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Search of human proteins with 14141152
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|14141152 heterogeneous nuclear ribonucleoprotein M isoform a
[Homo sapiens]
(730 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|14141152 heterogeneous nuclear ribonucleoprotein M isoform a ... 1469 0.0
gi|157412270 heterogeneous nuclear ribonucleoprotein M isoform b... 1369 0.0
gi|33620747 myelin expression factor 2 [Homo sapiens] 494 e-139
gi|185135971 poly(A)-binding protein, cytoplasmic 1-like [Homo s... 73 1e-12
gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo s... 73 1e-12
gi|18201888 poly(A) binding protein, cytoplasmic 5 [Homo sapiens] 71 4e-12
gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Ho... 71 4e-12
gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo... 71 4e-12
gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Ho... 71 4e-12
gi|5803036 heterogeneous nuclear ribonucleoprotein A0 [Homo sapi... 70 5e-12
gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens] 70 9e-12
gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens] 69 1e-11
gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens] 60 9e-09
gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens] 60 9e-09
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 59 2e-08
gi|253970502 Ewing sarcoma breakpoint region 1 isoform 3 [Homo s... 56 1e-07
gi|253970500 Ewing sarcoma breakpoint region 1 isoform 1 [Homo s... 56 1e-07
gi|9994185 RNA binding motif protein 7 [Homo sapiens] 56 1e-07
gi|4557493 cleavage stimulation factor subunit 2 [Homo sapiens] 55 2e-07
gi|226497734 RNA binding motif protein 19 [Homo sapiens] 55 3e-07
gi|226497654 RNA binding motif protein 19 [Homo sapiens] 55 3e-07
gi|226497574 RNA binding motif protein 19 [Homo sapiens] 55 3e-07
gi|14149675 cleavage stimulation factor, 3' pre-RNA, subunit 2, ... 55 3e-07
gi|238776833 THO complex 4 [Homo sapiens] 54 4e-07
gi|253970504 Ewing sarcoma breakpoint region 1 isoform 4 [Homo s... 53 9e-07
gi|4885225 Ewing sarcoma breakpoint region 1 isoform 2 [Homo sap... 53 9e-07
gi|169234630 RNA binding motif protein 11 [Homo sapiens] 53 9e-07
gi|56699409 RNA binding motif protein, X-linked [Homo sapiens] 52 2e-06
gi|242117971 RNA binding motif protein, X-linked-like 1 [Homo sa... 52 3e-06
gi|21361809 RNA binding motif protein, X-linked-like 1 [Homo sap... 52 3e-06
>gi|14141152 heterogeneous nuclear ribonucleoprotein M isoform a
[Homo sapiens]
Length = 730
Score = 1469 bits (3803), Expect = 0.0
Identities = 730/730 (100%), Positives = 730/730 (100%)
Query: 1 MAAGVEAAAEVAATEIKMEEESGAPGVPSGNGAPGPKGEGERPAQNEKRKEKNIKRGGNR 60
MAAGVEAAAEVAATEIKMEEESGAPGVPSGNGAPGPKGEGERPAQNEKRKEKNIKRGGNR
Sbjct: 1 MAAGVEAAAEVAATEIKMEEESGAPGVPSGNGAPGPKGEGERPAQNEKRKEKNIKRGGNR 60
Query: 61 FEPYANPTKRYRAFITNIPFDVKWQSLKDLVKEKVGEVTYVELLMDAEGKSRGCAVVEFK 120
FEPYANPTKRYRAFITNIPFDVKWQSLKDLVKEKVGEVTYVELLMDAEGKSRGCAVVEFK
Sbjct: 61 FEPYANPTKRYRAFITNIPFDVKWQSLKDLVKEKVGEVTYVELLMDAEGKSRGCAVVEFK 120
Query: 121 MEESMKKAAEVLNKHSLSGRPLKVKEDPDGEHARRAMQKVMATTGGMGMGPGGPGMITIP 180
MEESMKKAAEVLNKHSLSGRPLKVKEDPDGEHARRAMQKVMATTGGMGMGPGGPGMITIP
Sbjct: 121 MEESMKKAAEVLNKHSLSGRPLKVKEDPDGEHARRAMQKVMATTGGMGMGPGGPGMITIP 180
Query: 181 PSILNNPNIPNEIIHALQAGRLGSTVFVANLDYKVGWKKLKEVFSMAGVVVRADILEDKD 240
PSILNNPNIPNEIIHALQAGRLGSTVFVANLDYKVGWKKLKEVFSMAGVVVRADILEDKD
Sbjct: 181 PSILNNPNIPNEIIHALQAGRLGSTVFVANLDYKVGWKKLKEVFSMAGVVVRADILEDKD 240
Query: 241 GKSRGIGTVTFEQSIEAVQAISMFNGQLLFDRPMHVKMDERALPKGDFFPPERPQQLPHG 300
GKSRGIGTVTFEQSIEAVQAISMFNGQLLFDRPMHVKMDERALPKGDFFPPERPQQLPHG
Sbjct: 241 GKSRGIGTVTFEQSIEAVQAISMFNGQLLFDRPMHVKMDERALPKGDFFPPERPQQLPHG 300
Query: 301 LGGIGMGLGPGGQPIDANHLNKGIGMGNIGPAGMGMEGIGFGINKMGGMEGPFGGGMENM 360
LGGIGMGLGPGGQPIDANHLNKGIGMGNIGPAGMGMEGIGFGINKMGGMEGPFGGGMENM
Sbjct: 301 LGGIGMGLGPGGQPIDANHLNKGIGMGNIGPAGMGMEGIGFGINKMGGMEGPFGGGMENM 360
Query: 361 GRFGSGMNMGRINEILSNALKRGEIIAKQGGGGGGGSVPGIERMGPGIDRLGGAGMERMG 420
GRFGSGMNMGRINEILSNALKRGEIIAKQGGGGGGGSVPGIERMGPGIDRLGGAGMERMG
Sbjct: 361 GRFGSGMNMGRINEILSNALKRGEIIAKQGGGGGGGSVPGIERMGPGIDRLGGAGMERMG 420
Query: 421 AGLGHGMDRVGSEIERMGLVMDRMGSVERMGSGIERMGPLGLDHMASSIERMGQTMERIG 480
AGLGHGMDRVGSEIERMGLVMDRMGSVERMGSGIERMGPLGLDHMASSIERMGQTMERIG
Sbjct: 421 AGLGHGMDRVGSEIERMGLVMDRMGSVERMGSGIERMGPLGLDHMASSIERMGQTMERIG 480
Query: 481 SGVERMGAGMGFGLERMAAPIDRVGQTIERMGSGVERMGPAIERMGLSMERMVPAGMGAG 540
SGVERMGAGMGFGLERMAAPIDRVGQTIERMGSGVERMGPAIERMGLSMERMVPAGMGAG
Sbjct: 481 SGVERMGAGMGFGLERMAAPIDRVGQTIERMGSGVERMGPAIERMGLSMERMVPAGMGAG 540
Query: 541 LERMGPVMDRMATGLERMGANNLERMGLERMGANSLERMGLERMGANSLERMGPAMGPAL 600
LERMGPVMDRMATGLERMGANNLERMGLERMGANSLERMGLERMGANSLERMGPAMGPAL
Sbjct: 541 LERMGPVMDRMATGLERMGANNLERMGLERMGANSLERMGLERMGANSLERMGPAMGPAL 600
Query: 601 GAGIERMGLAMGGGGGASFDRAIEMERGNFGGSFAGSFGGAGGHAPGVARKACQIFVRNL 660
GAGIERMGLAMGGGGGASFDRAIEMERGNFGGSFAGSFGGAGGHAPGVARKACQIFVRNL
Sbjct: 601 GAGIERMGLAMGGGGGASFDRAIEMERGNFGGSFAGSFGGAGGHAPGVARKACQIFVRNL 660
Query: 661 PFDFTWKMLKDKFNECGHVLYADIKMENGKSKGCGVVKFESPEVAERACRMMNGMKLSGR 720
PFDFTWKMLKDKFNECGHVLYADIKMENGKSKGCGVVKFESPEVAERACRMMNGMKLSGR
Sbjct: 661 PFDFTWKMLKDKFNECGHVLYADIKMENGKSKGCGVVKFESPEVAERACRMMNGMKLSGR 720
Query: 721 EIDVRIDRNA 730
EIDVRIDRNA
Sbjct: 721 EIDVRIDRNA 730
>gi|157412270 heterogeneous nuclear ribonucleoprotein M isoform b
[Homo sapiens]
Length = 691
Score = 1369 bits (3544), Expect = 0.0
Identities = 691/730 (94%), Positives = 691/730 (94%), Gaps = 39/730 (5%)
Query: 1 MAAGVEAAAEVAATEIKMEEESGAPGVPSGNGAPGPKGEGERPAQNEKRKEKNIKRGGNR 60
MAAGVEAAAEVAATEIKMEEESGAPGVPSGNGAPGPKGEGERPAQNEKRKEKNIKRGGNR
Sbjct: 1 MAAGVEAAAEVAATEIKMEEESGAPGVPSGNGAPGPKGEGERPAQNEKRKEKNIKRGGNR 60
Query: 61 FEPYANPTKRYRAFITNIPFDVKWQSLKDLVKEKVGEVTYVELLMDAEGKSRGCAVVEFK 120
FEPYANPTKRYRAFITNIPFDVKWQSLKDLVKEKVGEVTYVELLMDAEGKSRGCAVVEFK
Sbjct: 61 FEPYANPTKRYRAFITNIPFDVKWQSLKDLVKEKVGEVTYVELLMDAEGKSRGCAVVEFK 120
Query: 121 MEESMKKAAEVLNKHSLSGRPLKVKEDPDGEHARRAMQKVMATTGGMGMGPGGPGMITIP 180
MEESMKKAAEVLNKHSLSGRPLKVKEDPDGEHARRAMQK
Sbjct: 121 MEESMKKAAEVLNKHSLSGRPLKVKEDPDGEHARRAMQK--------------------- 159
Query: 181 PSILNNPNIPNEIIHALQAGRLGSTVFVANLDYKVGWKKLKEVFSMAGVVVRADILEDKD 240
AGRLGSTVFVANLDYKVGWKKLKEVFSMAGVVVRADILEDKD
Sbjct: 160 ------------------AGRLGSTVFVANLDYKVGWKKLKEVFSMAGVVVRADILEDKD 201
Query: 241 GKSRGIGTVTFEQSIEAVQAISMFNGQLLFDRPMHVKMDERALPKGDFFPPERPQQLPHG 300
GKSRGIGTVTFEQSIEAVQAISMFNGQLLFDRPMHVKMDERALPKGDFFPPERPQQLPHG
Sbjct: 202 GKSRGIGTVTFEQSIEAVQAISMFNGQLLFDRPMHVKMDERALPKGDFFPPERPQQLPHG 261
Query: 301 LGGIGMGLGPGGQPIDANHLNKGIGMGNIGPAGMGMEGIGFGINKMGGMEGPFGGGMENM 360
LGGIGMGLGPGGQPIDANHLNKGIGMGNIGPAGMGMEGIGFGINKMGGMEGPFGGGMENM
Sbjct: 262 LGGIGMGLGPGGQPIDANHLNKGIGMGNIGPAGMGMEGIGFGINKMGGMEGPFGGGMENM 321
Query: 361 GRFGSGMNMGRINEILSNALKRGEIIAKQGGGGGGGSVPGIERMGPGIDRLGGAGMERMG 420
GRFGSGMNMGRINEILSNALKRGEIIAKQGGGGGGGSVPGIERMGPGIDRLGGAGMERMG
Sbjct: 322 GRFGSGMNMGRINEILSNALKRGEIIAKQGGGGGGGSVPGIERMGPGIDRLGGAGMERMG 381
Query: 421 AGLGHGMDRVGSEIERMGLVMDRMGSVERMGSGIERMGPLGLDHMASSIERMGQTMERIG 480
AGLGHGMDRVGSEIERMGLVMDRMGSVERMGSGIERMGPLGLDHMASSIERMGQTMERIG
Sbjct: 382 AGLGHGMDRVGSEIERMGLVMDRMGSVERMGSGIERMGPLGLDHMASSIERMGQTMERIG 441
Query: 481 SGVERMGAGMGFGLERMAAPIDRVGQTIERMGSGVERMGPAIERMGLSMERMVPAGMGAG 540
SGVERMGAGMGFGLERMAAPIDRVGQTIERMGSGVERMGPAIERMGLSMERMVPAGMGAG
Sbjct: 442 SGVERMGAGMGFGLERMAAPIDRVGQTIERMGSGVERMGPAIERMGLSMERMVPAGMGAG 501
Query: 541 LERMGPVMDRMATGLERMGANNLERMGLERMGANSLERMGLERMGANSLERMGPAMGPAL 600
LERMGPVMDRMATGLERMGANNLERMGLERMGANSLERMGLERMGANSLERMGPAMGPAL
Sbjct: 502 LERMGPVMDRMATGLERMGANNLERMGLERMGANSLERMGLERMGANSLERMGPAMGPAL 561
Query: 601 GAGIERMGLAMGGGGGASFDRAIEMERGNFGGSFAGSFGGAGGHAPGVARKACQIFVRNL 660
GAGIERMGLAMGGGGGASFDRAIEMERGNFGGSFAGSFGGAGGHAPGVARKACQIFVRNL
Sbjct: 562 GAGIERMGLAMGGGGGASFDRAIEMERGNFGGSFAGSFGGAGGHAPGVARKACQIFVRNL 621
Query: 661 PFDFTWKMLKDKFNECGHVLYADIKMENGKSKGCGVVKFESPEVAERACRMMNGMKLSGR 720
PFDFTWKMLKDKFNECGHVLYADIKMENGKSKGCGVVKFESPEVAERACRMMNGMKLSGR
Sbjct: 622 PFDFTWKMLKDKFNECGHVLYADIKMENGKSKGCGVVKFESPEVAERACRMMNGMKLSGR 681
Query: 721 EIDVRIDRNA 730
EIDVRIDRNA
Sbjct: 682 EIDVRIDRNA 691
>gi|33620747 myelin expression factor 2 [Homo sapiens]
Length = 600
Score = 494 bits (1272), Expect = e-139
Identities = 315/710 (44%), Positives = 394/710 (55%), Gaps = 174/710 (24%)
Query: 35 GPKGEGERPAQNEKR--KEKNI-KRGGNRFEPYANPTK----------RYRAFITNIPFD 81
G K E + A+ EK KEK+ + NRF PY+ R R FI+NIP+D
Sbjct: 51 GVKMENDESAKEEKSDLKEKSTGSKKANRFHPYSKDKNSGTGEKKGPNRNRVFISNIPYD 110
Query: 82 VKWQSLKDLVKEKVGEVTYVELLMDAEGKSRGCAVVEFKMEESMKKAAEVLNKHSLSGRP 141
+KWQ++KDL++EKVGEVTYVEL DAEGKSRGC VVEFK EE +KKA E +NK+ LSGRP
Sbjct: 111 MKWQAIKDLMREKVGEVTYVELFKDAEGKSRGCGVVEFKDEEFVKKALETMNKYDLSGRP 170
Query: 142 LKVKEDPDGEHARRAMQKVMATTGGMGMGPGGPGMITIPPSILNNPNIPNEIIHALQAGR 201
L +KEDPDGE+ARRA+Q+ + G + G G++ +PPSILNNPNIP E+I LQAGR
Sbjct: 171 LNIKEDPDGENARRALQRTGGSFPGGHVPDMGSGLMNLPPSILNNPNIPPEVISNLQAGR 230
Query: 202 LGSTVFVANLDYKVGWKKLKEVFSMAGVVVRADILEDKDGKSRGIGTVTFEQSIEAVQAI 261
LGST+FVANLD+KVGWKKLKEVFS+AG V RADI EDKDGKSRG+GTVTFEQ+IEAVQAI
Sbjct: 231 LGSTIFVANLDFKVGWKKLKEVFSIAGTVKRADIKEDKDGKSRGMGTVTFEQAIEAVQAI 290
