E+ R+   PLP    + L+    TP     +VK+                 
Sbjct: 723  GCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKGSR 782

Query: 1328 -------EPEEAREEIS----------------GSPERDICDDIKVEHAVEL----DTGA 1360
                   +P   ++  S                G  ERD CD+ K+    E+     + +
Sbjct: 783  QRKAEDKQPPAGKKHSSEKRSSDSSSKLAKKRKGEAERD-CDNKKIRLEKEIKSQSSSSS 841

Query: 1361 PSEELSSAGEVTKQTVLQKEEERSQPTKTPSSSQEPP---------DEGTSGTDVNKGSS 1411
             S + SS  + ++ +    ++E   P    SSSQ+P          +  T G D  K +S
Sbjct: 842  SSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPALKRSRREADTCGQDPPKSAS 901

Query: 1412 KNALSSMDPEV-RLSSPPGKPEDSSSVDGQSVGTPVGP------ETGGEKNG-PEEEEEE 1463
                +  D  + +     GK   SSS    S G    P        G  K G P+ + ++
Sbjct: 902  STKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTANPFPVPSLPNGNSKPGKPQVKFDK 961

Query: 1464 DFDDLTQDEEDEMSSASE-------------ESVLSVPELQVRAGEYSQVFRGLSNMY 1508
               DL   E  +M   +E             E+VLS  E  +     SQ  +   ++Y
Sbjct: 962  QQADLHMREAKKMKQKAELMTDRVGKAFKYLEAVLSFIECGIATESESQSSKSAYSVY 1019



 Score = 35.4 bits (80), Expect = 0.43
 Identities = 91/429 (21%), Positives = 151/429 (35%), Gaps = 61/429 (14%)

Query: 1025 STHSEAPPSKM--VLRIPHPIQPATVL----QTVPGVPPLGVSGGESFESPAALPAVPPE 1078
            S    AP  ++  ++ +P P+ P + +    QT+P         G S  S    PA  P+
Sbjct: 188  SVTDSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPK 247

Query: 1079 ARTSFPLSESQTLLSS--APV-------PKVMLPSLAPSKFRKP--YVRRRPSKRRGVKA 1127
               +  + + +T   S  AP        P   LPS + +  +KP  YVR    + +    
Sbjct: 248  D-LAVKVHDKETPQDSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSE 306

Query: 1128 SPCMKPAPVIHHPASVIFTVPATTVKIVSLGGGCNMIQPVNAA-VAQSPQTIPITTLLVN 1186
            SP +KP P  +       T   T +K+ +      +  P  +     S +   +  +L  
Sbjct: 307  SPELKPLPEDYRQQ----TFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVEEILKE 362

Query: 1187 PT-SFPCPLNQSLVASSVSPLIVSGNSVNLPIPSTPEDKAHVNVDIACAVADGENAFQGL 1245
             T S+P PL      S+  P          P P+  +D  HV+     +V   +  +   
Sbjct: 363  MTHSWPPPLTAIHTPSTAEP-------SKFPFPT--KDSQHVS-----SVTQNQKQYD-- 406

Query: 1246 EPKLEPQELSPLSATVFPKVEHSPGPPLADAECQEGLSENSACRWTVVKTEEGRQALEPL 1305
                        S+      +      L D + Q   SE+S    T  K      A    
Sbjct: 407  -----------TSSKTHSNSQQGTSSMLED-DLQLSDSEDSDSEQTPEKPPSS-SAPPSA 453

Query: 1306 PQGIQESLNNPTPGDLEEIVKMEPEEAREEISGSPERDICDDIKVEHAVELDTGAPSEEL 1365
            PQ + E + +      E     + + + +  S S   D       E    L+T AP  E 
Sbjct: 454  PQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSD------SEENEPLETPAPEPEP 507

Query: 1366 SSAGEVTKQTVLQKEEERSQPTKTPSSSQEPPDEGTSGTDVNKGSSKNALSSMDPEVRLS 1425
             +  +      L K  + + P + P S++ P     S    +  +S+    S DP  + S
Sbjct: 508  PTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATSQEHSESKDPPPKSS 567

Query: 1426 S--PPGKPE 1432
            S  P   PE
Sbjct: 568  SKAPRAPPE 576



 Score = 32.3 bits (72), Expect = 3.6
 Identities = 30/124 (24%), Positives = 50/124 (40%), Gaps = 13/124 (10%)

Query: 349 KKANEIKPPQFVDIHLEEDDSSDE-----EYQPDDEEEDETAEESLLESDVESTASSPRG 403
           +KA + +PP     H  E  SSD      + +  + E D   ++  LE +++S +SS   
Sbjct: 784 RKAEDKQPPAGKK-HSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIKSQSSSSSS 842

Query: 404 AKK-------SRLRQSSEMTETDEESGILSEAEKVTTPAIRHISAEVVPMGPPPPPKPKQ 456
           + K       SR    S   E      + S ++K   PA++    E    G  PP     
Sbjct: 843 SHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPALKRSRREADTCGQDPPKSASS 902

Query: 457 TRDS 460
           T+ +
Sbjct: 903 TKSN 906


>gi|221139926 NHS-like 1 [Homo sapiens]
          Length = 1606

 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 137/585 (23%), Positives = 208/585 (35%), Gaps = 92/585 (15%)

Query: 922  ASLPSIQEELRHMADGARE-VGNMTGTTEINSDRSLEKDNLELGSESRYP-------LLL 973
            + +P+    +RH+ +G+R  +  + G +      S EK +  +   S Y         L 
Sbjct: 804  SGVPTGNGPVRHVQEGSRATMPQVPGGSVKPKIMSPEKSHRVISPSSGYSSQSNTPTALT 863

Query: 974  PKGVVLKLKPVATRF--PRKAWRQKRSSVLKPLLIQPSP-------SLQPSFNPGKTPAR 1024
            P  V LK    A     P+    +++SS++  + I  S        S + S    K    
Sbjct: 864  PVPVFLKSVSPANGKGKPKPKVPERKSSLISSVSISSSSTSLSSSTSTEGSGTMKKLDPA 923

Query: 1025 STHSEAPPSKMVLRIPHPIQPATVLQTVPGVPPL-GVSGGESFESPAALPAVPPEARTSF 1083
                 APP   V   P P  PA     +P  PP+   S G         P  PPEA   F
Sbjct: 924  VGSPPAPPPPPVPSPPFPC-PADRSPFLPPPPPVTDCSQGSPLPHSPVFPPPPPEALIPF 982

Query: 1084 P------LSESQTLLS--------SAPVPKVMLPSLAPS-------KFRK----PYVRR- 1117
                   LS  +  LS        S P+P  +LPS  P        KF K    P+    
Sbjct: 983  CSPPDWCLSPPRPALSPILPDSPVSLPLPPPLLPSSEPPPAPPLDPKFMKDTRPPFTNSG 1042

Query: 1118 RPSKRRGVKASPCMKPAPVIHHPASVIFTVPATTVKI--VSLGGGCNMIQPVNAAVAQSP 1175
            +P   RG    P  K       P  +I T     V++  V    G    Q ++   AQ  
Sbjct: 1043 QPESSRGSLRPPSTKEE-TSRPPMPLITTEALQMVQLRPVRKNSGAEAAQ-LSERTAQEQ 1100

Query: 1176 QTIPITTLLVNPTSFPCPLNQSLVASSVS-PLIVSGNSVNLPIPSTPEDKAHVNVDIACA 1234
            +T       + P++F    N +    S S P  V+ +   LP P+    +          
Sbjct: 1101 RTPVAPQYHLKPSAFLKSRNSTNEMESESQPASVTSS---LPTPAKSSSQGD-------- 1149

Query: 1235 VADGENAFQGLEPKLEPQELSPLSATVFPKVEHSPGPPLADAECQEGLSENSACRWTVVK 1294
               G  A +G      P   S   A   P    +P P  + +     +S+     + VV 
Sbjct: 1150 --HGSAAERGGPVSRSPGAPSAGEAEARPSPSTTPLPDSSPSRKPPPISKKPKL-FLVVP 1206

Query: 1295 TEEGRQALEPLPQGIQESLN---NPTPGDLEEIVKMEPEEAREEISGSPERDICDDIKVE 1351
              +   A+EP  + + E+L    +PT G+   +   E +E+    +GS            
Sbjct: 1207 PPQKDFAVEPA-ENVSEALRAVPSPTTGEEGSVHSREAKESSAAQAGS------------ 1253

Query: 1352 HAVELDTGAPSEELSSAGEVTKQTVLQKEEERSQPTKTPSSSQEPPDEGTSGTDVNKGSS 1411
            HA     G    E  +AG ++   V +      QP  +P+  QE P E ++ T    G  
Sbjct: 1254 HATH--PGTSVLEGGAAGSMSPSRV-EANVPMVQPDVSPAPKQEEPAENSADTG---GDG 1307

Query: 1412 KNALSSMD-----PEVRLSSPPGKPEDSSSVDG-QSVGTPVGPET 1450
            ++ LS  D     PE   +    +  D    DG   V TP  P T
Sbjct: 1308 ESCLSQQDGAAGVPETNAAGSSSEACDFLKEDGNDEVMTPSRPRT 1352


>gi|117938310 sine oculis binding protein homolog [Homo sapiens]
          Length = 873

 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 108/526 (20%), Positives = 172/526 (32%), Gaps = 91/526 (17%)

Query: 1008 PSPSLQPSFNPGKTPARSTHSEAPPSK--MVLRIPHPIQPATVLQTVPGVPPLGVSGGES 1065
            PSP      + G  P+ ST      +    V +IP P+  +  +   P +PP+ V    S
Sbjct: 312  PSPVATAGQSQGPGPSASTTVSPSDTANCSVTKIPTPVPKSIPISETPNIPPVSVQPPAS 371

Query: 1066 FESPAALPAVPPEARTSFPLSESQTLLSSAPVP-KVMLPSLAPSKFRKPYVRRRP----- 1119
               P  +P          P S    + +  PVP  + +      + R P++R  P     
Sbjct: 372  IGPPLGVP----------PRSPPMVMTNRGPVPLPIFMEQQIMQQIRPPFIRGPPHHASN 421

Query: 1120 -------------------SKRRGVKASPCMKP--APVIHHPASVIF------------- 1145
                                +  G  +SP  +P  +P IH P++                
Sbjct: 422  PNSPLSNPMLPGIGPPPGGPRNLGPTSSPMHRPMLSPHIHPPSTPTMPGNPPGLLPPPPP 481

Query: 1146 --TVPATTVKIVSL--GGGCNMIQPVNAAVAQSPQTIPITTLLVN-------PTSFPCPL 1194
               +P+     VS+   G   + Q +N  +      +P  TLLV        P   P P+
Sbjct: 482  GAPLPSLPFPPVSMMPNGPMPVPQMMNFGLPSLAPLVPPPTLLVPYPVIVPLPVPIPIPI 541

Query: 1195 NQSLVASSVSPLIVSGNSVNLPIPSTPEDKAHVNVDIACAVADGENAFQGLEPKLEPQEL 1254
                V+ S  P   S N  N  IP+ P D          A A G+ +   L P+   Q  
Sbjct: 542  PIPHVSDSKPPNGFSSNGENF-IPNAPGDS---------AAAGGKPSGHSLSPRDSKQGS 591

