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Search of human proteins with 7656950
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7656950 voltage-dependent calcium channel gamma-5 subunit
isoform b [Homo sapiens]
(296 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7656950 voltage-dependent calcium channel gamma-5 subunit iso... 607 e-174
gi|22027551 voltage-dependent calcium channel gamma-5 subunit is... 380 e-105
gi|21361975 voltage-dependent calcium channel gamma-7 subunit [H... 283 2e-76
gi|7656948 voltage-dependent calcium channel gamma-4 subunit [Ho... 116 3e-26
gi|24586686 voltage-dependent calcium channel gamma-8 subunit [H... 110 1e-24
gi|5729756 voltage-dependent calcium channel gamma-3 subunit [Ho... 109 3e-24
gi|5174405 voltage-dependent calcium channel gamma-2 subunit [Ho... 108 7e-24
gi|239756473 PREDICTED: transmembrane protein 114 [Homo sapiens] 49 5e-06
gi|226437592 transmembrane protein 114 [Homo sapiens] 49 5e-06
gi|239752599 PREDICTED: transmembrane protein 114, partial [Homo... 47 2e-05
gi|4502539 voltage-dependent calcium channel gamma-1 subunit [Ho... 47 2e-05
gi|183979973 claudin 19 isoform a [Homo sapiens] 42 6e-04
gi|183979975 claudin 19 isoform b [Homo sapiens] 42 6e-04
gi|22748835 transmembrane protein 178 [Homo sapiens] 39 0.007
gi|153792186 claudin 7 [Homo sapiens] 37 0.016
gi|5921465 claudin 10 isoform b [Homo sapiens] 37 0.016
gi|10863887 claudin 1 [Homo sapiens] 36 0.035
gi|33598916 claudin 10 isoform a [Homo sapiens] 34 0.13
gi|4502877 claudin 4 [Homo sapiens] 33 0.23
gi|239916002 lens intrinsic membrane protein 2, 19kDa isoform 2 ... 33 0.30
gi|116292168 KRAB A domain containing 1 [Homo sapiens] 33 0.30
gi|93588657 claudin domain containing 1 protein isoform d [Homo ... 32 0.51
gi|93588650 claudin domain containing 1 protein isoform a [Homo ... 32 0.51
gi|93588620 claudin domain containing 1 protein isoform b [Homo ... 32 0.51
gi|93588614 claudin domain containing 1 protein isoform a [Homo ... 32 0.51
gi|93588624 claudin domain containing 1 protein isoform a [Homo ... 32 0.51
gi|11096340 claudin domain containing 1 protein isoform a [Homo ... 32 0.51
gi|231569235 claudin 10 isoform a_i1 [Homo sapiens] 32 0.67
gi|4505907 peripheral myelin protein 22 [Homo sapiens] 32 0.87
gi|24430165 peripheral myelin protein 22 [Homo sapiens] 32 0.87
>gi|7656950 voltage-dependent calcium channel gamma-5 subunit
isoform b [Homo sapiens]
Length = 296
Score = 607 bits (1566), Expect = e-174
Identities = 296/296 (100%), Positives = 296/296 (100%)
Query: 1 MSACGRKALTLLSSVFAVCGLGLLGIAVSTDYWLYLEEGVIVPQNQSTEIKMSLHSGLWR 60
MSACGRKALTLLSSVFAVCGLGLLGIAVSTDYWLYLEEGVIVPQNQSTEIKMSLHSGLWR
Sbjct: 1 MSACGRKALTLLSSVFAVCGLGLLGIAVSTDYWLYLEEGVIVPQNQSTEIKMSLHSGLWR 60
Query: 61 VCFLAGEERGRCFTIEYVMPMNTQLTSESTVNVLKMIRSATPFPLVSLFFMFIGFILNNI 120
VCFLAGEERGRCFTIEYVMPMNTQLTSESTVNVLKMIRSATPFPLVSLFFMFIGFILNNI
Sbjct: 61 VCFLAGEERGRCFTIEYVMPMNTQLTSESTVNVLKMIRSATPFPLVSLFFMFIGFILNNI 120
Query: 121 GHIRPHRTILAFVSGIFFILSGLSLVVGLVLYISSINDEMLNRTKDAETYFNYKYGWSFA 180
GHIRPHRTILAFVSGIFFILSGLSLVVGLVLYISSINDEMLNRTKDAETYFNYKYGWSFA
