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Search of human proteins with 7657550
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7657550 sentrin/SUMO-specific protease 1 [Homo sapiens]
(643 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7657550 sentrin/SUMO-specific protease 1 [Homo sapiens] 1299 0.0
gi|54607091 SUMO1/sentrin/SMT3 specific protease 2 [Homo sapiens] 294 1e-79
gi|21361499 SUMO1/sentrin/SMT3 specific protease 3 [Homo sapiens] 170 4e-42
gi|159032029 SUMO1/sentrin specific peptidase 5 [Homo sapiens] 159 8e-39
gi|156105703 SUMO1/sentrin specific peptidase 6 isoform 2 [Homo ... 71 4e-12
gi|156105701 SUMO1/sentrin specific peptidase 6 isoform 1 [Homo ... 71 4e-12
gi|116174736 sentrin/SUMO-specific protease 7 isoform 2 [Homo sa... 67 5e-11
gi|116174746 sentrin/SUMO-specific protease 7 isoform 1 [Homo sa... 67 5e-11
gi|215982794 myosin VA isoform 2 [Homo sapiens] 40 0.007
gi|6631100 natural killer-tumor recognition sequence [Homo sapiens] 39 0.011
gi|27886561 nuclear factor of activated T-cells, cytoplasmic, ca... 39 0.019
gi|27886559 nuclear factor of activated T-cells, cytoplasmic, ca... 39 0.019
gi|27886555 nuclear factor of activated T-cells, cytoplasmic, ca... 39 0.019
gi|4758804 nuclear factor of activated T-cells, cytoplasmic, cal... 39 0.019
gi|169208458 PREDICTED: similar to golgi autoantigen, golgin sub... 38 0.025
gi|154937324 hypothetical protein LOC440295 [Homo sapiens] 38 0.025
gi|31982906 cingulin-like 1 [Homo sapiens] 37 0.056
gi|217416374 hypothetical protein LOC92749 [Homo sapiens] 37 0.056
gi|239745259 PREDICTED: hypothetical protein isoform 2 [Homo sap... 37 0.073
gi|34577114 cytomatrix protein p110 [Homo sapiens] 37 0.073
gi|148746218 TAO kinase 3 [Homo sapiens] 37 0.073
gi|239743293 PREDICTED: mucin 12 [Homo sapiens] 36 0.13
gi|8923040 CDKN2A interacting protein [Homo sapiens] 36 0.13
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 36 0.13
gi|213688415 coiled-coil domain containing 66 isoform 1 [Homo sa... 36 0.13
gi|213688413 coiled-coil domain containing 66 isoform 2 [Homo sa... 36 0.13
gi|73623035 sperm associated antigen 5 [Homo sapiens] 35 0.21
gi|89026265 PREDICTED: mucin 12 [Homo sapiens] 35 0.28
gi|191252785 centrobin, centrosomal BRCA2 interacting protein is... 35 0.28
gi|80861396 centrobin, centrosomal BRCA2 interacting protein iso... 35 0.28
>gi|7657550 sentrin/SUMO-specific protease 1 [Homo sapiens]
Length = 643
Score = 1299 bits (3362), Expect = 0.0
Identities = 643/643 (100%), Positives = 643/643 (100%)
Query: 1 MDDIADRMRMDAGEVTLVNHNSVFKTHLLPQTGFPEDQLSLSDQQILSSRQGHLDRSFTC 60
MDDIADRMRMDAGEVTLVNHNSVFKTHLLPQTGFPEDQLSLSDQQILSSRQGHLDRSFTC
Sbjct: 1 MDDIADRMRMDAGEVTLVNHNSVFKTHLLPQTGFPEDQLSLSDQQILSSRQGHLDRSFTC 60
Query: 61 STRSAAYNPSYYSDNPSSDSFLGSGDLRTFGQSANGQWRNSTPSSSSSLQKSRNSRSLYL 120
STRSAAYNPSYYSDNPSSDSFLGSGDLRTFGQSANGQWRNSTPSSSSSLQKSRNSRSLYL
Sbjct: 61 STRSAAYNPSYYSDNPSSDSFLGSGDLRTFGQSANGQWRNSTPSSSSSLQKSRNSRSLYL 120
Query: 121 ETRKTSSGLSNSFAGKSNHHCHVSAYEKSFPIKPVPSPSWSGSCRRSLLSPKKTQRRHVS 180
ETRKTSSGLSNSFAGKSNHHCHVSAYEKSFPIKPVPSPSWSGSCRRSLLSPKKTQRRHVS
Sbjct: 121 ETRKTSSGLSNSFAGKSNHHCHVSAYEKSFPIKPVPSPSWSGSCRRSLLSPKKTQRRHVS 180
Query: 181 TAEETVQEEEREIYRQLLQMVTGKQFTIAKPTTHFPLHLSRCLSSSKNTLKDSLFKNGNS 240
TAEETVQEEEREIYRQLLQMVTGKQFTIAKPTTHFPLHLSRCLSSSKNTLKDSLFKNGNS
Sbjct: 181 TAEETVQEEEREIYRQLLQMVTGKQFTIAKPTTHFPLHLSRCLSSSKNTLKDSLFKNGNS 240
Query: 241 CASQIIGSDTSSSGSASILTNQEQLSHSVYSLSSYTPDVAFGSKDSGTLHHPHHHHSVPH 300
CASQIIGSDTSSSGSASILTNQEQLSHSVYSLSSYTPDVAFGSKDSGTLHHPHHHHSVPH
Sbjct: 241 CASQIIGSDTSSSGSASILTNQEQLSHSVYSLSSYTPDVAFGSKDSGTLHHPHHHHSVPH 300
Query: 301 QPDNLAASNTQSEGSDSVILLKVKDSQTPTPSSTFFQAELWIKELTSVYDSRARERLRQI 360
QPDNLAASNTQSEGSDSVILLKVKDSQTPTPSSTFFQAELWIKELTSVYDSRARERLRQI
Sbjct: 301 QPDNLAASNTQSEGSDSVILLKVKDSQTPTPSSTFFQAELWIKELTSVYDSRARERLRQI 360
Query: 361 EEQKALALQLQNQRLQEREHSVHDSVELHLRVPLEKEIPVTVVQETQKKGHKLTDSEDEF 420
EEQKALALQLQNQRLQEREHSVHDSVELHLRVPLEKEIPVTVVQETQKKGHKLTDSEDEF
Sbjct: 361 EEQKALALQLQNQRLQEREHSVHDSVELHLRVPLEKEIPVTVVQETQKKGHKLTDSEDEF 420
Query: 421 PEITEEMEKEIKNVFRNGNQDEVLSEAFRLTITRKDIQTLNHLNWLNDEIINFYMNMLME 480
PEITEEMEKEIKNVFRNGNQDEVLSEAFRLTITRKDIQTLNHLNWLNDEIINFYMNMLME
Sbjct: 421 PEITEEMEKEIKNVFRNGNQDEVLSEAFRLTITRKDIQTLNHLNWLNDEIINFYMNMLME 480
Query: 481 RSKEKGLPSVHAFNTFFFTKLKTAGYQAVKRWTKKVDVFSVDILLVPIHLGVHWCLAVVD 540
RSKEKGLPSVHAFNTFFFTKLKTAGYQAVKRWTKKVDVFSVDILLVPIHLGVHWCLAVVD
Sbjct: 481 RSKEKGLPSVHAFNTFFFTKLKTAGYQAVKRWTKKVDVFSVDILLVPIHLGVHWCLAVVD 540
Query: 541 FRKKNITYYDSMGGINNEACRILLQYLKQESIDKKRKEFDTNGWQLFSKKSQIPQQMNGS 600
FRKKNITYYDSMGGINNEACRILLQYLKQESIDKKRKEFDTNGWQLFSKKSQIPQQMNGS
Sbjct: 541 FRKKNITYYDSMGGINNEACRILLQYLKQESIDKKRKEFDTNGWQLFSKKSQIPQQMNGS 600
Query: 601 DCGMFACKYADCITKDRPINFTQQHMPYFRKRMVWEILHRKLL 643
DCGMFACKYADCITKDRPINFTQQHMPYFRKRMVWEILHRKLL