Query: 1255 SPLSATVFPKVEHSPGPPLADAECQEGLSE-----NSACRWTVVKTEEGRQALEPLPQGI 1309
            S  + +  P         LA    + G SE       A          G+     + QG 
Sbjct: 592  SKSADS--PPGCSGQALSLAPTPAEHGRSEVVDLTRRAGSPPGPPGAGGQLGFPGVLQGP 649

Query: 1310 QESLNNPTPGD---LEEIV--KMEPEEAREEISGSPERDICDDIKVEHAVELDTGAPSEE 1364
            Q+ + + T G    L  ++   +      E    + ER  C   +  H      G P   
Sbjct: 650  QDGVIDLTVGHRARLHNVIHRALHAHVKAEREPSAAERRTCGGCRDGHCSPPAAGDPGPG 709

Query: 1365 LSSAGEVTKQTVLQKEEERSQPTKTPSSSQEPPDEGTSGTDVNKGSSKNALSSMDPEVR- 1423
              +  E      +     R    +   S++ PP++            K  LS  +P V  
Sbjct: 710  APAGPEAAAACNVIVNGTRGAAAEGAKSAEPPPEQPPPPPP--PAPPKKLLSPEEPAVSE 767

Query: 1424 -LSSPPGKPEDSSSVDGQSVGTPVGPE--TGGEKNGPEEEEEEDFD 1466
              S        +  +DG++    +G E   GG+K+ P      D D
Sbjct: 768  LESVKENNCASNCHLDGEAAKKLMGEEALAGGDKSDPNLNNPADED 813


>gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens]
          Length = 1711

 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 50/200 (25%), Positives = 72/200 (36%), Gaps = 25/200 (12%)

Query: 1018 PGKTPARSTHSEAPPSKMVLRIPHPIQPATVLQTV----PGVP-------PLGVSGGESF 1066
            P   PA   HS   P ++   +P P  P   +  +    P VP       PL VS     
Sbjct: 224  PLSVPAPVPHSGLVPVQVATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLV 283

Query: 1067 ESPAALP-------AVPPEARTSFPLSESQTLLSSAPVPKVMLPSLAPSKFRKPYVRRRP 1119
              PA+ P       + P  A  S P+S     L  APVP    P+L  +    P +   P
Sbjct: 284  PVPASAPPSGPVPLSAPAPAPLSVPVSAPPLALIQAPVPP-SAPTLVLAPVPTPVLAPMP 342

Query: 1120 SKRRGVKASPCMKPAPVIHHPASVIFTVPATTVKIVSLGGGCNMIQPVNAAV-AQSPQTI 1178
            +        P     P +  P     + P +T  ++       +  P  A +   +P  +
Sbjct: 343  A-----STPPAAPAPPSVPMPTPTPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPM 397

Query: 1179 PITTLLVNPTSFPCPLNQSL 1198
            P  T    PTS P P + SL
Sbjct: 398  PAATPAAIPTSAPIPASFSL 417



 Score = 33.5 bits (75), Expect = 1.6
 Identities = 62/227 (27%), Positives = 86/227 (37%), Gaps = 37/227 (16%)

Query: 1008 PSPSLQPSFNPGKTP-------ARSTHSEAPPSKMVLRIPHPIQPATVLQTVPGVPPLGV 1060
            P+P+  P F P  TP       A  T +  P S  + R+  P   A  +Q V    PL  
Sbjct: 382  PAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRVCFPAAQAPAMQKV----PLSF 437

Query: 1061 SGGESFESPAALPAVPPEARTSFPLSESQTLLSSAPVPKVMLPSLAPSKFRKPYVRRRPS 1120
              G        L  +PP +    PLS + TL ++  V   +   + PS     Y++ R  
Sbjct: 438  QPGTVLTPSQPLVYIPPPS-CGQPLSVA-TLPTTLGVSSTLTLPVLPS-----YLQDRCL 490

Query: 1121 KRRGVKASPCMKPAPVIHHPASVIFTVPATTVKIVSLGGGCNMIQPVNAAVAQSPQTIPI 1180
               GV ASP ++  P     A  +     +  K+VSL         VN     SP     
Sbjct: 491  P--GVLASPELRSYPYAFSVARPL----TSDSKLVSL--------EVNRLPCTSPS--GS 534

Query: 1181 TTLLVNPTSFPCPL-NQSLVASSVSPLIVSGNSVNLPIPSTPEDKAH 1226
            TT    P   P PL + SLV +S    ++      LP PS      H
Sbjct: 535  TTTQPAPDGVPGPLADTSLVTASAK--VLPTPQPLLPAPSGSSAPPH 579



 Score = 32.7 bits (73), Expect = 2.8
 Identities = 43/176 (24%), Positives = 72/176 (40%), Gaps = 15/176 (8%)

Query: 1045 PATVLQTVPGVPPLGVSGGESFESPAALPAVPPEARTSFPLSESQTLLSSAPVPKVMLPS 1104
            PA +    PG   +  S  ++F+ P ++PA  P +    P+  + ++ + +P P   +P+
Sbjct: 200  PAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGL-VPVQVATSVPAPSP-PLAPVPA 257

Query: 1105 LAPSKFRKPYVRRRPSKRRGVKASPCMKPAPVIHHPAS-VIFTVPATTVKIVSLGGGCNM 1163
            LAP+    P +    S    V AS  + P P    P+  V  + PA     V +      
Sbjct: 258  LAPAPPSVPTL-ISDSNPLSVSAS-VLVPVPASAPPSGPVPLSAPAPAPLSVPVSA---- 311

Query: 1164 IQPVNAAVAQSPQTIPITTLLVNPTSFPCPLNQSLVASSVSPLIVSGNSVNLPIPS 1219
              P+    A  P + P   L   PT    P+      +S  P   +  SV +P P+
Sbjct: 312  -PPLALIQAPVPPSAPTLVLAPVPTPVLAPM-----PASTPPAAPAPPSVPMPTPT 361


>gi|38788333 remodeling and spacing factor 1 [Homo sapiens]
          Length = 1441

 Score = 45.4 bits (106), Expect = 4e-04
 Identities = 86/374 (22%), Positives = 138/374 (36%), Gaps = 46/374 (12%)

Query: 129 KRGKKMTLRPGPVTQEDRCDHLTLKEPFSGEPSEEVKEEGGKPQM---------NSEGEI 179
           K  +KM     P+  E+R     L+E    +  E+ KE    P +         N E +I
Sbjct: 248 KESEKMKSEEQPMDLENRSTANVLEETTVKKEKEDEKELVKLPVIVKLEKPLPENEEKKI 307

Query: 180 PSLPSGS--QSAKPVSQPRKSTQPDV--CASPQEKPLRTLFHQPEEEIEDGGLFIPMEEQ 235
               S S  ++ KP+    K  + D     S  EKP+     Q  E IE GG      E 
Sbjct: 308 IKEESDSFKENVKPIKVEVKECRADPKDTKSSMEKPVA----QEPERIEFGGNIKSSHEI 363

Query: 236 DNEESEKRRKKKKGTKRKRDGRGQEGTLAYDL---------KLDDMLDRTLEDGAKQHNL 286
             + +E+  K K   + K   + +E  L+ D          K        L+D  KQ   
Sbjct: 364 TEKSTEETEKLKNDQQAKIPLKKREIKLSDDFDSPVKGPLCKSVTPTKEFLKDEIKQEEE 423

Query: 287 TAVNVRNIL---HE-------VITNEHVVAMMKAAISETEDMPMFEPKMTRSKLKEVVEK 336
           T   +  I    HE        +++E V    K    ET+     E   + SK + ++ +
Sbjct: 424 TCKRISTITALGHEGKQLVNGEVSDERVAPNFKTEPIETKFYETKEESYSPSKDRNIITE 483

Query: 337 GVVIPTWN-ISPIKKANEIKP---PQFVDIH-----LEEDDSSDEEYQPDDEEEDETAEE 387
           G    + N +    K  E++    P   D       LE      +  +PD  E + + + 
Sbjct: 484 GNGTESLNSVITSMKTGELEKETAPLRKDADSSISVLEIHSQKAQIEEPDPPEMETSLDS 543

Query: 388 SLLESDVES-TASSPRGAKKSRLRQSSEMTETDEESGILSEAEKVTTPAIRHISAEVVPM 446
           S +  D+ S TA S   +   +  + S  T+ D+   IL   EK+       +  +   +
Sbjct: 544 SEMAKDLSSKTALSSTESCTMKGEEKSPKTKKDKRPPILECLEKLEKSKKTFLDKDAQRL 603

Query: 447 GPPPPPKPKQTRDS 460
            P P   PK T +S
Sbjct: 604 SPIPEEVPKSTLES 617



 Score = 38.5 bits (88), Expect = 0.050
 Identities = 58/277 (20%), Positives = 105/277 (37%), Gaps = 39/277 (14%)

Query: 1201 SSVSPLIVSGNSVNLPIPSTPEDKAHVNVDIACAVADGENAFQGLEP-KLEPQELSPLSA 1259
            SS+S L +      +  P  PE +  ++          + A    E   ++ +E SP   
Sbjct: 515  SSISVLEIHSQKAQIEEPDPPEMETSLDSSEMAKDLSSKTALSSTESCTMKGEEKSP--- 571

Query: 1260 TVFPKVEHSPGPPLADAECQEGLSENSACRWTVVKTEEGRQALEPLPQGIQES-LNNPTP 1318
                K +    PP+   EC E L ++          ++  Q L P+P+ + +S L +  P
Sbjct: 572  ----KTKKDKRPPIL--ECLEKLEKSKK-----TFLDKDAQRLSPIPEEVPKSTLESEKP 620

Query: 1319 GDLEEIVKMEPE---EAREEISGSPERDICDDIKVEHAVELDTGAPSEELSSAGEVTKQT 1375
            G  E      P    +  E+++   E   C          +      E L    E TK  
Sbjct: 621  GSPEAAETSPPSNIIDHCEKLASEKEVVECQSTSTVGGQSVKK-VDLETLKEDSEFTKVE 679

Query: 1376 VLQKEEERS----QPTKTPSSSQEP-------PDEGTSGTDVNKGSSKNALSSMDPEVRL 1424
            +   +  ++    +P++T  S Q+        P+E T+ ++  + +S+     +   +R+
Sbjct: 680  MDNLDNAQTSGIEEPSETKGSMQKSKFKYKLVPEEETTASENTEITSERQKEGIKLTIRI 739

Query: 1425 SSPPGKPEDSSSVDGQSVGTPVGPETGGEKNGPEEEE 1461
            SS   KP+    V        + PE   EK   EEE+
Sbjct: 740  SSRKKKPDSPPKV--------LEPENKQEKTEKEEEK 768



 Score = 31.6 bits (70), Expect = 6.2
 Identities = 38/151 (25%), Positives = 53/151 (35%), Gaps = 24/151 (15%)