Sbjct: 121 GHIRPHRTILAFVSGIFFILSGLSLVVGLVLYISSINDEMLNRTKDAETYFNYKYGWSFA 180
Query: 181 FAAISFLLTEVKPVTLSMDRLGLGTAPLSRGEWGWGRRDIPQPFWTPDHPLYFPSSSQNV 240
FAAISFLLTEVKPVTLSMDRLGLGTAPLSRGEWGWGRRDIPQPFWTPDHPLYFPSSSQNV
Sbjct: 181 FAAISFLLTEVKPVTLSMDRLGLGTAPLSRGEWGWGRRDIPQPFWTPDHPLYFPSSSQNV 240
Query: 241 SLSYLSGSPPARMSPGPCSCPHVHFPPHSSCVLCRPQPREMRQAPAASPSSAVFSL 296
SLSYLSGSPPARMSPGPCSCPHVHFPPHSSCVLCRPQPREMRQAPAASPSSAVFSL
Sbjct: 241 SLSYLSGSPPARMSPGPCSCPHVHFPPHSSCVLCRPQPREMRQAPAASPSSAVFSL 296
>gi|22027551 voltage-dependent calcium channel gamma-5 subunit
isoform a [Homo sapiens]
Length = 275
Score = 380 bits (975), Expect = e-105
Identities = 195/203 (96%), Positives = 195/203 (96%), Gaps = 3/203 (1%)
Query: 1 MSACGRKALTLLSSVFAVCGLGLLGIAVSTDYWLYLEEGVIVPQNQSTEIKMSLHSGLWR 60
MSACGRKALTLLSSVFAVCGLGLLGIAVSTDYWLYLEEGVIVPQNQSTEIKMSLHSGLWR
Sbjct: 1 MSACGRKALTLLSSVFAVCGLGLLGIAVSTDYWLYLEEGVIVPQNQSTEIKMSLHSGLWR 60
Query: 61 VCFLAGEERGRCFTIEYVMPMNTQLTSESTVNVLKMIRSATPFPLVSLFFMFIGFILNNI 120
VCFLAGEERGRCFTIEYVMPMNTQLTSESTVNVLKMIRSATPFPLVSLFFMFIGFILNNI
Sbjct: 61 VCFLAGEERGRCFTIEYVMPMNTQLTSESTVNVLKMIRSATPFPLVSLFFMFIGFILNNI 120
Query: 121 GHIRPHRTILAFVSGIFFILSGLSLVVGLVLYISSINDEMLNRTKDAETYFNYKYGWSFA 180
GHIRPHRTILAFVSGIFFILSGLSLVVGLVLYISSINDEMLNRTKDAETYFNYKYGWSFA
Sbjct: 121 GHIRPHRTILAFVSGIFFILSGLSLVVGLVLYISSINDEMLNRTKDAETYFNYKYGWSFA 180
Query: 181 FAAISFLLTE---VKPVTLSMDR 200
FAAISFLLTE V V L M R
Sbjct: 181 FAAISFLLTESAGVMSVYLFMKR 203
>gi|21361975 voltage-dependent calcium channel gamma-7 subunit [Homo
sapiens]
Length = 275
Score = 283 bits (723), Expect = 2e-76
Identities = 133/190 (70%), Positives = 159/190 (83%)
Query: 1 MSACGRKALTLLSSVFAVCGLGLLGIAVSTDYWLYLEEGVIVPQNQSTEIKMSLHSGLWR 60
MS C +ALTLLSSVF CGL L+GIAVSTDYWLY+EEG ++PQNQ+TE+KM+LH+GLWR
Sbjct: 1 MSHCSSRALTLLSSVFGACGLLLVGIAVSTDYWLYMEEGTVLPQNQTTEVKMALHAGLWR 60
Query: 61 VCFLAGEERGRCFTIEYVMPMNTQLTSESTVNVLKMIRSATPFPLVSLFFMFIGFILNNI 120
VCF AG E+GRC EY + L +E+T N+LK +R+ATPFP+VSLF +F F+++NI
Sbjct: 61 VCFFAGREKGRCVASEYFLEPEINLVTENTENILKTVRTATPFPMVSLFLVFTAFVISNI 120
Query: 121 GHIRPHRTILAFVSGIFFILSGLSLVVGLVLYISSINDEMLNRTKDAETYFNYKYGWSFA 180
GHIRP RTILAFVSGIFFILSGLSLVVGLVLYISSINDE++NR +E YF+Y+YGWSFA
Sbjct: 121 GHIRPQRTILAFVSGIFFILSGLSLVVGLVLYISSINDEVMNRPSSSEQYFHYRYGWSFA 180
Query: 181 FAAISFLLTE 190
FAA SFLL E
Sbjct: 181 FAASSFLLKE 190
>gi|7656948 voltage-dependent calcium channel gamma-4 subunit [Homo
sapiens]
Length = 327
Score = 116 bits (290), Expect = 3e-26
Identities = 62/198 (31%), Positives = 106/198 (53%), Gaps = 10/198 (5%)
Query: 1 MSACGRKALTLLSSVFAVCGLGLLGIAVSTDYWLYLEEGVIVPQNQSTEIKMS------- 53
M C R LL++ A L+ IA+ TDYWLY + N + +
Sbjct: 1 MVRCDRGLQMLLTTAGAFAAFSLMAIAIGTDYWLYSSAHICNGTNLTMDDGPPPRRARGD 60
Query: 54 -LHSGLWRVCFLAGEERGRCFTIEYVMPMNTQLTSESTVNVLKMIRSATPFPLVSLFFMF 112
HSGLWRVC + G +G CF I + P + +S+ +L+++R+++ FP++S +
Sbjct: 61 LTHSGLWRVCCIEGIYKGHCFRINH-FPEDNDYDHDSSEYLLRIVRASSVFPILSTILLL 119
Query: 113 IGFILNNIGHIRPHRTILAFVSGIFFILSGLSLVVGLVLYISSINDEMLNRTKDAETYFN 172
+G + G I + + +GI F+ +GLS ++G+++YISS + ++ +D + +
Sbjct: 120 LGGLCIGAGRIYSRKNNIVLSAGILFVAAGLSNIIGIIVYISSNTGDPSDK-RDEDKKNH 178