Sbjct: 601 DCGMFACKYADCITKDRPINFTQQHMPYFRKRMVWEILHRKLL 643
>gi|54607091 SUMO1/sentrin/SMT3 specific protease 2 [Homo sapiens]
Length = 589
Score = 294 bits (753), Expect = 1e-79
Identities = 144/298 (48%), Positives = 201/298 (67%), Gaps = 7/298 (2%)
Query: 353 ARERLRQIEEQKALALQLQNQRLQEREHSVHDSVELHLRVP------LEKEIPVTVVQET 406
++ ++ E + + +++R + E + + V LR+ L +++ + +E
Sbjct: 292 SKGKITDTETMVGIRFENESRRGYQLEPDLSEEVSARLRLGSGSNGLLRRKVSIIETKEK 351
Query: 407 QKKGHKLTDSEDEFPEITEEMEKEIKNVFRNGNQDEVLSEAFRLTITRKDIQTLNHLNWL 466
G + D+ E+TE+MEKEI N +G QDE+LS AF+L ITR DIQTL + +WL
Sbjct: 352 NCSGKERDRRTDDLLELTEDMEKEISNALGHGPQDEILSSAFKLRITRGDIQTLKNYHWL 411
Query: 467 NDEIINFYMNMLMERSKEKGLPSVHAFNTFFFTKLKTAGYQAVKRWTKKVDVFSVDILLV 526
NDE+INFYMN+L+ER+K++G P++H F+TFF+ KLK+ GYQAVKRWTK V++F +I+LV
Sbjct: 412 NDEVINFYMNLLVERNKKQGYPALHVFSTFFYPKLKSGGYQAVKRWTKGVNLFEQEIILV 471
Query: 527 PIHLGVHWCLAVVDFRKKNITYYDSMGGINNEACRILLQYLKQESIDKKRKEFDTNGWQL 586
PIH VHW L V+D RKK + Y DSMG + C ILLQYL+ ES K+ + + W
Sbjct: 472 PIHRKVHWSLVVIDLRKKCLKYLDSMGQKGHRICEILLQYLQDESKTKRNSDLNLLEWTH 531
Query: 587 FS-KKSQIPQQMNGSDCGMFACKYADCITKDRPINFTQQHMPYFRKRMVWEILHRKLL 643
S K +IPQQ+NGSDCGMF CKYAD I++D+PI FTQ MP FRK+MVWEILH++LL
Sbjct: 532 HSMKPHEIPQQLNGSDCGMFTCKYADYISRDKPITFTQHQMPLFRKKMVWEILHQQLL 589
Score = 31.2 bits (69), Expect = 3.1
Identities = 24/61 (39%), Positives = 36/61 (59%), Gaps = 6/61 (9%)
Query: 173 KTQRRHVSTAEETVQEEEREIYRQLLQMV--TGKQFTIAKPTTHFPLHLSRCLSSSKNTL 230
K RR T EE VQ+EERE YR+LL+ + +G ++ T+++ H S+ S +TL
Sbjct: 195 KGLRRPHCTVEEGVQKEEREKYRKLLERLKESGHGNSVCPVTSNY--HSSQ--RSQMDTL 250
Query: 231 K 231
K
Sbjct: 251 K 251
>gi|21361499 SUMO1/sentrin/SMT3 specific protease 3 [Homo sapiens]
Length = 574
Score = 170 bits (430), Expect = 4e-42
Identities = 83/194 (42%), Positives = 124/194 (63%), Gaps = 6/194 (3%)
Query: 449 RLTITRKDIQTLNHLNWLNDEIINFYMNMLMERSKEKGLPSVHAFNTFFFTKLKTAGYQA 508
R +T D+ TL NWLND+++N Y +++M+ EK VH FN+FF+ KL+T GY
Sbjct: 385 RHVLTMDDLGTLYGQNWLNDQVMNMYGDLVMDTVPEK----VHFFNSFFYDKLRTKGYDG 440
Query: 509 VKRWTKKVDVFSVDILLVPIHLGVHWCLAVVDFRKKNITYYDSMGGINNEACRILLQYLK 568
VKRWTK VD+F+ ++LL+PIHL VHW L VD R++ ITY+DS +N + + +YL+
Sbjct: 441 VKRWTKNVDIFNKELLLIPIHLEVHWSLISVDVRRRTITYFDSQRTLNRRCPKHIAKYLQ 500
Query: 569 QESIDKKRKEFDTNGWQLFSKKSQIPQQMNGSDCGMFACKYADCITKDRPINFTQQHMPY 628
E++ K R +F GW+ + K + + +Q N SDCG F +Y + +P +FTQQ MP
Sbjct: 501 AEAVKKDRLDFH-QGWKGYFKMN-VARQNNDSDCGAFVLQYCKHLALSQPFSFTQQDMPK 558
Query: 629 FRKRMVWEILHRKL 642
R+++ E+ H KL
Sbjct: 559 LRRQIYKELCHCKL 572
>gi|159032029 SUMO1/sentrin specific peptidase 5 [Homo sapiens]
Length = 755
Score = 159 bits (402), Expect = 8e-39
Identities = 82/188 (43%), Positives = 113/188 (60%), Gaps = 6/188 (3%)
Query: 456 DIQTLNHLNWLNDEIINFYMNMLMERSKEKGLPSVHAFNTFFFTKLKTAGYQAVKRWTKK 515
D+ TL+ NWLND++IN Y ++M+ +K VH FN+FF +L T GY VKRWTKK
Sbjct: 573 DLATLDGQNWLNDQVINMYGELIMDAVPDK----VHFFNSFFHRQLVTKGYNGVKRWTKK 628
Query: 516 VDVFSVDILLVPIHLGVHWCLAVVDFRKKNITYYDSMGGINNEACRILLQYLKQESIDKK 575
VD+F +LL+PIHL VHW L V + I++YDS G + +YL E+ +K
Sbjct: 629 VDLFKKSLLLIPIHLEVHWSLITVTLSNRIISFYDSQGIHFKFCVENIRKYLLTEAREKN 688
Query: 576 RKEFDTNGWQLFSKKSQIPQQMNGSDCGMFACKYADCITKDRPINFTQQHMPYFRKRMVW 635
R EF GWQ K IPQQ N SDCG+F +Y C+ ++P F+Q+ MP RKR+
Sbjct: 689 RPEF-LQGWQTAVTKC-IPQQKNDSDCGVFVLQYCKCLALEQPFQFSQEDMPRVRKRIYK 746
Query: 636 EILHRKLL 643
E+ +L+
Sbjct: 747 ELCECRLM 754
>gi|156105703 SUMO1/sentrin specific peptidase 6 isoform 2 [Homo
sapiens]
Length = 1105
Score = 70.9 bits (172), Expect = 4e-12
Identities = 46/169 (27%), Positives = 78/169 (46%), Gaps = 17/169 (10%)
Query: 450 LTITRKDIQTLNHLNWLNDEIINFYMNML-MERSKEKGLPSVHAFNTFFFTKL------- 501
+++T +D+ LN +LND II+FY+ L +E+ K++ +H F++FF+ +L
Sbjct: 659 ISVTNEDLHCLNEGEFLNDVIIDFYLKYLVLEKLKKEDADRIHIFSSFFYKRLNQRERRN 718
Query: 502 --------KTAGYQAVKRWTKKVDVFSVDILLVPIHLGVHWCLAVVDFRKKNITYYDSMG 553
+ + VK WT+ VD+F D + VP++ HW LAVV F Y+
Sbjct: 719 HETTNLSIQQKRHGRVKTWTRHVDIFEKDFIFVPLNEAAHWFLAVVCFPGLEKPKYEPNP 778
Query: 554 GINNEACRILLQYLKQESIDKKRKEFDTNGWQLFSKKSQIPQQMNGSDC 602
+ A ++ I E ++ Q S K I + +N C
Sbjct: 779 HYHENAVIQKCSTVEDSCISSSASEMESCS-QNSSAKPVIKKMLNKKHC 826
Score = 35.4 bits (80), Expect = 0.16
Identities = 23/89 (25%), Positives = 44/89 (49%), Gaps = 1/89 (1%)
Query: 534 WCLAVVDFRKKNITYYDSMGGIN-NEACRILLQYLKQESIDKKRKEFDTNGWQLFSKKSQ 592
W L ++ I DS+ G + + +IL +YL+ E KK + + + +
Sbjct: 954 WHLKPTICKQPCILLMDSLRGPSRSNVVKILREYLEVEWEVKKGSKRSFSKDVMKGSNPK 1013
Query: 593 IPQQMNGSDCGMFACKYADCITKDRPINF 621
+PQQ N SDCG++ +Y + ++ ++F
Sbjct: 1014 VPQQNNFSDCGVYVLQYVESFFENPILSF 1042
>gi|156105701 SUMO1/sentrin specific peptidase 6 isoform 1 [Homo
sapiens]
Length = 1112
Score = 70.9 bits (172), Expect = 4e-12
Identities = 46/169 (27%), Positives = 78/169 (46%), Gaps = 17/169 (10%)
Query: 450 LTITRKDIQTLNHLNWLNDEIINFYMNML-MERSKEKGLPSVHAFNTFFFTKL------- 501
