Guide to the Human Genome
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Search of human proteins with 7661968

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7661968 epsin 4 [Homo sapiens]
         (625 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7661968 epsin 4 [Homo sapiens]                                    1252   0.0  
gi|156671217 epsin 2 isoform a [Homo sapiens]                         176   8e-44
gi|194248095 epsin 1 isoform b [Homo sapiens]                         174   2e-43
gi|157388929 epsin 3 [Homo sapiens]                                   172   1e-42
gi|41350201 epsin 1 isoform c [Homo sapiens]                          169   5e-42
gi|194272148 epsin 1 isoform a [Homo sapiens]                         169   5e-42
gi|156671215 epsin 2 isoform b [Homo sapiens]                         169   5e-42
gi|31377575 ENTH domain containing 1 [Homo sapiens]                   139   6e-33
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    54   3e-07
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        51   4e-06
gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 ...    49   1e-05
gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 ...    49   1e-05
gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 ...    49   1e-05
gi|28559039 mediator complex subunit 1 [Homo sapiens]                  46   1e-04
gi|151301154 mucin 6, gastric [Homo sapiens]                           46   1e-04
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                        45   3e-04
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]         44   3e-04
gi|239754668 PREDICTED: mucin 12 [Homo sapiens]                        42   0.001
gi|167736355 mucin 4 isoform a [Homo sapiens]                          42   0.001
gi|24308215 retrotransposon gag domain containing 1 [Homo sapiens]     42   0.001
gi|5174545 myocyte enhancer factor 2D [Homo sapiens]                   42   0.002
gi|33946327 nucleoporin 214kDa [Homo sapiens]                          42   0.002
gi|221219020 NYD-SP11 protein [Homo sapiens]                           41   0.003
gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ...    41   0.003
gi|91984781 ArfGAP with FG repeats 2 [Homo sapiens]                    41   0.004
gi|7657387 CCR4-NOT transcription complex, subunit 3 [Homo sapiens]    41   0.004
gi|7661950 SH2 domain binding protein 1 [Homo sapiens]                 40   0.005
gi|16753205 ubiquilin 1 isoform 2 [Homo sapiens]                       40   0.006
gi|239749217 PREDICTED: similar to Mucin-12, partial [Homo sapiens]    40   0.008
gi|67782356 corneodesmosin precursor [Homo sapiens]                    40   0.008

>gi|7661968 epsin 4 [Homo sapiens]
          Length = 625

 Score = 1252 bits (3240), Expect = 0.0
 Identities = 625/625 (100%), Positives = 625/625 (100%)

Query: 1   MLNMWKVRELVDKATNVVMNYSEIESKVREATNDDPWGPSGQLMGEIAKATFMYEQFPEL 60
           MLNMWKVRELVDKATNVVMNYSEIESKVREATNDDPWGPSGQLMGEIAKATFMYEQFPEL
Sbjct: 1   MLNMWKVRELVDKATNVVMNYSEIESKVREATNDDPWGPSGQLMGEIAKATFMYEQFPEL 60

Query: 61  MNMLWSRMLKDNKKNWRRVYKSLLLLAYLIRNGSERVVTSAREHIYDLRSLENYHFVDEH 120
           MNMLWSRMLKDNKKNWRRVYKSLLLLAYLIRNGSERVVTSAREHIYDLRSLENYHFVDEH
Sbjct: 61  MNMLWSRMLKDNKKNWRRVYKSLLLLAYLIRNGSERVVTSAREHIYDLRSLENYHFVDEH 120

Query: 121 GKDQGINIRQKVKELVEFAQDDDRLREERKKAKKNKDKYVGVSSDSVGGFRYSERYDPEP 180
           GKDQGINIRQKVKELVEFAQDDDRLREERKKAKKNKDKYVGVSSDSVGGFRYSERYDPEP
Sbjct: 121 GKDQGINIRQKVKELVEFAQDDDRLREERKKAKKNKDKYVGVSSDSVGGFRYSERYDPEP 180

Query: 181 KSKWDEEWDKNKSAFPFSDKLGELSDKIGSTIDDTISKFRRKDREDSPERCSDSDEEKKA 240
           KSKWDEEWDKNKSAFPFSDKLGELSDKIGSTIDDTISKFRRKDREDSPERCSDSDEEKKA
Sbjct: 181 KSKWDEEWDKNKSAFPFSDKLGELSDKIGSTIDDTISKFRRKDREDSPERCSDSDEEKKA 240

Query: 241 RRGRSPKGEFKDEEETVTTKHIHITQATETTTTRHKRTANPSKTIDLGAAAHYTGDKASP 300
           RRGRSPKGEFKDEEETVTTKHIHITQATETTTTRHKRTANPSKTIDLGAAAHYTGDKASP
Sbjct: 241 RRGRSPKGEFKDEEETVTTKHIHITQATETTTTRHKRTANPSKTIDLGAAAHYTGDKASP 300

Query: 301 DQNASTHTPQSSVKTSVPSSKSSGDLVDLFDGTSQSTGGSADLFGGFADFGSAAASGSFP 360
           DQNASTHTPQSSVKTSVPSSKSSGDLVDLFDGTSQSTGGSADLFGGFADFGSAAASGSFP
Sbjct: 301 DQNASTHTPQSSVKTSVPSSKSSGDLVDLFDGTSQSTGGSADLFGGFADFGSAAASGSFP 360

Query: 361 SQVTATSGNGDFGDWSAFNQAPSGPVASSGEFFGSASQPAVELVSGSQSALGPPPAASNS 420
           SQVTATSGNGDFGDWSAFNQAPSGPVASSGEFFGSASQPAVELVSGSQSALGPPPAASNS
Sbjct: 361 SQVTATSGNGDFGDWSAFNQAPSGPVASSGEFFGSASQPAVELVSGSQSALGPPPAASNS 420

Query: 421 SDLFDLMGSSQATMTSSQSMNFSMMSTNTVGLGLPMSRSQNTDMVQKSVSKTLPSTWSDP 480
           SDLFDLMGSSQATMTSSQSMNFSMMSTNTVGLGLPMSRSQNTDMVQKSVSKTLPSTWSDP
Sbjct: 421 SDLFDLMGSSQATMTSSQSMNFSMMSTNTVGLGLPMSRSQNTDMVQKSVSKTLPSTWSDP 480

Query: 481 SVNISLDNLLPGMQPSKPQQPSLNTMIQQQNMQQPMNVMTQSFGAVNLSSPSNMLPVRPQ 540
           SVNISLDNLLPGMQPSKPQQPSLNTMIQQQNMQQPMNVMTQSFGAVNLSSPSNMLPVRPQ
Sbjct: 481 SVNISLDNLLPGMQPSKPQQPSLNTMIQQQNMQQPMNVMTQSFGAVNLSSPSNMLPVRPQ 540

Query: 541 TNALIGGPMPMSMPNVMTGTMGMAPLGNTPMMNQSMMGMNMNIGMSAAGMGLTGTMGMGM 600
           TNALIGGPMPMSMPNVMTGTMGMAPLGNTPMMNQSMMGMNMNIGMSAAGMGLTGTMGMGM
Sbjct: 541 TNALIGGPMPMSMPNVMTGTMGMAPLGNTPMMNQSMMGMNMNIGMSAAGMGLTGTMGMGM 600

Query: 601 PNIAMTSGTVQPKQDAFANFANFSK 625
           PNIAMTSGTVQPKQDAFANFANFSK
Sbjct: 601 PNIAMTSGTVQPKQDAFANFANFSK 625


>gi|156671217 epsin 2 isoform a [Homo sapiens]
          Length = 584

 Score =  176 bits (445), Expect = 8e-44
 Identities = 169/604 (27%), Positives = 268/604 (44%), Gaps = 61/604 (10%)

Query: 16  NVVMNYSEIESKVREATNDDPWGPSGQLMGEIAKATFMYEQFPELMNMLWSRMLKDNKKN 75
           N+V NYSE E KVREAT++DPWGPS  LM EIA  T+    F E+M+M+W R L D+ KN
Sbjct: 12  NIVNNYSEAEIKVREATSNDPWGPSSSLMTEIADLTYNVVAFSEIMSMVWKR-LNDHGKN 70

Query: 76  WRRVYKSLLLLAYLIRNGSERVVTSAREHIYDLRSLENYHFVDEHGKDQGINIRQKVKEL 135
           WR VYK+L LL YLI+ GSERV    RE+I+ +++L+++ ++D  GKDQGIN+R+K K+L
Sbjct: 71  WRHVYKALTLLDYLIKTGSERVAQQCRENIFAIQTLKDFQYIDRDGKDQGINVREKSKQL 130

Query: 136 VEFAQDDDRLREERKKAKKNKDKYVGVSSDSVGGFRYSERYDPEPK-SKWDEEWDKNKSA 194
           V   +D++RL+ ER +A K K++   V++          R   +P  S    E +  K+ 
Sbjct: 131 VALLKDEERLKAERAQALKTKERMAQVATGMGSNQITFGRGSSQPNLSTSHSEQEYGKAG 190

Query: 195 FPFSDKLGELSDKIGSTIDDTISKFRRKDREDSPERCSDS----DEEKKARRGRSPKGEF 250
              +   G  S ++ S ++    +   ++        + S    ++E++ RRG   + + 
Sbjct: 191 GSPASYHGSTSPRVSSELEQARPQTSGEEELQLQLALAMSREVAEQEERLRRGDDLRLQM 250

Query: 251 KDEEETVTTKHIHITQATETTTTRHKRTANPSKTIDLGAAAHYTGDKASPDQNASTHTPQ 310
             EE    T  + I +  E     H      +  +DL  A   +G  A   Q A    P 
Sbjct: 251 ALEESRRDT--VKIPKKKE-----HGSLPQQTTLLDLMDALPSSGPAA---QKAEPWGPS 300

Query: 311 SSVKTSVPSSKSSGDLVDLFDGTSQSTGGSADLFGGFADFGSAAAS-GSFPSQVTATSGN 369
           +S   + P             G   +   ++D +  F    +A+      P+  T  S  
Sbjct: 301 ASTNQTNPW------------GGPAAPASTSDPWPSFGTKPAASIDPWGVPTGATVQSVP 348

Query: 370 GDFGDWSAFNQAPSGPVASSGEFFGSASQPAVELVSGSQSALGP-PPAASNSSDLFDLMG 428
            +   W+A  Q  S     + + +G+ S      VSGS            +    FD + 
Sbjct: 349 KNSDPWAASQQPASSAGKRASDAWGAVSTTKPVSVSGSFELFSNLNGTIKDDFSEFDNLR 408

Query: 429 SSQATMTSSQSMNFSMMSTNTVGLGLPMSRSQNTDMVQK--SVSKTLPSTWSDPSVNISL 486
           +S+ T  S  S+      T +     P      T    K  S  KT  S     +  ++L
Sbjct: 409 TSKKTAESVTSLPSQNNGTTSPD---PFESQPLTVASSKPSSARKTPESFLGPNAALVNL 465

Query: 487 DNLLPGMQPSKPQQPSLNTMIQ-------------QQNMQQPMNVMTQSFGAVNLSSPSN 533
           D+L+   +P+ P Q SLN  +              Q N  QP+  + Q  G+  L + ++
Sbjct: 466 DSLV--TRPAPPAQ-SLNPFLAPGAPATSAPVNPFQVNQPQPL-TLNQLRGSPVLGTSTS 521

Query: 534 MLPVRPQTNALIGGPMPMSMPNVMTGTMG--MAPLGNTPMMNQSMMGMNMNIGMSAAGMG 591
             P  P   ++    M  + P    G  G  + PLG       +MM M  ++G+  +   
Sbjct: 522 FGP-GPGVESMAVASMTSAAPQPALGATGSSLTPLG------PAMMNMVGSVGIPPSAAQ 574

Query: 592 LTGT 595
            TGT
Sbjct: 575 ATGT 578


>gi|194248095 epsin 1 isoform b [Homo sapiens]
          Length = 576

 Score =  174 bits (442), Expect = 2e-43
 Identities = 173/574 (30%), Positives = 254/574 (44%), Gaps = 57/574 (9%)

Query: 16  NVVMNYSEIESKVREATNDDPWGPSGQLMGEIAKATFMYEQFPELMNMLWSRMLKDNKKN 75
           N+V NYSE E KVREAT++DPWGPS  LM EIA  T+    F E+M+M+W R L D+ KN
Sbjct: 12  NIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMIWKR-LNDHGKN 70

Query: 76  WRRVYKSLLLLAYLIRNGSERVVTSAREHIYDLRSLENYHFVDEHGKDQGINIRQKVKEL 135
           WR VYK++ L+ YLI+ GSERV    +E++Y +++L+++ +VD  GKDQG+N+R+K K+L
Sbjct: 71  WRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQGVNVREKAKQL 130

Query: 136 VEFAQDDDRLREERKKAKKNKDKY---VGVSSDSVGGFRYSERYDPEPKSKWDEEWDKNK 192
           V   +D+DRLREER  A K K+K       SS +VG     E     P+S  +EE  + +
Sbjct: 131 VALLRDEDRLREERAHALKTKEKLAQTATASSAAVGSGPPPEAEQAWPQSSGEEEL-QLQ 189

Query: 193 SAFPFSDKLGELSDKIGSTIDDTISKFRRKDREDSPERCSDSDEEKKARRGRSPKGEFKD 252
            A   S +  +     G   D  +       RE       + D+E++ RRG   + +   
Sbjct: 190 LALAMSKEEADQPPSCGPEDDAQLQLALSLSRE-------EHDKEERIRRGDDLRLQMAI 242

Query: 253 EE---ETVTTKHIHITQATET-TTTRHKRTANPSKTIDLGAAAHYTGDKASPDQNASTHT 308
           EE   ET   +   +    +  T      T +P       AAA  T    S         
Sbjct: 243 EESKRETGGKEESSLMDLADVFTAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVP 302

Query: 309 PQSSVKTSVPSSKSSGDLVDLFDGTSQSTGGSADLFGGFADFGSAAASGSFPSQVTATSG 368
           P +        + +SGD        +   G S D +GG      AA  G  P    ++ G
Sbjct: 303 PAADPWGGPAPTPASGDPW----RPAAPAGPSVDPWGGTP--APAAGEGPTPDPWGSSDG 356

Query: 369 NGDFGDWSAFNQAPSGPVASSGEFFGSASQPAV--------------ELVSGSQSALGPP 414
                  SA +     P A S  + GS ++P+               E     +     P
Sbjct: 357 GVPVSGPSASDPWTPAP-AFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALP 415

Query: 415 PAASNSSDLFDLMGSSQATMTSSQSMNFSMMS-TNTVGLGLPMSRSQNTDMVQKSVSKTL 473
            + S++ +L  L G   A    +  M+    S    VG   P +    T   +K+     
Sbjct: 416 TSGSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKT----- 470

Query: 474 PSTWSDPSVN-ISLDNLL-------PGMQPSKPQQPSLN--TMIQQQNMQQPMNVMTQSF 523
           P ++  P+   + LD+L+       PG + S P  P     T     N  QP    T + 
Sbjct: 471 PESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTL 530

Query: 524 GAVNLSSPSNMLPVRPQT--NALIGGP-MPMSMP 554
             + L SP   +P  P T  + L GGP +P  MP
Sbjct: 531 NQLRL-SPVPPVPGAPPTYISPLGGGPGLPPMMP 563


>gi|157388929 epsin 3 [Homo sapiens]
          Length = 632

 Score =  172 bits (435), Expect = 1e-42
 Identities = 159/606 (26%), Positives = 261/606 (43%), Gaps = 81/606 (13%)

Query: 16  NVVMNYSEIESKVREATNDDPWGPSGQLMGEIAKATFMYEQFPELMNMLWSRMLKDNKKN 75
           N+V NYSE E KVREAT++DPWGP   LM EIA  TF    F E+M MLW R L D+ KN
Sbjct: 12  NIVHNYSEAEIKVREATSNDPWGPPSSLMSEIADLTFNTVAFTEVMGMLWRR-LNDSGKN 70

Query: 76  WRRVYKSLLLLAYLIRNGSERVVTSAREHIYDLRSLENYHFVDEHGKDQGINIRQKVKEL 135
           WR VYK+L LL YL++ GSERV    RE++Y +++L+++ ++D  GKDQG+N+R+KVK++
Sbjct: 71  WRHVYKALTLLDYLLKTGSERVAHQCRENLYTIQTLKDFQYIDRDGKDQGVNVREKVKQV 130

Query: 136 VEFAQDDDRLREERKKAKKNKDKY----VGVSSDSVG-GFRYSERYDPEPKSKWDEEWDK 190
           +   +D++RLR+ER  A K K++     +G+ S  +G   RY E Y     S     ++ 
Sbjct: 131 MALLKDEERLRQERTHALKTKERMALEGIGIGSGQLGFSRRYGEDYSRSRGS--PSSYNS 188

Query: 191 NKSAFPFSDKLGELSDKIGSTIDDTISKFRRKDREDSPE------------------RCS 232
           + S+  ++  L +   +     +  +       RE++ +                  R S
Sbjct: 189 SSSSPRYTSDLEQARPQTSGEEELQLQLALAMSREEAEKPVPPASHRDEDLQLQLALRLS 248

Query: 233 DSDEEKKAR--------------------RGRSPKGEFKDEEETVTTKHIHITQATETTT 272
             + EK+ R                    R R P+ E + EEE + T    I    +   
Sbjct: 249 RQEHEKEVRSWQGDGSPMANGAGAVVHHQRDREPEREERKEEEKLKTSQSSILDLADIFV 308

Query: 273 TRHKRTANPSKTIDLGAAAHYTGDKASPDQNASTHTPQSSVKTSVPSS-----KSSGDLV 327
                   P  T          G + + + + S+  P +   + +PS          DL 
Sbjct: 309 P----ALAPPSTHCSADPWDIPGFRPNTEASGSSWGPSADPWSPIPSGTVLSRSQPWDLT 364

Query: 328 DLFDGTSQSTGGSADLFGGFADFGSAAASGSFPSQVTATSGNGDFGDWSAFNQAPSGPVA 387
            +   +S+  G +  L  G       A +   P     ++G   +G     +  P G  A
Sbjct: 365 PML-SSSEPWGRTPVLPAGPPTTDPWALNS--PHHKLPSTGADPWGASLETSDTPGG--A 419

Query: 388 SSGEFFGSASQPAVELVSGSQSALGPPPAASNSSDLFDLMGSSQATMTSSQSMNFSMMST 447
           S+ + F    + + E   G + AL  P    +S    DL G    +   + +     +  
Sbjct: 420 STFDPFAKPPE-STETKEGLEQAL--PSGKPSSPVELDLFGDPSPSSKQNGTKEPDALDL 476

Query: 448 NTVGLGLPMSRSQNTDMVQKSVSKTLPSTWSDPSVN--ISLDNLLPGMQPSKPQQPSLNT 505
             +G  L       T   +++ +   P ++  PS +  ++LD+L+   Q +K + P L  
Sbjct: 477 GILGEAL-------TQPSKEARACRTPESFLGPSASSLVNLDSLVKAPQVAKTRNPFLTG 529

Query: 506 MIQQQNMQQPMNVMTQSFGAVNLSSPS-NMLPVRPQTNALIGGPMPMSMPNVMTGTMGMA 564
           +    +   P    T  FGA     P+ N +        L GGP+   + ++        
Sbjct: 530 L----SAPSP----TNPFGAGEPGRPTLNQMRTGSPALGLAGGPVGAPLGSMTYSASLPL 581

Query: 565 PLGNTP 570
           PL + P
Sbjct: 582 PLSSVP 587


>gi|41350201 epsin 1 isoform c [Homo sapiens]
          Length = 550

 Score =  169 bits (429), Expect = 5e-42
 Identities = 86/175 (49%), Positives = 118/175 (67%), Gaps = 4/175 (2%)

Query: 16  NVVMNYSEIESKVREATNDDPWGPSGQLMGEIAKATFMYEQFPELMNMLWSRMLKDNKKN 75
           N+V NYSE E KVREAT++DPWGPS  LM EIA  T+    F E+M+M+W R L D+ KN
Sbjct: 12  NIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMIWKR-LNDHGKN 70

Query: 76  WRRVYKSLLLLAYLIRNGSERVVTSAREHIYDLRSLENYHFVDEHGKDQGINIRQKVKEL 135
           WR VYK++ L+ YLI+ GSERV    +E++Y +++L+++ +VD  GKDQG+N+R+K K+L
Sbjct: 71  WRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQGVNVREKAKQL 130

Query: 136 VEFAQDDDRLREERKKAKKNKDKY---VGVSSDSVGGFRYSERYDPEPKSKWDEE 187
           V   +D+DRLREER  A K K+K       SS +VG     E     P+S  +EE
Sbjct: 131 VALLRDEDRLREERAHALKTKEKLAQTATASSAAVGSGPPPEAEQAWPQSSGEEE 185


>gi|194272148 epsin 1 isoform a [Homo sapiens]
          Length = 662

 Score =  169 bits (429), Expect = 5e-42
 Identities = 86/175 (49%), Positives = 118/175 (67%), Gaps = 4/175 (2%)

Query: 16  NVVMNYSEIESKVREATNDDPWGPSGQLMGEIAKATFMYEQFPELMNMLWSRMLKDNKKN 75
           N+V NYSE E KVREAT++DPWGPS  LM EIA  T+    F E+M+M+W R L D+ KN
Sbjct: 123 NIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMIWKR-LNDHGKN 181

Query: 76  WRRVYKSLLLLAYLIRNGSERVVTSAREHIYDLRSLENYHFVDEHGKDQGINIRQKVKEL 135
           WR VYK++ L+ YLI+ GSERV    +E++Y +++L+++ +VD  GKDQG+N+R+K K+L
Sbjct: 182 WRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQGVNVREKAKQL 241

Query: 136 VEFAQDDDRLREERKKAKKNKDKY---VGVSSDSVGGFRYSERYDPEPKSKWDEE 187
           V   +D+DRLREER  A K K+K       SS +VG     E     P+S  +EE
Sbjct: 242 VALLRDEDRLREERAHALKTKEKLAQTATASSAAVGSGPPPEAEQAWPQSSGEEE 296


