Guide to the Human Genome
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Search of human proteins with 7706139

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7706139 hypothetical protein LOC51307 [Homo sapiens]
         (392 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|208431810 hypothetical protein LOC51307 [Homo sapiens]             820   0.0  
gi|7706139 hypothetical protein LOC51307 [Homo sapiens]               820   0.0  
gi|61966701 dorsal neural-tube nuclear protein [Homo sapiens]         130   2e-30
gi|47078281 hypothetical protein LOC9679 [Homo sapiens]               111   1e-24
gi|7657335 misshapen/NIK-related kinase isoform 1 [Homo sapiens]       52   7e-07
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         52   1e-06
gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens]      50   4e-06
gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom...    49   8e-06
gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom...    49   8e-06
gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sap...    49   8e-06
gi|118402590 myosin XV [Homo sapiens]                                  48   1e-05
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    48   2e-05
gi|171543895 ataxin 2 [Homo sapiens]                                   47   2e-05
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    47   4e-05
gi|61966919 hypothetical protein LOC442444 [Homo sapiens]              47   4e-05
gi|95147559 ankyrin repeat domain 43 [Homo sapiens]                    46   5e-05
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    45   1e-04
gi|163965366 nascent polypeptide-associated complex alpha subuni...    45   1e-04
gi|18079216 CASK interacting protein 1 [Homo sapiens]                  45   1e-04
gi|239754993 PREDICTED: hypothetical protein [Homo sapiens]            44   2e-04
gi|24797153 faciogenital dysplasia protein [Homo sapiens]              44   2e-04
gi|237757310 synaptojanin 1 isoform a [Homo sapiens]                   44   3e-04
gi|58530845 zyxin [Homo sapiens]                                       43   4e-04
gi|4508047 zyxin [Homo sapiens]                                        43   4e-04
gi|40556370 PHD finger protein 15 [Homo sapiens]                       43   4e-04
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre...    43   6e-04
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    42   7e-04
gi|56118221 amyloid beta (A4) precursor protein-binding, family ...    42   7e-04
gi|27436917 misshapen/NIK-related kinase isoform 3 [Homo sapiens]      42   7e-04
gi|47132519 Ras association and pleckstrin homology domains 1 is...    42   7e-04

>gi|208431810 hypothetical protein LOC51307 [Homo sapiens]
          Length = 392

 Score =  820 bits (2119), Expect = 0.0
 Identities = 392/392 (100%), Positives = 392/392 (100%)

Query: 1   MITLITEQLQKQTLDELKCTRFSISLPLPDHADISNCGNSFQLVSEGASWRGLPHCSCAE 60
           MITLITEQLQKQTLDELKCTRFSISLPLPDHADISNCGNSFQLVSEGASWRGLPHCSCAE
Sbjct: 1   MITLITEQLQKQTLDELKCTRFSISLPLPDHADISNCGNSFQLVSEGASWRGLPHCSCAE 60

Query: 61  FQDSLNFSYHPSGLSLHLRPPSRGNSPKEQPFSQVLRPEPPDPEKLPVPPAPPSKRHCRS 120
           FQDSLNFSYHPSGLSLHLRPPSRGNSPKEQPFSQVLRPEPPDPEKLPVPPAPPSKRHCRS
Sbjct: 61  FQDSLNFSYHPSGLSLHLRPPSRGNSPKEQPFSQVLRPEPPDPEKLPVPPAPPSKRHCRS 120

Query: 121 LSVPVDLSRWQPVWRPAPSKLWTPIKHRGSGGGGGPQVPHQSPPKRVSSLRFLQAPSASS 180
           LSVPVDLSRWQPVWRPAPSKLWTPIKHRGSGGGGGPQVPHQSPPKRVSSLRFLQAPSASS
Sbjct: 121 LSVPVDLSRWQPVWRPAPSKLWTPIKHRGSGGGGGPQVPHQSPPKRVSSLRFLQAPSASS 180

Query: 181 QCAPAHRPYSPPFFSLALAQDSSRPCAASPQSGSWESDAESLSPCPPQRRFSLSPSLGPQ 240
           QCAPAHRPYSPPFFSLALAQDSSRPCAASPQSGSWESDAESLSPCPPQRRFSLSPSLGPQ
Sbjct: 181 QCAPAHRPYSPPFFSLALAQDSSRPCAASPQSGSWESDAESLSPCPPQRRFSLSPSLGPQ 240

Query: 241 ASRFLPSARSSPASSPELPWRPRGLRNLPRSRSQPCDLDARKTGVKRRHEEDPRRLRPSL 300
           ASRFLPSARSSPASSPELPWRPRGLRNLPRSRSQPCDLDARKTGVKRRHEEDPRRLRPSL
Sbjct: 241 ASRFLPSARSSPASSPELPWRPRGLRNLPRSRSQPCDLDARKTGVKRRHEEDPRRLRPSL 300

Query: 301 DFDKMNQKPYSGGLCLQETAREGSSISPPWFMACSPPPLSASCSPTGGSSQVLSESEEEE 360
           DFDKMNQKPYSGGLCLQETAREGSSISPPWFMACSPPPLSASCSPTGGSSQVLSESEEEE
Sbjct: 301 DFDKMNQKPYSGGLCLQETAREGSSISPPWFMACSPPPLSASCSPTGGSSQVLSESEEEE 360

Query: 361 EGAVRWGRQALSKRTLCQRDFGDLDLNLIEEN 392
           EGAVRWGRQALSKRTLCQRDFGDLDLNLIEEN
Sbjct: 361 EGAVRWGRQALSKRTLCQRDFGDLDLNLIEEN 392


>gi|7706139 hypothetical protein LOC51307 [Homo sapiens]
          Length = 392

 Score =  820 bits (2119), Expect = 0.0
 Identities = 392/392 (100%), Positives = 392/392 (100%)

Query: 1   MITLITEQLQKQTLDELKCTRFSISLPLPDHADISNCGNSFQLVSEGASWRGLPHCSCAE 60
           MITLITEQLQKQTLDELKCTRFSISLPLPDHADISNCGNSFQLVSEGASWRGLPHCSCAE
Sbjct: 1   MITLITEQLQKQTLDELKCTRFSISLPLPDHADISNCGNSFQLVSEGASWRGLPHCSCAE 60

Query: 61  FQDSLNFSYHPSGLSLHLRPPSRGNSPKEQPFSQVLRPEPPDPEKLPVPPAPPSKRHCRS 120
           FQDSLNFSYHPSGLSLHLRPPSRGNSPKEQPFSQVLRPEPPDPEKLPVPPAPPSKRHCRS
Sbjct: 61  FQDSLNFSYHPSGLSLHLRPPSRGNSPKEQPFSQVLRPEPPDPEKLPVPPAPPSKRHCRS 120

Query: 121 LSVPVDLSRWQPVWRPAPSKLWTPIKHRGSGGGGGPQVPHQSPPKRVSSLRFLQAPSASS 180
           LSVPVDLSRWQPVWRPAPSKLWTPIKHRGSGGGGGPQVPHQSPPKRVSSLRFLQAPSASS
Sbjct: 121 LSVPVDLSRWQPVWRPAPSKLWTPIKHRGSGGGGGPQVPHQSPPKRVSSLRFLQAPSASS 180

Query: 181 QCAPAHRPYSPPFFSLALAQDSSRPCAASPQSGSWESDAESLSPCPPQRRFSLSPSLGPQ 240
           QCAPAHRPYSPPFFSLALAQDSSRPCAASPQSGSWESDAESLSPCPPQRRFSLSPSLGPQ
Sbjct: 181 QCAPAHRPYSPPFFSLALAQDSSRPCAASPQSGSWESDAESLSPCPPQRRFSLSPSLGPQ 240

Query: 241 ASRFLPSARSSPASSPELPWRPRGLRNLPRSRSQPCDLDARKTGVKRRHEEDPRRLRPSL 300
           ASRFLPSARSSPASSPELPWRPRGLRNLPRSRSQPCDLDARKTGVKRRHEEDPRRLRPSL
Sbjct: 241 ASRFLPSARSSPASSPELPWRPRGLRNLPRSRSQPCDLDARKTGVKRRHEEDPRRLRPSL 300

Query: 301 DFDKMNQKPYSGGLCLQETAREGSSISPPWFMACSPPPLSASCSPTGGSSQVLSESEEEE 360
           DFDKMNQKPYSGGLCLQETAREGSSISPPWFMACSPPPLSASCSPTGGSSQVLSESEEEE
Sbjct: 301 DFDKMNQKPYSGGLCLQETAREGSSISPPWFMACSPPPLSASCSPTGGSSQVLSESEEEE 360

Query: 361 EGAVRWGRQALSKRTLCQRDFGDLDLNLIEEN 392
           EGAVRWGRQALSKRTLCQRDFGDLDLNLIEEN
Sbjct: 361 EGAVRWGRQALSKRTLCQRDFGDLDLNLIEEN 392


>gi|61966701 dorsal neural-tube nuclear protein [Homo sapiens]
          Length = 398

 Score =  130 bits (327), Expect = 2e-30
 Identities = 140/425 (32%), Positives = 182/425 (42%), Gaps = 60/425 (14%)

Query: 1   MITLITEQLQKQTLDELKCTRFSISLPLPDHADISN-CGNSFQL-VSEGASWR----GLP 54
           M+TLITE+LQ Q+LD+L C   + + PL   A+  N  G  F L +++ + W+    G P
Sbjct: 1   MVTLITEKLQSQSLDDLTCK--AEAGPLQYSAETLNKSGRLFPLELNDQSPWKVFSGGPP 58

Query: 55  HCSCA------EFQDSLNFSYHPSGLSLHLRPPSRGNSPKEQPFSQVLRPEPPDP-EKLP 107
             S A       F   L+ + H  GL    + P        +P + +      DP E   
Sbjct: 59  VRSQAATGPDFSFLPGLSAAAHTMGLQWQPQSP--------RPGAGLGAASTVDPSESTG 110

Query: 108 VPPAPPSKRHCRSLSVPVDLSRWQPVWRPAPSKLWTPIKHRGSGGGGGPQVPHQSPPKRV 167
              APP+KRHCRSLS P +L R +  WRP  SK+WTP+  R    GG      Q  P  V
Sbjct: 111 SSTAPPTKRHCRSLSEPEELVRCRSPWRPGSSKVWTPVSKRRCDSGG--SATRQGSPGAV 168

Query: 168 SSLRFLQAPSASSQCAPAHRPYSPPFFSLALAQDSSRPCAASPQSGSWESDAESLSPCPP 227
                + +   +S   P     S  F       DSS     S  SG     AES  P   
Sbjct: 169 LPRSAVWSTGPTSPATPRPSSASGGFV------DSSE---GSAGSGPLWCSAESCLP-ST 218

Query: 228 QRRFSLSPSLGPQASRFLPSARSSPASSPELPWRPRGLRNLPRSRSQPCDLDARKTGVKR 287
           +RR SLS      A   LP A SSP S+P L     G R L R RSQPC L  +++  KR
Sbjct: 219 RRRPSLSQERLAGAGTPLPWASSSPTSTPAL----GGRRGLLRCRSQPCVLSGKRSRRKR 274

Query: 288 RHEEDPRRLRPSLDFDKMNQK-PYSGGLCLQETAREGSSISPPWFMACSP------PPLS 340
           R EED R  RPSLDF KM Q    S  LC      +    +P   +  SP      P ++
Sbjct: 275 RREEDARWTRPSLDFLKMTQTLKNSKSLCSLNYEDDDEDDTPVKTVLSSPCDSRGLPGIT 334

Query: 341 -ASCSPTG------------GSSQVLSESEEEEEGAVRWGRQALSKRTLCQRDFGDLDLN 387
              CS  G                V S+      G  R G  ++ +  +  R   +LDL 
Sbjct: 335 MPGCSQRGLRTSPVHPNLWASRESVTSDGSRRSSGDPRDG-DSVGEEGVFPRARWELDLE 393

Query: 388 LIEEN 392
            IE N
Sbjct: 394 QIENN 398


>gi|47078281 hypothetical protein LOC9679 [Homo sapiens]
          Length = 422

 Score =  111 bits (277), Expect = 1e-24
 Identities = 103/329 (31%), Positives = 136/329 (41%), Gaps = 56/329 (17%)

Query: 109 PPAPPSKRHCRSLSVPVDLSRWQPVWRPAPSKLWTPIKHRGSGGGGGPQVPHQSPPKRVS 168
           P APPSKR CRSLS   ++S  +  WRP  SK+WTP++ R    GG  Q       +  +
Sbjct: 105 PSAPPSKRQCRSLSFSDEMSSCRTSWRPLGSKVWTPVEKRRCYSGGSVQ-------RYSN 157

Query: 169 SLRFLQAPSASSQCAPAHRPYSPPFFSLALAQDSSRPCAASPQSGSWESDAESLSP---- 224
               +Q  S+ S  + A+   SP   +    +   +PC   P S       ++ SP    
Sbjct: 158 GFSTMQRSSSFSLPSRANVLSSPCDQAGLHHRFGGQPCQGVPGSAPCGQAGDTWSPDLHP 217