+++T +D+ LN +LND II+FY+ L +E+ K++ +H F++FF+ +L
Sbjct: 666 ISVTNEDLHCLNEGEFLNDVIIDFYLKYLVLEKLKKEDADRIHIFSSFFYKRLNQRERRN 725
Query: 502 --------KTAGYQAVKRWTKKVDVFSVDILLVPIHLGVHWCLAVVDFRKKNITYYDSMG 553
+ + VK WT+ VD+F D + VP++ HW LAVV F Y+
Sbjct: 726 HETTNLSIQQKRHGRVKTWTRHVDIFEKDFIFVPLNEAAHWFLAVVCFPGLEKPKYEPNP 785
Query: 554 GINNEACRILLQYLKQESIDKKRKEFDTNGWQLFSKKSQIPQQMNGSDC 602
+ A ++ I E ++ Q S K I + +N C
Sbjct: 786 HYHENAVIQKCSTVEDSCISSSASEMESCS-QNSSAKPVIKKMLNKKHC 833
Score = 35.4 bits (80), Expect = 0.16
Identities = 23/89 (25%), Positives = 44/89 (49%), Gaps = 1/89 (1%)
Query: 534 WCLAVVDFRKKNITYYDSMGGIN-NEACRILLQYLKQESIDKKRKEFDTNGWQLFSKKSQ 592
W L ++ I DS+ G + + +IL +YL+ E KK + + + +
Sbjct: 961 WHLKPTICKQPCILLMDSLRGPSRSNVVKILREYLEVEWEVKKGSKRSFSKDVMKGSNPK 1020
Query: 593 IPQQMNGSDCGMFACKYADCITKDRPINF 621
+PQQ N SDCG++ +Y + ++ ++F
Sbjct: 1021 VPQQNNFSDCGVYVLQYVESFFENPILSF 1049
>gi|116174736 sentrin/SUMO-specific protease 7 isoform 2 [Homo
sapiens]
Length = 985
Score = 67.0 bits (162), Expect = 5e-11
Identities = 54/252 (21%), Positives = 106/252 (42%), Gaps = 80/252 (31%)
Query: 450 LTITRKDIQTLNHLNWLNDEIINFYMN-MLMERSKEKGLPSVHAFNTFFFT--------- 499
L +T +D++ L +LND II+FY+ +++E++ ++ + H F++FF+
Sbjct: 695 LGVTNEDLECLEEGEFLNDVIIDFYLKYLILEKASDELVERSHIFSSFFYKCLTRKENNL 754
Query: 500 -------KLKTAGYQAVKRWTKKVDVFSVDILLVPIHLGVHWCLAVVDF----------- 541
+ ++ V+ WT+ +++F+ D + VP++ HW LAV+ F
Sbjct: 755 TEDNPNLSMAQRRHKRVRTWTRHINIFNKDYIFVPVNESSHWYLAVICFPWLEEAVYEDF 814
Query: 542 ---------------------------RKKNITYYDSMGGINN---------EACRILLQ 565
+++ DS +N C ++L
Sbjct: 815 PQTVSQQSQAQQSQNDNKTIDNDLRTTSTLSLSAEDSQSTESNMSVPKKMCKRPCILILD 874
Query: 566 YLKQESID---KKRKEFDTNGWQL-------FSKKS------QIPQQMNGSDCGMFACKY 609
LK S+ + +E+ W++ FSK + ++P+Q N SDCG++ +Y
Sbjct: 875 SLKAASVQNTVQNLREYLEVEWEVKLKTHRQFSKTNMVDLCPKVPKQDNSSDCGVYLLQY 934
Query: 610 ADCITKDRPINF 621
+ KD +NF
Sbjct: 935 VESFFKDPIVNF 946
>gi|116174746 sentrin/SUMO-specific protease 7 isoform 1 [Homo
sapiens]
Length = 1050
Score = 67.0 bits (162), Expect = 5e-11
Identities = 54/252 (21%), Positives = 106/252 (42%), Gaps = 80/252 (31%)
Query: 450 LTITRKDIQTLNHLNWLNDEIINFYMN-MLMERSKEKGLPSVHAFNTFFFT--------- 499
L +T +D++ L +LND II+FY+ +++E++ ++ + H F++FF+
Sbjct: 760 LGVTNEDLECLEEGEFLNDVIIDFYLKYLILEKASDELVERSHIFSSFFYKCLTRKENNL 819
Query: 500 -------KLKTAGYQAVKRWTKKVDVFSVDILLVPIHLGVHWCLAVVDF----------- 541
+ ++ V+ WT+ +++F+ D + VP++ HW LAV+ F
Sbjct: 820 TEDNPNLSMAQRRHKRVRTWTRHINIFNKDYIFVPVNESSHWYLAVICFPWLEEAVYEDF 879
Query: 542 ---------------------------RKKNITYYDSMGGINN---------EACRILLQ 565
+++ DS +N C ++L
Sbjct: 880 PQTVSQQSQAQQSQNDNKTIDNDLRTTSTLSLSAEDSQSTESNMSVPKKMCKRPCILILD 939
Query: 566 YLKQESID---KKRKEFDTNGWQL-------FSKKS------QIPQQMNGSDCGMFACKY 609
LK S+ + +E+ W++ FSK + ++P+Q N SDCG++ +Y
Sbjct: 940 SLKAASVQNTVQNLREYLEVEWEVKLKTHRQFSKTNMVDLCPKVPKQDNSSDCGVYLLQY 999
Query: 610 ADCITKDRPINF 621
+ KD +NF
Sbjct: 1000 VESFFKDPIVNF 1011
>gi|215982794 myosin VA isoform 2 [Homo sapiens]
Length = 1828
Score = 40.0 bits (92), Expect = 0.007
Identities = 35/146 (23%), Positives = 72/146 (49%), Gaps = 10/146 (6%)
Query: 301 QPDNLAASNTQSEGSDSVILLKVKDSQTPTPSSTFFQAELWIKELTSVYDSRARERLRQI 360
Q + + + ++ +DS ILL+ D Q QA + +KE + +S+ + + R
Sbjct: 1276 QKEAIQPKDDKNTMTDSTILLE--DVQKMKDKGEIAQAYIGLKETNRLLESQLQSQKRS- 1332
Query: 361 EEQKALALQLQNQRLQEREHSVHDSVELHLRVPLEKEIPVTVVQETQKKGHKLTDSEDEF 420
E +A AL+ + Q L+E + + +L++P E I ++ H++T +E
Sbjct: 1333 HENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEASLQ-------HEITRLTNEN 1385
Query: 421 PEITEEMEKEIKNVFRNGNQDEVLSE 446
++ E++EK+ K V + Q +V ++
Sbjct: 1386 LDLMEQLEKQDKTVRKLKKQLKVFAK 1411
Score = 32.0 bits (71), Expect = 1.8
Identities = 37/155 (23%), Positives = 67/155 (43%), Gaps = 15/155 (9%)
Query: 343 KELTSVYDSRARERLRQIEEQKALALQLQNQRLQEREHSVHDSVELHLRVPLEKEIPVTV 402
KE+T + + +EE K L L L ++RL+ ++ +++ L R KE +T+
Sbjct: 1050 KEMTETMEKKL------VEETKQLELDLNDERLRY-QNLLNEFSRLEERYDDLKE-EMTL 1101
Query: 403 VQETQKKGHKLTDS-----EDEFPEITE--EMEKEIKNVFRNGNQDEVLSEAFRLTITRK 455
+ K GHK TDS E E+ +E EME + L + L + ++
Sbjct: 1102 MVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKR 1161
Query: 456 DIQTLNHLNWLNDEIINFYMNMLMERSKEKGLPSV 490
+ + DE+ +L ++KE+ P +
Sbjct: 1162 VTELEQEKQVMQDELDRKEEQVLRSKAKEEERPQI 1196
>gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]
Length = 1462
Score = 39.3 bits (90), Expect = 0.011
Identities = 57/223 (25%), Positives = 85/223 (38%), Gaps = 20/223 (8%)
Query: 56 RSFTCSTRSAAYNPSYYSDNPSSDSFLGSGDLRTFGQSANGQWRNSTPSSSSSLQKSRNS 115
RS + S+RS +Y+ SY + S S + S N +S S SSS +
Sbjct: 691 RSRSRSSRSRSYSRSYTRSRSLASSHSRSRSPSSRSHSRNKYSDHSQCSRSSSYTSISSD 750
Query: 116 RSLYLETRKTSSGLSNSFAGKSNHHCHVSAYEKSFPIKPVPSPSWSGSCR-----RSLLS 170
+ R SSG NS +H H S+ EK+ K V S R RS L
Sbjct: 751 DGRRAKRRLRSSGKKNSV----SHKKHSSSSEKTLHSKYVKGRDRSSCVRKYSESRSSLD 806
