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Search of human proteins with 7705773
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7705773 SH3-containing protein SH3GLB1 [Homo sapiens]
(365 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7705773 SH3-containing protein SH3GLB1 [Homo sapiens] 717 0.0
gi|9910352 SH3-domain GRB2-like endophilin B2 [Homo sapiens] 466 e-131
gi|4506929 SH3-domain GRB2-like 1 [Homo sapiens] 126 3e-29
gi|223468657 SH3-domain GRB2-like 3 [Homo sapiens] 112 5e-25
gi|4506931 SH3-domain GRB2-like 2 [Homo sapiens] 112 7e-25
gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens] 51 2e-06
gi|242117953 SH3 domain-containing protein C1orf113 isoform 1 [H... 46 6e-05
gi|242117948 SH3 domain-containing protein C1orf113 isoform 2 [H... 46 6e-05
gi|193083145 SH3 domain containing 19 isoform c [Homo sapiens] 45 1e-04
gi|193083143 SH3 domain containing 19 isoform b [Homo sapiens] 45 1e-04
gi|193083141 SH3 domain containing 19 isoform a [Homo sapiens] 45 1e-04
gi|20149528 proline-serine-threonine phosphatase interacting pro... 44 3e-04
gi|47087157 nebulette non-muscle isoform [Homo sapiens] 43 4e-04
gi|23397574 sorting nexin 33 [Homo sapiens] 43 5e-04
gi|5453758 nebulette sarcomeric isoform [Homo sapiens] 42 7e-04
gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens] 41 0.002
gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens] 41 0.002
gi|50843948 Rho GTPase activating protein 10 [Homo sapiens] 41 0.002
gi|197304715 vav 2 guanine nucleotide exchange factor isoform 1 ... 40 0.004
gi|40549448 vav 2 guanine nucleotide exchange factor isoform 2 [... 40 0.004
gi|4507249 signal transducing adaptor molecule 1 [Homo sapiens] 39 0.006
gi|78000171 sorbin and SH3 domain containing 1 isoform 7 [Homo s... 39 0.006
gi|78000169 sorbin and SH3 domain containing 1 isoform 6 [Homo s... 39 0.006
gi|78000167 sorbin and SH3 domain containing 1 isoform 5 [Homo s... 39 0.006
gi|78000165 sorbin and SH3 domain containing 1 isoform 4 [Homo s... 39 0.006
gi|78000163 sorbin and SH3 domain containing 1 isoform 3 [Homo s... 39 0.006
gi|157412249 RUN and SH3 domain containing 1 isoform c [Homo sap... 39 0.007
gi|157412247 RUN and SH3 domain containing 1 isoform b [Homo sap... 39 0.007
gi|157412245 RUN and SH3 domain containing 1 isoform a [Homo sap... 39 0.007
gi|42476123 RUN and SH3 domain containing 1 isoform d [Homo sapi... 39 0.007
>gi|7705773 SH3-containing protein SH3GLB1 [Homo sapiens]
Length = 365
Score = 717 bits (1852), Expect = 0.0
Identities = 365/365 (100%), Positives = 365/365 (100%)
Query: 1 MNIMDFNVKKLAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLSKAECTKIWTEKIM 60
MNIMDFNVKKLAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLSKAECTKIWTEKIM
Sbjct: 1 MNIMDFNVKKLAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLSKAECTKIWTEKIM 60
Query: 61 KQTEVLLQPNPNARIEEFVYEKLDRKAPSRINNPELLGQYMIDAGTEFGPGTAYGNALIK 120
KQTEVLLQPNPNARIEEFVYEKLDRKAPSRINNPELLGQYMIDAGTEFGPGTAYGNALIK
Sbjct: 61 KQTEVLLQPNPNARIEEFVYEKLDRKAPSRINNPELLGQYMIDAGTEFGPGTAYGNALIK 120
Query: 121 CGETQKRIGTADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLK 180
CGETQKRIGTADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLK
Sbjct: 121 CGETQKRIGTADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLK 180
Query: 181 KAKAAETRNSSEQELRITQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVEAQMTYYAQ 240
KAKAAETRNSSEQELRITQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVEAQMTYYAQ
Sbjct: 181 KAKAAETRNSSEQELRITQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVEAQMTYYAQ 240
Query: 241 CYQYMLDLQKQLGSFPSNYLSNNNQTSVTPVPSVLPNAIGSSAMASTSGLVITSPSNLSD 300
CYQYMLDLQKQLGSFPSNYLSNNNQTSVTPVPSVLPNAIGSSAMASTSGLVITSPSNLSD
Sbjct: 241 CYQYMLDLQKQLGSFPSNYLSNNNQTSVTPVPSVLPNAIGSSAMASTSGLVITSPSNLSD 300
Query: 301 LKECSGSRKARVLYDYDAANSTELSLLADEVITVFSVVGMDSDWLMGERGNQKGKVPITY 360
LKECSGSRKARVLYDYDAANSTELSLLADEVITVFSVVGMDSDWLMGERGNQKGKVPITY
Sbjct: 301 LKECSGSRKARVLYDYDAANSTELSLLADEVITVFSVVGMDSDWLMGERGNQKGKVPITY 360
Query: 361 LELLN 365
LELLN
Sbjct: 361 LELLN 365
>gi|9910352 SH3-domain GRB2-like endophilin B2 [Homo sapiens]
Length = 395
Score = 466 bits (1198), Expect = e-131
Identities = 237/396 (59%), Positives = 295/396 (74%), Gaps = 35/396 (8%)
Query: 4 MDFNVKKLAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLSKAECTKIWTEKIMKQT 63
MDFN+KKLA+DAG F +RAVQFTEEK GQAEKTELDAH ENLL++A+ TK WTEKI++QT
Sbjct: 1 MDFNMKKLASDAGIFFTRAVQFTEEKFGQAEKTELDAHFENLLARADSTKNWTEKILRQT 60
Query: 64 EVLLQPNPNARIEEFVYEKLDRKAPSRINNPELLGQYMIDAGTEFGPGTAYGNALIKCGE 123
EVLLQPNP+AR+EEF+YEKLDRK PSR+ N ELL QYM DA +E GP T YG LIK E
Sbjct: 61 EVLLQPNPSARVEEFLYEKLDRKVPSRVTNGELLAQYMADAASELGPTTPYGKTLIKVAE 120
Query: 124 TQKRIGTADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLKKAK 183
+K++G A+R+ I T++++FLTPLRNF+EGD+KTI+KER+LLQN+RLDLDA K RLKKAK
Sbjct: 121 AEKQLGAAERDFIHTASISFLTPLRNFLEGDWKTISKERRLLQNRRLDLDACKARLKKAK 180
Query: 184 AAETR-----------------------------NSSEQELRITQSEFDRQAEITRLLLE 214
AAE + + +EQELR+ Q+EFDRQAE+TRLLLE
Sbjct: 181 AAEAKATTVPDFQETRPRNYILSASASALWNDEVDKAEQELRVAQTEFDRQAEVTRLLLE 240
Query: 215 GISSTHAHHLRCLNDFVEAQMTYYAQCYQYMLDLQKQLGSFPSNYLSNNNQTSVTPVPSV 274
GISSTH +HLRCL++FV++Q TYYAQCY++MLDLQKQLG FP ++ S P+ S
Sbjct: 241 GISSTHVNHLRCLHEFVKSQTTYYAQCYRHMLDLQKQLGRFPGTFVGTTEPAS-PPLSST 299
Query: 275 LPNAIGSSAMASTSGLVITSPSNLSDLKE-----CSGSRKARVLYDYDAANSTELSLLAD 329
P ++ S + P S E SG+RKARVLYDY+AA+S+EL+LLAD
Sbjct: 300 SPTTAAATMPVVPSVASLAPPGEASLCLEEVAPPASGTRKARVLYDYEAADSSELALLAD 359
Query: 330 EVITVFSVVGMDSDWLMGERGNQKGKVPITYLELLN 365
E+ITV+S+ GMD DWL+GERGN+KGKVP+TYLELL+
Sbjct: 360 ELITVYSLPGMDPDWLIGERGNKKGKVPVTYLELLS 395
>gi|4506929 SH3-domain GRB2-like 1 [Homo sapiens]
Length = 368
Score = 126 bits (317), Expect = 3e-29
Identities = 98/367 (26%), Positives = 162/367 (44%), Gaps = 38/367 (10%)
Query: 21 RAVQFTEEKLGQAEKTELDAHLENLLSKAECTKIWTEKIMKQTEVLLQPNPNARIEEFVY 80
+A Q EK+G AE T+LD + + K + T +++ +T LQPNP +R + +
Sbjct: 12 KASQLVSEKVGGAEGTKLDDDFKEMEKKVDVTSKAVTEVLARTIEYLQPNPASRAKLTML 71
Query: 81 EKLDR-----KAPSRINNPELLGQYMIDAGTEFGPGTAYGNALIKCGETQKRIGTADREL 135
+ + K P + LLG+ MI G E G + +G+AL+ GE+ KR+ L
Sbjct: 72 NTVSKIRGQVKNPGYPQSEGLLGECMIRHGKELGGESNFGDALLDAGESMKRLAEVKDSL 131
