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Search of human proteins with 7657289
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7657289 potassium channel, subfamily V, member 1 [Homo
sapiens]
(500 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7657289 potassium channel, subfamily V, member 1 [Homo sapiens] 994 0.0
gi|27436974 potassium voltage-gated channel, Shab-related subfam... 387 e-107
gi|4826784 potassium voltage-gated channel, Shab-related subfami... 377 e-104
gi|45383011 potassium voltage-gated channel, delayed-rectifier, ... 346 2e-95
gi|25952108 potassium voltage-gated channel delayed-rectifier pr... 345 4e-95
gi|19424136 potassium channel, subfamily V, member 2 [Homo sapiens] 321 8e-88
gi|13492973 potassium voltage-gated channel delayed-rectifier pr... 316 4e-86
gi|27436988 potassium voltage-gated channel, subfamily G, member... 284 2e-76
gi|27436996 potassium voltage-gated channel, subfamily G, member... 277 1e-74
gi|6912444 potassium voltage-gated channel, subfamily G, member ... 273 3e-73
gi|27436993 potassium voltage-gated channel, subfamily G, member... 270 2e-72
gi|20070166 potassium voltage-gated channel, subfamily F, member... 269 5e-72
gi|19071574 potassium voltage-gated channel, subfamily G, member... 266 4e-71
gi|27436981 potassium voltage-gated channel, Shal-related subfam... 251 1e-66
gi|88758576 Shaw-related voltage-gated potassium channel protein... 240 2e-63
gi|24497462 Shaw-related voltage-gated potassium channel protein... 240 2e-63
gi|24497464 Shaw-related voltage-gated potassium channel protein... 240 2e-63
gi|9789987 potassium voltage-gated channel, Shal-related subfami... 231 9e-61
gi|21217561 Shaw-related voltage-gated potassium channel protein... 229 3e-60
gi|21217563 Shaw-related voltage-gated potassium channel protein... 229 3e-60
gi|24497458 Shaw-related voltage-gated potassium channel protein... 229 3e-60
gi|27436984 potassium voltage-gated channel, Shal-related subfam... 226 5e-59
gi|27436986 potassium voltage-gated channel, Shal-related subfam... 226 5e-59
gi|4826786 Shaw-related voltage-gated potassium channel protein ... 224 1e-58
gi|163792201 Shaw-related voltage-gated potassium channel protei... 224 1e-58
gi|4504817 potassium voltage-gated channel, shaker-related subfa... 219 6e-57
gi|119395748 potassium voltage-gated channel subfamily A member ... 216 4e-56
gi|5031819 potassium voltage-gated channel, shaker-related subfa... 214 2e-55
gi|4826782 potassium voltage-gated channel, shaker-related subfa... 211 1e-54
gi|88758565 potassium voltage-gated channel, shaker-related subf... 209 5e-54
>gi|7657289 potassium channel, subfamily V, member 1 [Homo sapiens]
Length = 500
Score = 994 bits (2570), Expect = 0.0
Identities = 500/500 (100%), Positives = 500/500 (100%)
Query: 1 MPSSGRALLDSPLDSGSLTSLDSSVFCSEGEGEPLALGDCFTVNVGGSRFVLSQQALSCF 60
MPSSGRALLDSPLDSGSLTSLDSSVFCSEGEGEPLALGDCFTVNVGGSRFVLSQQALSCF
Sbjct: 1 MPSSGRALLDSPLDSGSLTSLDSSVFCSEGEGEPLALGDCFTVNVGGSRFVLSQQALSCF 60
Query: 61 PHTRLGKLAVVVASYRRPGALAAVPSPLELCDDANPVDNEYFFDRSSQAFRYVLHYYRTG 120
PHTRLGKLAVVVASYRRPGALAAVPSPLELCDDANPVDNEYFFDRSSQAFRYVLHYYRTG
Sbjct: 61 PHTRLGKLAVVVASYRRPGALAAVPSPLELCDDANPVDNEYFFDRSSQAFRYVLHYYRTG 120
Query: 121 RLHVMEQLCALSFLQEIQYWGIDELSIDSCCRDRYFRRKELSETLDFKKDTEDQESQHES 180
RLHVMEQLCALSFLQEIQYWGIDELSIDSCCRDRYFRRKELSETLDFKKDTEDQESQHES
Sbjct: 121 RLHVMEQLCALSFLQEIQYWGIDELSIDSCCRDRYFRRKELSETLDFKKDTEDQESQHES 180
Query: 181 EQDFSQGPCPTVRQKLWNILEKPGSSTAARIFGVISIIFVVVSIINMALMSAELSWLDLQ 240
EQDFSQGPCPTVRQKLWNILEKPGSSTAARIFGVISIIFVVVSIINMALMSAELSWLDLQ
Sbjct: 181 EQDFSQGPCPTVRQKLWNILEKPGSSTAARIFGVISIIFVVVSIINMALMSAELSWLDLQ 240
Query: 241 LLEILEYVCISWFTGEFVLRFLCVRDRCRFLRKVPNIIDLLAILPFYITLLVESLSGSQT 300
LLEILEYVCISWFTGEFVLRFLCVRDRCRFLRKVPNIIDLLAILPFYITLLVESLSGSQT
Sbjct: 241 LLEILEYVCISWFTGEFVLRFLCVRDRCRFLRKVPNIIDLLAILPFYITLLVESLSGSQT 300
Query: 301 TQELENVGRIVQVLRLLRALRMLKLGRHSTGLRSLGMTITQCYEEVGLLLLFLSVGISIF 360
TQELENVGRIVQVLRLLRALRMLKLGRHSTGLRSLGMTITQCYEEVGLLLLFLSVGISIF
Sbjct: 301 TQELENVGRIVQVLRLLRALRMLKLGRHSTGLRSLGMTITQCYEEVGLLLLFLSVGISIF 360
Query: 361 STVEYFAEQSIPDTTFTSVPCAWWWATTSMTTVGYGDIRPDTTTGKIVAFMCILSGILVL 420
STVEYFAEQSIPDTTFTSVPCAWWWATTSMTTVGYGDIRPDTTTGKIVAFMCILSGILVL
Sbjct: 361 STVEYFAEQSIPDTTFTSVPCAWWWATTSMTTVGYGDIRPDTTTGKIVAFMCILSGILVL 420
Query: 421 ALPIAIINDRFSACYFTLKLKEAAVRQREALKKLTKNIATDSYISVNLRDVYARSIMEML 480
ALPIAIINDRFSACYFTLKLKEAAVRQREALKKLTKNIATDSYISVNLRDVYARSIMEML
Sbjct: 421 ALPIAIINDRFSACYFTLKLKEAAVRQREALKKLTKNIATDSYISVNLRDVYARSIMEML 480
Query: 481 RLKGRERASTRSSGGDDFWF 500
RLKGRERASTRSSGGDDFWF
Sbjct: 481 RLKGRERASTRSSGGDDFWF 500
>gi|27436974 potassium voltage-gated channel, Shab-related
subfamily, member 2 [Homo sapiens]
Length = 911
Score = 387 bits (993), Expect = e-107
Identities = 212/468 (45%), Positives = 311/468 (66%), Gaps = 34/468 (7%)
Query: 43 VNVGGSRFVLSQQALSCFPHTRLGKLAVVVASYRRPGALAAVPSPLELCDDANPVDNEYF 102
+NVGG + + L P TRLGKL S LE+CDD N +NEYF
Sbjct: 39 INVGGLNHEVLWRTLDRLPRTRLGKLRDCNTH----------ESLLEVCDDYNLNENEYF 88
Query: 103 FDRSSQAFRYVLHYYRTGRLHVMEQLCALSFLQEIQYWGIDELSIDSCCRDRYFRRKE-L 161
FDR AF +L++YRTG+LH+ME++CALSF QE+ YWGIDE+ ++SCC+ RY ++KE +
Sbjct: 89 FDRHPGAFTSILNFYRTGKLHMMEEMCALSFGQELDYWGIDEIYLESCCQARYHQKKEQM 148
Query: 162 SETLDFKKDTEDQESQHESE-QDFSQGPCPTVRQKLWNILEKPGSSTAARIFGVISIIFV 220
+E L + E+ E E ++F CP R+KLW++LEKP SS AA+I ++SI+F+
Sbjct: 149 NEEL-----RREAETMREREGEEFDNTCCPDKRKKLWDLLEKPNSSVAAKILAIVSILFI 203
Query: 221 VVSIINMALMSA-------ELSWL-DLQLLEILEYVCISWFTGEFVLRFLCVRDRCRFLR 272
V+S I ++L + E L D + L +E VCI+WFT E++LRFL ++ +F +
Sbjct: 204 VLSTIALSLNTLPELQETDEFGQLNDNRQLAHVEAVCIAWFTMEYLLRFLSSPNKWKFFK 263
Query: 273 KVPNIIDLLAILPFYITLLVESLSGSQTTQELENVGRIVQVLRLLRALRMLKLGRHSTGL 332
N+IDLLAILP+Y+T+ + +++ + +NV R+VQ+ R++R LR+LKL RHSTGL
Sbjct: 264 GPLNVIDLLAILPYYVTIFLTE--SNKSVLQFQNVRRVVQIFRIMRILRILKLARHSTGL 321
Query: 333 RSLGMTITQCYEEVGLLLLFLSVGISIFSTVEYFAEQSIPDTTFTSVPCAWWWATTSMTT 392
+SLG T+ + Y E+GLL+LFL++GI IFS++ +FAE+ T FTS+P ++WWAT +MTT
Sbjct: 322 QSLGFTLRRSYNELGLLILFLAMGIMIFSSLVFFAEKDEDATKFTSIPASFWWATITMTT 381
Query: 393 VGYGDIRPDTTTGKIVAFMCILSGILVLALPIAIINDRFSACYFTLKLKEAAVRQREALK 452
VGYGDI P T GKIV +C ++G+LV+ALPI II + FS Y K +E A+++REAL+
Sbjct: 382 VGYGDIYPKTLLGKIVGGLCCIAGVLVIALPIPIIVNNFSEFYKEQKRQEKAIKRREALE 441
Query: 453 KLTKNIATDSYISVNLRDVYARSIMEMLRL---KGRERASTRSSGGDD 497
+ +N S +S+NL+D +ARS ME++ + K E A+T+ S D+
Sbjct: 442 RAKRN---GSIVSMNLKDAFARS-MELIDVAVEKAGESANTKDSADDN 485
>gi|4826784 potassium voltage-gated channel, Shab-related subfamily,
member 1 [Homo sapiens]
Length = 858
Score = 377 bits (968), Expect = e-104
Identities = 206/446 (46%), Positives = 293/446 (65%), Gaps = 28/446 (6%)
Query: 43 VNVGGSRFVLSQQALSCFPHTRLGKLAVVVASYRRPGALAAVPSPLELCDDANPVDNEYF 102
+NVGG + + L P TRLGKL S LE+CDD + DNEYF
Sbjct: 35 LNVGGLAHEVLWRTLDRLPRTRLGKLRDCNTH----------DSLLEVCDDYSLDDNEYF 84
Query: 103 FDRSSQAFRYVLHYYRTGRLHVMEQLCALSFLQEIQYWGIDELSIDSCCRDRYFRRKELS 162
FDR AF +L++YRTGRLH+ME++CALSF QE+ YWGIDE+ ++SCC+ RY ++KE
Sbjct: 85 FDRHPGAFTSILNFYRTGRLHMMEEMCALSFSQELDYWGIDEIYLESCCQARYHQKKEQM 144