Query: 171 PKKTQRRHVSTAEETVQEEEREIYRQLLQMVTGKQFTIAKPTTHFPLHLSRCLSSSKNTL 230
+ A ++ QE+E++ + K K + C S K TL
Sbjct: 807 YSSDSEQSSVQATQSAQEKEKQGQMERTHNKQEKNRGEEKSKSE-----RECPHSKKRTL 861
Query: 231 KDSL---FKNGNS-CASQIIGS--DTSSSGSASILTNQEQLSH 267
K++L +NG+ GS D+ S+ + N + SH
Sbjct: 862 KENLSDHLRNGSKPKRKNYAGSKWDSESNSERDVTKNSKNDSH 904
Score = 35.4 bits (80), Expect = 0.16
Identities = 95/416 (22%), Positives = 162/416 (38%), Gaps = 53/416 (12%)
Query: 42 SDQQILSSRQGHLDRSFTCSTRSAAYNPSYYSDNPSSDSFLGSGDLRTFGQSAN-GQWRN 100
S ++ S + S T S+R SY S + S GS RT +S++ + R+
Sbjct: 495 SSKRDWSKSDKDVQSSLTHSSRD-----SYRSKSHSQSYSRGSSRSRTASKSSSHSRSRS 549
Query: 101 STPSSSSSLQKSRNSRSLYLETRKTSSGLSNSFAGKSNHHCHVSAYEKSFPIKPV----- 155
+ SSS S + R S+S RKT+S LS + K+ A ++ ++PV
Sbjct: 550 KSRSSSKSGHRKRASKS----PRKTASQLSENKPVKTEPLRATMAQNENVVVQPVVAENI 605
Query: 156 PSPSWSGSCRRSLLSPKKTQRRHVSTAEETVQEEEREIYRQLLQMVTGKQFTIAKPTTHF 215
P S S S P Q+ + Y ++ +M AK T
Sbjct: 606 PVIPLSDSPPPSRWKPG--------------QKPWKPSYERIQEMK-------AKTTHLL 644
Query: 216 PLHLSRCLSSSKNTLKDSLF--KNGNSCASQIIGSDTSSSGSASILTNQEQLSHSVYSLS 273
P+ + L++ K T S + + NS + Q S S S S ++ + S S
Sbjct: 645 PIQSTYSLANIKETGSSSSYHKREKNSESDQSTYSKYSDRSSESSPRSRSRSSRSRSYSR 704
Query: 274 SYTPDVAFGSKDSGTLHHPHHHHSVPHQPDNLAASNTQSEGSDSV-----ILLKVKDSQT 328
SYT + S S + HS D+ S + S S S +++ S
Sbjct: 705 SYTRSRSLASSHSRSRSPSSRSHSRNKYSDHSQCSRSSSYTSISSDDGRRAKRRLRSSGK 764
Query: 329 PTPSSTFFQAELWIKELTSVYDSRARER---LRQIEEQKALALQLQNQRLQEREHSVHDS 385
S + K L S Y + R+R +R+ E ++ +L + Q + +
Sbjct: 765 KNSVSHKKHSSSSEKTLHSKY-VKGRDRSSCVRKYSESRS-SLDYSSDSEQSSVQATQSA 822
Query: 386 VELHLRVPLEKEIPVTVVQETQKKGHKLTDSEDEFPEITEEMEKE-IKNVFRNGNQ 440
E + +E+ T ++ + +G + + SE E P + KE + + RNG++
Sbjct: 823 QEKEKQGQMER----THNKQEKNRGEEKSKSERECPHSKKRTLKENLSDHLRNGSK 874
>gi|27886561 nuclear factor of activated T-cells, cytoplasmic,
calcineurin-dependent 3 isoform 1 [Homo sapiens]
Length = 1075
Score = 38.5 bits (88), Expect = 0.019
Identities = 55/205 (26%), Positives = 80/205 (39%), Gaps = 30/205 (14%)
Query: 149 SFPIKPVPSP-------SWSGSCRRSLLSPKKTQRRHVSTAEETVQEEEREIYRQLLQM- 200
S P PVP P S SG S+LS QR + + +T + LQ
Sbjct: 714 SVPSLPVPHPAQTQRPSSDSGCSHDSVLSG---QRSLICSIPQTYASMVTSSHLPQLQCR 770
Query: 201 ---VTGKQFTIAKPTTHFPLHLSRC--LSSSKNTLKDSLFKNGNSCASQIIGSDTSSSGS 255
V+ +Q I P H P ++ + SS ++ ++ NG +C + SS
Sbjct: 771 DESVSKEQHMIPSPIVHQPFQVTPTPPVGSSYQPMQTNVVYNGPTCLPI---NAASSQEF 827
Query: 256 ASILTNQEQLSHSVYSLSSYT-PDVAFGSKDSGTLHH-----PHHHHSVPH-QPDNLAAS 308
S+L Q+ + +L + F S +SG+ H PH H++PH Q S
Sbjct: 828 DSVLFQQDATLSGLVNLGCQPLSSIPFHSSNSGSTGHLLAHTPHSVHTLPHLQSMGYHCS 887
Query: 309 NTQSEGSDSVILLKVKDSQTPTPSS 333
NT S V D T PSS
Sbjct: 888 NTGQRSLSS----PVADQITGQPSS 908
>gi|27886559 nuclear factor of activated T-cells, cytoplasmic,
calcineurin-dependent 3 isoform 4 [Homo sapiens]
Length = 1045
Score = 38.5 bits (88), Expect = 0.019
Identities = 55/205 (26%), Positives = 80/205 (39%), Gaps = 30/205 (14%)
Query: 149 SFPIKPVPSP-------SWSGSCRRSLLSPKKTQRRHVSTAEETVQEEEREIYRQLLQM- 200
S P PVP P S SG S+LS QR + + +T + LQ
Sbjct: 714 SVPSLPVPHPAQTQRPSSDSGCSHDSVLSG---QRSLICSIPQTYASMVTSSHLPQLQCR 770
Query: 201 ---VTGKQFTIAKPTTHFPLHLSRC--LSSSKNTLKDSLFKNGNSCASQIIGSDTSSSGS 255
V+ +Q I P H P ++ + SS ++ ++ NG +C + SS
Sbjct: 771 DESVSKEQHMIPSPIVHQPFQVTPTPPVGSSYQPMQTNVVYNGPTCLPI---NAASSQEF 827
Query: 256 ASILTNQEQLSHSVYSLSSYT-PDVAFGSKDSGTLHH-----PHHHHSVPH-QPDNLAAS 308
S+L Q+ + +L + F S +SG+ H PH H++PH Q S
Sbjct: 828 DSVLFQQDATLSGLVNLGCQPLSSIPFHSSNSGSTGHLLAHTPHSVHTLPHLQSMGYHCS 887
Query: 309 NTQSEGSDSVILLKVKDSQTPTPSS 333
NT S V D T PSS
Sbjct: 888 NTGQRSLSS----PVADQITGQPSS 908
>gi|27886555 nuclear factor of activated T-cells, cytoplasmic,
calcineurin-dependent 3 isoform 3 [Homo sapiens]
Length = 1065
Score = 38.5 bits (88), Expect = 0.019
Identities = 55/205 (26%), Positives = 80/205 (39%), Gaps = 30/205 (14%)
Query: 149 SFPIKPVPSP-------SWSGSCRRSLLSPKKTQRRHVSTAEETVQEEEREIYRQLLQM- 200
S P PVP P S SG S+LS QR + + +T + LQ
Sbjct: 714 SVPSLPVPHPAQTQRPSSDSGCSHDSVLSG---QRSLICSIPQTYASMVTSSHLPQLQCR 770
Query: 201 ---VTGKQFTIAKPTTHFPLHLSRC--LSSSKNTLKDSLFKNGNSCASQIIGSDTSSSGS 255
V+ +Q I P H P ++ + SS ++ ++ NG +C + SS
Sbjct: 771 DESVSKEQHMIPSPIVHQPFQVTPTPPVGSSYQPMQTNVVYNGPTCLPI---NAASSQEF 827
Query: 256 ASILTNQEQLSHSVYSLSSYT-PDVAFGSKDSGTLHH-----PHHHHSVPH-QPDNLAAS 308
S+L Q+ + +L + F S +SG+ H PH H++PH Q S
Sbjct: 828 DSVLFQQDATLSGLVNLGCQPLSSIPFHSSNSGSTGHLLAHTPHSVHTLPHLQSMGYHCS 887
Query: 309 NTQSEGSDSVILLKVKDSQTPTPSS 333
NT S V D T PSS
Sbjct: 888 NTGQRSLSS----PVADQITGQPSS 908
>gi|4758804 nuclear factor of activated T-cells, cytoplasmic,
calcineurin-dependent 3 isoform 2 [Homo sapiens]
Length = 1068
Score = 38.5 bits (88), Expect = 0.019
Identities = 55/205 (26%), Positives = 80/205 (39%), Gaps = 30/205 (14%)