Query: 1328 EPEEAREEISGSPERDICDDIKVEHAVELDTGAPSEELSSAGEVTKQTVLQKEEERSQPT 1387
            E +E  EE  G P R     I+ +     D      + +     ++  VL  E+E    T
Sbjct: 1283 EADEEEEEEEGKPSRKRLHRIETDEEESCDNA--HGDANQPARDSQPRVLPSEQES---T 1337

Query: 1388 KTPSSSQEPPDEGTSGTDVNKGSSKNALSSMDPEVRLSSPPGK---------------PE 1432
            K P   +   DE     +V K  S    S +D        PGK               P+
Sbjct: 1338 KKPYRIES--DEEEDFENVGKVGSPLDYSLVDLPSTNGQSPGKAIENLIGKPTEKSQTPK 1395

Query: 1433 DSSSVDGQSVGTPVGPETGGEKNGPEEEEEE 1463
            D+S+          G   G E   PEEEE+E
Sbjct: 1396 DNSTASASLASN--GTSGGQEAGAPEEEEDE 1424


>gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 45.4 bits (106), Expect = 4e-04
 Identities = 67/278 (24%), Positives = 116/278 (41%), Gaps = 49/278 (17%)

Query: 333  VVEKGVVIPTWNISP-IKKANEIKPPQFVDIHLEEDDSSDEEYQPDDEEEDETAEESLLE 391
            V+E  V IP     P I+++ E   P+  D+ L E+   +EE Q + EE +E  EE    
Sbjct: 1188 VIEPIVSIPKAGRKPKIQESEETVEPK-EDMPLPEERKEEEEMQAEAEEAEEGEEEDAAS 1246

Query: 392  SDVESTASSPRGAKKSRLRQSSE-MTETDEESGILSEAEKVTTPAIRHISAEVVPMGPPP 450
            S+V   A+SP  +  S   ++ E   E +EE   +SE +       R    E   +  P 
Sbjct: 1247 SEV--PAASPADSSNSPETETKEPEVEEEEEKPRVSEEQ-------RQSEEEQQELEEPE 1297

Query: 451  PPKPKQTRDSTFMEKLHAVDE------------ELASSPVCMDSFQP---MDDSLIAFRT 495
            P + +     T     H  D+            EL   P   D  +     +  L A   
Sbjct: 1298 PEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQ 1357

Query: 496  RSKMPLKDVPLGQLEAELQAPDITPDMYDPNTADDEDWKMWLGGLMNDDVGNEDEADDDD 555
            +S+  +KD    +L++E + P      +D +   ++              G+ED+ ++D 
Sbjct: 1358 KSREKIKDKEETELDSEEEQPS-----HDTSVVSEQ------------MAGSEDDHEEDS 1400

Query: 556  DPEYNFLEDLDE---PDTE-DFRTDRAVR-ITKKEVNE 588
              +   +E  +E   P +E D  T +AV+ +T++E +E
Sbjct: 1401 HTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSE 1438



 Score = 35.0 bits (79), Expect = 0.56
 Identities = 38/190 (20%), Positives = 80/190 (42%), Gaps = 10/190 (5%)

Query: 1302 LEPLPQGIQESLNNPTPGDLEEIVKME-----PEEAREEISGSPERDICDDIKVEHAV-- 1354
            +EP+   I ++   P   + EE V+ +     PEE +EE     E +  ++ + E A   
Sbjct: 1189 IEPIVS-IPKAGRKPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASS 1247

Query: 1355 ELDTGAPSEELSSAGEVTKQTVLQKEEERSQPTKTPSSSQEPPDEGTSGTDVNKGSSKNA 1414
            E+   +P++  +S    TK+  +++EEE+ + ++    S+E   E        +  +   
Sbjct: 1248 EVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAE 1307

Query: 1415 LSSMDPEVRLSSPPGKPEDS--SSVDGQSVGTPVGPETGGEKNGPEEEEEEDFDDLTQDE 1472
             +  D         G  E +    ++ Q     V  E G +++  +   ++  + +   E
Sbjct: 1308 TAQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKE 1367

Query: 1473 EDEMSSASEE 1482
            E E+ S  E+
Sbjct: 1368 ETELDSEEEQ 1377



 Score = 34.7 bits (78), Expect = 0.73
 Identities = 55/287 (19%), Positives = 100/287 (34%), Gaps = 47/287 (16%)

Query: 153  KEPFSGEPSEEVKEEGGKPQMNSEGEIPSLPSGSQSAKPVSQPRKSTQPDVCASPQEKPL 212
            ++P   E  E V+ +   P      E   + + ++ A+   +   ++     ASP +   
Sbjct: 1200 RKPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSN 1259

Query: 213  RTLFHQPEEEIEDGGLFIPMEEQDNEESEKRRKKKKGTKRKRDGRGQEGTLAYDLKLDDM 272
                   E E+E+      + E+  +  E++++ ++    + +    E     D   DD 
Sbjct: 1260 SPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDE 1319

Query: 273  LDRTLEDGAKQHNLTAVNVRNILHEVITNEHVVAMMKAAISETEDMPMFEPKMTRSKLKE 332
             D  LE   K+                              E E+ P      TR  +KE
Sbjct: 1320 DDGHLESTKKK------------------------------ELEEQP------TREDVKE 1343

Query: 333  VVEKGVVIPTWNISPIKKANEIKPPQFVDIHLEEDDSSDEEY--------QPDDEEEDET 384
              E GV     + +  K   +IK  +  ++  EE+  S +            DD EED  
Sbjct: 1344 --EPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQMAGSEDDHEEDSH 1401

Query: 385  AEESLLE-SDVESTASSPRGAKKSRLRQSSEMTETDEESGILSEAEK 430
             +E L+E  + E    S    +  +  QS    E+ E  G   + E+
Sbjct: 1402 TKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEHEGAYQDCEE 1448



 Score = 33.5 bits (75), Expect = 1.6
 Identities = 75/344 (21%), Positives = 114/344 (33%), Gaps = 60/344 (17%)

Query: 924  LPSIQEELRHMAD-GAREVGNMTGTTEINSDRSLEKDNLELGS---------ESRYPLLL 973
            +PS+ +  + + D G  ++G++  TTE N +     D+   GS            Y  L 
Sbjct: 1535 VPSVSDHSQQVVDSGFSDLGSIESTTE-NYENPSSYDSTMGGSICGNSSSQSSCSYGGLS 1593

Query: 974  PKGVVLKLKPVATRFPRKAWRQKRSSVLKPLLIQPSPSLQPSFNPGKTPARSTHSEAPPS 1033
                + +   V T        Q+ +S+     +    S+QP+ N      +S   E PPS
Sbjct: 1594 SSSSLTQSSCVVT--------QQMASMGSSCSMMQQSSVQPAANCSIKSPQSCVVERPPS 1645

Query: 1034 KMVLRIP-----HPIQPATVLQTVPGVPPLGVSGGESFESPAALPAVPPEARTSFPLSES 1088
                + P      P  P    Q  P  PP      +  +     P  PP  +   PLS+ 
Sbjct: 1646 NQQQQPPPPPPQQPQPPPPQPQPAPQPPPPQQQPQQQPQPQPQQPPPPPPPQQQPPLSQC 1705

Query: 1089 QTLLSSAPVPKVM-LPSLAPSKFRKPYVRRRPSKRRGVKASP---------------CMK 1132
                S  P P +M +P    +     Y R       G  + P                M 
Sbjct: 1706 SMNNSFTPAPMIMEIPESGSTGNISIYERIPGDFGAGSYSQPSATFSLAKLQQLTNTIMD 1765

Query: 1133 P--APVIHHPASVIFTVPATTVKIVSLG---------------GGCNMIQPVNAAVAQSP 1175
            P   P  H PA    T  AT+V + + G                   M  P N A     
Sbjct: 1766 PHAMPYSHSPA---VTSYATSVSLSNTGLAQLAPSHPLAGTPQAQATMTPPPNLASTTMN 1822

Query: 1176 QTIPITTLLVNPTSFPCPLNQSLVASSVSPLIVSGNSVNLPIPS 1219
             T P+    ++ T+   P  Q L         +S  S + P+PS
Sbjct: 1823 LTSPLLQCNMSATNIGIPHTQRLQGQMPVKGHISIRSKSAPLPS 1866



 Score = 31.2 bits (69), Expect = 8.0
 Identities = 25/129 (19%), Positives = 54/129 (41%), Gaps = 15/129 (11%)

Query: 1363 EELSSAGEVTKQTVLQKEEERSQPTKT---PSSSQEPPDEGTSGTDVNKGSSKNALSSMD 1419
            E + S  +  ++  +Q+ EE  +P +    P   +E  +      +  +G  ++A SS  
Sbjct: 1190 EPIVSIPKAGRKPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASS-- 1247

Query: 1420 PEVRLSSPPGKPEDSSSVDGQSVGTPVGPETG-----GEKNGPEEEEEEDFDDLTQDEED 1474
                   P   P DSS+        P   E        E+    EEE+++ ++   +EE+
Sbjct: 1248 -----EVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEE 1302

Query: 1475 EMSSASEES 1483
            + ++ + ++
Sbjct: 1303 DAAAETAQN 1311


>gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 45.4 bits (106), Expect = 4e-04
 Identities = 67/278 (24%), Positives = 116/278 (41%), Gaps = 49/278 (17%)

Query: 333  VVEKGVVIPTWNISP-IKKANEIKPPQFVDIHLEEDDSSDEEYQPDDEEEDETAEESLLE 391
            V+E  V IP     P I+++ E   P+  D+ L E+   +EE Q + EE +E  EE    
Sbjct: 1188 VIEPIVSIPKAGRKPKIQESEETVEPK-EDMPLPEERKEEEEMQAEAEEAEEGEEEDAAS 1246

Query: 392  SDVESTASSPRGAKKSRLRQSSE-MTETDEESGILSEAEKVTTPAIRHISAEVVPMGPPP 450
            S+V   A+SP  +  S   ++ E   E +EE   +SE +       R    E   +  P 
Sbjct: 1247 SEV--PAASPADSSNSPETETKEPEVEEEEEKPRVSEEQ-------RQSEEEQQELEEPE 1297

Query: 451  PPKPKQTRDSTFMEKLHAVDE------------ELASSPVCMDSFQP---MDDSLIAFRT 495
            P + +     T     H  D+            EL   P   D  +     +  L A   
Sbjct: 1298 PEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQ 1357

Query: 496  RSKMPLKDVPLGQLEAELQAPDITPDMYDPNTADDEDWKMWLGGLMNDDVGNEDEADDDD 555
            +S+  +KD    +L++E + P      +D +   ++              G+ED+ ++D 
Sbjct: 1358 KSREKIKDKEETELDSEEEQPS-----HDTSVVSEQ------------MAGSEDDHEEDS 1400

Query: 556  DPEYNFLEDLDE---PDTE-DFRTDRAVR-ITKKEVNE 588
              +   +E  +E   P +E D  T +AV+ +T++E +E
Sbjct: 1401 HTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSE 1438



 Score = 35.0 bits (79), Expect = 0.56
 Identities = 38/190 (20%), Positives = 80/190 (42%), Gaps = 10/190 (5%)

Query: 1302 LEPLPQGIQESLNNPTPGDLEEIVKME-----PEEAREEISGSPERDICDDIKVEHAV-- 1354
            +EP+   I ++   P   + EE V+ +     PEE +EE     E +  ++ + E A   
Sbjct: 1189 IEPIVS-IPKAGRKPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASS 1247

