Search of human proteins with 7657017

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7657017 hypothetical protein LOC25832 [Homo sapiens]
         (921 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7657017 hypothetical protein LOC25832 [Homo sapiens]              1869   0.0  
gi|224589132 hypothetical protein LOC100132406 [Homo sapiens]        1539   0.0  
gi|239741309 PREDICTED: hypothetical protein XP_002344485 [Homo ...  1539   0.0  
gi|169162915 PREDICTED: hypothetical protein LOC728841 [Homo sap...  1539   0.0  
gi|157266285 hypothetical protein LOC728936 [Homo sapiens]           1087   0.0  
gi|29789405 hypothetical protein LOC284565 [Homo sapiens]            1084   0.0  
gi|83415174 hypothetical protein LOC400818 [Homo sapiens]            1081   0.0  
gi|92110019 hypothetical protein LOC55672 [Homo sapiens]             1078   0.0  
gi|156071420 hypothetical protein LOC728912 [Homo sapiens]            880   0.0  
gi|119709825 neuroblastoma breakpoint family, member 11-like [Ho...   880   0.0  
gi|14149997 neuroblastoma breakpoint family, member 3 [Homo sapi...   703   0.0  
gi|239741297 PREDICTED: neuroblastoma breakpoint family, member ...   410   e-114
gi|221136844 neuroblastoma breakpoint family, member 6 isoform 1...   399   e-111
gi|221136848 neuroblastoma breakpoint family, member 6 isoform 2...   395   e-110
gi|221218991 neuroblastoma breakpoint family, member 4 [Homo sap...   395   e-110
gi|114158664 hypothetical protein LOC343505 [Homo sapiens]            335   1e-91
gi|239758011 PREDICTED: hypothetical protein LOC728841, partial ...   231   2e-60
gi|157311604 phosphodiesterase 4D interacting protein isoform 1 ...    78   3e-14
gi|239747446 PREDICTED: similar to Neuroblastoma breakpoint fami...    65   4e-10
gi|239741304 PREDICTED: similar to Neuroblastoma breakpoint fami...    64   8e-10
gi|239741281 PREDICTED: Neuroblastoma breakpoint family member 6...    64   8e-10
gi|239752894 PREDICTED: Neuroblastoma breakpoint family member 6...    61   5e-09
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho...    59   2e-08
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho...    59   2e-08
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho...    59   2e-08
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho...    59   2e-08
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li...    55   4e-07
gi|21735548 centrosomal protein 2 [Homo sapiens]                       54   5e-07
gi|148746195 trichohyalin [Homo sapiens]                               48   5e-05
gi|48255889 protein kinase C substrate 80K-H isoform 1 [Homo sap...    47   6e-05

>gi|7657017 hypothetical protein LOC25832 [Homo sapiens]
          Length = 921

 Score = 1869 bits (4842), Expect = 0.0
 Identities = 921/921 (100%), Positives = 921/921 (100%)

Query: 1   MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQA 60
           MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQA
Sbjct: 1   MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQA 60

Query: 61  LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR 120
           LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR
Sbjct: 61  LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR 120

Query: 121 EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEW 180
           EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEW
Sbjct: 121 EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEW 180

Query: 181 EDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYKS 240
           EDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYKS
Sbjct: 181 EDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYKS 240

Query: 241 YSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDHEATGPRLSRELLDEKGPEVLQDSLDRCY 300
           YSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDHEATGPRLSRELLDEKGPEVLQDSLDRCY
Sbjct: 241 YSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDHEATGPRLSRELLDEKGPEVLQDSLDRCY 300

Query: 301 STPSGCLELTDSCQPYRSAFYVLEQQRVGLAVNMDEIEKYQEVEEDQDPSCPRLSRELLD 360
           STPSGCLELTDSCQPYRSAFYVLEQQRVGLAVNMDEIEKYQEVEEDQDPSCPRLSRELLD
Sbjct: 301 STPSGCLELTDSCQPYRSAFYVLEQQRVGLAVNMDEIEKYQEVEEDQDPSCPRLSRELLD 360

Query: 361 EKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEE 420
           EKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEE
Sbjct: 361 EKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEE 420

Query: 421 DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGF 480
           DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGF
Sbjct: 421 DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGF 480

Query: 481 SLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSL 540
           SLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSL
Sbjct: 481 SLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSL 540

Query: 541 DRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSG 600
           DRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSG
Sbjct: 541 DRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSG 600

Query: 601 ELLDEKEPEVLQESLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQ 660
           ELLDEKEPEVLQESLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQ
Sbjct: 601 ELLDEKEPEVLQESLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQ 660

Query: 661 EVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQ 720
           EVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQ
Sbjct: 661 EVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQ 720

Query: 721 YLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPD 780
           YLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPD
Sbjct: 721 YLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPD 780

Query: 781 SCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCP 840
           SCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCP
Sbjct: 781 SCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCP 840

Query: 841 RLNSMLMEVEEPEVLQDSLDICYSTPSMYFELPDSFQHYRSVFYSFEEEHISFALYVDNR 900
           RLNSMLMEVEEPEVLQDSLDICYSTPSMYFELPDSFQHYRSVFYSFEEEHISFALYVDNR
Sbjct: 841 RLNSMLMEVEEPEVLQDSLDICYSTPSMYFELPDSFQHYRSVFYSFEEEHISFALYVDNR 900

Query: 901 FFTLTVTSLHLVFQMGVIFPQ 921
           FFTLTVTSLHLVFQMGVIFPQ
Sbjct: 901 FFTLTVTSLHLVFQMGVIFPQ 921


>gi|224589132 hypothetical protein LOC100132406 [Homo sapiens]
          Length = 3628

 Score = 1539 bits (3984), Expect = 0.0
 Identities = 775/917 (84%), Positives = 812/917 (88%), Gaps = 38/917 (4%)

Query: 1    MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQA 60
            MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQL+EKLREGRDASRSLNEHLQA
Sbjct: 341  MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLKEKLREGRDASRSLNEHLQA 400

Query: 61   LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR 120
            LLTP EPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR
Sbjct: 401  LLTPYEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR 460

Query: 121  EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEW 180
            EMQKAEEKEVPEDSLEECAIT SNSHG YDSNQPHRKTKITFEEDKVDSTLIGSSSHVEW
Sbjct: 461  EMQKAEEKEVPEDSLEECAITYSNSHGSYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEW 520

Query: 181  EDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYKS 240
            EDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASY+S
Sbjct: 521  EDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQS 580

Query: 241  YSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDHEATGPRLSRELLDEKGPEVLQDSLDRCY 300
            YSSTFHSLEEQQVCMAVDIGRHRWDQVKKED EATGPRLSRELLDEKGPEV QDS DRCY
Sbjct: 581  YSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVFQDSQDRCY 640

Query: 301  STPSGCLELTDSCQPYRSAFYVLEQQRVGLAVNMDEIEKYQEVEEDQDPSCPRLSRELLD 360
            STPSGCLELTDSCQPYRSAFY+LEQQRVGLA++MDEIEKYQEVEEDQDPSCPRLSRELLD
Sbjct: 641  STPSGCLELTDSCQPYRSAFYILEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLD 700

Query: 361  EKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEE 420
            EKEPEVLQDSL RCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEE
Sbjct: 701  EKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEE 760

Query: 421  DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGF 480
            DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGF
Sbjct: 761  DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGF 820

Query: 481  SLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSL 540
            SLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSL
Sbjct: 821  SLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSL 880

Query: 541  DRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSG 600
            DRCYSTPSGCLELTDSCQPYRSAFY+LEQQRVG AVDMDEIEKYQEVEEDQDPSCPRLS 
Sbjct: 881  DRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSR 940

Query: 601  ELLDEKEPEVLQESLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQ 660
            ELLDEKEPEVLQ+SLDRCYSTPSG LEL D  QPY SA Y LE+Q +GLA+D+D I+K Q
Sbjct: 941  ELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQ 1000

Query: 661  EVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQ 720
            E EEDQ P CPRLSRELL+  EPEVLQDSL RCYSTPS  LE PD  QPY S+ Y+LEE+
Sbjct: 1001 EEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEK 1060

Query: 721  YLGLALDVDRIKKD-------------------QEEEEDQGPPCPRLSRELLEVVEPEVL 761
            ++G +LDV  I+K                    +E EEDQ PPCPRLSRELL+   PEVL
Sbjct: 1061 HVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVL 1120

Query: 762  QDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSK 821
            QDSLDRCYSTPS CLE  DSCQPY S+FY LE++ VGF++D+ EIEK             
Sbjct: 1121 QDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEK------------- 1167

Query: 822  KERRRGRKEGEEDQNPPCPRLNSMLMEVEEPEVLQDSLDICYSTPSMYFELPDSFQHYRS 881
                   +E EEDQ+P CPRL+  L++ +EPEVLQDSLD CYSTPS Y ELPD  Q Y S
Sbjct: 1168 ------YQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSS 1221

Query: 882  VFYSFEEEHISFALYVD 898
              YS EE+++  AL VD
Sbjct: 1222 AVYSLEEQYLGLALDVD 1238



 Score = 1250 bits (3235), Expect = 0.0
 Identities = 645/824 (78%), Positives = 683/824 (82%), Gaps = 39/824 (4%)

Query: 100  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHR 156
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 2627 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 2686

Query: 157  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 213
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 2687 SAVYSLEEQYLGLALD--------------VDRIKKDQEEEEDQGPPCPRLSRELLEVVE 2732

Query: 214  EEVPQESWDEGYSTLSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIG------------- 260
             EV Q+S D  YST S   E   S + Y S+F++LEE+ V  ++D+G             
Sbjct: 2733 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 2792

Query: 261  ------RHRWDQVKKEDHEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 314
                  R R  +  +ED     PRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 2793 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 2852

Query: 315  PYRSAFYVLEQQRVGLAVNMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRC 374
            PYRSAFYVLEQQ VGLAV+MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL RC
Sbjct: 2853 PYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 2912

Query: 375  YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 434
            YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL
Sbjct: 2913 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 2972

Query: 435  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 494
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 2973 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 3032

Query: 495  KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 554
            KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGP+VLQDSLDRCYSTPSGCLEL 
Sbjct: 3033 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPKVLQDSLDRCYSTPSGCLELC 3092

Query: 555  DSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQES 614
            DSCQPYRSAFY+LEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLS ELLDEK PEVLQ+S
Sbjct: 3093 DSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKGPEVLQDS 3152

Query: 615  LDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLS 674
            LDRCYSTPSGCLEL DSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLS
Sbjct: 3153 LDRCYSTPSGCLELCDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLS 3212

Query: 675  RELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKD 734
            RELLDEKEPEVLQDSL RCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKD
Sbjct: 3213 RELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKD 3272

Query: 735  QEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEE 794
            QEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEE
Sbjct: 3273 QEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEE 3332

Query: 795  KHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNSMLMEVEEPEV 854
            KHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRL+  L++ + PEV
Sbjct: 3333 KHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEV 3392

Query: 855  LQDSLDICYSTPSMYFELPDSFQHYRSVFYSFEEEHISFALYVD 898
            LQDSLD CYSTPS   EL DS Q YRS FY  E++H+  A+ +D
Sbjct: 3393 LQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQQHVGLAVDMD 3436



 Score = 1062 bits (2746), Expect = 0.0
 Identities = 567/843 (67%), Positives = 624/843 (74%), Gaps = 77/843 (9%)

Query: 100  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHR 156
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 2139 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 2198

Query: 157  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 213
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 2199 SAVYSLEEQYLGLALD--------------VDRIKKDQEEEEDQGPPCPRLSRELLEVVE 2244

Query: 214  EEVPQESWDEGYSTLSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIG------------- 260
             EV Q+S D  YST S   E   S + Y S+F++LEE  V  ++D+G             
Sbjct: 2245 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRG 2304

Query: 261  ------RHRWDQVKKEDHEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 314
                  R R  +  +ED     PRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 2305 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 2364

Query: 315  PYRSAFYVLEQQRVGLAVNMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRC 374
            PYRSAFYVLEQQ VGLAV+MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL RC
Sbjct: 2365 PYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 2424

Query: 375  YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 434
            YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL
Sbjct: 2425 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 2484

Query: 435  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 494
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEE HVGFSLDVGEIEKKGKGK
Sbjct: 2485 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGK 2544

Query: 495  KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 554
            KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT
Sbjct: 2545 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 2604

Query: 555  DSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQES 614
            DSCQPYRSAFY+LEQQ VGLAVDMDEIEKYQEVEEDQDPSCPRLS ELLDEKEPEVLQ+S
Sbjct: 2605 DSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDS 2664

Query: 615  LDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLS 674
            LDRCYSTPSG LEL D  QPY SA Y LE+Q +GLA+D+D I+K QE EEDQ P CPRLS
Sbjct: 2665 LDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLS 2724

Query: 675  RELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKD 734
            RELL+  EPEVLQDSL RCYSTPS  LE PD  QPY S+ Y+LEE+++G +LDV  I+K 
Sbjct: 2725 RELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKK 2784

Query: 735  -------------------QEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSC 775
                               +E EEDQ PPCPRLSRELL+   PEVLQDSLDRCYSTPS C
Sbjct: 2785 GKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGC 2844

Query: 776  LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQ 835
            LE  DSCQPY S+FY LE++HVG ++D+ EIEK                    +E EEDQ
Sbjct: 2845 LELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEK-------------------YQEVEEDQ 2885

Query: 836  NPPCPRLNSMLMEVEEPEVLQDSLDICYSTPSMYFELPDSFQHYRSVFYSFEEEHISFAL 895
            +P CPRL+  L++ +EPEVLQDSLD CYSTPS Y ELPD  Q Y S  YS EE+++  AL
Sbjct: 2886 DPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 2945

Query: 896  YVD 898
             VD
Sbjct: 2946 DVD 2948



 Score = 1061 bits (2745), Expect = 0.0
 Identities = 567/843 (67%), Positives = 623/843 (73%), Gaps = 77/843 (9%)

Query: 100  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHR 156
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 1651 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 1710

Query: 157  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 213
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 1711 SAVYSLEEQYLGLALD--------------VDRIKKDQEEEEDQGPPCPRLSRELLEVVE 1756

Query: 214  EEVPQESWDEGYSTLSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIG------------- 260
             EV Q+S D  YST S   E   S + Y S+F++LEE  V  ++D+G             
Sbjct: 1757 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRG 1816

Query: 261  ------RHRWDQVKKEDHEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 314
                  R R  +  +ED     PRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 1817 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 1876

Query: 315  PYRSAFYVLEQQRVGLAVNMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRC 374
            PYRSAFYVLEQQ VGLAV+MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL RC
Sbjct: 1877 PYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 1936

Query: 375  YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 434
            YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL
Sbjct: 1937 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 1996

Query: 435  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 494
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEE HVGFSLDVGEIEKKGKGK
Sbjct: 1997 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGK 2056

Query: 495  KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 554
            KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT
Sbjct: 2057 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 2116

Query: 555  DSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQES 614
            DSCQPYRSAFY+LEQQ VGLAVDMDEIEKYQEVEEDQDPSCPRLS ELLDEKEPEVLQ+S
Sbjct: 2117 DSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDS 2176

Query: 615  LDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLS 674
            LDRCYSTPSG LEL D  QPY SA Y LE+Q +GLA+D+D I+K QE EEDQ P CPRLS
Sbjct: 2177 LDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLS 2236

Query: 675  RELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKD 734
            RELL+  EPEVLQDSL RCYSTPS  LE PD  QPY S+ Y+LEE ++G +LDV  I+K 
Sbjct: 2237 RELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKK 2296

Query: 735  -------------------QEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSC 775
                               +E EEDQ PPCPRLSRELL+   PEVLQDSLDRCYSTPS C
Sbjct: 2297 GKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGC 2356

Query: 776  LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQ 835
            LE  DSCQPY S+FY LE++HVG ++D+ EIEK                    +E EEDQ
Sbjct: 2357 LELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEK-------------------YQEVEEDQ 2397

Query: 836  NPPCPRLNSMLMEVEEPEVLQDSLDICYSTPSMYFELPDSFQHYRSVFYSFEEEHISFAL 895
            +P CPRL+  L++ +EPEVLQDSLD CYSTPS Y ELPD  Q Y S  YS EE+++  AL
Sbjct: 2398 DPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 2457

Query: 896  YVD 898
             VD
Sbjct: 2458 DVD 2460



 Score = 1061 bits (2745), Expect = 0.0
 Identities = 567/843 (67%), Positives = 623/843 (73%), Gaps = 77/843 (9%)

Query: 100  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHR 156
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 1895 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 1954

Query: 157  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 213
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 1955 SAVYSLEEQYLGLALD--------------VDRIKKDQEEEEDQGPPCPRLSRELLEVVE 2000

Query: 214  EEVPQESWDEGYSTLSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIG------------- 260
             EV Q+S D  YST S   E   S + Y S+F++LEE  V  ++D+G             
Sbjct: 2001 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRG 2060

Query: 261  ------RHRWDQVKKEDHEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 314
                  R R  +  +ED     PRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 2061 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 2120

Query: 315  PYRSAFYVLEQQRVGLAVNMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRC 374
            PYRSAFYVLEQQ VGLAV+MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL RC
Sbjct: 2121 PYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 2180

Query: 375  YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 434
            YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL
Sbjct: 2181 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 2240

Query: 435  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 494
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEE HVGFSLDVGEIEKKGKGK
Sbjct: 2241 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGK 2300

Query: 495  KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 554
            KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT
Sbjct: 2301 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 2360

Query: 555  DSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQES 614
            DSCQPYRSAFY+LEQQ VGLAVDMDEIEKYQEVEEDQDPSCPRLS ELLDEKEPEVLQ+S
Sbjct: 2361 DSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDS 2420

Query: 615  LDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLS 674
            LDRCYSTPSG LEL D  QPY SA Y LE+Q +GLA+D+D I+K QE EEDQ P CPRLS
Sbjct: 2421 LDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLS 2480

Query: 675  RELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKD 734
            RELL+  EPEVLQDSL RCYSTPS  LE PD  QPY S+ Y+LEE ++G +LDV  I+K 
Sbjct: 2481 RELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKK 2540

Query: 735  -------------------QEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSC 775
                               +E EEDQ PPCPRLSRELL+   PEVLQDSLDRCYSTPS C
Sbjct: 2541 GKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGC 2600

Query: 776  LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQ 835
            LE  DSCQPY S+FY LE++HVG ++D+ EIEK                    +E EEDQ
Sbjct: 2601 LELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEK-------------------YQEVEEDQ 2641

Query: 836  NPPCPRLNSMLMEVEEPEVLQDSLDICYSTPSMYFELPDSFQHYRSVFYSFEEEHISFAL 895
            +P CPRL+  L++ +EPEVLQDSLD CYSTPS Y ELPD  Q Y S  YS EE+++  AL
Sbjct: 2642 DPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 2701

Query: 896  YVD 898
             VD
Sbjct: 2702 DVD 2704



 Score = 1059 bits (2739), Expect = 0.0
 Identities = 565/843 (67%), Positives = 625/843 (74%), Gaps = 77/843 (9%)

Query: 100  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHR 156
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 673  DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 732

Query: 157  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 213
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 733  SAVYSLEEQYLGLALD--------------VDRIKKDQEEEEDQGPPCPRLSRELLEVVE 778

Query: 214  EEVPQESWDEGYSTLSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIG------------- 260
             EV Q+S D  YST S   E   S + Y S+F++LEE+ V  ++D+G             
Sbjct: 779  PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 838

Query: 261  ------RHRWDQVKKEDHEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 314
                  R R  +  +ED     PRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 839  RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 898

Query: 315  PYRSAFYVLEQQRVGLAVNMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRC 374
            PYRSAFYVLEQQRVG AV+MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL RC
Sbjct: 899  PYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 958

Query: 375  YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 434
            YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL
Sbjct: 959  YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 1018

Query: 435  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 494
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 1019 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 1078

Query: 495  KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 554
            KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT
Sbjct: 1079 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 1138

Query: 555  DSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQES 614
            DSCQPYRSAFY+LEQQRVG AVDMDEIEKYQEVEEDQDPSCPRLS ELLDEKEPEVLQ+S
Sbjct: 1139 DSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDS 1198

Query: 615  LDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLS 674
            LDRCYSTPSG LEL D  QPY SA Y LE+Q +GLA+D+D I+K +E EEDQDP CPRLS
Sbjct: 1199 LDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLS 1258

Query: 675  RELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKD 734
            RELL+   PEVLQDSL RCYSTPS  LE PD  QPY S+ Y+LEE+++G +LDV  I+K 
Sbjct: 1259 RELLEVVAPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKK 1318

Query: 735  -------------------QEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSC 775
                               +E EEDQ PPCPRLSRELL+   PEVLQDSLDRCYSTPS C
Sbjct: 1319 GKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGC 1378

Query: 776  LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQ 835
            LE  DSCQPY S+FY LE++ VG ++D+ EIEK                    +E EEDQ
Sbjct: 1379 LELTDSCQPYRSAFYVLEQQRVGMAVDMDEIEK-------------------YQEVEEDQ 1419

Query: 836  NPPCPRLNSMLMEVEEPEVLQDSLDICYSTPSMYFELPDSFQHYRSVFYSFEEEHISFAL 895
            +P CPRL+  L++ +EPEVLQDSL+ CYSTPS Y ELPD  Q Y S  YS EE+++  AL
Sbjct: 1420 DPSCPRLSRELLDEKEPEVLQDSLNRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 1479

Query: 896  YVD 898
             VD
Sbjct: 1480 DVD 1482



 Score = 1058 bits (2735), Expect = 0.0
 Identities = 566/843 (67%), Positives = 624/843 (74%), Gaps = 75/843 (8%)

Query: 100  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHR 156
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL  C  T S      D  QP+ 
Sbjct: 1405 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLNRCYSTPSGYLELPDLGQPYS 1464

Query: 157  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 213
                + EE  +   L          D   I  + + ++EE+E++ P  PR    L E  E
Sbjct: 1465 SAVYSLEEQYLGLAL----------DVDRI--KKDQEEEEDEDQDPPCPRLSRELLEVVE 1512

Query: 214  EEVPQESWDEGYSTLSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIG------------- 260
             EV Q+S D  YST S   E   S + Y S+F++LEE  V  ++D+G             
Sbjct: 1513 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRG 1572

Query: 261  ------RHRWDQVKKEDHEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 314
                  R R  +  +ED     PRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 1573 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 1632

Query: 315  PYRSAFYVLEQQRVGLAVNMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRC 374
            PYRSAFYVLEQQ VGLAV+MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL RC
Sbjct: 1633 PYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 1692

Query: 375  YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 434
            YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL
Sbjct: 1693 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 1752

Query: 435  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 494
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEE HVGFSLDVGEIEKKGKGK
Sbjct: 1753 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGK 1812

Query: 495  KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 554
            KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT
Sbjct: 1813 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 1872

Query: 555  DSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQES 614
            DSCQPYRSAFY+LEQQ VGLAVDMDEIEKYQEVEEDQDPSCPRLS ELLDEKEPEVLQ+S
Sbjct: 1873 DSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDS 1932

Query: 615  LDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLS 674
            LDRCYSTPSG LEL D  QPY SA Y LE+Q +GLA+D+D I+K QE EEDQ P CPRLS
Sbjct: 1933 LDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLS 1992

Query: 675  RELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKD 734
            RELL+  EPEVLQDSL RCYSTPS  LE PD  QPY S+ Y+LEE ++G +LDV  I+K 
Sbjct: 1993 RELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKK 2052

Query: 735  -------------------QEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSC 775
                               +E EEDQ PPCPRLSRELL+   PEVLQDSLDRCYSTPS C
Sbjct: 2053 GKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGC 2112

Query: 776  LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQ 835
            LE  DSCQPY S+FY LE++HVG ++D+ EIEK                    +E EEDQ
Sbjct: 2113 LELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEK-------------------YQEVEEDQ 2153

Query: 836  NPPCPRLNSMLMEVEEPEVLQDSLDICYSTPSMYFELPDSFQHYRSVFYSFEEEHISFAL 895
            +P CPRL+  L++ +EPEVLQDSLD CYSTPS Y ELPD  Q Y S  YS EE+++  AL
Sbjct: 2154 DPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 2213

Query: 896  YVD 898
             VD
Sbjct: 2214 DVD 2216



 Score = 1055 bits (2728), Expect = 0.0
 Identities = 565/845 (66%), Positives = 625/845 (73%), Gaps = 79/845 (9%)

Query: 100  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHR 156
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 917  DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 976

Query: 157  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 213
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 977  SAVYSLEEQYLGLALD--------------VDRIKKDQEEEEDQGPPCPRLSRELLEVVE 1022

Query: 214  EEVPQESWDEGYSTLSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIG------------- 260
             EV Q+S D  YST S   E   S + Y S+F++LEE+ V  ++D+G             
Sbjct: 1023 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 1082

Query: 261  ------RHRWDQVKKEDHEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 314
                  R R  +  +ED     PRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 1083 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 1142

Query: 315  PYRSAFYVLEQQRVGLAVNMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRC 374
            PYRSAFYVLEQQRVG AV+MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL RC
Sbjct: 1143 PYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 1202

Query: 375  YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 434
            YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKD+EEEEDQ PPCPRLSRELL
Sbjct: 1203 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELL 1262

Query: 435  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 494
            EVV PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 1263 EVVAPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 1322

Query: 495  KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 554
            KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT
Sbjct: 1323 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 1382

Query: 555  DSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQES 614
            DSCQPYRSAFY+LEQQRVG+AVDMDEIEKYQEVEEDQDPSCPRLS ELLDEKEPEVLQ+S
Sbjct: 1383 DSCQPYRSAFYVLEQQRVGMAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDS 1442

Query: 615  LDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVE--EDQDPSCPR 672
            L+RCYSTPSG LEL D  QPY SA Y LE+Q +GLA+D+D I+K QE E  EDQDP CPR
Sbjct: 1443 LNRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDEDQDPPCPR 1502

Query: 673  LSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIK 732
            LSRELL+  EPEVLQDSL RCYSTPS  LE PD  QPY S+ Y+LEE ++G +LDV  I+
Sbjct: 1503 LSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIE 1562

Query: 733  KD-------------------QEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPS 773
            K                    +E EEDQ PPCPRLSRELL+   PEVLQDSLDRCYSTPS
Sbjct: 1563 KKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPS 1622

Query: 774  SCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEE 833
             CLE  DSCQPY S+FY LE++HVG ++D+ EIEK                    +E EE
Sbjct: 1623 GCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEK-------------------YQEVEE 1663

Query: 834  DQNPPCPRLNSMLMEVEEPEVLQDSLDICYSTPSMYFELPDSFQHYRSVFYSFEEEHISF 893
            DQ+P CPRL+  L++ +EPEVLQDSLD CYSTPS Y ELPD  Q Y S  YS EE+++  
Sbjct: 1664 DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGL 1723

Query: 894  ALYVD 898
            AL VD
Sbjct: 1724 ALDVD 1728



 Score = 1050 bits (2715), Expect = 0.0
 Identities = 562/843 (66%), Positives = 622/843 (73%), Gaps = 77/843 (9%)

Query: 100  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHR 156
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 2383 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 2442

Query: 157  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 213
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 2443 SAVYSLEEQYLGLALD--------------VDRIKKDQEEEEDQGPPCPRLSRELLEVVE 2488

Query: 214  EEVPQESWDEGYSTLSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIG------------- 260
             EV Q+S D  YST S   E   S + Y S+F++LEE  V  ++D+G             
Sbjct: 2489 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRG 2548

Query: 261  ------RHRWDQVKKEDHEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 314
                  R R  +  +ED     PRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 2549 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 2608

Query: 315  PYRSAFYVLEQQRVGLAVNMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRC 374
            PYRSAFYVLEQQ VGLAV+MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL RC
Sbjct: 2609 PYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 2668

Query: 375  YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 434
            YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL
Sbjct: 2669 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 2728

Query: 435  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 494
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 2729 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 2788

Query: 495  KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 554
            KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT
Sbjct: 2789 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 2848

Query: 555  DSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQES 614
            DSCQPYRSAFY+LEQQ VGLAVDMDEIEKYQEVEEDQDPSCPRLS ELLDEKEPEVLQ+S
Sbjct: 2849 DSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDS 2908

Query: 615  LDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLS 674
            LDRCYSTPSG LEL D  QPY SA Y LE+Q +GLA+D+D I+K QE EEDQ P CPRLS
Sbjct: 2909 LDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLS 2968

Query: 675  RELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKD 734
            RELL+  EPEVLQDSL RCYSTPS  LE PD  QPY S+ Y+LEE+++G +LDV  I+K 
Sbjct: 2969 RELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKK 3028

Query: 735  -------------------QEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSC 775
                               +E EEDQ PPCPRLSRELL+   P+VLQDSLDRCYSTPS C
Sbjct: 3029 GKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPKVLQDSLDRCYSTPSGC 3088

Query: 776  LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQ 835
            LE  DSCQPY S+FY LE++ VG ++D+ EIEK                    +E EEDQ
Sbjct: 3089 LELCDSCQPYRSAFYVLEQQRVGLAVDMDEIEK-------------------YQEVEEDQ 3129

Query: 836  NPPCPRLNSMLMEVEEPEVLQDSLDICYSTPSMYFELPDSFQHYRSVFYSFEEEHISFAL 895
            +P CPRL+  L++ + PEVLQDSLD CYSTPS   EL DS Q YRS FY  E++ +  A+
Sbjct: 3130 DPSCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYILEQQRVGLAV 3189

Query: 896  YVD 898
             +D
Sbjct: 3190 DMD 3192



 Score =  962 bits (2488), Expect = 0.0
 Identities = 523/843 (62%), Positives = 602/843 (71%), Gaps = 74/843 (8%)

Query: 120  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 179
            RE+   +  EV +DSL+ C  T S      DS QP+R      E+  V   +        
Sbjct: 2819 RELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVD------- 2871

Query: 180  WEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTLSIPPEMLA 236
                   + E E   E EE++ P  PR    L + +E EV Q+S D  YST S   E+  
Sbjct: 2872 -------MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPD 2924

Query: 237  SYKSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDHEATGPRLSRELLDEKGPEVLQDSL 296
              + YSS  +SLEEQ + +A+D+ R + DQ ++ED     PRLSRELL+   PEVLQDSL
Sbjct: 2925 LGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSL 2984

Query: 297  DRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVNMDEIEKY---------------- 340
            DRCYSTPS CLE  DSCQPY S+FY LE++ VG ++++ EIEK                 
Sbjct: 2985 DRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERR 3044

Query: 341  ---QEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYS 397
               +E EEDQ+P CPRLSRELLDEK P+VLQDSL RCYSTPSG LEL D  QPY SA Y 
Sbjct: 3045 RGRKEGEEDQNPPCPRLSRELLDEKGPKVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYV 3104

Query: 398  LEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL 457
            LE+Q +GLA+D+D I+K QE EEDQ P CPRLSRELL+   PEVLQDSLDRCYSTPS CL
Sbjct: 3105 LEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCL 3164

Query: 458  EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQN 517
            E  DSCQPY S+FY LE++ VG ++D+ EIEK                    +E EEDQ+
Sbjct: 3165 ELCDSCQPYRSAFYILEQQRVGLAVDMDEIEKY-------------------QEVEEDQD 3205

Query: 518  PPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVD 577
            P CPRLSRELLDEK PEVLQDSLDRCYSTPSG LEL D  QPY SA Y LE+Q +GLA+D
Sbjct: 3206 PSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALD 3265

Query: 578  MDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQESLDRCYSTPSGCLELTDSCQPYRS 637
            +D I+K QE EEDQ P CPRLS ELL+  EPEVLQ+SLDRCYSTPS CLE  DSCQPY S
Sbjct: 3266 VDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGS 3325

Query: 638  AFYILEQQRVGLAVDMDEIEKY-------------------QEVEEDQDPSCPRLSRELL 678
            +FY LE++ VG ++D+ EIEK                    +E EEDQ+P CPRLSRELL
Sbjct: 3326 SFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELL 3385

Query: 679  DEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEE 738
            DEK PEVLQDSL RCYSTPSG LEL D  QPY SA Y LE+Q++GLA+D+D I+K QE E
Sbjct: 3386 DEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVE 3445

Query: 739  EDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVG 798
            EDQ P CPRLSRELL+  EPEVLQDSLDRCYSTPS  LE PD  QPY S+ Y+LEE+++G
Sbjct: 3446 EDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLG 3505

Query: 799  FSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNSMLMEVEEPEVLQDS 858
             +LDV +IEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLN +LMEVEE EVLQDS
Sbjct: 3506 LALDVDKIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEREVLQDS 3565

Query: 859  LDICYSTPSMYFELPDSFQHYRSVFYSFEEEHISFALYVDNRFFTLTVTSLHLVFQMGVI 918
            LD CYSTPSMYFELPDSFQHYRSVFYSFEE+HISFALYVDNRFFTLTVTSLHLVFQMGVI
Sbjct: 3566 LDRCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYVDNRFFTLTVTSLHLVFQMGVI 3625

Query: 919  FPQ 921
            FPQ
Sbjct: 3626 FPQ 3628



 Score =  867 bits (2241), Expect = 0.0
 Identities = 520/981 (53%), Positives = 607/981 (61%), Gaps = 139/981 (14%)

Query: 1   MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQA 60
           MLRNERQFKEEKLAEQLKQAEELRQYKVLVH+QERELTQLREKLREGRDASRSL EHLQA
Sbjct: 70  MLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLYEHLQA 129

Query: 61  LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR 120
           LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPEND D+DEDVQVE AEKV +SSAPR
Sbjct: 130 LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAEKVLESSAPR 189

Query: 121 EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLI--GSSSHV 178
           E+QKAEE +VPEDSLEECAITCSNSHGP DSNQPH+  KITFEED+V+STL+    SSH 
Sbjct: 190 EVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTLVVDRESSHD 249

Query: 179 EWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASY 238
           E +DA++I+P            GP S            P  S     + L I  ++    
Sbjct: 250 ECQDALNILP----------VPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQL 299

Query: 239 KSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDHEATGP------RLSRELLDEK----- 287
                 F +L+E+  C    +     +Q KK  +E          R  R+  +EK     
Sbjct: 300 AEKKQQFRNLKEK--CFLTQLSGFLANQQKKYKYEECKDLIKFMLRNERQFKEEKLAEQL 357

Query: 288 ----------------------GPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQ 325
                                   E L++  D   S       L    +P +S    L++
Sbjct: 358 KQAEELRQYKVLVHAQERELTQLKEKLREGRDASRSLNEHLQALLTPYEPDKSQGQDLQE 417