Query: 225 -----CPPQRRFSLSPSLGPQASRFLPSARSSPASSPELPWRPRGLRNLPRSRSQPCDLD 279
                   QR  S S           PSA S+PAS+PEL  R  G   L RSRSQPC L+
Sbjct: 218 VGGGRLDLQRSLSCSHEQFSFVEYCPPSANSTPASTPELARRSSG---LSRSRSQPCVLN 274

Query: 280 ARKTGVKRRHEEDPRRLRPSLDFDKM--NQKPYSGGLCLQETAREGSSISP--------- 328
            +K GVKRR  E+ +  RPSLD  KM  N + +S   CL     +    SP         
Sbjct: 275 DKKVGVKRRRPEEVQEQRPSLDLAKMAQNCQTFSSLSCLSAGTEDCGPQSPFARHVSNTR 334

Query: 329 PWFMACS--------------PPPLSASCSPTGGSSQVLSESEEEE-----------EGA 363
            W    S              P PL  S        + LS  E +            E A
Sbjct: 335 AWTALLSASGPGGRTPAGTPVPEPLPPSFDDHLACQEDLSCEESDSCALDEDCGRRAEPA 394

Query: 364 VRWGRQALSKRTLCQRDFGDLDLNLIEEN 392
             W  +     +LC  D G+LD+  IE+N
Sbjct: 395 AAWRDRGAPGNSLCSLD-GELDIEQIEKN 422


>gi|7657335 misshapen/NIK-related kinase isoform 1 [Homo sapiens]
          Length = 1295

 Score = 52.4 bits (124), Expect = 7e-07
 Identities = 82/323 (25%), Positives = 119/323 (36%), Gaps = 54/323 (16%)

Query: 85  NSPKEQPFSQVLRPEPPDPEKLPVPPAPPSKRHCRSLSVPVDLSRWQPVWRPAPSKLWTP 144
           NSP  +       PEPP P+  P PP P              LS+  P+ RP   +    
Sbjct: 534 NSPLAKSKPGSTGPEPPIPQASPGPPGP--------------LSQTPPMQRPVEPQ---E 576

Query: 145 IKHRGSGGGGGPQVPHQSPPKRVSSL-----RFLQAPSASSQCAPA-HRPYSPPFFSLAL 198
             H+       P  P+ +P  R  SL     R L A  AS    PA   P + P    A+
Sbjct: 577 GPHKSLVAHRVPLKPYAAPVPRSQSLQDQPTRNLAAFPASHDPDPAIPAPTATPSARGAV 636

Query: 199 AQDSSRPCA----ASPQSGSWESDAESLSPCPPQRRFSLSPSLGPQASRFLPSARSSPAS 254
            + +S P +     SP   +W        P  PQR  S++ +L    +     A++  AS
Sbjct: 637 IRQNSDPTSEGPGPSPNPPAWVRPDNEAPPKVPQRTSSIATALNTSGAGGSRPAQAVRAS 696

Query: 255 SPEL----PWRPRGLRNLPRSRS---QPCDLDARKTGVKRRHEEDP-----RRLRPSLDF 302
           +P+L    P   R    LP S     Q   L+  + GV  + +  P      + +P  D 
Sbjct: 697 NPDLRRSDPGWERSDSVLPASHGHLPQAGSLERNRVGVSSKPDSSPVLSPGNKAKPD-DH 755

Query: 303 DKMNQKPYSGGLCLQETAREGSSISPPWFMACSPPPLSASCSPTGGSSQVLSESEEEEEG 362
                +P    L  + T  E            +P P   +   +  S +V S  ++EEEG
Sbjct: 756 RSRPGRPADFVLLKERTLDE------------APRPPKKAMDYSSSSEEVESSEDDEEEG 803

Query: 363 AVRWGRQALSKRTLCQRDFGDLD 385
               G    S+ T   R  GD D
Sbjct: 804 --EGGPAEGSRDTPGGRSDGDTD 824


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 62/249 (24%), Positives = 95/249 (38%), Gaps = 25/249 (10%)

Query: 80  PPSRGNSPKEQPFSQVLR----PEPPDPEKLPVPPAPPSKRHC-------RSLSVPVDLS 128
           PP R  SP  + +S  ++    P PP   +   PP PP +R         R    P    
Sbjct: 584 PPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQ 643

Query: 129 RWQPVWRPAPSKLWTPIKHRGSGGGGGPQVPHQSPPKRVSSLRFLQAPSASSQCAPAHRP 188
           R  PV +     L +  +   S      +     P KR S     +AP  SS   P  R 
Sbjct: 644 RSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRG 703

Query: 189 YSPPFFSLALAQDSSRPCAASPQSGSWESDAESLSPCPPQ-RRFSLSPSL--GPQASRFL 245
            S           S+RP     ++   +   ++ SP P   RR S S S+   P+ +   
Sbjct: 704 ASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKK 763

Query: 246 PSARSSP--ASSPELPWRP----RGLRNLPRSRSQPCDLDARKTGVKRRHEEDPRRLRPS 299
           P A  SP  + SP   W P    +  ++   S S P + D    G K++ ++D +  +  
Sbjct: 764 PPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHKK-- 821

Query: 300 LDFDKMNQK 308
              DK ++K
Sbjct: 822 ---DKKHKK 827



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 58/237 (24%), Positives = 88/237 (37%), Gaps = 23/237 (9%)

Query: 75  SLHLRPPSRGNSPKEQPFSQVLRPEPPDPEKLPVPPAPPSKRHCRSLSVPVDLSRWQPVW 134
           S+ ++ PS   +       +V +PEP    K P P     K   +  + P   SR +   
Sbjct: 227 SVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRS 286

Query: 135 RP---APSKLWTPIKHRGSGGGGGPQVPHQSPPKRVSSLRFLQAPSASSQCAPAHRPYSP 191
           R    +PS      +HR       P+    SP +R S  R  + P       P HR    
Sbjct: 287 RTRSRSPSHTRPRRRHRSRSRSYSPR-RRPSPRRRPSPRR--RTPPRRMPPPPRHRRSRS 343

Query: 192 PFFSLALAQDSSRPCAASPQSGSWESDAESLSP---------CPPQRRFSLSPSLGPQAS 242
           P       +   R  A+   S S  S + S SP          PP++   LSPS  P   
Sbjct: 344 P------VRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRR 397

Query: 243 RFLPSARSSPASSPELPWRPRGLRNLPRSRSQPCDLDARKTGVKRRHEEDPRRLRPS 299
           R  PS  ++P   P+    P   ++    +S+      R +G   +H+   +R  PS
Sbjct: 398 RHRPSPPATP--PPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPS 452



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 77/331 (23%), Positives = 109/331 (32%), Gaps = 21/331 (6%)

Query: 57  SCAEFQDSLNFSYHPSGLSLHLRPPSRGNSPKEQPFSQVLRPEPPDPEKLPVPPA--PPS 114
           S A    S + S      S   +PP R +SP  +         PP     P PPA  PP 
Sbjct: 351 SSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPK 410

Query: 115 KRHCRSLSVPVDLSRWQPVWRPAPSKLWTPIKHRGSGGGGGPQ-VPHQSPPKRVSSLRFL 173
            RH  +        + +    P  +      KH+G+     P   P     +   S    
Sbjct: 411 TRHSPTPQQSNRTRKSRVSVSPGRTS-GKVTKHKGTEKRESPSPAPKPRKVELSESEEDK 469

Query: 174 QAPSASSQCAPAHRPY------SPPFFSLALAQDSSRPCAASPQSGSW-----ESDAESL 222
               A++      R Y      S      + + +  RP  +  ++G        S + S 
Sbjct: 470 GGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSA 529

Query: 223 SPCPPQRRFSLSPSLGPQASRFLPSARSSPASSPELPWRPRGLRNLPRSRSQPCDLDARK 282
           SP P +R+   SP    + S   P  R   + SP  P R R     P  R  P     R+
Sbjct: 530 SPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRR 589

Query: 283 TGVKRRHEED-PRRLRPSLDFDKMNQKPYSGGLCLQETAREGSSISPPWFMACSPPPLSA 341
           +   RR+     RR  PS    +    P           R   S  P   ++ SPPP   
Sbjct: 590 SPSPRRYSPPIQRRYSPSPPPKRRTASPPP-----PPKRRASPSPPPKRRVSHSPPPKQR 644

Query: 342 SCSPTGGSSQVLSESEEEEEGAVRWGRQALS 372
           S   T   S  LS    +     R  R+A S
Sbjct: 645 SSPVTKRRSPSLSSKHRKGSSPSRSTREARS 675


>gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens]
          Length = 1303

 Score = 50.1 bits (118), Expect = 4e-06
 Identities = 81/323 (25%), Positives = 120/323 (37%), Gaps = 46/323 (14%)

Query: 85  NSPKEQPFSQVLRPEPPDPEKLPVPPAPPSKRHCRSLSVPVDLSRWQPVWRPAPSKLWTP 144
           NSP  +       PEPP P+  P PP P              LS+  P+ RP   +    
Sbjct: 534 NSPLAKSKPGSTGPEPPIPQASPGPPGP--------------LSQTPPMQRPVEPQ---E 576

Query: 145 IKHRGSGGGGGPQVPHQSPPKRVSSL-----RFLQAPSASSQCAPA-HRPYSPPFFSLAL 198
             H+       P  P+ +P  R  SL     R L A  AS    PA   P + P    A+
Sbjct: 577 GPHKSLVAHRVPLKPYAAPVPRSQSLQDQPTRNLAAFPASHDPDPAIPAPTATPSARGAV 636

Query: 199 AQDSSRPCA----ASPQSGSWESDAESLSPCPPQRRFSLSPSLGPQASRFLPSARSSPAS 254
            + +S P +     SP   +W        P  PQR  S++ +L    +     A++  AS
Sbjct: 637 IRQNSDPTSEGPGPSPNPPAWVRPDNEAPPKVPQRTSSIATALNTSGAGGSRPAQAVRAS 696

Query: 255 SPEL----PWRPRGLRNLPRSRS---QPCDLDARKTGVKRRHEEDP-----RRLRPSLDF 302
           +P+L    P   R    LP S     Q   L+  + GV  + +  P      + +P  D 
Sbjct: 697 NPDLRRSDPGWERSDSVLPASHGHLPQAGSLERNRVGVSSKPDSSPVLSPGNKAKPD-DH 755

Query: 303 DKMNQKPYSGGLCLQETAREGSSISPPWFMACSPPPLSASCSPTGGSSQVLSESEEEEEG 362
                +P S     +    E   +     +  +P P   +   +  S +V S  ++EEEG
Sbjct: 756 RSRPGRPAS----YKRAIGEDFVLLKERTLDEAPRPPKKAMDYSSSSEEVESSEDDEEEG 811

Query: 363 AVRWGRQALSKRTLCQRDFGDLD 385
               G    S+ T   R  GD D
Sbjct: 812 --EGGPAEGSRDTPGGRSDGDTD 832


>gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo
           sapiens]
          Length = 1188

 Score = 48.9 bits (115), Expect = 8e-06
 Identities = 59/233 (25%), Positives = 90/233 (38%), Gaps = 56/233 (24%)

Query: 87  PKEQPFSQVLRPEPPDPEKLPVPPAPPSKRHCRS-LSVPVDLSRWQ----------PVWR 135
           P   P + +  P PP P   P PPAP S     + L  P  +++W+             R
Sbjct: 216 PPAPPLAFLAPPPPPVP--APAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATR 273

Query: 136 PAPSKLWTPIKHRGSGGGGGPQVPHQSPPK----------RVSSLRFLQAPSA------S 179
            +P +  +P + +GS  G  P+ PH + P+          R SS+   +A  A      +
Sbjct: 274 ASPPR--SPAEPKGSALGPNPE-PHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGA 330

Query: 180 SQCAPAHRPYSPPFFSLALAQ-------------DSSRPCAASPQSGSWESDAESLSPCP 226
           ++ AP+  P  P F     +Q             +      ASP+ G  +S A+  +  P
Sbjct: 331 TKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTP 390

Query: 227 PQRRFSLSPSLGPQASRFLPSARSSPASSPELPWR------PRGLRNLPRSRS 273
           P      +P L P A    P A   P ++P LP        P G    P+S S
Sbjct: 391 PP-----APPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSS 438



 Score = 30.0 bits (66), Expect = 3.8
 Identities = 33/118 (27%), Positives = 46/118 (38%), Gaps = 24/118 (20%)

Query: 70   HPSGLSLHLRP-PSRGNSPKEQPFSQVLRPEPPDPEKLPVPPAPPSKRHCRSLSVP---- 124
            HP   S    P PS     +E+ F+  + P PP+    P PPAP  +   R  S P    
Sbjct: 958  HPLPKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSNDPEPPAPALQYLGRQSSPPRNNY 1017

Query: 125  VDLSRWQPVWRPAP-----SKLWTPIKHRGSGG-----GGGPQV---------PHQSP 163
             DL +       AP     S+     ++ G+GG     GGG  +         PH+ P
Sbjct: 1018 SDLRQLPNAGPGAPPALGFSRFPAGARYAGAGGLERFSGGGRSLIKKRLYVGEPHRGP 1075


>gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo
           sapiens]
          Length = 1188