Query: 163 ETLDFKKDTEDQESQHESEQDFSQGPCPTVRQKLWNILEKPGSSTAARIFGVISIIFVVV 222
+ K++ E + E F C R+KLW++LEKP SS AA+I +ISI+F+V+
Sbjct: 145 NE-ELKREAETLREREGEE--FDNTCCAEKRKKLWDLLEKPNSSVAAKILAIISIMFIVL 201
Query: 223 SIINMALMSA-ELSWLDL--------QLLEILEYVCISWFTGEFVLRFLCVRDRCRFLRK 273
S I ++L + EL LD QL + E VCI+WFT E++LRFL + +F +
Sbjct: 202 STIALSLNTLPELQSLDEFGQSTDNPQLAHV-EAVCIAWFTMEYLLRFLSSPKKWKFFKG 260
Query: 274 VPNIIDLLAILPFYITLLVESLSGSQTTQELENVGRIVQVLRLLRALRMLKLGRHSTGLR 333
N IDLLAILP+Y+T+ + +++ + +NV R+VQ+ R++R LR+LKL RHSTGL+
Sbjct: 261 PLNAIDLLAILPYYVTIFLTE--SNKSVLQFQNVRRVVQIFRIMRILRILKLARHSTGLQ 318
Query: 334 SLGMTITQCYEEVGLLLLFLSVGISIFSTVEYFAEQSIPDTTFTSVPCAWWWATTSMTTV 393
SLG T+ + Y E+GLL+LFL++GI IFS++ +FAE+ DT F S+P ++WWAT +MTTV
Sbjct: 319 SLGFTLRRSYNELGLLILFLAMGIMIFSSLVFFAEKDEDDTKFKSIPASFWWATITMTTV 378
Query: 394 GYGDIRPDTTTGKIVAFMCILSGILVLALPIAIINDRFSACYFTLKLKEAAVRQREALKK 453
GYGDI P T GKIV +C ++G+LV+ALPI II + FS Y K +E A+++REAL++
Sbjct: 379 GYGDIYPKTLLGKIVGGLCCIAGVLVIALPIPIIVNNFSEFYKEQKRQEKAIKRREALER 438
Query: 454 LTKNIATDSYISVNLRDVYARSIMEM 479
+N S +S+N++D +ARSI M
Sbjct: 439 AKRN---GSIVSMNMKDAFARSIEMM 461
>gi|45383011 potassium voltage-gated channel, delayed-rectifier,
subfamily S, member 2 [Homo sapiens]
Length = 477
Score = 346 bits (888), Expect = 2e-95
Identities = 202/462 (43%), Positives = 270/462 (58%), Gaps = 50/462 (10%)
Query: 43 VNVGGSRFVLSQQALSCFPHTRLGKLAVVVASYRRPGALAAVPSPLELCDDANPVDNEYF 102
+NVGG + L L FP TRLG+L + + + LELCDD + V E++
Sbjct: 21 INVGGFKRRLRSHTLLRFPETRLGRLLLCHSR----------EAILELCDDYDDVQREFY 70
Query: 103 FDRSSQAFRYVLHYYRTGRLHVMEQLCALSFLQEIQYWGIDELSIDSCCRDRYFRRK--E 160
FDR+ + F YVLH+Y TG+LHVM +LC SF QEI+YWGI+E IDSCC Y RK
Sbjct: 71 FDRNPELFPYVLHFYHTGKLHVMAELCVFSFSQEIEYWGINEFFIDSCCSYSYHGRKVEP 130
Query: 161 LSETLDFKKDTEDQESQ-------HESEQDFSQGPCPTVRQKLWNILEKPGSSTAARIFG 213
E D + D E S + F P R++LW L+ PG S +R+F
Sbjct: 131 EQEKWDEQSDQESTTSSFDEILAFYNDASKFDGQPLGNFRRQLWLALDNPGYSVLSRVFS 190
Query: 214 VISIIFVVVSIINMALMSAELSWLDLQL------------LEILEYVCISWFTGEFVLRF 261
++SI+ V+ SII M L S D Q+ EI+E+ I+WFT E V RF
Sbjct: 191 ILSILVVMGSIITMCLNSLP----DFQIPDSQGNPGEDPRFEIVEHFGIAWFTFELVARF 246
Query: 262 LCVRDRCRFLRKVPNIIDLLAILPFYITLLVESLSGSQTTQELENVGRIVQVLRLLRALR 321
D +F + N+IDL++I+PFYITL+V + ++T L N+GR+ QVLRL+R R
Sbjct: 247 AVAPDFLKFFKNALNLIDLMSIVPFYITLVVNLV--VESTPTLANLGRVAQVLRLMRIFR 304
Query: 322 MLKLGRHSTGLRSLGMTITQCYEEVGLLLLFLSVGISIFSTVEYFAEQSIPDTTFTSVPC 381
+LKL RHSTGLRSLG T+ Y+EVGLLLL+LSVGISIFS V Y E+ + ++P
Sbjct: 305 ILKLARHSTGLRSLGATLKYSYKEVGLLLLYLSVGISIFSVVAYTIEKE-ENEGLATIPA 363
Query: 382 AWWWATTSMTTVGYGDIRPDTTTGKIVAFMCILSGILVLALPIAIINDRFSACYFTLKLK 441
WWWAT SMTTVGYGD+ P TT GK+ A CIL+GILV+ LPI +I ++FS Y K
Sbjct: 364 CWWWATVSMTTVGYGDVVPGTTAGKLTASACILAGILVVVLPITLIFNKFSHFYRRQKQL 423
Query: 442 EAAVRQ---REALKKLTKNIATDSYISVNLRDVYARSIMEML 480
E+A+R + +K++ SVNLRD YA + ++
Sbjct: 424 ESAMRSCDFGDGMKEVP---------SVNLRDYYAHKVKSLM 456
>gi|25952108 potassium voltage-gated channel delayed-rectifier
protein S3 [Homo sapiens]
Length = 491
Score = 345 bits (886), Expect = 4e-95
Identities = 192/446 (43%), Positives = 267/446 (59%), Gaps = 32/446 (7%)
Query: 43 VNVGGSRFVLSQQALSCFPHTRLGKLAVVVASYRRPGALAAVPSPLELCDDANPVDNEYF 102
+NVGG + + Q L FPHTRLGKL + + LELCDD + D EY+
Sbjct: 19 LNVGGFKQSVDQSTLLRFPHTRLGKLLTCHSE----------EAILELCDDYSVADKEYY 68
Query: 103 FDRSSQAFRYVLHYYRTGRLHVMEQLCALSFLQEIQYWGIDELSIDSCCRDRYFRRKELS 162
FDR+ FRYVL++Y TG+LHVME+LC SF QEI+YWGI+EL IDSCC +RY RKE +
Sbjct: 69 FDRNPSLFRYVLNFYYTGKLHVMEELCVFSFCQEIEYWGINELFIDSCCSNRYQERKEEN 128
Query: 163 ETLDFKKDTEDQESQHESEQD---------FSQGPCPTVRQKLWNILEKPGSSTAARIFG 213
D+ + + D + E+ F +R+K+W +E P +A++
Sbjct: 129 HEKDWDQKSHDVSTDSSFEESSLFEKELEKFDTLRFGQLRKKIWIRMENPAYCLSAKLIA 188
Query: 214 VISIIFVVVSIINMALMSA-----ELSWLDLQLLEILEYVCISWFTGEFVLRFLCVRDRC 268
+ S+ V+ SI+ M + S E +D +LE +E CI+WFTGE +R +
Sbjct: 189 ISSLSVVLASIVAMCVHSMSEFQNEDGEVDDPVLEGVEIACIAWFTGELAVRLAAAPCQK 248
Query: 269 RFLRKVPNIIDLLAILPFYITLLVESLSGSQTTQELENVGRIVQVLRLLRALRMLKLGRH 328
+F + NIID ++I+PFY TL V++ + ++++EN+G++VQ+LRL+R R+LKL RH
Sbjct: 249 KFWKNPLNIIDFVSIIPFYATLAVDTKE--EESEDIENMGKVVQILRLMRIFRILKLARH 306
Query: 329 STGLRSLGMTITQCYEEVGLLLLFLSVGISIFSTVEYFAEQSIPDTTFTSVPCAWWWATT 388
S GLRSLG T+ Y EVGLLLLFLSVGISIFS + Y E+ ++ TS+P WWWAT
Sbjct: 307 SVGLRSLGATLRHSYHEVGLLLLFLSVGISIFSVLIYSVEKDDHTSSLTSIPICWWWATI 366
Query: 389 SMTTVGYGDIRPDTTTGKIVAFMCILSGILVLALPIAIINDRFSACYFTLKLKEAAVRQR 448
SMTTVGYGD P T GK++A CI+ GILV+ALPI II ++FS Y K +
Sbjct: 367 SMTTVGYGDTHPVTLAGKLIASTCIICGILVVALPITIIFNKFSKYYQKQKDIDVDQCSE 426
Query: 449 EALKKLTKNIATDSYISVNLRDVYAR 474
+A +K N+RD+YA+
Sbjct: 427 DAPEK------CHELPYFNIRDIYAQ 446
>gi|19424136 potassium channel, subfamily V, member 2 [Homo sapiens]
Length = 545
Score = 321 bits (823), Expect = 8e-88
Identities = 182/441 (41%), Positives = 260/441 (58%), Gaps = 33/441 (7%)
Query: 29 EGEGEPLALGDCFTVNVGGSRFVLSQQALSCFPHTRLGKLAVVVASYRRPGALAAVPSPL 88
EG +P AL VNVGG + L L+ FP TRLG+LA + R+ L
Sbjct: 87 EGPSDPPALLSTLNVNVGGHSYQLDYCELAGFPKTRLGRLATSTSRSRQ----------L 136
Query: 89 ELCDDANPVDNEYFFDRSSQAFRYVLHYYRTGRLHVMEQLCALSFLQEIQYWGIDELSID 148
LCDD +EYFFDR F+ V ++Y +G L V++ LC FL+E+ YWG+
Sbjct: 137 SLCDDYEEQTDEYFFDRDPAVFQLVYNFYLSGVLLVLDGLCPRRFLEELGYWGVRLKYTP 196
Query: 149 SCCRDRYF-RRKELSETLDFKKDTEDQESQHESEQDFSQ----GPCPTVRQKLWNILEKP 203
CCR + RR ELSE L + + Q E+E+ F GP R++LWN++EKP
Sbjct: 197 RCCRICFEERRDELSERLKIQHELRAQAQVEEAEELFRDMRFYGP---QRRRLWNLMEKP 253
Query: 204 GSSTAARIFGVISIIFVVVSIINMALMSAELSWL---------DLQ-LLEILEYVCISWF 253
SS AA+ GV S FV+VS++ +AL + E DL+ +LE +E +C+ +F
Sbjct: 254 FSSVAAKAIGVASSTFVLVSVVALALNTVEEMQQHSGQGEGGPDLRPILEHVEMLCMGFF 313
Query: 254 TGEFVLRFLCVRDRCRFLRKVPNIIDLLAILPFYITLLVESLSGS-----QTTQELENVG 308
T E++LR D RF R N++DL+AILP Y+ LL+E +G QT + VG
Sbjct: 314 TLEYLLRLASTPDLRRFARSALNLVDLVAILPLYLQLLLECFTGEGHQRGQTVGSVGKVG 373
Query: 309 RIVQVLRLLRALRMLKLGRHSTGLRSLGMTITQCYEEVGLLLLFLSVGISIFSTVEYFAE 368
++++V+RL+R R+LKL RHSTGLR+ G T+ QCY++VG LLLF+++GI FS Y E
Sbjct: 374 QVLRVMRLMRIFRILKLARHSTGLRAFGFTLRQCYQQVGCLLLFIAMGIFTFSAAVYSVE 433
Query: 369 QSIPDTTFTSVPCAWWWATTSMTTVGYGDIRPDTTTGKIVAFMCILSGILVLALPIAIIN 428
+P T FT++P +WWWA S++TVGYGD+ P+T G+ AF+CI GI++ +PI+I+
Sbjct: 434 HDVPSTNFTTIPHSWWWAAVSISTVGYGDMYPETHLGRFFAFLCIAFGIILNGMPISILY 493
Query: 429 DRFSACYFTLKLKEAAVRQRE 449
++FS Y LK E +RE
Sbjct: 494 NKFSDYYSKLKAYEYTTIRRE 514
>gi|13492973 potassium voltage-gated channel delayed-rectifier
protein S1 [Homo sapiens]
Length = 526
Score = 316 bits (809), Expect = 4e-86
Identities = 190/475 (40%), Positives = 259/475 (54%), Gaps = 50/475 (10%)
Query: 6 RALLDSPLDSGSLTSLDSSVFCSEGEGEPLAL-----GDCFTVNVGGSRFVLSQQALSCF 60
+ +L +PL S + F SE G + + VNVGG R LS +AL+ F
Sbjct: 17 KVVLPTPLGGRS-----TETFVSEFPGPDTGIRWRRSDEALRVNVGGVRRQLSARALARF 71
Query: 61 PHTRLGKLAVVVASYRRPGALAAVPSPLELCDDANPVDNEYFFDRSSQAFRYVLHYYRTG 120
P TRLG+L A A+ LCDD + E++FDR F +LH+YRTG
Sbjct: 72 PGTRLGRLQ----------AAASEEQARRLCDDYDEAAREFYFDRHPGFFLSLLHFYRTG 121
Query: 121 RLHVMEQLCALSFLQEIQYWGIDELSIDSCCRDRYFRRK--------ELSETLDFKKDTE 172