Query: 262 SMFNGQLLFDRPMHVKMDERALPKGDFFPPE-RPQQLPHGLGGIGMGLGPGGQPIDANHL 320
SMFNGQ LFDRPMHVKMD++++P ++ + + QLP GLGGI
Sbjct: 291 SMFNGQFLFDRPMHVKMDDKSVPHEEYRSHDGKTPQLPRGLGGI---------------- 334
Query: 321 NKGIGMGNIGPAGMGMEGIGFGINKMGGMEGPFGGGMENMGRFGSGMNMGRINEILSNAL 380
GMG +GP G + I GG M N+G
Sbjct: 335 ----GMG-LGPGGQPISASQLNI----------GGVMGNLG------------------- 360
Query: 381 KRGEIIAKQGGGGGGGSVPGIERMGPGIDRLGGAGMERMGAGLGHGMDRVGSEIERMGLV 440
PG G G+D G GM R+G G+G G G E
Sbjct: 361 ------------------PG----GMGMDGPGFGGMNRIGGGIGFG----GLE------A 388
Query: 441 MDRMGSVERMGSGIERMGPLGLDHMASSIERMGQTMERIGSGVERMGAGMGFGLERMAAP 500
M+ MG G+ RMG L M SS+ER G +G GFG
Sbjct: 389 MNSMGGF----GGVGRMGELYRGAMTSSMER--------DFGRGDIGINRGFG------- 429
Query: 501 IDRVGQTIERMGSGVERMGPAIERMGLSMERMVPAGMGAGLERMGPVMDRMATGLERMGA 560
+ R+GS + +G R+G S V +G+ G+ M V M GL+RM
Sbjct: 430 -----DSFGRLGSAM--IGGFAGRIGSSNMGPVGSGISGGMGSMNSVTGGMGMGLDRM-- 480
Query: 561 NNLERMGLERMGANSLERMGLERMGANSLERMGPAMGPALGAGIERMGLAMGGGGGASFD 620
++S +RMGP G GA +
Sbjct: 481 -------------------------SSSFDRMGP-------------------GIGAILE 496
Query: 621 RAIEMERGNFGGSFAGSFGGAGGHAPGVARKACQIFVRNLPFDFTWKMLKDKFNECGHVL 680
R+I+M+RG G G + K QIFVRNLPFD TW+ LK+KF++CGHV+
Sbjct: 497 RSIDMDRGFLSGPMGS------GMRERIGSKGNQIFVRNLPFDLTWQKLKEKFSQCGHVM 550
Query: 681 YADIKMENGKSKGCGVVKFESPEVAERACRMMNGMKLSGREIDVRIDRNA 730
+A+IKMENGKSKGCG V+F+SPE AE+ACR+MNG+K+SGREIDVR+DRNA
Sbjct: 551 FAEIKMENGKSKGCGTVRFDSPESAEKACRIMNGIKISGREIDVRLDRNA 600
>gi|185135971 poly(A)-binding protein, cytoplasmic 1-like [Homo
sapiens]
Length = 614
Score = 72.8 bits (177), Expect = 1e-12
Identities = 62/239 (25%), Positives = 107/239 (44%), Gaps = 46/239 (19%)
Query: 47 EKRKEKNIKRGGNRFEPYANPTKRYRAFITNIPFDVKWQSLKDLVKEKVGEVTYVELLMD 106
+ R+E+ + G E + N ++ N+P DV Q L+DL + G++ V+++ D
Sbjct: 174 KSRREREAELGARALE-FTN------IYVKNLPVDVDEQGLQDLFSQ-FGKMLSVKVMRD 225
Query: 107 AEGKSRGCAVVEFKMEESMKKAAEVLNKHSLSGRPLKVKEDPDGEHARRAMQKVMATTGG 166
G SR V F+ E +KA +N +SGR L +A RA ++V
Sbjct: 226 NSGHSRCFGFVNFEKHEEAQKAVVHMNGKEVSGRLL---------YAGRAQKRV------ 270
Query: 167 MGMGPGGPGMITIPPSILNNPNIPNEIIHALQAGRL----GSTVFVANLDYKVGWKKLKE 222
N ++ RL G ++V NLD + KL++
Sbjct: 271 ------------------ERQNELKRRFEQMKQDRLRRYQGVNLYVKNLDDSIDDDKLRK 312
Query: 223 VFSMAGVVVRADILEDKDGKSRGIGTVTFEQSIEAVQAISMFNGQLLFDRPMHVKMDER 281
FS GV+ A ++ + G S+G G V F EA +A++ NG+++ +P++V + +R
Sbjct: 313 EFSPYGVITSAKVMTE-GGHSKGFGFVCFSSPEEATKAVTEMNGRIVGTKPLYVALAQR 370
Score = 50.4 bits (119), Expect = 6e-06
Identities = 28/80 (35%), Positives = 44/80 (55%), Gaps = 1/80 (1%)
Query: 646 PGVARKAC-QIFVRNLPFDFTWKMLKDKFNECGHVLYADIKMENGKSKGCGVVKFESPEV 704
PG+ + IF++NL K L D F+ G++L + + S+G G V FE+ E
Sbjct: 91 PGLRKSGVGNIFIKNLEDSIDNKALYDTFSTFGNILSCKVACDEHGSRGFGFVHFETHEA 150
Query: 705 AERACRMMNGMKLSGREIDV 724
A++A MNGM L+ R++ V
Sbjct: 151 AQQAINTMNGMLLNDRKVFV 170
Score = 48.5 bits (114), Expect = 2e-05
Identities = 27/67 (40%), Positives = 41/67 (61%), Gaps = 1/67 (1%)
Query: 655 IFVRNLPFDFTWKMLKDKFNECGHVLYADIKMEN-GKSKGCGVVKFESPEVAERACRMMN 713
I+V+NLP D + L+D F++ G +L + +N G S+ G V FE E A++A MN
Sbjct: 193 IYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRDNSGHSRCFGFVNFEKHEEAQKAVVHMN 252
Query: 714 GMKLSGR 720
G ++SGR
Sbjct: 253 GKEVSGR 259
Score = 47.0 bits (110), Expect = 6e-05
Identities = 44/182 (24%), Positives = 71/182 (39%), Gaps = 47/182 (25%)
Query: 96 GEVTYVELLMD-AEGKSRGCAVVEFKMEESMKKAAEVLNKHSLSGRPLKVKEDPDGEHAR 154
G + + + D A +S G A + F+ ++A + +N L G+P+++
Sbjct: 35 GPILSIRVCRDVATRRSLGYAYINFQQPADAERALDTMNFEMLKGQPIRI---------- 84
Query: 155 RAMQKVMATTGGMGMGPGGPGMITIPPSILNNPNIPNEIIHALQAGRLGSTVFVANLDYK 214
M + G+ G G +F+ NL+
Sbjct: 85 ------MWSQRDPGLRKSGVG-----------------------------NIFIKNLEDS 109
Query: 215 VGWKKLKEVFSMAGVVVRADILEDKDGKSRGIGTVTFEQSIEAVQAISMFNGQLLFDRPM 274
+ K L + FS G ++ + D+ G SRG G V FE A QAI+ NG LL DR +
Sbjct: 110 IDNKALYDTFSTFGNILSCKVACDEHG-SRGFGFVHFETHEAAQQAINTMNGMLLNDRKV 168
Query: 275 HV 276
V
Sbjct: 169 FV 170
Score = 42.4 bits (98), Expect = 0.002
Identities = 23/60 (38%), Positives = 32/60 (53%)
Query: 655 IFVRNLPFDFTWKMLKDKFNECGHVLYADIKMENGKSKGCGVVKFESPEVAERACRMMNG 714
++V+NL L+ +F+ G + A + E G SKG G V F SPE A +A MNG
Sbjct: 296 LYVKNLDDSIDDDKLRKEFSPYGVITSAKVMTEGGHSKGFGFVCFSSPEEATKAVTEMNG 355
>gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo
sapiens]
Length = 370
Score = 72.8 bits (177), Expect = 1e-12
Identities = 59/237 (24%), Positives = 107/237 (45%), Gaps = 40/237 (16%)
Query: 45 QNEKRKEKNIKRGGNRFEPYANPTKRYRAFITNIPFDVKWQSLKDLVKEKVGEVTYVELL 104
+N K +E ++ + F +I N D+ + LKD V K G+ V+++
Sbjct: 173 KNRKDREAELRSKASEFT---------NVYIKNFGGDMDDERLKD-VFSKYGKTLSVKVM 222
Query: 105 MDAEGKSRGCAVVEFKMEESMKKAAEVLNKHSLSGRPLKVKEDPDGEHARRAMQKVMATT 164
D+ GKS+G V F E+ KKA E +N ++G+ + V RA +KV
Sbjct: 223 TDSSGKSKGFGFVSFDSHEAAKKAVEEMNGRDINGQLIFVG---------RAQKKVERQA 273
Query: 165 GGMGMGPGGPGMITIPPSILNNPNIPNEIIHALQAGRLGSTVFVANLDYKVGWKKLKEVF 224
M + E I Q G +++ NLD + +KL+ F
Sbjct: 274 ELKQMFE----------------QLKRERIRGCQ----GVKLYIKNLDDTIDDEKLRNEF 313
Query: 225 SMAGVVVRADILEDKDGKSRGIGTVTFEQSIEAVQAISMFNGQLLFDRPMHVKMDER 281
S G + R ++++ +G+S+G G + F +A +A++ NG++L +P+ + + +R
Sbjct: 314 SSFGSISRVKVMQE-EGQSKGFGLICFSSPEDATKAMTEMNGRILGSKPLSIALAQR 369
Score = 51.2 bits (121), Expect = 3e-06
Identities = 37/112 (33%), Positives = 55/112 (49%), Gaps = 7/112 (6%)
Query: 620 DRAIEMERGNFGGS---FAGSFGGAGGHAPGVARKACQ---IFVRNLPFDFTWKMLKDKF 673
DRAIE G F G F + KA + ++++N D + LKD F
Sbjct: 151 DRAIEEMNGKLLKGCKVFVGRFKNRKDREAELRSKASEFTNVYIKNFGGDMDDERLKDVF 210
Query: 674 NECGHVLYADIKMEN-GKSKGCGVVKFESPEVAERACRMMNGMKLSGREIDV 724
++ G L + ++ GKSKG G V F+S E A++A MNG ++G+ I V
Sbjct: 211 SKYGKTLSVKVMTDSSGKSKGFGFVSFDSHEAAKKAVEEMNGRDINGQLIFV 262
Score = 47.0 bits (110), Expect = 6e-05
Identities = 23/79 (29%), Positives = 43/79 (54%), Gaps = 3/79 (3%)
Query: 651 KACQ---IFVRNLPFDFTWKMLKDKFNECGHVLYADIKMENGKSKGCGVVKFESPEVAER 707
+ CQ ++++NL + L+++F+ G + + E G+SKG G++ F SPE A +
Sbjct: 288 RGCQGVKLYIKNLDDTIDDEKLRNEFSSFGSISRVKVMQEEGQSKGFGLICFSSPEDATK 347
Query: 708 ACRMMNGMKLSGREIDVRI 726
A MNG L + + + +
Sbjct: 348 AMTEMNGRILGSKPLSIAL 366
Score = 44.7 bits (104), Expect = 3e-04
Identities = 25/84 (29%), Positives = 44/84 (52%), Gaps = 5/84 (5%)
Query: 204 STVFVANLDYKVGWKKLKEVFSMAGVVVRADILEDKDGKSRGIGTVTFEQSIEAVQAISM 263
+ V++ N + ++LK+VFS G + ++ D GKS+G G V+F+ A +A+
Sbjct: 190 TNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDSSGKSKGFGFVSFDSHEAAKKAVEE 249
Query: 264 -----FNGQLLFDRPMHVKMDERA 282
NGQL+F K++ +A
Sbjct: 250 MNGRDINGQLIFVGRAQKKVERQA 273
Score = 42.4 bits (98), Expect = 0.002
Identities = 26/81 (32%), Positives = 41/81 (50%), Gaps = 5/81 (6%)
Query: 655 IFVRNLPFDFTWKMLKDKFNECGHVLYADIKMENGKSKGCGVVKFESPEVAERACRMMNG 714
+F++NL K L + F+ G +L + + ++ SKG V F++ A+RA MNG
Sbjct: 100 VFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSDDQGSKGYAFVHFQNQSAADRAIEEMNG 159
Query: 715 MKLSGREIDV-----RIDRNA 730
L G ++ V R DR A
Sbjct: 160 KLLKGCKVFVGRFKNRKDREA 180
Score = 41.2 bits (95), Expect = 0.003
Identities = 24/64 (37%), Positives = 35/64 (54%), Gaps = 1/64 (1%)
Query: 206 VFVANLDYKVGWKKLKEVFSMAGVVVRADILEDKDGKSRGIGTVTFEQSIEAVQAISMFN 265
VF+ NLD + K L E FS G ++ + ++ D G S+G V F+ A +AI N
Sbjct: 100 VFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSDDQG-SKGYAFVHFQNQSAADRAIEEMN 158
Query: 266 GQLL 269
G+LL
Sbjct: 159 GKLL 162
>gi|18201888 poly(A) binding protein, cytoplasmic 5 [Homo sapiens]
Length = 382
Score = 70.9 bits (172), Expect = 4e-12
Identities = 57/214 (26%), Positives = 96/214 (44%), Gaps = 45/214 (21%)
Query: 74 FITNIPFDVKWQSLKDLVKEKVGEVTYVELLMDAEGKSRGCAVVEFKMEESMKKAAEVLN 133
F+ NI D+ + LK+L E G V+++ DA GKS+G V ++ E+ +KA L+
Sbjct: 202 FVKNIGDDIDDEKLKELFCE-YGPTESVKVIRDASGKSKGFGFVRYETHEAAQKAVLDLH 260
Query: 134 KHSLSGRPLKVKEDPDGEHARRAMQKVMATTGGMGMGPGGPGMITIPPSILNNPNIPNEI 193
S+ G+ L V RA +K+ E+
Sbjct: 261 GKSIDGKVLYVG---------RAQKKIERLA---------------------------EL 284
Query: 194 IHALQAGRL-------GSTVFVANLDYKVGWKKLKEVFSMAGVVVRADILEDKDGKSRGI 246
+ RL G +++ NLD + +KLKE FS G + RA ++ + G+ +G
Sbjct: 285 RRRFERLRLKEKSRPPGVPIYIKNLDETINDEKLKEEFSSFGSISRAKVMMEV-GQGKGF 343
Query: 247 GTVTFEQSIEAVQAISMFNGQLLFDRPMHVKMDE 280
G V F EA +A+ NG+++ +P+HV + +
Sbjct: 344 GVVCFSSFEEATKAVDEMNGRIVGSKPLHVTLGQ 377
Score = 45.8 bits (107), Expect = 1e-04
Identities = 25/72 (34%), Positives = 40/72 (55%)
Query: 655 IFVRNLPFDFTWKMLKDKFNECGHVLYADIKMENGKSKGCGVVKFESPEVAERACRMMNG 714
I+++NL + LK++F+ G + A + ME G+ KG GVV F S E A +A MNG
Sbjct: 304 IYIKNLDETINDEKLKEEFSSFGSISRAKVMMEVGQGKGFGVVCFSSFEEATKAVDEMNG 363
Query: 715 MKLSGREIDVRI 726
+ + + V +
Sbjct: 364 RIVGSKPLHVTL 375
Score = 42.0 bits (97), Expect = 0.002
Identities = 22/82 (26%), Positives = 43/82 (52%)
Query: 204 STVFVANLDYKVGWKKLKEVFSMAGVVVRADILEDKDGKSRGIGTVTFEQSIEAVQAISM 263
+ VFV N+ + +KLKE+F G ++ D GKS+G G V +E A +A+
Sbjct: 199 TNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKGFGFVRYETHEAAQKAVLD 258
Query: 264 FNGQLLFDRPMHVKMDERALPK 285
+G+ + + ++V ++ + +
Sbjct: 259 LHGKSIDGKVLYVGRAQKKIER 280
Score = 41.2 bits (95), Expect = 0.003