 Score = 48.9 bits (115), Expect = 8e-06
 Identities = 59/233 (25%), Positives = 90/233 (38%), Gaps = 56/233 (24%)

Query: 87  PKEQPFSQVLRPEPPDPEKLPVPPAPPSKRHCRS-LSVPVDLSRWQ----------PVWR 135
           P   P + +  P PP P   P PPAP S     + L  P  +++W+             R
Sbjct: 216 PPAPPLAFLAPPPPPVP--APAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATR 273

Query: 136 PAPSKLWTPIKHRGSGGGGGPQVPHQSPPK----------RVSSLRFLQAPSA------S 179
            +P +  +P + +GS  G  P+ PH + P+          R SS+   +A  A      +
Sbjct: 274 ASPPR--SPAEPKGSALGPNPE-PHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGA 330

Query: 180 SQCAPAHRPYSPPFFSLALAQ-------------DSSRPCAASPQSGSWESDAESLSPCP 226
           ++ AP+  P  P F     +Q             +      ASP+ G  +S A+  +  P
Sbjct: 331 TKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTP 390

Query: 227 PQRRFSLSPSLGPQASRFLPSARSSPASSPELPWR------PRGLRNLPRSRS 273
           P      +P L P A    P A   P ++P LP        P G    P+S S
Sbjct: 391 PP-----APPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSS 438



 Score = 30.0 bits (66), Expect = 3.8
 Identities = 33/118 (27%), Positives = 46/118 (38%), Gaps = 24/118 (20%)

Query: 70   HPSGLSLHLRP-PSRGNSPKEQPFSQVLRPEPPDPEKLPVPPAPPSKRHCRSLSVP---- 124
            HP   S    P PS     +E+ F+  + P PP+    P PPAP  +   R  S P    
Sbjct: 958  HPLPKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSNDPEPPAPALQYLGRQSSPPRNNY 1017

Query: 125  VDLSRWQPVWRPAP-----SKLWTPIKHRGSGG-----GGGPQV---------PHQSP 163
             DL +       AP     S+     ++ G+GG     GGG  +         PH+ P
Sbjct: 1018 SDLRQLPNAGPGAPPALGFSRFPAGARYAGAGGLERFSGGGRSLIKKRLYVGEPHRGP 1075


>gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo
           sapiens]
          Length = 1188

 Score = 48.9 bits (115), Expect = 8e-06
 Identities = 59/233 (25%), Positives = 90/233 (38%), Gaps = 56/233 (24%)

Query: 87  PKEQPFSQVLRPEPPDPEKLPVPPAPPSKRHCRS-LSVPVDLSRWQ----------PVWR 135
           P   P + +  P PP P   P PPAP S     + L  P  +++W+             R
Sbjct: 216 PPAPPLAFLAPPPPPVP--APAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATR 273

Query: 136 PAPSKLWTPIKHRGSGGGGGPQVPHQSPPK----------RVSSLRFLQAPSA------S 179
            +P +  +P + +GS  G  P+ PH + P+          R SS+   +A  A      +
Sbjct: 274 ASPPR--SPAEPKGSALGPNPE-PHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGA 330

Query: 180 SQCAPAHRPYSPPFFSLALAQ-------------DSSRPCAASPQSGSWESDAESLSPCP 226
           ++ AP+  P  P F     +Q             +      ASP+ G  +S A+  +  P
Sbjct: 331 TKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTP 390

Query: 227 PQRRFSLSPSLGPQASRFLPSARSSPASSPELPWR------PRGLRNLPRSRS 273
           P      +P L P A    P A   P ++P LP        P G    P+S S
Sbjct: 391 PP-----APPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSS 438



 Score = 30.0 bits (66), Expect = 3.8
 Identities = 33/118 (27%), Positives = 46/118 (38%), Gaps = 24/118 (20%)

Query: 70   HPSGLSLHLRP-PSRGNSPKEQPFSQVLRPEPPDPEKLPVPPAPPSKRHCRSLSVP---- 124
            HP   S    P PS     +E+ F+  + P PP+    P PPAP  +   R  S P    
Sbjct: 958  HPLPKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSNDPEPPAPALQYLGRQSSPPRNNY 1017

Query: 125  VDLSRWQPVWRPAP-----SKLWTPIKHRGSGG-----GGGPQV---------PHQSP 163
             DL +       AP     S+     ++ G+GG     GGG  +         PH+ P
Sbjct: 1018 SDLRQLPNAGPGAPPALGFSRFPAGARYAGAGGLERFSGGGRSLIKKRLYVGEPHRGP 1075


>gi|118402590 myosin XV [Homo sapiens]
          Length = 3530

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 90/312 (28%), Positives = 118/312 (37%), Gaps = 74/312 (23%)

Query: 79  RPPSRGNSPKE-QPFSQVLRPE-PPDPEKLPVPPAPPSKRHCRSLSVPV----DLSRWQP 132
           RPP+   +P+    +S +L P  PP P     PPAPP       L  P      L R  P
Sbjct: 643 RPPAPQPAPRTLSHWSALLSPPVPPRPPSSGPPPAPPLSPALSGLPRPASPYGSLRRHPP 702

Query: 133 VWR------PAPSKLW---------TPIKHRGSGGGGGPQVPHQSPPKRVSSLRFLQAPS 177
            W       PAP   W         +P          GP+   +   +R ++  F   P 
Sbjct: 703 PWAAPAHVPPAPQASWWAFVEPPAVSPEVPPDLLAFPGPRPSFRGSRRRGAAFGF---PG 759

Query: 178 ASSQCAPAHRPYSPPFFSLALAQDSSRPCAASPQSGSWESDAESLSPCPPQRRFSLSPSL 237
           AS + A   R +SP    LA  Q S R   +SP  G        L+P  PQ    LS   
Sbjct: 760 ASPR-ASRRRAWSP----LASPQPSLR---SSPGLGY----CSPLAPPSPQ----LSLRT 803

Query: 238 GPQASRFLPSAR------SSPA----------------SSPELPWRPRGLRNLPRSRSQP 275
           GP    FLP AR       SPA                 SP  P  P GL + PR  S  
Sbjct: 804 GPFQPPFLPPARRPRSLQESPAPRRAAGRLGPPGSPLPGSPRPPSPPLGLCHSPRRSS-- 861

Query: 276 CDLDARKTGVKRRHEEDP-RRLRPSLDFDKMNQKPYSGG----LCLQETAREGSSISPPW 330
            +L +R     RR  E P R ++P +     ++ P +G     L  +E+ RE      PW
Sbjct: 862 LNLPSRLPHTWRRLSEPPTRAVKPQVRL-PFHRPPRAGAWRAPLEHRESPREPEDSETPW 920

Query: 331 FMACSPPPLSAS 342
               + PPL+ S
Sbjct: 921 ----TVPPLAPS 928



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 67/233 (28%), Positives = 83/233 (35%), Gaps = 31/233 (13%)

Query: 78   LRPPSRGNSPKEQPFSQVLRPEPPDPEKLPVPPAPPSKRHCRSLSVPVDLSRWQPVWRPA 137
            L PPS   S +  PF     P    P  L   PAP  +R    L  P       P  RP 
Sbjct: 792  LAPPSPQLSLRTGPFQPPFLPPARRPRSLQESPAP--RRAAGRLGPPGSPLPGSP--RPP 847

Query: 138  PSKLWTPIKHRGSGGGGGPQVPH-----QSPPKRVSS----LRFLQAPSASSQCAPAHRP 188
               L      R S      ++PH       PP R       L F + P A +  AP    
Sbjct: 848  SPPLGLCHSPRRSSLNLPSRLPHTWRRLSEPPTRAVKPQVRLPFHRPPRAGAWRAPLEHR 907

Query: 189  YSPPFFSLALAQDSSRPCAASPQSGSWESDAESLSPCPPQRRFSLSPSLGPQASRFLPSA 248
             SP        +DS  P    P + SW+ D       PP +R   SP  G   SR     
Sbjct: 908  ESP-----REPEDSETPWTVPPLAPSWDVD------MPPTQR-PPSPWPGGAGSR---RG 952

Query: 249  RSSPASSPELPWRPRGLRNLPRSRSQPCD--LDARKTGVKRRHEEDPRRLRPS 299
             S P   PE P+  + L  +P    QP D   D  +  + R HE  P +L  S
Sbjct: 953  FSRPPPVPENPFL-QLLGPVPSPTLQPEDPAADMTRVFLGRHHEPGPGQLTKS 1004


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
           sapiens]
          Length = 5537

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 65/217 (29%), Positives = 77/217 (35%), Gaps = 42/217 (19%)

Query: 74  LSLHLRPPSRGNSPKEQPFSQVLRPEPPDPEKLPVPPAPPSKRHCRSLSVPVDLSRWQPV 133
           L   L PP    SP   PF +   P  P PE+LP  P P + R    LS P + S   P 
Sbjct: 532 LETPLSPPPEA-SPLSPPFEE--SPLSPPPEELPTSPPPEASR----LSPPPEESPMSPP 584

Query: 134 WRPAP-------SKLWTPIKHRGSGGGGGPQVPHQSPPKRVSSLRFLQAPSASSQCAPAH 186
              +P       S+L+ P +   S     P+    SPP   S L      S  S   P  
Sbjct: 585 PEESPMSPPPEASRLFPPFEE--SPLSPPPEESPLSPPPEASRLSPPPEDSPMSP-PPEE 641

Query: 187 RPYSPP-----FFSLALAQDSSRPCAASPQSGSWESDAESLSPCPPQRRFSLSPSLGPQA 241
            P SPP        L +    S P   SP S             PP      SP   P+A
Sbjct: 642 SPMSPPPEVSRLSPLPVVSRLSPPPEESPLS-------------PPPEESPTSPP--PEA 686

Query: 242 SRFLPSARSSPAS-----SPELPWRPRGLRNLPRSRS 273
           SR  P    SP S     SP  P     L +LP   S
Sbjct: 687 SRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEES 723



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 72/262 (27%), Positives = 92/262 (35%), Gaps = 51/262 (19%)

Query: 89  EQPFSQVLRPEPPDPEKLPVPPAPPSKRHCRSLSVPVDLSRWQPVWRPAPSKLWTPIKHR 148
           E P ++ + P  P PE+ P+ P P         S P + SR  P     P+   +P+   
Sbjct: 431 EAPLNEEM-PLLPPPEESPLSPPPEES----PTSPPPEASRLSPPPEELPA---SPL--- 479

Query: 149 GSGGGGGPQVPHQSPPKRVSSLRFLQAPSASSQCAPAHRPYSPPFFSLALAQDSSRPCAA 208
                  P+  H S P   S L     P   S  +P   P S PF           P   
Sbjct: 480 -------PEALHLSRPLEESPL---SPPPEESPLSPP--PESSPF----------SPLEE 517

Query: 209 SPQSGSWESDAESLSPCPPQRRFSLSPSLGPQASRFLPSARSSPASSP--ELPWR--PRG 264
           SP S   ES      P  P     LSP   P+AS   P    SP S P  ELP    P  
Sbjct: 518 SPLSPPEES------PPSPALETPLSPP--PEASPLSPPFEESPLSPPPEELPTSPPPEA 569

Query: 265 LRNLPRSRSQPCDLDARKTGVKRRHEEDPRRLRPSLDFDKMNQKPYSGGLCLQETAREGS 324
            R  P     P      ++ +    E    RL P  +   ++  P    L       E S
Sbjct: 570 SRLSPPPEESPMSPPPEESPMSPPPEAS--RLFPPFEESPLSPPPEESPL---SPPPEAS 624

Query: 325 SIS-PPWFMACSPPPLSASCSP 345
            +S PP     SPPP  +  SP
Sbjct: 625 RLSPPPEDSPMSPPPEESPMSP 646



 Score = 39.7 bits (91), Expect = 0.005
 Identities = 61/224 (27%), Positives = 78/224 (34%), Gaps = 39/224 (17%)

Query: 71   PSGLSLHLRPPSRGNSPKEQPFSQVLRPEPP------------DPEKLP---VPPAPPSK 115
            P    +  + P  G  P+E P +Q L P PP            DP   P     P PP  
Sbjct: 2333 PRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPP 2392

Query: 116  RHCRSL---SVPVDLSRWQPVWRPAPSKLWTPIKHRGSGGGG---GPQVPHQSPPKRVSS 169
              C +L   S+P D     P    + S   +P+  R          P  P    P   S 
Sbjct: 2393 ESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYS- 2451

Query: 170  LRFLQAPSASSQCAPAHRPYSP-----PFFSLALAQDSSRP---CAASPQSGSWESDAES 221
             R    P +    AP H+P  P      F + +LA  S       AA P   + E  A+ 
Sbjct: 2452 -RPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKV 2510

Query: 222  LSPCPPQRRFSLSPSLG-----PQASRF-LPSARSSPASSPELP 259
             S  PP   F  SP  G     P   RF  P A   P+  P +P
Sbjct: 2511 PSGQPP--NFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVP 2552



 Score = 38.9 bits (89), Expect = 0.008
 Identities = 60/241 (24%), Positives = 78/241 (32%), Gaps = 43/241 (17%)