Query: 136 IQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLKKAKAAETRNSSEQEL 195
NF+ PL+N E D K I K L+ +RLD D K R K ++EL
Sbjct: 132 DIEVKQNFIDPLQNLCEKDLKEIQHHLKKLEGRRLDFDYKKKRQGKI--------PDEEL 183
Query: 196 RITQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVEAQMTYYAQCYQYMLDLQKQLGSF 255
R +F+ E+ + + T + L+ V+AQ+ Y+ Q Q + +L ++L
Sbjct: 184 RQALEKFEESKEVAETSMHNLLETDIEQVSQLSALVDAQLDYHRQAVQILDELAEKL-KR 242
Query: 256 PSNYLSNNNQTSVTPVP------------------SVLPNAIGSSAMASTSGLVITSPSN 297
S+ + P P + P SS+ S+ + T +
Sbjct: 243 RMREASSRPKREYKPKPREPFDLGEPEQSNGGFPCTTAPKIAASSSFRSSDKPIRTPSRS 302
Query: 298 LSDLKECSGSRKARVLYDYDAANSTELSLLADEVITVFSVVGMDSDWLMGERGNQKGKVP 357
+ L + S + LYD++ N EL +VIT+ + + D +W G Q G P
Sbjct: 303 MPPLDQPS----CKALYDFEPENDGELGFHEGDVITLTNQI--DENWYEGMLDGQSGFFP 356
Query: 358 ITYLELL 364
++Y+E+L
Sbjct: 357 LSYVEVL 363
>gi|223468657 SH3-domain GRB2-like 3 [Homo sapiens]
Length = 347
Score = 112 bits (280), Expect = 5e-25
Identities = 93/353 (26%), Positives = 151/353 (42%), Gaps = 31/353 (8%)
Query: 21 RAVQFTEEKLGQAEKTELDAHLENLLSKAECTKIWTEKIMKQTEVLLQPNPNARIEEFVY 80
+A Q EK+ AE T+LD ++ K + T +I+ +T LQPNP R + +
Sbjct: 12 KASQLFSEKISGAEGTKLDDEFLDMERKIDVTNKVVAEILSKTTEYLQPNPAYRAKLGML 71
Query: 81 EKLDR-----KAPSRINNPELLGQYMIDAGTEFGPGTAYGNALIKCGETQKRIGTADREL 135
+ + K LLG M+ G E G + +GNALI+ GE+ K + L
Sbjct: 72 NTVSKIRGQVKTTGYPQTEGLLGDCMLKYGKELGEDSTFGNALIEVGESMKLMAEVKDSL 131
Query: 136 IQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLKKAKAAETRNSSEQEL 195
F+ PL+ + D K I K L+ +RLD D K R+ K E R + E
Sbjct: 132 DINVKQTFIDPLQLLQDKDLKEIGHHLKKLEGRRLDYDYKKKRVGKIPDEEVRQAVE--- 188
Query: 196 RITQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVEAQMTYYAQCYQYMLDLQKQLGSF 255
+F+ E+ + + L F+EA + Y+ Q + + +LQ +L
Sbjct: 189 -----KFEESKELAERSMFNFLENDVEQVSQLAVFIEAALDYHRQSTEILQELQSKL--- 240
Query: 256 PSNYLSNNNQTSVTPVPSVLPNAIGSSAM----ASTSGLVITSPSNLSDLKECSGSRKAR 311
+ S P P + S+ ST+ +V T+ SN+ + C R
Sbjct: 241 ----QMRISAASSVPRREYKPRPVKRSSSELNGVSTTSVVKTTGSNIPMDQPC-----CR 291
Query: 312 VLYDYDAANSTELSLLADEVITVFSVVGMDSDWLMGERGNQKGKVPITYLELL 364
LYD++ N EL ++IT+ + + D +W G + G PI Y+E++
Sbjct: 292 GLYDFEPENQGELGFKEGDIITLTNQI--DENWYEGMIHGESGFFPINYVEVI 342
>gi|4506931 SH3-domain GRB2-like 2 [Homo sapiens]
Length = 352
Score = 112 bits (279), Expect = 7e-25
Identities = 92/352 (26%), Positives = 146/352 (41%), Gaps = 24/352 (6%)
Query: 21 RAVQFTEEKLGQAEKTELDAHLENLLSKAECTKIWTEKIMKQTEVLLQPNPNARIEEFVY 80
+A Q EK+G AE T+LD + + K + T +IM +T LQPNP +R + +
Sbjct: 12 KATQKVSEKVGGAEGTKLDDDFKEMERKVDVTSRAVMEIMTKTIEYLQPNPASRAKLSMI 71
Query: 81 EKLDR-----KAPSRINNPELLGQYMIDAGTEFGPGTAYGNALIKCGETQKRIGTADREL 135
+ + K P LL + M+ G E G +G AL + GE + + L
Sbjct: 72 NTMSKIRGQEKGPGYPQAEALLAEAMLKFGRELGDDCNFGPALGEVGEAMRELSEVKDSL 131
Query: 136 IQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLKKAKAAETRNSSEQEL 195
NF+ PL+N + D + I K L+ +RLD D K R K ++EL
Sbjct: 132 DIEVKQNFIDPLQNLHDKDLREIQHHLKKLEGRRLDFDYKKKRQGKI--------PDEEL 183
Query: 196 RITQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVEAQMTYYAQCYQYMLDLQKQLGSF 255
R +FD EI + + + L+ V+AQ+ Y+ Q Q + + +L
Sbjct: 184 RQALEKFDESKEIAESSMFNLLEMDIEQVSQLSALVQAQLEYHKQAVQILQQVTVRLEE- 242