LHV+++LC +F QE YWG+ E ++ +CCR RY R+ E S+T
Sbjct: 122 HLHVLDELCVFAFGQEADYWGLGENALAACCRARYLERRLTQPHAWDEDSDTPSSVDPCP 181
Query: 173 DQESQHESE-QDFSQGPCPTVRQKLWNILEKPGSSTAARIFGVISIIFVVVSIINMALMS 231
D+ S + E + C +R++LW +E PG S +++F +SI V+ SI M + S
Sbjct: 182 DEISDVQRELARYGAARCGRLRRRLWLTMENPGYSLPSKLFSCVSISVVLASIAAMCIHS 241
Query: 232 --------------------AELSWLDLQLLEILEYVCISWFTGEFVLRFLCVRDRCRFL 271
+ D +L LEY CI+WF+ E R L F
Sbjct: 242 LPEYQAREAAAAVAAVAAGRSPEGVRDDPVLRRLEYFCIAWFSFEVSSRLLLAPSTRNFF 301
Query: 272 RKVPNIIDLLAILPFYITLLVESLSGSQTTQELENVGRIVQVLRLLRALRMLKLGRHSTG 331
N+ID++++LPFY+TLL G Q +E ++G++VQV RL+R R+LKL RHSTG
Sbjct: 302 CHPLNLIDIVSVLPFYLTLLAGVALGDQGGKEFGHLGKVVQVFRLMRIFRVLKLARHSTG 361
Query: 332 LRSLGMTITQCYEEVGLLLLFLSVGISIFSTVEYFAEQSIPDTTFTSVPCAWWWATTSMT 391
LRSLG T+ Y EVG+LLL+L+VG+S+FS V Y AE+ D F ++P WWW T SMT
Sbjct: 362 LRSLGATLKHSYREVGILLLYLAVGVSVFSGVAYTAEKE-EDVGFNTIPACWWWGTVSMT 420
Query: 392 TVGYGDIRPDTTTGKIVAFMCILSGILVLALPIAIINDRFSACYFTLKLKEAAVR 446
TVGYGD+ P T GK+ A CIL GILV+ALPI II ++FS Y K EAAVR
Sbjct: 421 TVGYGDVVPVTVAGKLAASGCILGGILVVALPITIIFNKFSHFYRRQKALEAAVR 475
>gi|27436988 potassium voltage-gated channel, subfamily G, member 1
[Homo sapiens]
Length = 513
Score = 284 bits (726), Expect = 2e-76
Identities = 163/429 (37%), Positives = 253/429 (58%), Gaps = 34/429 (7%)
Query: 43 VNVGGSRFVLSQQALSCFPHTRLGKLAVVVASYRRPGALAAVPSPLELCDDANPVDNEYF 102
+NVGG ++ L L FP TRLG+L A L +CDD + NE+F
Sbjct: 67 INVGGIKYSLPWTTLDEFPLTRLGQLK----------ACTNFDDILNVCDDYDVTCNEFF 116
Query: 103 FDRSSQAFRYVLHYYRTGRLHVMEQLCALSFLQEIQYWGIDELSIDSCCRDRYFRR-KEL 161
FDR+ AF +L + R G+L ++ ++CALSF +E+ YWGI E +D CC+ RY ++ +E
Sbjct: 117 FDRNPGAFGTILTFLRAGKLRLLREMCALSFQEELLYWGIAEDHLDGCCKRRYLQKIEEF 176
Query: 162 SETLDFKK-----DTEDQESQHESEQDFSQGPCPTVRQKLWNILEKPGSSTAARIFGVIS 216
+E ++ ++ D+E ++S+ +E + G C ++L +++E+P S ++F +S
Sbjct: 177 AEMVEREEEDDALDSEGRDSEGPAEGEGRLGRC---MRRLRDMVERPHSGLPGKVFACLS 233
Query: 217 IIFVVVSIINM------ALMSAELSWLDLQLLE---ILEYVCISWFTGEFVLRFLCVRDR 267
++FV V+ +N+ +L E Q+ I+E VC+ WF+ EF+LR + +
Sbjct: 234 VLFVTVTAVNLSVSTLPSLREEEEQGHCSQMCHNVFIVESVCVGWFSLEFLLRLIQAPSK 293
Query: 268 CRFLRKVPNIIDLLAILPFYITLLVESLSGSQT-----TQELENVGRIVQVLRLLRALRM 322
FLR +IDL+AILP+YITLLV+ + + L+ VG +++VLR LR L +
Sbjct: 294 FAFLRSPLTLIDLVAILPYYITLLVDGAAAGRRKPGAGNSYLDKVGLVLRVLRALRILYV 353
Query: 323 LKLGRHSTGLRSLGMTITQCYEEVGLLLLFLSVGISIFSTVEYFAEQSIPDT-TFTSVPC 381
++L RHS GL++LG+T +C E GLLLLFL V I++F+ + Y E + D+ FTS+P
Sbjct: 354 MRLARHSLGLQTLGLTARRCTREFGLLLLFLCVAIALFAPLLYVIENEMADSPEFTSIPA 413
Query: 382 AWWWATTSMTTVGYGDIRPDTTTGKIVAFMCILSGILVLALPIAIINDRFSACYFTLKLK 441
+WWA +MTTVGYGD+ P +T G++VA ILSGIL++A P+ I FS Y LK +
Sbjct: 414 CYWWAVITMTTVGYGDMVPRSTPGQVVALSSILSGILLMAFPVTSIFHTFSRSYLELKQE 473
Query: 442 EAAVRQREA 450
+ V R A
Sbjct: 474 QERVMFRRA 482
>gi|27436996 potassium voltage-gated channel, subfamily G, member 4
[Homo sapiens]
Length = 519
Score = 277 bits (709), Expect = 1e-74
Identities = 169/469 (36%), Positives = 265/469 (56%), Gaps = 48/469 (10%)
Query: 8 LLDSPLDSGSLTSLDSSVFCSEG--EGEPLALGDCFTVNVGGSRFVLSQQALSCFPHTRL 65
LL SP+++ S+ L G + P+ L +NVGG R++L L FP +RL
Sbjct: 26 LLSSPMETPSIKGLYYRRVRKVGALDASPVDLKKEILINVGGRRYLLPWSTLDRFPLSRL 85
Query: 66 GKLAVVVASYRRPGALAAVPSPLELCDDANPVDNEYFFDRSSQAFRYVLHYYRTGRLHVM 125
KL + SY ++LCDD + E+FFDRS AF ++ + G+L ++
Sbjct: 86 SKLRLC-RSYEEI---------VQLCDDYDEDSQEFFFDRSPSAFGVIVSFLAAGKLVLL 135
Query: 126 EQLCALSFLQEIQYWGIDELSIDSCCRDRYFRR-KELSETLDFKKD---TEDQESQHESE 181
+++CALSF +E+ YWGI+E ++ CC + R+ +EL E ++ + +E++ +
Sbjct: 136 QEMCALSFQEELAYWGIEEAHLERCCLRKLLRKLEELEELAKLHREDVLRQQRETRRPAS 195
Query: 182 QDFSQGPCPTVRQKLWNILEKPGSSTAARIFGVISIIFVVVSIINMALMSAELSWLDLQL 241
G C +L ++E P S ++F +SI+FV + +++ + + DL+
Sbjct: 196 HSSRWGLC---MNRLREMVENPQSGLPGKVFACLSILFVATTAVSLCVSTMP----DLRA 248
Query: 242 LE-------------ILEYVCISWFTGEFVLRFLCVRDRCRFLRKVPNIIDLLAILPFYI 288
E I+E +C++WF+ EF LRF+ +D+C+F + NIID+LAI P+Y+
Sbjct: 249 EEDQGECSRKCYYIFIVETICVAWFSLEFCLRFVQAQDKCQFFQGPLNIIDILAISPYYV 308
Query: 289 TLLV--------ESLSGSQTTQELENVGRIVQVLRLLRALRMLKLGRHSTGLRSLGMTIT 340
+L V E SGS LE VG +++VLR LR L +++L RHS GL++LG+T+
Sbjct: 309 SLAVSEEPPEDGERPSGS---SYLEKVGLVLRVLRALRILYVMRLARHSLGLQTLGLTVR 365
Query: 341 QCYEEVGLLLLFLSVGISIFSTVEYFAE-QSIPDTTFTSVPCAWWWATTSMTTVGYGDIR 399
+C E GLLLLFL+V I++FS + Y AE +S FTS+P ++WWA SMTTVGYGD+
Sbjct: 366 RCTREFGLLLLFLAVAITLFSPLVYVAEKESGRVLEFTSIPASYWWAIISMTTVGYGDMV 425
Query: 400 PDTTTGKIVAFMCILSGILVLALPIAIINDRFSACYFTLKLKEAAVRQR 448
P + G++VA ILSGIL++A P I FS Y LK ++ ++ R
Sbjct: 426 PRSVPGQMVALSSILSGILIMAFPATSIFHTFSHSYLELKKEQEQLQAR 474
>gi|6912444 potassium voltage-gated channel, subfamily G, member 2
[Homo sapiens]
Length = 466
Score = 273 bits (697), Expect = 3e-73
Identities = 163/431 (37%), Positives = 250/431 (58%), Gaps = 26/431 (6%)
Query: 43 VNVGGSRFVLSQQALSCFPHTRLGKLAVVVASYRRPGALAAVPSPLELCDDANPVDNEYF 102
+NVGG R L+ AL+ P RL +L A L +CDD + +E+F
Sbjct: 21 INVGGCRVRLAWAALARCPLARLERLR----------ACRGHDDLLRVCDDYDVSRDEFF 70
Query: 103 FDRSSQAFRYVLHYYRTGRLHVMEQLCALSFLQEIQYWGIDELSIDSCCRDRYFRRKELS 162
FDRS AFR ++ R G+L ++ CAL+F E+ YWGIDE ++ CC R RR+E
Sbjct: 71 FDRSPCAFRAIVALLRAGKLRLLRGPCALAFRDELAYWGIDEARLERCCLRRLRRREE-- 128
Query: 163 ETLDFKKDTEDQESQHESEQDFS-QGPCPTVRQKLWNILEKPGSSTAARIFGVISIIFVV 221
E + + ++ +Q + +G R++L ++++ P S A ++F +S+ FV
Sbjct: 129 EAAEARAGPTERGAQGSPARALGPRGRLQRGRRRLRDVVDNPHSGLAGKLFACVSVSFVA 188
Query: 222 VSIINMALMS----------AELSWLDLQLLEILEYVCISWFTGEFVLRFLCVRDRCRFL 271
V+ + + L + E S + L +LE VC++WF+ EF+LR L +C FL
Sbjct: 189 VTAVGLCLSTMPDIRAEEERGECS-PKCRSLFVLETVCVAWFSFEFLLRSLQAESKCAFL 247
Query: 272 RKVPNIIDLLAILPFYITLLVESLSGSQTTQELENVGRIVQVLRLLRALRMLKLGRHSTG 331
R NIID+LA+LPFY++LL+ +G T+ LE G ++++LR LR L +++L RHS G
Sbjct: 248 RAPLNIIDILALLPFYVSLLLGLAAGPGGTKLLERAGLVLRLLRALRVLYVMRLARHSLG 307
Query: 332 LRSLGMTITQCYEEVGLLLLFLSVGISIFSTVEYFAEQSI-PDTTFTSVPCAWWWATTSM 390
LRSLG+T+ +C E GLLLLFL V +++F+ + + AE+ + F+SVP ++WWA SM
Sbjct: 308 LRSLGLTMRRCAREFGLLLLFLCVAMALFAPLVHLAERELGARRDFSSVPASYWWAVISM 367
Query: 391 TTVGYGDIRPDTTTGKIVAFMCILSGILVLALPIAIINDRFSACYFTLK-LKEAAVRQRE 449
TTVGYGD+ P + G++VA ILSGIL++A P+ I FS Y LK ++ A
Sbjct: 368 TTVGYGDMVPRSLPGQVVALSSILSGILLMAFPVTSIFHTFSRSYSELKEQQQRAASPEP 427
Query: 450 ALKKLTKNIAT 460
AL++ + + AT
Sbjct: 428 ALQEDSTHSAT 438
>gi|27436993 potassium voltage-gated channel, subfamily G, member 3
isoform 2 [Homo sapiens]
Length = 425
Score = 270 bits (690), Expect = 2e-72
Identities = 153/416 (36%), Positives = 243/416 (58%), Gaps = 30/416 (7%)
Query: 43 VNVGGSRFVLSQQALSCFPHTRLGKLAVVVASYRRPGALAAVPSPLELCDDANPVDNEYF 102
+NVGG+R+ LS++ L FP R+ +L + LE+CDD + NEYF
Sbjct: 13 LNVGGARYSLSRELLKDFPLRRVSRLH----------GCRSERDVLEVCDDYDRERNEYF 62
Query: 103 FDRSSQAFRYVLHYYRT-GRLHVMEQLCALSFLQEIQYWGIDELSIDSCCRDRYFRRKEL 161
FDR S+AF ++L Y R G+L ++C LSF E+ YWG++ ++ CC+ R R +
Sbjct: 63 FDRHSEAFGFILLYVRGHGKLRFAPRMCELSFYNEMIYWGLEGAHLEYCCQRRLDDR--M 120
Query: 162 SETLDFKKDTEDQESQHESEQDFSQGPCPTVR--QKLWNILEKPGSSTAARIFGVISIIF 219
S+T F E + + P+ R +++ E+P SS AA+I +S++F