Query: 54   PHCSCAEFQDSLNFSYHPSGLSLHLRPPSRGNSPKEQPFSQVL-------RPEPPD---- 102
            PH S    +  L+     S LS     P     P+E   S  L       RPE P     
Sbjct: 813  PHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPG 872

Query: 103  ----PEKLPVPPAPPSKRHCRSLSVPVDLSRWQPVWRPAPSKLWTPIKHRGSGGGGGPQV 158
                PE+LP+ P P        L  P      +P   P P +L  P+   G        +
Sbjct: 873  QCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEEL--PLSPSGEPSLSPQLM 930

Query: 159  PHQSPPKRVSSLRFLQAPSASSQCAPAHRPY---------------------SPPFFSLA 197
            P    P  +S +    AP A S       P+                     SPP  +  
Sbjct: 931  PPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANC 990

Query: 198  LAQDSSRPCAASPQSGSWESDAES--LSPCPPQRRFSLSPSLGPQASRFLPSARSSPASS 255
               +   P    P  GS    A    + P PPQ    L  SL PQ S   P ++ SP + 
Sbjct: 991  TDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNS---PPSQCSPPAL 1047

Query: 256  P 256
            P
Sbjct: 1048 P 1048



 Score = 37.4 bits (85), Expect = 0.024
 Identities = 57/203 (28%), Positives = 72/203 (35%), Gaps = 39/203 (19%)

Query: 77  HLRPPSRGNSPKEQPFSQVLRPEPPDPEKLPVPPAP-----PSKRHCRSLSVPVDLSRWQ 131
           HL P + G     QP    L P+  +P   PVP  P     P + H    S    LS   
Sbjct: 787 HLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSP-- 844

Query: 132 PVWRPAPSKLWTPIKHRGSGGGGGPQVPHQSPPKRVSSLRFLQAPSASSQC-APAHRPYS 190
              RP  S L              P++  + PP    S R  + P    QC AP   P  
Sbjct: 845 ---RPEESHL-------------SPEL--EKPP---LSPRPEKPPEEPGQCPAPEELPLF 883

Query: 191 PPFFSLALAQDSSRPCAASPQSGSWESDAESLSPCPPQRRFSLSPSLGPQASRFLP---- 246
           PP    +L+     P  + P         E L P  P    SLSP L P      P    
Sbjct: 884 PPPGEPSLSPLLGEPALSEPGEPPLSPLPEEL-PLSPSGEPSLSPQLMPPDPLPPPLSPI 942

Query: 247 -SARSSPASSP----ELPWRPRG 264
            +A + PA SP    E P+  +G
Sbjct: 943 ITAAAPPALSPLGELEYPFGAKG 965



 Score = 35.0 bits (79), Expect = 0.12
 Identities = 66/270 (24%), Positives = 94/270 (34%), Gaps = 69/270 (25%)

Query: 77   HLRPPSRGNSPKEQPFSQ--VLRPEPPDPEKLPVPPAPPSKRHCRSLSVPVDLSRWQPVW 134
            H  PP    +P+ QP +    L+P  P  + L VP +P       S          +P+ 
Sbjct: 2227 HTTPPG---TPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKAS----------EPLL 2273

Query: 135  RPAP---SKLWTPIKHRGSGGGGGPQVPHQSPPKRVSSLRFLQAPSASSQCAPAHRPYSP 191
             P P   S+    +K    G       P   PP    +L F+ +PS+ +         +P
Sbjct: 2274 SPPPFGESRKALEVKKEELGASS----PSYGPP----NLGFVDSPSSGTHLGGLELK-TP 2324

Query: 192  PFFSLALAQDSSRPCAASPQSGSWESDAESLSPCPPQRRFSLSPSLGPQASRFLPSARSS 251
              F   L   +S+    SP  G        L P  P    +L+PS       F P + + 
Sbjct: 2325 DVFKAPLTPRASQVEPQSPGLG--------LRPQEPPPAQALAPSPPSHPDIFRPGSYTD 2376

Query: 252  PASSPELPWRPRGLRNLPRSRSQPCDLDARKTGVKRRHEEDPRRLRPSLDFDKMNQKPYS 311
            P + P L  RP+     P      C L              P R  PS  F ++   P S
Sbjct: 2377 PYAQPPLTPRPQ-----PPPPESCCAL--------------PPRSLPSDPFSRVPASPQS 2417

Query: 312  GGLCLQETAREGSSISPPWFMACSPPPLSA 341
                      + SS SP      +P PLSA
Sbjct: 2418 ----------QSSSQSP-----LTPRPLSA 2432



 Score = 31.2 bits (69), Expect = 1.7
 Identities = 67/276 (24%), Positives = 91/276 (32%), Gaps = 33/276 (11%)

Query: 86  SPKEQPFSQVLRPEPPDPEKLPVPPAPPSKRHCRSLSVPVDLSRWQPVWRPAPSKLWTPI 145
           S  EQ      R  PP+P   P          C+       ++  QP     P  L    
Sbjct: 360 SVAEQHTPVCSRFSPPEPGDTPTDEPDALYVACQGQPKGGHVTSMQP---KEPGPLQCEA 416

Query: 146 KHRGSGGGGGPQVPHQSPPKRVSSLRFLQAPSASSQCAPAHR-PYSPPFFSLALAQDSSR 204
           K  G  G    Q+  Q        +  L  P  S    P    P SPP  +  L+     
Sbjct: 417 KPLGKAG---VQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEE 473

Query: 205 -PCAASPQSGSWESDAESLSPCPPQRRFSLSPSLGPQASRFLPSARSSPASSPELPWRPR 263
            P +  P++       E     PP     LSP   P++S F P    SP S PE      
Sbjct: 474 LPASPLPEALHLSRPLEESPLSPPPEESPLSPP--PESSPFSP-LEESPLSPPE------ 524

Query: 264 GLRNLPRSRSQPCDLDARKTGVKRRHEEDPRRLRPSLDFDKMNQKPYSGGLCLQETAREG 323
                    S P    A +T +    E  P  L P  +   ++  P            E 
Sbjct: 525 --------ESPPSP--ALETPLSPPPEASP--LSPPFEESPLSPPPEE---LPTSPPPEA 569

Query: 324 SSISPPWFMA-CSPPPLSASCSPTGGSSQVLSESEE 358
           S +SPP   +  SPPP  +  SP   +S++    EE
Sbjct: 570 SRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEE 605


>gi|171543895 ataxin 2 [Homo sapiens]
          Length = 1313

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 72/307 (23%), Positives = 113/307 (36%), Gaps = 62/307 (20%)

Query: 36  NCGNSFQLVSEGASWRGLPHCSCAEFQDSLNFSYHPSGLSLHLRPPSRGNSPKEQPFSQV 95
           N G+  ++V+ G  W     C     +    +   P+ L      P R  +P   P    
Sbjct: 538 NSGSDQRVVNGGVPWPS--PCPSPSSRPPSRYQSGPNSL------PPRAATPTRPPSRPP 589

Query: 96  LRPE-PPDPEKLPVPPAPPSKRHCRSLSVPVDLSRWQPVWRPAPSKLWTPIKHRGSGGGG 154
            RP  PP        PAP S       ++P  +S   P  R +P     P  HR S G G
Sbjct: 590 SRPSRPPSHPSAHGSPAPVS-------TMPKRMSSEGPP-RMSPKAQRHPRNHRVSAGRG 641

Query: 155 GPQ-----VPHQSPPKRVSSLRFLQAPSASSQCA----------PAHRPYSPPFFSLALA 199
                   V H  P +  +      +PS  +  +            HRP SP   S+   
Sbjct: 642 SISSGLEFVSHNPPSEAATPPVARTSPSGGTWSSVVSGVPRLSPKTHRPRSPRQNSIG-- 699

Query: 200 QDSSRPCAASPQSGSWESDAESL-------SPCPPQRRFSLSPSLGPQASRFLPSARSSP 252
              S P  ASPQ+G   ++A ++       +P  P    +++PS   + SR     ++SP
Sbjct: 700 NTPSGPVLASPQAGIIPTEAVAMPIPAASPTPASPASNRAVTPSSEAKDSRLQDQRQNSP 759

Query: 253 ASSPELPWRPRGLRNLPRSRSQPCDLDARKTGVK------RRHEEDPR------RLRPSL 300
           A + E         N+  + + P    A   G+       R+  +D +      RL+PS 
Sbjct: 760 AGNKE---------NIKPNETSPSFSKAENKGISPVVSEHRKQIDDLKKFKNDFRLQPSS 810

Query: 301 DFDKMNQ 307
             + M+Q
Sbjct: 811 TSESMDQ 817



 Score = 30.8 bits (68), Expect = 2.2
 Identities = 54/231 (23%), Positives = 81/231 (35%), Gaps = 35/231 (15%)

Query: 128 SRWQPVWRPAPSKLWTPIKHRGSGGGGGPQVPHQSPPKRVSSLRFLQAPSASSQCAPAHR 187
           +RW P WR     L  P +  G GGGG    P+ S            AP       P  R
Sbjct: 23  ARW-PGWR----SLQRPARRSGRGGGGAAPGPYPS-----------AAPPPPGPGPPPSR 66

Query: 188 PYSPPFFSLALAQDSSRPCAASPQSGSWESDAESLSPCPPQRRF--SLSPSLGPQASRFL 245
             SPP  S     + +   A  P S         L    P R F   L P   P A    
Sbjct: 67  QSSPPSASDCFGSNGNGGGAFRPGS------RRLLGLGGPPRPFVVLLLPLASPGAPPAA 120

Query: 246 PSARSSPASSPELPWR-----PRGLRNLPRSRSQPC-DLDARKTGVKRRHEEDPRRLRPS 299
           P+ R+SP  +   P R      R     PR   +P           +++ ++  ++ +  
Sbjct: 121 PT-RASPLGARASPPRSGVSLARPAPGCPRPACEPVYGPLTMSLKPQQQQQQQQQQQQQQ 179

Query: 300 LDFDKMNQKPYSGGLCLQETAREGSSISPPWFMACSPPPLSASCSPTGGSS 350
               +  Q+P      +++    G   SP    A +P P S+S S +  ++
Sbjct: 180 QQQQQQQQQPPPAAANVRKPGGSGLLASP----AAAPSPSSSSVSSSSATA 226


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 56/193 (29%), Positives = 76/193 (39%), Gaps = 14/193 (7%)

Query: 86  SPKEQPFSQVLRPEPPDPEKLPVPPAPPSKRHCRSLSVPVDLSRWQPVWRPAPSKLWTPI 145
           +PK    S   R +   P   P  P+P   R  R+    V L R  P  RP P     P 
Sbjct: 141 APKRSALSAGARRDTSGPT--PGTPSPAMARRSRAAGTEVGLPRPAPSARPRP-PTEGPR 197

Query: 146 KHRGSGGGGGPQVPHQSPPKRVSSLRFLQAPSASSQCAPAHRPYSPPFFSLALAQDSSRP 205
           K   S        P  +  +R S+   LQ P++ S  + A      P  S A +  S+R 
Sbjct: 198 KSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSA-----TPLSSPARSGPSARG 252

Query: 206 CAASPQSGSWESDAESLSPCPPQ---RRFSLSPSLGPQASRFLPSARSSPASSPELPWRP 262
              +P   S        +  PPQ    R   +P+LGP +S   P A  SP S+P  P  P
Sbjct: 253 TPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSS--PLATPSP-SAPPSPSAP 309

Query: 263 RGLRNLPRSRSQP 275
             L+ LP   + P
Sbjct: 310 PSLQTLPSPPATP 322



 Score = 42.7 bits (99), Expect = 6e-04
 Identities = 61/242 (25%), Positives = 83/242 (34%), Gaps = 47/242 (19%)

Query: 47  GASWRGLPHCSCAEFQDSLNFSYHPSGLSL----HLRPPSRGNSPKEQPFSQ--VLRPEP 100
           G S RG P       Q        P GL       + PP +  +P   P S   +  P P
Sbjct: 247 GPSARGTPRAPAHPSQPK------PKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSP 300

Query: 101 PDP---------EKLPVPPAPPSKRHCRSLSVPVDLSRWQPVWRPAPSKLWTPIKHRGSG 151
             P         + LP PPA P  +   SL  P   +    +  P  S L TP       
Sbjct: 301 SAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPA 360

Query: 152 GG----GGPQVPHQSPP-----------KRVSSLRFLQAPSASSQCAPAHRPYSPPFFSL 196
                   P  P  SPP               ++  LQAP +     P   P+SPP  S 
Sbjct: 361 LALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPP-ASP 419

Query: 197 ALAQDSSRPCAASPQSGSWESDAESLSPCPPQRRFSLSPSLGPQASRFLPSARSSPASSP 256
            ++  ++ P  A P   S  +    + P PP      SP + P A+   P     P ++P
Sbjct: 420 PVSPSATPPSQAPP---SLAAPPLQVPPSPP-----ASPPMSPSATP--PPQAPPPLAAP 469

Query: 257 EL 258
            L
Sbjct: 470 PL 471



 Score = 35.0 bits (79), Expect = 0.12
 Identities = 43/173 (24%), Positives = 60/173 (34%), Gaps = 30/173 (17%)