Query: 256 PSNYLSNNNQTSVTPVPSV---LPNAIGSSAMASTSGLVITSPSNLSDLKECSGSRKARV 312
S+ + P P + P + S PS + + C R
Sbjct: 243 RIRQASSQPRREYQPKPRMSLEFPTGDSTQPNGGLSHTGTPKPSGVQMDQPC-----CRA 297
Query: 313 LYDYDAANSTELSLLADEVITVFSVVGMDSDWLMGERGNQKGKVPITYLELL 364
LYD++ N EL ++IT+ + + D +W G G PI Y+E+L
Sbjct: 298 LYDFEPENEGELGFKEGDIITLTNQI--DENWYEGMLHGHSGFFPINYVEIL 347
>gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens]
Length = 818
Score = 50.8 bits (120), Expect = 2e-06
Identities = 62/265 (23%), Positives = 112/265 (42%), Gaps = 40/265 (15%)
Query: 20 SRAVQFTEEKLGQAEKTE-LDAHLENLLSKAECTKIWTEKIMKQTEVLLQPNPNARIEEF 78
+R Q + +G+AEKTE L L + + E K + K+ LQ A +
Sbjct: 6 NRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACLQGQQGAEAD-- 63
Query: 79 VYEKLDRKAPSRINNPELLGQYMIDAGTEFGPGTAYGNALIKCGETQKRIGTADRELIQT 138
K +K P L Q +++ G T G L CGET+ ++ +ELI
Sbjct: 64 ---KRSKKLPLTT-----LAQCLMEGSAILGDDTLLGKMLKLCGETEDKLA---QELIHF 112
Query: 139 SAL---NFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLKKAKAAETRNSSEQ-- 193
+ + PL E + I K+RK L LD+D+++TR ++ + +SS Q
Sbjct: 113 ELQVERDVIEPLFLLAEVEIPNIQKQRKHLAKLVLDMDSSRTRWQQTSKSSGLSSSLQPA 172
Query: 194 --ELRITQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVEAQMTYYAQCYQYMLDLQKQ 251
+ + E + A + + +S+ + FV ++ YA +Q ++++Q +
Sbjct: 173 GAKADALREEMEEAANRVEICRDQLSAD-------MYSFVAKEID-YANYFQTLIEVQAE 224
Query: 252 LGSFPSNYLSNNNQTSVTPVPSVLP 276
++ S+T + +VLP
Sbjct: 225 Y-----------HRKSLTLLQAVLP 238
>gi|242117953 SH3 domain-containing protein C1orf113 isoform 1 [Homo
sapiens]
Length = 756
Score = 45.8 bits (107), Expect = 6e-05
Identities = 36/115 (31%), Positives = 50/115 (43%), Gaps = 9/115 (7%)
Query: 251 QLGSFPSNYL----SNNNQTSVTPVPSVLPNAIGSSAMASTSGLVITSPSNLSDLKECSG 306
QLG+FPSN++ S +PSV P G S L SP + L+ S
Sbjct: 128 QLGAFPSNFVELLDSGPPSLGNPDMPSVSP---GPQRPPKLSSLAYDSPPDY--LQTVSH 182
Query: 307 SRKARVLYDYDAANSTELSLLADEVITVFSVVGMDSDWLMGERGNQKGKVPITYL 361
RVL+DY EL+L +V+ V S D W GE ++G P ++
Sbjct: 183 PEVYRVLFDYQPEAPDELALRRGDVVKVLSKTTEDKGWWEGECQGRRGVFPDNFV 237
Score = 34.3 bits (77), Expect = 0.18
Identities = 16/58 (27%), Positives = 30/58 (51%), Gaps = 2/58 (3%)
Query: 308 RKARVLYDYDAANSTELSLLADEVITVFSVVGMDSDWLMGERGNQKGKVPITYLELLN 365
R +V + Y + EL L A E++ + + + W +G++ Q G P ++ELL+
Sbjct: 86 RWCKVNFSYSPEQADELKLQAGEIVEMIKEI--EDGWWLGKKNGQLGAFPSNFVELLD 141
>gi|242117948 SH3 domain-containing protein C1orf113 isoform 2 [Homo
sapiens]
Length = 645
Score = 45.8 bits (107), Expect = 6e-05
Identities = 36/115 (31%), Positives = 50/115 (43%), Gaps = 9/115 (7%)
Query: 251 QLGSFPSNYL----SNNNQTSVTPVPSVLPNAIGSSAMASTSGLVITSPSNLSDLKECSG 306
QLG+FPSN++ S +PSV P G S L SP + L+ S
Sbjct: 17 QLGAFPSNFVELLDSGPPSLGNPDMPSVSP---GPQRPPKLSSLAYDSPPDY--LQTVSH 71
Query: 307 SRKARVLYDYDAANSTELSLLADEVITVFSVVGMDSDWLMGERGNQKGKVPITYL 361
RVL+DY EL+L +V+ V S D W GE ++G P ++
Sbjct: 72 PEVYRVLFDYQPEAPDELALRRGDVVKVLSKTTEDKGWWEGECQGRRGVFPDNFV 126
>gi|193083145 SH3 domain containing 19 isoform c [Homo sapiens]
Length = 731
Score = 45.1 bits (105), Expect = 1e-04
Identities = 22/57 (38%), Positives = 32/57 (56%), Gaps = 2/57 (3%)