Query: 326 QRV---GLAVNM------------DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDS 370
           Q      LA ++            DE  + +  E+ Q  S P   RE+   +E EV +DS
Sbjct: 418 QLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAP---REMQKAEEKEVPEDS 474

Query: 371 LGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL--------------DVDRIKKDQ 416
           L  C  T S      D  QP+     + EE  +   L               +   + D 
Sbjct: 475 LEECAITYSNSHGSYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDD 534

Query: 417 EEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEK 476
           EEEE++GP  P   R L E  E EV Q+S D  YST S   E   S Q Y S+F++LEE+
Sbjct: 535 EEEEEKGPVSP---RNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQ 591

Query: 477 HVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVL 536
            V  ++D+G                   R R  +  +EDQ    PRLSRELLDEKGPEV 
Sbjct: 592 QVCMAVDIG-------------------RHRWDQVKKEDQEATGPRLSRELLDEKGPEVF 632

Query: 537 QDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCP 596
           QDS DRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLA+DMDEIEKYQEVEEDQDPSCP
Sbjct: 633 QDSQDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAIDMDEIEKYQEVEEDQDPSCP 692

Query: 597 RLSGELLDEKEPEVLQESLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEI 656
           RLS ELLDEKEPEVLQ+SLDRCYSTPSG LEL D  QPY SA Y LE+Q +GLA+D+D I
Sbjct: 693 RLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRI 752

Query: 657 EKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYS 716
           +K QE EEDQ P CPRLSRELL+  EPEVLQDSL RCYSTPS  LE PD  QPY S+ Y+
Sbjct: 753 KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYA 812

Query: 717 LEEQYLGLALDVDRIKKD-------------------QEEEEDQGPPCPRLSRELLEVVE 757
           LEE+++G +LDV  I+K                    +E EEDQ PPCPRLSRELL+   
Sbjct: 813 LEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKG 872

Query: 758 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 817
           PEVLQDSLDRCYSTPS CLE  DSCQPY S+FY LE++ VGF++D+ EIEK         
Sbjct: 873 PEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEK--------- 923

Query: 818 RRSKKERRRGRKEGEEDQNPPCPRLNSMLMEVEEPEVLQDSLDICYSTPSMYFELPDSFQ 877
                      +E EEDQ+P CPRL+  L++ +EPEVLQDSLD CYSTPS Y ELPD  Q
Sbjct: 924 ----------YQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQ 973

Query: 878 HYRSVFYSFEEEHISFALYVD 898
            Y S  YS EE+++  AL VD
Sbjct: 974 PYSSAVYSLEEQYLGLALDVD 994



 Score =  857 bits (2215), Expect = 0.0
 Identities = 473/748 (63%), Positives = 539/748 (72%), Gaps = 54/748 (7%)

Query: 21   EELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPD---------EPDKSQ 71
            +E+ +Y+ +   Q+    +L  +L + ++     +   +   TP          +P  S 
Sbjct: 2873 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 2932

Query: 72   GQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR---EMQKAEEK 128
               L+EQ   G  L    ++K     D +++ED         Q    PR   E+ +  E 
Sbjct: 2933 VYSLEEQYL-GLALDVDRIKK-----DQEEEED---------QGPPCPRLSRELLEVVEP 2977

Query: 129  EVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIP 188
            EV +DSL+ C  T S+     DS QP+  +    EE  V  +L       + +       
Sbjct: 2978 EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGR 3037

Query: 189  ENESD-----DEEEEEKGPVSPRNLQESEEEEVP---QESWDEGYSTLSIPPEMLASYKS 240
             ++ +      E EE++ P  PR  +E  +E+ P   Q+S D  YST S   E+  S + 
Sbjct: 3038 RSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPKVLQDSLDRCYSTPSGCLELCDSCQP 3097

Query: 241  YSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDHEATGPRLSRELLDEKGPEVLQDSLDRCY 300
            Y S F+ LE+Q+V +AVD+      Q  +ED + + PRLSRELLDEKGPEVLQDSLDRCY
Sbjct: 3098 YRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKGPEVLQDSLDRCY 3157

Query: 301  STPSGCLELTDSCQPYRSAFYVLEQQRVGLAVNMDEIEKYQEVEEDQDPSCPRLSRELLD 360
            STPSGCLEL DSCQPYRSAFY+LEQQRVGLAV+MDEIEKYQEVEEDQDPSCPRLSRELLD
Sbjct: 3158 STPSGCLELCDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLD 3217

Query: 361  EKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEE 420
            EKEPEVLQDSL RCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEE
Sbjct: 3218 EKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEE 3277

Query: 421  DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGF 480
            DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGF
Sbjct: 3278 DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGF 3337

Query: 481  SLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSL 540
            SLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSL
Sbjct: 3338 SLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSL 3397

Query: 541  DRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSG 600
            DRCYSTPSGCLEL DSCQPYRSAFY+LEQQ VGLAVDMDEIEKYQEVEEDQDPSCPRLS 
Sbjct: 3398 DRCYSTPSGCLELCDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSR 3457

Query: 601  ELLDEKEPEVLQESLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEK-- 658
            ELLDEKEPEVLQ+SLDRCYSTPSG LEL D  QPY SA Y LE+Q +GLA+D+D+IEK  
Sbjct: 3458 ELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDKIEKKG 3517

Query: 659  -----------------YQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRCYSTPSGYL 701
                              +E EEDQ+P CPRL+  L++ +E EVLQDSL RCYSTPS Y 
Sbjct: 3518 KGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEREVLQDSLDRCYSTPSMYF 3577

Query: 702  ELPDLGQPYSSAVYSLEEQYLGLALDVD 729
            ELPD  Q Y S  YS EEQ++  AL VD
Sbjct: 3578 ELPDSFQHYRSVFYSFEEQHISFALYVD 3605


>gi|239741309 PREDICTED: hypothetical protein XP_002344485 [Homo
            sapiens]
          Length = 4621

 Score = 1539 bits (3984), Expect = 0.0
 Identities = 776/917 (84%), Positives = 812/917 (88%), Gaps = 38/917 (4%)

Query: 1    MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQA 60
            MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQA
Sbjct: 341  MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQA 400

Query: 61   LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR 120
            LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVE+AEKVQKSSAPR
Sbjct: 401  LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVELAEKVQKSSAPR 460

Query: 121  EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEW 180
            EMQKAEEKEVPEDS EECAIT SNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEW
Sbjct: 461  EMQKAEEKEVPEDSQEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEW 520

Query: 181  EDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYKS 240
            EDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASY+S
Sbjct: 521  EDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQS 580

Query: 241  YSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDHEATGPRLSRELLDEKGPEVLQDSLDRCY 300
            YSSTFHSLEEQQVCMAVDIGRHRWDQVKKED EATGPRLSRELLDEKGPEVLQDSLDRCY
Sbjct: 581  YSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLDRCY 640

Query: 301  STPSGCLELTDSCQPYRSAFYVLEQQRVGLAVNMDEIEKYQEVEEDQDPSCPRLSRELLD 360
            STPSGCLELTDSCQPYRSAFYVLEQQR+GLAV+MDEIEKYQEVEEDQDPSCPRLSRELLD
Sbjct: 641  STPSGCLELTDSCQPYRSAFYVLEQQRIGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLD 700

Query: 361  EKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEE 420
            EKEPEVLQDSL RCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDR KKDQEEEE
Sbjct: 701  EKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEE 760

Query: 421  DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGF 480
            DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGF
Sbjct: 761  DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGF 820

Query: 481  SLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSL 540
            SLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSL
Sbjct: 821  SLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSL 880

Query: 541  DRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSG 600
            DR YSTPSGCLELTDSCQPYRSAFY+LEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLS 
Sbjct: 881  DRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSR 940

Query: 601  ELLDEKEPEVLQESLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQ 660
            ELLDEKEPEVLQ+SLDRCYSTPSG LEL D  QPY SA Y LE+Q +GLA+D+D  +K Q
Sbjct: 941  ELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQ 1000

Query: 661  EVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQ 720
            E EEDQ P CPRLSRELL+  EPEVLQDSL RCYSTPS  LE PD  QPY S+ Y+LEE+
Sbjct: 1001 EEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEK 1060

Query: 721  YLGLALDVDRIKKD-------------------QEEEEDQGPPCPRLSRELLEVVEPEVL 761
            ++G +LDV  I+K                    +E EEDQ PPCPRLSRELL+   PEVL
Sbjct: 1061 HVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVL 1120

Query: 762  QDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSK 821
            QDSLDRCYSTPS CLE  DSCQPY S+FY LE++ VG ++D+ EIEK             
Sbjct: 1121 QDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEK------------- 1167

Query: 822  KERRRGRKEGEEDQNPPCPRLNSMLMEVEEPEVLQDSLDICYSTPSMYFELPDSFQHYRS 881
                   +E EEDQ+P CPRL+  L++ +EPEVLQDSLD CYSTPS Y ELPD  Q Y S
Sbjct: 1168 ------YQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSS 1221

Query: 882  VFYSFEEEHISFALYVD 898
              YS EE+++  AL VD
Sbjct: 1222 AVYSLEEQYLGLALDVD 1238



 Score = 1157 bits (2993), Expect = 0.0
 Identities = 609/843 (72%), Positives = 657/843 (77%), Gaps = 58/843 (6%)

Query: 100  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHR 156
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 2381 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 2440

Query: 157  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 213
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 2441 SAVYSLEEQYLGLALD--------------VDRTKKDQEEEEDQGPPCPRLSRELLEVVE 2486

Query: 214  EEVPQESWDEGYSTLSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIG------------- 260
             EV Q+S D  YST S   E   S + Y S+F++LEE+ V  ++D+G             
Sbjct: 2487 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 2546

Query: 261  ------RHRWDQVKKEDHEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 314
                  R R  +  +ED     PRLSRELLDEKGPEVLQDSLDR YSTPSGCLELTDSCQ
Sbjct: 2547 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQ 2606

Query: 315  PYRSAFYVLEQQRVGLAVNMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRC 374
            PYRSAFYVLEQQRVGLAV+MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL RC
Sbjct: 2607 PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 2666

Query: 375  YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 434
            YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELL
Sbjct: 2667 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 2726

Query: 435  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 494
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 2727 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 2786

Query: 495  KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 554
            KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEK PEVLQDSLDRCYSTPSG LEL 
Sbjct: 2787 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELP 2846

Query: 555  DSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQES 614
            D  QPY SA Y LE+Q +GLA+D+D  +K QE EEDQ P CPRLS ELL+  EPEVLQ+S
Sbjct: 2847 DLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDS 2906

Query: 615  LDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEK---------------- 658
            LDRCYSTPS CLE  DSCQPY S+FY LE++ VG ++D+ EIEK                
Sbjct: 2907 LDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKER 2966

Query: 659  ---YQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVY 715
                +E EEDQ+P CPRLSRELLDEKEPEVLQDSL RCYSTPSGYLELPDLGQPYSSAVY
Sbjct: 2967 RRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVY 3026

Query: 716  SLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSC 775
            SLEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSC
Sbjct: 3027 SLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSC 3086

Query: 776  LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQ 835
            LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQ
Sbjct: 3087 LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQ 3146

Query: 836  NPPCPRLNSMLMEVEEPEVLQDSLDICYSTPSMYFELPDSFQHYRSVFYSFEEEHISFAL 895
            NPPCPRL+  L++ +EPEVLQDSLD CYSTPS Y ELPD  Q Y S  YS EE+++  AL
Sbjct: 3147 NPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 3206

Query: 896  YVD 898
             VD
Sbjct: 3207 DVD 3209



 Score = 1087 bits (2810), Expect = 0.0
 Identities = 577/843 (68%), Positives = 639/843 (75%), Gaps = 74/843 (8%)

Query: 120  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 179
            RE+   +  EV +DSL+ C  T S      DS QP+R      E+ +V   +        
Sbjct: 3812 RELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVD------- 3864

Query: 180  WEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTLSIPPEMLA 236
                   + E E   E EE++ P  PR    L + +E EV Q+S D  YST S   E+  
Sbjct: 3865 -------MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPD 3917

Query: 237  SYKSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDHEATGPRLSRELLDEKGPEVLQDSL 296
              + YSS  +SLEEQ + +A+D+ R + DQ ++ED     PRLSRELL+   PEVLQDSL
Sbjct: 3918 LGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSL 3977

Query: 297  DRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVNMDEIEKY---------------- 340
            DRCYSTPS CLE  DSCQPY S+FY LE++ VG ++++ EIEK                 
Sbjct: 3978 DRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERR 4037

Query: 341  ---QEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYS 397
               +E EEDQ P CPRLSRELLDEK PEVLQDSL RCYSTPSG LEL D  QPY SA Y 
Sbjct: 4038 RGRKEGEEDQTPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYV 4097

Query: 398  LEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL 457
            LE+Q +GLA+D+D I+K QE EEDQ P CPRLSRELL+  EPEVLQDSLDRCYSTPS  L
Sbjct: 4098 LEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYL 4157

Query: 458  EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQN 517
            E PD  QPY S+ Y+LEE+++G +LDV               R+KK++     E EEDQ 
Sbjct: 4158 ELPDLGQPYSSAVYSLEEQYLGLALDVD--------------RTKKDQ-----EEEEDQG 4198

Query: 518  PPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVD 577
            PPCPRLSRELL+   PEVLQDSLDRCYSTPS CLE  DSCQPY S+FY LE++ VG ++D
Sbjct: 4199 PPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLD 4258

Query: 578  MDEIEKY-------------------QEVEEDQDPSCPRLSGELLDEKEPEVLQESLDRC 618
            + EIEK                    +E EEDQ+P CPRLS ELLDEK PEVLQ+SLDRC
Sbjct: 4259 VGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRC 4318

Query: 619  YSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELL 678
            YSTPSGCLELTDSCQPYRSAFY+LEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELL
Sbjct: 4319 YSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELL 4378

Query: 679  DEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEE 738
            DEKEPEVLQDSL RCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDR KKDQEEE
Sbjct: 4379 DEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEE 4438

Query: 739  EDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVG 798
            EDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVG
Sbjct: 4439 EDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVG 4498

Query: 799  FSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNSMLMEVEEPEVLQDS 858
            FSLDVGEIEKKGKGKKRRGRRSKK+RRRGRKEGEEDQNPPCPRLN +LMEVEEPEVLQDS
Sbjct: 4499 FSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQNPPCPRLNGVLMEVEEPEVLQDS 4558

Query: 859  LDICYSTPSMYFELPDSFQHYRSVFYSFEEEHISFALYVDNRFFTLTVTSLHLVFQMGVI 918
            LD CYSTPSMYFELPDSFQHYRSVFYSFEE+HISFALYVDNRFFTLTVTSLHLVFQMGVI
Sbjct: 4559 LDGCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYVDNRFFTLTVTSLHLVFQMGVI 4618

Query: 919  FPQ 921
            FPQ
Sbjct: 4619 FPQ 4621



 Score = 1061 bits (2745), Expect = 0.0
 Identities = 567/843 (67%), Positives = 625/843 (74%), Gaps = 77/843 (9%)

Query: 100  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHR 156
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 3376 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 3435

Query: 157  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 213
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 3436 SAVYSLEEQYLGLALD--------------VDRTKKDQEEEEDQGPPCPRLSRELLEVVE 3481

Query: 214  EEVPQESWDEGYSTLSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIG------------- 260
             EV Q+S D  YST S   E   S + Y S+F++LEE+ V  ++D+G             
Sbjct: 3482 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 3541

Query: 261  ------RHRWDQVKKEDHEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 314
                  R R  +  +ED     PRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 3542 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 3601

Query: 315  PYRSAFYVLEQQRVGLAVNMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRC 374
            PYRSAFYVLEQQRVGLAV+MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL RC
Sbjct: 3602 PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 3661

Query: 375  YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 434
            YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELL
Sbjct: 3662 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 3721

Query: 435  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 494
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 3722 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 3781

Query: 495  KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 554
            KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT
Sbjct: 3782 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 3841

Query: 555  DSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQES 614
            DSCQPYRSAFY+LEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLS ELLDEKEPEVLQ+S
Sbjct: 3842 DSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDS 3901

Query: 615  LDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLS 674
            LDRCYSTPSG LEL D  QPY SA Y LE+Q +GLA+D+D  +K QE EEDQ P CPRLS
Sbjct: 3902 LDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLS 3961

Query: 675  RELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKD 734
            RELL+  EPEVLQDSL RCYSTPS  LE PD  QPY S+ Y+LEE+++G +LDV  I+K 
Sbjct: 3962 RELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKK 4021

Query: 735  -------------------QEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSC 775
                               +E EEDQ PPCPRLSRELL+   PEVLQDSLDRCYSTPS C
Sbjct: 4022 GKGKKRRGRRSKKERRRGRKEGEEDQTPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGC 4081

Query: 776  LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQ 835
            LE  DSCQPY S+FY LE++ VG ++D+ EIEK                    +E EEDQ
Sbjct: 4082 LELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEK-------------------YQEVEEDQ 4122

Query: 836  NPPCPRLNSMLMEVEEPEVLQDSLDICYSTPSMYFELPDSFQHYRSVFYSFEEEHISFAL 895
            +P CPRL+  L++ +EPEVLQDSLD CYSTPS Y ELPD  Q Y S  YS EE+++  AL
Sbjct: 4123 DPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 4182

Query: 896  YVD 898
             VD
Sbjct: 4183 DVD 4185



 Score = 1060 bits (2741), Expect = 0.0
 Identities = 566/843 (67%), Positives = 624/843 (74%), Gaps = 77/843 (9%)

Query: 100  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHR 156
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 3620 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 3679

Query: 157  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 213
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 3680 SAVYSLEEQYLGLALD--------------VDRTKKDQEEEEDQGPPCPRLSRELLEVVE 3725

Query: 214  EEVPQESWDEGYSTLSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIG------------- 260
             EV Q+S D  YST S   E   S + Y S+F++LEE+ V  ++D+G             
Sbjct: 3726 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 3785

Query: 261  ------RHRWDQVKKEDHEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 314
                  R R  +  +ED     PRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 3786 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 3845

Query: 315  PYRSAFYVLEQQRVGLAVNMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRC 374
            PYRSAFYVLEQQRVGLAV+MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL RC
Sbjct: 3846 PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 3905

Query: 375  YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 434
            YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELL
Sbjct: 3906 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 3965

Query: 435  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 494
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 3966 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 4025

Query: 495  KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 554
            KRRGRRSKKERRRGRKEGEEDQ PPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT
Sbjct: 4026 KRRGRRSKKERRRGRKEGEEDQTPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 4085

Query: 555  DSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQES 614
            DSCQPYRSAFY+LEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLS ELLDEKEPEVLQ+S
Sbjct: 4086 DSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDS 4145

Query: 615  LDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLS 674
            LDRCYSTPSG LEL D  QPY SA Y LE+Q +GLA+D+D  +K QE EEDQ P CPRLS
Sbjct: 4146 LDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLS 4205

Query: 675  RELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKD 734
            RELL+  EPEVLQDSL RCYSTPS  LE PD  QPY S+ Y+LEE+++G +LDV  I+K 
Sbjct: 4206 RELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKK 4265

Query: 735  -------------------QEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSC 775
                               +E EEDQ PPCPRLSRELL+   PEVLQDSLDRCYSTPS C
Sbjct: 4266 GKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGC 4325

Query: 776  LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQ 835
            LE  DSCQPY S+FY LE++ VG ++D+ EIEK                    +E EEDQ
Sbjct: 4326 LELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEK-------------------YQEVEEDQ 4366

Query: 836  NPPCPRLNSMLMEVEEPEVLQDSLDICYSTPSMYFELPDSFQHYRSVFYSFEEEHISFAL 895
            +P CPRL+  L++ +EPEVLQDSLD CYSTPS Y ELPD  Q Y S  YS EE+++  AL
Sbjct: 4367 DPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 4426

Query: 896  YVD 898
             VD
Sbjct: 4427 DVD 4429



 Score = 1058 bits (2737), Expect = 0.0
 Identities = 566/843 (67%), Positives = 624/843 (74%), Gaps = 77/843 (9%)

Query: 100  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHR 156
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 917  DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 976

Query: 157  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 213
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 977  SAVYSLEEQYLGLALD--------------VDRTKKDQEEEEDQGPPCPRLSRELLEVVE 1022

Query: 214  EEVPQESWDEGYSTLSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIG------------- 260
             EV Q+S D  YST S   E   S + Y S+F++LEE+ V  ++D+G             
Sbjct: 1023 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 1082

Query: 261  ------RHRWDQVKKEDHEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 314
                  R R  +  +ED     PRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 1083 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 1142

Query: 315  PYRSAFYVLEQQRVGLAVNMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRC 374
            PYRSAFYVLEQQRVGLAV+MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL RC
Sbjct: 1143 PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 1202

Query: 375  YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 434
            YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELL
Sbjct: 1203 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 1262

Query: 435  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 494
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 1263 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 1322

Query: 495  KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 554
            KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDR YSTPSGCLELT
Sbjct: 1323 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELT 1382

Query: 555  DSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQES 614
            DSCQPYRSAFY+LEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLS ELLDEKEPEVLQ+S
Sbjct: 1383 DSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDS 1442

Query: 615  LDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLS 674
            LDRCYSTPSG LEL D  QPY SA Y LE+Q +GLA+D+D  +K QE EEDQ P CPRLS
Sbjct: 1443 LDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLS 1502

Query: 675  RELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKD 734
            RELL+  EPEVLQDSL RCYSTPS  LE PD  QPY S+ Y+LEE+++G +LDV  I+K 
Sbjct: 1503 RELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKK 1562

Query: 735  -------------------QEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSC 775
                               +E EEDQ PPCPRLSRELL+   PEVLQDSLDRCYSTPS C
Sbjct: 1563 GKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGC 1622

Query: 776  LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQ 835
            LE  DSCQPY S+FY LE++ VG ++D+ EIEK                    +E EEDQ
Sbjct: 1623 LELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEK-------------------YQEVEEDQ 1663

Query: 836  NPPCPRLNSMLMEVEEPEVLQDSLDICYSTPSMYFELPDSFQHYRSVFYSFEEEHISFAL 895
            +P CPRL+  L++ +EPEVLQDSLD CYSTPS Y ELPD  Q Y S  YS EE+++  AL
Sbjct: 1664 DPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 1723

Query: 896  YVD 898
             VD
Sbjct: 1724 DVD 1726



 Score = 1058 bits (2735), Expect = 0.0
 Identities = 560/820 (68%), Positives = 615/820 (75%), Gaps = 74/820 (9%)

Query: 120  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 179
            RE+   +E EV +DSL+ C  T S      D  QP+     + EE  +   L        
Sbjct: 3155 RELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALD------- 3207

Query: 180  WEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTLSIPPEMLA 236
                   +   + D EEEE++GP  PR    L E  E EV Q+S D  YST S   E   
Sbjct: 3208 -------VDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPD 3260

Query: 237  SYKSYSSTFHSLEEQQVCMAVDIG-------------------RHRWDQVKKEDHEATGP 277
            S + Y S+F++LEE+ V  ++D+G                   R R  +  +ED     P
Sbjct: 3261 SCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCP 3320

Query: 278  RLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVNMDEI 337
            RLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAV+MDEI
Sbjct: 3321 RLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEI 3380

Query: 338  EKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYS 397
            EKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL RCYSTPSGYLELPDLGQPYSSAVYS
Sbjct: 3381 EKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYS 3440

Query: 398  LEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL 457
            LEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL
Sbjct: 3441 LEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL 3500

Query: 458  EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQN 517
            EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQN
Sbjct: 3501 EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQN 3560

Query: 518  PPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVD 577
            PPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFY+LEQQRVGLAVD
Sbjct: 3561 PPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVD 3620

Query: 578  MDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQESLDRCYSTPSGCLELTDSCQPYRS 637
            MDEIEKYQEVEEDQDPSCPRLS ELLDEKEPEVLQ+SLDRCYSTPSG LEL D  QPY S
Sbjct: 3621 MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSS 3680

Query: 638  AFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRCYSTP 697
            A Y LE+Q +GLA+D+D  +K QE EEDQ P CPRLSRELL+  EPEVLQDSL RCYSTP
Sbjct: 3681 AVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTP 3740

Query: 698  SGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKD-------------------QEEE 738
            S  LE PD  QPY S+ Y+LEE+++G +LDV  I+K                    +E E
Sbjct: 3741 SSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGE 3800

Query: 739  EDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVG 798
            EDQ PPCPRLSRELL+   PEVLQDSLDRCYSTPS CLE  DSCQPY S+FY LE++ VG
Sbjct: 3801 EDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVG 3860

Query: 799  FSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNSMLMEVEEPEVLQDS 858
             ++D+ EIEK                    +E EEDQ+P CPRL+  L++ +EPEVLQDS
Sbjct: 3861 LAVDMDEIEK-------------------YQEVEEDQDPSCPRLSRELLDEKEPEVLQDS 3901

Query: 859  LDICYSTPSMYFELPDSFQHYRSVFYSFEEEHISFALYVD 898
            LD CYSTPS Y ELPD  Q Y S  YS EE+++  AL VD
Sbjct: 3902 LDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD 3941



 Score = 1055 bits (2727), Expect = 0.0
 Identities = 565/843 (67%), Positives = 623/843 (73%), Gaps = 77/843 (9%)

Query: 100  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHR 156
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 673  DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 732

Query: 157  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 213
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 733  SAVYSLEEQYLGLALD--------------VDRTKKDQEEEEDQGPPCPRLSRELLEVVE 778

Query: 214  EEVPQESWDEGYSTLSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIG------------- 260
             EV Q+S D  YST S   E   S + Y S+F++LEE+ V  ++D+G             
Sbjct: 779  PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 838

Query: 261  ------RHRWDQVKKEDHEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 314
                  R R  +  +ED     PRLSRELLDEKGPEVLQDSLDR YSTPSGCLELTDSCQ
Sbjct: 839  RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQ 898

Query: 315  PYRSAFYVLEQQRVGLAVNMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRC 374
            PYRSAFYVLEQQRVGLAV+MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL RC
Sbjct: 899  PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 958

Query: 375  YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 434
            YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELL
Sbjct: 959  YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 1018

Query: 435  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 494
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 1019 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 1078

Query: 495  KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 554
            KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT
Sbjct: 1079 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 1138

Query: 555  DSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQES 614
            DSCQPYRSAFY+LEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLS ELLDEKEPEVLQ+S
Sbjct: 1139 DSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDS 1198

Query: 615  LDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLS 674
            LDRCYSTPSG LEL D  QPY SA Y LE+Q +GLA+D+D  +K QE EEDQ P CPRLS
Sbjct: 1199 LDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLS 1258

Query: 675  RELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKD 734
            RELL+  EPEVLQDSL RCYSTPS  LE PD  QPY S+ Y+LEE+++G +LDV  I+K 
Sbjct: 1259 RELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKK 1318

Query: 735  -------------------QEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSC 775
                               +E EEDQ PPCPRLSRELL+   PEVLQDSLDR YSTPS C
Sbjct: 1319 GKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGC 1378

Query: 776  LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQ 835
            LE  DSCQPY S+FY LE++ VG ++D+ EIEK                    +E EEDQ
Sbjct: 1379 LELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEK-------------------YQEVEEDQ 1419

Query: 836  NPPCPRLNSMLMEVEEPEVLQDSLDICYSTPSMYFELPDSFQHYRSVFYSFEEEHISFAL 895
            +P CPRL+  L++ +EPEVLQDSLD CYSTPS Y ELPD  Q Y S  YS EE+++  AL
Sbjct: 1420 DPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 1479

Query: 896  YVD 898
             VD
Sbjct: 1480 DVD 1482



 Score = 1055 bits (2727), Expect = 0.0
 Identities = 565/843 (67%), Positives = 623/843 (73%), Gaps = 77/843 (9%)

Query: 100  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHR 156
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 1161 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 1220

Query: 157  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 213
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 1221 SAVYSLEEQYLGLALD--------------VDRTKKDQEEEEDQGPPCPRLSRELLEVVE 1266

Query: 214  EEVPQESWDEGYSTLSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIG------------- 260
             EV Q+S D  YST S   E   S + Y S+F++LEE+ V  ++D+G             
Sbjct: 1267 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 1326

Query: 261  ------RHRWDQVKKEDHEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 314
                  R R  +  +ED     PRLSRELLDEKGPEVLQDSLDR YSTPSGCLELTDSCQ
Sbjct: 1327 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQ 1386

Query: 315  PYRSAFYVLEQQRVGLAVNMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRC 374
            PYRSAFYVLEQQRVGLAV+MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL RC
Sbjct: 1387 PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 1446

Query: 375  YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 434
            YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELL
Sbjct: 1447 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 1506

Query: 435  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 494
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 1507 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 1566

Query: 495  KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 554
            KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT
Sbjct: 1567 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 1626

Query: 555  DSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQES 614
            DSCQPYRSAFY+LEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLS ELLDEKEPEVLQ+S
Sbjct: 1627 DSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDS 1686

Query: 615  LDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLS 674
            LDRCYSTPSG LEL D  QPY SA Y LE+Q +GLA+D+D  +K QE EEDQ P CPRLS
Sbjct: 1687 LDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLS 1746

Query: 675  RELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKD 734
            RELL+  EPEVLQDSL RCYSTPS  LE PD  QPY S+ Y+LEE+++G +LDV  I+K 
Sbjct: 1747 RELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKK 1806

Query: 735  -------------------QEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSC 775
                               +E EEDQ PPCPRLSRELL+   PEVLQDSLDR YSTPS C
Sbjct: 1807 GKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGC 1866

Query: 776  LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQ 835
            LE  DSCQPY S+FY LE++ VG ++D+ EIEK                    +E EEDQ
Sbjct: 1867 LELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEK-------------------YQEVEEDQ 1907

Query: 836  NPPCPRLNSMLMEVEEPEVLQDSLDICYSTPSMYFELPDSFQHYRSVFYSFEEEHISFAL 895
            +P CPRL+  L++ +EPEVLQDSLD CYSTPS Y ELPD  Q Y S  YS EE+++  AL
Sbjct: 1908 DPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 1967

Query: 896  YVD 898
             VD
Sbjct: 1968 DVD 1970



 Score = 1055 bits (2727), Expect = 0.0
 Identities = 565/843 (67%), Positives = 623/843 (73%), Gaps = 77/843 (9%)

Query: 100  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHR 156
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 1405 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 1464

Query: 157  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 213
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 1465 SAVYSLEEQYLGLALD--------------VDRTKKDQEEEEDQGPPCPRLSRELLEVVE 1510

Query: 214  EEVPQESWDEGYSTLSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIG------------- 260
             EV Q+S D  YST S   E   S + Y S+F++LEE+ V  ++D+G             
Sbjct: 1511 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 1570

Query: 261  ------RHRWDQVKKEDHEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 314
                  R R  +  +ED     PRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 1571 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 1630

Query: 315  PYRSAFYVLEQQRVGLAVNMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRC 374
            PYRSAFYVLEQQRVGLAV+MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL RC
Sbjct: 1631 PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 1690

Query: 375  YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 434
            YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELL
Sbjct: 1691 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 1750

Query: 435  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 494
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 1751 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 1810

Query: 495  KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 554
            KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDR YSTPSGCLELT
Sbjct: 1811 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELT 1870

Query: 555  DSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQES 614
            DSCQPYRSAFY+LEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLS ELLDEKEPEVLQ+S
Sbjct: 1871 DSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDS 1930

Query: 615  LDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLS 674
            LDRCYSTPSG LEL D  QPY SA Y LE+Q +GLA+D+D  +K QE EEDQ P CPRLS
Sbjct: 1931 LDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLS 1990

Query: 675  RELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKD 734
            RELL+  EPEVLQDSL RCYSTPS  LE PD  QPY S+ Y+LEE+++G +LDV  I+K 
Sbjct: 1991 RELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKK 2050

Query: 735  -------------------QEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSC 775
                               +E EEDQ PPCPRLSRELL+   PEVLQDSLDR YSTPS C
Sbjct: 2051 GKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGC 2110

Query: 776  LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQ 835
            LE  DSCQPY S+FY LE++ VG ++D+ EIEK                    +E EEDQ
Sbjct: 2111 LELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEK-------------------YQEVEEDQ 2151

Query: 836  NPPCPRLNSMLMEVEEPEVLQDSLDICYSTPSMYFELPDSFQHYRSVFYSFEEEHISFAL 895
            +P CPRL+  L++ +EPEVLQDSLD CYSTPS Y ELPD  Q Y S  YS EE+++  AL
Sbjct: 2152 DPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 2211

Query: 896  YVD 898
             VD
Sbjct: 2212 DVD 2214



 Score = 1051 bits (2719), Expect = 0.0
 Identities = 566/842 (67%), Positives = 624/842 (74%), Gaps = 77/842 (9%)

Query: 100  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHR 156
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 2137 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 2196

Query: 157  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 213
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 2197 SAVYSLEEQYLGLALD--------------VDRTKKDQEEEEDQGPPCPRLSRELLEVVE 2242

Query: 214  EEVPQESWDEGYSTLSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIG------------- 260
             EV Q+S D  YST S   E   S + Y S+F++LEE+ V  ++D+G             
Sbjct: 2243 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 2302

Query: 261  ------RHRWDQVKKEDHEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 314
                  R R  +  +ED     PRLSRELLDEKGPEVLQDSLDR YSTPSGCLELTDSCQ
Sbjct: 2303 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQ 2362

Query: 315  PYRSAFYVLEQQRVGLAVNMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRC 374
            PYRSAFYVLEQQRVGLAV+MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL RC
Sbjct: 2363 PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 2422

Query: 375  YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 434
            YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELL
Sbjct: 2423 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 2482

Query: 435  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 494
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 2483 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 2542

Query: 495  KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 554
            KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDR YSTPSGCLELT
Sbjct: 2543 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELT 2602

Query: 555  DSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQES 614
            DSCQPYRSAFY+LEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLS ELLDEKEPEVLQ+S
Sbjct: 2603 DSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDS 2662

Query: 615  LDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLS 674
            LDRCYSTPSG LEL D  QPY SA Y LE+Q +GLA+D+D  +K QE EEDQ P CPRLS
Sbjct: 2663 LDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLS 2722

Query: 675  RELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKD 734
            RELL+  EPEVLQDSL RCYSTPS  LE PD  QPY S+ Y+LEE+++G +LDV  I+K 
Sbjct: 2723 RELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKK 2782