Query: 173 YKYGWSFAFAAISFLLTE 190
Y YGWSF F A+SF++ E
Sbjct: 179 YNYGWSFYFGALSFIVAE 196
>gi|24586686 voltage-dependent calcium channel gamma-8 subunit [Homo
sapiens]
Length = 425
Score = 110 bits (276), Expect = 1e-24
Identities = 64/206 (31%), Positives = 105/206 (50%), Gaps = 20/206 (9%)
Query: 4 CGRKALTLLSSVFAVCGLGLLGIAVSTDYWLYLEEGVIVPQN------------------ 45
C + LL++V A GL+ IA+STDYWLY + N
Sbjct: 15 CEKGVQVLLTTVGAFAAFGLMTIAISTDYWLYTRALICNTTNLTAGGDDGTPHRGGGGAS 74
Query: 46 QSTEIKMSLHSGLWRVCFLAGEERGRCFTIEYVMPMNTQLTSESTVNVLKMIRSATPFPL 105
+ + HSGLWR+C L G +RG C I + P +T +S +L+++R+++ FP+
Sbjct: 75 EKKDPGGLTHSGLWRICCLEGLKRGVCVKINH-FPEDTDYDHDSAEYLLRVVRASSIFPI 133
Query: 106 VSLFFMFIGFILNNIGHIRPHRTILAFVSGIFFILSGLSLVVGLVLYISSINDEMLNRTK 165
+S + +G + + + + +GI F+ +GLS ++G+++YIS+ N +
Sbjct: 134 LSAILLLLGGVCVAASRVYKSKRNIILGAGILFVAAGLSNIIGVIVYISA-NAGEPGPKR 192
Query: 166 DAETYFNYKYGWSFAFAAISFLLTEV 191
D E +Y YGWSF F +SF+L EV
Sbjct: 193 DEEKKNHYSYGWSFYFGGLSFILAEV 218
>gi|5729756 voltage-dependent calcium channel gamma-3 subunit [Homo
sapiens]
Length = 315
Score = 109 bits (272), Expect = 3e-24
Identities = 64/197 (32%), Positives = 105/197 (53%), Gaps = 12/197 (6%)
Query: 1 MSACGRKALTLLSSVFAVCGLGLLGIAVSTDYWLYLEEGVIVPQNQSTEI------KMSL 54
M C R L+++V A L+ IAV TDYWLY GV ++ S ++
Sbjct: 1 MRMCDRGIQMLITTVGAFAAFSLMTIAVGTDYWLY-SRGVCRTKSTSDNETSRKNEEVMT 59
Query: 55 HSGLWRVCFLAGEERGRCFTIEYVMPMNTQLTSESTVNVLKMIRSATPFPLVSLFFMFIG 114
HSGLWR C L G RG C I++ P + ++ +L+ +R+++ FP++S+ +F G
Sbjct: 60 HSGLWRTCCLEGAFRGVCKKIDH-FPEDADYEQDTAEYLLRAVRASSVFPILSVTLLFFG 118
Query: 115 FILNNIGHIRPHRTILAFVSGIFFILSGLSLVVGLVLYISSINDEMLNRTKDAETYFNYK 174
+ R + +GIFF+ +GLS ++G+++YIS+ + R ++ +Y
Sbjct: 119 GLCVAASEFHRSRHNVILSAGIFFVSAGLSNIIGIIVYISANAGDPGQR----DSKKSYS 174
Query: 175 YGWSFAFAAISFLLTEV 191
YGWSF F A SF++ E+
Sbjct: 175 YGWSFYFGAFSFIIAEI 191
>gi|5174405 voltage-dependent calcium channel gamma-2 subunit [Homo
sapiens]
Length = 323
Score = 108 bits (269), Expect = 7e-24
Identities = 64/197 (32%), Positives = 109/197 (55%), Gaps = 11/197 (5%)
Query: 1 MSACGRKALTLLSSVFAVCGLGLLGIAVSTDYWLYLEEGVI----VPQNQSTEI--KMSL 54
M R LL++V A L+ IAV TDYWLY GV V +N++++ ++
Sbjct: 1 MGLFDRGVQMLLTTVGAFAAFSLMTIAVGTDYWLY-SRGVCKTKSVSENETSKKNEEVMT 59
Query: 55 HSGLWRVCFLAGEERGRCFTIEYVMPMNTQLTSESTVNVLKMIRSATPFPLVSLFFMFIG 114
HSGLWR C L G +G C I++ P + +++ L+ +R+++ FP++S+ +F+G
Sbjct: 60 HSGLWRTCCLEGNFKGLCKQIDH-FPEDADYEADTAEYFLRAVRASSIFPILSVILLFMG 118
Query: 115 FILNNIGHIRPHRTILAFVSGIFFILSGLSLVVGLVLYISSINDEMLNRTKDAETYFNYK 174
+ R + +GIFF+ +GLS ++G+++YIS+ + +K +Y
Sbjct: 119 GLCIAASEFYKTRHNIILSAGIFFVSAGLSNIIGIIVYISA---NAGDPSKSDSKKNSYS 175
Query: 175 YGWSFAFAAISFLLTEV 191
YGWSF F A+SF++ E+
Sbjct: 176 YGWSFYFGALSFIIAEM 192
>gi|239756473 PREDICTED: transmembrane protein 114 [Homo sapiens]
Length = 223
Score = 48.9 bits (115), Expect = 5e-06
Identities = 42/181 (23%), Positives = 76/181 (41%), Gaps = 21/181 (11%)
Query: 23 LLGIAVSTDYWLYLE-----------EGVIVPQNQSTEIKMSLHSGLWRVCFLAGEERGR 71
LL A+ TD+W ++ + ++ N+S +S HSGLWR C +