>gi|156671215 epsin 2 isoform b [Homo sapiens]
          Length = 641

 Score =  169 bits (429), Expect = 5e-42
 Identities = 178/653 (27%), Positives = 282/653 (43%), Gaps = 102/653 (15%)

Query: 16  NVVMNYSEIESKVREATNDDPWGPSGQLMGEIAKATFMYEQFPELMNMLWSRMLKDNKKN 75
           N+V NYSE E KVREAT++DPWGPS  LM EIA  T+    F E+M+M+W R L D+ KN
Sbjct: 12  NIVNNYSEAEIKVREATSNDPWGPSSSLMTEIADLTYNVVAFSEIMSMVWKR-LNDHGKN 70

Query: 76  WRRVYKSLLLLAYLIRNGSERVVTSAREHIYDLRSLENYHFVDEHGKDQGINIRQKVKEL 135
           WR VYK+L LL YLI+ GSERV    RE+I+ +++L+++ ++D  GKDQGIN+R+K K+L
Sbjct: 71  WRHVYKALTLLDYLIKTGSERVAQQCRENIFAIQTLKDFQYIDRDGKDQGINVREKSKQL 130

Query: 136 VEFAQDDDRLREERKKAKKNKDKY----VGVSSDSV-----------------------G 168
           V   +D++RL+ ER +A K K++      G+ S+ +                       G
Sbjct: 131 VALLKDEERLKAERAQALKTKERMAQVATGMGSNQITFGRGSSQPNLSTSHSEQEYGKAG 190

Query: 169 GFRYSERYDPE----PKSK------WDEEWDKNKSAFPFSDKLGELSDKIGSTIDDTISK 218
           G   S    PE    P+ +        EE        PF   LG  S   G      ++ 
Sbjct: 191 GSPASYHGSPEASLCPQHRTGAPLGQSEELQPLSQRHPFLPHLGLASRPNGDWSQPCLT- 249

Query: 219 FRRKDREDSPERCSDSDEEKKARRGRSPKGEFKDEEETVTTKHIHITQATETTTTRHKRT 278
             R  R  SP   S+ ++ +    G         EEE      + +++       R +R 
Sbjct: 250 CDRAARATSPRVSSELEQARPQTSG---------EEELQLQLALAMSREVAEQEERLRRG 300

Query: 279 ANPSKTIDLGAAAHYTGDKASPDQNAS--THTPQSSVKTSVPSSKSSGDLVDLFDGTSQS 336
            +    + L  +   T       ++ S    T    +  ++PSS  +    + + G S S
Sbjct: 301 DDLRLQMALEESRRDTVKIPKKKEHGSLPQQTTLLDLMDALPSSGPAAQKAEPW-GPSAS 359

Query: 337 TGGSADLFGGFADFGSAAASGSFPSQVTATSGNGDFGDWSAFNQAPSGPVASSGEFFGSA 396
           T    + +GG A    A AS S P     T        W     A    V  + + + ++
Sbjct: 360 T-NQTNPWGGPA----APASTSDPWPSFGTKPAASIDPWGVPTGATVQSVPKNSDPWAAS 414

Query: 397 SQPAVELVSGSQSALG-----PPPAASNSSDLF-DLMGSSQATMTSSQSMNFSMMSTNTV 450
            QPA      +  A G      P + S S +LF +L G+ +   +   ++  S  +  +V
Sbjct: 415 QQPASSAGKRASDAWGAVSTTKPVSVSGSFELFSNLNGTIKDDFSEFDNLRTSKKTAESV 474

Query: 451 GLGLPMSRSQNTD------------MVQKSVSKTLPSTWSDPSVN-ISLDNLLPGMQPSK 497
              LP   +  T               + S ++  P ++  P+   ++LD+L+   +P+ 
Sbjct: 475 -TSLPSQNNGTTSPDPFESQPLTVASSKPSSARKTPESFLGPNAALVNLDSLV--TRPAP 531

Query: 498 PQQPSLNTMIQ-------------QQNMQQPMNVMTQSFGAVNLSSPSNMLPVRPQTNAL 544
           P Q SLN  +              Q N  QP+  + Q  G+  L + ++  P  P   ++
Sbjct: 532 PAQ-SLNPFLAPGAPATSAPVNPFQVNQPQPL-TLNQLRGSPVLGTSTSFGP-GPGVESM 588

Query: 545 IGGPMPMSMPNVMTGTMG--MAPLGNTPMMNQSMMGMNMNIGMSAAGMGLTGT 595
               M  + P    G  G  + PLG       +MM M  ++G+  +    TGT
Sbjct: 589 AVASMTSAAPQPALGATGSSLTPLG------PAMMNMVGSVGIPPSAAQATGT 635


>gi|31377575 ENTH domain containing 1 [Homo sapiens]
          Length = 607

 Score =  139 bits (351), Expect = 6e-33
 Identities = 69/143 (48%), Positives = 98/143 (68%), Gaps = 1/143 (0%)

Query: 16  NVVMNYSEIESKVREATNDDPWGPSGQLMGEIAKATFMYEQFPELMNMLWSRMLKDNKKN 75
           N V NYS+ E KVREAT++DPWGPS  LM +I+  TF      E+MNMLW R L D+ KN
Sbjct: 9   NFVKNYSDAEIKVREATSNDPWGPSSSLMLDISDLTFNTISLSEIMNMLWHR-LNDHGKN 67

Query: 76  WRRVYKSLLLLAYLIRNGSERVVTSAREHIYDLRSLENYHFVDEHGKDQGINIRQKVKEL 135
           WR VYKSL L+ YLI+NGS++V+   RE   +L++L+++  +DE GKDQG  IR+K K++
Sbjct: 68  WRHVYKSLTLMDYLIKNGSKKVIQHCREGFCNLQTLKDFQHIDEAGKDQGYYIREKSKQV 127

Query: 136 VEFAQDDDRLREERKKAKKNKDK 158
           +    D+  L +ER+ A + + +
Sbjct: 128 ITLLMDEPLLCKEREVACRTRQR 150


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 73/326 (22%), Positives = 127/326 (38%), Gaps = 12/326 (3%)

Query: 163 SSDSVGGFRYSERYDPEPKSKWDEEWDKNKSAFP----FSDKLGELSDKIGSTIDDTISK 218
           SSDS      SE    +  SK D   D N S        SD     +    S   D+   
Sbjct: 619 SSDSKSDSSKSESDSSDSDSKSDSS-DSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDS 677

Query: 219 FRRKDREDSPERCSDSDEEKKARRGRSPKGEFKDEEETVTTKHIHITQATETTTTRHKRT 278
               D  +S +    SD    +    S      D  ++  + + + + +  + ++    +
Sbjct: 678 SSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDS 737

Query: 279 ANPSKTIDLGAAAHYTGDKASPDQNASTHTPQSSVKTSVPSSKSSGDLVDLFDGTSQS-T 337
           +N S + D   +++ +    S D + S+ +  SS  +    S +S D  D  + +  S +
Sbjct: 738 SNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDS 797

Query: 338 GGSADLFGGFADFGSAAASGSFPSQVTATSGNGDFGDWSAFNQAPSGPVASSGEFFGSAS 397
             S+D         S+ +S S  S  + +S + D  D S  N + S   + S +  GS S
Sbjct: 798 SNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSS--NSSDSSDSSDSSD--GSDS 853

Query: 398 QPAVELVSGSQSALGPPPAASNSSDLFDLMGSSQATMT--SSQSMNFSMMSTNTVGLGLP 455
             +    S + S       +SNSSD  D   S++++ +  SS S N S   ++       
Sbjct: 854 DSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSD 913

Query: 456 MSRSQNTDMVQKSVSKTLPSTWSDPS 481
            S S N+    +S + +  S  SD S
Sbjct: 914 SSDSSNSSDSSESSNSSDNSNSSDSS 939



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 70/358 (19%), Positives = 131/358 (36%), Gaps = 13/358 (3%)

Query: 141 DDDRLREERKKAKKNKDKYVGVSSDSVGGFRYSERYDPEPKSKWDEEWDKNKSAFPFSDK 200
           D  +   +   +    D     SSDS      S+  D    S   +  D + S+   S  
Sbjct: 625 DSSKSESDSSDSDSKSDSSDSNSSDSSDN---SDSSDSSNSSNSSDSSDSSDSSDSSSSS 681

Query: 201 LGELSDKIGSTIDDTISKFRRKDREDSPERCSDSDEEKKARRGRSPKGEFKDEEETVTTK 260
               S     + D + S       + S    SDS +   +    S      D  ++  + 
Sbjct: 682 DSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSS 741

Query: 261 HIHITQ--ATETTTTRHKRTANPSKTIDLGAAAHYTGDKASPDQNASTHTPQSSVKTSVP 318
               +   +  + ++    ++N S + D   ++  +    S D N S+++  SS  ++  
Sbjct: 742 DSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSS 801

Query: 319 SSKSSGDLVDLFDGTSQSTGGSADLFGGFADFGSAAASGSFPSQVTATSGNGDFGDWS-A 377
            S +S D  D  D +   +  S+D         S+ +S S  S  ++   + D  + S +
Sbjct: 802 DSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDS 861

Query: 378 FNQAPSGPVASSGEFFGSA-------SQPAVELVSGSQSALGPPPAASNSSDLFDLMGSS 430
            N + S   + S     S+       S  + +    S S+      +SNSSD  D   SS
Sbjct: 862 SNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSS 921

Query: 431 QATMTSSQSMNFSMMSTNTVGLGLPMSRSQNTDMVQKSVSKTLPSTWSDPSVNISLDN 488
            ++ +S+ S N +   ++        S S N+     S   +  S  SD + + S D+
Sbjct: 922 DSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDS 979



 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 80/393 (20%), Positives = 143/393 (36%), Gaps = 14/393 (3%)

Query: 147 EERKKAKKNKDKYVGVSSDSVGGFRYSERYDPEPKSKWDEEWDKNKSAFPFSDKLGELSD 206
           ++  K+   K K     SDS      S+  D    S   +  D N S    SD     SD
Sbjct: 535 DDNDKSDSGKGKSDSSDSDSSDSSNSSDSSD----SSDSDSSDSNSS----SDSDSSDSD 586

Query: 207 KIGSTIDDTISKFRRKDREDSPERCSDSDEEKKA-RRGRSPKGEFKDEEETVTTKHIHIT 265
              S+  D+       D  DS +    SD    +  +  S K E    +    +      
Sbjct: 587 SSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSN 646

Query: 266 QATETTTTRHKRTANPSKTIDLGAAAHYTGDKASPDQNASTHTPQSSVKTSVPSSKSSGD 325
            +  +  +    ++N S + D   ++  +   +S D + S+ +  SS  ++   S  S D
Sbjct: 647 SSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSD 706

Query: 326 LVDL--FDGTSQSTGGSADLFGGFADFGSAAASGSFPSQVTATSGNGDFGDWS-AFNQAP 382
             D    D +  S   S+D     +   S +++ S  S  + +S + D  D S + N + 
Sbjct: 707 SSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSD 766

Query: 383 SGPVASSGEFFGSASQPAVELVSGSQSALGPPPAA--SNSSDLFDLMGSSQATMTSSQSM 440
           S   + S +   S++       S S  +     ++  SNSSD  D   SS +  ++S   
Sbjct: 767 SSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDS 826

Query: 441 NFSMMSTNTVGLGLPMSRSQNTDMVQKSVSKTLPSTWSDPSVNISLDNLLPGMQPSKPQQ 500
           + S  S+++         S ++D      S    S+ S  S + S  +       S    
Sbjct: 827 SNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSN 886

Query: 501 PSLNTMIQQQNMQQPMNVMTQSFGAVNLSSPSN 533
            S N+     +     +  + S  + + S  SN
Sbjct: 887 ESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSN 919



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 59/291 (20%), Positives = 106/291 (36%), Gaps = 6/291 (2%)

Query: 163  SSDSVGGFRYSERYDPEPKSKWDEEWDKNKSAFPFSDKLGELSDKIGSTIDDTISKFRRK 222
            SSDS      S+  D    S   +  D + S+   SD          S   D+       
Sbjct: 743  SSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSS-DSSDSSNSSDSNDSSNSSDSSDSSNSS 801

Query: 223  DREDSPERCSDSDEEKKARRGRSPKGEFKDEEETVTTKHIH----ITQATETTTTRHKRT 278
            D  +S +    SD         S      D  ++  +         +  +++ ++    +
Sbjct: 802  DSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDS 861

Query: 279  ANPSKTIDLGAAAHYTGDKASPDQNASTHTPQSSVKTSVPSSKSSGDLVDLFDGTSQSTG 338
            +N S + D   +++ +    S D N S+++  SS  ++   S SS          S ++ 
Sbjct: 862  SNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSS 921

Query: 339  GSADLFGGFADFGSAAASGSFPSQVTATSGNGDFGDWSAFNQAPSGPVASSGEFFGSASQ 398
             S++      +  S+ +S S  S  ++ S N      S+ +   S    S+      +S 
Sbjct: 922  DSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSN 981

Query: 399  PAVELVSGSQSALGPPPAASNSSDLFDLMGSSQATMTSSQSMNFSMMSTNT 449
             +    S   S       +SNSSD  D   SS ++  SS S N S  S ++
Sbjct: 982  SSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS-NSSDSSNSSDSSNSS 1031



 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 68/323 (21%), Positives = 119/323 (36%), Gaps = 14/323 (4%)

Query: 163  SSDSVGGFRYSERYDPEPKSKWDEEWDKNKSAFPFSDKLGELSDKIGSTIDDTISKFRRK 222
            SSDS      SE  D    S  D     + S           SD   S   D+       
Sbjct: 689  SSDSSDSSNSSESSDSSDSSDSDSSDSSDSSN-------SNSSDSDSSNSSDSSDSSNSS 741

Query: 223  DREDSPERCSDSDEEKKARRGRSPKGEFKDEEETVTTKHIHITQATETTTTRHKRTANPS 282
            D  DS +  + SD    +    S        + + ++   + + + +++ +     ++ S
Sbjct: 742  DSSDSSDSSNSSDSSDSSDSSNSSDSS-DSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNS 800

Query: 283  KTIDLGAAAHYTGDKASPDQNASTHTPQSSVKTSVPSSKSSGDLVDLFDGTSQSTGGSAD 342
                  + +  + D +  D + S+ +  SS  +   +S  S D  D  DG+   +   +D
Sbjct: 801  SDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSD 860

Query: 343  LFGGFADFGSAAASGSFPSQVTA----TSGNGDFGDWSAFNQAPSGPVASSGEFFGSASQ 398
                     S+ +S S  S  ++    +S + D  D S  + + S   ++S +   S S 
Sbjct: 861  SSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDS-SN 919

Query: 399  PAVELVSGSQSALGPPPAASNSSDLFDLMGSSQATMTSSQSMNFSMMSTNTVGLGLPMSR 458
             +    S + S       +SNSSD  D   SS ++  SS S + S  S ++       S 
Sbjct: 920  SSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSS-DSSNSSDSSNSSDSSDSNSSDSSD 978

Query: 459  SQNTDMVQKSVSKTLPSTWSDPS 481
            S N+     S   +  S  SD S
Sbjct: 979  SSNSSDSSDSSDSSDSSDSSDSS 1001



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 63/327 (19%), Positives = 119/327 (36%), Gaps = 10/327 (3%)

Query: 163  SSDSVGGFRYSERYDPEPKSKWDEEWDKNKSAFPFSDKLGELSDKIGSTIDDTISKFRRK 222
            SSDS      S+  D    S      D + S+          SD   S+  D+       
Sbjct: 782  SSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSS--DSSDSSNSS 839

Query: 223  DREDSPERCSDSDEEKKARRGRSPKGEFKDEEETVTTKHIH-ITQATETTTTRHKRTANP 281
            D  DS +    SD +   R   S   +  D  ++  +      + + E++ +     ++ 
Sbjct: 840  DSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSN 899

Query: 282  SKTIDLGAAAHYTGDKASPDQNASTHTPQSSVKTSVPSSKSSGDLVDLFDGTSQS----- 336
            S   D   +++ +    S + + S+ +  SS  ++   S +S D  D  D ++ S     
Sbjct: 900  SSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNS 959

Query: 337  --TGGSADLFGGFADFGSAAASGSFPSQVTATSGNGDFGDWSAFNQAPSGPVASSGEFFG 394
              +  S+D     +   S +++ S  S  + +S + D  D S  + +     +S      
Sbjct: 960  SDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSS 1019

Query: 395  SASQPAVELVSGSQSALGPPPAASNSSDLFDLMGSSQATMTSSQSMNFSMMSTNTVGLGL 454
             +S  +    S   S       +S+SSD  D   SS ++ +S  S +     ++      
Sbjct: 1020 DSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1079

Query: 455  PMSRSQNTDMVQKSVSKTLPSTWSDPS 481
              S S ++     S   +  S  SD S
Sbjct: 1080 DSSESSDSSDSSNSSDSSDSSDSSDSS 1106



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 62/286 (21%), Positives = 106/286 (37%), Gaps = 11/286 (3%)

Query: 163  SSDSVGGFRYSERYDPEPKSKWDEEWDKNKSAFPFSDKLGELSDKIGST----IDDTISK 218
            SSDS      S+  D    S   +    N+S    S    + SD   S+      D+   
Sbjct: 829  SSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNES 888

Query: 219  FRRKDREDSPERCSDSDEEKKARRGRSPKGEFKDEEETVTTKHIHITQATETTTTRHKRT 278
                D  DS    SDSD    +    S       +    +    +   +  + ++    +
Sbjct: 889  SNSSDSSDS-SNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDS 947

Query: 279  ANPSKTIDLGAAAHYTGDKASPDQNASTHTPQSSVKTSVPSSKSSGDLVDLFDGTSQS-- 336
            ++ S + D   ++  +    S D N+S  +  S+   S  SS SS D  D  D ++ S  
Sbjct: 948  SDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSS-DSSDSSDSSNSSDS 1006

Query: 337  --TGGSADLFGGFADFGSAAASGSFPSQVTA-TSGNGDFGDWSAFNQAPSGPVASSGEFF 393
              +  S+D         S+ +S S  S  ++ +S + D  D S  + + +   +S     
Sbjct: 1007 SDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDS 1066

Query: 394  GSASQPAVELVSGSQSALGPPPAASNSSDLFDLMGSSQATMTSSQS 439
              +S  +    S   S       +SNSSD  D   SS ++ +S  S
Sbjct: 1067 SDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSS 1112



 Score = 43.1 bits (100), Expect = 8e-04
 Identities = 57/297 (19%), Positives = 112/297 (37%), Gaps = 18/297 (6%)

Query: 164  SDSVGGFRYSERYDPEPKSKWDEEWDKNKSAFPFSDKLGELSDKIGSTIDDTISKFRRKD 223
            SDS      S+  D    S   +  D N+S+        + SD   S+  D+       D
Sbjct: 859  SDSSNSSDSSDSSDSSNSSDSSDSSDSNESS-----NSSDSSDSSNSSDSDSSDSSNSSD 913

Query: 224  REDSPERCSDSDEEKKARRGRSPKGEFKDEEETVTTKHIHITQATETTTTRHKRTANPSK 283
              DS    SDS E   +    +        + + ++   + + ++ ++ + +   ++ S 
Sbjct: 914  SSDS-SNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSN 972

Query: 284  TIDLGAAAHYTGDKASPDQNASTHTPQSSVKTSVPSSKSSGDLVDLFDGTSQSTGGSADL 343
            + D   +++ +    S D + S+ +  SS  +    S  S D  +  D ++ S   ++  
Sbjct: 973  SSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSD 1032

Query: 344  FGGFADFGSAAASGSFPSQVTATSGNGDFGDWSAFNQAPSGPVASSGEFFGSASQPAVEL 403
                +D  S ++  S  S  + +S + D  D S  + +     +S       +S  +   
Sbjct: 1033 SSDSSD-SSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSS 1091

Query: 404  VSGSQSALGPPPAASNSSDLFDLMGSSQATMTS-----------SQSMNFSMMSTNT 449
             S   S       +S+SSD  D   SS ++ +S           S S N S  S ++
Sbjct: 1092 NSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSS 1148



 Score = 43.1 bits (100), Expect = 8e-04
 Identities = 56/294 (19%), Positives = 107/294 (36%), Gaps = 13/294 (4%)

Query: 163  SSDSVGGFRYSERYDPEPKSKWDEEWDKNKSAFPFSDKLGELSDKIGST----IDDTISK 218
            SSDS      S+  +    S   +  D N S    S    + SD   S+      D+ + 
Sbjct: 944  SSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNS 1003

Query: 219  FRRKDREDSPERCSDSDEEKKARRGRSPKGEFKDEEETVTTKHIHITQATETTTTRHKRT 278
                D  DS +  + SD    +    S       +    +        +  + ++    +
Sbjct: 1004 SDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDS 1063

Query: 279  ANPSKTIDLGAAAHYTGDKASPDQNASTHTPQSSVKTSVPSSKSSGDLVDLFDGTSQS-- 336
            ++ S + D   ++  +    S D + S+++  SS  +    S  S D  D  D +  S  
Sbjct: 1064 SDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNS 1123

Query: 337  --TGGSADLFGGFADFGSAAASGSFPSQVTATSGNGDFGDWSAFNQAPSGPVASSGEFFG 394
              +  S+D     +   S +++ S  S  + +S + D  D S  + +     +S      
Sbjct: 1124 SDSSDSSD-----SSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1178

Query: 395  SASQPAVELVSGSQSALGPPPAASNSSDLFDLMGSSQATMTSSQSMNFSMMSTN 448
            ++S  +    S   S       +S+SSD  D   SS ++ +S  S +     +N
Sbjct: 1179 NSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSN 1232



 Score = 43.1 bits (100), Expect = 8e-04
 Identities = 56/288 (19%), Positives = 95/288 (32%), Gaps = 6/288 (2%)