Query: 1355 ELDTGAPSEELSSAGEVTKQTVLQKEEERSQPTKTPSSSQEPPDEGTSGTDVNKGSSKNA 1414
            E+   +P++  +S    TK+  +++EEE+ + ++    S+E   E        +  +   
Sbjct: 1248 EVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAE 1307

Query: 1415 LSSMDPEVRLSSPPGKPEDS--SSVDGQSVGTPVGPETGGEKNGPEEEEEEDFDDLTQDE 1472
             +  D         G  E +    ++ Q     V  E G +++  +   ++  + +   E
Sbjct: 1308 TAQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKE 1367

Query: 1473 EDEMSSASEE 1482
            E E+ S  E+
Sbjct: 1368 ETELDSEEEQ 1377



 Score = 34.7 bits (78), Expect = 0.73
 Identities = 55/287 (19%), Positives = 100/287 (34%), Gaps = 47/287 (16%)

Query: 153  KEPFSGEPSEEVKEEGGKPQMNSEGEIPSLPSGSQSAKPVSQPRKSTQPDVCASPQEKPL 212
            ++P   E  E V+ +   P      E   + + ++ A+   +   ++     ASP +   
Sbjct: 1200 RKPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSN 1259

Query: 213  RTLFHQPEEEIEDGGLFIPMEEQDNEESEKRRKKKKGTKRKRDGRGQEGTLAYDLKLDDM 272
                   E E+E+      + E+  +  E++++ ++    + +    E     D   DD 
Sbjct: 1260 SPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDE 1319

Query: 273  LDRTLEDGAKQHNLTAVNVRNILHEVITNEHVVAMMKAAISETEDMPMFEPKMTRSKLKE 332
             D  LE   K+                              E E+ P      TR  +KE
Sbjct: 1320 DDGHLESTKKK------------------------------ELEEQP------TREDVKE 1343

Query: 333  VVEKGVVIPTWNISPIKKANEIKPPQFVDIHLEEDDSSDEEY--------QPDDEEEDET 384
              E GV     + +  K   +IK  +  ++  EE+  S +            DD EED  
Sbjct: 1344 --EPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQMAGSEDDHEEDSH 1401

Query: 385  AEESLLE-SDVESTASSPRGAKKSRLRQSSEMTETDEESGILSEAEK 430
             +E L+E  + E    S    +  +  QS    E+ E  G   + E+
Sbjct: 1402 TKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEHEGAYQDCEE 1448



 Score = 33.5 bits (75), Expect = 1.6
 Identities = 75/344 (21%), Positives = 114/344 (33%), Gaps = 60/344 (17%)

Query: 924  LPSIQEELRHMAD-GAREVGNMTGTTEINSDRSLEKDNLELGS---------ESRYPLLL 973
            +PS+ +  + + D G  ++G++  TTE N +     D+   GS            Y  L 
Sbjct: 1535 VPSVSDHSQQVVDSGFSDLGSIESTTE-NYENPSSYDSTMGGSICGNSSSQSSCSYGGLS 1593

Query: 974  PKGVVLKLKPVATRFPRKAWRQKRSSVLKPLLIQPSPSLQPSFNPGKTPARSTHSEAPPS 1033
                + +   V T        Q+ +S+     +    S+QP+ N      +S   E PPS
Sbjct: 1594 SSSSLTQSSCVVT--------QQMASMGSSCSMMQQSSVQPAANCSIKSPQSCVVERPPS 1645

Query: 1034 KMVLRIP-----HPIQPATVLQTVPGVPPLGVSGGESFESPAALPAVPPEARTSFPLSES 1088
                + P      P  P    Q  P  PP      +  +     P  PP  +   PLS+ 
Sbjct: 1646 NQQQQPPPPPPQQPQPPPPQPQPAPQPPPPQQQPQQQPQPQPQQPPPPPPPQQQPPLSQC 1705

Query: 1089 QTLLSSAPVPKVM-LPSLAPSKFRKPYVRRRPSKRRGVKASP---------------CMK 1132
                S  P P +M +P    +     Y R       G  + P                M 
Sbjct: 1706 SMNNSFTPAPMIMEIPESGSTGNISIYERIPGDFGAGSYSQPSATFSLAKLQQLTNTIMD 1765

Query: 1133 P--APVIHHPASVIFTVPATTVKIVSLG---------------GGCNMIQPVNAAVAQSP 1175
            P   P  H PA    T  AT+V + + G                   M  P N A     
Sbjct: 1766 PHAMPYSHSPA---VTSYATSVSLSNTGLAQLAPSHPLAGTPQAQATMTPPPNLASTTMN 1822

Query: 1176 QTIPITTLLVNPTSFPCPLNQSLVASSVSPLIVSGNSVNLPIPS 1219
             T P+    ++ T+   P  Q L         +S  S + P+PS
Sbjct: 1823 LTSPLLQCNMSATNIGIPHTQRLQGQMPVKGHISIRSKSAPLPS 1866



 Score = 31.2 bits (69), Expect = 8.0
 Identities = 25/129 (19%), Positives = 54/129 (41%), Gaps = 15/129 (11%)

Query: 1363 EELSSAGEVTKQTVLQKEEERSQPTKT---PSSSQEPPDEGTSGTDVNKGSSKNALSSMD 1419
            E + S  +  ++  +Q+ EE  +P +    P   +E  +      +  +G  ++A SS  
Sbjct: 1190 EPIVSIPKAGRKPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASS-- 1247

Query: 1420 PEVRLSSPPGKPEDSSSVDGQSVGTPVGPETG-----GEKNGPEEEEEEDFDDLTQDEED 1474
                   P   P DSS+        P   E        E+    EEE+++ ++   +EE+
Sbjct: 1248 -----EVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEE 1302

Query: 1475 EMSSASEES 1483
            + ++ + ++
Sbjct: 1303 DAAAETAQN 1311


>gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 45.4 bits (106), Expect = 4e-04
 Identities = 67/278 (24%), Positives = 116/278 (41%), Gaps = 49/278 (17%)

Query: 333  VVEKGVVIPTWNISP-IKKANEIKPPQFVDIHLEEDDSSDEEYQPDDEEEDETAEESLLE 391
            V+E  V IP     P I+++ E   P+  D+ L E+   +EE Q + EE +E  EE    
Sbjct: 1188 VIEPIVSIPKAGRKPKIQESEETVEPK-EDMPLPEERKEEEEMQAEAEEAEEGEEEDAAS 1246

Query: 392  SDVESTASSPRGAKKSRLRQSSE-MTETDEESGILSEAEKVTTPAIRHISAEVVPMGPPP 450
            S+V   A+SP  +  S   ++ E   E +EE   +SE +       R    E   +  P 
Sbjct: 1247 SEV--PAASPADSSNSPETETKEPEVEEEEEKPRVSEEQ-------RQSEEEQQELEEPE 1297

Query: 451  PPKPKQTRDSTFMEKLHAVDE------------ELASSPVCMDSFQP---MDDSLIAFRT 495
            P + +     T     H  D+            EL   P   D  +     +  L A   
Sbjct: 1298 PEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQ 1357

Query: 496  RSKMPLKDVPLGQLEAELQAPDITPDMYDPNTADDEDWKMWLGGLMNDDVGNEDEADDDD 555
            +S+  +KD    +L++E + P      +D +   ++              G+ED+ ++D 
Sbjct: 1358 KSREKIKDKEETELDSEEEQPS-----HDTSVVSEQ------------MAGSEDDHEEDS 1400

Query: 556  DPEYNFLEDLDE---PDTE-DFRTDRAVR-ITKKEVNE 588
              +   +E  +E   P +E D  T +AV+ +T++E +E
Sbjct: 1401 HTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSE 1438



 Score = 35.0 bits (79), Expect = 0.56
 Identities = 38/190 (20%), Positives = 80/190 (42%), Gaps = 10/190 (5%)

Query: 1302 LEPLPQGIQESLNNPTPGDLEEIVKME-----PEEAREEISGSPERDICDDIKVEHAV-- 1354
            +EP+   I ++   P   + EE V+ +     PEE +EE     E +  ++ + E A   
Sbjct: 1189 IEPIVS-IPKAGRKPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASS 1247

Query: 1355 ELDTGAPSEELSSAGEVTKQTVLQKEEERSQPTKTPSSSQEPPDEGTSGTDVNKGSSKNA 1414
            E+   +P++  +S    TK+  +++EEE+ + ++    S+E   E        +  +   
Sbjct: 1248 EVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAE 1307

Query: 1415 LSSMDPEVRLSSPPGKPEDS--SSVDGQSVGTPVGPETGGEKNGPEEEEEEDFDDLTQDE 1472
             +  D         G  E +    ++ Q     V  E G +++  +   ++  + +   E
Sbjct: 1308 TAQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKE 1367

Query: 1473 EDEMSSASEE 1482
            E E+ S  E+
Sbjct: 1368 ETELDSEEEQ 1377



 Score = 34.7 bits (78), Expect = 0.73
 Identities = 55/287 (19%), Positives = 100/287 (34%), Gaps = 47/287 (16%)

Query: 153  KEPFSGEPSEEVKEEGGKPQMNSEGEIPSLPSGSQSAKPVSQPRKSTQPDVCASPQEKPL 212
            ++P   E  E V+ +   P      E   + + ++ A+   +   ++     ASP +   
Sbjct: 1200 RKPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSN 1259

Query: 213  RTLFHQPEEEIEDGGLFIPMEEQDNEESEKRRKKKKGTKRKRDGRGQEGTLAYDLKLDDM 272
                   E E+E+      + E+  +  E++++ ++    + +    E     D   DD 
Sbjct: 1260 SPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDE 1319

Query: 273  LDRTLEDGAKQHNLTAVNVRNILHEVITNEHVVAMMKAAISETEDMPMFEPKMTRSKLKE 332
             D  LE   K+                              E E+ P      TR  +KE
Sbjct: 1320 DDGHLESTKKK------------------------------ELEEQP------TREDVKE 1343

Query: 333  VVEKGVVIPTWNISPIKKANEIKPPQFVDIHLEEDDSSDEEY--------QPDDEEEDET 384
              E GV     + +  K   +IK  +  ++  EE+  S +            DD EED  
Sbjct: 1344 --EPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQMAGSEDDHEEDSH 1401

Query: 385  AEESLLE-SDVESTASSPRGAKKSRLRQSSEMTETDEESGILSEAEK 430
             +E L+E  + E    S    +  +  QS    E+ E  G   + E+
Sbjct: 1402 TKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEHEGAYQDCEE 1448



 Score = 33.5 bits (75), Expect = 1.6
 Identities = 75/344 (21%), Positives = 114/344 (33%), Gaps = 60/344 (17%)

Query: 924  LPSIQEELRHMAD-GAREVGNMTGTTEINSDRSLEKDNLELGS---------ESRYPLLL 973
            +PS+ +  + + D G  ++G++  TTE N +     D+   GS            Y  L 
Sbjct: 1535 VPSVSDHSQQVVDSGFSDLGSIESTTE-NYENPSSYDSTMGGSICGNSSSQSSCSYGGLS 1593