Query: 735  -------------------QEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSC 775
                               +E EEDQ PPCPRLSRELL+  EPEVLQDSLDRCYSTPS  
Sbjct: 2783 GKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGY 2842

Query: 776  LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQ 835
            LE PD  QPY S+ Y+LEE+++G +LDV               R+KK+     +E EEDQ
Sbjct: 2843 LELPDLGQPYSSAVYSLEEQYLGLALDVD--------------RTKKD-----QEEEEDQ 2883

Query: 836  NPPCPRLNSMLMEVEEPEVLQDSLDICYSTPSMYFELPDSFQHYRSVFYSFEEEHISFAL 895
             PPCPRL+  L+EV EPEVLQDSLD CYSTPS   E PDS Q Y S FY+ EE+H+ F+L
Sbjct: 2884 GPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSL 2943

Query: 896  YV 897
             V
Sbjct: 2944 DV 2945



 Score = 1051 bits (2717), Expect = 0.0
 Identities = 564/843 (66%), Positives = 622/843 (73%), Gaps = 77/843 (9%)

Query: 100  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHR 156
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 1649 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 1708

Query: 157  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 213
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 1709 SAVYSLEEQYLGLALD--------------VDRTKKDQEEEEDQGPPCPRLSRELLEVVE 1754

Query: 214  EEVPQESWDEGYSTLSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIG------------- 260
             EV Q+S D  YST S   E   S + Y S+F++LEE+ V  ++D+G             
Sbjct: 1755 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 1814

Query: 261  ------RHRWDQVKKEDHEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 314
                  R R  +  +ED     PRLSRELLDEKGPEVLQDSLDR YSTPSGCLELTDSCQ
Sbjct: 1815 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQ 1874

Query: 315  PYRSAFYVLEQQRVGLAVNMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRC 374
            PYRSAFYVLEQQRVGLAV+MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL RC
Sbjct: 1875 PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 1934

Query: 375  YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 434
            YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELL
Sbjct: 1935 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 1994

Query: 435  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 494
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 1995 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 2054

Query: 495  KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 554
            KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDR YSTPSGCLELT
Sbjct: 2055 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELT 2114

Query: 555  DSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQES 614
            DSCQPYRSAFY+LEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLS ELLDEKEPEVLQ+S
Sbjct: 2115 DSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDS 2174

Query: 615  LDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLS 674
            LDRCYSTPSG LEL D  QPY SA Y LE+Q +GLA+D+D  +K QE EEDQ P CPRLS
Sbjct: 2175 LDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLS 2234

Query: 675  RELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKD 734
            RELL+  EPEVLQDSL RCYSTPS  LE PD  QPY S+ Y+LEE+++G +LDV  I+K 
Sbjct: 2235 RELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKK 2294

Query: 735  -------------------QEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSC 775
                               +E EEDQ PPCPRLSRELL+   PEVLQDSLDR YSTPS C
Sbjct: 2295 GKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGC 2354

Query: 776  LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQ 835
            LE  DSCQPY S+FY LE++ VG ++D+ EIEK                    +E EEDQ
Sbjct: 2355 LELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEK-------------------YQEVEEDQ 2395

Query: 836  NPPCPRLNSMLMEVEEPEVLQDSLDICYSTPSMYFELPDSFQHYRSVFYSFEEEHISFAL 895
            +P CPRL+  L++ +EPEVLQDSLD CYSTPS Y ELPD  Q Y S  YS EE+++  AL
Sbjct: 2396 DPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 2455

Query: 896  YVD 898
             VD
Sbjct: 2456 DVD 2458



 Score = 1051 bits (2717), Expect = 0.0
 Identities = 564/843 (66%), Positives = 622/843 (73%), Gaps = 77/843 (9%)

Query: 100  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHR 156
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 1893 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 1952

Query: 157  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 213
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 1953 SAVYSLEEQYLGLALD--------------VDRTKKDQEEEEDQGPPCPRLSRELLEVVE 1998

Query: 214  EEVPQESWDEGYSTLSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIG------------- 260
             EV Q+S D  YST S   E   S + Y S+F++LEE+ V  ++D+G             
Sbjct: 1999 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 2058

Query: 261  ------RHRWDQVKKEDHEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 314
                  R R  +  +ED     PRLSRELLDEKGPEVLQDSLDR YSTPSGCLELTDSCQ
Sbjct: 2059 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQ 2118

Query: 315  PYRSAFYVLEQQRVGLAVNMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRC 374
            PYRSAFYVLEQQRVGLAV+MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL RC
Sbjct: 2119 PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 2178

Query: 375  YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 434
            YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELL
Sbjct: 2179 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 2238

Query: 435  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 494
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 2239 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 2298

Query: 495  KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 554
            KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDR YSTPSGCLELT
Sbjct: 2299 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELT 2358

Query: 555  DSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQES 614
            DSCQPYRSAFY+LEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLS ELLDEKEPEVLQ+S
Sbjct: 2359 DSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDS 2418

Query: 615  LDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLS 674
            LDRCYSTPSG LEL D  QPY SA Y LE+Q +GLA+D+D  +K QE EEDQ P CPRLS
Sbjct: 2419 LDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLS 2478

Query: 675  RELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKD 734
            RELL+  EPEVLQDSL RCYSTPS  LE PD  QPY S+ Y+LEE+++G +LDV  I+K 
Sbjct: 2479 RELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKK 2538

Query: 735  -------------------QEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSC 775
                               +E EEDQ PPCPRLSRELL+   PEVLQDSLDR YSTPS C
Sbjct: 2539 GKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGC 2598

Query: 776  LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQ 835
            LE  DSCQPY S+FY LE++ VG ++D+ EIEK                    +E EEDQ
Sbjct: 2599 LELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEK-------------------YQEVEEDQ 2639

Query: 836  NPPCPRLNSMLMEVEEPEVLQDSLDICYSTPSMYFELPDSFQHYRSVFYSFEEEHISFAL 895
            +P CPRL+  L++ +EPEVLQDSLD CYSTPS Y ELPD  Q Y S  YS EE+++  AL
Sbjct: 2640 DPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 2699

Query: 896  YVD 898
             VD
Sbjct: 2700 DVD 2702



 Score = 1003 bits (2592), Expect = 0.0
 Identities = 536/825 (64%), Positives = 606/825 (73%), Gaps = 65/825 (7%)

Query: 120  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 179
            RE+ +  E EV +DSL+ C  T S+     DS QP+  +    EE  V  +L       +
Sbjct: 2892 RELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKK 2951

Query: 180  WEDAVHIIPENESD-----DEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTLSIP 231
             +        ++ +      E EE++ P  PR    L + +E EV Q+S D  YST S  
Sbjct: 2952 GKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGY 3011

Query: 232  PEMLASYKSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDHEATGPRLSRELLDEKGPEV 291
             E+    + YSS  +SLEEQ + +A+D+ R + DQ ++ED     PRLSRELL+   PEV
Sbjct: 3012 LELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEV 3071

Query: 292  LQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVNMDEIEKY----------- 340
            LQDSLDRCYSTPS CLE  DSCQPY S+FY LE++ VG ++++ EIEK            
Sbjct: 3072 LQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRS 3131

Query: 341  --------QEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYS 392
                    +E EEDQ+P CPRLSRELLDEKEPEVLQDSL RCYSTPSGYLELPDLGQPYS
Sbjct: 3132 KKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 3191

Query: 393  SAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYST 452
            SAVYSLEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYST
Sbjct: 3192 SAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYST 3251

Query: 453  PSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEG 512
            PSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEG
Sbjct: 3252 PSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEG 3311

Query: 513  EEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRV 572
            EEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFY+LEQQRV
Sbjct: 3312 EEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRV 3371

Query: 573  GLAVDMDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQESLDRCYSTPSGCLELTDSC 632
            GLAVDMDEIEKYQEVEEDQDPSCPRLS ELLDEKEPEVLQ+SLDRCYSTPSG LEL D  
Sbjct: 3372 GLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLG 3431

Query: 633  QPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGR 692
            QPY SA Y LE+Q +GLA+D+D  +K QE EEDQ P CPRLSRELL+  EPEVLQDSL R
Sbjct: 3432 QPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDR 3491

Query: 693  CYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKD------------------ 734
            CYSTPS  LE PD  QPY S+ Y+LEE+++G +LDV  I+K                   
Sbjct: 3492 CYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRG 3551

Query: 735  -QEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALE 793
             +E EEDQ PPCPRLSRELL+   PEVLQDSLDRCYSTPS CLE  DSCQPY S+FY LE
Sbjct: 3552 RKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLE 3611

Query: 794  EKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNSMLMEVEEPE 853
            ++ VG ++D+ EIEK                    +E EEDQ+P CPRL+  L++ +EPE
Sbjct: 3612 QQRVGLAVDMDEIEK-------------------YQEVEEDQDPSCPRLSRELLDEKEPE 3652

Query: 854  VLQDSLDICYSTPSMYFELPDSFQHYRSVFYSFEEEHISFALYVD 898
            VLQDSLD CYSTPS Y ELPD  Q Y S  YS EE+++  AL VD
Sbjct: 3653 VLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD 3697



 Score =  969 bits (2504), Expect = 0.0
 Identities = 516/748 (68%), Positives = 564/748 (75%), Gaps = 58/748 (7%)

Query: 100  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHR 156
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 3864 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 3923

Query: 157  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 213
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 3924 SAVYSLEEQYLGLALD--------------VDRTKKDQEEEEDQGPPCPRLSRELLEVVE 3969

Query: 214  EEVPQESWDEGYSTLSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIG------------- 260
             EV Q+S D  YST S   E   S + Y S+F++LEE+ V  ++D+G             
Sbjct: 3970 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 4029

Query: 261  ------RHRWDQVKKEDHEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 314
                  R R  +  +ED     PRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 4030 RRSKKERRRGRKEGEEDQTPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 4089

Query: 315  PYRSAFYVLEQQRVGLAVNMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRC 374
            PYRSAFYVLEQQRVGLAV+MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL RC
Sbjct: 4090 PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 4149

Query: 375  YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 434
            YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELL
Sbjct: 4150 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 4209

Query: 435  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 494
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 4210 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 4269

Query: 495  KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 554
            KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT
Sbjct: 4270 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 4329

Query: 555  DSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQES 614
            DSCQPYRSAFY+LEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLS ELLDEKEPEVLQ+S
Sbjct: 4330 DSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDS 4389

Query: 615  LDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLS 674
            LDRCYSTPSG LEL D  QPY SA Y LE+Q +GLA+D+D  +K QE EEDQ P CPRLS
Sbjct: 4390 LDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLS 4449

Query: 675  RELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKD 734
            RELL+  EPEVLQDSL RCYSTPS  LE PD  QPY S+ Y+LEE+++G +LDV  I+K 
Sbjct: 4450 RELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKK 4509

Query: 735  -------------------QEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSC 775
                               +E EEDQ PPCPRL+  L+EV EPEVLQDSLD CYSTPS  
Sbjct: 4510 GKGKKRRGRRSKKKRRRGRKEGEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMY 4569

Query: 776  LEQPDSCQPYGSSFYALEEKHVGFSLDV 803
             E PDS Q Y S FY+ EE+H+ F+L V
Sbjct: 4570 FELPDSFQHYRSVFYSFEEQHISFALYV 4597



 Score =  861 bits (2225), Expect = 0.0
 Identities = 516/981 (52%), Positives = 604/981 (61%), Gaps = 139/981 (14%)

Query: 1   MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQA 60
           MLRNERQFKEEKLAEQLKQAEELRQYKVLVH+QERELTQLREKLREGRDASRSLNEHLQA
Sbjct: 70  MLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQA 129

Query: 61  LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR 120
           LLT DEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPEND D+DEDVQVE AEKVQKSSAPR
Sbjct: 130 LLTLDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAEKVQKSSAPR 189

Query: 121 EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLI--GSSSHV 178
           E+QK EE +VPEDSLEECAITCSNSHGP DSNQPH+  KITFEED+V+STL+    SSH 
Sbjct: 190 EVQKTEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTLVVDRESSHD 249

Query: 179 EWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASY 238
           E +DA++I+P            GP S            P  S     + L I  ++    
Sbjct: 250 ECQDALNILP----------VPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLHPQL 299

Query: 239 KSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDHEATGPRLSRELLDEKG---------- 288
                 F +L+E+  C    +     +Q KK  +E     +   L +E+           
Sbjct: 300 AEKKQQFRNLKER--CFVTQLAGFLANQQKKYKYEECKDLIKSMLRNERQFKEEKLAEQL 357

Query: 289 -----------------------PEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQ 325
                                   E L++  D   S       L    +P +S    L++
Sbjct: 358 KQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQE 417

Query: 326 QRV---GLAVNM------------DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDS 370
           Q      LA ++            DE  + +  E+ Q  S P   RE+   +E EV +DS
Sbjct: 418 QLAEGCRLAQHLVQKLSPENDNDDDEDVQVELAEKVQKSSAP---REMQKAEEKEVPEDS 474

Query: 371 LGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL--------------DVDRIKKDQ 416
              C  T S      D  QP+     + EE  +   L               +   + D 
Sbjct: 475 QEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDD 534

Query: 417 EEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEK 476
           EEEE++GP  P   R L E  E EV Q+S D  YST S   E   S Q Y S+F++LEE+
Sbjct: 535 EEEEEKGPVSP---RNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQ 591

Query: 477 HVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVL 536
            V  ++D+G                   R R  +  +EDQ    PRLSRELLDEKGPEVL
Sbjct: 592 QVCMAVDIG-------------------RHRWDQVKKEDQEATGPRLSRELLDEKGPEVL 632

Query: 537 QDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCP 596
           QDSLDRCYSTPSGCLELTDSCQPYRSAFY+LEQQR+GLAVDMDEIEKYQEVEEDQDPSCP
Sbjct: 633 QDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRIGLAVDMDEIEKYQEVEEDQDPSCP 692

Query: 597 RLSGELLDEKEPEVLQESLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEI 656
           RLS ELLDEKEPEVLQ+SLDRCYSTPSG LEL D  QPY SA Y LE+Q +GLA+D+D  
Sbjct: 693 RLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRT 752

Query: 657 EKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYS 716
           +K QE EEDQ P CPRLSRELL+  EPEVLQDSL RCYSTPS  LE PD  QPY S+ Y+
Sbjct: 753 KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYA 812

Query: 717 LEEQYLGLALDVDRIKKD-------------------QEEEEDQGPPCPRLSRELLEVVE 757
           LEE+++G +LDV  I+K                    +E EEDQ PPCPRLSRELL+   
Sbjct: 813 LEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKG 872

Query: 758 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 817
           PEVLQDSLDR YSTPS CLE  DSCQPY S+FY LE++ VG ++D+ EIEK         
Sbjct: 873 PEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEK--------- 923

Query: 818 RRSKKERRRGRKEGEEDQNPPCPRLNSMLMEVEEPEVLQDSLDICYSTPSMYFELPDSFQ 877
                      +E EEDQ+P CPRL+  L++ +EPEVLQDSLD CYSTPS Y ELPD  Q
Sbjct: 924 ----------YQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQ 973

Query: 878 HYRSVFYSFEEEHISFALYVD 898
            Y S  YS EE+++  AL VD
Sbjct: 974 PYSSAVYSLEEQYLGLALDVD 994


>gi|169162915 PREDICTED: hypothetical protein LOC728841 [Homo
           sapiens]
          Length = 3815

 Score = 1539 bits (3984), Expect = 0.0
 Identities = 777/917 (84%), Positives = 813/917 (88%), Gaps = 38/917 (4%)

Query: 1   MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQA 60
           MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQA
Sbjct: 90  MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQA 149

Query: 61  LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR 120
           LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVE+AEKVQKSSAPR
Sbjct: 150 LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVELAEKVQKSSAPR 209

Query: 121 EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEW 180
           EMQKAEEKEVPEDS EECAIT SNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEW
Sbjct: 210 EMQKAEEKEVPEDSQEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEW 269

Query: 181 EDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYKS 240
           EDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASY+S
Sbjct: 270 EDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQS 329

Query: 241 YSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDHEATGPRLSRELLDEKGPEVLQDSLDRCY 300
           YSSTFHSLEEQQVCMAVDIGRHRWDQVKKED EATGPRLSRELLDEKGPEVLQDSLDRCY
Sbjct: 330 YSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLDRCY 389

Query: 301 STPSGCLELTDSCQPYRSAFYVLEQQRVGLAVNMDEIEKYQEVEEDQDPSCPRLSRELLD 360
           STPSGCLELTDSCQPYRSAFYVLEQQR+GLAV+MDEIEKYQEVEEDQDPSCPRLSRELLD
Sbjct: 390 STPSGCLELTDSCQPYRSAFYVLEQQRIGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLD 449

Query: 361 EKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEE 420
           EKEPEVLQDSL RCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDR KKDQEEEE
Sbjct: 450 EKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEE 509

Query: 421 DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGF 480
           DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGF
Sbjct: 510 DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGF 569

Query: 481 SLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSL 540
           SLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSL
Sbjct: 570 SLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSL 629

Query: 541 DRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSG 600
           DRCYSTPSGCLELTDSCQPYRSAFY+LEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLS 
Sbjct: 630 DRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSR 689

Query: 601 ELLDEKEPEVLQESLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQ 660
           ELLDEKEPEVLQ+SLDRCYSTPSG LEL D  QPY SA Y LE+Q +GLA+D+D  +K Q
Sbjct: 690 ELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQ 749

Query: 661 EVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQ 720
           E EEDQ P CPRLSRELL+  EPEVLQDSL RCYSTPS  LE PD  QPY S+ Y+LEE+
Sbjct: 750 EEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEK 809

Query: 721 YLGLALDVDRIKKD-------------------QEEEEDQGPPCPRLSRELLEVVEPEVL 761
           ++G +LDV  I+K                    +E EEDQ PPCPRLSRELL+  EPEVL
Sbjct: 810 HVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVL 869

Query: 762 QDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSK 821
           QDSLDRCYSTPS  LE PD  QPY S+ Y+LEE+++G +LDV EIEK             
Sbjct: 870 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDEIEK------------- 916

Query: 822 KERRRGRKEGEEDQNPPCPRLNSMLMEVEEPEVLQDSLDICYSTPSMYFELPDSFQHYRS 881
                  +E EEDQ+P CPRL+  L++ +EPEVLQDSLD CYSTPS Y ELPD  Q Y S
Sbjct: 917 ------YQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSS 970

Query: 882 VFYSFEEEHISFALYVD 898
             YS EE+++  AL VD
Sbjct: 971 AVYSLEEQYLGLALDVD 987



 Score = 1156 bits (2991), Expect = 0.0
 Identities = 603/820 (73%), Positives = 648/820 (79%), Gaps = 55/820 (6%)

Query: 120  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 179
            RE+   +E EV +DSL+ C  T S      D  QP+     + EE  +   L        
Sbjct: 2585 RELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALD------- 2637

Query: 180  WEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTLSIPPEMLA 236
                   +   + D EEEE++GP  PR    L E  E EV Q+S D  YST S   E   
Sbjct: 2638 -------VDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPD 2690

Query: 237  SYKSYSSTFHSLEEQQVCMAVDIG-------------------RHRWDQVKKEDHEATGP 277
            S + Y S+F++LEE+ V  ++D+G                   R R  +  +ED     P
Sbjct: 2691 SCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCP 2750

Query: 278  RLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVNMDEI 337
            RLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAV+MDEI
Sbjct: 2751 RLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEI 2810

Query: 338  EKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYS 397
            EKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL RCYSTPSGYLELPDLGQPYSSAVYS
Sbjct: 2811 EKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYS 2870

Query: 398  LEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL 457
            LEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL
Sbjct: 2871 LEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL 2930

Query: 458  EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQN 517
            EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQN
Sbjct: 2931 EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQN 2990

Query: 518  PPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVD 577
            PPCPRLSRELLDEK PEVLQDSLDRCYSTPSG LEL D  QPY SA Y LE+Q +GLA+D
Sbjct: 2991 PPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALD 3050

Query: 578  MDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQESLDRCYSTPSGCLELTDSCQPYRS 637
            +D  +K QE EEDQ P CPRLS ELL+  EPEVLQ+SLDRCYSTPS CLE  DSCQPY S
Sbjct: 3051 VDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGS 3110

Query: 638  AFYILEQQRVGLAVDMDEIEK-------------------YQEVEEDQDPSCPRLSRELL 678
            +FY LE++ VG ++D+ EIEK                    +E EEDQ+P CPRLSRELL
Sbjct: 3111 SFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELL 3170

Query: 679  DEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEE 738
            DEKEPEVLQDSL RCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDR KKDQEEE
Sbjct: 3171 DEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEE 3230

Query: 739  EDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVG 798
            EDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVG
Sbjct: 3231 EDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVG 3290

Query: 799  FSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNSMLMEVEEPEVLQDS 858
            FSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRL+  L++ +EPEVLQDS
Sbjct: 3291 FSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDS 3350

Query: 859  LDICYSTPSMYFELPDSFQHYRSVFYSFEEEHISFALYVD 898
            LD CYSTPS Y ELPD  Q Y S  YS EE+++  AL VD
Sbjct: 3351 LDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD 3390



 Score = 1129 bits (2921), Expect = 0.0
 Identities = 597/843 (70%), Positives = 649/843 (76%), Gaps = 58/843 (6%)

Query: 100  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHR 156
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 666  DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 725

Query: 157  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 213
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 726  SAVYSLEEQYLGLALD--------------VDRTKKDQEEEEDQGPPCPRLSRELLEVVE 771

Query: 214  EEVPQESWDEGYSTLSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIG------------- 260
             EV Q+S D  YST S   E   S + Y S+F++LEE+ V  ++D+G             
Sbjct: 772  PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 831

Query: 261  ------RHRWDQVKKEDHEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 314
                  R R  +  +ED     PRLSRELLDEK PEVLQDSLDRCYSTPSG LEL D  Q
Sbjct: 832  RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQ 891

Query: 315  PYRSAFYVLEQQRVGLAVNMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRC 374
            PY SA Y LE+Q +GLA+++DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL RC
Sbjct: 892  PYSSAVYSLEEQYLGLALDVDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 951

Query: 375  YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 434
            YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELL
Sbjct: 952  YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 1011

Query: 435  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 494
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 1012 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 1071

Query: 495  KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 554
            KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEK PEVLQDSLDRCYSTPSG LEL 
Sbjct: 1072 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELP 1131

Query: 555  DSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQES 614
            D  QPY SA Y LE+Q +GLA+D+D  +K QE EEDQ P CPRLS ELL+  EPEVLQ+S
Sbjct: 1132 DLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDS 1191

Query: 615  LDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEK---------------- 658
            LDRCYSTPS CLE  DSCQPY S+FY LE++ VG ++D+ EIEK                
Sbjct: 1192 LDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKER 1251

Query: 659  ---YQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVY 715
                +E EEDQ+P CPRLSRELLDEKEPEVLQDSL RCYSTPSGYLELPDLGQPYSSAVY
Sbjct: 1252 RRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVY 1311

Query: 716  SLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSC 775
            SLEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSC
Sbjct: 1312 SLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSC 1371

Query: 776  LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQ 835
            LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQ
Sbjct: 1372 LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQ 1431

Query: 836  NPPCPRLNSMLMEVEEPEVLQDSLDICYSTPSMYFELPDSFQHYRSVFYSFEEEHISFAL 895
            NPPCPRL+  L++ +EPEVLQDSLD CYSTPS Y ELPD  Q Y S  YS EE+++  AL
Sbjct: 1432 NPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 1491

Query: 896  YVD 898
             VD
Sbjct: 1492 DVD 1494



 Score = 1058 bits (2737), Expect = 0.0
 Identities = 566/843 (67%), Positives = 624/843 (74%), Gaps = 77/843 (9%)

Query: 100  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHR 156
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 1661 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 1720

Query: 157  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 213
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 1721 SAVYSLEEQYLGLALD--------------VDRTKKDQEEEEDQGPPCPRLSRELLEVVE 1766

Query: 214  EEVPQESWDEGYSTLSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIG------------- 260
             EV Q+S D  YST S   E   S + Y S+F++LEE+ V  ++D+G             
Sbjct: 1767 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 1826

Query: 261  ------RHRWDQVKKEDHEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 314
                  R R  +  +ED     PRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 1827 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 1886

Query: 315  PYRSAFYVLEQQRVGLAVNMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRC 374
            PYRSAFYVLEQQRVGLAV+MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL RC
Sbjct: 1887 PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 1946

Query: 375  YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 434
            YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELL
Sbjct: 1947 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 2006

Query: 435  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 494
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 2007 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 2066

Query: 495  KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 554
            KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDR YSTPSGCLELT
Sbjct: 2067 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELT 2126

Query: 555  DSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQES 614
            DSCQPYRSAFY+LEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLS ELLDEKEPEVLQ+S
Sbjct: 2127 DSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDS 2186

Query: 615  LDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLS 674
            LDRCYSTPSG LEL D  QPY SA Y LE+Q +GLA+D+D  +K QE EEDQ P CPRLS
Sbjct: 2187 LDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLS 2246

Query: 675  RELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKD 734
            RELL+  EPEVLQDSL RCYSTPS  LE PD  QPY S+ Y+LEE+++G +LDV  I+K 
Sbjct: 2247 RELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKK 2306

Query: 735  -------------------QEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSC 775
                               +E EEDQ PPCPRLSRELL+   PEVLQDSLDRCYSTPS C
Sbjct: 2307 GKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGC 2366

Query: 776  LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQ 835
            LE  DSCQPY S+FY LE++ VG ++D+ EIEK                    +E EEDQ
Sbjct: 2367 LELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEK-------------------YQEVEEDQ 2407

Query: 836  NPPCPRLNSMLMEVEEPEVLQDSLDICYSTPSMYFELPDSFQHYRSVFYSFEEEHISFAL 895
            +P CPRL+  L++ +EPEVLQDSLD CYSTPS Y ELPD  Q Y S  YS EE+++  AL
Sbjct: 2408 DPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 2467

Query: 896  YVD 898
             VD
Sbjct: 2468 DVD 2470



 Score = 1055 bits (2729), Expect = 0.0
 Identities = 567/842 (67%), Positives = 625/842 (74%), Gaps = 77/842 (9%)

Query: 100  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHR 156
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 1905 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 1964

Query: 157  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 213
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 1965 SAVYSLEEQYLGLALD--------------VDRTKKDQEEEEDQGPPCPRLSRELLEVVE 2010

Query: 214  EEVPQESWDEGYSTLSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIG------------- 260
             EV Q+S D  YST S   E   S + Y S+F++LEE+ V  ++D+G             
Sbjct: 2011 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 2070

Query: 261  ------RHRWDQVKKEDHEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 314
                  R R  +  +ED     PRLSRELLDEKGPEVLQDSLDR YSTPSGCLELTDSCQ
Sbjct: 2071 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQ 2130

Query: 315  PYRSAFYVLEQQRVGLAVNMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRC 374
            PYRSAFYVLEQQRVGLAV+MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL RC
Sbjct: 2131 PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 2190

Query: 375  YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 434
            YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELL
Sbjct: 2191 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 2250

Query: 435  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 494
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 2251 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 2310

Query: 495  KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 554
            KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT
Sbjct: 2311 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 2370

Query: 555  DSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQES 614
            DSCQPYRSAFY+LEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLS ELLDEKEPEVLQ+S
Sbjct: 2371 DSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDS 2430

Query: 615  LDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLS 674
            LDRCYSTPSG LEL D  QPY SA Y LE+Q +GLA+D+D  +K QE EEDQ P CPRLS
Sbjct: 2431 LDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLS 2490

Query: 675  RELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKD 734
            RELL+  EPEVLQDSL RCYSTPS  LE PD  QPY S+ Y+LEE+++G +LDV  I+K 
Sbjct: 2491 RELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKK 2550

Query: 735  -------------------QEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSC 775
                               +E EEDQ PPCPRLSRELL+  EPEVLQDSLDRCYSTPS  
Sbjct: 2551 GKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGY 2610

Query: 776  LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQ 835
            LE PD  QPY S+ Y+LEE+++G +LDV               R+KK+     +E EEDQ
Sbjct: 2611 LELPDLGQPYSSAVYSLEEQYLGLALDVD--------------RTKKD-----QEEEEDQ 2651

Query: 836  NPPCPRLNSMLMEVEEPEVLQDSLDICYSTPSMYFELPDSFQHYRSVFYSFEEEHISFAL 895
             PPCPRL+  L+EV EPEVLQDSLD CYSTPS   E PDS Q Y S FY+ EE+H+ F+L
Sbjct: 2652 GPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSL 2711

Query: 896  YV 897
             V
Sbjct: 2712 DV 2713



 Score = 1054 bits (2725), Expect = 0.0
 Identities = 559/820 (68%), Positives = 614/820 (74%), Gaps = 74/820 (9%)

Query: 120  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 179
            RE+   +E EV +DSL+ C  T S      D  QP+     + EE  +   L        
Sbjct: 1440 RELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALD------- 1492

Query: 180  WEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTLSIPPEMLA 236
                   +   + D EEEE++GP  PR    L E  E EV Q+S D  YST S   E   
Sbjct: 1493 -------VDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPD 1545

Query: 237  SYKSYSSTFHSLEEQQVCMAVDIG-------------------RHRWDQVKKEDHEATGP 277
            S + Y S+F++LEE+ V  ++D+G                   R R  +  +ED     P
Sbjct: 1546 SCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCP 1605

Query: 278  RLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVNMDEI 337
            RLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAV+MDEI
Sbjct: 1606 RLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEI 1665

Query: 338  EKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYS 397
            EKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL RCYSTPSGYLELPDLGQPYSSAVYS
Sbjct: 1666 EKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYS 1725

Query: 398  LEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL 457
            LEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL
Sbjct: 1726 LEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL 1785

Query: 458  EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQN 517
            EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQN
Sbjct: 1786 EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQN 1845

Query: 518  PPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVD 577
            PPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFY+LEQQRVGLAVD
Sbjct: 1846 PPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVD 1905

Query: 578  MDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQESLDRCYSTPSGCLELTDSCQPYRS 637
            MDEIEKYQEVEEDQDPSCPRLS ELLDEKEPEVLQ+SLDRCYSTPSG LEL D  QPY S
Sbjct: 1906 MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSS 1965

Query: 638  AFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRCYSTP 697
            A Y LE+Q +GLA+D+D  +K QE EEDQ P CPRLSRELL+  EPEVLQDSL RCYSTP
Sbjct: 1966 AVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTP 2025

Query: 698  SGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKD-------------------QEEE 738
            S  LE PD  QPY S+ Y+LEE+++G +LDV  I+K                    +E E
Sbjct: 2026 SSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGE 2085

Query: 739  EDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVG 798
            EDQ PPCPRLSRELL+   PEVLQDSLDR YSTPS CLE  DSCQPY S+FY LE++ VG
Sbjct: 2086 EDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVG 2145

Query: 799  FSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNSMLMEVEEPEVLQDS 858
             ++D+ EIEK                    +E EEDQ+P CPRL+  L++ +EPEVLQDS
Sbjct: 2146 LAVDMDEIEK-------------------YQEVEEDQDPSCPRLSRELLDEKEPEVLQDS 2186

Query: 859  LDICYSTPSMYFELPDSFQHYRSVFYSFEEEHISFALYVD 898
            LD CYSTPS Y ELPD  Q Y S  YS EE+++  AL VD
Sbjct: 2187 LDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD 2226



 Score = 1028 bits (2658), Expect = 0.0
 Identities = 556/842 (66%), Positives = 617/842 (73%), Gaps = 77/842 (9%)

Query: 100  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHR 156
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 422  DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 481

Query: 157  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 213
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 482  SAVYSLEEQYLGLALD--------------VDRTKKDQEEEEDQGPPCPRLSRELLEVVE 527

Query: 214  EEVPQESWDEGYSTLSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIG------------- 260
             EV Q+S D  YST S   E   S + Y S+F++LEE+ V  ++D+G             
Sbjct: 528  PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 587

Query: 261  ------RHRWDQVKKEDHEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 314
                  R R  +  +ED     PRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 588  RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 647

Query: 315  PYRSAFYVLEQQRVGLAVNMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRC 374
            PYRSAFYVLEQQRVGLAV+MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL RC
Sbjct: 648  PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 707

Query: 375  YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 434
            YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELL
Sbjct: 708  YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 767

Query: 435  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 494
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 768  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 827

Query: 495  KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 554
            KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEK PEVLQDSLDRCYSTPSG LEL 
Sbjct: 828  KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELP 887

Query: 555  DSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQES 614
            D  QPY SA Y LE+Q +GLA+D+DEIEKYQEVEEDQDPSCPRLS ELLDEKEPEVLQ+S
Sbjct: 888  DLGQPYSSAVYSLEEQYLGLALDVDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDS 947

Query: 615  LDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLS 674
            LDRCYSTPSG LEL D  QPY SA Y LE+Q +GLA+D+D  +K QE EEDQ P CPRLS
Sbjct: 948  LDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLS 1007

Query: 675  RELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKD 734
            RELL+  EPEVLQDSL RCYSTPS  LE PD  QPY S+ Y+LEE+++G +LDV  I+K 
Sbjct: 1008 RELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKK 1067

Query: 735  -------------------QEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSC 775
                               +E EEDQ PPCPRLSRELL+  EPEVLQDSLDRCYSTPS  
Sbjct: 1068 GKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGY 1127

Query: 776  LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQ 835
            LE PD  QPY S+ Y+LEE+++G +LDV               R+KK+     +E EEDQ
Sbjct: 1128 LELPDLGQPYSSAVYSLEEQYLGLALDVD--------------RTKKD-----QEEEEDQ 1168

Query: 836  NPPCPRLNSMLMEVEEPEVLQDSLDICYSTPSMYFELPDSFQHYRSVFYSFEEEHISFAL 895
             PPCPRL+  L+EV EPEVLQDSLD CYSTPS   E PDS Q Y S FY+ EE+H+ F+L
Sbjct: 1169 GPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSL 1228

Query: 896  YV 897
             V
Sbjct: 1229 DV 1230



 Score = 1017 bits (2630), Expect = 0.0
 Identities = 551/842 (65%), Positives = 613/842 (72%), Gaps = 77/842 (9%)

Query: 100  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHR 156
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 2149 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 2208

Query: 157  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 213
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 2209 SAVYSLEEQYLGLALD--------------VDRTKKDQEEEEDQGPPCPRLSRELLEVVE 2254

Query: 214  EEVPQESWDEGYSTLSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIG------------- 260
             EV Q+S D  YST S   E   S + Y S+F++LEE+ V  ++D+G             
Sbjct: 2255 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 2314

Query: 261  ------RHRWDQVKKEDHEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 314
                  R R  +  +ED     PRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 2315 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 2374

Query: 315  PYRSAFYVLEQQRVGLAVNMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRC 374
            PYRSAFYVLEQQRVGLAV+MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL RC
Sbjct: 2375 PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 2434

Query: 375  YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 434
            YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELL
Sbjct: 2435 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 2494

Query: 435  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 494
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 2495 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 2554

Query: 495  KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 554
            KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEK PEVLQDSLDRCYSTPSG LEL 
Sbjct: 2555 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELP 2614

Query: 555  DSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQES 614
            D  QPY SA Y LE+Q +GLA+D+D  +K QE EEDQ P CPRLS ELL+  EPEVLQ+S
Sbjct: 2615 DLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDS 2674

Query: 615  LDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEK---------------- 658
            LDRCYSTPS CLE  DSCQPY S+FY LE++ VG ++D+ EIEK                
Sbjct: 2675 LDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKER 2734

Query: 659  ---YQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVY 715
                +E EEDQ+P CPRLSRELLDEK PEVLQDSL RCYSTPSG LEL D  QPY SA Y
Sbjct: 2735 RRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFY 2794

Query: 716  SLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSC 775
             LE+Q +GLA+D+D I+K QE EEDQ P CPRLSRELL+  EPEVLQDSLDRCYSTPS  
Sbjct: 2795 VLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGY 2854

Query: 776  LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQ 835
            LE PD  QPY S+ Y+LEE+++G +LDV               R+KK+     +E EEDQ
Sbjct: 2855 LELPDLGQPYSSAVYSLEEQYLGLALDVD--------------RTKKD-----QEEEEDQ 2895

Query: 836  NPPCPRLNSMLMEVEEPEVLQDSLDICYSTPSMYFELPDSFQHYRSVFYSFEEEHISFAL 895
             PPCPRL+  L+EV EPEVLQDSLD CYSTPS   E PDS Q Y S FY+ EE+H+ F+L
Sbjct: 2896 GPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSL 2955

Query: 896  YV 897
             V
Sbjct: 2956 DV 2957



 Score = 1003 bits (2592), Expect = 0.0
 Identities = 536/825 (64%), Positives = 606/825 (73%), Gaps = 65/825 (7%)

Query: 120  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 179
            RE+ +  E EV +DSL+ C  T S+     DS QP+  +    EE  V  +L       +
Sbjct: 1177 RELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKK 1236

Query: 180  WEDAVHIIPENESD-----DEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTLSIP 231
             +        ++ +      E EE++ P  PR    L + +E EV Q+S D  YST S  
Sbjct: 1237 GKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGY 1296

Query: 232  PEMLASYKSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDHEATGPRLSRELLDEKGPEV 291
             E+    + YSS  +SLEEQ + +A+D+ R + DQ ++ED     PRLSRELL+   PEV
Sbjct: 1297 LELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEV 1356

Query: 292  LQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVNMDEIEKY----------- 340
            LQDSLDRCYSTPS CLE  DSCQPY S+FY LE++ VG ++++ EIEK            
Sbjct: 1357 LQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRS 1416

Query: 341  --------QEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYS 392
                    +E EEDQ+P CPRLSRELLDEKEPEVLQDSL RCYSTPSGYLELPDLGQPYS
Sbjct: 1417 KKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 1476

Query: 393  SAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYST 452
            SAVYSLEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYST
Sbjct: 1477 SAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYST 1536

Query: 453  PSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEG 512
            PSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEG
Sbjct: 1537 PSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEG 1596

Query: 513  EEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRV 572
            EEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFY+LEQQRV
Sbjct: 1597 EEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRV 1656

Query: 573  GLAVDMDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQESLDRCYSTPSGCLELTDSC 632
            GLAVDMDEIEKYQEVEEDQDPSCPRLS ELLDEKEPEVLQ+SLDRCYSTPSG LEL D  
Sbjct: 1657 GLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLG 1716

Query: 633  QPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGR 692
            QPY SA Y LE+Q +GLA+D+D  +K QE EEDQ P CPRLSRELL+  EPEVLQDSL R
Sbjct: 1717 QPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDR 1776

Query: 693  CYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKD------------------ 734
            CYSTPS  LE PD  QPY S+ Y+LEE+++G +LDV  I+K                   
Sbjct: 1777 CYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRG 1836

Query: 735  -QEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALE 793
             +E EEDQ PPCPRLSRELL+   PEVLQDSLDRCYSTPS CLE  DSCQPY S+FY LE
Sbjct: 1837 RKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLE 1896

Query: 794  EKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNSMLMEVEEPE 853
            ++ VG ++D+ EIEK                    +E EEDQ+P CPRL+  L++ +EPE
Sbjct: 1897 QQRVGLAVDMDEIEK-------------------YQEVEEDQDPSCPRLSRELLDEKEPE 1937

Query: 854  VLQDSLDICYSTPSMYFELPDSFQHYRSVFYSFEEEHISFALYVD 898
            VLQDSLD CYSTPS Y ELPD  Q Y S  YS EE+++  AL VD
Sbjct: 1938 VLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD 1982



 Score = 1001 bits (2589), Expect = 0.0
 Identities = 537/819 (65%), Positives = 603/819 (73%), Gaps = 74/819 (9%)

Query: 120  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 179
            RE+   +  EV +DSL+ C  T S      DS QP+R      E+ +V   +        
Sbjct: 2341 RELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVD------- 2393

Query: 180  WEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTLSIPPEMLA 236
                   + E E   E EE++ P  PR    L + +E EV Q+S D  YST S   E+  
Sbjct: 2394 -------MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPD 2446

Query: 237  SYKSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDHEATGPRLSRELLDEKGPEVLQDSL 296
              + YSS  +SLEEQ + +A+D+ R + DQ ++ED     PRLSRELL+   PEVLQDSL
Sbjct: 2447 LGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSL 2506

Query: 297  DRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVNMDEIEKY---------------- 340
            DRCYSTPS CLE  DSCQPY S+FY LE++ VG ++++ EIEK                 
Sbjct: 2507 DRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERR 2566

Query: 341  ---QEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYS 397
               +E EEDQ+P CPRLSRELLDEKEPEVLQDSL RCYSTPSGYLELPDLGQPYSSAVYS
Sbjct: 2567 RGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYS 2626

Query: 398  LEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL 457
            LEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL
Sbjct: 2627 LEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL 2686

Query: 458  EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQN 517
            EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQN
Sbjct: 2687 EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQN 2746

Query: 518  PPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVD 577
            PPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFY+LEQQRVGLAVD
Sbjct: 2747 PPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVD 2806

Query: 578  MDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQESLDRCYSTPSGCLELTDSCQPYRS 637
            MDEIEKYQEVEEDQDPSCPRLS ELLDEKEPEVLQ+SLDRCYSTPSG LEL D  QPY S
Sbjct: 2807 MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSS 2866

Query: 638  AFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRCYSTP 697
            A Y LE+Q +GLA+D+D  +K QE EEDQ P CPRLSRELL+  EPEVLQDSL RCYSTP
Sbjct: 2867 AVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTP 2926

Query: 698  SGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKD-------------------QEEE 738
            S  LE PD  QPY S+ Y+LEE+++G +LDV  I+K                    +E E
Sbjct: 2927 SSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGE 2986

Query: 739  EDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVG 798
            EDQ PPCPRLSRELL+  EPEVLQDSLDRCYSTPS  LE PD  QPY S+ Y+LEE+++G
Sbjct: 2987 EDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLG 3046

Query: 799  FSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNSMLMEVEEPEVLQDS 858
             +LDV               R+KK+     +E EEDQ PPCPRL+  L+EV EPEVLQDS
Sbjct: 3047 LALDVD--------------RTKKD-----QEEEEDQGPPCPRLSRELLEVVEPEVLQDS 3087

Query: 859  LDICYSTPSMYFELPDSFQHYRSVFYSFEEEHISFALYV 897
            LD CYSTPS   E PDS Q Y S FY+ EE+H+ F+L V
Sbjct: 3088 LDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 3126



 Score =  996 bits (2574), Expect = 0.0
 Identities = 535/820 (65%), Positives = 602/820 (73%), Gaps = 74/820 (9%)

Query: 120  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 179
            RE+   +  EV +DSL+ C  T S      DS QP+R      E+ +V   +        
Sbjct: 1853 RELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVD------- 1905

Query: 180  WEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTLSIPPEMLA 236
                   + E E   E EE++ P  PR    L + +E EV Q+S D  YST S   E+  
Sbjct: 1906 -------MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPD 1958

Query: 237  SYKSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDHEATGPRLSRELLDEKGPEVLQDSL 296
              + YSS  +SLEEQ + +A+D+ R + DQ ++ED     PRLSRELL+   PEVLQDSL
Sbjct: 1959 LGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSL 2018

Query: 297  DRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVNMDEIEKY---------------- 340
            DRCYSTPS CLE  DSCQPY S+FY LE++ VG ++++ EIEK                 
Sbjct: 2019 DRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERR 2078

Query: 341  ---QEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYS 397
               +E EEDQ+P CPRLSRELLDEK PEVLQDSL R YSTPSG LEL D  QPY SA Y 
Sbjct: 2079 RGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYV 2138

Query: 398  LEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL 457
            LE+Q +GLA+D+D I+K QE EEDQ P CPRLSRELL+  EPEVLQDSLDRCYSTPS  L
Sbjct: 2139 LEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYL 2198

Query: 458  EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQN 517
            E PD  QPY S+ Y+LEE+++G +LDV               R+KK++     E EEDQ 
Sbjct: 2199 ELPDLGQPYSSAVYSLEEQYLGLALDVD--------------RTKKDQ-----EEEEDQG 2239

Query: 518  PPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVD 577
            PPCPRLSRELL+   PEVLQDSLDRCYSTPS CLE  DSCQPY S+FY LE++ VG ++D
Sbjct: 2240 PPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLD 2299

Query: 578  MDEIEKY-------------------QEVEEDQDPSCPRLSGELLDEKEPEVLQESLDRC 618
            + EIEK                    +E EEDQ+P CPRLS ELLDEK PEVLQ+SLDRC
Sbjct: 2300 VGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRC 2359

Query: 619  YSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELL 678
            YSTPSGCLELTDSCQPYRSAFY+LEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELL
Sbjct: 2360 YSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELL 2419

Query: 679  DEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEE 738
            DEKEPEVLQDSL RCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDR KKDQEEE
Sbjct: 2420 DEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEE 2479

Query: 739  EDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVG 798
            EDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVG
Sbjct: 2480 EDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVG 2539

Query: 799  FSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNSMLMEVEEPEVLQDS 858
            FSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRL+  L++ +EPEVLQDS
Sbjct: 2540 FSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDS 2599

Query: 859  LDICYSTPSMYFELPDSFQHYRSVFYSFEEEHISFALYVD 898
            LD CYSTPS Y ELPD  Q Y S  YS EE+++  AL VD
Sbjct: 2600 LDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD 2639



 Score =  984 bits (2543), Expect = 0.0
 Identities = 532/851 (62%), Positives = 603/851 (70%), Gaps = 93/851 (10%)

Query: 120  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 179
            RE+   +E EV +DSL+ C  T S      D  QP+     + EE  +   L        
Sbjct: 2998 RELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALD------- 3050

Query: 180  WEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTLSIPPEMLA 236
                   +   + D EEEE++GP  PR    L E  E EV Q+S D  YST S   E   
Sbjct: 3051 -------VDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPD 3103

Query: 237  SYKSYSSTFHSLEEQQVCMAVDIG-------------------RHRWDQVKKEDHEATGP 277
            S + Y S+F++LEE+ V  ++D+G                   R R  +  +ED     P
Sbjct: 3104 SCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCP 3163

Query: 278  RLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVNMDEI 337
            RLSRELLDEK PEVLQDSLDRCYSTPSG LEL D  QPY SA Y LE+Q +GLA+++D  
Sbjct: 3164 RLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRT 3223

Query: 338  EKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYS 397
            +K QE EEDQ P CPRLSRELL+  EPEVLQDSL RCYSTPS  LE PD  QPY S+ Y+
Sbjct: 3224 KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYA 3283

Query: 398  LEEQYLGLALDVDRIKKD-------------------QEEEEDQGPPCPRLSRELLEVVE 438
            LEE+++G +LDV  I+K                    +E EEDQ PPCPRLSRELL+  E
Sbjct: 3284 LEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKE 3343

Query: 439  PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 498
            PEVLQDSLDRCYSTPS  LE PD  QPY S+ Y+LEE+++G +LDV              
Sbjct: 3344 PEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD------------- 3390

Query: 499  RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 558
             R+KK++     E EEDQ PPCPRLSRELL+   PEVLQDSLDRCYSTPS CLE  DSCQ
Sbjct: 3391 -RTKKDQ-----EEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQ 3444

Query: 559  PYRSAFYILEQQRVGLAVDMDEIEKY-------------------QEVEEDQDPSCPRLS 599
            PY S+FY LE++ VG ++D+ EIEK                    +E EEDQ+P CPRLS
Sbjct: 3445 PYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLS 3504

Query: 600  GELLDEKEPEVLQESLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKY 659
             ELLDEK PEVLQ+SLDR YSTPSGCLELTDSCQPYRSAFY+LEQQRVGLAVDMDEIEKY
Sbjct: 3505 RELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKY 3564

Query: 660  QEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEE 719
            QEVEEDQDPSCPRLSRELLDEKEPEVLQDSL RCYSTPSGYLELPDLGQPYSSAVYSLEE
Sbjct: 3565 QEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEE 3624

Query: 720  QYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQP 779
            QYLGLALDVDR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQP
Sbjct: 3625 QYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQP 3684

Query: 780  DSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPC 839
            DSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPC
Sbjct: 3685 DSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPC 3744

Query: 840  PRLNSMLMEVEEPEVLQDSLDICYSTPSMYFELPDSFQHYRSVFYSFEEEHISFALYVDN 899
            PRL+  L++ + PEVLQDSLD CYSTPS   EL DS Q YRS FY  E++ +  A+ +D 
Sbjct: 3745 PRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDG 3804

Query: 900  RFFTLTVTSLH 910
             + ++ V  +H
Sbjct: 3805 EYLSMKVIRIH 3815



 Score =  944 bits (2439), Expect = 0.0
 Identities = 512/825 (62%), Positives = 588/825 (71%), Gaps = 65/825 (7%)

Query: 120  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 179
            RE+ +  E EV +DSL+ C  T S+     DS QP+  +    EE  V  +L       +
Sbjct: 2003 RELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKK 2062

Query: 180  WEDAVHIIPENESD-----DEEEEEKGPVSPRNLQESEEE---EVPQESWDEGYSTLSIP 231
             +        ++ +      E EE++ P  PR  +E  +E   EV Q+S D  YST S  
Sbjct: 2063 GKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGC 2122

Query: 232  PEMLASYKSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDHEATGPRLSRELLDEKGPEV 291
             E+  S + Y S F+ LE+Q+V +AVD+      Q  +ED + + PRLSRELLDEK PEV
Sbjct: 2123 LELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEV 2182

Query: 292  LQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVNMDEIEKYQEVEEDQDPSC 351
            LQDSLDRCYSTPSG LEL D  QPY SA Y LE+Q +GLA+++D  +K QE EEDQ P C
Sbjct: 2183 LQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPC 2242

Query: 352  PRLSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDR 411
            PRLSRELL+  EPEVLQDSL RCYSTPS  LE PD  QPY S+ Y+LEE+++G +LDV  
Sbjct: 2243 PRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGE 2302

Query: 412  IKKD-------------------QEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYST 452
            I+K                    +E EEDQ PPCPRLSRELL+   PEVLQDSLDRCYST
Sbjct: 2303 IEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYST 2362

Query: 453  PSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEG 512
            PS CLE  DSCQPY S+FY LE++ VG ++D+ EIEK                    +E 
Sbjct: 2363 PSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKY-------------------QEV 2403

Query: 513  EEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRV 572
            EEDQ+P CPRLSRELLDEK PEVLQDSLDRCYSTPSG LEL D  QPY SA Y LE+Q +
Sbjct: 2404 EEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYL 2463

Query: 573  GLAVDMDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQESLDRCYSTPSGCLELTDSC 632
            GLA+D+D  +K QE EEDQ P CPRLS ELL+  EPEVLQ+SLDRCYSTPS CLE  DSC
Sbjct: 2464 GLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSC 2523

Query: 633  QPYRSAFYILEQQRVGLAVDMDEIEKY-------------------QEVEEDQDPSCPRL 673
            QPY S+FY LE++ VG ++D+ EIEK                    +E EEDQ+P CPRL
Sbjct: 2524 QPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRL 2583

Query: 674  SRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKK 733
            SRELLDEKEPEVLQDSL RCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDR KK
Sbjct: 2584 SRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKK 2643

Query: 734  DQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALE 793
            DQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALE
Sbjct: 2644 DQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALE 2703

Query: 794  EKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNSMLMEVEEPE 853
            EKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRL+  L++ + PE
Sbjct: 2704 EKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPE 2763

Query: 854  VLQDSLDICYSTPSMYFELPDSFQHYRSVFYSFEEEHISFALYVD 898
            VLQDSLD CYSTPS   EL DS Q YRS FY  E++ +  A+ +D
Sbjct: 2764 VLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMD 2808


>gi|157266285 hypothetical protein LOC728936 [Homo sapiens]
          Length = 670

 Score = 1087 bits (2812), Expect = 0.0
 Identities = 540/579 (93%), Positives = 555/579 (95%), Gaps = 1/579 (0%)

Query: 1   MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQA 60
           MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQA
Sbjct: 70  MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQA 129

Query: 61  LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR 120
           LLTPDEPDKSQGQDLQEQLAEGCRL QHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR
Sbjct: 130 LLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR 189

Query: 121 EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEW 180
           EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPH+KTKITFEEDKVDSTLIGSSSHVEW
Sbjct: 190 EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTLIGSSSHVEW 249

Query: 181 EDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYKS 240
           EDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASY+S
Sbjct: 250 EDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQS 309

Query: 241 YSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDHEATGPRLSRELLDEKGPEVLQDSLDRCY 300
           YSSTFHSLEEQQVCMAVDIGRHRWDQVKKED EATGPRLSRELLDEK PEVLQDSLDRCY
Sbjct: 310 YSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCY 369

Query: 301 STPSGCLELTDSCQPYRSAFYVLEQQRVGLAVNMDEIEKYQEVEEDQDPSCPRLSRELLD 360
           STPSGCLELTDSCQPYRSAFYVLEQQRVGLA++MDEIEKYQEVEEDQDPSCPRLSRELLD
Sbjct: 370 STPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLD 429

Query: 361 EKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEE 420
           EKEPEVLQDSL RCYSTPS YLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEE
Sbjct: 430 EKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEE 489

Query: 421 DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGF 480
           DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGF
Sbjct: 490 DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGF 549

Query: 481 SLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSL 540
           SLDVGEIEKKGKGKKRRGRRSKK+RRRGRKEGE+D NPPCPRL+  L++ + PEVLQDSL
Sbjct: 550 SLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDD-NPPCPRLNGVLMEVEEPEVLQDSL 608

Query: 541 DRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMD 579
           DRCYST S   EL DS Q YRS FY  E++ +  A+ +D
Sbjct: 609 DRCYSTQSMYFELPDSFQHYRSVFYSFEEEHISFALYVD 647



 Score =  696 bits (1795), Expect = 0.0
 Identities = 386/602 (64%), Positives = 439/602 (72%), Gaps = 36/602 (5%)

Query: 335 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSA 394
           +E+ +Y+ +   Q+    +L  +L + ++     +   +   TP          +P  S 
Sbjct: 90  EELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPD---------EPDKSQ 140

Query: 395 VYSLEEQYL-GLALDVDRIKK-----DQEEEED---------QGPPCPRLSRELLEVVEP 439
              L+EQ   G  L    ++K     D +++ED         Q    PR   E+ +  E 
Sbjct: 141 GQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR---EMQKAEEK 197

Query: 440 EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGR 499
           EV +DSL+ C  T S+     DS QP+  +    EE  V  +L       + +       
Sbjct: 198 EVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIP 257

Query: 500 RSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQP 559
            ++ +      E EE++ P  PR  +E  +E   EV Q+S D  YST S   E+  S Q 
Sbjct: 258 ENESD-----DEEEEEKGPVSPRNLQESEEE---EVPQESWDEGYSTLSIPPEMLASYQS 309

Query: 560 YRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQESLDRCY 619
           Y S F+ LE+Q+V +AVD+      Q  +EDQ+ + PRLS ELLDEKEPEVLQ+SLDRCY
Sbjct: 310 YSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCY 369

Query: 620 STPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLD 679
           STPSGCLELTDSCQPYRSAFY+LEQQRVGLA+DMDEIEKYQEVEEDQDPSCPRLSRELLD
Sbjct: 370 STPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLD 429

Query: 680 EKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEE 739
           EKEPEVLQDSL RCYSTPS YLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEE
Sbjct: 430 EKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEE 489

Query: 740 DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGF 799
           DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGF
Sbjct: 490 DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGF 549

Query: 800 SLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNSMLMEVEEPEVLQDSL 859
           SLDVGEIEKKGKGKKRRGRRSKK+RRRGRKEGE+D NPPCPRLN +LMEVEEPEVLQDSL
Sbjct: 550 SLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDD-NPPCPRLNGVLMEVEEPEVLQDSL 608

Query: 860 DICYSTPSMYFELPDSFQHYRSVFYSFEEEHISFALYVDNRFFTLTVTSLHLVFQMGVIF 919
           D CYST SMYFELPDSFQHYRSVFYSFEEEHISFALYVDNRFFTLTVTSLHLVFQMGVIF
Sbjct: 609 DRCYSTQSMYFELPDSFQHYRSVFYSFEEEHISFALYVDNRFFTLTVTSLHLVFQMGVIF 668

Query: 920 PQ 921
           PQ
Sbjct: 669 PQ 670


>gi|29789405 hypothetical protein LOC284565 [Homo sapiens]
          Length = 670

 Score = 1084 bits (2803), Expect = 0.0
 Identities = 539/579 (93%), Positives = 553/579 (95%), Gaps = 1/579 (0%)

Query: 1   MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQA 60
           MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQA
Sbjct: 70  MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQA 129

Query: 61  LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR 120
           LLTPDEPDKSQGQDLQEQLAEGCRL QHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR
Sbjct: 130 LLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR 189

Query: 121 EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEW 180
           EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPH+KTKITFEEDKVDSTLIGSSSHVEW
Sbjct: 190 EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTLIGSSSHVEW 249

Query: 181 EDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYKS 240
           EDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASY+S
Sbjct: 250 EDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQS 309

Query: 241 YSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDHEATGPRLSRELLDEKGPEVLQDSLDRCY 300
           YSSTFHSLEEQQVCMAVDIGRHRWDQVKKED EATGPRLSRELLDEK PEVLQDSLDRCY
Sbjct: 310 YSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCY 369

Query: 301 STPSGCLELTDSCQPYRSAFYVLEQQRVGLAVNMDEIEKYQEVEEDQDPSCPRLSRELLD 360
           STPSGCLELTDSCQPYRSAFYVLEQQRVGLA++MDEIEKYQEVEEDQDPSCPRLSRELLD
Sbjct: 370 STPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLD 429

Query: 361 EKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEE 420
           EKEPEVLQDSL RCYSTPS YLELPDLGQPYSSAVYSLEEQYLGLAL VDRIKKDQEEEE
Sbjct: 430 EKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDRIKKDQEEEE 489

Query: 421 DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGF 480
           DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGF
Sbjct: 490 DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGF 549

Query: 481 SLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSL 540
           SLDVGEIEKKGKGKKRRGRRSKK+RRRGRKEGE+D NPPCPRL   L++ + PEVLQDSL
Sbjct: 550 SLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDD-NPPCPRLYGVLMEVEEPEVLQDSL 608

Query: 541 DRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMD 579
           DRCYSTPS   E  DS Q YRS FY  E++ +  A+ +D
Sbjct: 609 DRCYSTPSMYFEQPDSFQHYRSVFYSFEEEHISFALYVD 647



 Score =  690 bits (1781), Expect = 0.0
 Identities = 384/602 (63%), Positives = 437/602 (72%), Gaps = 36/602 (5%)

Query: 335 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSA 394
           +E+ +Y+ +   Q+    +L  +L + ++     +   +   TP          +P  S 
Sbjct: 90  EELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPD---------EPDKSQ 140

Query: 395 VYSLEEQYL-GLALDVDRIKK-----DQEEEED---------QGPPCPRLSRELLEVVEP 439
              L+EQ   G  L    ++K     D +++ED         Q    PR   E+ +  E 
Sbjct: 141 GQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR---EMQKAEEK 197

Query: 440 EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGR 499
           EV +DSL+ C  T S+     DS QP+  +    EE  V  +L       + +       
Sbjct: 198 EVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIP 257

Query: 500 RSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQP 559
            ++ +      E EE++ P  PR  +E  +E   EV Q+S D  YST S   E+  S Q 
Sbjct: 258 ENESD-----DEEEEEKGPVSPRNLQESEEE---EVPQESWDEGYSTLSIPPEMLASYQS 309

Query: 560 YRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQESLDRCY 619
           Y S F+ LE+Q+V +AVD+      Q  +EDQ+ + PRLS ELLDEKEPEVLQ+SLDRCY
Sbjct: 310 YSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCY 369

Query: 620 STPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLD 679
           STPSGCLELTDSCQPYRSAFY+LEQQRVGLA+DMDEIEKYQEVEEDQDPSCPRLSRELLD
Sbjct: 370 STPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLD 429

Query: 680 EKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEE 739
           EKEPEVLQDSL RCYSTPS YLELPDLGQPYSSAVYSLEEQYLGLAL VDRIKKDQEEEE
Sbjct: 430 EKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDRIKKDQEEEE 489

Query: 740 DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGF 799
           DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGF
Sbjct: 490 DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGF 549

Query: 800 SLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNSMLMEVEEPEVLQDSL 859
           SLDVGEIEKKGKGKKRRGRRSKK+RRRGRKEGE+D NPPCPRL  +LMEVEEPEVLQDSL
Sbjct: 550 SLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDD-NPPCPRLYGVLMEVEEPEVLQDSL 608

Query: 860 DICYSTPSMYFELPDSFQHYRSVFYSFEEEHISFALYVDNRFFTLTVTSLHLVFQMGVIF 919
           D CYSTPSMYFE PDSFQHYRSVFYSFEEEHISFALYVDNRFFTLTVTSLHLVFQMGVIF
Sbjct: 609 DRCYSTPSMYFEQPDSFQHYRSVFYSFEEEHISFALYVDNRFFTLTVTSLHLVFQMGVIF 668

Query: 920 PQ 921
           PQ
Sbjct: 669 PQ 670


>gi|83415174 hypothetical protein LOC400818 [Homo sapiens]
          Length = 942

 Score = 1081 bits (2796), Expect = 0.0
 Identities = 542/579 (93%), Positives = 553/579 (95%)

Query: 1   MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQA 60
           MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQA
Sbjct: 341 MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQA 400

Query: 61  LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR 120
           LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDD+EDVQVEVAEKVQKSSAPR
Sbjct: 401 LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQKSSAPR 460

Query: 121 EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEW 180
           EMQKAEEKEVPEDSLEECAIT SNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 
Sbjct: 461 EMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVER 520

Query: 181 EDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYKS 240
           EDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYST SIPPEMLASYKS
Sbjct: 521 EDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTPSIPPEMLASYKS 580

Query: 241 YSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDHEATGPRLSRELLDEKGPEVLQDSLDRCY 300
           YSSTFHSLEEQQVCMAVDIGRHRWDQVKKED EATGPRLSRELLDEKGPEVLQDSL RCY
Sbjct: 581 YSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLYRCY 640

Query: 301 STPSGCLELTDSCQPYRSAFYVLEQQRVGLAVNMDEIEKYQEVEEDQDPSCPRLSRELLD 360
           STPSGCLELTDSCQPYRSAFYVLEQQRVGLAV+MDEIEKYQEVEEDQDPSCPRLSRELLD
Sbjct: 641 STPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLD 700

Query: 361 EKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEE 420
           EKEPEVLQDSLGR YSTPSGY ELPDLGQPYSSAVYSLEEQYLGLALD+DRIKKDQEEEE
Sbjct: 701 EKEPEVLQDSLGRWYSTPSGYPELPDLGQPYSSAVYSLEEQYLGLALDLDRIKKDQEEEE 760

Query: 421 DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGF 480
           DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDS QPYGSSFYALEEKHVGF
Sbjct: 761 DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSWQPYGSSFYALEEKHVGF 820

Query: 481 SLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSL 540
           SLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRL+  L++ + PEVLQDSL
Sbjct: 821 SLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEPEVLQDSL 880

Query: 541 DRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMD 579
           D CYSTPS   EL DS Q YRS FY  E+Q +  A+ +D
Sbjct: 881 DGCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYVD 919



 Score =  985 bits (2547), Expect = 0.0
 Identities = 568/929 (61%), Positives = 644/929 (69%), Gaps = 64/929 (6%)

Query: 1   MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQA 60
           MLRNERQFKEEKLAEQLKQAEELRQYKVLVH+QERELTQL+EKLREGRDASRSLNEHLQA
Sbjct: 70  MLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLKEKLREGRDASRSLNEHLQA 129

Query: 61  LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR 120
           LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPEND D+DEDVQVE  EKV +S APR
Sbjct: 130 LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEDEKVLESPAPR 189

Query: 121 EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLI--GSSSHV 178
           E+QKAEE +V EDSLEECAITCSNSHGP DSNQPH+  KITFEED+V+STL+    SSH 
Sbjct: 190 EVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTLVVDRESSHD 249

Query: 179 EWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASY 238
           E +DA++I+P            GP S            P  S     + L I  ++    
Sbjct: 250 ECQDALNILPV----------PGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQL 299

Query: 239 KSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDHEATGPRLSRELLDEKGPEVLQDSLDR 298
                 F +L+E+  C    +     +Q  K  +E     +   L +E+  +  ++ L  
Sbjct: 300 AEKKQQFRNLKEK--CFLTQLAGFLANQQNKYKYEECKDLIKFMLRNER--QFKEEKL-- 353

Query: 299 CYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVNMDEIEKYQEVEEDQDPSCPRLSREL 358
                +  L+  +  + Y+   +  E++   L       EK +E   D   S     + L
Sbjct: 354 -----AEQLKQAEELRQYKVLVHAQERELTQLR------EKLRE-GRDASRSLNEHLQAL 401

Query: 359 LDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEE 418
           L   EP+  Q                 DL +  +        Q+L   L  +    D E+
Sbjct: 402 LTPDEPDKSQGQ---------------DLQEQLAEGCRLA--QHLVQKLSPENDNDDNED 444

Query: 419 ------EEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYA 472
                 E+ Q    PR   E+ +  E EV +DSL+ C  T S+     DS QP+  +   
Sbjct: 445 VQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKIT 501

Query: 473 LEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKG 532
            EE  V  +L +G         +R              E EE++ P  PR  +E  +E  
Sbjct: 502 FEEDKVDSTL-IGS----SSHVEREDAVHIIPENESDDEEEEEKGPVSPRNLQESEEE-- 554

Query: 533 PEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQD 592
            EV Q+S D  YSTPS   E+  S + Y S F+ LE+Q+V +AVD+      Q  +EDQ+
Sbjct: 555 -EVPQESWDEGYSTPSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQE 613

Query: 593 PSCPRLSGELLDEKEPEVLQESLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVD 652
            + PRLS ELLDEK PEVLQ+SL RCYSTPSGCLELTDSCQPYRSAFY+LEQQRVGLAVD
Sbjct: 614 ATGPRLSRELLDEKGPEVLQDSLYRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVD 673

Query: 653 MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSS 712
           MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGR YSTPSGY ELPDLGQPYSS
Sbjct: 674 MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRWYSTPSGYPELPDLGQPYSS 733

Query: 713 AVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTP 772
           AVYSLEEQYLGLALD+DRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTP
Sbjct: 734 AVYSLEEQYLGLALDLDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTP 793

Query: 773 SSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGE 832
           SSCLEQPDS QPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGE
Sbjct: 794 SSCLEQPDSWQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGE 853

Query: 833 EDQNPPCPRLNSMLMEVEEPEVLQDSLDICYSTPSMYFELPDSFQHYRSVFYSFEEEHIS 892
           EDQNPPCPRLN +LMEVEEPEVLQDSLD CYSTPSMYFELPDSFQHYRSVFYSFEE+HIS
Sbjct: 854 EDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEQHIS 913

Query: 893 FALYVDNRFFTLTVTSLHLVFQMGVIFPQ 921
           FALYVDNRFFTLTVTSLHLVFQM VIFPQ
Sbjct: 914 FALYVDNRFFTLTVTSLHLVFQMEVIFPQ 942


>gi|92110019 hypothetical protein LOC55672 [Homo sapiens]
          Length = 1214

 Score = 1078 bits (2787), Expect = 0.0
 Identities = 536/580 (92%), Positives = 550/580 (94%), Gaps = 1/580 (0%)

Query: 1    MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQA 60
            +LRNERQFKEEKLAEQLKQAEELRQYKVLVH+QERELTQLREKLREGRDASRSLN+HLQA
Sbjct: 612  VLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNQHLQA 671

Query: 61   LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR 120
            LLTPDEPDKSQGQDLQEQLAEGCRLAQ L QKLSPENDND DEDVQVEVAEKVQKSSAPR
Sbjct: 672  LLTPDEPDKSQGQDLQEQLAEGCRLAQQLFQKLSPENDNDHDEDVQVEVAEKVQKSSAPR 731

Query: 121  EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEW 180
            EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEW
Sbjct: 732  EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEW 791

Query: 181  EDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYKS 240
            EDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASY+S
Sbjct: 792  EDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQS 851

Query: 241  YSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDHEATGPRLSRELLDEKGPEVLQDSLDRCY 300
            YS TFHSLEEQQVCMAVDIG HRWDQVKKED EATGPRLSRELLDEKGPEVLQDSLDRCY
Sbjct: 852  YSGTFHSLEEQQVCMAVDIGGHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLDRCY 911

Query: 301  STPSGCLELTDSCQPYRSAFYVLEQQRVGLAVNMDEIEKYQEVEEDQDPSCPRLSRELLD 360
            STPSG LELTDSCQPYRSAFY+LEQQRVG A++MDEIEKYQEVEEDQDPSCPRLSRELLD
Sbjct: 912  STPSGYLELTDSCQPYRSAFYILEQQRVGWALDMDEIEKYQEVEEDQDPSCPRLSRELLD 971