Identities = 23/70 (32%), Positives = 38/70 (54%)
Query: 655 IFVRNLPFDFTWKMLKDKFNECGHVLYADIKMENGKSKGCGVVKFESPEVAERACRMMNG 714
IF++NL + L F+ G++L + ++ SKG V F+S A RA MNG
Sbjct: 108 IFIKNLDKSIDNRALFYLFSAFGNILSCKVVCDDNGSKGYAYVHFDSLAAANRAIWHMNG 167
Query: 715 MKLSGREIDV 724
++L+ R++ V
Sbjct: 168 VRLNNRQVYV 177
Score = 41.2 bits (95), Expect = 0.003
Identities = 24/71 (33%), Positives = 41/71 (57%), Gaps = 1/71 (1%)
Query: 655 IFVRNLPFDFTWKMLKDKFNECGHVLYAD-IKMENGKSKGCGVVKFESPEVAERACRMMN 713
+FV+N+ D + LK+ F E G I+ +GKSKG G V++E+ E A++A ++
Sbjct: 201 VFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKGFGFVRYETHEAAQKAVLDLH 260
Query: 714 GMKLSGREIDV 724
G + G+ + V
Sbjct: 261 GKSIDGKVLYV 271
Score = 34.7 bits (78), Expect = 0.32
Identities = 27/93 (29%), Positives = 46/93 (49%), Gaps = 11/93 (11%)
Query: 206 VFVANLDYKVGWKKLKEVFSMAGVVVRADILEDKDGKSRGIGTVTFEQSIEAVQAISMFN 265
+F+ NLD + + L +FS G ++ ++ D +G S+G V F+ A +AI N
Sbjct: 108 IFIKNLDKSIDNRALFYLFSAFGNILSCKVVCDDNG-SKGYAYVHFDSLAAANRAIWHMN 166
Query: 266 GQLLFDRPMHVKMDERALPKGDF-FPPERPQQL 297
G V+++ R + G F FP ER ++
Sbjct: 167 G---------VRLNNRQVYVGRFKFPEERAAEV 190
>gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Homo
sapiens]
Length = 631
Score = 70.9 bits (172), Expect = 4e-12
Identities = 61/240 (25%), Positives = 108/240 (45%), Gaps = 48/240 (20%)
Query: 47 EKRKEKNIKRGGNRFEPYANPTKRYRAFITNIPFDVKWQSLKDLVKEKVGEVTYVELLMD 106
+ RKE+ + G E + N +I N +V +SLK+L + G+ V+++ D
Sbjct: 174 KSRKEREAELGAKAKE-FTN------VYIKNFGEEVDDESLKELFSQ-FGKTLSVKVMRD 225
Query: 107 AEGKSRGCAVVEFKMEESMKKAAEVLNKHSLSGRPLKV-----KEDPDGEHARRAMQKVM 161
GKS+G V ++ E KA E +N +SG+ + V K + E R+ Q
Sbjct: 226 PNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQ--- 282
Query: 162 ATTGGMGMGPGGPGMITIPPSILNNPNIPNEIIHALQAGRLGSTVFVANLDYKVGWKKLK 221
+ E I Q G +++ NLD + +KL+
Sbjct: 283 ---------------------------LKQERISRYQ----GVNLYIKNLDDTIDDEKLR 311
Query: 222 EVFSMAGVVVRADILEDKDGKSRGIGTVTFEQSIEAVQAISMFNGQLLFDRPMHVKMDER 281
+ FS G + A ++ + DG+S+G G V F EA +A++ NG+++ +P++V + +R
Sbjct: 312 KEFSPFGSITSAKVMLE-DGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQR 370
Score = 49.3 bits (116), Expect = 1e-05
Identities = 25/70 (35%), Positives = 39/70 (55%)
Query: 655 IFVRNLPFDFTWKMLKDKFNECGHVLYADIKMENGKSKGCGVVKFESPEVAERACRMMNG 714
+F++NL K L D F+ G++L + + SKG V FE+ E A++A MNG
Sbjct: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNG 160
Query: 715 MKLSGREIDV 724
M L+ R++ V
Sbjct: 161 MLLNDRKVFV 170
Score = 48.9 bits (115), Expect = 2e-05
Identities = 36/112 (32%), Positives = 55/112 (49%), Gaps = 7/112 (6%)
Query: 620 DRAIEMERG---NFGGSFAGSFGGAGGHAPGVARKACQ---IFVRNLPFDFTWKMLKDKF 673
D+AIE G N F G F + KA + ++++N + + LK+ F
Sbjct: 152 DKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLKELF 211
Query: 674 NECGHVLYADIKME-NGKSKGCGVVKFESPEVAERACRMMNGMKLSGREIDV 724
++ G L + + NGKSKG G V +E E A +A MNG ++SG+ I V
Sbjct: 212 SQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFV 263
Score = 46.6 bits (109), Expect = 8e-05
Identities = 23/72 (31%), Positives = 41/72 (56%)
Query: 655 IFVRNLPFDFTWKMLKDKFNECGHVLYADIKMENGKSKGCGVVKFESPEVAERACRMMNG 714
++++NL + L+ +F+ G + A + +E+G+SKG G V F SPE A +A MNG
Sbjct: 296 LYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNG 355
Query: 715 MKLSGREIDVRI 726
+ + + V +
Sbjct: 356 RIVGSKPLYVAL 367
Score = 44.3 bits (103), Expect = 4e-04
Identities = 27/71 (38%), Positives = 39/71 (54%), Gaps = 1/71 (1%)
Query: 206 VFVANLDYKVGWKKLKEVFSMAGVVVRADILEDKDGKSRGIGTVTFEQSIEAVQAISMFN 265
VF+ NLD + K L + FS G ++ ++ D++G S+G V FE A +AI N
Sbjct: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENG-SKGYAFVHFETQEAADKAIEKMN 159
Query: 266 GQLLFDRPMHV 276
G LL DR + V
Sbjct: 160 GMLLNDRKVFV 170
>gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo
sapiens]
Length = 644
Score = 70.9 bits (172), Expect = 4e-12
Identities = 61/240 (25%), Positives = 108/240 (45%), Gaps = 48/240 (20%)
Query: 47 EKRKEKNIKRGGNRFEPYANPTKRYRAFITNIPFDVKWQSLKDLVKEKVGEVTYVELLMD 106
+ RKE+ + G E + N +I N +V +SLK+L + G+ V+++ D
Sbjct: 174 KSRKEREAELGAKAKE-FTN------VYIKNFGEEVDDESLKELFSQ-FGKTLSVKVMRD 225
Query: 107 AEGKSRGCAVVEFKMEESMKKAAEVLNKHSLSGRPLKV-----KEDPDGEHARRAMQKVM 161
GKS+G V ++ E KA E +N +SG+ + V K + E R+ Q
Sbjct: 226 PNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQ--- 282
Query: 162 ATTGGMGMGPGGPGMITIPPSILNNPNIPNEIIHALQAGRLGSTVFVANLDYKVGWKKLK 221
+ E I Q G +++ NLD + +KL+
Sbjct: 283 ---------------------------LKQERISRYQ----GVNLYIKNLDDTIDDEKLR 311
Query: 222 EVFSMAGVVVRADILEDKDGKSRGIGTVTFEQSIEAVQAISMFNGQLLFDRPMHVKMDER 281
+ FS G + A ++ + DG+S+G G V F EA +A++ NG+++ +P++V + +R
Sbjct: 312 KEFSPFGSITSAKVMLE-DGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQR 370
Score = 49.3 bits (116), Expect = 1e-05
Identities = 25/70 (35%), Positives = 39/70 (55%)
Query: 655 IFVRNLPFDFTWKMLKDKFNECGHVLYADIKMENGKSKGCGVVKFESPEVAERACRMMNG 714
+F++NL K L D F+ G++L + + SKG V FE+ E A++A MNG
Sbjct: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNG 160
Query: 715 MKLSGREIDV 724
M L+ R++ V
Sbjct: 161 MLLNDRKVFV 170
Score = 48.9 bits (115), Expect = 2e-05
Identities = 36/112 (32%), Positives = 55/112 (49%), Gaps = 7/112 (6%)
Query: 620 DRAIEMERG---NFGGSFAGSFGGAGGHAPGVARKACQ---IFVRNLPFDFTWKMLKDKF 673
D+AIE G N F G F + KA + ++++N + + LK+ F
Sbjct: 152 DKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLKELF 211
Query: 674 NECGHVLYADIKME-NGKSKGCGVVKFESPEVAERACRMMNGMKLSGREIDV 724
++ G L + + NGKSKG G V +E E A +A MNG ++SG+ I V
Sbjct: 212 SQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFV 263
Score = 46.6 bits (109), Expect = 8e-05
Identities = 23/72 (31%), Positives = 41/72 (56%)
Query: 655 IFVRNLPFDFTWKMLKDKFNECGHVLYADIKMENGKSKGCGVVKFESPEVAERACRMMNG 714
++++NL + L+ +F+ G + A + +E+G+SKG G V F SPE A +A MNG
Sbjct: 296 LYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNG 355
Query: 715 MKLSGREIDVRI 726
+ + + V +
Sbjct: 356 RIVGSKPLYVAL 367
Score = 44.3 bits (103), Expect = 4e-04
Identities = 27/71 (38%), Positives = 39/71 (54%), Gaps = 1/71 (1%)
Query: 206 VFVANLDYKVGWKKLKEVFSMAGVVVRADILEDKDGKSRGIGTVTFEQSIEAVQAISMFN 265
VF+ NLD + K L + FS G ++ ++ D++G S+G V FE A +AI N
Sbjct: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENG-SKGYAFVHFETQEAADKAIEKMN 159
Query: 266 GQLLFDRPMHV 276
G LL DR + V
Sbjct: 160 GMLLNDRKVFV 170
>gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Homo
sapiens]
Length = 660
Score = 70.9 bits (172), Expect = 4e-12
Identities = 61/240 (25%), Positives = 108/240 (45%), Gaps = 48/240 (20%)
Query: 47 EKRKEKNIKRGGNRFEPYANPTKRYRAFITNIPFDVKWQSLKDLVKEKVGEVTYVELLMD 106
+ RKE+ + G E + N +I N +V +SLK+L + G+ V+++ D
Sbjct: 174 KSRKEREAELGAKAKE-FTN------VYIKNFGEEVDDESLKELFSQ-FGKTLSVKVMRD 225
Query: 107 AEGKSRGCAVVEFKMEESMKKAAEVLNKHSLSGRPLKV-----KEDPDGEHARRAMQKVM 161
GKS+G V ++ E KA E +N +SG+ + V K + E R+ Q
Sbjct: 226 PNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQ--- 282
Query: 162 ATTGGMGMGPGGPGMITIPPSILNNPNIPNEIIHALQAGRLGSTVFVANLDYKVGWKKLK 221
+ E I Q G +++ NLD + +KL+
Sbjct: 283 ---------------------------LKQERISRYQ----GVNLYIKNLDDTIDDEKLR 311
Query: 222 EVFSMAGVVVRADILEDKDGKSRGIGTVTFEQSIEAVQAISMFNGQLLFDRPMHVKMDER 281
+ FS G + A ++ + DG+S+G G V F EA +A++ NG+++ +P++V + +R
Sbjct: 312 KEFSPFGSITSAKVMLE-DGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQR 370
Score = 49.3 bits (116), Expect = 1e-05
Identities = 25/70 (35%), Positives = 39/70 (55%)
Query: 655 IFVRNLPFDFTWKMLKDKFNECGHVLYADIKMENGKSKGCGVVKFESPEVAERACRMMNG 714
+F++NL K L D F+ G++L + + SKG V FE+ E A++A MNG
Sbjct: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNG 160
Query: 715 MKLSGREIDV 724
M L+ R++ V
Sbjct: 161 MLLNDRKVFV 170
Score = 48.9 bits (115), Expect = 2e-05
Identities = 36/112 (32%), Positives = 55/112 (49%), Gaps = 7/112 (6%)
Query: 620 DRAIEMERG---NFGGSFAGSFGGAGGHAPGVARKACQ---IFVRNLPFDFTWKMLKDKF 673
D+AIE G N F G F + KA + ++++N + + LK+ F
Sbjct: 152 DKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLKELF 211
Query: 674 NECGHVLYADIKME-NGKSKGCGVVKFESPEVAERACRMMNGMKLSGREIDV 724
++ G L + + NGKSKG G V +E E A +A MNG ++SG+ I V
Sbjct: 212 SQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFV 263
Score = 46.6 bits (109), Expect = 8e-05
Identities = 23/72 (31%), Positives = 41/72 (56%)
Query: 655 IFVRNLPFDFTWKMLKDKFNECGHVLYADIKMENGKSKGCGVVKFESPEVAERACRMMNG 714
++++NL + L+ +F+ G + A + +E+G+SKG G V F SPE A +A MNG
Sbjct: 296 LYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNG 355
Query: 715 MKLSGREIDVRI 726
+ + + V +
Sbjct: 356 RIVGSKPLYVAL 367
Score = 44.3 bits (103), Expect = 4e-04
Identities = 27/71 (38%), Positives = 39/71 (54%), Gaps = 1/71 (1%)
Query: 206 VFVANLDYKVGWKKLKEVFSMAGVVVRADILEDKDGKSRGIGTVTFEQSIEAVQAISMFN 265
VF+ NLD + K L + FS G ++ ++ D++G S+G V FE A +AI N
Sbjct: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENG-SKGYAFVHFETQEAADKAIEKMN 159
Query: 266 GQLLFDRPMHV 276
G LL DR + V
Sbjct: 160 GMLLNDRKVFV 170
>gi|5803036 heterogeneous nuclear ribonucleoprotein A0 [Homo
sapiens]
Length = 305
Score = 70.5 bits (171), Expect = 5e-12
Identities = 71/211 (33%), Positives = 89/211 (42%), Gaps = 13/211 (6%)