Sbjct: 22 LLAAAIGTDFWYIIDTERLERTGPGAQDLLGSINRSQPEPLSSHSGLWRTC----RVQSP 77
Query: 72 CFTIEYVMPMNTQLTSESTVNVLKMIRSATPFPLVSLFFMFIGFILNNIGHIRPHRTILA 131
C + + SES+ +L M + +SL M G + + + +L
Sbjct: 78 CTPLMNPFRLENVTVSESSRQLLTMHGTFVILLPLSLILMVFGGMTGFLSFLL-QAYLLL 136
Query: 132 FVSGIFFILSGLSLVVGLVLYI----SSINDEM-LNRTKDAETYFNYKYGWSFAFAAISF 186
++GI F+ + + G+ +YI ++ + + L K + +GWS A ISF
Sbjct: 137 LLTGILFLFGAMVTLAGISVYIAYSAAAFREALCLLEEKALLDQVDISFGWSLALGWISF 196
Query: 187 L 187
+
Sbjct: 197 I 197
>gi|226437592 transmembrane protein 114 [Homo sapiens]
Length = 223
Score = 48.9 bits (115), Expect = 5e-06
Identities = 42/181 (23%), Positives = 76/181 (41%), Gaps = 21/181 (11%)
Query: 23 LLGIAVSTDYWLYLE-----------EGVIVPQNQSTEIKMSLHSGLWRVCFLAGEERGR 71
LL A+ TD+W ++ + ++ N+S +S HSGLWR C +
Sbjct: 22 LLAAAIGTDFWYIIDTERLERTGPGAQDLLGSINRSQPEPLSSHSGLWRTC----RVQSP 77
Query: 72 CFTIEYVMPMNTQLTSESTVNVLKMIRSATPFPLVSLFFMFIGFILNNIGHIRPHRTILA 131
C + + SES+ +L M + +SL M G + + + +L
Sbjct: 78 CTPLMNPFRLENVTVSESSRQLLTMHGTFVILLPLSLILMVFGGMTGFLSFLL-QAYLLL 136
Query: 132 FVSGIFFILSGLSLVVGLVLYI----SSINDEM-LNRTKDAETYFNYKYGWSFAFAAISF 186
++GI F+ + + G+ +YI ++ + + L K + +GWS A ISF
Sbjct: 137 LLTGILFLFGAMVTLAGISVYIAYSAAAFREALCLLEEKALLDQVDISFGWSLALGWISF 196
Query: 187 L 187
+
Sbjct: 197 I 197
>gi|239752599 PREDICTED: transmembrane protein 114, partial [Homo
sapiens]
Length = 217
Score = 47.4 bits (111), Expect = 2e-05
Identities = 41/181 (22%), Positives = 76/181 (41%), Gaps = 21/181 (11%)
Query: 23 LLGIAVSTDYWLYLE-----------EGVIVPQNQSTEIKMSLHSGLWRVCFLAGEERGR 71
LL A+ T++W ++ + ++ N+S +S HSGLWR C +
Sbjct: 16 LLAAAIGTEFWYIIDTERLERTGPGAQDLLGSINRSQPEPLSSHSGLWRTC----RVQSP 71
Query: 72 CFTIEYVMPMNTQLTSESTVNVLKMIRSATPFPLVSLFFMFIGFILNNIGHIRPHRTILA 131
C + + SES+ +L M + +SL M G + + + +L
Sbjct: 72 CTPLMNPFRLENVTVSESSRQLLTMHGTFVILLPLSLILMVFGGMTGFLSFLL-QAYLLL 130
Query: 132 FVSGIFFILSGLSLVVGLVLYI----SSINDEM-LNRTKDAETYFNYKYGWSFAFAAISF 186
++GI F+ + + G+ +YI ++ + + L K + +GWS A ISF
Sbjct: 131 LLTGILFLFGAMVTLAGISVYIAYSAAAFREALCLLEEKALLDQVDISFGWSLALGWISF 190
Query: 187 L 187
+
Sbjct: 191 I 191
>gi|4502539 voltage-dependent calcium channel gamma-1 subunit [Homo
sapiens]
Length = 222
Score = 47.0 bits (110), Expect = 2e-05
Identities = 53/202 (26%), Positives = 89/202 (44%), Gaps = 35/202 (17%)
Query: 7 KALTLLSSVFAV-CGLGLLGIAVSTDYWLYLEEGVIVPQNQSTEIKMSLHSGLWRVCF-- 63
K L + ++F + G+ L AV TD+W L + ++ +T + + H GLWR+C
Sbjct: 5 KMLKVRVTLFCILAGIVLAMTAVVTDHWAVLSPHM---EHHNTTCEAA-HFGLWRICTKR 60
Query: 64 -------------LAGEERGRCFTIEYVMPMNTQLTSESTVNVLKMIRSATPFPLVSLFF 110
L GE+ C + P + E T I SA + SL F
Sbjct: 61 IPMDDSKTCGPITLPGEKN--CSYFRHFNPGESSEIFEFTTQKEYSI-SAAAIAIFSLGF 117
Query: 111 MFIGF--ILNNIGHIRPHRTILAFVSGIFFILSGLSLVVGLVLYISSINDEMLNRTKDAE 168
+ +G +L ++G R + L + +F+ +GL ++V + + S+ R D+E
Sbjct: 118 IILGSLCVLLSLGKKRDY---LLRPASMFYAFAGLCILVSVEVMRQSVK-----RMIDSE 169
Query: 169 --TYFNYKYGWSFAFAAISFLL 188
+ Y Y WSFA A +F+L
Sbjct: 170 DTVWIEYYYSWSFACACAAFIL 191
>gi|183979973 claudin 19 isoform a [Homo sapiens]
Length = 224
Score = 42.0 bits (97), Expect = 6e-04
Identities = 34/177 (19%), Positives = 71/177 (40%), Gaps = 17/177 (9%)