Query: 149 SFPIKPVPSP-------SWSGSCRRSLLSPKKTQRRHVSTAEETVQEEEREIYRQLLQM- 200
S P PVP P S SG S+LS QR + + +T + LQ
Sbjct: 714 SVPSLPVPHPAQTQRPSSDSGCSHDSVLSG---QRSLICSIPQTYASMVTSSHLPQLQCR 770
Query: 201 ---VTGKQFTIAKPTTHFPLHLSRC--LSSSKNTLKDSLFKNGNSCASQIIGSDTSSSGS 255
V+ +Q I P H P ++ + SS ++ ++ NG +C + SS
Sbjct: 771 DESVSKEQHMIPSPIVHQPFQVTPTPPVGSSYQPMQTNVVYNGPTCLPI---NAASSQEF 827
Query: 256 ASILTNQEQLSHSVYSLSSYT-PDVAFGSKDSGTLHH-----PHHHHSVPH-QPDNLAAS 308
S+L Q+ + +L + F S +SG+ H PH H++PH Q S
Sbjct: 828 DSVLFQQDATLSGLVNLGCQPLSSIPFHSSNSGSTGHLLAHTPHSVHTLPHLQSMGYHCS 887
Query: 309 NTQSEGSDSVILLKVKDSQTPTPSS 333
NT S V D T PSS
Sbjct: 888 NTGQRSLSS----PVADQITGQPSS 908
>gi|169208458 PREDICTED: similar to golgi autoantigen, golgin
subfamily a-like [Homo sapiens]
Length = 432
Score = 38.1 bits (87), Expect = 0.025
Identities = 38/142 (26%), Positives = 68/142 (47%), Gaps = 18/142 (12%)
Query: 337 QAELWIKELTSVYDSRARERLRQIEE----------QKALALQLQNQRLQEREHSVHDSV 386
QAE+ ++ S+ + R ERLR+ EE ++ L Q +RL+E+E + +
Sbjct: 181 QAEVENNQMLSLLNRRQEERLREQEERLREQEERLCEQEERLCEQEERLREQEERLCEQE 240
Query: 387 ELHLRVPLEKEIPVTVVQE-TQKKGHKLTDSEDEFPEITEEMEKEIKNVFRNGNQDEVL- 444
+L + L +E+ + QE Q++ +L + E E+ E +E+E R QDE L
Sbjct: 241 KLPGQERLLEEVEKLLKQERRQEEQERLLERERLLDEVEELLEQE-----RLRQQDERLW 295
Query: 445 -SEAFRLTITRKDIQTLNHLNW 465
E R ++++ + L W
Sbjct: 296 QQETLRELERLRELERMLELGW 317
>gi|154937324 hypothetical protein LOC440295 [Homo sapiens]
Length = 432
Score = 38.1 bits (87), Expect = 0.025
Identities = 38/142 (26%), Positives = 68/142 (47%), Gaps = 18/142 (12%)
Query: 337 QAELWIKELTSVYDSRARERLRQIEE----------QKALALQLQNQRLQEREHSVHDSV 386
QAE+ ++ S+ + R ERLR+ EE ++ L Q +RL+E+E + +
Sbjct: 181 QAEVENNQMLSLLNRRQEERLREQEERLREQEERLCEQEERLCEQEERLREQEERLCEQE 240
Query: 387 ELHLRVPLEKEIPVTVVQE-TQKKGHKLTDSEDEFPEITEEMEKEIKNVFRNGNQDEVL- 444
+L + L +E+ + QE Q++ +L + E E+ E +E+E R QDE L
Sbjct: 241 KLPGQERLLEEVEKLLKQERRQEEQERLLERERLLDEVEELLEQE-----RLRQQDERLW 295
Query: 445 -SEAFRLTITRKDIQTLNHLNW 465
E R ++++ + L W
Sbjct: 296 QQETLRELERLRELERMLELGW 317
>gi|31982906 cingulin-like 1 [Homo sapiens]
Length = 1302
Score = 37.0 bits (84), Expect = 0.056
Identities = 35/131 (26%), Positives = 60/131 (45%), Gaps = 9/131 (6%)
Query: 304 NLAASNTQSEGSDSVILLKVKDSQTPTPSSTFFQAELWIKELTSVYDSRAR-----ERLR 358
N A N+ SE D LL+ K T + Q +L +K ++ + R R E LR
Sbjct: 599 NNQACNSTSEVKD---LLEQKSKLTIEVAELQRQLQLEVKNQQNIKEERERMRANLEELR 655
Query: 359 QIEEQKALALQLQNQRLQEREHSVHDSVELHLRVPLEKEIPVTVVQETQKKGHKLTDSED 418
+K QRL+E E + ++E +V +E+E T +++ Q + ++ D D
Sbjct: 656 SQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMEREQHQTEIRDLQDQLSEMHDELD 715
Query: 419 EFPEITEEMEK 429
+ +E+ EK
Sbjct: 716 S-AKRSEDREK 725
>gi|217416374 hypothetical protein LOC92749 [Homo sapiens]
Length = 740
Score = 37.0 bits (84), Expect = 0.056
Identities = 37/144 (25%), Positives = 71/144 (49%), Gaps = 16/144 (11%)
Query: 354 RERLRQIEEQKALALQLQN------QRLQEREHSVH---DSVELHLRVPLEKEIPVTVVQ 404
R+R+ EE + ++L+ Q+LQ+R+ + +E +L+V +++ TV++
Sbjct: 275 RQRIWDCEEYNMIKIKLEQDVQILEQQLQQRKAIYQLNQEKLEYNLQVLKKRDEESTVIK 334
Query: 405 ETQKKGHKLTDSEDEFPEITEEMEKEIKNVFRNGNQDEVLSEAFRLTITRKDIQ-TLNHL 463
QK+ K+ D + + K+IK F+ NQ + S+ RL + K++Q + H
Sbjct: 335 SQQKR--KINRLHDILNNLRSKYAKQIKQ-FQEENQ-SLTSDYKRLVMQFKELQKAMRHF 390
Query: 464 NWLNDEIINFYMNMLMERSKEKGL 487
++DE F+ LM + K L
Sbjct: 391 ALIDDE--KFWEIWLMNEEEAKDL 412
>gi|239745259 PREDICTED: hypothetical protein isoform 2 [Homo
sapiens]
Length = 432
Score = 36.6 bits (83), Expect = 0.073
Identities = 38/142 (26%), Positives = 67/142 (47%), Gaps = 18/142 (12%)
Query: 337 QAELWIKELTSVYDSRARERLRQIEE----------QKALALQLQNQRLQEREHSVHDSV 386
QAE+ ++ S+ + R ERLR+ EE ++ L Q +RL E+E + +
Sbjct: 181 QAEVENNQMLSLLNRRQEERLREQEERLREQEERLHEQEERLCEQEERLCEQEERLCEQE 240
Query: 387 ELHLRVPLEKEIPVTVVQE-TQKKGHKLTDSEDEFPEITEEMEKEIKNVFRNGNQDEVL- 444
+L + L +E+ + QE Q++ +L + E E+ E +E+E R QDE L
Sbjct: 241 KLPGQERLLEEVEKLLEQERRQEEQERLLERERLLDEVEELLEQE-----RLRQQDERLW 295
Query: 445 -SEAFRLTITRKDIQTLNHLNW 465
E R ++++ + L W
Sbjct: 296 QQETLRELERLRELERMLELGW 317
>gi|34577114 cytomatrix protein p110 [Homo sapiens]
Length = 957
Score = 36.6 bits (83), Expect = 0.073
Identities = 71/292 (24%), Positives = 121/292 (41%), Gaps = 45/292 (15%)
Query: 213 THFPLHLSRCLSSSKNTLKDSLFKNGNSCASQIIGSDTSSSGSASILTNQEQLSHSVYSL 272
T P++LS + T G + + G ++ GS+ + + LSH+ +
Sbjct: 58 TSGPMYLSDHEGVASTTYPKGTMTLGRATNRAVYGGRVTAMGSSPNIASAG-LSHT--DV 114
Query: 273 SSYTPDVAFGSKDSGTLHHPHHHHSVPHQPDNLAAS----------NTQSEGSDSVILLK 322
SYT D G +G+ HH HHH VP + S Q E L
Sbjct: 115 LSYT-DQHGGL--TGSSHH--HHHQVPSMLRQVRDSTMLDLQAQLKELQRENDLLRKELD 169
Query: 323 VKDSQTPTPSSTFFQAELWIKELTSVYDSRARE--RLRQIEEQKALALQLQNQRLQEREH 380
+KDS+ + ++ W EL R E R+ ++EQ ++ + +NQ LQ
Sbjct: 170 IKDSKLGSSMNSI--KTFWSPELKKERVLRKEEAARMSVLKEQMRVSHE-ENQHLQLTIQ 226