Query: 163  SSDSVGGFRYSERYDPEPKSKWDEEWDKNKSAFPFSDKLGELSDKIGSTIDDTISKFRRK 222
            SSDS      S+  D    S      D + S    SD          S   D+       
Sbjct: 994  SSDSSDSSNSSDSSDSSDSSDSSNSSDSSNS----SDSSNSSDSSDSSDSSDSSDSSDSS 1049

Query: 223  DREDSPERCSDSDEEKKARRGRSPKGEFKDEEETVTTKHIHITQATETTTTRHKRTANPS 282
            D  DS      SD    +    S       +    +        +  + ++    +++ S
Sbjct: 1050 DSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSS 1109

Query: 283  KTIDLGAAAHYTGDKASPDQNASTHTPQSSVKTSVPSSKSSGDLVDLFDGTSQSTGGSAD 342
             + D   ++  +    S D + S+ +  SS  +    S  S D  D  D +  S    + 
Sbjct: 1110 DSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSS 1169

Query: 343  LFGGFADFGSAAASG--SFPSQVTATSGNGDFGDWSAFNQAPSGPVASSGEFFGSASQPA 400
                 +D  +++ S   S  S  + +S + D  D S  + +     +S       +S  +
Sbjct: 1170 DSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1229

Query: 401  VELVSGSQSALGPPPAASNSSDLFDLMGSSQATMTSSQSMNFSMMSTN 448
                S   S       +SNSSD  D   SS +T  S+   +    S N
Sbjct: 1230 DSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGN 1277



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 60/285 (21%), Positives = 101/285 (35%), Gaps = 22/285 (7%)

Query: 163  SSDSVGGFRYSERYDPEPKSKWDEEWDK----NKSAFPFSDKLGELSDKIGSTIDDTISK 218
            SSDS      S+  +    S   +  D     N S    S      SD   S   D+   
Sbjct: 920  SSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDS 979

Query: 219  FRRKDREDSPERCSDSDEEKKARRGRSPKGEFKDEEETVTTKHIHITQATETTTTRHKRT 278
                D  DS +    SD    +    S   +  D  ++          +  + ++    +
Sbjct: 980  SNSSDSSDSSDSSDSSDSSDSSNS--SDSSDSSDSSDS----------SNSSDSSNSSDS 1027

Query: 279  ANPSKTIDLGAAAHYTGDKASPDQNASTHTPQSSVKTSVPSSKSSGDLVDLFDGTSQS-- 336
            +N S + D   ++  +    S D + S+++  SS  +    S  S D  D  D +  S  
Sbjct: 1028 SNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDS 1087

Query: 337  --TGGSADLFGGFADFGSAAASGSFPSQVTATSGNGDFGDWSAFNQAPSGPVASSGEFFG 394
              +  S+D         S+ +S S  S  ++ S N      S+ +   S    SS     
Sbjct: 1088 SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDS 1147

Query: 395  SASQPAVELVSGSQSALGPPPAASNSSDLFDLMGSSQATMTSSQS 439
            S S  + +    S S+      +S+SSD  D   SS ++ +S  S
Sbjct: 1148 SESSDSSDSSDSSDSS--DSSDSSDSSDSSDSSNSSDSSDSSDSS 1190



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 82/427 (19%), Positives = 151/427 (35%), Gaps = 44/427 (10%)

Query: 120 HGKDQGINIRQKVKELVEFAQDDDRLREERKKAKKNKDKYVGVSSDSVGGFRYSERYDPE 179
           +GKD   N   K +E  +  ++DD             D  +G +SDS       E YDPE
Sbjct: 269 NGKDSSNN--SKGQEGQDHGKEDDH------------DSSIGQNSDS------KEYYDPE 308

Query: 180 PKSKWDEEWDKNKSAFPFSDKLGELSDKIGSTIDDTISKFRRKDREDSPERCSDSDEEKK 239
            K     E D +K++    +  G   D     I+DT  K   ++ +    R +   E   
Sbjct: 309 GKEDPHNEVDGDKTSKSEENSAGIPEDNGSQRIEDT-QKLNHRESKRVENRITKESETHA 367

Query: 240 ARRGRSPKGEFK--DEEETVTTKHIHITQATETTTTRHKRTANPSKTIDLGAAAHYTGDK 297
             + +    E K         TK +      +    +H            G   +  G  
Sbjct: 368 VGKSQDKGIEIKGPSSGNRNITKEVGKGNEGKEDKGQHGMILGKGNVKTQGEVVNIEG-- 425

Query: 298 ASPDQNASTHTPQSSVKTSVPSSKSSGDLVDLFD-----------GTSQSTGGSADLFGG 346
             P Q +    P + V  S   S S+ D  D +D            +S  + G+ D    
Sbjct: 426 --PGQKSE---PGNKVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSE 480

Query: 347 FADFGSAAASGSFPSQVTATSGNGDFGDWSAFNQAPSGPVASSGEFFGSASQPAVELVSG 406
             +  S+    S+ S  +  +GNG     +  + + S    ++ +  G+ +    +    
Sbjct: 481 SDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDD---N 537

Query: 407 SQSALGPPPAASNSSDLFDLMGSSQATMTSSQSMNFSMMSTNTVGLGLPMSRSQNTDMVQ 466
            +S  G   + S+ SD  D   SS ++ +S    + S  S+++       S S ++D   
Sbjct: 538 DKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSD 597

Query: 467 KSVSKTLPSTWSDPSVNISLDNLLPGMQPSKPQQPSLNTMIQQQNMQQPMNVMTQSFGAV 526
            S S     +      + S D+       SK +  S ++  +  +     +  + +  + 
Sbjct: 598 SSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSS 657

Query: 527 NLSSPSN 533
           + S+ SN
Sbjct: 658 DSSNSSN 664



 Score = 39.3 bits (90), Expect = 0.011
 Identities = 57/281 (20%), Positives = 108/281 (38%), Gaps = 6/281 (2%)

Query: 163  SSDSVGGFRYSERYDPEPKSKWDEEWDKNKSAFPFSDKLGELSDKIGSTIDDTIS-KFRR 221
            SSDS      S+  D    S  D     N S    S    + S+   S+ +   S     
Sbjct: 882  SSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNS 941

Query: 222  KDREDSPERCSDSDEEKKARRGRSPKGEFKDEEETVTTKHIHITQATETTTTRHKR-TAN 280
             D  DS +  + SD    +    S   +  D   + ++   + + +++++ +     +++
Sbjct: 942  SDSSDSSDSSNSSDSSNSSDSSNS--SDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSD 999

Query: 281  PSKTIDLGAAAHYTGDKASPDQNASTHTPQSSVKTSVPSSKSSGDLVDLFDGT-SQSTGG 339
             S + D   ++  +    S D + S+ +  SS  +    S  S D  D  D + S ++  
Sbjct: 1000 SSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSD 1059

Query: 340  SADLFGGFADFGSAAASGSFPSQVTA-TSGNGDFGDWSAFNQAPSGPVASSGEFFGSASQ 398
            S+D         S+ +S S  S  ++ +S + +  D S  + +     +S       +S 
Sbjct: 1060 SSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSD 1119

Query: 399  PAVELVSGSQSALGPPPAASNSSDLFDLMGSSQATMTSSQS 439
             +    S   S       +SNSSD  D   SS ++ +S  S
Sbjct: 1120 SSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSS 1160



 Score = 33.1 bits (74), Expect = 0.79
 Identities = 45/222 (20%), Positives = 85/222 (38%), Gaps = 2/222 (0%)

Query: 265 TQATETTTTRHKRTANPSKTIDLGAAAHYTGDKASPDQNASTHTPQSSVKTSVPSSKSSG 324
           +++   +++R   + N  ++ D G  +   G +   D ++++ T  S    +  +     
Sbjct: 479 SESDNNSSSRGDASYNSDESKDNGNGSDSKGAE-DDDSDSTSDTNNSDSNGNGNNGNDDN 537

Query: 325 DLVDLFDGTSQSTGGSADLFGGFADFGSAAASGSFPSQVTATSGNGDFGDWSAFNQAPSG 384
           D  D   G S S+   +      +D   ++ S S  S  ++ S + D     + +   S 
Sbjct: 538 DKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSD 597

Query: 385 PVASSGEFFGSASQPAVELVSGSQSALGPPPAASNSSDLFDLMGSSQATMTSSQSMNFSM 444
              SS     S S  + +    S S      + S+SSD      SS +  + S   + S 
Sbjct: 598 SSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSS 657

Query: 445 MSTNTVGLGLPMSRSQNTDMVQKS-VSKTLPSTWSDPSVNIS 485
            S+N+         S ++D    S  S +  S+ S  S N S
Sbjct: 658 DSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSS 699



 Score = 30.4 bits (67), Expect = 5.1
 Identities = 52/261 (19%), Positives = 88/261 (33%), Gaps = 12/261 (4%)

Query: 163  SSDSVGGFRYSERYDPEPKSKWDEEWDKNKSAFPFSDKLGELSDKIGSTIDDTISKFRRK 222
            SSDS      S+  D    S   +  D + S+   SD          S   D+ +     
Sbjct: 1039 SSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS-DSSDSSDSSDSSESSDSSDSSNSSDSS 1097

Query: 223  DREDSPERCSDSDEEKKARRGRSPKGEFKDEEETVTTKHIHITQATETTTTRHKRTANPS 282
            D  DS +    SD    +    S       +    +        +  + ++    +++ S
Sbjct: 1098 DSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSS 1157

Query: 283  KTIDLGAAAHYTGDKASPDQ-NASTHTPQSSVKTSVPSSKSSGDLVDLFDGTSQSTGGSA 341
             + D   ++  +    S D  N+S  +  S    S  SS SS          S  +  S+
Sbjct: 1158 DSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1217

Query: 342  DLFGGFADFGSAAASGSFPSQVTATSGNGDFGDWSAFNQAPSGPVASSGEFFGSASQPAV 401
            D         S ++  S  S    +S + D  D S  + + S   + S +   S S    
Sbjct: 1218 D--------SSDSSDSSDSSDSNESSDSSDSSDSS--DSSNSSDSSDSSDSSDSTSDSND 1267

Query: 402  ELVSGSQSALGPPPAASNSSD 422
            E  S S+S  G    + + SD
Sbjct: 1268 ESDSQSKSGNGNNNGSDSDSD 1288


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 79/357 (22%), Positives = 139/357 (38%), Gaps = 18/357 (5%)

Query: 71  DNKKNWRRVYKSLLLLAYLIRNGSERVVTSAREHIYDLRSLENYHFVDEHGKDQGINIRQ 130
           D+++  R   + L L   +   G E      +   + L  LE    V+  GK++    R 
Sbjct: 59  DHERKRRVELRCLELEEMMEEQGYEEQQIQEKVATFRLMLLEKD--VNPGGKEETPGQRP 116

Query: 131 KVKELVEFAQDDDRLREERKKAKKNKDKYV-GVSSDSVGGFRYSERYDPEPKSKWD--EE 187
            V E  + A+ +++  E  + A    D YV G S D     R +++  PEP   +    E
Sbjct: 117 AVTETHQLAELNEKKNERLRAAFGISDSYVDGSSFDPQRRAREAKQPAPEPPKPYSLVRE 176

Query: 188 WDKNKSAFPFSDKLGELSDKIGSTIDDTISKFRRKDREDSPERCSDSDEEKKARRGRSPK 247
              ++S  P   K  +  D+ G   + +  +  RK      +  S+S+ +K+  R  +PK
Sbjct: 177 SSSSRSPTPKQKKKKKKKDR-GRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPK 235

Query: 248 GEFKDEEETVTTKHIHITQATETTTTRHKRTANPSKTIDLGAAAHYTGDKASPDQNASTH 307
            + K +++          ++  TT     R A+ S + D  A++  T    S    A TH
Sbjct: 236 SKRKSKDK-------KRKRSRSTTPAPKSRRAHRSTSAD-SASSSDTSRSRSRSAAAKTH 287

Query: 308 TPQSSVKTSVPSS--KSSGDLVDLFDGTSQSTGGSADLFGGFADFGSAAASGSFPSQVTA 365
           T   + ++  P+S  +  GD      GT+ +   S+                    + +A
Sbjct: 288 TTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSA 347

Query: 366 TSGNGDFGDWSAFNQAPSGPVASSGEFFGSASQPAVELVSGSQSALGPPPAASNSSD 422
           T  +    + S+    P  P     E  G + QP +     SQ  + PP  AS + D
Sbjct: 348 TRPSPS-PERSSTGPEPPAPTPLLAERHGGSPQP-LATTPLSQEPVNPPSEASPTRD 402



 Score = 34.7 bits (78), Expect = 0.27
 Identities = 70/332 (21%), Positives = 118/332 (35%), Gaps = 25/332 (7%)

Query: 148 ERKKAKKNKDKYVGVSSDSVGGFRYSERYDPEPKSKWDEEWDKNKSAFPFSDKLGELSDK 207
           ++KK KK KD+  G  S+S    R  ++   + K + + E  K K   P      +  DK
Sbjct: 186 KQKKKKKKKDR--GRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDK 243

Query: 208 IGSTIDDT--ISKFRRKDREDSPERCSDSDEEKKARRGRSPKGEF-----KDEEETVTTK 260
                  T    K RR  R  S +  S SD  +   R  + K        +        +
Sbjct: 244 KRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRR 303

Query: 261 HIHITQATETTTTRHKRTANPSKTIDLGAAAHYTGDKASPDQNASTHTPQSSVKTSVPSS 320
                  +E  TT  +R ++P       ++ +   DK   +++A+  +P     ++ P  
Sbjct: 304 GEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEP 363

Query: 321 KSSGDLVDLFDGTSQSTGGSADLFGGFADFGSAAASGSFPSQVTATSGNGDFGDWSAFNQ 380
            +   L+      ++  GGS       A    +    + PS+ + T       D S    
Sbjct: 364 PAPTPLL------AERHGGSPQ---PLATTPLSQEPVNPPSEASPTR------DRSPPKS 408

Query: 381 APSGPVASSGEFFGSASQPAVELVSGSQSALGPPPAASNSSDLFDLMGSSQATMTSSQSM 440
               P +SS E    + QP       S S   P PA +  S   ++  S  +   S    
Sbjct: 409 PEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHR-EISSSPTSKNRSHGRA 467

Query: 441 NFSMMSTNTVGLGLPMSRSQNTDMVQKSVSKT 472
                 ++T    +  SRS  T    +S S+T
Sbjct: 468 KRDKSHSHTPSRRMGRSRSPATAKRGRSRSRT 499



 Score = 30.8 bits (68), Expect = 3.9
 Identities = 40/172 (23%), Positives = 75/172 (43%), Gaps = 15/172 (8%)

Query: 373  GDWSAFNQAPSGPVASSGEFFGSASQPAVELVSGSQSALGPPPAASNSSDLFDL------ 426
            G  S  + A +   +S+G+  G  S PA  +     S +G PPA++ +     L      
Sbjct: 2471 GSQSLSSGAVATTTSSAGDHNGMLSVPAPGV---PHSDVGEPPASTGAQQPSALAALQPA 2527

Query: 427  ---MGSSQATMTSSQSMNFSMMSTNTVGLGLPMSRSQNTDM-VQKSVS-KTLPSTWSDPS 481
                 SS ++ +SS S + S  S+++   G   S S+ + + VQ  V+ K +PS    P 
Sbjct: 2528 KERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPK 2587

Query: 482  VNISLDNLLPGMQPSKPQQPSLNTMIQQQNMQQPMNVMTQSFGAVNLSSPSN 533
              +  +   P   P+K ++ S ++     +     +  + S  + + SS S+
Sbjct: 2588 EAVR-EGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2638


>gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2
           [Homo sapiens]
          Length = 2191

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 80/321 (24%), Positives = 113/321 (35%), Gaps = 36/321 (11%)

Query: 300 PDQNASTHTPQSSVKTSVPSSKSSGDLV-------DLFDGTSQSTGGSADLFGGFADFGS 352
           P Q+   + PQ  +      ++S   L        DL     +      DL G   D  +
Sbjct: 573 PSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPT 632

Query: 353 AAASGSFPSQVTATSGNGDFGDWSAFNQAPSGPVAS---SGEFFGSASQPAVELVSGSQS 409
              + +  S V+A+      GD S   Q+P  P AS   S    G +  P    V  +QS
Sbjct: 633 GTEA-TLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQS 691

Query: 410 ALGP-PPAASNSSDLFDLMGSSQATMTSSQSMNFSMMSTNTVGLGLPMSRSQNTDMVQKS 468
             GP  PA+   S +      SQ+  +S  +++ S M       G      +N  M Q  
Sbjct: 692 RSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQER---GFMAGTQRNPQMAQYG 748

Query: 469 VSKTLPSTWSDPSVNISLDNLLPGMQPSKPQQPSLNTMIQQQNMQQPMNVMTQSFGAVNL 528
             +T PS    PS    +   +   Q S     S  T   Q +   P           N 
Sbjct: 749 PQQTGPSMSPHPSPGGQMHAGISSFQQSN----SSGTYGPQMSQYGPQG---------NY 795

Query: 529 SSPSNMLPVRPQTNALIGGPMPMSMPNVMTGT-----MGMAPLGNTP---MMNQSMMGMN 580
           S P     V   + +  G  M +S  N M G       G  PLG  P   M N+   G  
Sbjct: 796 SRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNM 855

Query: 581 MNIGMSAAGMGLTGTMGMGMP 601
            ++  S+ GM   G  GMG P
Sbjct: 856 SSMTPSSPGMSQQGGPGMGPP 876



 Score = 35.4 bits (80), Expect = 0.16
 Identities = 46/209 (22%), Positives = 81/209 (38%), Gaps = 21/209 (10%)

Query: 336 STGGSADLFGGFADFGSAAASGSFPSQVTATSGNGDFGDWSAFNQAPSGPVASSGEFFGS 395
           S GG   +  G + F  + +SG++  Q++     G++    A++  PS   +  G   G 
Sbjct: 761 SPGGQ--MHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGI 818

Query: 396 ASQPAVELVSGSQSA----LGPPPAASNSSDLFDLMGSSQATMTSSQSMNFSMMSTNTVG 451
           ++   +     SQ      LG  P+A   +  F     + ++MT S      M      G
Sbjct: 819 SANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFP---GNMSSMTPSSP---GMSQQGGPG 872

Query: 452 LGLPM------SRSQNTDMVQKSVSKTLPSTWSDPSVNIS--LDNLLPGMQPSKPQQPSL 503
           +G PM      ++     ++Q + +       S P +N S  + +  P  QP       +
Sbjct: 873 MGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLM 932

Query: 504 NTMIQQQNMQQPM-NVMTQSFGAVNLSSP 531
           NT     +M   M N    S G  ++ SP
Sbjct: 933 NTQAPPYSMAPAMVNSSAASVGLADMMSP 961



 Score = 30.0 bits (66), Expect = 6.7
 Identities = 65/284 (22%), Positives = 88/284 (30%), Gaps = 26/284 (9%)

Query: 289 AAAHYTGDKASPDQNASTHTPQSSVKT----SVPSSKSSGDLVDLFDGTSQSTGGSADLF 344
           AAA        P QN+    P S        S P +   G       G S   GG     
Sbjct: 213 AAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAG 272

Query: 345 GGFADFGSAAASGSFPSQVTATSGNGDFGDWSAFNQAPSGPVASSGEFFGSASQPAVELV 404
            G A  G+ AA+ +  +      G G +G  SA     S P    G   G    P     
Sbjct: 273 AGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGG---GMMMGPG---- 325

Query: 405 SGSQSALGPPPAASNSSDLFDLMGSSQATMTSSQSMNFSMMSTNTVGLGLPMSRSQNTDM 464
            G  ++L    A S +       G +Q    ++ ++N  + S +      PM RS     
Sbjct: 326 GGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPS------PMMRSYGGSY 379

Query: 465 VQKSVSKTLPSTWSDPSVNISLDNLLPGMQPSKPQQPSLNTMIQQQNMQQPMNVMTQ--S 522
            + S     P   S P    +      G Q +         M  Q     P     Q  S
Sbjct: 380 PEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRS 439

Query: 523 FGAVNLSSPSNMLPVRPQTNALIGGPM-PMSMPNVMTGTMGMAP 565
             A++  +P       P      G PM PM M       MG  P
Sbjct: 440 HPAMSPGTPG------PTMGRSQGSPMDPMVMKRPQLYGMGSNP 477


>gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1
           [Homo sapiens]
          Length = 2231

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 80/321 (24%), Positives = 113/321 (35%), Gaps = 36/321 (11%)

Query: 300 PDQNASTHTPQSSVKTSVPSSKSSGDLV-------DLFDGTSQSTGGSADLFGGFADFGS 352
           P Q+   + PQ  +      ++S   L        DL     +      DL G   D  +
Sbjct: 560 PSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPT 619

Query: 353 AAASGSFPSQVTATSGNGDFGDWSAFNQAPSGPVAS---SGEFFGSASQPAVELVSGSQS 409
              + +  S V+A+      GD S   Q+P  P AS   S    G +  P    V  +QS
Sbjct: 620 GTEA-TLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQS 678

Query: 410 ALGP-PPAASNSSDLFDLMGSSQATMTSSQSMNFSMMSTNTVGLGLPMSRSQNTDMVQKS 468
             GP  PA+   S +      SQ+  +S  +++ S M       G      +N  M Q  
Sbjct: 679 RSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQER---GFMAGTQRNPQMAQYG 735

Query: 469 VSKTLPSTWSDPSVNISLDNLLPGMQPSKPQQPSLNTMIQQQNMQQPMNVMTQSFGAVNL 528
             +T PS    PS    +   +   Q S     S  T   Q +   P           N 
Sbjct: 736 PQQTGPSMSPHPSPGGQMHAGISSFQQSN----SSGTYGPQMSQYGPQG---------NY 782

