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Search of human proteins with 77176455
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|77176455 DNA cytosine methyltransferase 3 alpha isoform b
[Homo sapiens]
(723 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|77176455 DNA cytosine methyltransferase 3 alpha isoform b [Ho... 1519 0.0
gi|12751473 DNA cytosine methyltransferase 3 alpha isoform a [Ho... 1471 0.0
gi|28559069 DNA cytosine methyltransferase 3 alpha isoform a [Ho... 1471 0.0
gi|28559065 DNA cytosine-5 methyltransferase 3 beta isoform 6 [H... 830 0.0
gi|28559061 DNA cytosine-5 methyltransferase 3 beta isoform 2 [H... 830 0.0
gi|5901940 DNA cytosine-5 methyltransferase 3 beta isoform 1 [Ho... 825 0.0
gi|28559063 DNA cytosine-5 methyltransferase 3 beta isoform 3 [H... 650 0.0
gi|28872780 cytosine-5-methyltransferase 3-like protein isoform ... 253 4e-67
gi|28872778 cytosine-5-methyltransferase 3-like protein isoform ... 253 6e-67
gi|148839376 PWWP domain containing 2 isoform 1 [Homo sapiens] 66 1e-10
gi|195963316 PWWP domain containing 2A isoform b [Homo sapiens] 57 5e-08
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 46 1e-04
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 45 2e-04
gi|110681712 hepatoma derived growth factor-like 1 [Homo sapiens] 42 0.002
gi|40556376 cytokine-like nuclear factor n-pac [Homo sapiens] 41 0.003
gi|38202209 methyl-CpG binding domain protein 5 [Homo sapiens] 39 0.013
gi|24308089 chromodomain helicase DNA binding protein 5 [Homo sa... 38 0.038
gi|13699811 WHSC1L1 protein isoform long [Homo sapiens] 38 0.038
gi|13699813 WHSC1L1 protein isoform short [Homo sapiens] 38 0.038
gi|51599156 chromodomain helicase DNA binding protein 4 [Homo sa... 36 0.11
gi|52630326 chromodomain helicase DNA binding protein 3 isoform ... 36 0.11
gi|52630322 chromodomain helicase DNA binding protein 3 isoform ... 36 0.11
gi|158420731 chromodomain helicase DNA binding protein 3 isoform... 36 0.11
gi|126723060 zinc finger CCCH-type containing 4 [Homo sapiens] 36 0.14
gi|4504191 mutS homolog 6 [Homo sapiens] 35 0.24
gi|14249464 zinc finger and BTB domain containing 45 [Homo sapiens] 34 0.42
gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens] 34 0.54
gi|56549129 transmembrane anchor protein 1 isoform 3 [Homo sapiens] 34 0.54
gi|56549133 transmembrane anchor protein 1 isoform 2 [Homo sapiens] 34 0.54
gi|56549131 transmembrane anchor protein 1 isoform 1 [Homo sapiens] 34 0.54
>gi|77176455 DNA cytosine methyltransferase 3 alpha isoform b [Homo
sapiens]
Length = 723
Score = 1519 bits (3932), Expect = 0.0
Identities = 723/723 (100%), Positives = 723/723 (100%)
Query: 1 MGILERVVRRNGRVDRSLKDECDTAEKKAKVIAGMNAVEENQGPGESQKVEEASPPAVQQ 60
MGILERVVRRNGRVDRSLKDECDTAEKKAKVIAGMNAVEENQGPGESQKVEEASPPAVQQ
Sbjct: 1 MGILERVVRRNGRVDRSLKDECDTAEKKAKVIAGMNAVEENQGPGESQKVEEASPPAVQQ 60
Query: 61 PTDPASPTVATTPEPVGSDAGDKNATKAGDDEPEYEDGRGFGIGELVWGKLRGFSWWPGR 120
PTDPASPTVATTPEPVGSDAGDKNATKAGDDEPEYEDGRGFGIGELVWGKLRGFSWWPGR
Sbjct: 61 PTDPASPTVATTPEPVGSDAGDKNATKAGDDEPEYEDGRGFGIGELVWGKLRGFSWWPGR 120
Query: 121 IVSWWMTGRSRAAEGTRWVMWFGDGKFSVVCVEKLMPLSSFCSAFHQATYNKQPMYRKAI 180
IVSWWMTGRSRAAEGTRWVMWFGDGKFSVVCVEKLMPLSSFCSAFHQATYNKQPMYRKAI
Sbjct: 121 IVSWWMTGRSRAAEGTRWVMWFGDGKFSVVCVEKLMPLSSFCSAFHQATYNKQPMYRKAI 180
Query: 181 YEVLQVASSRAGKLFPVCHDSDESDTAKAVEVQNKPMIEWALGGFQPSGPKGLEPPEEEK 240
YEVLQVASSRAGKLFPVCHDSDESDTAKAVEVQNKPMIEWALGGFQPSGPKGLEPPEEEK
Sbjct: 181 YEVLQVASSRAGKLFPVCHDSDESDTAKAVEVQNKPMIEWALGGFQPSGPKGLEPPEEEK 240
Query: 241 NPYKEVYTDMWVEPEAAAYAPPPPAKKPRKSTAEKPKVKEIIDERTRERLVYEVRQKCRN 300
NPYKEVYTDMWVEPEAAAYAPPPPAKKPRKSTAEKPKVKEIIDERTRERLVYEVRQKCRN
Sbjct: 241 NPYKEVYTDMWVEPEAAAYAPPPPAKKPRKSTAEKPKVKEIIDERTRERLVYEVRQKCRN 300
Query: 301 IEDICISCGSLNVTLEHPLFVGGMCQNCKNCFLECAYQYDDDGYQSYCTICCGGREVLMC 360
IEDICISCGSLNVTLEHPLFVGGMCQNCKNCFLECAYQYDDDGYQSYCTICCGGREVLMC
Sbjct: 301 IEDICISCGSLNVTLEHPLFVGGMCQNCKNCFLECAYQYDDDGYQSYCTICCGGREVLMC 360
Query: 361 GNNNCCRCFCVECVDLLVGPGAAQAAIKEDPWNCYMCGHKGTYGLLRRREDWPSRLQMFF 420
GNNNCCRCFCVECVDLLVGPGAAQAAIKEDPWNCYMCGHKGTYGLLRRREDWPSRLQMFF
Sbjct: 361 GNNNCCRCFCVECVDLLVGPGAAQAAIKEDPWNCYMCGHKGTYGLLRRREDWPSRLQMFF 420
Query: 421 ANNHDQEFDPPKVYPPVPAEKRKPIRVLSLFDGIATGLLVLKDLGIQVDRYIASEVCEDS 480
ANNHDQEFDPPKVYPPVPAEKRKPIRVLSLFDGIATGLLVLKDLGIQVDRYIASEVCEDS
Sbjct: 421 ANNHDQEFDPPKVYPPVPAEKRKPIRVLSLFDGIATGLLVLKDLGIQVDRYIASEVCEDS 480
Query: 481 ITVGMVRHQGKIMYVGDVRSVTQKHIQEWGPFDLVIGGSPCNDLSIVNPARKGLYEGTGR 540
ITVGMVRHQGKIMYVGDVRSVTQKHIQEWGPFDLVIGGSPCNDLSIVNPARKGLYEGTGR