Query: 381 SVHDSVELHLRVPLEKEIPVTVVQETQKKGHK---LTDSEDEFPEITEEMEKEIKNVFRN 437
++ D + ++++ + QE+ +G + + +E+ F + E +++ K +F
Sbjct: 227 ALQDELR------TQRDLNHLLQQESGNRGAEHFTIELTEENFRRLQAEHDRQAKELFL- 279
Query: 438 GNQDEVLSEAFRLTITRKDIQTLNHLNWLNDEIINFYMNMLMERSKEKGLPS 489
+ L E T+K QTLN DE I L+E + KGLPS
Sbjct: 280 --LRKTLEEMELRIETQK--QTLN----ARDESI----KKLLEMLQSKGLPS 319
Score = 30.0 bits (66), Expect = 6.9
Identities = 27/96 (28%), Positives = 44/96 (45%), Gaps = 16/96 (16%)
Query: 355 ERLRQIEEQKALALQLQNQRLQEREHSVHDSVELHLRVPLEKEIPVTVVQET--QKKGHK 412
ER R++ E ++ L+ Q+ + ++H ELH R L+ E T +T + K K
Sbjct: 327 ERTRRMAEAESQVSHLEVILDQKEKENIHLREELHRRSQLQPEPAKTKALQTVIEMKDTK 386
Query: 413 LT-------DSEDEFPEI-------TEEMEKEIKNV 434
+ D EDE + TE+ E+EIK +
Sbjct: 387 IASLERNIRDLEDEIQMLKANGVLNTEDREEEIKQI 422
>gi|148746218 TAO kinase 3 [Homo sapiens]
Length = 898
Score = 36.6 bits (83), Expect = 0.073
Identities = 30/123 (24%), Positives = 58/123 (47%), Gaps = 4/123 (3%)
Query: 319 ILLKVKDSQTPTPSSTFFQAELWIKELTSVYDSRARERLRQIEEQKALALQLQNQRLQER 378
IL +KD QT + Q E I E+ + S+A RL + +E + AL+LQ Q+ E
Sbjct: 753 ILKTLKDEQTRKLAILAEQYEQSINEMMA---SQAL-RLDEAQEAECQALRLQLQQEMEL 808
Query: 379 EHSVHDSVELHLRVPLEKEIPVTVVQETQKKGHKLTDSEDEFPEITEEMEKEIKNVFRNG 438
++ +++ E+E+ + + ++ H E+E + +E + IKN+
Sbjct: 809 LNAYQSKIKMQTEAQHERELQKLEQRVSLRRAHLEQKIEEELAALQKERSERIKNLLERQ 868
Query: 439 NQD 441
++
Sbjct: 869 ERE 871
>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
Length = 5478
Score = 35.8 bits (81), Expect = 0.13
Identities = 68/307 (22%), Positives = 105/307 (34%), Gaps = 43/307 (14%)
Query: 53 HLDRSFTCSTRSAAYNPSYYSDNPSSDSFLGSGDLRTFGQSANGQWRNSTPSSSSSLQKS 112
H S +T + P+ Y +P S + D T +G+ ST S SS
Sbjct: 4589 HTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSST----TSGRSEESTASHSSQ---- 4640
Query: 113 RNSRSLYLETRKTSSGL--SNSFAGKSNHHCHVSAYEKSFPIKPVPSPSWSGSCRRSLLS 170
+ ++ L R T+S L ++ + S+ +A S +P S S
Sbjct: 4641 DATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGS-----TTTPGLSEKSTTFHSS 4695
Query: 171 PKKTQRRHVSTAEETVQEEEREIYRQLLQMVTGKQFTIAKPTTHFPLHLSRCLSSSKNTL 230
P T H S + T+ E + T + A+ TT + S SS +
Sbjct: 4696 PSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGST 4755
Query: 231 KDSLFKNGNSCASQIIGSDTSSSGSASILTNQEQLSHSVYSLSSYTPDVAFGSKDSGTLH 290
+ F S T+S S T+ +H++ S S T S +
Sbjct: 4756 QTMHFPE----------SSTASGRSEESRTSHSSTTHTISSPPSTT---------SALVE 4796
Query: 291 HPHHHHSVP------HQPDNLAASNTQSEGSDSVILLKVKDSQTPTPSSTFFQAELWIKE 344
P +HS P H P+ +S T +S D+ TP F I E
Sbjct: 4797 EPTSYHSSPGSIATTHFPE---SSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAE 4853
Query: 345 LTSVYDS 351
T+ Y S
Sbjct: 4854 STTFYIS 4860
Score = 33.9 bits (76), Expect = 0.48
Identities = 71/315 (22%), Positives = 105/315 (33%), Gaps = 46/315 (14%)
Query: 14 EVTLVNHNSVFKTHLLPQTGFPEDQLSLSDQQILSSRQGHLDRSFTCSTRSAAYNPSYYS 73
E + +H+ TH T FP Q S H T +T S + + S
Sbjct: 3274 EESTTSHSRPGSTHT---TAFPGSTTMPGVSQ--ESTASHSSPGSTDTTLSPG-STTASS 3327
Query: 74 DNPSSDSF-LGSGDLRTF----GQSANGQWRNSTPSSSSSLQKSRNSRSLYLETRKTSSG 128
P S +F G G T +A+G STP SS+ +L T G
Sbjct: 3328 LGPESTTFHSGPGSTETTLLPDNTTASGLLEASTPVHSST---GSPHTTLSPAGSTTRQG 3384
Query: 129 LSNSFAGKSNHHCHVSAYEKSFPIKPVPSPSWSGSCRRSLLSPKKTQRRHVSTAEETVQE 188
S +F N + + P P + ++ S SP T H S + T+
Sbjct: 3385 ESTTFQSWPNS-------KDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGR 3437
Query: 189 EEREIYRQLLQMVTGKQFTIAKPTTHFPLHLSRCLSSSKNTLKDSLFKNGNSCASQIIGS 248
E + T + A+ TT + S SS + + F S
Sbjct: 3438 SEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPE----------S 3487
Query: 249 DTSSSGSASILTNQEQLSHSVYSLSSYTPDVAFGSKDSGTLHHPHHHHSVP------HQP 302
DT+S T+ +H++ S S T S + P +HS P H P
Sbjct: 3488 DTTSGRGEESTTSHSSTTHTISSAPSTT---------SALVEEPTSYHSSPGSTATTHFP 3538
Query: 303 DNLAASNTQSEGSDS 317
D+ S E + S
Sbjct: 3539 DSSTTSGRSEESTAS 3553
Score = 32.3 bits (72), Expect = 1.4
Identities = 52/231 (22%), Positives = 79/231 (34%), Gaps = 35/231 (15%)
Query: 93 SANGQWRNSTPSSSSSLQKSRNSRSLYLETRKTSSGLSNSFAGKSNHHCHVSAYEKSFPI 152
+A+G STP SS+ +L T G S +F N + + P
Sbjct: 4435 TASGLLEASTPVHSST---GSPHTTLSPAGSTTRQGESTTFQSWPNS-------KDTTPA 4484
Query: 153 KPVPSPSWSGSCRRSLLSPKKTQRRHVSTAEETVQEEEREIYRQLLQMVTGKQFTIAKPT 212
P + ++ S SP T H S + T+ E + T + A+ T
Sbjct: 4485 PPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARST 4544
Query: 213 THFPLHLSRCLSSSKNTLKDSLFKNGNSCASQIIGSDTSSSGSASILTNQEQLSHSVYSL 272
T + S SS + + F N+ TS G S T+ +H++ S
Sbjct: 4545 TSGLVEESTTYHSSPGSTQTMHFPESNT---------TSGRGEES-TTSHSSTTHTISSA 4594
Query: 273 SSYTPDVAFGSKDSGTLHHPHHHHSVP------HQPDNLAASNTQSEGSDS 317
S T S + P +HS P H PD+ S E + S
Sbjct: 4595 PSTT---------SALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTAS 4636
Score = 31.6 bits (70), Expect = 2.4
Identities = 49/231 (21%), Positives = 76/231 (32%), Gaps = 35/231 (15%)