Query: 20 GLGLLGIAVSTDYWLYLEEGVIVPQNQSTEIK-------MSLHSGLWRVCFLAGEERGRC 72
GL LLG ++ W+ + +PQ + + + L+ GLW C + +C
Sbjct: 5 GLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTGQVQC 64
Query: 73 FTIEYVMPMNTQLTSESTVNVLKMIRSATPFPLVSLFFMFIGFILNNIGHIRP-HRTILA 131
+ ++ ++ + S + V+ ++ V++ +G +G P + +A
Sbjct: 65 KLYDSLLALDGHIQSARALMVVAVLLG-----FVAMVLSVVGMKCTRVGDSNPIAKGRVA 119
Query: 132 FVSGIFFILSGLSLVVGLVLYISSINDEMLNRTKDAETYFNYK----YGWSFAFAAI 184
G FIL+GL + + Y + + E N + + + GW+ A A+
Sbjct: 120 IAGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAV 176
>gi|183979975 claudin 19 isoform b [Homo sapiens]
Length = 211
Score = 42.0 bits (97), Expect = 6e-04
Identities = 34/177 (19%), Positives = 71/177 (40%), Gaps = 17/177 (9%)
Query: 20 GLGLLGIAVSTDYWLYLEEGVIVPQNQSTEIK-------MSLHSGLWRVCFLAGEERGRC 72
GL LLG ++ W+ + +PQ + + + L+ GLW C + +C
Sbjct: 5 GLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTGQVQC 64
Query: 73 FTIEYVMPMNTQLTSESTVNVLKMIRSATPFPLVSLFFMFIGFILNNIGHIRP-HRTILA 131
+ ++ ++ + S + V+ ++ V++ +G +G P + +A
Sbjct: 65 KLYDSLLALDGHIQSARALMVVAVLLG-----FVAMVLSVVGMKCTRVGDSNPIAKGRVA 119
Query: 132 FVSGIFFILSGLSLVVGLVLYISSINDEMLNRTKDAETYFNYK----YGWSFAFAAI 184
G FIL+GL + + Y + + E N + + + GW+ A A+
Sbjct: 120 IAGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAV 176
>gi|22748835 transmembrane protein 178 [Homo sapiens]
Length = 297
Score = 38.5 bits (88), Expect = 0.007
Identities = 34/160 (21%), Positives = 69/160 (43%), Gaps = 27/160 (16%)
Query: 55 HSGLWRVCFLAGEERG-----------RCFTIEY---------VMPMN-TQLTSESTVNV 93
+SGLWR C+ G +R RC I+Y +P N T+ + ++
Sbjct: 111 YSGLWRKCYFLGIDRDIDTLILKGIAQRCTAIKYHFSQPIRLRNIPFNLTKTIQQDEWHL 170
Query: 94 LKMIRSATPFPLVSLFFMFIGFILNNIGHIRPHRTILAFVSGIFFILSGLSLVVGLVLYI 153
L + R F +++ + G I+ + ++ V+G+ F+++G+ + L Y
Sbjct: 171 LHLRRITAGFLGMAVAVLLCGCIVATVSFFW-EESLTQHVAGLLFLMTGIFCTISLCTYA 229
Query: 154 SSINDEMLNRTK---DAETYFNYKYGWSF--AFAAISFLL 188
+SI+ ++ K + Y WS A+ ++ F++
Sbjct: 230 ASISYDLNRLPKLIYSLPADVEHGYSWSIFCAWCSLGFIV 269
Score = 29.6 bits (65), Expect = 3.3
Identities = 13/28 (46%), Positives = 18/28 (64%)
Query: 6 RKALTLLSSVFAVCGLGLLGIAVSTDYW 33
R +T LS ++C LGLL A+ TD+W
Sbjct: 4 RALVTALSLGLSLCSLGLLVTAIFTDHW 31
>gi|153792186 claudin 7 [Homo sapiens]
Length = 211
Score = 37.4 bits (85), Expect = 0.016
Identities = 35/165 (21%), Positives = 67/165 (40%), Gaps = 15/165 (9%)
Query: 20 GLGLLGIAVSTDYWLYLEEGVIVPQNQSTEIK-------MSLHSGLWRVCFLAGEERGRC 72
GL LLG +++ W+ L +PQ Q + +++ GLW C C
Sbjct: 5 GLQLLGFSMALLGWVGLVACTAIPQWQMSSYAGDNIITAQAMYKGLWMDCVTQSTGMMSC 64
Query: 73 FTIEYVMPMNTQLTSESTVNVLKMIRSATPFPLVSLFFMFIGFILNNIG-HIRPHRTILA 131
+ V+ ++ L + + V+ ++ +++F +G G + + +A
Sbjct: 65 KMYDSVLALSAALQATRALMVVSLVLG-----FLAMFVATMGMKCTRCGGDDKVKKARIA 119
Query: 132 FVSGIFFILSGLSLVVGLVLYISSINDEMLNRTKDAETYFNYKYG 176
GI FI++GL+ +V Y I + N T Y++G
Sbjct: 120 MGGGIIFIVAGLAALVACSWYGHQIVTDFYNPL--IPTNIKYEFG 162
>gi|5921465 claudin 10 isoform b [Homo sapiens]
Length = 228
Score = 37.4 bits (85), Expect = 0.016
Identities = 32/156 (20%), Positives = 61/156 (39%), Gaps = 13/156 (8%)