Sbjct: 121 SDTYTFYSADEPGVLGRDEARPGGAEAAPSRRWLERMRRTFEEPTSSLAAQILASVSVVF 180
Query: 220 VVVSIINMALMSAELSW----LDLQLLE----ILEYVCISWFTGEFVLRFLCVRDRCRFL 271
V+VS++ + + W D + L+ I+E +CI WFT E ++RF+ +++C F+
Sbjct: 181 VIVSMVVLCASTLP-DWRNAAADNRSLDDRSRIIEAICIGWFTAECIVRFIVSKNKCEFV 239
Query: 272 RKVPNIIDLLAILPFYITLLVESLSGSQTTQELENVGRIVQVLRLLRALRMLKLGRHSTG 331
++ NIIDLLAI P+YI++L+ +G + +L+ G ++VLR++R ++KL RH G
Sbjct: 240 KRPLNIIDLLAITPYYISVLMTVFTGENS--QLQRAGVTLRVLRMMRIFWVIKLARHFIG 297
Query: 332 LRSLGMTITQCYEEVGLLLLFLSVGISIFSTVEYFAEQSIPDTT----FTSVPCAWWWAT 387
L++LG+T+ +CY E+ +LL+F+ V ++IFS + E + T FTS+P A WW
Sbjct: 298 LQTLGLTLKRCYREMVMLLVFICVAMAIFSALSQLLEHGLDLETSNKDFTSIPAACWWVI 357
Query: 388 TSMTTVGYGDIRPDTTTGKIVAFMCILSGILVLALPIAIINDRFSACYFTLKLKEA 443
SMTTVGYGD+ P T G+I+ +C++SGI++LALPI I F CY LK + A
Sbjct: 358 ISMTTVGYGDMYPITVPGRILGGVCVVSGIVLLALPITFIYHSFVQCYHELKFRSA 413
>gi|20070166 potassium voltage-gated channel, subfamily F, member 1
[Homo sapiens]
Length = 494
Score = 269 bits (687), Expect = 5e-72
Identities = 153/423 (36%), Positives = 236/423 (55%), Gaps = 22/423 (5%)
Query: 43 VNVGGSRFVLSQQALSCFPHTRLGKLAVVVASYRRPGALAAVPSPLELCDDANPVDNEYF 102
VNVGG R VL LS +P TRL +L +A + LCDD +P E++
Sbjct: 27 VNVGGVRQVLYGDLLSQYPETRLAELINCLAG--------GYDTIFSLCDDYDPGKREFY 78
Query: 103 FDRSSQAFRYVLHYYRTGRLHVMEQLCALSFLQEIQYWGIDELSIDSCCRDRYFRRKELS 162
FDR AF+ V+ Y G +H+ + +C + F E+ +W +D +D CC+ ++E
Sbjct: 79 FDRDPDAFKCVIEVYYFGEVHMKKGICPICFKNEMDFWKVDLKFLDDCCKSHLSEKREEL 138
Query: 163 ETLDFKKDTEDQESQHESEQDFSQGPCPTVRQKLWNILEKPGSSTAARIFGVISIIFVVV 222
E + + Q + D ++G ++ +W LEKP SS AR+ V+S + ++V
Sbjct: 139 EEIARRV----QLILDDLGVDAAEGRWRRCQKCVWKFLEKPESSCPARVVAVLSFLLILV 194
Query: 223 SIINMAL--------MSAELSWLDLQLLEILEYVCISWFTGEFVLRFLCVRDRCRFLRKV 274
S + M + + AE + ++ LE +E CI WFT E++LR ++ F
Sbjct: 195 SSVVMCMGTIPELQVLDAEGNRVEHPTLENVETACIGWFTLEYLLRLFSSPNKLHFALSF 254
Query: 275 PNIIDLLAILPFYITLLVESLSGSQTTQELENVGRIVQVLRLLRALRMLKLGRHSTGLRS 334
NI+D+LAILPFY++L + L EL NV + VQ LR++R R+ KL RHS+GL++
Sbjct: 255 MNIVDVLAILPFYVSLTLTHLGARM--MELTNVQQAVQALRIMRIARIFKLARHSSGLQT 312
Query: 335 LGMTITQCYEEVGLLLLFLSVGISIFSTVEYFAEQSIPDTTFTSVPCAWWWATTSMTTVG 394
L + + ++E+GLLL++L+VGI +FS + Y EQS P+T F S+P ++WWA +MTTVG
Sbjct: 313 LTYALKRSFKELGLLLMYLAVGIFVFSALGYTMEQSHPETLFKSIPQSFWWAIITMTTVG 372
Query: 395 YGDIRPDTTTGKIVAFMCILSGILVLALPIAIINDRFSACYFTLKLKEAAVRQREALKKL 454
YGDI P TT GK+ A + L G++ +ALPI I + F Y ++ E A + L +L
Sbjct: 373 YGDIYPKTTLGKLNAAISFLCGVIAIALPIHPIINNFVRYYNKQRVLETAAKHELELMEL 432
Query: 455 TKN 457
+
Sbjct: 433 NSS 435
>gi|19071574 potassium voltage-gated channel, subfamily G, member 3
isoform 1 [Homo sapiens]
Length = 436
Score = 266 bits (679), Expect = 4e-71
Identities = 153/427 (35%), Positives = 243/427 (56%), Gaps = 41/427 (9%)
Query: 43 VNVGGSRFVLSQQALSCFPHTRLGKLAVVVASYRRPGALAAVPSPLELCDDANPVDNEYF 102
+NVGG+R+ LS++ L FP R+ +L + LE+CDD + NEYF
Sbjct: 13 LNVGGARYSLSRELLKDFPLRRVSRLH----------GCRSERDVLEVCDDYDRERNEYF 62
Query: 103 FDRSSQAFRYVLHYYRT-GRLHVMEQLCALSFLQEIQYWGIDELSIDSCCRDRYFRRKEL 161
FDR S+AF ++L Y R G+L ++C LSF E+ YWG++ ++ CC+ R R +
Sbjct: 63 FDRHSEAFGFILLYVRGHGKLRFAPRMCELSFYNEMIYWGLEGAHLEYCCQRRLDDR--M 120
Query: 162 SETLDFKKDTEDQESQHESEQDFSQGPCPTVR--QKLWNILEKPGSSTAARIFGVISIIF 219
S+T F E + + P+ R +++ E+P SS AA+I +S++F
Sbjct: 121 SDTYTFYSADEPGVLGRDEARPGGAEAAPSRRWLERMRRTFEEPTSSLAAQILASVSVVF 180
Query: 220 VVVSIINMALMSAELSW----LDLQLLE---------------ILEYVCISWFTGEFVLR 260
V+VS++ + + W D + L+ I+E +CI WFT E ++R
Sbjct: 181 VIVSMVVLCASTLP-DWRNAAADNRSLDDRSRYSAGPGREPSGIIEAICIGWFTAECIVR 239
Query: 261 FLCVRDRCRFLRKVPNIIDLLAILPFYITLLVESLSGSQTTQELENVGRIVQVLRLLRAL 320
F+ +++C F+++ NIIDLLAI P+YI++L+ +G + +L+ G ++VLR++R
Sbjct: 240 FIVSKNKCEFVKRPLNIIDLLAITPYYISVLMTVFTGENS--QLQRAGVTLRVLRMMRIF 297
Query: 321 RMLKLGRHSTGLRSLGMTITQCYEEVGLLLLFLSVGISIFSTVEYFAEQSIPDTT----F 376
++KL RH GL++LG+T+ +CY E+ +LL+F+ V ++IFS + E + T F
Sbjct: 298 WVIKLARHFIGLQTLGLTLKRCYREMVMLLVFICVAMAIFSALSQLLEHGLDLETSNKDF 357
Query: 377 TSVPCAWWWATTSMTTVGYGDIRPDTTTGKIVAFMCILSGILVLALPIAIINDRFSACYF 436
TS+P A WW SMTTVGYGD+ P T G+I+ +C++SGI++LALPI I F CY
Sbjct: 358 TSIPAACWWVIISMTTVGYGDMYPITVPGRILGGVCVVSGIVLLALPITFIYHSFVQCYH 417
Query: 437 TLKLKEA 443
LK + A
Sbjct: 418 ELKFRSA 424
>gi|27436981 potassium voltage-gated channel, Shal-related
subfamily, member 1 [Homo sapiens]
Length = 647
Score = 251 bits (640), Expect = 1e-66
Identities = 162/450 (36%), Positives = 236/450 (52%), Gaps = 66/450 (14%)
Query: 39 DCFTVNVGGSRFVLSQQALSCFPHTRLGKLAVVVASYRRPGALAAVPSPLELCDDANPVD 98
+ VNV G RF + L +P T LG S E DA+
Sbjct: 40 EVLVVNVSGRRFETWKNTLDRYPDTLLGS------------------SEKEFFYDAD--S 79
Query: 99 NEYFFDRSSQAFRYVLHYYRTGRLHVMEQLCALSFLQEIQYWGIDELSIDSCCRDRYF-R 157
EYFFDR FR+VL++YRTGRLH Q C +F +E+ ++G+ + CC + Y R
Sbjct: 80 GEYFFDRDPDMFRHVLNFYRTGRLHCPRQECIQAFDEELAFYGLVPELVGDCCLEEYRDR 139
Query: 158 RKELSETLDFKKDTEDQESQHESEQDFSQGPC----PTVRQKLWNILEKPGSSTAARIFG 213
+KE +E L ED+E++ + GP ++RQ+LW E P +STAA +F
Sbjct: 140 KKENAERL-----AEDEEAEQAGD-----GPALPAGSSLRQRLWRAFENPHTSTAALVFY 189
Query: 214 VISIIFVVVSIINMALM------SAELSWLDL-------QLLEILEYVCISWFTGEFVLR 260
++ F+ VS+I + SA S + Q ++ C+ FTGE++LR
Sbjct: 190 YVTGFFIAVSVIANVVETIPCRGSARRSSREQPCGERFPQAFFCMDTACVLIFTGEYLLR 249
Query: 261 FLCVRDRCRFLRKVPNIIDLLAILPFYITLLV---ESLSGSQTTQELENVGRIVQVLRLL 317
RCRFLR V ++ID++AILP+YI LLV + +SG+ T LR+
Sbjct: 250 LFAAPSRCRFLRSVMSLIDVVAILPYYIGLLVPKNDDVSGAFVT------------LRVF 297
Query: 318 RALRMLKLGRHSTGLRSLGMTITQCYEEVGLLLLFLSVGISIFSTVEYFAEQSIPDTTFT 377
R R+ K RHS GLR LG T+ C E+G LL L++ I IF+TV ++AE+ T FT
Sbjct: 298 RVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGTNKTNFT 357
Query: 378 SVPCAWWWATTSMTTVGYGDIRPDTTTGKIVAFMCILSGILVLALPIAIINDRFSACYF- 436
S+P A+W+ +MTT+GYGD+ P T GKI +C LSG+LV+ALP+ +I FS Y
Sbjct: 358 SIPAAFWYTIVTMTTLGYGDMVPSTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQ 417
Query: 437 --TLKLKEAAVRQREALKKLTKNIATDSYI 464
+ A + R A +L K+ T++++
Sbjct: 418 NQRADKRRAQQKVRLARIRLAKSGTTNAFL 447
>gi|88758576 Shaw-related voltage-gated potassium channel protein 4
isoform c [Homo sapiens]
Length = 626
Score = 240 bits (612), Expect = 2e-63
Identities = 154/475 (32%), Positives = 235/475 (49%), Gaps = 66/475 (13%)
Query: 33 EPLALGDC---FTVNVGGSRFVLSQQALSCFPHTRLGKLAVVVASYRRPGALAAVPSPLE 89
E +A G+ +NVGG+R + L P TRL LA R V S
Sbjct: 27 EEMAKGEASEKIIINVGGTRHETYRSTLRTLPGTRLAWLADPDGGGRPETDGGGVGSS-- 84
Query: 90 LCDDANPVDNEYFFDRSSQAFRYVLHYYRTGRLHVMEQLCALSFLQEIQYWGIDELSIDS 149
+ E+FFDR F YVL+YYRTG+LH +C F +E+ +WGIDE ++
Sbjct: 85 --GSSGGGGCEFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELTFWGIDETDVEP 142
Query: 150 CCRDRYFRRKELSETLDFKKDTE---------DQESQHESE--------------QDFSQ 186
CC Y + ++ E LD + + D+ E E
Sbjct: 143 CCWMTYRQHRDAEEALDIFESPDGGGSGAGPSDEAGDDERELALQRLGPHEGGAGHGAGS 202
Query: 187 GPCPTVRQKLWNILEKPGSSTAARIFGVISIIFVVVSIINMALMSAELSWLDLQLLEIL- 245
G C + ++W + E P SS AAR+ S+ F++VSI L + E +D + EIL
Sbjct: 203 GGCRGWQPRMWALFEDPYSSRAARVVAFASLFFILVSITTFCLETHEAFNIDRNVTEILR 262
Query: 246 ----------------------EYVCISWFTGEFVLRFLCVRDRCRFLRKVPNIIDLLAI 283