Query: 206 VFVANLDYKVGWKKLKEVFSMAGVVVRADILEDKD-GKSRGIGTVTFEQSIEAVQAISMF 264
+FV L V L E FS G V +A+I+ DK GK RG G V F Q+ +A ++
Sbjct: 100 LFVGGLKGDVAEGDLIEHFSQFGTVEKAEIIADKQSGKKRGFGFVYF-QNHDAADKAAVV 158
Query: 265 NGQLLFDRPMHVKMDERALPKGDFFPPERPQQLPHGLGGIGMGLGPGGQPIDANHLNKGI 324
+ + VK +A+PK D + GG G G G GG D N L+KG
Sbjct: 159 KFHPIQGHRVEVK---KAVPKEDIYSGGGGGGSRSSRGGRG-GRGRGGGR-DQNGLSKGG 213
Query: 325 GMGNIGPAGMGMEGIGFGINKMGGMEGPFGGGMENMGRFGSGMNMGRINEILSNALKRGE 384
G G G G G G G N GG GGG + G G G + G
Sbjct: 214 GGGYNSYGGYGGGG-GGGYNAYGG-----GGGGSSYGGSDYGNGFGGFGSYSQHQSSYGP 267
Query: 385 IIAKQGGGGGGGSVPGIERMGPGIDRLGGAG 415
+ + GGGGGG S G GP GG G
Sbjct: 268 MKSGGGGGGGGSSWGGRSNSGPYRGGYGGGG 298
Score = 34.7 bits (78), Expect = 0.32
Identities = 23/82 (28%), Positives = 43/82 (52%), Gaps = 3/82 (3%)
Query: 646 PGVARKACQIFVRNLPFDFTWKMLKDKFNECGHVLYADI--KMENGKSKGCGVVKFESPE 703
PG K ++FV L D L + F++ G V A+I ++GK +G G V F++ +
Sbjct: 91 PGAHAKVKKLFVGGLKGDVAEGDLIEHFSQFGTVEKAEIIADKQSGKKRGFGFVYFQNHD 150
Query: 704 VAERACRMMNGMKLSGREIDVR 725
A++A ++ + G ++V+
Sbjct: 151 AADKAA-VVKFHPIQGHRVEVK 171
Score = 33.9 bits (76), Expect = 0.55
Identities = 20/63 (31%), Positives = 26/63 (41%), Gaps = 7/63 (11%)
Query: 585 GANSLERMGPAMGPALGAGIERMGLAMGGGGGASFDRAIEMERGNFGGSFAGSFGGAGGH 644
G S G G G G ++ GL+ GGGGG + G +GG G + GG
Sbjct: 185 GGGSRSSRGGRGGRGRGGGRDQNGLSKGGGGGYN-------SYGGYGGGGGGGYNAYGGG 237
Query: 645 APG 647
G
Sbjct: 238 GGG 240
Score = 30.0 bits (66), Expect = 8.0
Identities = 26/85 (30%), Positives = 42/85 (49%), Gaps = 13/85 (15%)
Query: 89 DLVKE--KVGEVTYVELLMDAE-GKSRGCAVVEFKMEESMKKAAEVLNKHSLSGRPLKVK 145
DL++ + G V E++ D + GK RG V F+ ++ KAA V+ H + G ++VK
Sbjct: 113 DLIEHFSQFGTVEKAEIIADKQSGKKRGFGFVYFQNHDAADKAA-VVKFHPIQGHRVEVK 171
Query: 146 EDPDGEHARRAMQKVMATTGGMGMG 170
+A+ K +GG G G
Sbjct: 172 ---------KAVPKEDIYSGGGGGG 187
>gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens]
Length = 631
Score = 69.7 bits (169), Expect = 9e-12
Identities = 64/253 (25%), Positives = 113/253 (44%), Gaps = 38/253 (15%)
Query: 45 QNEKRKEKNIKRGGNRFEPYANPTKRYRAFITNIPFDVKWQSLKDLVKEKVGEVTYVELL 104
Q + RKE+ + G R + + N +I N D+ + LKDL K G V+++
Sbjct: 172 QFKSRKEREAELGA-RAKEFPN------VYIKNFGEDMDDERLKDLFG-KFGPALSVKVM 223
Query: 105 MDAEGKSRGCAVVEFKMEESMKKAAEVLNKHSLSGRPLKVKEDPDGEHARRAMQKVMATT 164
D GKS+G V F+ E +KA + +N L+G+ + V RA +KV T
Sbjct: 224 TDESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVG---------RAQKKVERQT 274
Query: 165 GGMGMGPGGPGMITIPPSILNNPNIPNEIIHALQAGRLGSTVFVANLDYKVGWKKLKEVF 224
+ + I Q L +V NLD + ++L++ F
Sbjct: 275 ----------------ELKRTFEQMKQDRITRYQVVNL----YVKNLDDGIDDERLRKAF 314
Query: 225 SMAGVVVRADILEDKDGKSRGIGTVTFEQSIEAVQAISMFNGQLLFDRPMHVKMDERALP 284
S G + A ++ + G+S+G G V F EA +A++ NG+++ +P++V + +R
Sbjct: 315 SPFGTITSAKVMME-GGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQRKEE 373
Query: 285 KGDFFPPERPQQL 297
+ + E Q++
Sbjct: 374 RQAYLTNEYMQRM 386
Score = 56.2 bits (134), Expect = 1e-07
Identities = 30/70 (42%), Positives = 42/70 (60%)
Query: 655 IFVRNLPFDFTWKMLKDKFNECGHVLYADIKMENGKSKGCGVVKFESPEVAERACRMMNG 714
IFV+NL K L D + G++L ++ + SKG G V FE+ E AERA + MNG
Sbjct: 101 IFVKNLDKSINNKALYDTVSAFGNILSCNVVCDENGSKGYGFVHFETHEAAERAIKKMNG 160
Query: 715 MKLSGREIDV 724
M L+GR++ V
Sbjct: 161 MLLNGRKVFV 170
Score = 50.8 bits (120), Expect = 4e-06
Identities = 29/77 (37%), Positives = 45/77 (58%), Gaps = 1/77 (1%)
Query: 649 ARKACQIFVRNLPFDFTWKMLKDKFNECGHVLYADIKM-ENGKSKGCGVVKFESPEVAER 707
A++ ++++N D + LKD F + G L + E+GKSKG G V FE E A++
Sbjct: 187 AKEFPNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQK 246
Query: 708 ACRMMNGMKLSGREIDV 724
A MNG +L+G++I V
Sbjct: 247 AVDEMNGKELNGKQIYV 263
Score = 46.2 bits (108), Expect = 1e-04
Identities = 25/72 (34%), Positives = 40/72 (55%)
Query: 655 IFVRNLPFDFTWKMLKDKFNECGHVLYADIKMENGKSKGCGVVKFESPEVAERACRMMNG 714
++V+NL + L+ F+ G + A + ME G+SKG G V F SPE A +A MNG
Sbjct: 296 LYVKNLDDGIDDERLRKAFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNG 355
Query: 715 MKLSGREIDVRI 726
++ + + V +
Sbjct: 356 RIVATKPLYVAL 367
Score = 42.4 bits (98), Expect = 0.002
Identities = 26/71 (36%), Positives = 39/71 (54%), Gaps = 1/71 (1%)
Query: 206 VFVANLDYKVGWKKLKEVFSMAGVVVRADILEDKDGKSRGIGTVTFEQSIEAVQAISMFN 265
+FV NLD + K L + S G ++ +++ D++G S+G G V FE A +AI N
Sbjct: 101 IFVKNLDKSINNKALYDTVSAFGNILSCNVVCDENG-SKGYGFVHFETHEAAERAIKKMN 159
Query: 266 GQLLFDRPMHV 276
G LL R + V
Sbjct: 160 GMLLNGRKVFV 170
>gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens]
Length = 636
Score = 69.3 bits (168), Expect = 1e-11
Identities = 61/235 (25%), Positives = 107/235 (45%), Gaps = 38/235 (16%)
Query: 47 EKRKEKNIKRGGNRFEPYANPTKRYRAFITNIPFDVKWQSLKDLVKEKVGEVTYVELLMD 106
+ RKE+ + G R + + N +I N D+ + LKDL K G V+++ D
Sbjct: 174 KSRKEREAELGA-RAKEFTN------VYIKNFGEDMDDERLKDLFG-KFGPALSVKVMTD 225
Query: 107 AEGKSRGCAVVEFKMEESMKKAAEVLNKHSLSGRPLKVKEDPDGEHARRAMQKVMATTGG 166
GKS+G V F+ E +KA + +N L+G+ + V RA +KV T
Sbjct: 226 ESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVG---------RAQKKVERQT-- 274
Query: 167 MGMGPGGPGMITIPPSILNNPNIPNEIIHALQAGRLGSTVFVANLDYKVGWKKLKEVFSM 226
+ + I Q G ++V NLD + ++L++ FS
Sbjct: 275 --------------ELKRKFEQMKQDRITRYQ----GVNLYVKNLDDGIDDERLRKEFSP 316
Query: 227 AGVVVRADILEDKDGKSRGIGTVTFEQSIEAVQAISMFNGQLLFDRPMHVKMDER 281
G + A ++ + G+S+G G V F EA +A++ NG+++ +P++V + +R
Sbjct: 317 FGTITSAKVMME-GGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQR 370
Score = 54.3 bits (129), Expect = 4e-07
Identities = 29/70 (41%), Positives = 40/70 (57%)
Query: 655 IFVRNLPFDFTWKMLKDKFNECGHVLYADIKMENGKSKGCGVVKFESPEVAERACRMMNG 714
IF++NL K L D F+ G++L + + SKG G V FE+ E AERA MNG
Sbjct: 101 IFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNG 160
Query: 715 MKLSGREIDV 724
M L+ R++ V
Sbjct: 161 MLLNDRKVFV 170
Score = 51.6 bits (122), Expect = 3e-06
Identities = 29/77 (37%), Positives = 45/77 (58%), Gaps = 1/77 (1%)
Query: 649 ARKACQIFVRNLPFDFTWKMLKDKFNECGHVLYADIKM-ENGKSKGCGVVKFESPEVAER 707
A++ ++++N D + LKD F + G L + E+GKSKG G V FE E A++
Sbjct: 187 AKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQK 246
Query: 708 ACRMMNGMKLSGREIDV 724
A MNG +L+G++I V
Sbjct: 247 AVDEMNGKELNGKQIYV 263
Score = 47.0 bits (110), Expect = 6e-05
Identities = 25/72 (34%), Positives = 41/72 (56%)
Query: 655 IFVRNLPFDFTWKMLKDKFNECGHVLYADIKMENGKSKGCGVVKFESPEVAERACRMMNG 714
++V+NL + L+ +F+ G + A + ME G+SKG G V F SPE A +A MNG
Sbjct: 296 LYVKNLDDGIDDERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNG 355
Query: 715 MKLSGREIDVRI 726
++ + + V +
Sbjct: 356 RIVATKPLYVAL 367
Score = 46.6 bits (109), Expect = 8e-05
Identities = 27/71 (38%), Positives = 40/71 (56%), Gaps = 1/71 (1%)
Query: 206 VFVANLDYKVGWKKLKEVFSMAGVVVRADILEDKDGKSRGIGTVTFEQSIEAVQAISMFN 265
+F+ NLD + K L + FS G ++ ++ D++G S+G G V FE A +AI N
Sbjct: 101 IFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENG-SKGYGFVHFETQEAAERAIEKMN 159
Query: 266 GQLLFDRPMHV 276
G LL DR + V
Sbjct: 160 GMLLNDRKVFV 170
>gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens]
Length = 589
Score = 59.7 bits (143), Expect = 9e-09
Identities = 91/333 (27%), Positives = 124/333 (37%), Gaps = 52/333 (15%)
Query: 204 STVFVANLDYKVGWKKLKEVFSMAGVVVR--------ADILEDKD-GKSRGIGTVTFEQS 254
+T+FV L V ++ E F G++ ++ DKD GK +G TV+F+
Sbjct: 231 NTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDP 290
Query: 255 IEAVQAISMFNGQLLFDRPMHVKMDERALPKGDFFPPERPQQLPHGLGGI---GMGLGPG 311
A AI F+G+ + V R + +F G GG G G G
Sbjct: 291 PSAKAAIDWFDGKEFHGNIIKVSFATR---RPEFMRGGGSGGGRRGRGGYRGRGGFQGRG 347
Query: 312 GQPIDANHLNKGIGMGNIG-------------------PAGMGMEGIGFGINK------- 345
G P + + GN+ P+G G G+G +
Sbjct: 348 GDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGG 407
Query: 346 MGGMEGPFGGGMENMGRFGSGMNMGRINEILSNALKRGEIIAKQGGGGGGGSVPGIERMG 405
GG G +GG G G + G + S G+ GG GG G G
Sbjct: 408 RGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGG 467
Query: 406 PGIDRLGGAGMERMG----AGLGHGMDRVGSEIERMGLVMDRMG-SVERMGSGIER-MGP 459
G DR GG G +R G G G+G DR G +R G DR G +R G G +R G
Sbjct: 468 YGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGG 527
Query: 460 LGLDHMASSIERMGQTMERIGS-GVERMGAGMG 491
G D S G +R G G +R G G G
Sbjct: 528 YGGDRGGGS----GYGGDRSGGYGGDRSGGGYG 556
Score = 43.1 bits (100), Expect = 0.001
Identities = 51/153 (33%), Positives = 61/153 (39%), Gaps = 20/153 (13%)
Query: 300 GLGGIGMGLGPGGQPIDANHLNKGIGMGNIGPAGMGMEGIGFGINKMGGMEGPFGG-GME 358
G GG G G GG ++G G G G G + G+G ++ GG G GG G +
Sbjct: 442 GYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGD 501
Query: 359 NMGRFGSGMNMGRINEILSNALKRGEIIAKQGGGGGGGSVPGIERMGPGIDRLGGAGMER 418
G G G RG GG GGGS G G DR GG G +R
Sbjct: 502 RGGYGGDRGGYGGDRGGYGGDRSRG----GYGGDRGGGS-------GYGGDRSGGYGGDR 550
Query: 419 MGAGLGHGMDRVGSEIERMGLVMDRMGSVERMG 451
G G+G DR G G DR G +MG
Sbjct: 551 SGG--GYGGDRGG------GYGGDRGGYGGKMG 575
>gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens]
Length = 592
Score = 59.7 bits (143), Expect = 9e-09
Identities = 91/333 (27%), Positives = 124/333 (37%), Gaps = 52/333 (15%)
Query: 204 STVFVANLDYKVGWKKLKEVFSMAGVVVR--------ADILEDKD-GKSRGIGTVTFEQS 254