Query: 8 ALTLLSSVFAVCGLGLLGIAVSTDYWLYLEEGVIVPQNQSTEIKMSLH-SGLWRVCFLAG 66
A +++ + ++ G L+ + TDYW V T I + + + LW+ C
Sbjct: 5 ASEIIAFMVSISGWVLVSSTLPTDYWK-------VSTIDGTVITTATYWANLWKACVTDS 57
Query: 67 EERGRCFTIEYVMPMNTQLTSESTVNVLKMIRSATPFPLVSLFFMFIGFILNNIGHIRPH 126
C ++ ++ + + + + +A F G +G
Sbjct: 58 TGVSNCKDFPSMLALDGYIQACRGLMI-----AAVSLGFFGSIFALFGMKCTKVGGSDKA 112
Query: 127 RTILAFVSGIFFILSGLSLVVGLVLYISSINDEMLN 162
+ +A ++GI FILSGL + G LY + I E +
Sbjct: 113 KAKIACLAGIVFILSGLCSMTGCSLYANKITTEFFD 148
>gi|10863887 claudin 1 [Homo sapiens]
Length = 211
Score = 36.2 bits (82), Expect = 0.035
Identities = 32/180 (17%), Positives = 73/180 (40%), Gaps = 13/180 (7%)
Query: 17 AVCGLGLLGIAVSTDYWLYLEEGVIVPQ-------NQSTEIKMSLHSGLWRVCFLAGEER 69
A GL LLG ++ W+ +PQ + +++ GLW C +
Sbjct: 2 ANAGLQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTGQ 61
Query: 70 GRCFTIEYVMPMNTQLTSESTVNVLKMIRSATPFPLVSLFFMFIGF-ILNNIGHIRPHRT 128
+C + ++ +++ L + + V+ ++ ++++F +G + + +
Sbjct: 62 IQCKVFDSLLNLSSTLQATRALMVVGILLG-----VIAIFVATVGMKCMKCLEDDEVQKM 116
Query: 129 ILAFVSGIFFILSGLSLVVGLVLYISSINDEMLNRTKDAETYFNYKYGWSFAFAAISFLL 188
+A + G F+L+GL+++V Y + I E + + + +AA S L
Sbjct: 117 RMAVIGGAIFLLAGLAILVATAWYGNRIVQEFYDPMTPVNARYEFGQALFTGWAAASLCL 176
>gi|33598916 claudin 10 isoform a [Homo sapiens]
Length = 226
Score = 34.3 bits (77), Expect = 0.13
Identities = 35/149 (23%), Positives = 56/149 (37%), Gaps = 13/149 (8%)
Query: 15 VFAVCGLGLLGIAVSTDYWLYLEEGVIVPQNQSTEIKMSLHSGLWRVCFLAGEERGRCFT 74
V V G G L A +++ W + + S ++ GLW C AG G
Sbjct: 10 VSGVGGFGALVAATTSNEWK------VTTRASSVITATWVYQGLWMNC--AGNALGSF-- 59
Query: 75 IEYVMPMNTQLTSESTVNVLK-MIRSATPFPLVSLFFMFIGFILNNIGHIRPHRTILAFV 133
+ P T + + ++ +A F G +G + +A +
Sbjct: 60 --HCRPHFTIFKVAGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIACL 117
Query: 134 SGIFFILSGLSLVVGLVLYISSINDEMLN 162
+GI FILSGL + G LY + I E +
Sbjct: 118 AGIVFILSGLCSMTGCSLYANKITTEFFD 146
>gi|4502877 claudin 4 [Homo sapiens]
Length = 209
Score = 33.5 bits (75), Expect = 0.23
Identities = 27/138 (19%), Positives = 59/138 (42%), Gaps = 12/138 (8%)
Query: 17 AVCGLGLLGIAVSTDYWLYLEEGVIVPQNQSTEI-------KMSLHSGLWRVCFLAGEER 69
A GL ++GIA++ WL + +P + T ++ GLW C + +
Sbjct: 2 ASMGLQVMGIALAVLGWLAVMLCCALPMWRVTAFIGSNIVTSQTIWEGLWMNCVVQSTGQ 61
Query: 70 GRCFTIEYVMPMNTQLTSESTVNVLKMIRSATPFPLVSLFFMFIGFILNNIGHIRPHRTI 129
+C + ++ + L + + ++ +I +A + + +G N +
Sbjct: 62 MQCKVYDSLLALPQDLQAARALVIISIIVAA-----LGVLLSVVGGKCTNCLEDESAKAK 116
Query: 130 LAFVSGIFFILSGLSLVV 147
V+G+ F+L+GL ++V
Sbjct: 117 TMIVAGVVFLLAGLMVIV 134
>gi|239916002 lens intrinsic membrane protein 2, 19kDa isoform 2
[Homo sapiens]
Length = 173
Score = 33.1 bits (74), Expect = 0.30
Identities = 38/174 (21%), Positives = 68/174 (39%), Gaps = 42/174 (24%)
Query: 20 GLGLLGIAVSTDYWL-YLEEGVIVPQNQSTEIKMSLHSGLWRVCFLAGEERGRCFTIEYV 78
G LL +A++TD+W+ Y G H GLWR C +C+
Sbjct: 15 GTILLVVAMATDHWMQYRLSGSFA------------HQGLWRYCL-----GNKCY----- 52
Query: 79 MPMNTQLTSESTVNVLKMIRSATPFPLVSLFFMFIGFILNNIGHIRP---HRTILAFVSG 135
L ++S + + F ++S G I+ + R F +G
Sbjct: 53 ------LQTDS----IAYWNATRAFMILSALCAISGIIMGIMAFAHQPTFSRISRPFSAG 102