E VC+ WFT EF++R +C D F++ + NIID +AI
Sbjct: 263 VGNITSVHFRREVETEPILTYIEGVCVLWFTLEFLVRIVCCPDTLDFVKNLLNIIDFVAI 322
Query: 284 LPFYITLLVESLSGSQTTQELENVGRIVQVLRLLRALRMLKLGRHSTGLRSLGMTITQCY 343
LPFY+ + + LS ++ +V ++V+R +R LR+ KL RH GLR LG T+
Sbjct: 323 LPFYLEVGLSGLS----SKAARDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRAST 378
Query: 344 EEVGLLLLFLSVGISIFSTVEYFAEQ-----SIP----DTTFTSVPCAWWWATTSMTTVG 394
E LL++FL++G+ IF+T+ Y+AE+ S P T F ++P +WWA +MTT+G
Sbjct: 379 NEFLLLIIFLALGVLIFATMIYYAERIGARPSDPRGNDHTDFKNIPIGFWWAVVTMTTLG 438
Query: 395 YGDIRPDTTTGKIVAFMCILSGILVLALPIAIINDRFSACYFTLKLKEAAVRQRE 449
YGD+ P T +G +V +C L+G+L +A+P+ +I + F Y K+ ++R+
Sbjct: 439 YGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKRK 493
>gi|24497462 Shaw-related voltage-gated potassium channel protein 4
isoform a [Homo sapiens]
Length = 635
Score = 240 bits (612), Expect = 2e-63
Identities = 154/475 (32%), Positives = 235/475 (49%), Gaps = 66/475 (13%)
Query: 33 EPLALGDC---FTVNVGGSRFVLSQQALSCFPHTRLGKLAVVVASYRRPGALAAVPSPLE 89
E +A G+ +NVGG+R + L P TRL LA R V S
Sbjct: 27 EEMAKGEASEKIIINVGGTRHETYRSTLRTLPGTRLAWLADPDGGGRPETDGGGVGSS-- 84
Query: 90 LCDDANPVDNEYFFDRSSQAFRYVLHYYRTGRLHVMEQLCALSFLQEIQYWGIDELSIDS 149
+ E+FFDR F YVL+YYRTG+LH +C F +E+ +WGIDE ++
Sbjct: 85 --GSSGGGGCEFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELTFWGIDETDVEP 142
Query: 150 CCRDRYFRRKELSETLDFKKDTE---------DQESQHESE--------------QDFSQ 186
CC Y + ++ E LD + + D+ E E
Sbjct: 143 CCWMTYRQHRDAEEALDIFESPDGGGSGAGPSDEAGDDERELALQRLGPHEGGAGHGAGS 202
Query: 187 GPCPTVRQKLWNILEKPGSSTAARIFGVISIIFVVVSIINMALMSAELSWLDLQLLEIL- 245
G C + ++W + E P SS AAR+ S+ F++VSI L + E +D + EIL
Sbjct: 203 GGCRGWQPRMWALFEDPYSSRAARVVAFASLFFILVSITTFCLETHEAFNIDRNVTEILR 262
Query: 246 ----------------------EYVCISWFTGEFVLRFLCVRDRCRFLRKVPNIIDLLAI 283
E VC+ WFT EF++R +C D F++ + NIID +AI
Sbjct: 263 VGNITSVHFRREVETEPILTYIEGVCVLWFTLEFLVRIVCCPDTLDFVKNLLNIIDFVAI 322
Query: 284 LPFYITLLVESLSGSQTTQELENVGRIVQVLRLLRALRMLKLGRHSTGLRSLGMTITQCY 343
LPFY+ + + LS ++ +V ++V+R +R LR+ KL RH GLR LG T+
Sbjct: 323 LPFYLEVGLSGLS----SKAARDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRAST 378
Query: 344 EEVGLLLLFLSVGISIFSTVEYFAEQ-----SIP----DTTFTSVPCAWWWATTSMTTVG 394
E LL++FL++G+ IF+T+ Y+AE+ S P T F ++P +WWA +MTT+G
Sbjct: 379 NEFLLLIIFLALGVLIFATMIYYAERIGARPSDPRGNDHTDFKNIPIGFWWAVVTMTTLG 438
Query: 395 YGDIRPDTTTGKIVAFMCILSGILVLALPIAIINDRFSACYFTLKLKEAAVRQRE 449
YGD+ P T +G +V +C L+G+L +A+P+ +I + F Y K+ ++R+
Sbjct: 439 YGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKRK 493
>gi|24497464 Shaw-related voltage-gated potassium channel protein 4
isoform b [Homo sapiens]
Length = 582
Score = 240 bits (612), Expect = 2e-63
Identities = 154/475 (32%), Positives = 235/475 (49%), Gaps = 66/475 (13%)
Query: 33 EPLALGDC---FTVNVGGSRFVLSQQALSCFPHTRLGKLAVVVASYRRPGALAAVPSPLE 89
E +A G+ +NVGG+R + L P TRL LA R V S
Sbjct: 27 EEMAKGEASEKIIINVGGTRHETYRSTLRTLPGTRLAWLADPDGGGRPETDGGGVGSS-- 84
Query: 90 LCDDANPVDNEYFFDRSSQAFRYVLHYYRTGRLHVMEQLCALSFLQEIQYWGIDELSIDS 149
+ E+FFDR F YVL+YYRTG+LH +C F +E+ +WGIDE ++
Sbjct: 85 --GSSGGGGCEFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELTFWGIDETDVEP 142
Query: 150 CCRDRYFRRKELSETLDFKKDTE---------DQESQHESE--------------QDFSQ 186
CC Y + ++ E LD + + D+ E E
Sbjct: 143 CCWMTYRQHRDAEEALDIFESPDGGGSGAGPSDEAGDDERELALQRLGPHEGGAGHGAGS 202
Query: 187 GPCPTVRQKLWNILEKPGSSTAARIFGVISIIFVVVSIINMALMSAELSWLDLQLLEIL- 245
G C + ++W + E P SS AAR+ S+ F++VSI L + E +D + EIL
Sbjct: 203 GGCRGWQPRMWALFEDPYSSRAARVVAFASLFFILVSITTFCLETHEAFNIDRNVTEILR 262
Query: 246 ----------------------EYVCISWFTGEFVLRFLCVRDRCRFLRKVPNIIDLLAI 283
E VC+ WFT EF++R +C D F++ + NIID +AI
Sbjct: 263 VGNITSVHFRREVETEPILTYIEGVCVLWFTLEFLVRIVCCPDTLDFVKNLLNIIDFVAI 322
Query: 284 LPFYITLLVESLSGSQTTQELENVGRIVQVLRLLRALRMLKLGRHSTGLRSLGMTITQCY 343
LPFY+ + + LS ++ +V ++V+R +R LR+ KL RH GLR LG T+
Sbjct: 323 LPFYLEVGLSGLS----SKAARDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRAST 378
Query: 344 EEVGLLLLFLSVGISIFSTVEYFAEQ-----SIP----DTTFTSVPCAWWWATTSMTTVG 394
E LL++FL++G+ IF+T+ Y+AE+ S P T F ++P +WWA +MTT+G
Sbjct: 379 NEFLLLIIFLALGVLIFATMIYYAERIGARPSDPRGNDHTDFKNIPIGFWWAVVTMTTLG 438
Query: 395 YGDIRPDTTTGKIVAFMCILSGILVLALPIAIINDRFSACYFTLKLKEAAVRQRE 449
YGD+ P T +G +V +C L+G+L +A+P+ +I + F Y K+ ++R+
Sbjct: 439 YGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKRK 493
>gi|9789987 potassium voltage-gated channel, Shal-related subfamily,
member 2 [Homo sapiens]
Length = 630
Score = 231 bits (590), Expect = 9e-61
Identities = 143/421 (33%), Positives = 217/421 (51%), Gaps = 50/421 (11%)
Query: 43 VNVGGSRFVLSQQALSCFPHTRLGKLAVVVASYRRPGALAAVPSPLELCDDANPVDNEYF 102
+NV G+RF Q L +P T LG E +P +YF
Sbjct: 45 LNVSGTRFQTWQDTLERYPDTLLGSS--------------------ERDFFYHPETQQYF 84
Query: 103 FDRSSQAFRYVLHYYRTGRLHVMEQLCALSFLQEIQYWGIDELSIDSCCRDRYF-RRKEL 161
FDR FR++L++YRTG+LH C ++ +E+ ++G+ I CC + Y RR+E
Sbjct: 85 FDRDPDIFRHILNFYRTGKLHYPRHECISAYDEELAFFGLIPEIIGDCCYEEYKDRRREN 144
Query: 162 SETLDFKKDTEDQESQHESEQDFSQGPCPTVRQKLWNILEKPGSSTAARIFGVISIIFVV 221
+E L +D D ++ ES P T RQ++W E P +ST A +F ++ F+
Sbjct: 145 AERL---QDDADTDTAGESAL-----PTMTARQRVWRAFENPHTSTMALVFYYVTGFFIA 196
Query: 222 VSIINMALMSAELSWLDLQLLEI------------LEYVCISWFTGEFVLRFLCVRDRCR 269
VS+I + + + E+ L+ C+ FT E++LR R R
Sbjct: 197 VSVIANVVETVPCGSSPGHIKELPCGERYAVAFFCLDTACVMIFTVEYLLRLAAAPSRYR 256
Query: 270 FLRKVPNIIDLLAILPFYITLLVESLSGSQTTQELENVGRIVQVLRLLRALRMLKLGRHS 329
F+R V +IID++AILP+YI L++ + E+V LR+ R R+ K RHS
Sbjct: 257 FVRSVMSIIDVVAILPYYIGLVMT---------DNEDVSGAFVTLRVFRVFRIFKFSRHS 307
Query: 330 TGLRSLGMTITQCYEEVGLLLLFLSVGISIFSTVEYFAEQSIPDTTFTSVPCAWWWATTS 389
GLR LG T+ C E+G LL L++ I IF+TV ++AE+ + FTS+P A+W+ +
Sbjct: 308 QGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPAAFWYTIVT 367
Query: 390 MTTVGYGDIRPDTTTGKIVAFMCILSGILVLALPIAIINDRFSACYFTLKLKEAAVRQRE 449
MTT+GYGD+ P T GKI +C LSG+LV+ALP+ +I FS Y + + Q++
Sbjct: 368 MTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRRAQKK 427
Query: 450 A 450
A
Sbjct: 428 A 428
>gi|21217561 Shaw-related voltage-gated potassium channel protein 2
isoform KV3.2a [Homo sapiens]
Length = 613
Score = 229 bits (585), Expect = 3e-60
Identities = 153/491 (31%), Positives = 238/491 (48%), Gaps = 92/491 (18%)
Query: 43 VNVGGSRFVLSQQALSCFPHTRLGKLAVVVASYRRPG--------ALAAVPSPLELCDDA 94
+NVGG+R + L P TRL LA S PG L P PL A
Sbjct: 12 LNVGGTRHETYRSTLKTLPGTRLALLA----SSEPPGDCLTTAGDKLQPSPPPLSPPPRA 67
Query: 95 NPVD----------------------------NEYFFDRSSQAFRYVLHYYRTGRLHVME 126
P+ E+FFDR F YVL+YYRTG+LH
Sbjct: 68 PPLSPGPGGCFEGGAGNCSSRGGRASDHPGGGREFFFDRHPGVFAYVLNYYRTGKLHCPA 127
Query: 127 QLCALSFLQEIQYWGIDELSIDSCCRDRYFRRKELSETLDFKK----------DTEDQES 176
+C F +E+ +WGIDE ++ CC Y + ++ E LD + D ED +
Sbjct: 128 DVCGPLFEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDIFETPDLIGGDPGDDEDLAA 187
Query: 177 QHESEQDFS--------QGPCPTVRQKLWNILEKPGSSTAARIFGVISIIFVVVSIINMA 228
+ +D + G ++ ++W + E P SS AAR S+ F++VSI
Sbjct: 188 KRLGIEDAAGLGGPDGKSGRWRRLQPRMWALFEDPYSSRAARFIAFASLFFILVSITTFC 247