Sbjct: 481 ITVGMVRHQGKIMYVGDVRSVTQKHIQEWGPFDLVIGGSPCNDLSIVNPARKGLYEGTGR 540
Query: 541 LFFEFYRLLHDARPKEGDDRPFFWLFENVVAMGVSDKRDISRFLESNPVMIDAKEVSAAH 600
LFFEFYRLLHDARPKEGDDRPFFWLFENVVAMGVSDKRDISRFLESNPVMIDAKEVSAAH
Sbjct: 541 LFFEFYRLLHDARPKEGDDRPFFWLFENVVAMGVSDKRDISRFLESNPVMIDAKEVSAAH 600
Query: 601 RARYFWGNLPGMNRPLASTVNDKLELQECLEHGRIAKFSKVRTITTRSNSIKQGKDQHFP 660
RARYFWGNLPGMNRPLASTVNDKLELQECLEHGRIAKFSKVRTITTRSNSIKQGKDQHFP
Sbjct: 601 RARYFWGNLPGMNRPLASTVNDKLELQECLEHGRIAKFSKVRTITTRSNSIKQGKDQHFP 660
Query: 661 VFMNEKEDILWCTEMERVFGFPVHYTDVSNMSRLARQRLLGRSWSVPVIRHLFAPLKEYF 720
VFMNEKEDILWCTEMERVFGFPVHYTDVSNMSRLARQRLLGRSWSVPVIRHLFAPLKEYF
Sbjct: 661 VFMNEKEDILWCTEMERVFGFPVHYTDVSNMSRLARQRLLGRSWSVPVIRHLFAPLKEYF 720
Query: 721 ACV 723
ACV
Sbjct: 721 ACV 723
>gi|12751473 DNA cytosine methyltransferase 3 alpha isoform a [Homo
sapiens]
Length = 912
Score = 1471 bits (3809), Expect = 0.0
Identities = 699/699 (100%), Positives = 699/699 (100%)
Query: 25 AEKKAKVIAGMNAVEENQGPGESQKVEEASPPAVQQPTDPASPTVATTPEPVGSDAGDKN 84
AEKKAKVIAGMNAVEENQGPGESQKVEEASPPAVQQPTDPASPTVATTPEPVGSDAGDKN
Sbjct: 214 AEKKAKVIAGMNAVEENQGPGESQKVEEASPPAVQQPTDPASPTVATTPEPVGSDAGDKN 273
Query: 85 ATKAGDDEPEYEDGRGFGIGELVWGKLRGFSWWPGRIVSWWMTGRSRAAEGTRWVMWFGD 144
ATKAGDDEPEYEDGRGFGIGELVWGKLRGFSWWPGRIVSWWMTGRSRAAEGTRWVMWFGD
Sbjct: 274 ATKAGDDEPEYEDGRGFGIGELVWGKLRGFSWWPGRIVSWWMTGRSRAAEGTRWVMWFGD 333
Query: 145 GKFSVVCVEKLMPLSSFCSAFHQATYNKQPMYRKAIYEVLQVASSRAGKLFPVCHDSDES 204
GKFSVVCVEKLMPLSSFCSAFHQATYNKQPMYRKAIYEVLQVASSRAGKLFPVCHDSDES
Sbjct: 334 GKFSVVCVEKLMPLSSFCSAFHQATYNKQPMYRKAIYEVLQVASSRAGKLFPVCHDSDES 393
Query: 205 DTAKAVEVQNKPMIEWALGGFQPSGPKGLEPPEEEKNPYKEVYTDMWVEPEAAAYAPPPP 264
DTAKAVEVQNKPMIEWALGGFQPSGPKGLEPPEEEKNPYKEVYTDMWVEPEAAAYAPPPP
Sbjct: 394 DTAKAVEVQNKPMIEWALGGFQPSGPKGLEPPEEEKNPYKEVYTDMWVEPEAAAYAPPPP 453
Query: 265 AKKPRKSTAEKPKVKEIIDERTRERLVYEVRQKCRNIEDICISCGSLNVTLEHPLFVGGM 324
AKKPRKSTAEKPKVKEIIDERTRERLVYEVRQKCRNIEDICISCGSLNVTLEHPLFVGGM
Sbjct: 454 AKKPRKSTAEKPKVKEIIDERTRERLVYEVRQKCRNIEDICISCGSLNVTLEHPLFVGGM 513
Query: 325 CQNCKNCFLECAYQYDDDGYQSYCTICCGGREVLMCGNNNCCRCFCVECVDLLVGPGAAQ 384
CQNCKNCFLECAYQYDDDGYQSYCTICCGGREVLMCGNNNCCRCFCVECVDLLVGPGAAQ
Sbjct: 514 CQNCKNCFLECAYQYDDDGYQSYCTICCGGREVLMCGNNNCCRCFCVECVDLLVGPGAAQ 573
Query: 385 AAIKEDPWNCYMCGHKGTYGLLRRREDWPSRLQMFFANNHDQEFDPPKVYPPVPAEKRKP 444
AAIKEDPWNCYMCGHKGTYGLLRRREDWPSRLQMFFANNHDQEFDPPKVYPPVPAEKRKP
Sbjct: 574 AAIKEDPWNCYMCGHKGTYGLLRRREDWPSRLQMFFANNHDQEFDPPKVYPPVPAEKRKP 633
Query: 445 IRVLSLFDGIATGLLVLKDLGIQVDRYIASEVCEDSITVGMVRHQGKIMYVGDVRSVTQK 504
IRVLSLFDGIATGLLVLKDLGIQVDRYIASEVCEDSITVGMVRHQGKIMYVGDVRSVTQK
Sbjct: 634 IRVLSLFDGIATGLLVLKDLGIQVDRYIASEVCEDSITVGMVRHQGKIMYVGDVRSVTQK 693
Query: 505 HIQEWGPFDLVIGGSPCNDLSIVNPARKGLYEGTGRLFFEFYRLLHDARPKEGDDRPFFW 564
HIQEWGPFDLVIGGSPCNDLSIVNPARKGLYEGTGRLFFEFYRLLHDARPKEGDDRPFFW
Sbjct: 694 HIQEWGPFDLVIGGSPCNDLSIVNPARKGLYEGTGRLFFEFYRLLHDARPKEGDDRPFFW 753
Query: 565 LFENVVAMGVSDKRDISRFLESNPVMIDAKEVSAAHRARYFWGNLPGMNRPLASTVNDKL 624
LFENVVAMGVSDKRDISRFLESNPVMIDAKEVSAAHRARYFWGNLPGMNRPLASTVNDKL
Sbjct: 754 LFENVVAMGVSDKRDISRFLESNPVMIDAKEVSAAHRARYFWGNLPGMNRPLASTVNDKL 813
Query: 625 ELQECLEHGRIAKFSKVRTITTRSNSIKQGKDQHFPVFMNEKEDILWCTEMERVFGFPVH 684
ELQECLEHGRIAKFSKVRTITTRSNSIKQGKDQHFPVFMNEKEDILWCTEMERVFGFPVH
Sbjct: 814 ELQECLEHGRIAKFSKVRTITTRSNSIKQGKDQHFPVFMNEKEDILWCTEMERVFGFPVH 873
Query: 685 YTDVSNMSRLARQRLLGRSWSVPVIRHLFAPLKEYFACV 723
YTDVSNMSRLARQRLLGRSWSVPVIRHLFAPLKEYFACV
Sbjct: 874 YTDVSNMSRLARQRLLGRSWSVPVIRHLFAPLKEYFACV 912
>gi|28559069 DNA cytosine methyltransferase 3 alpha isoform a [Homo
sapiens]
Length = 912
Score = 1471 bits (3809), Expect = 0.0
Identities = 699/699 (100%), Positives = 699/699 (100%)
Query: 25 AEKKAKVIAGMNAVEENQGPGESQKVEEASPPAVQQPTDPASPTVATTPEPVGSDAGDKN 84
AEKKAKVIAGMNAVEENQGPGESQKVEEASPPAVQQPTDPASPTVATTPEPVGSDAGDKN
Sbjct: 214 AEKKAKVIAGMNAVEENQGPGESQKVEEASPPAVQQPTDPASPTVATTPEPVGSDAGDKN 273
Query: 85 ATKAGDDEPEYEDGRGFGIGELVWGKLRGFSWWPGRIVSWWMTGRSRAAEGTRWVMWFGD 144
ATKAGDDEPEYEDGRGFGIGELVWGKLRGFSWWPGRIVSWWMTGRSRAAEGTRWVMWFGD
Sbjct: 274 ATKAGDDEPEYEDGRGFGIGELVWGKLRGFSWWPGRIVSWWMTGRSRAAEGTRWVMWFGD 333
Query: 145 GKFSVVCVEKLMPLSSFCSAFHQATYNKQPMYRKAIYEVLQVASSRAGKLFPVCHDSDES 204
GKFSVVCVEKLMPLSSFCSAFHQATYNKQPMYRKAIYEVLQVASSRAGKLFPVCHDSDES
Sbjct: 334 GKFSVVCVEKLMPLSSFCSAFHQATYNKQPMYRKAIYEVLQVASSRAGKLFPVCHDSDES 393
Query: 205 DTAKAVEVQNKPMIEWALGGFQPSGPKGLEPPEEEKNPYKEVYTDMWVEPEAAAYAPPPP 264
DTAKAVEVQNKPMIEWALGGFQPSGPKGLEPPEEEKNPYKEVYTDMWVEPEAAAYAPPPP
Sbjct: 394 DTAKAVEVQNKPMIEWALGGFQPSGPKGLEPPEEEKNPYKEVYTDMWVEPEAAAYAPPPP 453