+T+FV L V ++ E F G++ ++ DKD GK +G TV+F+
Sbjct: 234 NTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDP 293
Query: 255 IEAVQAISMFNGQLLFDRPMHVKMDERALPKGDFFPPERPQQLPHGLGGI---GMGLGPG 311
A AI F+G+ + V R + +F G GG G G G
Sbjct: 294 PSAKAAIDWFDGKEFHGNIIKVSFATR---RPEFMRGGGSGGGRRGRGGYRGRGGFQGRG 350
Query: 312 GQPIDANHLNKGIGMGNIG-------------------PAGMGMEGIGFGINK------- 345
G P + + GN+ P+G G G+G +
Sbjct: 351 GDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGG 410
Query: 346 MGGMEGPFGGGMENMGRFGSGMNMGRINEILSNALKRGEIIAKQGGGGGGGSVPGIERMG 405
GG G +GG G G + G + S G+ GG GG G G
Sbjct: 411 RGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGG 470
Query: 406 PGIDRLGGAGMERMG----AGLGHGMDRVGSEIERMGLVMDRMG-SVERMGSGIER-MGP 459
G DR GG G +R G G G+G DR G +R G DR G +R G G +R G
Sbjct: 471 YGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGG 530
Query: 460 LGLDHMASSIERMGQTMERIGS-GVERMGAGMG 491
G D S G +R G G +R G G G
Sbjct: 531 YGGDRGGGS----GYGGDRSGGYGGDRSGGGYG 559
Score = 43.1 bits (100), Expect = 0.001
Identities = 51/153 (33%), Positives = 61/153 (39%), Gaps = 20/153 (13%)
Query: 300 GLGGIGMGLGPGGQPIDANHLNKGIGMGNIGPAGMGMEGIGFGINKMGGMEGPFGG-GME 358
G GG G G GG ++G G G G G + G+G ++ GG G GG G +
Sbjct: 445 GYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGD 504
Query: 359 NMGRFGSGMNMGRINEILSNALKRGEIIAKQGGGGGGGSVPGIERMGPGIDRLGGAGMER 418
G G G RG GG GGGS G G DR GG G +R
Sbjct: 505 RGGYGGDRGGYGGDRGGYGGDRSRG----GYGGDRGGGS-------GYGGDRSGGYGGDR 553
Query: 419 MGAGLGHGMDRVGSEIERMGLVMDRMGSVERMG 451
G G+G DR G G DR G +MG
Sbjct: 554 SGG--GYGGDRGG------GYGGDRGGYGGKMG 578
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 58.9 bits (141), Expect = 2e-08
Identities = 40/128 (31%), Positives = 62/128 (48%), Gaps = 11/128 (8%)
Query: 33 APGPKGEGERPAQNEKRKEKNIKRGGNRFEPYANPTK-RYRAFITNIPFDVKWQSLKDLV 91
A GP+ +G + R +R G + Y PT+ YR + N+ WQ LKD +
Sbjct: 70 ARGPRRDG---SYGSGRSGYGYRRSGR--DKYGPPTRTEYRLIVENLSSRCSWQDLKDYM 124
Query: 92 KEKVGEVTYVELLMDAEGKSRGCAVVEFKMEESMKKAAEVLNKHSLSGRPLKVKEDPDGE 151
++ GEVTY DA + V+EF MK+A E L+ ++GR +++ ED G
Sbjct: 125 RQ-AGEVTYA----DAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGS 179
Query: 152 HARRAMQK 159
RR+ +
Sbjct: 180 RRRRSYSR 187
Score = 42.4 bits (98), Expect = 0.002
Identities = 31/103 (30%), Positives = 49/103 (47%), Gaps = 9/103 (8%)
Query: 632 GSFAGSFGGAGGHAPG------VARKACQIFVRNLPFDFTWKMLKDKFNECGHVLYADIK 685
GS+ G G G R ++ V NL +W+ LKD + G V YAD
Sbjct: 77 GSYGSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLSSRCSWQDLKDYMRQAGEVTYAD-- 134
Query: 686 MENGKSKGCGVVKFESPEVAERACRMMNGMKLSGREIDVRIDR 728
G+ K GV++F S +RA ++G +++GR+I + D+
Sbjct: 135 AHKGR-KNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDK 176
>gi|253970502 Ewing sarcoma breakpoint region 1 isoform 3 [Homo
sapiens]
Length = 655
Score = 55.8 bits (133), Expect = 1e-07
Identities = 88/316 (27%), Positives = 116/316 (36%), Gaps = 57/316 (18%)
Query: 165 GGMGMG-------PGGPGMITIPPSILNNPNIPNEIIHALQAGRLGSTVFVANLDYKVGW 217
GGMG G PGGP M P L P P+E S ++V L+ V
Sbjct: 322 GGMGAGERGGFNKPGGP-MDEGPDLDLGPPVDPDEDSD-------NSAIYVQGLNDSVTL 373
Query: 218 KKLKEVFSMAGVVVRAD---------ILEDKDGKSRGIGTVTFEQSIEAVQAISMFNGQL 268
L + F GVV L+ + GK +G TV++E A A+ F+G+
Sbjct: 374 DDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKD 433
Query: 269 LFDRPMHVKMDERALPKGDF---FPPERPQQLPHGL-GGIGMGLGPGGQPIDANHLNKGI 324
+ V + + P PP + +P L GG G GPGG
Sbjct: 434 FQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGP----------- 482
Query: 325 GMGNIGPAGMGMEGIGFGINKMGGMEGPFGGGMENMGRFGSGM--NMGRINEILSNALKR 382
MG +G G G + GF G G GG R G N G N+ + +
Sbjct: 483 -MGRMG--GRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTEC 539
Query: 383 GEIIAKQG-----------GGGGGGSVPGIERMGPG--IDRLGGAGMERMGAGLGHGMDR 429
+ A + GG G PG R G G +DR G GM R G G G R
Sbjct: 540 NQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFR 599
Query: 430 VGSEIERMGLVMDRMG 445
G ++R G R G
Sbjct: 600 GGRGMDRGGFGGGRRG 615
Score = 47.8 bits (112), Expect = 4e-05
Identities = 47/181 (25%), Positives = 62/181 (34%), Gaps = 33/181 (18%)
Query: 571 MGANSLERMGLERMGANSLERMGPAMGPALGAGIERMGLAMGGGGGASFDRAIEMERGNF 630
MG E G G N GP G +R G++ GG GG RG
Sbjct: 275 MGVYGQESGGFSGPGENR-SMSGPDNRGRGRGGFDRGGMSRGGRGGG---------RGGM 324
Query: 631 GGSFAGSFGGAGGHA-------------PGVARKACQIFVRNLPFDFTWKMLKDKFNECG 677
G G F GG P I+V+ L T L D F +CG
Sbjct: 325 GAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCG 384
Query: 678 HV----------LYADIKMENGKSKGCGVVKFESPEVAERACRMMNGMKLSGREIDVRID 727
V ++ + E GK KG V +E P A+ A +G G ++ V +
Sbjct: 385 VVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLA 444
Query: 728 R 728
R
Sbjct: 445 R 445
Score = 34.3 bits (77), Expect = 0.42
Identities = 30/83 (36%), Positives = 37/83 (44%), Gaps = 5/83 (6%)
Query: 284 PKGDFFPPERPQQLPHGLGGIGMGLGPGGQPIDANH---LNKGIGMGNIGP--AGMGMEG 338
P+G PP P G GG G G G +D + +G G+ G G GM+
Sbjct: 547 PEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDR 606
Query: 339 IGFGINKMGGMEGPFGGGMENMG 361
GFG + GG GP G ME MG
Sbjct: 607 GGFGGGRRGGPGGPPGPLMEQMG 629
>gi|253970500 Ewing sarcoma breakpoint region 1 isoform 1 [Homo
sapiens]
Length = 661
Score = 55.8 bits (133), Expect = 1e-07
Identities = 88/316 (27%), Positives = 116/316 (36%), Gaps = 57/316 (18%)
Query: 165 GGMGMG-------PGGPGMITIPPSILNNPNIPNEIIHALQAGRLGSTVFVANLDYKVGW 217
GGMG G PGGP M P L P P+E S ++V L+ V
Sbjct: 328 GGMGAGERGGFNKPGGP-MDEGPDLDLGPPVDPDEDSD-------NSAIYVQGLNDSVTL 379
Query: 218 KKLKEVFSMAGVVVRAD---------ILEDKDGKSRGIGTVTFEQSIEAVQAISMFNGQL 268
L + F GVV L+ + GK +G TV++E A A+ F+G+
Sbjct: 380 DDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKD 439
Query: 269 LFDRPMHVKMDERALPKGDF---FPPERPQQLPHGL-GGIGMGLGPGGQPIDANHLNKGI 324
+ V + + P PP + +P L GG G GPGG
Sbjct: 440 FQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGP----------- 488
Query: 325 GMGNIGPAGMGMEGIGFGINKMGGMEGPFGGGMENMGRFGSGM--NMGRINEILSNALKR 382
MG +G G G + GF G G GG R G N G N+ + +
Sbjct: 489 -MGRMG--GRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTEC 545
Query: 383 GEIIAKQG-----------GGGGGGSVPGIERMGPG--IDRLGGAGMERMGAGLGHGMDR 429
+ A + GG G PG R G G +DR G GM R G G G R
Sbjct: 546 NQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFR 605
Query: 430 VGSEIERMGLVMDRMG 445
G ++R G R G
Sbjct: 606 GGRGMDRGGFGGGRRG 621
Score = 47.8 bits (112), Expect = 4e-05
Identities = 47/181 (25%), Positives = 62/181 (34%), Gaps = 33/181 (18%)
Query: 571 MGANSLERMGLERMGANSLERMGPAMGPALGAGIERMGLAMGGGGGASFDRAIEMERGNF 630
MG E G G N GP G +R G++ GG GG RG
Sbjct: 281 MGVYGQESGGFSGPGENR-SMSGPDNRGRGRGGFDRGGMSRGGRGGG---------RGGM 330
Query: 631 GGSFAGSFGGAGGHA-------------PGVARKACQIFVRNLPFDFTWKMLKDKFNECG 677
G G F GG P I+V+ L T L D F +CG
Sbjct: 331 GAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCG 390
Query: 678 HV----------LYADIKMENGKSKGCGVVKFESPEVAERACRMMNGMKLSGREIDVRID 727
V ++ + E GK KG V +E P A+ A +G G ++ V +
Sbjct: 391 VVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLA 450
Query: 728 R 728
R
Sbjct: 451 R 451
Score = 34.3 bits (77), Expect = 0.42
Identities = 30/83 (36%), Positives = 37/83 (44%), Gaps = 5/83 (6%)
Query: 284 PKGDFFPPERPQQLPHGLGGIGMGLGPGGQPIDANH---LNKGIGMGNIGP--AGMGMEG 338
P+G PP P G GG G G G +D + +G G+ G G GM+
Sbjct: 553 PEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDR 612
Query: 339 IGFGINKMGGMEGPFGGGMENMG 361
GFG + GG GP G ME MG
Sbjct: 613 GGFGGGRRGGPGGPPGPLMEQMG 635
>gi|9994185 RNA binding motif protein 7 [Homo sapiens]
Length = 266
Score = 55.8 bits (133), Expect = 1e-07
Identities = 28/79 (35%), Positives = 45/79 (56%)
Query: 199 AGRLGSTVFVANLDYKVGWKKLKEVFSMAGVVVRADILEDKDGKSRGIGTVTFEQSIEAV 258
A T+FV NL+ KV + L E+F AG V++ I +DKDGK + V F+ +
Sbjct: 5 AAEADRTLFVGNLETKVTEELLFELFHQAGPVIKVKIPKDKDGKPKQFAFVNFKHEVSVP 64
Query: 259 QAISMFNGQLLFDRPMHVK 277
A+++ NG L+ RP+ ++
Sbjct: 65 YAMNLLNGIKLYGRPIKIQ 83
Score = 41.6 bits (96), Expect = 0.003
Identities = 27/80 (33%), Positives = 41/80 (51%), Gaps = 1/80 (1%)
Query: 74 FITNIPFDVKWQSLKDLVKEKVGEVTYVELLMDAEGKSRGCAVVEFKMEESMKKAAEVLN 133
F+ N+ V + L +L + G V V++ D +GK + A V FK E S+ A +LN
Sbjct: 13 FVGNLETKVTEELLFELFHQ-AGPVIKVKIPKDKDGKPKQFAFVNFKHEVSVPYAMNLLN 71
Query: 134 KHSLSGRPLKVKEDPDGEHA 153
L GRP+K++ HA
Sbjct: 72 GIKLYGRPIKIQFRSGSSHA 91
Score = 38.9 bits (89), Expect = 0.017
Identities = 24/72 (33%), Positives = 39/72 (54%), Gaps = 1/72 (1%)
Query: 655 IFVRNLPFDFTWKMLKDKFNECGHVLYADI-KMENGKSKGCGVVKFESPEVAERACRMMN 713
+FV NL T ++L + F++ G V+ I K ++GK K V F+ A ++N
Sbjct: 12 LFVGNLETKVTEELLFELFHQAGPVIKVKIPKDKDGKPKQFAFVNFKHEVSVPYAMNLLN 71
Query: 714 GMKLSGREIDVR 725
G+KL GR I ++
Sbjct: 72 GIKLYGRPIKIQ 83
>gi|4557493 cleavage stimulation factor subunit 2 [Homo sapiens]
Length = 577
Score = 55.5 bits (132), Expect = 2e-07
Identities = 33/87 (37%), Positives = 48/87 (55%), Gaps = 4/87 (4%)
Query: 646 PGVARKACQIFVRNLPFDFTWKMLKDKFNECGHVLYADI--KMENGKSKGCGVVKFESPE 703
P V R +FV N+P++ T + LKD F+E G V+ + E GK KG G +++ E
Sbjct: 9 PAVDRSLRSVFVGNIPYEATEEQLKDIFSEVGPVVSFRLVYDRETGKPKGYGFCEYQDQE 68
Query: 704 VAERACRMMNGMKLSGREIDVRIDRNA 730
A A R +NG + SGR + R+D A
Sbjct: 69 TALSAMRNLNGREFSGRAL--RVDNAA 93