Query: 974  PKGVVLKLKPVATRFPRKAWRQKRSSVLKPLLIQPSPSLQPSFNPGKTPARSTHSEAPPS 1033
                + +   V T        Q+ +S+     +    S+QP+ N      +S   E PPS
Sbjct: 1594 SSSSLTQSSCVVT--------QQMASMGSSCSMMQQSSVQPAANCSIKSPQSCVVERPPS 1645

Query: 1034 KMVLRIP-----HPIQPATVLQTVPGVPPLGVSGGESFESPAALPAVPPEARTSFPLSES 1088
                + P      P  P    Q  P  PP      +  +     P  PP  +   PLS+ 
Sbjct: 1646 NQQQQPPPPPPQQPQPPPPQPQPAPQPPPPQQQPQQQPQPQPQQPPPPPPPQQQPPLSQC 1705

Query: 1089 QTLLSSAPVPKVM-LPSLAPSKFRKPYVRRRPSKRRGVKASP---------------CMK 1132
                S  P P +M +P    +     Y R       G  + P                M 
Sbjct: 1706 SMNNSFTPAPMIMEIPESGSTGNISIYERIPGDFGAGSYSQPSATFSLAKLQQLTNTIMD 1765

Query: 1133 P--APVIHHPASVIFTVPATTVKIVSLG---------------GGCNMIQPVNAAVAQSP 1175
            P   P  H PA    T  AT+V + + G                   M  P N A     
Sbjct: 1766 PHAMPYSHSPA---VTSYATSVSLSNTGLAQLAPSHPLAGTPQAQATMTPPPNLASTTMN 1822

Query: 1176 QTIPITTLLVNPTSFPCPLNQSLVASSVSPLIVSGNSVNLPIPS 1219
             T P+    ++ T+   P  Q L         +S  S + P+PS
Sbjct: 1823 LTSPLLQCNMSATNIGIPHTQRLQGQMPVKGHISIRSKSAPLPS 1866



 Score = 31.2 bits (69), Expect = 8.0
 Identities = 25/129 (19%), Positives = 54/129 (41%), Gaps = 15/129 (11%)

Query: 1363 EELSSAGEVTKQTVLQKEEERSQPTKT---PSSSQEPPDEGTSGTDVNKGSSKNALSSMD 1419
            E + S  +  ++  +Q+ EE  +P +    P   +E  +      +  +G  ++A SS  
Sbjct: 1190 EPIVSIPKAGRKPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASS-- 1247

Query: 1420 PEVRLSSPPGKPEDSSSVDGQSVGTPVGPETG-----GEKNGPEEEEEEDFDDLTQDEED 1474
                   P   P DSS+        P   E        E+    EEE+++ ++   +EE+
Sbjct: 1248 -----EVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEE 1302

Query: 1475 EMSSASEES 1483
            + ++ + ++
Sbjct: 1303 DAAAETAQN 1311


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 45.1 bits (105), Expect = 5e-04
 Identities = 79/306 (25%), Positives = 124/306 (40%), Gaps = 48/306 (15%)

Query: 1008 PSPSLQPSFNPGKTPARSTHSEAPPSKMVLRIPHPIQPATVLQTVPGVP-PLGVSGGESF 1066
            P P LQP       P+  +H++ P        PH +Q   +LQ  PG P P G+   ++ 
Sbjct: 268  PHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQH-PGPPQPFGLP-PQAS 325

Query: 1067 ESPAALPAVPPEA--RTSFPLSESQTLLSSAPVPKVMLPSLAPSKFRKPYVRRRPSKRRG 1124
            +  A L   P  A   TS  L  SQ+ L S   P+     L P+    P+++  P+    
Sbjct: 326  QGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQ--PLPPAPLAMPHIKPPPT---- 379

Query: 1125 VKASPCMK-PAPVIH-HPASVIFTVPATTVKIVSLGGGCNMIQPVNAAVAQSPQTIPITT 1182
               +P  + PAP  H HP  +    P +                +NA +   P   P+++
Sbjct: 380  ---TPIPQLPAPQAHKHPPHLSGPSPFS----------------MNANLPPPPALKPLSS 420

Query: 1183 LLVN--PTSFPCPL-----NQSLVASSVSPLIVSGNSVNLPIP--STPEDKAHVNVDIAC 1233
            L  +  P++ P PL     +Q L +S   P  ++  S NLP P  S P    H    +A 
Sbjct: 421  LSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT-QSQNLPPPPASHPPTGLH---QVAP 476

Query: 1234 AVADGENAF-QGLEPKLEPQELSPLSATVFPKVEHSPGPPLADAECQEG-LSENSACRWT 1291
                 ++ F  G  P + P    P ++T       S  PP + A    G ++  S+C   
Sbjct: 477  QPPFAQHPFVPGGPPPITP-PTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLP 535

Query: 1292 VVKTEE 1297
             V+ +E
Sbjct: 536  TVQIKE 541



 Score = 34.3 bits (77), Expect = 0.95
 Identities = 29/131 (22%), Positives = 48/131 (36%), Gaps = 7/131 (5%)

Query: 1358 TGAPSEELSSAGEVTKQTVLQKEEERSQPTKTPSSSQEPPDEGTSGTDVNKGSSKNALSS 1417
            + A +    S  E  K++  + +EE S P K+    +E     T   D    S K     
Sbjct: 61   SAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEAD-RTSSKKTKTQE 119

Query: 1418 MDPEVRLSSPPGKPEDSSSVDGQSVGTPVGPETGGEKNGPEEEEEEDFDDLTQDEEDEMS 1477
            +      S   G+  DS SV+ +    P   +       P     +D      +E D  S
Sbjct: 120  ISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQD------NESDSDS 173

Query: 1478 SASEESVLSVP 1488
            SA ++ + + P
Sbjct: 174  SAQQQMLQAQP 184



 Score = 33.1 bits (74), Expect = 2.1
 Identities = 32/114 (28%), Positives = 50/114 (43%), Gaps = 11/114 (9%)

Query: 1010 PSLQPSFNPGKTPARSTHSEAPPSKMVLRIPHPIQPATVLQTVPGVPPLGVSGGESFESP 1069
            PS Q + +   + A+    +A P    L+ P  + PA      PG P L   G     +P
Sbjct: 162  PSPQDNESDSDSSAQQQMLQAQPP--ALQAPTGVTPAPS-SAPPGTPQLPTPG----PTP 214

Query: 1070 AALPAVPPEARTSFPLSESQTLLSSAPVPKVML---PSLAPSKFRKPYVRRRPS 1120
            +A  AVPP+   +   + +Q    +APVP   +   P+L P +   P+    PS
Sbjct: 215  SAT-AVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPS 267


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 45.1 bits (105), Expect = 5e-04
 Identities = 79/306 (25%), Positives = 124/306 (40%), Gaps = 48/306 (15%)

Query: 1008 PSPSLQPSFNPGKTPARSTHSEAPPSKMVLRIPHPIQPATVLQTVPGVP-PLGVSGGESF 1066
            P P LQP       P+  +H++ P        PH +Q   +LQ  PG P P G+   ++ 
Sbjct: 822  PHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQH-PGPPQPFGLP-PQAS 879

Query: 1067 ESPAALPAVPPEA--RTSFPLSESQTLLSSAPVPKVMLPSLAPSKFRKPYVRRRPSKRRG 1124
            +  A L   P  A   TS  L  SQ+ L S   P+     L P+    P+++  P+    
Sbjct: 880  QGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQ--PLPPAPLAMPHIKPPPT---- 933

Query: 1125 VKASPCMK-PAPVIH-HPASVIFTVPATTVKIVSLGGGCNMIQPVNAAVAQSPQTIPITT 1182
               +P  + PAP  H HP  +    P +                +NA +   P   P+++
Sbjct: 934  ---TPIPQLPAPQAHKHPPHLSGPSPFS----------------MNANLPPPPALKPLSS 974

Query: 1183 LLVN--PTSFPCPL-----NQSLVASSVSPLIVSGNSVNLPIP--STPEDKAHVNVDIAC 1233
            L  +  P++ P PL     +Q L +S   P  ++  S NLP P  S P    H    +A 
Sbjct: 975  LSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT-QSQNLPPPPASHPPTGLH---QVAP 1030

Query: 1234 AVADGENAF-QGLEPKLEPQELSPLSATVFPKVEHSPGPPLADAECQEG-LSENSACRWT 1291
                 ++ F  G  P + P    P ++T       S  PP + A    G ++  S+C   
Sbjct: 1031 QPPFAQHPFVPGGPPPITP-PTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLP 1089

Query: 1292 VVKTEE 1297
             V+ +E
Sbjct: 1090 TVQIKE 1095



 Score = 34.3 bits (77), Expect = 0.95
 Identities = 29/131 (22%), Positives = 48/131 (36%), Gaps = 7/131 (5%)

Query: 1358 TGAPSEELSSAGEVTKQTVLQKEEERSQPTKTPSSSQEPPDEGTSGTDVNKGSSKNALSS 1417
            + A +    S  E  K++  + +EE S P K+    +E     T   D    S K     
Sbjct: 615  SAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEAD-RTSSKKTKTQE 673

Query: 1418 MDPEVRLSSPPGKPEDSSSVDGQSVGTPVGPETGGEKNGPEEEEEEDFDDLTQDEEDEMS 1477
            +      S   G+  DS SV+ +    P   +       P     +D      +E D  S
Sbjct: 674  ISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQD------NESDSDS 727

Query: 1478 SASEESVLSVP 1488
            SA ++ + + P
Sbjct: 728  SAQQQMLQAQP 738



 Score = 33.1 bits (74), Expect = 2.1
 Identities = 32/114 (28%), Positives = 50/114 (43%), Gaps = 11/114 (9%)

Query: 1010 PSLQPSFNPGKTPARSTHSEAPPSKMVLRIPHPIQPATVLQTVPGVPPLGVSGGESFESP 1069
            PS Q + +   + A+    +A P    L+ P  + PA      PG P L   G     +P
Sbjct: 716  PSPQDNESDSDSSAQQQMLQAQPP--ALQAPTGVTPAPS-SAPPGTPQLPTPG----PTP 768

Query: 1070 AALPAVPPEARTSFPLSESQTLLSSAPVPKVML---PSLAPSKFRKPYVRRRPS 1120
            +A  AVPP+   +   + +Q    +APVP   +   P+L P +   P+    PS
Sbjct: 769  SAT-AVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPS 821


>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 45.1 bits (105), Expect = 5e-04
 Identities = 79/306 (25%), Positives = 124/306 (40%), Gaps = 48/306 (15%)

Query: 1008 PSPSLQPSFNPGKTPARSTHSEAPPSKMVLRIPHPIQPATVLQTVPGVP-PLGVSGGESF 1066
            P P LQP       P+  +H++ P        PH +Q   +LQ  PG P P G+   ++ 
Sbjct: 822  PHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQH-PGPPQPFGLP-PQAS 879

Query: 1067 ESPAALPAVPPEA--RTSFPLSESQTLLSSAPVPKVMLPSLAPSKFRKPYVRRRPSKRRG 1124
            +  A L   P  A   TS  L  SQ+ L S   P+     L P+    P+++  P+    
Sbjct: 880  QGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQ--PLPPAPLAMPHIKPPPT---- 933