Query: 529 SSPSNMLPVRPQTNALIGGPMPMSMPNVMTGT-----MGMAPLGNTP---MMNQSMMGMN 580
           S P     V   + +  G  M +S  N M G       G  PLG  P   M N+   G  
Sbjct: 783 SRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNM 842

Query: 581 MNIGMSAAGMGLTGTMGMGMP 601
            ++  S+ GM   G  GMG P
Sbjct: 843 SSMTPSSPGMSQQGGPGMGPP 863



 Score = 36.2 bits (82), Expect = 0.093
 Identities = 56/255 (21%), Positives = 97/255 (38%), Gaps = 28/255 (10%)

Query: 336 STGGSADLFGGFADFGSAAASGSFPSQVTATSGNGDFGDWSAFNQAPSGPVASSGEFFGS 395
           S GG   +  G + F  + +SG++  Q++     G++    A++  PS   +  G   G 
Sbjct: 748 SPGGQ--MHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGI 805

Query: 396 ASQPAVELVSGSQSA----LGPPPAASNSSDLFDLMGSSQATMTSSQSMNFSMMSTNTVG 451
           ++   +     SQ      LG  P+A   +  F     + ++MT S      M      G
Sbjct: 806 SANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFP---GNMSSMTPSSP---GMSQQGGPG 859

Query: 452 LGLPM------SRSQNTDMVQKSVSKTLPSTWSDPSVNIS--LDNLLPGMQPSKPQQPSL 503
           +G PM      ++     ++Q + +       S P +N S  + +  P  QP       +
Sbjct: 860 MGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLM 919

Query: 504 NTMIQQQNMQQPM-NVMTQSFGAVNLSSPSNM---LPVRPQTNALIGGPMPMSMPNVMTG 559
           NT     +M   M N    S G  ++ SP      LP++       G P P S       
Sbjct: 920 NTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKE-EGTPQPESKSKDSYS 978

Query: 560 TMGMA---PLGNTPM 571
           + G++     GN P+
Sbjct: 979 SQGISQPPTPGNLPV 993



 Score = 30.0 bits (66), Expect = 6.7
 Identities = 65/284 (22%), Positives = 88/284 (30%), Gaps = 26/284 (9%)

Query: 289 AAAHYTGDKASPDQNASTHTPQSSVKT----SVPSSKSSGDLVDLFDGTSQSTGGSADLF 344
           AAA        P QN+    P S        S P +   G       G S   GG     
Sbjct: 213 AAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAG 272

Query: 345 GGFADFGSAAASGSFPSQVTATSGNGDFGDWSAFNQAPSGPVASSGEFFGSASQPAVELV 404
            G A  G+ AA+ +  +      G G +G  SA     S P    G   G    P     
Sbjct: 273 AGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGG---GMMMGPG---- 325

Query: 405 SGSQSALGPPPAASNSSDLFDLMGSSQATMTSSQSMNFSMMSTNTVGLGLPMSRSQNTDM 464
            G  ++L    A S +       G +Q    ++ ++N  + S +      PM RS     
Sbjct: 326 GGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPS------PMMRSYGGSY 379

Query: 465 VQKSVSKTLPSTWSDPSVNISLDNLLPGMQPSKPQQPSLNTMIQQQNMQQPMNVMTQ--S 522
            + S     P   S P    +      G Q +         M  Q     P     Q  S
Sbjct: 380 PEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRS 439

Query: 523 FGAVNLSSPSNMLPVRPQTNALIGGPM-PMSMPNVMTGTMGMAP 565
             A++  +P       P      G PM PM M       MG  P
Sbjct: 440 HPAMSPGTPG------PTMGRSQGSPMDPMVMKRPQLYGMGSNP 477


>gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3
           [Homo sapiens]
          Length = 2178

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 80/321 (24%), Positives = 113/321 (35%), Gaps = 36/321 (11%)

Query: 300 PDQNASTHTPQSSVKTSVPSSKSSGDLV-------DLFDGTSQSTGGSADLFGGFADFGS 352
           P Q+   + PQ  +      ++S   L        DL     +      DL G   D  +
Sbjct: 560 PSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPT 619

Query: 353 AAASGSFPSQVTATSGNGDFGDWSAFNQAPSGPVAS---SGEFFGSASQPAVELVSGSQS 409
              + +  S V+A+      GD S   Q+P  P AS   S    G +  P    V  +QS
Sbjct: 620 GTEA-TLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQS 678

Query: 410 ALGP-PPAASNSSDLFDLMGSSQATMTSSQSMNFSMMSTNTVGLGLPMSRSQNTDMVQKS 468
             GP  PA+   S +      SQ+  +S  +++ S M       G      +N  M Q  
Sbjct: 679 RSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQER---GFMAGTQRNPQMAQYG 735

Query: 469 VSKTLPSTWSDPSVNISLDNLLPGMQPSKPQQPSLNTMIQQQNMQQPMNVMTQSFGAVNL 528
             +T PS    PS    +   +   Q S     S  T   Q +   P           N 
Sbjct: 736 PQQTGPSMSPHPSPGGQMHAGISSFQQSN----SSGTYGPQMSQYGPQG---------NY 782

Query: 529 SSPSNMLPVRPQTNALIGGPMPMSMPNVMTGT-----MGMAPLGNTP---MMNQSMMGMN 580
           S P     V   + +  G  M +S  N M G       G  PLG  P   M N+   G  
Sbjct: 783 SRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNM 842

Query: 581 MNIGMSAAGMGLTGTMGMGMP 601
            ++  S+ GM   G  GMG P
Sbjct: 843 SSMTPSSPGMSQQGGPGMGPP 863



 Score = 35.4 bits (80), Expect = 0.16
 Identities = 46/209 (22%), Positives = 81/209 (38%), Gaps = 21/209 (10%)

Query: 336 STGGSADLFGGFADFGSAAASGSFPSQVTATSGNGDFGDWSAFNQAPSGPVASSGEFFGS 395
           S GG   +  G + F  + +SG++  Q++     G++    A++  PS   +  G   G 
Sbjct: 748 SPGGQ--MHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGI 805

Query: 396 ASQPAVELVSGSQSA----LGPPPAASNSSDLFDLMGSSQATMTSSQSMNFSMMSTNTVG 451
           ++   +     SQ      LG  P+A   +  F     + ++MT S      M      G
Sbjct: 806 SANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFP---GNMSSMTPSSP---GMSQQGGPG 859

Query: 452 LGLPM------SRSQNTDMVQKSVSKTLPSTWSDPSVNIS--LDNLLPGMQPSKPQQPSL 503
           +G PM      ++     ++Q + +       S P +N S  + +  P  QP       +
Sbjct: 860 MGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLM 919

Query: 504 NTMIQQQNMQQPM-NVMTQSFGAVNLSSP 531
           NT     +M   M N    S G  ++ SP
Sbjct: 920 NTQAPPYSMAPAMVNSSAASVGLADMMSP 948



 Score = 30.0 bits (66), Expect = 6.7
 Identities = 65/284 (22%), Positives = 88/284 (30%), Gaps = 26/284 (9%)

Query: 289 AAAHYTGDKASPDQNASTHTPQSSVKT----SVPSSKSSGDLVDLFDGTSQSTGGSADLF 344
           AAA        P QN+    P S        S P +   G       G S   GG     
Sbjct: 213 AAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAG 272

Query: 345 GGFADFGSAAASGSFPSQVTATSGNGDFGDWSAFNQAPSGPVASSGEFFGSASQPAVELV 404
            G A  G+ AA+ +  +      G G +G  SA     S P    G   G    P     
Sbjct: 273 AGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGG---GMMMGPG---- 325

Query: 405 SGSQSALGPPPAASNSSDLFDLMGSSQATMTSSQSMNFSMMSTNTVGLGLPMSRSQNTDM 464
            G  ++L    A S +       G +Q    ++ ++N  + S +      PM RS     
Sbjct: 326 GGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPS------PMMRSYGGSY 379

Query: 465 VQKSVSKTLPSTWSDPSVNISLDNLLPGMQPSKPQQPSLNTMIQQQNMQQPMNVMTQ--S 522
            + S     P   S P    +      G Q +         M  Q     P     Q  S
Sbjct: 380 PEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRS 439

Query: 523 FGAVNLSSPSNMLPVRPQTNALIGGPM-PMSMPNVMTGTMGMAP 565
             A++  +P       P      G PM PM M       MG  P
Sbjct: 440 HPAMSPGTPG------PTMGRSQGSPMDPMVMKRPQLYGMGSNP 477


>gi|28559039 mediator complex subunit 1 [Homo sapiens]
          Length = 1581

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 70/297 (23%), Positives = 114/297 (38%), Gaps = 36/297 (12%)

Query: 228  PERCSDSDEEKKARRGRSPKGEFKDEEETVTTKHIHITQATETT--TTRHKRTANPSKTI 285
            P     S     A R ++P G        +T   I I + T      + H +  +     
Sbjct: 1034 PTSTGGSKSPGSAGRSQTPPGVATPPIPKIT---IQIPKGTVMVGKPSSHSQYTSSGSVS 1090

Query: 286  DLGAAAHYTGDKASPDQNASTHTPQSSVKTSVPSSKSSGDLVDLFDGTSQSTGGSADLFG 345
              G+ +H++        ++S+ +  +S    + SSKS G        +  S+ GS+    
Sbjct: 1091 SSGSKSHHS--------HSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSS---- 1138

Query: 346  GFADFGSAAASGSFPSQVTATSGNGDFGDWSAFNQAPSG-------PVASSGEFFGSASQ 398
            G +   +++ SG  P     T      G  S+    P G       P  S      S S+
Sbjct: 1139 GSSQSKNSSQSGGKPGSSPITKHGLSSGS-SSTKMKPQGKPSSLMNPSLSKPNISPSHSR 1197

Query: 399  P---AVELVSGSQSALGPPPAASNSSDLFDLMGSSQATMTSSQSMNFSMMSTNTVGLGLP 455
            P   + +L S  +   G PP++   S +    G S  + TSS S    M S++  GLG  
Sbjct: 1198 PPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSS---GMKSSS--GLGSS 1252

Query: 456  MSRSQNTDMVQKSV---SKTLPSTWSDPSVNISLDNLLPGMQPSKPQQPSLNTMIQQ 509
             S SQ T     S    S +  S+ S  S + +      G  PS+ ++PSL  +I +
Sbjct: 1253 GSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDK 1309



 Score = 35.0 bits (79), Expect = 0.21
 Identities = 79/325 (24%), Positives = 113/325 (34%), Gaps = 69/325 (21%)

Query: 295  GDKASPDQNASTHTPQSSVKTSVPSSKSSGDLVDLFDGTSQSTGGSADLF------GGFA 348
            G  + P + + T +     K   P  K +       +G S S   S   F      GG  
Sbjct: 987  GLDSKPGKRSRTPSNDGKSKDKPPKRKKADT-----EGKSPSHSSSNRPFTPPTSTGGSK 1041

Query: 349  DFGSAAASGSFPSQVTAT---------SGNGDFGDWSAFNQ-APSGPVASSG-EFFGSAS 397
              GSA  S + P   T            G    G  S+ +Q   SG V+SSG +   S S
Sbjct: 1042 SPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSSGSKSHHSHS 1101

Query: 398  QPAVELVSGSQSALGPPPAASNSSDLFDLMGSSQATMTSSQSMNFSMMSTNTVGLGLPMS 457
              +    S S          S+SS L   M SSQ +  SSQS N S         G P S
Sbjct: 1102 SSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSG------GKPGS 1155

Query: 458  RSQNTDMVQKSVSKTLPSTWSDPSVNISLDNLLPGMQPSKPQQPSLNTMIQQQNMQQPMN 517
                            P T    S   S   + P  +PS    PSL+      +  +P  
Sbjct: 1156 S---------------PITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPG 1200

Query: 518  VMTQSFGAVNLSSPSNMLPVRPQTNALIGGPMPMSMPNVMTGTMGMAPLGNTPMMNQSMM 577
                  G+  L+SP   +P  P        P   +   + +G+ G             M 
Sbjct: 1201 ------GSDKLASPMKPVPGTP--------PSSKAKSPISSGSGG-----------SHMS 1235

Query: 578  GMNMNIGM-SAAGMGLTGTMGMGMP 601
            G + + GM S++G+G +G++    P
Sbjct: 1236 GTSSSSGMKSSSGLGSSGSLSQKTP 1260


>gi|151301154 mucin 6, gastric [Homo sapiens]
          Length = 2439

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 76/329 (23%), Positives = 119/329 (36%), Gaps = 42/329 (12%)

Query: 245  SPKGEFKDEEETVTTKHIHITQATETTTTRHKRTANPSKTIDLGAAAHYTGDKASPDQNA 304
            +P G          T   H       TT+   +T +   T    A++ +    +   QN+
Sbjct: 2041 TPTGTVPPPTTLKATGSTHTAPPMTVTTSGTSQTHSSFSTAT--ASSSFISSSSWLPQNS 2098

Query: 305  STHTPQSSVKTSVPSSKSSGDLVDLFDGTSQSTGGSADLFGGFADFGSAAASGSFPSQVT 364
            S+  P S + T +P   S+   V     T+Q                    S SF    +
Sbjct: 2099 SSRPPSSPITTQLPHLSSATTPVST---TNQ-------------------LSSSFSPSPS 2136

Query: 365  ATSGNGDFGDWSAFNQAPSGPVASSGEFFGSASQPAVELVSGSQSALG--PPPAASNSSD 422
            A S    +   S  +   S P   +   F SA   +  L SGS S+L   P  A+ ++S 
Sbjct: 2137 APSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVSASP 2196

Query: 423  LFDLMGSSQATMTSSQSMNFSMMSTNTVGLGLPMSRSQNTDMVQKSVSKTL-PSTWSDPS 481
            LF    S  A+ T   ++  ++ S  T+   LP+S    T  V  + S  L  ST + PS
Sbjct: 2197 LFP--SSPAASTTIRATLPHTISSPFTLSALLPIS----TVTVSPTPSSHLASSTIAFPS 2250

Query: 482  VNISLDNLLPGMQPSKPQQPSLNTMIQQQNMQQPMNVMTQSFGAVNLSSPSNMLPVRPQT 541
                     P    S    P+ ++     +    +     + G V+L+S    +P  P T
Sbjct: 2251 T--------PRTTASTHTAPAFSSQ-STTSRSTSLTTRVPTSGFVSLTSGVTGIPTSPVT 2301

Query: 542  NALIGGPMPMSMPNVMTGTMGMAPLGNTP 570
            N     P P   P     T  +   G+TP
Sbjct: 2302 NLTTRHPGPTLSPTTRFLTSSLTAHGSTP 2330



 Score = 31.6 bits (70), Expect = 2.3
 Identities = 23/93 (24%), Positives = 36/93 (38%), Gaps = 6/93 (6%)

Query: 490  LPGMQPSKPQQPSLNTMIQQQNMQQPMNVMTQSFGAVNLSSP---SNMLPVRPQTNALIG 546
            +P   P  P  P L T   +     PM   + + G ++ + P   SN  P  P    L+ 
Sbjct: 1197 MPPTTPQPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQTPLLP 1256

Query: 547  GPMPMSMPNVMTGTMGMAPLGNTPMMNQSMMGM 579
              +  S P   T + G  P   T +  Q+  G+
Sbjct: 1257 ATLTSSKP---TASSGEPPRPTTAVTPQATSGL 1286


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 85/441 (19%), Positives = 155/441 (35%), Gaps = 34/441 (7%)

Query: 179  EPKSKWDEEWDKNKSAFPFSDKLGELSDKIGSTIDDTISKFRRKDREDSPERCSDSDEEK 238
            EP +          +A P S     LS+K  +      S  R  D   SP   + S   +
Sbjct: 1662 EPTTSPISSGSTETTALPGSTTTAGLSEKSTTFY----SSPRSPDTTLSPASTTSSGVSE 1717

Query: 239  KARRGRSPKGEFKDEEETVTTKHIHITQATETTTTRHKRTANPSKTIDLGAAAHYTGDKA 298
            ++    S  G       T       +   ++ +T  H    +   T+  G+    T    
Sbjct: 1718 ESTTSHSRPGS---THTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGST---TASSL 1771

Query: 299  SPDQNASTHTPQSSVKTSVPSSKSSGDLVDLFDGTSQSTG---------GSADLFGGFAD 349
             P+      +P S+  T +P + ++  L++       STG         GS    G    
Sbjct: 1772 GPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTT 1831

Query: 350  FGSAAAS-GSFPSQVTATSGNGDFGDWS--AFNQAPSGPVASSGEFFGSASQPAVELVSG 406
            F S  +S  + P+  T TS   +    S  + +  P+   ++S    G + +      S 
Sbjct: 1832 FQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSP 1891

Query: 407  SQSALGPPPAASNSSDLFDLMGSSQATMTSSQSMNFSMMSTNTVGLGLPMSRSQNTDMVQ 466
              +A  P PA S +S L +   +  ++  S+Q+M+F   ST +        RS+ +    
Sbjct: 1892 VATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTAS-------GRSEESRTSH 1944

Query: 467  KSVSKTLPSTWSDPSVNISLDNLLPGMQPSKPQQPSLNTMIQQQNMQQPMNVMTQSFGAV 526
             S + T+ S  S  S  +      P    S P   +                 T S  + 
Sbjct: 1945 SSTTHTISSPPSTTSALVE----EPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQ 2000

Query: 527  NLSSPSNMLPVRPQTNALIGGPMPMSMPNVMTGTMGMAPLGNTPMMNQSMMGMNMNIGMS 586
            + ++ + +LP R  T+ L+G      + +    T  +     TP +++     + +    
Sbjct: 2001 D-ATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSP 2059

Query: 587  AAGMGLTGTMGMGMPNIAMTS 607
            A  +    T   G+   + TS
Sbjct: 2060 ATTLSPASTTSSGVSEESTTS 2080



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 75/380 (19%), Positives = 134/380 (35%), Gaps = 34/380 (8%)

Query: 179  EPKSKWDEEWDKNKSAFPFSDKLGELSDKIGSTIDDTISKFRRKDREDSPERCSDSDEEK 238
            EP +          +A P S     LS+K  +      S  R  D   SP   + S   +
Sbjct: 4302 EPTTSPISSGSTETTALPGSTTTAGLSEKSTTFY----SSPRSPDTTLSPASTTSSGVSE 4357

Query: 239  KARRGRSPKGEFKDEEETVTTKHIHITQATETTTTRHKRTANPSKTIDLGAAAHYTGDKA 298
            ++    S  G       T       +   ++ +T  H    +   T+  G+    T    
Sbjct: 4358 ESTTSHSRPGSM---HTTAFPSSTTMPGVSQESTASHSSPGSTDTTLSPGST---TASSL 4411

Query: 299  SPDQNASTHTPQSSVKTSVPSSKSSGDLVDLFDGTSQSTG---------GSADLFGGFAD 349
             P+      +P S+  T +P + ++  L++       STG         GS    G    
Sbjct: 4412 GPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTT 4471

Query: 350  FGSAAAS-GSFPSQVTATSGNGDFGDWS--AFNQAPSGPVASSGEFFGSASQPAVELVSG 406
            F S   S  + P+  T TS   +    S  + +  P+   ++S    G + +      S 
Sbjct: 4472 FQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSP 4531

Query: 407  SQSALGPPPAASNSSDLFDLMGSSQATMTSSQSMNFSMMSTNTVGLGLPMSRSQNTDMVQ 466
              +A  P PA S +S L +   +  ++  S+Q+M+F   +T +        R + +    
Sbjct: 4532 VATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESNTTS-------GRGEESTTSH 4584

Query: 467  KSVSKTLPSTWSDPSVNISLDNLLPGMQPSKPQQPSLNTMIQQQNMQQPMNVMTQSFGAV 526
             S + T+ S  S  S  +      P    S P   +                 T S  + 
Sbjct: 4585 SSTTHTISSAPSTTSALVE----EPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQ 4640

Query: 527  NLSSPSNMLPVRPQTNALIG 546
            + ++ + +LP R  T+ L+G
Sbjct: 4641 D-ATGTIVLPARSTTSVLLG 4659



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 74/377 (19%), Positives = 133/377 (35%), Gaps = 49/377 (12%)

Query: 268  TETTTTRHKR------TANPSKTIDLGAAAHYTGDKASPDQNASTHTPQSSVKTSV---- 317
            +E +TT H R      TA P  T   G +   T   +SP    +T +P S+  +S+    
Sbjct: 3273 SEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPES 3332

Query: 318  ---------------PSSKSSGDLVDLFDGTSQSTG---------GSADLFGGFADFGSA 353
                           P + ++  L++       STG         GS    G    F S 
Sbjct: 3333 TTFHSGPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSW 3392

Query: 354  AAS-GSFPSQVTATSGNGDFGDWS--AFNQAPSGPVASSGEFFGSASQPAVELVSGSQSA 410
              S  + P+  T TS   +    S  + +  P+   ++S    G + +      S   +A
Sbjct: 3393 PNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATA 3452

Query: 411  LGPPPAASNSSDLFDLMGSSQATMTSSQSMNFSMMSTNTVGLGLPMSRSQNTDMVQKSVS 470
              P PA S +S L +   +  ++  S+Q+M+F    T +        R + +     S +
Sbjct: 3453 TTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTS-------GRGEESTTSHSSTT 3505

Query: 471  KTLPSTWSDPSVNISLDNLLPGMQPSKPQQPSLNTMIQQQNMQQPMNVMTQSFGAVNLSS 530
             T+ S  S  S  +      P    S P   +                 T S  + + ++
Sbjct: 3506 HTISSAPSTTSALVE----EPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQD-AT 3560

Query: 531  PSNMLPVRPQTNALIGGPMPMSMPNVMTGTMGMAPLGNTPMMNQSMMGMNMNIGMSAAGM 590
             + +LP R  T+ L+G      + +    T  +     TP +++     + +    A  +
Sbjct: 3561 GTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTL 3620

Query: 591  GLTGTMGMGMPNIAMTS 607
                T   G+   + TS
Sbjct: 3621 SPASTTSSGVSEESTTS 3637



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 87/420 (20%), Positives = 147/420 (35%), Gaps = 49/420 (11%)