Query: 93 SANGQWRNSTPSSSSSLQKSRNSRSLYLETRKTSSGLSNSFAGKSNHHCHVSAYEKSFPI 152
+A+G STP SS+ TR+ S S+ + + P
Sbjct: 1795 TASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKD----------TMPA 1844
Query: 153 KPVPSPSWSGSCRRSLLSPKKTQRRHVSTAEETVQEEEREIYRQLLQMVTGKQFTIAKPT 212
P + ++ S SP T H S + T+ E + T + A+ T
Sbjct: 1845 PPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARST 1904
Query: 213 THFPLHLSRCLSSSKNTLKDSLFKNGNSCASQIIGSDTSSSGSASILTNQEQLSHSVYSL 272
T + S SS + + F S T+S S T+ +H++ S
Sbjct: 1905 TSGLVEESTAYHSSPGSTQTMHFPE----------SSTASGRSEESRTSHSSTTHTISSP 1954
Query: 273 SSYTPDVAFGSKDSGTLHHPHHHHSVP------HQPDNLAASNTQSEGSDS 317
S T S + P +HS P H PD+ S E + S
Sbjct: 1955 PSTT---------SALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTAS 1996
>gi|8923040 CDKN2A interacting protein [Homo sapiens]
Length = 580
Score = 35.8 bits (81), Expect = 0.13
Identities = 51/216 (23%), Positives = 95/216 (43%), Gaps = 16/216 (7%)
Query: 77 SSDSFLGSGDLRTFGQSANGQWRNSTPSSSSSLQKSRNSRSLYLETRKTSSGLSNSFAGK 136
+S + +GS G SA +S SS+S +S +S+S + SS ++ + +GK
Sbjct: 174 NSSTCIGSAIKSESGNSARSSGISSQNSSTSDGDRSVSSQS----SSSVSSQVTTAGSGK 229
Query: 137 SNH----HCHVSAYEKSFPIKPVPSP-SWSGSCRRSLLSPKKTQRRHVSTAEETVQEEER 191
++ H SA S V S + S R+ SPKK+ + + + +
Sbjct: 230 ASEAEAPDKHGSASFVSLLKSSVNSHMTQSTDSRQQSGSPKKSA---LEGSSASASQSSS 286
Query: 192 EIYRQLLQMVTGKQFTI----AKPTTHFPLHLSRCLSSSKNTLKDSLFKNGNSCASQIIG 247
EI LL + + +KP++ +SS+ ++ S+ KN +S + ++
Sbjct: 287 EIEVPLLGSSGSSEVELPLLSSKPSSETASSGLTSKTSSEASVSSSVAKNSSSSGTSLLT 346
Query: 248 SDTSSSGSASILTNQEQLSHSVYSLSSYTPDVAFGS 283
+SSS + S+LT++ + L+S + GS
Sbjct: 347 PKSSSSTNTSLLTSKSTSQVAASLLASKSSSQTSGS 382
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 35.8 bits (81), Expect = 0.13
Identities = 28/119 (23%), Positives = 53/119 (44%), Gaps = 21/119 (17%)
Query: 337 QAELWIKELTSVYDSRARERLRQIEEQKALALQLQNQRLQEREHSVHDSVELHLRVPLEK 396
+ E +K LT VY+S+ + ++ E+ K + ++ +N LQ RE +K
Sbjct: 876 EMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQ-------------KK 922
Query: 397 EIPVTVVQETQKKGHKLTDSEDEFPEITEEMEKEIKNVFRNGNQDEVLSEAFRLTITRK 455
EI + KL+ ED + EE E + KN + + + ++ + T+ +K
Sbjct: 923 EIEILT--------QKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKK 973
>gi|213688415 coiled-coil domain containing 66 isoform 1 [Homo
sapiens]
Length = 948
Score = 35.8 bits (81), Expect = 0.13
Identities = 93/439 (21%), Positives = 168/439 (38%), Gaps = 55/439 (12%)
Query: 88 RTFGQSANGQWRNSTPS----SSSSLQKSRNSRSLYLETRKTSSGLSNSFAGKSNHHCHV 143
R+ + NG+ S S S S+ K N L+ +T SS + + + + H
Sbjct: 169 RSLSLTENGKEAKSQYSLYLNSISNQPKDENIMGLFKKTEMVSSVPAENKSVLNEHQETS 228
Query: 144 SAYEKSFPI----KPVPSPSWSGS--CRRSLLSPKKTQRRHVSTAEETVQEEEREIYRQL 197
E+ I KP S G C RS L KK Q R + ++++E+E+ +
Sbjct: 229 KQCEQKIAIENEWKPADIFSTLGERECDRSSLEAKKAQWRKELDEQVALKKKEKEVSEKW 288
Query: 198 LQMVTGKQFTIAKPTTHFPLHLSR---CLSSSKNTLKDSLFKNGNSCASQIIGSDTSSSG 254
+ H L SR L + +K L + ++ I D
Sbjct: 289 NDPWKKSESDKIIWEKHQILDQSRETVLLEHPFSAVKQELQRKWIEELNKQIEDDRQRKI 348
Query: 255 SASILTNQ----EQLSHSVYSLSSYTPDVAFGSKD---SGTLHHPHHHHSVPHQPDNLA- 306
I+ ++ ++ + SL SY GS+ S + H + V LA
Sbjct: 349 EEKIIYSKGEEHDRWAMHFDSLKSYP-----GSQSQLFSQSTHKQPEYFCVSPDTQELAD 403
Query: 307 -------ASNTQSEGSDSVILLK-VKDSQTPTPSSTFFQAELWIKELTSVYDSRARERLR 358
+ +Q E S+ + K +KD T F + + + R R R +
Sbjct: 404 VSSVCTPTTGSQVEPSEEEHIAKPIKDVVMANSKKTNFLRSMTALLDPAQIEERDRRRQK 463
Query: 359 QIEEQKALALQLQNQRL-----QEREHSVHDSVELHL---RVPLEKEIPVTVVQETQK-- 408
Q+E QKA+ Q++ +R +E+ EL L R ++K+ ++++ QK
Sbjct: 464 QLEHQKAITAQVEEKRRKKQLEEEQRKKEEQEEELRLAQEREEMQKQYEEDILKQKQKEE 523
Query: 409 ----KGHKLTDSEDEFPEITEEMEKE--IKNVFRNGNQDEVLSEAFRLTITRKDIQTLNH 462
K ++L + E+ + +++E I+ + + G+ L + + + + N
Sbjct: 524 IMTLKTNELFQTMQRAQELAQRLKQEQRIRELAQKGHDTSRLIKNLGVDTIQMEYNASNI 583
Query: 463 LNWL--NDEI---INFYMN 476
N +DEI +N YMN
Sbjct: 584 SNSRHDSDEISGKMNTYMN 602
>gi|213688413 coiled-coil domain containing 66 isoform 2 [Homo
sapiens]
Length = 914
Score = 35.8 bits (81), Expect = 0.13
Identities = 93/439 (21%), Positives = 168/439 (38%), Gaps = 55/439 (12%)
Query: 88 RTFGQSANGQWRNSTPS----SSSSLQKSRNSRSLYLETRKTSSGLSNSFAGKSNHHCHV 143
R+ + NG+ S S S S+ K N L+ +T SS + + + + H
Sbjct: 135 RSLSLTENGKEAKSQYSLYLNSISNQPKDENIMGLFKKTEMVSSVPAENKSVLNEHQETS 194
Query: 144 SAYEKSFPI----KPVPSPSWSGS--CRRSLLSPKKTQRRHVSTAEETVQEEEREIYRQL 197
E+ I KP S G C RS L KK Q R + ++++E+E+ +
Sbjct: 195 KQCEQKIAIENEWKPADIFSTLGERECDRSSLEAKKAQWRKELDEQVALKKKEKEVSEKW 254
Query: 198 LQMVTGKQFTIAKPTTHFPLHLSR---CLSSSKNTLKDSLFKNGNSCASQIIGSDTSSSG 254
+ H L SR L + +K L + ++ I D
Sbjct: 255 NDPWKKSESDKIIWEKHQILDQSRETVLLEHPFSAVKQELQRKWIEELNKQIEDDRQRKI 314
Query: 255 SASILTNQ----EQLSHSVYSLSSYTPDVAFGSKD---SGTLHHPHHHHSVPHQPDNLA- 306
I+ ++ ++ + SL SY GS+ S + H + V LA
Sbjct: 315 EEKIIYSKGEEHDRWAMHFDSLKSYP-----GSQSQLFSQSTHKQPEYFCVSPDTQELAD 369
Query: 307 -------ASNTQSEGSDSVILLK-VKDSQTPTPSSTFFQAELWIKELTSVYDSRARERLR 358