Query: 361  EKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEE 420
            EKEPEVLQDSL RCYSTPSGYLELPDLGQPY SAVYSLEEQYLGLALDVDRIKKDQEEEE
Sbjct: 972  EKEPEVLQDSLDRCYSTPSGYLELPDLGQPYRSAVYSLEEQYLGLALDVDRIKKDQEEEE 1031

Query: 421  DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGF 480
            DQGPPCPRLSRELLE VEPEVLQDSLDRCYSTPSSCLEQPDSC PYGSSFYALEEKHVGF
Sbjct: 1032 DQGPPCPRLSRELLEAVEPEVLQDSLDRCYSTPSSCLEQPDSCLPYGSSFYALEEKHVGF 1091

Query: 481  SLDVGEIEKKGKGKKRRGRRS-KKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDS 539
            SLDVGEIEKKGKGKKRRGRRS KK RRRGRKEGEEDQNPPCPRLS  L++ + PEVLQDS
Sbjct: 1092 SLDVGEIEKKGKGKKRRGRRSTKKRRRRGRKEGEEDQNPPCPRLSGMLMEVEEPEVLQDS 1151

Query: 540  LDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMD 579
            LDRCYSTPS   EL DS Q YRS FY  E+Q +  A+D+D
Sbjct: 1152 LDRCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALDVD 1191



 Score =  972 bits (2513), Expect = 0.0
 Identities = 564/938 (60%), Positives = 638/938 (68%), Gaps = 81/938 (8%)

Query: 1    MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQA 60
            MLRNERQFKEEKLAEQLKQAEELRQYKVLVH+QERELTQLREKLREGRDASRSLN+HLQA
Sbjct: 341  MLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNQHLQA 400

Query: 61   LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR 120
            LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPEND D+DEDVQVE AEKV +SSAPR
Sbjct: 401  LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAEKVLESSAPR 460

Query: 121  EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLI--GSSSHV 178
            E+QKAEE +VPEDSLEECAITCSNSHGP DSNQPH+   ITFEEDKV+S L+    SSH 
Sbjct: 461  EVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNINITFEEDKVNSALVVDRESSHD 520

Query: 179  EWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASY 238
            E +DAV+I+P            GP S            P  S     + L +  ++    
Sbjct: 521  ECQDAVNILPV----------PGPTSSATNVSMVVSAGPLSSEKAEMNILEMNEKLRPQL 570

Query: 239  KSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDHEATGP------RLSRELLDEKGPEVL 292
                  F +L+E+  C    +     +Q  K  +E          R  R+  +EK  E L
Sbjct: 571  AEKKQQFRNLKEK--CFVTQLACFLANQQNKYKYEECKDLIKSVLRNERQFKEEKLAEQL 628

Query: 293  QDSLDR------CYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVNMDEIEKYQ--EVE 344
            + + +        +S      +L +  +  R A   L Q    L +  DE +K Q  +++
Sbjct: 629  KQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNQHLQAL-LTPDEPDKSQGQDLQ 687

Query: 345  EDQDPSCPRLSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLG 404
            E     C RL+++L  +  PE   D                                   
Sbjct: 688  EQLAEGC-RLAQQLFQKLSPENDNDH---------------------------------- 712

Query: 405  LALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQ 464
               D D   +  E+ +    P     RE+ +  E EV +DSL+ C  T S+     DS Q
Sbjct: 713  ---DEDVQVEVAEKVQKSSAP-----REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQ 764

Query: 465  PYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLS 524
            P+  +    EE  V  +L       + +        ++ +      E EE++ P  PR  
Sbjct: 765  PHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESD-----DEEEEEKGPVSPRNL 819

Query: 525  RELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKY 584
            +E  +E   EV Q+S D  YST S   E+  S Q Y   F+ LE+Q+V +AVD+      
Sbjct: 820  QESEEE---EVPQESWDEGYSTLSIPPEMLASYQSYSGTFHSLEEQQVCMAVDIGGHRWD 876

Query: 585  QEVEEDQDPSCPRLSGELLDEKEPEVLQESLDRCYSTPSGCLELTDSCQPYRSAFYILEQ 644
            Q  +EDQ+ + PRLS ELLDEK PEVLQ+SLDRCYSTPSG LELTDSCQPYRSAFYILEQ
Sbjct: 877  QVKKEDQEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGYLELTDSCQPYRSAFYILEQ 936

Query: 645  QRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRCYSTPSGYLELP 704
            QRVG A+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL RCYSTPSGYLELP
Sbjct: 937  QRVGWALDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELP 996

Query: 705  DLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDS 764
            DLGQPY SAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLE VEPEVLQDS
Sbjct: 997  DLGQPYRSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEAVEPEVLQDS 1056

Query: 765  LDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRS-KKE 823
            LDRCYSTPSSCLEQPDSC PYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRS KK 
Sbjct: 1057 LDRCYSTPSSCLEQPDSCLPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSTKKR 1116

Query: 824  RRRGRKEGEEDQNPPCPRLNSMLMEVEEPEVLQDSLDICYSTPSMYFELPDSFQHYRSVF 883
            RRRGRKEGEEDQNPPCPRL+ MLMEVEEPEVLQDSLD CYSTPSMYFELPDSFQHYRSVF
Sbjct: 1117 RRRGRKEGEEDQNPPCPRLSGMLMEVEEPEVLQDSLDRCYSTPSMYFELPDSFQHYRSVF 1176

Query: 884  YSFEEEHISFALYVDNRFFTLTVTSLHLVFQMGVIFPQ 921
            YSFEE+HISFAL VDNRF TL  TSLHLVFQMGVIFPQ
Sbjct: 1177 YSFEEQHISFALDVDNRFLTLMGTSLHLVFQMGVIFPQ 1214



 Score =  536 bits (1382), Expect = e-152
 Identities = 395/1003 (39%), Positives = 510/1003 (50%), Gaps = 156/1003 (15%)

Query: 1    MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQA 60
            MLRNERQFKEEKLAEQLKQAEELRQYKVLVH+QERELTQLREKLREGRDASRSLN+HLQA
Sbjct: 70   MLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNQHLQA 129

Query: 61   LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR 120
            LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPEND D+DEDVQVE AEKV +SSAPR
Sbjct: 130  LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAEKVLESSAPR 189

Query: 121  EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLI--GSSSHV 178
            E+QKAEE +VPEDSLEECAITCSNSHGP DSNQPH+   ITFEEDKV+STL+    SSH 
Sbjct: 190  EVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNINITFEEDKVNSTLVVDRESSHD 249

Query: 179  EWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASY 238
            E +DAV+I+P            GP S            P  S     + L +  ++    
Sbjct: 250  ECQDAVNILP----------VPGPTSSATNVSMVVSAGPLSSEKAEMNILEMNEKLRPQL 299

Query: 239  KSYSSTFHSLEEQQVCMAVDIGRHRWDQVKK------EDHEATGPRLSRELLDEKGPEVL 292
                  F +L+E+  C    +     +Q  K      ED   +  R  R+  +EK  E L
Sbjct: 300  AEKKQQFRNLKEK--CFVTQLAGFLANQQNKYKYEECEDLIKSMLRNERQFKEEKLAEQL 357

Query: 293  QDSLD------RCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVNMDEIEKYQ----- 341
            + + +        +S      +L +  +  R A   L Q    L +  DE +K Q     
Sbjct: 358  KQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNQHLQAL-LTPDEPDKSQGQDLQ 416

Query: 342  -------------------EVEEDQDPSC----------PRLSRELLDEKEPEVLQDSLG 372
                               E +ED+D                 RE+   +E +V +DSL 
Sbjct: 417  EQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAEKVLESSAPREVQKAEESKVPEDSLE 476

Query: 373  RCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEE------------ 420
             C  T S      D  QP+ +   + EE  +  AL VDR     E ++            
Sbjct: 477  ECAITCSNSHGPCDSNQPHKNINITFEEDKVNSALVVDRESSHDECQDAVNILPVPGPTS 536

Query: 421  ---------DQGPPCPRLSR----ELLEVVEPEV------LQDSLDRCYSTPSSCL---- 457
                       GP     +     E+ E + P++       ++  ++C+ T  +C     
Sbjct: 537  SATNVSMVVSAGPLSSEKAEMNILEMNEKLRPQLAEKKQQFRNLKEKCFVTQLACFLANQ 596

Query: 458  -------EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRK 510
                   E  D  +    +    +E+ +   L   E  ++ K       R   + R   +
Sbjct: 597  QNKYKYEECKDLIKSVLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLR 656

Query: 511  EGEEDQNPPCPRLSRELL-DEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQ 569
            EG +        L   L  DE      QD  +          +L + C+  +  F  L  
Sbjct: 657  EGRDASRSLNQHLQALLTPDEPDKSQGQDLQE----------QLAEGCRLAQQLFQKLSP 706

Query: 570  QRVGLAVDMDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQESLDRCYSTPSGCLELT 629
            +      D DE  + +  E+ Q  S PR   E+   +E EV ++SL+ C  T S      
Sbjct: 707  ENDN---DHDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPY 760

Query: 630  DSCQPYRSAFYILEQQRVGLAV--------------DMDEIEKYQEVEEDQDPSCPRLSR 675
            DS QP+R      E+ +V   +               + E E   E EE++ P  P   R
Sbjct: 761  DSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSP---R 817

Query: 676  ELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQ 735
             L + +E EV Q+S    YST S   E+    Q YS   +SLEEQ + +A+D+   + DQ
Sbjct: 818  NLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSGTFHSLEEQQVCMAVDIGGHRWDQ 877

Query: 736  EEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEK 795
             ++EDQ    PRLSRELL+   PEVLQDSLDRCYSTPS  LE  DSCQPY S+FY LE++
Sbjct: 878  VKKEDQEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGYLELTDSCQPYRSAFYILEQQ 937

Query: 796  HVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNSMLMEVEEPEVL 855
             VG++LD+ EIEK                    +E EEDQ+P CPRL+  L++ +EPEVL
Sbjct: 938  RVGWALDMDEIEK-------------------YQEVEEDQDPSCPRLSRELLDEKEPEVL 978

Query: 856  QDSLDICYSTPSMYFELPDSFQHYRSVFYSFEEEHISFALYVD 898
            QDSLD CYSTPS Y ELPD  Q YRS  YS EE+++  AL VD
Sbjct: 979  QDSLDRCYSTPSGYLELPDLGQPYRSAVYSLEEQYLGLALDVD 1021


>gi|156071420 hypothetical protein LOC728912 [Homo sapiens]
          Length = 790

 Score =  880 bits (2273), Expect = 0.0
 Identities = 449/514 (87%), Positives = 466/514 (90%), Gaps = 6/514 (1%)

Query: 1   MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQA 60
           MLRNERQFKEEKLAEQLKQAEELRQYKVLVH+QERELTQLREKLREGRDASRSLNEHLQA
Sbjct: 266 MLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQA 325

Query: 61  LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR 120
           LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSS+PR
Sbjct: 326 LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPR 385

Query: 121 EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEW 180
           EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEW
Sbjct: 386 EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEW 445

Query: 181 EDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYKS 240
           EDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPE LASY+S
Sbjct: 446 EDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPERLASYQS 505

Query: 241 YSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDHEATGPRLSRELLDEKGPEVLQDSLDRCY 300
           YSSTFHSLEEQQVCMAVDIGRHRWDQVKKED EATGPRLSRELLDEK PEVLQDSLDRCY
Sbjct: 506 YSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCY 565

Query: 301 STPSGCLELTDSCQPYRSAFYVLEQQRVGLAVNMDEIEKYQEVEEDQDPSCPRLSRELLD 360
           STPS  L LTDSCQPYRSAFYVLEQQR+GLAV+MDEIEKYQEVEEDQDPSCPRLSRELL 
Sbjct: 566 STPSVYLGLTDSCQPYRSAFYVLEQQRIGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLA 625

Query: 361 EKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEE 420
           EKEPEVLQDSL RCYSTPSGYLELPDLGQPY SAVYSLEEQYLGLALDVDRIKKDQEEEE
Sbjct: 626 EKEPEVLQDSLDRCYSTPSGYLELPDLGQPYRSAVYSLEEQYLGLALDVDRIKKDQEEEE 685

Query: 421 DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGF 480
           DQGPPCPRLSRELLEVVEPEVLQDSLD     P   L       P    F    +  + F
Sbjct: 686 DQGPPCPRLSRELLEVVEPEVLQDSLDVIQLLP-VVLNSLTPASPTEVPFMHWRKNMLAF 744

Query: 481 SLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEE 514
            L   +++++G     RGR+  +E +R ++EGEE
Sbjct: 745 LLTWEKLKRRG-----RGRKEGEEDQRRKEEGEE 773



 Score =  646 bits (1667), Expect = 0.0
 Identities = 412/829 (49%), Positives = 503/829 (60%), Gaps = 86/829 (10%)

Query: 21  EELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLA 80
           +E++QYKVLVH+QERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLA
Sbjct: 15  QEIQQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLA 74

Query: 81  EGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAI 140
           EGCRLAQHLVQKLSPEND D+DEDVQVE  EKV +SSAPRE+QKAEE +VPEDSLEECAI
Sbjct: 75  EGCRLAQHLVQKLSPENDEDEDEDVQVEEDEKVLESSAPREVQKAEESKVPEDSLEECAI 134

Query: 141 TCSNSHGPYDSNQPHRKTKITFEEDKVDSTLI--GSSSHVEWEDAVHIIPENESDDEEEE 198
           TCSNSHGP DS QPH+  KITFEEDKV+S+L+    SSH   +DA++I+P          
Sbjct: 135 TCSNSHGPCDSIQPHKNIKITFEEDKVNSSLVVDRESSHDGCQDALNILPV--------- 185

Query: 199 EKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYKSYSSTFHSLEE-----QQV 253
             GP S            P  S     + L I  ++          F SL+E     Q  
Sbjct: 186 -PGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLCPQLAEKKQQFRSLKEKCFVTQVA 244

Query: 254 C-MAVDIGRHRWDQVKKEDHEATGPRLSRELLDEKGPEVLQDSLDR------CYSTPSGC 306
           C +A    ++++++ K  D   +  R  R+  +EK  E L+ + +        +S     
Sbjct: 245 CFLAKQQNKYKYEECK--DLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQEREL 302

Query: 307 LELTDSCQPYRSAFYVLEQQRVGLAVNMDEIEKYQ--EVEEDQDPSCPRLSRELLDEKEP 364
            +L +  +  R A   L +    L +  DE +K Q  +++E     C RL++ L+ +  P
Sbjct: 303 TQLREKLREGRDASRSLNEHLQAL-LTPDEPDKSQGQDLQEQLAEGC-RLAQHLVQKLSP 360

Query: 365 EVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGP 424
           E   D                                      D D   +  E+ +    
Sbjct: 361 ENDNDD-------------------------------------DEDVQVEVAEKVQKSSS 383

Query: 425 PCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 484
           P     RE+ +  E EV +DSL+ C  T S+     DS QP+  +    EE  V  +L  
Sbjct: 384 P-----REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIG 438

Query: 485 GEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCY 544
                + +        ++ +      E EE++ P  PR  +E  +E   EV Q+S D  Y
Sbjct: 439 SSSHVEWEDAVHIIPENESD-----DEEEEEKGPVSPRNLQESEEE---EVPQESWDEGY 490

Query: 545 STPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSGELLD 604
           ST S   E   S Q Y S F+ LE+Q+V +AVD+      Q  +EDQ+ + PRLS ELLD
Sbjct: 491 STLSIPPERLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLD 550

Query: 605 EKEPEVLQESLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEE 664
           EKEPEVLQ+SLDRCYSTPS  L LTDSCQPYRSAFY+LEQQR+GLAVDMDEIEKYQEVEE
Sbjct: 551 EKEPEVLQDSLDRCYSTPSVYLGLTDSCQPYRSAFYVLEQQRIGLAVDMDEIEKYQEVEE 610

Query: 665 DQDPSCPRLSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGL 724
           DQDPSCPRLSRELL EKEPEVLQDSL RCYSTPSGYLELPDLGQPY SAVYSLEEQYLGL
Sbjct: 611 DQDPSCPRLSRELLAEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYRSAVYSLEEQYLGL 670

Query: 725 ALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQP 784
           ALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLD     P   L       P
Sbjct: 671 ALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDVIQLLP-VVLNSLTPASP 729

Query: 785 YGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEE 833
               F    +  + F L   +++++G     RGR+  +E +R ++EGEE
Sbjct: 730 TEVPFMHWRKNMLAFLLTWEKLKRRG-----RGRKEGEEDQRRKEEGEE 773



 Score =  292 bits (747), Expect = 1e-78
 Identities = 184/384 (47%), Positives = 225/384 (58%), Gaps = 46/384 (11%)

Query: 525 RELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVD------- 577
           RE+   +  EV +DSL+ C  T S      DS QP+R      E+ +V   +        
Sbjct: 385 REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 444

Query: 578 -------MDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQESLDRCYSTPSGCLELTD 630
                  + E E   E EE++ P  PR    L + +E EV QES D  YST S   E   
Sbjct: 445 WEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTLSIPPERLA 501

Query: 631 SCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL 690
           S Q Y S F+ LE+Q+V +AVD+      Q  +EDQ+ + PRLSRELLDEKEPEVLQDSL
Sbjct: 502 SYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSL 561

Query: 691 GRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSR 750
            RCYSTPS YL L D  QPY SA Y LE+Q +GLA+D+D I+K QE EEDQ P CPRLSR
Sbjct: 562 DRCYSTPSVYLGLTDSCQPYRSAFYVLEQQRIGLAVDMDEIEKYQEVEEDQDPSCPRLSR 621

Query: 751 ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKG 810
           ELL   EPEVLQDSLDRCYSTPS  LE PD  QPY S+ Y+LEE+++G +LDV  I+K  
Sbjct: 622 ELLAEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYRSAVYSLEEQYLGLALDVDRIKKD- 680

Query: 811 KGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNSMLMEVEEPEVLQDSLDICY------- 863
                             +E EEDQ PPCPRL+  L+EV EPEVLQDSLD+         
Sbjct: 681 ------------------QEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDVIQLLPVVLN 722

Query: 864 -STPSMYFELPDSFQHYRSVFYSF 886
             TP+   E+P  F H+R    +F
Sbjct: 723 SLTPASPTEVP--FMHWRKNMLAF 744



 Score =  232 bits (592), Expect = 1e-60
 Identities = 201/620 (32%), Positives = 285/620 (45%), Gaps = 94/620 (15%)

Query: 335 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSA 394
           DE E  Q VEED+        RE+   +E +V +DSL  C  T S      D  QP+ + 
Sbjct: 94  DEDEDVQ-VEEDEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSIQPHKNI 152

Query: 395 VYSLEEQYLGLALDVDRIKKDQEEEE---------------------DQGP-PCPRLSRE 432
             + EE  +  +L VDR       ++                       GP    +    
Sbjct: 153 KITFEEDKVNSSLVVDRESSHDGCQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMN 212

Query: 433 LLEVVE---PEVLQDSL------DRCYSTPSSCL-------EQPDSCQPYGSSFYALE-- 474
           +LE+ E   P++ +         ++C+ T  +C         + + C+    S    E  
Sbjct: 213 ILEINEKLCPQLAEKKQQFRSLKEKCFVTQVACFLAKQQNKYKYEECKDLIKSMLRNERQ 272

Query: 475 --EKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKG 532
             E+ +   L   E  ++ K       R   + R   +EG +        L   L  ++ 
Sbjct: 273 FKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPDEP 332

Query: 533 PEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQD 592
            +     L           +L + C   R A +++++       D DE  + +  E+ Q 
Sbjct: 333 DKSQGQDLQE---------QLAEGC---RLAQHLVQKLSPENDNDDDEDVQVEVAEKVQK 380

Query: 593 PSCPRLSGELLDEKEPEVLQESLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVD 652
            S PR   E+   +E EV ++SL+ C  T S      DS QP+R      E+ +V   + 
Sbjct: 381 SSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLI 437

Query: 653 --------------MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRCYSTPS 698
                         + E E   E EE++ P  PR    L + +E EV Q+S    YST S
Sbjct: 438 GSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTLS 494

Query: 699 GYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEP 758
              E     Q YSS  +SLEEQ + +A+D+ R + DQ ++EDQ    PRLSRELL+  EP
Sbjct: 495 IPPERLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEP 554

Query: 759 EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGR 818
           EVLQDSLDRCYSTPS  L   DSCQPY S+FY LE++ +G ++D+ EIEK          
Sbjct: 555 EVLQDSLDRCYSTPSVYLGLTDSCQPYRSAFYVLEQQRIGLAVDMDEIEKY--------- 605

Query: 819 RSKKERRRGRKEGEEDQNPPCPRLNSMLMEVEEPEVLQDSLDICYSTPSMYFELPDSFQH 878
                     +E EEDQ+P CPRL+  L+  +EPEVLQDSLD CYSTPS Y ELPD  Q 
Sbjct: 606 ----------QEVEEDQDPSCPRLSRELLAEKEPEVLQDSLDRCYSTPSGYLELPDLGQP 655

Query: 879 YRSVFYSFEEEHISFALYVD 898
           YRS  YS EE+++  AL VD
Sbjct: 656 YRSAVYSLEEQYLGLALDVD 675


>gi|119709825 neuroblastoma breakpoint family, member 11-like [Homo
           sapiens]
          Length = 790

 Score =  880 bits (2273), Expect = 0.0
 Identities = 449/514 (87%), Positives = 466/514 (90%), Gaps = 6/514 (1%)

Query: 1   MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQA 60
           MLRNERQFKEEKLAEQLKQAEELRQYKVLVH+QERELTQLREKLREGRDASRSLNEHLQA
Sbjct: 266 MLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQA 325

Query: 61  LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR 120
           LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSS+PR
Sbjct: 326 LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPR 385

Query: 121 EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEW 180
           EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEW
Sbjct: 386 EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEW 445

Query: 181 EDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYKS 240
           EDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPE LASY+S
Sbjct: 446 EDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPERLASYQS 505

Query: 241 YSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDHEATGPRLSRELLDEKGPEVLQDSLDRCY 300
           YSSTFHSLEEQQVCMAVDIGRHRWDQVKKED EATGPRLSRELLDEK PEVLQDSLDRCY
Sbjct: 506 YSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCY 565

Query: 301 STPSGCLELTDSCQPYRSAFYVLEQQRVGLAVNMDEIEKYQEVEEDQDPSCPRLSRELLD 360
           STPS  L LTDSCQPYRSAFYVLEQQR+GLAV+MDEIEKYQEVEEDQDPSCPRLSRELL 
Sbjct: 566 STPSVYLGLTDSCQPYRSAFYVLEQQRIGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLA 625

Query: 361 EKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEE 420
           EKEPEVLQDSL RCYSTPSGYLELPDLGQPY SAVYSLEEQYLGLALDVDRIKKDQEEEE
Sbjct: 626 EKEPEVLQDSLDRCYSTPSGYLELPDLGQPYRSAVYSLEEQYLGLALDVDRIKKDQEEEE 685

Query: 421 DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGF 480
           DQGPPCPRLSRELLEVVEPEVLQDSLD     P   L       P    F    +  + F
Sbjct: 686 DQGPPCPRLSRELLEVVEPEVLQDSLDVIQLLP-VVLNSLTPASPTEVPFMHWRKNMLAF 744

Query: 481 SLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEE 514
            L   +++++G     RGR+  +E +R ++EGEE
Sbjct: 745 LLTWEKLKRRG-----RGRKEGEEDQRRKEEGEE 773



 Score =  647 bits (1670), Expect = 0.0
 Identities = 413/829 (49%), Positives = 503/829 (60%), Gaps = 86/829 (10%)

Query: 21  EELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLA 80
           EE++QYKVLVH+QERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLA
Sbjct: 15  EEIQQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLA 74

Query: 81  EGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAI 140
           EGCRLAQHLVQKLSPEND D+DEDVQVE  EKV +SSAPRE+QKAEE +VPEDSLEECAI
Sbjct: 75  EGCRLAQHLVQKLSPENDEDEDEDVQVEEDEKVLESSAPREVQKAEESKVPEDSLEECAI 134

Query: 141 TCSNSHGPYDSNQPHRKTKITFEEDKVDSTLI--GSSSHVEWEDAVHIIPENESDDEEEE 198
           TCSNSHGP DS QPH+  KITFEEDKV+S+L+    SSH   +DA++I+P          
Sbjct: 135 TCSNSHGPCDSIQPHKNIKITFEEDKVNSSLVVDRESSHDGCQDALNILPV--------- 185

Query: 199 EKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYKSYSSTFHSLEE-----QQV 253
             GP S            P  S     + L I  ++          F SL+E     Q  
Sbjct: 186 -PGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLCPQLAEKKQQFRSLKEKCFVTQVA 244

Query: 254 C-MAVDIGRHRWDQVKKEDHEATGPRLSRELLDEKGPEVLQDSLDR------CYSTPSGC 306
           C +A    ++++++ K  D   +  R  R+  +EK  E L+ + +        +S     
Sbjct: 245 CFLAKQQNKYKYEECK--DLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQEREL 302

Query: 307 LELTDSCQPYRSAFYVLEQQRVGLAVNMDEIEKYQ--EVEEDQDPSCPRLSRELLDEKEP 364
            +L +  +  R A   L +    L +  DE +K Q  +++E     C RL++ L+ +  P
Sbjct: 303 TQLREKLREGRDASRSLNEHLQAL-LTPDEPDKSQGQDLQEQLAEGC-RLAQHLVQKLSP 360

Query: 365 EVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGP 424
           E   D                                      D D   +  E+ +    
Sbjct: 361 ENDNDD-------------------------------------DEDVQVEVAEKVQKSSS 383

Query: 425 PCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 484
           P     RE+ +  E EV +DSL+ C  T S+     DS QP+  +    EE  V  +L  
Sbjct: 384 P-----REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIG 438

Query: 485 GEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCY 544
                + +        ++ +      E EE++ P  PR  +E  +E   EV Q+S D  Y
Sbjct: 439 SSSHVEWEDAVHIIPENESD-----DEEEEEKGPVSPRNLQESEEE---EVPQESWDEGY 490

Query: 545 STPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSGELLD 604
           ST S   E   S Q Y S F+ LE+Q+V +AVD+      Q  +EDQ+ + PRLS ELLD
Sbjct: 491 STLSIPPERLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLD 550

Query: 605 EKEPEVLQESLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEE 664
           EKEPEVLQ+SLDRCYSTPS  L LTDSCQPYRSAFY+LEQQR+GLAVDMDEIEKYQEVEE
Sbjct: 551 EKEPEVLQDSLDRCYSTPSVYLGLTDSCQPYRSAFYVLEQQRIGLAVDMDEIEKYQEVEE 610

Query: 665 DQDPSCPRLSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGL 724
           DQDPSCPRLSRELL EKEPEVLQDSL RCYSTPSGYLELPDLGQPY SAVYSLEEQYLGL
Sbjct: 611 DQDPSCPRLSRELLAEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYRSAVYSLEEQYLGL 670

Query: 725 ALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQP 784
           ALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLD     P   L       P
Sbjct: 671 ALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDVIQLLP-VVLNSLTPASP 729

Query: 785 YGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEE 833
               F    +  + F L   +++++G     RGR+  +E +R ++EGEE
Sbjct: 730 TEVPFMHWRKNMLAFLLTWEKLKRRG-----RGRKEGEEDQRRKEEGEE 773



 Score =  292 bits (747), Expect = 1e-78
 Identities = 184/384 (47%), Positives = 225/384 (58%), Gaps = 46/384 (11%)

Query: 525 RELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVD------- 577
           RE+   +  EV +DSL+ C  T S      DS QP+R      E+ +V   +        
Sbjct: 385 REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 444

Query: 578 -------MDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQESLDRCYSTPSGCLELTD 630
                  + E E   E EE++ P  PR    L + +E EV QES D  YST S   E   
Sbjct: 445 WEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTLSIPPERLA 501

Query: 631 SCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL 690
           S Q Y S F+ LE+Q+V +AVD+      Q  +EDQ+ + PRLSRELLDEKEPEVLQDSL
Sbjct: 502 SYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSL 561

Query: 691 GRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSR 750
            RCYSTPS YL L D  QPY SA Y LE+Q +GLA+D+D I+K QE EEDQ P CPRLSR
Sbjct: 562 DRCYSTPSVYLGLTDSCQPYRSAFYVLEQQRIGLAVDMDEIEKYQEVEEDQDPSCPRLSR 621

Query: 751 ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKG 810
           ELL   EPEVLQDSLDRCYSTPS  LE PD  QPY S+ Y+LEE+++G +LDV  I+K  
Sbjct: 622 ELLAEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYRSAVYSLEEQYLGLALDVDRIKKD- 680

Query: 811 KGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNSMLMEVEEPEVLQDSLDICY------- 863
                             +E EEDQ PPCPRL+  L+EV EPEVLQDSLD+         
Sbjct: 681 ------------------QEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDVIQLLPVVLN 722

Query: 864 -STPSMYFELPDSFQHYRSVFYSF 886
             TP+   E+P  F H+R    +F
Sbjct: 723 SLTPASPTEVP--FMHWRKNMLAF 744



 Score =  232 bits (592), Expect = 1e-60
 Identities = 201/620 (32%), Positives = 285/620 (45%), Gaps = 94/620 (15%)

Query: 335 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSA 394
           DE E  Q VEED+        RE+   +E +V +DSL  C  T S      D  QP+ + 
Sbjct: 94  DEDEDVQ-VEEDEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSIQPHKNI 152

Query: 395 VYSLEEQYLGLALDVDRIKKDQEEEE---------------------DQGP-PCPRLSRE 432
             + EE  +  +L VDR       ++                       GP    +    
Sbjct: 153 KITFEEDKVNSSLVVDRESSHDGCQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMN 212

Query: 433 LLEVVE---PEVLQDSL------DRCYSTPSSCL-------EQPDSCQPYGSSFYALE-- 474
           +LE+ E   P++ +         ++C+ T  +C         + + C+    S    E  
Sbjct: 213 ILEINEKLCPQLAEKKQQFRSLKEKCFVTQVACFLAKQQNKYKYEECKDLIKSMLRNERQ 272

Query: 475 --EKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKG 532
             E+ +   L   E  ++ K       R   + R   +EG +        L   L  ++ 
Sbjct: 273 FKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPDEP 332

Query: 533 PEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQD 592
            +     L           +L + C   R A +++++       D DE  + +  E+ Q 
Sbjct: 333 DKSQGQDLQE---------QLAEGC---RLAQHLVQKLSPENDNDDDEDVQVEVAEKVQK 380

Query: 593 PSCPRLSGELLDEKEPEVLQESLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVD 652
            S PR   E+   +E EV ++SL+ C  T S      DS QP+R      E+ +V   + 
Sbjct: 381 SSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLI 437

Query: 653 --------------MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRCYSTPS 698
                         + E E   E EE++ P  PR    L + +E EV Q+S    YST S
Sbjct: 438 GSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTLS 494

Query: 699 GYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEP 758
              E     Q YSS  +SLEEQ + +A+D+ R + DQ ++EDQ    PRLSRELL+  EP
Sbjct: 495 IPPERLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEP 554

Query: 759 EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGR 818
           EVLQDSLDRCYSTPS  L   DSCQPY S+FY LE++ +G ++D+ EIEK          
Sbjct: 555 EVLQDSLDRCYSTPSVYLGLTDSCQPYRSAFYVLEQQRIGLAVDMDEIEKY--------- 605

Query: 819 RSKKERRRGRKEGEEDQNPPCPRLNSMLMEVEEPEVLQDSLDICYSTPSMYFELPDSFQH 878
                     +E EEDQ+P CPRL+  L+  +EPEVLQDSLD CYSTPS Y ELPD  Q 
Sbjct: 606 ----------QEVEEDQDPSCPRLSRELLAEKEPEVLQDSLDRCYSTPSGYLELPDLGQP 655

Query: 879 YRSVFYSFEEEHISFALYVD 898
           YRS  YS EE+++  AL VD
Sbjct: 656 YRSAVYSLEEQYLGLALDVD 675


>gi|14149997 neuroblastoma breakpoint family, member 3 [Homo
           sapiens]
          Length = 633

 Score =  703 bits (1815), Expect = 0.0
 Identities = 361/484 (74%), Positives = 405/484 (83%)

Query: 1   MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQA 60
           MLR+ER   EEKLAE+L QAEELRQYKVLVH+QERELTQLREKL+EGRDASRSLN+HLQA
Sbjct: 126 MLRDERLLTEEKLAEELGQAEELRQYKVLVHSQERELTQLREKLQEGRDASRSLNQHLQA 185

Query: 61  LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR 120
           LLTPDEPD SQG+DL+EQLAEGCRLAQHLVQKLSPEND+D+DEDV+VE AEKVQ+  APR
Sbjct: 186 LLTPDEPDNSQGRDLREQLAEGCRLAQHLVQKLSPENDDDEDEDVKVEEAEKVQELYAPR 245

Query: 121 EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEW 180
           E+QKAEEKEVPEDSLEECAITCSNSH P +SNQP+  T+ITFEED+VDSTLI SSSH EW
Sbjct: 246 EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYGNTRITFEEDQVDSTLIDSSSHDEW 305

Query: 181 EDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYKS 240
            DAV IIPENESD E+EEEKGPVSPRNLQESEEEE PQESWDEG  TLSIPP+M ASY+S
Sbjct: 306 LDAVCIIPENESDHEQEEEKGPVSPRNLQESEEEEAPQESWDEGDWTLSIPPDMSASYQS 365

Query: 241 YSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDHEATGPRLSRELLDEKGPEVLQDSLDRCY 300
             STFHS+EEQQV +A+DIGRH  DQVKKED EAT PRLSRELLDEK PEVLQDSLDR Y
Sbjct: 366 DRSTFHSVEEQQVGLALDIGRHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFY 425

Query: 301 STPSGCLELTDSCQPYRSAFYVLEQQRVGLAVNMDEIEKYQEVEEDQDPSCPRLSRELLD 360
           STP   LEL D CQPYRS FY L++Q +GLA+++D ++K QE EEDQ P CPRLSREL +
Sbjct: 426 STPFEYLELPDLCQPYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPE 485

Query: 361 EKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEE 420
             EPE LQDSL R YSTP  Y ELPD  QPY S  YSLEE+++G +LDVD I+K QE EE
Sbjct: 486 VVEPEDLQDSLDRWYSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEKYQEGEE 545