Query: 136 IFFILSGLSLVVGLVLYISSINDEMLNRTKDAETYFNYKYGWSFAFAAISFLLT 189
I F S L +V+ L +Y + + L R + ++++ WS+ ++ L+T
Sbjct: 103 IMFFSSTLFVVLALAIY-TGVTVSFLGR-----RFGDWRFSWSYILGWVAVLMT 150
>gi|116292168 KRAB A domain containing 1 [Homo sapiens]
Length = 1030
Score = 33.1 bits (74), Expect = 0.30
Identities = 31/88 (35%), Positives = 37/88 (42%), Gaps = 12/88 (13%)
Query: 204 GTAPLSRGEWGWGRRDIPQPFWTPDHPLYFPSSSQNVSL-SYLSGSPPARMSPGPCSCPH 262
G PLS G R +PQP W P+ SSS +L + L G PP SP
Sbjct: 350 GRQPLSPSATG-DTRGVPQPSWGPEAQAASASSSPLEALEACLKGIPPNGSSPSQL---- 404
Query: 263 VHFPPHSSCVLCRPQPREMR-QAPAASP 289
P +SC PQP + R Q P P
Sbjct: 405 ----PPTSCSQ-NPQPGDSRSQKPELQP 427
>gi|93588657 claudin domain containing 1 protein isoform d [Homo
sapiens]
Length = 158
Score = 32.3 bits (72), Expect = 0.51
Identities = 23/83 (27%), Positives = 43/83 (51%), Gaps = 5/83 (6%)
Query: 104 PLVSLFFMFIGFILNNIGHIRPHRTILAFVS-GIFFILSGLSLVVGLVLYISSINDEMLN 162
P VSL M G ++ I R++ ++ GI +L+GL + + Y++ I E+L+
Sbjct: 49 PFVSLGLMCFGALIGLCACIC--RSLYPTIATGILHLLAGLCTLGSVSCYVAGI--ELLH 104
Query: 163 RTKDAETYFNYKYGWSFAFAAIS 185
+ + + ++GWSF A +S
Sbjct: 105 QKLELPDNVSGEFGWSFCLACVS 127
>gi|93588650 claudin domain containing 1 protein isoform a [Homo
sapiens]
Length = 253
Score = 32.3 bits (72), Expect = 0.51
Identities = 23/83 (27%), Positives = 43/83 (51%), Gaps = 5/83 (6%)
Query: 104 PLVSLFFMFIGFILNNIGHIRPHRTILAFVS-GIFFILSGLSLVVGLVLYISSINDEMLN 162
P VSL M G ++ I R++ ++ GI +L+GL + + Y++ I E+L+
Sbjct: 144 PFVSLGLMCFGALIGLCACIC--RSLYPTIATGILHLLAGLCTLGSVSCYVAGI--ELLH 199
Query: 163 RTKDAETYFNYKYGWSFAFAAIS 185
+ + + ++GWSF A +S
Sbjct: 200 QKLELPDNVSGEFGWSFCLACVS 222
>gi|93588620 claudin domain containing 1 protein isoform b [Homo
sapiens]
Length = 276
Score = 32.3 bits (72), Expect = 0.51
Identities = 23/83 (27%), Positives = 43/83 (51%), Gaps = 5/83 (6%)
Query: 104 PLVSLFFMFIGFILNNIGHIRPHRTILAFVS-GIFFILSGLSLVVGLVLYISSINDEMLN 162
P VSL M G ++ I R++ ++ GI +L+GL + + Y++ I E+L+
Sbjct: 167 PFVSLGLMCFGALIGLCACIC--RSLYPTIATGILHLLAGLCTLGSVSCYVAGI--ELLH 222
Query: 163 RTKDAETYFNYKYGWSFAFAAIS 185
+ + + ++GWSF A +S
Sbjct: 223 QKLELPDNVSGEFGWSFCLACVS 245
>gi|93588614 claudin domain containing 1 protein isoform a [Homo
sapiens]
Length = 253
Score = 32.3 bits (72), Expect = 0.51
Identities = 23/83 (27%), Positives = 43/83 (51%), Gaps = 5/83 (6%)
Query: 104 PLVSLFFMFIGFILNNIGHIRPHRTILAFVS-GIFFILSGLSLVVGLVLYISSINDEMLN 162
P VSL M G ++ I R++ ++ GI +L+GL + + Y++ I E+L+
Sbjct: 144 PFVSLGLMCFGALIGLCACIC--RSLYPTIATGILHLLAGLCTLGSVSCYVAGI--ELLH 199
Query: 163 RTKDAETYFNYKYGWSFAFAAIS 185
+ + + ++GWSF A +S
Sbjct: 200 QKLELPDNVSGEFGWSFCLACVS 222
>gi|93588624 claudin domain containing 1 protein isoform a [Homo
sapiens]
Length = 253
Score = 32.3 bits (72), Expect = 0.51
Identities = 23/83 (27%), Positives = 43/83 (51%), Gaps = 5/83 (6%)
Query: 104 PLVSLFFMFIGFILNNIGHIRPHRTILAFVS-GIFFILSGLSLVVGLVLYISSINDEMLN 162
P VSL M G ++ I R++ ++ GI +L+GL + + Y++ I E+L+
Sbjct: 144 PFVSLGLMCFGALIGLCACIC--RSLYPTIATGILHLLAGLCTLGSVSCYVAGI--ELLH 199
Query: 163 RTKDAETYFNYKYGWSFAFAAIS 185
+ + + ++GWSF A +S