Query: 80  PPSRGNSPKEQPFSQVLRPEPPDPEKLPVPPAPPSKRHCRSLSVPVDLSRWQPVWRPAPS 139
           PP +   P   P  Q+ +P P  P  L  PP        ++L  P      Q  + P+ S
Sbjct: 458 PPPQAPPPLAAPPLQLAKPPPQAPPALATPP-------LQALPSPPASFPGQAPFSPSAS 510

Query: 140 KLWTPIKHRGSGGGGGPQVPHQSPPKRVSSLRFLQAPSASSQCAPAHRPYSPPFFSLALA 199
              +P+             P Q+PP  V +   LQ P +         P  PP       
Sbjct: 511 LPMSPL----------ATPPPQAPP--VLAAPLLQVPPSPPASPTLQAPRRPP------- 551

Query: 200 QDSSRPCAASPQSGSWESDAESLSPCPPQRRFSLSPSLGPQASRFLPSARSSP 252
                P   +  SG   + A +  P PP  R   S   GP  +    SA S+P
Sbjct: 552 ----TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTP 600


>gi|61966919 hypothetical protein LOC442444 [Homo sapiens]
          Length = 1035

 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 67/243 (27%), Positives = 87/243 (35%), Gaps = 30/243 (12%)

Query: 75  SLHLRPPSRGNS-----PKEQPFSQVLRPEPPDPEKLPVPPAPPSKR--HCRSLSVPVDL 127
           SLHL PP  G S     P E+  S  LRPEPPD     + P PP  R  H R       +
Sbjct: 461 SLHLEPPETGVSHLCPEPPEKDVSH-LRPEPPDTGVSHLCPEPPKTRVSHLRPEPSETGV 519

Query: 128 SRWQPVWRPAPSKLWTPIKHRGSGGGGGPQVPHQSPPKRVSSLRFLQAPSASSQCAPAHR 187
           S      RP P K+     H+         +  + P   VS LR    P        + R
Sbjct: 520 SH----LRPEPPKILVSSLHQAPPESSVSHLRPEPPETGVSHLR----PEPPKTRMYSLR 571

Query: 188 PYSPPFFSLALAQDSSRPCAASPQSGSWESDAESLSPCPPQRRFS----LSPSLGPQASR 243
           P  P      L  +  +   +S      E+    L P PP+ R S      P  G    R
Sbjct: 572 PEPPDTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSHLR 631

Query: 244 FLPSARSSPASSPELPWRPRGLRNL----PRSRSQPCDLDARKTGVKRRHEEDPR----R 295
             P      +  PE P    G+ +L    P++R      +  +TGV     E P      
Sbjct: 632 PEPPKTRMYSLRPEPP--NTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSH 689

Query: 296 LRP 298
           LRP
Sbjct: 690 LRP 692



 Score = 34.7 bits (78), Expect = 0.15
 Identities = 63/243 (25%), Positives = 89/243 (36%), Gaps = 22/243 (9%)

Query: 96  LRPEPPDPEKLPVPPAPPSKRHCRSLSVPVDLSRWQPVWRPAPSKLWTPIKHRGSGGGGG 155
           LRPEPP+     + P PP K    SL +    +    +    P K  + ++      G  
Sbjct: 438 LRPEPPETGVSHLRPEPP-KTRVSSLHLEPPETGVSHLCPEPPEKDVSHLRPEPPDTGVS 496

Query: 156 PQVPHQSPPKRVSSLRFLQAPSASSQCAPAHRPYSPPFFSLALAQDSSRPCAASPQSGSW 215
              P + P  RVS LR    P  S       RP  P     +L Q       +  +    
Sbjct: 497 HLCP-EPPKTRVSHLR----PEPSETGVSHLRPEPPKILVSSLHQAPPESSVSHLRPEPP 551

Query: 216 ESDAESLSPCPPQ-RRFSLSPS-LGPQASRFLPSARSSPASS--PELPWRPRGLRNL--- 268
           E+    L P PP+ R +SL P       S   P    +  SS  PE P    G+ +L   
Sbjct: 552 ETGVSHLRPEPPKTRMYSLRPEPPDTGVSHLCPEPPKTRVSSLPPEPP--ETGVSHLCPE 609

Query: 269 -PRSRSQPCDLDARKTGVKRRHEEDPRRLRPSLDFDKMNQKPYSG--GLCLQETAREGSS 325
            P +R      +  +TGV     E P+    SL      + P +G   LC +      SS
Sbjct: 610 PPETRVSHLRPEPPETGVSHLRPEPPKTRMYSL----RPEPPNTGVSHLCPEPPKTRVSS 665

Query: 326 ISP 328
           + P
Sbjct: 666 LPP 668



 Score = 33.9 bits (76), Expect = 0.26
 Identities = 72/276 (26%), Positives = 100/276 (36%), Gaps = 50/276 (18%)

Query: 79  RPPSRGNS--PKEQPFSQV--LRPEPPDPEKLPVPPAPPSKRHCRSLSVPVDLSRWQPVW 134
           RPP    S  P E P + V  LRPEPP+     + P PP K    SL +    +    + 
Sbjct: 189 RPPETRVSCLPPEPPKTPVSSLRPEPPETGVSHLRPQPP-KTQVSSLHLEPPETGVSHL- 246

Query: 135 RPAPSKLWTPIKHRGSGGGGGPQVPHQSPPKRVSSLRFLQAPSAS-SQCAP-------AH 186
           RP P K  T +              H  PP+   S  +L+ P    S   P       +H
Sbjct: 247 RPEPPK--TQVSSL-----------HLEPPETGVSHLYLEPPGTGVSHLCPEPPKTRVSH 293

Query: 187 RPYSPP---FFSLALAQDSSRPCAASPQSGSWESDAESLSPCPPQRRFSLSPSLGPQ--- 240
               PP      L L    SR     P+    E+    L P PP+   +L  SL P+   
Sbjct: 294 LHREPPETGVPDLCLEPPKSRVSHLRPEPS--ETGVSHLHPEPPK---TLVSSLHPEPPE 348

Query: 241 --ASRFLPSARSSPASSPELPWRPRGLRNL----PRSRSQPCDLDARKTGVKRRHEEDPR 294
              S   P    +  S         G+ +L    P++R  P   +  K GV     E P+
Sbjct: 349 TGVSHLCPEPPETRVSPLRQLPPEAGVSHLCPEPPKTRVPPLRPETPKNGVSPLFPEPPK 408

Query: 295 RLRPSLDFDKMNQKPYSG--GLCLQETAREGSSISP 328
               +L     ++ P  G   LCL+     GS + P
Sbjct: 409 TRISNL----RSEPPKIGVSHLCLEPPKTRGSHLRP 440



 Score = 30.8 bits (68), Expect = 2.2
 Identities = 41/121 (33%), Positives = 46/121 (38%), Gaps = 33/121 (27%)

Query: 75  SLHLRPPSRGNS-----PKEQPFSQVLRPEPPDPEKLPVPPAPPSKR--HCRSLSVPVDL 127
           SLH  PP    S     P E   S  LRPEPP P    + P P   R  H R       +
Sbjct: 713 SLHAEPPESRVSHLCPEPPETGVSH-LRPEPPKPRVSSLRPEPLETRVSHLRPEPPETGV 771

Query: 128 SRWQP-VWRPAPSKLWTPIKHRGSGGGGGPQVPHQSPPK--RVSSLRFLQAPS---ASSQ 181
           S   P + +P  S L                  H  PPK  RVSSLR L+ P     SS 
Sbjct: 772 SHLHPELPKPRVSSL------------------HLEPPKTRRVSSLR-LEPPKTGRVSSL 812

Query: 182 C 182
           C
Sbjct: 813 C 813


>gi|95147559 ankyrin repeat domain 43 [Homo sapiens]
          Length = 549

 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 52/188 (27%), Positives = 71/188 (37%), Gaps = 25/188 (13%)

Query: 97  RPEPPDPEKLPVPPAPPSKRHCRSLSVPVDLSRWQPVWRPAPSKLWTPIKHRGSGGGGGP 156
           +P PP+PE  P  P   + +  +  S  +  S   P    AP  +  P      G  G P
Sbjct: 82  KPRPPEPEPAPFGPPGAAAQPSKPTSTVLPRSASAP---GAPPLVRVPRPVEPPGDLGLP 138

Query: 157 QVPHQSPPKRVSSLRFLQAPSASSQCAPAHRPYSPPFFSLALAQDSSRPCA-ASPQSGSW 215
             P  +P            P++     P  R   PP  +L LAQ + RP A A+P     
Sbjct: 139 TEPQDTPG----------GPASEPAQPPGERSADPPLPALELAQATERPSADAAPPP--- 185

Query: 216 ESDAESLSPC--PPQRRFSLSPSLG-PQASRFLPSARSSPASS-----PELPWRPRGLRN 267
            + +E+ SPC  PP        + G PQ    +   R  PA +      E P   R L  
Sbjct: 186 RAPSEAASPCSDPPDAEPGPGAAKGPPQQKPCMLPVRCVPAPATLRLRAEEPGLRRQLSE 245

Query: 268 LPRSRSQP 275
            P  RS P
Sbjct: 246 EPSPRSSP 253


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 51/201 (25%), Positives = 76/201 (37%), Gaps = 18/201 (8%)

Query: 80  PPSRGNSPKEQPFSQVLRPEPPDPEKLPVPP--APP--SKRHCRSLSVPVDLSRWQPVWR 135
           PP     P + P S +  P P  P  +  PP  APP  +    + L  P       P  +
Sbjct: 561 PPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQ 620

Query: 136 PAPSKLWTPIKHRGSGGGGGPQVPHQSPPKRVS---SLRFLQAPSASSQCAPAHRPYSPP 192
             P     P++   S     P  P  +P  +     ++  LQAP +     P   P+SPP
Sbjct: 621 APPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPP 680

Query: 193 FFSLALAQDSSRPCAASPQSGSWESDAESLSPCPPQRRFSLSPSLGPQASRFLPSARSSP 252
             S  ++  ++ P  A P   S  +    + P PP      SP + P A+   P     P
Sbjct: 681 -ASPPVSPSATPPSQAPP---SLAAPPLQVPPSPP-----ASPPMSPSATP--PPQAPPP 729

Query: 253 ASSPELPWRPRGLRNLPRSRS 273
            ++P L   P    + P S S
Sbjct: 730 LAAPPLQVPPSPPASPPMSPS 750



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 50/180 (27%), Positives = 69/180 (38%), Gaps = 13/180 (7%)

Query: 86  SPKEQPFSQVLRPEPPDPEKLPVPPAPPSKRHCRSLSVPVDLSRWQPVWRPAPSKLWTPI 145
           +PK    S   R +   P   P  P+P   R  R+    V L R  P  RP P     P 
Sbjct: 150 APKRSALSAGARRDTSGPT--PGTPSPAMARRSRAAGTEVGLPRPAPSARPRP-PTEGPR 206

Query: 146 KHRGSGGGGGPQVPHQSPPKRVSSLRFLQAPSASSQCAPAHRPYSPPFFSLALAQDSSRP 205
           K   S        P  +  +R S+   LQ P++ S  + A      P  S A +  S+R 
Sbjct: 207 KSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSA-----TPLSSPARSGPSARG 261

Query: 206 CAASPQSGSWESDAESLSPCPPQ---RRFSLSPSLGPQASRFLPSARSSPASSPELPWRP 262
              +P   S        +  PPQ    R   +P+LGP +S   P A  SP+ +   P  P
Sbjct: 262 TPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSS--PLATPSPSGTKARPVPP 319



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 50/198 (25%), Positives = 71/198 (35%), Gaps = 39/198 (19%)

Query: 81  PSRGNSPKEQPFSQVLRPEPPDP------EKLPVPPAPPSKRHCRSLSVPVDLSRWQPVW 134
           P     P   P +  L   PP P      + LP PPA P  +   S++ P       P+ 
Sbjct: 326 PLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTP-------PMQ 378

Query: 135 RPAPSKLWTPIKHRGSGGGGGPQVPH-------QSPPKRVSSLRFLQAPSASSQCAPAHR 187
            P   +   PI           QVPH       Q+PP  ++        S  S    A  
Sbjct: 379 APPSLQTIPPI-----------QVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATH 427

Query: 188 PY--SPPFFSLALAQDSSRPCAASPQSGSWESDAESLSPCPPQRRFSLSPSLGPQASRF- 244
            +    P  + A     SRP +  P S   +  A    P  P  + SLSP++ P +S   
Sbjct: 428 SFLTMSPRQTQASLTSPSRPASTPPDSPPLQ--APLSLPASPPLQTSLSPAVSPLSSPLT 485

Query: 245 ---LPSARSSPASSPELP 259
              L +  S  + SP+ P
Sbjct: 486 IHPLQALSSLASHSPQAP 503



 Score = 34.7 bits (78), Expect = 0.15
 Identities = 62/238 (26%), Positives = 85/238 (35%), Gaps = 53/238 (22%)

Query: 47  GASWRGLPHCSCAEFQDSLNFSYHPSGLSL----HLRPPSRGNSPKEQPFSQ--VLRPEP 100
           G S RG P       Q        P GL       + PP +  +P   P S   +  P P
Sbjct: 256 GPSARGTPRAPAHPSQPK------PKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSP 309