Query: 308 RKARVLYDYDAANSTELSLLADEVITVFSVVGMDSDWLMGERGNQKGKVPITYLELL 364
RKA+ LYD+ N ELS A ++IT + +D DW+ GE + G P Y++ L
Sbjct: 674 RKAKALYDFRGENEDELSFKAGDIIT--ELESVDDDWMSGELMGKSGIFPKNYIQFL 728
Score = 37.7 bits (86), Expect = 0.016
Identities = 20/60 (33%), Positives = 35/60 (58%), Gaps = 2/60 (3%)
Query: 305 SGSRKARVLYDYDAANSTELSLLADEVITVFSVVGMDSDWLMGERGNQKGKVPITYLELL 364
SG+ A VL+D+ A +L+L + E+ V+ + +D+DW G NQ G P Y++++
Sbjct: 436 SGAPHAVVLHDFPAEQVDDLNLTSGEI--VYLLEKIDTDWYRGNCRNQIGIFPANYVKVI 493
>gi|193083143 SH3 domain containing 19 isoform b [Homo sapiens]
Length = 767
Score = 45.1 bits (105), Expect = 1e-04
Identities = 22/57 (38%), Positives = 32/57 (56%), Gaps = 2/57 (3%)
Query: 308 RKARVLYDYDAANSTELSLLADEVITVFSVVGMDSDWLMGERGNQKGKVPITYLELL 364
RKA+ LYD+ N ELS A ++IT + +D DW+ GE + G P Y++ L
Sbjct: 710 RKAKALYDFRGENEDELSFKAGDIIT--ELESVDDDWMSGELMGKSGIFPKNYIQFL 764
Score = 37.7 bits (86), Expect = 0.016
Identities = 20/60 (33%), Positives = 35/60 (58%), Gaps = 2/60 (3%)
Query: 305 SGSRKARVLYDYDAANSTELSLLADEVITVFSVVGMDSDWLMGERGNQKGKVPITYLELL 364
SG+ A VL+D+ A +L+L + E+ V+ + +D+DW G NQ G P Y++++
Sbjct: 472 SGAPHAVVLHDFPAEQVDDLNLTSGEI--VYLLEKIDTDWYRGNCRNQIGIFPANYVKVI 529
>gi|193083141 SH3 domain containing 19 isoform a [Homo sapiens]
Length = 790
Score = 45.1 bits (105), Expect = 1e-04
Identities = 22/57 (38%), Positives = 32/57 (56%), Gaps = 2/57 (3%)
Query: 308 RKARVLYDYDAANSTELSLLADEVITVFSVVGMDSDWLMGERGNQKGKVPITYLELL 364
RKA+ LYD+ N ELS A ++IT + +D DW+ GE + G P Y++ L
Sbjct: 733 RKAKALYDFRGENEDELSFKAGDIIT--ELESVDDDWMSGELMGKSGIFPKNYIQFL 787
Score = 37.7 bits (86), Expect = 0.016
Identities = 20/60 (33%), Positives = 35/60 (58%), Gaps = 2/60 (3%)
Query: 305 SGSRKARVLYDYDAANSTELSLLADEVITVFSVVGMDSDWLMGERGNQKGKVPITYLELL 364
SG+ A VL+D+ A +L+L + E+ V+ + +D+DW G NQ G P Y++++
Sbjct: 495 SGAPHAVVLHDFPAEQVDDLNLTSGEI--VYLLEKIDTDWYRGNCRNQIGIFPANYVKVI 552
>gi|20149528 proline-serine-threonine phosphatase interacting
protein 1 [Homo sapiens]
Length = 416
Score = 43.5 bits (101), Expect = 3e-04
Identities = 67/256 (26%), Positives = 103/256 (40%), Gaps = 48/256 (18%)
Query: 153 GDYKTIAK-ERKLLQNKRLDLDAAKT-RLKKAKAAETRNSSEQELRITQSEFDRQAEITR 210
G K + K + K Q K +A + R A+ + R EQE R T F Q
Sbjct: 165 GHQKQVEKSQNKARQCKDSATEAERVYRQSIAQLEKVRAEWEQEHRTTCEAFQLQEFDRL 224
Query: 211 LLLEGISSTHAHHL--RCLND---FVEAQMTYYAQCYQYMLDL---QKQLGSFP------ 256
+L H++ L +C+ D + E ++T +D K G+ P
Sbjct: 225 TILRNALWVHSNQLSMQCVKDDELYEEVRLTLEGCSIDADIDSFIQAKSTGTEPPAPVPY 284
Query: 257 SNYLSNNNQTSVTPVPSVLPN------------------AIGSSAMASTSGLVITSPSNL 298
NY + T +T P + P+ ++ +SA AST L T N
Sbjct: 285 QNYY-DREVTPLTSSPGIQPSCGMIKRFSGLLHGSPKTTSLAASA-ASTETLTPTPERNE 342
Query: 299 S-----DLKECSGS-----RKARVLYDYDAANSTELSLLADEVITVFSVVGMDSDWLMGE 348
++E G+ ++ R LYDY A N EL L A +++ V ++ + W E
Sbjct: 343 GVYTAIAVQEIQGNPASPAQEYRALYDYTAQNPDELDLSAGDILEV--ILEGEDGWWTVE 400
Query: 349 RGNQKGKVPITYLELL 364
R Q+G VP +YLE L
Sbjct: 401 RNGQRGFVPGSYLEKL 416
>gi|47087157 nebulette non-muscle isoform [Homo sapiens]
Length = 270
Score = 43.1 bits (100), Expect = 4e-04
Identities = 28/97 (28%), Positives = 45/97 (46%), Gaps = 4/97 (4%)