Query: 1125 VKASPCMK-PAPVIH-HPASVIFTVPATTVKIVSLGGGCNMIQPVNAAVAQSPQTIPITT 1182
               +P  + PAP  H HP  +    P +                +NA +   P   P+++
Sbjct: 934  ---TPIPQLPAPQAHKHPPHLSGPSPFS----------------MNANLPPPPALKPLSS 974

Query: 1183 LLVN--PTSFPCPL-----NQSLVASSVSPLIVSGNSVNLPIP--STPEDKAHVNVDIAC 1233
            L  +  P++ P PL     +Q L +S   P  ++  S NLP P  S P    H    +A 
Sbjct: 975  LSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT-QSQNLPPPPASHPPTGLH---QVAP 1030

Query: 1234 AVADGENAF-QGLEPKLEPQELSPLSATVFPKVEHSPGPPLADAECQEG-LSENSACRWT 1291
                 ++ F  G  P + P    P ++T       S  PP + A    G ++  S+C   
Sbjct: 1031 QPPFAQHPFVPGGPPPITP-PTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLP 1089

Query: 1292 VVKTEE 1297
             V+ +E
Sbjct: 1090 TVQIKE 1095



 Score = 34.3 bits (77), Expect = 0.95
 Identities = 29/131 (22%), Positives = 48/131 (36%), Gaps = 7/131 (5%)

Query: 1358 TGAPSEELSSAGEVTKQTVLQKEEERSQPTKTPSSSQEPPDEGTSGTDVNKGSSKNALSS 1417
            + A +    S  E  K++  + +EE S P K+    +E     T   D    S K     
Sbjct: 615  SAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEAD-RTSSKKTKTQE 673

Query: 1418 MDPEVRLSSPPGKPEDSSSVDGQSVGTPVGPETGGEKNGPEEEEEEDFDDLTQDEEDEMS 1477
            +      S   G+  DS SV+ +    P   +       P     +D      +E D  S
Sbjct: 674  ISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQD------NESDSDS 727

Query: 1478 SASEESVLSVP 1488
            SA ++ + + P
Sbjct: 728  SAQQQMLQAQP 738



 Score = 33.1 bits (74), Expect = 2.1
 Identities = 32/114 (28%), Positives = 50/114 (43%), Gaps = 11/114 (9%)

Query: 1010 PSLQPSFNPGKTPARSTHSEAPPSKMVLRIPHPIQPATVLQTVPGVPPLGVSGGESFESP 1069
            PS Q + +   + A+    +A P    L+ P  + PA      PG P L   G     +P
Sbjct: 716  PSPQDNESDSDSSAQQQMLQAQPP--ALQAPTGVTPAPS-SAPPGTPQLPTPG----PTP 768

Query: 1070 AALPAVPPEARTSFPLSESQTLLSSAPVPKVML---PSLAPSKFRKPYVRRRPS 1120
            +A  AVPP+   +   + +Q    +APVP   +   P+L P +   P+    PS
Sbjct: 769  SAT-AVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPS 821


>gi|21361639 DIPB protein [Homo sapiens]
          Length = 344

 Score = 44.7 bits (104), Expect = 7e-04
 Identities = 33/84 (39%), Positives = 44/84 (52%), Gaps = 4/84 (4%)

Query: 349 KKANEIKPPQFVDIHLEEDDSSDEEYQPDDEEEDETAEESLLESDVESTASSPRGAKKSR 408
           K+  E+K  Q  +I  E  + S+ E + + EEE ET EES  ESD ES   S    ++  
Sbjct: 78  KEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDS---EEEME 134

Query: 409 LRQSSEMTETDEESGILSEAEKVT 432
             Q SE  E ++E G  SEAE  T
Sbjct: 135 DEQESEAEEDNQEEG-ESEAEGET 157



 Score = 33.1 bits (74), Expect = 2.1
 Identities = 18/67 (26%), Positives = 32/67 (47%)

Query: 365 EEDDSSDEEYQPDDEEEDETAEESLLESDVESTASSPRGAKKSRLRQSSEMTETDEESGI 424
           EE+  ++EE + + +EE E   E  +E + ES A      +     +     E++ +  I
Sbjct: 108 EEESETEEESEDESDEESEEDSEEEMEDEQESEAEEDNQEEGESEAEGETEAESEFDPEI 167

Query: 425 LSEAEKV 431
             EAE+V
Sbjct: 168 EMEAERV 174


>gi|109637791 transcription factor-like nuclear regulator [Homo
            sapiens]
          Length = 2624

 Score = 44.7 bits (104), Expect = 7e-04
 Identities = 83/430 (19%), Positives = 181/430 (42%), Gaps = 57/430 (13%)

Query: 268  KLDDMLDRTLEDGAKQHNLTAVNVRNILHEVITNEHVVAMMKAAISETEDMPMFEPKMTR 327
            K+ D++D T+E    +  L A+     L E      V+   +    + E+    E    +
Sbjct: 887  KILDVIDDTIE---METGLKAMGREICLRE--KTPEVIDATEEIDKDLEEAGRREISPQK 941

Query: 328  SKLKEVVEKGVVIPTWNISPIKKANEIKPPQFVDIHLEEDDSSDE----EYQPDDEEEDE 383
            +  +EV   G V      +  + +   K P+  D   E D + +E    +  P +   +E
Sbjct: 942  NGPEEVKPLGEVETDLKATGNESSPREKTPEVTDATEEIDKNLEETGRRKISPRENGPEE 1001

Query: 384  TAEESLLESDVESTASSPRGAKKSRLRQSSEMTETDEESGILSEAEKVTTPAIRHISAEV 443
                  +E+D+ +T     G + S   ++ E+ +  EE   L E E+  +P    +  EV
Sbjct: 1002 VKPVDEMETDLNAT-----GRESSPREKTPEVIDATEEID-LEETEREVSPQENGLE-EV 1054

Query: 444  VPMGPPPPPKPKQTRDSTFMEKLHAVDEELASSPVCMDSFQ----PMDDSLIAFRTRSKM 499
             P+G          RDS    K   V + +    + ++  +    P ++ L   +     
Sbjct: 1055 KPLGEMETDLKATGRDSFPRGKTPEVIDAIEEIEIDLEETEREISPQENGLEEVK----- 1109

Query: 500  PLKDVPLGQLEAELQAP-------DITPDMYDPNTADDEDWKMWLGGLMNDDVGNEDEAD 552
                 PLG+++ +L+A        + TP++ D     D+D          ++ G  + + 
Sbjct: 1110 -----PLGEMQTDLKATGREISPREKTPEVIDATEEIDKDL---------EETGRREISP 1155

Query: 553  DDDDPEYNFLEDLDEPDTEDFRTDRAVRITKKEVNELME--ELFETFQDEMGFS-NMEDD 609
            +++ PE   ++ +DE +T D +T      ++++  E+++  E+ ET  +E     + +++
Sbjct: 1156 EENGPEE--VKPVDEMET-DLKTTGREGSSREKTREVIDAAEVIETDLEETEREISPQEN 1212

Query: 610  GPEEEECVAEPRPNFNTPQALRFEEPLANLLNEQHRTVKELFEQLKMKKSSAKQLQEVEK 669
            GPEE + V +   +    + +R E      +  +   ++E  +++ +K++  + +  +EK
Sbjct: 1213 GPEEVKPVGKMETDL---KEIREEISQREKVLAEFSAIRE--KEIDLKETGKRDIPIMEK 1267

Query: 670  VKPQSEKVHQ 679
            V  +   V +
Sbjct: 1268 VSGKMAVVEE 1277



 Score = 33.5 bits (75), Expect = 1.6
 Identities = 83/381 (21%), Positives = 151/381 (39%), Gaps = 57/381 (14%)

Query: 153  KEPFSGEPSEEVK---EEGGK----PQMNSEGEIPSLPSGSQSAKPV---SQPRKSTQPD 202
            K P   + +EE+    EE G+    PQ N   E+  L       K     S PR+ T P+
Sbjct: 914  KTPEVIDATEEIDKDLEEAGRREISPQKNGPEEVKPLGEVETDLKATGNESSPREKT-PE 972

Query: 203  VCASPQE--KPLRTLFHQPEEEIEDGGLFIPMEEQ--DNEESEKRRKKKKGTKRKRDGRG 258
            V  + +E  K L     +     E+G    P E +  D  E++     ++ + R++    
Sbjct: 973  VTDATEEIDKNLEETGRRKISPRENG----PEEVKPVDEMETDLNATGRESSPREKTPEV 1028

Query: 259  QEGTLAYDLK--------LDDMLDRTLEDGAKQHNLTAVNVRNILHEVITNEHVVAMMKA 310
             + T   DL+         ++ L+     G  + +L A   R+      T E + A+ + 
Sbjct: 1029 IDATEEIDLEETEREVSPQENGLEEVKPLGEMETDLKATG-RDSFPRGKTPEVIDAIEEI 1087

Query: 311  AISETEDMPMFEPKMTRSKLKEVVEKGVVIPTWNISPIKKANEIKPPQFVDIHLEEDDSS 370
             I   E      P+   + L+EV   G +      +  + +   K P+ +D   E D   
Sbjct: 1088 EIDLEETEREISPQ--ENGLEEVKPLGEMQTDLKATGREISPREKTPEVIDATEEIDKDL 1145

Query: 371  DE----EYQPDDEEEDETAEESLLESDVESTASSPRGAKKSR-LRQSSEMTETDEESGIL 425
            +E    E  P++   +E      +E+D+++T       +K+R +  ++E+ ETD     L
Sbjct: 1146 EETGRREISPEENGPEEVKPVDEMETDLKTTGREGSSREKTREVIDAAEVIETD-----L 1200

Query: 426  SEAEKVTTPAIRHISAEVVPMGPPPPPKPKQTRDSTFMEKLHAVDEELASSPVCMDSFQP 485
             E E+  +P   +   EV P+G       K   D      L  + EE++     +  F  
Sbjct: 1201 EETEREISPQ-ENGPEEVKPVG-------KMETD------LKEIREEISQREKVLAEFSA 1246

Query: 486  MDDSLIAFRTRSKMPLKDVPL 506
            + +  I  +   K   +D+P+
Sbjct: 1247 IREKEIDLKETGK---RDIPI 1264



 Score = 32.3 bits (72), Expect = 3.6
 Identities = 51/256 (19%), Positives = 93/256 (36%), Gaps = 41/256 (16%)

Query: 1251 PQELSPLS-------ATVFPKVEHSPGPPLADA--ECQEGLSENSACRWTVVKTEEGRQA 1301
            P+E+ PL        AT          P + DA  E  + L E    R  +   E G + 
Sbjct: 944  PEEVKPLGEVETDLKATGNESSPREKTPEVTDATEEIDKNLEETG--RRKISPRENGPEE 1001

Query: 1302 LEPLPQ--------GIQESLNNPTPGDLEEIVKMEPEEAREEISGSPERDICDDIKVEHA 1353
            ++P+ +        G + S    TP  ++   +++ EE   E+S  P+ +  +++K    
Sbjct: 1002 VKPVDEMETDLNATGRESSPREKTPEVIDATEEIDLEETEREVS--PQENGLEEVKPLGE 1059