Query: 265 AKKPRKSTAEKPKVKEIIDERTRERLVYEVRQKCRNIEDICISCGSLNVTLEHPLFVGGM 324
AKKPRKSTAEKPKVKEIIDERTRERLVYEVRQKCRNIEDICISCGSLNVTLEHPLFVGGM
Sbjct: 454 AKKPRKSTAEKPKVKEIIDERTRERLVYEVRQKCRNIEDICISCGSLNVTLEHPLFVGGM 513
Query: 325 CQNCKNCFLECAYQYDDDGYQSYCTICCGGREVLMCGNNNCCRCFCVECVDLLVGPGAAQ 384
CQNCKNCFLECAYQYDDDGYQSYCTICCGGREVLMCGNNNCCRCFCVECVDLLVGPGAAQ
Sbjct: 514 CQNCKNCFLECAYQYDDDGYQSYCTICCGGREVLMCGNNNCCRCFCVECVDLLVGPGAAQ 573
Query: 385 AAIKEDPWNCYMCGHKGTYGLLRRREDWPSRLQMFFANNHDQEFDPPKVYPPVPAEKRKP 444
AAIKEDPWNCYMCGHKGTYGLLRRREDWPSRLQMFFANNHDQEFDPPKVYPPVPAEKRKP
Sbjct: 574 AAIKEDPWNCYMCGHKGTYGLLRRREDWPSRLQMFFANNHDQEFDPPKVYPPVPAEKRKP 633
Query: 445 IRVLSLFDGIATGLLVLKDLGIQVDRYIASEVCEDSITVGMVRHQGKIMYVGDVRSVTQK 504
IRVLSLFDGIATGLLVLKDLGIQVDRYIASEVCEDSITVGMVRHQGKIMYVGDVRSVTQK
Sbjct: 634 IRVLSLFDGIATGLLVLKDLGIQVDRYIASEVCEDSITVGMVRHQGKIMYVGDVRSVTQK 693
Query: 505 HIQEWGPFDLVIGGSPCNDLSIVNPARKGLYEGTGRLFFEFYRLLHDARPKEGDDRPFFW 564
HIQEWGPFDLVIGGSPCNDLSIVNPARKGLYEGTGRLFFEFYRLLHDARPKEGDDRPFFW
Sbjct: 694 HIQEWGPFDLVIGGSPCNDLSIVNPARKGLYEGTGRLFFEFYRLLHDARPKEGDDRPFFW 753
Query: 565 LFENVVAMGVSDKRDISRFLESNPVMIDAKEVSAAHRARYFWGNLPGMNRPLASTVNDKL 624
LFENVVAMGVSDKRDISRFLESNPVMIDAKEVSAAHRARYFWGNLPGMNRPLASTVNDKL
Sbjct: 754 LFENVVAMGVSDKRDISRFLESNPVMIDAKEVSAAHRARYFWGNLPGMNRPLASTVNDKL 813
Query: 625 ELQECLEHGRIAKFSKVRTITTRSNSIKQGKDQHFPVFMNEKEDILWCTEMERVFGFPVH 684
ELQECLEHGRIAKFSKVRTITTRSNSIKQGKDQHFPVFMNEKEDILWCTEMERVFGFPVH
Sbjct: 814 ELQECLEHGRIAKFSKVRTITTRSNSIKQGKDQHFPVFMNEKEDILWCTEMERVFGFPVH 873
Query: 685 YTDVSNMSRLARQRLLGRSWSVPVIRHLFAPLKEYFACV 723
YTDVSNMSRLARQRLLGRSWSVPVIRHLFAPLKEYFACV
Sbjct: 874 YTDVSNMSRLARQRLLGRSWSVPVIRHLFAPLKEYFACV 912
>gi|28559065 DNA cytosine-5 methyltransferase 3 beta isoform 6 [Homo
sapiens]
Length = 845
Score = 830 bits (2145), Expect = 0.0
Identities = 395/646 (61%), Positives = 486/646 (75%), Gaps = 12/646 (1%)
Query: 77 GSDAGDKNATKAGDDEPEYEDGRGFGIGELVWGKLRGFSWWPGRIVSWWMTGRSRAAEGT 136
G ++ A D EY+DG+ FGIG+LVWGK++GFSWWP +VSW T + +A G
Sbjct: 211 GMESPQVEADSGDGDSSEYQDGKEFGIGDLVWGKIKGFSWWPAMVVSWKATSKRQAMSGM 270
Query: 137 RWVMWFGDGKFSVVCVEKLMPLSSFCSAFHQATYNKQPMYRKAIYEVLQVASSRAGKLFP 196
RWV WFGDGKFS V +KL+ L F F+ AT+NK YRKA+Y L+ A RAGK FP
Sbjct: 271 RWVQWFGDGKFSEVSADKLVALGLFSQHFNLATFNKLVSYRKAMYHALEKARVRAGKTFP 330
Query: 197 VCHDSDESDTAKAVEVQNKPMIEWALGGFQPSGPKGLEPPEEEKNPYKEVYTDMWVEPEA 256
S ++E Q KPM+EWA GGF+P+G +GL+P + P + +
Sbjct: 331 -------SSPGDSLEDQLKPMLEWAHGGFKPTGIEGLKPNNTQ--PENKTRRRTADDSAT 381
Query: 257 AAYAPPPPAKKPRKSTAEKPKVKEIIDERTRERLVYEVRQKCRNIEDICISCGSLNVTLE 316
+ Y P P K K + E +++RE++ +V ++ED C+SCG N
Sbjct: 382 SDYCPAPKRLKTNCYNNGKDRGDE---DQSREQMASDVANNKSSLEDGCLSCGRKNPVSF 438
Query: 317 HPLFVGGMCQNCKNCFLECAYQYDDDGYQSYCTICCGGREVLMCGNNNCCRCFCVECVDL 376
HPLF GG+CQ C++ FLE Y YDDDGYQSYCT+CC GRE+L+C N +CCRCFCVEC+++
Sbjct: 439 HPLFEGGLCQTCRDRFLELFYMYDDDGYQSYCTVCCEGRELLLCSNTSCCRCFCVECLEV 498
Query: 377 LVGPGAAQAAIKEDPWNCYMCGHKGTYGLLRRREDWPSRLQMFFANNHDQEFDPPKVYPP 436
LVG G A A ++PW+CYMC + +G+LRRR+DW RLQ FF ++ E++ PK+YP
Sbjct: 499 LVGTGTAAEAKLQEPWSCYMCLPQRCHGVLRRRKDWNVRLQAFFTSDTGLEYEAPKLYPA 558
Query: 437 VPAEKRKPIRVLSLFDGIATGLLVLKDLGIQVDRYIASEVCEDSITVGMVRHQGKIMYVG 496
+PA +R+PIRVLSLFDGIATG LVLK+LGI+V +Y+ASEVCE+SI VG V+H+G I YV
Sbjct: 559 IPAARRRPIRVLSLFDGIATGYLVLKELGIKVGKYVASEVCEESIAVGTVKHEGNIKYVN 618
Query: 497 DVRSVTQKHIQEWGPFDLVIGGSPCNDLSIVNPARKGLYEGTGRLFFEFYRLLHDARPKE 556
DVR++T+K+I+EWGPFDLVIGGSPCNDLS VNPARKGLYEGTGRLFFEFY LL+ +RPKE
Sbjct: 619 DVRNITKKNIEEWGPFDLVIGGSPCNDLSNVNPARKGLYEGTGRLFFEFYHLLNYSRPKE 678
Query: 557 GDDRPFFWLFENVVAMGVSDKRDISRFLESNPVMIDAKEVSAAHRARYFWGNLPGMNRPL 616
GDDRPFFW+FENVVAM V DKRDISRFLE NPVMIDA +VSAAHRARYFWGNLPGMNRP+
Sbjct: 679 GDDRPFFWMFENVVAMKVGDKRDISRFLECNPVMIDAIKVSAAHRARYFWGNLPGMNRPV 738
Query: 617 ASTVNDKLELQECLEHGRIAKFSKVRTITTRSNSIKQGKDQHFPVFMNEKEDILWCTEME 676
++ NDKLELQ+CLE+ RIAK KV+TITT+SNSIKQGK+Q FPV MN KED+LWCTE+E
Sbjct: 739 IASKNDKLELQDCLEYNRIAKLKKVQTITTKSNSIKQGKNQLFPVVMNGKEDVLWCTELE 798
Query: 677 RVFGFPVHYTDVSNMSRLARQRLLGRSWSVPVIRHLFAPLKEYFAC 722
R+FGFPVHYTDVSNM R ARQ+LLGRSWSVPVIRHLFAPLK+YFAC
Sbjct: 799 RIFGFPVHYTDVSNMGRGARQKLLGRSWSVPVIRHLFAPLKDYFAC 844
>gi|28559061 DNA cytosine-5 methyltransferase 3 beta isoform 2 [Homo
sapiens]
Length = 833
Score = 830 bits (2145), Expect = 0.0
Identities = 395/646 (61%), Positives = 486/646 (75%), Gaps = 12/646 (1%)
Query: 77 GSDAGDKNATKAGDDEPEYEDGRGFGIGELVWGKLRGFSWWPGRIVSWWMTGRSRAAEGT 136
G ++ A D EY+DG+ FGIG+LVWGK++GFSWWP +VSW T + +A G
Sbjct: 199 GMESPQVEADSGDGDSSEYQDGKEFGIGDLVWGKIKGFSWWPAMVVSWKATSKRQAMSGM 258