Query: 101 PDPEKLPVPPA-----------PPSKRHCRSLSVPVDLSRWQPVWRPAPSKLWTPIKHRG 149
              +  PVPP            PPS      L+ P+ L+   P   P+   L +P     
Sbjct: 310 SGTKARPVPPPDNAATPLPATLPPSP----PLATPLPLAPPSPSAPPSLQTLPSP----- 360

Query: 150 SGGGGGPQVPHQSPPKRVSSLRFLQAPSASSQCAPAHRPYS-------PPFFSLALAQDS 202
                    P Q+PP   +    +QAP +     P   P+S        P   LAL   S
Sbjct: 361 -----PATPPSQAPPSMTTPP--MQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLAL---S 410

Query: 203 SRPCAASPQSGSWESDAESLSPCPPQRRFSLS----PSLGPQASRFLPSARSSPASSP 256
           S     S  S + ++    L+  P Q + SL+    P+  P  S  L +  S PAS P
Sbjct: 411 SLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPP 468



 Score = 33.9 bits (76), Expect = 0.26
 Identities = 44/173 (25%), Positives = 60/173 (34%), Gaps = 33/173 (19%)

Query: 80  PPSRGNSPKEQPFSQVLRPEPPDPEKLPVPPAPPSKRHCRSLSVPVDLSRWQPVWRPAPS 139
           PPS    P   P S + +P P  P  L  PP        ++L  P      Q  + P+ S
Sbjct: 769 PPS---PPASLPMSPLAKPPPQAPPALATPP-------LQALPSPPASFPGQAPFSPSAS 818

Query: 140 KLWTPIKHRGSGGGGGPQVPHQSPPKRVSSLRFLQAPSASSQCAPAHRPYSPPFFSLALA 199
              +P+             P Q+PP  V +   LQ P +         P  PP       
Sbjct: 819 LPMSPL----------ATPPPQAPP--VLAAPLLQVPPSPPASPTLQAPRRPP------- 859

Query: 200 QDSSRPCAASPQSGSWESDAESLSPCPPQRRFSLSPSLGPQASRFLPSARSSP 252
                P   +  SG   + A +  P PP  R   S   GP  +    SA S+P
Sbjct: 860 ----TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTP 908



 Score = 29.6 bits (65), Expect = 4.9
 Identities = 49/196 (25%), Positives = 67/196 (34%), Gaps = 45/196 (22%)

Query: 80  PPSRGNSPKEQPFSQVLRPEPPDPEKLPV---PPAPPSKRHCRSLSVPVDLSRWQPVWRP 136
           PP +   P   P  QV    P  P   P    PP  P       L VP           P
Sbjct: 722 PPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPS---------P 772

Query: 137 APSKLWTPIKHRGSGGGGGPQVPHQSPPKRVS-SLRFLQAPSASSQCAPAHRPYSP---- 191
             S   +P+           + P Q+PP   +  L+ L +P AS    P   P+SP    
Sbjct: 773 PASLPMSPL----------AKPPPQAPPALATPPLQALPSPPAS---FPGQAPFSPSASL 819

Query: 192 PFFSLALAQDSSRPCAAS---------PQSGSWESDAESLSPCP------PQRRFSLSPS 236
           P   LA     + P  A+         P S + ++     +P P      P+   +L+P 
Sbjct: 820 PMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPG 879

Query: 237 LGPQASRFLPSARSSP 252
             P  SR   S  S P
Sbjct: 880 PPPPPSRSPSSTLSGP 895


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 69/291 (23%), Positives = 92/291 (31%), Gaps = 45/291 (15%)

Query: 71   PSGLSLHLRPPSRGNSPKEQPFSQVLRPEPPDPEKLPVPPA--PPSKRHCRSLSVPVDLS 128
            P G+     P      P   P S    P  P P+  P PPA  PPS +   +        
Sbjct: 927  PKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPA-------- 978

Query: 129  RWQPVWRPAPSKLWTPIKHRGSGGGGGPQVPHQSPPKRVSSLRFLQAPSASSQCAPAHRP 188
                   P+P    TP         GGP  P         S +    P A +  +P   P
Sbjct: 979  ------TPSPKGAPTPPAATPPSPKGGPATP---------SPKGAPTPPAVTPPSPKGSP 1023

Query: 189  YSPPFFSLALAQDSSRPCAASPQSGSWESDAESLSPCPPQRRFSLSPSLGPQASRFLPSA 248
             + PF      + +S P AA+P S      A  L    P    +  PS  P+     PS 
Sbjct: 1024 AATPF-----PKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPS--PKGGPATPSL 1076

Query: 249  RSSPASSPELPWRPRGLRNLPRSRSQPCDLDARKTGVKRRHEEDPRRLRPSLDFDKMNQK 308
            + +P      P  P+G    P  +  P    A     K      P +  P+         
Sbjct: 1077 KGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTT--PAATPP 1134

Query: 309  PYSGGLCL-----QETAREGSSISPPWFMACSPP------PLSASCSPTGG 348
               GGL         T    +  SP   +A  PP      P +   SP GG
Sbjct: 1135 SPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGG 1185



 Score = 38.9 bits (89), Expect = 0.008
 Identities = 47/184 (25%), Positives = 64/184 (34%), Gaps = 31/184 (16%)

Query: 80   PPSRGNSPKEQPFSQVLRPEPPDPEKLPVPPA--PPSKRHCRSLSVPVDLSRWQPVWRPA 137
            P     +P   P S    P  P P+  P PPA  PPS +    L+ P       P     
Sbjct: 1237 PKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLK--GGLATPPHKGAPNPAVVTP 1294

Query: 138  PSKLWTPIKHRGSGGGGGPQVPHQSPPKRVSSLRFLQAPSASSQCAPAHRPYSPPFFSLA 197
            PS           GG      P  SPPK   +      P A++  +P   P +PP     
Sbjct: 1295 PSP---------KGG------PATSPPKGAPT------PPAATPPSPKGSPGTPP----- 1328

Query: 198  LAQDSSRPCAASPQSGSWESDAESLSPCPPQRRFSLSPSLGPQASRFLPSARSSPASSPE 257
              + +  P A +P S        + +P       + S   GP      PS +  PA +P 
Sbjct: 1329 -PKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPP 1387

Query: 258  LPWR 261
             P R
Sbjct: 1388 SPKR 1391



 Score = 38.5 bits (88), Expect = 0.011
 Identities = 56/206 (27%), Positives = 76/206 (36%), Gaps = 16/206 (7%)

Query: 71   PSGLSLHLRPPSRGNSPKEQPFSQVLRPEPPDPEKLPVPPA--PPSKRHCRSLSVPVDLS 128
            P G      P      P   P S    P  P P+  P PPA  PPS +   +L      S
Sbjct: 1297 PKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSS 1356

Query: 129  RWQPVWRPAPSKLWTPIKHRGSGGGGGPQVPHQSPPKRVSSLRFLQAPSASSQ-CAPAHR 187
            +  P   P+  +  TP     S  GG    P  +PP   S  R    PS      +PA  
Sbjct: 1357 KGGPT-TPSSKEGPTPPAATPSHKGG----PAMTPP---SPKRGPAIPSPKGDPTSPAVI 1408

Query: 188  PYSPPFFSLALAQDSSRPCAASPQSGSWESDAESLSPCPPQRRFSLSPSLGPQASRFLPS 247
            P SP     A A   +R  AA+P  G     A  ++P   ++  + S   G  A+     
Sbjct: 1409 PLSP---KKAPATPVTREGAATPSKGDLTPPA--VTPVSLKKAPATSAPKGGPATPSSKG 1463

Query: 248  ARSSPASSPELPWRPRGLRNLPRSRS 273
              + PA +P  P  P   + +  S S
Sbjct: 1464 DPTLPAVTPPSPKEPPAPKQVATSSS 1489



 Score = 36.6 bits (83), Expect = 0.040
 Identities = 64/272 (23%), Positives = 92/272 (33%), Gaps = 61/272 (22%)

Query: 71   PSGLSLHLRPPSRGNSPKEQPFSQVLRPEPPDPEKLPVPPAPPSKRHCRSLSVPVDLSRW 130
            PS   L + P     SPKE P    + P  P PEK P  PAP         S PV  S  
Sbjct: 1594 PSPKELLIPPAVTSPSPKEAPTPPAVTP--PSPEKGPATPAPKG----TPTSPPVTPSS- 1646

Query: 131  QPVWRPAPSKLWTPIKHRGSGGGGGPQVPHQSPPKRVSSLRFLQAPSASSQCAPAHRPYS 190
                + +P+   +P       G   PQ     P K+         P+A  +   A  P S
Sbjct: 1647 ---LKDSPT---SPASVTCKMGATVPQASKGLPAKK--------GPTALKEVLVAPAPES 1692

Query: 191  PPFFSLALAQDSSRPCAASPQSGSWESDAESLSPCPPQRRFSLSPSLGPQASRFLPSAR- 249
             P          + P    PQ+    + +  + P P  +  S  P      +  LP  + 
Sbjct: 1693 TPII--------TAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKD 1744

Query: 250  -SSPASSPELPWRPRGLRNLPRSR-SQPCDLDARKTGVKRRHEEDPRRLRPSLDFDKMNQ 307
             S  A   +    P+G    P S+ S P    A                     F+K+  
Sbjct: 1745 SSKTAKGKDASHSPKGPLAPPESKASTPLTAAA---------------------FEKVLP 1783

Query: 308  KPYSGGLCLQETAREGSSISPPWFMACSPPPL 339
            KP        E+A   ++ SPP  +  +P P+
Sbjct: 1784 KP--------ESASVSAAPSPPVSLPLAPSPV 1807



 Score = 36.2 bits (82), Expect = 0.052
 Identities = 43/182 (23%), Positives = 68/182 (37%), Gaps = 32/182 (17%)

Query: 98   PEPPDPEKLPVPPAPPSKRHCRSLSVPVDLSRWQPVWRPAPSKLWTPIKHRGSGGGGGPQ 157
            P PP P+  P P A  +    + +++P       P   P PS +  P    G        
Sbjct: 856  PTPPSPKGAPTPSA-VTPLSPKGVTLP-------PKETPTPSVVNLPFPKEG-------- 899

Query: 158  VPHQSPPKRVSSLRFLQAPSASSQCAPAHR--PYSPPFFSLALAQDSSRPCAASPQS--G 213
             P    PK+  +L    +    ++  PA +  P SP        + +  P AA+P S  G
Sbjct: 900  -PATPAPKQAPALSMTSSSPKKARATPAPKGIPASPS------PKGAPTPPAATPPSPKG 952

Query: 214  SWESDAESLSPCPPQRRFSLSPSLGPQASRFLPSARSSPASSPELPWRPRGLRNLPRSRS 273
               + +   +P PP    +  PS  P+     PS + +P      P  P+G    P  + 
Sbjct: 953  GPATPSPKWAPTPPA---ATPPS--PKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKG 1007

Query: 274  QP 275
             P
Sbjct: 1008 AP 1009


>gi|18079216 CASK interacting protein 1 [Homo sapiens]
          Length = 1431

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 59/211 (27%), Positives = 83/211 (39%), Gaps = 41/211 (19%)

Query: 69   YHPSGLSLHLRPPSRGNSPKEQPFSQVLRPEPPDPEKLP-----VPPAPPSKRHCRSLSV 123
            YH    ++  RP S    P E P      P PP  E  P     +PP PP +   R  + 
Sbjct: 1170 YHNGTGTVRRRPASEQAGPPELP------PPPPPAEPPPTDLAHLPPLPPPEGEARKPAK 1223

Query: 124  PVDLSR---WQPVWR----PAPSKLWTPIKHRGS-----GGGGGPQV-----PHQSPPKR 166
            P    +    QPV +    P P+    P+   GS       G  P V     P  + PK 
Sbjct: 1224 PPVSPKPVLTQPVPKLQGSPTPTSKKVPLPGPGSPEVKRAHGTPPPVSPKPPPPPTAPKP 1283

Query: 167  VSSLRFLQAPSASSQCAPAHRPYSPPFFSLALAQDSSRPCAASPQSGSWESDAESLSPCP 226
            V ++  L  PS S+  +PA  P   P  +LA      +P    P  G+  S A+  SP  
Sbjct: 1284 VKAVAGL--PSGSAGPSPAPSPARQPPAALA------KPPGTPPSLGA--SPAKPPSPGA 1333

Query: 227  PQRRFSLSPSLGPQASRFLPSARSSPASSPE 257
            P       P   P+A+    +A ++P + PE
Sbjct: 1334 PALHVPAKP---PRAAAAAAAAAAAPPAPPE 1361



 Score = 36.6 bits (83), Expect = 0.040
 Identities = 36/148 (24%), Positives = 50/148 (33%), Gaps = 9/148 (6%)

Query: 79   RPPSRGNSPKEQPFSQVLRPEPPDPEKLPVP-PAPPSKRHCRSLSVPVDLSRWQPVWRPA 137
            +PP        QP  ++     P  +K+P+P P  P  +       PV      P   P 
Sbjct: 1223 KPPVSPKPVLTQPVPKLQGSPTPTSKKVPLPGPGSPEVKRAHGTPPPVSPKPPPPPTAPK 1282