Query: 179 EPKSKWDEEWDKNKSAFPFSDKLGELSDKIGSTIDDTISKFRRKDREDSPERCSDSDEEK 238
           EPK+          +A P S     LS+K  +      S  R  DR  SP R + S   +
Sbjct: 251 EPKTSPITSASMETTALPGSTTTAGLSEKSTTFY----SSPRSPDRTLSPARTTSSGVSE 306

Query: 239 KARRGRSPKGEFKDEEETVTTKHIHITQATETTTTRHKRTANPSKTIDLGAAAHYTGDKA 298
           K+    S  G         +T    ++Q +   T  H    +   T+  G     T    
Sbjct: 307 KSTTSHSRPGPTHTIAFPDSTTMPGVSQES---TASHSIPGSTDTTLSPGTT---TPSSL 360

Query: 299 SPDQNASTHTPQSSVKTSVPSSKSSGDLVDLFDGTSQSTGG--------SADLFGG---- 346
            P+      +P  +  T +P + ++  L++       STG         S+    G    
Sbjct: 361 GPESTTFHSSPGYTKTTRLPDNTTTSGLLEASTPVHSSTGSPHTTLSPSSSTTHEGEPTT 420

Query: 347 FADFGSAAASGSFPSQVTATSGNGDFGDWSAFNQAPSGPVASSGEFFGSASQPAVELVSG 406
           F  + S+  +   PS  T+          S+ +  P+   ++S    G + +      S 
Sbjct: 421 FQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPVHSSP 480

Query: 407 SQSALGPPPAASNSSDLFDLMGSSQATMTSSQSMNFSMMSTNTVGLGLPMSRSQNTDMVQ 466
             +A  PPPA S +S   +   +   +  S+Q+M+F   ST +         S+ +    
Sbjct: 481 VATATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPESSTTS-------GHSEESATFH 533

Query: 467 KSVSKTLPSTWSDPSVNISLDNLLPGMQPSKPQQPSLNTMIQQQNMQQPMNVMTQSFGAV 526
            S + T  ST   PS   +L               S ++ +         +  T S G  
Sbjct: 534 GSTTHTKSST---PSTTAAL------------AHTSYHSSLGSTETTHFRDSSTIS-GRS 577

Query: 527 NLSSPSNMLPVRPQTNALIGGPMPMSMPNVMTGTMGMAPLGNTPMMNQSMMGMNMNIGMS 586
             S  S+  P    T  L  G    S P+V+ G    +P+ +  M   ++ G     G+S
Sbjct: 578 EESKASHSSPDAMATTVLPAG----STPSVLVGDSTPSPISSGSMETTALPGSTTKPGLS 633



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 69/352 (19%), Positives = 127/352 (36%), Gaps = 39/352 (11%)

Query: 254  EETVTTKHIHITQATETTTTRHKRTANPSKTIDLGAAAHYTGDKASPDQNASTHTPQSSV 313
            + T ++  +  +    ++T   + T +P+ +   G     T  +  P    +T +P S+ 
Sbjct: 3735 DSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTA 3794

Query: 314  KTSVPSS----KSSGDLVDLFDGTSQSTGGSADLFGGFADFGSAAASGSFPSQV-TATSG 368
               V  S    +S G         S +T G ++    F    S  ASG+ PS   + TSG
Sbjct: 3795 TAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIF--HSSPDASGTTPSSAHSTTSG 3852

Query: 369  NGDF-------GDWSAFNQAPS----GPVASSGEFFGSASQPAVELVSGSQSALGPPPAA 417
             G+        G         S    G   +S  F+ S   P   L   S ++LG    +
Sbjct: 3853 RGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEES 3912

Query: 418  SNSSDLFDLMGSSQATMTSSQSMNFSMMSTNTVGLGLPMSRSQNTDMVQK---SVSKTLP 474
            + S       GS+ +T++ + +    +   +T         ++ T   +    SV +  P
Sbjct: 3913 TTSRSQ---PGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRREEP 3969

Query: 475  STW-----SDPSVNISLDNLLPGMQPSKPQQPSLNTMIQQQNMQQPMNVMTQSFGAVNLS 529
            +T+     S  +   + D+   G+       P      Q      P  + T   G  + +
Sbjct: 3970 TTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTG---LPATLTTADLGEESTT 4026

Query: 530  SPSN-------MLPVRPQTNALIGGPMPMSMPNVMTGTMGMAPLGNTPMMNQ 574
             PS+       + P R  T+ L+G   P  +    T T  +     TP +++
Sbjct: 4027 FPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSE 4078



 Score = 39.3 bits (90), Expect = 0.011
 Identities = 63/265 (23%), Positives = 107/265 (40%), Gaps = 24/265 (9%)

Query: 227  SPERCSDSDEEKKARRGRSPKGEFKDEE--ETVTTKHIHITQATETTTTRHKRTANPSKT 284
            SP R + S   +++    S  G  +     E+ TT        T  ++T H  ++ PS T
Sbjct: 4539 SPARSTTSGLVEESTTYHSSPGSTQTMHFPESNTTSGRGEESTTSHSSTTHTISSAPSTT 4598

Query: 285  IDLGAAAHYTGDKASPDQNASTHTPQSSVKTS----VPSSKSSGDLVDLFDGTSQSTGGS 340
              L      T   +SP   A+TH P SS  +       +S SS D        ++ST  +
Sbjct: 4599 SAL--VEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARST--T 4654

Query: 341  ADLFGGFADFGSAAASGSFPSQVTATSGNGDFGDWSAFNQAPSGP----VASSGEFFGSA 396
            + L G       ++ S    +   +T+  G     + F+ +PS       ++S    G +
Sbjct: 4655 SVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPSSTPTTHFSASSTTLGRS 4714

Query: 397  SQPAVELVSGSQSALGPPPAASNSSDLFDLMGSSQATMTSSQSMNFSMMSTNTVGLGLPM 456
             +      S   +A  P PA S +S L +   +  ++  S+Q+M+F   ST +       
Sbjct: 4715 EESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTAS------- 4767

Query: 457  SRSQNTDMVQKSVSKTL---PSTWS 478
             RS+ +     S + T+   PST S
Sbjct: 4768 GRSEESRTSHSSTTHTISSPPSTTS 4792



 Score = 38.5 bits (88), Expect = 0.019
 Identities = 69/352 (19%), Positives = 125/352 (35%), Gaps = 39/352 (11%)

Query: 254  EETVTTKHIHITQATETTTTRHKRTANPSKTIDLGAAAHYTGDKASPDQNASTHTPQSSV 313
            + T ++  +  +    ++T   + T +P+ +   G     T  +  P    +T +P S+ 
Sbjct: 1095 DSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTA 1154

Query: 314  KTSVPSS----KSSGDLVDLFDGTSQSTGGSADLFGGFADFGSAAASGSFPSQV-TATSG 368
               V  S    +S G         S +T G ++    F    S  ASG+ PS   + TSG
Sbjct: 1155 TAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIF--HSSPDASGTTPSSAHSTTSG 1212

Query: 369  NGDF-------GDWSAFNQAPS----GPVASSGEFFGSASQPAVELVSGSQSALGPPPAA 417
             G+        G         S    G   +S  F+ S   P   L   S ++LG    +
Sbjct: 1213 RGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEES 1272

Query: 418  SNSSDLFDLMGSSQATMTSSQSMNFSMMSTNTVGLGLPMSRSQNT---DMVQKSVSKTLP 474
            + S       GS+ +T++ + +    +   +T         ++ T        SV    P
Sbjct: 1273 TTSRSQ---PGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEP 1329

Query: 475  STW-----SDPSVNISLDNLLPGMQPSKPQQPSLNTMIQQQNMQQPMNVMTQSFGAVNLS 529
            +T+     S  +   + D+   G+       P      Q      P  + T   G  + +
Sbjct: 1330 TTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTG---LPATLTTADLGEESTT 1386

Query: 530  SPSN-------MLPVRPQTNALIGGPMPMSMPNVMTGTMGMAPLGNTPMMNQ 574
             PS+       + P R  T+ L+G   P  +    T T  +     TP +++
Sbjct: 1387 FPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSE 1438



 Score = 37.7 bits (86), Expect = 0.032
 Identities = 69/352 (19%), Positives = 126/352 (35%), Gaps = 39/352 (11%)

Query: 254  EETVTTKHIHITQATETTTTRHKRTANPSKTIDLGAAAHYTGDKASPDQNASTHTPQSSV 313
            + T ++  +  +    ++T   + T +P+ +   G     T  +  P    +T +P S+ 
Sbjct: 2178 DSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTA 2237

Query: 314  KTSVPSS----KSSGDLVDLFDGTSQSTGGSADLFGGFADFGSAAASGSFPSQV-TATSG 368
               V  S    +S G         S +T G ++    F    S  ASG+ PS   + TSG
Sbjct: 2238 TAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIF--HSSPDASGTTPSSAHSTTSG 2295

Query: 369  NGDF-------GDWSAFNQAPS----GPVASSGEFFGSASQPAVELVSGSQSALGPPPAA 417
             G+        G         S    G   +S  F+ S   P   L   S ++LG    +
Sbjct: 2296 RGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEES 2355

Query: 418  SNSSDLFDLMGSSQATMTSSQSMNFSMMSTNTVGLGLPMSRSQNTDMVQK---SVSKTLP 474
            + S       GS+ +T++ + +    +   +T         ++ T   +    SV    P
Sbjct: 2356 TTSRSQ---PGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRTPTTSVRGEEP 2412

Query: 475  STW-----SDPSVNISLDNLLPGMQPSKPQQPSLNTMIQQQNMQQPMNVMTQSFGAVNLS 529
            +T+     S  +   + D+   G+       P      Q      P  + T   G  + +
Sbjct: 2413 TTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTG---LPATLTTADLGEESTT 2469

Query: 530  SPSN-------MLPVRPQTNALIGGPMPMSMPNVMTGTMGMAPLGNTPMMNQ 574
             PS+       + P R  T+ L+G   P  +    T T  +     TP +++
Sbjct: 2470 FPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSE 2521



 Score = 37.4 bits (85), Expect = 0.042
 Identities = 69/352 (19%), Positives = 126/352 (35%), Gaps = 39/352 (11%)

Query: 254  EETVTTKHIHITQATETTTTRHKRTANPSKTIDLGAAAHYTGDKASPDQNASTHTPQSSV 313
            + T ++  +  +    ++T   + T +P+ +   G     T  +  P    +T +P S+ 
Sbjct: 2652 DSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTTFQTHPASTHTTPSPPSTA 2711

Query: 314  KTSVPSS----KSSGDLVDLFDGTSQSTGGSADLFGGFADFGSAAASGSFPSQV-TATSG 368
               V  S    +S G         S +T G ++    F    S  ASG+ PS   + TSG
Sbjct: 2712 TAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIF--HSSPDASGTTPSSAHSTTSG 2769

Query: 369  NGDF-------GDWSAFNQAPS----GPVASSGEFFGSASQPAVELVSGSQSALGPPPAA 417
             G+        G         S    G   +S  F+ S   P   L   S ++LG    +
Sbjct: 2770 RGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEES 2829

Query: 418  SNSSDLFDLMGSSQATMTSSQSMNFSMMSTNTVGLGLPMSRSQNTDMVQK---SVSKTLP 474
            + S       GS+ +T++ + +    +   +T         ++ T   +    SV    P
Sbjct: 2830 TTSRSQ---PGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRGEEP 2886

Query: 475  STW-----SDPSVNISLDNLLPGMQPSKPQQPSLNTMIQQQNMQQPMNVMTQSFGAVNLS 529
            +T+     S  +   + D+   G+       P      Q      P  + T   G  + +
Sbjct: 2887 TTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTG---LPATLTTADLGEESTT 2943

Query: 530  SPSN-------MLPVRPQTNALIGGPMPMSMPNVMTGTMGMAPLGNTPMMNQ 574
             PS+       + P R  T+ L+G   P  +    T T  +     TP +++
Sbjct: 2944 FPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSE 2995



 Score = 36.6 bits (83), Expect = 0.071
 Identities = 48/178 (26%), Positives = 67/178 (37%), Gaps = 25/178 (14%)

Query: 269  ETTTTRHK-----RTANPSKTIDLGAAAHYTGDKASPDQNASTHTPQSSVKTSVPSSKSS 323
            E+TT+R +      TA P  T   G + H T   +SP    +T  P +S  TS PS +S+
Sbjct: 993  ESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLP-ASTTTSGPSQEST 1051

Query: 324  GDLVDLFDGTSQSTGGSADLFGGFADFGSAAASGSFPSQVTATSGNGDFGDWSAF--NQA 381
                     TS S+ GS D     A    +  + SF  + T    N      + F  +  
Sbjct: 1052 ---------TSHSSSGSTDT----ALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTT 1098

Query: 382  PSGPVASSGEFFGSASQPAVELVSGSQSALGPPPAASNSSDLFDLMGSSQATMTSSQS 439
             SG V +S     S   P   L   S ++    P     S  F    +S  T  S  S
Sbjct: 1099 SSGIVEASTRVHSSTGSPRTTLSPASSTS----PGLQGESTAFQTHPASTHTTPSPPS 1152



 Score = 36.6 bits (83), Expect = 0.071
 Identities = 52/183 (28%), Positives = 69/183 (37%), Gaps = 41/183 (22%)

Query: 268  TETTTTRHKR------TANPSKTIDLGAAAHYTGDKASPDQNASTHTPQSSVKTSVPSSK 321
            +E +TT H R      TA P  T   G + H T   +SP    +T  P +S  TS PS +
Sbjct: 2074 SEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLP-ASTTTSGPSQE 2132

Query: 322  SSGDLVDLFDGTSQSTGGSADLFGGFADFGSAAASGSFPSQVTATSGNGDFGDWSAFNQA 381
            S+         TS S+ GS D             +   P   TA S    FG  S    +
Sbjct: 2133 ST---------TSHSSPGSTD-------------TALSPGSTTALS----FGQESTTFHS 2166

Query: 382  PSGPVASSGEFFGSASQPAVELVSGSQSALGPP-----PAASNSSDLFDLMGSSQATMTS 436
              G   ++     + S   VE  +   S+ G P     PA+S S     L G S A  T 
Sbjct: 2167 SPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSP---GLQGESTAFQTH 2223

Query: 437  SQS 439
              S
Sbjct: 2224 PAS 2226



 Score = 35.8 bits (81), Expect = 0.12
 Identities = 60/252 (23%), Positives = 85/252 (33%), Gaps = 33/252 (13%)

Query: 205  SDKIGSTIDDTISKFRRKDREDSPERCSDSDEEKKARRGRSPKGEFKDEEETVTTK---- 260
            S   G+T+    S       E +P R S S  E     G        ++  T  T     
Sbjct: 2474 SGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSP 2533

Query: 261  HIHITQATETTT-------TRHKR------TANPSKTIDLGAAAHYTGDKASPDQNASTH 307
               ++ AT T++       T H +      TA P  T   G + H T   +SP    +T 
Sbjct: 2534 DATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTL 2593

Query: 308  TPQSSVKTSVPSSKSSGDLVDLFDGTSQSTGGSADLFGGFADFGSAAASGSFPSQVTATS 367
             P +S  TS PS +S+         TS S+ GS D     +   + A S    S    +S
Sbjct: 2594 LP-ASTTTSGPSQEST---------TSHSSPGSTDT--ALSPGSTTALSFGQESTTFHSS 2641

Query: 368  GNGDFGDWSAFNQAPSGPVASSGEFFGSASQPAVELVSGSQSALGPPPAASNSSDLFDLM 427
                       +   SG V +S     S   P   L   S ++    P     S  F   
Sbjct: 2642 PGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTS----PGLQGESTTFQTH 2697

Query: 428  GSSQATMTSSQS 439
             +S  T  S  S
Sbjct: 2698 PASTHTTPSPPS 2709



 Score = 34.7 bits (78), Expect = 0.27
 Identities = 69/332 (20%), Positives = 119/332 (35%), Gaps = 33/332 (9%)

Query: 256 TVTTKHIHITQATETTTTRHKRTANPSKTIDLGAAAHYTGDKASPDQNASTHTPQSSVKT 315
           + T  H   +    ++      T  P+++   G     T    SP    + H P+SS  T
Sbjct: 464 STTLGHSEESTPVHSSPVATATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPESST-T 522

Query: 316 SVPSSKSSGDLVDLFDGTSQSTGGSADLFGGFADFGSAAASGSFPSQVTATSGNGDFGDW 375
           S  S +S+      F G++  T  S           +A A  S+ S + +T     F D 
Sbjct: 523 SGHSEESA-----TFHGSTTHTKSSTP------STTAALAHTSYHSSLGSTETT-HFRDS 570

Query: 376 SAFN-------QAPSGPVASSGEFFGSASQPAVELVSGSQSALGPPPAASNSSDLFDLMG 428
           S  +        + S P A +     + S P+V LV  S     P P +S S +   L G
Sbjct: 571 STISGRSEESKASHSSPDAMATTVLPAGSTPSV-LVGDST----PSPISSGSMETTALPG 625

Query: 429 SSQATMTSSQSMNFSMMSTNTVGLGLPMSRSQNTDMVQKSVSKTLPSTWSDPSVNISLDN 488
           S+     S +S  F     +     LP S + +    + + S + P   S  +       
Sbjct: 626 STTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPG--STHTTAFPGST 683

Query: 489 LLPGMQPSKPQQ-----PSLNTMIQQQNMQQPMNVMTQSFGAVNLSSPSNMLPVRPQTNA 543
            +PG+            P+  T+         +     +F +   S+ + +LP     + 
Sbjct: 684 TMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASG 743

Query: 544 LIGGPMPMSMPNVMTGTMGMAPLGNTPMMNQS 575
           L+   MP+        T  ++P G+T    +S
Sbjct: 744 LLEASMPVHSSTRSPHTT-LSPAGSTTRQGES 774



 Score = 34.3 bits (77), Expect = 0.35
 Identities = 51/183 (27%), Positives = 68/183 (37%), Gaps = 41/183 (22%)

Query: 268  TETTTTRHKR------TANPSKTIDLGAAAHYTGDKASPDQNASTHTPQSSVKTSVPSSK 321
            +E +TT H R      TA P  T   G + H T   +SP    +T  P +S  TS  S +
Sbjct: 3631 SEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLP-ASTTTSGSSQE 3689

Query: 322  SSGDLVDLFDGTSQSTGGSADLFGGFADFGSAAASGSFPSQVTATSGNGDFGDWSAFNQA 381
            S+         TS S+ GS D             +   P   TA S    FG  S    +
Sbjct: 3690 ST---------TSHSSSGSTD-------------TALSPGSTTALS----FGQESTTFHS 3723

Query: 382  PSGPVASSGEFFGSASQPAVELVSGSQSALGPP-----PAASNSSDLFDLMGSSQATMTS 436
              G   ++     + S   VE  +   S+ G P     PA+S S     L G S A  T 
Sbjct: 3724 SPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSP---GLQGESTAFQTH 3780

Query: 437  SQS 439
              S
Sbjct: 3781 PAS 3783



 Score = 32.7 bits (73), Expect = 1.0
 Identities = 46/172 (26%), Positives = 73/172 (42%), Gaps = 19/172 (11%)

Query: 303 NASTHTPQSSVKTSVPSSKSSGDLVDLFDGTSQSTGGSADLFGGFADFGSAAASGSFPSQ 362
           N ST +  S +  S  ++   G+       TS ST  S+D F  F+D+G    S +F + 
Sbjct: 154 NHSTFSGFSQITGSTVNTSIGGNT------TSASTPSSSDPFTTFSDYG---VSVTFITG 204

Query: 363 VTATSGNGDFGDWSAFNQ----APSGPVASSGEFFGSASQPAVELVSGSQSALGPPPAAS 418
            TAT    D    S  ++    + SGP A+    F S S  +V +     S     P  S
Sbjct: 205 STATKHFLDSSTNSGHSEESTVSHSGPGATGTTLFPSHSATSVFVGEPKTS-----PITS 259

Query: 419 NSSDLFDLMGSSQATMTSSQSMNFSMMSTNTVGLGLPMSRSQNTDMVQKSVS 470
            S +   L GS+     S +S  F   S  +    L  +R+ ++ + +KS +
Sbjct: 260 ASMETTALPGSTTTAGLSEKSTTF-YSSPRSPDRTLSPARTTSSGVSEKSTT 310



 Score = 30.4 bits (67), Expect = 5.1
 Identities = 65/271 (23%), Positives = 98/271 (36%), Gaps = 32/271 (11%)

Query: 227  SPERCSDSD--EEKKARRGRSPKGEFKDEEETVTTKHIHITQATETTTTRHKRTANPSKT 284
            SP R + S   EE  A        +     E+ T         T  ++T H  ++ PS T
Sbjct: 4732 SPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTT 4791

Query: 285  IDLGAAAHYTGDKASPDQNASTHTPQSSVKTSVPSSKSSGDLVDLFDGTSQSTGGSADLF 344
              L      T   +SP   A+TH P+SS  TS  S +S+         +S  T G   L 
Sbjct: 4792 SAL--VEEPTSYHSSPGSIATTHFPESST-TSGRSEESTA------SHSSPDTNGITPLP 4842

Query: 345  GGFADFGSAAASGSFPSQVTATSGNGDFGDWSAFNQAPSGPVASSGEFFGSASQPAVELV 404
              F   G  A S +F          G      A      G  A S   + S+  P   L 
Sbjct: 4843 AHFTTSGRIAESTTF------YISPGSMETTLASTATTPGLSAKSTILYSSSRSPDQTLS 4896

Query: 405  SGSQSALGPPPAASNSSDLFDLMGSSQATMTSSQSMNFSMMSTNTVGLGLPMSRSQNTDM 464
              S +      ++S S +   L   +++T T++        ST T GL    S+   T  
Sbjct: 4897 PASMT------SSSISGEPTSLYSQAESTHTTA-----FPASTTTSGL----SQESTTFH 4941