+ +Q E S+ + K +KD T F + + + R R R +
Sbjct: 370 VSSVCTPTTGSQVEPSEEEHIAKPIKDVVMANSKKTNFLRSMTALLDPAQIEERDRRRQK 429
Query: 359 QIEEQKALALQLQNQRL-----QEREHSVHDSVELHL---RVPLEKEIPVTVVQETQK-- 408
Q+E QKA+ Q++ +R +E+ EL L R ++K+ ++++ QK
Sbjct: 430 QLEHQKAITAQVEEKRRKKQLEEEQRKKEEQEEELRLAQEREEMQKQYEEDILKQKQKEE 489
Query: 409 ----KGHKLTDSEDEFPEITEEMEKE--IKNVFRNGNQDEVLSEAFRLTITRKDIQTLNH 462
K ++L + E+ + +++E I+ + + G+ L + + + + N
Sbjct: 490 IMTLKTNELFQTMQRAQELAQRLKQEQRIRELAQKGHDTSRLIKNLGVDTIQMEYNASNI 549
Query: 463 LNWL--NDEI---INFYMN 476
N +DEI +N YMN
Sbjct: 550 SNSRHDSDEISGKMNTYMN 568
>gi|73623035 sperm associated antigen 5 [Homo sapiens]
Length = 1193
Score = 35.0 bits (79), Expect = 0.21
Identities = 40/182 (21%), Positives = 80/182 (43%), Gaps = 17/182 (9%)
Query: 320 LLKVKDSQTPTPSSTFFQAELWIKELTSVYD--SRARERLRQIEEQKALALQLQNQRLQE 377
++ ++ ++TP + + + EL S+ ++E + ++K LQ + Q +E
Sbjct: 955 MVSLQPAETPGMEESLAEMSIMTTELQSLCSLLQESKEEAIRTLQRKICELQARLQAQEE 1014
Query: 378 REHSVHDSVE---------LHLRVPLEKEIPVTVVQETQKKGHKLTDSEDEFPEITEEME 428
+ V + E L LR EKE+ + Q+ +K ++ D E + EE+
Sbjct: 1015 QHQEVQKAKEADIEKLNQALCLRYKNEKELQEVIQQQNEKILEQI-DKSGELISLREEVT 1073
Query: 429 KEIKNVFRNGNQDEVLSEAF--RLTITRKDIQT--LNHLNWLNDEIINFYMNML-MERSK 483
+++ R + +VL EA +L + + T + WL+ E+ + L M+ K
Sbjct: 1074 HLTRSLRRAETETKVLQEALAGQLDSNCQPMATNWIQEKVWLSQEVDKLRVMFLEMKNEK 1133
Query: 484 EK 485
EK
Sbjct: 1134 EK 1135
>gi|89026265 PREDICTED: mucin 12 [Homo sapiens]
Length = 978
Score = 34.7 bits (78), Expect = 0.28
Identities = 79/349 (22%), Positives = 116/349 (33%), Gaps = 49/349 (14%)
Query: 14 EVTLVNHNSVFKTHLLPQTGFPEDQLSLSDQQILSSRQGHLDRSFTCSTRSAAYNPSYYS 73
E + +H+ TH T FP Q S H T +T S + + S
Sbjct: 53 EESTTSHSRPGSTHT---TAFPGSTTMPGVSQ--ESTASHSSPGSTDTTLSPG-STTASS 106
Query: 74 DNPSSDSF-LGSGDLRTF----GQSANGQWRNSTPSSSSSLQKSRNSRSLYLETRKTSSG 128
P S +F G G T +A+G STP SS+ +L T G
Sbjct: 107 LGPESTTFHSGPGSTETTLLPDNTTASGLLEASTPVHSST---GSPHTTLSPAGSTTRQG 163
Query: 129 LSNSFAGKSNHHCHVSAYEKSFPIKPVPSPSWSGSCRRSLLSPKKTQRRHVSTAEETVQE 188
S +F N + + P P + ++ S SP T H S + T+
Sbjct: 164 ESTTFQSWPNS-------KDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGR 216
Query: 189 EEREIYRQLLQMVTGKQFTIAKPTTHFPLHLSRCLSSSKNTLKDSLFKNGNSCASQIIGS 248
E + T + A+ TT + S SS + + F S
Sbjct: 217 SEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPE----------S 266
Query: 249 DTSSSGSASILTNQEQLSHSVYSLSSYTPDVAFGSKDSGTLHHPHHHHSVP------HQP 302
T+S S T+ +H++ S S T S + P +HS P H P
Sbjct: 267 STASGRSEESRTSHSSTTHTISSPPSTT---------SALVEEPTSYHSSPGSIATTHFP 317
Query: 303 DNLAASNTQSEGSDSVILLKVKDSQTPTPSSTFFQAELWIKELTSVYDS 351
+ +S T +S D+ TP F I E T+ Y S
Sbjct: 318 E---SSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYIS 363
>gi|191252785 centrobin, centrosomal BRCA2 interacting protein
isoform alpha [Homo sapiens]
Length = 903
Score = 34.7 bits (78), Expect = 0.28
Identities = 35/131 (26%), Positives = 60/131 (45%), Gaps = 3/131 (2%)
Query: 301 QPDNLAASNTQSEGSDSVILLKVKDSQTPTPSSTFFQ-AELWIKELTSVYDSRARERLR- 358
Q ++ AA T+S+ ++V L+ S+ + + A L +E ++ + R LR
Sbjct: 261 QEEHQAAELTRSKQQETVTRLEQSLSEAMEALNREQESARLQQRERETLEEERQALTLRL 320
Query: 359 QIEEQKALALQLQNQRLQEREHSVHDSVELHLRVPLEKEIPVTVVQETQKKGHKLTDSED 418
+ E+Q+ LQ + + + S H +E LR LE+E QE Q K H E+
Sbjct: 321 EAEQQRCCVLQEERDAARAGQLSEHRELET-LRAALEEERQTWAQQEHQLKEHYQALQEE 379
Query: 419 EFPEITEEMEK 429
++ E EK
Sbjct: 380 SQAQLEREKEK 390
>gi|80861396 centrobin, centrosomal BRCA2 interacting protein
isoform beta [Homo sapiens]
Length = 925
Score = 34.7 bits (78), Expect = 0.28
Identities = 35/131 (26%), Positives = 60/131 (45%), Gaps = 3/131 (2%)
Query: 301 QPDNLAASNTQSEGSDSVILLKVKDSQTPTPSSTFFQ-AELWIKELTSVYDSRARERLR- 358
Q ++ AA T+S+ ++V L+ S+ + + A L +E ++ + R LR
Sbjct: 261 QEEHQAAELTRSKQQETVTRLEQSLSEAMEALNREQESARLQQRERETLEEERQALTLRL 320
Query: 359 QIEEQKALALQLQNQRLQEREHSVHDSVELHLRVPLEKEIPVTVVQETQKKGHKLTDSED 418
+ E+Q+ LQ + + + S H +E LR LE+E QE Q K H E+
Sbjct: 321 EAEQQRCCVLQEERDAARAGQLSEHRELET-LRAALEEERQTWAQQEHQLKEHYQALQEE 379
Query: 419 EFPEITEEMEK 429
++ E EK
Sbjct: 380 SQAQLEREKEK 390
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.129 0.375
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,600,836
Number of Sequences: 37866
Number of extensions: 1122448
Number of successful extensions: 6115
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 26
Number of HSP's successfully gapped in prelim test: 142
Number of HSP's that attempted gapping in prelim test: 5738
Number of HSP's gapped (non-prelim): 461
length of query: 643
length of database: 18,247,518
effective HSP length: 109
effective length of query: 534
effective length of database: 14,120,124
effective search space: 7540146216
effective search space used: 7540146216
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.