Query: 138  PSKLWTPIKHRGSGGGGGPQVPHQ------SPPKRVSSLRFLQAPSASSQCAPAHRPYSP 191
            P K    +    +G    P    Q       PP    SL    A   S      H P  P
Sbjct: 1283 PVKAVAGLPSGSAGPSPAPSPARQPPAALAKPPGTPPSLGASPAKPPSPGAPALHVPAKP 1342

Query: 192  PFFSLALAQDSSRPCAASPQSGSWESDA 219
            P  + A A  ++ P A  P  G+   D+
Sbjct: 1343 PRAAAAAAAAAAAPPA--PPEGASPGDS 1368


>gi|239754993 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 221

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 44/120 (36%), Positives = 53/120 (44%), Gaps = 26/120 (21%)

Query: 160 HQSPPKRVSSLRFLQAPSASS--QCAPAHRPYSPPFFSLALAQDSSRPCAASPQSGSWES 217
           HQSP         + +PSAS    CAPA   + PP   LALA  S R   A P       
Sbjct: 118 HQSPLA-------IPSPSASPPPSCAPAPHSHPPPI-GLALACKSRRWPRAQPSR----- 164

Query: 218 DAESLSPCPP-----QRRFSLSPSLGPQASRFLPSARSSPASSPE--LPWRPRGLRNLPR 270
               +SP PP     Q  + L+  LGP+A +   S  SSP S P   LP R R    LP+
Sbjct: 165 ----MSPGPPLWERRQSYWPLTRPLGPRARQAFESTCSSPESRPRPCLPHRSRPQSTLPQ 220


>gi|24797153 faciogenital dysplasia protein [Homo sapiens]
          Length = 961

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 86/326 (26%), Positives = 108/326 (33%), Gaps = 71/326 (21%)

Query: 51  RGLPHCSCAEFQDSLNFSYHPSGLSLHLRPP-SRGNSPKEQPFS----QVLRPEPPDPEK 105
           R LP     +   +L FSYH  G     RP   +GN    +  S    Q L P P  P++
Sbjct: 75  RVLPCGPSPQHHRALRFSYHLEGSQP--RPGLHQGNRILVKSLSLDPGQSLEPHPEGPQR 132

Query: 106 LPVPPAPPSKRHCRSLSVPVDLSRWQPVWRPAPSKLWTPIKHRGSGGGGGPQVPHQSPPK 165
           L   P PP++                P  RP+P K            G  PQV    PPK
Sbjct: 133 LRSDPGPPTE---------------TPSQRPSPLK---------RAPGPKPQV----PPK 164

Query: 166 RVSSLRFLQAPSASSQCAPAHRPYSPPF-FSLALAQDSSRPCAASPQSGSWESDAESLSP 224
                 +LQ P       P   P S P      +A+  +    ASP S +  S  E    
Sbjct: 165 P----SYLQMPRMPPPLEPIPPPPSRPLPADPRVAKGLAPRAEASPSSAAVSSLIEKFER 220

Query: 225 CP---PQRRFSLSPSLGPQASRFLPSARSSPASSPELPWRPRGLRNLPRSRSQPCDLDAR 281
            P      R    PS GP     LP     P S P +P  P G  +       P   D  
Sbjct: 221 EPVIVASDRPVPGPSPGPPEPVMLP----QPTSQPPVPQLPEGEASRCLFLLAPGPRDGE 276

Query: 282 KTGVKRRHEEDPRRLRPSLDFDKMNQKPYSGGLCLQETAREGSSISPPWFMACSPPPLSA 341
           K          P R       D ++    S   C        S   PP    C  PP  A
Sbjct: 277 KV---------PNR---DSGIDSISSPSNSEETCFV------SDDGPPSHSLCPGPPALA 318

Query: 342 SCSPT------GGSSQVLSESEEEEE 361
           S           GS +V S+ EEE++
Sbjct: 319 SVPVALADPHRPGSQEVDSDLEEEDD 344


>gi|237757310 synaptojanin 1 isoform a [Homo sapiens]
          Length = 1612

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 72/278 (25%), Positives = 97/278 (34%), Gaps = 84/278 (30%)

Query: 80   PPSRGNSPKE-QPFSQV-----------LRPEPPDPEKLPVPPAPPSKRHCRSLSVPVDL 127
            PPS  +SP + QP + +            RP PP P   P  PAPP +            
Sbjct: 1117 PPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQR------------ 1164

Query: 128  SRWQPVWRPAPSKLWTPIKHRGSGGGGGPQVPHQSPPKRVSSLRFLQAPSA--------- 178
                    P PS   +P   R   GG G      +PP    + R ++AP +         
Sbjct: 1165 -------PPPPSGARSPAPTRKEFGGIG------APPSPGVARREMEAPKSPGTTRKDNI 1211

Query: 179  -SSQCAP-------------AHRPYSPPFFSLALAQDSSRPCAA---SPQSGSWESDAES 221
              SQ +P               RP  PP   +  A  S    +A   +P+S S  S+   
Sbjct: 1212 GRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSK 1271

Query: 222  LS-----PCPPQRRFSLSPSLGPQASR----FLPSARSSPASS--------PELPWRPRG 264
             S     P  PQ  F    SL P A R     +P A   P S         P+ P R R 
Sbjct: 1272 GSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRS 1331

Query: 265  LRNLP-RSRSQPCDLDARKTGVKRRHEEDPRRLRPSLD 301
              +LP  + SQP     +  G+     E P ++ P  D
Sbjct: 1332 SHSLPSEASSQP---QVKTNGISDGKRESPLKIDPFED 1366


>gi|58530845 zyxin [Homo sapiens]
          Length = 572

 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 47/203 (23%), Positives = 72/203 (35%), Gaps = 33/203 (16%)

Query: 80  PPSRGNSPKEQPFSQVLRPEPPDPEK------LPVPPAPPSKRHCRSLSVPVD------- 126
           PP    S    P  + + P PP P +       P+PP P  +    S+ + +D       
Sbjct: 97  PPPIEESFPPAPLEEEIFPSPPPPPEEEGGPEAPIPPPPQPREKVSSIDLEIDSLSSLLD 156

Query: 127 -LSRWQPVWRPA-----PSKLWTPIKHRGS----GGGGGPQVPHQSPPKRVSSLRFLQAP 176
            +++  P          P  + TP   + S     GG  P  P +SP    SS    Q P
Sbjct: 157 DMTKNDPFKARVSSGYVPPPVATPFSSKSSTKPAAGGTAPLPPWKSPS---SSQPLPQVP 213

Query: 177 SASSQCAPAH---RPYSPPFFSLALAQDSSRPCAASPQSGSWESDAESLSPCPPQRRFSL 233
           + +      H   +P   P   L +   +     A+ Q         + SP P  +   +
Sbjct: 214 APAQSQTQFHVQPQPQPKPQVQLHVQSQTQPVSLANTQPRG----PPASSPAPAPKFSPV 269

Query: 234 SPSLGPQASRFLPSARSSPASSP 256
           +P   P AS+F P A     S P
Sbjct: 270 TPKFTPVASKFSPGAPGGSGSQP 292


>gi|4508047 zyxin [Homo sapiens]
          Length = 572

 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 47/203 (23%), Positives = 72/203 (35%), Gaps = 33/203 (16%)

Query: 80  PPSRGNSPKEQPFSQVLRPEPPDPEK------LPVPPAPPSKRHCRSLSVPVD------- 126
           PP    S    P  + + P PP P +       P+PP P  +    S+ + +D       
Sbjct: 97  PPPIEESFPPAPLEEEIFPSPPPPPEEEGGPEAPIPPPPQPREKVSSIDLEIDSLSSLLD 156

Query: 127 -LSRWQPVWRPA-----PSKLWTPIKHRGS----GGGGGPQVPHQSPPKRVSSLRFLQAP 176
            +++  P          P  + TP   + S     GG  P  P +SP    SS    Q P
Sbjct: 157 DMTKNDPFKARVSSGYVPPPVATPFSSKSSTKPAAGGTAPLPPWKSPS---SSQPLPQVP 213

Query: 177 SASSQCAPAH---RPYSPPFFSLALAQDSSRPCAASPQSGSWESDAESLSPCPPQRRFSL 233
           + +      H   +P   P   L +   +     A+ Q         + SP P  +   +
Sbjct: 214 APAQSQTQFHVQPQPQPKPQVQLHVQSQTQPVSLANTQPRG----PPASSPAPAPKFSPV 269

Query: 234 SPSLGPQASRFLPSARSSPASSP 256
           +P   P AS+F P A     S P
Sbjct: 270 TPKFTPVASKFSPGAPGGSGSQP 292


>gi|40556370 PHD finger protein 15 [Homo sapiens]
          Length = 790

 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 46/161 (28%), Positives = 60/161 (37%), Gaps = 35/161 (21%)

Query: 97  RPEPPDPEKLPVPPAPPSKRHCRSLSVPVDLSRWQPVWRPAPSKLWTPIKHRGSGGGG-G 155
           +P PP P+  P     P K                     AP K W   +  GSG GG G
Sbjct: 605 KPPPPPPQDGPGSRTTPDK---------------------APKKTWG--QDAGSGKGGQG 641

Query: 156 PQVPHQSPPKRVSSLRFLQAPSASSQCAPAHRPYSPPFFSLALAQDSSRPCAASPQSGSW 215
           P  P + PP+R SS   L +  A+  C     P SPP     LA ++    A+       
Sbjct: 642 P--PTRKPPRRTSS--HLPSSPAAGDCPILATPESPP----PLAPETPDEAASVAADSDV 693

Query: 216 ESDAESLSPCPPQRRFSLSPSLGPQASRFLPSARSSPASSP 256
           +    + SP P  R   L P    + +R LP AR      P
Sbjct: 694 QVPGPAASPKPLGR---LRPPRESKVTRRLPGARPDAGMGP 731


>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
           preproprotein [Homo sapiens]
          Length = 331

 Score = 42.7 bits (99), Expect = 6e-04
 Identities = 54/206 (26%), Positives = 70/206 (33%), Gaps = 45/206 (21%)

Query: 80  PPSRGNSPKEQPFSQVLRPEPPDPEKLPVPPAPPSKRHCRSLSVPVDLSRWQPVWRPAPS 139
           PP  GN P+  P     +  PP  +K   P +PP K        P      QP   P P 
Sbjct: 61  PPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKP-----QGPPPQGGNQPQGPPPP- 114

Query: 140 KLWTPIKHRG--SGGGGGPQVP-----HQSPPKRVSSLRFLQAPSASSQCAP---AHRPY 189
               P K +G    GG  PQ P      Q PP +    R  ++P    Q  P    ++P 
Sbjct: 115 ----PGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQ 170

Query: 190 SPPFFSLALAQDSSRPCAASPQSGSWESDAESLSPCPP-----------QRRFSLSPSLG 238
            PP            P    PQ    +   +   P PP           + R S SP   
Sbjct: 171 GPP------------PPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGK 218

Query: 239 PQASRFLPSARSSPASSPELPWRPRG 264
           PQ     P   + P   P  P +P+G
Sbjct: 219 PQGPP--PQGGNQPQGPPPPPGKPQG 242



 Score = 36.6 bits (83), Expect = 0.040
 Identities = 56/211 (26%), Positives = 73/211 (34%), Gaps = 46/211 (21%)

Query: 71  PSGLSLHLRPPSRGNSPKEQPFSQVLRPEPPDPEKLPVPPAPPSKRHCRSLSVPVDLSRW 130
           P G +    PP     P+  P     RP+ P P   P  P PP     RS   P    + 
Sbjct: 102 PQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGP-PPQGDKSRSPRSPPGKPQG 160

Query: 131 -------QPVWRPAPSKLWTPIKHRG--SGGGGGPQVP-----HQSPPKRVSSLRFLQAP 176
                  QP   P P     P K +G    GG  PQ P      Q PP +    R  Q+P
Sbjct: 161 PPPQGGNQPQGPPPP-----PGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSP 215

Query: 177 SASSQCAP---AHRPYSPPFFSLALAQDSSRPCAASPQSGSWESDAESLSPCPPQRRFSL 233
               Q  P    ++P  PP           +P    PQ G+     +   P PP +    
Sbjct: 216 PGKPQGPPPQGGNQPQGPP-------PPPGKPQGPPPQGGN-----KPQGPPPPGK---- 259

Query: 234 SPSLGPQASRFLPSARSSPASSPELPWRPRG 264
                PQ       ++S  A SP  P +P+G
Sbjct: 260 -----PQGPPAQGGSKSQSARSP--PGKPQG 283



 Score = 32.3 bits (72), Expect = 0.76
 Identities = 41/179 (22%), Positives = 57/179 (31%), Gaps = 22/179 (12%)

Query: 71  PSGLSLHLRPPSRGNSPKEQPFSQVLRPEPPDPEKLPVPPAPPSKRHCRSLSV------P 124
           P G +    PP     P+  P     +P+ P P   P  P P   +   S S       P
Sbjct: 163 PQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGP 222