Query: 137 RWVMWFGDGKFSVVCVEKLMPLSSFCSAFHQATYNKQPMYRKAIYEVLQVASSRAGKLFP 196
RWV WFGDGKFS V +KL+ L F F+ AT+NK YRKA+Y L+ A RAGK FP
Sbjct: 259 RWVQWFGDGKFSEVSADKLVALGLFSQHFNLATFNKLVSYRKAMYHALEKARVRAGKTFP 318
Query: 197 VCHDSDESDTAKAVEVQNKPMIEWALGGFQPSGPKGLEPPEEEKNPYKEVYTDMWVEPEA 256
S ++E Q KPM+EWA GGF+P+G +GL+P + P + +
Sbjct: 319 -------SSPGDSLEDQLKPMLEWAHGGFKPTGIEGLKPNNTQ--PENKTRRRTADDSAT 369
Query: 257 AAYAPPPPAKKPRKSTAEKPKVKEIIDERTRERLVYEVRQKCRNIEDICISCGSLNVTLE 316
+ Y P P K K + E +++RE++ +V ++ED C+SCG N
Sbjct: 370 SDYCPAPKRLKTNCYNNGKDRGDE---DQSREQMASDVANNKSSLEDGCLSCGRKNPVSF 426
Query: 317 HPLFVGGMCQNCKNCFLECAYQYDDDGYQSYCTICCGGREVLMCGNNNCCRCFCVECVDL 376
HPLF GG+CQ C++ FLE Y YDDDGYQSYCT+CC GRE+L+C N +CCRCFCVEC+++
Sbjct: 427 HPLFEGGLCQTCRDRFLELFYMYDDDGYQSYCTVCCEGRELLLCSNTSCCRCFCVECLEV 486
Query: 377 LVGPGAAQAAIKEDPWNCYMCGHKGTYGLLRRREDWPSRLQMFFANNHDQEFDPPKVYPP 436
LVG G A A ++PW+CYMC + +G+LRRR+DW RLQ FF ++ E++ PK+YP
Sbjct: 487 LVGTGTAAEAKLQEPWSCYMCLPQRCHGVLRRRKDWNVRLQAFFTSDTGLEYEAPKLYPA 546
Query: 437 VPAEKRKPIRVLSLFDGIATGLLVLKDLGIQVDRYIASEVCEDSITVGMVRHQGKIMYVG 496
+PA +R+PIRVLSLFDGIATG LVLK+LGI+V +Y+ASEVCE+SI VG V+H+G I YV
Sbjct: 547 IPAARRRPIRVLSLFDGIATGYLVLKELGIKVGKYVASEVCEESIAVGTVKHEGNIKYVN 606
Query: 497 DVRSVTQKHIQEWGPFDLVIGGSPCNDLSIVNPARKGLYEGTGRLFFEFYRLLHDARPKE 556
DVR++T+K+I+EWGPFDLVIGGSPCNDLS VNPARKGLYEGTGRLFFEFY LL+ +RPKE
Sbjct: 607 DVRNITKKNIEEWGPFDLVIGGSPCNDLSNVNPARKGLYEGTGRLFFEFYHLLNYSRPKE 666
Query: 557 GDDRPFFWLFENVVAMGVSDKRDISRFLESNPVMIDAKEVSAAHRARYFWGNLPGMNRPL 616
GDDRPFFW+FENVVAM V DKRDISRFLE NPVMIDA +VSAAHRARYFWGNLPGMNRP+
Sbjct: 667 GDDRPFFWMFENVVAMKVGDKRDISRFLECNPVMIDAIKVSAAHRARYFWGNLPGMNRPV 726
Query: 617 ASTVNDKLELQECLEHGRIAKFSKVRTITTRSNSIKQGKDQHFPVFMNEKEDILWCTEME 676
++ NDKLELQ+CLE+ RIAK KV+TITT+SNSIKQGK+Q FPV MN KED+LWCTE+E
Sbjct: 727 IASKNDKLELQDCLEYNRIAKLKKVQTITTKSNSIKQGKNQLFPVVMNGKEDVLWCTELE 786
Query: 677 RVFGFPVHYTDVSNMSRLARQRLLGRSWSVPVIRHLFAPLKEYFAC 722
R+FGFPVHYTDVSNM R ARQ+LLGRSWSVPVIRHLFAPLK+YFAC
Sbjct: 787 RIFGFPVHYTDVSNMGRGARQKLLGRSWSVPVIRHLFAPLKDYFAC 832
>gi|5901940 DNA cytosine-5 methyltransferase 3 beta isoform 1 [Homo
sapiens]
Length = 853
Score = 825 bits (2131), Expect = 0.0
Identities = 397/664 (59%), Positives = 487/664 (73%), Gaps = 28/664 (4%)
Query: 77 GSDAGDKNATKAGDDEPEYEDGRGFGIGELVWGKLRGFSWWPGRIVSWWMTGRSRAAEGT 136
G ++ A D EY+DG+ FGIG+LVWGK++GFSWWP +VSW T + +A G
Sbjct: 199 GMESPQVEADSGDGDSSEYQDGKEFGIGDLVWGKIKGFSWWPAMVVSWKATSKRQAMSGM 258
Query: 137 RWVMWFGDGKFSVVCVEKLMPLSSFCSAFHQATYNKQPMYRKAIYEVLQVASSRAGKLFP 196
RWV WFGDGKFS V +KL+ L F F+ AT+NK YRKA+Y L+ A RAGK FP
Sbjct: 259 RWVQWFGDGKFSEVSADKLVALGLFSQHFNLATFNKLVSYRKAMYHALEKARVRAGKTFP 318
Query: 197 VCHDSDESDTAKAVEVQNKPMIEWALGGFQPSGPKGLEPPEE-----------------E 239
S ++E Q KPM+EWA GGF+P+G +GL+P E
Sbjct: 319 -------SSPGDSLEDQLKPMLEWAHGGFKPTGIEGLKPNNTQPVVNKSKVRRAGSRKLE 371
Query: 240 KNPYKEVYTDMWVEPEAAA-YAPPPPAKKPRKSTAEKPKVKEIIDERTRERLVYEVRQKC 298
Y+ + A + Y P P K K + E +++RE++ +V
Sbjct: 372 SRKYENKTRRRTADDSATSDYCPAPKRLKTNCYNNGKDRGDE---DQSREQMASDVANNK 428
Query: 299 RNIEDICISCGSLNVTLEHPLFVGGMCQNCKNCFLECAYQYDDDGYQSYCTICCGGREVL 358
++ED C+SCG N HPLF GG+CQ C++ FLE Y YDDDGYQSYCT+CC GRE+L
Sbjct: 429 SSLEDGCLSCGRKNPVSFHPLFEGGLCQTCRDRFLELFYMYDDDGYQSYCTVCCEGRELL 488
Query: 359 MCGNNNCCRCFCVECVDLLVGPGAAQAAIKEDPWNCYMCGHKGTYGLLRRREDWPSRLQM 418
+C N +CCRCFCVEC+++LVG G A A ++PW+CYMC + +G+LRRR+DW RLQ
Sbjct: 489 LCSNTSCCRCFCVECLEVLVGTGTAAEAKLQEPWSCYMCLPQRCHGVLRRRKDWNVRLQA 548
Query: 419 FFANNHDQEFDPPKVYPPVPAEKRKPIRVLSLFDGIATGLLVLKDLGIQVDRYIASEVCE 478
FF ++ E++ PK+YP +PA +R+PIRVLSLFDGIATG LVLK+LGI+V +Y+ASEVCE
Sbjct: 549 FFTSDTGLEYEAPKLYPAIPAARRRPIRVLSLFDGIATGYLVLKELGIKVGKYVASEVCE 608
Query: 479 DSITVGMVRHQGKIMYVGDVRSVTQKHIQEWGPFDLVIGGSPCNDLSIVNPARKGLYEGT 538
+SI VG V+H+G I YV DVR++T+K+I+EWGPFDLVIGGSPCNDLS VNPARKGLYEGT
Sbjct: 609 ESIAVGTVKHEGNIKYVNDVRNITKKNIEEWGPFDLVIGGSPCNDLSNVNPARKGLYEGT 668
Query: 539 GRLFFEFYRLLHDARPKEGDDRPFFWLFENVVAMGVSDKRDISRFLESNPVMIDAKEVSA 598
GRLFFEFY LL+ +RPKEGDDRPFFW+FENVVAM V DKRDISRFLE NPVMIDA +VSA
Sbjct: 669 GRLFFEFYHLLNYSRPKEGDDRPFFWMFENVVAMKVGDKRDISRFLECNPVMIDAIKVSA 728
Query: 599 AHRARYFWGNLPGMNRPLASTVNDKLELQECLEHGRIAKFSKVRTITTRSNSIKQGKDQH 658
AHRARYFWGNLPGMNRP+ ++ NDKLELQ+CLE+ RIAK KV+TITT+SNSIKQGK+Q
Sbjct: 729 AHRARYFWGNLPGMNRPVIASKNDKLELQDCLEYNRIAKLKKVQTITTKSNSIKQGKNQL 788
Query: 659 FPVFMNEKEDILWCTEMERVFGFPVHYTDVSNMSRLARQRLLGRSWSVPVIRHLFAPLKE 718
FPV MN KED+LWCTE+ER+FGFPVHYTDVSNM R ARQ+LLGRSWSVPVIRHLFAPLK+
Sbjct: 789 FPVVMNGKEDVLWCTELERIFGFPVHYTDVSNMGRGARQKLLGRSWSVPVIRHLFAPLKD 848