Score = 46.2 bits (108), Expect = 1e-04
Identities = 113/513 (22%), Positives = 178/513 (34%), Gaps = 65/513 (12%)
Query: 74 FITNIPFDVKWQSLKDLVKEKVGEVTYVELLMDAE-GKSRGCAVVEFKMEESMKKAAEVL 132
F+ NIP++ + LKD+ E VG V L+ D E GK +G E++ +E+ A L
Sbjct: 19 FVGNIPYEATEEQLKDIFSE-VGPVVSFRLVYDRETGKPKGYGFCEYQDQETALSAMRNL 77
Query: 133 NKHSLSGRPLKVKEDPDGEHARRAMQKVMATTGGMGMGPGG-------------PGMITI 179
N SGR L+V D + K + T + P G + ++
Sbjct: 78 NGREFSGRALRV--DNAASEKNKEELKSLGTGAPVIESPYGETISPEDAPESISKAVASL 135
Query: 180 PPS------------ILNNPNIPNEII---HALQAGRLGSTVFVANLDYKVGWKKLKEVF 224
PP + N+P ++ L L + V + +D ++ K L
Sbjct: 136 PPEQMFELMKQMKLCVQNSPQEARNMLLQNPQLAYALLQAQVVMRIVDPEIALKILHRQT 195
Query: 225 SMAGVVVRADILEDKDGKSRGIGTVTFEQSIEAVQAISMFNGQLLFDRPMHVKMDERALP 284
++ ++ G G +Q+ +A QA S+ + P+ + +P
Sbjct: 196 NIPTLIAGNPQPVHGAGPGSGSNVSMNQQNPQAPQAQSLGGMHVNGAPPLMQASMQGGVP 255
Query: 285 KGDFFPPERPQQLPHGLGGIGMG-LGPGGQPIDANHLNKGIGMGNIGPAGMGMEGIGFGI 343
P Q+P + G G G L PGG + +GM GP M +
Sbjct: 256 --------APGQMPAAVTGPGPGSLAPGG------GMQAQVGMPGSGPVSMERGQVPMQD 301
Query: 344 NKMGGMEGPFGGGMEN-MGRFGSGMNMGRINEILS--NALKRGEIIAKQGGGGGGGSVPG 400
+ G + G G N R +LS ++ + G VPG
Sbjct: 302 PRAAMQRGSLPANVPTPRGLLGDAPNDPRGGTLLSVTGEVEPRGYLGPPHQGPPMHHVPG 361
Query: 401 IERMGPGIDRLGGAGMER----MGAGLGHGMDRVGSEIERMGLVMDRMGSVERMGSGIER 456
E GP L G + M G +D+ G ++ G R ++ G
Sbjct: 362 HESRGPPPHELRGGPLPEPRPLMAEPRGPMLDQRGPPLDGRGGRDPR--GIDARGMEARA 419
Query: 457 MGPLGLDHMASSIERM-GQTMERIGSGVERMGAGMGFGLERMAAPIDRVGQTIERMG--- 512
M GLD M + ME M A A +D G G
Sbjct: 420 MEARGLDARGLEARAMEARAMEARAMEARAMEARAMEVRGMEARGMDTRGPVPGPRGPIP 479
Query: 513 SGVERMGPAIERMGLSM---ERMVPAGMGAGLE 542
SG++ GP+ MG + R VP G G++
Sbjct: 480 SGMQ--GPSPINMGAVVPQGSRQVPVMQGTGMQ 510
Score = 42.7 bits (99), Expect = 0.001
Identities = 23/73 (31%), Positives = 41/73 (56%), Gaps = 1/73 (1%)
Query: 205 TVFVANLDYKVGWKKLKEVFSMAGVVVRADILEDKD-GKSRGIGTVTFEQSIEAVQAISM 263
+VFV N+ Y+ ++LK++FS G VV ++ D++ GK +G G ++ A+ A+
Sbjct: 17 SVFVGNIPYEATEEQLKDIFSEVGPVVSFRLVYDRETGKPKGYGFCEYQDQETALSAMRN 76
Query: 264 FNGQLLFDRPMHV 276
NG+ R + V
Sbjct: 77 LNGREFSGRALRV 89
>gi|226497734 RNA binding motif protein 19 [Homo sapiens]
Length = 960
Score = 54.7 bits (130), Expect = 3e-07
Identities = 28/83 (33%), Positives = 46/83 (55%), Gaps = 5/83 (6%)
Query: 653 CQIFVRNLPFDFTWKMLKDKFNECGHVLYADIKMENGK-----SKGCGVVKFESPEVAER 707
C +F++NL FD T + LK+ F++ G V I + K S G G V++ PE A++
Sbjct: 730 CTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVEYRKPEQAQK 789
Query: 708 ACRMMNGMKLSGREIDVRIDRNA 730
A + + G + G +++VRI A
Sbjct: 790 ALKQLQGHVVDGHKLEVRISERA 812
Score = 50.4 bits (119), Expect = 6e-06
Identities = 64/275 (23%), Positives = 111/275 (40%), Gaps = 40/275 (14%)
Query: 4 GVEAAAE-VAATEIKMEEESGAPGVPSGNGAPGPKGEGERPAQNEKRKEKNIKRGGNRFE 62
G EA E +AT + E +S G G A G K E A+ EK +
Sbjct: 239 GSEAEEEDSSATPVLQERDSKGAGQEQGMPA-GKKRPPEARAETEKPANQK--------- 288
Query: 63 PYANPTKRYRAFITNIPFDVKWQSLKDLVKEKVGEVTYVELLMDAEGKSRGCAVVEFKME 122
PT + + PF+V +++ + + + + ++ +A G G V+F E
Sbjct: 289 ---EPTTCHTVKLRGAPFNVTEKNVMEFLAPL--KPVAIRIVRNAHGNKTGYIFVDFSNE 343
Query: 123 ESMKKAAEVLNKHSLSGRPLKVKEDPDGEHARRAMQKVMATTGGMGMGPGGPGMITIPPS 182
E +K+A + N+ + GR ++V + + + A + + G +G
Sbjct: 344 EEVKQALKC-NREYMGGRYIEVFREKNVPTTKGAPKNTTKSWQGRILGEN---------- 392
Query: 183 ILNNPNIPNEIIHALQAGRLGSTVFVANLDYKVGWKKLKEVFSMAGVVVRADI-LEDKDG 241
E ++GRL FV NL Y + L+++FS G + ++
Sbjct: 393 --------EEEEDLAESGRL----FVRNLPYTSTEEDLEKLFSKYGPLSELHYPIDSLTK 440
Query: 242 KSRGIGTVTFEQSIEAVQAISMFNGQLLFDRPMHV 276
K +G +TF AV+A S +GQ+ R +HV
Sbjct: 441 KPKGFAFITFMFPEHAVKAYSEVDGQVFQGRMLHV 475
Score = 47.0 bits (110), Expect = 6e-05
Identities = 27/84 (32%), Positives = 44/84 (52%), Gaps = 4/84 (4%)
Query: 203 GSTVFVANLDYKVGWKKLKEVFSMAGVVVRADILEDKDGK----SRGIGTVTFEQSIEAV 258
G T+F+ NL++ +KLKEVFS G V I + K+ S G G V + + +A
Sbjct: 729 GCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVEYRKPEQAQ 788
Query: 259 QAISMFNGQLLFDRPMHVKMDERA 282
+A+ G ++ + V++ ERA
Sbjct: 789 KALKQLQGHVVDGHKLEVRISERA 812
Score = 36.6 bits (83), Expect = 0.085
Identities = 24/73 (32%), Positives = 38/73 (52%), Gaps = 2/73 (2%)
Query: 654 QIFVRNLPFDFTWKMLKDKFNECGHV--LYADIKMENGKSKGCGVVKFESPEVAERACRM 711
++FVRNLP+ T + L+ F++ G + L+ I K KG + F PE A +A
Sbjct: 403 RLFVRNLPYTSTEEDLEKLFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSE 462
Query: 712 MNGMKLSGREIDV 724
++G GR + V
Sbjct: 463 VDGQVFQGRMLHV 475
Score = 30.4 bits (67), Expect = 6.1
Identities = 19/63 (30%), Positives = 29/63 (46%), Gaps = 1/63 (1%)
Query: 72 RAFITNIPFDVKWQSLKDLVKEKVGEVTYVELLMDAEGKSRGCAVVEFKMEESMKKAAEV 131
R + N+P +K + + L G +T L +GK R + FK EE +KA +
Sbjct: 3 RLIVKNLPNGMKEERFRQLFAA-FGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQKH 61
Query: 132 LNK 134
NK
Sbjct: 62 FNK 64
>gi|226497654 RNA binding motif protein 19 [Homo sapiens]
Length = 960
Score = 54.7 bits (130), Expect = 3e-07
Identities = 28/83 (33%), Positives = 46/83 (55%), Gaps = 5/83 (6%)
Query: 653 CQIFVRNLPFDFTWKMLKDKFNECGHVLYADIKMENGK-----SKGCGVVKFESPEVAER 707
C +F++NL FD T + LK+ F++ G V I + K S G G V++ PE A++
Sbjct: 730 CTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVEYRKPEQAQK 789
Query: 708 ACRMMNGMKLSGREIDVRIDRNA 730
A + + G + G +++VRI A
Sbjct: 790 ALKQLQGHVVDGHKLEVRISERA 812
Score = 50.4 bits (119), Expect = 6e-06
Identities = 64/275 (23%), Positives = 111/275 (40%), Gaps = 40/275 (14%)
Query: 4 GVEAAAE-VAATEIKMEEESGAPGVPSGNGAPGPKGEGERPAQNEKRKEKNIKRGGNRFE 62
G EA E +AT + E +S G G A G K E A+ EK +
Sbjct: 239 GSEAEEEDSSATPVLQERDSKGAGQEQGMPA-GKKRPPEARAETEKPANQK--------- 288
Query: 63 PYANPTKRYRAFITNIPFDVKWQSLKDLVKEKVGEVTYVELLMDAEGKSRGCAVVEFKME 122
PT + + PF+V +++ + + + + ++ +A G G V+F E
Sbjct: 289 ---EPTTCHTVKLRGAPFNVTEKNVMEFLAPL--KPVAIRIVRNAHGNKTGYIFVDFSNE 343
Query: 123 ESMKKAAEVLNKHSLSGRPLKVKEDPDGEHARRAMQKVMATTGGMGMGPGGPGMITIPPS 182
E +K+A + N+ + GR ++V + + + A + + G +G
Sbjct: 344 EEVKQALKC-NREYMGGRYIEVFREKNVPTTKGAPKNTTKSWQGRILGEN---------- 392
Query: 183 ILNNPNIPNEIIHALQAGRLGSTVFVANLDYKVGWKKLKEVFSMAGVVVRADI-LEDKDG 241
E ++GRL FV NL Y + L+++FS G + ++
Sbjct: 393 --------EEEEDLAESGRL----FVRNLPYTSTEEDLEKLFSKYGPLSELHYPIDSLTK 440
Query: 242 KSRGIGTVTFEQSIEAVQAISMFNGQLLFDRPMHV 276
K +G +TF AV+A S +GQ+ R +HV
Sbjct: 441 KPKGFAFITFMFPEHAVKAYSEVDGQVFQGRMLHV 475
Score = 47.0 bits (110), Expect = 6e-05
Identities = 27/84 (32%), Positives = 44/84 (52%), Gaps = 4/84 (4%)
Query: 203 GSTVFVANLDYKVGWKKLKEVFSMAGVVVRADILEDKDGK----SRGIGTVTFEQSIEAV 258
G T+F+ NL++ +KLKEVFS G V I + K+ S G G V + + +A
Sbjct: 729 GCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVEYRKPEQAQ 788
Query: 259 QAISMFNGQLLFDRPMHVKMDERA 282
+A+ G ++ + V++ ERA
Sbjct: 789 KALKQLQGHVVDGHKLEVRISERA 812
Score = 36.6 bits (83), Expect = 0.085
Identities = 24/73 (32%), Positives = 38/73 (52%), Gaps = 2/73 (2%)
Query: 654 QIFVRNLPFDFTWKMLKDKFNECGHV--LYADIKMENGKSKGCGVVKFESPEVAERACRM 711
++FVRNLP+ T + L+ F++ G + L+ I K KG + F PE A +A
Sbjct: 403 RLFVRNLPYTSTEEDLEKLFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSE 462
Query: 712 MNGMKLSGREIDV 724
++G GR + V
Sbjct: 463 VDGQVFQGRMLHV 475
Score = 30.4 bits (67), Expect = 6.1
Identities = 19/63 (30%), Positives = 29/63 (46%), Gaps = 1/63 (1%)
Query: 72 RAFITNIPFDVKWQSLKDLVKEKVGEVTYVELLMDAEGKSRGCAVVEFKMEESMKKAAEV 131
R + N+P +K + + L G +T L +GK R + FK EE +KA +
Sbjct: 3 RLIVKNLPNGMKEERFRQLFAA-FGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQKH 61
Query: 132 LNK 134
NK
Sbjct: 62 FNK 64
>gi|226497574 RNA binding motif protein 19 [Homo sapiens]
Length = 960
Score = 54.7 bits (130), Expect = 3e-07
Identities = 28/83 (33%), Positives = 46/83 (55%), Gaps = 5/83 (6%)
Query: 653 CQIFVRNLPFDFTWKMLKDKFNECGHVLYADIKMENGK-----SKGCGVVKFESPEVAER 707
C +F++NL FD T + LK+ F++ G V I + K S G G V++ PE A++
Sbjct: 730 CTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVEYRKPEQAQK 789
Query: 708 ACRMMNGMKLSGREIDVRIDRNA 730
A + + G + G +++VRI A
Sbjct: 790 ALKQLQGHVVDGHKLEVRISERA 812
Score = 50.4 bits (119), Expect = 6e-06
Identities = 64/275 (23%), Positives = 111/275 (40%), Gaps = 40/275 (14%)
Query: 4 GVEAAAE-VAATEIKMEEESGAPGVPSGNGAPGPKGEGERPAQNEKRKEKNIKRGGNRFE 62
G EA E +AT + E +S G G A G K E A+ EK +
Sbjct: 239 GSEAEEEDSSATPVLQERDSKGAGQEQGMPA-GKKRPPEARAETEKPANQK--------- 288
Query: 63 PYANPTKRYRAFITNIPFDVKWQSLKDLVKEKVGEVTYVELLMDAEGKSRGCAVVEFKME 122
PT + + PF+V +++ + + + + ++ +A G G V+F E
Sbjct: 289 ---EPTTCHTVKLRGAPFNVTEKNVMEFLAPL--KPVAIRIVRNAHGNKTGYIFVDFSNE 343
Query: 123 ESMKKAAEVLNKHSLSGRPLKVKEDPDGEHARRAMQKVMATTGGMGMGPGGPGMITIPPS 182
E +K+A + N+ + GR ++V + + + A + + G +G
Sbjct: 344 EEVKQALKC-NREYMGGRYIEVFREKNVPTTKGAPKNTTKSWQGRILGEN---------- 392
Query: 183 ILNNPNIPNEIIHALQAGRLGSTVFVANLDYKVGWKKLKEVFSMAGVVVRADI-LEDKDG 241
E ++GRL FV NL Y + L+++FS G + ++
Sbjct: 393 --------EEEEDLAESGRL----FVRNLPYTSTEEDLEKLFSKYGPLSELHYPIDSLTK 440
Query: 242 KSRGIGTVTFEQSIEAVQAISMFNGQLLFDRPMHV 276
K +G +TF AV+A S +GQ+ R +HV
Sbjct: 441 KPKGFAFITFMFPEHAVKAYSEVDGQVFQGRMLHV 475
Score = 47.0 bits (110), Expect = 6e-05
Identities = 27/84 (32%), Positives = 44/84 (52%), Gaps = 4/84 (4%)