Query: 421 DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGF 480
           DQ PPCPRL+  L+E  EPEVLQDSLDRCYST S+  +   S Q Y S+FY+ EE+ V  
Sbjct: 546 DQKPPCPRLNEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSL 605

Query: 481 SLDV 484
           +LDV
Sbjct: 606 ALDV 609



 Score =  408 bits (1048), Expect = e-113
 Identities = 239/425 (56%), Positives = 278/425 (65%), Gaps = 39/425 (9%)

Query: 510 KEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQ 569
           +E E+ Q    PR   E+   +  EV +DSL+ C  T S      +S QPY +     E+
Sbjct: 233 EEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYGNTRITFEE 289

Query: 570 QRV-GLAVD-------------MDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQESL 615
            +V    +D             + E E   E EE++ P  PR    L + +E E  QES 
Sbjct: 290 DQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPR---NLQESEEEEAPQESW 346

Query: 616 DRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSR 675
           D    T S   +++ S Q  RS F+ +E+Q+VGLA+D+      Q  +EDQ+ + PRLSR
Sbjct: 347 DEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIGRHWCDQVKKEDQEATSPRLSR 406

Query: 676 ELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQ 735
           ELLDEKEPEVLQDSL R YSTP  YLELPDL QPY S  YSL+EQ+LGLALD+DR+KKDQ
Sbjct: 407 ELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQPYRSDFYSLQEQHLGLALDLDRMKKDQ 466

Query: 736 EEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEK 795
           EEEEDQGPPCPRLSREL EVVEPE LQDSLDR YSTP S  E PDSCQPYGS FY+LEE+
Sbjct: 467 EEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRWYSTPFSYPELPDSCQPYGSCFYSLEEE 526

Query: 796 HVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNSMLMEVEEPEVL 855
           HVGFSLDV EIEK                    +EGEEDQ PPCPRLN +LME EEPEVL
Sbjct: 527 HVGFSLDVDEIEK-------------------YQEGEEDQKPPCPRLNEVLMEAEEPEVL 567

Query: 856 QDSLDICYSTPSMYFELPDSFQHYRSVFYSFEEEHISFALYVDNRFFTLTVTSLHLVFQM 915
           QDSLD CYST S YF+L  SFQ YRS FYSFEE+ +S AL VDNRFFTLTV   HL FQM
Sbjct: 568 QDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDVDNRFFTLTVIRHHLAFQM 627

Query: 916 GVIFP 920
           GVIFP
Sbjct: 628 GVIFP 632



 Score =  365 bits (937), Expect = e-100
 Identities = 216/410 (52%), Positives = 265/410 (64%), Gaps = 37/410 (9%)

Query: 188 PENESDDEEE---EEKGPV----SPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYKS 240
           PEN+ D++E+   EE   V    +PR +Q++EE+EVP++S +E   T S       S + 
Sbjct: 220 PENDDDEDEDVKVEEAEKVQELYAPREVQKAEEKEVPEDSLEECAITCSNSHHPCESNQP 279

Query: 241 YSSTFHSLEEQQV-CMAVDIGRH-RW---------DQVKKEDHEATGPRLSRELLDEKGP 289
           Y +T  + EE QV    +D   H  W         ++   E  E  GP   R L + +  
Sbjct: 280 YGNTRITFEEDQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPRNLQESEEE 339

Query: 290 EVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVNMDEIEKYQEVEEDQDP 349
           E  Q+S D    T S   +++ S Q  RS F+ +E+Q+VGLA+++      Q  +EDQ+ 
Sbjct: 340 EAPQESWDEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIGRHWCDQVKKEDQEA 399

Query: 350 SCPRLSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDV 409
           + PRLSRELLDEKEPEVLQDSL R YSTP  YLELPDL QPY S  YSL+EQ+LGLALD+
Sbjct: 400 TSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQPYRSDFYSLQEQHLGLALDL 459

Query: 410 DRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSS 469
           DR+KKDQEEEEDQGPPCPRLSREL EVVEPE LQDSLDR YSTP S  E PDSCQPYGS 
Sbjct: 460 DRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRWYSTPFSYPELPDSCQPYGSC 519

Query: 470 FYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLD 529
           FY+LEE+HVGFSLDV EIEK                    +EGEEDQ PPCPRL+  L++
Sbjct: 520 FYSLEEEHVGFSLDVDEIEK-------------------YQEGEEDQKPPCPRLNEVLME 560

Query: 530 EKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMD 579
            + PEVLQDSLDRCYST S   +L  S Q YRSAFY  E+Q V LA+D+D
Sbjct: 561 AEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDVD 610



 Score =  322 bits (825), Expect = 1e-87
 Identities = 192/396 (48%), Positives = 247/396 (62%), Gaps = 11/396 (2%)

Query: 408 DVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 467
           D D   K +E E+ Q    PR   E+ +  E EV +DSL+ C  T S+     +S QPYG
Sbjct: 225 DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281

Query: 468 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 527
           ++    EE  V  +L    I+     +         E     ++ EE++ P  PR  +E 
Sbjct: 282 NTRITFEEDQVDSTL----IDSSSHDEWLDAVCIIPENESDHEQ-EEEKGPVSPRNLQES 336

Query: 528 LDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEV 587
            +E+ P+   D  D   S P    +++ S Q  RS F+ +E+Q+VGLA+D+      Q  
Sbjct: 337 EEEEAPQESWDEGDWTLSIPP---DMSASYQSDRSTFHSVEEQQVGLALDIGRHWCDQVK 393

Query: 588 EEDQDPSCPRLSGELLDEKEPEVLQESLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRV 647
           +EDQ+ + PRLS ELLDEKEPEVLQ+SLDR YSTP   LEL D CQPYRS FY L++Q +
Sbjct: 394 KEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQPYRSDFYSLQEQHL 453

Query: 648 GLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLG 707
           GLA+D+D ++K QE EEDQ P CPRLSREL +  EPE LQDSL R YSTP  Y ELPD  
Sbjct: 454 GLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRWYSTPFSYPELPDSC 513

Query: 708 QPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDR 767
           QPY S  YSLEE+++G +LDVD I+K QE EEDQ PPCPRL+  L+E  EPEVLQDSLDR
Sbjct: 514 QPYGSCFYSLEEEHVGFSLDVDEIEKYQEGEEDQKPPCPRLNEVLMEAEEPEVLQDSLDR 573

Query: 768 CYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 803
           CYST S+  +   S Q Y S+FY+ EE+ V  +LDV
Sbjct: 574 CYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDV 609



 Score =  318 bits (816), Expect = 1e-86
 Identities = 194/409 (47%), Positives = 241/409 (58%), Gaps = 39/409 (9%)

Query: 335 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSA 394
           DE  K +E E+ Q+   PR   E+   +E EV +DSL  C  T S      +  QPY + 
Sbjct: 227 DEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYGNT 283

Query: 395 VYSLEE--------------QYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPE 440
             + EE              ++L     +   + D E+EE++GP  PR    L E  E E
Sbjct: 284 RITFEEDQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPR---NLQESEEEE 340

Query: 441 VLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRR 500
             Q+S D    T S   +   S Q   S+F+++EE+ VG +LD+G               
Sbjct: 341 APQESWDEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIG--------------- 385

Query: 501 SKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPY 560
               R    +  +EDQ    PRLSRELLDEK PEVLQDSLDR YSTP   LEL D CQPY
Sbjct: 386 ----RHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQPY 441

Query: 561 RSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQESLDRCYS 620
           RS FY L++Q +GLA+D+D ++K QE EEDQ P CPRLS EL +  EPE LQ+SLDR YS
Sbjct: 442 RSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRWYS 501

Query: 621 TPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDE 680
           TP    EL DSCQPY S FY LE++ VG ++D+DEIEKYQE EEDQ P CPRL+  L++ 
Sbjct: 502 TPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEKYQEGEEDQKPPCPRLNEVLMEA 561

Query: 681 KEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD 729
           +EPEVLQDSL RCYST S Y +L    Q Y SA YS EEQ + LALDVD
Sbjct: 562 EEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDVD 610



 Score =  124 bits (310), Expect = 5e-28
 Identities = 92/261 (35%), Positives = 127/261 (48%), Gaps = 39/261 (14%)

Query: 652 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYS 711
           D DE  K +E E+ Q+   PR   E+   +E EV +DSL  C  T S      +  QPY 
Sbjct: 225 DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281

Query: 712 SAVYSLEE--------------QYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVE 757
           +   + EE              ++L     +   + D E+EE++GP  P   R L E  E
Sbjct: 282 NTRITFEEDQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSP---RNLQESEE 338

Query: 758 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 817
            E  Q+S D    T S   +   S Q   S+F+++EE+ VG +LD+G             
Sbjct: 339 EEAPQESWDEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIG------------- 385

Query: 818 RRSKKERRRGRKEGEEDQNPPCPRLNSMLMEVEEPEVLQDSLDICYSTPSMYFELPDSFQ 877
                 R    +  +EDQ    PRL+  L++ +EPEVLQDSLD  YSTP  Y ELPD  Q
Sbjct: 386 ------RHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQ 439

Query: 878 HYRSVFYSFEEEHISFALYVD 898
            YRS FYS +E+H+  AL +D
Sbjct: 440 PYRSDFYSLQEQHLGLALDLD 460


>gi|239741297 PREDICTED: neuroblastoma breakpoint family, member 9
           [Homo sapiens]
          Length = 299

 Score =  410 bits (1054), Expect = e-114
 Identities = 206/218 (94%), Positives = 210/218 (96%)

Query: 1   MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQA 60
           MLRNE QFKEEKLAEQLKQAEELRQYKVLVH+QERELTQLREKLREGRDASRSLNEHLQA
Sbjct: 70  MLRNELQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQA 129

Query: 61  LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR 120
           LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSS+PR
Sbjct: 130 LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPR 189

Query: 121 EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEW 180
           EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEW
Sbjct: 190 EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEW 249

Query: 181 EDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQ 218
           EDAVHIIPENESDDEEEEEKGPVSPR    S E+  P+
Sbjct: 250 EDAVHIIPENESDDEEEEEKGPVSPRTSVGSSEKGGPR 287



 Score = 40.4 bits (93), Expect = 0.008
 Identities = 34/112 (30%), Positives = 47/112 (41%), Gaps = 17/112 (15%)

Query: 652 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYS 711
           D DE  + +  E+ Q  S PR   E+   +E EV +DSL  C  T S      D  QP+ 
Sbjct: 169 DDDEDVQVEVAEKVQKSSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHR 225

Query: 712 SAVYSLEEQYLGLALD--------------VDRIKKDQEEEEDQGPPCPRLS 749
               + EE  +   L               +   + D EEEE++GP  PR S
Sbjct: 226 KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTS 277



 Score = 37.7 bits (86), Expect = 0.050
 Identities = 33/112 (29%), Positives = 48/112 (42%), Gaps = 17/112 (15%)

Query: 577 DMDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQESLDRCYSTPSGCLELTDSCQPYR 636
           D DE  + +  E+ Q  S PR   E+   +E EV ++SL+ C  T S      DS QP+R
Sbjct: 169 DDDEDVQVEVAEKVQKSSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHR 225

Query: 637 SAFYILEQQRVGLAV--------------DMDEIEKYQEVEEDQDPSCPRLS 674
                 E+ +V   +               + E E   E EE++ P  PR S
Sbjct: 226 KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTS 277



 Score = 33.5 bits (75), Expect = 0.93
 Identities = 48/214 (22%), Positives = 85/214 (39%), Gaps = 32/214 (14%)

Query: 335 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSA 394
           +E+ +Y+ +   Q+    +L  +L + ++     +   +   TP          +P  S 
Sbjct: 90  EELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPD---------EPDKSQ 140

Query: 395 VYSLEEQYL-GLALDVDRIKK-----DQEEEED---------QGPPCPRLSRELLEVVEP 439
              L+EQ   G  L    ++K     D +++ED         Q    PR   E+ +  E 
Sbjct: 141 GQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPR---EMQKAEEK 197

Query: 440 EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGR 499
           EV +DSL+ C  T S+     DS QP+  +    EE  V  +L       + +       
Sbjct: 198 EVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIP 257

Query: 500 RSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGP 533
            ++ +      E EE++ P  PR S    ++ GP
Sbjct: 258 ENESD-----DEEEEEKGPVSPRTSVGSSEKGGP 286



 Score = 33.1 bits (74), Expect = 1.2
 Identities = 27/89 (30%), Positives = 40/89 (44%), Gaps = 14/89 (15%)

Query: 281 RELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRV-----GLAVNMD 335
           RE+   +  EV +DSL+ C  T S      DS QP+R      E+ +V     G + +++
Sbjct: 189 REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 248

Query: 336 ---------EIEKYQEVEEDQDPSCPRLS 355
                    E E   E EE++ P  PR S
Sbjct: 249 WEDAVHIIPENESDDEEEEEKGPVSPRTS 277



 Score = 32.3 bits (72), Expect = 2.1
 Identities = 26/89 (29%), Positives = 37/89 (41%), Gaps = 14/89 (15%)

Query: 525 RELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAV-------- 576
           RE+   +  EV +DSL+ C  T S      DS QP+R      E+ +V   +        
Sbjct: 189 REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 248

Query: 577 ------DMDEIEKYQEVEEDQDPSCPRLS 599
                  + E E   E EE++ P  PR S
Sbjct: 249 WEDAVHIIPENESDDEEEEEKGPVSPRTS 277



 Score = 32.0 bits (71), Expect = 2.7
 Identities = 39/163 (23%), Positives = 67/163 (41%), Gaps = 27/163 (16%)

Query: 654 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSA 713
           +E+ +Y+ +   Q+    +L  +L + ++     +   +   TP          +P  S 
Sbjct: 90  EELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPD---------EPDKSQ 140

Query: 714 VYSLEEQYL-GLALDVDRIKK-----DQEEEED---------QGPPCPRLSRELLEVVEP 758
              L+EQ   G  L    ++K     D +++ED         Q    PR   E+ +  E 
Sbjct: 141 GQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPR---EMQKAEEK 197

Query: 759 EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSL 801
           EV +DSL+ C  T S+     DS QP+  +    EE  V  +L
Sbjct: 198 EVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 240



 Score = 30.8 bits (68), Expect = 6.1
 Identities = 22/64 (34%), Positives = 31/64 (48%), Gaps = 3/64 (4%)

Query: 832 EEDQNPPCPRLNSMLMEVEEPEVLQDSLDICYSTPSMYFELPDSFQHYRSVFYSFEEEHI 891
           E+ Q    PR    + + EE EV +DSL+ C  T S      DS Q +R    +FEE+ +
Sbjct: 180 EKVQKSSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKV 236

Query: 892 SFAL 895
              L
Sbjct: 237 DSTL 240


>gi|221136844 neuroblastoma breakpoint family, member 6 isoform 1
           [Homo sapiens]
          Length = 667

 Score =  399 bits (1026), Expect = e-111
 Identities = 236/434 (54%), Positives = 293/434 (67%), Gaps = 27/434 (6%)

Query: 1   MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQA 60
           +LR+E Q   EKLAE+L+QAEELRQYK LVH+Q +ELTQLREKLREGRDASR LN+HL+ 
Sbjct: 71  VLRDELQ-SMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDASRWLNKHLKT 129

Query: 61  LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDV--QVEVAEKVQKSSA 118
           LLTPD+PDKSQGQDL+EQLAEG RLA+HLV KLSPEND D+DED   + E  EKVQ+S A
Sbjct: 130 LLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDEEVEKVQESPA 189

Query: 119 PREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHV 178
           PRE+QK EEKEVP+DSLEECA+TCSNSH P +SNQPHR TKITF+E +VDS L+  S H 
Sbjct: 190 PREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVDSALVVESEHP 249

Query: 179 --EWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQES---WDEGYSTLSIP-- 231
             E E+A++I PEN++D EEEE K PV PRN Q  E  E+            S ++ P  
Sbjct: 250 HDEEEEALNIPPENQNDHEEEEGKAPVPPRNRQSLEPGELTNLRDFLISPVVSHVANPGH 309

Query: 232 PEMLASYKSYSSTFHSLEEQQVCMAVDIGRH----RWDQV------KKED------HEAT 275
            +   SY+    +F +L+EQ+VC A D+ R     +WD+       K+ D       E  
Sbjct: 310 HDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVKGQETV 369

Query: 276 GPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVNMD 335
            PRLSR  L     E+ Q+SLD C  TPS   +LT S  PY S  Y  E ++V LA+ +D
Sbjct: 370 APRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLAL-VD 428

Query: 336 EIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAV 395
           +I+K QE  EDQ P CPRLS+EL + KE EV +DS+   Y TPS + ++ D  QPYSS +
Sbjct: 429 KIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQPYSSTL 488

Query: 396 YSLEEQYLGLALDV 409
            SLE+Q    ALDV
Sbjct: 489 SSLEDQLACSALDV 502



 Score =  147 bits (372), Expect = 3e-35
 Identities = 153/511 (29%), Positives = 242/511 (47%), Gaps = 99/511 (19%)

Query: 13  LAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQG 72
           LA QLK+ +   +YK ++ +  R+  Q  EKL E    +  L ++ +AL+     + +Q 
Sbjct: 52  LANQLKKYK-CEEYKDIIDSVLRDELQSMEKLAEKLRQAEELRQY-KALVHSQAKELTQ- 108

Query: 73  QDLQEQLAEGCR----LAQHLVQKLSPEN-DNDDDEDVQVEVAEKVQKSSAPREMQKAEE 127
             L+E+L EG      L +HL   L+P++ D    +D++ ++AE        R  +    
Sbjct: 109 --LREKLREGRDASRWLNKHLKTLLTPDDPDKSQGQDLREQLAE------GHRLAEHLVH 160

Query: 128 KEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHII 187
           K  PE+  +E                         +ED                      
Sbjct: 161 KLSPENDEDE-------------------------DED---------------------- 173

Query: 188 PENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYKSYSSTFHS 247
            E++ D+E E+ +   +PR +Q++EE+EVPQ+S +E   T S       S + + ST  +
Sbjct: 174 -EDDKDEEVEKVQESPAPREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKIT 232

Query: 248 LEEQQVCMAVDI-GRHRWDQVKK---------EDHE-----ATGPRLSRELLDEKGPEVL 292
            +E +V  A+ +   H  D+ ++          DHE     A  P  +R+ L+      L
Sbjct: 233 FKEHEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRNRQSLEPGELTNL 292

Query: 293 QDSLDR---CYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVNM---------DE---- 336
           +D L      +    G  + ++S +    +F  L++Q+V  A ++         DE    
Sbjct: 293 RDFLISPVVSHVANPGHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLG 352

Query: 337 -IEKYQEVEE--DQDPSCPRLSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSS 393
            +EK  ++EE   Q+   PRLSR  L   + E+ Q+SL  C  TPS   +L     PY S
Sbjct: 353 FLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWS 412

Query: 394 AVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTP 453
            +YS E++ + LAL VD+IKKDQEE EDQ PPCPRLS+EL EV E EV +DS++  Y TP
Sbjct: 413 TLYSFEDKQVSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTP 471

Query: 454 SSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 484
           S   +  D  QPY S+  +LE++    +LDV
Sbjct: 472 SVHHDVSDCHQPYSSTLSSLEDQLACSALDV 502



 Score =  137 bits (344), Expect = 6e-32
 Identities = 117/332 (35%), Positives = 164/332 (49%), Gaps = 46/332 (13%)

Query: 510 KEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQ 569
           +E E+ Q  P PR   E+   +  EV QDSL+ C  T S     ++S QP+RS     ++
Sbjct: 179 EEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKE 235

Query: 570 QRVGLAVDMD----------------EIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQE 613
             V  A+ ++                E +   E EE + P  PR    L    EP  L  
Sbjct: 236 HEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRNRQSL----EPGELTN 291

Query: 614 SLDRCYS------TPSGCLELTDSCQPYRSAFYILEQQRVGLAVDM---------DE--- 655
             D   S         G  + ++S +    +F  L++Q+V  A D+         DE   
Sbjct: 292 LRDFLISPVVSHVANPGHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSL 351

Query: 656 --IEKYQEVEE--DQDPSCPRLSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYS 711
             +EK  ++EE   Q+   PRLSR  L   + E+ Q+SL  C  TPS   +L     PY 
Sbjct: 352 GFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYW 411

Query: 712 SAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYST 771
           S +YS E++ + LAL VD+IKKDQEE EDQ PPCPRLS+EL EV E EV +DS++  Y T
Sbjct: 412 STLYSFEDKQVSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLT 470

Query: 772 PSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 803
           PS   +  D  QPY S+  +LE++    +LDV
Sbjct: 471 PSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 502



 Score =  122 bits (307), Expect = 1e-27
 Identities = 111/356 (31%), Positives = 167/356 (46%), Gaps = 59/356 (16%)

Query: 577 DMDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQESLDRCYSTPSGCLELTDSCQPYR 636
           D DE +K +EVE+ Q+   PR   E+   +E EV Q+SL+ C  T S     ++S QP+R
Sbjct: 171 DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227

Query: 637 SAFYILEQQRVGLAVDMD----------------EIEKYQEVEEDQDPSCPRLSRELLDE 680
           S     ++  V  A+ ++                E +   E EE + P  PR +R+ L+ 
Sbjct: 228 STKITFKEHEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPR-NRQSLEP 286

Query: 681 KEPEVLQDSLGR---CYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRI------ 731
            E   L+D L      +    G+ +  +  +    +  +L+EQ +  A DV R       
Sbjct: 287 GELTNLRDFLISPVVSHVANPGHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKW 346

Query: 732 ----------KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDS 781
                     + D EE + Q    PRLSR  L V + E+ Q+SLD C  TPS   +   S
Sbjct: 347 DETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPS 406

Query: 782 CQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPR 841
             PY S+ Y+ E+K V  +L V +I+K                    +E  EDQ+PPCPR
Sbjct: 407 YHPYWSTLYSFEDKQVSLAL-VDKIKKD-------------------QEEIEDQSPPCPR 446

Query: 842 LNSMLMEVEEPEVLQDSLDICYSTPSMYFELPDSFQHYRSVFYSFEEEHISFALYV 897
           L+  L EV+E EV +DS++  Y TPS++ ++ D  Q Y S   S E++    AL V
Sbjct: 447 LSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 502



 Score = 39.3 bits (90), Expect = 0.017
 Identities = 26/71 (36%), Positives = 38/71 (53%), Gaps = 3/71 (4%)

Query: 829 KEGEEDQNPPCPRLNSMLMEVEEPEVLQDSLDICYSTPSMYFELPDSFQHYRSVFYSFEE 888
           +E E+ Q  P PR    + + EE EV QDSL+ C  T S      +S Q +RS   +F+E
Sbjct: 179 EEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKE 235

Query: 889 EHISFALYVDN 899
             +  AL V++
Sbjct: 236 HEVDSALVVES 246


>gi|221136848 neuroblastoma breakpoint family, member 6 isoform 2
           [Homo sapiens]
          Length = 638

 Score =  395 bits (1016), Expect = e-110
 Identities = 231/429 (53%), Positives = 286/429 (66%), Gaps = 46/429 (10%)

Query: 1   MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQA 60
           +LR+E Q   EKLAE+L+QAEELRQYK LVH+Q +ELTQLREKLREGRDASR LN+HL+ 
Sbjct: 71  VLRDELQ-SMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDASRWLNKHLKT 129

Query: 61  LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDV--QVEVAEKVQKSSA 118
           LLTPD+PDKSQGQDL+EQLAEG RLA+HLV KLSPEND D+DED   + E  EKVQ+S A
Sbjct: 130 LLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDEEVEKVQESPA 189

Query: 119 PREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHV 178
           PRE+QK EEKEVP+DSLEECA+TCSNSH P +SNQPHR TKITF+E +VDS L+  S H 
Sbjct: 190 PREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVDSALVVESEHP 249

Query: 179 --EWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLA 236
             E E+A++I PEN++D EEEE K PV PR+  +S                         
Sbjct: 250 HDEEEEALNIPPENQNDHEEEEGKAPVPPRHHDKSN------------------------ 285

Query: 237 SYKSYSSTFHSLEEQQVCMAVDIGRH----RWDQV------KKED------HEATGPRLS 280
           SY+    +F +L+EQ+VC A D+ R     +WD+       K+ D       E   PRLS
Sbjct: 286 SYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVKGQETVAPRLS 345

Query: 281 RELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVNMDEIEKY 340
           R  L     E+ Q+SLD C  TPS   +LT S  PY S  Y  E ++V LA+ +D+I+K 
Sbjct: 346 RGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLAL-VDKIKKD 404

Query: 341 QEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEE 400
           QE  EDQ P CPRLS+EL + KE EV +DS+   Y TPS + ++ D  QPYSS + SLE+
Sbjct: 405 QEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQPYSSTLSSLED 464

Query: 401 QYLGLALDV 409
           Q    ALDV
Sbjct: 465 QLACSALDV 473



 Score =  146 bits (368), Expect = 1e-34
 Identities = 147/494 (29%), Positives = 235/494 (47%), Gaps = 94/494 (19%)

Query: 13  LAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQG 72
           LA QLK+ +   +YK ++ +  R+  Q  EKL E    +  L ++ +AL+     + +Q 
Sbjct: 52  LANQLKKYK-CEEYKDIIDSVLRDELQSMEKLAEKLRQAEELRQY-KALVHSQAKELTQ- 108

Query: 73  QDLQEQLAEGCR----LAQHLVQKLSPEN-DNDDDEDVQVEVAEKVQKSSAPREMQKAEE 127
             L+E+L EG      L +HL   L+P++ D    +D++ ++AE        R  +    
Sbjct: 109 --LREKLREGRDASRWLNKHLKTLLTPDDPDKSQGQDLREQLAE------GHRLAEHLVH 160

Query: 128 KEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHII 187
           K  PE+  +E                         +ED                      
Sbjct: 161 KLSPENDEDE-------------------------DED---------------------- 173

Query: 188 PENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYKSYSSTFHS 247
            E++ D+E E+ +   +PR +Q++EE+EVPQ+S +E   T S       S + + ST  +
Sbjct: 174 -EDDKDEEVEKVQESPAPREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKIT 232

Query: 248 LEEQQVCMAVDI-GRHRWDQVKKEDHEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGC 306
            +E +V  A+ +   H  D+  +E+     P    +  +E+G   +          P   
Sbjct: 233 FKEHEVDSALVVESEHPHDE--EEEALNIPPENQNDHEEEEGKAPV----------PPRH 280

Query: 307 LELTDSCQPYRSAFYVLEQQRVGLAVNM---------DE-----IEKYQEVEE--DQDPS 350
            + ++S +    +F  L++Q+V  A ++         DE     +EK  ++EE   Q+  
Sbjct: 281 HDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVKGQETV 340

Query: 351 CPRLSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD 410
            PRLSR  L   + E+ Q+SL  C  TPS   +L     PY S +YS E++ + LAL VD
Sbjct: 341 APRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLAL-VD 399

Query: 411 RIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSF 470
           +IKKDQEE EDQ PPCPRLS+EL EV E EV +DS++  Y TPS   +  D  QPY S+ 
Sbjct: 400 KIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQPYSSTL 459

Query: 471 YALEEKHVGFSLDV 484
            +LE++    +LDV
Sbjct: 460 SSLEDQLACSALDV 473



 Score =  138 bits (348), Expect = 2e-32
 Identities = 109/310 (35%), Positives = 159/310 (51%), Gaps = 31/310 (10%)

Query: 510 KEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQ 569
           +E E+ Q  P PR   E+   +  EV QDSL+ C  T S     ++S QP+RS     ++
Sbjct: 179 EEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKE 235

Query: 570 QRVGLAVDMDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQESLDRCYSTPSGCLELT 629
             V  A+ ++    + E EE  +      +    +E +  V     D+           +
Sbjct: 236 HEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRHHDK-----------S 284

Query: 630 DSCQPYRSAFYILEQQRVGLAVDM---------DE-----IEKYQEVEE--DQDPSCPRL 673
           +S +    +F  L++Q+V  A D+         DE     +EK  ++EE   Q+   PRL
Sbjct: 285 NSYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVKGQETVAPRL 344

Query: 674 SRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKK 733
           SR  L   + E+ Q+SL  C  TPS   +L     PY S +YS E++ + LAL VD+IKK
Sbjct: 345 SRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLAL-VDKIKK 403

Query: 734 DQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALE 793
           DQEE EDQ PPCPRLS+EL EV E EV +DS++  Y TPS   +  D  QPY S+  +LE
Sbjct: 404 DQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQPYSSTLSSLE 463

Query: 794 EKHVGFSLDV 803
           ++    +LDV
Sbjct: 464 DQLACSALDV 473



 Score =  122 bits (306), Expect = 2e-27
 Identities = 105/334 (31%), Positives = 161/334 (48%), Gaps = 44/334 (13%)

Query: 577 DMDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQESLDRCYSTPSGCLELTDSCQPYR 636
           D DE +K +EVE+ Q+   PR   E+   +E EV Q+SL+ C  T S     ++S QP+R
Sbjct: 171 DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227

Query: 637 SAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKE-----PEVLQDSLG 691
           S     ++  V  A+ ++   ++   EE++  + P  ++   +E+E     P    D   
Sbjct: 228 STKITFKEHEVDSALVVES--EHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRHHDKSN 285

Query: 692 RCYSTPSGYLELP--------DLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGP 743
                   +L L         D+ + YS+  +  +E  LG        + D EE + Q  
Sbjct: 286 SYRHREVSFLALDEQKVCSAQDVARDYSNPKW--DETSLGFL----EKQSDLEEVKGQET 339

Query: 744 PCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 803
             PRLSR  L V + E+ Q+SLD C  TPS   +   S  PY S+ Y+ E+K V  +L V
Sbjct: 340 VAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLAL-V 398

Query: 804 GEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNSMLMEVEEPEVLQDSLDICY 863
            +I+K                    +E  EDQ+PPCPRL+  L EV+E EV +DS++  Y
Sbjct: 399 DKIKKD-------------------QEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVY 439

Query: 864 STPSMYFELPDSFQHYRSVFYSFEEEHISFALYV 897
            TPS++ ++ D  Q Y S   S E++    AL V
Sbjct: 440 LTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 473



 Score = 39.3 bits (90), Expect = 0.017
 Identities = 26/71 (36%), Positives = 38/71 (53%), Gaps = 3/71 (4%)

Query: 829 KEGEEDQNPPCPRLNSMLMEVEEPEVLQDSLDICYSTPSMYFELPDSFQHYRSVFYSFEE 888
           +E E+ Q  P PR    + + EE EV QDSL+ C  T S      +S Q +RS   +F+E
Sbjct: 179 EEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKE 235

Query: 889 EHISFALYVDN 899
             +  AL V++
Sbjct: 236 HEVDSALVVES 246


>gi|221218991 neuroblastoma breakpoint family, member 4 [Homo
           sapiens]
          Length = 638

 Score =  395 bits (1016), Expect = e-110
 Identities = 231/429 (53%), Positives = 286/429 (66%), Gaps = 46/429 (10%)

Query: 1   MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQA 60
           +LR+E Q   EKLAE+L+QAEELRQYK LVH+Q +ELTQLREKLREGRDASR LN+HL+ 
Sbjct: 71  VLRDELQ-SMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDASRWLNKHLKT 129

Query: 61  LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDV--QVEVAEKVQKSSA 118
           LLTPD+PDKSQGQDL+EQLAEG RLA+HLV KLSPEND D+DED   + E  EKVQ+S A
Sbjct: 130 LLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDEEVEKVQESPA 189

Query: 119 PREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHV 178
           PRE+QK EEKEVP+DSLEECA+TCSNSH P +SNQPHR TKITF+E +VDS L+  S H 
Sbjct: 190 PREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVDSALVVESEHP 249

Query: 179 --EWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLA 236
             E E+A++I PEN++D EEEE K PV PR+  +S                         
Sbjct: 250 HDEEEEALNIPPENQNDHEEEEGKAPVPPRHHDKSN------------------------ 285

Query: 237 SYKSYSSTFHSLEEQQVCMAVDIGRH----RWDQV------KKED------HEATGPRLS 280
           SY+    +F +L+EQ+VC A D+ R     +WD+       K+ D       E   PRLS
Sbjct: 286 SYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVKGQETVAPRLS 345

Query: 281 RELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVNMDEIEKY 340
           R  L     E+ Q+SLD C  TPS   +LT S  PY S  Y  E ++V LA+ +D+I+K 
Sbjct: 346 RGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLAL-VDKIKKD 404

Query: 341 QEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEE 400
           QE  EDQ P CPRLS+EL + KE EV +DS+   Y TPS + ++ D  QPYSS + SLE+
Sbjct: 405 QEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQPYSSTLSSLED 464

Query: 401 QYLGLALDV 409
           Q    ALDV
Sbjct: 465 QLACSALDV 473



 Score =  146 bits (368), Expect = 1e-34
 Identities = 147/494 (29%), Positives = 235/494 (47%), Gaps = 94/494 (19%)

Query: 13  LAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQG 72
           LA QLK+ +   +YK ++ +  R+  Q  EKL E    +  L ++ +AL+     + +Q 
Sbjct: 52  LANQLKKYK-CEEYKDIIDSVLRDELQSMEKLAEKLRQAEELRQY-KALVHSQAKELTQ- 108

Query: 73  QDLQEQLAEGCR----LAQHLVQKLSPEN-DNDDDEDVQVEVAEKVQKSSAPREMQKAEE 127
             L+E+L EG      L +HL   L+P++ D    +D++ ++AE        R  +    
Sbjct: 109 --LREKLREGRDASRWLNKHLKTLLTPDDPDKSQGQDLREQLAE------GHRLAEHLVH 160

Query: 128 KEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHII 187
           K  PE+  +E                         +ED                      
Sbjct: 161 KLSPENDEDE-------------------------DED---------------------- 173

Query: 188 PENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYKSYSSTFHS 247
            E++ D+E E+ +   +PR +Q++EE+EVPQ+S +E   T S       S + + ST  +
Sbjct: 174 -EDDKDEEVEKVQESPAPREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKIT 232

Query: 248 LEEQQVCMAVDI-GRHRWDQVKKEDHEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGC 306
            +E +V  A+ +   H  D+  +E+     P    +  +E+G   +          P   
Sbjct: 233 FKEHEVDSALVVESEHPHDE--EEEALNIPPENQNDHEEEEGKAPV----------PPRH 280

Query: 307 LELTDSCQPYRSAFYVLEQQRVGLAVNM---------DE-----IEKYQEVEE--DQDPS 350
            + ++S +    +F  L++Q+V  A ++         DE     +EK  ++EE   Q+  
Sbjct: 281 HDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVKGQETV 340