Query: 719 YFAC 722
YFAC
Sbjct: 849 YFAC 852
>gi|28559063 DNA cytosine-5 methyltransferase 3 beta isoform 3 [Homo
sapiens]
Length = 770
Score = 650 bits (1678), Expect = 0.0
Identities = 310/538 (57%), Positives = 388/538 (72%), Gaps = 12/538 (2%)
Query: 77 GSDAGDKNATKAGDDEPEYEDGRGFGIGELVWGKLRGFSWWPGRIVSWWMTGRSRAAEGT 136
G ++ A D EY+DG+ FGIG+LVWGK++GFSWWP +VSW T + +A G
Sbjct: 199 GMESPQVEADSGDGDSSEYQDGKEFGIGDLVWGKIKGFSWWPAMVVSWKATSKRQAMSGM 258
Query: 137 RWVMWFGDGKFSVVCVEKLMPLSSFCSAFHQATYNKQPMYRKAIYEVLQVASSRAGKLFP 196
RWV WFGDGKFS V +KL+ L F F+ AT+NK YRKA+Y L+ A RAGK FP
Sbjct: 259 RWVQWFGDGKFSEVSADKLVALGLFSQHFNLATFNKLVSYRKAMYHALEKARVRAGKTFP 318
Query: 197 VCHDSDESDTAKAVEVQNKPMIEWALGGFQPSGPKGLEPPEEEKNPYKEVYTDMWVEPEA 256
S ++E Q KPM+EWA GGF+P+G +GL+P + P + +
Sbjct: 319 -------SSPGDSLEDQLKPMLEWAHGGFKPTGIEGLKPNNTQ--PENKTRRRTADDSAT 369
Query: 257 AAYAPPPPAKKPRKSTAEKPKVKEIIDERTRERLVYEVRQKCRNIEDICISCGSLNVTLE 316
+ Y P P K K + E +++RE++ +V ++ED C+SCG N
Sbjct: 370 SDYCPAPKRLKTNCYNNGKDRGDE---DQSREQMASDVANNKSSLEDGCLSCGRKNPVSF 426
Query: 317 HPLFVGGMCQNCKNCFLECAYQYDDDGYQSYCTICCGGREVLMCGNNNCCRCFCVECVDL 376
HPLF GG+CQ C++ FLE Y YDDDGYQSYCT+CC GRE+L+C N +CCRCFCVEC+++
Sbjct: 427 HPLFEGGLCQTCRDRFLELFYMYDDDGYQSYCTVCCEGRELLLCSNTSCCRCFCVECLEV 486
Query: 377 LVGPGAAQAAIKEDPWNCYMCGHKGTYGLLRRREDWPSRLQMFFANNHDQEFDPPKVYPP 436
LVG G A A ++PW+CYMC + +G+LRRR+DW RLQ FF ++ E++ PK+YP
Sbjct: 487 LVGTGTAAEAKLQEPWSCYMCLPQRCHGVLRRRKDWNVRLQAFFTSDTGLEYEAPKLYPA 546
Query: 437 VPAEKRKPIRVLSLFDGIATGLLVLKDLGIQVDRYIASEVCEDSITVGMVRHQGKIMYVG 496
+PA +R+PIRVLSLFDGIATG LVLK+LGI+V +Y+ASEVCE+SI VG V+H+G I YV
Sbjct: 547 IPAARRRPIRVLSLFDGIATGYLVLKELGIKVGKYVASEVCEESIAVGTVKHEGNIKYVN 606
Query: 497 DVRSVTQKHIQEWGPFDLVIGGSPCNDLSIVNPARKGLYEGTGRLFFEFYRLLHDARPKE 556
DVR++T+K+I+EWGPFDLVIGGSPCNDLS VNPARKGLYEGTGRLFFEFY LL+ +RPKE
Sbjct: 607 DVRNITKKNIEEWGPFDLVIGGSPCNDLSNVNPARKGLYEGTGRLFFEFYHLLNYSRPKE 666
Query: 557 GDDRPFFWLFENVVAMGVSDKRDISRFLESNPVMIDAKEVSAAHRARYFWGNLPGMNR 614
GDDRPFFW+FENVVAM V DKRDISRFLE NPVMIDA +VSAAHRARYFWGNLPGMNR
Sbjct: 667 GDDRPFFWMFENVVAMKVGDKRDISRFLECNPVMIDAIKVSAAHRARYFWGNLPGMNR 724
>gi|28872780 cytosine-5-methyltransferase 3-like protein isoform 2
[Homo sapiens]
Length = 386
Score = 253 bits (646), Expect = 4e-67
Identities = 137/341 (40%), Positives = 184/341 (53%), Gaps = 31/341 (9%)
Query: 287 RERLVYEVRQKCRNIEDICISCGSLNVTLEHPLFVGGMCQNCKNCFLECAYQYDDDGYQS 346
R+ + YEV+ RNIEDICI CGSL V +HPLF GG+C CK+ FL+ + YDDDGYQS
Sbjct: 35 RDLIAYEVKANQRNIEDICICCGSLQVHTQHPLFEGGICAPCKDKFLDALFLYDDDGYQS 94
Query: 347 YCTICCGGREVLMCGNNNCCRCFCVECVDLLVGPGAAQAAIKEDPWNCYMCGHKGTYGLL 406
YC+ICC G +L+CGN +C RC+C ECVD LVGPG + W CY+C GLL
Sbjct: 95 YCSICCSGETLLICGNPDCTRCYCFECVDSLVGPGTSGKVHAMSNWVCYLCLPSSRSGLL 154
Query: 407 RRREDWPSRLQMFFANNHDQEFDPPKVYPPVPAEKRKPIRVLSLFDGIATGLLVLKDLGI 466
+RR W S+L+ F+ + +P +++ VP +R+P+RVLSLF+ I L L L
Sbjct: 155 QRRRKWRSQLKAFYDRESE---NPLEMFETVPVWRRQPVRVLSLFEDIKKELTSLGFLES 211
Query: 467 QVDRYIASEVCEDSITVGMVRHQGKIMYVGDVRSVTQKHIQEWGPFDLVIGGSPCNDLSI 526
D G++ +V DV +K ++EWGPFDLV G +P
Sbjct: 212 GSD-------------------PGQLKHVVDVTDTVRKDVEEWGPFDLVYGATP------ 246
Query: 527 VNPARKGLYEGTGRLFFEFYRLLHDARPKEGDDRPFFWLFENVVAMGVSDKRDISRFLES 586
P F+F+RLL ARPK G RPFFW+F + + + D SRFLE
Sbjct: 247 --PLGHTCDRPPSWYLFQFHRLLQYARPKPGSPRPFFWMFVDNLVLNKEDLDVASRFLEM 304
Query: 587 NPVMIDAKEVSAAHRARYFWGNLPGM-NRPLASTVNDKLEL 626
PV I + A W N+P + +R A ++L L
Sbjct: 305 EPVTIPDVHGGSLQNAVRVWSNIPAIRSRHWALVSEEELSL 345
>gi|28872778 cytosine-5-methyltransferase 3-like protein isoform 1
[Homo sapiens]
Length = 387
Score = 253 bits (645), Expect = 6e-67
Identities = 133/326 (40%), Positives = 177/326 (54%), Gaps = 30/326 (9%)
Query: 287 RERLVYEVRQKCRNIEDICISCGSLNVTLEHPLFVGGMCQNCKNCFLECAYQYDDDGYQS 346
R+ + YEV+ RNIEDICI CGSL V +HPLF GG+C CK+ FL+ + YDDDGYQS
Sbjct: 35 RDLIAYEVKANQRNIEDICICCGSLQVHTQHPLFEGGICAPCKDKFLDALFLYDDDGYQS 94
Query: 347 YCTICCGGREVLMCGNNNCCRCFCVECVDLLVGPGAAQAAIKEDPWNCYMCGHKGTYGLL 406
YC+ICC G +L+CGN +C RC+C ECVD LVGPG + W CY+C GLL
Sbjct: 95 YCSICCSGETLLICGNPDCTRCYCFECVDSLVGPGTSGKVHAMSNWVCYLCLPSSRSGLL 154
Query: 407 RRREDWPSRLQMFFANNHDQEFDPPKVYPPVPAEKRKPIRVLSLFDGIATGLLVLKDLGI 466
+RR W S+L+ F+ + +P +++ VP +R+P+RVLSLF+ I L L L
Sbjct: 155 QRRRKWRSQLKAFYDRESE---NPLEMFETVPVWRRQPVRVLSLFEDIKKELTSLGFLES 211
Query: 467 QVDRYIASEVCEDSITVGMVRHQGKIMYVGDVRSVTQKHIQEWGPFDLVIGGSPCNDLSI 526
D G++ +V DV +K ++EWGPFDLV G +P
Sbjct: 212 GSD-------------------PGQLKHVVDVTDTVRKDVEEWGPFDLVYGATP------ 246