Query: 465  VQKSVSKTLPSTWSDPSVNISLDNLLPGMQP 495
             +   ++T  S  S  + + + +   P  QP
Sbjct: 4942 SKPGSTETTLSPGSITTSSFAQEFTTPHSQP 4972



 Score = 30.0 bits (66), Expect = 6.7
 Identities = 42/213 (19%), Positives = 76/213 (35%), Gaps = 22/213 (10%)

Query: 278 TANPSKTIDLGAAAHYTGDKASPDQNASTHTPQSSVKTSVPSSKSSGDLVDLFDGTSQST 337
           TA P  T   G +   T   +SP    +TH P S   + V    ++         T+   
Sbjct: 621 TALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFP 680

Query: 338 GGSADLFGGFADFGSAAASGSFPSQVTATSGNGDFG----DWSAFNQAPSG------PVA 387
           G +     G +   +A+ S   P+  T + G+        +++ F+  P        P  
Sbjct: 681 GSTT--MPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDN 738

Query: 388 SSGEFFGSASQPAVELVSGSQSALGPPPAAS--NSSDLFDLMGSSQATMTSSQSMNFSMM 445
           ++      AS P         + L P  + +    S  F    SS+ T  +  +   + +
Sbjct: 739 TTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFV 798

Query: 446 STNTVGLGLPMS--------RSQNTDMVQKSVS 470
             +T   G P S        RS  + +V++S +
Sbjct: 799 EPSTTSHGSPSSIPTTHISARSTTSGLVEESTT 831



 Score = 30.0 bits (66), Expect = 6.7
 Identities = 50/243 (20%), Positives = 86/243 (35%), Gaps = 13/243 (5%)

Query: 220  RRKDREDSPERCSDSDEEKKARRGRSPKGEFKDE---EETVTTKHIHITQATETTTTRHK 276
            R  D   SP   + S   +++    S  G        + T T+       A+ ++    +
Sbjct: 3005 RSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTE 3064

Query: 277  RTANPSKTIDLGAAAHYTGDKASPDQNASTHTPQSS-----VKTSVPSSKSSGDLVDLFD 331
             T +P  T         T   +SP    +T  P  +     V+ S P+  S+G L     
Sbjct: 3065 ATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLT 3124

Query: 332  GTSQSTGGSADLFGGFADFGSAAASGSFPSQVTATSGNGDFGDWSAFNQAPSGPVASSGE 391
              S ++ G  +    F  + S++ +   P   TA          S  +  P+   ++S  
Sbjct: 3125 PASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASST 3184

Query: 392  FFGSASQPAVELVSGSQSALGPPPAASNSSDLFDLMGSSQATMTSSQSMNFSMM--STNT 449
              G + +     V  S  A G     + S+    L+G    +  SS S   + +  ST T
Sbjct: 3185 TLGRSEESTT--VHSSPGATGTALFPTRSATSV-LVGEPTTSPISSGSTETTALPGSTTT 3241

Query: 450  VGL 452
             GL
Sbjct: 3242 AGL 3244



 Score = 29.6 bits (65), Expect = 8.7
 Identities = 50/243 (20%), Positives = 86/243 (35%), Gaps = 13/243 (5%)

Query: 220  RRKDREDSPERCSDSDEEKKARRGRSPKGEFKDEEETVTTKHIHITQATETTTTRH---K 276
            R  D   SP   + S   +++    S  G         +T    ++Q   T+ +     +
Sbjct: 1448 RSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTE 1507

Query: 277  RTANPSKTIDLGAAAHYTGDKASPDQNASTHTPQSS-----VKTSVPSSKSSGDLVDLFD 331
             T +P  T         T   +SP    +T  P  +     V+ S P+  S+G L     
Sbjct: 1508 ATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLT 1567

Query: 332  GTSQSTGGSADLFGGFADFGSAAASGSFPSQVTATSGNGDFGDWSAFNQAPSGPVASSGE 391
              S ++ G  +    F  + S++ +   P   TA          S  +  P+   ++S  
Sbjct: 1568 PASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASST 1627

Query: 392  FFGSASQPAVELVSGSQSALGPPPAASNSSDLFDLMGSSQATMTSSQSMNFSMM--STNT 449
              G + +     V  S  A G     + S+    L+G    +  SS S   + +  ST T
Sbjct: 1628 TLGRSEESTT--VHSSPGATGTALFPTRSATSV-LVGEPTTSPISSGSTETTALPGSTTT 1684

Query: 450  VGL 452
             GL
Sbjct: 1685 AGL 1687



 Score = 29.6 bits (65), Expect = 8.7
 Identities = 63/326 (19%), Positives = 110/326 (33%), Gaps = 18/326 (5%)

Query: 220  RRKDREDSPERCSDSDEEKKARRGRSPKGEFKDEEETVTTKHIHITQATETTTTRH---K 276
            R  D   SP   + S   +++    S  G         +T    ++Q   T+ +     +
Sbjct: 4088 RSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTE 4147

Query: 277  RTANPSKTIDLGAAAHYTGDKASPDQNASTHTPQSS-----VKTSVPSSKSSGDLVDLFD 331
             T +P  T         T   +SP    +T  P  +     V+ S P+  S+G L     
Sbjct: 4148 ATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLT 4207

Query: 332  GTSQSTGGSADLFGGFADFGSAAASGSFPSQVTATSGNGDFGDWSAFNQAPSGPVASSGE 391
              S ++ G  +    F  + S++ +   P   TA          S  +  P+   ++S  
Sbjct: 4208 PASSTSTGLQEESTTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSASST 4267

Query: 392  FFGSASQPAVELVSGSQSALGPPPAASNSSDLFDLMGSSQATMTSSQSMNFSMM--STNT 449
              G + +     V  S  A G     + S+    L+G    +  SS S   + +  ST T
Sbjct: 4268 TLGRSEESTT--VHSSPGATGTALFPTRSATSV-LVGEPTTSPISSGSTETTALPGSTTT 4324

Query: 450  VGLGLPMSRSQNTDMVQKSVSKTLPSTWSDPSVNISLDNLLPGMQ-----PSKPQQPSLN 504
             GL    +   ++     +      +T S  S   +  +  PG       PS    P ++
Sbjct: 4325 AGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSMHTTAFPSSTTMPGVS 4384

Query: 505  TMIQQQNMQQPMNVMTQSFGAVNLSS 530
                  +        T S G+   SS
Sbjct: 4385 QESTASHSSPGSTDTTLSPGSTTASS 4410


>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
          Length = 2968

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 46/191 (24%), Positives = 73/191 (38%), Gaps = 23/191 (12%)

Query: 331  DGTSQSTGGSADLFGGFADFGSAAASGSFPSQVTATSGNGDFG------DWSAFNQAPSG 384
            DG  +S   S+   G  +   S+++SGS          NGD G      + SA +   + 
Sbjct: 2552 DGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAAS 2611

Query: 385  PVASSGEFFGSASQPAVELVSGSQSALGPPPAASNSSDLFDLMGSSQATMTSSQSMNFSM 444
            P +SS     S+S  +    S S S+     ++S+SS       SS ++ +SS S + S 
Sbjct: 2612 PASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2671

Query: 445  MSTN--------------TVGLGLPMSRSQNTDMVQKSVSKTLPSTWSDPSVNISLDNLL 490
             +                T G   P +++       K   K  PS  S      +     
Sbjct: 2672 TTDEDSSCSSDDEAAPAPTAG---PSAQAALPTKATKQAGKARPSAHSPGKKTPAPQPQA 2728

Query: 491  PGMQPSKPQQP 501
            P  QP++P QP
Sbjct: 2729 PPPQPTQPLQP 2739



 Score = 29.6 bits (65), Expect = 8.7
 Identities = 28/122 (22%), Positives = 54/122 (44%), Gaps = 13/122 (10%)

Query: 297  KASPDQNASTHTPQSSVKTSVPSSKSSGDLVDLFDGTSQSTGGSADLFGGFADFGSAAAS 356
            +A+   ++S+ +  SS  +S  SS SS         +S S+  S+      +   S+++S
Sbjct: 2608 RAASPASSSSSSSSSSSSSSSSSSSSS-------SSSSSSSSSSSSSSSSSSSSSSSSSS 2660

Query: 357  GSFPSQVTATSGNGDFGDWSAFNQAPSGPVASSGEFFGSASQPAVELVSGSQSALGPPPA 416
             S  S  +++S   +    S+ ++A   P A      G ++Q A+   +  Q+    P A
Sbjct: 2661 SSSSSSSSSSSTTDEDSSCSSDDEAAPAPTA------GPSAQAALPTKATKQAGKARPSA 2714

Query: 417  AS 418
             S
Sbjct: 2715 HS 2716


>gi|239754668 PREDICTED: mucin 12 [Homo sapiens]
          Length = 1952

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 59/251 (23%), Positives = 98/251 (39%), Gaps = 47/251 (18%)

Query: 268  TETTTTRHKR------TANPSKTIDLGAAAHYTGDKASPDQNASTHTPQSSVKTSV---- 317
            +E +TT H R      TA P  T   G +   T   +SP    +T +P+S+  +S+    
Sbjct: 1023 SEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPRSTTASSLGPES 1082

Query: 318  ---------------PSSKSSGDLVDLFDGTSQSTG---------GSADLFGGFADFGSA 353
                           P + ++  L++       STG         GS    G    F S 
Sbjct: 1083 TTFHSGPGSTETTLLPDNTTASGLLEASTPVHSSTGSPRTTLSPAGSTTRQGESTTFQSW 1142

Query: 354  AAS-GSFPSQVTATSGNGDFGDWS--AFNQAPSGPVASSGEFFGSASQPAVELVSGSQSA 410
             +S  + P+  T TS   +    S  + +  P+   ++S   FG + +      S    A
Sbjct: 1143 PSSKDTMPAPPTTTSAFVELSTTSHGSPSSIPTTHFSASSTTFGRSEESTTVHSSPVAPA 1202

Query: 411  LGPPPAASNSSDLFDLMGSSQATMTSSQSMNFSMMSTNTVGLGLPMSRSQNTDMVQKSVS 470
              P PA S +S L +   +  ++  S+Q+M+F   ST +        RS+ +     S +
Sbjct: 1203 TTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTAS-------GRSEESRTSHSSTT 1255

Query: 471  KTL---PSTWS 478
             T+   PST S
Sbjct: 1256 HTISSPPSTTS 1266



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 87/420 (20%), Positives = 147/420 (35%), Gaps = 49/420 (11%)

Query: 179 EPKSKWDEEWDKNKSAFPFSDKLGELSDKIGSTIDDTISKFRRKDREDSPERCSDSDEEK 238
           EPK+          +A P S     LS+K  +      S  R  DR  SP R + S   +
Sbjct: 172 EPKTSPITSASMETTALPGSTTTAGLSEKSTTFY----SSPRSPDRTLSPARTTSSGVSE 227

Query: 239 KARRGRSPKGEFKDEEETVTTKHIHITQATETTTTRHKRTANPSKTIDLGAAAHYTGDKA 298
           K+    S  G         +T    ++Q +   T  H    +   T+  G     T    
Sbjct: 228 KSTTSHSRPGPTHTIAFPDSTTMPGVSQES---TASHSIPGSTDTTLSPGTT---TPSSL 281

Query: 299 SPDQNASTHTPQSSVKTSVPSSKSSGDLVDLFDGTSQSTGG--------SADLFGG---- 346
            P+      +P  +  T +P + ++  L++       STG         S+    G    
Sbjct: 282 GPESTTFHSSPGYTKTTRLPDNTTTSGLLEASTPVHSSTGSPHTTLSPASSTTHEGEPTT 341

Query: 347 FADFGSAAASGSFPSQVTATSGNGDFGDWSAFNQAPSGPVASSGEFFGSASQPAVELVSG 406
           F  + S+  +   PS  T+          S+ +  P+   ++S    G + +      S 
Sbjct: 342 FQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPVHSSP 401

Query: 407 SQSALGPPPAASNSSDLFDLMGSSQATMTSSQSMNFSMMSTNTVGLGLPMSRSQNTDMVQ 466
             +A  PPPA S +S   +   +   +  S+Q+M+F   ST +         S+ +    
Sbjct: 402 VATATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPESSTTS-------GHSEESATFH 454

Query: 467 KSVSKTLPSTWSDPSVNISLDNLLPGMQPSKPQQPSLNTMIQQQNMQQPMNVMTQSFGAV 526
            S + T  ST   PS   +L               S ++ +         +  T S G  
Sbjct: 455 GSTTHTKSST---PSTTAAL------------AHTSYHSSLGSTETTHFRDSSTIS-GRS 498

Query: 527 NLSSPSNMLPVRPQTNALIGGPMPMSMPNVMTGTMGMAPLGNTPMMNQSMMGMNMNIGMS 586
             S  S+  P    T  L  G    S P+V+ G    +P+ +  M   ++ G     G+S
Sbjct: 499 EESKASHSSPDAMATTVLPAG----STPSVLVGDSTPSPISSGSMETTALPGSTTKPGLS 554



 Score = 34.7 bits (78), Expect = 0.27
 Identities = 69/332 (20%), Positives = 119/332 (35%), Gaps = 33/332 (9%)

Query: 256 TVTTKHIHITQATETTTTRHKRTANPSKTIDLGAAAHYTGDKASPDQNASTHTPQSSVKT 315
           + T  H   +    ++      T  P+++   G     T    SP    + H P+SS  T
Sbjct: 385 STTLGHSEESTPVHSSPVATATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPESST-T 443

Query: 316 SVPSSKSSGDLVDLFDGTSQSTGGSADLFGGFADFGSAAASGSFPSQVTATSGNGDFGDW 375
           S  S +S+      F G++  T  S           +A A  S+ S + +T     F D 
Sbjct: 444 SGHSEESA-----TFHGSTTHTKSSTP------STTAALAHTSYHSSLGSTETT-HFRDS 491

Query: 376 SAFN-------QAPSGPVASSGEFFGSASQPAVELVSGSQSALGPPPAASNSSDLFDLMG 428
           S  +        + S P A +     + S P+V LV  S     P P +S S +   L G
Sbjct: 492 STISGRSEESKASHSSPDAMATTVLPAGSTPSV-LVGDST----PSPISSGSMETTALPG 546

Query: 429 SSQATMTSSQSMNFSMMSTNTVGLGLPMSRSQNTDMVQKSVSKTLPSTWSDPSVNISLDN 488
           S+     S +S  F     +     LP S + +    + + S + P   S  +       
Sbjct: 547 STTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPG--STHTTAFPGST 604

Query: 489 LLPGMQPSKPQQ-----PSLNTMIQQQNMQQPMNVMTQSFGAVNLSSPSNMLPVRPQTNA 543
            +PG+            P+  T+         +     +F +   S+ + +LP     + 
Sbjct: 605 TMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASG 664

Query: 544 LIGGPMPMSMPNVMTGTMGMAPLGNTPMMNQS 575
           L+   MP+        T  ++P G+T    +S
Sbjct: 665 LLEASMPVHSSTRSPHTT-LSPAGSTTRQGES 695



 Score = 33.5 bits (75), Expect = 0.60
 Identities = 64/299 (21%), Positives = 104/299 (34%), Gaps = 32/299 (10%)

Query: 268  TETTTTRHKR------TANPSKTIDLGAAAHYTGDKASPDQNASTHTPQSSV------KT 315
            +E +TT H R      TA P  T   G + H T   +SP    +T  P S+        T
Sbjct: 912  SEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTXLVGEPT 971

Query: 316  SVPSSKSSGDLVDLFDGTSQSTGGSADLFGGFADFGSAAASGSFPSQVTATSGNGDFGDW 375
            + P S  S +   L   T+     +A L      F S+  S        +T+ +G   + 
Sbjct: 972  TSPISSGSTETTALPGSTT-----TAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEES 1026

Query: 376  SAFNQAPSGPVASSGEFFGSASQPAV--ELVSGSQSALGPPPAASNSSDLFDLMGSSQAT 433
            +  +  P     ++  F GS + P V  E  +   S        S  S     +G    T
Sbjct: 1027 TTSHSRPGSTHTTA--FPGSTTMPGVSQESTASHSSPGSTDTTLSPRSTTASSLGPESTT 1084

Query: 434  MTSSQ-SMNFSMMSTNTVGLGLPMSRS---QNTDMVQKSVSKTLPSTWSDPSVNISLDNL 489
              S   S   +++  NT   GL  + +    +T   + ++S    +T    S        
Sbjct: 1085 FHSGPGSTETTLLPDNTTASGLLEASTPVHSSTGSPRTTLSPAGSTTRQGESTTFQSWPS 1144

Query: 490  LPGMQPSKPQQPSLNTMIQQQNMQQPMNVMT-------QSFGAVNLSSPSNMLPVRPQT 541
                 P+ P   S    +   +   P ++ T        +FG    S+  +  PV P T
Sbjct: 1145 SKDTMPAPPTTTSAFVELSTTSHGSPSSIPTTHFSASSTTFGRSEESTTVHSSPVAPAT 1203



 Score = 32.7 bits (73), Expect = 1.0
 Identities = 46/172 (26%), Positives = 73/172 (42%), Gaps = 19/172 (11%)

Query: 303 NASTHTPQSSVKTSVPSSKSSGDLVDLFDGTSQSTGGSADLFGGFADFGSAAASGSFPSQ 362
           N ST +  S +  S  ++   G+       TS ST  S+D F  F+D+G    S +F + 
Sbjct: 75  NHSTFSGFSQITGSTVNTSIGGNT------TSASTPSSSDPFTTFSDYG---VSVTFITG 125

Query: 363 VTATSGNGDFGDWSAFNQ----APSGPVASSGEFFGSASQPAVELVSGSQSALGPPPAAS 418
            TAT    D    S  ++    + SGP A+    F S S  +V +     S     P  S
Sbjct: 126 STATKHFLDSSTNSGHSEESTVSHSGPGATGTTLFPSHSATSVFVGEPKTS-----PITS 180

Query: 419 NSSDLFDLMGSSQATMTSSQSMNFSMMSTNTVGLGLPMSRSQNTDMVQKSVS 470
            S +   L GS+     S +S  F   S  +    L  +R+ ++ + +KS +
Sbjct: 181 ASMETTALPGSTTTAGLSEKSTTF-YSSPRSPDRTLSPARTTSSGVSEKSTT 231



 Score = 30.4 bits (67), Expect = 5.1
 Identities = 65/271 (23%), Positives = 98/271 (36%), Gaps = 32/271 (11%)

Query: 227  SPERCSDSD--EEKKARRGRSPKGEFKDEEETVTTKHIHITQATETTTTRHKRTANPSKT 284
            SP R + S   EE  A        +     E+ T         T  ++T H  ++ PS T
Sbjct: 1206 SPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTT 1265

Query: 285  IDLGAAAHYTGDKASPDQNASTHTPQSSVKTSVPSSKSSGDLVDLFDGTSQSTGGSADLF 344
              L      T   +SP   A+TH P+SS  TS  S +S+         +S  T G   L 
Sbjct: 1266 SAL--VEEPTSYHSSPGSIATTHFPESST-TSGRSEESTA------SHSSPDTNGITPLP 1316

Query: 345  GGFADFGSAAASGSFPSQVTATSGNGDFGDWSAFNQAPSGPVASSGEFFGSASQPAVELV 404
              F   G  A S +F          G      A      G  A S   + S+  P   L 
Sbjct: 1317 AHFTTSGRIAESTTF------YISPGSMETTLASTATTPGLSAKSTILYSSSRSPDQTLS 1370

Query: 405  SGSQSALGPPPAASNSSDLFDLMGSSQATMTSSQSMNFSMMSTNTVGLGLPMSRSQNTDM 464
              S +      ++S S +   L   +++T T++        ST T GL    S+   T  
Sbjct: 1371 PASMT------SSSISGEPTSLYSQAESTHTTA-----FPASTTTSGL----SQESTTFH 1415

Query: 465  VQKSVSKTLPSTWSDPSVNISLDNLLPGMQP 495
             +   ++T  S  S  + + + +   P  QP
Sbjct: 1416 SKPGSTETTLSPGSITTSSFAQEFTTPHSQP 1446



 Score = 29.6 bits (65), Expect = 8.7
 Identities = 42/213 (19%), Positives = 75/213 (35%), Gaps = 22/213 (10%)

Query: 278 TANPSKTIDLGAAAHYTGDKASPDQNASTHTPQSSVKTSVPSSKSSGDLVDLFDGTSQST 337
           TA P  T   G +   T   +SP    +TH P S   + V    ++         T+   
Sbjct: 542 TALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFP 601

Query: 338 GGSADLFGGFADFGSAAASGSFPSQVTATSGNGDFG----DWSAFNQAPSG------PVA 387
           G +     G +   +A+ S   P+  T + G+        +++ F+  P        P  
Sbjct: 602 GSTT--MPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDN 659

Query: 388 SSGEFFGSASQPAVELVSGSQSALGPPPAAS--NSSDLFDLMGSSQATMTSSQSMNFSMM 445
           ++      AS P         + L P  + +    S  F    SS  T  +  +   + +
Sbjct: 660 TTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSNDTRPAPPTTTSAFV 719

Query: 446 STNTVGLGLPMS--------RSQNTDMVQKSVS 470
             +T   G P S        RS  + +V++S +
Sbjct: 720 EPSTTSHGSPSSIPTTHISARSTTSGLVEESTT 752


>gi|167736355 mucin 4 isoform a [Homo sapiens]
          Length = 5284

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 61/269 (22%), Positives = 100/269 (37%), Gaps = 25/269 (9%)

Query: 259 TKHIHITQATETTTTRHKRTANPSKTIDLGAAAHYTGDKASPDQNASTHTPQSSVKTSVP 318
           T+    T+ ++T+T  H+ T+ PS +  +         K SP    +T +  S   TS+ 
Sbjct: 200 TRSTQTTRESQTSTLTHRTTSTPSFSPSVHNVTGTVSQKTSPSGETATSSLCSVTNTSMM 259