Query: 229 LMSAEL--------------SWLDLQ-------LLEILEYVCISWFTGEFVLRFLCVRDR 267
L + E + + LQ L +E VC+ WFT EF++R + ++
Sbjct: 248 LETHEAFNIVKNKTEPVINGTSVVLQYEIETDPALTYVEGVCVVWFTFEFLVRIVFSPNK 307
Query: 268 CRFLRKVPNIIDLLAILPFYITLLVESLSGSQTTQELENVGRIVQVLRLLRALRMLKLGR 327
F++ + NIID +AILPFY+ + + LS ++ ++V ++V+R +R LR+ KL R
Sbjct: 308 LEFIKNLLNIIDFVAILPFYLEVGLSGLS----SKAAKDVLGFLRVVRFVRILRIFKLTR 363
Query: 328 HSTGLRSLGMTITQCYEEVGLLLLFLSVGISIFSTVEYFAEQ---------SIPDTTFTS 378
H GLR LG T+ E LL++FL++G+ IF+T+ Y+AE+ + T F +
Sbjct: 364 HFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKN 423
Query: 379 VPCAWWWATTSMTTVGYGDIRPDTTTGKIVAFMCILSGILVLALPIAIINDRFSACYFTL 438
+P +WWA +MTT+GYGD+ P T +G +V +C L+G+L +A+P+ +I + F Y
Sbjct: 424 IPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLA 483
Query: 439 KLKEAAVRQRE 449
K+ R+R+
Sbjct: 484 MAKQKLPRKRK 494
>gi|21217563 Shaw-related voltage-gated potassium channel protein 2
isoform KV3.2b [Homo sapiens]
Length = 638
Score = 229 bits (585), Expect = 3e-60
Identities = 153/491 (31%), Positives = 238/491 (48%), Gaps = 92/491 (18%)
Query: 43 VNVGGSRFVLSQQALSCFPHTRLGKLAVVVASYRRPG--------ALAAVPSPLELCDDA 94
+NVGG+R + L P TRL LA S PG L P PL A
Sbjct: 12 LNVGGTRHETYRSTLKTLPGTRLALLA----SSEPPGDCLTTAGDKLQPSPPPLSPPPRA 67
Query: 95 NPVD----------------------------NEYFFDRSSQAFRYVLHYYRTGRLHVME 126
P+ E+FFDR F YVL+YYRTG+LH
Sbjct: 68 PPLSPGPGGCFEGGAGNCSSRGGRASDHPGGGREFFFDRHPGVFAYVLNYYRTGKLHCPA 127
Query: 127 QLCALSFLQEIQYWGIDELSIDSCCRDRYFRRKELSETLDFKK----------DTEDQES 176
+C F +E+ +WGIDE ++ CC Y + ++ E LD + D ED +
Sbjct: 128 DVCGPLFEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDIFETPDLIGGDPGDDEDLAA 187
Query: 177 QHESEQDFS--------QGPCPTVRQKLWNILEKPGSSTAARIFGVISIIFVVVSIINMA 228
+ +D + G ++ ++W + E P SS AAR S+ F++VSI
Sbjct: 188 KRLGIEDAAGLGGPDGKSGRWRRLQPRMWALFEDPYSSRAARFIAFASLFFILVSITTFC 247
Query: 229 LMSAEL--------------SWLDLQ-------LLEILEYVCISWFTGEFVLRFLCVRDR 267
L + E + + LQ L +E VC+ WFT EF++R + ++
Sbjct: 248 LETHEAFNIVKNKTEPVINGTSVVLQYEIETDPALTYVEGVCVVWFTFEFLVRIVFSPNK 307
Query: 268 CRFLRKVPNIIDLLAILPFYITLLVESLSGSQTTQELENVGRIVQVLRLLRALRMLKLGR 327
F++ + NIID +AILPFY+ + + LS ++ ++V ++V+R +R LR+ KL R
Sbjct: 308 LEFIKNLLNIIDFVAILPFYLEVGLSGLS----SKAAKDVLGFLRVVRFVRILRIFKLTR 363
Query: 328 HSTGLRSLGMTITQCYEEVGLLLLFLSVGISIFSTVEYFAEQ---------SIPDTTFTS 378
H GLR LG T+ E LL++FL++G+ IF+T+ Y+AE+ + T F +
Sbjct: 364 HFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKN 423
Query: 379 VPCAWWWATTSMTTVGYGDIRPDTTTGKIVAFMCILSGILVLALPIAIINDRFSACYFTL 438
+P +WWA +MTT+GYGD+ P T +G +V +C L+G+L +A+P+ +I + F Y
Sbjct: 424 IPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLA 483
Query: 439 KLKEAAVRQRE 449
K+ R+R+
Sbjct: 484 MAKQKLPRKRK 494
>gi|24497458 Shaw-related voltage-gated potassium channel protein 2
isoform KV3.2c [Homo sapiens]
Length = 558
Score = 229 bits (585), Expect = 3e-60
Identities = 153/491 (31%), Positives = 238/491 (48%), Gaps = 92/491 (18%)
Query: 43 VNVGGSRFVLSQQALSCFPHTRLGKLAVVVASYRRPG--------ALAAVPSPLELCDDA 94
+NVGG+R + L P TRL LA S PG L P PL A
Sbjct: 12 LNVGGTRHETYRSTLKTLPGTRLALLA----SSEPPGDCLTTAGDKLQPSPPPLSPPPRA 67
Query: 95 NPVD----------------------------NEYFFDRSSQAFRYVLHYYRTGRLHVME 126
P+ E+FFDR F YVL+YYRTG+LH
Sbjct: 68 PPLSPGPGGCFEGGAGNCSSRGGRASDHPGGGREFFFDRHPGVFAYVLNYYRTGKLHCPA 127
Query: 127 QLCALSFLQEIQYWGIDELSIDSCCRDRYFRRKELSETLDFKK----------DTEDQES 176
+C F +E+ +WGIDE ++ CC Y + ++ E LD + D ED +
Sbjct: 128 DVCGPLFEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDIFETPDLIGGDPGDDEDLAA 187
Query: 177 QHESEQDFS--------QGPCPTVRQKLWNILEKPGSSTAARIFGVISIIFVVVSIINMA 228
+ +D + G ++ ++W + E P SS AAR S+ F++VSI
Sbjct: 188 KRLGIEDAAGLGGPDGKSGRWRRLQPRMWALFEDPYSSRAARFIAFASLFFILVSITTFC 247
Query: 229 LMSAEL--------------SWLDLQ-------LLEILEYVCISWFTGEFVLRFLCVRDR 267
L + E + + LQ L +E VC+ WFT EF++R + ++
Sbjct: 248 LETHEAFNIVKNKTEPVINGTSVVLQYEIETDPALTYVEGVCVVWFTFEFLVRIVFSPNK 307
Query: 268 CRFLRKVPNIIDLLAILPFYITLLVESLSGSQTTQELENVGRIVQVLRLLRALRMLKLGR 327
F++ + NIID +AILPFY+ + + LS ++ ++V ++V+R +R LR+ KL R
Sbjct: 308 LEFIKNLLNIIDFVAILPFYLEVGLSGLS----SKAAKDVLGFLRVVRFVRILRIFKLTR 363
Query: 328 HSTGLRSLGMTITQCYEEVGLLLLFLSVGISIFSTVEYFAEQ---------SIPDTTFTS 378
H GLR LG T+ E LL++FL++G+ IF+T+ Y+AE+ + T F +
Sbjct: 364 HFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKN 423
Query: 379 VPCAWWWATTSMTTVGYGDIRPDTTTGKIVAFMCILSGILVLALPIAIINDRFSACYFTL 438
+P +WWA +MTT+GYGD+ P T +G +V +C L+G+L +A+P+ +I + F Y
Sbjct: 424 IPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLA 483
Query: 439 KLKEAAVRQRE 449
K+ R+R+
Sbjct: 484 MAKQKLPRKRK 494
>gi|27436984 potassium voltage-gated channel, Shal-related
subfamily, member 3 isoform 1 [Homo sapiens]
Length = 655
Score = 226 bits (575), Expect = 5e-59
Identities = 147/443 (33%), Positives = 221/443 (49%), Gaps = 57/443 (12%)
Query: 39 DCFTVNVGGSRFVLSQQALSCFPHTRLGKLAVVVASYRRPGALAAVPSPLELCDDANPVD 98
+ +NV G RF + L +P T LG E N
Sbjct: 40 ELIVLNVSGRRFQTWRTTLERYPDTLLGST--------------------EKEFFFNEDT 79
Query: 99 NEYFFDRSSQAFRYVLHYYRTGRLHVMEQLCALSFLQEIQYWGIDELSIDSCCRDRYFRR 158
EYFFDR + FR VL++YRTG+LH C ++ E+ ++GI I CC + Y R
Sbjct: 80 KEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAFYGILPEIIGDCCYEEYKDR 139
Query: 159 KELSETLDFKKDTEDQESQHESEQDFSQGPCPTVRQKLWNILEKPGSSTAARIFGVISII 218
K E + D D E+ ES P + RQ +W E P +ST A +F ++
Sbjct: 140 KR--ENAERLMDDNDSENNQESM------PSLSFRQTMWRAFENPHTSTLALVFYYVTGF 191
Query: 219 FVVVSIINMALMSAELSWL----DLQLLE-------ILEYVCISWFTGEFVLRFLCVRDR 267
F+ VS+I + + + +L E L+ C+ FT E++LR R
Sbjct: 192 FIAVSVITNVVETVPCGTVPGSKELPCGERYSVAFFCLDTACVMIFTVEYLLRLFAAPSR 251
Query: 268 CRFLRKVPNIIDLLAILPFYITLLV---ESLSGSQTTQELENVGRIVQVLRLLRALRMLK 324
RF+R V +IID++AI+P+YI L++ E +SG+ T LR+ R R+ K
Sbjct: 252 YRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFVT------------LRVFRVFRIFK 299
Query: 325 LGRHSTGLRSLGMTITQCYEEVGLLLLFLSVGISIFSTVEYFAEQSIPDTTFTSVPCAWW 384
RHS GLR LG T+ C E+G LL L++ I IF+TV ++AE+ + FTS+P ++W
Sbjct: 300 FSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPASFW 359
Query: 385 WATTSMTTVGYGDIRPDTTTGKIVAFMCILSGILVLALPIAIINDRFSACYF---TLKLK 441
+ +MTT+GYGD+ P T GKI +C LSG+LV+ALP+ +I FS Y +
Sbjct: 360 YTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKR 419
Query: 442 EAAVRQREALKKLTKNIATDSYI 464
A + R A ++ K ++++Y+
Sbjct: 420 RAQKKARLARIRVAKTGSSNAYL 442
>gi|27436986 potassium voltage-gated channel, Shal-related
subfamily, member 3 isoform 2 [Homo sapiens]
Length = 636
Score = 226 bits (575), Expect = 5e-59
Identities = 147/443 (33%), Positives = 221/443 (49%), Gaps = 57/443 (12%)
Query: 39 DCFTVNVGGSRFVLSQQALSCFPHTRLGKLAVVVASYRRPGALAAVPSPLELCDDANPVD 98
+ +NV G RF + L +P T LG E N
Sbjct: 40 ELIVLNVSGRRFQTWRTTLERYPDTLLGST--------------------EKEFFFNEDT 79
Query: 99 NEYFFDRSSQAFRYVLHYYRTGRLHVMEQLCALSFLQEIQYWGIDELSIDSCCRDRYFRR 158
EYFFDR + FR VL++YRTG+LH C ++ E+ ++GI I CC + Y R
Sbjct: 80 KEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAFYGILPEIIGDCCYEEYKDR 139
Query: 159 KELSETLDFKKDTEDQESQHESEQDFSQGPCPTVRQKLWNILEKPGSSTAARIFGVISII 218
K E + D D E+ ES P + RQ +W E P +ST A +F ++