Query: 527 VNPARKGLYEGTGRLFFEFYRLLHDARPKEGDDRPFFWLFENVVAMGVSDKRDISRFLES 586
P F+F+RLL ARPK G RPFFW+F + + + D SRFLE
Sbjct: 247 --PLGHTCDRPPSWYLFQFHRLLQYARPKPGSPRPFFWMFVDNLVLNKEDLDVASRFLEM 304
Query: 587 NPVMIDAKEVSAAHRARYFWGNLPGM 612
PV I + A W N+P +
Sbjct: 305 EPVTIPDVHGGSLQNAVRVWSNIPAI 330
>gi|148839376 PWWP domain containing 2 isoform 1 [Homo sapiens]
Length = 590
Score = 65.9 bits (159), Expect = 1e-10
Identities = 35/94 (37%), Positives = 47/94 (50%), Gaps = 4/94 (4%)
Query: 96 EDGRGFGIGELVWGKLRGFSWWPGRIVSWWMTGRSRAAEGTR--WVMWFGDGKFSVVCVE 153
EDGR +G++VWGK+ GF WWP R++ + + R V WFG S + +
Sbjct: 483 EDGRTVAVGDIVWGKIHGFPWWPARVLDISLGQKEDGEPSWREAKVSWFGSPTTSFLSIS 542
Query: 154 KLMPLSSFCSAFHQATYNKQPMYRKAIYEVLQVA 187
KL P S F + K+ MYRKAI E A
Sbjct: 543 KLSPFSEFFKL--RFNRKKKGMYRKAITEAANAA 574
>gi|195963316 PWWP domain containing 2A isoform b [Homo sapiens]
Length = 755
Score = 57.4 bits (137), Expect = 5e-08
Identities = 31/94 (32%), Positives = 51/94 (54%), Gaps = 6/94 (6%)
Query: 97 DGRGFGIGELVWGKLRGFSWWPGRIVSWWMTGRSRA--AEGTRWVMWFGDGKFSVVCVEK 154
DGR +G++VW K+ GF WWP RI++ ++ + + WFG S + + +
Sbjct: 649 DGRTICVGDIVWAKIYGFPWWPARILTITVSRKDNGLLVRQEARISWFGSPTTSFLALSQ 708
Query: 155 LMP-LSSFCSAFHQATYNKQPMYRKAIYEVLQVA 187
L P L +F S F++ ++ +YRKAI E + A
Sbjct: 709 LSPFLENFQSRFNK---KRKGLYRKAITEAAKAA 739
>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
Length = 2492
Score = 45.8 bits (107), Expect = 1e-04
Identities = 38/168 (22%), Positives = 59/168 (35%), Gaps = 11/168 (6%)
Query: 237 EEEKNPYKEVYTDMWVEPEAAAYAPPPPAKKPRKSTAEKPKVKEIIDERTRERLVYEVRQ 296
E+ N E M P+ P P K + P+ + +T E L
Sbjct: 105 EDASNENSENDITMQSLPKGTVIVQPEPVLNEDKDDFKGPEFRSRSKMKT-ENLKKRGED 163
Query: 297 KCRNIEDICISCGSL------NVTLEHPLFVGGMCQNCKNCFLECAYQYDDDGYQSYCTI 350
I C +CG + HP +C+NC ++ D DG C
Sbjct: 164 GLHGIVS-CTACGQQVNHFQKDSIYRHPSLQVLICKNCFKYYMSDDISRDSDGMDEQCRW 222
Query: 351 CCGGREVLMCGNNNCCRCFCVECVDLLVGPGAAQAAIKE-DPWNCYMC 397
C G ++ C + C FC +C+ +G + E + W CY+C
Sbjct: 223 CAEGGNLICC--DFCHNAFCKKCILRNLGRKELSTIMDENNQWYCYIC 268
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 45.4 bits (106), Expect = 2e-04
Identities = 36/150 (24%), Positives = 58/150 (38%), Gaps = 16/150 (10%)
Query: 262 PPPAKKPRKSTAEKPKVKEIIDE-RTRERLVYEVRQKCRNIED------ICISCGSL--- 311
P K +S EKP E ++E + E ++ + ED C +CG
Sbjct: 83 PSIVTKYVESDDEKPLDDETVNEDASNENSENDITMQSLPKEDGLHGIVSCTACGQQVNH 142
Query: 312 ---NVTLEHPLFVGGMCQNCKNCFLECAYQYDDDGYQSYCTICCGGREVLMCGNNNCCRC 368
+ HP +C+NC ++ D DG C C G ++ C + C
Sbjct: 143 FQKDSIYRHPSLQVLICKNCFKYYMSDDISRDSDGMDEQCRWCAEGGNLICC--DFCHNA 200
Query: 369 FCVECVDLLVGPGAAQAAIKE-DPWNCYMC 397
FC +C+ +G + E + W CY+C
Sbjct: 201 FCKKCILRNLGRKELSTIMDENNQWYCYIC 230
>gi|110681712 hepatoma derived growth factor-like 1 [Homo sapiens]
Length = 251
Score = 42.0 bits (97), Expect = 0.002
Identities = 43/181 (23%), Positives = 71/181 (39%), Gaps = 18/181 (9%)
Query: 104 GELVWGKLRGFSWWPGRIVSWWMTGRSRAAEGTRWVMWFGDGKFSVVCVEKLMPLSSFCS 163
G+LV+ KL+G++ WP RI R + V +FG + + + ++L P
Sbjct: 12 GDLVFAKLKGYAHWPARIEHMTQPNRYQ-------VFFFGTHETAFLSPKRLFPYKECKE 64
Query: 164 AFHQATYNKQPMYRKAIYEVLQVASSRAGKLFPVCHDSDESD----TAKAVEVQNKPMIE 219
F + NK+ + ++E+ + +A P+ + D +A E
Sbjct: 65 KFGKP--NKRRGFSAGLWEIENNPTVQASDC-PLASEKGSGDGPWPEPEAAEGDEDKPTH 121
Query: 220 WALGGFQPSGPKGLEPPEEEKNPYKEVYTDMWVEPEAAAYAPPPPAKKPRKSTAEKPKVK 279
GG + P +P EEEK P K D P A P A ++ AE +
Sbjct: 122 AGGGGDELGKPDDDKPTEEEKGPLKRSAGD----PPEDAPKRPKEAAPDQEEEAEAERAA 177
Query: 280 E 280
E
Sbjct: 178 E 178
>gi|40556376 cytokine-like nuclear factor n-pac [Homo sapiens]
Length = 553
Score = 41.2 bits (95), Expect = 0.003
Identities = 30/115 (26%), Positives = 55/115 (47%), Gaps = 3/115 (2%)
Query: 103 IGELVWGKLRGFSWWPGRIVSWWMTGRSRAAEGTRWVMWFGDGKFSVVCVEKLMPLSSFC 162
+G+LVWGKL + WPG+IV+ + + +V +FG + + VE+L P +
Sbjct: 8 LGDLVWGKLGRYPPWPGKIVNPPKDLKKPRGKKCFFVKFFGTEDHAWIKVEQLKPYHAHK 67
Query: 163 SAFHQATYNKQPMYRKAIYEVLQVASSRAGKLFPVCHD-SDESDTAKAVEVQNKP 216
NK +++A+ V + GK H+ SD+ + + E +++P
Sbjct: 68 E--EMIKINKGKRFQQAVDAVEEFLRRAKGKDQTSSHNSSDDKNRRNSSEERSRP 120
>gi|38202209 methyl-CpG binding domain protein 5 [Homo sapiens]
Length = 1494
Score = 39.3 bits (90), Expect = 0.013
Identities = 26/97 (26%), Positives = 45/97 (46%), Gaps = 7/97 (7%)
Query: 33 AGMNAVEENQGPGESQKVEEAS-PPAVQQPTDPASPTV-ATTPEP-----VGSDAGDKNA 85
A + V E Q P S +E + + D + +V P P + S+ +N
Sbjct: 1308 AKQDLVLEEQSPSSSNSLENSLVKDYIHYNGDFNAKSVNGCVPSPSDAKSISSEDDLRNP 1367
Query: 86 TKAGDDEPEYEDGRGFGIGELVWGKLRGFSWWPGRIV 122
+E + R F +G+LVWG+++G + WPG++V