Query: 1354 VELDTGAPSEELSSAG------EVTKQTVLQKEEERSQPTKTPSSSQEPPDEGTSGTDVN 1407
            +E D  A   +    G      +  ++  +  EE   + +   +  +E    G   TD+ 
Sbjct: 1060 METDLKATGRDSFPRGKTPEVIDAIEEIEIDLEETEREISPQENGLEEVKPLGEMQTDLK 1119

Query: 1408 KGSSKNALSSMDPEVRLSSPPGKPEDSSSVDGQSVGTPVGPETGGEKNGPEEEEEEDFDD 1467
                + +     PEV              +D          ETG  +  PEE   E+   
Sbjct: 1120 ATGREISPREKTPEV--------------IDATEEIDKDLEETGRREISPEENGPEEVKP 1165

Query: 1468 LTQDEEDEMSSASEES 1483
            + + E D  ++  E S
Sbjct: 1166 VDEMETDLKTTGREGS 1181


>gi|18093112 ABT1-associated protein [Homo sapiens]
          Length = 851

 Score = 44.7 bits (104), Expect = 7e-04
 Identities = 58/295 (19%), Positives = 123/295 (41%), Gaps = 34/295 (11%)

Query: 347 PIKKANEIKPPQFVDIHLEEDDSSDEEYQPDDEEEDETAE-ESLLESDVESTASSPRGAK 405
           PI  +      +F D+   + + S E+ +   +++ +  + ++  E D ++     +  K
Sbjct: 59  PISHSTTEDLKRFYDLSDSDSNLSGEDSKALSQKKIKKKKTQTKKEIDSKNLVEKKKETK 118

Query: 406 KSRLRQSSEMTETDEESGILSEAEKVTTPAIRHISAEVVPMGPPPPPKPKQ--------- 456
           K+  + S   T+ D   GI    +K+ T     I + + P         K          
Sbjct: 119 KANHKGSENKTDLDNSIGI----KKMKTSCKFKIDSNISPKKDSKEFTQKNKKEKKNIVQ 174

Query: 457 -TRDSTFMEKLHAVDE---ELASSP--VCMDSFQPMDDSLIAFRTRSKMPLKDVPLGQLE 510
            T DS+  EK   +D    E+  SP   C  + + M   +    TR     ++   G++ 
Sbjct: 175 HTTDSSLEEKQRTLDSGTSEIVKSPRIECSKTRREMQSVVQLIMTRDSDGYENSTDGEMC 234

Query: 511 AELQAPDITPDMYDPNTADDEDWKMW-LGGLMNDDVGNEDEADDDDDPEYNFLEDLDEPD 569
            +    + +  + +  + ++ + ++  +G    DD G+ED+ ++D+D E    ED DE  
Sbjct: 235 DKDALEEDSESVSEIGSDEESENEITSVGRASGDDDGSEDDEEEDEDEE----EDEDEDS 290

Query: 570 TEDFRTDRAVRITKKEVN-----ELMEELFETFQDEMGFSN----MEDDGPEEEE 615
            +D ++D    + + + N     E  ++  + F +E GF +    ++ D P  +E
Sbjct: 291 EDDDKSDSGPDLARGKGNIETSSEDEDDTADLFPEESGFEHAWRELDKDAPRADE 345



 Score = 34.3 bits (77), Expect = 0.95
 Identities = 26/116 (22%), Positives = 49/116 (42%), Gaps = 4/116 (3%)

Query: 1366 SSAGEVTKQTVLQKEEERSQPTKTPSSSQEPPDEGTSGTDVNKGSSKNALSSMDPEVRLS 1425
            S   E+ K   ++  + R +             +G   +   +   K+AL      V   
Sbjct: 190  SGTSEIVKSPRIECSKTRREMQSVVQLIMTRDSDGYENSTDGEMCDKDALEEDSESV--- 246

Query: 1426 SPPGKPEDSSSVDGQSVGTPVGPETGGEKNGPEEEEEEDFDDLTQDEEDEMSSASE 1481
            S  G  E+S + +  SVG   G + G E +  E+E+EE+ +D   +++D+  S  +
Sbjct: 247  SEIGSDEESEN-EITSVGRASGDDDGSEDDEEEDEDEEEDEDEDSEDDDKSDSGPD 301



 Score = 32.0 bits (71), Expect = 4.7
 Identities = 44/195 (22%), Positives = 85/195 (43%), Gaps = 35/195 (17%)

Query: 1320 DLEEIVKMEPEEAREEISGSPERDICDD------IKVEHAVELDTGAP----SEELSSAG 1369
            D + +V+ + E  +    GS  +   D+      +K     ++D+       S+E +   
Sbjct: 106  DSKNLVEKKKETKKANHKGSENKTDLDNSIGIKKMKTSCKFKIDSNISPKKDSKEFTQKN 165

Query: 1370 EVTKQTVLQ-------KEEERSQPTKTPSSSQEPPDEGTSGTDVNKGSSKNALSSMDPEV 1422
            +  K+ ++Q       +E++R+  + T    + P  E  S T     S    + + D + 
Sbjct: 166  KKEKKNIVQHTTDSSLEEKQRTLDSGTSEIVKSPRIE-CSKTRREMQSVVQLIMTRDSDG 224

Query: 1423 RLSSPPGK-------PEDSSSV-------DGQSVGTPVGPETGGEKNGPEEEEEEDFDDL 1468
              +S  G+        EDS SV       + ++  T VG    G+ +G E++EEED D+ 
Sbjct: 225  YENSTDGEMCDKDALEEDSESVSEIGSDEESENEITSVG-RASGDDDGSEDDEEEDEDE- 282

Query: 1469 TQDEEDEMSSASEES 1483
             +++EDE S   ++S
Sbjct: 283  -EEDEDEDSEDDDKS 296


>gi|157738619 smoothelin-like 1 [Homo sapiens]
          Length = 512

 Score = 44.7 bits (104), Expect = 7e-04
 Identities = 59/261 (22%), Positives = 103/261 (39%), Gaps = 42/261 (16%)

Query: 1234 AVADGENAFQGLEPKLEPQE--LSPLSATVFPKVEHSP----GPPLADAECQEGLSENSA 1287
            AV + + + +  E K+E +E  LS    TV P  ++      G P  + +   G + N  
Sbjct: 5    AVGESDCSAEARE-KMEQKEGKLSEDGTTVSPAADNPEMSGGGAPAEETKGTAGKAINEG 63

Query: 1288 CRWTVVKTEEGRQALEPLPQGIQESLNNPTPGDLEEIVKMEPEEAREEISGSPERDICDD 1347
                   TE G+Q   P   G+   L     G L+E+      E++ E  G  + +   +
Sbjct: 64   -----PPTESGKQEKAPAEDGMSAELQGEANG-LDEV----KVESQREAGGKEDAEA--E 111

Query: 1348 IKVEHAVELDTGAPSEELSSAGEVTKQTVLQKEEERSQPTKTPSSSQEPPDEGTSGTDVN 1407
            +K E   + +T   S+E++   E TK    + EE+ S        ++E   +  SG   +
Sbjct: 112  LKKEDGEKEETTVGSQEMTGRKEETKSEPKEAEEKESTLASEKQKAEEKEAKPESGQKAD 171

Query: 1408 KGSSKNALSSMDPEVRLSSPPGKPEDSSSVDGQSVGTPVGPETGGEKNGPEEEEEEDFDD 1467
                             ++   KPE  ++V+ +   T    ETG  K    E +E+  D+
Sbjct: 172  -----------------ANDRDKPEPKATVEEEDAKTASQEETGQRKECSTEPKEKATDE 214

Query: 1468 LTQDE------EDEMSSASEE 1482
              + E      EDE  +  +E
Sbjct: 215  EAKAESQKAVVEDEAKAEPKE 235



 Score = 31.2 bits (69), Expect = 8.0
 Identities = 52/291 (17%), Positives = 112/291 (38%), Gaps = 21/291 (7%)

Query: 157 SGEPSEEVKEEGGKPQMNSEGEIPSLPSGSQSAKPVSQPRKSTQPDVCASPQEKPLRTLF 216
           S E  E+++++ GK  ++ +G   S  + +        P + T+     +  E P     
Sbjct: 12  SAEAREKMEQKEGK--LSEDGTTVSPAADNPEMSGGGAPAEETKGTAGKAINEGPPTESG 69

Query: 217 HQPEEEIEDGGLFIPMEEQDNEESEKRRKKKKGTKRKRDGRGQEGTLAYDLKLDDMLDRT 276
            Q +   EDG +   ++ + N   E +       + +R+  G+E   A +LK +D     
Sbjct: 70  KQEKAPAEDG-MSAELQGEANGLDEVK------VESQREAGGKEDAEA-ELKKEDGEKEE 121

Query: 277 LEDGAKQHNLTAVNVRNILHEVITNEHVVAMMKAAISETEDMPMFEPKMTRSKLKEVVEK 336
              G+++        ++   E    E  +A  K    E E  P    K   +   +   K
Sbjct: 122 TTVGSQEMTGRKEETKSEPKEAEEKESTLASEKQKAEEKEAKPESGQKADANDRDKPEPK 181

Query: 337 GVVIPTWNISPIKKANEIKPPQFVDIHLEEDDSSDEEYQPDDEEEDETAEESLLESDVES 396
             V          +  + K     +    ++ S++ + +  DEE    ++++++E + ++
Sbjct: 182 ATV----------EEEDAKTASQEETGQRKECSTEPKEKATDEEAKAESQKAVVEDEAKA 231

Query: 397 TASSPRGAKKSRLRQSSEMTETDEESGILSEAEKVTTPAIRHISAEVVPMG 447
               P G ++++   + E  +  EE+    EAE  +    +    E  P G
Sbjct: 232 EPKEPDGKEEAK-HGAKEEADAKEEAEDAEEAEPGSPSEEQEQDVEKEPEG 281


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score = 44.3 bits (103), Expect = 0.001
 Identities = 59/278 (21%), Positives = 84/278 (30%), Gaps = 26/278 (9%)

Query: 1003 PLLIQPSPSLQPSFNPGKTPARSTHSEAPPSKMVLRIPHPIQPATVLQTVPGVPPLGVSG 1062
            P    PSP       P  TP+  T +   P       P    P T   +   +PP     
Sbjct: 1465 PPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPS 1524

Query: 1063 GESFESPAALPAVPPEARTSFPLSESQTLLSSAPVPKVMLPSLAPSKFRKPYVRRRPSKR 1122
              +  +    P   P   T+ P++      S+  +P    PS  P+    P     PS  
Sbjct: 1525 PPTTTTTTPPPTTTPSPPTTTPITPP---TSTTTLPPTTTPSPPPTTTTTPPPTTTPSPP 1581

Query: 1123 RGVKASPCMKPAPVIHHPASVIFTVPATTVKIVSLGGGCNMIQPVNAAVAQSPQTIPIT- 1181
                 SP   P      P       P TT              P        P T PIT 
Sbjct: 1582 TTTTPSP---PTITTTTPPPTTTPSPPTTTTTT----------PPPTTTPSPPTTTPITP 1628