Query: 271 VPSVLPNAIGSSAMASTSGLVITSPSNLSDLKECSGSRKARVLYDYDAANSTELSLLADE 330
V VLP A S + TS S++ ++ R R +YDY A + E+S +
Sbjct: 176 VAPVLPGAYQQSHSQGYGYMHQTSVSSMRSMQHSPNLRTYRAMYDYSAQDEDEVSFRDGD 235
Query: 331 VITVFSVVGMDSDWLMG--ERGNQKGKVPITYLELLN 365
I +V +D W+ G +R + G +P Y+E +N
Sbjct: 236 YIV--NVQPIDDGWMYGTVQRTGRTGMLPANYIEFVN 270
>gi|23397574 sorting nexin 33 [Homo sapiens]
Length = 574
Score = 42.7 bits (99), Expect = 5e-04
Identities = 20/57 (35%), Positives = 33/57 (57%), Gaps = 2/57 (3%)
Query: 309 KARVLYDYDAANSTELSLLADEVITVFSVVGMDSDWLMGERG-NQKGKVPITYLELL 364
K R LYD+ + N E+S+ DE + +FS +D WL G+ + G P +Y+E++
Sbjct: 4 KGRALYDFHSENKEEISIQQDEDLVIFSETSLDG-WLQGQNSRGETGLFPASYVEIV 59
>gi|5453758 nebulette sarcomeric isoform [Homo sapiens]
Length = 1014
Score = 42.4 bits (98), Expect = 7e-04
Identities = 27/94 (28%), Positives = 44/94 (46%), Gaps = 4/94 (4%)
Query: 274 VLPNAIGSSAMASTSGLVITSPSNLSDLKECSGSRKARVLYDYDAANSTELSLLADEVIT 333
VLP A S + TS S++ ++ R R +YDY A + E+S + I
Sbjct: 923 VLPGAYQQSHSQGYGYMHQTSVSSMRSMQHSPNLRTYRAMYDYSAQDEDEVSFRDGDYIV 982
Query: 334 VFSVVGMDSDWLMG--ERGNQKGKVPITYLELLN 365
+V +D W+ G +R + G +P Y+E +N
Sbjct: 983 --NVQPIDDGWMYGTVQRTGRTGMLPANYIEFVN 1014
>gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]
Length = 1220
Score = 40.8 bits (94), Expect = 0.002
Identities = 29/115 (25%), Positives = 47/115 (40%), Gaps = 25/115 (21%)
Query: 249 QKQLGSFPSNYLSNNNQTSVTPVPSVLPNAIGSSAMASTSGLVITSPSNLSDLKECSGSR 308
++Q+G FP+NY+ + + P+ P + +A+ G
Sbjct: 1122 KRQIGWFPANYVKLLSPGTSKITPTEPPKSTALAAVCQVIG------------------- 1162
Query: 309 KARVLYDYDAANSTELSLLADEVITVFSVVGMDSDWLMGERGNQKGKVPITYLEL 363
+YDY A N EL+ ++I V + D DW GE Q G P Y++L
Sbjct: 1163 ----MYDYTAQNDDELAFNKGQIINVLN--KEDPDWWKGEVNGQVGLFPSNYVKL 1211
Score = 34.7 bits (78), Expect = 0.14
Identities = 23/73 (31%), Positives = 36/73 (49%), Gaps = 3/73 (4%)
Query: 293 TSPSNLSDLKECSGSRKARVLYDYDAANSTELSLLADEVITVFSVVGMDSDWLMGERGNQ 352
+SPS + E +A+ LY + A L+ ++VITV M W GE Q
Sbjct: 901 SSPSPVLGQGEKVEGLQAQALYPWRAKKDNHLNFNKNDVITVLEQQDM---WWFGEVQGQ 957
Query: 353 KGKVPITYLELLN 365
KG P +Y++L++
Sbjct: 958 KGWFPKSYVKLIS 970
>gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]
Length = 1721
Score = 40.8 bits (94), Expect = 0.002
Identities = 29/115 (25%), Positives = 47/115 (40%), Gaps = 25/115 (21%)
Query: 249 QKQLGSFPSNYLSNNNQTSVTPVPSVLPNAIGSSAMASTSGLVITSPSNLSDLKECSGSR 308
++Q+G FP+NY+ + + P+ P + +A+ G
Sbjct: 1122 KRQIGWFPANYVKLLSPGTSKITPTEPPKSTALAAVCQVIG------------------- 1162
Query: 309 KARVLYDYDAANSTELSLLADEVITVFSVVGMDSDWLMGERGNQKGKVPITYLEL 363
+YDY A N EL+ ++I V + D DW GE Q G P Y++L
Sbjct: 1163 ----MYDYTAQNDDELAFNKGQIINVLN--KEDPDWWKGEVNGQVGLFPSNYVKL 1211
Score = 34.7 bits (78), Expect = 0.14
Identities = 23/73 (31%), Positives = 36/73 (49%), Gaps = 3/73 (4%)
Query: 293 TSPSNLSDLKECSGSRKARVLYDYDAANSTELSLLADEVITVFSVVGMDSDWLMGERGNQ 352
+SPS + E +A+ LY + A L+ ++VITV M W GE Q
Sbjct: 901 SSPSPVLGQGEKVEGLQAQALYPWRAKKDNHLNFNKNDVITVLEQQDM---WWFGEVQGQ 957
Query: 353 KGKVPITYLELLN 365
KG P +Y++L++
Sbjct: 958 KGWFPKSYVKLIS 970
>gi|50843948 Rho GTPase activating protein 10 [Homo sapiens]