Query: 351 CPRLSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD 410
            PRLSR  L   + E+ Q+SL  C  TPS   +L     PY S +YS E++ + LAL VD
Sbjct: 341 APRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLAL-VD 399

Query: 411 RIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSF 470
           +IKKDQEE EDQ PPCPRLS+EL EV E EV +DS++  Y TPS   +  D  QPY S+ 
Sbjct: 400 KIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQPYSSTL 459

Query: 471 YALEEKHVGFSLDV 484
            +LE++    +LDV
Sbjct: 460 SSLEDQLACSALDV 473



 Score =  138 bits (348), Expect = 2e-32
 Identities = 109/310 (35%), Positives = 159/310 (51%), Gaps = 31/310 (10%)

Query: 510 KEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQ 569
           +E E+ Q  P PR   E+   +  EV QDSL+ C  T S     ++S QP+RS     ++
Sbjct: 179 EEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKE 235

Query: 570 QRVGLAVDMDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQESLDRCYSTPSGCLELT 629
             V  A+ ++    + E EE  +      +    +E +  V     D+           +
Sbjct: 236 HEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRHHDK-----------S 284

Query: 630 DSCQPYRSAFYILEQQRVGLAVDM---------DE-----IEKYQEVEE--DQDPSCPRL 673
           +S +    +F  L++Q+V  A D+         DE     +EK  ++EE   Q+   PRL
Sbjct: 285 NSYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVKGQETVAPRL 344

Query: 674 SRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKK 733
           SR  L   + E+ Q+SL  C  TPS   +L     PY S +YS E++ + LAL VD+IKK
Sbjct: 345 SRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLAL-VDKIKK 403

Query: 734 DQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALE 793
           DQEE EDQ PPCPRLS+EL EV E EV +DS++  Y TPS   +  D  QPY S+  +LE
Sbjct: 404 DQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQPYSSTLSSLE 463

Query: 794 EKHVGFSLDV 803
           ++    +LDV
Sbjct: 464 DQLACSALDV 473



 Score =  122 bits (306), Expect = 2e-27
 Identities = 105/334 (31%), Positives = 161/334 (48%), Gaps = 44/334 (13%)

Query: 577 DMDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQESLDRCYSTPSGCLELTDSCQPYR 636
           D DE +K +EVE+ Q+   PR   E+   +E EV Q+SL+ C  T S     ++S QP+R
Sbjct: 171 DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227

Query: 637 SAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKE-----PEVLQDSLG 691
           S     ++  V  A+ ++   ++   EE++  + P  ++   +E+E     P    D   
Sbjct: 228 STKITFKEHEVDSALVVES--EHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRHHDKSN 285

Query: 692 RCYSTPSGYLELP--------DLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGP 743
                   +L L         D+ + YS+  +  +E  LG        + D EE + Q  
Sbjct: 286 SYRHREVSFLALDEQKVCSAQDVARDYSNPKW--DETSLGFL----EKQSDLEEVKGQET 339

Query: 744 PCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 803
             PRLSR  L V + E+ Q+SLD C  TPS   +   S  PY S+ Y+ E+K V  +L V
Sbjct: 340 VAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLAL-V 398

Query: 804 GEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNSMLMEVEEPEVLQDSLDICY 863
            +I+K                    +E  EDQ+PPCPRL+  L EV+E EV +DS++  Y
Sbjct: 399 DKIKKD-------------------QEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVY 439

Query: 864 STPSMYFELPDSFQHYRSVFYSFEEEHISFALYV 897
            TPS++ ++ D  Q Y S   S E++    AL V
Sbjct: 440 LTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 473



 Score = 39.3 bits (90), Expect = 0.017
 Identities = 26/71 (36%), Positives = 38/71 (53%), Gaps = 3/71 (4%)

Query: 829 KEGEEDQNPPCPRLNSMLMEVEEPEVLQDSLDICYSTPSMYFELPDSFQHYRSVFYSFEE 888
           +E E+ Q  P PR    + + EE EV QDSL+ C  T S      +S Q +RS   +F+E
Sbjct: 179 EEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKE 235

Query: 889 EHISFALYVDN 899
             +  AL V++
Sbjct: 236 HEVDSALVVES 246


>gi|114158664 hypothetical protein LOC343505 [Homo sapiens]
          Length = 421

 Score =  335 bits (859), Expect = 1e-91
 Identities = 178/269 (66%), Positives = 209/269 (77%), Gaps = 10/269 (3%)

Query: 1   MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQA 60
           MLR E QFKEEKLAEQLKQAEELRQYKVLVH+QEREL QLREKLREGRDAS SLN+HLQA
Sbjct: 90  MLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELIQLREKLREGRDASHSLNQHLQA 149

Query: 61  LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR 120
           LLTPD+ D SQGQD +EQLAEGCRLA+HLV KLSPEND D+DE+ + +  +KVQ+S APR
Sbjct: 150 LLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPENDTDEDENDKTKELDKVQESPAPR 209

Query: 121 EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLI--GSSSHV 178
           E QKAEEKEVPEDSLEECAIT SNSHGP DSN PH+  KIT EEDKV+S L+    SS  
Sbjct: 210 EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQD 269

Query: 179 EWEDAVHIIPENESDDEEEEEKGPVSPR--------NLQESEEEEVPQESWDEGYSTLSI 230
           EW+DA++I+ EN++DDEEEE K PV P+         LQESEE+EV Q+S +E  +T   
Sbjct: 270 EWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCS 329

Query: 231 PPEMLASYKSYSSTFHSLEEQQVCMAVDI 259
             ++  SY+    TF +L EQ+VC A D+
Sbjct: 330 DHDVSQSYQPCEGTFLALVEQKVCSAQDV 358



 Score = 60.8 bits (146), Expect = 5e-09
 Identities = 58/209 (27%), Positives = 91/209 (43%), Gaps = 27/209 (12%)

Query: 627 ELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 686
           +L + C+  R   + L  +      D DE +K +E+++ Q+   PR  ++    +E EV 
Sbjct: 167 QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220

Query: 687 QDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 730
           +DSL  C  T S      D   P+ +   + EE  +   L VD                 
Sbjct: 221 EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280

Query: 731 IKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 785
            + D EEEE + P  P+++      +L E  E EVLQDS +   +T  S  +   S QP 
Sbjct: 281 NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340

Query: 786 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 814
             +F AL E+ V  + DV       KG++
Sbjct: 341 EGTFLALVEQKVCSAQDVASEHSNSKGEE 369



 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 57/209 (27%), Positives = 91/209 (43%), Gaps = 27/209 (12%)

Query: 308 ELTDSCQPYRSAFYVLEQQRVGLAVNMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 367
           +L + C+  R   + L  +      + DE +K +E+++ Q+   PR  ++    +E EV 
Sbjct: 167 QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220

Query: 368 QDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 411
           +DSL  C  T S      D   P+ +   + EE  +   L VD                 
Sbjct: 221 EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280

Query: 412 IKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 466
            + D EEEE + P  P+++      +L E  E EVLQDS +   +T  S  +   S QP 
Sbjct: 281 NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340

Query: 467 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 495
             +F AL E+ V  + DV       KG++
Sbjct: 341 EGTFLALVEQKVCSAQDVASEHSNSKGEE 369



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 54/209 (25%), Positives = 91/209 (43%), Gaps = 27/209 (12%)

Query: 552 ELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVL 611
           +L + C+  R   + L  +      D DE +K +E+++ Q+   PR   E    +E EV 
Sbjct: 167 QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPR---EEQKAEEKEVP 220

Query: 612 QESLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVG--LAVDMD--------------E 655
           ++SL+ C  T S     +DS  P+++     E+ +V   L VD +              E
Sbjct: 221 EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280

Query: 656 IEKYQEVEEDQDPSCPRLS-----RELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPY 710
            +   E EE + P  P+++      +L + +E EVLQDS     +T     ++    QP 
Sbjct: 281 NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340

Query: 711 SSAVYSLEEQYLGLALDVDRIKKDQEEEE 739
                +L EQ +  A DV     + + EE
Sbjct: 341 EGTFLALVEQKVCSAQDVASEHSNSKGEE 369



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 55/207 (26%), Positives = 92/207 (44%), Gaps = 38/207 (18%)

Query: 510 KEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQ 569
           KE ++ Q  P PR  ++  +++ PE   DSL+ C  T S     +DS  P+++     E+
Sbjct: 197 KELDKVQESPAPREEQKAEEKEVPE---DSLEECAITYSNSHGPSDSNPPHKNIKITSEE 253

Query: 570 QRVG--LAVDMD--------------EIEKYQEVEEDQDPSCPRLSG-----ELLDEKEP 608
            +V   L VD +              E +   E EE + P  P+++      +L + +E 
Sbjct: 254 DKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQESEEK 313

Query: 609 EVLQESLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEED--- 665
           EVLQ+S +   +T     +++ S QP    F  L +Q+V  A D+       + EE    
Sbjct: 314 EVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEHSNSKGEETPLG 373

Query: 666 --------QDPSCPRLSRE---LLDEK 681
                   +D    R+S++   LLDEK
Sbjct: 374 FPDTKYCWKDEKDERMSQKVAFLLDEK 400



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 51/217 (23%), Positives = 95/217 (43%), Gaps = 42/217 (19%)

Query: 188 PENESDDEEEEEKGPV-------SPRNLQESEEEEVPQESWDE---GYSTLSIPPEMLAS 237
           PEN++D++E ++   +       +PR  Q++EE+EVP++S +E    YS    P +    
Sbjct: 184 PENDTDEDENDKTKELDKVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPP 243

Query: 238 YKSYSSTFHSLEEQQVCMA-VDIGRHRWDQV-------KKEDHEATG-----PRLSR--- 281
           +K+   T    +   + +   +  +  W          + +D E  G     P+++    
Sbjct: 244 HKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWIC 303

Query: 282 --ELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVNMDEIEK 339
             +L + +  EVLQDS +   +T     +++ S QP    F  L +Q+V  A ++     
Sbjct: 304 GLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEHS 363

Query: 340 YQEVEED-----------QDPSCPRLSRE---LLDEK 362
             + EE            +D    R+S++   LLDEK
Sbjct: 364 NSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400



 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 47/173 (27%), Positives = 73/173 (42%), Gaps = 11/173 (6%)

Query: 727 DVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 786
           D D   K +E ++ Q  P PR   E  +  E EV +DSL+ C  T S+     DS  P+ 
Sbjct: 189 DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245

Query: 787 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNSM- 845
           +     EE  V   L V   + +    + +   +     +   E EE + P  P++    
Sbjct: 246 NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302

Query: 846 ----LMEVEEPEVLQDSLDICYSTPSMYFELPDSFQHYRSVFYSFEEEHISFA 894
               L E EE EVLQDS +   +T     ++  S+Q     F +  E+ +  A
Sbjct: 303 CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSA 355



 Score = 33.9 bits (76), Expect = 0.72
 Identities = 23/71 (32%), Positives = 37/71 (52%), Gaps = 3/71 (4%)

Query: 829 KEGEEDQNPPCPRLNSMLMEVEEPEVLQDSLDICYSTPSMYFELPDSFQHYRSVFYSFEE 888
           KE ++ Q  P PR      + EE EV +DSL+ C  T S      DS   ++++  + EE
Sbjct: 197 KELDKVQESPAPREEQ---KAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEE 253

Query: 889 EHISFALYVDN 899
           + ++  L VD+
Sbjct: 254 DKVNSILVVDS 264


>gi|239758011 PREDICTED: hypothetical protein LOC728841, partial
           [Homo sapiens]
          Length = 166

 Score =  231 bits (589), Expect = 2e-60
 Identities = 112/144 (77%), Positives = 124/144 (86%)

Query: 776 LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQ 835
           LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKK+RRRGRKEGEEDQ
Sbjct: 1   LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQ 60

Query: 836 NPPCPRLNSMLMEVEEPEVLQDSLDICYSTPSMYFELPDSFQHYRSVFYSFEEEHISFAL 895
           NPPCPRL+  L++ +EPEVLQDSLD CYSTPS Y ELPD  Q Y S  YS EE+++  AL
Sbjct: 61  NPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 120

Query: 896 YVDNRFFTLTVTSLHLVFQMGVIF 919
            VD+ + T+ V SLHLVFQ+GVIF
Sbjct: 121 DVDSEYLTMKVISLHLVFQIGVIF 144



 Score =  223 bits (569), Expect = 5e-58
 Identities = 109/123 (88%), Positives = 114/123 (92%)

Query: 457 LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQ 516
           LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKK+RRRGRKEGEEDQ
Sbjct: 1   LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQ 60

Query: 517 NPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAV 576
           NPPCPRLSRELLDEK PEVLQDSLDRCYSTPSG LEL D  QPY SA Y LE+Q +GLA+
Sbjct: 61  NPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 120

Query: 577 DMD 579
           D+D
Sbjct: 121 DVD 123



 Score =  163 bits (413), Expect = 6e-40
 Identities = 85/123 (69%), Positives = 93/123 (75%), Gaps = 19/123 (15%)

Query: 626 LELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKY-------------------QEVEEDQ 666
           LE  DSCQPY S+FY LE++ VG ++D+ EIEK                    +E EEDQ
Sbjct: 1   LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQ 60

Query: 667 DPSCPRLSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 726
           +P CPRLSRELLDEKEPEVLQDSL RCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL
Sbjct: 61  NPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 120

Query: 727 DVD 729
           DVD
Sbjct: 121 DVD 123



 Score =  162 bits (409), Expect = 2e-39
 Identities = 84/123 (68%), Positives = 93/123 (75%), Gaps = 19/123 (15%)

Query: 307 LELTDSCQPYRSAFYVLEQQRVGLAVNMDEIEKY-------------------QEVEEDQ 347
           LE  DSCQPY S+FY LE++ VG ++++ EIEK                    +E EEDQ
Sbjct: 1   LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQ 60

Query: 348 DPSCPRLSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 407
           +P CPRLSRELLDEKEPEVLQDSL RCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL
Sbjct: 61  NPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 120

Query: 408 DVD 410
           DVD
Sbjct: 121 DVD 123



 Score =  135 bits (340), Expect = 2e-31
 Identities = 72/123 (58%), Positives = 85/123 (69%), Gaps = 19/123 (15%)

Query: 551 LELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKY-------------------QEVEEDQ 591
           LE  DSCQPY S+FY LE++ VG ++D+ EIEK                    +E EEDQ
Sbjct: 1   LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQ 60

Query: 592 DPSCPRLSGELLDEKEPEVLQESLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAV 651
           +P CPRLS ELLDEKEPEVLQ+SLDRCYSTPSG LEL D  QPY SA Y LE+Q +GLA+
Sbjct: 61  NPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 120

Query: 652 DMD 654
           D+D
Sbjct: 121 DVD 123



 Score =  128 bits (321), Expect = 3e-29
 Identities = 67/122 (54%), Positives = 82/122 (67%), Gaps = 19/122 (15%)

Query: 382 LELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKD-------------------QEEEEDQ 422
           LE PD  QPY S+ Y+LEE+++G +LDV  I+K                    +E EEDQ
Sbjct: 1   LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQ 60

Query: 423 GPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSL 482
            PPCPRLSRELL+  EPEVLQDSLDRCYSTPS  LE PD  QPY S+ Y+LEE+++G +L
Sbjct: 61  NPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 120

Query: 483 DV 484
           DV
Sbjct: 121 DV 122



 Score =  128 bits (321), Expect = 3e-29
 Identities = 67/122 (54%), Positives = 82/122 (67%), Gaps = 19/122 (15%)

Query: 701 LELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKD-------------------QEEEEDQ 741
           LE PD  QPY S+ Y+LEE+++G +LDV  I+K                    +E EEDQ
Sbjct: 1   LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQ 60

Query: 742 GPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSL 801
            PPCPRLSRELL+  EPEVLQDSLDRCYSTPS  LE PD  QPY S+ Y+LEE+++G +L
Sbjct: 61  NPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 120

Query: 802 DV 803
           DV
Sbjct: 121 DV 122



 Score =  104 bits (259), Expect = 4e-22
 Identities = 59/118 (50%), Positives = 74/118 (62%), Gaps = 19/118 (16%)

Query: 237 SYKSYSSTFHSLEEQQVCMAVDIG-------------------RHRWDQVKKEDHEATGP 277
           S + Y S+F++LEE+ V  ++D+G                   R R  +  +ED     P
Sbjct: 6   SCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQNPPCP 65

Query: 278 RLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVNMD 335
           RLSRELLDEK PEVLQDSLDRCYSTPSG LEL D  QPY SA Y LE+Q +GLA+++D
Sbjct: 66  RLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD 123



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 28/68 (41%), Positives = 40/68 (58%), Gaps = 3/68 (4%)

Query: 195 EEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTLSIPPEMLASYKSYSSTFHSLEEQ 251
           E EE++ P  PR    L + +E EV Q+S D  YST S   E+    + YSS  +SLEEQ
Sbjct: 55  EGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQ 114

Query: 252 QVCMAVDI 259
            + +A+D+
Sbjct: 115 YLGLALDV 122


>gi|157311604 phosphodiesterase 4D interacting protein isoform 1 [Homo
            sapiens]
          Length = 2346

 Score = 78.2 bits (191), Expect = 3e-14
 Identities = 57/182 (31%), Positives = 96/182 (52%), Gaps = 14/182 (7%)

Query: 10   EEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEH-------LQALL 62
            EEKLAE+L+ A    +Y  L+  Q REL+ LR+K+REGR     +  H        + LL
Sbjct: 1458 EEKLAEELRSASWPGKYDSLIQDQARELSYLRQKIREGRGICYLITRHAKDTVKSFEDLL 1517

Query: 63   TPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVE-VAEKVQKSSAPRE 121
              ++ D   GQ  +EQLA+G +L + L  KLS ++   + +   +E +A ++      RE
Sbjct: 1518 RSNDIDYYLGQSFREQLAQGSQLTERLTSKLSTKDHKSEKDQAGLEPLALRLS-----RE 1572

Query: 122  MQKAEEK-EVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEW 180
            +Q+ E+  EV +  L+  ++T S+SH   DS++    T    +E +  S +   S +  +
Sbjct: 1573 LQEKEKVIEVLQAKLDARSLTPSSSHALSDSHRSPSSTSFLSDELEACSDMDIVSEYTHY 1632

Query: 181  ED 182
            E+
Sbjct: 1633 EE 1634



 Score = 39.7 bits (91), Expect = 0.013
 Identities = 38/121 (31%), Positives = 56/121 (46%), Gaps = 7/121 (5%)

Query: 473  LEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQ---NPPCPRLSRELLD 529
            L    + + L     E+  +G +   R + K   +  K  E+DQ    P   RLSREL +
Sbjct: 1517 LRSNDIDYYLGQSFREQLAQGSQLTERLTSKLSTKDHKS-EKDQAGLEPLALRLSRELQE 1575

Query: 530  -EKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVE 588
             EK  EVLQ  LD    TPS    L+DS +   S  ++ ++  +    DMD + +Y   E
Sbjct: 1576 KEKVIEVLQAKLDARSLTPSSSHALSDSHRSPSSTSFLSDE--LEACSDMDIVSEYTHYE 1633

Query: 589  E 589
            E
Sbjct: 1634 E 1634



 Score = 37.0 bits (84), Expect = 0.084
 Identities = 31/86 (36%), Positives = 44/86 (51%), Gaps = 6/86 (6%)

Query: 583  KYQEVEEDQ---DPSCPRLSGELLD-EKEPEVLQESLDRCYSTPSGCLELTDSCQPYRSA 638
            K  + E+DQ   +P   RLS EL + EK  EVLQ  LD    TPS    L+DS +   S 
Sbjct: 1551 KDHKSEKDQAGLEPLALRLSRELQEKEKVIEVLQAKLDARSLTPSSSHALSDSHRSPSST 1610

Query: 639  FYILEQQRVGLAVDMDEIEKYQEVEE 664
             ++ ++  +    DMD + +Y   EE
Sbjct: 1611 SFLSDE--LEACSDMDIVSEYTHYEE 1634



 Score = 34.3 bits (77), Expect = 0.55
 Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 4/75 (5%)

Query: 414  KDQEEEEDQG---PPCPRLSRELLEVVEP-EVLQDSLDRCYSTPSSCLEQPDSCQPYGSS 469
            KD + E+DQ    P   RLSREL E  +  EVLQ  LD    TPSS     DS +   S+
Sbjct: 1551 KDHKSEKDQAGLEPLALRLSRELQEKEKVIEVLQAKLDARSLTPSSSHALSDSHRSPSST 1610

Query: 470  FYALEEKHVGFSLDV 484
             +  +E      +D+
Sbjct: 1611 SFLSDELEACSDMDI 1625



 Score = 34.3 bits (77), Expect = 0.55
 Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 4/75 (5%)

Query: 733  KDQEEEEDQG---PPCPRLSRELLEVVEP-EVLQDSLDRCYSTPSSCLEQPDSCQPYGSS 788
            KD + E+DQ    P   RLSREL E  +  EVLQ  LD    TPSS     DS +   S+
Sbjct: 1551 KDHKSEKDQAGLEPLALRLSRELQEKEKVIEVLQAKLDARSLTPSSSHALSDSHRSPSST 1610

Query: 789  FYALEEKHVGFSLDV 803
             +  +E      +D+
Sbjct: 1611 SFLSDELEACSDMDI 1625



 Score = 33.9 bits (76), Expect = 0.72
 Identities = 29/85 (34%), Positives = 42/85 (49%), Gaps = 6/85 (7%)

Query: 265  DQVKKEDHEATGP---RLSRELLD-EKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAF 320
            D   ++D     P   RLSREL + EK  EVLQ  LD    TPS    L+DS +   S  
Sbjct: 1552 DHKSEKDQAGLEPLALRLSRELQEKEKVIEVLQAKLDARSLTPSSSHALSDSHRSPSSTS 1611

Query: 321  YVLEQQRVGLAVNMDEIEKYQEVEE 345
            ++ ++  +    +MD + +Y   EE
Sbjct: 1612 FLSDE--LEACSDMDIVSEYTHYEE 1634



 Score = 30.8 bits (68), Expect = 6.1
 Identities = 26/114 (22%), Positives = 55/114 (48%), Gaps = 13/114 (11%)

Query: 10  EEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDK 69
           +EK +   ++ +ELRQ ++ V  ++ +L +LR+ L       +S+   L+A         
Sbjct: 493 DEKFSALEEKEKELRQLRLAVRERDHDLERLRDVLSSNEATMQSMESLLRA--------- 543

Query: 70  SQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQ 123
            +G ++ EQL+  C+  Q L +++  +      E  Q  + +++Q S   R  +
Sbjct: 544 -KGLEV-EQLSTTCQNLQWLKEEMETKFSRWQKE--QESIIQQLQTSLHDRNKE 593



 Score = 30.8 bits (68), Expect = 6.1
 Identities = 26/80 (32%), Positives = 37/80 (46%), Gaps = 3/80 (3%)

Query: 21   EELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLA 80
            E+ R+ +  +    RE +Q  E LRE   +SRS   HLQ L    E  K + Q L E L 
Sbjct: 1909 EDNRRLQAQLSHVSREHSQETESLREALLSSRS---HLQELEKELEHQKVERQQLLEDLR 1965

Query: 81   EGCRLAQHLVQKLSPENDND 100
            E  +   H  ++     +ND
Sbjct: 1966 EKQQEVLHFREERLSLQEND 1985


>gi|239747446 PREDICTED: similar to Neuroblastoma breakpoint family
           member 6-like protein [Homo sapiens]
          Length = 298

 Score = 64.7 bits (156), Expect = 4e-10
 Identities = 43/120 (35%), Positives = 65/120 (54%), Gaps = 8/120 (6%)

Query: 1   MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHL-- 58
           +L  E QF+E +LAE  + A  LR +  L+ AQ  ELT LR+K++EGR       +H+  
Sbjct: 71  VLEEEVQFQERELAELPRSAARLRIHDPLIQAQAEELTHLRQKIQEGRGVCYLFTQHVKN 130

Query: 59  -----QALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDN-DDDEDVQVEVAEK 112
                + LL   +    Q Q   EQ+ +G +L + LV+KL+ EN N   +ED Q  +A +
Sbjct: 131 TVKSFEGLLRNTDIAYYQRQRFCEQMVQGSQLTEILVRKLATENHNGKKNEDRQKPLAPR 190


>gi|239741304 PREDICTED: similar to Neuroblastoma breakpoint family
           member 6-like protein [Homo sapiens]
          Length = 298

 Score = 63.5 bits (153), Expect = 8e-10
 Identities = 43/120 (35%), Positives = 64/120 (53%), Gaps = 8/120 (6%)

Query: 1   MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHL-- 58
           +L  E QF+E +LAE  + A  LR +  L+ AQ  ELT LR+K +EGR       +H+  
Sbjct: 71  VLEEEVQFQERELAELPRSAARLRIHDPLIQAQAEELTHLRQKTQEGRGVCYLFTQHVKN 130

Query: 59  -----QALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDN-DDDEDVQVEVAEK 112
                + LL   +    Q Q   EQ+ +G +L + LV+KL+ EN N   +ED Q  +A +
Sbjct: 131 TVKSFEGLLRNTDIAYYQRQRFCEQMVQGSQLTEILVRKLATENHNGKKNEDRQKPLAPR 190


>gi|239741281 PREDICTED: Neuroblastoma breakpoint family member
           6-like protein [Homo sapiens]
          Length = 322

 Score = 63.5 bits (153), Expect = 8e-10
 Identities = 43/120 (35%), Positives = 64/120 (53%), Gaps = 8/120 (6%)

Query: 1   MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHL-- 58
           +L  E QF+E +LAE  + A  LR +  L+ AQ  ELT LR+K +EGR       +H+  
Sbjct: 71  VLEEEVQFQERELAELPRSAARLRIHDPLIQAQAEELTHLRQKTQEGRGVCYLFTQHVKN 130

Query: 59  -----QALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDN-DDDEDVQVEVAEK 112
                + LL   +    Q Q   EQ+ +G +L + LV+KL+ EN N   +ED Q  +A +
Sbjct: 131 TVKSFEGLLRNTDIAYYQRQRFCEQMVQGSQLTEILVRKLATENHNGKKNEDRQKPLAPR 190


>gi|239752894 PREDICTED: Neuroblastoma breakpoint family member
           6-like protein [Homo sapiens]
          Length = 298

 Score = 60.8 bits (146), Expect = 5e-09
 Identities = 43/120 (35%), Positives = 62/120 (51%), Gaps = 8/120 (6%)

Query: 1   MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHL-- 58
           +L  E QF+E +LAE  + A  LR +  L+ AQ  ELT LR+K +EGR       +H+  
Sbjct: 71  VLEEEVQFQERELAELPRSAARLRIHDPLIQAQAEELTHLRQKTQEGRGVCYLFTQHVKN 130

Query: 59  -----QALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDN-DDDEDVQVEVAEK 112
                + LL        Q Q   EQ+ +G +L + LV+KL  EN N   +ED Q  +A +
Sbjct: 131 TVKSFEGLLRNTGIAYYQRQRFCEQMVQGSQLTEILVRKLVTENHNGKKNEDRQKPLAPR 190


>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
            sapiens]
          Length = 1972

 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 151/772 (19%), Positives = 297/772 (38%), Gaps = 92/772 (11%)

Query: 1    MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQA 60
            +L+  RQ +E +  E   Q  + RQ K      E EL +L +K  +  +    L E LQA
Sbjct: 844  LLQVTRQEEEMQAKEDELQKTKERQQKA-----ENELKELEQKHSQLTEEKNLLQEQLQA 898

Query: 61   LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR 120
                +    ++ ++++ +LA   +  + ++ ++    + ++D   Q++   K        
Sbjct: 899  ----ETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLD 954

Query: 121  EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEW 180
              ++ EE+E     L+   +T               + KI   ED++   L+    + + 
Sbjct: 955  LEEQLEEEEAARQKLQLEKVTA--------------EAKIKKLEDEI---LVMDDQNNKL 997

Query: 181  EDAVHIIPENESD------DEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEM 234
                 ++ E  SD      +EEE+ K     +N  ES   E+      E  S   +  ++
Sbjct: 998  SKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQEL-EKL 1056

Query: 235  LASYKSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDH-EATGPRLSRELLDEKGPEVLQ 293
                +  +S FH   EQ   +   I   +    KKE+  +A   RL  E+  +       
Sbjct: 1057 KRKLEGDASDFH---EQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQK------N 1107

Query: 294  DSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVNMDEIEKYQEVEEDQDPSCPR 353
            ++L +         +L +     R+A    E+Q+  L   ++ ++   E+E+  D +  +
Sbjct: 1108 NALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALK--TELEDTLDSTATQ 1165

Query: 354  LSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLE---EQYLGLALDVD 410
                   E+E  VL+ +L     T S   ++ ++ Q ++ AV  L    EQ+     ++D
Sbjct: 1166 QELRAKREQEVTVLKKALDE--ETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLD 1223

Query: 411  RIKKDQEEEEDQGPPCPRLSRELLEVVEPE------VLQDSLDRCYSTPSSCLEQPDSCQ 464
            + K+  E+E        R+  +  + VE +       +Q+   +C     +  E  D   
Sbjct: 1224 KNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVH 1283

Query: 465  PYGSSFYAL-------EEKHVGFSLDVGEIEKKGKGKK---RRGRRSKKERRRGRKEGEE 514
               +   ++       E K +  + DV  +  + +  +   +   R K       ++ EE
Sbjct: 1284 KLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEE 1343

Query: 515  DQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGL 574
            ++N    +L  E+         + +L+R  ST +  ++L+DS +  +     +E    G 
Sbjct: 1344 ERNSLQDQLDEEM-------EAKQNLERHISTLN--IQLSDSKKKLQDFASTVEALEEGK 1394

Query: 575  AVDMDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQESLDRCYSTPSGCLELTDSCQP 634
                 EIE   +  E++  +  +L      EK    LQ+ LD          +L  + + 
Sbjct: 1395 KRFQKEIENLTQQYEEKAAAYDKL------EKTKNRLQQELDDLVVDLDNQRQLVSNLEK 1448

Query: 635  YRSAF--YILEQQRVG--LAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL 690
             +  F   + E++ +    A + D  E     +E +  S  R   E L+ KE       L
Sbjct: 1449 KQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKE------EL 1502

Query: 691  GRCYSTPSGYLE-LPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQ 741
             R        +E L          V+ LE+    L   ++ +K   EE ED+
Sbjct: 1503 ERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDE 1554


>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
            sapiens]
          Length = 1979

 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 151/772 (19%), Positives = 297/772 (38%), Gaps = 92/772 (11%)

Query: 1    MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQA 60
            +L+  RQ +E +  E   Q  + RQ K      E EL +L +K  +  +    L E LQA
Sbjct: 851  LLQVTRQEEEMQAKEDELQKTKERQQKA-----ENELKELEQKHSQLTEEKNLLQEQLQA 905

Query: 61   LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR 120
                +    ++ ++++ +LA   +  + ++ ++    + ++D   Q++   K        
Sbjct: 906  ----ETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLD 961

Query: 121  EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEW 180
              ++ EE+E     L+   +T               + KI   ED++   L+    + + 
Sbjct: 962  LEEQLEEEEAARQKLQLEKVTA--------------EAKIKKLEDEI---LVMDDQNNKL 1004

Query: 181  EDAVHIIPENESD------DEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEM 234
                 ++ E  SD      +EEE+ K     +N  ES   E+      E  S   +  ++
Sbjct: 1005 SKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQEL-EKL 1063

Query: 235  LASYKSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDH-EATGPRLSRELLDEKGPEVLQ 293
                +  +S FH   EQ   +   I   +    KKE+  +A   RL  E+  +       
Sbjct: 1064 KRKLEGDASDFH---EQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQK------N 1114

Query: 294  DSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVNMDEIEKYQEVEEDQDPSCPR 353
            ++L +         +L +     R+A    E+Q+  L   ++ ++   E+E+  D +  +
Sbjct: 1115 NALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALK--TELEDTLDSTATQ 1172

Query: 354  LSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLE---EQYLGLALDVD 410
                   E+E  VL+ +L     T S   ++ ++ Q ++ AV  L    EQ+     ++D
Sbjct: 1173 QELRAKREQEVTVLKKALDE--ETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLD 1230

Query: 411  RIKKDQEEEEDQGPPCPRLSRELLEVVEPE------VLQDSLDRCYSTPSSCLEQPDSCQ 464
            + K+  E+E        R+  +  + VE +       +Q+   +C     +  E  D   
Sbjct: 1231 KNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVH 1290

Query: 465  PYGSSFYAL-------EEKHVGFSLDVGEIEKKGKGKK---RRGRRSKKERRRGRKEGEE 514
               +   ++       E K +  + DV  +  + +  +   +   R K       ++ EE
Sbjct: 1291 KLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEE 1350

Query: 515  DQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGL 574
            ++N    +L  E+         + +L+R  ST +  ++L+DS +  +     +E    G 
Sbjct: 1351 ERNSLQDQLDEEM-------EAKQNLERHISTLN--IQLSDSKKKLQDFASTVEALEEGK 1401

Query: 575  AVDMDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQESLDRCYSTPSGCLELTDSCQP 634
                 EIE   +  E++  +  +L      EK    LQ+ LD          +L  + + 
Sbjct: 1402 KRFQKEIENLTQQYEEKAAAYDKL------EKTKNRLQQELDDLVVDLDNQRQLVSNLEK 1455

Query: 635  YRSAF--YILEQQRVG--LAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL 690
             +  F   + E++ +    A + D  E     +E +  S  R   E L+ KE       L
Sbjct: 1456 KQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKE------EL 1509

Query: 691  GRCYSTPSGYLE-LPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQ 741
             R        +E L          V+ LE+    L   ++ +K   EE ED+
Sbjct: 1510 ERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDE 1561


>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
            sapiens]
          Length = 1945

 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 151/772 (19%), Positives = 297/772 (38%), Gaps = 92/772 (11%)

Query: 1    MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQA 60
            +L+  RQ +E +  E   Q  + RQ K      E EL +L +K  +  +    L E LQA
Sbjct: 851  LLQVTRQEEEMQAKEDELQKTKERQQKA-----ENELKELEQKHSQLTEEKNLLQEQLQA 905

Query: 61   LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR 120
                +    ++ ++++ +LA   +  + ++ ++    + ++D   Q++   K        
Sbjct: 906  ----ETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLD 961

Query: 121  EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEW 180
              ++ EE+E     L+   +T               + KI   ED++   L+    + + 
Sbjct: 962  LEEQLEEEEAARQKLQLEKVTA--------------EAKIKKLEDEI---LVMDDQNNKL 1004