Query: 203 GSTVFVANLDYKVGWKKLKEVFSMAGVVVRADILEDKDGK----SRGIGTVTFEQSIEAV 258
G T+F+ NL++ +KLKEVFS G V I + K+ S G G V + + +A
Sbjct: 729 GCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVEYRKPEQAQ 788
Query: 259 QAISMFNGQLLFDRPMHVKMDERA 282
+A+ G ++ + V++ ERA
Sbjct: 789 KALKQLQGHVVDGHKLEVRISERA 812
Score = 36.6 bits (83), Expect = 0.085
Identities = 24/73 (32%), Positives = 38/73 (52%), Gaps = 2/73 (2%)
Query: 654 QIFVRNLPFDFTWKMLKDKFNECGHV--LYADIKMENGKSKGCGVVKFESPEVAERACRM 711
++FVRNLP+ T + L+ F++ G + L+ I K KG + F PE A +A
Sbjct: 403 RLFVRNLPYTSTEEDLEKLFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSE 462
Query: 712 MNGMKLSGREIDV 724
++G GR + V
Sbjct: 463 VDGQVFQGRMLHV 475
Score = 30.4 bits (67), Expect = 6.1
Identities = 19/63 (30%), Positives = 29/63 (46%), Gaps = 1/63 (1%)
Query: 72 RAFITNIPFDVKWQSLKDLVKEKVGEVTYVELLMDAEGKSRGCAVVEFKMEESMKKAAEV 131
R + N+P +K + + L G +T L +GK R + FK EE +KA +
Sbjct: 3 RLIVKNLPNGMKEERFRQLFAA-FGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQKH 61
Query: 132 LNK 134
NK
Sbjct: 62 FNK 64
>gi|14149675 cleavage stimulation factor, 3' pre-RNA, subunit 2,
64kDa, tau variant [Homo sapiens]
Length = 616
Score = 54.7 bits (130), Expect = 3e-07
Identities = 32/87 (36%), Positives = 48/87 (55%), Gaps = 4/87 (4%)
Query: 646 PGVARKACQIFVRNLPFDFTWKMLKDKFNECGHVLYADI--KMENGKSKGCGVVKFESPE 703
P + R +FV N+P++ T + LKD F+E G V+ + E GK KG G +++ E
Sbjct: 9 PAMDRSLRSVFVGNIPYEATEEQLKDIFSEVGSVVSFRLVYDRETGKPKGYGFCEYQDQE 68
Query: 704 VAERACRMMNGMKLSGREIDVRIDRNA 730
A A R +NG + SGR + R+D A
Sbjct: 69 TALSAMRNLNGREFSGRAL--RVDNAA 93
Score = 48.9 bits (115), Expect = 2e-05
Identities = 130/582 (22%), Positives = 202/582 (34%), Gaps = 87/582 (14%)
Query: 74 FITNIPFDVKWQSLKDLVKEKVGEVTYVELLMDAE-GKSRGCAVVEFKMEESMKKAAEVL 132
F+ NIP++ + LKD+ E VG V L+ D E GK +G E++ +E+ A L
Sbjct: 19 FVGNIPYEATEEQLKDIFSE-VGSVVSFRLVYDRETGKPKGYGFCEYQDQETALSAMRNL 77
Query: 133 NKHSLSGRPLKVKEDPDGEHARRAMQKVMATTGGMGMGPGGP------------GMITIP 180
N SGR L+V ++ E + ++ + + G P + ++P
Sbjct: 78 NGREFSGRALRV-DNAASEKNKEELKSLGPAAPIIDSPYGDPIDPEDAPESITRAVASLP 136
Query: 181 PS-----------------------ILNNPNIPNEIIHALQAGRLGSTVFVANLDYKVGW 217
P +L NP ++ +AL ++ + + K+
Sbjct: 137 PEQMFELMKQMKLCVQNSHQEARNMLLQNP----QLAYALLQAQVVMRIMDPEIALKILH 192
Query: 218 KKLKEVFSMAGVVVRADILEDKDGKSRGI----GTVTFEQSIEAVQAISMFNGQLLFDRP 273
+K+ + G + G G+ + +Q+ A Q Q L RP
Sbjct: 193 RKIHVTPLIPGKSQSVSVSGPGPGPGPGLCPGPNVLLNQQNPPAPQP------QHLARRP 246
Query: 274 MHVKMDERALPKGDFFPPERPQQLPHGLGGIGMG-LGPGGQPIDANHLNKGIGMGNIGPA 332
+ P P P +P + G G G L PGG + +GM +GP
Sbjct: 247 VKDIPPLMQTPIQGGIPAPGP--IPAAVPGAGPGSLTPGGA------MQPQLGMPGVGPV 298
Query: 333 GMGMEGIGFGINKMGGMEGPF-GGGMENMGRFGSGMNMGRINEILSNALKRGEIIAKQGG 391
+ + + GP GG+ G G N R +LS GE + +G
Sbjct: 299 PLERGQVQMSDPRAPIPRGPVTPGGLPPRGLLGDAPNDPRGGTLLS---VTGE-VEPRGY 354
Query: 392 GGGGGSVPGIERMGPGIDRLGGAGMERMGAGLGHGMDRVGSE----IERMGLVMDRMGSV 447
G P + G D G + E G LG +G I++ GL MD G
Sbjct: 355 LGPPHQGPPMHH-ASGHDTRGPSSHEMRGGPLGDPRLLIGEPRGPMIDQRGLPMDGRGGR 413
Query: 448 ERMGSGIERMGPLGLDHMASSIERMG-QTMERIGSGVERMGAGMGFGLE-RMAAPIDRVG 505
+ M L+ +ER G +T G+E G GLE R P R
Sbjct: 414 DSRAMETRAMETEVLE--TRVMERRGMETCAMETRGMEARGMD-ARGLEMRGPVPSSRGP 470
Query: 506 QTIERMGSGVERMGPAIERMGLSMERMVPAGMGAGLERMGPVMDRMATGLERMGANNLER 565
T G G +G G R VP G G P TG++ G
Sbjct: 471 MTGGIQGPGPINIGAGGPPQG---PRQVPGISGVG----NPGAGMQGTGIQGTGMQGAGI 523
Query: 566 MGLERMGAN----SLERMGLERMGANSLERMGPAMGPALGAG 603
G GA S++ G++ G + G + + G
Sbjct: 524 QGGGMQGAGIQGVSIQGGGIQGGGIQGASKQGGSQPSSFSPG 565
Score = 42.7 bits (99), Expect = 0.001
Identities = 23/73 (31%), Positives = 41/73 (56%), Gaps = 1/73 (1%)
Query: 205 TVFVANLDYKVGWKKLKEVFSMAGVVVRADILEDKD-GKSRGIGTVTFEQSIEAVQAISM 263
+VFV N+ Y+ ++LK++FS G VV ++ D++ GK +G G ++ A+ A+
Sbjct: 17 SVFVGNIPYEATEEQLKDIFSEVGSVVSFRLVYDRETGKPKGYGFCEYQDQETALSAMRN 76
Query: 264 FNGQLLFDRPMHV 276
NG+ R + V
Sbjct: 77 LNGREFSGRALRV 89
Score = 40.4 bits (93), Expect = 0.006
Identities = 34/117 (29%), Positives = 50/117 (42%), Gaps = 33/117 (28%)
Query: 290 PPERPQQLPHGLGGIGMGLGPGGQPIDANHLNKGIGMGNIGPAGMGMEGIGFGINKMGGM 349
PP+ P+Q+P G+ G+G N G GM G G GM+G G + GGM
Sbjct: 488 PPQGPRQVP-GISGVG---------------NPGAGMQGTGIQGTGMQGAGI---QGGGM 528
Query: 350 EGPFGGGMENMGRFGSGMNMGRINEILSNALKRGEIIAKQGGGGGGGSVPGIERMGP 406
+ G G++ + G G+ G I + +KQGG PG ++ P
Sbjct: 529 Q---GAGIQGVSIQGGGIQGGGI-----------QGASKQGGSQPSSFSPGQSQVTP 571
Score = 32.0 bits (71), Expect = 2.1
Identities = 68/276 (24%), Positives = 94/276 (34%), Gaps = 31/276 (11%)
Query: 383 GEIIAKQGGGGGGGSVPG--------IERMGPGIDRLGGAGMERMGAGLGHGMDRVGSEI 434
G I A G G G PG + +GP G M A + G G
Sbjct: 266 GPIPAAVPGAGPGSLTPGGAMQPQLGMPGVGPVPLERGQVQMSDPRAPIPRGPVTPGGLP 325
Query: 435 ERMGLVMD-----RMGSVERMGSGIERMGPLGLDHMASSIERMGQTMERIGSGVERMGAG 489
R GL+ D R G++ + +E G LG H + R S E G
Sbjct: 326 PR-GLLGDAPNDPRGGTLLSVTGEVEPRGYLGPPHQGPPMHHASGHDTRGPSSHEMRGGP 384
Query: 490 MGFGLERMAAP----IDRVGQTIERMGSGVERMGPAIERMGLSMERMVPAGMGAGLERMG 545
+G + P ID+ G ++ G R A+E + E + M ER G
Sbjct: 385 LGDPRLLIGEPRGPMIDQRGLPMDGRGGRDSR---AMETRAMETEVLETRVM----ERRG 437
Query: 546 PVMDRMATGLERMGANNLERMGLERMGANSLERM----GLERMGANSLERMGPAMGPALG 601
M+ A M A ++ GLE G R G++ G ++ GP GP
Sbjct: 438 --METCAMETRGMEARGMDARGLEMRGPVPSSRGPMTGGIQGPGPINIGAGGPPQGPRQV 495
Query: 602 AGIERMGLAMGGGGGASFDRAIEMERGNFGGSFAGS 637
GI +G G G G GG G+
Sbjct: 496 PGISGVGNPGAGMQGTGIQGTGMQGAGIQGGGMQGA 531
>gi|238776833 THO complex 4 [Homo sapiens]
Length = 264
Score = 54.3 bits (129), Expect = 4e-07
Identities = 34/110 (30%), Positives = 57/110 (51%), Gaps = 6/110 (5%)
Query: 203 GSTVFVANLDYKVGWKKLKEVFSMAGVVVRADILEDKDGKSRGIGTVTFEQSIEAVQAIS 262
G + V+NLD+ V ++E+F+ G + +A + D+ G+S G V FE+ +A++A+
Sbjct: 112 GGKLLVSNLDFGVSDADIQELFAEFGTLKKAAVHYDRSGRSLGTADVHFERKADALKAMK 171
Query: 263 MFNGQLLFDRPMHVKMDERALPKGDFFPPERPQQLPHGLGGIGMGLGPGG 312
+NG L RPM+++ L RP Q + GG+ G GG
Sbjct: 172 QYNGVPLDGRPMNIQ-----LVTSQIDAQRRPAQSVN-RGGMTRNRGAGG 215
Score = 43.9 bits (102), Expect = 5e-04
Identities = 39/145 (26%), Positives = 63/145 (43%), Gaps = 8/145 (5%)
Query: 585 GANSLERMGPAMGPALGAGIERMGLAMGGGGG--ASFDRAIEMERGNFGGSFAGSFGGAG 642
GA + R+ GP G A GGG A + R ++ F FGG
Sbjct: 48 GAQAAARVNRGGGPIRNRPAIARGAAGGGGRNRPAPYSRPKQLPDKWQHDLFDSGFGGGA 107
Query: 643 GHAPGVARKACQIFVRNLPFDFTWKMLKDKFNECGHVLYADIKME-NGKSKGCGVVKFES 701
G G ++ V NL F + +++ F E G + A + + +G+S G V FE
Sbjct: 108 GVETGG-----KLLVSNLDFGVSDADIQELFAEFGTLKKAAVHYDRSGRSLGTADVHFER 162
Query: 702 PEVAERACRMMNGMKLSGREIDVRI 726
A +A + NG+ L GR +++++
Sbjct: 163 KADALKAMKQYNGVPLDGRPMNIQL 187
Score = 37.0 bits (84), Expect = 0.065
Identities = 42/173 (24%), Positives = 66/173 (38%), Gaps = 6/173 (3%)
Query: 4 GVEAAAEVAATEIKMEEESGAPGVPSGNGAPGPKGEGERPAQNEKRKEKNIKRGGNRFEP 63
G +AAA V + +G G RP Q + + ++ G F
Sbjct: 48 GAQAAARVNRGGGPIRNRPAIARGAAGGGGRNRPAPYSRPKQLPDKWQHDLFDSG--FGG 105
Query: 64 YANPTKRYRAFITNIPFDVKWQSLKDLVKEKVGEVTYVELLMDAEGKSRGCAVVEFKMEE 123
A + ++N+ F V +++L E G + + D G+S G A V F+ +
Sbjct: 106 GAGVETGGKLLVSNLDFGVSDADIQELFAE-FGTLKKAAVHYDRSGRSLGTADVHFERKA 164
Query: 124 SMKKAAEVLNKHSLSGRPLKVK-EDPDGEHARRAMQKVMATTGGMGMGPGGPG 175
KA + N L GRP+ ++ + RR Q V GGM G G
Sbjct: 165 DALKAMKQYNGVPLDGRPMNIQLVTSQIDAQRRPAQSV--NRGGMTRNRGAGG 215
>gi|253970504 Ewing sarcoma breakpoint region 1 isoform 4 [Homo
sapiens]
Length = 600
Score = 53.1 bits (126), Expect = 9e-07
Identities = 87/317 (27%), Positives = 115/317 (36%), Gaps = 58/317 (18%)
Query: 165 GGMGMG--------PGGPGMITIPPSILNNPNIPNEIIHALQAGRLGSTVFVANLDYKVG 216
GGMG PGGP M P L P P+E S ++V L+ V
Sbjct: 266 GGMGSAGERGGFNKPGGP-MDEGPDLDLGPPVDPDEDSD-------NSAIYVQGLNDSVT 317
Query: 217 WKKLKEVFSMAGVVVRAD---------ILEDKDGKSRGIGTVTFEQSIEAVQAISMFNGQ 267
L + F GVV L+ + GK +G TV++E A A+ F+G+
Sbjct: 318 LDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGK 377
Query: 268 LLFDRPMHVKMDERALPKGDF---FPPERPQQLPHGL-GGIGMGLGPGGQPIDANHLNKG 323
+ V + + P PP + +P L GG G GPGG
Sbjct: 378 DFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGP---------- 427
Query: 324 IGMGNIGPAGMGMEGIGFGINKMGGMEGPFGGGMENMGRFGSGM--NMGRINEILSNALK 381
MG +G G G + GF G G GG R G N G N+ + +
Sbjct: 428 --MGRMG--GRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTE 483
Query: 382 RGEIIAKQG-----------GGGGGGSVPGIERMGPG--IDRLGGAGMERMGAGLGHGMD 428
+ A + GG G PG R G G +DR G GM R G G G
Sbjct: 484 CNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGF 543
Query: 429 RVGSEIERMGLVMDRMG 445
R G ++R G R G
Sbjct: 544 RGGRGMDRGGFGGGRRG 560
Score = 45.1 bits (105), Expect = 2e-04
Identities = 46/178 (25%), Positives = 62/178 (34%), Gaps = 26/178 (14%)
Query: 571 MGANSLERMGLERMGANSLERMGPAMGPALGAGIERMGLAMGGGGGASFDRAIEMERGNF 630
MG E G G N GP G +R G++ GG GG ERG F
Sbjct: 219 MGVYGQESGGFSGPGENR-SMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGF 277
Query: 631 GGSFAGSFGGAGGHAPGVA----------RKACQIFVRNLPFDFTWKMLKDKFNECGHV- 679
GG P + I+V+ L T L D F +CG V
Sbjct: 278 NKP-----GGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVK 332
Query: 680 ---------LYADIKMENGKSKGCGVVKFESPEVAERACRMMNGMKLSGREIDVRIDR 728
++ + E GK KG V +E P A+ A +G G ++ V + R