Query: 125 VDLSRWQPVWRPAPSKLWTPIKHRGSGGGGGPQVPHQSPPKRVSSLRFLQAPSASSQCAP 184
                 QP   P P     P K +G    GG +     PP +           + S  +P
Sbjct: 223 PPQGGNQPQGPPPP-----PGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSP 277

Query: 185 AHRPYSPPFFSLALAQDSSRPCAASPQSGSWESDAESLSPCPPQRRFSLSPSLGPQASR 243
             +P  PP       Q+ + P    P +G      ++     PQ      P   PQ  R
Sbjct: 278 PGKPQGPP------QQEGNNPQGPPPPAGGNPQQPQAPPAGQPQ-----GPPRPPQGGR 325


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 52/204 (25%), Positives = 72/204 (35%), Gaps = 34/204 (16%)

Query: 70  HPSGLSLHLRPPSRGNSPKEQPFSQVLRPEPPDPEKLPVPPAPPSKRHCRSLSVPVDLSR 129
           H S L+  L  P         P +      PP  + LP PPA P  +   SL  P   + 
Sbjct: 326 HSSSLTCQLATPL--------PLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQAT 377

Query: 130 WQPVWRPAPSKLWTPIKHRGSGGG----GGPQVPHQSPP-----------KRVSSLRFLQ 174
              +  P  S L TP               P  P  SPP               ++  LQ
Sbjct: 378 HSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQ 437

Query: 175 APSASSQCAPAHRPYSPPFFSLALAQDSSRPCAASPQSGSWESDAESLSPCPPQRRFSLS 234
           AP +     P   P+SPP  S  ++  ++ P  A P   S  +    + P PP      S
Sbjct: 438 APFSPPPSPPVQAPFSPP-ASPPVSPSATPPSQAPP---SLAAPPLQVPPSPP-----AS 488

Query: 235 PSLGPQASRFLPSARSSPASSPEL 258
           P + P A+   P     P ++P L
Sbjct: 489 PPMSPSATP--PPQAPPPLAAPPL 510



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 55/196 (28%), Positives = 76/196 (38%), Gaps = 14/196 (7%)

Query: 86  SPKEQPFSQVLRPEPPDPEKLPVPPAPPSKRHCRSLSVPVDLSRWQPVWRPAPSKLWTPI 145
           +PK    S   R +   P   P  P+P   R  R+    V L R  P  RP P     P 
Sbjct: 150 APKRSALSAGARRDTSGPT--PGTPSPAMARRSRAAGTEVGLPRPAPSARPRP-PTEGPR 206

Query: 146 KHRGSGGGGGPQVPHQSPPKRVSSLRFLQAPSASSQCAPAHRPYSPPFFSLALAQDSSRP 205
           K   S        P  +  +R S+   LQ P++ S  + A      P  S A +  S+R 
Sbjct: 207 KSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSA-----TPLSSPARSGPSARG 261

Query: 206 CAASPQSGSWESDAESLSPCPPQ---RRFSLSPSLGPQASRFLPSARSSPASSPELPWRP 262
              +P   S        +  PPQ    R   +P+LGP +S   P A  SP+++ +    P
Sbjct: 262 TPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSS--PLATPSPSAALQ-SQAP 318

Query: 263 RGLRNLPRSRSQPCDL 278
             L   P S S  C L
Sbjct: 319 PTLPATPHSSSLTCQL 334



 Score = 35.0 bits (79), Expect = 0.12
 Identities = 43/173 (24%), Positives = 60/173 (34%), Gaps = 30/173 (17%)

Query: 80  PPSRGNSPKEQPFSQVLRPEPPDPEKLPVPPAPPSKRHCRSLSVPVDLSRWQPVWRPAPS 139
           PP +   P   P  Q+ +P P  P  L  PP        ++L  P      Q  + P+ S
Sbjct: 497 PPPQAPPPLAAPPLQLAKPPPQAPPALATPP-------LQALPSPPASFPGQAPFSPSAS 549

Query: 140 KLWTPIKHRGSGGGGGPQVPHQSPPKRVSSLRFLQAPSASSQCAPAHRPYSPPFFSLALA 199
              +P+             P Q+PP  V +   LQ P +         P  PP       
Sbjct: 550 LPMSPL----------ATPPPQAPP--VLAAPLLQVPPSPPASPTLQAPRRPP------- 590

Query: 200 QDSSRPCAASPQSGSWESDAESLSPCPPQRRFSLSPSLGPQASRFLPSARSSP 252
                P   +  SG   + A +  P PP  R   S   GP  +    SA S+P
Sbjct: 591 ----TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTP 639


>gi|56118221 amyloid beta (A4) precursor protein-binding, family B,
           member 1 interacting protein [Homo sapiens]
          Length = 666

 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 44/170 (25%), Positives = 57/170 (33%), Gaps = 36/170 (21%)

Query: 98  PEPPDPEKLPVPPAPPSKRHCRSLSVPVDLSRWQPVWRPAPSKLWTPIKHRGSGGGGGPQ 157
           P  P   K  +PP PP +R   +   P                  TP+K +G+GGGG P 
Sbjct: 506 PRAPHAPKSSLPPPPPVRRSSDTSGSPA-----------------TPLKAKGTGGGGLPA 548

Query: 158 VPHQSPPKRVSSLRFLQAPSASSQCAPAHRPYSPPFFSLALAQDSSRPCAASPQSGSWES 217
            P            FL  P           P  PP F          P    P   S+  
Sbjct: 549 PPDD----------FLPPPPPPPPLDDPELPPPPPDFM------EPPPDFVPPPPPSYAG 592

Query: 218 DAESLSPCPPQRRFSLSPSLGPQASRFLPSARSSPASSP---ELPWRPRG 264
            A S  P PP    + +P+  P ++R  P+    P   P   E P  P G
Sbjct: 593 IAGSELPPPPPPPPAPAPAPVPDSARPPPAVAKRPPVPPKRQENPGHPGG 642


>gi|27436917 misshapen/NIK-related kinase isoform 3 [Homo sapiens]
          Length = 1332

 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 55/206 (26%), Positives = 79/206 (38%), Gaps = 32/206 (15%)

Query: 85  NSPKEQPFSQVLRPEPPDPEKLPVPPAPPSKRHCRSLSVPVDLSRWQPVWRPAPSKLWTP 144
           NSP  +       PEPP P+  P PP P              LS+  P+ RP   +    
Sbjct: 534 NSPLAKSKPGSTGPEPPIPQASPGPPGP--------------LSQTPPMQRPVEPQ---E 576

Query: 145 IKHRGSGGGGGPQVPHQSPPKRVSSL-----RFLQAPSASSQCAPA-HRPYSPPFFSLAL 198
             H+       P  P+ +P  R  SL     R L A  AS    PA   P + P    A+
Sbjct: 577 GPHKSLVAHRVPLKPYAAPVPRSQSLQDQPTRNLAAFPASHDPDPAIPAPTATPSARGAV 636

Query: 199 AQDSSRPCA----ASPQSGSWESDAESLSPCPPQRRFSLSPSL---GPQASRFLPSARSS 251
            + +S P +     SP   +W        P  PQR  S++ +L   G   SR   + R+ 
Sbjct: 637 IRQNSDPTSEGPGPSPNPPAWVRPDNEAPPKVPQRTSSIATALNTSGAGGSRPAQAVRAR 696

Query: 252 PASSP--ELPWRPRGLRNLPRSRSQP 275
           P S+   ++  + R  R  P+    P
Sbjct: 697 PRSNSAWQIYLQRRAERGTPKPPGPP 722


>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
            1 [Homo sapiens]
          Length = 1250

 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 62/249 (24%), Positives = 79/249 (31%), Gaps = 58/249 (23%)

Query: 43   LVSEGASWRGLPHCSCAEFQDSLNFSYHPSGLSLHLRPPSRGNSPKEQPFSQVLRPEPPD 102
            +V++ A     P    A+ Q +   SY P        P      PK+Q F     P P  
Sbjct: 797  VVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLS 856

Query: 103  P---------EKLPVPPAPPSKRHCRSLSVPVDLS-----------RWQPVWRPAPSKLW 142
            P          + P PP PP+        VP +++           +WQP   P PS   
Sbjct: 857  PVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPS--- 913

Query: 143  TPIKHRGSGGGGGPQVPHQSPPKRVSSLRFLQAPSASSQCAPAHRPYSPPFFSLALAQDS 202
                            P   PP   SSL F   P +     PA  P  PP  S    +  
Sbjct: 914  ----------------PDFPPPPPESSLVFPPPPPSP---VPAPPPPPPPTASPTPDKSG 954

Query: 203  SRPCAASPQSGSWESDAESLSPCPPQRRFSLSPSLGPQ------------ASRFLPSARS 250
            S     S  S    S      P  PQR  S+  S G +             S+F P A S
Sbjct: 955  SPGKKTSKTS----SPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAES 1010

Query: 251  SPASSPELP 259
               S   LP
Sbjct: 1011 GSPSKETLP 1019



 Score = 36.6 bits (83), Expect = 0.040
 Identities = 36/141 (25%), Positives = 54/141 (38%), Gaps = 32/141 (22%)

Query: 81   PSRGNSPKEQPFSQVLRPEPPDPEKLPVPPAPPSKRHCRSLSVPVDLSRWQPVWRPAPSK 140
            PS    P     S V  P PP P   P PP PP+                     P P K
Sbjct: 912  PSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTA-------------------SPTPDK 952

Query: 141  LWTPIKHRGSGGGGGPQVPHQSPPKRVSSLRFLQAPSASSQCAPAHRP--------YSPP 192
              +P K        G + P  + P+R SS++     S+ ++     RP        ++PP
Sbjct: 953  SGSPGKKTSKTSSPGGKKPPPT-PQRNSSIK----SSSGAEHPEPKRPSVDSLVSKFTPP 1007

Query: 193  FFSLALAQDSSRPCAASPQSG 213
              S + ++++  P AA P+ G
Sbjct: 1008 AESGSPSKETLPPPAAPPKPG 1028



 Score = 31.6 bits (70), Expect = 1.3
 Identities = 45/188 (23%), Positives = 66/188 (35%), Gaps = 23/188 (12%)

Query: 80  PPSRGNSPKEQPFSQVLRPEPPDPEKLPVPPAPPSKRHCRSLSVPVDLSRWQPVWRPAPS 139
           PP      + Q  +QV  P PP P  +P  P PP       +++P           P  +
Sbjct: 743 PPPPLKIHQVQHITQVAPPTPPPPPPIPA-PLPPQAPPKPLVTIPA----------PTST 791

Query: 140 KLWTPIKHRGSGGGGGPQVPHQSPPKRVSSLRFLQAPSASSQCAPAHRPYSPPFFSLALA 199
           K   P+  + +     P VP   P K+  +      P++    +P   P   P  +L   
Sbjct: 792 KTVAPVVTQAAPPTPTPPVP---PAKKQPAF-----PASYIPPSPPTPPVPVPPPTLPKQ 843

Query: 200 QDSSRPCAASPQS--GSWESDAESLSPCPPQRRFSLSPSLGPQASRFLPSARSSPASSPE 257
           Q        SP S   S      S  P PP      S  L P  +   P  +S PA   +
Sbjct: 844 QSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAP--QSPPAVKAK 901

Query: 258 LPWRPRGL 265
             W+P  +
Sbjct: 902 PKWQPSSI 909



 Score = 30.4 bits (67), Expect = 2.9
 Identities = 50/202 (24%), Positives = 69/202 (34%), Gaps = 23/202 (11%)

Query: 90  QPFSQVLRPEPPDPEKLPVPPAPPSKRHCRSLSVPVDLSRWQPVWRPAPSKLWTPIKHRG 149
           QP   +  P PP P   P PP PP      S S P   S       P   K  T  + + 
Sbjct: 623 QPSPPLPPPPPPPPPPPPPPPPPPPP--LPSQSAPSAGSA-----APMFVKYSTITRLQN 675

Query: 150 SGGGGGPQVPHQSPPKRVS-SLRFLQAPSASSQCAPAHRPYSPPFFSLALAQDSSRPCAA 208
           +    G      +PP   S S++       +    P   P  PP    A+AQ    PCA 
Sbjct: 676 ASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAP 735

Query: 209 S-PQSGS------------WESDAESLSPCPPQRRFSLSPSLGPQASRFLPSARSSPASS 255
           S PQ  +                A    P PP     L P   P+    +P+  S+   +
Sbjct: 736 SLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVA 795

Query: 256 PELPWR--PRGLRNLPRSRSQP 275
           P +     P     +P ++ QP
Sbjct: 796 PVVTQAAPPTPTPPVPPAKKQP 817


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.131    0.418 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,843,199
Number of Sequences: 37866
Number of extensions: 1316754
Number of successful extensions: 9137
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 76
Number of HSP's successfully gapped in prelim test: 646
Number of HSP's that attempted gapping in prelim test: 7109
Number of HSP's gapped (non-prelim): 2078
length of query: 392
length of database: 18,247,518
effective HSP length: 104
effective length of query: 288
effective length of database: 14,309,454
effective search space: 4121122752
effective search space used: 4121122752
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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