Length = 786
Score = 40.8 bits (94), Expect = 0.002
Identities = 32/109 (29%), Positives = 55/109 (50%), Gaps = 12/109 (11%)
Query: 259 YLSNNNQTSVTPVPSVLPNAIGSSAMASTSGLVITSPSNLSDLK-ECSGSRKARVLYDYD 317
+L+ + T+ + +V P + GSS + P+ ++D E SRKAR +Y +
Sbjct: 687 WLNPQSPTTTSSNSAVTPLSPGSSPFP------FSPPATVADKPPESIRSRKARAVYPCE 740
Query: 318 AANSTELSLLADEVITVFSVV--GMDSDWLMGERGNQKGKVPITYLELL 364
A +S+ELS E+ +F V + WL G ++G +P Y++LL
Sbjct: 741 AEHSSELSF---EIGAIFEDVQTSREPGWLEGTLNGKRGLIPQNYVKLL 786
>gi|197304715 vav 2 guanine nucleotide exchange factor isoform 1
[Homo sapiens]
Length = 878
Score = 39.7 bits (91), Expect = 0.004
Identities = 18/49 (36%), Positives = 28/49 (57%)
Query: 314 YDYDAANSTELSLLADEVITVFSVVGMDSDWLMGERGNQKGKVPITYLE 362
Y++ A + ELSL +V+ ++S +G D W GE + G P TY+E
Sbjct: 825 YNFAARDMRELSLREGDVVRIYSRIGGDQGWWKGETNGRIGWFPSTYVE 873
>gi|40549448 vav 2 guanine nucleotide exchange factor isoform 2
[Homo sapiens]
Length = 839
Score = 39.7 bits (91), Expect = 0.004
Identities = 18/49 (36%), Positives = 28/49 (57%)
Query: 314 YDYDAANSTELSLLADEVITVFSVVGMDSDWLMGERGNQKGKVPITYLE 362
Y++ A + ELSL +V+ ++S +G D W GE + G P TY+E
Sbjct: 786 YNFAARDMRELSLREGDVVRIYSRIGGDQGWWKGETNGRIGWFPSTYVE 834
>gi|4507249 signal transducing adaptor molecule 1 [Homo sapiens]
Length = 540
Score = 39.3 bits (90), Expect = 0.006
Identities = 25/77 (32%), Positives = 38/77 (49%), Gaps = 3/77 (3%)
Query: 285 ASTSGLVITSPSNLSDLKECSGSRKARVLYDYDAANSTELSLLADEVITVFSVVGMDSDW 344
++T + S S+L + G RK R +YD++AA EL+ A E+ITV D +W
Sbjct: 191 STTLSTLYPSTSSLLTNHQHEG-RKVRAIYDFEAAEDNELTFKAGEIITVLD--DSDPNW 247
Query: 345 LMGERGNQKGKVPITYL 361
GE G P ++
Sbjct: 248 WKGETHQGIGLFPSNFV 264
>gi|78000171 sorbin and SH3 domain containing 1 isoform 7 [Homo
sapiens]
Length = 740
Score = 39.3 bits (90), Expect = 0.006
Identities = 25/71 (35%), Positives = 37/71 (52%), Gaps = 5/71 (7%)
Query: 297 NLSDL-KECSGS--RKARVLYDYDAANSTELSLLADEVITVFSVVGMDSDWLMGERGNQK 353
N+ D K SGS R AR +D+ A EL L +++ ++ + D +W GE +
Sbjct: 488 NIDDTAKRKSGSEMRPARAKFDFKAQTLKELPLQKGDIVYIYKQI--DQNWYEGEHHGRV 545
Query: 354 GKVPITYLELL 364
G P TY+ELL
Sbjct: 546 GIFPRTYIELL 556
>gi|78000169 sorbin and SH3 domain containing 1 isoform 6 [Homo
sapiens]
Length = 781
Score = 39.3 bits (90), Expect = 0.006
Identities = 25/71 (35%), Positives = 37/71 (52%), Gaps = 5/71 (7%)
Query: 297 NLSDL-KECSGS--RKARVLYDYDAANSTELSLLADEVITVFSVVGMDSDWLMGERGNQK 353
N+ D K SGS R AR +D+ A EL L +++ ++ + D +W GE +
Sbjct: 529 NIDDTAKRKSGSEMRPARAKFDFKAQTLKELPLQKGDIVYIYKQI--DQNWYEGEHHGRV 586
Query: 354 GKVPITYLELL 364
G P TY+ELL
Sbjct: 587 GIFPRTYIELL 597
>gi|78000167 sorbin and SH3 domain containing 1 isoform 5 [Homo
sapiens]
Length = 905
Score = 39.3 bits (90), Expect = 0.006
Identities = 25/71 (35%), Positives = 37/71 (52%), Gaps = 5/71 (7%)
Query: 297 NLSDL-KECSGS--RKARVLYDYDAANSTELSLLADEVITVFSVVGMDSDWLMGERGNQK 353
N+ D K SGS R AR +D+ A EL L +++ ++ + D +W GE +
Sbjct: 633 NIDDTAKRKSGSEMRPARAKFDFKAQTLKELPLQKGDIVYIYKQI--DQNWYEGEHHGRV 690
Query: 354 GKVPITYLELL 364
G P TY+ELL
Sbjct: 691 GIFPRTYIELL 701
>gi|78000165 sorbin and SH3 domain containing 1 isoform 4 [Homo