Query: 319 SSKSSGDLVDLFDGTSQSTG-----GSADLFGGFADFGSAAASGSFP-SQVTATSGNGDF 372
           +S+     + +   T  + G      S  + G      SAA     P  Q  AT      
Sbjct: 260 TSEK----ITVTTSTGSTLGNPGETSSVPVTGSLMPVTSAALVTFDPEGQSPATFSRTST 315

Query: 373 GDWSAFN-----QAPSGPVASSGEFFGSASQPAVELVSGSQSALGPPPAASNSSDLFDLM 427
            D +AF+     Q+      S      + +      V  S S   P    S      +  
Sbjct: 316 QDTTAFSKNHQTQSVETTRVSQINTLNTLTPVTTSTVLSSPSGFNPSGTVSQ-----ETF 370

Query: 428 GSSQATMTSSQSMNFSMMSTNTVGLGLPMSRSQ---NTDMVQKSVSKTLPSTWSDPSVNI 484
            S + T +S  S++ + + T+ V   +P SR     NT+    SVS T+ +  S  S   
Sbjct: 371 PSGETTTSSPSSVSNTFLVTSKV-FRMPTSRDSTLGNTEETSLSVSGTISAITSKVSTIW 429

Query: 485 SLDNLLPGMQPSKPQQPSLNTMIQQQNMQ 513
             D L   + PS    P ++T    Q  +
Sbjct: 430 WSDTLSTALSPSS-LPPKISTAFHTQQSE 457



 Score = 38.9 bits (89), Expect = 0.014
 Identities = 65/271 (23%), Positives = 105/271 (38%), Gaps = 37/271 (13%)

Query: 301  DQNASTHTPQSSVKTSVPSSKSSGDLVDL--FDGTSQSTGGSADLFGGFADFGSAAASGS 358
            D ++++    +S+  ++PSS SSG    L   D +S STG +  L     D  S +   +
Sbjct: 1829 DASSASTGDTTSLPVTIPSSASSGHTTSLPVTDASSVSTGHATSLL--VTDASSVSTGDT 1886

Query: 359  FPSQVTATSGNGDFGDWSAFNQAPSGPVASSGEFFGSASQPAVELVSGSQSALGPPPAAS 418
             P  VT T+ +   GD +  +   +  V++      + S P   L S S     P P  S
Sbjct: 1887 TPLPVTDTN-SASTGDTTPLHVTDASSVSTG----HATSLPVTSLSSASTGDTTPLPVTS 1941

Query: 419  NSSDLFDLMGSSQATMTSSQSMNFSMMSTNTVGLGLPMSRSQNTDMVQKSVSKTLPSTWS 478
             SS       +S    T     + S + T      LP+     TD    S     P   +
Sbjct: 1942 PSS-------ASSGHTTPLPVTDASSVPTGH-ATSLPV-----TDASSVSTGHATPLPVT 1988

Query: 479  DPSVNISLDNLLPGMQPSKPQQPSLNTMIQQQNMQQPMNVMTQSFGAVNLSSPSNMLPVR 538
            D S ++S  +  P         P  +T         P+ V + S  +   ++P   LPV 
Sbjct: 1989 DAS-SVSTGHATP--------LPVTDTSSVSTGQATPLPVTSLSSASTGDTTP---LPVT 2036

Query: 539  PQTNALIGGPMPM---SMPNVMTGTMGMAPL 566
              ++A  G   P+   S+ +V TG     P+
Sbjct: 2037 DTSSASTGQDTPLPVTSLSSVSTGDTTPLPV 2067


>gi|24308215 retrotransposon gag domain containing 1 [Homo sapiens]
          Length = 1388

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 63/254 (24%), Positives = 94/254 (37%), Gaps = 19/254 (7%)

Query: 352 SAAASGSFPSQVTATSGNGDFGDWSAFN---QAPSGPVASSGEFFGSASQPAVELVSGSQ 408
           +A  SG  P+Q     G+G    WS  N   +  S P   +      ++ P   L SG+ 
Sbjct: 352 TALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMSNPPVRATASGVMSAPPVRALDSGAM 411

Query: 409 SA-LGPPPAASNSSDLFDLMGSSQATMTSSQSMNFS-MMSTNTVGLGLPMSRSQNTDMVQ 466
           S  L   PA+ N S L   + +S A  TS  ++  S +MST    +    SR  +  +  
Sbjct: 412 STPLMGAPASGNMSTLQKTVPASGAMTTSLMTVPSSGVMSTEQ--MSATASRVMSAQLTM 469

Query: 467 KSVSKTLPSTWSDPSVNISLDNLLPGMQPSKP--QQPSLNTMIQQQNMQQPMNVMTQSFG 524
              S  +P T S  +V           + S P  + P+   M  Q         M+    
Sbjct: 470 AKTSGAMP-TGSMKAVAKQYKRATASGKMSTPLRRAPTSGAMSTQPVTATASETMSMPQL 528

Query: 525 AVNLSSPSNMLPVRPQTNALIGGPMPMSMPNVMTGTMGMAPLGNTPMMNQSMMGMNMNIG 584
            V  S   +ML +R   +        MSMP + T   G+        M    M   +   
Sbjct: 529 TVPASGSMSMLQMRAPVSE------AMSMPQMRTMASGLTSAAQMKAMTSGAMSTPL--- 579

Query: 585 MSAAGMGLTGTMGM 598
           M+A   G T T+ M
Sbjct: 580 MTAQTSGSTSTLLM 593



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 77/368 (20%), Positives = 131/368 (35%), Gaps = 60/368 (16%)

Query: 268  TETTTTRHKRTANPSKTIDLGAAAHYTGDKASPDQNASTHTPQSSVKTSVPSSKSSGDLV 327
            +ET +T   RT++P +   L   A  +G+ + P   A    P S    +   S + G + 
Sbjct: 764  SETMSTPLMRTSDPGERPSLLTRASSSGEMSLPLMRA----PASGEIATPLRSPAYGAM- 818

Query: 328  DLFDGTSQSTGGSADLFGGFADFGSAAASGSFPSQVTATSGNGDFGDWSAFNQAPSGPVA 387
                   Q T  ++ +         A  SG+    +T ++ +G  G      +AP   V 
Sbjct: 819  ----SAPQMTATASGMMSSMPQV-KAPISGAMSMPLTRSTASG--GMSMPLMRAPDSRVT 871

Query: 388  SSGEFFGSASQPAVELV------SGSQSALGPPPAASNSSDLFDLMGSSQATMTSSQSMN 441
            S+ +   +AS     L        G  S L   PA+         M +     ++ ++++
Sbjct: 872  STSQMMPTASGDMCTLPVRAPASGGVSSPLVRAPASGT-------MSTPLRRPSACETVS 924

Query: 442  FSMMSTNTVGLGLPMSRSQNTDMVQKSVSKTLPSTWSDPSVNISLDNLLPGMQPSKPQQP 501
              +M  +  G    MS +Q T MV   +SK L    +  ++ + L + +   + S P   
Sbjct: 925  TELMRASASG---HMSTAQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMPLME 981

Query: 502  SLNTMIQQQNMQQPMNVMTQSFGAVNLSSPSNML--PVRPQTN---------ALIGGPMP 550
            ++ +           N  + S      +    M   P+R   +         A + G MP
Sbjct: 982  TMASGATSTLQTSVANSRSMSLSQTTYTVSGRMATAPIRASASGARSTSFMRASVSGSMP 1041

Query: 551  MSMPNVMTGTMGMAPLGNTPMMNQSMMGMNMNIGMSAAGMGLTGTMGMGMPNI-AMTSGT 609
            M +P       GM                    GMS   M  T + GM  P + A   GT
Sbjct: 1042 MPLPRATASGCGM--------------------GMSMPQMTATDSRGMSTPLMRASGPGT 1081

Query: 610  VQPKQDAF 617
            +   Q AF
Sbjct: 1082 MSTPQTAF 1089


>gi|5174545 myocyte enhancer factor 2D [Homo sapiens]
          Length = 521

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 84/340 (24%), Positives = 131/340 (38%), Gaps = 31/340 (9%)

Query: 223 DREDSPERCSDSDEEKKARRGRSPKGEFKDEEETVTTKHIHITQATETTTTRHKRTANPS 282
           D EDS E+ S   E+K  R      G F+    TV   +  +      +     + +NPS
Sbjct: 102 DGEDSLEQ-SPLLEDKYRRASEELDGLFRRYGSTVPAPNFAMPVTVPVSNQSSLQFSNPS 160

Query: 283 KTI---DLGAAAHYTGDKASPDQNASTHTPQSSVKTSVPSSKSSGDLVDLFDGTSQSTGG 339
            ++    L  ++       SP Q A     ++SV   +P   +S     +  G   S  G
Sbjct: 161 GSLVTPSLVTSSLTDPRLLSPQQPA---LQRNSVSPGLPQRPASAGA--MLGGDLNSANG 215

Query: 340 SADLFGGFADFGSAAASGSFPSQVTATSGNGDFGDWSAFNQAPSGPVASSGEFFGSASQP 399
           +     G     + A+ G  P      +GN      +    A S P  +     G+ S+ 
Sbjct: 216 ACPSPVGNGYVSARASPGLLP----VANGNS----LNKVIPAKSPPPPTHSTQLGAPSRK 267

Query: 400 AVELVSGSQSALGPPPAASNSSDLFDLMGSSQATMT-SSQSMNFSMMSTNTVGL---GLP 455
               V  SQ+  G     +   D  DL  + +  ++ S+ S+   ++S  T  L   GLP
Sbjct: 268 PDLRVITSQAGKGLMHHLTE--DHLDLNNAQRLGVSQSTHSLTTPVVSVATPSLLSQGLP 325

Query: 456 MSR---SQNTDMVQKSVSKTLPSTWSDPSVNISLDNLLPGMQPSKPQQPSLNTMIQQQ-- 510
            S    + NTD    S   +    +S P   +SL N+    QP +PQQP      QQQ  
Sbjct: 326 FSSMPTAYNTDYQLTSAELSSLPAFSSPG-GLSLGNVTAWQQPQQPQQPQQPQPPQQQPP 384

Query: 511 NMQQPMNVMTQSFGAVNLSSPSNMLPVRPQTNALIGGPMP 550
             QQP     Q          S+++PV   +N + G P+P
Sbjct: 385 QPQQPQPQQPQQ-PQQPPQQQSHLVPV-SLSNLIPGSPLP 422


>gi|33946327 nucleoporin 214kDa [Homo sapiens]
          Length = 2090

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 56/244 (22%), Positives = 92/244 (37%), Gaps = 24/244 (9%)

Query: 268  TETTTTRHKRTANPSKTIDLGAAAHYTGDKASPDQNASTHTPQSSVKTSVPSSKSSGDLV 327
            T  +TT  K    PSK  +L   +   G+               S K   P++K+S   +
Sbjct: 1301 TALSTTSSKLETPPSKLGELLFPSSLAGETLGSFSGLRVGQADDSTK---PTNKASSTSL 1357

Query: 328  DLFDGTSQSTGGSADLFGGFADFG---------SAAASGSFPSQVTATSGNGDFGDWSAF 378
                 T  S   S   F      G         SA  +   P   T+TS    FG     
Sbjct: 1358 TSTQPTKTSGVPSGFNFTAPPVLGKHTEPPVTSSATTTSVAPPAATSTSSTAVFGSLPVT 1417

Query: 379  NQAPSGPVASSGEFFGSASQPAVELVSGSQSALGPPPAASNSSDLFDLMGSSQATMTSSQ 438
            +   SG ++  G    SA + +    S   ++  PP A   ++       ++    TS  
Sbjct: 1418 SAGSSGVISFGGTSL-SAGKTSFSFGSQQTNSTVPPSAPPPTT-------AATPLPTSFP 1469

Query: 439  SMNFSMMSTNTVGLGLPMSRSQNTDMVQKSVSKTLPSTWSDPSVNISLDNLLPGMQPSK- 497
            +++F  + ++     LPMS  ++T   +++ S  LP    D  V+ S  +LL   Q ++ 
Sbjct: 1470 TLSFGSLLSSATTPSLPMSAGRST---EEATSSALPEKPGDSEVSASAASLLEEQQSAQL 1526

Query: 498  PQQP 501
            PQ P
Sbjct: 1527 PQAP 1530



 Score = 38.9 bits (89), Expect = 0.014
 Identities = 46/165 (27%), Positives = 67/165 (40%), Gaps = 25/165 (15%)

Query: 306  THTPQSSVKTSVPSSKSSGDLVDLFDGTSQSTGGSADLFGGFA----------DFGSAAA 355
            T T  SSV    P++ SS     L + T+ +   +  +FG  A            GS A+
Sbjct: 1637 TVTSGSSVFAQPPAASSSSAFNQLTNNTATAPSATP-VFGQVAASTAPSLFGQQTGSTAS 1695

Query: 356  ---------SGSFPSQVTATSGNGDFGDWSAFNQAPSGPVASSGEFFGSASQPAVELVSG 406
                     S  F S    T+  G FG  +    +  G  ASS     S SQP       
Sbjct: 1696 TAAATPQVSSSGFSSPAFGTTAPGVFGQTTFGQASVFGQSASSAASVFSFSQPGF----S 1751

Query: 407  SQSALGPPPAASNSSDLFDLMGSSQATMTSSQSMNFSMMSTNTVG 451
            S  A G P +++ +S    + G++ +T +SS S +F   S NT G
Sbjct: 1752 SVPAFGQPASSTPTSTSGSVFGAASST-SSSSSFSFGQSSPNTGG 1795



 Score = 33.9 bits (76), Expect = 0.46
 Identities = 39/164 (23%), Positives = 68/164 (41%), Gaps = 25/164 (15%)

Query: 304  ASTHTPQSSVKTSVPSSKSSGDLVDLFDGTSQSTGGSADLFGGFADFGSAAASGSFPSQV 363
            A+T T  ++V  S+P + +    V  F GTS S G ++  FG  +   ++    S P   
Sbjct: 1401 AATSTSSTAVFGSLPVTSAGSSGVISFGGTSLSAGKTSFSFG--SQQTNSTVPPSAPPPT 1458

Query: 364  TATSGNGDFGDWSAFNQAPSGPVASSGEFFGSASQPAVELVSGSQSALGPPPAASNSSDL 423
            TA           A     S P  S G    SA+ P++ + +G  +        + SS L
Sbjct: 1459 TA-----------ATPLPTSFPTLSFGSLLSSATTPSLPMSAGRST------EEATSSAL 1501

Query: 424  FDLMGSSQATMTSSQSMNFSMMSTNTVGLGLPMSRSQNTDMVQK 467
             +  G S+ + +++  +     +       LP +  Q +D V+K
Sbjct: 1502 PEKPGDSEVSASAASLLEEQQSAQ------LPQAPPQTSDSVKK 1539



 Score = 32.7 bits (73), Expect = 1.0
 Identities = 26/75 (34%), Positives = 32/75 (42%), Gaps = 15/75 (20%)

Query: 339  GSADLFGGFADFGSAAASGSFPS--------------QVTATSGNGDFGDWSAFNQAPSG 384
            GS   FGG   FG   A GS P+              + TA +  G FG  S+ N    G
Sbjct: 1977 GSPPTFGGSPGFGGVPAFGSAPAFTSPLGSTGGKVFGEGTAAASAGGFGFGSSSNTTSFG 2036

Query: 385  PVAS-SGEFFGSASQ 398
             +AS +   FGS SQ
Sbjct: 2037 TLASQNAPTFGSLSQ 2051



 Score = 32.0 bits (71), Expect = 1.8
 Identities = 74/336 (22%), Positives = 122/336 (36%), Gaps = 35/336 (10%)

Query: 297  KASPDQNASTHTPQSSVKTSVPSSKSSGDLVDLFDGTSQSTGGSADLFGGFADFGSAAAS 356
            +A P  + S        + +V +S ++     L   ++++T  +  +     +    A+S
Sbjct: 1528 QAPPQTSDSVKKEPVLAQPAVSNSGTAASSTSLVALSAEATPATTGVPDARTEAVPPASS 1587

Query: 357  GSFPSQVTATSGNGDFGDWSAFNQAPSGPVASSGEFF----GSASQPAVELVSGSQSALG 412
             S P Q   T+         A  +  S P+ASS         SA   A   V+   S   
Sbjct: 1588 FSVPGQTAVTAAAISSAGPVAV-ETSSTPIASSTTSIVAPGPSAEAAAFGTVTSGSSVFA 1646

Query: 413  PPPAASNSSDLFDLMGSSQATMTSSQSMNFSMMSTNTVGLGLPMSRSQNTDMVQKSVSKT 472
             PPAAS+SS  F+ + ++ AT  S+  + F  ++ +T     P    Q T     + + T
Sbjct: 1647 QPPAASSSS-AFNQLTNNTATAPSATPV-FGQVAASTA----PSLFGQQTGSTASTAAAT 1700

Query: 473  LPSTWSDPSVNISLDNLLPGM--QPSKPQQ----PSLNTMIQQQNMQQPMNVMTQSFGAV 526
             P   S    + +     PG+  Q +  Q      S ++     +  QP      +FG  
Sbjct: 1701 -PQVSSSGFSSPAFGTTAPGVFGQTTFGQASVFGQSASSAASVFSFSQPGFSSVPAFGQP 1759

Query: 527  NLSSPS----NMLPVRPQTNALIGGPMPMSMPNVMTGTMGMAPLGNTPMMNQSM---MGM 579
              S+P+    ++      T++        S PN   G  G +   N P   QS     G 
Sbjct: 1760 ASSTPTSTSGSVFGAASSTSSSSSFSFGQSSPNTGGGLFGQS---NAPAFGQSPGFGQGG 1816

Query: 580  NMNIGMSAA-------GMGLTGTMGMGMPNIAMTSG 608
            ++  G SAA       G       G G  N     G
Sbjct: 1817 SVFGGTSAATTTAATSGFSFCQASGFGSSNTGSVFG 1852



 Score = 30.4 bits (67), Expect = 5.1
 Identities = 17/46 (36%), Positives = 20/46 (43%), Gaps = 3/46 (6%)

Query: 330  FDGTSQSTGGSADLFGGFADFGSAAASGSFPSQVTATSGNGDFGDW 375
            F   SQ T G      GF+ FGS     SF S  ++  G   FG W
Sbjct: 2046 FGSLSQQTSGFGTQSSGFSGFGSGTGGFSFGSNNSSVQG---FGGW 2088


>gi|221219020 NYD-SP11 protein [Homo sapiens]
          Length = 2873

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 46/223 (20%), Positives = 93/223 (41%), Gaps = 20/223 (8%)

Query: 66   SRMLKDNKKNWRRVYKSLLLLAYLIRNGSERVVTSAREHIYDLRSLENYH--FVDEHGKD 123
            S + KD KK  R+  K        + N   R++    +   +   L   H   + +  ++
Sbjct: 2130 SELTKDEKKLARKQRK--------LANKMRRMINKEEKMTEEESKLARKHSEVILDDEEE 2181

Query: 124  QGINIRQKVKELVEFAQDDDRLREERKKAKKNKDKYVGVSSDSVGGFRYSERYDPEPKSK 183
             GI    + +E++ F +   R R+E K+  K K+K+    S  V      E +  E +S 
Sbjct: 2182 GGI----EEEEVIPFLKRRWRKRKEAKRGDKPKEKF----SSQVDEVESEEHFSEEMESL 2233

Query: 184  WDEEWDKNKSAFPFSDKLGELSDKIGSTIDDTISKFRRKDREDSPERCSDSDEEKKARRG 243
             DE   +   +    ++  E  ++    + +   +  RK+ E+  E+  + +EE+K ++ 
Sbjct: 2234 LDELEKQESLSSEEEEEREEEEEREEEEVRE--EEEERKEEEEGEEKQVEKEEEEKKKKK 2291

Query: 244  RSPKGEFKDEEETVTTKHIHITQATETTTTRHKRTANPSKTID 286
            +  K E   E+E V  +   I    ET +   +     S +++
Sbjct: 2292 KEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLE 2334



 Score = 32.0 bits (71), Expect = 1.8
 Identities = 32/146 (21%), Positives = 67/146 (45%), Gaps = 17/146 (11%)

Query: 110  SLENYHFVDEHGKDQGINIRQKVKELVEFAQDDDRLREERKKAKKNKDKYVGVSSDSVGG 169
            S E    +DE  K + ++  ++ +   E  ++++ +REE ++ K+ ++          G 
Sbjct: 2227 SEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEE----------GE 2276

Query: 170  FRYSERYDPEPKSKWDEEWDKNKSAFPFSDKLGELSDKIGSTIDDTISKFRRKDREDSPE 229
             +  E+ + E K K  E   K K      +++ E  ++I S  ++T S     D E+  E
Sbjct: 2277 EKQVEKEEEEKKKKKKE---KKKEEVQEKEEVFEEKEEIMSE-EETESL---SDEEEEEE 2329

Query: 230  RCSDSDEEKKARRGRSPKGEFKDEEE 255
             CS  +E  + +     + +FK +E+
Sbjct: 2330 SCSLEEEVDREKEILKKEKQFKLQEQ 2355


>gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo
            sapiens]
          Length = 2036

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 67/315 (21%), Positives = 116/315 (36%), Gaps = 32/315 (10%)

Query: 179  EPKSKWDEEWDKNKSAFPFSDKLGELSDKIGSTIDDTISKFRRKDREDSPERCSDSDEEK 238
            EP +          +A P S     LS+K  +      S  R  D   SP   + S   +
Sbjct: 1149 EPTTSPISSGSTETTALPGSTTTAGLSEKSTTFY----SSPRSPDTTLSPASTTSSGVSE 1204

Query: 239  KARRGRSPKGEFKDEEETVTTKHIHITQATETTTTRHKRTANPSKTIDLGAAAHYTGDKA 298
            ++    S  G       T       +   ++ +T  H    +   T+  G+    T    
Sbjct: 1205 ESTTSHSRPGS---THTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGST---TASSL 1258