Sbjct: 140 KR--ENAERLMDDNDSENNQESM------PSLSFRQTMWRAFENPHTSTLALVFYYVTGF 191
Query: 219 FVVVSIINMALMSAELSWL----DLQLLE-------ILEYVCISWFTGEFVLRFLCVRDR 267
F+ VS+I + + + +L E L+ C+ FT E++LR R
Sbjct: 192 FIAVSVITNVVETVPCGTVPGSKELPCGERYSVAFFCLDTACVMIFTVEYLLRLFAAPSR 251
Query: 268 CRFLRKVPNIIDLLAILPFYITLLV---ESLSGSQTTQELENVGRIVQVLRLLRALRMLK 324
RF+R V +IID++AI+P+YI L++ E +SG+ T LR+ R R+ K
Sbjct: 252 YRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFVT------------LRVFRVFRIFK 299
Query: 325 LGRHSTGLRSLGMTITQCYEEVGLLLLFLSVGISIFSTVEYFAEQSIPDTTFTSVPCAWW 384
RHS GLR LG T+ C E+G LL L++ I IF+TV ++AE+ + FTS+P ++W
Sbjct: 300 FSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPASFW 359
Query: 385 WATTSMTTVGYGDIRPDTTTGKIVAFMCILSGILVLALPIAIINDRFSACYF---TLKLK 441
+ +MTT+GYGD+ P T GKI +C LSG+LV+ALP+ +I FS Y +
Sbjct: 360 YTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKR 419
Query: 442 EAAVRQREALKKLTKNIATDSYI 464
A + R A ++ K ++++Y+
Sbjct: 420 RAQKKARLARIRVAKTGSSNAYL 442
>gi|4826786 Shaw-related voltage-gated potassium channel protein 1
isoform B [Homo sapiens]
Length = 511
Score = 224 bits (571), Expect = 1e-58
Identities = 141/465 (30%), Positives = 232/465 (49%), Gaps = 77/465 (16%)
Query: 43 VNVGGSRFVLSQQALSCFPHTRLGKLAVVVASYRRPGALAAVPSPLELCDDANPVDNEYF 102
+NVGG+R + L P TRL LA P A + D +P +E+F
Sbjct: 12 INVGGTRHQTYRSTLRTLPGTRLAWLA-------EPDAHSHF--------DYDPRADEFF 56
Query: 103 FDRSSQAFRYVLHYYRTGRLHVMEQLCALSFLQEIQYWGIDELSIDSCCRDRYFRRKELS 162
FDR F ++L+YYRTG+LH +C + +E+ +WGIDE ++ CC Y + ++
Sbjct: 57 FDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAE 116
Query: 163 ETLDF-----------------KKDTEDQESQHESEQDFSQGPCPTVR---------QKL 196
E LD D+ D E + E + + P R ++
Sbjct: 117 EALDSFGGAPLDNSADDADADGPGDSGDGEDELEMTKRLALSDSPDGRPGGFWRRWQPRI 176
Query: 197 WNILEKPGSSTAARIFGVISIIFVVVSIINMALMSAE-----LSWLDLQ----------- 240
W + E P SS AR S+ F++VSI L + E ++ +++
Sbjct: 177 WALFEDPYSSRYARYVAFASLFFILVSITTFCLETHERFNPIVNKTEIENVRNGTQVRYY 236
Query: 241 -------LLEILEYVCISWFTGEFVLRFLCVRDRCRFLRKVPNIIDLLAILPFYITLLVE 293
L +E VC+ WFT EF++R + ++ F++ NIID +AILPFY+ + +
Sbjct: 237 REAETEAFLTYIEGVCVVWFTFEFLMRVIFCPNKVEFIKNSLNIIDFVAILPFYLEVGLS 296
Query: 294 SLSGSQTTQELENVGRIVQVLRLLRALRMLKLGRHSTGLRSLGMTITQCYEEVGLLLLFL 353
LS ++ ++V ++V+R +R LR+ KL RH GLR LG T+ E LL++FL
Sbjct: 297 GLS----SKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFL 352
Query: 354 SVGISIFSTVEYFAEQ---------SIPDTTFTSVPCAWWWATTSMTTVGYGDIRPDTTT 404
++G+ IF+T+ Y+AE+ + T F ++P +WWA +MTT+GYGD+ P T +
Sbjct: 353 ALGVLIFATMIYYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWS 412
Query: 405 GKIVAFMCILSGILVLALPIAIINDRFSACYFTLKLKEAAVRQRE 449
G +V +C L+G+L +A+P+ +I + F Y K+ ++++
Sbjct: 413 GMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKK 457
>gi|163792201 Shaw-related voltage-gated potassium channel protein 1
isoform A [Homo sapiens]
Length = 585
Score = 224 bits (571), Expect = 1e-58
Identities = 141/465 (30%), Positives = 232/465 (49%), Gaps = 77/465 (16%)
Query: 43 VNVGGSRFVLSQQALSCFPHTRLGKLAVVVASYRRPGALAAVPSPLELCDDANPVDNEYF 102
+NVGG+R + L P TRL LA P A + D +P +E+F
Sbjct: 12 INVGGTRHQTYRSTLRTLPGTRLAWLA-------EPDAHSHF--------DYDPRADEFF 56
Query: 103 FDRSSQAFRYVLHYYRTGRLHVMEQLCALSFLQEIQYWGIDELSIDSCCRDRYFRRKELS 162
FDR F ++L+YYRTG+LH +C + +E+ +WGIDE ++ CC Y + ++
Sbjct: 57 FDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAE 116
Query: 163 ETLDF-----------------KKDTEDQESQHESEQDFSQGPCPTVR---------QKL 196
E LD D+ D E + E + + P R ++
Sbjct: 117 EALDSFGGAPLDNSADDADADGPGDSGDGEDELEMTKRLALSDSPDGRPGGFWRRWQPRI 176
Query: 197 WNILEKPGSSTAARIFGVISIIFVVVSIINMALMSAE-----LSWLDLQ----------- 240
W + E P SS AR S+ F++VSI L + E ++ +++
Sbjct: 177 WALFEDPYSSRYARYVAFASLFFILVSITTFCLETHERFNPIVNKTEIENVRNGTQVRYY 236
Query: 241 -------LLEILEYVCISWFTGEFVLRFLCVRDRCRFLRKVPNIIDLLAILPFYITLLVE 293
L +E VC+ WFT EF++R + ++ F++ NIID +AILPFY+ + +
Sbjct: 237 REAETEAFLTYIEGVCVVWFTFEFLMRVIFCPNKVEFIKNSLNIIDFVAILPFYLEVGLS 296
Query: 294 SLSGSQTTQELENVGRIVQVLRLLRALRMLKLGRHSTGLRSLGMTITQCYEEVGLLLLFL 353
LS ++ ++V ++V+R +R LR+ KL RH GLR LG T+ E LL++FL
Sbjct: 297 GLS----SKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFL 352
Query: 354 SVGISIFSTVEYFAEQ---------SIPDTTFTSVPCAWWWATTSMTTVGYGDIRPDTTT 404
++G+ IF+T+ Y+AE+ + T F ++P +WWA +MTT+GYGD+ P T +
Sbjct: 353 ALGVLIFATMIYYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWS 412
Query: 405 GKIVAFMCILSGILVLALPIAIINDRFSACYFTLKLKEAAVRQRE 449
G +V +C L+G+L +A+P+ +I + F Y K+ ++++
Sbjct: 413 GMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKK 457
>gi|4504817 potassium voltage-gated channel, shaker-related
subfamily, member 4 [Homo sapiens]
Length = 653
Score = 219 bits (557), Expect = 6e-57
Identities = 157/524 (29%), Positives = 245/524 (46%), Gaps = 103/524 (19%)
Query: 14 DSGSLTSLDSSVFCSEGEG--EPLALGDC---FTVNVGGSRFVLSQQALSCFPHTRLGKL 68
D G S + EG G + DC +NV G RF + L+ FP T LG
Sbjct: 146 DHGDECSYTDLLPQDEGGGGYSSVRYSDCCERVVINVSGLRFETQMKTLAQFPETLLG-- 203
Query: 69 AVVVASYRRPGALAAVPSPLELCDDANPVDNEYFFDRSSQAFRYVLHYYRTG-RLHVMEQ 127
P + +P+ NEYFFDR+ +F +L+YY++G RL
Sbjct: 204 -----------------DPEKRTQYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLKRPVN 246
Query: 128 LCALSFLQEIQYWGIDELSIDSCCRDRYFRRKELSETLDFKKDTEDQESQHESEQDFSQG 187
+ F +E++++ + E ++ D F R+E L E +F
Sbjct: 247 VPFDIFTEEVKFYQLGEEALLKFREDEGFVREEEDRALP--------------ENEF--- 289
Query: 188 PCPTVRQKLWNILEKPGSSTAARIFGVISIIFVVVSIINMALMSAELSWLDLQLLE---- 243
++++W + E P SS+ AR ++S++ +++SI+ L + D L+
Sbjct: 290 -----KKQIWLLFEYPESSSPARGIAIVSVLVILISIVIFCLETLPEFRDDRDLVMALSA 344
Query: 244 ----------------------------ILEYVCISWFTGEFVLRFLCVRDRCRFLRKVP 275
I+E VCI WF+ EFV+R + F + +
Sbjct: 345 GGHGGLLNDTSAPHLENSGHTIFNDPFFIVETVCIVWFSFEFVVRCFACPSQALFFKNIM 404
Query: 276 NIIDLLAILPFYITL---LVESLSGSQTTQELENVGRIVQVLRLLRALRMLKLGRHSTGL 332
NIID+++ILP++ITL L + G Q+ I++++RL+R R+ KL RHS GL
Sbjct: 405 NIIDIVSILPYFITLGTDLAQQQGGGNGQQQQAMSFAILRIIRLVRVFRIFKLSRHSKGL 464
Query: 333 RSLGMTITQCYEEVGLLLLFLSVGISIFSTVEYFAEQSIPDTTFTSVPCAWWWATTSMTT 392
+ LG T+ E+GLL+ FL +G+ +FS+ YFAE P T F S+P A+WWA +MTT
Sbjct: 465 QILGHTLRASMRELGLLIFFLFIGVILFSSAVYFAEADEPTTHFQSIPDAFWWAVVTMTT 524
Query: 393 VGYGDIRPDTTTGKIVAFMCILSGILVLALPIAIINDRFSACYFTLKLKEAAVRQREALK 452
VGYGD++P T GKIV +C ++G+L +ALP+ +I F+ Y + E
Sbjct: 525 VGYGDMKPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYH-------RETENEEQT 577
Query: 453 KLTKNIATDSYISVNLRDVYARSIMEMLRLKGRERASTRSSGGD 496
+LT+N + Y+ NL + R+ST SS GD
Sbjct: 578 QLTQNAVSCPYLPSNLLKKF--------------RSSTSSSLGD 607
>gi|119395748 potassium voltage-gated channel subfamily A member 1
[Homo sapiens]
Length = 495
Score = 216 bits (550), Expect = 4e-56
Identities = 141/448 (31%), Positives = 235/448 (52%), Gaps = 71/448 (15%)
Query: 43 VNVGGSRFVLSQQALSCFPHTRLGKLAVVVASYRRPGALAAVPSPLELCDDANPVDNEYF 102
+N+ G RF + L+ FP+T LG +P + +P+ NEYF
Sbjct: 41 INISGLRFETQLKTLAQFPNTLLG-------------------NPKKRMRYFDPLRNEYF 81
Query: 103 FDRSSQAFRYVLHYYRTG-RLHVMEQLCALSFLQEIQYWGIDELSIDSCCRDRYFRRKEL 161
FDR+ +F +L+YY++G RL + F +EI+++ + E +++ D F ++E