Sbjct: 200 QKLELPDNVSGEFGWSFCLACVS 222
>gi|11096340 claudin domain containing 1 protein isoform a [Homo
sapiens]
Length = 253
Score = 32.3 bits (72), Expect = 0.51
Identities = 23/83 (27%), Positives = 43/83 (51%), Gaps = 5/83 (6%)
Query: 104 PLVSLFFMFIGFILNNIGHIRPHRTILAFVS-GIFFILSGLSLVVGLVLYISSINDEMLN 162
P VSL M G ++ I R++ ++ GI +L+GL + + Y++ I E+L+
Sbjct: 144 PFVSLGLMCFGALIGLCACIC--RSLYPTIATGILHLLAGLCTLGSVSCYVAGI--ELLH 199
Query: 163 RTKDAETYFNYKYGWSFAFAAIS 185
+ + + ++GWSF A +S
Sbjct: 200 QKLELPDNVSGEFGWSFCLACVS 222
>gi|231569235 claudin 10 isoform a_i1 [Homo sapiens]
Length = 207
Score = 32.0 bits (71), Expect = 0.67
Identities = 19/56 (33%), Positives = 29/56 (51%), Gaps = 1/56 (1%)
Query: 107 SLFFMFIGFILNNIGHIRPHRTILAFVSGIFFILSGLSLVVGLVLYISSINDEMLN 162
S+F +F G +G + +A ++GI FILSGL + G LY + I E +
Sbjct: 73 SIFALF-GMKCTKVGGSDKAKAKIACLAGIVFILSGLCSMTGCSLYANKITTEFFD 127
>gi|4505907 peripheral myelin protein 22 [Homo sapiens]
Length = 160
Score = 31.6 bits (70), Expect = 0.87
Identities = 43/182 (23%), Positives = 70/182 (38%), Gaps = 51/182 (28%)
Query: 8 ALTLLSSVFAVCGLGLLGIAVSTDYWLYLEEGVIVPQNQSTEIKMSLHSGLWRVCFLAGE 67
A+ +L V + ++G +TD W QN ST ++H CF +
Sbjct: 14 AVLVLLFVSTIVSQWIVGNGHATDLW----------QNCSTSSSGNVHH-----CFSSSP 58
Query: 68 ERGRCFTIEYVMPMNTQLTSESTVNVLKMIRSATPFPLVSLFFMFIG-FILNNIGHIRPH 126
N L S +L +I F ++SLF F F L G
Sbjct: 59 --------------NEWLQSVQATMILSII-----FSILSLFLFFCQLFTLTKGGRF--- 96
Query: 127 RTILAFVSGIFFILSGLSLVVGLVLYISSINDEMLNRTKDAETYFNYKYGWSFAFAAISF 186
+++GIF IL+GL ++ +Y + LN +Y YG+++ A ++F
Sbjct: 97 -----YITGIFQILAGLCVMSAAAIYTVRHPEWHLNS--------DYSYGFAYILAWVAF 143
Query: 187 LL 188
L
Sbjct: 144 PL 145
>gi|24430165 peripheral myelin protein 22 [Homo sapiens]
Length = 160
Score = 31.6 bits (70), Expect = 0.87
Identities = 43/182 (23%), Positives = 70/182 (38%), Gaps = 51/182 (28%)
Query: 8 ALTLLSSVFAVCGLGLLGIAVSTDYWLYLEEGVIVPQNQSTEIKMSLHSGLWRVCFLAGE 67
A+ +L V + ++G +TD W QN ST ++H CF +
Sbjct: 14 AVLVLLFVSTIVSQWIVGNGHATDLW----------QNCSTSSSGNVHH-----CFSSSP 58
Query: 68 ERGRCFTIEYVMPMNTQLTSESTVNVLKMIRSATPFPLVSLFFMFIG-FILNNIGHIRPH 126
N L S +L +I F ++SLF F F L G
Sbjct: 59 --------------NEWLQSVQATMILSII-----FSILSLFLFFCQLFTLTKGGRF--- 96
Query: 127 RTILAFVSGIFFILSGLSLVVGLVLYISSINDEMLNRTKDAETYFNYKYGWSFAFAAISF 186
+++GIF IL+GL ++ +Y + LN +Y YG+++ A ++F
Sbjct: 97 -----YITGIFQILAGLCVMSAAAIYTVRHPEWHLNS--------DYSYGFAYILAWVAF 143
Query: 187 LL 188
L
Sbjct: 144 PL 145
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.138 0.439
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,880,988
Number of Sequences: 37866
Number of extensions: 590030
Number of successful extensions: 2862
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 66
Number of HSP's that attempted gapping in prelim test: 2789
Number of HSP's gapped (non-prelim): 119
length of query: 296
length of database: 18,247,518
effective HSP length: 102
effective length of query: 194
effective length of database: 14,385,186
effective search space: 2790726084
effective search space used: 2790726084
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.