Query: 299  SPDQNASTHTPQSSVKTSVPSSKSSGDLVDLFDGTSQSTG---------GSADLFGGFAD 349
             P+      +P S+  T +P + ++  L++       STG         GS    G    
Sbjct: 1259 GPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTT 1318

Query: 350  FGSAAAS-GSFPSQVTATSGNGDFGDWS--AFNQAPSGPVASSGEFFGSASQPAVELVSG 406
            F S  +S  + P+  T TS   +    S  + +  P+   ++S    G + +      S 
Sbjct: 1319 FQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSP 1378

Query: 407  SQSALGPPPAASNSSDLFDLMGSSQATMTSSQSMNFSMMSTNTVGLGLPMSRSQNTDMVQ 466
              +A  P PA S +S L +   +  ++  S+Q+M+F   ST +        RS+ +    
Sbjct: 1379 VATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTAS-------GRSEESRTSH 1431

Query: 467  KSVSKTL---PSTWS 478
             S + T+   PST S
Sbjct: 1432 SSTTHTISSPPSTTS 1446



 Score = 38.5 bits (88), Expect = 0.019
 Identities = 69/352 (19%), Positives = 125/352 (35%), Gaps = 39/352 (11%)

Query: 254 EETVTTKHIHITQATETTTTRHKRTANPSKTIDLGAAAHYTGDKASPDQNASTHTPQSSV 313
           + T ++  +  +    ++T   + T +P+ +   G     T  +  P    +T +P S+ 
Sbjct: 582 DSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTA 641

Query: 314 KTSVPSS----KSSGDLVDLFDGTSQSTGGSADLFGGFADFGSAAASGSFPSQV-TATSG 368
              V  S    +S G         S +T G ++    F    S  ASG+ PS   + TSG
Sbjct: 642 TAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIF--HSSPDASGTTPSSAHSTTSG 699

Query: 369 NGDF-------GDWSAFNQAPS----GPVASSGEFFGSASQPAVELVSGSQSALGPPPAA 417
            G+        G         S    G   +S  F+ S   P   L   S ++LG    +
Sbjct: 700 RGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEES 759

Query: 418 SNSSDLFDLMGSSQATMTSSQSMNFSMMSTNTVGLGLPMSRSQNT---DMVQKSVSKTLP 474
           + S       GS+ +T++ + +    +   +T         ++ T        SV    P
Sbjct: 760 TTSRSQ---PGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEP 816

Query: 475 STW-----SDPSVNISLDNLLPGMQPSKPQQPSLNTMIQQQNMQQPMNVMTQSFGAVNLS 529
           +T+     S  +   + D+   G+       P      Q      P  + T   G  + +
Sbjct: 817 TTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTG---LPATLTTADLGEESTT 873

Query: 530 SPSN-------MLPVRPQTNALIGGPMPMSMPNVMTGTMGMAPLGNTPMMNQ 574
            PS+       + P R  T+ L+G   P  +    T T  +     TP +++
Sbjct: 874 FPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSE 925



 Score = 36.6 bits (83), Expect = 0.071
 Identities = 48/178 (26%), Positives = 67/178 (37%), Gaps = 25/178 (14%)

Query: 269 ETTTTRHK-----RTANPSKTIDLGAAAHYTGDKASPDQNASTHTPQSSVKTSVPSSKSS 323
           E+TT+R +      TA P  T   G + H T   +SP    +T  P +S  TS PS +S+
Sbjct: 480 ESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLP-ASTTTSGPSQEST 538

Query: 324 GDLVDLFDGTSQSTGGSADLFGGFADFGSAAASGSFPSQVTATSGNGDFGDWSAF--NQA 381
                    TS S+ GS D     A    +  + SF  + T    N      + F  +  
Sbjct: 539 ---------TSHSSSGSTDT----ALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTT 585

Query: 382 PSGPVASSGEFFGSASQPAVELVSGSQSALGPPPAASNSSDLFDLMGSSQATMTSSQS 439
            SG V +S     S   P   L   S ++    P     S  F    +S  T  S  S
Sbjct: 586 SSGIVEASTRVHSSTGSPRTTLSPASSTS----PGLQGESTAFQTHPASTHTTPSPPS 639



 Score = 33.1 bits (74), Expect = 0.79
 Identities = 71/323 (21%), Positives = 116/323 (35%), Gaps = 28/323 (8%)

Query: 232 SDSDEEKKARRGRSPKGEFKDEEETVTTKHIHITQATETTTTRHKRTANPSKTIDLGAAA 291
           S   EE     G +   +      T    H     +  +T T H R    S TI  G + 
Sbjct: 10  SGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRD---SSTIS-GRSE 65

Query: 292 HYTGDKASPDQNAST-----HTPQSSVKTSVPSSKSSGDLVDLFDGTSQSTGGSADLFGG 346
                 +SPD  A+T      TP   V  S PS  SSG +       S +  G ++    
Sbjct: 66  ESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPGLSEKSTT 125

Query: 347 FADFGSAAASGSFPSQVTATSGNGDFGDWSAFNQAPSGPVASSGEFFGSASQPAVELVS- 405
           F     +  +   P+ +T++       + S  + +  G   ++  F GS + P +   S 
Sbjct: 126 FYSSPRSPDTTHLPASMTSSG----VSEESTTSHSRPGSTHTTA-FPGSTTMPGLSQEST 180

Query: 406 GSQSALGPPPAA-SNSSDLFDLMGSSQATMTSSQ-SMNFSMMSTNTVGLGLPMSRSQNTD 463
            S S+ GP     S  S     +G    T  S   S   +++  NT   GL +  S    
Sbjct: 181 ASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGL-LEASMPVH 239

Query: 464 MVQKSVSKTLPSTWSDPSVNISLD-NLLPGMQPSKPQQPSLNTMIQQQNMQQPMNVMTQS 522
              +S   TL    S      S   +  P  + ++P  P+  +   + +        T S
Sbjct: 240 SSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPS--------TTS 291

Query: 523 FGAVNLSSPSNMLPVRPQTNALI 545
            G+ + S P+  +  R  T+ L+
Sbjct: 292 HGSPS-SIPTTHISARSTTSGLV 313



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 57/228 (25%), Positives = 85/228 (37%), Gaps = 23/228 (10%)

Query: 227  SPERCSDSD--EEKKARRGRSPKGEFKDEEETVTTKHIHITQATETTTTRHKRTANPSKT 284
            SP R + S   EE  A        +     E+ T         T  ++T H  ++ PS T
Sbjct: 1386 SPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTT 1445

Query: 285  IDLGAAAHYTGDKASPDQNASTHTPQSSVKTSVPSSKSSGDLVDLFDGTSQSTGGSADLF 344
              L      T   +SP   A+TH P+SS  TS  S +S+         +S  T G   L 
Sbjct: 1446 SAL--VEEPTSYHSSPGSIATTHFPESST-TSGRSEESTA------SHSSPDTNGITPLP 1496

Query: 345  GGFADFGSAAASGSFPSQVTATSGNGDFGDWSAFNQAPSGPVASSGEFFGS--ASQPAVE 402
              F   G  A S +F          G      A      G  A S   + S    +P   
Sbjct: 1497 AHFTTSGRIAESTTF------YISPGSMETTLASTATTPGLSAKSTILYTSDLVGEPTTF 1550

Query: 403  LVSGSQSALGPPPAASNSSDLFDLMGSSQATMTSSQSMNFSMMSTNTV 450
             +S S +     PA+S++S L +       T  +S S   +++ST ++
Sbjct: 1551 YISPSPTYTTLFPASSSTSGLTE----ESTTFHTSPSFTSTIVSTESL 1594



 Score = 29.6 bits (65), Expect = 8.7
 Identities = 50/243 (20%), Positives = 86/243 (35%), Gaps = 13/243 (5%)

Query: 220  RRKDREDSPERCSDSDEEKKARRGRSPKGEFKDEEETVTTKHIHITQATETTTTRH---K 276
            R  D   SP   + S   +++    S  G         +T    ++Q   T+ +     +
Sbjct: 935  RSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTE 994

Query: 277  RTANPSKTIDLGAAAHYTGDKASPDQNASTHTPQSS-----VKTSVPSSKSSGDLVDLFD 331
             T +P  T         T   +SP    +T  P  +     V+ S P+  S+G L     
Sbjct: 995  ATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLT 1054

Query: 332  GTSQSTGGSADLFGGFADFGSAAASGSFPSQVTATSGNGDFGDWSAFNQAPSGPVASSGE 391
              S ++ G  +    F  + S++ +   P   TA          S  +  P+   ++S  
Sbjct: 1055 PASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASST 1114

Query: 392  FFGSASQPAVELVSGSQSALGPPPAASNSSDLFDLMGSSQATMTSSQSMNFSMM--STNT 449
              G + +     V  S  A G     + S+    L+G    +  SS S   + +  ST T
Sbjct: 1115 TLGRSEESTT--VHSSPGATGTALFPTRSATSV-LVGEPTTSPISSGSTETTALPGSTTT 1171

Query: 450  VGL 452
             GL
Sbjct: 1172 AGL 1174


>gi|91984781 ArfGAP with FG repeats 2 [Homo sapiens]
          Length = 481

 Score = 40.8 bits (94), Expect = 0.004
 Identities = 66/283 (23%), Positives = 95/283 (33%), Gaps = 48/283 (16%)

Query: 309 PQSSVKTSVPSSKSSGDLVDLFDGTSQSTGGSADLFGGFADFGSAAASGSFPSQVTATSG 368
           P SSVK      K+S DL+    G   +    A  F  F  FG     G  PSQ      
Sbjct: 214 PHSSVK------KASTDLLADIGGDPFAAPQMAPAFAAFPAFG-----GQTPSQ------ 256

Query: 369 NGDFGDWSAFNQAPSGPVASSGEFFGSASQPAVELVSGSQSALGPPPAASNSSDLFDLMG 428
            G F ++ AF+  PS  V  S    G AS  A            P PA S+    F    
Sbjct: 257 -GGFANFDAFSSGPSSSVFGSLPPAGQASFQA-----------QPTPAGSSQGTPFGATP 304

Query: 429 SSQATMTSSQSMNFSMMSTNTVGLGLPMSRSQNTDMVQKSVSKTLP-----------STW 477
            + A+  +S +   S +       G+P S       V    S T+              +
Sbjct: 305 LAPASQPNSLADVGSFLGPGVPAAGVPSSLFGMAGQVPPLQSVTMGGGGGSSTGLAFGAF 364

Query: 478 SDPSVNISLDNLLPGMQPSKPQQPSLNTMIQQQNMQQPMNVMTQSFGAVNLSSPSNMLPV 537
           ++P    +  + LP   P +P   +        +            GA   S P+ + P 
Sbjct: 365 TNPFTAPAAQSPLPSTNPFQPNGLAPGPGFGMSSAGPGFPQAVPPTGAFASSFPAPLFP- 423

Query: 538 RPQTNALIGGPMPMSMPNVMTGTMGMAPLGNTPMMNQSMMGMN 580
            PQT      P+         G +G A LG  P+   + +  N
Sbjct: 424 -PQT------PLVQQQNGSSFGDLGSAKLGQRPLSQPAGISTN 459


>gi|7657387 CCR4-NOT transcription complex, subunit 3 [Homo sapiens]
          Length = 753

 Score = 40.8 bits (94), Expect = 0.004
 Identities = 47/205 (22%), Positives = 74/205 (36%), Gaps = 21/205 (10%)

Query: 227 SPERCSDSDEEKKARRGRSPKGEFKDEEETVTTKHIHITQATETTTTRHKRTANPSKTID 286
           SP  C+  + E   +RGRS   E         +K +H  Q  ++        + P     
Sbjct: 273 SPANCTTENSEDDKKRGRSTDSEVSQSPAKNGSKPVHSNQHPQSPAVPPTYPSGPPPAAS 332

Query: 287 L-------------GAAAHYTGDKASPDQNASTHTPQSSVKTSVPSSKSSGDLVDLFDGT 333
                          A     G KASP  + ++ TP    +   P + S          +
Sbjct: 333 ALSTTPGNNGVPAPAAPPSALGPKASPAPSHNSGTPAPYAQAVAPPAPSGPSTTQPRPPS 392

Query: 334 SQSTGGSADLFGGFADFGSAAASGSFPSQVTATSGNGDFGDWSAFNQAPSGPVASSGEFF 393
            Q +GG     GG +  G +++S +  +   A   NG     S    +P+  VA S    
Sbjct: 393 VQPSGGG----GGGSGGGGSSSSSNSSAGGGAGKQNGATSYSSVVADSPA-EVALSSSGG 447

Query: 394 GSASQPAVELVSGSQSALGPPPAAS 418
            +AS  A+   SG  +   PPP+ S
Sbjct: 448 NNASSQALGPPSGPHN---PPPSTS 469


>gi|7661950 SH2 domain binding protein 1 [Homo sapiens]
          Length = 1173

 Score = 40.4 bits (93), Expect = 0.005
 Identities = 61/227 (26%), Positives = 99/227 (43%), Gaps = 41/227 (18%)

Query: 60  LMNMLWSRMLKDNKKNWRRVYKSLLLL-------AYLIRNGSER------VVTSAREHIY 106
           ++  L + +LKD K N + V  ++  L       +YL + G +         T AR+   
Sbjct: 760 VLQRLATSVLKDEKSNLKEVLNAVKELELAHRYFSYLSKVGDKMRFDLALAATEARQ-CS 818

Query: 107 DLRSLENYHFVDEHGKDQGIN-IRQKVKELVEFA-------QDDDRLRE--ERKKAKKNK 156
           DL S   YH      +D+    +R K ++  E         Q++ RLRE  E+KK  + +
Sbjct: 819 DLLSQAQYHVARARKQDEEERELRAKQEQEKELLRQKLLKEQEEKRLREKEEQKKLLEQR 878

Query: 157 DKYVGVSSDSVGGFRYSERYDPEPKSKWDEEWDKNKSAFPFSDKLGELSDKIGSTIDDT- 215
            +YV  + + +        +  E ++   +E  +       S K GE  + +    DD  
Sbjct: 879 AQYVEKTKNIL-------MFTGETEAT--KEKKRGGGGGRRSKKGGEFDEFVNDDTDDDL 929

Query: 216 -ISKFRRKDREDSPERCSDSDEE----KKARRGRSPKG-EFKDEEET 256
            ISK ++K R+ S       DEE    KK +R R PKG E  D++ET
Sbjct: 930 PISK-KKKRRKGSGSEQEGEDEEGGERKKKKRRRHPKGEEGSDDDET 975


>gi|16753205 ubiquilin 1 isoform 2 [Homo sapiens]
          Length = 561

 Score = 40.0 bits (92), Expect = 0.006
 Identities = 64/241 (26%), Positives = 97/241 (40%), Gaps = 36/241 (14%)

Query: 386 VASSGEFFGSASQPAVELVSGSQSALGPPPAASNSSDLFDLMGSSQATMTSSQSMNFSMM 445
           ++++ E FG    P   LVS + S  G  P+ + + D      + Q    +SQS + S  
Sbjct: 284 LSAAQEQFGG--NPFASLVSNTSSGEGSQPSRTENRDPLPNPWAPQ----TSQSSSASSG 337

Query: 446 STNTVGLGLPMSRSQNTDMVQKSVSKTLPSTWSDPSVNISLDNLLPGMQPSKPQQPSLNT 505
           + +TVG G   S +  T       S T P+    P V  S+ N  PGMQ S  QQ + N 
Sbjct: 338 TASTVG-GTTGSTASGT----SGQSTTAPNL--VPGVGASMFN-TPGMQ-SLLQQITENP 388

Query: 506 MIQQQNMQQP-MNVMTQSFGAVNLSSPSNMLPVRPQTNALIGGPMPM--------SMPNV 556
            + Q  +  P M  M QS  + N    + M    P T + +  P  M         +  +
Sbjct: 389 QLMQNMLSAPYMRSMMQSL-SQNPDLAAQM--QNPDTLSAMSNPRAMQALLQIQQGLQTL 445

Query: 557 MTGTMGMAPLGNTPMMNQSMMGMNMNIGMSAAGMGLTGTMGMGMPNIAMTSGTVQPKQDA 616
            T   G+ P G TP +          +G +    G  G+      N + T+GT +P    
Sbjct: 446 ATEAPGLIP-GFTPGLGA--------LGSTGGSSGTNGSNATPSENTSPTAGTTEPGHQQ 496

Query: 617 F 617
           F
Sbjct: 497 F 497


>gi|239749217 PREDICTED: similar to Mucin-12, partial [Homo sapiens]
          Length = 861

 Score = 39.7 bits (91), Expect = 0.008
 Identities = 87/420 (20%), Positives = 147/420 (35%), Gaps = 49/420 (11%)

Query: 179 EPKSKWDEEWDKNKSAFPFSDKLGELSDKIGSTIDDTISKFRRKDREDSPERCSDSDEEK 238
           EPK+          +A P S     LS+K  +      S  R  DR  SP R + S   +
Sbjct: 107 EPKTSPITSASMETTALPGSTTTAGLSEKSTTFY----SSPRSPDRTLSPARTTSSGVSE 162

Query: 239 KARRGRSPKGEFKDEEETVTTKHIHITQATETTTTRHKRTANPSKTIDLGAAAHYTGDKA 298
           K+    S  G         +T    ++Q +   T  H    +   T+  G     T    
Sbjct: 163 KSTTSHSRPGPTHTIAFPDSTTMPGVSQES---TASHSIPGSTDTTLSPGTT---TPSSL 216

Query: 299 SPDQNASTHTPQSSVKTSVPSSKSSGDLVDLFDGTSQSTGG--------SADLFGG---- 346
            P+      +P  +  T +P + ++  L++       STG         S+    G    
Sbjct: 217 GPESTTFHSSPGYTKTTRLPDNTTTSGLLEASTPVHSSTGSPHTTLSPSSSTTHEGEPTT 276

Query: 347 FADFGSAAASGSFPSQVTATSGNGDFGDWSAFNQAPSGPVASSGEFFGSASQPAVELVSG 406
           F  + S+  +   PS  T+          S+ +  P+   ++S    G + +      S 
Sbjct: 277 FQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPVHSSP 336

Query: 407 SQSALGPPPAASNSSDLFDLMGSSQATMTSSQSMNFSMMSTNTVGLGLPMSRSQNTDMVQ 466
             +A  PPPA S +S   +   +   +  S+Q+M+F   ST +         S+ +    
Sbjct: 337 VATATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPESSTTS-------GHSEESATFH 389

Query: 467 KSVSKTLPSTWSDPSVNISLDNLLPGMQPSKPQQPSLNTMIQQQNMQQPMNVMTQSFGAV 526
            S + T  ST   PS   +L               S ++ +         +  T S G  
Sbjct: 390 GSTTHTKSST---PSTTAAL------------AHTSYHSSLGSTETTHFRDSSTIS-GRS 433

Query: 527 NLSSPSNMLPVRPQTNALIGGPMPMSMPNVMTGTMGMAPLGNTPMMNQSMMGMNMNIGMS 586
             S  S+  P    T  L  G    S P+V+ G    +P+ +  M   ++ G     G+S
Sbjct: 434 EESKASHSSPDAMATTVLPAG----STPSVLVGDSTPSPISSGSMETTALPGSTTKPGLS 489



 Score = 31.6 bits (70), Expect = 2.3
 Identities = 40/142 (28%), Positives = 62/142 (43%), Gaps = 13/142 (9%)

Query: 333 TSQSTGGSADLFGGFADFGSAAASGSFPSQVTATSGNGDFGDWSAFNQ----APSGPVAS 388
           TS ST  S+D F  F+D+G    S +F +  TAT    D    S  ++    + SGP A+
Sbjct: 34  TSASTPSSSDPFTTFSDYG---VSVTFITGSTATKHFLDSSTNSGHSEESTVSHSGPGAT 90

Query: 389 SGEFFGSASQPAVELVSGSQSALGPPPAASNSSDLFDLMGSSQATMTSSQSMNFSMMSTN 448
               F S S  +V +     S     P  S S +   L GS+     S +S  F   S  
Sbjct: 91  GTTLFPSHSATSVFVGEPKTS-----PITSASMETTALPGSTTTAGLSEKSTTF-YSSPR 144

Query: 449 TVGLGLPMSRSQNTDMVQKSVS 470
           +    L  +R+ ++ + +KS +
Sbjct: 145 SPDRTLSPARTTSSGVSEKSTT 166


>gi|67782356 corneodesmosin precursor [Homo sapiens]
          Length = 529

 Score = 39.7 bits (91), Expect = 0.008
 Identities = 35/144 (24%), Positives = 61/144 (42%), Gaps = 3/144 (2%)

Query: 305 STHTPQSSVKTSVPSSKSSGD-LVDLFDGTSQSTGGSADLFGGFADFGSAAASGSFPSQV 363
           S+++  SS  +S+ S++SSG        G+S + GGSA  F     +   + S    S +
Sbjct: 66  SSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSYSSGSGSSL 125

Query: 364 TATSGNGDFGDWSAFNQAPSGPVASSGEFFGSASQPAVELVSGSQSALGPPPAASNSSDL 423
              SG+   G  S+ + +      SS     S+S  + +  S S          +N +  
Sbjct: 126 QGASGSSQLGSSSSHSGSSGSHSGSSSSH--SSSSSSFQFSSSSFQVGNGSALPTNDNSY 183

Query: 424 FDLMGSSQATMTSSQSMNFSMMST 447
             ++  SQ   +SS S  F + S+
Sbjct: 184 RGILNPSQPGQSSSSSQTFGVSSS 207


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.125    0.358 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,933,603
Number of Sequences: 37866
Number of extensions: 1144856
Number of successful extensions: 5308
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 327
Number of HSP's that attempted gapping in prelim test: 4672
Number of HSP's gapped (non-prelim): 841
length of query: 625
length of database: 18,247,518
effective HSP length: 108
effective length of query: 517
effective length of database: 14,157,990
effective search space: 7319680830
effective search space used: 7319680830
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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