Sbjct: 82 FDRNRPSFDAILYYYQSGGRLRRPVNVPLDMFSEEIKFYELGEEAMEKFREDEGFIKEE- 140
Query: 162 SETLDFKKDTEDQESQHESEQDFSQGPCPTVRQKLWNILEKPGSSTAARIFGVISIIFVV 221
++ ++E Q + +W + E P SS AR+ ++S++ ++
Sbjct: 141 ------ERPLPEKEYQRQ----------------VWLLFEYPESSGPARVIAIVSVMVIL 178
Query: 222 VSIINMALMSA-EL---------------------SWLDLQLLEILEYVCISWFTGEFVL 259
+SI+ L + EL S + I+E +CI WF+ E V+
Sbjct: 179 ISIVIFCLETLPELKDDKDFTGTVHRIDNTTVIYNSNIFTDPFFIVETLCIIWFSFELVV 238
Query: 260 RFLCVRDRCRFLRKVPNIIDLLAILPFYITLLVE--SLSGSQTTQELENVGRIVQVLRLL 317
RF + F + + N ID++AI+P++ITL E G+Q ++ ++ I++V+RL+
Sbjct: 239 RFFACPSKTDFFKNIMNFIDIVAIIPYFITLGTEIAEQEGNQKGEQATSLA-ILRVIRLV 297
Query: 318 RALRMLKLGRHSTGLRSLGMTITQCYEEVGLLLLFLSVGISIFSTVEYFAEQSIPDTTFT 377
R R+ KL RHS GL+ LG T+ E+GLL+ FL +G+ +FS+ YFAE ++ F+
Sbjct: 298 RVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEAEEAESHFS 357
Query: 378 SVPCAWWWATTSMTTVGYGDIRPDTTTGKIVAFMCILSGILVLALPIAIINDRFSACYFT 437
S+P A+WWA SMTTVGYGD+ P T GKIV +C ++G+L +ALP+ +I F+ YF
Sbjct: 358 SIPDAFWWAVVSMTTVGYGDMYPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFN--YFY 415
Query: 438 LKLKEAAVRQREALKKLTKNIATDSYIS 465
+ E Q + L + N+A+DS +S
Sbjct: 416 HRETEGE-EQAQLLHVSSPNLASDSDLS 442
>gi|5031819 potassium voltage-gated channel, shaker-related
subfamily, member 10 [Homo sapiens]
Length = 511
Score = 214 bits (544), Expect = 2e-55
Identities = 139/460 (30%), Positives = 226/460 (49%), Gaps = 69/460 (15%)
Query: 3 SSGRALLDSPLDSGSLTSLDSSVFCSEGEGEPLALGDC---FTVNVGGSRFVLSQQALSC 59
S+G+ L+ + + S + EP+ L + +N+ G RF + LS
Sbjct: 47 SNGKILISESTNHETAFSKLPGDYADPPGPEPVVLNEGNQRVIINIAGLRFETQLRTLSQ 106
Query: 60 FPHTRLGKLAVVVASYRRPGALAAVPSPLELCDDANPVDNEYFFDRSSQAFRYVLHYYRT 119
FP T LG + + + + NEYFFDR+ +F +L+YY++
Sbjct: 107 FPETLLGDREKRMQFF-------------------DSMRNEYFFDRNRPSFDGILYYYQS 147
Query: 120 G-RLHVMEQLCALSFLQEIQYWGIDELSIDSCCRDRYFRRKELSETLDFKKDTEDQESQH 178
G ++ + F EI ++ + ++D FR E F KD E
Sbjct: 148 GGKIRRPANVPIDIFADEISFYELGSEAMDQ------FREDE-----GFIKDPE------ 190
Query: 179 ESEQDFSQGPCPTVRQKLWNILEKPGSSTAARIFGVISIIFVVVSIINMALMSAELSWLD 238
+ P + ++ W + E P SS+AAR V+S++ VV+SI L + D
Sbjct: 191 ------TLLPTNDIHRQFWLLFEYPESSSAARAVAVVSVLVVVISITIFCLETLPEFRED 244
Query: 239 LQLLEI-----------------------LEYVCISWFTGEFVLRFLCVRDRCRFLRKVP 275
+L + +E CI WFT E VLRF+ + F R +
Sbjct: 245 RELKVVRDPNLNMSKTVLSQTMFTDPFFMVESTCIVWFTFELVLRFVVCPSKTDFFRNIM 304
Query: 276 NIIDLLAILPFYITLLVESLSGSQTTQELENVGRIVQVLRLLRALRMLKLGRHSTGLRSL 335
NIID+++I+P++ TL+ E + ++ + + I++++RL+R R+ KL RHS GL+ L
Sbjct: 305 NIIDIISIIPYFATLITELVQETEPSAQQNMSLAILRIIRLVRVFRIFKLSRHSKGLQIL 364
Query: 336 GMTITQCYEEVGLLLLFLSVGISIFSTVEYFAEQSIPDTTFTSVPCAWWWATTSMTTVGY 395
G T+ E+GLL+ FL +G+ +FS+ YFAE P++ F+S+P +WWA +MTTVGY
Sbjct: 365 GQTLKASMRELGLLIFFLFIGVILFSSAVYFAEVDEPESHFSSIPDGFWWAVVTMTTVGY 424
Query: 396 GDIRPDTTTGKIVAFMCILSGILVLALPIAIINDRFSACY 435
GD+ P T GKIV +C ++G+L +ALP+ +I F+ Y
Sbjct: 425 GDMCPTTPGGKIVGTLCAIAGVLTIALPVPVIVSNFNYFY 464
>gi|4826782 potassium voltage-gated channel, shaker-related
subfamily, member 2 [Homo sapiens]
Length = 499
Score = 211 bits (537), Expect = 1e-54
Identities = 133/424 (31%), Positives = 218/424 (51%), Gaps = 74/424 (17%)
Query: 43 VNVGGSRFVLSQQALSCFPHTRLGKLAVVVASYRRPGALAAVPSPLELCDDANPVDNEYF 102
+N+ G RF + L+ FP T LG P + +P+ NEYF
Sbjct: 37 INISGLRFETQLKTLAQFPETLLG-------------------DPKKRMRYFDPLRNEYF 77
Query: 103 FDRSSQAFRYVLHYYRTG-RLHVMEQLCALSFLQEIQYWGIDELSIDSCCRDRYFRRKEL 161
FDR+ +F +L+YY++G RL + F +EI+++ + E +++ D + ++E
Sbjct: 78 FDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFSEEIRFYELGEEAMEMFREDEGYIKEE- 136
Query: 162 SETLDFKKDTEDQESQHESEQDFSQGPCPTVRQKLWNILEKPGSSTAARIFGVISIIFVV 221
++ + E Q + +W + E P SS ARI ++S++ ++
Sbjct: 137 ------ERPLPENEFQRQ----------------VWLLFEYPESSGPARIIAIVSVMVIL 174
Query: 222 VSIINMALMSAEL--------------------SWLDLQLLE-------ILEYVCISWFT 254
+SI++ L + + S + Q I+E +CI WF+
Sbjct: 175 ISIVSFCLETLPIFRDENEDMHGSGVTFHTYSNSTIGYQQSTSFTDPFFIVETLCIIWFS 234
Query: 255 GEFVLRFLCVRDRCRFLRKVPNIIDLLAILPFYITL---LVESLSGSQTTQELENVGRIV 311
EF++RF + F + NIID++AI+P++ITL L E +Q Q+ ++ I+
Sbjct: 235 FEFLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTELAEKPEDAQQGQQAMSLA-IL 293
Query: 312 QVLRLLRALRMLKLGRHSTGLRSLGMTITQCYEEVGLLLLFLSVGISIFSTVEYFAEQSI 371
+V+RL+R R+ KL RHS GL+ LG T+ E+GLL+ FL +G+ +FS+ YFAE
Sbjct: 294 RVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADE 353
Query: 372 PDTTFTSVPCAWWWATTSMTTVGYGDIRPDTTTGKIVAFMCILSGILVLALPIAIINDRF 431
++ F S+P A+WWA SMTTVGYGD+ P T GKIV +C ++G+L +ALP+ +I F
Sbjct: 354 RESQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNF 413
Query: 432 SACY 435
+ Y
Sbjct: 414 NYFY 417
>gi|88758565 potassium voltage-gated channel, shaker-related
subfamily, member 3 [Homo sapiens]
Length = 575
Score = 209 bits (532), Expect = 5e-54
Identities = 132/434 (30%), Positives = 216/434 (49%), Gaps = 73/434 (16%)
Query: 32 GEPLALGDCFTVNVGGSRFVLSQQALSCFPHTRLGKLAVVVASYRRPGALAAVPSPLELC 91
GE G+ +N+ G RF + L FP T LG P
Sbjct: 97 GEQDCCGERVVINISGLRFETQLKTLCQFPETLLG-------------------DPKRRM 137
Query: 92 DDANPVDNEYFFDRSSQAFRYVLHYYRTG-RLHVMEQLCALSFLQEIQYWGIDELSIDSC 150
+P+ NEYFFDR+ +F +L+YY++G R+ + F +EI+++ + E +++
Sbjct: 138 RYFDPLRNEYFFDRNRPSFDAILYYYQSGGRIRRPVNVPIDIFSEEIRFYQLGEEAMEKF 197
Query: 151 CRDRYFRRKELSETLDFKKDTEDQESQHESEQDFSQGPCPTVRQKLWNILEKPGSSTAAR 210
D F R +E + +DF ++++W + E P SS AR
Sbjct: 198 REDEGFLR---------------EEERPLPRRDF--------QRQVWLLFEYPESSGPAR 234
Query: 211 IFGVISIIFVVVSIINMALMS-----------AELSWLDLQLLE---------------- 243
++S++ +++SI+ L + A S +
Sbjct: 235 GIAIVSVLVILISIVIFCLETLPEFRDEKDYPASTSQDSFEAAGNSTSGSRAGASSFSDP 294
Query: 244 --ILEYVCISWFTGEFVLRFLCVRDRCRFLRKVPNIIDLLAILPFYITLLVESLSGSQTT 301
++E +CI WF+ E ++RF + F R + N+ID++AI+P++ITL E
Sbjct: 295 FFVVETLCIIWFSFELLVRFFACPSKATFSRNIMNLIDIVAIIPYFITLGTELAERQGNG 354
Query: 302 QELENVGRIVQVLRLLRALRMLKLGRHSTGLRSLGMTITQCYEEVGLLLLFLSVGISIFS 361
Q+ ++ I++V+RL+R R+ KL RHS GL+ LG T+ E+GLL+ FL +G+ +FS
Sbjct: 355 QQAMSLA-ILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFS 413
Query: 362 TVEYFAEQSIPDTTFTSVPCAWWWATTSMTTVGYGDIRPDTTTGKIVAFMCILSGILVLA 421
+ YFAE P + F+S+P A+WWA +MTTVGYGD+ P T GKIV +C ++G+L +A
Sbjct: 414 SAVYFAEADDPTSGFSSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIA 473
Query: 422 LPIAIINDRFSACY 435
LP+ +I F+ Y
Sbjct: 474 LPVPVIVSNFNYFY 487
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.138 0.415
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,226,769
Number of Sequences: 37866
Number of extensions: 720490
Number of successful extensions: 3076
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 153
Number of HSP's successfully gapped in prelim test: 48
Number of HSP's that attempted gapping in prelim test: 2521
Number of HSP's gapped (non-prelim): 364
length of query: 500
length of database: 18,247,518
effective HSP length: 106
effective length of query: 394
effective length of database: 14,233,722
effective search space: 5608086468
effective search space used: 5608086468
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.