Sbjct: 1368 DSPSSNELIHYRPRTFNVGDLVWGQIKGLTSWPGKLV 1404
>gi|24308089 chromodomain helicase DNA binding protein 5 [Homo
sapiens]
Length = 1954
Score = 37.7 bits (86), Expect = 0.038
Identities = 22/66 (33%), Positives = 33/66 (50%), Gaps = 12/66 (18%)
Query: 340 DDDGY----QSYCTICCGGREVLMCGNNNCCRCFCVECVDLLVGPGAAQAAIKEDPWNCY 395
D DGY Q YC +C G E+++C + C R + + C+D P +A E W+C
Sbjct: 334 DGDGYETDHQDYCEVCQQGGEIILC--DTCPRAYHLVCLD----PELEKA--PEGKWSCP 385
Query: 396 MCGHKG 401
C +G
Sbjct: 386 HCEKEG 391
>gi|13699811 WHSC1L1 protein isoform long [Homo sapiens]
Length = 1437
Score = 37.7 bits (86), Expect = 0.038
Identities = 22/80 (27%), Positives = 35/80 (43%), Gaps = 3/80 (3%)
Query: 46 ESQKVEEASPPAVQQPTDPASPTVATTP--EPVGSDAGDKNATKAGDDEPEYEDGRGFGI 103
+S K+ + P +P + TV+ P EPV + + E G F +
Sbjct: 212 KSHKIPKLEPEEQNRPNERVD-TVSEKPREEPVLKEEAPVQPILSSVPTTEVSTGVKFQV 270
Query: 104 GELVWGKLRGFSWWPGRIVS 123
G+LVW K+ + WWP + S
Sbjct: 271 GDLVWSKVGTYPWWPCMVSS 290
Score = 31.2 bits (69), Expect = 3.5
Identities = 16/55 (29%), Positives = 27/55 (49%), Gaps = 5/55 (9%)
Query: 344 YQSYCTICCGGREVLMCGNNNCCRCFCVECVDLLVGPGAAQAAIKEDPWN-CYMC 397
++ YC C G E++MC +C + + + C++L P E PW+ C C
Sbjct: 1320 HEDYCFQCGDGGELVMCDKKDCPKAYHLLCLNLTQPPYGKW----ECPWHQCDEC 1370
>gi|13699813 WHSC1L1 protein isoform short [Homo sapiens]
Length = 645
Score = 37.7 bits (86), Expect = 0.038
Identities = 22/80 (27%), Positives = 35/80 (43%), Gaps = 3/80 (3%)
Query: 46 ESQKVEEASPPAVQQPTDPASPTVATTP--EPVGSDAGDKNATKAGDDEPEYEDGRGFGI 103
+S K+ + P +P + TV+ P EPV + + E G F +
Sbjct: 212 KSHKIPKLEPEEQNRPNERVD-TVSEKPREEPVLKEEAPVQPILSSVPTTEVSTGVKFQV 270
Query: 104 GELVWGKLRGFSWWPGRIVS 123
G+LVW K+ + WWP + S
Sbjct: 271 GDLVWSKVGTYPWWPCMVSS 290
>gi|51599156 chromodomain helicase DNA binding protein 4 [Homo
sapiens]
Length = 1912
Score = 36.2 bits (82), Expect = 0.11
Identities = 21/64 (32%), Positives = 32/64 (50%), Gaps = 12/64 (18%)
Query: 342 DGY----QSYCTICCGGREVLMCGNNNCCRCFCVECVDLLVGPGAAQAAIKEDPWNCYMC 397
DGY Q YC +C G E+++C + C R + + C+D P +A E W+C C
Sbjct: 363 DGYETDHQDYCEVCQQGGEIILC--DTCPRAYHMVCLD----PDMEKA--PEGKWSCPHC 414
Query: 398 GHKG 401
+G
Sbjct: 415 EKEG 418
>gi|52630326 chromodomain helicase DNA binding protein 3 isoform 1
[Homo sapiens]
Length = 2000
Score = 36.2 bits (82), Expect = 0.11
Identities = 22/74 (29%), Positives = 35/74 (47%), Gaps = 12/74 (16%)
Query: 342 DGY----QSYCTICCGGREVLMCGNNNCCRCFCVECVDLLVGPGAAQAAIKEDPWNCYMC 397
DGY Q YC +C G E+++C + C R + + C+D P +A E W+C C
Sbjct: 372 DGYETDHQDYCEVCQQGGEIILC--DTCPRAYHLVCLD----PELDRA--PEGKWSCPHC 423
Query: 398 GHKGTYGLLRRRED 411
+G + E+
Sbjct: 424 EKEGVQWEAKEEEE 437
Score = 30.0 bits (66), Expect = 7.9
Identities = 23/103 (22%), Positives = 37/103 (35%), Gaps = 8/103 (7%)
Query: 340 DDDGYQSYCTICCGGREVLMCGNNNCCRCFCVECVDLLVGPGAAQAAIKEDPWNCYMCGH 399
++D + YC +C G E+L C + C + + C++ I W C C
Sbjct: 451 EEDDHMEYCRVCKDGGELLCC--DACISSYHIHCLN------PPLPDIPNGEWLCPRCTC 502
Query: 400 KGTYGLLRRREDWPSRLQMFFANNHDQEFDPPKVYPPVPAEKR 442
G +++ W Q P V PP P + R
Sbjct: 503 PVLKGRVQKILHWRWGEPPVAVPAPQQADGNPDVPPPRPLQGR 545
>gi|52630322 chromodomain helicase DNA binding protein 3 isoform 2
[Homo sapiens]
Length = 1966
Score = 36.2 bits (82), Expect = 0.11
Identities = 22/74 (29%), Positives = 35/74 (47%), Gaps = 12/74 (16%)
Query: 342 DGY----QSYCTICCGGREVLMCGNNNCCRCFCVECVDLLVGPGAAQAAIKEDPWNCYMC 397
DGY Q YC +C G E+++C + C R + + C+D P +A E W+C C
Sbjct: 372 DGYETDHQDYCEVCQQGGEIILC--DTCPRAYHLVCLD----PELDRA--PEGKWSCPHC 423
Query: 398 GHKGTYGLLRRRED 411
+G + E+
Sbjct: 424 EKEGVQWEAKEEEE 437
Score = 30.0 bits (66), Expect = 7.9
Identities = 23/103 (22%), Positives = 37/103 (35%), Gaps = 8/103 (7%)
Query: 340 DDDGYQSYCTICCGGREVLMCGNNNCCRCFCVECVDLLVGPGAAQAAIKEDPWNCYMCGH 399
++D + YC +C G E+L C + C + + C++ I W C C
Sbjct: 451 EEDDHMEYCRVCKDGGELLCC--DACISSYHIHCLN------PPLPDIPNGEWLCPRCTC 502
Query: 400 KGTYGLLRRREDWPSRLQMFFANNHDQEFDPPKVYPPVPAEKR 442
G +++ W Q P V PP P + R
Sbjct: 503 PVLKGRVQKILHWRWGEPPVAVPAPQQADGNPDVPPPRPLQGR 545
>gi|158420731 chromodomain helicase DNA binding protein 3 isoform 3
[Homo sapiens]
Length = 2059
Score = 36.2 bits (82), Expect = 0.11
Identities = 22/74 (29%), Positives = 35/74 (47%), Gaps = 12/74 (16%)
Query: 342 DGY----QSYCTICCGGREVLMCGNNNCCRCFCVECVDLLVGPGAAQAAIKEDPWNCYMC 397
DGY Q YC +C G E+++C + C R + + C+D P +A E W+C C
Sbjct: 431 DGYETDHQDYCEVCQQGGEIILC--DTCPRAYHLVCLD----PELDRA--PEGKWSCPHC 482
Query: 398 GHKGTYGLLRRRED 411
+G + E+
Sbjct: 483 EKEGVQWEAKEEEE 496
Score = 30.0 bits (66), Expect = 7.9