Query: 181  EDAVHIIPENESD------DEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEM 234
                 ++ E  SD      +EEE+ K     +N  ES   E+      E  S   +  ++
Sbjct: 1005 SKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQEL-EKL 1063

Query: 235  LASYKSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDH-EATGPRLSRELLDEKGPEVLQ 293
                +  +S FH   EQ   +   I   +    KKE+  +A   RL  E+  +       
Sbjct: 1064 KRKLEGDASDFH---EQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQK------N 1114

Query: 294  DSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVNMDEIEKYQEVEEDQDPSCPR 353
            ++L +         +L +     R+A    E+Q+  L   ++ ++   E+E+  D +  +
Sbjct: 1115 NALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALK--TELEDTLDSTATQ 1172

Query: 354  LSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLE---EQYLGLALDVD 410
                   E+E  VL+ +L     T S   ++ ++ Q ++ AV  L    EQ+     ++D
Sbjct: 1173 QELRAKREQEVTVLKKALDE--ETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLD 1230

Query: 411  RIKKDQEEEEDQGPPCPRLSRELLEVVEPE------VLQDSLDRCYSTPSSCLEQPDSCQ 464
            + K+  E+E        R+  +  + VE +       +Q+   +C     +  E  D   
Sbjct: 1231 KNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVH 1290

Query: 465  PYGSSFYAL-------EEKHVGFSLDVGEIEKKGKGKK---RRGRRSKKERRRGRKEGEE 514
               +   ++       E K +  + DV  +  + +  +   +   R K       ++ EE
Sbjct: 1291 KLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEE 1350

Query: 515  DQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGL 574
            ++N    +L  E+         + +L+R  ST +  ++L+DS +  +     +E    G 
Sbjct: 1351 ERNSLQDQLDEEM-------EAKQNLERHISTLN--IQLSDSKKKLQDFASTVEALEEGK 1401

Query: 575  AVDMDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQESLDRCYSTPSGCLELTDSCQP 634
                 EIE   +  E++  +  +L      EK    LQ+ LD          +L  + + 
Sbjct: 1402 KRFQKEIENLTQQYEEKAAAYDKL------EKTKNRLQQELDDLVVDLDNQRQLVSNLEK 1455

Query: 635  YRSAF--YILEQQRVG--LAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL 690
             +  F   + E++ +    A + D  E     +E +  S  R   E L+ KE       L
Sbjct: 1456 KQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKE------EL 1509

Query: 691  GRCYSTPSGYLE-LPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQ 741
             R        +E L          V+ LE+    L   ++ +K   EE ED+
Sbjct: 1510 ERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDE 1561


>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
            sapiens]
          Length = 1938

 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 151/772 (19%), Positives = 297/772 (38%), Gaps = 92/772 (11%)

Query: 1    MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQA 60
            +L+  RQ +E +  E   Q  + RQ K      E EL +L +K  +  +    L E LQA
Sbjct: 844  LLQVTRQEEEMQAKEDELQKTKERQQKA-----ENELKELEQKHSQLTEEKNLLQEQLQA 898

Query: 61   LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR 120
                +    ++ ++++ +LA   +  + ++ ++    + ++D   Q++   K        
Sbjct: 899  ----ETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLD 954

Query: 121  EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEW 180
              ++ EE+E     L+   +T               + KI   ED++   L+    + + 
Sbjct: 955  LEEQLEEEEAARQKLQLEKVTA--------------EAKIKKLEDEI---LVMDDQNNKL 997

Query: 181  EDAVHIIPENESD------DEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEM 234
                 ++ E  SD      +EEE+ K     +N  ES   E+      E  S   +  ++
Sbjct: 998  SKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQEL-EKL 1056

Query: 235  LASYKSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDH-EATGPRLSRELLDEKGPEVLQ 293
                +  +S FH   EQ   +   I   +    KKE+  +A   RL  E+  +       
Sbjct: 1057 KRKLEGDASDFH---EQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQK------N 1107

Query: 294  DSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVNMDEIEKYQEVEEDQDPSCPR 353
            ++L +         +L +     R+A    E+Q+  L   ++ ++   E+E+  D +  +
Sbjct: 1108 NALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALK--TELEDTLDSTATQ 1165

Query: 354  LSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLE---EQYLGLALDVD 410
                   E+E  VL+ +L     T S   ++ ++ Q ++ AV  L    EQ+     ++D
Sbjct: 1166 QELRAKREQEVTVLKKALDE--ETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLD 1223

Query: 411  RIKKDQEEEEDQGPPCPRLSRELLEVVEPE------VLQDSLDRCYSTPSSCLEQPDSCQ 464
            + K+  E+E        R+  +  + VE +       +Q+   +C     +  E  D   
Sbjct: 1224 KNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVH 1283

Query: 465  PYGSSFYAL-------EEKHVGFSLDVGEIEKKGKGKK---RRGRRSKKERRRGRKEGEE 514
               +   ++       E K +  + DV  +  + +  +   +   R K       ++ EE
Sbjct: 1284 KLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEE 1343

Query: 515  DQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGL 574
            ++N    +L  E+         + +L+R  ST +  ++L+DS +  +     +E    G 
Sbjct: 1344 ERNSLQDQLDEEM-------EAKQNLERHISTLN--IQLSDSKKKLQDFASTVEALEEGK 1394

Query: 575  AVDMDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQESLDRCYSTPSGCLELTDSCQP 634
                 EIE   +  E++  +  +L      EK    LQ+ LD          +L  + + 
Sbjct: 1395 KRFQKEIENLTQQYEEKAAAYDKL------EKTKNRLQQELDDLVVDLDNQRQLVSNLEK 1448

Query: 635  YRSAF--YILEQQRVG--LAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL 690
             +  F   + E++ +    A + D  E     +E +  S  R   E L+ KE       L
Sbjct: 1449 KQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKE------EL 1502

Query: 691  GRCYSTPSGYLE-LPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQ 741
             R        +E L          V+ LE+    L   ++ +K   EE ED+
Sbjct: 1503 ERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDE 1554


>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 828

 Score = 54.7 bits (130), Expect = 4e-07
 Identities = 95/515 (18%), Positives = 197/515 (38%), Gaps = 52/515 (10%)

Query: 15  EQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQD 74
           E  +Q EELR+ +  +  QE ++ +  E+LRE     R   E ++         + + ++
Sbjct: 235 EMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELRE 294

Query: 75  LQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSA---PREMQKAEEKEVP 131
            +++L E  +L +   Q    E    + E+   E  EK+ +       +E Q  E+++  
Sbjct: 295 QEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKM 354

Query: 132 EDSLEECAITCSNSHGPYDSNQPHR-KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPEN 190
            D  E            ++ ++  R K +   E++K+              +    + E 
Sbjct: 355 RDQEERM----------WEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREE 404

Query: 191 ESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYKSYSSTFHSLEE 250
           E    E+EEK      N+ E EE+E  Q+   E    L    +M    +        + +
Sbjct: 405 EETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRD 464

Query: 251 QQVCMAVDIGRHRWDQVKKEDHEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 310
           Q+     +  +  W Q K  + E        ++ D++  + + D  +R +       E  
Sbjct: 465 QEEMWGQE--KKMWRQEKMREQEDQMWEQEEKMRDQE--QKMWDQEERMWEQDERLREKE 520

Query: 311 DSCQPYRSAFYVLEQQRVGLAV------NMDEIEKYQEVEEDQDPSCPRLSRELLDEKEP 364
           +  +  +  +   E+ R             D+ EK +E E  ++        E +  ++ 
Sbjct: 521 ERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQE 580

Query: 365 EVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGP 424
           E +Q+   +         E  +  Q     ++  EE            K  ++EEED+  
Sbjct: 581 EKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE------------KMWEQEEEDK-- 626

Query: 425 PCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 484
                 +E +   + E +Q+  ++ +       EQ +  +         EEK  G    +
Sbjct: 627 ---MQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQ-------EEKMQGQEEKM 676

Query: 485 GEIEKKGKGKKRRGRRSKKERRRGRKE---GEEDQ 516
            E E+K +G++ +  R ++E+ RG++E   G+E++
Sbjct: 677 REQEEKMQGQEEK-MREQEEKMRGQEEKMWGQEEK 710


>gi|21735548 centrosomal protein 2 [Homo sapiens]
          Length = 2442

 Score = 54.3 bits (129), Expect = 5e-07
 Identities = 87/396 (21%), Positives = 158/396 (39%), Gaps = 50/396 (12%)

Query: 2    LRNERQFKEEKLAE----QLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEH 57
            L  +RQ  +E+  E       Q   L   K+++  +E+E+   +E + E ++    L + 
Sbjct: 1699 LTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQELKDQLEQQ 1758

Query: 58   LQAL----------LTPDEPD-KSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQ 106
            LQ L          L+  E +     Q LQE   +G    Q L  +L          D +
Sbjct: 1759 LQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQE 1818

Query: 107  VEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDK 166
            +E  ++ Q+ +  +E +  E+ +  + +LE+  +T    HG     Q H++     EE+ 
Sbjct: 1819 LEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGEL---QDHKEQARRLEEE- 1874

Query: 167  VDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKG--PVSPRNLQESEEEEVP----QES 220
                L      V+   A+  +  +   +  E+EK    +  +  ++++E EV     Q+S
Sbjct: 1875 ----LAVEGRRVQ---ALEEVLGDLRAESREQEKALLALQQQCAEQAQEHEVETRALQDS 1927

Query: 221  WDEGYSTLSIPPEMLASYKSYSSTFHSLEE----QQVCMAVDIGRHRWDQVKKEDHEATG 276
            W +  + L    + L + ++ S +    EE    +   +   +G+       KE H    
Sbjct: 1928 WLQAQAVLKERDQELEALRAESQSSRHQEEAARARAEALQEALGKAHAALQGKEQHLLEQ 1987

Query: 277  PRLSRELLDEKGPEVLQDSLDRCYSTPSGCL--------ELTDSCQPYRSAFYVLEQQRV 328
              LSR L  E     LQ SLD C +              E+ D    Y+     L+Q   
Sbjct: 1988 AELSRSL--EASTATLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQEDVQQLQQ--- 2042

Query: 329  GLAVNMDEIEKYQEVEEDQDPS-CPRLSRELLDEKE 363
             LA   +E+   QE E+  + S   R+   ++ EK+
Sbjct: 2043 ALAQRDEELRHQQEREQLLEKSLAQRVQENMIQEKQ 2078



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 37/125 (29%), Positives = 62/125 (49%), Gaps = 14/125 (11%)

Query: 10   EEKLAEQLKQAEELRQYKVLVHAQERELT-----QLREKLREGRDASRSLNEHLQALLTP 64
            +++LA+  +Q E LRQ   +   +E+E T     QL+E  RE ++A+R   + L AL   
Sbjct: 938  QKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLAALQEE 997

Query: 65   DEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQK 124
                     DLQ+Q+ +   L   LV +      +D    V+ EV EK++++     +QK
Sbjct: 998  SSSLLQDKMDLQKQVED---LKSQLVAQ------DDSQRLVEQEVQEKLRETQEYNRIQK 1048

Query: 125  AEEKE 129
              E+E
Sbjct: 1049 ELERE 1053



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 127/623 (20%), Positives = 237/623 (38%), Gaps = 106/623 (17%)

Query: 3    RNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHL---- 58
            + ER+  +        Q E L+   V   AQ      L E LR  R A +  NE +    
Sbjct: 1340 QGERELLQAAKENLTAQVEHLQAAVVEARAQASAAGILEEDLRTARSALKLKNEEVESER 1399

Query: 59   ---QALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQK 115
               QAL    E   +QG+ LQE LA    L Q L ++         +E+V+  +  ++Q+
Sbjct: 1400 ERAQALQEQGELKVAQGKALQENLA---LLTQTLAER---------EEEVET-LRGQIQE 1446

Query: 116  SSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSS 175
                REMQKA        +LE  ++               R  ++  +++++        
Sbjct: 1447 LEKQREMQKA--------ALELLSLDLKK-----------RNQEVDLQQEQIQ------- 1480

Query: 176  SHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEE-EVPQESWDEGYSTLSIPPEM 234
               E E    ++       +E E+K  V    ++E E++ E  +   +     L    +M
Sbjct: 1481 ---ELEKCRSVLEHLPMAVQEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQM 1537

Query: 235  LASYKSYSSTFHSLEEQQVCMAVDI--GRHRWDQVKKEDHEATGPRLSREL--------L 284
            + S +              C+A+++    H+ +  +K   E  G R ++ +        L
Sbjct: 1538 IESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKLIKELEGQRETQRVALTHLTLDL 1597

Query: 285  DEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVNMDEIEKYQEVE 344
            +E+  E LQ    + +   S    L             L+++   +    ++IE+ Q  +
Sbjct: 1598 EERSQE-LQAQSSQIHDLESHSTVLARE----------LQERDQEVKSQREQIEELQRQK 1646

Query: 345  EDQDPSCPRLSRELLDEKEP-EVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYL 403
            E       R  +EL+ +KE  +VL+D   R         +   L +       SL E+  
Sbjct: 1647 EHLTQDLERRDQELMLQKERIQVLEDQRTR---------QTKILEEDLEQIKLSLRER-- 1695

Query: 404  GLALDVDRIKKDQEEEEDQGP-PCPRLSRELLEVV------EPEVLQDSLDRCYSTPSSC 456
            G  L   R    +  EE +GP    R S E ++++      E E  Q+ +          
Sbjct: 1696 GRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQELKDQL 1755

Query: 457  LEQPDSC-QPYGSSFYAL---EEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEG 512
             +Q     +  G +   L   E++ V     + E  ++G+ K++  +    E +R   + 
Sbjct: 1756 EQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQR 1815

Query: 513  EED-----QNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYIL 567
            +++     Q     +   E + EK  + LQ +L++ + T     E     Q ++     L
Sbjct: 1816 DQELEALQQEQQQAQGQEERVKEKA-DALQGALEQAHMT---LKERHGELQDHKEQARRL 1871

Query: 568  EQQRVGLAVDMDEIEKYQEVEED 590
            E++   LAV+   ++  +EV  D
Sbjct: 1872 EEE---LAVEGRRVQALEEVLGD 1891



 Score = 31.2 bits (69), Expect = 4.6
 Identities = 37/133 (27%), Positives = 57/133 (42%), Gaps = 31/133 (23%)

Query: 3   RNERQFKEEKLAEQLKQAEE-----LRQYKVLVHAQERELTQLREKLREGRDASRSLNEH 57
           R++ + + +  A QL QAE+     L Q K    A E+E+ QLREK  + R      + H
Sbjct: 819 RSQAEQERDAAARQLAQAEQEGKTALEQQKA---AHEKEVNQLREKWEKER------SWH 869

Query: 58  LQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVE-VAEKVQKS 116
            Q L    E  + +  +L+ +L E                   + E +Q +   E+ Q  
Sbjct: 870 QQELAKALESLEREKMELEMRLKE----------------QQTEMEAIQAQREEERTQAE 913

Query: 117 SAPREMQKAEEKE 129
           SA  +MQ   EKE
Sbjct: 914 SALCQMQLETEKE 926



 Score = 30.8 bits (68), Expect = 6.1
 Identities = 86/444 (19%), Positives = 161/444 (36%), Gaps = 67/444 (15%)

Query: 10   EEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDK 69
            ++KL ++L+   E ++   L H    +L +  ++L+        L  H   L    +   
Sbjct: 1572 QQKLIKELEGQRETQRV-ALTHLT-LDLEERSQELQAQSSQIHDLESHSTVLARELQERD 1629

Query: 70   SQGQDLQEQLAEGCRLAQHLVQKLSPEND-----------------------NDDDEDVQ 106
             + +  +EQ+ E  R  +HL Q L   +                         +D E ++
Sbjct: 1630 QEVKSQREQIEELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRTRQTKILEEDLEQIK 1689

Query: 107  VEVAEKVQKSSAPREM--QKAEEKEVP----EDSLEECAITCSNSHGPYDSNQPHRKTKI 160
            + + E+ ++ +  R++  ++AEE + P      SLE   +   +     +  Q H   ++
Sbjct: 1690 LSLRERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIH-EL 1748

Query: 161  TFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEE-----EE 215
               +D+++  L G    V          E      + E++  V  + LQE+ E     E+
Sbjct: 1749 QELKDQLEQQLQGLHRKV---------GETSLLLSQREQEIVVLQQQLQEAREQGELKEQ 1799

Query: 216  VPQESWDEGYSTLSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIGRHRWDQV-------- 267
              Q   DE    L+   + L + +         +E++V    D  +   +Q         
Sbjct: 1800 SLQSQLDEAQRALAQRDQELEALQQEQQQAQG-QEERVKEKADALQGALEQAHMTLKERH 1858

Query: 268  -KKEDHEATGPRLSRELLDEKG-----PEVLQDSLDRCYSTPSGCLELTDSC--QPYRSA 319
             + +DH+    RL  EL  E        EVL D            L L   C  Q     
Sbjct: 1859 GELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKALLALQQQCAEQAQEHE 1918

Query: 320  FYVLEQQRVGLAVNMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRCYSTPS 379
                  Q   L       E+ QE+E  +  S     +E       E LQ++LG+ ++   
Sbjct: 1919 VETRALQDSWLQAQAVLKERDQELEALRAESQSSRHQEEAARARAEALQEALGKAHAALQ 1978

Query: 380  G----YLELPDLGQPYSSAVYSLE 399
            G     LE  +L +   ++  +L+
Sbjct: 1979 GKEQHLLEQAELSRSLEASTATLQ 2002


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 188/939 (20%), Positives = 348/939 (37%), Gaps = 148/939 (15%)

Query: 1    MLRNERQFKEEKLAE-QLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQ 59
            +LR ER+ +  +  E Q ++ +EL+Q +  +  +ERE  +L+E+ R+ R+      E  Q
Sbjct: 1003 LLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQ 1062

Query: 60   ALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKL--SPENDNDDDEDVQVEVAEKVQKSS 117
              L  +E +  + Q+L+ Q  +   L Q   Q L   PE     + + Q    E++Q+  
Sbjct: 1063 --LLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEE 1120

Query: 118  AP---REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGS 174
                  E +K   +E+     EE  +         +  +  R+ ++   + + +  L   
Sbjct: 1121 EQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELE-RQYREEEELQQE 1179

Query: 175  SSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWD------------ 222
               +  E+      E E    EEEE      R  +  +E++     W             
Sbjct: 1180 EEQLLREEQEKRRQERERQYREEEEL-QRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDN 1238

Query: 223  -------EGYSTLSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDHEAT 275
                   E      +    L   +S     H L EQQ     +  R RW Q  ++ H   
Sbjct: 1239 KVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQE-RDREQERRRWQQ--RDRHFPE 1295

Query: 276  GPRLSRE------------------LLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYR 317
              +L RE                  L +E+  +  +   DR +      L+  +  QP R
Sbjct: 1296 EEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREE-QPLR 1354

Query: 318  ------------------SAFYVLEQQRVGLAVNMDEIEKYQEVEEDQDPSCPRLSRELL 359
                                 ++ E+QR    +   E E+ + ++E+Q   C    ++L 
Sbjct: 1355 RQERDRKFREEELRHQEQGRKFLEEEQR----LRRQERER-KFLKEEQQLRCQEREQQLR 1409

Query: 360  DEKEPEVLQD--SLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQE 417
             +++ +  ++   L R         E   + +      +  EEQ     L  +R +K +E
Sbjct: 1410 QDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQ----QLRQERHRKFRE 1465

Query: 418  EE------EDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFY 471
            EE      E+Q        R+ LE  E ++ +   DR +       ++P+          
Sbjct: 1466 EEQLLQEREEQQLHRQERDRKFLE-EEQQLRRQERDRKFREQELRSQEPERKFLEEEQQL 1524

Query: 472  ALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKK--ERRRGRKEGEEDQNPPCPRLSRELLD 529
              +++   F  +  ++ ++ +G++RR  R +K  E  + R+E EE Q     R  +  L+
Sbjct: 1525 HRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLE 1584

Query: 530  E----------------------KGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYIL 567
            E                      +G + L+   DR +      L+  +  Q +R      
Sbjct: 1585 EQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQ----- 1639

Query: 568  EQQRVGLAVD--MDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQESLDRCYSTPSGC 625
            E+ R  L  +  +   E+ Q++  D+D         L + +E ++ ++  DR +      
Sbjct: 1640 ERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQ 1699

Query: 626  LELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKE--P 683
            L   +  + +      L +Q +      +E +  QE E++Q     R  R++L+E++  P
Sbjct: 1700 LRRQERERKFLQEEQQLRRQELERKF-REEEQLRQETEQEQLRRQERY-RKILEEEQLRP 1757

Query: 684  EVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKD----QEEEE 739
            E  +  L R       + E   L Q         EEQ L       + +++    QE EE
Sbjct: 1758 EREEQQLRR-QERDRKFREEEQLRQ-------EREEQQLRSQESDRKFREEEQLRQEREE 1809

Query: 740  DQGPPCP-----RLSRELLEVVEPEV-LQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALE 793
             Q  P       R   E L++ E E  L+   DR Y        Q  S +     +   E
Sbjct: 1810 QQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEE 1869

Query: 794  EKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGE 832
            +K           E++ K ++   RR +KE +R R+ GE
Sbjct: 1870 QKR--------RQERERKLREEHIRRQQKEEQRHRQVGE 1900



 Score = 47.0 bits (110), Expect = 8e-05
 Identities = 115/538 (21%), Positives = 204/538 (37%), Gaps = 69/538 (12%)

Query: 2    LRNERQFKEEKLAEQLKQAEE-LRQYKVLVHAQER--------ELTQLREKLREGRDASR 52
            L  E Q +  + A+QL++ E+ L++ +    +QE+        +L + R++ R    A  
Sbjct: 834  LEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKP 893

Query: 53   SLNEHL---QALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEV 109
            +L E L   Q LL  +E      ++LQ +  E  R  +   Q    E    ++E +  E 
Sbjct: 894  ALQEQLRKEQQLLQEEE------EELQREEREKRRRQEQERQYREEEQLQQEEEQLLREE 947

Query: 110  AEKVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEED--KV 167
             EK ++    R+ +K ++ +  E+ L            P    +  R+ K   EE+  + 
Sbjct: 948  REKRRRQERERQYRKDKKLQQKEEQLL--------GEEPEKRRRQEREKKYREEEELQQE 999

Query: 168  DSTLIGSSSHV----EWEDAVHIIPENESDDE----EEEEKGPVSPRNLQESEEEEVPQE 219
            +  L+          EWE       E + ++E    EE EK  +  R  Q  EEEE+ QE
Sbjct: 1000 EEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQE 1059

Query: 220  SWD---EGYSTLSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDHEATG 276
                  E   T     E+   Y+         EE+Q+       R R ++ ++   E   
Sbjct: 1060 EEQLLGEERETRR-RQELERQYRKEEEL--QQEEEQLLREEPEKRRRQERERQCREEEEL 1116

Query: 277  PRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVNMDE 336
             +   +LL E+  +  +  L+R Y                      ++Q+   L     E
Sbjct: 1117 QQEEEQLLREEREKRRRQELERQYREEEE-----------------VQQEEEQLLREEPE 1159

Query: 337  IEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVY 396
              + QE+E        R   EL  E+E  + ++   R       Y E  +L +      Y
Sbjct: 1160 KRRRQELERQY-----REEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRY 1214

Query: 397  SLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSC 456
              E+Q   L    +  K++     D    C     E    +E   L+D   +        
Sbjct: 1215 RDEDQRSDLKWQWEPEKENAVR--DNKVYCKGRENEQFRQLEDSQLRDRQSQ-QDLQHLL 1271

Query: 457  LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEE 514
             EQ +  +      +   ++H  F  +     ++ K  KRR R+S++E++  R+E EE
Sbjct: 1272 GEQQERDREQERRRWQQRDRH--FPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREE 1327



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 109/547 (19%), Positives = 208/547 (38%), Gaps = 53/547 (9%)

Query: 3   RNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALL 62
           R ER+ +EE+L  Q  +  E  ++      + REL +LR K RE +   R   E    + 
Sbjct: 183 REERRAEEEQL--QSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQR--RERQDRVF 238

Query: 63  TPDEPDKSQGQDL-----QEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSS 117
             +E  + + ++      +E+L E     Q  +Q+   +    + ++++ E  E+ Q+  
Sbjct: 239 QEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQ 298

Query: 118 APREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSH 177
             R  Q+   K+  E+   E            +  +  R+ ++  E+++     +     
Sbjct: 299 RLRREQQLRRKQ--EEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQE 356

Query: 178 VEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLAS 237
            E         E +   E+EEE+     R  Q+   E+  +              + L  
Sbjct: 357 EERR-------EQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRR 409

Query: 238 YKSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDHEATGPRLSRELLDEKGPEVLQDSLD 297
            +          EQQ+    +  RH     +K + E    RL RE  + +     ++  +
Sbjct: 410 EQQLRREQQLRREQQLRREQEEERHE----QKHEQERREQRLKREQEERRDWLKREEETE 465

Query: 298 RCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVNMDEIEKYQEVEEDQDPSCPRLSRE 357
           R            D  +  R  +  LE++         E +  +E EE       R  + 
Sbjct: 466 RHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEE-------RREQR 518

Query: 358 LLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQE 417
           L  ++E E LQ  L       S      +  +     +   EE+ L       R+K++QE
Sbjct: 519 LKRQEEEERLQQRLR------SEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQE 572

Query: 418 EEEDQ------GPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFY 471
           E  DQ           RL RE  E +E  + ++ ++R        LEQ +  +       
Sbjct: 573 ERRDQLLKREEERRQQRLKREQEERLEQRLKREEVER--------LEQEERREQRLKREE 624

Query: 472 ALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEK 531
             EE+       + + E++ + ++++ RR ++ERR  R + EE++     RL RE  +E+
Sbjct: 625 PEEERRQ----QLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEER 680

Query: 532 GPEVLQD 538
             + L +
Sbjct: 681 REQELAE 687



 Score = 40.0 bits (92), Expect = 0.010
 Identities = 48/231 (20%), Positives = 96/231 (41%), Gaps = 36/231 (15%)

Query: 5   ERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQAL--- 61
           E++ ++E+  ++LK+ +E R+ ++L   +ER   +L+ + +E R   R   E ++ L   
Sbjct: 555 EKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKRE-QEERLEQRLKREEVERLEQE 613

Query: 62  ------LTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDND---DDEDVQVEVAEK 112
                 L  +EP++ + Q L +   +  R  Q L ++     +     ++E+ ++E   K
Sbjct: 614 ERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLK 673

Query: 113 VQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLI 172
            +     RE + AEE++  E + E             +S    R++K+     K      
Sbjct: 674 REHEEERREQELAEEEQ--EQARERIKSRIPKWQWQLESEADARQSKVYSRPRK------ 725

Query: 173 GSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDE 223
                           E +   +E+EEK       LQ  EEE   ++  +E
Sbjct: 726 ---------------QEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEE 761



 Score = 39.7 bits (91), Expect = 0.013
 Identities = 39/217 (17%), Positives = 91/217 (41%), Gaps = 5/217 (2%)

Query: 5   ERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTP 64
           ER+ ++E+  +QL++ +E R+ + L   +E E  +L+++LR  +   R   E  + LL  
Sbjct: 495 ERREQQERREQQLRREQEERREQRLKRQEEEE--RLQQRLRSEQQLRREQEERREQLLKR 552

Query: 65  DEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQK 124
           +E +K   Q+ +EQ  +  R  +    +L    +    + ++ E  E++++     E+++
Sbjct: 553 EE-EKRLEQERREQRLK--REQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVER 609

Query: 125 AEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAV 184
            E++E  E  L+              S +   + +     ++ +          E E   
Sbjct: 610 LEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLE 669

Query: 185 HIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESW 221
             +     ++  E+E         +E  +  +P+  W
Sbjct: 670 QRLKREHEEERREQELAEEEQEQARERIKSRIPKWQW 706



 Score = 36.6 bits (83), Expect = 0.11
 Identities = 57/292 (19%), Positives = 112/292 (38%), Gaps = 31/292 (10%)

Query: 2   LRNERQFKEEKLAEQLKQAEELRQYKVLVHAQEREL-TQLREKLREGRDASRSLNEHLQA 60
           LR E+Q + E   +QL++ ++LR+ + L   QE E   Q  E+ R  +   R   E    
Sbjct: 401 LRREQQLRRE---QQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDW 457

Query: 61  LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR 120
           L   +E ++ + +  ++QL       +        E +  + ++ + +   + Q+    +
Sbjct: 458 LKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQ 517

Query: 121 EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKI--TFEEDKVDSTLIGSSSHV 178
            +++ EE+E  +  L         S       Q  R+ ++    EE +++          
Sbjct: 518 RLKRQEEEERLQQRL--------RSEQQLRREQEERREQLLKREEEKRLEQERREQRLKR 569

Query: 179 EWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTLSIPPEML 235
           E E+    + + E +  ++  K     R    L+  E E + QE   E       P E  
Sbjct: 570 EQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEE- 628

Query: 236 ASYKSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDHEATGPRLSRELLDEK 287
                          QQ+  + +    R  Q+++E  E    RL RE  +E+
Sbjct: 629 -------------RRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEER 667



 Score = 34.7 bits (78), Expect = 0.42
 Identities = 57/270 (21%), Positives = 104/270 (38%), Gaps = 29/270 (10%)

Query: 40  LREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDN 99
           L +  R+  D  R      Q    P +  + + Q+ + +LAEG   ++   ++L   +  
Sbjct: 109 LLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQ-ERLEQRDRQ 167

Query: 100 DDDEDV---QVEVAEKVQKSSAPREMQKA---EEKEVP-EDSLEECAITCSNSHGPYDSN 152
             DE++   + E  E+ ++ +   ++Q     E +E P E+ L    +      G  +  
Sbjct: 168 RRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQ 227

Query: 153 QPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESE 212
           Q  R+      +D+V           EW     ++ + E   +EEE   P   R LQE E
Sbjct: 228 QQRRE-----RQDRV----FQEEEEKEWRKRETVLRKEEEKLQEEE---PQRQRELQEEE 275

Query: 213 E-------EEVPQESWDEGYSTLSIPPEMLASYKSYSSTFHSLEE--QQVCMAVDIGRHR 263
           E       +E+ +E  +E      +  E     K         EE  +Q          R
Sbjct: 276 EQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERR 335

Query: 264 WDQVKKEDHEATGPRLSRELLDEKGPEVLQ 293
             Q+++E  E    +L RE  +E+  + L+
Sbjct: 336 EQQLRREQEERREQQLRREQEEERREQQLR 365



 Score = 33.1 bits (74), Expect = 1.2
 Identities = 32/135 (23%), Positives = 61/135 (45%), Gaps = 12/135 (8%)

Query: 3   RNERQFKEEKLAEQL---KQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQ 59
           R +R+  EE+  +QL   ++ EE RQ ++    QER   +L+ +  E R   R   EH  
Sbjct: 619 RLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREH-- 676

Query: 60  ALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAP 119
                 E ++ + +  +E+  +     +  + K   + +++ D   Q +V  + +K    
Sbjct: 677 ------EEERREQELAEEEQEQARERIKSRIPKWQWQLESEADAR-QSKVYSRPRKQEGQ 729

Query: 120 REMQKAEEKEVPEDS 134
           R  Q+ EEK    +S
Sbjct: 730 RRRQEQEEKRRRRES 744



 Score = 30.4 bits (67), Expect = 7.9
 Identities = 39/148 (26%), Positives = 63/148 (42%), Gaps = 22/148 (14%)

Query: 718 EEQYLGLALDVDRIKKDQEEEEDQ------GPPCPRLSRELLEVVEPEVLQDSLDRCYST 771
           EE+ L       R+K++QEE  DQ           RL RE  E +E  + ++ ++R    
Sbjct: 554 EEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVER---- 609

Query: 772 PSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEG 831
               LEQ +  +         EE+     L   E E++ + + RR ++ ++E+R  R+E 
Sbjct: 610 ----LEQEERREQRLKREEPEEERRQQL-LKSEEQEERRQQQLRREQQERREQRLKREEE 664

Query: 832 EEDQNPPCPRLNSMLMEVEEPEVLQDSL 859
           EE       RL   L    E E  +  L
Sbjct: 665 EE-------RLEQRLKREHEEERREQEL 685


>gi|48255889 protein kinase C substrate 80K-H isoform 1 [Homo
           sapiens]
          Length = 528

 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 74/334 (22%), Positives = 131/334 (39%), Gaps = 26/334 (7%)

Query: 5   ERQFKEEKLAEQLKQA--EELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALL 62
           E+  KE +  +Q+ +   E  R  K+L+   ++   + ++KL E +   +SL + ++ L 
Sbjct: 118 EKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEMLR 177

Query: 63  T-------PDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQK 115
           T       P+   K Q Q L E+     +  Q          + DDD D  V V E    
Sbjct: 178 TVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTH 237

Query: 116 SSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSS 175
                +   A  +   +  L     T + S   YD      + K   E    D     + 
Sbjct: 238 PELDTDGDGALSEAEAQALLSGDTQTDATSF--YDRVWAAIRDKYRSEALPTDLPAPSAP 295

Query: 176 SHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEML 235
              E ++    +P + +++EEEEE+        +E EEE    E  +E    LS PP+  
Sbjct: 296 DLTEPKEEQPPVPSSPTEEEEEEEEE--EEEEAEEEEEE----EDSEEAPPPLS-PPQPA 348

Query: 236 ASYKSYSSTFHSLEEQQVCMAVDIGRHRWDQVKK--EDHEATGPRLSRELLDEKGPEVLQ 293
           +  +      +  + Q    A    R+++++ ++  +D E +   L +E+  + GP    
Sbjct: 349 SPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEISFDFGP---N 405

Query: 294 DSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQR 327
                 YS    C ELT +   YR   + L  Q+
Sbjct: 406 GEFAYLYSQ---CYELTTNEYVYRLCPFKLVSQK 436


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.132    0.378 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,281,167
Number of Sequences: 37866
Number of extensions: 2313065
Number of successful extensions: 17186
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 88
Number of HSP's successfully gapped in prelim test: 492
Number of HSP's that attempted gapping in prelim test: 12160
Number of HSP's gapped (non-prelim): 3178
length of query: 921
length of database: 18,247,518
effective HSP length: 112
effective length of query: 809
effective length of database: 14,006,526
effective search space: 11331279534
effective search space used: 11331279534
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.