sapiens]
Length = 1151
Score = 39.3 bits (90), Expect = 0.006
Identities = 25/71 (35%), Positives = 37/71 (52%), Gaps = 5/71 (7%)
Query: 297 NLSDL-KECSGS--RKARVLYDYDAANSTELSLLADEVITVFSVVGMDSDWLMGERGNQK 353
N+ D K SGS R AR +D+ A EL L +++ ++ + D +W GE +
Sbjct: 804 NIDDTAKRKSGSEMRPARAKFDFKAQTLKELPLQKGDIVYIYKQI--DQNWYEGEHHGRV 861
Query: 354 GKVPITYLELL 364
G P TY+ELL
Sbjct: 862 GIFPRTYIELL 872
>gi|78000163 sorbin and SH3 domain containing 1 isoform 3 [Homo
sapiens]
Length = 1292
Score = 39.3 bits (90), Expect = 0.006
Identities = 25/71 (35%), Positives = 37/71 (52%), Gaps = 5/71 (7%)
Query: 297 NLSDL-KECSGS--RKARVLYDYDAANSTELSLLADEVITVFSVVGMDSDWLMGERGNQK 353
N+ D K SGS R AR +D+ A EL L +++ ++ + D +W GE +
Sbjct: 782 NIDDTAKRKSGSEMRPARAKFDFKAQTLKELPLQKGDIVYIYKQI--DQNWYEGEHHGRV 839
Query: 354 GKVPITYLELL 364
G P TY+ELL
Sbjct: 840 GIFPRTYIELL 850
>gi|157412249 RUN and SH3 domain containing 1 isoform c [Homo
sapiens]
Length = 492
Score = 38.9 bits (89), Expect = 0.007
Identities = 22/57 (38%), Positives = 29/57 (50%), Gaps = 2/57 (3%)
Query: 308 RKARVLYDYDAANSTELSLLADEVITVFSVVGMDSDWLMGERGNQKGKVPITYLELL 364
R R L D+ AA +LS EV+ V + V D DWL R +G VP+ Y L+
Sbjct: 437 RAVRALCDHTAARPDQLSFRRGEVLRVITTV--DEDWLRCGRDGMEGLVPVGYTSLV 491
>gi|157412247 RUN and SH3 domain containing 1 isoform b [Homo
sapiens]
Length = 796
Score = 38.9 bits (89), Expect = 0.007
Identities = 22/57 (38%), Positives = 29/57 (50%), Gaps = 2/57 (3%)
Query: 308 RKARVLYDYDAANSTELSLLADEVITVFSVVGMDSDWLMGERGNQKGKVPITYLELL 364
R R L D+ AA +LS EV+ V + V D DWL R +G VP+ Y L+
Sbjct: 741 RAVRALCDHTAARPDQLSFRRGEVLRVITTV--DEDWLRCGRDGMEGLVPVGYTSLV 795
>gi|157412245 RUN and SH3 domain containing 1 isoform a [Homo
sapiens]
Length = 902
Score = 38.9 bits (89), Expect = 0.007
Identities = 22/57 (38%), Positives = 29/57 (50%), Gaps = 2/57 (3%)
Query: 308 RKARVLYDYDAANSTELSLLADEVITVFSVVGMDSDWLMGERGNQKGKVPITYLELL 364
R R L D+ AA +LS EV+ V + V D DWL R +G VP+ Y L+
Sbjct: 847 RAVRALCDHTAARPDQLSFRRGEVLRVITTV--DEDWLRCGRDGMEGLVPVGYTSLV 901
>gi|42476123 RUN and SH3 domain containing 1 isoform d [Homo
sapiens]
Length = 433
Score = 38.9 bits (89), Expect = 0.007
Identities = 22/57 (38%), Positives = 29/57 (50%), Gaps = 2/57 (3%)
Query: 308 RKARVLYDYDAANSTELSLLADEVITVFSVVGMDSDWLMGERGNQKGKVPITYLELL 364
R R L D+ AA +LS EV+ V + V D DWL R +G VP+ Y L+
Sbjct: 378 RAVRALCDHTAARPDQLSFRRGEVLRVITTV--DEDWLRCGRDGMEGLVPVGYTSLV 432
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.130 0.360
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,316,862
Number of Sequences: 37866
Number of extensions: 509110
Number of successful extensions: 1671
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 54
Number of HSP's successfully gapped in prelim test: 96
Number of HSP's that attempted gapping in prelim test: 1515
Number of HSP's gapped (non-prelim): 211
length of query: 365
length of database: 18,247,518
effective HSP length: 104
effective length of query: 261
effective length of database: 14,309,454
effective search space: 3734767494
effective search space used: 3734767494
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.