Identities = 23/103 (22%), Positives = 37/103 (35%), Gaps = 8/103 (7%)
Query: 340 DDDGYQSYCTICCGGREVLMCGNNNCCRCFCVECVDLLVGPGAAQAAIKEDPWNCYMCGH 399
++D + YC +C G E+L C + C + + C++ I W C C
Sbjct: 510 EEDDHMEYCRVCKDGGELLCC--DACISSYHIHCLN------PPLPDIPNGEWLCPRCTC 561
Query: 400 KGTYGLLRRREDWPSRLQMFFANNHDQEFDPPKVYPPVPAEKR 442
G +++ W Q P V PP P + R
Sbjct: 562 PVLKGRVQKILHWRWGEPPVAVPAPQQADGNPDVPPPRPLQGR 604
>gi|126723060 zinc finger CCCH-type containing 4 [Homo sapiens]
Length = 1303
Score = 35.8 bits (81), Expect = 0.14
Identities = 24/91 (26%), Positives = 37/91 (40%), Gaps = 12/91 (13%)
Query: 26 EKKAKVIAGMNAVEENQGPGESQKVEEA------SPPAVQQPTDP------ASPTVATTP 73
E ++++ +NA + PG S K + + P +Q+PTD A P A P
Sbjct: 1044 ELLSRILKTVNATGSSAAPGSSDKPSDPRVRKAPTDPRLQKPTDSTASSRAAKPGPAEAP 1103
Query: 74 EPVGSDAGDKNATKAGDDEPEYEDGRGFGIG 104
P S +GD + +P G G G
Sbjct: 1104 SPTASPSGDASPPATAPYDPRVLAAGGLGQG 1134
>gi|4504191 mutS homolog 6 [Homo sapiens]
Length = 1360
Score = 35.0 bits (79), Expect = 0.24
Identities = 23/85 (27%), Positives = 29/85 (34%), Gaps = 22/85 (25%)
Query: 34 GMNAVEENQGPGESQKVEEASPPAVQQPTDPASPTVATTPEPVGSDAGDKNATKAGDDEP 93
G +A GPG ASPP + +VA P D
Sbjct: 45 GGDAAWSEAGPGPRPLARSASPPKAKNLNGGLRRSVAPAA-PTSCD-------------- 89
Query: 94 EYEDGRGFGIGELVWGKLRGFSWWP 118
F G+LVW K+ G+ WWP
Sbjct: 90 -------FSPGDLVWAKMEGYPWWP 107
>gi|14249464 zinc finger and BTB domain containing 45 [Homo sapiens]
Length = 511
Score = 34.3 bits (77), Expect = 0.42
Identities = 22/71 (30%), Positives = 35/71 (49%), Gaps = 14/71 (19%)
Query: 44 PGESQKVEEASPPAVQQPTDP---------ASPTVATTPEPVGSDAGDKNATKAGDDEPE 94
PG + ++ P +Q P P A P+++ P+ D GD++ ++ DDE +
Sbjct: 165 PGAAHSRKQRQPARLQLPAPPTPAKAEGPDADPSLSAAPD----DRGDEDDEES-DDETD 219
Query: 95 YEDGRGFGIGE 105
EDG G G GE
Sbjct: 220 GEDGEGGGPGE 230
>gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]
Length = 1312
Score = 33.9 bits (76), Expect = 0.54
Identities = 21/63 (33%), Positives = 29/63 (46%), Gaps = 1/63 (1%)
Query: 23 DTAEKKAKVIAGMNAVEENQGPGESQKVEEASPPAVQQPTDPASPTVATTPEPVGSDAGD 82
+ A ++A V G EE + E ++ EE PA T A+ +T P GS AGD
Sbjct: 1009 EEATEEAGVRGGAEEEEEEEEEEEEEEEEEEQQPATTTATSTAAAAPSTAPS-AGSTAGD 1067
Query: 83 KNA 85
A
Sbjct: 1068 SGA 1070
Score = 30.0 bits (66), Expect = 7.9
Identities = 25/96 (26%), Positives = 36/96 (37%), Gaps = 21/96 (21%)
Query: 16 RSLKDECDTAEKKAKVIAGMNAVEENQGPGESQKVEEAS-PPAVQQPTDPA--------- 65
+S D C A AG EE GE + + S PP P PA
Sbjct: 944 KSKADSCSQA-------AGTKGAEETSWSGEERAAKVPSTPPPKAAPPPPALTPDSQTVD 996
Query: 66 ----SPTVATTPEPVGSDAGDKNATKAGDDEPEYED 97
+P V+ PE +AG + + ++E E E+
Sbjct: 997 SSCKTPEVSFLPEEATEEAGVRGGAEEEEEEEEEEE 1032
>gi|56549129 transmembrane anchor protein 1 isoform 3 [Homo sapiens]
Length = 170
Score = 33.9 bits (76), Expect = 0.54
Identities = 22/55 (40%), Positives = 28/55 (50%), Gaps = 5/55 (9%)
Query: 53 ASPPAVQQPTDPASPTVAT-TPEPVGSDAGDKNATKAGDDEPEYEDGRGFGIGEL 106
ASP + P +PA P AT P P A + A+ AG +EP G G+GEL
Sbjct: 33 ASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEP----GEPAGLGEL 83
>gi|56549133 transmembrane anchor protein 1 isoform 2 [Homo sapiens]
Length = 177
Score = 33.9 bits (76), Expect = 0.54
Identities = 22/55 (40%), Positives = 28/55 (50%), Gaps = 5/55 (9%)
Query: 53 ASPPAVQQPTDPASPTVAT-TPEPVGSDAGDKNATKAGDDEPEYEDGRGFGIGEL 106
ASP + P +PA P AT P P A + A+ AG +EP G G+GEL
Sbjct: 33 ASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEP----GEPAGLGEL 83
>gi|56549131 transmembrane anchor protein 1 isoform 1 [Homo sapiens]
Length = 204
Score = 33.9 bits (76), Expect = 0.54
Identities = 22/55 (40%), Positives = 28/55 (50%), Gaps = 5/55 (9%)
Query: 53 ASPPAVQQPTDPASPTVAT-TPEPVGSDAGDKNATKAGDDEPEYEDGRGFGIGEL 106
ASP + P +PA P AT P P A + A+ AG +EP G G+GEL
Sbjct: 33 ASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEP----GEPAGLGEL 83
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.137 0.439
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,808,634
Number of Sequences: 37866
Number of extensions: 1641304
Number of successful extensions: 7661
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 43
Number of HSP's successfully gapped in prelim test: 49
Number of HSP's that attempted gapping in prelim test: 7457
Number of HSP's gapped (non-prelim): 228
length of query: 723
length of database: 18,247,518
effective HSP length: 110
effective length of query: 613
effective length of database: 14,082,258
effective search space: 8632424154
effective search space used: 8632424154
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.