Sbjct: 333 MNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLAR 390
Score = 34.3 bits (77), Expect = 0.42
Identities = 30/83 (36%), Positives = 37/83 (44%), Gaps = 5/83 (6%)
Query: 284 PKGDFFPPERPQQLPHGLGGIGMGLGPGGQPIDANH---LNKGIGMGNIGP--AGMGMEG 338
P+G PP P G GG G G G +D + +G G+ G G GM+
Sbjct: 492 PEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDR 551
Query: 339 IGFGINKMGGMEGPFGGGMENMG 361
GFG + GG GP G ME MG
Sbjct: 552 GGFGGGRRGGPGGPPGPLMEQMG 574
>gi|4885225 Ewing sarcoma breakpoint region 1 isoform 2 [Homo
sapiens]
Length = 656
Score = 53.1 bits (126), Expect = 9e-07
Identities = 87/317 (27%), Positives = 115/317 (36%), Gaps = 58/317 (18%)
Query: 165 GGMGMG--------PGGPGMITIPPSILNNPNIPNEIIHALQAGRLGSTVFVANLDYKVG 216
GGMG PGGP M P L P P+E S ++V L+ V
Sbjct: 322 GGMGSAGERGGFNKPGGP-MDEGPDLDLGPPVDPDEDSD-------NSAIYVQGLNDSVT 373
Query: 217 WKKLKEVFSMAGVVVRAD---------ILEDKDGKSRGIGTVTFEQSIEAVQAISMFNGQ 267
L + F GVV L+ + GK +G TV++E A A+ F+G+
Sbjct: 374 LDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGK 433
Query: 268 LLFDRPMHVKMDERALPKGDF---FPPERPQQLPHGL-GGIGMGLGPGGQPIDANHLNKG 323
+ V + + P PP + +P L GG G GPGG
Sbjct: 434 DFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGP---------- 483
Query: 324 IGMGNIGPAGMGMEGIGFGINKMGGMEGPFGGGMENMGRFGSGM--NMGRINEILSNALK 381
MG +G G G + GF G G GG R G N G N+ + +
Sbjct: 484 --MGRMG--GRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTE 539
Query: 382 RGEIIAKQG-----------GGGGGGSVPGIERMGPG--IDRLGGAGMERMGAGLGHGMD 428
+ A + GG G PG R G G +DR G GM R G G G
Sbjct: 540 CNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGF 599
Query: 429 RVGSEIERMGLVMDRMG 445
R G ++R G R G
Sbjct: 600 RGGRGMDRGGFGGGRRG 616
Score = 45.1 bits (105), Expect = 2e-04
Identities = 46/178 (25%), Positives = 62/178 (34%), Gaps = 26/178 (14%)
Query: 571 MGANSLERMGLERMGANSLERMGPAMGPALGAGIERMGLAMGGGGGASFDRAIEMERGNF 630
MG E G G N GP G +R G++ GG GG ERG F
Sbjct: 275 MGVYGQESGGFSGPGENR-SMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGF 333
Query: 631 GGSFAGSFGGAGGHAPGVA----------RKACQIFVRNLPFDFTWKMLKDKFNECGHV- 679
GG P + I+V+ L T L D F +CG V
Sbjct: 334 NKP-----GGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVK 388
Query: 680 ---------LYADIKMENGKSKGCGVVKFESPEVAERACRMMNGMKLSGREIDVRIDR 728
++ + E GK KG V +E P A+ A +G G ++ V + R
Sbjct: 389 MNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLAR 446
Score = 34.3 bits (77), Expect = 0.42
Identities = 30/83 (36%), Positives = 37/83 (44%), Gaps = 5/83 (6%)
Query: 284 PKGDFFPPERPQQLPHGLGGIGMGLGPGGQPIDANH---LNKGIGMGNIGP--AGMGMEG 338
P+G PP P G GG G G G +D + +G G+ G G GM+
Sbjct: 548 PEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDR 607
Query: 339 IGFGINKMGGMEGPFGGGMENMG 361
GFG + GG GP G ME MG
Sbjct: 608 GGFGGGRRGGPGGPPGPLMEQMG 630
>gi|169234630 RNA binding motif protein 11 [Homo sapiens]
Length = 281
Score = 53.1 bits (126), Expect = 9e-07
Identities = 27/73 (36%), Positives = 44/73 (60%)
Query: 205 TVFVANLDYKVGWKKLKEVFSMAGVVVRADILEDKDGKSRGIGTVTFEQSIEAVQAISMF 264
TVFV NL+ +V + L E+F AG + + I +D++GK + G V F+ AI++
Sbjct: 11 TVFVGNLEARVREEILYELFLQAGPLTKVTICKDREGKPKSFGFVCFKHPESVSYAIALL 70
Query: 265 NGQLLFDRPMHVK 277
NG L+ RP++V+
Sbjct: 71 NGIRLYGRPINVQ 83
Score = 39.7 bits (91), Expect = 0.010
Identities = 25/72 (34%), Positives = 38/72 (52%), Gaps = 1/72 (1%)
Query: 655 IFVRNLPFDFTWKMLKDKFNECGHVLYADI-KMENGKSKGCGVVKFESPEVAERACRMMN 713
+FV NL ++L + F + G + I K GK K G V F+ PE A ++N
Sbjct: 12 VFVGNLEARVREEILYELFLQAGPLTKVTICKDREGKPKSFGFVCFKHPESVSYAIALLN 71
Query: 714 GMKLSGREIDVR 725
G++L GR I+V+
Sbjct: 72 GIRLYGRPINVQ 83
Score = 38.9 bits (89), Expect = 0.017
Identities = 25/72 (34%), Positives = 38/72 (52%), Gaps = 1/72 (1%)
Query: 74 FITNIPFDVKWQSLKDLVKEKVGEVTYVELLMDAEGKSRGCAVVEFKMEESMKKAAEVLN 133
F+ N+ V+ + L +L + G +T V + D EGK + V FK ES+ A +LN
Sbjct: 13 FVGNLEARVREEILYELFLQ-AGPLTKVTICKDREGKPKSFGFVCFKHPESVSYAIALLN 71
Query: 134 KHSLSGRPLKVK 145
L GRP+ V+
Sbjct: 72 GIRLYGRPINVQ 83
>gi|56699409 RNA binding motif protein, X-linked [Homo sapiens]
Length = 391
Score = 52.0 bits (123), Expect = 2e-06
Identities = 41/134 (30%), Positives = 65/134 (48%), Gaps = 10/134 (7%)
Query: 197 LQAGRLGSTVFVANLDYKVGWKKLKEVFSMAGVVVRADILEDKD-GKSRGIGTVTFEQSI 255
++A R G +F+ L+ + K L+ VF G +V +++D++ KSRG VTFE
Sbjct: 2 VEADRPGK-LFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPA 60
Query: 256 EAVQAISMFNGQLLFDRPMHVKMDERALPKGDFF-----PPERPQQLPHGL-GGIGMGLG 309
+A A NG+ L + +K+++ P + PP R + P GL GG G G
Sbjct: 61 DAKDAARDMNGKSLDGKA--IKVEQATKPSFESGRRGPPPPPRSRGPPRGLRGGRGGSGG 118
Query: 310 PGGQPIDANHLNKG 323
G P H++ G
Sbjct: 119 TRGPPSRGGHMDDG 132
Score = 45.1 bits (105), Expect = 2e-04
Identities = 35/95 (36%), Positives = 45/95 (47%), Gaps = 6/95 (6%)
Query: 94 KVGEVTYVELLMDAE-GKSRGCAVVEFKMEESMKKAAEVLNKHSLSGRPLKVKE--DPDG 150
K G + V L+ D E KSRG A V F+ K AA +N SL G+ +KV++ P
Sbjct: 30 KYGRIVEVLLMKDRETNKSRGFAFVTFESPADAKDAARDMNGKSLDGKAIKVEQATKPSF 89
Query: 151 EHARRAMQKVMATTG---GMGMGPGGPGMITIPPS 182
E RR + G G+ G GG G PPS
Sbjct: 90 ESGRRGPPPPPRSRGPPRGLRGGRGGSGGTRGPPS 124
Score = 39.7 bits (91), Expect = 0.010
Identities = 25/73 (34%), Positives = 37/73 (50%), Gaps = 2/73 (2%)
Query: 654 QIFVRNLPFDFTWKMLKDKFNECGHVLYADIKM--ENGKSKGCGVVKFESPEVAERACRM 711
++F+ L + K L+ F + G ++ + E KS+G V FESP A+ A R
Sbjct: 9 KLFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPADAKDAARD 68
Query: 712 MNGMKLSGREIDV 724
MNG L G+ I V
Sbjct: 69 MNGKSLDGKAIKV 81
>gi|242117971 RNA binding motif protein, X-linked-like 1 [Homo
sapiens]
Length = 390
Score = 51.6 bits (122), Expect = 3e-06
Identities = 40/132 (30%), Positives = 64/132 (48%), Gaps = 6/132 (4%)
Query: 197 LQAGRLGSTVFVANLDYKVGWKKLKEVFSMAGVVVRADILEDKD-GKSRGIGTVTFEQSI 255
++A R G +F+ L+ + K L+ VF G +V +++D++ KSRG VTFE
Sbjct: 2 VEADRPGK-LFIGGLNTETNEKALETVFGKYGRIVEVLLIKDRETNKSRGFAFVTFESPA 60
Query: 256 EAVQAISMFNGQLLFDRPMHVKMDER-ALPKGDFFPPERPQQL--PHGLG-GIGMGLGPG 311
+A A NG+ L + + V+ + + +G PP P+ P G G G G G
Sbjct: 61 DAKDAARDMNGKSLDGKAIKVEQATKPSFERGRHGPPPPPRSRGPPRGFGAGRGGSGGTR 120
Query: 312 GQPIDANHLNKG 323
G P H++ G
Sbjct: 121 GPPSRGGHMDDG 132
Score = 46.6 bits (109), Expect = 8e-05
Identities = 35/95 (36%), Positives = 44/95 (46%), Gaps = 6/95 (6%)
Query: 94 KVGEVTYVELLMDAE-GKSRGCAVVEFKMEESMKKAAEVLNKHSLSGRPLKVKE--DPDG 150
K G + V L+ D E KSRG A V F+ K AA +N SL G+ +KV++ P
Sbjct: 30 KYGRIVEVLLIKDRETNKSRGFAFVTFESPADAKDAARDMNGKSLDGKAIKVEQATKPSF 89
Query: 151 EHARRAMQKVMATTG---GMGMGPGGPGMITIPPS 182
E R + G G G G GG G PPS
Sbjct: 90 ERGRHGPPPPPRSRGPPRGFGAGRGGSGGTRGPPS 124
Score = 40.0 bits (92), Expect = 0.008
Identities = 25/73 (34%), Positives = 37/73 (50%), Gaps = 2/73 (2%)
Query: 654 QIFVRNLPFDFTWKMLKDKFNECGHVLYADI--KMENGKSKGCGVVKFESPEVAERACRM 711
++F+ L + K L+ F + G ++ + E KS+G V FESP A+ A R
Sbjct: 9 KLFIGGLNTETNEKALETVFGKYGRIVEVLLIKDRETNKSRGFAFVTFESPADAKDAARD 68
Query: 712 MNGMKLSGREIDV 724
MNG L G+ I V
Sbjct: 69 MNGKSLDGKAIKV 81
>gi|21361809 RNA binding motif protein, X-linked-like 1 [Homo
sapiens]
Length = 390
Score = 51.6 bits (122), Expect = 3e-06
Identities = 40/132 (30%), Positives = 64/132 (48%), Gaps = 6/132 (4%)
Query: 197 LQAGRLGSTVFVANLDYKVGWKKLKEVFSMAGVVVRADILEDKD-GKSRGIGTVTFEQSI 255
++A R G +F+ L+ + K L+ VF G +V +++D++ KSRG VTFE
Sbjct: 2 VEADRPGK-LFIGGLNTETNEKALETVFGKYGRIVEVLLIKDRETNKSRGFAFVTFESPA 60
Query: 256 EAVQAISMFNGQLLFDRPMHVKMDER-ALPKGDFFPPERPQQL--PHGLG-GIGMGLGPG 311
+A A NG+ L + + V+ + + +G PP P+ P G G G G G
Sbjct: 61 DAKDAARDMNGKSLDGKAIKVEQATKPSFERGRHGPPPPPRSRGPPRGFGAGRGGSGGTR 120
Query: 312 GQPIDANHLNKG 323
G P H++ G
Sbjct: 121 GPPSRGGHMDDG 132
Score = 46.6 bits (109), Expect = 8e-05
Identities = 35/95 (36%), Positives = 44/95 (46%), Gaps = 6/95 (6%)
Query: 94 KVGEVTYVELLMDAE-GKSRGCAVVEFKMEESMKKAAEVLNKHSLSGRPLKVKE--DPDG 150
K G + V L+ D E KSRG A V F+ K AA +N SL G+ +KV++ P
Sbjct: 30 KYGRIVEVLLIKDRETNKSRGFAFVTFESPADAKDAARDMNGKSLDGKAIKVEQATKPSF 89
Query: 151 EHARRAMQKVMATTG---GMGMGPGGPGMITIPPS 182
E R + G G G G GG G PPS
Sbjct: 90 ERGRHGPPPPPRSRGPPRGFGAGRGGSGGTRGPPS 124
Score = 40.0 bits (92), Expect = 0.008
Identities = 25/73 (34%), Positives = 37/73 (50%), Gaps = 2/73 (2%)
Query: 654 QIFVRNLPFDFTWKMLKDKFNECGHVLYADI--KMENGKSKGCGVVKFESPEVAERACRM 711
++F+ L + K L+ F + G ++ + E KS+G V FESP A+ A R
Sbjct: 9 KLFIGGLNTETNEKALETVFGKYGRIVEVLLIKDRETNKSRGFAFVTFESPADAKDAARD 68
Query: 712 MNGMKLSGREIDV 724
MNG L G+ I V
Sbjct: 69 MNGKSLDGKAIKV 81
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.138 0.406
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,455,208
Number of Sequences: 37866
Number of extensions: 1712807
Number of successful extensions: 15385
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 165
Number of HSP's successfully gapped in prelim test: 248
Number of HSP's that attempted gapping in prelim test: 10838
Number of HSP's gapped (non-prelim): 3841
length of query: 730
length of database: 18,247,518
effective HSP length: 110
effective length of query: 620
effective length of database: 14,082,258
effective search space: 8730999960
effective search space used: 8730999960
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.