Query: 1182 ---TLLVNPTSFPCPLNQSLV----ASSVSPLIVSGNSVNLPIPSTPEDKAHVNVDIACA 1234
               T  + PT+ P P   +       ++ SP   +  S  +   +TP      +  I   
Sbjct: 1629 PTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTT 1688

Query: 1235 VADGENAFQGLEPKLEPQELSPLSATVFPKVEHSPGPP 1272
             +          P   P   SP++ T  P    +P PP
Sbjct: 1689 PSPPTTTMTTPSPTTTPS--SPITTTTTPSSTTTPSPP 1724



 Score = 38.9 bits (89), Expect = 0.039
 Identities = 73/318 (22%), Positives = 112/318 (35%), Gaps = 68/318 (21%)

Query: 947  TTEINSDRSLEKDNLELGSESRYPLLLPKGVVLKLKPVATRFPRKAWRQKRSSVLKPLLI 1006
            TT I +  ++       G+++  P   P      + P  T  P        + +     +
Sbjct: 4083 TTPITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTV 4138

Query: 1007 QPSPSLQPSFNPGKTPARSTHSEAP-PSKMVLRIPHPIQPATVLQTVPGVPPLGVSGGES 1065
             P+P+   +  P  TP  +T +  P P+    + P      T     P   P G   G  
Sbjct: 4139 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPP 4198

Query: 1066 FESPAALPAV------PPEART-------SFPLSESQTLLSSAPVPKVMLPSLAPSKFRK 1112
              +  A  A       PPE+ T       S PL+ES TLLS+ P P + + S AP     
Sbjct: 4199 THTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLP-PAIEMTSTAP----- 4252

Query: 1113 PYVRRRPSKRRGVKASPCMKPAPVIHHPASVIFTVPATTVKIVSLGGGCNMIQPVNAAVA 1172
            P     P+   G            +  P S   + P T  +  + G          ++ A
Sbjct: 4253 PSTPTAPTTTSG---------GHTLSPPPSTTTSPPGTPTRGTTTG----------SSSA 4293

Query: 1173 QSPQTIPITTLLV-NPTSFPCPLNQSLVASSVSPLIVSGNSVNLPIPSTPEDKAHVNVDI 1231
             +P T+  TT     PT  P PL+        +P I+    +  P PS        +V I
Sbjct: 4294 PTPSTVQTTTTSAWTPT--PTPLS--------TPSIIRTTGLR-PYPS--------SVLI 4334

Query: 1232 ACAVAD-----GENAFQG 1244
             C + D     GE  + G
Sbjct: 4335 CCVLNDTYYAPGEEVYNG 4352



 Score = 36.6 bits (83), Expect = 0.19
 Identities = 43/184 (23%), Positives = 63/184 (34%), Gaps = 28/184 (15%)

Query: 1021 TPARSTHSEAPPSKMVLRIP---HPIQPATVLQTVPGV----PPLGVSGGESFESPAALP 1073
            TP+  T + +PP      +P    P  P T   T P      PP+  +   +   P   P
Sbjct: 1398 TPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTT---TTPPPTTTP 1454

Query: 1074 AVPPEARTSFPLSESQTLLSSAPVPKVMLPSLAPSKFRKPYVRRRPSKRRGVKASPCMKP 1133
            + P    T+ P + + +  ++ P P    PS   +    P     PS       +P   P
Sbjct: 1455 SPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSP---PTTTPITPP 1511

Query: 1134 APVIHHPASVIFTVPATTVKIVSLGGGCNMIQPVNAAVAQSPQTIPIT----TLLVNPTS 1189
            A     P +   + P TT              P        P T PIT    T  + PT+
Sbjct: 1512 ASTTTLPPTTTPSPPTTTT-----------TTPPPTTTPSPPTTTPITPPTSTTTLPPTT 1560

Query: 1190 FPCP 1193
             P P
Sbjct: 1561 TPSP 1564



 Score = 35.4 bits (80), Expect = 0.43
 Identities = 31/118 (26%), Positives = 47/118 (39%), Gaps = 18/118 (15%)

Query: 1008 PSPSLQPSFNPGKTPARSTHSEAPPSKMVLRIPHPIQPATVLQT-----VPGVPPLGVSG 1062
            P P+  PS     TP+  T +   PS        P  P T   T      P  PP  ++ 
Sbjct: 1675 PPPTTTPSSPITTTPSPPTTTMTTPSPTTT----PSSPITTTTTPSSTTTPSPPPTTMTT 1730

Query: 1063 GESFESPAALPAVPPEARTSFPLSESQTLLSSAPVPKVMLPSLAPSKFRKPYVRRRPS 1120
                 SP   P+ P    T+ P + + + L++ P+P    PS+ P  F  P+    P+
Sbjct: 1731 ----PSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLP----PSITPPTF-SPFSTTTPT 1779



 Score = 35.0 bits (79), Expect = 0.56
 Identities = 34/151 (22%), Positives = 50/151 (33%), Gaps = 14/151 (9%)

Query: 1003 PLLIQPSPSLQPSFNP--GKTPARSTHSEAPPSKMVLRIPHPIQPATVLQTVPGVPPLGV 1060
            P    PSP       P    T    T + +PP       P    P+    T P  P    
Sbjct: 1613 PPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTT 1672

Query: 1061 SGGESFESPAALPAVPPEARTSFPLSESQTLLSSAPVPKVMLPSLAPSKFRKPYVRRRPS 1120
            +      +P++     P   T+   + S T   S+P+     PS   +    P     P 
Sbjct: 1673 TTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTP- 1731

Query: 1121 KRRGVKASPCMKPAPVIHHPASVIFTVPATT 1151
                   SP   P+P    P + + T+P TT
Sbjct: 1732 -------SPTTTPSP----PTTTMTTLPPTT 1751


>gi|114205399 cyclic nucleotide gated channel beta 1 isoform a [Homo
           sapiens]
          Length = 1251

 Score = 43.9 bits (102), Expect = 0.001
 Identities = 71/314 (22%), Positives = 111/314 (35%), Gaps = 57/314 (18%)

Query: 350 KANEIKPPQFVDIHLEEDDSSDEEYQPDDEEEDETAEESLLESDV---------ESTASS 400
           KA E  P +   I  E++D  +EE + ++EEE+E   E LL+S V         E   + 
Sbjct: 338 KAVEKMPRELSRIEEEKEDEEEEE-EEEEEEEEEEVTEVLLDSCVVSQVGVGQSEEDGTR 396

Query: 401 PRGAKKSRL---------RQSSEMTETDEESGILSEAEK-----VTTPAIRHISAEVVPM 446
           P+     +L         +++ E  + + E     EAEK       T       AE    
Sbjct: 397 PQSTSDQKLWEEVGEEAKKEAEEKAKEEAEEVAEEEAEKEPQDWAETKEEPEAEAEAASS 456

Query: 447 GPPPPPK-PKQTRDSTFMEKLHAVDEELASSPVCMDSFQPMDDSLIAFRT-----RSKMP 500
           G P   + P+   + T  +    + EE   S V         D+LI   +     R K+P
Sbjct: 457 GVPATKQHPEVQVEDTDADSCPLMAEENPPSTVLPPPSPAKSDTLIVPSSASGTHRKKLP 516

Query: 501 LKDVPLGQLEAELQAPDITPDMYDPNTADDEDWKMWLGGLMNDDVGNEDEADDDDDPEYN 560
            +D    +L+A   A        DP T  D D               +D A         
Sbjct: 517 SEDDEAEELKALSPAESPVVAWSDPTTPKDTD--------------GQDRAASTASTNSA 562

Query: 561 FLEDLDEPDTEDFRTDRAVRITKKEVNELMEELFETFQDEMGFSNMEDDGPEEEECVAEP 620
            + D         R    V++ K+   ++ E+L     D    S+ E   P   +   EP
Sbjct: 563 IIND---------RLQELVKLFKERTEKVKEKLI----DPDVTSDEESPKPSPAKKAPEP 609

Query: 621 RPNFNTPQALRFEE 634
            P+    +A   EE
Sbjct: 610 APDTKPAEAEPVEE 623


>gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]
          Length = 1682

 Score = 43.9 bits (102), Expect = 0.001
 Identities = 94/435 (21%), Positives = 145/435 (33%), Gaps = 63/435 (14%)

Query: 994  RQKRSSVLKPLLIQPSPSLQPSFNPGKTPARSTHSEAPPSKMVLR--IPHPIQPATVLQT 1051
            R +  S + P          PS  PG     ++ S +  S   LR   P+P  P      
Sbjct: 367  RSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQ 426

Query: 1052 VPGVPP-----LGVSGGESFESPAALPAVPPEARTSFPLSESQTLLSSAPVPKVMLPSLA 1106
             P +       LG S   S +     PA  P    S P   S       P P+++ P   
Sbjct: 427  TPALEVSHHGRLGPSAHSSRKPFLGAPAATPHL--SLPPGPSSP--PPPPCPRLLRPPPP 482

Query: 1107 PSKFRKPYVRRRPSKRR-------GVKASPCMKPAPVIHHPASVIFTVPATTVKIVSLGG 1159
            P+  + P  R              G +  P   P P+ H         PA+   + +   
Sbjct: 483  PAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREG--FLGPPASRFSVGTQDS 540

Query: 1160 GCNMIQPVNAAVAQSPQTIPITTLLVNPTSFPCPLNQSLVASSVSPLIVSGNSVNLPIPS 1219
                  P     + +  +   ++    P SFP P     +A S+ PL         P P+
Sbjct: 541  HTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPP---PYLARSIDPL------PRPPSPA 591

Query: 1220 -TPEDKAHVNVDIACAVADGENAFQGLEPKLEPQELSPLSATVFPKV-EHSPGPP----- 1272
              P+D   V + +A   A   +  Q         E SP     FPK  E  PGPP     
Sbjct: 592  QNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRRPE-SPRPRVSFPKTPEVGPGPPPGPLS 650

Query: 1273 LADAECQEGLSENSACRWTVVKTEEGRQALEPLPQGIQESLNNPT-----PGDLEEIVKM 1327
             A      G+ E  A          G +  +  P  +++    P      P  L  I+KM
Sbjct: 651  KAPQPVPPGVGELPA---------RGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKM 701

Query: 1328 -------EPEEAREEISGSPERDICDDI-KVEHAVELDTG----APSEELSSAGEVTKQT 1375
                   E E+ + E   +P+  + +    ++     DT     AP+  +++    T  T
Sbjct: 702  LDESIRKEEEQQQHEAGVAPQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTT 761

Query: 1376 VLQKEEERSQPTKTP 1390
               +EEE+  P   P
Sbjct: 762  TATQEEEKKPPPALP 776


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.129    0.371 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 68,480,549
Number of Sequences: 37866
Number of extensions: 3884552
Number of successful extensions: 31552
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 159
Number of HSP's successfully gapped in prelim test: 863
Number of HSP's that attempted gapping in prelim test: 21895
Number of HSP's gapped (non-prelim): 8246
length of query: 1529
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1414
effective length of database: 13,892,928
effective search space: 19644600192
effective search space used: 19644600192
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 69 (31.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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